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Excellent Explosions and Extreme Extrusions in C4D
In this tutorial, Carlos will teach us how to create extruding text exploding out of a box using C4D. We'll then bring it into After Effects to add more particles and a background. This is excellent effect to go through if you've been wanting to try a 3d program.
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Want to follow your favorite teams live on your smart phone, tablet or desktop? With our new PrimeTime viewers you can do just that!
Click into your favorite team's schedule and the Live Stats links will take you to our new viewers which are responsive for any device you're using.
The Live Stats link is now unique to each event so you can get to your games faster and easier!
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JSR Related Items on Java.net
This JSR specifies the OSS/J SQM API.
Test Application Signature Safety - analyze static references
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Scripting Engines and Scripting Applications.
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The OSS Fault Management API public project
This JSR specifies the set of APIs which are common across OSS/J
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The original Facelets projects. Note active development is done at http://javaserverfaces.java.net/
This JSR defines an interface to an Order Management component.
OSS/J extensions for TMF MTNM
David Sean Taylor, an open source software developer has been involved with developing Jetspeed for almost four years now. He talks to the Portlet Community's Navaneeth Krishnan him about Jetspeed and the Portlet spec detailed in JSR 168.
November 22, 2004
Java(tm) Scientific Library. Version 5.0 release in progress. Snapshot versions of the mathematics, physics bundles currently available (https://maven.java.net/index.html#nexus-search;quick~jscience)
JSR 133 produced a formal mathematical specification for the semantics of synchronized, volatile, and final. It provides the foundation for (finally) delivering on Java's promise of being able to develop write-once, run-anywhere concurrent applications.
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Description of concurrency utilities provided by JSR 166.
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The introduction of enums, generics, and metadata are changes to the Java language that require modifications to existing APIs, such as Reflection. This article examines the modifications to the Reflection API that are now available to the public as part of JDK 1.5 beta 1 and shows how you can take advantage of them in your code.
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Get the longest life out of your hot tub! Our tips make maintenance easy!
How to Remove a Stuck Hot Tub Filter
How to remove a stuck hot tub filter is a question The Cover Guy staff receives all to often so we thought in this post we would let you know the best ways to remove a stuck hot tub filter, and the best ways to avoid having your hot tub cartridge filter being stuck. Hot tub filters especially the threaded versions do become stuck. They become stuck for a few reasons they are often installed to tightly, not changed enough and crust over with deposits. The first thing you must do is turn your power off, sometimes that is all it takes. the...read more
New Hot Tub Cover for the Fall and Winter
As the summer is winding down there are steps you can take to prepare your hot tub to be more efficient for the Fall and Winter months ahead. One of the best ways to prepare is making sure you have an appropriate hot tub cover to carry you through the colder months of the year. Hot tub covers traditionally last 3 – 7 years based on climate and use.If your hot tub cover or spa cover is not up to the challenge to go through a winter, you will significantly increase your cost for running the hot tub. Most hot tub owners know when their hot...read more
Hot Tub Power Pak Repair
Hot Tubs are great for relaxation, but when you have an issue it can become stressful not knowing why your hot tub has stopped working. If you are having problems with your power pak tripping and turning off, you can identify and repair the issue yourself with a little detective work. A hot tub will trip for a number of reasons from as simple as a dirty filter to a ceased pump. Whatever the issue you can always repair a hot tub power pak. The first thing I like to do is to make sure I know what is causing the issue. First things first, Clean...read more
Jacuzzi Hot Tubs Error Codes & Information
Jacuzzi Hot Tubs and Spas The family behind Jacuzzi Hot Tubs & Spas first made an aerating pump for hydrotherapy in the 1950s, and they began manufacturing hot tubs two decades later. By the '90s, these hot tubs had expanded into backyard models, and the award-winning company spread out into the international market by the year 2000. The company holds more than 250 patents worldwide, including the first patent in the world for a whirlpool bath. Their models feature eco-friendly and advanced hydrotherapy options, and Jacuzzi Hot Tubs...read more
How to change the Filter Mode on a Dream Maker Spa
How to change the pump and filter mode setting on a Dream Maker spa or hot tub has come up a few times with our customers so we thought we would offer this post to guide you through the process. The Dream Maker spas use a Balboa topside control. The Dream Maker spa gives you many options as far as filtration and heating to chose from there is the factory set Standard mode (ST) and the most used setting which has the heater come on as needed to keep your desired temperature. The Economy Mode (EC) which has the heater come on during scheduled...read more
Leisure Bay Spas Hot Tubs & Information
Leisure Bay Spas has been building hot tubs for over thirty years and has a range of hot tubs built on quality and new innovations in the hot tub market. In the Elite series Leisure Bay Spas boasts 4 different models the Niagara, Hatteras, Cordova, and Harbor Cove. The Celebrity series has the following five models to choose from the Tonga, Santo, Hilo, Adirondack, and Galaxy. The Cover Guy custom makes replacement Leisure Bay Spas hot tub covers for all of the above . Leisure Bay Hot Tub Error Codes These are the error codes and display...read more
Beachcomber Hot Tubs Error Codes & Information
Beachcomber Hot Tubs Beachcomber Hot Tubs from Surrey, BC have been manufacturing and selling spa products since 1978. The company offers a 30-day money back guarantee on their products, and they also offer many innovative design options such as the Hybrid3 and custom jetting. One of the main focal points of Beachcomber Hot Tubs is producing products that are as energy efficient as possible. According to an independent testing company, Beachcomber has met this metric by manufacturing hot tubs that cut energy bills by more than 30 percent when...read more
Cal Spas Error Codes & Information
Cal Spas Cal Spas was founded in 1979, and they currently offer more than 250 product models. Each of their hot tubs can be customized from a list of thousands of options, and the company places an emphasis on innovative touches and quality workmanship. Cal Spas is based out of California, and they have earned an A+ Better Business Bureau rating. Cal Spas focuses on offering home resort experiences, and they have been honored with numerous industry awards. The company's products are also TradeCertified, meet the UL Certified standard of...read more
Bullfrog Spas Error Codes & Information
Bullfrog Spas Bullfrog Spas is part of Bullfrog International, and they have been making hot tub products since 1996. The company is based out of Utah, and each of their designs features their patented JetPak Therapy System. This technology gives users the option to upgrade, interchange and customize the jetted massage that their hot tub provides. With the JetPak system Bullfrog Spas is unique in an industry that has very little uniqueness. Bullfrog Spas products are sold in numerous countries. The hot tubs are designed with hydrotherapy and...read more
Arctic Spas Error Codes & Information
Arctic Spas Arctic Spas has been manufacturing innovative hot tub designs for more than 20 years. The owners take a small town approach to delivering products that are high quality because they all have roots in rural Canadian communities. This manufacturer places a big emphasis on making hot tubs that require a minimal amount of maintenance and are more cost-effective to operate than other major brands. Arctic Spas products can be found at a wide variety of dealer stores throughout the U.S. and Canada, and it is common for these locations to...read more


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|Publication number
|Publication type
|Application number
|Publication date
|4 Jan 2005
|Filing date
|26 Dec 2001
|Priority date
|26 Dec 2001
|Fee status
|Publication number
|Matt Chludzinski, Eric Hammill
|Original Assignee
|Advanced Cardiovascular Systems, Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (26), Non-Patent Citations (17), Referenced by (36), Classifications (12), Legal Events (3)
|External Links: USPTO, USPTO Assignment, Espacenet
The invention relates to the field of intraluminal catheters, and particularly to guiding catheters suitable for intravascular procedures such as angioplasty, stent deployment, pacing lead deployment and the like.
In percutaneous transluminal coronary angioplasty (PTCA) procedures, a guiding catheter having a shaped distal section is percutaneously introduced into a patient's vasculature and then advanced through the patient's vasculature until the shaped distal section of the guiding catheter is adjacent to the ostium of a desired coronary artery. The proximal end of the guiding catheter, which extends out of the patient, is torqued to rotate the shaped distal section and, as the distal section rotates, it is guided into the desired coronary ostium. The distal section of the guiding catheter is shaped so as to engage a surface of the ascending aorta and thereby seat the distal end of the guiding catheter in the desired coronary ostium and to hold the catheter in that position during the procedures when other intravascular devices such guide wires and balloon catheters are being advanced through the inner lumen of the guiding catheter.
