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Radiant in Commercial
Seattle restaurant provides ample food, comfort
The Seattle, Washington, Capitol Hill neighborhood is known for establishments that rely on posh and decadence, but the Mexican restaurant Poquitos has become a local favorite due to its combination of freshly prepared food and comfortable seating, according to the Puget Sound Business Journal.
Each seat comes with its own heater, while the restaurant features a radiant heating system that allows for customers to enjoy their burritos and tacos in a comfortable atmosphere.
A radiant heating system allows establishments to provide an efficient source of heat while minimizing the appearance of unsightly products like radiators and heating ducts.
The news source reported that the success of the restaurant - only six months old despite the already massive customer base - is a combination of location and culture.
"We knew from the population density and the foodie culture that it would hit the ground running," Rich Fox, general manager of the restaurant, told the Journal. "For Seattle, Capitol Hill is the best urban neighborhood. It's become a destination area. And some people who live here never leave the Hill. So you know people will be out for more than just the weekends."


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|The effects of high-intensity intermittent exercise training on cardiovascular response to mental and physical challenge.
MedLine Citation:
|PMID: 23220158 Owner: NLM Status: Publisher
|The purpose was to examine the effect of a 12-week exercise intervention on the cardiovascular and autonomic response of males to mental and physical challenge. Thirty four young overweight males were randomly assigned to either an exercise or control group. The exercise group completed a high-intensity intermittent exercise (HIIE) program three times per week for 12 weeks. Cardiovascular response to the Stroop task was determined before and after the intervention by assessing heart rate (HR), stroke volume (SV), arterial stiffness, baroreflex sensitivity (BRS), and skeletal muscle blood flow. The exercise group improved their aerobic fitness levels by 17% and reduced their body weight by 1.6 kg. Exercisers compared to controls experienced a significant reduction in HR (p < 0.001) and a significant increase in SV (p < 0.001) at rest and during Stroop and exercise. For exercisers, arterial stiffness significantly decreased at rest and during Stroop (p < 0.01), whereas BRS was increased at rest and during Stroop (p < 0.01). Forearm blood flow was significantly increased during the first two minutes of Stroop (p < 0.05). HIIE induced significant cardiovascular and autonomic changes at rest and during mental and physical challenge after 12 weeks of training.
|Mehrdad Heydari; Yati N Boutcher; Stephen H Boutcher
Related Documents :
|16107648 - Regular exercise prolongs survival in a type 2 spinal muscular atrophy model mouse.
23833198 - Benefits of physical exercise on the aging brain: the role of the prefrontal cortex.
23806438 - The effects of cardiovascular exercise on human memory: a review with meta-analysis.
24285938 - Effects of metoprolol and nebivolol on exercise blood pressure in patients with mild hy...
19053138 - Adaptation of the rat cardiac proteome in response to intensity-controlled endurance ex...
9445308 - Hyperventilation induces release of cytokines from perfused mouse lung.
Publication Detail:
|Type: JOURNAL ARTICLE Date: 2012-12-6
Journal Detail:
|Title: International journal of psychophysiology : official journal of the International Organization of Psychophysiology Volume: - ISSN: 1872-7697 ISO Abbreviation: Int J Psychophysiol Publication Date: 2012 Dec
Date Detail:
|Created Date: 2012-12-10 Completed Date: - Revised Date: -
Medline Journal Info:
|Nlm Unique ID: 8406214 Medline TA: Int J Psychophysiol Country: -
Other Details:
|Languages: ENG Pagination: - Citation Subset: -
Copyright Information:
|Copyright © 2012. Published by Elsevier B.V.
|University of New South Wales, Australia.
Export Citation:
|APA/MLA Format Download EndNote Download BibTex
|MeSH Terms
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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subset: commoncrawl


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Please help me with this.
I have now a new computer, with Windows Seven and stuff.
It has two directories of Programs (Programs and Programs (x86) ).
I managed to have sony vegas working, but Plug-ins (such as New Blue, SpiceMaster, etc) aren't, even with "tricks".
But the worst isn't that. The worst is that codecks and stuff about AMVaap won't appear either.
Solutions: Vegas was instaled at Programs, while everything else on Programs x86. I tried to instal at Programs x86, works but still with the same problems.
Any help please?


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Report of the Special Representative of the Secretary-General on the issue of human rights and transnational corporations and other business enterprises, John Ruggie. Business and Human Rights: further steps toward the operationalization of the "protect, respect and remedy" framework.
The policy framework rests on three pillars:
1. The State duty to protect against human rights abuses by third parties, including business, through appropriate policies, regulation, and adjudication.
2. The corporate responsibility to respect human rights, which means to act with due diligence to avoid infringing on the rights of others.
3. Greater access by victims to effective remedy, judicial and non-judicial.
Tags: Human Rights
Posted in FTA - EU Colombia, Official Texts


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The Sydney Morning Herald (NSW : 1842 - 1954)(about)
Previous issue Saturday 30 September 1911 Next issue
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TOPULAR SERGEANT-AT-ARiMS.,
Mr. Laurence Joseph Hnrnott, for many yoars ono of tho most familiar figures,,'.'it Parliament House, died yesterdny at ' his
resldonco, Cronulla.
His health had long hoon unsatisfactory, and it yvas because of this that a llttlo over two yoars ago ho resigned tho office of Sor goant-at-Ann8 in the Legislativo Assembly.
Mr. Harnett was born at Roaobrook, near Cooma, on Oetobor hi, 1842, and had thus reached the ago of CO years. Mrs. Harnett died many years ago, hut thero aurvlvo two sons and a daughter. One ot tho sons la a solicitor In tho Justice Department, and. the other is Clerk ot Papers in tho Legislativo Assembly, and has from time to time dis- charged the official du ti ob that his father yvas so long Idontlfled with.
Tho deceased gentleman Joined tho Par- liamentary staff in 1SG0, and In May, LS'i.t, was appointed Sorgeant-at-Arma, an office in which ho served for the long period of ,10 yoars. When announcing tbo resignation to I ho House In July, 1009, Mr. M'Court, who yvas thon Spoakor, Bald: "I feel sure I shall bo expressing the opinion of lion, members yvhon I say that on all occasions Mr. Harnett portormed the duties ot bis olllco, which fre- quently required firmness, tact, and judg- ment, with courtesy, and so as to command the respect and esteem of all concerned. I deslro also to placo on record my apprecia- tion ot his services and to express my deep rcgrot at his retirement, especially In view ot the causea yvhich havo rendered that step necessary. Mr. Harnett served under various Speakers from the time of Sir Terence Aubrey Murray, and I believe they all expressed high approval of the manner lu yvhich ha per- formed his duties. I believo this approval Is shared by the outside public, to yvhom In Ibu performance of lils duties at Pnrliumont House ho waa ever considornto and obliging." Tbo House, hy resolution, placed Mr. Har nott's letter of resignation, and tho Spoalcor's remarks, upon tho permanent records.


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Build a bare metal server with your choice of processor(s), hard drive configuration, RAM, port speed, and more.
Select the cores, storage, and RAM you need in your virtual server, and we'll deploy it in 5 to 15 minutes.
Scale your storage infrastructure on demand while controlling your costs with SoftLayer object storage.
DALLAS AND MENLO PARK—Aug. 3, 2010
SoftLayer Technologies®, the innovative on-demand data center services provider, today announced a transaction in which its management team and GI Partners, a private trans-Atlantic investment firm, have acquired all of the equity in SoftLayer.
Since its founding, SoftLayer has revolutionized hosting through its unswerving commitment to innovation and automation. At a pivotal time in the industry, as increased connectivity, virtualization advances, and cloud service innovations dramatically reshape the landscape, SoftLayer is poised to continue playing a significant role in the industry's transformation.
"I'm extremely proud of how much SoftLayer has grown and accomplished in its history. GI Partners' investment and partnership enables us to take our unparalleled approach to the next stage," said Lance Crosby, Chief Executive Officer of SoftLayer. "It's gratifying that a firm with GI Partners' insight and success sees such value in SoftLayer's past growth and future opportunities."
"SoftLayer has taken a visionary model and created a company for the future of hosting," said Rick Magnuson, Executive Managing Director of GI Partners. "We are excited to bring additional resources and experience to help SoftLayer leverage its strategic position in the expanding global data center services market."
DH Capital served as exclusive financial advisor to SoftLayer in connection with the transaction.
Headquartered in Dallas, SoftLayer is the innovation leader in Cloud, Dedicated, and Managed Hosting, and the largest private hosting company in the world. SoftLayer provides cloud, dedicated, and seamlessly integrated computing environments, with world-class data centers in Dallas, Houston, San Jose, Seattle, and Washington D.C., and network Points of Presence nationwide. The company integrates and automates all elements of its platform, empowering enterprises of any size with complete control, security, scalability, and ease-of-management via a leading Customer Portal and Open API. For more information, please visit www.softlayer.com or call 866.398.7638.
Established in 2001, GI Partners is a leading private investment firm that focuses on control-oriented investments in asset-backed businesses and properties located in North America and Western Europe. The firm is active in a number of key sectors, including asset-backed IT services, specialty healthcare and education, leisure, commercial real estate, hospitality, retail and financial services. Since inception, the firm has secured $4 billion of capital commitments from recognized institutional private equity and real estate investors in the U.S., Europe, and the Middle East. It is currently investing from GI Partners Fund III. For more information, please visit www.gipartners.com.


