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Publications (101)388.49 Total impact
Article: Blastocyst versus cleavage-stage elective single embryo transfer - a comparative retrospective study
Article: Physical health of singleton children born after frozen embryo transfer using slow freezing: A 3-year follow-up study[Show abstract] [Hide abstract]
ABSTRACT: Are there differences in the physical health of singleton children born after frozen embryo transfer (FET) compared with children born after fresh embryo transfer (fresh ET)? Register-based health indicators were similar among FET and fresh ET singletons during a 3-year follow-up. Large cohort studies have shown that perinatal outcomes are similar or even better in FET than fresh ET children. The early childhood morbidity among FET and fresh ET children has been shown to be quite similar, but so far these studies have been small. The short-term health outcomes of assisted reproductive technology (ART) children have been shown to be slightly worse compared with spontaneously conceived children. This register-based study includes women who had undergone ART treatments leading to singleton live births (n = 4758 children) in 1995-2006. A 10% random sample of women with spontaneous pregnancies from the Finnish Medical Birth Register (FMBR) served as the reference group (n = 31 137 children). The children were identified through the FMBR by using the mother's personal identification (ID) number. Children's ID numbers were linked with two nationwide registries; the Finnish Hospital Discharge Register and the Cause-of-Death Register at Statistics Finland. Information on all visits was received until 2009 using ICD-10 codes. The study includes 1825 children born after FET, 2933 children born after fresh ET and 31 137 children born after spontaneous pregnancies. The risk estimates for diseases were adjusted for the child's year of birth and maternal age, parity, socio-economic status and prematurity. The study focused on the differences between FET and fresh ET children. Most health indicators were similar among FET and fresh ET children during the 3-year follow-up. The most common discharge diagnoses, including gastroenteritis and colitis, otitis, upper and lower respiratory diseases, asthma and allergies were similar between the ART groups. A large proportion of FET children (70.1%) and fresh ET children (69.9%) had visited a hospital at least once (P = 0.877). The risk of hospital admission did not differ between the two groups after adjusting for premature births [adjusted odds ratio (aOR) 1.01; 0.88-1.17]. Comparing with children born after spontaneously conceived pregnancies, the risk of hospital admission was slightly increased in the ART group, even after adjusting for premature births (aOR 1.10; 1.02-1.19). Due to the study design, we were not able to control for some parental background factors, such as the cause and length of infertility. Furthermore, the health registries do not include data on the growth of the children. Our findings are generalizable only to the slow-freezing method. Our study provides further evidence of the safety of embryo cryopreservation. The early physical health of FET children is similar to that of children born after fresh ET. This study was funded by the University Hospital of Oulu and Helsinki, Finland. The National Institute for Health and Welfare (THL) covered the data linkages and the work of Mika Gissler. There are no competing interests to be reported. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: email@example.com Reproduction 08/2015; 30(10). DOI:10.1093/humrep/dev203 · 4.57 Impact Factor
Article: Major congenital anomalies in children born after frozen embryo transfer: A cohort study 1995-2006[Show abstract] [Hide abstract]
ABSTRACT: Is there a different risk for major congenital anomalies (CAs) in children born after frozen-thawed embryo transfer (FET) compared with children born after fresh embryo transfer (ET)? Children born after FET have a similar risk of developing major CAs as children born after fresh ET. The perinatal outcome in children born after FET is as good as that after fresh ET. Children born as a result of assisted reproductive technology (ART) have an increased risk for CAs when compared with spontaneously conceived children, but the knowledge on the risk for CAs in specific organ systems of children born after FET is limited. This register-based cohort study includes women who have undergone ART treatments with ET leading to singleton births (n = 4772) between the years 1995 and 2006. The women were identified from the registers of the infertility clinics, and the corresponding births were matched with data from the Finnish Medical Birth Register (FMBR). The 10% random sample of women with spontaneous pregnancies from the FMBR served as the reference group (n = 31 243). The study data were linked with the Register of Congenital Malformations using the mothers' and children's personal identification numbers to get information on CAs. Furthermore, the personal identification numbers of the ART women were linked with the Register of Induced Abortions to find their selective terminations of pregnancy for severe foetal anomalies. The study was focused on singleton births and included 1830 children born after FET, 2942 children born after fresh ET and 31 243 children born after spontaneous pregnancies. Only major CAs were analysed in keeping with European Concerted Action on Congenital Anomalies and Twins. The risk estimates for CAs were adjusted for the children's year of birth and maternal age, parity and socioeconomic status. The total prevalence of major CAs was counted, including both births and selective terminations of pregnancy for major fetal anomalies (n = 33). Among singletons at least one major CA was reported in 77 cases (4.2%) in the FET group, 132 cases (4.5%) in the fresh ET group and 994 cases (3.2%) in the reference group. The risk for at least one major CA of the children born after FET was not increased compared with the children born after fresh ET [adjusted odd ratio (aOR) 0.95; 0.71-1.27]. Furthermore, no increased risks according to the organ system affected were found between these two ART groups. When comparing the children born after ART (FET and fresh ET) with the reference group children, the risk of having at least one major CA was moderately increased in the ART group (aOR 1.24; 1.05-1.47). Because of the study design we were neither able to examine the aetiology of infertility nor could we compare the data with a group of subfertile women to account for the effect of infertility per se on CAs. Perinatal outcomes of FET children, including the risks for CAs, are good and comparable with outcomes of other ART children indicating that slow freezing is a safe method to use during ART treatments. University Hospital of Oulu and Helsinki, Finland. THL covered the data linkages and the work of Annukka Ritvanen and Mika Gissler. There are no competing interests to be reported.Human Reproduction 05/2014; 29(7). DOI:10.1093/humrep/deu088 · 4.57 Impact Factor
- Human Reproduction 01/2013; 28(4). DOI:10.1093/humrep/des470 · 4.57 Impact Factor
Dataset: BJC09
- [Show abstract] [Hide abstract]
ABSTRACT: Is an elective single-embryo transfer (eSET) policy feasible for women aged 40 or older? For older women (aged 4044 years) with a good prognosis, an eSET policy can be applied with acceptable cumulative clinical pregnancy rates and live birth rates. Various studies have shown the effectiveness of eSET in women aged 35 years with high cumulative pregnancy rates and low rates of multiple births. This retrospective cohort study included 628 women treated between 2000 and 2009. Women aged 4044 years underwent a fresh cycle of IVF or ICSI treatment with eSET (n 264) or double-embryo transfer (DET) (n 364). In the subsequent frozen-thawed embryo transfer cycles, SET/DET was performed in both groups according to the number of embryos available and the opinion of the couple. The study was performed at the Family Federation of Finland Helsinki Fertility Clinic. In the fresh cycles, the clinical pregnancy rates were 23.5 and 19.5 in the eSET and DET groups, respectively, and live birth rates were 13.6 and 11.0, respectively. In the fresh cycles with eSET, there were no twin pregnancies, but in the DET group, there were three sets of twins (7.5). The cumulative clinical pregnancy rates per oocyte retrieval were 37.1 and 24.2 in the eSET and DET groups, respectively (P 0.001), and the cumulative live birth rates were 22.7 and 13.2, respectively (P 0.002). Cumulative twin rates were 6.7 (n 4) in the eSET group and 8.3 (n 4) in the DET group (P 0.726). All of the twin pregnancies in the eSET group resulted from frozen and thawed DET embryo transfer cycles. The characteristics of the two patients groups are not comparable because the suitability of eSET was individually assessed by a clinician based on both clinical prognostic factors and the outcome of IVF or ICSI, i.e. the number and quality of embryos. This study may be generalized to IVF units having experience in eSET and cryopreservation. This study received no funding and there are no conflicts of interests to be declared.Human Reproduction 11/2012; 28(2). DOI:10.1093/humrep/des399 · 4.57 Impact Factor
Article: Menstrual disorders in adolescence: A marker for hyperandrogenaemia and increased metabolic risks in later life? Finnish general population-based birth cohort study[Show abstract] [Hide abstract]
ABSTRACT: Are self-reported menstrual disorders associated with hyperandrogenaemia and metabolic disturbances as early as in adolescence? SUMMARY ANSWER: Menstrual disorders at the age 16 are a good marker of hyperandrogenaemia, and an adverse lipid profile was associated with higher androgen levels. WHAT IS KNOWN AND WHAT THIS PAPER ADDS: Hyperandrogenism per se has been suggested to be a significant metabolic risk factor in women and a cause of physical and psychological morbidity in adolescent girls. A weak positive correlation has been described between hyperandrogenaemia and obesity in adolescent girls, but the clinical consequences are still poorly understood. Hyperandrogenism and insulin resistance are also key features of polycystic ovary syndrome (PCOS), and women with PCOS are consequently at an increased risk of developing type 2 diabetes mellitus and/or metabolic syndrome, and may have increased cardiovascular morbidity. Our findings confirm that the association between menstrual disorders, hyperandrogenism, obesity and metabolic risks is already evident in adolescence. This population-based, cross-sectional study used postal questionnaires to targeting 15-16-year-old girls in the Northern Finland Birth Cohort 1986 (n= 4567). There were 3669 girls who answered the postal questionnaire and out of 3373 girls who also underwent clinical examinations and blood tests, 2448 were included in the analyses. The questionnaire included one question about the regularity and length of the menstrual cycle: 'Is your menstrual cycle (the interval from the beginning of one menstrual period to the beginning of the next period) often (more than twice a year) longer than 35 days?' The girls who answered 'yes' to this question were considered to be suffering from menstrual disorders and were classified as 'symptomatic'. The girls who answered 'no' were defined as 'non-symptomatic'. MAIN RESULTS AND THE ROLE OF CHANCE: There were 709 (29%) girls who reported menstrual disorders (symptomatic girls) and 1739 who had regular periods (non-symptomatic girls). In the whole population and in both study groups, there were significant correlations between body mass index (BMI) (and waist-to-hip ratio), hyperandrogenaemia and metabolic parameters. Symptomatic girls exhibited significantly higher serum concentrations of testosterone (P= 0.010), lower levels of sex hormone-binding globulin (P =0.042) and higher free androgen indices [FAIs; geometric mean 3.38 (interquartile range (IQR): 2.27, 5.18) versus 3.08 (IQR: 2.15, 4.74), P= 0.002]. The two groups had comparable BMI and insulin sensitivity, and serum levels of glucose, insulin and lipids. There was a significant linear trend towards higher FAI values in the higher BMI quartiles in both symptomatic and non-symptomatic girls. In the whole population, there was a statistically significant linear decrease in high-density lipoprotein concentrations (P < 0.001) and higher triglyceride concentrations (P =0.004) in the upper FAI quartile. Information regarding menstrual disorders in adolescence is a good marker of hyperandrogenaemia and may be an early risk factor for the development of PCOS in adulthood. The association between obesity, hyperandrogenism and metabolic risks is already evident in adolescence, which strengthens the importance of noting menstrual disorders at an early stage. BIAS, LIMITATIONS, GENERALIZABILITY: The cross-sectional nature of the study does not allow us to draw conclusions concerning the metabolic risks of this population in later life. The diagnosis of menstrual disorders was based on a questionnaire, suggesting a risk of information bias in reporting the symptoms. This study was not designed to diagnose PCOS, as ultrasonography was not available and there was no clinical evaluation of hyperandrogenism (i.e. hirsutism). However, we were able to take into account potential confounding factors in the analyses. STUDY FUNDING/COMPETING INTERESTS: This work was supported by grants from the Finnish Medical Society Duodecim, the North Ostrobothnia Regional Fund, the Academy of Finland (project grants 104781, 120315, 129269, 1114194, SALVE), University Hospital Oulu, Biocenter, University of Oulu, Finland (75617), the European Commission (EURO-BLCS, Framework 5 award QLG1-CT-2000-01643) and the Medical Research Council, UK (PrevMetSyn/SALVE). None of the authors have any conflict of interest to declare.Human Reproduction 08/2012; 27(11):3279-86. DOI:10.1093/humrep/des309 · 4.57 Impact Factor
- Fertility and Sterility 09/2011; 96(3). DOI:10.1016/j.fertnstert.2011.07.804 · 4.59 Impact Factor
Article: Clinical effectiveness of elective single versus double embryo transfer: Meta-analysis of individual patient data from randomised trials[Show abstract] [Hide abstract]
