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CRM Software
Apache Cocoon applications available are 1. a small shop 2. a drill-down directory 3. Helpdesk 4.DynaShop. Visit http://beaverdesk.sourceforge.net/6 weekly downloads
Dyonisos 4 SugarCRM
Dyonosos is a .NET client for SugarCRM. Its features off line capabilities, •Multithreaded, UMPC User interface. Target are sales and service people that are on the road not always connected.0 weekly downloads


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A new classic Chloe style that you will be able to fit all daytime essentials in with ease. Shown here with Chloe boots, skirt, cardigan and blouse.
Black patent leather tote with inside out straps, a zip fastening across topand gold hardware. Bag has a magnetic fastening small pouch pocket on the front with a larger pouch on top, large gold rectangular trim and studded belted detailing on both sides. Bag also has a zip fastening internal pocket and a smaller open pouch internal pocket.
Product code: 25552 - Need help? Contact us


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Renewal Center is a Catholic non-profit ministry offering
a full schedule of opportunities for faith formation, spiritual
renewal,and ministry development.
Faith Enriching Programs
Come and Discover What "More" God Has for
is Spiritual Direction? Is it for You?
- Thursday, September 10th, 7:30 - 9:30 p.m.
An evening to learn and explore the ancient
and contemporary spiritual practice of spiritual direction.
Believers and seekers of God in every age have sought
to listen for the voice of God in their lives. The Church
over the centuries has had the gift of spiritual direction
to assist belivers in their quest of God. Come and possibly
discover something new for you! Fee: $15 p.p. Registration
Explore Prayer
- A workshop to discover variety of prayer forms - Wednesday,
September 16th, 9:30 to 11:30 a.m. "Teach
us to pray" was one of the earliest requests to
Jesus from his diciples, and today we seek to discover
the secrets of true prayer - connectedness to God! This
workshop will explore a variety of prayer forms from
the Catholic/Christian tradition and how one's temperment
may be best suited for one or more forms of prayer.
Come and explore! Fee: $15 p.p. Registration required.
What is Pope Francis up to in
His Visit to the U.S.? Wednesday, September 16th, 7:30
to 9:30 p.m. OR Thursday, September 17th, 9:30 to 11:30
a.m. What is the World
Meeting of Families all about? What will Pope Francis
be discussing in his visit to Philadelphia. Come and
explore the Pope's theology and how it has shaped his
shepherding of the Roman Catholic Church. If you are
interested in the Pope; if you are interested in what
he has to say regarding families; if you are interested
in the life of the Church today... this seminar is for
you! Fee: $15 p.p., Registration required.
Date Night! Married
Couples Evening of Reflection - Tuesday, September 29th,
7:00 to 9:30 p.m. No cooking. No cleaning.
Just a wonderful evening out with your beloved! A great
way to enjoy a night out together and to develop your
spiritual life as a couple. Come and enjoy. Four course
dinner beginning with Happy 1/2 Hour and ending with
an amazing dessert awaits! Come and treat yourselves
and see that in doing so you leave doubly blessed! Fee:
$60 per couple.
Sign Up Here!
for a Location for Your Event?
We are now accepting reservations
for you or your group's next one-day or multi-day retreat,
day or evening program in faith and ministry development,
prayer experience, special event, and more.
contact us to make MorningStar
your place for spiritual renewal.
MorningStar Renewal Center
7275 SW 124 Street
Miami, FL 33156-5324
Phone 305-238-4367
Fax: 305-238-4766
MorningStar! Become a regular donor!
Out Our Recent Events from the Summer! Make You Plans
Today to be at One of Our Next Grace Filled Programs!!!
& Spirituality Classes
Peer Ministry Weeklong Graduated 30 Highschool Students
into our Active Peer Ministry Program
Bernie, the Official
Mascot of the Miami Heat, visits MorningStar! Camp kids
have a blast seeing Burnie and the Championship trophy
he brought to show off!


