text:
|Simple and effective 3D recognition of domoic acid using a molecularly imprinted polymer.
MedLine Citation:
|PMID: 17935328 Owner: NLM Status: MEDLINE
|We have developed a simple and effective molecular imprinting technique to target compounds with flexible structure. Domoic acid (DA), an amnesic shellfish poison, was used as the target compound while many acidic compounds (mono-, di-, and tricarboxylic acids) were used as template molecules for molecularly imprinted polymers (MIPs). Evaluation of selective recognition abilities using liquid chromatography revealed that the highest selective recognition ability for DA was found when pentane-1,3,5-tricarboxylic acid (1,3,5-PeTA) was used as the template. Computer modeling studies of the DA structure suggested that the observed selective recognition depended on the structural changes in DA at the recognition site of the MIPs as well as spatial distance between the COOH groups in DA and 1,3,5-PeTA. Using the 1,3,5-PeTA-MIP, we could easily purify DA from blue mussel extracts by solid-phase extraction.
|Koji Nemoto; Takuya Kubo; Makoto Nomachi; Tomoharu Sano; Takatoshi Matsumoto; Ken Hosoya; Tetsutaro Hattori; Kunimitsu Kaya
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Publication Detail:
|Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-10-13
Journal Detail:
|Title: Journal of the American Chemical Society Volume: 129 ISSN: 0002-7863 ISO Abbreviation: J. Am. Chem. Soc. Publication Date: 2007 Nov
Date Detail:
|Created Date: 2007-10-31 Completed Date: 2008-01-11 Revised Date: -
Medline Journal Info:
|Nlm Unique ID: 7503056 Medline TA: J Am Chem Soc Country: United States
Other Details:
|Languages: eng Pagination: 13626-32 Citation Subset: IM
|Graduate School of Environmental Studies, Tohoku University, Aoba 6-6-20, Aramaki, Aoba-ku, Sendai, Japan.
Export Citation:
|APA/MLA Format Download EndNote Download BibTex
|MeSH Terms
Chromatography, Liquid
Hydrogen-Ion Concentration
Kainic Acid / analogs & derivatives*, chemistry
Models, Chemical
Molecular Conformation
Molecular Imprinting
Pentanes / chemistry*
Polymers / chemistry*
Sensitivity and Specificity
Tricarboxylic Acids / chemistry*
Reg. No./Substance:
|0/Pentanes; 0/Polymers; 0/Tricarboxylic Acids; 109-66-0/pentane; 14277-97-5/domoic acid; 487-79-6/Kainic Acid
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Extended sugar-assisted glycopeptide ligations: development, scope, and applications.
Next Document: Molecular dynamics simulations of the catalytic pathway of a cysteine protease: a combined QM/MM stu...


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100% Polyester
November 27, 2014
A christmas present so untried, but it was good to find the very large size in a bright colour. looks like it will be light to wear but warm.
November 26, 2014
Used for some time now.
wearing well, washing well, very pleased with purchase
October 26, 2014
Versatile and hard waring.
October 25, 2014
Great outdoors ware, good size, warm and comfy
Washes really well, comfortable to wear and easy to maintain.
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A Plateful Of Our Dead guitar pro by Protest the Hero, added: September 27th, 2007
Profile History
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Wow.. a total rip off of my tab. Lol.. all you did was either change where the note was played or just changed the
notes to make it wrong. Bravo!


text:
EGO-T Starter Kits Becoming More Popular
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Here is a video review of the EGO-T Starter Kit from Smokeless Delite-
EGO-T Kits At Low Prices
SmokelessDelite offers our premier EGO-T Kit that comes with the eliquid nicotine e-juice and everything you need to get started with your serious vaping needs. We also provide a variety of eliquid e-juice flavors for you to choose from. We will also be adding a variety of flavors and nicotine levels for you to choose from in in the future. If you have a specific flavor in mind, please do not hesitate to send us an email. We will be happy to take your flavor into consideration and add it to the wide variety of liquid nicotine flavors to choose from. We also offer a wide variety of EGO-T Accessories for you to choose from. We currently have the EGO-T Tank atomizer for you to make filling up your liquid nicotine easier and it has the capacity to allow you to fill more eliquid in your tank cartomizer. This is a great benefit because it offers vapers the ability to vape more without having to fill up and having to recharge their battery. We are taking into consideration many other EGO-T accessories like the lanyard for letting your personal vaporizer hang around your neck.
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See All Contributors »
Here are some of my thoughts from today's press conference. A few miscellaneous tidbits as well.
Williams Blog: A new season begins Wednesday | Cyclone Fanatic
Twitter: @ChrisMWilliams
Facebook: Cyclone Fanatic
Sounds to me like the chemistry problems are starting to get solved... i think this will help them play with more intensity
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Amazon streaming device rumored to be dongle offering game streaming
updated 04:08 pm EDT, Mon March 17, 2014
Chromecast-like dongle from Amazon could offer high-end gaming
Amazon's rumored media streaming device may have more in common with the Google Chromecast than previously thought, according to a report. The retailer is said to be making the media player in the form of a dongle that can plug directly into a television's HDMI port, with one rumor claiming that it would have the ability to stream high quality games from a server, instead of relying on modified mobile titles for gaming.
Sources of TechCrunch claim it will offer a similar service to OnLive, streaming games over the Internet at 30fps, instead of the in-home streaming offered by the Nvidia Shield. Streaming games made for PC or Mac, such as titles sold through Amazon's download store, would in theory allow the device to compete against current-generation game consoles, such as the Microsoft Xbox One and the Sony PlayStation 4.
Google Chromecast
Previous rumors in January suggested Amazon was working on a sub-$300 Android game console, while in February the retailer acquired Double Helix Games, the game studio responsible for Killer Instinct for the Xbox One. Over the weekend, images of what are claimed to be Amazon-branded game controllers surfaced in Brazilian regulatory documents, showing a device with typical game controls and triggers, as well as a row of media buttons.
As with previous long-time Amazon hardware rumors, it is difficult to estimate a release date for the system, if it exists. It is even possible that the device being reported on is just one of a number of potential designs Amazon is looking into producing, and could still wildly differ before its release.