In the typical PTCA or stent delivery procedures, the balloon catheter with a guide wire disposed within an inner lumen of the balloon catheter is advanced within the inner lumen of the guiding catheter which has been appropriately positioned with its distal tip seated within the desired coronary ostium. The guide wire is first advanced out of the distal end of the guiding catheter into the patient's coronary artery until the distal end of the guide wire crosses a lesion to be dilated or an arterial location where a stent is to be deployed. A balloon catheter is advanced into the patient's coronary anatomy over the previously introduced guide wire until the balloon on the distal portion of the balloon catheter is properly positioned across the lesion. Once properly positioned, the balloon is inflated with inflation fluid one or more times to a predetermined size so that, in the case of the PTCA procedure, the stenosis is compressed against the arterial wall and the wall expanded to open up the vascular passageway. In the case of stent deployment, the balloon is inflated to plastically expand the stent within the stenotic region where it remains in the expanded condition. Generally, the inflated diameter of the balloon is approximately the same diameter as the native diameter of the body lumen being dilated so as to complete the dilatation or stent deployment but not overexpand the artery wall. After the balloon is finally deflated, blood flow resumes through the dilated artery and the dilatation catheter and the guide wire can be removed therefrom. Generally, the stent deployment may be accomplished simultaneously with or after a PTCA procedure has been performed at the stenotic site.
In addition to their use in PTCA and stent delivery procedures, guiding catheters are used to advance a variety of electrophysiology-type catheters and other therapeutic and diagnostic devices into the coronary arteries, the coronary sinus, the heart chambers, neurological and other intracorporeal locations for sensing, pacing, ablation, and other procedures. For example, one particularly attractive procedure for treating patients with congestive heart failure (CHF) involves introduction of a pacing lead into the patient's coronary sinus and advancing the lead through the patient's great coronary vein and a branch of the great coronary vein until the distal end of the pacing lead is disposed at a location which allows the electrical impulses from the pacing lead to pace the left ventricle of the patient's heart. A second pacing lead may be disposed within the patient's right ventricle or a cardiac vein draining the patient's right ventricle and both the left and right ventricle may then be paced by the pacing leads, resulting in greater pumping efficiencies and greater blood flow out of the heart which minimizes the effects of CHF.
Commercially available guiding catheters are typically constructed of a lubricious, polymeric inner liner, a polymeric outer jacket, and a reinforcing structure disposed between the inner liner and outer jacket formed of woven, braided, or wound strands which are usually metallic, high strength polymers or combinations thereof. The lubricious inner liner serves to diminish the frictional forces generated from the passage of interventional devices within the inner lumen. The lubricious inner liner is commonly formed of polytetrafluoroethylene (PTFE) because of its low coefficient of friction.
The conventional PTFE inner liner is relatively thin. Further reduction in its wall thickness is difficult, because the PTFE liner would lack the physical integrity to withstand the caustic chemical etching typically used to bond it to other catheter components.
On the other hand, clinical requirements for utilizing guiding catheters to advance catheters and other intravascular devices have resulted in a need for increased transverse dimensions of the inner lumens of guiding catheters to accommodate a greater variety of large intracorporeal devices with little or no increase in the outer transverse dimensions of the guiding catheter to present a low profile which facilitates advancement within the patient's body lumens and openings. These catheter design changes have required a reduction in total wall thickness, including a reduction in the thickness of the inner liner. It would thus be desirable to provide a thinner inner liner to maximize the inner lumen diameter. Alternatively, a reduction in the thickness of the inner liner would permit a reduction in the outer transverse dimensions of the catheter to ease passage through narrow, tortuous blood vessels or an increase in the thickness of the other catheter layers for greater strength without increasing the outer profile. A suitable thinner inner liner should still provide the requisite physical and mechanical properties for its use, such as lubricity, flexibility, and sufficient strength and integrity. In addition, it would be desirable if the inner liner material had physical characteristics which would not be compromised by radiation sterilization.
What has been needed is a catheter design incorporating a thinner inner liner with clinically-desirable characteristics. The present invention satisfies these and other needs.
The invention is generally directed to an intraluminal catheter, such as a guiding catheter, with a an inner liner including expanded Ultra High Molecular Weight Polyethylene (UHMWPE).
One embodiment of the present invention intraluminal catheter comprises an elongated shaft which includes expanded UHMWPE and has a proximal end, a distal end, and an inner lumen extending longitudinally therethrough. The expanded UHMWPE is microporous and has a node and fibril microstructure comprising nodes interconnected by fibrils. The expanded UHMWPE may be included in an inner liner defining the inner lumen of the elongated shaft. The expanded UHMWPE may also be included in an exterior lubricious coating on the elongated shaft.
In one embodiment, the inner liner including expanded UHMWPE has a thickness of about 0.0002 to about 0.0006 inch. In other embodiments, it has a thickness of less than about 0.0005 inch, and a thickness of about 0.00025 inch. In yet another embodiment, the inner liner including expanded UHMWPE has a porosity of about 20 to about 90 percent.
The elongated shaft may further include a polymeric outer jacket extending over the inner liner and a reinforcing structure disposed between the polymeric outer jacket and the inner liner. In one embodiment, the combined thickness of the inner liner, reinforcing structure and polymeric outer jacket is about 0.004 to about 0.005 inch. Optionally, the inner liner is impregnated with a polymer which is compatible with the polymeric outer jacket and is fusion bonded to the polymeric outer jacket. The impregnated polymer and polymeric outer jacket may be formed of PEBAX and fusion bonded together. Also, the inner liner may be secured to the polymeric outer jacket with a tie layer of a compatibilizing material.
In another embodiment, the invention comprises a guiding catheter having an elongated shaft having a proximal end, a distal end, an inner lumen extending longitudinally therethrough, and an inner liner defining the inner lumen which includes expanded UHMWPE and has a thickness of about 0.0002 to about 0.0006 inch.
In various embodiments, the present invention further provides methods for manufacturing an intraluminal catheter with an inner liner including expanded UHMWPE comprising bonding a tubular inner liner including expanded UHMWPE to a polymeric outer jacket extending over the inner liner. The inner liner is bonded to the polymeric outer jacket by impregnating the inner liner with a polymer which is compatible with the polymeric outer jacket and heat fusing the impregnated polymer in the inner liner to the polymeric outer jacket.
The present invention provides intraluminal catheters with improved characteristics due to the use of expanded UHMWPE as an inner liner. The inner liner formed of eUHMPWE is thinner than those currently employed because it is a stronger material which has sufficient integrity to be suitably bonded to other catheter components despite its thinness. This inner liner maximizes the diameter of the inner lumen relative to the outer profile of the catheter. The expanded UHMWPE inner liner also contains other desirable properties such as high lubricity, high flexibility, and resistance to flaking during abrasion. Further, expanded UHMWPE is radiation stable, unlike PTFE, permitting catheter sterilization by radiation, such as gamma rays or electron beams. Radiation sterilization improves the manufacturability of catheters as it can be quickly performed in the manufacturing line, while the ethylene oxide gas sterilization procedure, typically used with PTFE-lined catheters, requires storage for up to 48 hours to allow the gas to diffuse out of the sterilized equipment.
Furthermore, expanded UHMWPE has low processing temperatures, so it can be easily bonded to a variety of other polymeric catheter components. In contrast, PTFE has high processing temperatures not as suitable for many common polymeric materials used in catheters.
These and other advantages of the invention will become more apparent from the following detailed description of the invention and the accompanying exemplary drawings.
As shown in greater detail in
The inner liner 30 is a tubular member formed of expanded Ultra High Molecular Weight Polyethylene (i.e., expanded UHMWPE or eUHMWPE). The expanded UHMWPE inner tubular member may extend through the entire length of the shaft, although the non-traumatic distal tip 24 may be formed with a different polymeric material.
