text:
[245] Analysis of FOXP3 mRNA Expression in Subtypes of Breast Carcinoma and Breast Cancer Cell Lines
Fernando Ortiz-Martinez, Ariadna Perez-Balaguer, J Miguel Sempere-Ortells, Montserrat Rodrigo, Jose Ponce, Pascual Martinez-Peinado, Enrique Lerma, Jose Sanchez-Paya, F Ignacio Aranda, Gloria Peiro. University General Hospital, Alicante, Spain; University of Alicante, Alicante, Spain; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Background: The X-linked gene FOXP3 (Xp11.23) plays a key role in the immune suppressive function of regulatory T-cells (Tregs). More recently, it has been identified as a tumor suppressor gene that regulates tumor development. Here, we analyzed the expression of FOXP3 mRNA in breast cancer (BC) cell lines representing different phenotypes together with a series of BC patients.
Design: BC cell lines consisted of MCF-7, T-47D, BT-474, SK-BR-3, MDA-MB-231, MDA-MB-468 and a normal epithelial breast cell line, 184A1. Quantitative RT-PCR was performed using TaqMan® Assays. Mammary tissue and 184A1 were used as calibrators for tumor samples and BC cells, respectively; PUM1 and ACTB were the reference genes. Expression was determined using the ΔΔCT method and was expressed as fold change (FC). 189 BC tumors were classified immunohistochemically into Luminal (32%), HER2+ (36%) or TN/BL (32%).
Results: FOXP3 mRNA expression was higher in Luminal subtype cell lines (MCF-7 FC=4.87; T-47D FC=12.11) and in Luminal/HER2+ cells (BT-474 FC=4.77) compared with HER2+ cells (SK-BR-3 FC=2.83) and TN/BL cells (MDA-MB-231 FC=0.11; MDA-MB-468 FC=0.31). Median patient's age was 57 years (range 26-89) and the median follow-up was 85 months (range 6-259). Tumors showed vascular invasion in 51% (85/167), necrosis in 45% (74/164) and positive lymph node-status in 34% (62/181). Low FOXP3 mRNA expression (FC<0.5) (35%, 67/189) predominated in Luminal (42%, 27/65) and TN/BL subtypes (39%, 25/65; p=0.004), with lower histological grades (1+2 vs 3) (51%, 34/67; p=0.013). Patients with decreased FOXP3 tumor levels had longer overall survival (85% vs 69%; p=0.012). Phenotype stratification also showed a trend to better prognosis in those with Luminal (96% vs 79%), HER2+ (77% vs 63%) and TN/BL (76% vs 68%) tumors (p=0.11; Kaplan-Meier, log-rank test).
Conclusions: Low level of FOXP3 mRNA correlated with good prognostic factors. Moreover, we identified a subgroup of patients with better prognosis in all immunophenotypes of BC. The results of FOXP3 mRNA expression in BC cell lines and tissues were comparable only in TN/BL phenotype, showing low levels of expression.
Supported by Grants FIS 10/00082, AP-172/10, FCVI-HGUA (2010/PC-04 and 2011/PC-03).
Category: Breast
Tuesday, March 5, 2013 1:00 PM
Poster Session IV # 33, Tuesday Afternoon


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November 29, 2015
MILWAUKEE (AP) - Mike Pelfrey bailed the New York Mets out of a season-worst losing streak, overcoming a career-high 12 strikeouts by young Milwaukee Brewers ace Yovani Gallardo in a 1-0 victory Wednesday.
Pelfrey (6-3) gave up six hits and two walks in 7 2-3 scoreless innings and Ryan Church came through with an RBI single in the sixth as the Mets stopped a five-game losing streak and avoided a series sweep by the Brewers.
Gallardo (8-5) gave up five hits in seven innings. The Brewers completed a 5-4 homestand and will travel to Chicago for a four-game series against the Cubs beginning Thursday.
Copyright 2015 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
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subset: commoncrawl


text:
Printing Postcards
These days, you can print just about anything - even postcards. Instead of buying postcards from a paper or card company, you can design your own postcards and print them out on high-quality paper. Printing postcards is easy, and 123inkjets has a few tips to help you get started.
Use a digital camera
If you love to send postcards to friends and family while you are away on vacation, make sure to bring along your digital camera. You can take high-quality scenic or funny photos of your vacation spot and use them as your postcard. Turning digital photos into postcards is easy, and it allows you the unique ability to personalize your postcard. With a little bit of creative editing, you can add text, borders, and other special affects to your photo and presto - instant postcard!
Use a high-quality printer
The quality of your postcard will depend on the quality of your printer. There are many different inkjet printers to choose from. Do a little research and read as many customer reviews as you can find. This will allow you to make an informed decision about the kind of inkjet printer that will best fit your needs. Some inkjet printers are designed specifically for people who print photographs. Since you will be using digital photos to design your postcards, you will need a printer that is reliable and capable of printing high-quality digital photos.
Consider the ink
Most people don't think about the ink that they use. It is usually the last thing on their minds, except when they need to order more. You need to purchase ink cartridges with fast-drying capabilities. Since you will be printing photos on a regular basis, you will need a decent amount of ink. This can be costly. You can save money simply by purchasing high-quality refurbished ink cartridges. Refurbished ink cartridges are recycled ink cartridges. They are better for the environment and cost much less than new ink cartridges. You can purchase refurbished cartridges in bulk orders as well.
Use postcard stock paper
A postcard needs to be thick and durable because you are going to be sending it through the mail. Do not cheap out on the paper quality because it will ruin your postcard. You can purchase postcard paper at any store that sells paper products. If you can purchase coated postcard paper then do so. It may be more expensive but it offers the kind of paper quality you need in order to bring your postcards to life.
Creating your own postcards is a unique and fun way to keep in touch with family and friends when you are away on vacation. If you have a digital camera, the right printer, the right ink, and the right kind of paper, you can easily design a high-quality postcard. The next time you plan on going on vacation, make sure that you have everything you need in order to create the perfect postcard. Your family and friends will be amazed!
Find out about the latest 123inkjets discounts, coupons, and deals.


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text: Originally posted by Jamie Robertson: I have seen this problem extensively with certain combinations of the jdbc dbc bridge and MSAccess. Stop pulling your hair out, there are 2 workarounds to force this last record to insert: 1) Close the connection each time afterwards. 2) Do a dummy select each time afterwards. That seems to be the better one. That means: after your last insert (not after each record) do this "trick".(after "insert into emp..." execute a query "select something from emp...) Not sure if the select has to be from the same table as the insert, but you can try it both ways Jamie


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Candidates for Governor in Colorado, Michigan, Texas and elsewhere are running Web ad campaigns to push their messages.
House and Senate campaigns aren't the only ones heating up. Gubernatorial races are getting down to the wire, too, and some are using the Web as a strategic component of their campaigns. Video ads, search and voter-generated ad contests are among the more innovative means of sparking interest and reaching voters who aren't glued to the TV. But for some, as November 7 nears, the Web becomes less and less important.
"Colorado is just a big state," said Evan Dreyer, spokesman for the Bill Ritter for Governor campaign. "To try to get everyone covered we decided to do some online advertising rather than straight print advertising, to start to generate recognition." The campaign has run ads since early this summer on sites including The Coloradoan's Web presence, that of The Durango Herald, RockyMountainNews.com and DenverPost.com, according to Dreyer.
Running as an independent alongside cult hero Kinky Friedman and a handful of other opponents vying for the big seat in Texas, Carole Keeton Strayhorn is linking expandable, interactive video ads to her OneToughGrandma.com site. Some of the PointRoll banners feature additional video upon rollover; others include a poll, volunteer sign up or link to donate within the expanded unit. The campaign is running ads on Austin's Statesman.com and its related network sites, as well as MyWestTexas.com, Dallas's NBC5i.com, Houston Chronicle's Chron.com, Click2Houston.com, MySanAntonio.com and others.
Strayhorn's Republican opponent and incumbent Governor Rick Perry is running Flash-based video ads repurposed from TV spots on Statesman.com, according to Jeff Friedman, the site's online sales manager. Both Strayhorn's and Perry's efforts started around September, he added.
Eric Frenchman, video ad proponent and CTO at political marketing agency Connell Donatelli said the campaign for Michigan Republican candidate Dick DeVos began testing its online ads in the beginning of the year. The campaign is running PointRoll video banners on ClickOnDetroit.com, CitySearch.com, MLive.com, The Detroit News and Detroit Free Press.
Though it can take some coaxing, getting a candidate to agree to run an online video ad "comes down to how comfortable they are with online," said Frenchman, adding, "It just sounds scary when it comes from going from not doing anything online to streaming your TV ad online." According to Connell Donatelli, the DeVos video banners, which allow users to subscribe to campaign e-mails and donate, garnered more than 1,200 hours of interaction as of September 27.
The DeVos campaign appears amenable to moving beyond tried and true approaches. Taking a cue from a multitude of commercial campaigns, the candidate's site features a "Create Your Own DeVos for Governor Video Contest," and asks supporters to "Use any content, television ads, press releases, websites, you name it...to create your own DeVos for Governor video." The prize, of course, is a Video iPod, in addition to having the voter-generated ad "featured" by the campaign.
The DeVos effort also involves a "very, very, in-depth" geo-targeted search campaign, buying search keywords like "Michigan Weather," Frenchman told ClickZ News.
Democratic candidate Ritter isn't doing much of anything by way of search advertising, said Dreyer. However, the campaign is taking advantage of social networking favorites MySpace, Facebook and YouTube, as well as keeping in touch with bloggers and sending lots of e-mail newsletters. The campaign makes an effort to post all new video snippets on YouTube, and started building its MySpace and Facebook networks this summer. "One of the people who spearheaded that is Bill Ritter's 20-year-old son," noted Dreyer.
Paid online media buys are on their way out for the Ritter campaign as election day looms. In recent weeks, Ritter's Web ad buy has been whittled down to the news sections of RockyMountainNews.com and DenverPost.com, according to Dreyer, who said a complete phase-out is imminent. From here on, the "strategy in its entirety shifts away from [newspapers] -- via the actual printed edition or site -- and moves largely to broadcast," he said. "Maximizing resources dictates placing all available dollars to broadcast," added Dreyer.
Down south in The Lone Star State, however, Austin-based Statesman.com expects the Strayhorn and Perry campaigns to stick with Web ads till the election, according to Friedman. He chalks it up to Austin's Web savvy residents, noting, "This is one of the most high-tech markets in the country...just about everyone's online."
Other gubernatorial campaigns that have put money towards Web ads this season include failed GOP primary contender for Arizona Governor, Don Goldwater, nephew of the polarizing Barry Goldwater. As tracked by Nielsen/NetRatings AdRelevance, the candidate ran ads on an array of far-flung sites such as OrlandoSentinel.com, Phoenix's azfamily.com, New York Post Online and baltimoresun.com. In addition, Republican candidate for California Lieutenant Governor and current State Senator Tom McClintock has run ads recently on NewsMax, according to AdRelevance.
Kate Kaye was Managing Editor at ClickZ News until October 2012. As a daily reporter and editor for the original news source, she covered beats including digital political campaigns and government regulation of the online ad industry. Kate is the author of Campaign '08: A Turning Point for Digital Media, the only book focused on the paid digital media efforts of the 2008 presidential campaigns. Kate created ClickZ's Politics & Advocacy section, and is the primary contributor to the one-of-a-kind section. She began reporting on the interactive ad industry in 1999 and has spoken at several events and in interviews for television, radio, print, and digital media outlets. You can follow Kate on Twitter at @LowbrowKate.
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text: Sir I'm looking for a diesel car in the Rs.7 lakh to Rs.9 lakh bracket. What is the best option in this segment ? My options are the Maruti Suzuki Sx4 Vdi, the Hyundai i20 Asta, the Volkswagen Vento Trendline and the Hyundai Verna. My trips are more on highways.