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Editors' Note: The VLC Media Player source code is also available.
Publisher's Description+
VLC (initially VideoLAN Client) is a highly portable multimedia player for various audio and video formats, including MPEG-1, MPEG-2, MPEG-4, DivX, MP3, and OGG, as well as for DVDs, VCDs, and various streaming protocols. It also can be used as a server for unicast or multicast streams in IPv4 or IPv6 on a high-bandwidth network.
What's new in this version:
With faster decoding on multi-core, GPU, and mobile hardware and the ability to open more formats, notably professional, HD and 10bits codecs, 2.0 is a major upgrade for VLC.
Twoflower has a new rendering pipeline for video, with higher quality subtitles, and new video filters to enhance your videos.
It supports many new devices and BluRay Discs (experimental).
Completely reworked Mac and Web interfaces and improvements in the other interfaces make VLC easier than ever... See all new features »


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Bulova Dalton Walnut Mantel ClockItem # HN-BV323
- Wood and wood veneer case in walnut finish
- Westminster chime on the hour
- Spun, gold-finished pendulum and bezel
- Runs on one AA battery, not included
- 9.5H x 6.25W x 3.75D inches
Similar Mantel Clocks
Bulova Chadbourne Tambour Mantel Clock
Polaris Clock - Whirl Green Onyx
Howard Miller Bedford Mantel Clock
Seiko Marion Carriage Mantel Clock
Prescott Hanging Clock
Seiko Brown Alder Mantel Clock
Reviewed by 2 customers
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- Attractive Design
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Comments about Bulova Dalton Walnut Tabletop Clock:
The clock arrived nicely packed exactly when it was suppose to. It was a gift, so we were especially happy that is was all that it said it would be. This was our first time ordering from this company, but I'm sure that it won't be the last.
- Primary use:
- Personal
- Attractive Design
- Clear Display
- Keeps Good Time
- Reliable
- None
Best Uses
- Decoration
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Comments about Bulova Dalton Walnut Tabletop Clock:
Love it.
- Primary use:
- Personal
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when you join
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Enter your question, and one of our Customer Care experts will respond via email and also post the answer here.
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Free shipping on orders over $75*
…a secure fit are a must. The Cross-4 wetshoe is built with 4 mm neoprene for reliable insulation, and a supportive instep strap that ensures your shoes stay snug on your feet. * Adjustable instep strap tightens the top of the boot around your foot for increased stability and a comfortable, secure…
Related Products: Neoprene Boots | Cross 4 | Nrs Titanium Boots | Kayak Boots
Cold feet make for cold, miserable children. Miserable kids make for miserable parents. NRS Youth 2mm Wetsocks are perfect for wearing in a sandal for warmth or in a wetshoe for added protection. * 2mm neoprene with titanium laminate adhesive keeps little toes warm and happy. * Flat lock stitching…
Related Products: Neoprene Socks | Kids Water Shoes | Wetshoes | Youth
…neoprene panel is color-coded for easy identification of size in commercial use. * The 3-mm neoprene upper and a 5-mm neoprene insole make this paddle shoe warm and comfortable. * The flexible rubber sole offers high-traction support and protection from rocks and other sharp, pointy objects. * The…
Related Products: Neoprene Booties | Neoprene Boots | Booties | River Shoes
Intl: +001.208.882.6704
Buy the gift that's always welcome and always fits.
Tips, stories, and sales!
NRS | 2009 S. Main St. Moscow, ID 83843 | 877.677.4327 | firstname.lastname@example.com | © 2015 All Rights Reserved.