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Email communications to the firm through this website will not create an attorney-client relationship between you and the firm if one does not already exist. Please do not send any privileged or confidential information to the firm though the website.
Click below to confirm that you have read and understand this notice and to send the email.
Copyright © 2015 Morvillo Abramowitz Grand Iason & Anello PC
Jasmine Juteau specializes in representing individuals, corporations and non-profit entities in white collar criminal investigations and trials, enforcement actions and complex civil litigation.
Jasmine has substantial experience litigating in federal and state courts on criminal and civil cases. She has federal criminal trial experience and has defended cases alleging securities fraud, accounting fraud, mail and wire fraud, civil RICO and related issues. Jasmine was on the team that successfully represented Afshin Mohebbi, former Qwest Communications President and COO, winning a complete dismissal of the SEC's claims against him. She has also represented numerous public companies in various phases of class-action securities litigation. Jasmine has defended clients under investigation by the Department of Justice, the District Attorney's Office, the SEC, the CFTC, FINRA and various other federal and state authorities. She has handled a wide variety of investigations, including alleged fraud, insider trading, market collusion, internal controls violations, disclosure violations, rogue trading and illicit trading fees.
Jasmine also focuses on independent corporate compliance oversight. She has participated in an FCPA monitorship, provided legally-mandated integrity oversight for a horse racing entity and performed independent verification for several banks participating in the Department of Justice Program for Non-Prosecution Agreements or Non-Target Letters for Swiss Banks.
Jasmine was named a 2014 "Rising Star" by Thomson Reuters' Super Lawyers. She is a member of the New York City Bar Association where she served as the Secretary of its African Affairs Committee for eight years, and is also a member of the New York Criminal Bar Association.


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What is [0x1] Iray® For Maya®?
IrayForMaya is the integration of Iray into Maya.
What is NVIDIA® Iray®?
Iray is the first GPU-accelerated solution for physics-based, photo-realistic rendering world-wide. Combined with the parallel processing power of the latest NVIDIA® video processors, Iray achieves interactivity with extremely fast reactions and significantly accelerates the iterations required to create perfect scenes. For a detailed description of Iray please visit NVIDIA ARC's website.
Isn't Iray automatically included in Maya after I install mental ray®?
The basic technology of iray is included in mental ray, but it does not have the full functionality. [0x1] integrates Iray as an independently available renderer in Maya.
Does [0x1] IrayForMaya support NVIDIA's Material Definition Language (MDL)?
Materials defined using MDL are supported. For a description of NVIDIA's Material Definition Language please visit NVIDIA ARC's website.
What are the advantages of an independent Iray integration for Maya?
The seamless integration in Maya places Iray at your disposal as a renderer suitable for production with all its advantages and features in Maya. The interactivity and scalable architecture are surely interesting to users with regard to using different CPUs and GPUs.
Which operating systems will [0x1] IrayForMaya be available for?
[0x1] IrayForMaya is available for 64-bit-Windows and 64-bit Linux.
What hardware do I need in order to use [0x1] IrayForMaya?
Basically, [0x1] IrayForMaya functions on all computers that can be used to run Maya. Utilizing the advantage of GPU support locally requires an NVIDIA® video card with at least 2 GB of video memory.
What is a [0x1] IrayForMaya local workstation license?
This license is meant for individuals to access and use [0x1] IrayForMaya. A local workstation license will run on one single workstation with up to 3 render resource licenses and can't be transfered to another computer. It enables you to use three render resources on your local workstation. The resources are always the CPUs and two additional graphic cards.
What is a [0x1] IrayForMaya floating workstation license?
A floating workstation license supports the use of [0x1] IrayForMaya up to a maximum number of users or "seats", who are connected to a server network. The products can be installed on as many computers as desired; however, at any one time, can only run on the maximum number of computers for which licenses have been purchased. Because you can install the products on more systems than the number of licenses purchased, you get true floating licenses across your entire network. Each floating licenses comes with 5 render resource licenses. Each render resource license can be used by any computer connected to the floating license server.
What is a render resource?
A render resource is a unit that is used to calculate the image. All CPUs in one machine are one render resource. Each graphic card, that is detected by Iray, is one render resource. For each render resource you need one render resource license. A render resource license is always a floating license. The only exception are the render resource licenses coming with a local workstation licenses. These licenses can't be used in a network.
Is a trial version for IrayForMaya available?
A free trial version of IrayForMaya is for a 30 day period available. The trial version covers the full feature set of the software and needs Maya 2015. Currently the trial version is only available for Windows operating system. The usage of the trial version for commercial production is not allowed.
You can download the trial version here.


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Location: Mosquito and Fly Research Unit
2012 Annual Report
The objective is to develop and evaluate digital thermometer/relative humidity recording devices which have remote downloading capabilities and software adapted for predicting selected insect breeding cycles. Digital thermometer/relative humidity devices have been developed by the University of Florida (UF) for laboratory and field applications and will be evaluated by comparison to conventional equipment. Devices will be placed in selected locations and monitored for overall performance by the Agricultural Research Service (ARS). Applicable software has been developed by UF and appropriate transmission range will be determined by UF and ARS. Software is being incorporated in the modules by UF to predict the breeding speed of selected insect species. This project is moving slowly because of lack of funding, however field-ready models will soon be ready for evaluation.


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- Filed Under
By now most of us appreciate Amazon.com's delivery-by-drone scheme for what it was - a brilliant publicity stunt timed perfectly with the Internet's biggest shopping day, Cyber Monday.
It's nice to know a little Buck Rogers gee-whiz naivete still exists, but the episode also illustrates the electronic retailer's economic power. Not yet 20 years old, Amazon is a major corporate presence in Indiana and has dictated online sales tax policy here the past two years.
Amazon is interested in using drones to deliver packages someday and its seven Indiana fulfillment centers make our state a good ...


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The sentencing date for a former El Paso man who admitted to bilking a New York City madam out of thousands of dollars has been rescheduled yet again.
Jonathan Shoman, 34, who was nicknamed "Muffin Man" in a federal criminal complaint affidavit, was scheduled to be sentenced by U.S. District Judge Kiyo A. Masumoto in Brooklyn, N.Y., on Monday. However, court records show Shoman's sentencing date has been postponed until May 29. This is the fourth time Shoman's sentencing date has been rescheduled.
Shoman pleaded guilty in July 2012 to a federal information document charging him with money laundering. Federal prosecutors are also asking for $76,910 in restitution to be paid by Shoman.
Shoman was arrested in El Paso in January 2012 on allegations he fraudulently posed as a CIA agent in order to run background checks for the madam, identified in a separate case as Naira Jalovian, a Russian-born U.S. citizen who pleaded guilty in 2011 to racketeering charges.
According to court documents, Shoman told Jalovian he was a CIA agent who could conduct background checks on Jalovian's clients to help her avoid arrest and prosecution. In actuality, he spent more than $2,000 on two websites that offer background searches of individuals for a fee. Shoman never worked for the CIA.