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Getting Dr. Charles Garrett to head up the establishment of the Wellspring Center for Professional Futures is a coup for the CREATE Foundation and its Toyota Education Enhancement Advisory Committee.
By luring the New Albany Schools superintendent to take the job, the committee has greatly increased the chances that the center will be successfully developed.
The center, to be built across Interstate 22 (U.S. 78) from the Toyota manufacturing plant in Union County, will be supported by earnings from the $50 million Endowment Fund Toyota agreed to create as part of the manufacturing plant package.
It's no secret that the school project has been floundering. It will take at least $35 million to construct the center, and so far none of that money has been committed from federal, state or private sources. The state legislature is considering a $6 million appropriation as part of a state bond bill.
And school officials in the region have given the idea only tepid – at best – support, and have questioned whether the logistics can be worked out to get students from their schools to the advanced career center for part of the school day.
Now, CREATE and the committee will have what they have needed – a state-wide respected and influential school leader with a reputation for hard work, strong ethics, practical thinking, and a way of getting things done without being divisive.
Moving the Wellspring Center from a pipe dream to a nationally acclaimed show place for career development is a daunting task. We think Chuck Garrett is the right person for the job.


text:
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Stanford QB Andrew Luck LAYS OUT USC?s Shareece Wright
This is an incredible hit by the QB.
Kansas Must Be Destroyed
Sic Semper Jayhawks
is it worse for a quarterback to lead with his head like that or with his shoulder?
Pretty sweet.
Hit him hard enough to knock the ball out again.
Yeah and in case you didnt know how the Utah/ISU game turned out, you can see an update on the ticker below at the 20 second mark. ;)
Originally Posted by isuaggie
Hit him hard enough to knock the ball out again.
Would've been even more sweet if they would've recovered the fumble.
Hilton Coliseum was specifically built to hold in sound with a solid concrete structure, steel doors, and a crowd that sits just a few feet from the court. With a fan base that frequently ranks among the nations largest crowds, players from opposing teams, as well as Iowa State, have said that the floor has shaken due to the loudness of the crowd
Originally Posted by bos
Yeah and in case you didnt know how the Utah/ISU game turned out, you can see an update on the ticker below at the 20 second mark. ;)
When will the pain stop!?!
Awesome hit though.
Originally Posted by 3TrueFans
When will the pain stop!?!
Awesome hit though.
You summed up a typical first date with me. Not sure what that means.
51-20 was the updated score.
Let Prohm's Posse Ride: Georges, Georgios, 3sus, Hallice, Deonte, Abdel, Monte, Matt, and McKaT.
look at stanford. Thats where we will be in 2 years. top 15
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If you think that the fact that something has never happened before means that it is therefore unlikely to happen, you may be comforted by this. Here are the facts:
In the 37 years of divisional play, the New York Mets have won 5 division titles. In 1986, 1988, and 2006, the Mets won their division by blasting away their competition early, building an insurmountable lead, and holding it.
In 1969 and 1973, the Mets won their division by coming from far behind and passing everyone else with an unbelievably strong final month.
In 1970, 1984, 1985, 1987, 1989, 1990, 1999, 2000, and 2001 the Mets were in contention for the division title into at least the final month, and often the last few days of the season, but they never held a first-place lead of more than two games after April in any of these seasons, and of course they did not win the division title in the end.
So. The Mets, in their 45 years of existence, and in the 37 years of divisional play, have never built a significant lead in their division and then lost it. Never. This is very unusual, as fans of many other teams can tell you.
The patterns you see in these pennant-winning or pennant-racing seasons have had an influence on the collective personality of Mets fans. Mets fans know the experience of greatness (which they value because of its rarity). They know the experience of coming from behind, which if you've ever had it, never leaves you. And they know the experience of fighting the good fight, hoping with all their might, and losing with dignity in the end.
Mets fans don't know, and they do not therefore fear the choke, the collapse, the bottom falling out of the universe. They are not like fans of the Phillies, or the Red Sox, or the Cubs, or the Dodgers, or the Blue Jays, or the Giants, or the Angels, or even the Yankees. The Mets have never actually done anything like this. Not in the regular season nor in the postseason.
Okay, this isn't entirely true. Mets fans do remember those September collapses of the puzzling tired-Piazza, crazy-Valentine teams of the late 1990s. In 1997, we could have had the Wild Card, but we fell just short. In 1998, we should have had the Wild Card, but we fell short again. We had had a Wild Card lead but we lost it. In 1999, we won the Wild Card, after losing another Wild Card lead and then having a miracle comeback. But we still should have won the division title. In 2000, we won the pennant. That's great, but it didn't feel as good as it should have because we fell short of winning our division by a single game. And after losing the first three games of the 1999 NLCS, and losing the 2000 World Series to the Yankees in five, we didn't, well, feel so hot. The Wild Card seasons, to be honest, have had their moderately choke-suggestive aspects.
But who knows how to feel about a Wild Card anyway? Wild Cards aren't things you fight for. They're things you settle for. They're consolation prizes. I don't think that the Wild Card seasons have taught Mets fans anything about the psychology of collapse any more than they have taught them about the psychology of triumph.
Let's talk about winning division titles. This is the task at hand. The biggest first place lead the Mets have ever had in their division in a year in which they did not win the division was no more than a game or two, in 1970 or in 1985. That's nothing. We've already had a six-game lead this season.
I'm telling you right now that we will not break whatever our record is for a blown first-place lead. We will win our division this year.
But right now, we're relying a little too much on miracles. Too many of the most impressive players on our team this year thus far are too old or too thinly established to take us all the way to the end. What we need is our core: Reyes, LoDuca, Beltran, Delgado, and Wright, the guys who are established and who aren't too old. They must all stand and be counted. Because we don't yet know if our sparkling rotation of Glavine, Hernandez, Maine, Perez, and Sosa is real or if it is a mirage.
When this season started, I said that the Mets would win between 85 and 105 games this year. They had a very big range of possibility. What is strange is that in mid-June, they still do. And I still think that the range for the Braves and the Phillies is no better than 85 to 95. My gut math tells me that we have a 50% chance of a real pennant race and a 50% chance of a commanding victory.
We must be strong for the Mets. We must not be crybabies. We must not freak out. The 1986 or 1988 team couldn't have lost eleven out of thirteen because of the more balanced and secure ways in which they were constructed. They weren't depending on old guys or second-chance phenoms. Yes, we could lose it this year. This team, unlike the 1986 or 1988 Mets, can lose. But this team can also win big. Unlike the earlier greatest Mets teams, they could build a gigantic lead and they could also choke. But I still say they're not going to.
Why? Because that is what I want to believe.
An earlier version of this post appeared on


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ENB - Region 7 Notices 6/24/2009
Negative Declaration
Oswego County - The City of Oswego Planning Board, as lead agency, has determined that the proposed McDonald's Restaurant - Rebuild will not have a significant adverse environmental impact. The action involves the demolition and replacement of an existing McDonald's Restaurant with a new 4,700 square foot McDonald's Restaurant and associated site work surronding the new building. The project is located at 246 State Route 104 in the City of Oswego, New York.
Contact: Anthony A. Leotta, City of Oswego, City Hall, 13 West Oneida Street, Oswego, NY 13126, Phone: (315) 342-8154.