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NYC Parks Events Calendar
Get up, get out, and do something! Just about any day of the year, you can find something fun, informative, and healthy to enjoy at an area park. Feel free to browse the listings below, or use the search tools to find an event that matches your interests and location.
Viewing 1,251–1,260 out of 16,520 events
from November 3, 2013 (x) to April 25, 2026
Friday, October 10, 2014
Lola Star's Dreamland Roller Disco: Thriller Halloween Extravaganza - Michael Jackson Skate Party
at Lefrak Center at Lakeside (in Prospect Park), Brooklyn
8:00 p.m.–10:30 p.m.
Halloween is just around the corner. Lola Star is throwing her spookiest Roller Disco costumed party to celebrate the King of Pop at Dreamland in Prospect Park.
Category: Dance, Halloween
Saturday, October 11, 2014
Bird Walk with NYC Audubon
at Van Cortlandt Nature Center (in Van Cortlandt Park), Bronx
8:00 a.m.–9:00 a.m.
NYC Audubon experts lead the way as we marvel at quirky but logical bird behavior and delicate feathers in exquisite patterns. Bring binoculars if you have them and wear sturdy…
Category: Birding, Nature
Van Cortlandt Track Club
at Van Cortlandt Stadium (in Van Cortlandt Park), Bronx
8:00 a.m.–9:00 a.m.
Van Cortlandt Track Club runs through and around the Yonkers-Bronx border in small groups. For local running tips, visit vctc.org.
Category: Fitness, Sports, Outdoor Fitness
Greenmarket at Grand Army Plaza
at Grand Army Plaza, Brooklyn
8:00 a.m.–4:00 p.m.
Fresh produce and so much more, all year long! See what farm fresh is all about.
Category: Markets, Food
GrowNYC Greenmarket
at Socrates Sculpture Park, Queens
8:00 a.m.–4:00 p.m.
This market serves the Long Island City and Astoria communities with farm-fresh fruits and vegetables and family-friendly activities every Saturday.
Category: Markets, Food
4th Bienal de Arte Latinoamericano del Bronx: Open For Discussion
at Poe Park Visitor Center (in Poe Park), Bronx
8:00 a.m.–4:00 p.m.
The exhibition suggests that art discussion is inherently an expression of populism and protest; therefore it is important not to deny the mass attraction to it.
Category: Art
Art in the Garden: The Evolution of an Artist
at Queens Botanical Garden, Queens
8:00 a.m.–6:00 p.m.
Art in the Garden: The Evolution of an Artist Tuesday, September 30 through Sunday, January 17, in the Visitor & Administration Building Gallery Fee: Free with…
Category: Art
2014 Emerging Artist Fellowship Exhibition at Socrates Sculpture Park
at Socrates Sculpture Park, Queens
8:00 a.m.–6:00 p.m.
The annual Emerging Artist Fellowship Exhibition is a cornerstone of the park's visual arts program and is widely acclaimed for the ambition, breadth & innovation of the works on view.
Category: Art, Waterfront
Morning Fitness at Fort Tryon Park
at Heather Garden (in Fort Tryon Park), Manhattan
8:30 a.m.–9:30 a.m.
Join us for one hour of walking, stretching, and strengthening exercises.
Category: Fitness
The NY World's Fairs and the Port Authority Bringing Trade, Travel and Tourism to Queens, The Region and the World
at Queens Botanical Garden, Queens
8:30 a.m.–5:30 p.m.
In our continuing celebration of the New York World's Fairs, enjoy this Port Authority multimedia exhibit.
Category: Art, History
Pages:< Prev1…123124125126127128129…1652Next >
Related Information
- Get information on upcoming events directly in your inbox by signing up for our Email Newsletters.
- Know about an event that's not on the calendar? Send us a tip!
- Planning an event and considering hosting it in a park? Make sure to read our Planning an Event page.


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Mon-Fri: 10:00AM - 9:00PM
Sat: 10:00AM - 9:00PM
Sun: 11:00AM - 6:00PM
sign up to receive emails about new product from lululemon athletica (you can unsubscribe at any time)
Thank you for signing up to our email newsletter.
We are experiencing technical difficulties and were not able to add you to our subscriber list. Please try again later.
Join us for this complimentary yoga class + intention setting for race-day prep with our ambassador Justin Blazejewski.
A yoga class with some lecture discussing how to set an INTENTION and visualization to break through the walls we create in our mind.'
All-levels class, designed for runners prepping for their fall races!
Bring your mat (we have a few at the store to borrow!)
Join us for a 4-6 mile loop around Arlington - we change the route every month, third week of the month we have a speed workout and end the run at South Block Juice Co. for complimentary cold-pressed juice (thanks South Block!)
Meet at the store, we have space for you to stash your stuff while you run!
All levels welcome - we have an advanced pace group and beginner paced group, both led by lululemon staff.
Check out our Run Club Facebook group for more info: https://www.facebook.com/groups/144740159022311/
Join us for complimentary in-store yoga with Claire Reynolds from Down Dog Yoga!
All-levels, vinyasa style. Bring your mat (we've got a few at the store to borrow!)