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The Magazine
Gen. 'Stonewall' Holder
The Obama Justice Department—most opaque ever?
May 10, 2010, Vol. 15, No. 32 • By JENNIFER RUBIN
When I listed a number of conservative outlets already following the story, he invited me to submit citations to news stories. Kovakas explained, however, that the request was already "at the head of the line," meaning it was being treated as expeditiously as they could.
I spoke again to Kovakas in late February, and he explained that the request was out to lawyers for all recusal documents. He could give no time frame for their responses and explained there was no database or computer record of this information—just discrete documents. He then conceded that in light of the controversy generated in the media, the matter had become pressing. Still this didn't change the timeline which was, he explained, dependent on when they got the documents back from the very attorneys at issue in the request.
Nearly a month later Kovakas called and said they were "diligently working on this request." He could, though, not "explain why it is taking so long." He continued, "Don't take this to the bank but I think the end of next week. I met with a bunch of people last week and said I was very unhappy with how long this is taking. They asked a bunch of dumb questions." He added, "We take FOIA very seriously and appreciate your patience."
In April, I received 52 pages of documents from the civil division. They proved illuminating.
In a memo dated May 26, 2009, Tony West, the assistant attorney general heading the civil division—who had represented American al Qaeda member John Walker Lindh and whom Fox News had in March identified as one of the former detainee attorneys—recused himself from cases in which he or his firm had been involved, including al Qahtani v. Obama and a case concerning a Boeing subsidiary alleged to have transported detainees to CIA facilities (Mohamed v. Jeppesen Dataplan). Yet an earlier email, dated May 3, 2009, states, "Tony West has been cleared to participate in the management of the GITMO cases, except with respect to decisions relating specifically to . . . Al Quhtani v. Obama . . . given that Tony W.'s former firm continues to represent the detainee in that case." Presumably, for more than three weeks he worked on cases like Jeppesen from which he was subsequently recused.
There is no evidence in the documents that anyone systematically examined whether West should have recused himself from any policy decisions or from dozens of other highly controversial cases that might have directly impacted his former clients. Ed Williamson, a former legal adviser to the State Department who has written extensively on ethics issues, says, "The most charitable explanation is that they didn't spot the issue."
On August 28, 2009, West along with two other attorneys declared that they could no longer participate in seven cases in which Lindh was a witness, raising the issue whether their participation up to that point had been appropriate. As Williamson notes, "If it was a problem in August, it was a problem in May." What about cases potentially related to Jeppesen or al Qahtani or with common witnesses? No evidence of recusal from those has been produced. Again, no one seemed to spot the issue.
This muddle is in marked contrast to the actions of a former partner of West's, Beth Brinkman, who was selected by West as his deputy to head the appellate branch. In repeated emails, she made it clear that she should be recused not only from her former firm's cases but also from any related issues. In multiple emails in 2009 and 2010 she informed other attorneys who persisted in sending her materials to review that she was (as she wrote on August 3, 2009) "recused from Guantánamo matters." From documents made available to date, it does not appear that any other attorney took her position.
Other attorneys in the civil division who came from firms that represented detainees—such as Brian Martinez (West's chief of staff), Geoffrey Graber (counsel to the assistant attorney general), and Ian Gershengorn (West's deputy in charge of the Federal Programs Branch, which handles habeas petitions)—recused themselves from individual cases where their former firms represented detainees. Gershengorn, however, continued to play a role in setting policy on issues relating to his prior cases. In an email dated July 14, 2009, he wrote, "I have realized that, while I can discuss policy issues arising from substantial support etc., I cannot work directly on the brief because it is one of the Boumediene cases, and Jenner had an amicus brief in that case." (This begs the question of who, if anyone, was supervising the habeas petitions and the matters from which the political appointees were recused.)
The documents also confirm that the employment of ferocious advocates for detainees is not limited to the Justice Department. The State Department hired Columbia University law professor Sarah Cleveland. Columbia boasted in its announcement, "She will advise the State Department and the executive branch on international law issues, and will help develop the State Department's position in U.S. litigation involving international and foreign relations law issues." Cleveland filed an amicus brief in Boumediene, testified that there was no category of detainee "too dangerous to be released" (not even Holder agreed with that), and questioned the "power to detain persons seized outside a traditional theater of combat."
Cleveland also weighed in on the brief in a case identified as ACLU v. DoD in May 2009 (most likely the issue of release of detainee abuse photos) and invited Beth Brinkman to do the same. Brinkman firmly declined. But with figures such as Cleveland advising the administration, we can see how Obama received the advice that he had no choice but to release the detainee abuse photos. It is hard to escape the conclusion that the government was receiving, as one might expect from those who passionately defended detainees, advice sympathetic to those detainees.
The limited information the Justice Department has so far released raises real concerns as to whether former advocates for detainees were properly recused from matters involving Guantánamo detainees and policy decisions that would inevitably involve their former clients. Did they violate obligations to former clients by construing their recusal obligations too narrowly? Did they damage their current client, the United States, by shading their advice for the sake of consistency with their prior representation?
Professor Richard Painter, an ethics expert from the University of Minnesota, wrote to Holder in April raising such issues. He noted, "There are legitimate concerns about client conflicts for lawyers who previously represented detainees and now work for the Department." The "simplest" approach he advised would be to have them recused from all detainee matters. If they aren't, he cautioned,
The professor noted that the ABA Model Rule 1.9 requires Justice to examine if other matters are "substantially related" to the exact ones in which the attorneys appeared, an analysis made difficult with the government itself taking the position "that some of these detainees have been acting in concert with other detainees."
At least with respect to the civil division—the only one that has yet lifted the veil of secrecy—it appears this was never done. West and his former law partners (except Brinkman, who seems to take Painter's view) simply listed and recused themselves from cases on which they or their former firm represented detainees. There is no evidence that anyone considered whether the scope of that recusal should have been far broader.
In an interview, Painter explained that there are multiple risks for these attorneys. "One danger is that you give an issue to the detainee who is convicted. Another is that you actually disclose information [you obtained] from a former client. A third is that the lawyer in an effort to avoid one and two bends over backwards by underrepresenting" the United States. Clients (even the government) have a right to be fully represented.
The administration's defenders contend that many lawyers in private practice, antitrust specialists particularly, go into government and litigate in areas they previously practiced. The Guantánamo situation, however, is different in three key respects.
First, this administration had promised to avoid unseemly sideswitching and passed a specific ethics policy to prevent even the appearance of impropriety. Second, the national security stakes are much higher, and any risk of reversing a key conviction is a danger. And finally, unlike an antitrust lawyer who can litigate thousands of cases without implicating a former client, the universe of Guantánamo detainees is so small and interrelated that it is virtually inevitable that policy advice or decisions in one case will have direct implications in another. If there was any doubt, a Bush administration appointee who left the civil division was instructed by the Obama administration that he must recuse himself in private practice from all Guantánamo matters, not merely the specific ones he worked on. It seems that going out the door the Obama team recognized the potential conflicts for former Bush officials, an issue which escaped their notice for incoming Obama appointees.
It is also noteworthy that the Office of Government Ethics has copies of waivers allowing three Justice Department officials (Holder, former Deputy Attorney General David Ogden, and Assistant Attorney General for the Criminal Division Lanny Breuer) to work on Senator Ted Stevens's corruption trial. No such waivers appear for any Justice official for Guantánamo matters.
Serious concerns remain whether the Obama Justice Department attorneys, including the attorney general and his closest advisers, complied with the full extent of their ethical obligations. Given the stonewalling by the department, it is difficult to be confident the American people are receiving the robust representation to which they are entitled. We may have to wait for FOIA responses to finally trickle in or for future litigation to find out whether attorneys in the administration inadvertently gave their former clients new defenses against the United States. Or can the Obama administration be pressured into—at long last—fulfilling its promises of transparency.
Jennifer Rubin is a contributing editor to Commentary magazine.
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Pic Of The Day
British riders cycle in line during a training session at the Velodrome in Athens three days before the start of the cycling track competition at the 2004 Olympic Games
A Worldwide Support Network For Chronic Myelogenous Leukemia
British riders cycle in line during a training session at the Velodrome in Athens three days before the start of the cycling track competition at the 2004 Olympic Games
Biomed boost from Swiss giant
Novartis's $310m investment in a drug plant will help Singapore's push to be a centre for high-value pharmaceuticals
IN A major boost to Singapore's fledgling biomedical sector, Swiss pharmaceutical giant Novartis is making its biggest investment in Asia, by building a drug plant here at a cost of US$180 million (S$310 million).
Novartis, the world's fifth-largest seller of prescription drugs, with sales of US$25 billion last year, said yesterday that when fully operational by 2008, its new Singapore facility would create more than 150 jobs.
The announcement is the latest boost to Singapore's ambitions to become a strategic centre for the production of high-value pharmaceuticals.
The Republic is promoting the fast-growing biomedical sector as a key pillar of the country's all-important manufacturing sector and has set a goal of achieving output of $24 billion over the next decade, as well as providing 15,000 jobs.
And the industry is well on track, with output expected to hit $12 billion this year, a year ahead of schedule.
Novartis Pharma AG's new pharmaceutical production facility will be built in the Tuas biomedical park and will focus on the bulk production of Novartis products, such as anti-hypertension drug Diovan and abdominal discomfort treatment drug Zelnorm.
It will also produce Gleevec, a new cancer drug, which is one of the company's leading revenue drivers.
'The new Singapore facility will enhance and complement our existing network of pharmaceutical production plants by producing tablets for the global market,' said the head of Novartis Pharma Technical Operations, Dr Andreas Rummelt.
'We have been under-represented in Asia… As we needed more capacity to meet growing global demand we looked at several locations like Singapore, India and China,' he said in a phone interview from his Basel office.
'Singapore is an ideal location for us,' he said, citing the Government's strong support for the sector, intellectual property protection, political and economic stability, and the availability of scientific expertise as some of the Republic's attractions.
Dr Rummelt said that construction of the plant is expected to begin towards the end of the year, with operations beginning in 2007.
Yesterday's announcement follows the opening last month of the US$122 million non-profit Novartis Institute for Tropical Diseases in collaboration with the Economic Development Board. And Novartis' CIBA Vision business unit is in the process of building a contact lens manufacturing facility here.
Two key Novartis' rivals also announced moves here recently.
Last month, United States-based Pfizer, the world's biggest pharmaceutical company, unveiled a new $600 million plant just after closest rival, Britain's GlaxoSmithKline opened another facility, taking its total investment here past S$1 billion.