text:
This red and black flag signifies a storm warning. One flag means Tropical Storm Warning, and two flags together mean Hurricane Warning. (The signals for Gale Warning and Small Craft Advisory are two red pennant (triangle) flags and one red pennant flag, respectively.)
I thought these marine weather flags would make kind of cool throw pillows, so I'm knitting up a couple of envelope-style pillow covers. I'm just making it up as I go along, but I know that if I don't write it down I'll forget how I did it.
What this means:
I just finished writing out my first ever knitting pattern. It is very simple– just a black square inside a red square, using very basic stitches (it's only the front flag part, not the entire pillow cover), but it was HARD to write the pattern, and I'm still not sure it's accurate and user-friendly. So, if you use the pattern, please help me out by leaving a comment about how easy or difficult it was to follow, and what I should do to make it better.
The way it's written assumes you know how to make basic knit and purl stitches, as well as how to join a new color in an intarsia style. (It's not as hard as it sounds! I learned it pretty quickly from YouTube– check out these videos for instructions: Intarsia Knitting Basics and Intro to Intarsia. The second video is by KnitPicks, and it features nautical flags, so yay! Perfect.
Click here to download the PDF pattern.
Sarita Li
Related articles
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- Nautical Flag Knitting: Letter B "Bravo" (thelandlockedsailor.com)
- Nautical Flag Upcycling: It is the East, and Juliet is… the Letter J (thelandlockedsailor.com)


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Some people neglect the benefit that car seat cover sets bring to their own cars. Dust and various particles often adhere to bare Toyota seats and will lead to bad smells together with unclean situations. Once the stock seats remain bare for too much time, it can end up getting very difficult and even costly for you to scrub them. Cheap as well as readily available for anyToyota seat cover everybody needs to possess a pack for easy interior surface care.
Buy matching car seat cover sets for you to enhance your Toyota 's insides effectively. Seat covers come together together with your car's interior design along with a number of unique styles to choose from. Using these products is as easy as pulling them on the car seat and snapping them into place. Setting up the covers is as simple as slipping it over a seat and tying these within position.
Only at Parts Train, we will supply you with the finest in upgraded vehicle parts and accessories like Toyota seat covers. Our web site provides you with accessibility to our entire enormous web based inventory with brands like Coverking, Wet Okole, Rampage, and Seat Armour, to enable you to find the pattern and also the material of our carseat covers. In combination with a competitive selling price promise and speedy shipment solutions, you're sure to get the best bang for your buck here at Parts Train.
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Use our Part Fit Checker to view parts compatible with your vehicle.


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Dead maytag MAV7200AWW washer
Posted 20 April 2005 - 08:27 PM
A month passed by with nothing unusual (the exception being that for two or more months we had to give the lid a good slam to actuate the lid switch and start the wash cycle). Today I was doing a load and gave it the usual lid slam (more of a forceful drop I guess) and nothing happened. After a few tries I figured that I should take a look. I noticed that nothing else now worked. The ATC light wouldn't light up, the timer wouldn't move and if I removed water out of the machine and reset the water level to full it wouldn't refill. I have continuity in the lid switch and I figured if everything is dead then the timer may be the culprit. I carefully removed the timer and opened the housing to expose it's player piano-like guts. I noticed that cam 4 (ATC disable) had severe arc pitting and carbonization. I'm guessing that this is the source of my woes.
Is it possible that I may be overlooking anything else? Could the lid slamming (it did get progressively worse and required a harder slam as time passed) take out the timer?
Posted 21 April 2005 - 03:53 AM
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Posted 21 April 2005 - 11:59 PM
Then take the 2 screws out of the console,
open it up, let it rest gently on the lid of the washer.
inside in the center you will notice a plastic assembly by a fuse on some models without a fuse on others,
but the plastic actuator is common to most Maytags.
in this actuator is a 1/4 inch head screw,
looking from the top, give it a turn to your left.
if you were 2 inches tall and standing behind it you would turn it to the right.close things up and plug in the washer
if it works with lid closed voila you have fixed it.
Another thing that causes problems are the plastic balls that hold the lid on. They get worn, if the washer starts when you push the lid toward the timer your washer may need new balls.you could try another screw adjust, always un plug power or you will arc the console and scare your self.or worse, you could become deceased. Good Luck.
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Learn the fascinating history of beer, sailing and NYC. Set sail on New York's largest sailing vessel with the craft beer experts from Urban Oyster, and be introduced to the wonderful, reinvigorated world of Craft Beer while enjoying breathtaking close-up views of Lady Liberty and the Brooklyn Bridge. With over 1,500 brewers now making delicious brews all over the country, choosing and appreciating beer has become an art form to rival its cousin wine. Taste several outstanding ales and lagers paired with cheese and charcuterie while you drink in the magnificent views of the skyline of NYC.
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History of the Clipper City:
A replica of the lumber-hauling schooners that drove America's industry more than a century ago, Clipper City was built in the mid-1980s using plans purchased from the Smithsonian. Designed with her new cargo in mind (i.e. you), her decks are spacious and comfortable, with ample seating, a full bar amidships and a raised quarter deck back aft that allows for unparalleled views of the city and its harbor.
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by Jackie Kucinich and Catalina Camia, USA TODAY
Mitt Romney returned to the stage where he once proclaimed himself "severely conservative" to thank thousands of activists for supporting his unsuccessful White House bid.
In remarks Friday to the Conservative Political Action Conference, Romney touted the problem-solving done by GOP governors such as Nikki Haley of South Carolina and expressed his optimism for the future of the conservative movement.
"It's fashionable in some circles to be pessimistic about America, about conservative solutions, about the Republican Party," he said. "I utterly reject pessimism. We may have lost Nov. 7, but we have not lost the country we love and we have not lost our way."
The event known as CPAC often shines the spotlight on the up-and-comers of the Republican Party and is a critical proving ground for presidential hopefuls. More than a dozen potential 2016 presidential candidates - including Sens. Marco Rubio and Rand Paul, Rep. Paul Ryan and Louisiana Gov. Bobby Jindal - are all on this year's program and represent a new generation of Republican leaders.
The emergence of the GOP's new guard is part of what makes the speech by Romney, who turned 66 years old this week, interesting. The other is that during the former Massachusetts governor's two unsuccessful presidential campaigns, he was viewed warily by conservatives for his changing views on issues such as abortion.
Texas Gov. Rick Perry, whose own presidential bid fizzled last year, got in a jab at his 2012 Republican rival during his CPAC remarks Thursday as he criticized the news media for suggesting the losing GOP presidential campaigns of 2008 and 2012 represented a defeat for conservatism.
"That might be true if Republicans had actually nominated conservative candidates," said Perry, who is considering another White House bid in 2016.
Rubio and Paul both called for a new message from their party during their CPAC speeches - one that would attract younger and more diverse voters to the GOP fold. Rubio, who was considered as a possible Romney running mate, even implicitly criticized Romney's dismissal of 47% of the electorate when he said the nation doesn't have "too many people who want too much from government."
In a wide-ranging Fox News interview last week, Romney acknowledged he lacks "credibility" to give advice to Republicans because he lost the 2012 election, but he said he still wants to try to help expand the GOP tent.
(Contributing: Martha T. Moore)
Copyright 2013 USATODAY.com


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Harry Woedy, Bill Stubler, and Bill Gavett show the plaque that bares their names and will be set into the foundation of 355 Campbell Street in honor of their 25 years of volunteer service to Flower City Habitat for Humanity.
- Filed Under
The dedication of Flower City Habitat for Humanity's 188th house, at 355 Campbell St. Tuesday afternoon, honored four men who have volunteered their time with the organization for the last 25 years.
Volunteers Harry Beilfuss, Bill Stubler, Bill Gavett and Harry Woedy have had the Campbell Street home dedicated with a plaque in their names.
"These four men have been with us from the beginning, helping to create the Flower City Habitat we have today," says said Arthur Woodward CEO of FCHH. ...


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Photos of search and rescue effort
EL PASO -- The search for Robert Sumrall, the husband of a former El Paso city representative, yielded no clues Wednesday, four days after he vanished in the frigid and rugged mountains of the Gila Wilderness.
Rescue teams will push for a stronger search with more crews today.
Sumrall, 67, went on a hiking trip with his black Labrador retriever, Zulu, on Saturday morning and was supposed to return to his West Side home that night.
His wife, former West Side city Rep. Jan Sumrall, said he did not return home. Family members filed a missing-person report Sunday, and the search began that afternoon when a heavy snowstorm threatened the search area in the Black Range.
Family said Sumrall left on the hiking trip he has taken before wearing shorts and a sweatshirt. Temperatures Sunday to Tuesday were in the upper 20s and lower 30s, the National Weather Service said. Higher in the mountains, the wind-chill factor is greater. Ten inches of snow fell Sunday on the area, where the elevation ranges from 4,200 to 10,900 feet.
The sky cleared Wednesday, and temperatures rose in Hillsboro, N.M., near the search area, staying in the upper 40s and lower 50s.
Police found Sumrall's sport utility vehicle, a red Hummer H-3, on Sunday afternoon parked at the Emory Pass Overlook near Hillsboro.
About 15 search and rescue members searched on the ground in all-terrain vehicles. And a second helicopter arrived Wednesday to assist.
"They covered all of the most logical trails, and tomorrow they are going to extend it beyond that," said Paige Strait, Robert Sumrall's daughter. She traveled from New York to nearby Silver City to be at the command post and to update her family on the search developments.
Still, the mystery continues over his whereabouts and whether he is alive.
"If anybody could have lasted this long out there, that's my dad," Strait said.
Strait said there was discussion over getting assistance from Fort Bliss, but post officials would not confirm that information.
Officials had told Strait that the search would not continue after Wednesday, but Officer Martin Serna of the New Mexico State Police said the search would resume this morning.
Sumrall is the director of business development for Glacier Technologies LLC. The 4-year-old company, headquartered on the East Side, performs technology, engineering and call center services mostly for federal government agencies.
In the 1960s, Sumrall was a captain in the U.S. Air Force, Strait said. He has two daughters, including Strait, a son, a stepson and a stepdaughter. His wife of 20 years, Jan Sumrall, was the West Side city representative from 1995 to 2003.
Robert Sumrall has lived in El Paso since 1991, when he arrived from Baton Rouge, La.
Adriana Gómez Licón may be reached at firstname.lastname@example.com; 546-6129.