With regard to the material, the expanded UHMWPE in one embodiment is formed of basic UHMWPE, a polyethylene with a molecular weight typically between about 2 million and about 10 million grams/mole, that has been expanded or drawn to deform the UHMWPE into a microporous material exhibiting an oriented microstructure of nodes interconnected by fibrils. In this embodiment, the expanded UHMWPE may have a porosity of about 20% to about 90%. Examples of expanded, microporous UHMWPE having a node and fibril microstructure, and a suitably high orientation with an anisotropic structure or at least significant anisotropy in the structure arc described in PCT International Publication No. WO 91/01210 (Evans), incorporated by reference herein in its entirety. As described in WO 91/01210, such UHMWPE materials may exhibit a negative Poisson ratio.
The reinforcing structure 34 and polymeric outer jacket 32 may have a conventional construction. That is, the strands 36 that are woven, braided, or wound to form the reinforcing structure 34 may be formed of metal, high strength polymers, or a combination thereof. Suitable materials include stainless steel, nickel-titanium alloys, i.e., nitinol, aramid (Kevlar), nylon, or polyester (Dacron). The reinforcing structure 34 may be formed of a continuous structure throughout the elongated catheter shaft 12. In addition, the reinforcing structure 34 may extend through most of the length of the elongated catheter shaft except for the distal tip which is usually provided with a relatively flexible non-reinforced polymeric tubular member to provide non-traumatic characteristics to the distal tip.
The polymeric outer jacket 32 may be composed of various materials and compositions of varying stiffness. The polymeric outer jacket 32 of the proximal section 18 is preferably formed of a stiffer material than that of the distal section 20. Furthermore, the polymeric outer jacket 32 may be formed of a series of polymeric materials having distally decreasing stiffness. Employing variable stiffness along the length of the elongated shaft 12 provides the necessary stiffness for pushability as well as sufficient distal flexibility to permit maneuvering inside the patient's vasculature. The polymeric outer jacket 32 may be formed of a variety of thermoplastic and thermoelastic polymers, copolymers and blends. Suitable materials include polyamide, polyurethane, polyvinyl chloride, and polyethylene. In particular, the polymeric outer jacket 32 may be a polyamide elastomer, e.g., a polyether block amide such as PEBAX of various durometers alone or blended with nylon.
A process of forming the microporous node and fibril structure of the expanded UHMWPE generally entails compacting UHMWPE powder into a billet and then deforming the billet through a die and orienting the extrudate to impart the node and fibril structure. The step of compacting the polyethylene powder can be performed by any suitable means including applying pressure, with or without additional heat, or forming a slurry with a lubricating medium and then compacting the slurry into a billet. The lubricating medium is typically evaporated from the slurry after the extrusion of the billet through a die as is discussed below to impart the oriented node and fibril structure. For extrusion without a mineral oil lubricating medium, the polymer billet may optionally be sintered at temperatures exceeding the crystalline melting point of the polymer. After being compacted, the UHMWPE is then deformed to impart the oriented node and fibril structure. Typically, the UHMWPE is deformed by extrusion through a die followed by uniaxial or biaxial stretching of the extrudate. The deformation step may be performed either at ambient or elevated temperatures.
In one embodiment, sintered polyethylene is ram extruded at ambient temperature to form a sheet of material, which is then stretched, uniaxially or biaxially, to orient the structure. Optionally, the stretched material can be heat set. The processing of the UHMWPE also renders it microporous, and the amount of stretch experienced by the material controls the distance between the nodes and the corresponding fibril length.
The size and shape of the UHMWPE particles of the UHMWPE powder can be chosen to influence the node and fibril structure and optimize the properties of the resulting material. For example, the particle morphology determines the coarseness of the node and fibril structure and the ease of fibrillation during the deformation of the billet through a die. In one embodiment, the UHMWPE particles used to prepare the compacted polyethylene comprise an aggregate of primary particles. The aggregate has a diameter of about 100 μm to about 700 μm, and more particularly about 200 μm to about 400 μm, in size and is composed of aggregated or fused primary UHMWPE particles having a size of about 0.1 μm to about 40 μm, and preferably about 0.1 μm to about 20 μm. A suitable aggregate UHMWPE is grade GUR 2122, available from Ticona. Nonaggregated UHMWPE particles having a particle size of less than about 10 μm may be used to make the node and fibril structure materials, provided handling and safety problems associated with such fine particles are avoided.
The synthesis of UHMWPE is known to occur by Ziegler-Natta catalysis using a transition metal catalyst such as titanium, chromium or zirconium, and a cocatalyst such as aluminum. The nature of the catalyst and the order of the addition of the catalyst and co-catalyst affect the morphology of the resulting polymer. To synthesize material comprising an aggregate of a primary particle as discussed above, preferably a suspension polymerization of ethylene is used with a catalyst such as biscyclopentadienyl titanium dichloride, biscyclopentadienylzircomium dichloride, or cyclopentadienyl zirconium trichloride, and a co-catalyst such as trialkylaluminum, soluble in an alkane medium such as heptane or hexane. The trialklyaluminum co-catalysts include triethyl aluminum, tri-isopropylaluminum, and tributylaluminum. The synthesis of UHMWPE by Ziegler-Natta Catalysis is described in D. Breslow et al., J. Am. Chem. Soc., 31, 81-86 (1959), J. Chien et al., J. Polym. Sci. Polym. Chem., 31, 227-237 (1993), and U. Zucchini et al., J. Molec. Cat., 82, 45-56 (1993), incorporated in their entireties by reference herein. An open aggregate structure can be formed by the control of the polymerization rate, with use of a particular temperature and catalyst, which affects the particle stability and dynamics of aggregation.
As mentioned above, one method of, forming the UHMWPE generally comprises preparing a homogeneous paste of UHMWPE in a low boiling mineral oil. The paste is then compacted into a billet by applying pressure and optionally applying heat. The billet is then loaded into a ram extruder and a tube or film is extruded. The extrusion may be done at room temperature, or the temperature may be elevated. The oil is then evaporated from the UHMWPE by heating the film to a temperature not exceeding the crystalline melting point of the UHMWPE. The film or tube is then uniaxially or biaxially oriented to produce the oriented node and fibril structure. The oriented tube may then optionally be heat set at temperatures just above the melting point of UHMWPE, which has a crystalline melting point of about 130-140� C.
Another process comprises compacting UHMWPE particles into a billet at temperatures below the crystalline melting point of the polymer. Preferably, this step would be done at about 100� C. to about 120� C. The pressure applied is about 0.01 GPa to about 0.08 GPa, and in one embodiment about 0.01 GPa to about 0.1 GPa. The billet is then sintered at temperatures above the crystalline melting point of the polymer without applying any pressure. This step is completed at a temperature of about 130� C. to about 160� C. The sintered billet is extruded through a film or annular die in a ram extruder. The UHMWPE is then optionally oriented and heat set as described above.
The expanded UHMWPE material may be directly produced as a tubular member. Alternatively, the inner liner 30 can be formed from a film of the expanded UHMWPE. The expanded UHMWPE film is wrapped around a mandrel to form a tube and then heated to fuse the wrapped material together. The inner liner 30 can also be formed from a tape of the expanded UHMWPE which is wound around a mandrel and then heat fused to form a tube.
The resulting tubular member may be joined to the other catheter components. Typically, the woven, braided, or wound reinforcing structure 34 is formed around the outside of the tubular inner liner 30. The polymeric outer jacket 32 may then be provided on the exterior of the reinforcing structure 34 by suitable means, preferably by heat shrinking a polymeric layer of the desired composition onto the surface of the reinforcing structure 34. When applied, the outer jacket material flows through the spaces 38 in the woven, braided, or wound reinforcing structure 34 to bond to the inner liner 30. A removable mandrel may be used within the inner lumen 26 defined by the inner liner 30 during the manufacturing process to support and shape the catheter into its desired configuration while it is being formed.
