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Guerraty, Marie; Mohler, Emile R. III
From the Vascular Medicine Section (M.G., E.R.M.), Cardiovascular Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA.
This work was supported in part by the American Heart Association and a National Research Service Award (National Institutes of Health).
Address correspondence to: Dr. Emile R. Mohler III, Hospital of the University of Pennsylvania, 4th Floor Penn Tower Bldg, 34th and Spruce Streets, Philadelphia, PA 19104; e‐mail: firstname.lastname@example.com.
Aortic valve stenosis is a complex inflammatory process, akin to arterial atherosclerosis, involving lymphocytic infiltrates, macrophages, foam cells, endothelial activation and dysfunction, increased cellularity and extracellular matrix deposition, and lipoprotein accumulation. A clonal population of aortic valve myofibroblasts spontaneously undergoes phenotypic transdifferentiation into osteoblast‐like cells and forms calcific nodules in cell culture. Animal models complement these cell culture models by providing in vivo systems in which to study the complex molecular and cellular interactions that cause aortic valve disease in the native hemodynamic and biochemical environment. Whereas some species, such as swine, can develop spontaneous vascular and valvular atherosclerotic lesions, others, such as rabbits and mice, have not been shown to develop lesions naturally and require an inciting factor, such as hypercholesterolemia. In this article, we review the published cell culture and animal models available to study calcific aortic valve disease.
Aortic valve sclerosis (AVS), defined as leaflet thickening with focal areas of calcification without commissural fusion and without significant left ventricular outflow obstruction, affects over 25% of people over 65 years of age.1,2 Sclerosis can progress to stenosis, causing symptoms of left ventricular outflow obstruction, at which point the only treatments are medical management of symptoms and heart remodeling or valve replacement for severe stenosis. AVS was once believed to be a passive degenerative disease, but recent research has shown that it is actually a complex inflammatory process, akin to arterial atherosclerosis, involving lymphocytic infiltrates, macrophages, foam cells, endothelial activation and dysfunction, increased cellularity and extracellular matrix deposition, and lipoprotein accumulation.3‐6 The risk factors for AVS are similar to those for atherosclerosis and include advanced age, male gender, smoking, hypertension, hypercholesterolemia, and diabetes, as well as raised serum calcium and creatinine.7‐9 In this article, we review the published cell culture and animal models available to study calcific aortic valve disease.
The aortic valve is supple tissue that contains a single layer of endothelial cells that envelop a spongiosa layer made up of loosely organized connective tissue on the aortic side and a ventricularis layer containing elastin on the ventricular side. The interstitial myofibroblast, a cell with many similarities to the smooth muscle cell and fibroblast, resides in the interstitial layer of the valve and is thought to assist in maintaining valve integrity in response to mechanical motion, which occurs approximately 100,000 times per day. The myofibroblast normally secretes collagen and other matrix tissue proteins that support the valve architecture. However, the myofibroblast may undergo transdifferentiation, similar to that observed with smooth muscle cells, and participate in pathologic calcification.
A clonal population of myofibroblasts spontaneously undergoes phenotypic transdifferentiation into osteoblast‐like cells and forms calcific nodules in cell culture (Figure 1). The time frame resulting in nodule formation is dependent on the culture substrate and media. Aortic valve myofibroblasts from dogs, pigs, and sheep develop well‐formed calcified nodules in 2 to 3 weeks when cultured on plastic. Human myofibroblasts also develop calcified nodules but develop later, after 4 weeks of culture. Calcified nodules are seen earlier if myofibroblasts are cultured on collagen. The number of calcified nodules increases when β‐glycerophosphate is added to cell culture media.
The clonal population of animal myofibroblasts that forms calcific nodules shares similar phenotypic traits found in human calcified valves, such as secretion of alkaline phosphatase, and extracelllar matrix proteins, such as osteopontin, bone morphogenetic protein 2, and matrix Gla protein (MGP).10 One protein, transforming growth factor β1 (TGF‐β1), which localizes within interstitial cells, inflammatory cells, and calcific deposits in clinical pathology studies of calcific aortic stenosis cusps, also promotes calcific nodule formation.11
Matrix metalloproteinases (MMPs) are zinc‐ and calcium‐dependent endopeptidases that are involved in tissue remodeling and implicated in aortic valve disease. Tenascin (TN‐C), an extracellular matrix glycoprotein found in developing bone and atherosclerotic plaque, when added to cell culture media resulted in increased myofibroblast MMP‐2 messenger ribonucleic acid expression and MMP‐2 gelatinolytic activity (both pro and active forms) compared with control.12 MMP‐9, also present in calcified aortic valves, is secreted only in myofibroblast cultures that contain TGF‐β1.13
Calcified aortic valves contain cholesterol and by‐products such as 25‐hydroxycholesterol and were found to stimulate the formation of calcific nodules in cell culture.10 3‐Hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase inhibitors (statins) are currently being tested in clinical trials to determine if cholesterol reduction can halt the progression of aortic valve disease similar to that seen in coronary and carotid arteries. There is in vitro evidence that supports statin therapy as statin drugs were found to inhibit nodule formation via inhibition of the cholesterol biosynthetic pathway and independent of protein prenylation.14 Interestingly, alkaline phosphatase, an important enzyme in calcification of tissue, was also inhibited by statins. Although cell culture experiments do not recapitulate in vivo conditions, the study of calcification of valve interstitial cells such as myofibroblasts may yield insight into the pathologic process and is a simple method for screening potential therapeutic compounds.
Animal models complement these cell culture models by providing in vivo systems in which to study the complex molecular and cellular interactions that cause aortic valve disease in the native hemodynamic and biochemical environment. Whereas some species, such as swine, can develop spontaneous vascular and valvular atherosclerotic lesions, others, such as rabbits and mice, have not been shown to develop lesions naturally.15,16 Conducting experiments on these spontaneous lesions is both inefficient and costly. It is therefore necessary to incite or accelerate the pathologic process by exposure to known risk factors (male gender, age, hypercholesterolemia, hypercalcemia). Several insults to the aortic valve, including advanced age, certain genetic backgrounds (apolipoprotein E, LDL receptor, MADh6, and MGP knockout mice), certain high‐cholesterol, high‐fat, and high‐carbohydrate diets, or combinations of these, have proven effective as outlined below (Table 1). The following models are useful not only for understanding the pathophysiology and natural progression of AVS, but also for gauging the effects of various therapeutic interventions. They may also serve as model systems in which to investigate AV bioprostheses, though this is beyond the scope of this discussion.
Since we are ultimately interested in understanding the mechanism, progression, and treatment of AVS in humans, previous pathologic studies that characterize AVS lesions in humans serve as the gold standard against which to evaluate animal models. Ideally, the AVS induced in animal models would be similar to that of humans in both pathology and distribution; the natural progression of the disease would mirror that in humans; and the models' response to therapies would approximate that of humans. The pathologies incited in animal models should therefore include the following to some degree: leaflet thickening owing to a complex inflammatory process involving lymphocytic infiltrates, macrophages, foam cells, endothelial activation and dysfunction, increased cellularity and extracellular matrix deposition, and lipoprotein accumulation, as well as calcifications, chondroid or osseous metaplasia, or angiogenesis in more advanced lesions.3‐6,17,18 Similarly, in vivo measures of AVS should parallel those seen in humans and include an increased transvalvular velocity, which suggests an increased transvalvular pressure gradient across the aortic valve or a decrease in the aortic valve area.
Mouse models are perhaps the most widely used animal models to study AVS. Their low cost and easy management, along with the availability of clonal samples and genetically mutated strains, have made them a convenient model, for example, a knockout model of Madh6, which encodes the inhibitory, TGF‐β1 signaling mediator protein SMAD6 and causes valve hyperplasia, as well as cartilaginous metaplasia and advanced ossification of the aortic media.19 Smooth muscle cells and chondrocytes of MGP knockout mice calcify spontaneously, leading to premature calcification and massive calcification of the aortic valve and major arteries.20
Mouse models have also been used to study AVS as an aging phenomenon by allowing mice susceptible to atherosclerotic processes to age until they develop valvular disease. This mirrors the progression of AVS in humans where exposure to a systemic risk factor for extended periods of time leads to pathologic changes. Weiss and colleagues allowed low‐density lipoprotein (LDL) receptor knockout mice with only apoliprotein B‐100 to age for approximately 20 months.21 The mice developed moderate hypercholesterolemia and aortic valve disease and, interestingly, showed signs of left ventricular hypertrophy and a decreased ejection fraction, which are characteristic of the clinical syndrome that usually accompanies advanced AVS.21 This model is particularly interesting since it develops the heart disease and hemodynamic effects of aortic valve stenosis, approximating not only valvular pathology but also the ensuing clinical syndrome.
Apolipoprotein E‐deficient mice also develop an increase in transaortic flow velocity with age indicative of aortic valve stenosis.22 Aikawa and colleagues studied these early lesions and found that the aortic valves thickened, contained macrophages and showed early dysfunction in vivo.23 Furthermore, they identified the presence of early biomarkers of AVS in vivo.
A high‐fat, high‐carbohydrate diet, perhaps more relevant to humans than a purely hypercholesterolemic diet, administered to wild‐type and LDL receptor knockout mice resulted in increased transvalvular velocities, that is, decreased aortic valve area, with leaflet thickening and calcium deposition.24
Rabbits have also been used to study early to advanced aortic valve disease. In general, a hypercholesterolemic diet is administered to promote pathogenesis. A 4‐week hypercholesterolemic diet revealed that LDLs accumulate immediately beneath the endothelium and associate with collagen fibers in the extracellular matrix.25,26 A longer, 12‐week, hypercholesterolemic diet induced lipid‐rich lesions and caused an increase in the number of apoptotic (TUNEL positive) cells in the aortic valve.27 When coupled with vitamin D‐induced hypercalcemia, the dietary insult also led to significant calcium deposition and aortic stenosis, detectable by echocardiography.28 Twenty‐ and 40‐week hypercholesterolemic diets also successfully induced early AVS pathology and revealed osteopontin expression in these early lesions.29 Aortic valves from rabbits maintained on a hypercholesterolemic diet for 1 to 20 weeks revealed that β‐very low‐density lipoprotein endocytosis increased after a few weeks and was greater on the aortic side of the leaflet than on the ventricular side.30
Rabbit models have also proven useful in studying the effect of potential therapies on AVS. Rajamannan and colleagues found that atorvastatin administration mediated the cellular proliferation and expression of osteogenic genes induced by hypercholesterolemia.31
Since they can develop spontaneous vascular and valvular lesions, porcine models have been widely used to research atherosclerosis.15 When subjected to an atherogenic diet, swine display lipid profiles comparable to those of humans, particularly with respect to LDLs,32 and atherosclerotic lesions ranging from fibromuscular plaques to more advanced lesions with lipid deposition, calcification, and cholesterol clefts (Figure 2).33‐35 Furthermore, the pig genome is comparable to that of humans in size and is homologous to humans in both sequence and chromosomal structure, making porcine models particularly useful for genomic studies of the aortic valve. Simmons and colleagues used such a model to study the correlation between phenotypic heterogeneity and regions of susceptibility in normal valvular endothelium.36 Since porcine valves are often used to replace dysfunctional human aortic valves, studying the pathophysiology of AVS in swine is also relevant in its own right.
Patients with congenital bicuspid aortic valves develop aortic valve sclerosis and stenosis at an accelerated rate compared with those with normal, trileaflet valves. Both endothelial nitric oxide synthase and Notch1 knockout mice develop congenital biscuspid valves and could potentially serve as useful models for both the congenital disease and the process and progression of AVS.37,38
We thank Peter Davies, PhD, for his advice and support of this review.
Key words:: calcification; aortic valve; atherosclerosis
This article has been cited 7 time(s).
© 2007 American Federation for Medical Research
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I would like to see a law passed that states all of our elected officials must have their name, address and hone number published in the White Pages of our local telephone book.
After all, they were elected to serve the public, not hide from the public.
Joe Renner
Goldens Bridge