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Phone Scam Warning Issued
Officials with the state Division of Criminal Investigation and the Sweetwater County Sheriff's Department are warning people about a phone scam in which the caller extorts money from people by claiming to be an agent of the federal Drug Enforcement Administration.
Forester Urges Evacuation Readiness
The Wyoming Department of Corrections has issued a comprehensive statewide release policy in response to an April 10th incident where an inmate was released from the state penitentiary in error. Amy Richards has a report. Wyoming State Forester Bill Crapser says wildland fires are likely to be a continuing hazard over the next few weeks and is urging people who may be in affected areas to be ready to evacuate. Click past jump to listen to Wyoming Radio News.
Hay Producers Encouraged to Submit Samples (AUDIO)
New income guidelines are being announced for the special supplemental program for Women, Infants and Children. Amy Richards reports. Wyoming hay producers are being encouraged to submit samples for the state fair in Douglas. Click past jump to listen to Wyoming Radio News.
Park Service Releases Yellowstone Draft [AUDIO]
The National Park Service has released the winter use draft supplemental impact statement for Yellowstone National Park. Amy Richards has details. It looks like there won't be adequate forage for livestock producers this year due to drought conditions. Click past jump to listen to Wyoming Radio News.
Game and Fish Bans Open Fires In Laramie and Lander Regions [AUDIO]
June hay prices in Wyoming in June were well above last year. Amy Richards has the details. With severe drought conditions and local county fire restrictions, the Wyoming Game and Fish Department is banning open fires on all Game and Fish commission-owned and administered lands within the Laramie and Lander regions.
Helicopter Removes Crash Wreckage
According to the Sheriff's Office ,Deputy Sheriff Mike Merkley guided a recovery team from Beegles Aircraft Service of Greeley, Colorado, to the remote scene of a June 22 plane crash on the western slopes of White Mountain about 13 miles north of Green River.
Wind Farm Proposal Clears Hurdle [AUDIO]
A huge wind farm development proposed for southern Wyoming has cleared an important hurdle. Amy Richards reports. Governor Matt Mead says so far it doesn't appear that the wildfires in Wyoming are hurting tourism. Click past jump to listen to Wyoming Radio News.
Finance Committee Sends High West Energy Franchise Agreement to Council
The Cheyenne City Council finance committee voted 2-1 Monday in favor of sending a proposal to grant High West Energy a franchise to continue serving 14 customers within the Cheyenne city limits
State has 1.4 Million Acres in Crop Production [AUDIO]
Results from the annual June Acreage Survey show Wyoming farmers had 1.4 million acres in crop production in June. Amy Richards has details. State officials recently approved a $250,000 grant to improve the events center at Snow King Resort in Jackson. Business Reporter Sharon Fain has details. Click past jump to listen to Wyoming Radio News.
Game And Fish Commission To Meet (AUDIO)
An internal review has found that Wyoming Department of Corrections officials mistakenly released an inmate early even after he told a corrections officer that he still had at least five years left to serve on an aggravated assault sentence. Amy Richards has a report. The Wyoming Game and Fish Commission will meet in Lander next month. Spokesman Al Langston says scheduled topics include license regulations and wold policy. Click past jump to listen to Wyoming Radio News.
City Considering Purchase of "the hole"
The Cheyenne City Council is considering authorizing Mayor Rick Kaysen to negotiate the purchase of the remaining two-thirds of a property on West Lincolnway, commonly known as 'the hole", that is not already city-owned.
Mead Urges Fire Caution (AUDIO)
Governor Matt Mead is urging people to be very careful about anything that could start a wildfire. Mead notes the there is an extreme risk of fire right now, with several large fires burning in Wyoming and other states. Amy Richards has a report. U.S. Agriculture Secretary Tom Vilsack says he wants to increase the number of acres under conservation programs, no matter what happens to those programs in the final food, farm and jobs bill. Click past jump to listen to Wyoming Radio News.


text:
Re: Is this router based on the infineon danube?
Check out http://www.downloads.netgear.com/files/GPL/DGN3500B_16M_V1.1.00.28_src.zip once I looked into it I saw there uboot for amazon se and ar9, and some .asc where there, maybe it will work
Thanks. Tried the u-boot.asc files that were included in both DGN3500 and DGN3500B firmware, and still the same result. And the u-boot/board/ifx/ doesn't seem to have ASE specific stuff.


text:
Last Updated: January 24, 2013 08:34am ET
Office Depot Signs New Lease at Lincoln Sq.
ARLINGTON, TX-The office supply store takes down close to 10,000 square feet as a small-use prototype. More southwest commercial real estate news follows.
You can now be notified via email if this story is updated by clicking on the "Follow this Story" link. You must be a registered member to take advantage of this "members only" benefit.


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Get the latest Flash player
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the great american challenge (allstrange)
my first video of any kind. taking the great american challenge. the huge purple dildo. i must say i really enjoyed it.so take a look and see if you are up to the challenge.
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Top Comment
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Looks like you've got that down to a fine art. Well done. Bet it felt great.
I can finally get all of this in! Check out my video http://www.xtube.com/watch.php?v=4vwx8-G879-
I've just bought this dildo, can get the head in but it sends my insides into shock and my muscles start to spasm so I have to take it out. I'm practicing to loosen my sphincter with the John Holmes which is proving to work well (and feel fucking amazing) want to be able to take the challenge by december
mmm. work that hot hole.
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text:
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Recent studies of limousine company web sites that rank high on Google which have yielded a method for predicting the number of phone calls in any given city.
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Apparently, The Rock has one rock hard body.
Dwayne Johnson aka The Rock took to Twitter Monday to show off his very buff bod and posted a pic on the social media site where his muscle man legs are on full display for his lucky followers.
"Sometimes the most important victories are just for yourself. LEGS. #5KneeSurgeries #RupturedDiscs #StillFindAWay," the Scorpion King actor wrote.
The A-list athlete sported a sweatshirt, gym shorts and tennis shoes for the impressive Twitpic. He posed with his head down and his fist in the air as he flaunted his shocking strength.
The former WWF wrestler plays a bodybuilder in his upcoming flick, Pain & Gain, in which he costars with Mark Wahlberg.
Looks like he's done his work for the role. Keep up the squats, Rock!


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ACTE Outstanding New Career and Technical Teacher
EligibilityIndividuals who are currently employed as full-time classroom/laboratory teachers in a career and technical education program other than at the baccalaureate level are eligible for this award. Nominees must have taught for a minimum of three but not more than five years and must be new to the teaching profession, not just new to career and technical education. Applicants may be in their sixth year of teaching at the time of application. A nominee should have been involved in some capacity in the Association for Career and Technical Education activities at the state, regional and/or national levels and must have been a member of ACTE and a state association at the time of nomination to the Region level.
Application ProceduresEach ACTE awards nominee must first compete in their state and Regional awards competitions prior to being considered for this ACTE member award. All materials must be submitted electronically through the Regional awards committee chairs to the ACTE awards committee (Items 1-6 in one single PDF file, photo in separate JPG file). Regional awards committee chairs can provide application deadlines and other details.
Each nominee shall be evaluated on the following components:
All procedures must be followed for an application to be considered. The completed materials should be submitted to the ACTE prior to the March 1 deadline indicated by all Regions.
InterviewThe interview specifications will be provided to the Region winners/ACTE national nominees.
The deadline is March 1 for states to submit their state winners for Regional consideration. State and Region competition information is listed on the state/Regional page.
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legislators and government leaders.
The Association for Career and Technical Education (ACTE) is the nation's largest not-for-profit association committed to the advancement of education that prepares youth and adults for successful careers. ACTE represents the community of CTE professionals, including educators, administrators, researchers, guidance counselors and others at all levels of education. ACTE is committed to excellence in providing advocacy, public awareness and access to resources, professional development and leadership opportunities.
National Policy Seminar 2016
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November 23rd,
1:00pm to 4:30pm
The wait is almost over! Season 4 of the PBS series Downton Abbey begins in January 2014 and to tide you over, well be screening the last episode of Season 3 and having all sorts of fun chatting about this favorite program. Bring your friends and enjoy games, prizes, snacks, and English tea.
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text:
The World's Biggest Albino Family
A New Delhi albino family of 10 will soon be inducted into the Guinness Book of World Records. Bullied by their neighbors, it's nice to see this family is finally getting some acceptance in this world. Die Antwoord should hire them to be in their next video.
Albino Family From New Delhi Awaits Guinness Fame


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Thanks Suzanne and Mark!
And there she is, that world traveler Flat Ruthie, in Venice on her way in the early morning to the Piazza San Marco ( and a caffe!). She's right across the Adriatic from her Croatian travels. Ps – she LOVED Venice so much she's staying on.