The expanded UHMWPE inner liner 30 and polymeric outer jacket 32 may be secured together by any suitable method. In one embodiment, the inner liner 30 is impregnated with a polymer that is compatible with the outer jacket material. The polymer may be impregnated into the inner liner 30 by dissolving the polymer in a suitable solvent and applying the resulting solution to the inner liner 30 to allow it to impregnate the pores of the material. Optionally, the polymeric outer jacket 32 and the impregnating polymer are both formed of PEBAX. One common solvent for preparing a PEBAX solution is tetrahydrafuran (THF). The solution may be applied to the inner liner 30 by any of a number of ways, such as by injecting the resulting solution into the inner liner 30 by syringe or by brushing the solution on the outer surface of the inner liner 30. The solvent is then removed by evaporation at room temperature or by application of heat in an oven. The polymer in the solution remains mechanically locked within the porous structure of the inner liner 30. When the polymeric outer jacket 32 is applied be heat shrinking, it fuses to the compatible impregnated polymer in inner liner 30, thus securing the inner liner 30 and polymeric outer jacket 32 together.
In another embodiment, a tie layer of a compatiblizing material, such as PRIMACOR, is used to attach the expanded UHMWPE inner liner 30 with an incompatible material forming the polymeric outer jacket 32. The compatibilizing material may be applied to the outer surface of the inner liner 30 using conventional techniques. When the polymeric outer jacket 32 is applied to the catheter by heat shrinking, the compatibilizing material forms a fusion bond with the inner liner 30 and the polymeric outer jacket 34 to secure them together.
Optionally, expanded UHMWPE may be applied as a very thin, exterior lubricious coating 40 on guiding catheters or other intraluminal catheters, including electrophysiology catheters, angiography catheters, and angioplasty catheters, to ease passage through the patient's vasculature.
Guiding catheters designed for coronary artery access have varying lengths, generally between about 90 to about 130 cm, and more commonly the length is about 100 to about 120 cm. Catheters embodying features of the invention for providing access to the coronary arteries or cardiac veins through the coronary sinus have an inner diameter of about 0.06 to about 0.09 inch, and a wall thickness of about 0.004 to about 0.006 inch. In one exemplary embodiment, the wall thickness of the elongated catheter shaft 12 is about 0.004 to about 0.005 inch. The thickness of the inner liner 30 is about 0.0002 to about 0.006 inch. The thickness of inner liner 30 is less than 0.0005 inch, and in another embodiment, it is about 0.00025 inch. The guiding catheter has a generally constant inner and outer diameter throughout its length, and the wall thickness is also generally constant.
The present invention contemplates using expanded UHMWPE in conjunction with fillers, additives, or other polymers to produce inner liners or exterior coatings formed partially of expanded UHMWPE. The specific construction and chemical compositions of such fillers, additives, coatings, liners, and the like are known in the art.
It will be apparent from the foregoing that, while particular forms of the invention have been illustrated and described, various modifications can be made without departing from the spirit and scope of the invention. Moreover, those skilled in the art will recognize that features shown in one embodiment of the invention may be utilized in other embodiments of the invention. To the extent not otherwise described herein, the materials and methods of construction and the dimensions of conventional intravascular guide wires may be employed with the guiding member embodying features of the present invention. While the description of the invention is directed to embodiments for coronary applications, various modifications and improvements can be made to the invention without departing therefrom. Additionally, reference to the terms "members," "elements," "sections" and terms of similar import in the claims which follow shall not be interpreted to invoke the provisions of 35 U.S.C. �112 (paragraph 6) unless reference is expressly made to the term "means" followed by an intended function.
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|E.I. Du Pont De Nemours And Company
|Process of manufacturing ultrahigh molecular weight linear polyethylene shaped articles
|Alderson et al "Microstructural modelling of auxetic microporous Polymers" Journal of Material Science 30 p. 3319-3332 (1995).
|Alderson et al "Modelling concurrent deformation mechanisms in auxetic microporous polymers" Journal of Material Science 32 p. 2797-2809 (1997).
|Alderson et al "Strain-dependent behaviour of microporous polyethylene with a negative Poisson's ratio", Journal of Material Science 28 p. 4092-4098 (1993).
|Alderson et al "The effect of the processing parameters on the fabrication of auxetic polyethlene" Part II The effect of sintering temperature and time, Journal of Material Science 30 p. 4069-4075 (1995).
|Alderson et al "The interpretation of the strain-dependent Poisson's ratio in auxetic polyethylene", Journal of Strain Analysis vol. 32 No. 3 p. 201-212 (1997).
|Alderson et al. "Auxetic Polyethlene: the Effect of a Negative Poisson's Ratio on Hardness" Acta metall. Mater. vol. 42, No. 7 pp. 2261-2266 (1994).
|Caddock et al. "Microporous materials with negative Poisson's ratios: I. Microstructure and mechanical properties", Journal of Physics D: Applied Physics, 22(12): p. 1877-1882 (1989).
|D. Breslow et al., "Bis-(cyclopendtadienyl)-titanium Dichloride-Alkylaluminum Complexes as Soluble Catalysts for the Polymerization of Ethylene", J. Am. Chem. Soc., Jan. 5, 1959, p. 81-89, vol. 81.
|Evans et al "The static and dynamic moduli of auxetic microporous polyethlene", Journal of Material Science Letters 11 p. 1721-1724 (1992).
|Evans et al. "Microporous materials with negative Poisson's ratios: II. Mechanisms and interpretation", Journal of Physics D: Applied Physics 22 p. 1883-1887 (1989).
|Internet Web Site -http//www.devicelink.com/mpb/archive/98/03/003.html, Bajaria et al "Deformation, Morphology, and Wear Behavior of Polyethylene Used in Orthopedic Implants", (Medical Platics and Biomaterials Magazine MPB Article Index, 11 Pgs., visited Oct. 17, 2001-Originally published Mar. 1998.
|J. Chien et al., "Ethylene-Hexene Copolymerization by Heterogeneous and Homogeneous Ziegler-Natta Catalysts and the "Comonomer" Effect", J. Polym. Sci. Polym. Chem., 1993, p. 227-237, vol. 31.
|Neale et al "The effect of the processing parameters on the fabrication of auxetic polyethlene" Part III The effect of extrusion conditions, Journal of Material Science 30 p. 4087-4094 (1995).
|Pickles et al "The effect of the processing parameters on the fabrication of auxetic polyethlene" Part I The effect of compaction conditions, Journal of Material Science 30 p. 4059-4068 (1995).
|Pickles et al "The Effects of Powder Morphology on the Processing of Auxetic Polypropylene (PP of Negative Poisson's Ratio)" Polymer Engineering and Science, Mid-Mar. vol. 36, No. 5 p. 636-642 (1996).
|U. Zucchini et al., "Behaviour of [Ti2(OEt)8Cl]2Mg2(mu-Cl)2 as catalyst component in the Ziegler-Natta polymerization of alpha-olefins and diolefins", J. Molec. Cat., 1993, p. 45-56, vol. 82.
|U.S. Appl. No. 09/713,642, filed Nov. 14, 2000, "Medical Device Formed of Ultrahigh Molecular Weight Polyolefin".
|Citing Patent
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|Abbott Cardivascular Systems, Inc.
|Robust catheter tubing
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|AUST Development, LLC
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|Robust multi-layer balloon
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|Abbott Cardiovascular Systems, Inc.
|Catheter having transitioning shaft segments
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|Stephen A. Leeflang
|Strip lined catheters and methods for constructing and processing strip lined catheters
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|Abbott Cardiovascular Systems Inc.
|Catheter with a dual lumen monolithic shaft
|25 Feb 2013
|13 May 2014
|Abbott Cardiovascular Systems Inc.
|Balloon catheter shaft having high strength and flexibility
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|24 Jun 2014
|AUST Development, LLC
|Apparatus and methods for making coated liners and tubular devices including such liners
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|6 Jan 2015
|AUST Development, LLC
|Apparatus and methods for making coated liners and tubular devices including such liners
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|Delivery of medical devices
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|Abbott Cardiovascular Systems Inc.
|Balloon catheter tapered shaft having high strength and flexibility and method of making same
|9 May 2003
|11 Nov 2004
|Poole Matthew S.