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There is a lot of consideration that goes through the whole process of Middle East web design. This is because more than just an online platform for the business, it has the potential of improving business fortunes. With so many people carrying out trade online, a good website can just be the asset you need in your business to increase the sales. However, when handled with little regard, a small mistake could have the whole brand and image of the business tarnished. You could also end up missing the whole benefits that website design Middle East affords.
There are four major things that you can use to make the most out of your website. Firstl, when it comes to web design Middle East, you will need to know just what you need for your business. This is important because it will allow you better explain to the various companies dealing with web development Middle East what you want. You can check the websites of a number of companies and also talk with an expert in web development Middle East. This way you will get a clear picture and thus see that your needs are met by the designer. It will also give you knowledge on a number of factors that count when it comes to web design Middle East.
You will have to know the number of pages, images, and other technicalities. These are important as they also determine the fee you will be charged for your website. Having known your idea, the next thing is finding the right web design Middle East company to execute your plan. The Internet offers a great place to do your search. You should search extensively and can check for their reviews or use referrals on the best service available. You will also need to check the portfolio of different web design Middle East services. Comparing the costs and discounts or free services will also help in picking the right web development Middle East deal.
The third most important factor that will help in the effectiveness of your website is the additional features. These include entry pages, social media connection, and other sites or even have poll features added. When it comes to web development Middle East, making it as interactive as possible is crucial. You will also have to focus mainly on a customized website. This allows your website to stand out amongst others. Web development Middle East is about increasing your edge over competitors so a little ingenuity will always get you ahead.
Lastly, you have to combine a number of Dubai SEO methods for the success of your website. When undertaking web design Middle East, decide which ones will work for you after consultation and use them. This will help you get a higher ranking and have a professional outlook from the content to the creation of links leading to your site. Web development Middle East needs to be undertaken after all factors have been considered. The selected design should allow for easy changes in future.
iBaroody is the author of this article on web design Iraq. Find more information, about web design company Baghdad here


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Dry eye occurs when the eye doesn't produce enough moisture to keep itself protected and comfortable. Some people suffer from chronic dry eye, brought on by aging or simply an imbalance within the eye. However, those of us who work in front of a computer all day may suffer from dry eye from time to time. When we focus intensely on one thing for a while, we don't blink as often. Blinking is what keeps our eyes lubricated. You can avoid dry eye by remembering to blink, avoiding eyestrain, and using moisturizing eye drops. If you feel yours is a chronic condition, visit your doctor to find out about further treatments.
Facts About Eyestrain
It's unlikely that watching too much television, reading too many books or staring at a computer screen will permanently damage your eyes. However, all of these activities can cause eyestrain, which isn't something you should ignore.
Eyestrain is when your eyes get overtired from too much use. You can get eyestrain from watching television in a dark room, excessive computer use or even driving. Reading in dim light can contribute to eyestrain as well. Any time you intensely focus your eyes on something for a long period, you're at risk for eyestrain.
Symptoms of eyestrain include:
- Headache
- Sore, burning or itchy eyes
- Tired eyes
- Watery eyes
- Dry eyes
- Temporary blurred or double vision
- Light sensitivity
- Trouble focusing between paper and computer monitor
- "Afterimages" when you look away from the monitor
Eyestrain is a short-lived condition that you can treat yourself. For most people, the treatment simply is to rest your eyes. Take regular breaks from intense focus -- about five minutes each hour. Blink often to keep your eyes moist.
If your eyes are dry, try some over-the-counter artificial tears to re-moisten them. Also, ensure your glasses or contact lenses are appropriate and up-to-date for your needs. You can even buy some that are specially suited for computer work.
To prevent or minimize future eyestrain issues, you can make several changes to your work and home environments. Here are a few tips:
At work:
- Keep your monitor about an arm's length away.
- The top of your monitor should be about eye level or below. You should look slightly down in order to read the monitor.
- Take steps to reduce glare -- turn off bright overhead lights or close the blinds.
- Make sure your keyboard is directly in front of your monitor so your eyes don't have to work too hard.
At home:
- When knitting, sewing or performing other up-close work, ensure your light is bright enough and shines directly on your work.
- While reading in a chair, the light source should come from behind you and shine directly on the page.
- Keep the room lighted softly while watching television or DVDs. Too much contrast between the screen and the rest of the room can make your eyes work too hard.
For more on television and eyestrain, look at the links on the next page.


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Whether it's a club record signing or a bargain basement Bosman there is always some value to be had in the transfer market.
A news article on 2012-05-08 23:01:39 from: The Mail
This news item has been reproduced from today's media. It does not necessarily represent the opinion of Kop That.


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Mamatography 2012: And So It Begins…
|January 4, 2012
|Posted by Luschka under Mamatography, Projects & Series
I'm thrilled to share with you the startling line up (and… that's as far as my 'get more sporty' resolution for this year goes!!) for the first ever Mamatography challenge at Diary of a First Child.
Every Wednesday you'll see our week in pictures, and below the post will be a link up where these lovely ladies will be adding their weekly posts too.
Mamagtographers, no one expects you to visit each of your fellow challenger's posts each week, but it would be great if you could stop by the post of the person who linked up before you, and leave them a comment. If you have the time and inclination to do so for more then please do!
If you'd still like to join us, you can start at any time, just sign up here and I'll email you further information.
If you'd like posts on Mamatography delivered to your reader or your inbox, sign up to our Mamatography only RSS feed! (If you're already a subscriber, there's no need to do this – you'll get it automatically.)
Without further ado, here is the current list of all participants for Mamatography 2012 so far!
- Michelle at Woman of the Willows and Wetlands
- Cristin at From Cristin To Mommy
- Lucy from Princess poet's Life Adventures
- Kat from Loving {Almost} Every Moment
- Shannon R who writes at The Artful Mama
- Amanda from The Family Patch
- Jorje of Momma Jorje
- Sarah, a regular reader here, who writes Boo Roo and Tigger Too
- Kelly from Becoming Crunchy
- Christine, my South African AP friend (yes, just the one!) writes the fantastic African Babies Don't Cry blog
- Melissa from Vibrant Wanderings
- Actually Mummy… with her blog, Actually Mummy…
- Megan from Boho Mama
- Caryn at Casyfamily
- Gauri Ma from Loving Earth Mama who will be playing along here, and on Flickr
- Paige from the fantastic blog Baby Dust Diaries
- Megan of The Mommy Metamorphosis
- Lani at Boobie Time
- Amy Willa who writes Toddler In Tow
- Heather from Mama Unfurling
- Hannah writes at Attached Mommyhood
- Sarah from Adventures of the Raanan family
- Rachelle, author of Mommy and Little I
- Sheila of A Living Family
- Avital from Fun with Ima (mommy)
- Shari at ShariMamatography
- Toni Carrigan from Carrigan's Joy
- Marcy Prochaska at Becoming Three
- Angela who is looking to take more pictures
- Susan from Girls Can Do Anything
- Amy from Anktangle
- Emily, author of Growing A Life
(If you want to link up photos for the 1st – 3rd of Jan, do so below, but week 1 will officially be next week…)
30 Responses to Mamatography 2012: And So It Begins…
[…] am so excited to be a part of Mamtography 2012: Capturing Each Moment . I hope to collect a year's worth of photos to display here as well as our family photobook. […]
[…] still going strong with my 'Mamatography' 365 challenge. Lovin' it, too. I have said before I find it hard work because of my […]
[…] Week 3 of the Mamatography 366 (photo-a-day for a year) project. I am doing this to push myself, to build my photography skills, keep a record of the year and have fun. Won't you join us? Sign up here if you are up for the challenge. […]
[…] two of this 366 photographic adventure kick-started by Luschka at diary of a first child. If you've got a blog, a baby and a camera you can join in, too (actually the blog is […]
[…] super excited to be taking part in Diary of a First Child's Mamatography Project. These are the first week's efforts. Hopefully this will help me improve my photography […]
What a wonderful idea. I'm in.
Outdoors Mom's last blog post ..Unscheduled Time
Luschka Reply:
January 9th, 2012 at 9:26 am
Excellent! We're happy to have you! Please remember to complete the sign up sheet: http://tinyurl.com/mamatography
Outdoors Mom Reply:
January 9th, 2012 at 10:47 pm
Outdoors Mom's last blog post ..Mamatography 2012
I find it fascinating that we have at least 5 countries among us. USA, UK, NZ (I think), Israel, and South Africa.
Hannah's last blog post ..Mamatography – First days of 2012
Thank you! My first week is in!
Actually Mummy…'s last blog post ..It's 366 Sunday
oh my word! I'm so excited about this! this week has shown me that I don't like my iphone camera! the resolution sucks!hmm.. going to check out the others but won't link up till wed!
Lucy's last blog post ..Looking back: Ethan's Birth Story through Hubby's Eyes.
Lucy Reply:
January 8th, 2012 at 8:39 pm
I ended up linking today!
Lucy's last blog post ..Mamatography Week 1 ( Day 1-7)
Kesia Reply:
January 10th, 2012 at 3:08 pm
Thanks so much for sharing a view into your world with us! I enjoyed my stay.
Kesia's last blog post ..A Mamatography Challenge – Week One
Here is our first week. Love everyones pictures so far.
Hannah's last blog post ..Mamatography – First days of 2012
So impressed by the line-up. Well done you for reaching out and 'reeling them in' – hahah. Awesome. So much fun.
[…] the creative process up anymore… But now I am so ready. Imagine my delight when Luschka of Diary of a First Child put out a challenge to other mother bloggers to join in a new venture of hers she is calling […]
Super excited about the project – I'm posting this weekend from the partial week.
angela's last blog post ..fun with string
Ive started already
Going to go check out a few of the other participants photos now!
Christine @ African Babies Don't Cry's last blog post ..Mamatography Photo Project : Week 1
I went ahead and started with the partial week — there's likely going to be food, a kid, and who knows what else in my year's pictures.
Marcy's last blog post ..Mamatography Week 1
Looking forward to it! And to your notes giving me a kick up the backside to actually do it
Actually Mummy…'s last blog post ..Highs and Lows 2011
Thanks again for hosting this challenge and the linky!
Amy's last blog post ..Photo Challenge: Week 1
I'll be linking up next week. My plan is to do Sunday – Sat, post on the following Sunday, then link up on the following Wed. Therefore, for the first week, I'm taking photos from Jan 1-7, posting on the 8th, then linking that post on the 11th.
I can't wait to see what people come up with as far as themes. Right now, I'm just taking photos all day, then picking the one thing that happened all day that sticks out the most to me. But there are so many amazing and creative possibilities for this project!
Alicia C.'s last blog post ..What We Did Last Week {Wordless Wednesday}
Luschka Reply:
January 4th, 2012 at 8:53 pm
That sounds like a great plan Alicia. I was considering doing the same, but in the end stuck to my Wednesday to Wednesday format – I don't want to mess with what I remember
I think your idea of 'what sticks out the most' is perfect, and definitely the right spirit of the Project. My camera broke and I'm positively dying without a 'decent' camera at the moment – I feel so limited in my photo-take-ability!
What a great group! Definitely looking forward to seeing how this project turns out for all of us – thanks for the inspiration Luschka!