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Indicates new for 2013-2014.
Soybean Science Kit
This kit introduces youth to science in an applied, enjoyable way, highlighting the principles of biology and renewable resources. It demonstrates the concept that agriculture is the business of generating raw materials for consumption, using soybeans as an example. Soybean oils and polymers will be the focus. This complete kit includes a complete curriculum guide, teacher training video, interactive CD-ROM, and supplies needed for a class of 30 students.
Grades 4-9
$415 includes s/h
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Fax: (765) 963-5977
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HURLEY — Things are looking brighter these days for freshman special-needs student Austin Stokes who officials say was assaulted last month at George County High School by a senior.
Stokes has cerebral palsy and was knocked to the ground and hit on the left side of the face so hard the swelling obscured his vision for days. It has been almost a month, and most of the swelling has gone down to a small knot and some bruising.
Stokes and his mother, Lori Ann Dees, decided to move into the East Central school district so he could change schools. Dees said she was unsatisfied with the George County High School administrations response to her sons incident, and students continued to pick on Stokes following the attack.
We certainly respect any parents decision for their child to attend another school, said Debbie Harrell, superintendent of George County Schools. In these cases, we will miss our student and wish him or her much success and hope he/she has a great experience in the new school.
The Stokes have been settling into their new home in Hurley for a week and enjoying the holidays. Stokes will go to his new school Monday. He will be attending East Central High School and said he is happy and excited to start at a new place.
They say in high school, you have to keep watch for yourself, he said.
However, he has plenty of family living in the area and will be attending school with some of them.
Hes got a lot of people looking out for him now, Dees said.
Simple assault charges were filed against the senior who authorities say hit Stokes.
Schools everywhere need to recheck their policies on bullying because the way it was handled was outrageous, Dees said.
Harrell said the school system is committed to ensuring student safety, and the staff and administration provide constant supervision of students and make every attempt to be proactive in dealing with student issues.
Stokes has received an outpouring of love and support from the community, Dees said.
He has received pictures signed by University of Alabama head football coach Nick Saban and NASCAR driver Jimmie Johnson and a signed football from University of Southern Mississippi head football coach Ellis Johnson.
Stokes also received a personal call from country music artist Justin Moore, a favorite of Stokes. Dees said Moore told Stokes to keep his head up and gave Stokes his personal cellphone number.
Stokes has hope for a brighter tomorrow and said he will continue to be involved with ROTC at his new school and wants to join the U.S. Coast Guard one day.


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Staff photo by Curt Youngblood • Lakovion Hill looks at a lizard during a presentation by Andrew Rawlings from Cossatot River State Park during the seventh annual Four States 4-H Day on Thursday. Park interpreters displayed a variety of animals during the presentation.
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text: I would spend the rest of my days traveling if I could. I love to explore new cities and towns, see historical places and things, and sample the foods of other areas. When I'm on vacation, most of my time is spent OUT of the hotel, so I rarely spend a ton of money on accommodations – I'd rather use that cash for tours, meals, souvenirs, things like that. Just once in my life, I'd like to stay at a serious top of the line hotel or resort, and I'd take pretty much any one of the hotels on this list. They all look absolutely amazing. Sadly, the prices would probably make me throw a rod. A girl can dream…….


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Posts Tagged 'Republican Party'
Republican Party Communists
What Allen West Does Not Know About Communists and Congress John Nichols on April 13, 2012 - 8:17 AM ET Florida Congressman Allen West was wrong when he suggested that there were dozens of communists in the current Congress. Misled by crank websites, the out-there Republican from Florida said Tuesday, "I believe there's about 78 to 81 members of the Democrat Party that are members of the Communist Party… They actually don't hide it. It's called the Congressional Progressive ... Full Story
Republican no-sex pledge
GOpers Working hard to Break their own Porn and Sex habits in South Carolina (Video) South Carolina Democratic Party Chairman Dick Harpootlian released the following statement and video in light of the SCGOP's no porn, no sex Party Pledge for the 2012 election: The Laurens County Republican Party is requiring a written pledge by all candidates for state and local office swearing off porn and sex. This requirement is being endorsed by Republican Party Chairman Chad Connelly ... Full Story
Who Would Jesus Vote For?
Should Christians Ask: Who Would Jesus Vote For? By Doug Bandow Evangelical churches long have been called the Republican Party at prayer. The observation might be close to true in Iowa. And that should make American Christians nervous about their future in politics. The relationship of religion and politics has been fraught with controversy since America's founding. In Europe a brutal mixture of church and state harmed both institutions: faith was perverted by power, ... Full Story
Mt. Rushmore After Dark, a conversation of patriots
By Kurt Stone (about the author) opednews.com (The following "conversation" is only partly a product of my imagination; all of the italicized lines represent actual quotes from the four men looking out from Mt. Rushmore . . . ) T. Roosevelt: "Psst . . . Mr. Lincoln . . . Are you awake? In the mood for a chat? I've got a horrific case of insomnia and just know that I'm going to be up all night. I've got a lot on ... Full Story
How the GOP Became the Party of the Rich
The inside story of how the Republicans abandoned the poor and the middle class to pursue their relentless agenda of tax cuts for the wealthiest one percent By Tim Dickinson November 9, 2011 7:00 AM ET The nation is still recovering from a crushing recession that sent unemployment hovering above nine percent for two straight years. The president, mindful of soaring deficits, is pushing bold action to shore up the nation's balance sheet. Cloaking ... Full Story
Boehner and Republicans to support Gaddafi
Blomberg Boehner Says Lawmakers May Seek to Deny Funds for U.S. Operations in Libya By Margaret Talev and James Rowley House Speaker John Boehner said President Barack Obama's explanation of why he can continue the U.S. mission in Libya without lawmakers' approval "doesn't pass a straight-face test" and that lawmakers will consider options to constrain the president, including withholding funds. Read More
War Hawk or Deficit Hawk?
You cannot be both By Michael True "If voting made any difference, it would be illegal," according the late Philip Berrigan. This satiric comment seems especially relevant during our present military and economic crisis President Obama proposes reasonable remedies, but fails to follow through on them, while Republicans issue counter proposals that are bound to make things worse. "If it was not clear before, it is obvious now," according to the New York Times editorial (April 19), that ... Full Story
The Con
Dear Friends and Neighbors: Far be it from me to criticize people who want to start a new party to address concerns in our political system. As far as I am concerned, both major parties are too dependent on big money. They have both abandoned basic respect for others in their campaigning. They both have abandoned logic and reason in favor of emotional appeals. They both act as if they hate the other side. What I can't understand is why the Tea Party should end up supporting the less ... Full Story
B. J. Nikkel accepts the Republican Party's
State Representative B. J. Nikkel accepted the nomination at the Republican Party's House District 49 Assembly on Saturday, April 17, 2010. Eighty-nine delegates and eleven alternates from within House District 49 showed up in Loveland at the Pulliam Building to vote and take part in the Larimer County Republican Party's nomination process. They unanimously supported current State Representative B. J. Nikkel as their nominee. Patrick Albright, Chairman for House District 49 said, "This is ... Full Story


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Third is the intolerable economic situation, with an unemployment rate, in the 18-26 age group, of around 70 percent.
A joke rapper is one thing, but a bad joke rapper is intolerable.
The cost of finding these solutions is manageable; the cost of doing nothing is intolerable.
It was steady work, and it gave her enough to support her family in Mexico, but this year, she says, things got intolerable.
But the occupation itself is an intolerable and constant system of violence.
Why had that innocent and not unfamiliar phrase become so intolerable when she heard it again this morning?
To me he is the most intolerable creature that I ever conversed with.
The evenings were intolerable, and I felt the atmosphere absolutely suffocating at times.
At this intolerable assertion as he deemed it, Edward Gilder was reanimated.
Cicily realized, with an increase of misery, how intolerable had been her conduct.
late 14c., from Latin intolerabilis "that cannot bear, that cannot be borne," from in- "not, opposite of" (see in- (1)) + tolerabilis "that may be endured," from tolerare "to tolerate" (see toleration). Related: Intolerably.