ABSTRACT: To compare the effectiveness of elective single embryo transfer versus double embryo transfer on the outcomes of live birth, multiple live birth, miscarriage, preterm birth, term singleton birth, and low birth weight after fresh embryo transfer, and on the outcomes of cumulative live birth and multiple live birth after fresh and frozen embryo transfers. One stage meta-analysis of individual patient data. A systematic review of English and non-English articles from Medline, Embase, and the Cochrane Central Register of Controlled Trials (up to 2008). Additional studies were identified by contact with clinical experts and searches of bibliographies of all relevant primary articles. Search terms included embryo transfer, randomised controlled trial, controlled clinical trial, single embryo transfer, and double embryo transfer. Review methods Comparisons of the clinical effectiveness of cleavage stage (day 2 or 3) elective single versus double embryo transfer after fresh or frozen in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) treatments were included. Trials were included if the intervention differed only in terms of the intended number of embryos to be transferred. Trials that involved only blastocyst (day five) transfers were excluded. Individual patient data were received for every patient recruited to all eight eligible trials (n=1367). A total of 683 and 684 women randomised to the single and double embryo transfer arms, respectively, were included in the analysis. Baseline characteristics in the two groups were comparable. The overall live birth rate in a fresh IVF cycle was lower after single (181/683, 27%) than double embryo transfer (285/683, 42%) (adjusted odds ratio 0.50, 95% confidence interval 0.39 to 0.63), as was the multiple birth rate (3/181 (2%) v 84/285 (29%)) (0.04, 0.01 to 0.12). An additional frozen single embryo transfer, however, resulted in a cumulative live birth rate not significantly lower than the rate after one fresh double embryo transfer (132/350 (38%) v 149/353 (42%) (0.85, 0.62 to 1.15), with a minimal cumulative risk of multiple birth (1/132 (1%) v 47/149 (32%)). The odds of a term singleton birth (that is, over 37 weeks) after elective single embryo transfer was almost five times higher than the odds after double embryo transfer (4.93, 2.98 to 8.18). Elective single embryo transfer results in a higher chance of delivering a term singleton live birth compared with double embryo transfer. Although this strategy yields a lower pregnancy rate than a double embryo transfer in a fresh IVF cycle, this difference is almost completely overcome by an additional frozen single embryo transfer cycle. The multiple pregnancy rate after elective single embryo transfer is comparable with that observed in spontaneous pregnancies.BMJ (online) 12/2010; 341(dec21 2):c6945. DOI:10.1136/bmj.c6945 · 17.45 Impact Factor
Article: Perinatal outcome of children born after frozen and fresh embryo transfer: The Finnish cohort study 1995-2006[Show abstract] [Hide abstract]
ABSTRACT: The number of children born after frozen embryo transfer (FET) is steadily rising. However, studies on obstetric and perinatal outcomes are limited. Our primary aim was to compare the perinatal health of children born after FET and fresh embryo transfer, and to use data from children born after spontaneous conception as a reference. In a register-based cohort study we evaluated the obstetric and perinatal outcomes of children born after FET (n = 2293), fresh embryo transfer (n = 4151) and those born after spontaneous pregnancy (reference group; n = 31 946). Data were collected from the registers of two infertility outpatient clinics, two university hospitals and the Finnish Medical Birth Register (1995-2006). After adjusting for confounding factors the FET group showed decreased risks of preterm birth [adjusted odd ratio (AOR) 0.83, 95% confidence interval (CI) 0.71-0.97], low birthweight (AOR 0.74; 0.62-0.88) and being small for gestational age (AOR 0.63; 0.49-0.83) compared with the fresh embryo transfer group. Mean birthweight was 134 g higher in the FET singletons versus the fresh embryo transfer singletons (P< 0.0001). When FET singletons were compared with the reference group, increased risks of preterm birth (AOR 1.45; 1.25-1.68) and low birthweight (AOR 1.22; 1.03-1.45) and a decreased risk of being small for gestational age (AOR 0.71; 0.54-0.92) were found. No excess of perinatal and infant mortality occurred between the groups. Embryo freezing does not adversely affect perinatal outcome in terms of prematurity, low birthweight and being small for gestational age versus the fresh embryo transfer and the outcome is similar or even better, particularly regarding fetal growth. Our study, which is one of the largest on FET pregnancies, provides further evidence on the safety of FET.Human Reproduction 04/2010; 25(4):914-23. DOI:10.1093/humrep/dep477 · 4.57 Impact Factor
Article: Low-dose aspirin reduces uteroplacental vascular impedance in early and mid gestation in IVF and ICSI patients: A randomized, placebo-controlled double-blind study[Show abstract] [Hide abstract]
ABSTRACT: To determine whether low-dose aspirin improves uteroplacental hemodynamics in unselected in-vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) subjects when medication is started concomitantly with controlled ovarian hyperstimulation. Thirty-seven pregnant women who had undergone IVF/ICSI and had been randomized to receive 100 mg aspirin (n = 17) or placebo (n = 20) daily, started concomitantly with controlled ovarian hyperstimulation, were included in this study. Doppler ultrasound examination was performed at 6, 10, 13 and 18 weeks' gestation. Uterine artery (UtA) pulsatility index (PI) was calculated and bilateral UtA notching was noted. Subplacental arcuate artery PI was obtained at 6 and 10 weeks' gestation. Umbilical artery (UA) PI and mean velocity were calculated at 10, 13 and 18 weeks' gestation. In the aspirin group there was one early pregnancy miscarriage, and one patient discontinued the study medication owing to early pregnancy bleeding. A total of 15 women in the aspirin group and 20 women in the placebo group underwent the complete ultrasound protocol. At 6 weeks' gestation, arcuate artery PI and at 18 weeks' gestation, UtA PI were lower (P < 0.05) in the aspirin group than in the placebo group. At 18 weeks' gestation, bilateral UtA notching tended to be more common in the placebo group (40%) than in the aspirin group (13%) (P = 0.06). UA PI and mean velocity did not differ significantly between the groups. Low-dose aspirin reduces uteroplacental vascular impedance in early and mid pregnancy in unselected IVF/ICSI subjects when medication is started concomitantly with controlled ovarian hyperstimulation.Ultrasound in Obstetrics and Gynecology 10/2008; 32(5):687-93. DOI:10.1002/uog.6215 · 3.85 Impact Factor
Article: Obstetric and Perinatal Outcomes of children born after the transfer of cryopreserved and fresh embryosFertility and Sterility 09/2008; 90. DOI:10.1016/j.fertnstert.2008.07.809 · 4.59 Impact Factor
Article: Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome[Show abstract] [Hide abstract]
ABSTRACT: Variants in the fat-mass and obesity-associated gene (FTO) influence susceptibility to type 2 diabetes via an effect on adiposity/obesity. Given the important role of obesity in the aetiology of both polycystic ovary syndrome (PCOS) and type 2 diabetes mellitus, our aim was to establish whether FTO variants are also implicated in PCOS susceptibility. We performed a genetic association study of FTO variant rs9939609 using case-control analyses, conducted in 463 PCOS patients (geometric mean BMI 27.5 kg/m(2)) and 1,336 female controls (geometric mean BMI 25.3 kg/m(2)) of UK British/Irish origin. We also sought evidence for associations between FTO variation and circulating testosterone levels in 324 UK PCOS patients and 1,000 women from the Northern Finland Birth Cohort of 1966. Outcome measures included FTO rs9939609 genotype frequencies by participant group and androgen measures (testosterone, free androgen index) by genotype. There was a significant association between FTO genotype and PCOS status in the UK case-control analysis, which was attenuated by adjustment for BMI (Cochran-Armitage test, odds ratio [per minor allele copy] 1.30 [95% CI 1.12, 1.51], p = 7.2 x 10(-4) [unadjusted], p = 2.9 x 10(-3) [adjusted]). This association was most evident in obese PCOS patients (PCOS patients below median BMI vs UK controls, p = 0.11; above median BMI vs controls, p = 2.9 x 10(-4)). No relationship between FTO genotype and androgen levels was seen. We provide the first evidence that variants that predispose to common obesity also result in altered susceptibility to PCOS, confirming the mechanistic link between these conditions. The predominant effect of FTO variants on PCOS susceptibility is probably mediated through adiposity.Diabetologia 08/2008; 51(7):1153-8. DOI:10.1007/s00125-008-1028-6 · 6.67 Impact Factor
Article: Fecundability and spontaneous abortions in women with self-reported oligo-amenorrhea and/or hirsutism: Northern Finland Birth Cohort 1966 Study[Show abstract] [Hide abstract]
ABSTRACT: Women with polycystic ovary syndrome (PCOS) suffer from anovulatory infertility and hospital-based studies suggest that they have an increased risk of spontaneous abortion. Our aim was to investigate the proportion of women, with self-reported oligo-amenorrhea and/or hirsutism in a general population, who had suffered from infertility, the percentage of them managing to conceive and their rate of spontaneous abortion. At age 31, a postal questionnaire including questions about hirsutism and oligo-amenorrhea was sent to all women from the population-based Northern Finland Birth Cohort 1966 (total n = 5889). Of these, 4535 (79.5%) answered the questionnaire, 1103 reported hirsutism and/or oligo/amenorrhea (symptomatic women) and 3420 were non-symptomatic. The fecundability ratio (FR) was defined as the probability of conception of a clinically detectable pregnancy within 12 months. The overall pregnancy (77.7% versus 75.6%) and spontaneous abortion (19.3% versus 18.6%) rates did not differ between the two groups and the risk of spontaneous abortion was not associated with body mass index (BMI), waist-to-hip ratio (WHR) or waist circumference. Symptomatic women had suffered more often from infertility than non-symptomatic women (19.4% versus 11.1%, P < 0.01). Oligo-amenorrhea and/or hirsutism (FR = 0.74, P < 0.001) and obesity (FR = 0.68, P = 0.002) were both independently associated with decreased fecundability, but symptomatic women had become pregnant and had one or two successful deliveries as often as non-symptomatic women. Women with self-reported oligo-amenorrhea and/or hirsutism had lower fecundability and suffered more often from infertility, but had at least one delivery as often as non-symptomatic women, and did not exhibit an increased risk of spontaneous abortion.Human Reproduction 06/2008; 23(9):2134-9. DOI:10.1093/humrep/den136 · 4.57 Impact Factor
Article: No evidence that established Type 2 diabetes susceptibility variants in the PPARG and KCNJ11 genes have pleiotropic effects on early growth[Show abstract] [Hide abstract]
ABSTRACT: The P12A variant in the PPARG gene and the E23K polymorphism in KCNJ11 are both known to influence individual predisposition to type 2 diabetes. If the effect of these variants on insulin secretion and action were to extend to an influence on early growth (which is largely mediated by insulin), it would offer an explanation for observed associations between low birthweight and subsequent diabetes. Since previous studies of the effects of these variants on early growth have been limited and conflicting, we examined these associations in a large, well-characterised birth cohort. The P12A and E23K variants were genotyped in (respectively) 5,652 and 5,632 individuals from the Northern Finland Birth Cohort of 1966 and we sought associations with early growth phenotypes. Neither variant was associated with birthweight (P12A, p = 0.42; E23K, p = 0.44, additive models) or other measures of early growth. Although a previous report had suggested that the P12A effect on adult insulin sensitivity was restricted to small babies, we were unable to reproduce this finding (p = 0.40), nor did we confirm a previous report of an association with gestational age (p = 0.23). Despite a larger sample size than previous studies, we were unable to detect any effect of these variants on early growth. These findings do not support the notion that there are shared genetic determinants of low birthweight and adult diabetes.Diabetologia 02/2008; 51(1):82-5. DOI:10.1007/s00125-007-0863-1 · 6.67 Impact Factor
Article: Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS[Show abstract] [Hide abstract]
ABSTRACT: Common variants of the gene encoding transcription factor 7-like 2 (TCF7L2) have a powerful effect on individual risk of type 2 diabetes (per allele odds ratio approximately 1.35). Polycystic ovary syndrome (PCOS) and type 2 diabetes are familial conditions sharing common features. Based on this, the aim of the present study was to establish whether variation in TCF7L2 also influences the development of PCOS. We conducted a genetic association study of variants of TCF7L2 (rs7903146 and rs12255372) using both case-control and quantitative trait approaches. Case-control analyses were conducted in (1) 369 PCOS cases and 2574 controls of UK British/Irish origin, and (2) 540 women with PCOS symptoms and 1083 controls from the Northern Finland Birth Cohort of 1966. Quantitative trait analyses (androgen levels) were also performed (1249 individuals). There was no association between rs7903146 and PCOS in the UK case-control study (Cochran-Armitage test, p = 0.51); nor with symptomatic status in the Finnish cohort (p = 0.36). In addition, there were no relationships between the TCF7L2 single nucleotide polymorphism rs7903146 and androgen levels (UK cases, p = 0.99; Finnish controls, p = 0.57; Finnish symptomatic cases, p = 0.80). Results at rs12255372 were similar, reflecting strong linkage disequilibrium with rs7903146. Our study was powered to detect an effect on PCOS susceptibility similar to that previously reported for these variants on type 2 diabetes. Failure to detect any evident association with PCOS provides the strongest evidence yet that the genetic architecture of these related conditions is qualitatively distinct.Diabetologia 12/2007; 50(11):2318-22. DOI:10.1007/s00125-007-0804-z · 6.67 Impact Factor
- Fertility and Sterility 09/2007; 88. DOI:10.1016/j.fertnstert.2007.07.313 · 4.59 Impact Factor
Article: OP20.06: Ovarian response to hCG stimulation test in normal ovulatory women: the impact of regressing corpus luteumUltrasound in Obstetrics and Gynecology 09/2006; 28(4):505-505. DOI:10.1002/uog.3364 · 3.85 Impact Factor
Article: O-33 : Should long-term hormonal contraception be reconsidered? Metabolic and inflammatory outcomes in women using oral contraceptives and the levonorgestrel-releasing intrauterine device in a general populationFertility and Sterility 09/2006; 86(3):S15. DOI:10.1016/j.fertnstert.2006.07.041 · 4.59 Impact Factor
Article: P-316
Top Journals
University of Oulu
Uleoborg, Northern Ostrobothnia, Finland
- • Department of Obstetrics and Gynaecology
- • Department of Clinical Chemistry
Oulu University Hospital
Uleoborg, Oulu, Finland
- Department of Obstetrics and Gynecology
University of Turku
Turku, Varsinais-Suomi, Finland
- Department of Physiology
Helsinki University Central Hospital
Helsinki, Uusimaa, Finland
- Department of Obstetrics and Gynaecology