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Your summer doesn't have to lazy. We found events for everyone: art fanatics, nature freaks, music lovers, history buffs, film-goers and sports nuts.
Click on a month below to explore the 80+ events we gathered for your convenience.
So invite some friends, bring your families, grab your dogs and enjoy Columbia in the summertime, where the livin' is easy. We'll see you out and about — if we aren't cooling off inside with a frosty drink, that is.
Written by: Paul Albani-Burgio, Winn Duvall, Dominique Feldman. Laura Heck, Christine Jackson, Alicia Kortendick
Illustrations by: Lauren Elliott


text: In Japan, where wasting food is tantamount to heresy, they've taken this humble upcycling of stale bread and turned it into a culinary craze. But rusk is ridiculously simple to make at home and not only does it prevent waste, it makes for a delicious teatime snack. Head over to PBS Food for the lowdown.


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Find more info HERE for the 2015 Collegiate Club National Championships April 24-25 in Clemson, S.C.
Collegiate Committee
The USA Triathlon Collegiate Committee is the working group of USAT Collegiate Triathlon, tasked by the Board of Directors to develop, administer and promote collegiate triathlon throughout the United States.
The Collegiate Committee directs and administers the policies to be implemented at the Conference-level and at the Collegiate National Championship. The Committee also works to increase the awareness, development and growth of triathlon at the collegiate level in each of the 10 USAT regions.
For more information about the Collegiate Committee, please click here.
Recruitment Program
The Collegiate Recruitment Program's goal is to expose collegiate swimmers and runners, who have both a background in the other sport and are finished with their eligibility, to the possibility of making a career out of triathlon. Through mentoring them on the steps and skills needed to becoming an elite triathlete, the program's goal is to identify talent from the NCAA ranks and fast track their growth in triathlon. For more information about the Collegiate Recruitment Program and to view the USA Triathlon Performance Pyramid, please click here.
Important Links
Internet Activities and Student-Athlete Involvement - Learn some of the best practices for education of student-athletes and policy development surrounding the ever-growing use on internet social sites.
Janet Judge, Sports Law Associates
Hazing Policies - This session will explore the dynamics of hazing within athletic teams and identify strategies for effective prevention and intervention, including policy formation, education, accountability, and non-hazing team-building
Collegiate Triathlon Conferences
There are 10 USA Triathlon Collegiate Triathlon Conferences that are affiliated with the USAT Collegiate program. These 10 regional conferences lead collegiate clubs through local events and programs designed specifically for collegiate athletes. Each Collegiate Conference maintains a page containing results, schedules and additional information. You can find the conference in your area using the map below or choose a conference from the links at right.
The sport of triathlon has seen a tremendous amount of growth over the past five years especially within the college and university community, resulting in a steady increase in the number of participants and schools at this level. This growth is expected to continue and has demanded the development of new programs supporting the growth of the college-aged triathlon community.
USAT Collegiate Multisport Development
USA Triathlon welcomes all colleges and universities to register their multisport club with USAT. By registering, your club will have access to resources available only to USAT registered clubs, including optional insurance coverage, grant opportunities, sponsor discounts, regional and national club competitions, and resource guides to help your club grow and succeed. To register your club, please click here.
Get Others Involved
The greatest encouragement to new members is the camaraderie and team support offered by the clubs and the healthy lifestyle advantages that multisports have to offer. It's great for your health, fitness, cross training and stress reduction. Multisport training often leads to expanding your social circles and leads to a positive sense of accomplishment.
For cross training, try some non-traditional, but very popular, distances and disciplines.
Triathlon: swim-bike-run
Aquabike: swim-bike
Aquathlon: run-swim-run
Duathlon: run-bike-run
Off-Road: swim - trail riding and running
On-Road: road riding and running (or multi-purpose pathways)
Winter Triathlon: run-mountain bike-ski (all on snow)
Indoor: pool-stationary bike-treadmill
There are various combinations of competitions, from splash-n-dash (swim-run) to formula 1 (run-bike-run-bike-run), so be creative. Mix it up between training, nutrition, healthy living and socializing to keep people interested and coming back year after year.
USA Triathlon offers an extremely successful coaching certification program and lists all current certified coaches here. Coaches may be available for full-time positions, part-time positions or special engagements and presentations for your club.
Community Involvement
One of the easiest ways to increase your clubs budget is to put on an event in the community. As an example, multisport clubs can organize a community aquathlon (run-swim-run) and collect registration fees to increase their budget for activities such as traveling to nationals as a team. For more information to put on and sanction your event, please click here or contact firstname.lastname@example.com
Don't wait any longer. For information on clubs and program development, review the information on the Clubs homepage or contact firstname.lastname@example.com.
For a complete listing of Collegiate Clubs, please click here.


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Stay In Touch
© 2011 Roland Michener Secondary School
Roland Michener Secondary School
155 Legion Dr
South Porcupine, ON
Phone: 705.360.8056
Fax: 705.360.8057
Email: email@example.com
Our School….R.M.S.S. …. home of the Green and Gold, the Rams & the Rebels since 1968!
Roland Michener is a community school with a commitment to excellence. Our dedicated staff focus on preparing students for life after high school which includes college, university or world of work.
Roland Michener is a French Immersion school that offers dual credit opportunities and also offers a Level 1 Construction Apprenticeship in partnership with Northern College.


text: Bright green petals and dark green cones make this coneflower shine like a jewel, standing out even among bright orange, purple and white echinaceas. Large and full-formed, the 3-4" blooms make excellent cuttings. Compact clumps to 2 feet tall stay upright without staking. Grow as a foil to sizzling-colored perennials or to cool down your sun garden, mixed with white and blue bloomers.


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How did Hollywood become Hollywood? If you ask the operators of The Pirate Bay and their apologists, they'll say Hollywood was built by a band of pirates, fleeing stringent East Coast patent protections to a free and open land to create at will. This theory conveniently parallels their own existence, as they seek to justify profiting from digital theft. Spoiler alert: their story is fiction. Copyhype's Terry Hart chronicles the origins of the heart of showbiz in a recent piece, debunking the theory that filmmakers' migration west was to flee enforcement of intellectual property laws.
As Hart points out, the patents at issue were held by the Motion Picture Patents Company, which, through restrictive tie-in agreements and licensing practices, severely impeded independent filmmakers from entering the market. But the status quo was challenged, and shortly afterwards, the Supreme Court determined that MPPC's licensing practices give it "a potential power for evil over" movie producers which "would be gravely injurious to th[e] public interest." This 1917 ruling severely undermined MPPC's unfair business practices.
So why did so many filmmaker make the trek cross-country to the Golden State? Geography is one good reason, says Hart.
The landscape of Southern California provides a multitude of options for filmmakers when choosing their films' setting. Weather is another good reason, he adds. The transition from harsh East Coast winters to 70 degrees and sunny was certainly a welcome one for the film community. Not to mention land was cheaper and labor more available. It seems landscape, climate, and business were all an improvement for creators looking to relocate.
Thus, while the "Hollywood was created by pirates" schtick may be cute, it is a false narrative pressed primarily by copyright opponents as a way to validate online content theft.
Categories: Content Protection, Copyright
Tags: Hollywood, Copyhype, MPPC, Supreme Court
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Sports Photos
Photos from the career of Mr. Cub - Dallas native Ernie Banks
Photo: CHICAGO TRIBUNE PHOTOGRAPH/CHICAGO TRIBUNE
Ernie Banks, Mr. Cub, signs autographs in 1964
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I'm writing this post using the Swype beta on my new Google Nexus 7 tablet. At this point, I am completely spoiled. I'll never be able to go back to using a normal keyboard on a tablet device. I got used to Swype on my Droid 2, but this beta is even better than the… Read more »
Posts Tagged: swype
I want… iOS vs. Android revisited
I wrote this post about my wishlist for iOS and Android over a year ago, and it's due for a refresh. iOS Swype – it's still missing. The keyboard on iOS is still much the same. The split keyboard showed up in iOS 5, but really nothing for my iPod touch. There is a hidden auto-complete suggestion… Read more »
I want… iOS vs. Android
UPDATE – This post is over a year old now. An updated version of this post can be found here. I've been meaning to do this for a while now. I own both an iPod Touch and a Droid 2. I primarily use the Droid 2, but I still occasionally fall back to the Touch… Read more »