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Effectiveness of a jail-based treatment program for individuals with co-occurring disorders
ABSTRACT This study examines the effectiveness of a county jail program for individuals with co-occurring disorders (COD) in reducing rates of recidivism and increasing rates of engagement in community-based treatment following discharge.
Over a period of 30 months, between 2002 and 2004, 261 individuals who screened positive for COD voluntarily entered an in-jail treatment program. The program provided integrated treatment for both mental health and substance abuse by therapists who had attended a state sponsored COD core training curriculum. The same program staff provided outpatient services once individuals were discharged. An observational study design was used to examine jail recidivism and community care as a function of intensity of treatment while in jail. All study participants had a minimum one year follow-up. Data was obtained from a baseline comprehensive screening instrument, administrative claims data and county jail records. Logistic regression models were used to determine the likelihood of re-incarceration and community engagement in treatment as a function of the number of treatment sessions provided by the jail program.
County jail records indicated that 47.5% were re-incarcerated within 12 months of discharge. During the four and a half year period following the inception of the COD program 67% were re-incarcerated, which was similar to the national three year recidivism rate. Fifty-two percent (52%) attended a community-based treatment program post discharge. The results of the regression analysis showed that a higher number of treatment sessions in the jail COD program was significant in reducing the rate of re-incarceration but was not significant in predicting who would engage in outpatient treatment post discharge.
Although the findings are promising, the evidence suggests that the jail treatment intervention may need to be more intense than the outpatient model used in this project given that the average length of stay in the jail program was 8 weeks due to release to the community. An alternative consideration would be to only provide the program to those inmates who are sentenced for at least 90 days.
Article: Mental disorders in prisons.[Show abstract] [Hide abstract]
ABSTRACT: The existence of people with mental disorders in prisons is a reality found worldwide. The purpose of this article is not only to review the publications on this subject in 2009 but also to stimulate discussions that could contribute to its further scientific study. Most studies published in 2009 related to drug use among inmates and its consequences made it clear that this kind of disorder has a closer relationship with the crime than with mental illness. The existence of the mentally ill in prisons is a complex issue and the studies attempt to analyze aspects such as the type of disorder, sex of criminals, the opposition between incarceration and treatment, policy, harm reduction and stigma. A further study on the variables raised in this work is required, as well as examining others, to the extent that they are relevant to the various socio-economic and cultural realities.Current opinion in psychiatry 09/2010; 23(5):463-6. DOI:10.1097/YCO.0b013e32833bb32f · 3.94 Impact Factor
Article: Can We Address the Shortage of Psychiatrists in the Correctional Setting with Exposure During Residency Training?[Show abstract] [Hide abstract]
ABSTRACT: Psychiatry residents at the University of Texas Southwestern Medical Center were surveyed to investigate their attitudes towards inmates, towards various aspects of correctional psychiatry and whether rotating at the local jail is associated with these attitudes. The overall opinion towards correctional psychiatry was fairly neutral though significantly more negative than towards inpatient psychiatry. While citing a high need for psychiatrists at correctional facilities, residents reported they are not likely to work there when they complete residency. No statistical differences were found between those residents who had rotated at the local jail and those who had not. Given the severe shortage of mental health providers in correctional facilities it is important to expose residents to this and understand ways to promote correctional psychiatry as a career.Community Mental Health Journal 03/2012; 48(6). DOI:10.1007/s10597-012-9512-3 · 1.03 Impact Factor
- The Journal for Nurse Practitioners 03/2013; 9(3):177-179. DOI:10.1016/j.nurpra.2012.12.016


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This forum thread is dedicated to all comments related to the content named: "Chuck Edel - Sports Betting Picks - Free Picks - Handicapper - Pregame.com"Located at: http://pregame.com/pregamepros/pro-bettor/bettor.aspx?id=74401.Forum replies to this thread are displayed: - in this thread- on the content pageComments made on the content page are displayed:- on the content page- in this threadMeaning that the entire conversation for this content is mirrored in two locations.
RJ Bell - Pregame.com Founder & CEO | Twitter: @RJinVegasNFL Week 5: Wiseguy NFL recaps from Wiseguy Steve Fezzik
Chuck Edel's Pregame Pro's HomepageFollow Chuck on Twitter @chuckedelBaseball Betting Tips from Chuck Edel & Johnny Detroit
www.jrodonnell.com ....currently on a 1172 1058 + 18.9 units a 100 $ bettor +1890 since 01/01/2014 All Sports Run & a 343-277 3* 55% ..NOW WE KEEP THE HAMMER DOWN ...... let's do this... AS THE DRIVE FOR 200 Units IS ON!!!!!!!!
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Summer Infant
Bassinet with Motion- Baby Time
$ 109 Gilt
$ 120
Prep for every important first with easy-to-use strollers, high chairs, and more.
Keep them comfy with the softest layette staples
Put a seasonal stamp on their space with sunny patterns and soft pastel hues.
Standout picks from the week's most in-demand sales.