subset: commoncrawl


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Im no mining expert, but comparing to other drill programs theses guys are finding HIGH GRADE consistently in every hole, compared to one great hole and 20 holes that have nothing worth reporting. Im amazed at the share price as well, at the same time i am tired of pump an dump stocks so if this can keep putting out consistent results i would be quite happy to slowly pick away at more shares.
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Ronald Brummer
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A Plover man accused of fracturing his baby son's leg last year spent time in jail for hitting the child's mother while she was pregnant, Waupaca County Circuit Court documents show.
Ronald Brummer, 27, was ordered held on a $2,000 cash bond Tuesday. He also was told not have to any contact with the now almost 2-year-old boy.
Brummer faces charges of child abuse and substantial battery after grabbing the 2-month-year-old's leg and twisting it out of frustration in April 2012. ...


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hakeem nicks - Page 3
Diary of a Giants Fan: Giants Lose a Heartbreaker – Grades
Diary of a Giants Fan – Giant Disaster Versus Philly – Grades
Diary of a Giants Fan: Giants Fall to 49ers – Grades
Diary of a Giants Fan: Giants-49ers Preview
Diary of a Giants Fan: Giants – Patriots Preview
5-2. Who knew? First place in the NFC-East. Who saw that coming? Two possibly devastating injuries to stars? Well, that one's pretty much par for the course this year. With no word on whether Hakeem Nicks (hamstring) or Ahmad Bradshaw (foot) will be available, the Giants will begin to run the gauntlet that is their second half schedule on Sunday when they take on the New England Patriots. This is Diary of a Giants Fan.
Hakeem Nicks To Have MRI
Diary of a Giants Fan: Giants Win an Ugly One – Grades
It was an ugly, ugly, brutally ugly game in the Meadowlands Monday night. And not that great old time, bruising, smashmouth type of ugly typified by the '86 Giants, who's Super Bowl win was celebrated at half time. This was just good old fashioned sloppy ball. But hey, they got the win. So who cares what it looked like?
Diary of a Giants Fan: Week 2 Preview
Well Giants faithful, let's just be honest. Last week was awful. Sunday's loss was a masterpiece of mediocrity, if mediocrity isn't overselling it. But we know this, it's been covered…agonizingly. So let's turn away from that debacle and look forward. How will the Giants fair under the bright lights of Monday Night Football versus the upstart Rams? This is your Diary of a Giants Fan week two preview...electric boogaloo.
Diary of a Giants Fan: Redskins Dismantle Giants – Grades
Giants Limping Into Season Finale
Mother Nature Orders A Stay For The Streak
Vikings quarterback Brett Favre has played through all sorts of injuries and overcome all kinds of personal anxiety to play the game of football. But tonight, his streak of 297 consecutive starts was given a glimpse of hope in becoming 298 thanks to Brett Favre's new best friend: Mother Nature.


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John Ryan
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goodness Mfg. Mocks 'Sillycon Valley' for Toshiba - Posted July 15, 2014
goodness Mfg. takes on Silicon Valley in a new spot for Toshiba, presenting their Encore 2 as "the one device that quiets the hype." In the animated, 30-second "Sillycon Valley," goodness Mfg. presents a cartoonish tech world gone overboard, complete with coffee drones, 5D printing and "smart scissors." While disparaging tech to... [GalleyCat]
And Now, Toshiba Toughness from goodness Mfg. - Posted March 7, 2013
The latest Toshiba campaign from goodness Mfg. provides plenty of answers. Can a Toshiba television withstand the humidity in a sauna? Yes. Can a Toshiba laptop hold up after being violently thrown from a paint shaker? Yes. Can a Toshiba laptop survive under the weight of a monster truck? Not exactly.... [GalleyCat]
Tori Spelling Hosts Glad ForceFlex Black Bags Reality Show Starring Animals Because This Is Where We Are Now - Posted October 9, 2012
Who could forget Glad and EVB's charming spoof of reality TV "The Wild Life," which followed the messy living habits of anthropomorphic woodland creatures? Yes, watching the trashiness of puppets covered in trash drove America absolutely fanatical, with the national phenomenon causing grocery ... [GalleyCat]


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The Permissions required to operate Unmanned Aircraft
All aircraft, including unmanned aircraft, must be operated in a manner that does not create a hazard to people or property. Even very small aircraft can be a hazard when operated in close proximity to people or property and could potentially inflict critical damage to other airspace users.
Articles 166 and 167 of the ANO 2009 explain the specific circumstances in which operating permission must be obtained from the CAA. In summary, permission is not required for aircraft of 20 kg mass or less being flown within direct unaided line of sight and away from people, property and congested areas. Most other operations, including flights in congested areas and those conducted for Aerial Work purposes, will require prior permission from the CAA.
In order to ensure that sufficient safety measures have been put in place, operators that are required to apply for permission from the CAA will be asked to demonstrate that they have considered the safety implications and taken the steps necessary to ensure that the aircraft will not endanger anybody. This may be as simple as preparing a safety case (and/or risk assessment) for a one-off flight. Regular operators may choose to submit an operating manual for approval which will allow them greater freedom to operate regularly without the need to seek further approval from the CAA.
To assist with the production of an operating manual, operators might wish to use the SUA Operations Manual Template.