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Experts: State's turnpike corruption 'the worst such case'
HARRISBURG — The Pennsylvania Turnpike scandal is the worst of its kind in the nation in recent history, experts say.
"There's been nothing as systemic, as enduring and widespread," Peter Samuel, publisher of Tollroadsnews.com in Frederick, Md., said of allegations in a state grand jury report last month.
Attorney General Kathleen Kane has said the investigation continues; the grand jury had concluded that eight people, including a former Senate Democratic leader and former top turnpike officials, used the agency as a "cash cow" to raise campaign money for lawmakers and gubernatorial candidates. Campaign donations and gifts paved the way for rigged turnpike contracts in a pay-to-play scheme, the grand jury said.
Such schemes have surfaced in other states, though usually not with toll road agencies, said Craig Holman, lobbyist for Public Citizen, a consumer advocacy group in Washington.
"Fifteen states have pay-to-play laws," Holman said, the strongest of which are in Illinois, New Jersey and Connecticut, which dealt with scandals.
These laws typically ban campaign donations from contractors at the start of negotiations or before, Holman said. Strict laws cover the company and senior executives.
"This situation in Pennsylvania makes Pennsylvania ripe for a pay-to-play law," Holman said.
Gov. Tom Corbett would support such a law, given he has an executive order that does the same for agencies under his control, said his spokesman, Kevin Harley. The turnpike is one of several independent agencies. The next governor isn't bound by Corbett's executive orders.
Although the turnpike scandal is not an isolated incident at toll road agencies, others have been narrower in scope.
In Maine, the turnpike director last year went to prison for stealing hundreds of thousands of dollars by using gift cards and credit cards for travel to resorts and plush accommodations. Paul Violette pleaded guilty to felony theft.
A lawsuit alleged that Violette used the cards for personal travel, hotel and meal expenses on trips in Maine, Florida, Bermuda, Canada, France, Puerto Rico, Spain and Italy, The Associated Press reported.
Pennsylvania's corruption appears to be "the worst such case, of a large scale, over a long period of time," said Robert Poole, transportation fellow at the Reason Foundation, a free-market think tank in Los Angeles. The grand jury report covered activities over a decade.
Turnpike spokesman Carl DeFebo said he had no comment. CEO Mark Compton has said he will try to change the culture of the agency.
Illinois Gov. Rod Blagojevich, sentenced to 14 years in federal prison, tried to sell a Senate seat and to use the Illinois Tollway to extort money from contractors for campaign money, prosecutors said. Tollway officials were not implicated in the case against Blagojevich. He was considering the choice between a $1.8 billion and $5 billion road expansion program and, in meetings wired by federal agents, Blagojevich made it clear the $5 billion project would not go through if he didn't get sufficient campaign money, Tollroadsnews.com reported.
A 50-page report in 2012 by the Office of Inspector General of the Department of Transportation on the Metropolitan Washington Airports Authority, which operates Dulles Toll Road, said the authority's "weak policies and procedures led to questionable procurements and lacked overall accountability."
Employees accepted gifts from contractors such as Super Bowl tickets, travel and accommodations, the report said. It cited instances in which non-public information went to potential contractors, giving them an edge. No one was charged.
This month, the Philadelphia Inquirer reported a federal investigation is under way of the Delaware River Port Authority, which operates four toll bridges and a commuter rail line, for its development spending. No one is accused of wrongdoing.
Brad Bumsted is Trib Total Media's state Capitol reporter. Reach him at 717-787-1405 or firstname.lastname@example.com.
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Microsoft's official Group Policy blog
It's interesting what you can discover when you right-click on something. For example, in the Group Policy Management Console (the GPMC) you can right-click on a domain and select "Search", and a this amazing tool presents itself. This handy search tool is available with Windows Server 2003+ (if you have the GPMC, you have Search). Read more about it here.
You can search for GPO's that have been linked or not, that contain settings under User or Computer Configuration including Deployed Printer Connections, Group Policy Folder Options, Group Policy Network Shares, Registry, Internet Protocol Security Policies, Scripts, and a lot more. Check it out :
You can add more rules to your search criteria by just clicking "Add" to the current criteria you've created, then re-selecting from the drop down menus. These drop-down menus are intelligent; they auto-populate with relevant values. For example, if you search for Security Group in a GPO, the Security Group search dialog will pop up.
Watch the video below to see me search for GPO's that have registry configurations and that are linked to my domain. Watch for the Security dialog pop up as well (though I didn't fill it out, just wanted to demonstrate it).
First, I open the Search dialog. Then, I add my 2 search criteria and get a list of 2 qualifying GPOs. I then click 'edit' to show that you can directly view the GPO from this search window. Finally, I click 'save results' and end up with a comma separated value file that lists out the relevant GPO's. Enjoy!
LiliaG, Group PolicyPM
I am running Windows Vista Home Premium 32-bit. My goal is to have gpedit.msc open and allow me to use it's functions. The main function I want to use is add to the Save In sidebar/favorites and have the save in window open to a differt default location. I have been told this is not available in the Home Premium version. I know you will say "no way", but, on my previous install of Home Premium I was able to access gpedit.msc and use it. I did that install myself, using the same disc I used this time around. I am not mistaken. I did a clean install and now it appears it's not even on my system. Several things seem different this time around. I will focus on this one issue. I tried to do this on my own. I downloaded and installed Windows6.0-KB943729-x86.msu, GPMCSampleScripts.msi and VistaADMX.msi. I rebooted. I still cannot access gpedit.msc. The blank console opens with the message "MMC could not create the snap-in". Please, help me. What am I doing wrong? What else do I need to download and install? The things I did install, if they are incorrect, do they need to be uninstalled? Thank you.


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You Are Here: Home » Find People » NINDS Staff »
Dr. Deborah Hirtz is a Program Director for Clinical Trials and Studies. She received her undergraduate degree at the University of Chicago and medical degree at Hahnemann Medical College. She is board-certified in Pediatrics and Neurology, and trained in pediatrics and neurology at the Children's Hospital Medical Center and George Washington University in Washington, DC. Since that time, she has been at NINDS, and has also been a clinical consultant in Child Neurology for the Montgomery County Health Department and the National Children's Center. Her interests include clinical trials, seizure disorders in children, autism and other developmental disorders, cerebral palsy, other neurological disorders of infants and children, and optical imaging.
Active Funding Initiatives for Dr. Hirtz
Last Modified May 31, 2013


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|GROUP EVENT for: Silicon Valley Super Club -01/29/13 - Monthly Dance Meet/greet
|Monthly Dance Meet/greet [All Events List]
|Silicon Valley Super Club Monthly Dance Meet/Greet
|Campbell, California
|SLS Liaison:
Silicon Valley Super Club
URL: View Group
|Come one come all to our monthly meet/greet Dance party.
7-8 Meet n Greet bring a little snack to share
8-10 Dance
This is a public venue, but we usually have it to ourselves until 10pm. All are welcome, please be respectful.
Please register online and host will contact you with location details. Looking forward to seeing you there.
Cost $5.00 clean up fee.
b n t teeze4fun
|23 members are attending this event.
|Click Campbell Swingers to find local swingers
|Events listed above are provided for informational purposes only. SwingLifestyle.com does not control the venue or the events themselves, and cannot guarantee that the events will occur on the dates indicated above. Be sure to check with the specific venues for the latest updated information.


text: National Night Out: 'It's a vital step in crime prevention and safety' Share this story email Share this story «Previous 22 of 24 Photos Next » Read the story « » National Night Out Michael Dinsmore and Eric Vickoren, right, fight in Medieval style armor during the National Night Out event in Ferry Road Park Tuesday Aug. 7, 2012 in North Bend, Ore. The 29th annual National Night Out helps organize communities to fight against drug use and crime. The fighters are members of the local chapter of the Society for Creative Anachronism, a 40-year-old organization of people interested in Medieval history. (AP Photo/The World, Benjamin Brayfield)


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Originally posted by Ilja Preuss: Because the call to doIt in the TopClass constructor is polymorphic, that is, it will call the actual method on the object...
Originally posted by Sherry Jacob: I mean if I am making a derived class object, why is it calling the function doIt(10) in DerivedClass ? Cud u elaborate ?
Originally posted by Arun Kumarr: When the JVM sees the doIt() method in superclass, How does it call the Derived classes' doIt() method?? bcoz' at that point there is no Derived Class constructed at all.
Originally posted by Arun Kumarr: Since the JVM decides which method to call on the fly, Why is that it is confused when the methods are static?