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Photos: From young surfer to AL champion - a look at Ian Kinsler
Photo: LOUIS DELUCA / Staff Photographer
Rangers presient Nolan Ryan and 2B Ian Kinsler are pictured before the Baltimore Orioles vs. Texas Rangers major league baseball game at Rangers Balpark in Arlington on Saturday, July 10, 2010.
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subset: commoncrawl


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When I first started all of this, I thought I was doing this for me. But thinking about it here for a while, I finally know it wasn't. It was for everyone who thought I couldn't, for people who had doubts, concerns.....for people who I wanted to make proud. For everyone....but myself. And because of that, I've gained the weight back. I feel ashamed and saddened that I've gained that much weight . I don't want to admit it to myself let alone to any of you.
I have failed....miserably.
Looking back though, I'm glad I figured this out now. I haven't gained all the weight back. I'm not at square one, however I have learned through therapy and self discovery that this time it has to be for myself if I'm gonna keep the weight off. So I've spent the last few months finding myself. Finding that want within me to make the change. Not caring what others think or say. Not needing anyone's approval but my own. I still struggle with putting my needs first, and as a mom, I think I always will but I now know what kind of woman I want to be. What people I want to surround myself with & what my goal is. For myself and only me. I truly believe in my heart that's what I must do if I'm to be successful in the long term. So for what seems like the millionth time, I started again. today.
Finding myself has been a tough journey thus far. But going down this road has helped improve so many other parts of my life that I've been sort of neglecting, for years....including friendships & my marriage. I want to be healthy....all around....mind, body & soul.
And that starts now.


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Businessman held after teen's rapeComment on this story
Johannesburg - A man was arrested for allegedly raping a 15-year-old girl in Diepkloof, Soweto, Gauteng police said on Tuesday.
The 38-year-old businessman who sells delicacies such as sheep heads, was arrested at his house in the area on Monday, Warrant Officer Kay Makhubela said.
The girl went to the man's stall and tried to buy sheep head, known as "skop".
"He then (allegedly) grabbed her, put her in his car, and took her to his house where he raped her," said Makhubela.
The girl escaped and reported the rape to police on Sunday. The man would appear in the Protea Magistrate's Court on Tuesday. - Sapa
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6 posters
5 groups
Jayne (Parker Posey) and Laura (Demi Moore) are about to take on the first man they just might not be able to handle: their seventy something—year—old father Joe (Rip Torn). Dutiful daughters returning to the house they grew up in, Jayne and Laura are forced to take a closer look at their own not—so—perfect lives while dodging childhood memories. Laura suspects that Joe needs full—time care, but Jayne refuses to believe that their father's condition is that serious. Jayne's compulsion to escape reality only increases Laura's attempts to yank her back down to earth
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A Bayesian variable selection procedure to rank overlapping gene sets
1 Department of Molecular Biology and Genetics, Aarhus University, Blichers Allé 20, PO Box 50, Aarhus, Tjele DK-8830, Denmark
2 Department of Animal Science, Ferdowsi University of Mashhad, Mashhad, 91775, Iran
BMC Bioinformatics 2012, 13:73 doi:10.1186/1471-2105-13-73Published: 3 May 2012
Genome-wide expression profiling using microarrays or sequence-based technologies allows us to identify genes and genetic pathways whose expression patterns influence complex traits. Different methods to prioritize gene sets, such as the genes in a given molecular pathway, have been described. In many cases, these methods test one gene set at a time, and therefore do not consider overlaps among the pathways. Here, we present a Bayesian variable selection method to prioritize gene sets that overcomes this limitation by considering all gene sets simultaneously. We applied Bayesian variable selection to differential expression to prioritize the molecular and genetic pathways involved in the responses to Escherichia coli infection in Danish Holstein cows.
We used a Bayesian variable selection method to prioritize Kyoto Encyclopedia of Genes and Genomes pathways. We used our data to study how the variable selection method was affected by overlaps among the pathways. In addition, we compared our approach to another that ignores the overlaps, and studied the differences in the prioritization. The variable selection method was robust to a change in prior probability and stable given a limited number of observations.
Bayesian variable selection is a useful way to prioritize gene sets while considering their overlaps. Ignoring the overlaps gives different and possibly misleading results. Additional procedures may be needed in cases of highly overlapping pathways that are hard to prioritize.