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Wallabies hit by injuriesComment on this story
Sydney – Australia have been hit with a double injury blow two weeks out from their opening Rugby Championship match against the All Blacks in Sydney, losing prop Laurie Weeks and winger Joe Tomane.
Three-Test Waratahs prop Paddy Ryan and uncapped Melbourne Rebels wing Tom English have been called into the squad as replacements, coach Ewen McKenzie said Sunday.
Both Weeks and Tomane have hamstring injuries and are expected to be sidelined for two to three weeks.
"As it is with sport, injuries provide an opportunity for other guys to come through, and I'm sure Paddy and Tom are both excited about taking part in our preparations for the All Blacks," McKenzie said.
Ryan and English have both had exposure to the national program this year, with Ryan earning his third Test cap in Australia's victory over France in Melbourne in June, while English was part of the Wallabies training squad.
"It's no secret we're trying to build more depth at tighthead prop and the upcoming fortnight will be a good chance for Paddy to continue improving at this level," McKenzie said.
"Tom is a guy we are continually learning more about and is someone who impressed us with his attitude and abilities at training during the June series, along with being a consistent performer for the Rebels throughout the year."
The Rugby Championship involves Australia, New Zealand, South Africa and Argentina with the Wallabies playing the All Blacks, the defending titleholders, in the opening match in Sydney on August 16. – Sapa-AFP
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Mar 14, 2012 09:48 PM|JSawyerNJ|LINK
I am in the process of migrating from IIS6 to IIS7.5 . Moving away from frontpage extensions, I have installed WebDAV module for publishing. Publishing works fine if I do not upload any application using forms based authentication. I understand FBA cannot be enabled at the same time Windows Authentication. Can WebDAV work with Forms Bases Authentication enabled? If not, what is the best way for Visual Studio programmers to publish to IIS7.5??
Mar 20, 2012 07:05 AM|London|LINK
Web Deploy tool is a option;


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December 1, 2015
Target opened its doors in Dothan for the first time Sunday morning.
Many shoppers were waiting at the front door to get their hands on the big sale items of the day.
Target also features a Starbucks inside, an addition to Dothan many residents are excited about.
Target is open seven days a week, and will have sales to encourage new customers throughout all of next week.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or email@example.com.


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Our Mission: is to facilitate a community based conversion of the former CPR right of way between Goderich & Guelph, Ontario, to a non motorized trail connecting local communities.
The Elora Cataract Trailway is a 47 km linear greenland and section of the Trans Canada Trail system which follows an historic railway line joining two major watersheds, the Credit River and the Grand River.
Scarborough, Ontario, located in the eastern part of the city of Toronto was almagamated with the city in 1998. The region is culturally diverse, with the vast majority of residents having arrived as immigrants in the last forty years.
The 10.5 km G.A.R.T. on the abandoned Canadian Pacific Railway line, offers cyclists an accessible and safe off-road experience. While on the trail, cyclists will enjoy wildlife, trees, wildflowers and views of the Maitland River as well as post-glacial kettle lakes.
Enjoy this route and tour about downtown Toronto, taking in many of the city's landmarks and neighbourhoods. Distance & Timing: 17km, 3 hour+ recommended and depends on number of stops.
Take a break at the last covered bridge in Ontario and enjoy some great views of the Grand River. Also known as The Kissing Bridge, lovers have long used this spot to steal a kiss under the privacy of the covered bridge.
Enjoy the Mennonite countryside of Woolwich Township. Explore the villages of West Montrose (and visit the last covered bridge in Ontario), Elmira, St. Jacobs, Winterbourne.
The Saugeen Rail Trail is a year round, multi-use trail that connects Southampton and Port Elgin, Ontario. Built on an old railway line the trail is easily accessed and used by visitors and residents alike.
The 47 km Huntsville to Bracebridge is a road ride listed by the Muskoka Cycling Club and described as rolling hills.
It's a casual ride for the casual cyclist, and since it takes the form of several loops, there are several points at which you can decide whether to do the whole route or opt out at one of the central junctions.
This tour starts and ends in the town of Port Rowan. There are many places to park along the main street and in a few parking lots, including at the Country Coffee on Bay Street. Alternate places to start/end include the small village of Forestville.
Camp at the Haldimand Conservation Area, Selkirk Provincial Park, or Sweet's Corners, or stay at one of the B&B's along the way. Food stops are in historic Selkirk, Fisherville, Sweets Corners and Cheapside.
The Lennox & Addington County Trails include 12 looping routes consisting of 600 kilometres of paved roadway where you never retrace your path, yet are able to end where you began.
This 26 km circle tour starts and ends at Jordan House B&B. Proceed west along Eighth Line to North Buxton, turning left (south) on the A.D. Shadd Road. First stop, Buxton National Historic Site. Continue south along A.D. Shadd Road to Wind Turbines.
Niagara Cycling Maps - When it comes to cycling, Niagara has it all! Whether you are looking for flat, country roads or something more challenging (hey, climbed the escarpment lately?), the Niagara region offers something for everybody.


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I'm looking for a white or black (only these colors please) Dodge Cummins Megacab 3500. Will also look at 2500 if have all other specifications.
Would prefer to find a low mileage '07 5.9L but will look at the newer years that are 6.7L. Please no older than '05.
Needs to be fully loaded (Laramie) with heated leather seats, sunroof and DVD entertainment system in the back (factory). Front can be either bench or 2 bucket seats, no preference there.
Please let me know if you have anything that fits this description, or know of anyone who does. Willing to travel for perfect truck.


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Congressional officials have been applying a steady stream of pressure to the union to bend on HGH testing. The union believes there needs to be more information and safeguards inserted into testing protocols while the NFL believes testing is ready to start now.
Well, Congress has launched another salvo. This time a group of doctors turned Congressional officials have wriiten a letter to the union and NFL urging them to end their HGH impasse. You can read the letter here.
Will this work? I don't know. The union is convinced there needs to be more research done and I'm not sure they will budge.
So the HGH impasse will likely continue.