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Antimicrobial stewardship has been promoted as a key strategy for coping with the problems of antimicrobial resistance and Clostridium difficile. Despite the current call for stewardship in community hospitals, including smaller community hospitals, practical examples of stewardship programs are scarce in the reported literature. The purpose of the current report is to describe the implementation of an antimicrobial stewardship program on the medical-surgical service of a 100-bed community hospital employing a core strategy of post-prescriptive audit with intervention and feedback.
For one hour twice weekly, an infectious diseases physician and a clinical pharmacist audited medical records of inpatients receiving systemic antimicrobial therapy and made non-binding, written recommendations that were subsequently scored for implementation. Defined daily doses (DDDs; World Health Organization Center for Drug Statistics Methodology) and acquisition costs per admission and per patient-day were calculated monthly for all administered antimicrobial agents.
The antimicrobial stewardship team (AST) made one or more recommendations for 313 of 367 audits during a 16-month intervention period (September 2009 – December 2010). Physicians implemented recommendation(s) from each of 234 (75%) audits, including from 85 of 115 for which discontinuation of all antimicrobial therapy was recommended. In comparison to an 8-month baseline period (January 2009 – August 2009), there was a 22% decrease in defined daily doses per 100 admissions (P = .006) and a 16% reduction per 1000 patient-days (P = .013). There was a 32% reduction in antimicrobial acquisition cost per admission (P = .013) and a 25% acquisition cost reduction per patient-day (P = .022).
An effective antimicrobial stewardship program was implemented with limited resources on the medical-surgical service of a 100-bed community hospital.
Keywords:Antimicrobial stewardship; ASP; Small community hospital
Hospitals with less than 200 beds accounted for 72% of American Hospital Association-defined community hospitals in 2008 and 63% of the acute care facilities reporting to the National Healthcare Safety Network (NHSN) in 2010 [1,2]. Recent reports have demonstrated that large and small hospitals alike comparably share the problem of antimicrobial resistance. An analysis of data from the National Nosocomial Infection Surveillance (NNIS) System demonstrated parallel increases in antimicrobial resistance in Staphylococcus aureus blood stream infections, Escherichia coli urinary tract infections and Pseudomonas aeruginosa pneumonias within large and small acute-care facilities between the periods of 1990–1994 and 2000–2004 [3]. In addition, intensive care units of small and large hospitals reporting to NHSN were shown to have comparable proportions of device-associated infections with multidrug-resistant Klebsiella pneumoniae and E. coli[4]. Similarly, the proportion of Acinetobacter baumannii that was multidrug-resistant was comparable or greater in smaller facilities compared to larger, tertiary facilities. Furthermore, smaller bed size was independently associated with a higher rate of incident Clostridium difficile infection (CDI) cases reported among 210 Ohio acute care hospitals during 2006 [5].
Antimicrobial stewardship has been promoted for all hospitals to help cope with the challenges of CDI and emerging resistance to antibiotics [6-8]. In 2007, the Infectious Diseases Society of America (IDSA) and the Society for Healthcare Epidemiology of America (SHEA) published revised guidelines for developing institutional programs to enhance antimicrobial stewardship [9]. Several recent surveys have suggested antimicrobial stewardship programs (ASPs) may be more prevalent than appreciated from a review of the medical literature [10,11]. Nevertheless, a 2011 report of a survey of infectious diseases (ID) specialists of the IDSA Emerging Infections Network concludes that "small community hospitals still represent the 'frontier' for new stewardship programs" and that they are the hospitals "least likely to have ASPs, the least likely to provide compensation to physicians, and the least likely to believe that any outcomes data might convince administrators to support ASPs" [12]. Even so, smaller hospitals may have higher rates of antimicrobial use than those of large academic medical centers [13]. It has been nearly a decade since the only report of an ASP from a community hospital in the United States with less than 200 beds [14]. We report the implementation of a contemporary ASP on the medical-surgical service of a 100-bed community hospital.
Program setting
An ASP was implemented on the medical-surgical service of a full-service 100-bed community hospital located in an ethnically diverse community in metropolitan Dallas, TX. The 43-bed medical-surgical service consisted of a 24-bed medical-surgical floor unit, 11-bed progressive care unit, and 8-bed medical-surgical intensive care unit. There were no inpatient transplant services, specialized oncology, pediatric, psychiatric, or rehabilitation units. Medical subspecialties were broadly represented and included infectious diseases (ID); surgical specialties included cardiothoracic surgery, colorectal surgery, general surgery, neurosurgery and orthopedic surgery. An electronic medical record was available but without computerized physician order entry or electronic progress notes.
Throughout the reported period, a nurse staffed an infection prevention and control program that included surveillance and prevention activities for multidrug-resistant organisms, CDI, and device-associated infections. Since 2006 and throughout the reported period, an ID physician served as the medical director of infection control and employee health. Active admission surveillance testing for methicillin-resistant Staphylococcus aureus was performed on high-risk patients for isolation and cohorting purposes. An off-site laboratory performed microbiology services including preparation of an annual facility antibiogram and polymerase chain reaction testing for CDI. (Laboratory testing for CDI was performed on-site using an enzyme-linked immunoassay for C. difficile toxin prior to November 2009).
The pharmacy was staffed by 6.4 full-time-equivalent pharmacists, including a pharmacy director and clinical pharmacy supervisor. The pharmacists did not receive specialized training in infectious diseases.
During the baseline period (January 2009 – August 2009), the ID physician medical director of infection control, the clinical pharmacy supervisor and the pharmacy director together formed an Antimicrobial Stewardship Team (AST) and drafted an antimicrobial stewardship policy and program description for approval by the Pharmacy and Therapeutics Committee and Medical Executive Committee. AST members educated the medical staff about the program through presentations at medical staff committee meetings and through a continuing medical education conference. For approximately one hour twice weekly during the intervention period (September 2009 – December 2010), the ID physician and one or the other of the AST pharmacists audited medical records of inpatients on the medical-surgical service that were receiving more than two days of systemic antimicrobial therapy. On occasion, the AST audited other patient records with shorter durations of therapy. The AST members audited records for prescribed antimicrobial agent(s), clinical indication(s), planned treatment duration(s), drug allergies, renal function, pertinent laboratory and radiographic data. Non-binding written recommendations were made and placed in the record using a communication form that did not become part of the permanent medical record. There were no formulary restrictions or preauthorization requirements.
Additional interventions implemented prior to the baseline period included automatic vancomycin dose-optimization and a pneumonia order set. Order sets for treating patients with severe sepsis or, suspected severe sepsis, and a parenteral to oral conversion protocol were implemented during the intervention period. A timeline with ASP milestones and interventions is displayed in Figure 1.
Figure 1. Antimicrobial stewardship program implementation timeline. The timeline depicts antimicrobial stewardship program milestones and interventions. A pneumonia order set and vancomycin dose-optimization protocol were implemented prior to the baseline period. Severe sepsis order sets and a parenteral to oral conversion protocol were implemented during the intervention period. The severe sepsis order sets included choices for initial antibiotic regimen by suspected source of infection and a schedule for continued therapy without automatic stop orders or requirements for physician justification. Individual agents included in the order sets were ampicillin, ampicillin-sulbactam, azithromycin, aztreonam, ceftriaxone, levofloxacin, linezolid, meropenem, piperacillin-tazobactam, rifampin and vancomycin. Antimicrobial agents in the parenteral to oral conversion protocol were fluconazole, levofloxacin, linezolid, metronidazole and voriconazole at the same dose and frequency.
Data collection
The AST categorized recommendations as follows: to discontinue all agent(s), to de-escalate antimicrobial therapy (to discontinue one or more agents and/or substitute an alternate agent(s) with decreased spectrum of activity), to limit duration, to broaden coverage (to add one or more agents and/or substitute alternate agents(s) with increased spectrum of activity), to optimize dose (e.g., for indication, renal function, and/or body weight), to convert route of administration from parenteral to oral and to consult ID. Pharmacist team members followed up recommendations and scored implementation. Data from record review and recommendations were tabulated monthly.
Admissions, patient-days (excluding outpatient-days), Medicare Case Mix Index, and characteristics of patients discharged from the medical-surgical service were obtained from hospital administrative databases. Facility-wide acquisition and/or return costs and quantities for all systemic antimicrobial agents (antibacterial, antifungal and antiviral) were recorded monthly from pharmacy records for the baseline and intervention periods. In addition, administered quantities of antimicrobials were recorded monthly for each patient care location of the medical-surgical service and defined daily doses (DDDs; World Health Organization Center for Drug Statistics Methodology) were calculated. Antimicrobial acquisition costs were estimated by multiplying administered antimicrobial unit quantities by the 2009–2010 facility average acquisition price per unit. Incident healthcare-facility-onset CDI cases were scored and incidence rates calculated per 10,000 patient-days according to the NHSN multidrug-resistant organism and CDI module protocol laboratory-identified event methodology [15].