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Aberforth Geared Income Trust plc In accordance with UKLA Listing Rule 15.6.8R, the following represents the Company's investments , as at 30 June 2013, in other UK listed closed-ended investment funds (including REIT's) which themselves do not have a stated investment policy to invest no more than 15% of their gross assets in other UK listed closed-ended investment funds ( including REIT's): % of the Company's Total Assets less Name of Company Current Liabilities --------------------- ------ Hansteen Holdings plc 1.6 ------ Total 1.6 ------ The Company does not invest in any securities issued by investment trusts or investment companies with the exception of real estate investment trusts (REIT's). For further information contact: Gary Tait, Aberforth Partners LLP, telephone: 0131 220 0733. Aberforth Partners LLP, Secretaries - 1 July 2013 -0- Jul/01/2013 11:52 GMT
ABERFORTH GEARED INCOME TRUST PLC: Portfolio Update
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Protein rich rajma and chick peas tossed with roasted capsicum and Indian spices to perfection. Generously loaded with protein, fibre and other important nutrients like calcium, iron, zinc and vitamin C, this salad is an all-in-one treat for healthy skin as well as strong bones, hair and teeth.
Preparation Time: 20 mins   Cooking Time: 7 mins
Makes 6 servings
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Very easy to make and filling....protein helps to build muscle mass!!
Cook It Up With Exotic Veggies
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Facebook Hashtags: This Week in Social Media
Welcome to our weekly edition of what's hot in social media news. To help you stay up to date with social media, here are some of the news items that caught our attention.
What's New This Week?
Facebook Launches Clickable Hashtags: Clickable hashtags are rolling out on Facebook. "When you click on a hashtag in Facebook, you'll see a feed of what other people and Pages are saying about that event or topic."
Getting Started With the New Myspace: What Businesses Need to Know
If you keep up with social media news, you may be interested in the relaunch of Myspace.
Are you wondering if Myspace is a place for your business?
In this article, I will look at what types of businesses can use the new Myspace and how to create a great profile with the new layout.
Please note that the new Myspace is in beta mode—you can request an invite here or keep an eye out for invite offers from friends.
What is the New Myspace?
In case you missed it, here is the preview video of what the new Myspace has to offer.
Myspace has rebranded itself as a social entertainment network—connecting the Gen Y audience to their favorite music, celebrities, TV, movies and games.
They are also home to Myspace Music, which helps major, independent and unsigned artists reach new audiences.
Study Highlights Growing Social Media Addiction
Are you addicted to Facebook or Twitter? As social media continues to grow, details are starting to surface about people's behaviors and consumption of information in the social space.
As marketers learn more about the "how, when and where" of social users, we can better understand how to optimize our marketing efforts.
Here are two studies that drill down on "how we act" and "what we want" in the world of social networking.
#1: Are We Addicted to Social Media?
A recent independent study by Retrevo Gadgetology revealed some interesting stats about our love for social media sites. The study asked 1,000 users the "when, where and what" regarding social media sites like Twitter and Facebook. The stats suggest we just might be completely addicted to social networking (raise your hand if you tweet from the bathroom!).
5 New Studies Show Facebook a Marketing Powerhouse
When you hear that Facebook is yanking Yahoo from its ranks and inching up on Google's traffic throne, you can't help but pay attention.
And if you work for a business or own one, it's likely that social media marketing is on your radar. More and more marketing dollars are beginning to shift toward social media marketing and this trend only continues to climb.
Here are 5 studies that show how Facebook is undoubtedly a leading online social contender and a key tool that is continually changing the landscape of online engagement and fan loyalty.
Social Media Differences Among Teens, Boomers and Moms: New Study Findings
Relationship building via social media marketing is not a one-size-fits all endeavor. Moms, teens and Baby Boomers are three big social media subgroups groups that are unique.
Just like with traditional marketing, the more you know your audience, the more successful you will be at grabbing their attention and keeping it.
In terms of marketing opportunities, recent online buzz shows teens, Boomers and moms as three of the most desirable social networking groups. They are active on these sites and their behaviors have been studied closely.
Each group is unique, and the secret to success is understanding where they are spending their time and how they are using the social sites to engage and connect.
Everything You Need to Know About LinkedIn
Did you join LinkedIn because someone you know invited you and you didn't want to hurt his or her feelings, but now you're wondering why you did it?
Guess what? If you wrinkle your nose in disgust when someone mentions "social media," LinkedIn is for you!
Because LinkedIn is not like MySpace and Facebook. It's not where teenagers post pictures of their high school prom or their latest beach party.
LinkedIn was built for professionals who want to use their existing and future social networks to build a career. And for companies that want to find qualified employees. And for job-hunters.
5 Ways to Make Video a Social Experience
Video is very hot and there's a strong social media connection. Are you using video to promote your business? Do you know the best ways to leverage this growing form of content?
What follows are 5 ways you can tap into the exploding video frontier—and achieve many social media advantages.
Why Video Now?
The demand for video is already proven: U.S. audiences viewed nearly 28 billion online videos in November 2009 alone.
The demand for video in a social setting is clearly growing: Nielsen reports that online video viewing on social networking sites was up 98% in 2009.
11 Mind-Blowing Reasons Your Business Needs Facebook
Everyone seems to be using Facebook to connect with old friends, but do you realize what this huge network could mean for your business? In the past 3 years, Facebook has surged past MySpace to become our preferred online hangout. And businesses are beginning to catch on.
Interesting research shows just how influential Facebook has become in our daily lives. Combined with several critical adjustments to how Facebook publishes "news" and intersects with other sites, the state of Facebook is mind-blowing. And that's a big deal for your business.
Here are 11 vital reasons your business needs to be involved with Facebook:
Social Media Marketing: An Hour a Day
Suppose you met an experienced marketing consultant who promised to give you one-hour assignments five days a week for three months to teach you a brand-new marketing channel.
And the result was a detailed marketing plan for that channel.
Suppose the marketing channel was social media? And suppose he only charged you $30?
Would you accept his offer? I thought you might.
The consultant is Dave Evans, a communications expert who now focuses on using social media to market goods and services. His 400-page book is Social Media Marketing an Hour a Day. Here's a comprehensive review of some of the main tips from this excellent book.


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But what I hear about the role of women is often inspired by an ideology of machismo.
Murder And machismo: Women In Peril In Latin America Violence against women in Latin America has surged over the past two decades.
She talked about being a woman in a minority where "the machismo of the Sabra"—a native-born Israeli—is still supreme.
It was the age of unbridled excess, avarice, and machismo gone haywire.
Violence against women continues to plague Turkey, and a pioneering new female political party blames Erdogan's machismo.
But Castro nixed having a colostomy, perhaps out of pride, machismo, or hubris—or some combination of the three.
What it signified was obvious: the machismo inherent to youth sports that parents crave.
The smartest thing Bush does is drop the machismo that characterized so much of his term of office.
The play is about violence, machismo, poverty, desperation, and surrogate-father figures.
machismo was more meaningful to the average estate than education.
Aggressive masculinity; blatant virility: machismo, a he-man complex/ with Chicago machismo, also universal adolescent horniness
[1960s+; fr Spanish]


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Pretty Posts
As discussed earlier, Microsoft has included many new features along with variation in many features in Windows 8. One such new feature is the lock screen. For a new user the first thing to be noticed is the metro start screen and the lock screen that are quite a new features in Windows 8 than the earlier versions of OS. If your computer stays in sleep mode then you can see the lock screen on your system. You can customize the lock screen by following this tutorial.
Many users find the lock screen useful whereas some don't find it that useful. Once the computer is locked you need to dismiss the lock screen in order to log in back to Windows. The lock screen displays time, date and along with some apps and notification.
There are two major elements that make up the Windows 8 Lock Screen. Firstly, the background photo that uses upto 95% of the lock screen and secondly, are the apps that can be pinned to gain direct access. Follow the steps below to change the background image of the lock screen.
Change Background Image of the Lock Screen
- Hold Windows key + C to open Windows 8 Charm Bar while you are on desktop and then click on Settings button or else you can directly open the Charm Settings using the Windows+I hot key.
- Under the Charm Bar settings menu, click on Change PC Settings to open your device Metro Settings
- Click to open the Personalization tab and show all the customization options. There you can select the Lock screen to personalize it by adding a new picture or browse from the existing one. Make sure to select pictures of required length or else it won't appear
You can now see that the background image has been changed.
Customizing Apps that are pinned to the lock screen
Upon changing the lock screen background pictures or wallpapers, you will see the option to choose the apps that will appear on the lock screen. Simply click on the plus button to choose a new metro app to be displayed on the lock screen. You are allowed to select up to eight apps for the Windows 8 lock screen.
You can also customize the notifications area that is you can add or remove apps from it. The apps that are capable of displaying notifications only appear here. These apps notification can be viewed even if the lock screen is enabled.
You can also use the freeware application named LockPic, which allows you to customize and change the lock screen wallpaper or background from a collection of more than 1000 wallpapers in Windows 8.
Following the steps discussed above you can customize the all-new lock screen on Windows 8. The Lock screen concept is useless for desktops and laptops whereas it makes sense for users having windows 8 operating tablet so, you can disable the lock screen on your desktop.