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(For undergraduate degree see Admission Requirements)
Prior Degree
You are required to have completed or be in the final year of a Bachelor's degree. This must be from an Australian university or another recognised tertiary institution of equivalent standard. It may be in any area of study and there are no specific subjects required as prerequisites. If you are in the final year of study, satisfactory completion of the degree will be a condition for entry.
Strong performance in the Bachelor's degree is an important indicator of the intellectual abilities necessary for medicine. When Flinders ranks applicants after interview, your weighted grade point average (wGPA) makes a significant contribution to your overall selection score. Your wGPA is based on the last 3 full-time equivalent years of study in your most recently completed Bachelor's degree (including an Honours year if applicable). It is determined by weighting final year studies x3, second year studies x2 and first year studies x1.
No other qualifications (eg, Masters, PhD) will be included in your wGPA. Wide variations in grading systems make valid comparison of grades across such programs and institutions difficult. However, higher degrees may provide relevant and valuable experience that could help your interview performance.
You do not need to calculate your wGPA. We will do this when you apply based on your transcripts. Unfortunately we do not undertake such calculations before you submit a application.
Admissions test
You will be required to submit results of a medical school admissions test. This is essential to ensure that commencing students understand the principles and vocabularies of the basic disciplines that underpin the medical course. It also acts as a major discriminator in the application process.
Flinders accepts either GAMSAT or MCAT test results. Neither will be given preference in the selection of international students.
Please see the GAMSAT website for test locations, timelines, test questions and further information. This test is usually held in March in Australia, but there are overseas locations at different times. We will accept any GAMSAT score from 2013, 2014 or 2015 for 2016 entry. You will require a minimum standard in each section of GAMSAT in order to be considered further in the admissions process (normally 50 for Sections I, III and the total score, and 46 for Section II).
MCAT testing is available at various times throughout the year and in numerous countries. We will accept MCAT scores as far back as August 2012 for 2016 entry. As of 2013 we will normally expect minimum MCAT scores of 8/8/8 (24 total). For the new MCAT in 2015 we will normally expect minimum MCAT scores of 123/123/123/123 (492 total).
If you have sat these tests more than once, we will automatically accept your highest score in the eligible timeframe.
English Language Requirements
Applicants must satisfy our Flinders English Language proficiency requirements of Level 5 or equivalent
Short-listing for international interviews is based on a combination of an admissions test score and a wGPA from an applicant's most recent Bachelor's degree. Invitations to interview will normally be in May and July/August each year (refer timeline). Interviews may be offered at other times subject to our discretion.
If you are invited to an interview and reside overseas, you will not be expected to travel to Australia. However you are most welcome to visit Flinders (and potentially schedule an interview to coincide with this, if short-listed). If you reside in the corresponding countries below you will be expected to attend the interview in person: Adelaide (for Australia); Singapore (for Singapore), London (UK), San Francisco or LA (for USA), Vancouver and/or Toronto (for Canada). For all other countries, at our discretion, we may offer a Skype interview. Applicants must meet their own costs of travelling to attend interviews.
Our semi-structured interview is used to assess personal qualities of applicants. The interview has a common set of scenarios and questions for all applicants, to assess qualities considered important both for success in medical school and in subsequent medical practice. These following qualities were identified by consulting within the Medical School and the wider community:
- Quality of motivation
- Learning style and team skills
- Communication skills
- Pro-social attitude
- Personal management and self-evaluation skills
- Approach to decision-making
Where possible, international interviews will be linked with a briefing session on the Flinders program. This is a common session for all interviewees on the day of their interview.
Details for submission of applications and subsequent steps are outlined under Application and Selection Process for international applicants.


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College Soccer Reporter
> Friday, Sept. 19, 2008
MORNING BRIEFING: Howard plummets
by Paul Kennedy
Howard, one of the great names in college soccer, is a program in big trouble. Its head coach was replaced after being arrested earlier in the year in a youth sex sting. And it is off to an 0-6-1 start with losses as bad as 9-1 and 8-0. ALSO: UC ...
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CONFERENCE WATCH: WCC teams slump
by Soccer America
The West Coast Conference includes two former national champions -- San Francisco (1966, 1975, 1976, 1980) and Santa Clara (co-champion in 1989) -- and two other teams that have played in the final four -- San Diego and Portland -- but this season has been a non-starter for WCC teams. ...
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SCOREBOARD: Soccer America Men's Top 25
by Soccer America
[WEEKEND UPDATE] No. 2 SMU suffered its first loss of the season when it fell to Northern Illinois, 1-0. In Top 25 matchups, Maryland beat Duke, 1-0, Boston College defeated North Carolina, 4-1, thanks to Alejandro Bedoya's hat trick, and Cal prevailed over Drake, 2-0, to hand the Bulldogs' their ...
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MORNING BRIEFING: Upset that was not an upset
by Paul Kennedy
James Madison beat No. 16 Penn State 1-0 before a school-record crowd of 1,829 fans -- more than double the previous high -- and a national television audience Thursday evening at the JMU Soccer Complex. ALSO: N.C. State, the only unbeaten and untied ACC team, makes a comeback ... West ...
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SCOREBOARD: Soccer America Women's Top 25
by Soccer America
Notre Dame will put its No. 1 ranking on the line this weekend when it travels to DePaul and Penn State. No. 4 Portland hosts surging Florida, while Virginia plays West Virginia in another battle of Top 25 teams. For this week's Soccer America Women's Top 25 results and schedules ...
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110cc Fully Automatic Gas Go Kart
Everything Must Go!
Credit Report:
Plainfield, IL
Call 1-866-606-XXXX with questionsPlease visit http://www.saferwholesale.com/gokarts to view our full selection!Specifications:Engine / PerformanceEngine: Single Cylinder, 4-stroke Air cooled 110ccTransmission: Automatic- Forward, Neutral, Reverse (via shift lever)Final Drive: ChainIgnition System: CDIStarting System: Turn Key ElectricBattery: 12V-6.5AHMaximum Speed: 25+ MPH, +/- 5MPH (Depending on Riders Weight and Road Conditions)Fuel Capacity: 0.60 GallonsChassis / SuspensionTires: Front 145/70/6; Rear 16 x 8.0 x 7Frame: Steel TubeFront Suspension: Independent A-ArmRear Suspension: Swingarm - Dual ShocksFront Brakes: N/ARear Brakes: Single DiscLighting / ControlsLighting: Headlights, Turn SignalsControls: Headlight switch, Turn Signal Switch, Horn Button, Choke Pull Knob, Kill Switch, Mirrors, Shift lever, Pedal Operated Throttle and Brakes, Parking Brake, Seat Belts: Rider and PassengerInstrumentation: N/ASpeed Governor: NTool Kit: YOwner's Manual: NCapacities / DimensionsWeight: 264 lbsHorsepower: 3.4Overall Length: 77 inches (assembled)Overall Height: 47.50 inches (assembled)Overall Width: 43.75 inches (assembled)Ground Clearance: 8.50 inchesSeat Height: 13 inchesWheelbase: 56 inchesAge/Height Recommendation: 12+
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110cc Fully Automatic Gas Go Kart is a Other Vehicle in Plainfield IL. Find other listings by searching for Other Vehicles in Chicago on Oodle Marketplace.


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Frankenstein Sundae, 179
2 hours ago
A beautiful and ancient Eastern problem, bringing to mind the Insolubilia of Zippy.
Have we buckled our seatbelts and returned the trays to upright position yet?
It's nice to be able to be reflective, light and witty about this problem. During the four years I worked for a Chicago-based company (I lived in New York and was on planes for them at least four times every week), I basically lived in a completely amnesic, disconnected state. Curtis


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(The following post comes from WSJ's Law Blog.)
By Joe Palazzolo
Here's an interesting question: How many iPhone apps, or apps generally, could be used for illegal purposes?
Sen. Robert Casey (D., Pa.) says he's found one, at least: DriversEd.com's Drivers License app, which let users pose for photos and create images of drivers' licenses with their mugs on it.
Casey said in a statement Apple yanked the app from its App Store after he complained of its potential as a tool for making fake IDs. In the app's reviews, several users commented that they had used it to make fake licenses, according to Casey's office.
"I urged Apple to take the responsible step of removing this dangerous app, and I'm pleased that the app is no longer available in the store," Casey said.
Continue reading on Law Blog.
For the latest news and analysis, follow @wsjd.
And like us on Facebook to get our news right in your feed:
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More from WSJ.D: And make sure to visit WSJ.D for all of our news, personal tech coverage, analysis and more, and add our XML feed to your favorite reader.


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Originally posted by S. C. Huey: Yesterday I started noticing some funny stuff happening when browsing on the web. Sometimes what I type in the browser address bar gets redirected to a site called search-aid.com!!! How is this possible? Wouldn't they have to override something in IE, even replace some of IE's code? Or is this site actually what Microsoft uses now? Obviously I find that hard to believe, and so I'm wondering how to get rid of this search-aid.com junk. I've already scanned with Ad-Aware and Norton, and I deleted some junk I found on my computer yesterday, but this problem hasn't gone away, and I've been trying to figure out how to locate the source of it on my hard drive! Naturally, search-aid.com has no info up about who they are. For example, if I type in localhost on my address bar (which I would often do before), it now takes me to this URL: http://www.search-aid.com/search.php?qq=localhost I hate this insidious stuff! I know it wouldn't be right, but it certainly makes me feel like writing software to crash their site. Unfortunately, I suppose they're more than ready for traffic since that is undoubtedly what they want more than anything else.
Originally posted by S. C. Huey: You know, I think Ad-Aware helped me get rid of a little bit of really nasty junk, but that and PestPatrol and SpyBot seem to focus a little too much for my liking on cookies. I mean, a lot of cookies don't bother me a bit. I've got more annoying issues going on that they're NOT finding! I wish Win XP gave me more info about processes that are running in the Task Manager!!!