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|Star Trek Movies XI+ Discuss J.J. Abrams' rebooted Star Trek here.
|Thread Tools
|September 29 2013, 11:51 PM
Lieutenant Commander
Why didn't Spock set the self-destruct?
|September 30 2013, 12:08 AM
Vice Admiral
Location: Flying Spaghetti Western
Re: Why didn't Spock set the self-destruct?
But then, there's all kind of things they overlooked.
I always wondered at exactly what point Marcus and Khan stopped being allies. By extention, I wondered why Khan beamed to Kronos at all.. was he personally interested in having the Federation start a war with the Klingons? These two questions seem unconnected at first, but once you look at the plot, story, and details, you realized that certain plot elements were not worked out.
Also, I know that 72 was the number that the writers had been handd on a silver platter from the original episode, but it's an ungainly number. It would require more torpedo launchers than the Enterprise has (until the CG people had aplaced a few on the side but not nearly enough) and it was too much for Spock to have people take out the cryo-tubes and install explosives.
I watch the film for the performances.
No more adventures! I'm not going that way!
|September 30 2013, 12:11 AM
Re: Why didn't Spock set the self-destruct?
Then there's the possibility that he calls Spock's bluff, destroys the Enterprise for the Hell of it and then is wondering the galaxy in a floating WMD platform that is three times faster than any other ship in the Fleet.
I think Spock made the right call.
"If we're going to be damned, let's be damned for what we really are." - Jean-Luc Picard, "Encounter at Farpoint"
|September 30 2013, 06:41 AM
Vice Admiral
Re: Why didn't Spock set the self-destruct?
* * *
Well, I've been to one world fair, a picnic, and a rodeo, and that's the stupidest thing I ever heard come over a set of earphones."
|September 30 2013, 06:49 AM
Location: RIP Leonard Nimoy
Re: Why didn't Spock set the self-destruct?
- SeerSGB -
|September 30 2013, 06:55 AM
Director of Comedy
Location: Either on the Normandy SR-2 or in the Sirius Sector Block
Re: Why didn't Spock set the self-destruct?
Many thanks to Nerys Myk for my awesome avatar!
Check out the Caption contests in the TOS, TNG and Movies I-X forums!
|September 30 2013, 06:59 AM
Vice Admiral
Location: Knoxville, TN USA
Re: Why didn't Spock set the self-destruct?
Admiral Marcus and Khan were never allies. Marcus was holding the other 72 Augments as hostages to ensure Khan's cooperation with him and Section 31. Khan found them, and tried to hide them by placing their cryotubes inside torpedo casings. But Marcus figured out what Khan was doing and he took the tubes. Khan went apeshit when he thought Marcus had killed his "family," and that's why, after his attack on Starfleet which resulted in Pike's death, yes, Khan went to Kronos to start something between the Klingons and the Federation. He changed his mind once he'd realized that the cryotubes were still inside the torpedo casings where he'd left them.
Even if Marcus had gotten Khan to agree to help him without resorting to extortion, I expect that Khan would have betrayed Marcus anyway, just as soon as the usefulness of their faux alliance had run out. Not unlike what he does with Kirk later on.
|September 30 2013, 08:12 AM
Rear Admiral
Re: Why didn't Spock set the self-destruct?
I mean, with the torpedoes Spock wins the engagement, with the self-destruct both parties are in a gridlock at best. Even the chance of it not working is better - Khan is more likely to take his people unsuspecting, than he is going to be willing to accept Spock's treat to use self-destruct.
Also the self-destruct that blows all the people up is one of the ideas that I can hardly imagine ever seeing in real life. It might be a good idea sometimes, but no person today, much less in the bright utopian future, would ever sign under a document mandating one. Not seeing a self-destruct plot only makes the film slightly more realistic than what we've seen before.
Not to mention than a bad guy getting his friends (not guilty of any present-day crime) back from the ship probably hardly justifies using it under Starfleet regulations.
Objects in mirror are bluer than they appear
|September 30 2013, 04:19 PM
Vice Admiral
Location: Flying Spaghetti Western
Re: Why didn't Spock set the self-destruct?
All I can say is.. it is confusing isn't it?
- We don't know if they were allies, or if Khan knew from the start he was being used. Supposedly Khan is pretty smart.
- We don't know why Khan went to Kronos.
- We don't know how that many torpedoes can change hands so fast.
- We don't know how Marcus found out that Khan placed the men in the torpedoes (but he did know about it)
No more adventures! I'm not going that way!
|September 30 2013, 04:29 PM
Rear Admiral
Re: Why didn't Spock set the self-destruct?
It was the best of Trek, it was the worst of Trek...
"If I lean over, I leave myself open to wedgies, wet willies, or even the dreaded Rear Admiral!"
|September 30 2013, 04:42 PM
Vice Admiral
Location: Flying Spaghetti Western
Re: Why didn't Spock set the self-destruct?
No more adventures! I'm not going that way!
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