|Catheter having selectively varied lamination
|9 May 2003
|11 Nov 2004
|John Horrigan
|Laminated catheter comprising ultra high molecular weight high density polyethylene
|2 Jun 2004
|20 Jan 2005
|Terumo Kabushiki Kaisha
|Catheter assembly
|26 Jan 2006
|5 Apr 2007
|Leeflang Stephen A
|Catheters with lubricious linings and methods for making and using them
|26 Jan 2006
|5 Apr 2007
|Leeflang Stephen A
|Catheters with lubricious linings and methods for making and using them
|26 Jan 2006
|19 Apr 2007
|Leeflang Stephen A
|Catheters with lubricious linings and methods for making and using them
|4 Jul 2011
|11 Jan 2012
|Aust Development, LLC
|Serial valves and hubs for tubular devices and methods for making and using them
|2 Mar 2007
|13 Sep 2007
|Advanced Cardiovascular System
|Catheter shaft with a lubricious surface
|30 Jan 2014
|7 Aug 2014
|W.L. Gore & Associates, Inc.
|Method for producing porous articles from ultra high molecular weight polyethylene
|U.S. Classification
|606/108, 606/194, 606/192
|International Classification
|Cooperative Classification
|European Classification
|26 Dec 2001
Owner name: ADVANCED CARDIOVASCULAR SYSTEMS, INC., CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:CHLUDZINSKI, MATT;HAMMILL, ERIC;REEL/FRAME:012421/0473;SIGNING DATES FROM 20011219 TO 20011220
|19 Jun 2008
|Fee payment
Year of fee payment: 4
|25 Jun 2012
|Fee payment
Year of fee payment: 8


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text: Date rape drugs are pretty much impossible to detect, since they don't change the taste or smell or look of a drink. After Michael Abramson was roofied himself three years ago—maybe accidentally, or maybe as the target of an intended robbery—he decided to find a solution to warn people. His new cups and straws are designed to change color if a drug like GHB is present, and will start shipping to Indiegogo backers next month.


text:
The Doing Business survey published by the World Bank and International Finance Corporation, covering 185 countries showed that over the past year Estonia, ranking 24th , has fallen 7 places in the list of the world's most business friendly countries, writes Anne Veerpalu, senior associate of Law Firm GLIMSTEDT.
The Doing Business survey primarily assesses the legal environment relating to business (incl. setting up a business, construction licenses, protection of property and investments, contract enforcement, closing down) and based on that makes a list of the countries that are the most friendly as business environment. A country will get a minus for every individual contact with an authority that an entrepreneur must make when setting up and running a business.
The survey is based on the assumption that a business environment needs regulation that is prepared "wisely", well thought through, transparent and accessible to everyone, effective and with balanced interests, i.e. that the need to protect consumers will not incur irrational expenses on the entrepreneur. The overview of developments in the regulatory policy in 2011, compiled by the Estonian Ministry of Justice, shows that Estonia's position in the Doing Business list is critical to defining the regulatory policy trends of Estonia.
However, an overview of the regulatory quality, compiled by the National Audit Office at the end of the last year, shows that practically no assessment whatsoever has been made on the effects of regulations on the business environment. Thus, in reality the effects of regulation on business environment have not been clearly mapped or reasoned. Minister of Justice, Kristen Michal, is hoping that the code of practice for good regulation, approved by the Government at the end of the last year, will remedy this situation.
Therefore, those responsible for the regulatory policy have realized that entrepreneurs play an important role in making the business environment more attractive – by generating markets, creating competition, investing in R&D, constructing ports, roads and infrastructures.
Business cannot grow to its full potential in Estonia not only because of a lack of resources, skills or the will, but also because it finds a more fertile environment to grow elsewhere – for example, in one of those 23 countries ranking ahead of Estonia in the "friendliness" list.
In his New Year's wish Estonian venture capitalist Allan Martinson in an extremely positive and optimistic tone called on the entire population of Estonia to start a business during the current year. As stated in the Estonia business daily Äripäev (January 4th, 2012, Editorial) the condition for success as an entrepreneur in Estonia are not bad at all: "After all, Estonia meets all the main preconditions. Setting up a business takes less than a minute. Our business environment is simple. Our information technology infrastructures are advanced. Our taxes are low compared to our neighbors."
So what is still missing? All of you who have already granted Martinson's wishes beforehand and are engaged or in some other way participate in business know the answer.Thus, I am calling on you to have a say and let us know what is it that makes the life of an entrepreneur (an existing and a future one) hell.
• How could Estonia become more business friendly and rise in the Doing Business list instead of falling?• Have you though of what is inhibiting the freedom of your business to reach its full potential?• Is it a national requirement or limit or a municipal restriction that is too demanding? Are those restrictions rational and proportional?• Could the regulation be changed to better support your business?• How could Estonia be transferred from a "good" regulatory policy development trend to a "wise" regulatory policy development trend?
GLIMSTEDT's in Business Transaction team welcomes your suggestions and opinions about what to do in order to make Estonia one of the world's most business friendly countries. Please send you opinion and thoughts to firstname.lastname@example.com
Äripäev writes that Estonian tax authority plans to zoom on all businessmen who are saving on labour costs by using private liability companies. COMMENTS (1)
Äripäev writes that two taxi companies Tallink Takso and Tulika are urging their drivers to stop using Taxify tax booking app and have launched their own joint app called Taxofon.
Äripäev writes that TransferWise co-founders Taavet Hinrikus and Kristo Käärmann have been named Ernst and Young UK Entrepreneurs of the Year 2015.
In August 394,000 tourists stayed in Estonian accommodation establishments, up 4 percent in a year, Statistics Estonia reports.
Postimees writes that business magazine Forbes Eesti is owing salary to several staff members.
Äripäev writes that Olympia Baltic Opportunities Fund, a French investment company that recently acquired the main building of the Police and Border Guard Authority wants to own six buildings by the year-end for up to 200 million eurosCOMMENTS (1)
Äripäev writes that the new law on credit providers and brokers that will enter into force next March could end the business of many companies that are providing instalment payments.
Estonian business lacks of business ethics and integrity, especially if one compares it to Finland, says Toomas Peek, an Estonian telecom businessman and investor.
Estonia's new Enterprise Minister Liisa Oviir (SDE) says in Äripäev that the state must reduce bureaucracy and interfere in the economy only if it is vitally important.
Postimees writes that a security check by software giant Google has showed that about 250,000 electronic ID cards issued in Estonia including more than 5,000 electronic identity cards issued by Estonia to e-residents are faulty as their certificate does not conform to standard.COMMENTS (3)
Shady Russian banker Mikhail Nadel was applying for Estonian citizenship a few years ago and attempted to start a business in Estonia.
The Harju county court ruled today that Tallinn Mayor Edgar Savisaar should be removed from office for the preliminary investigation of a corruption case.COMMENTS (1)
The fresh list of richest Estonians published by the business daily Aripaev on Tuesday shows Kristo Kaarmann, one of the founders of Transferwise, as the wealthiest person here with an estimated net worth of 234 million euros.
In October 2014, the gross hourly earnings of female employees were 23.3% lower than the gross hourly earnings of male employees. COMMENTS (4)
Äripäev writes that shared services centres that foreign multinationals have set up in Estonia in recent years are notably successful.COMMENTS (1)
Most businessmen agree that such corruption cases as the latest one surrounding Mayor of Tallinn Edgar Savisaar show Estonia's business climate from a bad angle.COMMENTS (2)
The Internal Security Service KAPO on Tuesday detained Tallinn Mayor Edgar Savisaar as a suspect for repeatedly accepting bribes.COMMENTS (1)
Today morning KAPO detained Edgar Savisaar, mayor of Tallinn and chairman of Center Party.
Äripäev writes that Estonian entrerepeneurs are facing tougher times as the economy is growing at a snail's pace and expectations are low also for the next year.
Owners of Infortar which controls the listed Tallink ferry group are still interested in investing in Estonian Air.
The state plans to set up a new national airline in the event that the European Commission rules that Estonian Air has received illegal state aid that must be repaid, reported Aktuaalne Kaamera.