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Defining sources of reliable and clean electric power is a global priority. And as a result, wind power has become one of the most significant energy industries in the world today.
Hatch has played key roles in most of Canada's installed wind capacity. Our capabilities include wind assessments, feasibility studies, site research, engineering design services, project management, interconnection services, environmental assessment and permitting services, construction supervision and due diligence.
Hatch integrates wind and hydro projects into single generating systems, and provides decision-support software and expert analysis to ensure optimum system efficiency and reliability.
As part of our engineering and project management services, Hatch has also developed software that helps clients optimize financial returns from their wind projects.
Our services include:


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What is a Substation/Switchyard ?
A substation is a part of an electrical generation, transmission, and distribution system, where voltage is transformed from high to low, or the reverse, or many other important functions.
What is a switchgear ?
The term switchgear, refers to the combination of electrical relays, fuses , circuit breakers, contactors etc used to isolate/ control electrical equipment.
Switchgear is used both to de-energize equipment to allow work to be done and to clear faults downstream.
ashwani permalink
easy to learn


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West Lafayette Police Chief Jason Dombkowski talks on the phone Jan. 21 after a shooting at the Purdue University Electrical Engineering Building in which a student was killed.
- Filed Under
Before the questions started, there was a moment of silence the afternoon of Jan. 27 for Andrew Boldt.
Then Purdue University President Mitch Daniels' remarks to the University Senate, a governing body of faculty and administrators, turned to the aftermath of the deadly shooting on Purdue's campus that left Boldt dead and another student charged with murder.
Did the campus alert system work fast enough? ...


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By Varietal
I had some bleu cheese in the house for some reason, and decided to create my own version of my wife's (Amy) favorite burger. According to her, it is her favorite version.
This is a a burger that is to mirror the light, refreshing Panzanella salad.
this burger is above all burgers. It has everything in it.
This is a simple and easy burger to make but tastes delicious. It sounds complicated but even the unexperienced cook can make it just by following the directions.
This burger, which is a variation of the pimento cheese burgers found in the South, is messy and delicious!
This burger was inspired by a recipe for stuffed Portobellos.
The nutty flavors of the walnuts and the Chanterelles pair nicely with the ground beef to make these elegant, but simple burgers.
One of the richest most flavorful burgers I have ever eaten. The king of all burgers. Save this one for royality please or a great backyard BBQ.
Preparation Time: 15 minutes Cooking Time: 14 - 17 minutes Serves: 6
This burger is the poor-man's version of the the expensive dish, but pity the poor rich fella who never tries it!
Prep Time: 30 minutes Cooking Time: 20 minutes Prep Ingredients: Cooking Spray Prep Supplies: Food Chopper 2 medium bowls 1 knife papertowels cutting board grilling spatula measuring spoons 2 large
A hearty BIG burger.
Growing up in New York City gave me the experience of eating food from around the globe. I learned to appreciate good cooking and fresh ingredients.
For the past 41 years I've enjoyed cooking almost daily.


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South Beach boasts warm weather year-round, which means it's bikini season every day. And while the land of excess has its fair share of decadent mealtime temptations, it also delivers in the delicious and nutritious department. These are four healthy staples with breakfast menus that help South Beach keep its bikini body all year.
Pura Vida Smoothie Bar & Cafe
- 12 points
This local go-to is located south of Fifth Street, South Beach's main thoroughfare. It is 50 percent restaurant, 50 percent mini-mart, and 100 percent delicious. Pura Vida offers an extensive menu of smoothies and traditional breakfast options to eat in, take out, or get delivered. My favorite items on the menu are their açaí bowl and their ginger shots. They also sell an array of natural snacks and other products, including some from local companies like Ginny Bakes and Coconut Cartel.1
- 10 points
This hot spot began as a juice bar with its first store in South Beach's Sunset Harbour neighborhood. Since then, it has grown by adding a handful of locations, including its newest outpost on South Pointe Drive, and by expanding its cold-pressed juice menu to include smoothies and "comida", or food. The entire menu at Jugofresh is composed of natural, whole foods, but their açaí bowl is my favorite breakfast option. Regardless of what you choose, I guarantee you will not leave their store without a bag full of healthy goodies.2
Icebox Cafe
- 10 points
If you're a late riser and want a fresh, healthy breakfast that's Oprah-approved, then Icebox Cafe is for you. This trendy restaurant in South Beach's Sunset Harbour neighborhood (a favorite of the A-lister) has a breakfast menu with both light and hearty options to satisfy all appetites. Breakfast is only served Monday through Friday from 10 a.m. to noon, but they're open for lunch and dinner until 11 p.m. and they serve brunch on weekends from 8 a.m. to 4 p.m. Make sure to dress upscale casual as this is a place to see and be seen!3
Under The Mango Tree
- 10 points
This juice and smoothie bar is an oasis in the hustle and bustle of South Beach. The cozy space offers a casual and stress-free environment in which to enjoy a nutritious meal or pick up a few health-food essentials. My favorite breakfast items are the açaí bowl and the superfood frappucino, which is made with fresh-brewed espresso blended with organic almond milk, agave, raw cacao, raw maca, and a splash of cinnamon. The ambiance and the food are the prefect way to start your day on a positive note!4


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LAS CRUCES — The building that used to house the Gadsden Purchase at 1300 Avenida De Mesilla — right behind the Comfort Inn & Suites — will soon have a new business.
Q's, which bills itself as a brewhouse with steak and pasta, is set to open in the not-too-distant future and is currently hiring.
Hotel holds groundbreaking
Hotel Encanto de Las Cruces held a groundbreaking ceremony last week for an outdoor expansion project at 705 S. Telshor Blvd. In addition, there was a grand opening for Mercedez Salon & Spa located inside the hotel.
Dairy Queen closed for renovation
The Dairy Queen located at 1773 E. University Ave. has been closed for renovations.
Indian restaurant close to opening
The Sheba Grill at 2265 S Main St., where Smokey Dicks used to be located, could open as soon as Friday, said Garadan Alamir with the restaurant. He said that the eatery will serve Indian food.


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A taste of winter arrived early here on Wednesday, October 10th with 5 inches of new snow. The first of the year. After a wet summer, we saw the grace of the Lord spare us during the Dolce fire in June. This week, I got the privilege of spending a day in the mountains west of Flagstaff scouting for Elk with our Senior Pastor. The chipmunks are busy storing up for winter.
Lets take a moment today and thank our Lord today for a country where freedom of worship still reigns. Let us thank our Lord for the blessing of this fall season. The beautiful autumn leaves. Thanksgiving. Celebrate the gift of the birth of Christianity. The resurrection of the Lord Jesus Christ. That is the only hope for mankind in these end times. Apart from a personal relationship with Jesus Christ there is no hope. Today is the day for you to truly look at your life and say "I'm a sinner and need a Savior". You're running out of time, my friend. You've tried everything else and the emptiness..it's just not worth it! Today is the day to turn your life around. Be assured that if you confess your sin and repent of your "sin centered" way of life and turn your life over to Jesus Christ, all of it, and if you commit your life to serving him and not yourself and not your job, only Jesus, you WILL be saved and will have eternal life. If you die today and do not know Jesus Christ as Lord and Savior of your life, you WILL spend eternity in hell,separated from God forever with no hope. The only hope you have in your life is to put your trust and faith in Jesus Christ and to turn everything you have over to him. That is the gospel message. Consider this before your leave this web. This might be the last chance you get. See my comment below on the public facing church in America and please leave a comment.
Reverend Sheryl and I will be spending the fall and winter renovating our cabin with some much needed storage cabinets. Both of us enjoy the outdoors and our cabin allows us many unique opportunities to enjoy the Lord in nature right here in our own backyard.
Click on the Photo Gallery link below and be "whisked away" to the North Rim of the Grand Canyon and the Colorado river. They are some of our favorite photos and we would love to share them with you.
We are a Christian based software engineering and consulting company. Our mission statement is as follows "To honor our Lord and Savior, Jesus Christ, through the ministry of software engineering". Our worldview, ethics, and business principles are based on the Word of GOD. We believe that all truth is based on Jesus Christ. That he is the WORD of GOD. That he alone is the single absolute source for all truth.
You can reach me at (928-771-8279) or e-mail me (email@example.com).
For a link to my resume click below: http://www.scguild.com/Resume/2182I.html.
My LinkedIn profile can be found at: http://www.linkedin.com/company/i-x-cel-consulting-services-inc
On Facebook: http://www.facebook.com/pages/IXCEL-Consulting-Services-Inc/117655204970355
Isn't it nice to know, my friend, that the best news you've ever heard is what you've just read. A message of truth. A message of hope. God WILL go a long way to satisfy the questions of an honest doubter. Ask God to show you who he is. See to it that you don't squander today's opportunity. Have a Blessed and Safe Resurrection Day and pray for the peace of Jerusalem. Reverend Gregory Carl White Reverend Sheryl White