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Sheryl Crow Style on Cougar Town
Cougar Town Style: Sara
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In this week's episode of Cougar Town, Sheryl Crow makes an appearance as Grayson's new girlfriend Sara. Here she looks effortlessly cool in her J Brand cropped cargos, black top, and leather ankle boots, topping things off with a more feminine beaded necklace and a zipper detailed hobo bag. Get her exact pants and other similar pieces now!
Photo Copyright 2010 ABC, Inc.


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Most reviews were positive. How is medication working now? We started our almost eight year old who has mild Asperger's with ADHD on 0.1 last week in conjunction with 20 mg. of Daytrana. Don't see any significant difference yet but will begin 0.1 twice a day today. The initial dose doesn't seem to make him sleepy at all! Also, is anyone monitoring blood pressure regularly? Thanks.
Any updates on children who started Kapvay in February and March?
- Posted:
- 22 Apr 2011 by lovemj
- Topics:
- daytrana, attention deficit hyperactivity disorder (adhd), asperger syndrome, kapvay
Responses (1)
28 Mar 2012
Hello lovemj. No one ever responded to your question and thats Unfortunate. I study the various disorders and I am more curious than ever to find out how is your son doing? The combination of the two drugs, is he still taking them and if so, has the dose increased, or adjusted in any way? I hope hes doing well and the best of wishes to you and your family. Regards, pledge
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My 9 yr olds dr just switched him from clonidine to kapvay, and he won't go to sleep now???
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Also are moody & oppositional behaviors common in the first 2 weeks because of the tiredness it causes?
1 answer • 16 Sep 2014


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Sandbox: Characters The Bible
We don't have an article named Sandbox/CharactersTheBible. If you want to start this new page, just click the edit button above. Be careful, though, the only things that go in the Main namespace are tropes. Don't put in redirects for shows, books, etc.. Use the right namespace for those.


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Iran's Navy establishing base near Pakistan border: Cmdr.
The naval base, which is under construction, is situated in the Gwatr Gulf on our country's farthest eastern shores bordering Pakistan." Iran's Navy Commander Rear Admiral Habibollah SayyariIran's Navy Commander Rear Admiral Habibollah Sayyari says the country is establishing a new base in the Sea of Oman near Pakistan's border to boost the Islamic Republic's defense capabilities. "The naval base, which is under construction, is situated in the Gwatr Gulf on our country's farthest eastern shores bordering Pakistan," Sayyari said on Sunday.
"The Iranian navy has so far had no military presence in the area, but now, we will be present in the region to defend the interests and maritime resources of our country and exercise a tighter control over the traffic in the region," Sayyari noted.Iran's Navy has been seeking to increase its naval presence in international waters, as well. Iran's Navy has also held several military maneuvers in order to display the country's capabilities in defending its maritime borders. The Islamic Republic has repeatedly assured other nations, especially its neighbors, that its military might poses no threat to other countries, insisting that its defense doctrine is based on deterrence. YH/HMV/HJL


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The Lofts at Worthington486 Royer Dr., Lancaster, PA 17601
- $909 - $1,544
- 1 - 2 Beds
Note : Prices & Availability Subject To Change
Note : Prices & Availability Subject To Change
The Lofts at Worthington is located on the Oregon Pike in beautiful Manheim Township! Be among the first to call this luxury planned community your home. Enjoy a secured building with elevator access, granite countertops and a full suite of appliances. Experience convenience just outside your front door with restaurants, banking, salons and much more right in your community. 1 and 2 bedroom and loft apartments available. Please call today for your tour of this exciting new community!
The Lofts at Worthington is located in Lancaster, PA in the 17601 zip code. View this apartment on a map.
Professionally Managed By: Worthington Commercial LLC
Community Features
- Loft Apartments with Dramatic Cathedral Ceilings
- Convenient Elevator Access
- Secured Entrance
- Solid Wood Cabinets
- Granite Countertops
- Gourmet Kitchens with Gas Cooking
- Washer/Dryer in Every Home
- Spacious Closets
- High Efficiency Gas Heat
- On-Site Restaurants, Banking, and More
- Extensive Walking, Hiking, and Biking Trails
- Grill & Chill Recreational Area
- Spectacular Outdoor Fountain
- Planned Community in Desirable Manheim Township
*Note: In Select Units
Pet Policies
Pets Welcome Fees and Restrictions Apply
Dog: Up to 2 are permitted
- 25lb Weight Limit.
- 2 Pet Maximum $500 non-refundable pet deposit fee per pet and monthly fee of $75 per pet.
- Deposit: $500.00 Fee: $75.00
Cat: Up to 2 are permitted
- 2 Pet Maximum-$500 non-refundable pet deposit fee per pet $50 Monthly Fee per pet.
- Weight: 25lbs
- Deposit: $500.00 Fee: $50.00


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The newly-released statement reads, in part, "With over a century of combined experience as wholesalers of precious metals, the friendly representatives and executives at Goldco Direct have recently opened a public sales office at 19528 Ventura Blvd #370 Tarzana, CA 91356. With this recent expansion, we will bring the knowledge and expertise of a large-volume wholesale dealer directly to individual investors."
The company statement explains that, because of the current economic crisis, all paper (fiat) investments are exposed to the risks of fickle, unstable governments and unpredictable environmental, monetary, and political conditions. In Goldco's professional opinion, "It is crucial to diversify investment portfolios to include historically-
The statement goes on to say "Goldco Direct agents understand the real value of tangible assets and are experienced in all facets of the precious metals industry." The company's expertise as a large-volume wholesaler allows it to offer insight and a level of service unmatched in the precious metals industry.
Goldco Direct offers two primary services: delivering precious metals to clients' homes (upon request); and, helping clients add precious metals to IRA's and 401k's as a tool to diversify retirement portfolios and preserve individual wealth.
President Gerszt says, "We're here to help investors protect and grow their hard-earned assets to ensure their financial stability—in good times and bad. We need to make sure they're informed about the financial decisions they're making and we are here to make sure they are."
# # #
Goldco Direct is a precious metals insights and procurement company located in Tarzana, California dedicated to helping investors diversify, protect, and grow their finances in good times and bad. For more information, contact Trevor Gerszt at (855) 848-GOLD (4653) or visit the company website at www.GoldcoDirect.com


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Islamic International Undergraduate Scholarships
Even though Islam is the second largest religion in the world, many Muslims live in countries where opportunities are as readily available as in the United States. While many Muslims aspire for further education to help themselves and their family, the opportunity may not exist for financial reasons. However, there are a number of international scholarships available, some available specifically for those in developing countries.
Aga Khan Foundation
A limited number of scholarships are available through the Aga Khan Foundation, aimed at those students who are in developing countries and with limited financial means. Scholarships are available each year and available on a 50/50 split between grant and loan. Applications are available on the first day of each year and scholarships are awarded to those with strong academic records, financial need, admission to an educational institution and a thought-out career plan.
Oxford Centre for Islamic Studies
A scholarship program given to students of developing countries, the Oxford Centre for Islamic Studies, a branch of Oxford University in England, offers financial assistance to those attending Oxford. Applicants must show that their course of study is relevant to the Muslim world. Scholarships can be renewed based on satisfactory academic progress. The scholarship covers the entire cost of fees associated with attending the university.
Central Bank of Malaysia
The Central Bank of Malaysia (Bank Negara Malaysia) established the Fund for Shariah Scholars in Islamic Finance in June 2005 to encourage the advancement of the Islamic Finance Industry. The scholarships are available to those in master's or doctorate studies at post-secondary institutions in the field of Shariah or those part of the Certified Islamic Finance Professional program from the International Centre for Education is Islamic Finance.
Islamic Development Bank
Three scholarships are available through the Islamic Development Bank, though only one is available to those living in non-member countries (the United States is not a member country). The Scholarship Programme for Muslim Communities in Non-Member Countries provides scholarships to those who have academic merit, and a financial need. The M.Sc. Scholarship Programme is for those in least-developed member countries and available to those studying in certain subjects, including science, engineering and technology. The Merit Scholarship Programme for High Technology is for those in three-year Ph.D. programs and six to 12 months of post-doctoral research.
- Aga Khan Foundation: International Scholarship Programme
- University of Oxford: Oxford Centre for Islamic Studies Scholarships
- Central Bank of Malaysia: Shariah Scholarship Award
- Islamic Development Bank: Scholarship Programme for Muslim Communities in Non-Member Countries
- Islamic Development Bank:M.Sc. Scholarship Programme
- Islamic Development Bank: Merit Scholarship Programme for High Technology
- Photo Credit graduation image by timur1970 from Fotolia.com
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The organization is not a charity. Iana Financial 9334 176 Ave. Edmonton ... College Grants for Muslims; Muslim Scholarship Facts; Islamic Educational...


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- Filed Under
Barb Foreman doesn't know where the time went.
During Friday's Division III district final softball game between Bucyrus and New London, she cheered on the Redmen while her husband, Bob, the team's scorekeeper, kept stats in the dugout.
It was just like any other Bucyrus game the couple has attended throughout the years, with one special exception. The Foremans were celebrating their 50th wedding anniversary. ...