Statistical analysis
Patient characteristics, antimicrobial use and cost, and CDI rates were compared during baseline and intervention periods. The Mann–Whitney U test was used for continuous variable distributions, and the χ2 test was used for categorical variables. All reported P values were two-tailed with P less than .05 as the level of significance. Statistical calculations were performed using GraphPad Prism, version 5.04.
Patient characteristics
There were 1,422 admissions and 5,572 patient-days on the medical-surgical service during the 8-month baseline period and 3,076 admissions and 11,109 patient-days during the 16-month intervention period. Patient characteristics of the medical-surgical service are summarized in Table 1. Primary diagnoses were similar between the two periods except for diseases of the circulatory system (P = .027). The mean monthly, facility-wide Medicare Case Mix Index increased from 1.4 to 1.6, or by 14% (P = .005).
Table 1. Patient characteristics during baseline and intervention periods of an antimicrobial stewardship program
There were 367 audits of 333 unique inpatient records during the stewardship period (Table 2). At the time of audit, 349 (95%) patients had been prescribed antimicrobial therapy for three or more consecutive days, 168 (46%) were receiving more than one agent, 206 (56%) were receiving fluoroquinolones (levofloxacin) and 13 (4%) were receiving two agents with anaerobic activity. Suspected or confirmed pulmonary infection was a rationale for antimicrobial therapy in 173 (47%) audits and the most common indication for prescribed antimicrobial therapy.
Table 2. Characteristics of antimicrobial prescription regimens from 367 audits of 333 unique patient medical records
Characteristics of AST recommendations are summarized in Table 3. The AST advised no change to the prescribed antimicrobial regimen for 54 audits and made one or more recommendation(s) to change the prescribed antimicrobial regimen (or consult ID) for 313 audits during the stewardship period. Physicians implemented recommendation(s) from each of 234 (75%) audits, including from 85 of 115 for which discontinuation of all antimicrobial therapy was recommended.
Table 3. Characteristics of 313 AST audits with one or more recommendations
Antimicrobial use and cost, and CDI
There was a 22% reduction in mean monthly use of all antimicrobial agents per 100 admissions (P = .006) and a 32% reduction in cost per admission (P = .013) in comparison to the baseline period (Table 4). Antimicrobial use and cost were also calculated per patient-day. There was a 16% reduction in mean monthly antimicrobial use per 1000 patient-days (P = .013) and a 25% reduction in cost per patient-day (P = .022). There were statistically significant reductions from baseline in the use of antipseudomonal carbapenems (imipenem and meropenem), clindamycin, levofloxacin, linezolid, trimethroprim-sulfamethoxazole, antibacterials and antifungals using either metric denominator; there was a statistically significant increase from baseline in the use of cefazolin.
Table 4. Antimicrobial use and cost during baseline and intervention periods of an antimicrobial stewardship program
The mean monthly, incident healthcare-facility-onset CDI incidence rate for the medical-surgical service was 3.7 during the baseline period and 9.2 during the intervention period (P = .232).
In summary, we report the implementation of an ASP at a 100-bed community hospital employing a core strategy of post-prescriptive medical record audits and nonbinding AST recommendations with significant reductions in antimicrobial use and cost.
Respondents to a 2009 survey of the IDSA Emerging Infections Network on programmatic strategies and barriers for ASP implementation, reported that 61% of their hospitals had an ASP and that 12% were planning to initiate one [12]. However, respondents from hospitals with less than 200 beds reported that only 44% of their hospitals had an existing ASP; even so, the survey was thought to "likely overestimate the dissemination of ASPs". Lack of funding and/or personnel were considered to be primary barriers to ASP implementation.
Additional challenges in the implementation of our program included data management and the creation of data management tools, program documents, procedures, and reports as well as educational materials for the medical staff.
Although other reports have been published about ASPs implemented in community hospitals [16,17], only one has previously described an ASP at a facility in the United States with less than 200 beds. In 2003, LaRocco described an antibiotic support team developed at a 120-bed facility in Louisiana [14]. Concurrent chart review was performed three days per week focusing on multiple, prolonged and high-cost antibiotic therapies. There was a 19% savings on antibiotic costs per patient-day over a 12-month intervention period. We employed a similar core strategy but with a 2-person ID physician/clinical pharmacist team that audited medical records two days per week. We limited our audits to patients on the medical-surgical service, as others have reported [18], and demonstrated a 25% cost reduction per patient-day (P = .022). LaRocco did not report use metrics; there may be other unknown differences in the setting, patient characteristics, interventions, and data analysis limiting any further comparisons between these two programs.
The generation of recommended antimicrobial use metrics was among our greatest challenges. We selected DDD as recommended by the IDSA/SHEA stewardship guidelines [9]. Days of therapy were not available from pharmacy records. These same stewardship guidelines are silent on the recommendation for a metric denominator(s); we calculated both DDD per admission and per patient day, as recommended by others [19-21].
There were few differences in patient characteristics between the baseline and intervention periods. The facility-wide Medicare Case Mix Index increased significantly during the intervention period; however it is unclear how this may be related to antimicrobial use on the medical-surgical service.
Severe sepsis order sets and a parenteral to oral conversion protocol were implemented during the intervention period. The order sets did not limit duration of antimicrobial therapy and the parenteral to oral conversion protocol included only five antimicrobial agents eligible for substitution at the same dose and frequency. Nevertheless, we cannot exclude the possibility that these additional interventions may have had an impact on antimicrobial use and cost.
Similar to other recent reports from the United States, we observed more than one antimicrobial agent was prescribed for 46% of audited records. In a retrospective study of adult, nonpsychiatric inpatients prescribed two or more consecutive days of antibiotic therapy at a tertiary care hospital in New York, two or more antibiotic agents were employed for 63% percent of 10,154 hospitalizations [22]. In an observational study of adult inpatients prescribed fluoroquinolones at a tertiary care hospital in Ohio, 56% of 227 regimens combined fluoroquinolones with antibiotic agents from other classes [23].
We observed a pulmonary source of infection was an indication for antimicrobial therapy in 47% of audited records. In addition, a fluoroquinolone, levofloxacin, was prescribed in 56% of audited records and accounted for approximately 30% of overall antibiotic consumption on the medical-surgical service during both the baseline and intervention periods. We speculate that these findings may in part be related to antibiotic choices in a pneumonia order set designed to align with the Centers for Medicaid and Medicare Services National Inpatient Quality Measure PN-6, "Initial Antibiotic Selection for Community-Acquired Pneumonia (CAP) in Immunocompetent Patients" [24].
Discontinuation of all antimicrobial therapy accounted for 36% (85/234) of audited records with implemented recommendations. The observed reductions in the use of levofloxacin, and of antimicrobials overall, would likely not have been realized if we had chosen a core strategy of antibiotic restriction focused on one or more high cost agent(s). Although inexpensive compared to other antimicrobials and available for oral administration, fluoroquinolones have been associated with both methicillin-resistant S. aureus and CDI in hospitals [25,26]. Receipt of fluoroquinolones and all antibiotics have also been shown to be independent risk factors for carbapenem-resistant K. pneumoniae acquisition among hospitalized adults [27].
Measurement of changes in antimicrobial resistance patterns associated with antimicrobial stewardship has been recommended as a potential outcome measure for ASPs [9]. In the current report, small numbers of unique clinical isolates precluded a meaningful assessment of the program's impact on antibiotic resistance. Likewise, a switch from enzyme immunoassay detection of toxins to a polymerase chain reaction assay in month 3 (November 2009) of the 16-month ASP intervention period likely confounded comparison of healthcare-facility-onset CDI rates. (A recent report demonstrated significant increases and an approximate doubling of the prevalence of positive laboratory tests for CDI and the CDI rate after a similar switch in detection methods [28]). Also, factors other than antibiotic use may affect CDI, and we were unable to draw any conclusions about the statistically unchanged CDI rates between the periods [29].
In conclusion, an effective ASP was implemented at a 100-bed community hospital. Importantly, there were significant reductions in overall antimicrobial use. More focus is needed on antimicrobial stewardship strategies, measures and resources in this healthcare setting.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
DS, PP, AN, and FC shared in program conception and design. DS served as the physician champion for the medical staff. PP developed the data management tool and performed data analysis. DS, AN, and FC performed medical record audits. DS and PP drafted the initial manuscript. All authors have read and approved the final manuscript.
Previous presentations
Presented in part: 21st Annual Scientific Meeting of the Society for Healthcare Epidemiology of America, Dallas, TX, 1–4 April 2011 [Abstract 77].
We thank Dr. Bob Bolton for assistance with medical record audits and Dr. Linda Hynan for her helpful statistical review of the manuscript.
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