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We bought a new sink counter from HD Home Supply, love that store. They have very competitive prices for builder grade /style updates. We always go there when we need to rent something { Floor Sanders, Power Snake } because their prices are so much lower then Home Depot & The staff is knowledgeable. We bought a simple white sink from there for only $ 53.00, such a good deal. Hasani installed our new sink with ease and no drips. He's working on a how to install as sink post, as I'm writing this post. Oh we opted to keep our faucet, since it was a teeny upgrade and still new-ish { 2.5 years old) Here's our old bathroom sink. In the pictures its hard to tell how dingy it was.
The new sink has made such a huge difference, our old sink was a tacky faux marble cream color, it was stained. No matter how much a I scrubbed and bleached the sucker it never look clean. I'm in love with our new clean white sink against the dark wood cabinet. I actually walked by our bathroom and few times and flipped the light on just to see how nice it looked. I need to do a little repair work above the sink, our old sinks backslash was much taller then our new one. The repair is such an easy peasy fix.
I can finally start seeing some progress in our tiny bathroom and boy does it feel good! Plus its nice to see a small bathroom update
What do you think our our little sink refresh?


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« Lost, Season 4, Episode 2 | Home | Star Wars: The Clone Wars coming to a cinema near you, soon »
February 11, 2008
Jumper, the rules. Surely a Bester namecheck required?
Jamie Bell was interviewed on Jonathan Ross's show on Friday night and he talked about Jumper. At one point he explained that they had a discussion with the director (or was it writer?) about the rules of jumping. He proceeded to list them:
- You can only jump there if you've been there before
- If you touch something it goes with you
I was waiting for an Alfred Bester namecheck, surely The Stars My Destination would be quoted as at least an influence? Nope.
Boo, hiss etc.
I haven't seen Jumper (it opens in the UK on 14th February), but watched one of those extended advert with clips of the trailer shows about it and feel I probably know the entire plot now. However, still fancy seeing it because it has cool teleport effects.
Update : SFSignal has reviews of the Jumper novels upon which the film was based (and which I knew nothing about).
1 Comment
The acknowledgments in the book do cite some previous uses of the teleportation sf trope: The Stars My Destination, Robert A. Heinlein's Tunnel in the Sky, Larry Niven's "Flash Crowd", Phyllis Einstein's Born to Exile, and Star Trek's transporter beam.
And thanks fpr the plug! :)


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A Very Old Man with Enormous Wings
by Gabriel García Márquez
A Very Old Man with Enormous Wings Story Summary
- A rainstorm causes crabs to fill Pelayo's house, and his little baby to run a fever.
- Rainstorms, crabs, illness … this is sounding pretty plague-y to us.
- When he comes back from throwing out the crabs, Pelayo notices something groaning in the patio.
- Pelayo goes closer. It's an old man, but not just any old man. This particular geezer has a pair of gigantic wings.
- Instead of freaking out, Pelayo goes to get his wife Elisenda to check out his find.
- The old man is dressed in rags, he's missing most of his hair and teeth, and his wings are totes gross, all filthy and muddy.
- Not too many beauty salons where he comes from, apparently.
- Elisenda and Pelayo try talking to the old man, but they don't understand the language he speaks back to them.
- They decide he must be a shipwrecked sailor—from space?—but decide to ask their wise neighbor just in case.
- The neighbor lady takes one look at him and declares that the old man is an angel of death who had been coming to take the sick baby, but that since he was so old the rain knocked him down and he failed in his mission.
- Baby: 1. Angel of Death: 0.
- Words spreads, and soon the whole neighborhood knows that Pelayo has an angel living in his house.
- Paging TMZ: that is some pretty hot gossip.
- The neighbor lady wants to kill the angel, because of some wacky beliefs she has about them, but Elisenda and Pelayo can't bring themselves to do it.
- Just for safekeeping, they lock the old man in the chicken coop overnight.
- The rain finally stops, and the baby wakes up cured from his fever.
- Did the old man work some magic? Elisenda and Pelayo figure better safe than sorry, so they agree to set the old man out to sea on a raft with some food and water.
- When they head out to get him, though, they see a crowd gathered around the chicken coop, checking out the angel.
- The priest is worried about all the crazy angel business, and he's moseyed on over to see what's up.
- People are coming up with ideas about what to do with the angel, like maybe make him mayor of the world, or promote him to five-star general, or even breed him and make a new race of winged men.
- The priest gets into the coop with the angel and tries speaking Latin to him, the language that priests used in Catholic religious ceremonies at that time.
- No luck—the man doesn't seem to understand Latin. Since (the priest thinks) Latin is God's language, obvs, the guy must be a phony.
- Hmm, did you try Aramaic?
- The stench, mangy feathers, and fleas don't help, either.
- The priest warns the crowd that the devil might be tricking them, and that wings do not an angel make.
- He does decide to write a letter to the bishop, asking him to write to the pope, in order to get a definitive ruling on the oldster's angel status.
- This is not as quick as a text message or an email, in case you were wondering.
- After troops—yes, troops—are called in to disperse the crowd at Elisenda and Pelayo's house, Elisenda gets the bright idea of charging admission to see the "angel."
- It's a bargain at five cents a peep.
- People come from far and wide to see whether the angel can cure their various ailments, and Pelayo and Elisenda make a killing. Cha-ching!
- The poor angel doesn't seem to enjoy the gawkers and hawkers. Weird, right?
- They're like brats at a petting zoo, trying to get him to eat weird things, plucking out his feathers, and throwing stones at him.
- Finally, they burn him with a branding iron to see whether he's alive or not.
- Well, look at that: he definitely is alive, and he reacts angrily for the first time since his arrival.
- This does the trick, and the people start to leave him alone.
- The priest investigates, writing back and forth to the Vatican.
- But the Church can't seem to decide whether the old fogey with wings is just an old fogey with wings, or a heavenly creature.
- The angel is losing credibility because the "miracles" he performs don't quite work right.
- When a blind man comes to see him, he grows more teeth instead of regaining his sight. Not too good for business.
- And then, a carnival comes to town. One of its sideshows, a woman who had been turned into a spider, steals most of the angel's audience.
- It's no biggie. By this time, Elisenda and Pelayo have gotten so rich that they've built a big, new house and bought lots of nice clothes. Pelayo is even able to quit his job.
- It turns out having an angel in your chicken coop is a lot like winning the lottery.
- Well, unless you're the angel. He's not getting a cut of the earnings, and he's still living in the filthy chicken coop.
- Elisenda and Pelayo's child, the one who had had a fever when the old man first showed up, is growing up and basically treats the angel like his pet.
- The kid and the old man get chicken pox at the same time. When the doctor comes to check them out he's shocked at how the wings seem perfectly natural, like all humans should have them.
- The chicken coop caves in, so the old man just kind of drags himself around the house.
- He drives Elisenda crazy because he seems to be in every corner, just like he's managed to duplicate himself.
- The angel starts to go blind, and he's losing feathers. (Don't worry... just because he's like the boy's pet doesn't mean this is another Old Yeller.)
- Since this situation is getting pretty pathetic, Pelayo takes pity and lets the old man sleep in the shed instead of outside.
- Oh, and he also notices that he's got a fever and seems delirious. Hm, maybe you should call that doctor?
- He's also speaking some language that sounds like it might be Norwegian.
- Elisenda and Pelayo are afraid that the old man will die and they won't know the proper protocol for a dead angel.
- Well, we're not sure the proper protocol for a live angel involves keeping him in your chicken coop … but, whatevs.
- The old man gets better as winter ends, and new feathers even grow on his wings.
- He begins to sing old sailor songs, quietly, so no one will notice.
- Finally, Elisenda sees him fly off. Whew! He's back to the realm of the imaginary, and not a real nuisance in her life anymore.
People who Shmooped this also Shmooped...