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No Witch
Sounds Like: Seattleites who formed after Pretty Girls Make Graves split, sound nothing like PGMG. They've chosen the folksy, countrified movement to dominate.
Free Association: Capitalizing on the bearded workerwear moment better than anyone.
For Fans Of: Fleet Foxes, Beirut x Silver Jews, gritty Pacific NW soulfulness.
DJ Vadim presents The Electric
Life Is Moving
(Organically Grown Sounds)
Sounds Like: Russia's premier turntablist (there aren't many) recruits a soulful U.K. songstress and an emcee for a slick and funky package of low-key, chill hip-hop.
Free Association: S'like Lucy Pearl if Saadiq
rapped and Ali Shaheed was more DJ Shadowy.
For Fans Of: Herbaliser, Roots Manuva + Aaliyah,ambient hip-hop.
(Modular Recordings)
Sounds Like: The Aussie quartet's third is already a sensation of disco- inspired electro dance music right on trend and perfect for spring-hungry dancing hipsters.
Free Association: Now carrying the dance torch handed off by LCD Soundsystem.
For Fans Of: Daft Punk x Caribou, Air + Erasure,ecstatic late-night freakouts.
My Morning Jacket's Patrick Hallahan talks music, Philly and his brand-new restaurant
The top 10 shows around Philly this week
The top 10 shows around Philly this week
G. Love's new genre-bending LP is a keeper
The top 10 shows around Philly this week
The top 10 shows around Philly this week
The top 10 shows around Philly this week


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Women's Basketball Falls to Wake Forest, 76-50
Dec. 21, 2004
The Greyhounds got within two points of Wake Forest early in the second half but a 13-0 run gave the Demon Deacons the edge in a 76-50 final on Tuesday afternoon at Lawrence Joel Memorial Coliseum. Loyola falls to 2-7 with the loss while Wake improves to 9-1.
In the first half, Wake Forest jumped out to a 7-0 lead before Jackie Valderas gave Loyola its first basket at 15:47 for a 7-2 score. Wake's Liz Strunk then went on an 8-0 run with two three-point baskets and a layup for a 15-2 Demon Deacons lead. Ebony Toliver ended that run with a basket at 13:40.
With the score set at 19-6, Lauren Troupe tried to give the Greyhounds some momentum with a three-point basket at 10:22 but Cotelia Bond-Young and Jennifer Johnson of Wake Forest stopped that momentum with three-pointers of their own for a 25-9 score with 9:36 remaining. On their next trip down the floor, Katie Scherle gave the Greyhounds a three-point play at 9:27 for a 25-12 score.
Both teams went without a basket for the next several minutes before Bond-Young tallied her second three of the game at 6:38 to put Wake up 28-13. The Greyhounds did well to delete that deficit over the next several minutes by going on an 8-0 run to cut the lead to 28-21 with 2:52 left in the half.
Johnson ended the Demon Deacons almost four minute scoring drought at 2:31 and was followed by a three-point basket by Erin Farell for a 33-21 score with just under two minutes remaining. But Loyola's defense did not allow another Wake basket for the remainder of the half as they went on a 6-0 run as the clock ran down for a much slimmer 33-27 Wake Forest lead.
In the start of the second half, the Greyhounds went on a 5-0 run to get within two of the Demon Deacons, 34-32 but after exchanging baskets, Bond-Young hit her third of four three-point baskets to begin a 13-0 run. Wake led 49-34 at the close of that run at 11:54 and Loyola never got any closer.
Loyola was led by Jackie Valderas with 10 points. She was followed by Ebony Toliver and Lauren Troupe with eight points each. Troupe led the game in rebounds with 12.
Bond-Young led four Demon Deacon players in double-figures with 22 points. She was followed by Strunk with 19, Johnson with 15 and Farell with 13.
The Greyhounds outrebounded Wake Forest 44-37 while the Demon Deacons held the advantage in shooting (39.7%-30.9%).
Loyola is back in action at Reitz Arena after the holiday, hosting Long Island University on December 30 and Liberty on January 4.
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The Loyola University Maryland women's basketball fell to Villanova University, 67-55,...
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Senior Colleen Marshall was named to the Preseason All-Patriot League Team and the Loyola...
Saturday, Nov 28 EVENT LOCATION TIME COVERAGE Columbia New York, N.Y. L, 63-53 Live Stats Video
Wednesday, Dec 2 EVENT LOCATION TIME COVERAGE Old Dominion Norfolk, Va. 11:00 AM Live Stats Video
Saturday, Dec 5 EVENT LOCATION TIME COVERAGE Mount St. Mary's Emmitsburg, Md. 4:30 PM Live Stats Video
Tuesday, Dec 8 EVENT LOCATION TIME COVERAGE Maryland College Park, Md. 7:00 PM Sunday, Dec 20 EVENT LOCATION TIME COVERAGE UMBC Reitz Arena 12:00 PM Video Tuesday, Dec 22 EVENT LOCATION TIME COVERAGE St. Francis Brooklyn Brooklyn, N.Y. 1:00 PM
Team Information• Roster
History & Records
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Some people believe Richie Incognito deserves a second chance
Once a social pariah, it seems people's hatred of the offensive lineman has cooled as of late.
Remember when Richie Incognito was the worst person on the planet? A man so vile, so hated, that there was no way he would ever work in this country again. Forget having friends. Forget having a life. He's done. Sayonara.
Well, it seems that more than a few people's emotions have cooled since his bullying scandal with the Miami Dolphins that involved former teammate Jonathan Martin. Incognito was brought in by the Tampa Bay Buccaneers for an interview on Monday. But this is beyond just NFL personnel. The Newark Star-Ledger conducted a poll on its website, asking Giants fans if the team should sign Incognito. The results were very telling.
A wide margin -- a little more than 70 percent -- feels the team should indeed bring in Incognito to aid their moth-eaten offensive line. Here's what one reader named "TR150" had to say.
"I feel dirty for saying this, but how about a look at Richie Incognito? Heck with teams captains. Bring in someone who can keep the Q b clean. At this point, it's not about Eli or Nassib. They're both gonna get killed behind that line against premiere rushers. Heck, pass rushers period."
Another reader, named "GHOSTFACZ STARKS," offered this up:
"I think JR. should bring this Guy in... Tha G-MEN needs NASTY o-lineman. That has a mean streak... From wut I've been seeING BIG guys on ROLLER SKATES. ALL PRE SEASON.
Now, it's hard to really get a grasp on what Mr. Starks is talking about, but it's clear that he or she feels that Mr. Incognito would add a measure of toughness to a Giants offensive line that has been getting beat up all preseason. It's hard to argue with that.
But don't think this reponse is just limited to Giants fans. The Kansas City Star asked Chiefs fans is the team should try and sign Richie to a deal. The results? Well, 33 percent of respondents said the Chiefs should absolutely sign Incognito, while 39 percent said the Chiefs should try and sign him with a character clause in his contract. The people against the signing? They just clock in at 28 percent.
Well, maybe it goes to show that a little time -- and many more egregious events happening in society -- can make people forget about certain misdeeds.


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Kaedah penyelesaian permasalahan dalam teknologi reality maya masa kini menggunakan enjin permainan komputer 3D
Shiratuddin, M.F., Yaakub, A.R. and Zulkifli, A.N. (2001) Kaedah penyelesaian permasalahan dalam teknologi reality maya masa kini menggunakan enjin permainan komputer 3D. Jurnal Analisis, 8 (1&2). pp. 153-164.
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Before the 1990's Virtual Reality (VR)applications were limited to activities that were carried out by big-budgeted giant companies and the militaries. VR technologies such as VRML and Panoramic Imaging enable computer users to use VR applications either freely or at a very minimal cost. However,the two mentioned above have their own limitations. This paper discusses several issues pertaining to the limitations and proposes a method that can be used as an alternative in realizing VR application to be disseminated to all computer users. The method involves the use of a 30 computer game engine that exists in the First Person Shooter (FPS) computer game.
|Publication Type:
|Journal Article
|Universiti Utara Malaysia Press
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Citizen Kane (Digibook) Blu-ray
Our Price $24.99
List Price $34.99
Your Savings $10.00 29%
5.05.0(2 reviews)See all 2 reviewsWrite a Review
Orson Welles' masterwork (#1 in the American Film Institute's list of Best American Movies) dazzles anew in a superb 70th-anniversary digital transfer. It's grand entertainment, sharply acted (starting many of Welles' Mercury Players on the road to thriving film careers) and directed with inspired visual flair. Chronicling the stormy life of an influential publishing tycoon, this Best Original Screenplay Academy Award winner (1941) is rooted in themes of power, corruption, vanity - the American Dream lost in the mystery of a dying man's last word: "Rosebud."
Additional Details
DirectorOrson Welles
Primary CastOrson Welles Joseph Cotten Ruth Warrick More
Production Year1941
Technical Specs
- Format: Blu-ray
- Rating: PG
- Number of Discs: 2
- Run Time: 119 Minutes
- Region: A
- Aspect Ratio: Fullscreen
- Language: English
- Studio: Warner Home Video
- Blu-Ray Release Date: January 17, 2012
- Packaging: Custom Case
- Subtitles: English, Spanish, French
- Audio: ENGLISH: DTS-HD MA Mono
- Color: Black & White
Disc 1 (Blu-ray):
Separate Commentaries by Roger Ebert and Peter Bogdanovich
Interviews with Ruth Warrick and Robert Wise
Premiere Newsreel
Stills Gallery
Disc 2 (DVD):
The Battle Over Citizen Kane - The 1995 Best Documentary Feature Oscar Nominee
Reviewed by 2 customers
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- Engaging Characters
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Comments about this product:
One of the greatest films ever made.
- Engaging Characters
- Entertaining
- Great Cinematography
- High Production Value
- Informative
- Original
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- Adult Viewers
- At Home
- Perfect Gift
- Younger Viewers
Comments about this product:
Orson Well's life was virtually destroyed by the production of this "iconic" film. As it is similar to the life of multi-millionaire William Randolph Hurst, who was personally responsible for Wells's troubles.
With that being said, this movies is dubbed "The Greatest Movie Ever". This is my absolute favorite movie of all time.
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- Filed Under
I was on an NJ Transit train the other day and noticed a mother and three children sitting across from me, each with a suitcase at their feet.
They got off at the Newark Airport stop in a flurry. Coats on, cellphones tucked away, suitcases lugged down the aisle. They were chatting happily.
They left and the doors closed. It was then I noticed a pair of fuzzy pink mittens on the seat. The littlest girl had left them. ...


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Posted in freebies, goodreads, story Tags: DRitC, freebies, GoodReads, HSD, I Am The Highway, Jason Huffman-Black, link
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The Top 10 In Action Sports
01Kenton Cool And The Legend Of Everest
02The Martyn Ashton Interview: Meet the Man Who Got Back on the Bike
03Legends Behind the Lens: The Dan Milner Interview
04We Asked Surf Star Coco Ho For Her Step-by-Step Guide to the Basics
05The Tony Hawk Interview: How Is The Birdman Still Flying High After All These Years?
06We Toured Britain's Action Sports Hotspots With The New Ford S-MAX
07The Legend Of El Dorado: One Man's Obsession With Finding A City Made Of Gold
08I Am Legend: How Audiences – Real Or GoPro'ed – Can Affect Your Mind And Performance
09Watch A Freerunning King Defy The Laws Of Gravity In This Urban Assault On London
10Living On The Blood and Urine of Dead Sea Turtles: The Shocking Story of A Sailor Stuck in Hell
Videograss Saturdays - Jed Anderson vs LNP
A Snowboarding video by onboard - 10,817 views
The VG crew headed to Anchorage Alaska for the last rail trip of the year. This was Laurent's first and only trip of the season after breaking his back in December. Regardless of a busted spine, Laurent and Jed went head to head in a battle royale on Gus Engle's ever famous backyard baby box. Place your bets and peep this quick PIG session. OINK!