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List of recommended LAME settings, Discussion
List of recommended LAME settings, Discussion
Oct 28 2001, 19:37
Post #1
Group: Members
Posts: 873
Joined: 12-October 01
From: the great wide open
Member No.: 277
The actual list can be found here:
List of recommended LAME settings
This thread is for discussion about the list.
www.High-Quality.ch.vu -- High Quality Audio Archiving Tutorials
Nov 23 2001, 19:26
Post #2
Group: Members
Posts: 94
Joined: 13-October 01
Member No.: 281
Well, here is my offering. I'd like the developers or Dibrom to consider this command line:
--nspsytune --nsmsfix 1.35 --abr 178 -b160 -m j -h --athtype 2 --lowpass 17.5
IMO, it uses only what it needs to achieve a great size/quality result. It's not perfect, but IMO, the vast majority of users would be pleased with the quality from a "casual trade" perspective. This command line has no real artifacts that I can hear, and it's definitely superior to a 192-CBR in my opinion because of it's flexibility. When VBR bitrates get too bloated, I've been using this setting.
Also, it uses a lowpass that conforms to most people's hearing ability. Let's face it, the vast majority of people don't hear much beyond 16 KHz anyway. I've found a 17.5 lowpass allows that little extra wisp of highs which is enough for even a pair of good ears.
It all comes down to what you're willing to sacrifice when the bitrates go below about 192 kb/sec. I put in what I could to maintain quality where it counted in that command line. IMO, if you're willing to go below 192 kb/sec in bitrate, you're not really looking to preserve ulta-high frequencies anyway. So, why not use a reasonable 17.5 KHz lowpass? Makes sense to me. Especially considering it's ABR, not VBR.
|Lo-Fi Version
|Time is now: 26th November 2015 - 02:29


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Effective Communication In The Workplace For The Win
We learn early in our lives that it's better to win, and in order to win, we need to be competitive.
Although this attitude works well in sports, games and personal careers, it can hinder teamwork.
Too much competition can cause team members to constantly try to outdo each other, which can cause added stress, jealousy and conflict. However, just the right amount of competition can boost creativity and foster effective communication in the workplace. Plus, it can motivate team members to improve their jobs.
Read more ›


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Savvy grocers are making inroads against drugstores when it comes to oral care sales.
Children at a very young age learn the importance of proper oral care. It seems as if many grocery retailers are now beginning to learn that lesson as well.
All grocers offer the standard set of toothpastes, mouthwashes and rinses and an array of toothbrushes. However, the opportunity exists to expand the oral care set and include products that shoppers traditionally purchase in other classes of trade.
"Grocery retailers are starting to embrace the notion of having a more diverse set," says Phil Rubin, vice president of marketing for Los Angeles-based TheraBreath. "That is starting to drive consumers, that usually make oral care purchases at the drug channel, to spend more money at grocery."
For example, supermarket sales in the portable oral care segment, in which TheraBreath as well as products such as GlaxoSmithKline's Biotene and Dr. Fresh's Orazyme D are categorized, are up 37.7% in dollars and 36.2% in units for the latest 52 weeks ended February 24, according to the Chicago-based SymphonyIRI Group. Those figures significantly outpace multi-outlet (food, drug, mass and select dollar and club stores) sales, which were up 12.3% in dollars and 11.1% in units.
While it is true the segment is still a small portion of oral care, accounting for a little more than $20 million in a $1.3 billion category, the growth at grocery is significant, because the sales are incremental.
"Traditionally consumers bought brands like TheraBreath at drugstores, but some of the larger grocery formats—Publix, Kroger now has 20 foot oral care sets, Meijer—they are starting to provide a selection that allows shoppers to meet all their oral care needs in a one-stop shopping experience," says Rubin.
Of course the majority of consumers are still visiting the oral care aisle in search of the staples—toothpaste and to a lesser extent mouthwashes and rinses. Industry observers say that because of the nearly 100% household penetration rate of toothpaste it can be difficult for retailers to grow the category. To help, many manufacturers are offering regimen products to stimulate sales.
"Regimen products offer retailers an opportunity to merchandise multiple products at similar price-points to stimulate trial of other forms as well as increase trips to the category," says an official for Cincinnati-based Procter & Gamble. 'We continue to believe that regimen is important to growing the category and to improving shopabillty for the consumer, as the oral care shelf is often hard to navigate."
P&G officials add that in all of the company's upcoming product launches, regimens were developed to work together and deliver an overall oral care benefit to the consumer.
The introduction of new oral care products has always been tricky, say observers. On one hand new products drive trial, on the other, some ask, how many flavors of the same product do retailers need on shelf? As a rule, retailers should look for products that provide value and are linked to efficacy for the oral care shopper, say observers, adding that shoppers are always willing to pay for a product that works well to deliver an unmet need.
P&G says it is meeting those unmet needs with its new additions to the Crest Pro-Health, Crest and Oral-B Pro-Health For Life lines. Crest Pro-Health For Life Toothpaste defends against tooth sensitivity, tender inflamed gums, weak enamel and surface stains. The Oral-B Pro-Health For Life Toothbrush combines CrissCross and Power Tip bristles to help lift and sweep away plaque from hard to reach places. The Crest Pro-Health For Life Rinse defends against tender, inflamed gums from gingivitis, bad breath and plaque that brushing may miss.
"One-third of adults 65 years of age and older have untreated dental cavities and slightly more than 40% have periodontal disease, a form of advanced gum disease," says the P&G official. "The features and formulations of this product line defend against dental conditions people over 50 experience."
Seniors know that taking care of their teeth is a must. At the other end of the spectrum, getting kids to brush can often be a chore for parents. For the past few years Brush Buddies, based in Fontana, Calif., have been positioning the oral care category as "fun" through strategic licensing partnerships.
Brush Buddies recently completed a worldwide music search that allowed fans to vote for the next artist to be featured on the next Brush Buddies Singing Toothbrush. Fans selected Keana and the Keana Singing Toothbrush featuring her name, likeness and two of her hit songs are available this spring. This summer Brush Buddies is expanding its' Poppin' and Talking toothbrush lines to include products that reflect the image, style and voices from The Smurfs 2 movie.
For third quarter, Brush Buddies will launch Brush Buddies Bling Toothbrushes. Jeff Mellin, director of marketing, says they will be available in six "dazzling" colors and each brush will feature hundreds of jewels bonded to the brush handle. Brite Beatz, a synchronized music and light show inside a toothbrush will be introduced in the fourth quarter.
"The Brush Buddies brand provides a range of products that make brushing fun for all ages, characterized by innovative products, healthy margins and retail pricing seen as good value by consumers," says Mellin. "Brush Buddies also has internal systems and staff that manage our retailer-partner assortments to best capitalize on the latest trends in oral care, pop culture, music and fashion."


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In the ZEDfactory article in last week's issue (AJ 14.12.06) the text gave the impression that the project was scheduled to last 35 weeks and had over-run by 32 weeks. In fact, the project had been scheduled to take 67 weeks and took 99 weeks.
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Earnings stripping involves loading up a U.S. subsidiary of a foreign-domiciled company with debt. When the U.S. subsidiary repays the foreign parent, interest payments are deductible from U.S. taxes. The effect is to remove earnings from the U.S., where the corporate tax rate of 35% is the highest in the developed world. Earnings stripping is one of the major benefits of engaging in a corporate inversion and it the target of congressional criticism. Sen. Chuck Schumer (D., N.Y.) on Wednesday said he will propose new restrictions in Congress. Read More »
Aug 14, 2014


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Fun articles and tips by West Paw Design.
There are many reasons why the Boz™ ball is better than a tennis ball for dogs. Boz is a tough dog ball that won't easily break like a tennis ball.
Picky pup? No problem. Create your own unique combination of Toppl tastiness by wedging a tempting treat of your chooing into the dog toy's center. Since Toppl® cleans up easily in the dishwasher, you can dole out different snacks morning, noon, and night. Customizable Toppl makes it possible to please even the most persnickety of pooches.
They become planet saving doggy superheroes of course!
During the month of April we have partnered with our friends at Working Dogs for Conservation. Find out how you too can help these doggy superheroes...
The days of barking at the mailman are slowly becoming a thing of the past, and West Paw Design is embracing the change. Like robotic storks carrying precious cargo, our high-tech drones maneuver through the skies on missions from our Montana headquarters to deliver your order right to your door. They do it so quietly and swiftly you won't even know it has happened until you discover a box full of WPD treasures waiting to be unpacked.
Studies have shown that hair is the feature we notice first when we meet someone new, whether they have two legs or four. Make sure your dog or cat is feeling 100% confident about this most important physical characteristic. Provide your pet with a comfortable, non-toxic, earth-friendly hairpiece from West Paw Design's new line of wigs and toupees.
You may read this title and think, "There is no Zen for the parent of a teething puppy!" True, a teething puppy requires extra supervision and care, but with the right precautions you and your pet can survive the "terrible tooths" with less stress.
A puppy, like a human, will get two sets of teeth during his lifetime. By the time he's around four months old, a puppy will have 28 deciduous teeth or "puppy teeth." He'll have a whopping 42 permanent or "adult" teeth by the time he's around six or seven months old.
Thinking of getting a frisky young dog on this National Puppy Day? Consider visiting an animal shelter or rescue organization. By adopting a puppy from a shelter or rescue, you'll avoid supporting commercial puppy breeding facilities—sometimes referred to as puppy mills or "backyard breeders"—that breed dogs for profit. Need another reason to adopt? Check out our "5 Smart Reasons to Adopt A Puppy" infographic. Better yet, help us celebrate National Puppy Day and share this infographic with your friends.
For those of us who live in regions with four distinct seasons, spring's ample sunshine, welcomed warmer temperatures, and budding trees often come with an ample dose of mud. Rain showers and snowmelt transform the soil into a mucky, messy sludge to which dogs seem helplessly, happily magnetized. Springtime excursions with your favorite canine can be as muddy as they are fun, and, when it's time to go home, some of that mud is inevitably—though innocently—carried by paws and fur back into your vehicle. The pooch doesn't mean to make a mess, but still, the constant cleanup is a hassle.
Do you wonder if adding another pet to your family will result in a house that's full of the hair shed by your four-legged friend? If you'll walk around with an undesired layer of Fido or Fuzzy's fur on all your favorite clothes? Or make a new hobby out of vacuuming? Fear not!
Some dog and cat breeds are known for being minimal shedders, or for not shedding at all, which can make your annual spring cleaning a much simpler endeavor. Here are some low- or no-shedding dogs and cats to consider:


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OK, so it looks like I need to put something in the forums to compete for some of the prizes being offered at the AFK Fest Meetup. Unfortunately, I left my car at home cause it was much cheaper for me to fly - i.e. free! So what should I do. I know, I got it. My entry is the "Car PC in a bag."
Since I travel so much and I like having my Car PC available whether its within the U.S.A or abroad. I have developed a system that gives me most of the capabilities of my own vehicle but is transportable in a shoulder bag and can be used in a rental car, boat, train, plane or in a hotel room.
The Car PC in a bag consists of a Tablet PC and several peripherals depending on where I'm going, and for how long. The main ingredients are an in home power supply with various adapters for overseas use. An automobile power supply with adapters for foreign and domestic vehicles. A 3.5mm male to male cable for plugging my audio out into the vehicles aux-in port. My PCMCIA Cellular card for phone and internet usage. A USB GPS receiver for navigation. A USB FM receiver for listening to local radio. My trusty external DVD/RW in case I run into someone with some great tunes I want to dump on my hard drive. My 8 Mg Pixel camera (that one day I'm going to figure out how to use it as a front recording camera ala Capture!) And miscellaneous cables for the Camera, my Cellphone, USB jump drives, bluetooth dongle, wireless IR keyboard, etc. This may sound like a lot to tote around from jet to jet, airport to airport, but its actually quite compact and travel ready. I have adapted a special bag to house all the equipment (along with a change of clothes) that is an over the shoulder leather Amori Bag (with a lifetime guarantee) that is padded, insulated, and has plenty of pockets and zippered compartments for all my components, pieces, parts, wires, etc.
Unfortunately, when assembled in a vehicle, train, boat, plane, etc, I don't have the luxury of a stealth install. Wires are run wherever I can make them fit without being a hazard. Peripherals have to be hot swapped on occasion to change functions, The tablet rarely mounts anywhere even closely resembling my home automobiles with their sleek docks and hidden wirings. Luckily, most rentals now come standard with a 3.5mm aux-in port and my GPS has a suction cup to attach it to the window. The hardest part to get used to is the touchscreen/pen. I always forget how spoiled I am having a 128 function joystick in my primary vehicles that I hardy ever touch the screen in those cars. With the Car PC in a bag, I have to - bummer! And tapping on the screen while maneuvering the tablet around the gear shift to hold it in place just makes it that much more fun! Needless to say, I know it is about as ghetto an install as they come, but at least it's there and fully functional, well functional, and its better than nothing. or else I never would make it to the AFK Fest Meetup !!!
P.S. Written at 41,000 feet, apx 365knts, using hard writing recognition on the "CarPC in a Bag" while listening to tunes through RideRunner!
HARDWARE: Fujitsu Stylistic ST5111w/WiFi and dock, internal Hitachi 500G HD, external 1TB HD, Sierra Wireless Aircard 550, DVD-RW, BoomzBox HD radio, XM Commander, Delorme GPS, Saitek X-52 Pro joystick, BluSoleil Bluetooth, TPMS, FB, Elm327
HARDWARE: Fujitsu Stylistic ST5111w/WiFi and dock, internal Hitachi 500G HD, external 1TB HD, Sierra Wireless Aircard 550, DVD-RW, BoomzBox HD radio, XM Commander, Delorme GPS, Saitek X-52 Pro joystick, BluSoleil Bluetooth, TPMS, FB, Elm327
i love the idea
now u got me thinking of making a 2nd carputer just for that purpose
if im using a friends car/rental/abroad etc
2006 Mazda6 Carpc
2008 Acura TSX Nexus 7
I love the joy stick.
I love the machine gun feature And the Ice cream man heart attack machine.
A lil Chicago Humor.
New Ipad
Zapco DSP-6SL
Zapco Reference 360.4: H-Audio Soul, x2 right side
Zapco Reference 360.4: H-Audio Soul, x2 left side
Zapco Reference 500.1: JL Audio 10W3V3 Stealth box


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Align the Shades and Sharpen Your Mind with the World's Top Selling Puzzle Game! ONLY Rs.199 for a Rubik's Cube! FREE Home Delivery across India!
- Offer is on a Rubik's Cube
- Improves memory and concentration
- Exercises the mind and leads to better hand-eye coordination
- It is the world's top selling puzzle game
- Size : 6*6*6cms
- Free delivery across India
- Inclusive of all taxes and service charges
For more than 20 orders, please write to firstname.lastname@example.com to get additional discounts! Yes! Above the crazy discount you already see!
Warranty Terms:
- Given the nature of the product, there is no warranty
- Crazeal Promise: We offer a 7-day no-questions-asked replacement guarantee if your product is found to be damaged/defective on arrival
Delivery Timeline:
- Expect the product to reach you within 10 days of order
- It takes this long because you don't get these prices every day!
- Over 75% of our shipments reach within 5 days. But we would much rather under-promise and over-deliver!
COD Charges:
- Rs.50 COD charge for total transaction of Rs.499 and below
- FREE COD for total transaction of Rs.500 and above
- We suggest you check out other awesome deals in your
city to waive it off!
See the rules that apply to all deals
Life is like a Rubik's Cube – colorful and confusing! While we can't give you any lessons on life, we can help you get your hands on a Rubik's Cube so you can have fun aligning the colors!
No matter what your age – this amazing puzzle has a lot of benefits aside from being a great way to pass time. It strengthens your mind, improves short-term memory, leads to better hand-eye coordination and concentration.
Here are some fun facts about the cube:
- It was initially called the 'Magic Cube'.
- The Cube has inspired everything from fashion, architecture and music to films, plays and political speeches
- The current world record for a single solve was set in June 2011 at the Melbourne Winter Open competition in Australia, by Feliks Zemdegs with an incredible time of 5.66 seconds!
Twist, turn and slide! Pay just Rs.199 instead of Rs.255 for a Rubik's Cube and have it delivered right to your doorstep for FREE!


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(idiom) have a reason to be angry with a person
Example Sentences:
A: Richard?
B: Yes Mom?
A: I have a bone to pick with you. If you are going to be late, could you please call me?
B: Okay.
Dusty's roommate had a bone to pick with her because she was really messy and never cleaned up.
From the Blogs:
I have a bone to pick with stupid parents


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- Filed Under
NEWARK -- Area bowlers were shocked when Valley Lanes closed without notice in July.
Less than three months later, the doors are opening again. Valley Lanes was closed after more than 50 years in business at the start of July by its owner, AMF Bowling Centers.
AMF, however, is now out from its lease, and Valley Lanes is re-opening next week as an independent business, according to general manager Michael Alfano, who had worked at Valley Lanes the past two years after previously working for AMF. ...


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Taking a Music Break: Radiohead "Lotus Flower"Juxtapoz // Friday, February 18, 2011
We have received over 10 emails this morning asking 1) have we watched the new Radiohead video for "Lotus Flower," and 2) have we listened to the early release of The King of Limbs? Yes and yes. And because it is Friday, take a break, watch the new video, and think of Stanley Donwood's Works On Paper show opening at Lazarides' The Outsiders last night in London. Video after the jump . . .


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The Palace Special ($12.70 to $20.20) at Pagliai's Pizza is topped with sausage, beef, pepperoni, mushroom and onion. / Alesha L. Crews / Iowa City Press-Citizen
Pagliais Pizza
Address: 302 E. Bloomington St., Iowa City.
Phone: 351-5073.
Hours: 4 to 11 p.m. daily.
Price: $7.70 to $20.20.
Information: www.pagliaisic.com.
As a newcomer to Iowa City, friends quickly recommended dozens of restaurants that I had to try. For the last year and a half, Ive been working my way through the list and discovering my own favorite places along the way. As part of my journey, I made a long-overdue trip to Pagliais Pizza in Iowa City last week.
ATMOSPHERE: To say walking into Pagliais Pizza is like stepping back in time is as cheesy as the restaurants pizza ... but the classic, old-time feel definitely changed my perspective for a couple of hours.
The small restaurant which offers both dine-in and carry-out options is lined with black booths, wood tables and minimal decor. The carpet, low-ceilings and patterned wallpaper give the restaurant a homey feel.
The open kitchen which gives diners a view of the assembly line of pizzas being prepared offers free entertainment and a look at the care employees, dressed in crisp white shirts and paper hats, put into each pie.
My waitress was friendly and attentive the entire evening.
MENU: The restaurants focus is on producing its traditional thin crust pizza. There are no appetizers, no desserts and little wiggle room when it comes to its pizzas (there are two crust options and just one sauce). That said, the pizza shop offers two specialty pies and more than a dozen toppings to choose from if you prefer the build-your-own option.
The restaurant serves a variety of soda and wine along with a handful of beers, coffee, ice tea and milk.
WHAT I TRIED: I ordered the Palace Special pizza ($12.70 to $20.20), which is topped with sausage, beef, pepperoni, mushrooms, onion and cheese. The crust was thin and crisp and gave each bite a bit of crunch. Toppings were evenly distributed over the pizza not piled high on top of each other and covered in a thin, layer of cheese. The housemade tomato sauce was smooth and savory, and each of the toppings was fresh and flavorful. My favorite was the sausage, which is seasoned in house because it added just a hint of heat to each bite.
Shakers filled with garlic salt, Italian herbs and dried red pepper flakes are on each table for customers who want to add more flavor to their slices.
BOTTOM LINE: When it comes to traditional thin crust pizza, it doesnt get much better than Pagliais.
Reach Alesha L. Crews at firstname.lastname@example.com or 887-5414.