Estonian tax board is struggling with a new tax evasion scheme where companies buy homes which are then used either as the home for the company's owner or are rented out.COMMENTS (2)
Estonian farming organisations are today holding a protest rally outside Toompea Castle, reports Eesti Päevaleht.
Tallinn Airport estimates that 2.2 million people will travel through the airport in 2015, almost 10 percent more than last year.
Siim Roode, a lawyer who has been charged in the Autorollo criminal case, is involved also in another prominent bankruptcy case around Catmet Ltd.
According to Statistics Estonia, in July 2015, exports of goods decreased by 6% year on year.
Statistics Estonia reported today that 458,800 tourists stayed a night in Estonia in July, which is 4% more than in July 2014. COMMENTS (1)


text:
The 64th Annual Meeting of the American Physical Society's (APS) Division of Fluid Dynamics (DFD) will include more than 2,000 compelling presentations from across the physical sciences, engineering, and medicine. Topics include: explosions -- from tiny experiments to massive stars; the quirks of flying; why coffee spills; and how rain contributes to the spread of disease among plants.
The meeting will take place November 20-22, 2011, at the Baltimore Convention Center in the historic waterfront district of Baltimore, Maryland. Reporters are invited to attend the conference free of charge. Registration instructions and other information may be found at the end of this news release.
Preliminary Meeting Highlights
Fluid Dynamics of Bottle Filling: From large bottles with shampoos and cleaners to small bottles found in the pharmaceutical industry, the filling of bottles is a widely practiced operation in a large number of industries. Researchers will present a primarily computational study of the fluid dynamical challenges that can arise during the rapid filling of bottles.
How Mosquitoes Fly in the Rain: Raindrops are 50 times heavier than mosquitoes, yet the pesky insects still manage to thrive during rainfall and high humidity. High-speed video reveals that even a bull's-eye raindrop hit simply pushes past, letting mosquitoes buzz along to find their next meal.
From a Slow Burn to Supersonic Detonation: The transition from deflagration a subsonic flame to a supersonic detonation can occur in environments ranging from experimental and industrial systems on Earth to astrophysical thermonuclear supernovae explosions.
|Contact: Charles E. BLue
American Institute of Physics


text:
Latest: Quest Diagnostics Introduces Dako's PD-L1 Companion Diagnostic for KEYTRUDA®
Latest: EKF's Unique and Simple Creamatocrit Analyzer Highlighted at FIGO
Latest: 10 Traits of a Science Lab Superhero
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What Not to Miss at ASHG 2015
Targeting Genetic Disease in Saudi Arabia
Quest Diagnostics Introduces Dako's PD-L1 Companion Diagnostic for KEYTRUDA®
System Isolates More than 10,000 Single Cells per Day and Automatically Selects Cells to Process
10 Traits of a Science Lab Superhero
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Evaluation of the Effect of Red Chilli Addition to Food Products on Their Shelf-Life
amaZon speed ETD: Optimization of CID Parameters for Improved Glycopeptide Fragmentation
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Multi-Residue Pesticide Analysis in Onion by a Modified QuEChERS Extraction and Ion Trap ...
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The knowledge of the chemical composition of aerosols is of great importance due to their potential adverse effects on the environment and human health. Due to the small size of typical aerosol particles, the challenge is physicochemical characterization of aerosols at the micron scale. This application note explores the use of confocal Raman microspectrometry for the characterization of aerosol particles and other applications.
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XploRA - Raman microscopy
LabRAM HTS - Raman Micro/Macro Screenin...


text:
My husband and I had a wonderful 5 nights in Daniele and Alain's very comfortable apartment. It was like a home away from home in a lovely and convenient neighborhood of Neuchatel. Daniele and Alain go out of their way to welcome their guests. We particularly enjoyed our breakfasts, delicious food in their beautiful dining room.
Top-rated Attractions Nearby
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text:
Bridges Fall Symposium
Bridges Success Stories
Cal Poly Student Luz Gomez
Bridges to the Baccalaureate opened a world of opportunities. As a Biology Major, I gained hands-on experience in biology and mechanical engineering. I met and worked with world-renowned professors at Cal Poly. They helped me feel comfortable and capable of working in a university setting which prepared me for a smooth transfer. It is very rare for an undergraduate student to work in a lab and get paid for it. I still hold those positions and I couldn't have excelled without support from Bridges. I am very fortunate to have been part of the program. Thank you Bridges!
Join the AHC Bridges to Baccalaureate Group on Facebook!
Ruben Reyna
Culinology® student
"Allan Hancock College has helped me acquire the skills that I need so I can transfer to another college and complete my education as a chef and minor in business. With my education I plan to open and manage my own establishment."
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text:
- 351Promote
Canvas Print
new york inkedby Bri.buckley
Fine art print on bright white, fine poly-cotton blend, matte canvas using latest generation Epson archival inks. Individually trimmed and hand stretched museum wrap over 1-1/2" deep wood stretcher bars. Includes wall hanging hardware.
colorful watercolor new york city skyline print
new york,new york city,new york skyline,skylines...
Very nice..............>
Good stuff
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love it
Nice colours!
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Thanks garyharr
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thanks texnotropio
very cool!
I just came back from NYC after almost a decade away. This seems to carry the same kind of vibrance of roaming through Midtown, Hells Kitchen, UES and Brooklyn...feel right.
thanks pom
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This is great!! wonderful work!
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Love your style!!!
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great energy and color!
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Un disegno con tutta l'energia di NY!
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Wild technique for a wild city, great stuff!
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GREAT Piece!
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Like your expressive art !
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cheers louisa
This is great, really love the colour palette.
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text: My flowers were beautiful! The centerpieces and bridal party flowers were exactly what I asked for and matched the pictures I sent perfectly. My bouquet was a lot bigger than I thought they were going to be but I loved them. Everyone raved about how gorgeous the flowers were and I was so happy with the final outcome. The girls at the shop are super nice as well


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This was my first attempt at a persistent (disk-based) allocator, but I aimed too high, used too many obscure C++ features and it got away from me. You will need the version of v3c mentioned in configure.ac.in to build it. Like I said, it contains lots of really obscure C++, if you're curious. This project isn't being actively maintained anymore - see it's way-cooler C/C++ replacement here at SourceForge - treedb.2 weekly downloads
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A one file PHP 5.2.x web development framework built on the o.php libraries and using the JSON Template engine. The complete system weighs in at 50KB and gives you the tools to make simple sites quickly.1 weekly downloads
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Geek is trying to provide a framework to help developer use tcl/tk to write and deploy pragram. It can wrap a tcl/tk program to .EXE in windows platform, compile tcl/tk code to TCL ByteCode and the package management is much like java class/jar.1 weekly downloads
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text:
Publications Mathématiques de l'Institut des Hautes Études Scientifiques
, Volume 96, Issue 1, pp 199-275
First online:
Stability and instability for Gevrey quasi-convex near-integrable Hamiltonian systems
- Jean-Pierre MarcoAffiliated withUniversité Paris VI, UMR 7586, Analyse algébrique, 4 place Jussieu, 75252 Paris cedex 05, France, email@example.com
- , David SauzinAffiliated withCNRS – IMCCE, UMR 8028, Astronomie et systèmes dynamiques, 77 av. Denfert-Rochereau, 75014 Paris, France, firstname.lastname@example.com
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Abstract. – We prove a theorem about the stability of action variables for Gevrey quasi-convex near-integrable Hamiltonian systems and construct in that context a system with an unstable orbit whose mean speed of drift allows us to check the optimality of the stability theorem.¶Our stability result generalizes those by Lochak-Neishtadt and Pöschel, which give precise exponents of stability in the Nekhoroshev Theorem for the quasi-convex case, to the situation in which the Hamiltonian function is only assumed to belong to some Gevrey class instead of being real-analytic. For n degrees of freedom and Gevrey-α Hamiltonians, α ≥ 1, we prove that one can choose a = 1/2nα as an exponent for the time of stability and b = 1/2n as an exponent for the radius of confinement of the action variables, with refinements for the orbits which start close to a resonant surface (we thus recover the result for the real-analytic case by setting α = 1).¶On the other hand, for α > 1, the existence of compact-supported Gevrey functions allows us to exhibit for each n ≥ 3 a sequence of Hamiltonian systems with wandering points, whose limit is a quasi-convex integrable system, and where the speed of drift is characterized by the exponent 1/2(n−2)α. This exponent is optimal for the kind of wandering points we consider, inasmuch as the initial condition is located close to a doubly-resonant surface and the stability result holds with precisely that exponent for such an initial condition. We also discuss the relationship between our example of instability, which relies on a specific construction of a perturbation of a discrete integrable system, and Arnold's mechanism of instability, whose main features (partially hyperbolic tori, heteroclinic connections) are indeed present in our system.