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A big step forward for both companies
Buy what you already own
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Western Asset Worldwide Income Fund Inc. (
) will begin trading ex-dividend on January 16, 2013. A cash
dividend payment of $0.084 per share is scheduled to be paid on
January 25, 2013. Shareholders who purchased SBW stock prior to the
ex-dividend date are eligible for the cash dividend payment. This
marks the 9th quarter that SBW has paid the same dividend. At the
current stock price of $15.55, the dividend yield is 6.48%.
The previous trading day's last sale of SBW was $15.55,
representing a -6.27% decrease from the 52 week high of $16.59 and
a 15.1% increase over the 52 week low of $13.51.
For more information on the declaration, record and payment
dates, visit the
Dividend History
The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.
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November 27, 2015
Mexican prosecutors say they broke up not one, but two Indiana Jones-style plots to "extract" the son of late Libyan dictator Moammar Gadhafi from Libya as his father's regime crumbled.
Assistant Attorney General Jose Cuitlahuac Salinas says the plan to bring al-Saadi Gadhafi to Mexico involved piles of stolen passports, white-knuckle flights with pilots who refused to land in war-torn Libya and luxury homes bought under false names in Mexico.
Salinas said Wednesday the ring involved a Canadian woman, a Danish man and two Mexican suspects charged with attempted immigrant trafficking, falsifying documents and organized crime.
Salinas says the ring hired pilots to fly from Mexico to Kosovo, Tunis and on to Libya.
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|ISSN 1088-6850(online) ISSN 0002-9947(print)
Cell-like 0-dimensional decompositions of
Abstract | References | Similar Articles | Additional Information
Abstract: Let G be a cell-like, 0-dimensional upper semicontinuous decomposition of . It is shown that if is a tame 1-complex which is a relatively closed subset of a saturated open set U whose boundary misses the nondegenerate elements of G, then there is a homeomorphism so that and misses the nondegenerate elements of G. This theorem implies a disjoint disk type criterion for shrinkability of G. This criterion in turn provides a direct proof of the recent result of Starbird and Woodruff that if G is an u.s.c. decomposition of into points and countably many cellular, tamely embedded polyhedra, then is homeomorphic to .
Retrieve articles in Transactions of the American Mathematical Society with MSC: 57N12
Retrieve articles in all journals with MSC: 57N12
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This Website has Expired
Kona Oceanfront Home for sale
Prime location, beautifully remodeled interior, gated community, and built-in up-keep make this the perfect, no-hassle solution to oceanfront living. The award-winning floorplan features two en suite bedrooms plus a den that functions as a third bedroom. This oceanfront retreat comes turnkey furnished, ready for you to move in and enjoy, or continue using as a successful vacation rental. Don't miss this rare opportunity.


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A whole new slew of casting rumors have popped up for Captain America: The Winter Soldier. First up is Mary Elizabeth Winstead. You may know her…More
Tagged: sequel
Incredible Hulk 2? Not Any Time Soon1
If you were looking forward to seeing a sequel to the Edward Norton reboot of The Incredible Hulk you may be waiting for a little…More


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Biophan Receives $5 Million Credit Facility Bridging to $30 Million SBI Financing; Biomed Sells Shares to Provide Interim Funding; Biophan CEO Weiner Files Related Form 4
The facility from Biomed will give Biophan access of up to $1.5 million per month as needed. The Biomed facility will bear interest at the rate of 8% per annum and is convertible into shares of Biophan common stock at Biomed's election at a 15% discount to last Friday's market closing price. In addition, Biomed will receive warrants for the purchase of 1,198,630 shares of Biophan common stock at an exercise price that is a 10% premium over last Friday's market closing price. To acquire the capital to supply the credit facility, Biomed sold 4 million shares of Biophan common stock and 1.18 million Biophan warrants in a private transaction. Because under SEC regulations, beneficial ownership of Biomed's assets is attributed to Mr. Weiner, he has reported the transactions on a Form 4 filed today with the SEC.
"Biomed stands behind Biophan and is willing to sell some of its holdings in order to provide Biophan with interim financing so Biophan's momentum is undeterred. Weiner continued"
"The $5 million credit facility is convertible and carries warrants, allowing Biomed to continue to be a long term investor in Biophan," said Michael Weiner. "Biomed stands behind Biophan and is willing to sell some of its holdings in order to provide Biophan with interim financing so Biophan's momentum is undeterred. Weiner continued, "Overall, this credit facility is a very positive endorsement of our belief in Biophan's long-term potential."
About Biophan Technologies
Biophan develops and markets cutting-edge technologies designed to make biomedical devices safe and image compatible with the magnetic resonance imaging (MRI) environment. The Company develops technologies that enable medical systems such as pacemakers, interventional surgical devices such as catheters and guidewires, and implants such as stents to be safely and/or effectively imaged under MRI. Biophan is developing these same technologies to provide new MRI contrast agents. Other applications include drug delivery and power systems which derive energy from body heat. Biophan also has an equity position in MYOTECH, LLC to assist in development and commercialization of an MRI compatible cardiac assist device - the MYO-VAD(TM). Committed to growth through innovation and developmental leadership, Biophan and its licensors now hold a total of 157 U.S. patents, licenses, or applications, plus international applications. This total includes 48 issued U.S. patents, 7 recently-allowed applications that will issue as patents in the near future, and 102 pending applications at various stages of examination at the U.S. Patent and Trademark Office. The patents cover areas including nanotechnology (nanomagnetic particle coatings), medical device designs, radio frequency filters, polymer composites, thermoelectric materials which generate electricity from body heat, and photonics. Biophan has joint development and licensing agreements with Boston Scientific and NASA's Ames Center for Nanotechnology. Biophan's goal is to make all biomedical devices capable of safely and successfully working with MRI, and delivering other technologies which will improve quality of life. Biophan is also listed on the Frankfurt Stock Exchange under the ticker symbol BTN. For more information, please visit www.biophan.com.
Cautionary Statement Regarding Forward-Looking Statements
Certain statements included in this press release may constitute forward-looking statements within the meaning of applicable securities laws. These statements reflect what Biophan anticipates, expects, or believes may happen in the future. Biophan's actual results could differ materially from the outcome or circumstance expressed or implied by such forward-looking statements as a result of a variety of factors including, but not limited to: Biophan's ability to develop its technologies; the approval of Biophan's patent applications; the successful implementation of Biophan's research and development programs; the ability of Biophan to demonstrate the effectiveness of its technology; the acceptance by the market of Biophan's technology and products incorporating such technology, the ability of Biophan to effectively negotiate and enter into contracts with medical device manufacturers for the licensing of Biophan's technology; competition; the ability of Biophan to raise capital to fund its operating and research and development activities until it generates revenues sufficient to do so; and the timing of projects and trends in future operating performance, as well as other factors expressed from time to time in Biophan's periodic filings with the Securities and Exchange Commission (the "SEC"). As a result, this press release should be read in conjunction with Biophan's periodic filings with the SEC which are incorporated herein by reference. The forward-looking statements contained herein are made only as of the date of this press release, and Biophan undertakes no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances.


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If you mean the issues I've heard of regarding people getting spoiled/leaky developer parts in new Digibase kits, then no. I've always ordered my kits from Freestyle and I've never run into a problem. Your mileage may of course vary.
My one caveat about the "mini" kit is that it makes a lesser volume of stabilizer, so you may have to roll your tank instead of inverting it to ensure proper coverage of the film. And of course, with any kit, the reuse schedule of the various chemicals varies widely, so be conscientious of that.


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1I exalt You, my Elohim, O Sovereign; And bless Your Name forever and ever.
2All day long I bless You, And praise Your Name forever and ever.
3Great is יהוה, and greatly to be praised; And His greatness is unsearchable.
4Generation after generation praise Your works, And they declare Your mighty acts.
5I declare the esteemed splendour of Your excellency, And the matters of Your wondrous works.
6And they speak of the might of Your awesome acts, And I recount Your greatness.
7They send forth the remembrance of Your great goodness, And they sing of Your righteousness.
8יהוה shows favour and is compassionate, Patient and great in kindness.
9יהוה is good to all, And He has compassion on all His works.
10All Your works give thanks to You, O יהוה, And Your kind ones bless You.
11They speak of the esteem of Your reign, And talk of Your might,
12To make known to the sons of men His mighty acts, And the esteemed splendour of His reign.
13Your reign is an everlasting reign, And Your rule is throughout all generations.
14יהוה is supporting all who are falling, And raising up all who are bowed down.
15The eyes of all look to You expectantly, And You are giving them their food in its season,
16Opening Your hand and satisfying The desire of all that live.
17יהוה is righteous in all His ways, And kind in all His works.
18יהוה is near to all who call upon Him, To all who call upon Him in truth.
19He does the desire of those who fear Him; And He hears their cry and saves them.
20יהוה preserves all those loving Him, But all the wrong ones He destroys.
21My mouth speaks the praise of יהוה, And let all flesh bless His set-apart Name, Forever and ever.
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The following post is shared by Jessica Stellato, Lower Elementary Lead in the Galaxy Room at Montessori Academy at Sharon Springs in Cumming, Georgia. In this series, Jessica explores common Montessori classroom terminology.
Shortly after enrolling in a Montessori program, you will hear words like "work." Someone not familiar with this lexicon may view the word "work" as having a negative connotation, but in the Montessori environment "work" means children learning through purposeful activity. To help parents better understand what's being ...Read More →