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Texas vets support Toys for Tots
SAN ANGELO, Texas - Toys for Tots collected its final donation from Texas Veterans for Veterans during its toy distribution of nearly 20,000 toys to less fortunate children of the Concho Valley this Christmas.
Texas Veterans for Veterans (TVFV), established only two years ago, has high hopes this holiday season of making a lasting impact in San Angelo and the Concho Valley. More than 100 members of this fairly new organization came together in support of Toys for Tots, dropping off bicycles and a check for $500 at the warehouse amid the distribution of toys only days before Christmas. Their mission: help vets and the next generation of our community. Recently, TVFV gave nine $500 scholarships to seniors in San Angelo to help with first-year college expenses. Now, several members stand next to the Marines in support of Toys for Tots.
Among those members was Joe Miloni. Joe served in the Marine Corps from 1948-1974, and fought in both the Korean and Vietnam wars. Shortly after coming back from Korea, Joe volunteered for Toys for Tots in Norfolk, Va., in 1952 and 1953.
"Toys for Tots was a little different back then," Miloni said. "We collected old, broken toys and worked very hard to restore them to the new, shiny toy that every child wants for Christmas."
Almost 60 years later, Miloni is excited to be back helping children experience the joy of Christmas.
Marine students from Goodfellow Air Force Base, volunteering at the warehouse, enjoyed the visit from heroes of past wars. What a great way to end the year. Marine veterans spanning 60 years standing side-by-side to make a difference in a child's life this Christmas is a great picture of generations of Marines still giving their all for this great nation.
Toys for Tots ended its 2012 campaign by distributing almost 20,000 toys to over 4,000 children this Christmas. The Marines assure that, despite a few small changes for the 2013 campaign, they are committed to helping the less fortunate children of our community.
Staff Sgt. Joshua Lay, USMC, is a Toys for Tots coordinator.
Subscribe to the San Angelo Standard-Times
Need Help? Call us at 1-877-304-7763.
Monday-Friday: 6am-8pm / Saturday: 6am-12pm / Sunday: 6am-1pm


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Reports: TNA won't get new deal from broadcast partner
TMZ is reporting that Nashville-based TNA Wrestling has been informed by Spike TV that its premiere show, Impact, will not be renewed when its contract is up in October.
A Spike spokesman told Post Sports "we don't comment on ongoing negotiations," which at least insinuates that it's not necessarily a done deal (or that it's a deal not ready for public consumption). TNA did not return a request for comment.
Spike has aired Impact since 2005 and while the promotion has had some success — it averages about 1 million viewers per week — it's failed to make much of dent in industry leader WWE. (TNA is reasonably popular and even competitive with the WWE in certain overseas markets, though, particularly in Europe and south Asia.)
Despite rising new competition from former TNA impresario Jeff Jarrett, who launched his own Global Force Wrestling this spring and already has partnerships with some of the top overseas promotions (such as New Japan and Mexico's AAA), TNA is still regarded as the clear No. 2 wrestling promotion in the U.S. (Of course, you could drive a billion Andre the Giants in the hole between 1 and 2.)
From recently retired WWE announcer (and hopefully future Fox Soccer play-by-play man) Jim Ross:
Obviously, this is a blow to TNA but they have a weekly audience of approximately 1M viewers which will interest some cable networks. The question is can TNA negotiate a deal that will financially keep them in business in today's entertainment world with this quick turnaround?
WWE got less of a rights fee from NBC/Universal to stay on the USA Network than many predicted so one could assume another cable entity might not be willing to pay top dollar for TNA with the current perception that broadcasters apparently have regarding the genre.
One would assume/hope TNA finds a new cable home and they move their fan base with them. If not, Viacom's Spike Network is in the same position TBS was in when Jim Crockett Promotions found themselves in financial duress. TBS bought out JCP and WCW aired on TBS & TNT for years. The question is does Viacom want to own a pro wrestling franchise to go with their newly acquired MMA franchise Bellator?


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LISBON – An Ogdensburg woman was jailed on burglary and assault charges early Saturday morning after allegedly smashing an apartment door and assaulting the occupants, according to St. Lawrence County sheriff's deputies.
Deputies charged Sierra R. Herbick, 22, 819 New York Ave., Ogdensburg, with burglary second degree, assault third degree, criminal mischief fourth degree, and criminal contempt second degree.
Deputies responded about 2:30 a.m. after Brian McDonald, 1060 County Route 28, reported that Herbick and Eric R. Miller, 20, of 706 Bigelow St., Ogdensburg, had smashed the door to his apartment in and assaulted him and a guest, Susan Bogart.
The door and casing were damaged, deputies said.
The criminal contempt charge against Herbick is for her alleged violation of an Order of Protection issued by Ogdensburg City Court on March 3, ordering her not to assault or harass McDonald, deputies said.
The injuries suffered by McDonald and Bogart are considered minor, deputies said. Herbick was taken before Canton Town Justice Thomas Wheeler and sent to St. Lawrence County Correctional Facility in lieu of $2,500 cash or $5,000 bail bond, deputies said.
Deputies said they are still searching for Miller. Those with information about Miller's location are asked to call the sheriff's office at 379-2222.


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PHOTOS: Bowe Bergdahl released after 5 years in captivity
WASHINGTON, DC - MAY 31: President Barack Obama makes a statement about the release of Sgt. Bowe Bergdahl as his parents, Jani Bergdahl (L) and Bob Bergdahl (R) listen May 31, 2014 in the Rose Garden at the White House in Washington, DC. Sgt. Bowe Bergdahl was held captive by militants for almost five years during the war in Afghanistan. (Photo by J.H. Owen-Pool/Getty Images)
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I'm planning our food for a upcoming trip. Sure would be nice to create a fantastic, surprise meal. I have a dehydrator. Sarah,what's the latest, hottest, best recipe idea your trail chef mind can conjure?
George, you have to give her a hint. There's only about a million great recipes out there, and she only knows half of them.--B.G.--
Tell me what you love and what you hate ;-)
When I plan backpacking menus, they're sorted into 2 categories: nacho taters and everything else.If you do a search for "nacho taters" and "curried chicken cranberry couscous" on this site you'll find 2 great recipes. Plus both threads have other terrific offerings.
http://www.trailcooking.com/recipes/curried-chicken-cranberry-couscousI love that recipe - it is very simple.
I like Sarah's Cranberry Chicken Rice (Freezer Bag Cooking, p.44). One of my favorites.Her curried-chicken-cranberry-couscous or the rice will definitely be one of the meals. (http://www.trailcooking.com/recipes/curried-chicken-cranberry-couscous)Now back to the meal I want to create for my better half. Here is a Rachael Ray recipe that she really likes. I'd like to make a trail version of it...INGREDIENTSSalt1 pound bucatini [change to Barilla farfalle pasta]Extra virgin olive oil (EVOO), for drizzling, plus 1 tablespoon8 slices smoky bacon, chopped3-4 spring Vidalia onions with a few inches of green tops intact, very thinly sliced or 2 leeks, halved lengthwise, thinly sliced, then washed and dried4 cloves garlic, grated or finely chopped1 red chili pepper, seeded and finely chopped or 1 jalapeño or red Fresno pepper, seeded and finely chopped2 pints ripe cherry tomatoes1/2 cup dry white wineBlack pepper1/4 cup flat leaf parsley (a couple of handfuls), choppedA handful of basil leaves, torn or shreddedA generous handful of grated Pecorino cheese, plus some to pass at tablePREPARATIONHeat a large pot of water to a boil for [farfalle], season water with salt then cook pasta to al dente.In a deep skillet or Dutch oven with tight-fitting lid, heat a drizzle of EVOO over medium-high heat. Add the bacon and cook until crisp; remove the bacon with a slotted spoon and reserve on a paper towel-lined plate. Drain off some fat if the pan has more than a couple of tablespoons of drippings. Add the sliced spring Vidalia onions or leeks, garlic and hot pepper and sauté for 2-3 minutes, then add the tomatoes and stir to combine; cover the pan. Shake the pan occasionally and cook until the tomatoes begin to burst, 6-8 minutes. Uncover the pot and mash up the tomatoes with a wooden spoon, add the wine and stir for 1-2 minutes. Season the sauce with some salt and black pepper, to taste, then reduce the heat to low.When the pasta is ready, add a ladle of the starchy cooking water to the sauce along with the parsley, bacon and bucatini and toss for 1-2 minutes with an extra tablespoon of EVOO. Turn off the heat and toss in the basil and cheese; serve immediately.http://www.rachaelray.com/recipe.php?recipe_id=3321
Dang,I want that for dinner tomorrow!And yes...that could be translated to a one pot meal using a quick cooking pasta like the mini Barilla pastas that cook in 7 minutes. You have me thinking!
How was it?Keep that thinking going. : )
I am working on it :-) I got busy this weekend coming up with new recipes for my REI presentations this week....then back to the drawing board!
This weekend is going will be dehydrator mania for me. Dry baby dry!I'm finalizing my food for an upcoming five trip.Will share my results.
Cool! Do share :-)
For I am weak.Was really going to work hard all weekend drying and putting recipes together. Had the trail cookbooks ready. Was pumped. Ready to work.Then my son and I decide to hike Saturday. That's all it took. Yes, I am weak.So by Sunday night. I thought:; yikes!So I bought some tasty sounding meals (mostly Mary J). Filled up some bags with nuts. Oatmeal. Trader Joe Honey Roasted Sesame Sticks, good looking breakfast pastries. Raisins. Healthy snack bars. Plenty of food.Maybe next trip I can gather the strength to put the necessary effort into my trail food. Don't give up on me. How this for sharing : )Respectfully,Sir Slacker-alot
Lol....the Food Industry of America thanks you ;-)
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