- Title
- Stability and instability for Gevrey quasi-convex near-integrable Hamiltonian systems
- Journal
Publications Mathématiques de l'Institut des Hautes Études Scientifiques
Volume 96, Issue 1 , pp 199-275
- Cover Date
- 2003-05
- 10.1007/s10240-003-0011-5
- Print ISSN
- 0073-8301
- Online ISSN
- 1618-1913
- Publisher
- Springer-Verlag
- Additional Links
- Authors
- Jean-Pierre Marco (A1)
- David Sauzin (A2)
- Author Affiliations
- A1. Université Paris VI, UMR 7586, Analyse algébrique, 4 place Jussieu, 75252 Paris cedex 05, France, firstname.lastname@example.com, FR
- A2. CNRS – IMCCE, UMR 8028, Astronomie et systèmes dynamiques, 77 av. Denfert-Rochereau, 75014 Paris, France, firstname.lastname@example.com, FR


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With just over a month until ballots are mailed to Denver voters, candidate Carol Boigon [1] is the first in the field of 10 running for mayor to release a television commercial.
"It's an introduction," said Boigon's spokeswoman, C.L. Harmer. "It certainly gives the campaign a boost."
The 30-second ad, produced by the East Coast-based SKDKnickerbocker communications company, will begin airing Tuesday. It is a nod to a 2005 commercial featuring former Denver Mayor John Hickenlooper [2], who was campaigning for the passage of state Referenda C & D by jumping out of a plane.
"Mayor Hickenlooper went to great heights for this city," Boigon says, sitting in an airplane strapped to a parachute.
The at-large councilwoman says she'll "combine new, good ideas to create high tech jobs and grow the economy, with a healthy dose of Denver values that say we can create good jobs while caring for our seniors and our kids."
But Boigon doesn't jump. She steps out of the parked plane sitting on a runway, saying: "So – while you won't catch me jumping from planes…I'll do what it takes to make Denver soar."


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We have two miniature schnauzer puppy's that will be ready 10/16/15 They are up to date on shots wormed regularly. Will be vet checked before they leave and come with health certificate from our vet. Puppy's are started on house braking. Our puppy's are raised in our home and handled daily. Both parents are on premises. Both parents are AKC and ACA reg. Puppy's come with no papers.
Oct 9 -
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We have 1 F left, we have pictures and more information on our website or email, call or tex. Puppy is sold on a 1st come 1st served basis puppy will not be held. Puppy is $650 (pet AKC registration) $800 (Breeding AKC registration). Cash only (absolutely no checks or money orders) no shipping, puppies come dewormed and with current vaccine for their age as well as a puppy kit and food sample ...
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Looking for quality proven male, as my boys are too old .Prefer around 9-12 lbs s& P or white however will consider others.or little more weight .
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New York - Dogs & puppies
I have 2 little girls in this litter, both are salt and pepper. They are out of Toby x Ester. They will be ready to go 8/20/15. I expect these little girls to get approx. 16 lbs. For more information about me and my dogs please go to www.rockycreekkennel.net. First two pictures are red collar and second two are purple collar.
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Gorgeous designer Miniature Schnaussie puppies. Miniature Australian Shepherd x Miniature Chocolate Schnauzer. Recognized by the Designer Breed Registry and the International Designer Canine Registry. Born August 3, 3015. Ready to go September 28th. All have wonderful temperaments and will make great family pets. Two females and 1 male. Black male with with markings $500, black female ...
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Purebred Toy & Small Miniature Schnauzer Puppies – We currently have a liver pepper & tan male puppy that will be ready to go to his new home on October 19. Please visit us online at www.taylorstoyschnauzers.com. We raise salt & pepper, black, white, liver, liver pepper, white chocolate, wheaten and parti schnauzer puppies in a slightly smaller package. These puppies are family raised in a ...
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Hi I have some cute little guys who want some love! Working on create training and go outside often. They are happy go lucky and love to play. Will be 12-18 lbs fully grown. They have more poodle look then schnauzer at this time. Please email for current pictures
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Very sweet fun energetic young girl. She is looking for a interactive home. Raised with kids and other animals.
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We have Ma-Duce & K-Bar their litter is ready for new homes immediately. we have 1 F left, we have pictures and more information on our website http://www.vonteufulhundenkennels.com/current-litters.html. All puppys are sold on a 1st come 1st served basis no puppy will be held. Puppies are sold for $650 (pet AKC registration) $800 (Breeding AKC registration). Cash only (absolutely no checks or ...
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Now taking reservations for a litter sired by our Razor (pictured) and our salt & pepper female, litter due Oct. 2015. Pups will ready Dec. 2015, pups will have shots, wormed, tails docked, dewclaws removed and ears natural. $975. 732-840-0739 Please calls only, not text/email enabled. Thank you, Jackie
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I have 2 females and 1 male I'm looking to rehome. Prices range from 100.00 and up. All are AKC registered, male is AKC and CKC registered. All are UTD on shots and have been kept and raised inside. Females must be spayed upon purchase. May consider selling male with breeding rights. All must go to home where they will be kept inside as part of the family. Black and White parti female is 7 ...
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This ad was posted with the eBay Classifieds mobile app.
Aug 30 -
Central New York :
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AKC reg miniature schnauzer puppies for sale. We have two males and 2 females available and all are black. Puppies are raised in our home and handled daily by adults and children. Puppies have begun potty training and will come with first shots,wormer and lifetime health guarantee.
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Four mini schnauzer for sale. Both parents on premises. 2 white female.1 salt and pepper male.1 black and gray female. First shots and tails have been docked. $100 will hold puppy of your choice, which will be deducted from the final price. Puppies can be CKC registered.Born June 17.
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In June I took in my dog Lady from a relative who could no longer care for her. Shortly after I discovered she was pregnant! Now she has a beautiful litter of 7 Morkies! 6 of them still need homes(black pup already sold). They are currently being potty trained and weaned off of breast milk.