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|Key Info
Il rifugio dei Cesari.
This is a very modern and comfortable Villa located on an elevated plot overviewing the 18th hole at Atalaya Golf and country club.
Within 5 minutes driving, we have the best beach clubs, Puerto Banus and at least 15 golf courses.
This year the villa has been recently totally renovated and offers all the amenities available in a very luxury house.
- Fully professional kitchen
- Spa with Jacuzzi, Turkish bath, gym and massage and relaxing area with Hammock
- Pool with shower and bar
- High tech amenities like Bang & Olufsen sound system, home theater, 6 smart TV 3D Wi-Fi connected.
- Wi-Fi router in each room and garden
- Italian modern design and high quality furniture
Large parking area with roof.
Fully professional kitchen:
- Kitchenaid stand mixer
- Electric oven
- Vitroceramic induction hob
- High-power extractor
- Deep fryer
- Professional dishwasher
- Paella-making kit
- Grill
- Mixer and spinner for fruit, vegetables and meals for baby.
Tableware and service amenities and tools:
- Wine decanter
- Zafferano crystal glasses
- Villeroy & Bosh flatware
- Villeroy & Bosh plates
- Table cloths
- Wine cellar
- Ice bucket
- Jamonero (Jamon de bellota holder)
- Shaker, mixer and blender and all other bartender tools
- Room service tools
We offer, available on demand, a full staff of professionals.
The villa can be transformed in your personal and private hotel with personal chef, barman, waiter and housemaid. These services are available permanently during the whole stay or on demand for any specific moment.
The price includes:
- A welcome dinner at the arrival day; foods and beverages excluded (minimum stay one week).
- A welcome courtesy kit including the basic ingredients (sugar, milk, 10 nespresso capsules, the, water, fruits and refreshing drinks) in the kitchen fridge and in the minibar (each bedroom has its own but also a safe and a nespresso machine).
- Personal chef and waiter availability up to your convenience for two dinners (minimum stay one week). The staff service comes with Villeroy Bosh tableware.
- Daily house cleaning for 3 hours at your convenience time of the day.
We are in the middle of the golf valley. La Quinta, Aloha, Atalaya, El Paraiso, Marbella golf, Guadalmina, Los Naranjos, Los Almendros and many other.
Puerto Banus is within 3/4 minutes driving like many discothèques and the best beach club.
Many historical cities like Ronda, Sevilla, Gibrarltar and Granada within 30 mins to 2 hours driving.
|Sleeps up to 11, 4 bedrooms
|4 bedrooms, 5 bathrooms of which 1 Family bathrooms and 4 En suites, Solarium or roof terrace
|Will consider
|Corporate bookings, Long term lets (over 1 month)
|Family friendly
|Great for children of all ages
|Some pets are welcome - please contact the owner, No smoking at this property
|Jacuzzi or hot tub, Sauna, Log fire, Internet access, DVD player, Sea view
|Private outdoor pool (unheated)
|Central heating, Air conditioning, TV, Video player, CD player, Telephone, Fax machine, Pool or snooker table, Games room, Safe, Satellite TV, Wi-Fi available
|Kettle, Toaster, Iron, Hair dryer
|Clothes dryer, Dishwasher, Cooker, Microwave, Fridge, Freezer, Washing machine
|1 Sofa beds, Double beds (2), Single beds (6), Dining seats for 12, Lounge seats for 12
|Linen provided, Towels provided, High chair
|Private outdoor pool (unheated), Balcony or terrace, Private garden, BBQ
|Parking, Not suitable for wheelchair users


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Hi Guys!
I'm new here and im pretty noob in using Linux. first of all, im sorry for my english grammar..
i'd like to learn everything in linux. since the vista is release, im starting to HATE windows distributions. Now, im decided to study linux starting in DSL. Small is beautiful! Hehe!
can you teach me how to dual boot DSL to Wndows XP?
thanks in advanced! :)


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Warkworth, Northumberland GenealogyEdit This Page
From FamilySearch Wiki
England Northumberland Northumberland Parishes
Guide to Warkworth, Northumberland ancestry, family history, and genealogy: parish registers, transcripts, census records, birth records, marriage records, and death records.
|Warkworth, Northumberland
Warkworth Northumberland St Lawrence
|Ancient Parish
|Civil Jurisdictions
|Coquetdale; Morpeth
|Poor Law Union
|Registration District
|Alnwick; Morpeth
|Records begin
|Parish registers: 1676
|Bishop's Transcripts: 1760
|Ecclesiastical Jurisdictions
|Rural Deanery
|Legal Jurisdictions
|Probate Court
|Court of the Bishop of Durham (Episcopal Consistory)
|Location of Archive
|Northumberland Record Office
Parish History
WARKWORTH (St. Lawrence), an ancient borough and a parish, in the union of Alnwick, partly in the E. division of Coquetdale, and partly in the E. division of Morpeth, ward, N. division of Northumberland, 7 miles (S. E.) from Alnwick. The parish comprises the townships of Amble, Acklington, Acklington-Park, Birling, Brotherwick, Bullock's-Hall, High and Low Buston, East and West Chevington. There are places of worship for Wesleyans and Scottish Seceders.[1]
Civil Registration
Birth, marriages and deaths were kept by the government, from July 1837 to the present day. The civil registration article tells more about these records. There are several Internet sites with name lists or indexes. A popular site is FreeBMD.
Church Records
Warkworth, Northumberland Genealogy parish registers of christenings, marriages and burials are available online for the following years:
|PALL = Pallot's Marriage Index (Ancestry) - (£)[2]
|WARKWORTH PARISH Online Records
Durham University Library Archives and Special Collections DDR/EA/PBT/2/262 1760-1844 Parish Register transcripts are available to search free online at FamilySearch Historical Records.
The dates of the post-1760 transcripts have been noted in detail and sometimes only cover years. For most parishes in the collection there are gaps in the sequence of transcripts. It is advisable to consult the original parish registers for these years and events.
Warkworth, St Laurence: Records of baptisms 1690-1972, marriages 1687-1974 and burials 1676-1927 are available at Northumberland Collections Service. The International Genealogical Index (I.G.I.) includes baptisms 1677-1812 and marriages 1685-1812 for this parish, and Boyd's Marriage Index includes marriages 1677-1812. Transcripts of baptisms 1690-1812, marriages 1686-1812, burials 1677-1812 and baptisms of nonconformists 1723-1824 are available in the Local Studies Departments of Newcastle Central Library and Gateshead Central Library. A transcript of monumental inscriptions at Warkworth Church & churchyard (microfiche TN95) is published by Northumberland and Durham Family History Society and these records are also available in book form at Newcastle Central Library, Local Studies Department.
FamilySearch Historical Records includes England, Durham Diocese, Marriage Bonds and Allegations (FamilySearch Historical Records)
Census records
Census records from 1841 to 1911 are available online. For access, see England Census Records and Indexes Online. Census records from 1841 to 1891 are also available on film through a Family History Center or at the Family History Library. The first film number is 438893.
Poor Law Unions
Alnwick Poor Law Union, Northumberland
Probate records
Records of wills, administrations, inventories, indexes, etc. were filed by the court with jurisdiction over this parish. Go to Northumberland Probate Records to find the name of the court having primary jurisdiction. Scroll down in the article to the section Court Jurisdictions by Parish.
Maps and Gazetteers
Maps are a visual look at the locations in England. Gazetteers contain brief summaries about a place.
Web sites
- ↑ Lewis, Samuel A., A Topographical Dictionary of England, (1848. Adapted. Date accessed: 13 August 2013.
- ↑ Pallot's Marriage and Birth Indexes, Guide to Parishes. Digital version at FamilySearch Books Online.
Need wiki, indexing, or website help? Contact our product teams.
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- This page was last modified on 18 May 2015, at 15:59.
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text:
DGT designs, develops, manufactures and globally distributes a wide range of digital game timers, electronic chess boards, chess computers and other games accessories.
DGT supplies quality products but also offers quality customer service and technical support. For product information please see this section or contact our support desk.
Read the latest news about DGT product releases, software updates, trade shows and other activities.
October 02, 2015 by Digital Game Technology
The DGT 1001 is a universal game timer suitable for school, club or home use. It has a crystal clear display, is extremely easy to use and very affordable.
October 05, 2015 by Digital Game Technology
DGT will have its annual stand at the Spiel '15 games fair in Essen, Germany October 8-11. Please visit our stand in hall 1, stand F-149.
The main products of DGT are game related: digital clocks and electronic boards for chess and draughts.
As a leading electronics and digital company DGT develops innovative ideas with courage and enthusiasm. With our quality products and unique services we want to add fun, fairness and excitement to all games.


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New England's offense is struggling in nearly every category this season, but third quarter scoring fell under particularly harsh light after Sunday's loss to the Jets.
The Patriots have scored just nine third-quarter points in seven games this season.
"I don't think there's been one consistent theme," offensive coordinator Josh McDaniels said of the stat. "I think that there's no magic formula for any team to come out and do well, whether that's the beginning of the game or the third quarter. I'd love to say that there's a personnel grouping or a style of play or certain types of play calls that could insure us a certain level of success, but I don't really believe that that's the case."
McDaniels took responsibility. Though there's never a guarantee for success on game day, he admitted there should be certain plays ready to go, adjustments to try, and a better effort to continue taking advantage of first-half successes.
"That's really where my focus is going to be," he explained. "I know ultimately whatever we choose to do, we've got to put our guys in a position where they can execute and succeed, so I think we've just got to keep grinding away at it. It's not for lack of effort on anybody's part, and I think that we'll definitely take a look at everything we've done and try to improve in every area, including the beginning of the second half."
That is where the Patriots fell apart last Sunday.
Out of the break, New England gained -5 yards on the first four drives against the Jets. New York took advantage of its opponents' impotency and flipped a 21-10 deficit to a 27-21 lead before the fourth quarter. Tom Brady completed just 22-of-46 passes on the day after going 11-for-18 through the first 30 minutes. Considering his first series of the second half ended with a pick-six, the offense actually contributed to the Jets' cause quite a bit.
McDaniels said the halftime process rarely changes. They look at what they've done, how the defense has played them, and what calls and personnel situations they're facing. New England then game plans for the second half with that intel.
"Some teams make a lot of adjustments, some teams don't, and I don't believe Sunday was a situation where there were a lot of dramatic changes in the third quarter," the coordinator said. "We've just got to find a way to play better."