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The Team Information Management System (TIMS) is only for the main and alternate contacts of FIRST Robotics Competition teams. It is used to register new (rookie) teams, re-register existing teams for the new season, and update critical team information such as team name, contact information, and event registration.
The following registration information is also available:


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November 30, 2015
The weather couldn't be better this week to plant some flowers or lay down some bricks!
The Marietta Rotary Club is working on their centennial project, and helping the new bike path at the same time.
Members bought bricks and engraved either their name or other peoples names, and now they're laying down the bricks in a pavement patio.
Caroline Eells with Greencare says they've been looking forward to the opportunity.
" I know everybody is pretty excited about it. It's a project that was in the works for a longtime and finally we were given the go ahead to move forward."
They hope to have all the bricks laid by the end of the week.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.com.


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Yet, there was no denying that Friday's matchup between the visiting Dallas Stars -- the top team points-wise in the League -- and the Pittsburgh Penguins -- the Eastern Conference leaders -- has a big-game feel full of intriguing storylines.
Even the continued absence of Sidney Crosby, who had been rumored to make his return from season-long concussion issues Friday, won't tarnish the shine on this East-West heavyweight battle (7 p.m., NHLN-US).
"For sure, these teams like Washington and Pitt, we don't play them very much and they are both top teams in the East and we want to see how we compare to them and prove to everybody that we can play with teams like that," Michael Ryder, a free-agent addition this summer to the Stars, told NHL.com. "It's going to be a battle tonight and for us, it's a big test. We're excited about it and look forward to it."
"For sure, these teams like Washington and Pitt, we don't play them very much and they are both top teams in the East and we want to see how we compare to them and prove to everybody that we can play with teams like that. It's going to be a battle tonight and for us, it's a big test. We're excited about it and look forward to it." -- Michael Ryder
So, if he is embracing the "big-game" line, there is some definite merit to it.
The Stars are 11-3-0 this season for the League's best record. In their last game, they beat the Washington Capitals soundly, a 5-2 victory that prompted Washington coach Bruce Boudreau to punish his team with a bag skate.
Now, they face a Penguins team that has shrugged off the continued absence of Crosby, who will not play tonight or Saturday, according to the team, as he comes ever closer to a return from a concussion that has sidelined him since January.
Pittsburgh is 9-3-3 and is just one of three teams in the NHL to have lost just three games in regulation. Dallas is one of the others and the New York Rangers are the third.
The Penguins, though, were expected to challenge for top honors in the East. They have been a perennial power for the past few years and won the Cup in 2009. Plus, they possess marquee players at every position.
Dallas, meanwhile, is the season's early Cinderella story.
Stars-Penguins related content
Neal, a star in Pittsburgh, still follows StarsAlan Robinson - NHL.com Correspondent
James Neal loves playing for the Penguins, but he still keeps an eye on his old team, the Dallas Stars.
After 14 games, the Stars believe they are for real. Now, they want to prove it to the hockey world.
"When we looked at this road trip, we marked these games and said it is going to be a good way to test ourselves," said defenseman Alex Goligoski, who played for the Penguins last season before a late-season trade to the Stars. "It's a tough road trip against some good teams; this game in particular. I think they are leading the East, as usual. It'll be a good test, for sure, and I think for them, as well."
Goligoski will be a key storyline in the narrative Friday. He was traded to the Stars near the trade deadline in February in exchange for James Neal and Matt Niskanen as the Penguins tried to shore up their scoring in the absence of Crosby and Evgeni Malkin, who was sidelined with a knee injury.
By all accounts, Goligoski has been very good for the Stars, logging minutes as one of the team's best two-way defensemen and putting up 6 points in 14 games. Neal, meanwhile, has been the Penguins' biggest gun this season, totaling 9 goals and 14 points in 15 games.
But, there are countless other storylines that make this a can't-miss affair.
Pittsburgh coach Dan Bylsma agrees with Goligoski's assertion that Friday will be a challenge for his Penguins. He has had a few days to study the Stars on tape and has been impressed by what he's seen.
"It's a team we don't see very much, but it is a team that is leading the League in points," Bylsma said. They have been playing very well. Their forward lines -- Ryder, (Loui) Eriksson, (Jamie) Benn -- have been outstanding and deserving of the All-Star bids they have gotten. Benn, with his speed and his shot, has been dominant.
"Their defense has been playing very well. (Sheldon) Souray, obviously, has come back and is playing with a vengeance. You see how effective his shot can be, but he is also playing well defensively. Their goaltender has found his groove.
"It's a tough task tonight and we're looking forward to that matchup."


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Emily Explains: A Quick Knit for Saint Patrick's Day
Happy St. Patrick's Day everyone! Today was off to a horrible start when I realized I forgot to wear something green! With some yarn and needles, I got right to work during my lunch break to solve this problem. I knitted myself a four leaf clover!


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- KNIA / KRLS - http://kniakrls.com -
Relay For Life Looking For Volunteers
Posted By News On December 22, 2011 @ 6:25 am In Today's Local News | Comments Disabled
Relay For Life, a national series of fundraising events for fighting cancer, is growing in Marion County. Melissa Stuit, a volunteer for Relay for Life told KNIA/KRLS News that they are looking volunteers to help run an event next September. The relay for life events are overnight affairs where teams of people trade off walking or running a track for 12 hours to raise money to fight cancer. Stuit also said anyone who is interested in forming a team to participate in the event should start now. Cathy Struecker with the American Cancer Society is Relay for Life Coordinator for Marion County.
Article printed from KNIA / KRLS: http://kniakrls.com
URL to article: http://kniakrls.com/2011/12/relay-for-life-looking-for-volunteers/
Click here to print.
Copyright © 2009 KNIA/KRLS. All rights reserved.


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Keep Bonds' Balls Out Of Court; A-Rod Cuz Found
• Lawyers ask not to bring up Barry Bonds' testicles during testimony.
• A-Rod's needle-happy unnamed cousin has finally been found.
• Verne Gagne may have beaten his nursing home roommate to death.
• Penn State & Illinois were very offensive with their offense last night.


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jacket | Nordstrom |
top | Marshalls |
scarf | old |
jeans | Nordstrom |
boots | Rag and Bone |
bag | old - Rebecca Minkoff - love this one |
If you haven't checked out the Nordstrom Semi Annual Sale then you are seriously missing out! I snagged this leather Trouve blazer blazer for 40%. I am so in love with it. The structured shoulders take this blazer to whole new level and I can't get enough of it. (Apologies in advance if this jacket shows up a ton on here! ) Now that the weather has transitioned, I find myself reaching for a scarf every time I walk out the door. I absolutely love this one that I was gifted. The color surprisingly goes with so much and has most definitely become a winter staple for me.
| quote of the day |
"The truth of the matter is that there's nothing you can't accomplish if : (1) You clearly decide what it is that you're absolutely committed to achieving, (2) You're willing to take massive action, (3) You notice what's working or not, and (4) You continue to change your approach until you achieve what you want, using whatever life gives you along the way."
-Tony Robbins
Sarah Marie


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Skip to content
6th Mar 2012
HotLizard News, Industry News, Press Coverage
Originally launched in 2009, HotLizard's Gecko platform has seen significant uptake over the past 3 years. The Gecko product range of recruitment websites and job board software includes a suite of pre-defined creative designs, all of which have gone through extensive usability testing. This off the shelf approach enables HotLizard to implement the Gecko sites quickly, without the cost associated with bespoke recruitment website or job board design.
Due to Gecko's huge success, HotLizard has been able to invest heavily in Gecko's ongoing product development, with new features and improvements being regularly added to the core platform. One of the more recent additions to Gecko's feature list is a mobile version of the site. According to The Office for National Statistics, almost 50% of UK internet users are going online via a mobile phone; a trend that is growing year on year. With the number of internet users using mobile devices continuously increasing, HotLizard felt it was essential to offer a mobile site as an optional extra to a Gecko Website or Gecko Job Board .
Rather than limit Gecko's Mobile Website to only allow registered users to search for jobs and read job descriptions like others have done, HotLizard offer a more advanced mobile website that includes the following:
Since the Gecko Mobile Website was launched, we have listened to our customers and have already improved the feature in line with this feedback. Gecko now detects whether the visitor is accessing the site via a handheld device and if so, they are automatically taken to the mobile version of the website.
For more information on HotLizard's products and service please contact: Claire Glover | email@example.com | 01635 527900 | www.hotlizard.net
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My latest makeup obsession, gold eyeliner, couldn't be more perfectly timed for the season. Its warm, metallic hue illuminates your face, feels festive and—because you apply it in one sleek line (not as a glittery free-for-all)—is totally versatile. You can wear it to the office or fancy cocktails and never look out of place.
Bonus: You don't have to be so precise when applying gold, because it's pale, neutral and reflective. With a shaky hand, I ambitiously trace Urban Decay 24/7 Glide-On Eye Pencil in El Dorado around my upper and lowerlash lines, then add some black mascara—it always looks great.
More on Luckymag.com:
- Holiday Makeup Palettes We Love
- Make Room for Fashion: Time to Sparkle
- Holiday Hair DIY: Glitter Bobby Pins
- Holiday Parties: Match Your Drink to Your Dress
- I Found My Perfect Red Lipstick, Courtesy of the J.Crew Catalog!
Keep up with the Lucky team on Twitter: Follow @LuckyMagazine