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text: Book Review: Island No. 10: Struggle for the Mississippi Valley (Larry J. Daniel and Lynn N. Bock) : ACW HistoryNet Staff 8/11/2001 Island No. 10: Struggle for the Mississippi Valley, by Larry J. Daniel and Lynn N. Bock, University of Alabama Press, Tuscaloosa, $24.95.Because it was sandwiched between the major battles of Fort Donelson and Shiloh, historians have relegated the action at Island No. 10 to footnote status. In Island No. 10: Struggle for the Mississippi Valley, Larry J. Daniel and Lynn N. Bock have addressed that oversight with the first book-length treatment of a fascinating part of the American Civil War.Located on a fortuitous bend of the Mississippi River near New Madrid, Mo., Island No. 10 was one of the strongest natural positions available to stop the advance of Union forces in the Western theater. In August 1861, Confederate Brig. Gen. Gideon Pillow sent troops to the area to begin work on a series of redans, batteries and other fortifications. Ultimately, the island and the adjacent Tennessee shore would support more than 40 pieces of heavy artillery, including several 8-inch Columbiads and a massive 128-pounder rifle. The arrival of the floating battery New Orleans brought the total to 52 guns.In late February 1862, Union Brig. Gen. John Pope began massing his troops at Commerce, Mo., for an overland strike at New Madrid. To counter the threat, Confederate Brig. Gen. A.P. Stewart relied on the forts at New Madrid. With supporting fire from Confederate gunboats, Stewart resisted Pope's advance for a week and a half. The arrival of siege guns, however, gave Pope the upper hand. Stewart evacuated the town during the night of March 13, and Pope was rewarded with a swift promotion to major general.Confederate shore batteries prevented Union forces from crossing the river to invest Island No. 10. The stage was now set for the first substantial siege of the war. While Confederate Brig. Gens. John P. McCown and William W. Mackall stubbornly held their ground, Union flag officer Andrew H. Foote used his ironclad gunboats and mortar boats to bombard the Confederate fortifications. Colonel J.W. Bissell's engineers cut a canal across the flooded lowlands so that Union transports could bypass the island.After three weeks of stalemate, Captain Henry Walke volunteered to take his ironclad, Carondelet, on a daring nighttime run past the formidable guns of the island. Walke was successful, and the gunboat soon knocked out the downstream Confederate batteries and allowed Pope's troops to cross in transports. Surrounded, Mackall was forced to surrender on April 8. More than 4,400 prisoners were taken, but it was the large loss of heavy guns that would prove most damaging to the Confederacy.Daniel and Bock provide a thoughtful analysis of the brilliant maneuvers and fatal mistakes of the campaign. The narrative is enhanced with maps, illustrations, notes and a comprehensive bibliography. Island No. 10 will become the standard reference for this forgotten facet of the war.Mark Chance Leave a Reply Cancel Reply Your email address will not be published. Name* Email* Website Comment


text: Location is pretty cool right on the fast flowing river Napo, although the nearby town of Tena which we drove through wasn't! Staff are very nice and friendly and manager Leonardo speaks very good English. Bungalow was basic though the view of the river is beautiful. No electricity apart from the reception / bar and dining area - slight drawback... More


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text:
England v New Zealand: Joe Root hits maiden Test hundred
Second Test, Headingley (day two, close):
England 337-7 v New Zealand
Joe Root thrilled his home crowd with his maiden Test century to put England in a solid position against New Zealand at Headingley.
The 22-year-old, playing only his sixth Test, put on 124 for the fifth wicket with his Yorkshire team-mate Jonny Bairstow.
Root became the first Yorkshireman to score his maiden Test century at Headingley and the 11th youngest England centurion of all time before falling to the first delivery with the new ball for 104.
Bairstow soon followed after a fluent 64 and Stuart Broad made a duck as England threatened to undo much of their good work before Matt Prior's quick-fire unbeaten 38 took them to 337-7 at the close on day two.
Test Match Special analysis
"Joe Root's played beautifully, but ever since he was about 15, we at Yorkshire felt we had a good player here and that he had what it takes to be pretty special. He has good touch, good footwork, plays the ball late, and it always helps to play at your home ground as you're used to the pace."
The hosts, who lead the two-match series 1-0 following a 170-win in the opening Test at Lord's, will be looking to push on towards 400 on Sunday before picking apart the Kiwis' fragile batting line-up.
England had lunched on 67-3, with Jonathan Trott and captain Alastair Cook falling in successive balls before the interval after Nick Compton had gone early for just one.
Ian Bell added 30 in a partnership of 79 with Root, but it was the combination of the young Yorkshire pair that really transformed the mood among the colourful Headingley crowd.
Scoring heavily square of the wicket on both sides, Root reached his fifty off 90 balls and accelerated into the nineties after tea.
Then came two heart-stopping moments.
On 92, a Bairstow drive deflected off bowler Neil Wagner and on to the stumps at the non-striker's end, but fortunately Root had not strayed far from his crease and grounded his bat in time.
Shortly afterwards, he survived an appeal for a catch down the leg side, with New Zealand using up a review to establish that the ball merely brushed Root's pads.
To his credit, Root retained his composure and advanced from 94 to his hundred in the space of two balls, punching the air in celebration as the crowd rose to its feet to toast the local hero.
New Zealand needed a spark and they found one in Trent Boult with the new ball in his hands.
Joe Root's first-class scores this season
- 49 & 182 - Yorkshire v Durham, Championship, Headingley
- 236 - Yorkshire v Derbyshire, Championship, Headingley
- 179 - England Lions v New Zealand, tour match, Leicester
- 40 & 71 - England v New Zealand, 1st Test, Lord's
- 104 - England v New Zealand, 2nd Test, Headingley
Root, perhaps switching off momentarily after reaching three figures, chased a length ball and nicked to the keeper.
Bairstow, who struck eight fours in an innings which mixed timing and power, mis-judged an attempted leave and toe-ended a catch behind.
A Broad inside edge from the first ball of Boult's next over gave McCullum - keeping wicket in the absence of the injured BJ Watling - his fifth catch.
The momentum almost shifted further in New Zealand's favour, but Doug Bracewell put down a tough chance at midwicket to remove Prior for 21 and the England wicketkeeper, in tandem with Graeme Swann, ensured the hosts finished the day in the ascendency.
After rain washed out Friday's first day, Headingley was bathed in sunshine on Saturday morning as cricket fans - many in fancy dress - streamed in through the gates.
England won the toss and chose to bat but were swiftly one down as Compton followed an away-swinger from Tim Southee and was caught by the agile Dean Brownlie at third slip.
After back to back centuries in New Zealand, Compton has scored 45 runs in his last five Test innings.
Cook and Trott looked to be bedding in for a long partnership only for England's steady progress towards lunch to be checked by a double-strike.
Trott drove expansively at a tempting ball outside off stump from Wagner and was caught behind and, from the first ball of the next over, Cook's lack of footwork proved his undoing as he nicked to third slip.
Bell successfully reviewed an lbw appeal on 12 but succumbed meekly for 30 when he feathered part-time spinner Kane Williamson through to the keeper.
At 146-4, England needed a partnership of substance, which Root and Bairstow duly delivered to the delight of their adoring public.
Comment number 27. Posted by Stevon 25 May 2013 19:34
@ 23 Go back to your village son, they need their idiot back.
Comment number 32. Posted by Margy Nalgainon 25 May 2013 19:43
What a lovely picture at the head of this report! The old mantra: A strong Yorkshire; a strong England. People mock Yorkshiremen but you'll never know how proud we feel! To the naysayers, you'll never know what it means to be born in the county.
Parochial? Me? Yes. What of it?
Comment number 22. Posted by BBCSportwebsiteaddicton 25 May 2013 19:21
Good to see the lad perform, must have taken confidence from getting back to his roots at Headingly.
Comment number 45. Posted by Grimli01on 25 May 2013 20:12
@41 they were supposed to make up time for yesterday.
An hours extra play and they only made up 4 overs.
Kmt correct!
Comment number 46. Posted by rpbon 25 May 2013 20:15
41 - what planet are you on. They had 7 hours play today. That 13.5 per hour. Not the required 15.
Comment number 44. Posted by kmton 25 May 2013 20:12
@41 New flash!! yeah with an extra hour's play!! At normal close of play they were under the required rate as they were at Lords where they were fined. And I'm afraid as many sides are these days - monetary fines don't work - perhaps runs would.
Comment number 79. Posted by matthueycamoon 25 May 2013 23:19
77. Mort . I suppose even sobers had his detractors.
1) Cook
2) Trott
3) Root
5) Bell
6) Prior
7) Bairstow/Bresnan/Panesar/Craig Kieswetter depending on the situation.
8) Broad
9) Swann
10) Finn
11) Anderson
Comment number 84. Posted by Kurt Repleion 25 May 2013 23:45
back in 2005 Ian Bell had a torrid Ashes series, but the selectors stuck with him. A test average now of 46.7 shows why, one of the best.
Mort, you are a fool to judge a player's career on his start.
And Root does look good.
Comment number 81. Posted by Tony Fisheron 25 May 2013 23:32
I had doubts last year about Joe Root because I thought he was dull, but no more; he's the real deal. And Jonny Bairstow's come a long way from when he was playing junior cricket against my son; we seem to be forgetting that he's also an excellent keeper and natural successsor to Matt Prior. These two deserve to be playing test cricket for a long time.
Comment number 75. Posted by GumboGoobleon 25 May 2013 22:56
For 'Mort' read 'Papa Shango'
For 'Bell' read 'Collingwood'
Some of you out there will get this!
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