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Use folders to organize layers
Layers in a map can be organized into folders that hold similar or dissimilar layers. Map viewers can display the layers inside a folder as separate entities or as one unit, depending on whether you lock the layers together in the folder.
When you add layers to a folder, the folder appears on the Map details page in the list of layers. Two settings determine the way that map viewers interact with the folder's contents.
Visible? indicates whether the folder's layers and subfolders are visible on the map by default.
An open eye means that all layers and subfolders are visible by default. A closed eye means that none are visible by default. A dash means that there's a mixture of settings in the folder.
Locked? indicates whether a map viewer can display or hide layers in this folder and its subfolders as separate entities.
A lock image means that the layers are always treated as a single entity. A crossed lock means that a map viewer can display or hide layers independently.
Once you've created folders in a map, you can click the tree symbol at the top of the layer list to display the complete contents of the map, including the folder hierarchy and the contents of all folders and subfolders.
See Supported data formats and limits for limits on folders in a layer. There are no limitations on the following:
- the number of layers in a folder
- the size of a folder
- the number of folders to which a layer can be added
However, although you can put an unlimited number of layers into a folder, only 15 vector layers can be displayed on a map at any one time. Therefore, locking a folder that contains more than 15 layers makes the viewing client unable to display the contents, even if the folder is set to Visible.


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Cooper Pest Solutions: Workplace Giving Partner Spotlight
EarthShare New Jersey has had the pleasure of working with Cooper Pest Solutions, a progressive pest control company located in Lawrenceville, New Jersey. As a corporate partner in our workplace giving campaign, Cooper's employees make payroll contributions to their favorite environmental charities. The workplace giving campaign is a wonderful way to increase employee satisfaction while contributing to the enhancement of our natural surroundings and quality of life.
On January 29th we visited the Cooper Pest Solutions annual meeting and workplace giving kickoff event with our member organization Woodford Cedar Run Wildlife Refuge. The organization brought two very special guests, barn and screech owls named Otus and Squam, to meet the Cooper team. What a hoot had by all!
We recently interviewed Phil Cooper, President of Cooper Pest Solutions, about his relationship with ESNJ and why he supports a cleaner and greener New Jersey. Phil has served on the EarthShare New Jersey Board and Executive Board since July 2013.
What inspired you to rally the employees behind the EarthShare NJ mission?
Our corporation is committed to being a steward of the environment and has been for over two decades. Rick Cooper, Vice President of Cooper Pest Solutions, has been an ardent supporter of the New Jersey Environmental Federation, and as a corporation we have supported its initiatives for years. EarthShare New Jersey provides Cooper with the platform to show its commitment ensuring that we have a sustainable environment in New Jersey.
This year, some very special feathered friends attended your annual meeting. Tell us about how your employees enjoyed the experience and a few things they learned about owls. Was is it a hoot?
The owls were rock stars at the meeting and yes, they were a hoot. From what I gather, when our band Coop and the Stink Bugs rocked out so did the owls! Having the owls appear at our meeting added flair and excitement while drawing attention to the best that New Jersey has to offer. We'd love to have the owls join us again next year and if we get the chance we would integrate them more into the meeting.
How does your business benefit from participating in a workplace giving campaign?
Workplace giving provides an easy point of access to each of our teammates to make charitable contributions. By doing it as part of their job, it becomes part of their routine and makes it into a manageable expense. EarthShare NJ's Executive Director Paula Aldarelli provides us with whatever we need to ensure the success of the campaign, whether it be a kiosk at our annual meeting, links to the giving website or reporting on how our workplace giving campaign is performing. She also provides access to other charities that we wish to include in the program. I truly believe the workplace giving campaign is our chance to highlight the environmental causes in New Jersey and it's a wonderful platform to do so.
Are there certain environmental groups in the ESNJ family that you and your employees connect to?
The Clean Water Fund and the New Jersey Environmental Federation (NJEF) have been close with Cooper for years. Our relationship with Jane Nogaki, founding NJEF board member and Pesticide Campaign Coordinator, has developed over the last 20 years. I personally worked with Jane on many different issues to find common ground between my pest management industry and the positions taken from an environmental perspective. While we do not always agree on all of the specifics, we always agreed on the basic message or purpose and find ways to come up with solutions that benefit everyone involved.
Why is Cooper's bat removal service applauded by Conserve Wildlife Foundation of New Jersey? How do you think you'll collaborate with the organization in 2014?
Bats play such an integral part of the eco-system and we have been looking for environmentally sound ways of approaching them. I am first learning of the Conserve Wildlife Foundation of New Jersey and their bat removal services. I am excited about the opportunities the Foundation will afford and our ability to promote bat health in New Jersey to our customers and others. I truly believe the only boundaries are the limits of our creativity. I look forward to working with Conserve Wildlife Foundation and being a model for the state and perhaps the nation.
How can you and your employees influence others to give back?
My mother and father taught me the importance of giving back. My father was a Rotarian and one year after joining Cooper Pest Solutions in 1984, I also became a Rotarian. Being part of a Rotary exposed me to the countless causes throughout New Jersey and the world that need help. It also instilled in me our responsibility as corporate citizens. Over the years I was able to extend this to my passion to help organizations working to find a cure for Multiple Sclerosis. I have raised over $250,000 for the cause. This was taken to another level when I rode my bicycle cross country in 2012, with the Bike the US for MS team. I was able to rally my pest management industry around this cause and raise awareness. What has brought me so much joy is the recognition I have received from NJBIZ as the 2013 Corporate Citizen of the Year, which honored me and the Cooper Pest Solutions team for our pursuit of being great corporate citizens. I truly believe as great citizens we have a responsibility to promote diversity , raise awareness for causes, and help those in need.
EarthShare New Jersey is a perfect alignment of raising awareness for causes and allows us to not only promote a healthy environment, but also to raise funds to support the activities vital to a healthy environment. Being asked to serve on the EarthShare New Jersey Board and Executive Board is a great honor and responsibility. It is through ESNJ that I am able to show my commitment to a sustainable environment and show how a pest management company can be environmentally responsible.
Learn how your company can give a hoot about NJ's environment
If your business would like more information on becoming a corporate partner, contact Paula Aldarelli at 609-989-1160 or firstname.lastname@example.com. Follow us on Facebook and Twitter for updates on workplace giving, volunteerism and special events.
While Barred Owls are common throughout North America, they are considered a threatened species in New Jersey. They are common in wetland forests and can often be heard vocalizing during dawn and dusk. Eastern Screech-owls are found throughout eastern North America and common in New Jersey. They are a cavity nesting species and use holes in large trees for nesting. There are three color variations, red, grey and brown.
Barred owl photo courtesy of Woodford Cedar Run Wildlife Refuge


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Recipe For Carrot Soup
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The May issue of Women's Health has a feature on butternut using recipes from South African celebrity chefs. The four chefs that contributed their recipes are Reuben Riffel, Pete Goff-Wood, Luke Dale-Roberts and Margot Janse. I was offered the opportunity to blog … more ♥
I am busy reading through my copy of Tom Kitchin's first recipe book and slowly making my way through the recipes. It is a seasonal book, and as I have had it a year I am nearly done with the … more ♥