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The baseball season is once again underway and that got me thinking about the business of sports. Once upon a time, there were a number of public companies that owned sports teams, especially baseball clubs. Presently, given that Sam Zell has taken the Tribune Company private, there remains only one baseball team with public company ownership and that's the Toronto Blue Jays, part of the Rogers Communications media empire. This doesn't leave the average Joe with much choice. There has to be a better way, and there is.
Buying sports franchises has always been attractive to the wealthy. Who wouldn't want to be a sports baron? However, if you're looking to make money you best look elsewhere. For those lacking a billion dollars or more to be a part of the fraternity that is sports ownership, here are three sports-related companies that you can invest in that will make you money long-term without the steep price of admission.
Adams Golf (Nasdaq:ADGF)
It's not a big company, but it's an important one. Founder Barney Adams created the Tight Lies fairway wood in 1999, revolutionizing the golf business. Since then the company has created many innovative products, most notably the Idea hybrid club, which combines the best attributes of both woods and irons, making it much easier to hit the ball, according to Adams Golf anyway. Legions of duffers may disagree.
As a company, Adams has experienced its own share of difficulties. However, today it's in the best shape it's ever been both financially and operationally in its 21-year history. Sales in 2007 were $94.6 million with an operating profit of $4.1 million, in comparison to sales of $76 million and an operating profit of $3.4 million in the previous year. Return on equity in 2007 was 17.6%, the second highest rate of return to shareholders in company history. On a valuation basis, Adam's Golf is a bargain trading at 0.55 times sales and 0.97 times book value. Swing away. (To learn how to make all these numbers and ratios work for you, check out our Fundamental Analysis Tutorial.)
International Speedway (Nasdaq:ISCA)
If you haven't heard of the Daytona Speedway, you're probably not a sports fan. Daytona is the crown jewel in a star-studded line-up of 13 racetracks coast-to-coast owned by the Florida-based company International Speedway. Bill France, Sr. built the business from the ground up, including co-founding NASCAR in 1948 and building the 2.5-mile super speedway at Daytona in 1959. Since then, the company has gone on to build or acquire venues in California, Michigan and Virginia, among others.
As an investment, it's been a bumpy ride. International Speedway stock sits at low prices not seen since August 2003 and nowhere near $66, its all-time high reached in November 1999. In the last 10 years, EBIT margins have shrunk to 21.5% from 34.7%. It's no wonder the stock's annual return in the last 10 years is 6%, barely better than the S&P 500's 4%. You'd think with NASCAR's popularity, the stock would have done better.
Lifetime Fitness (NYSE:LTM)
Arguably, America's best and largest fitness operation, the Minneapolis-based Lifetime Fitness has 71 facilities in 16 states. Since going public in June 2004, its stock is up almost $13 from its IPO pricing of $18.50. Solid performance until you consider that six months ago, the stock was trading around $65. It seems that the market is worried that the party is over for Lifetime. This is likely an overreaction. Operating margins in each of the last five years were 20% or higher, with revenue increasing every year from $257 million in 2003 (pre-IPO) to $656 million in 2007. That's hardly a weakening business model. (For reading on measuring company efficiency, check out The Bottom Line On Margins.)
Critics point to a slowing membership growth rate, as seen in the fourth quarter of 2007 (12.5% increase year-over-year) this is down from a 15.1% year-over-year growth in the third quarter of 2007. The company says it was due to a combination of increased fees at some clubs to reduce overcrowding plus an economic slowdown. At 50% off, it could be worth taking the risk that the naysayers are wrong.
Bottom Line
Next time you're on the golf course, watching a stock car race or working out at the gym, remember there's the potential to make money from your leisure activities. You don't have to be a business tycoon like George Steinbrenner to profit from the wide world of sports. If you want to become a successful partial owner, just look for home run stocks.
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What Exactly Are Arbitrage Mutual Funds?Learn about arbitrage funds and how this type of investment generates profits by taking advantage of price differentials between the cash and futures markets.
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Ferrari's IPO: Ready to Roll or Poor Timing?Will Ferrari's shares move fast off the line only to sputter later?
Stock Analysis
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How to Win More by Losing Less in Today's MarketsThe further you fall, the harder it is to climb back up. It's a universal truth that is painfully apparent in the investing world.
Fundamental Analysis
Use Options Data To Predict Stock Market DirectionOptions market trading data can provide important insights about the direction of stocks and the overall market. Here's how to track it.
Stock Analysis
2 Oil Stocks to Buy Right Now (PSX,TSO)Can these two oil stocks buck the trend?
Investing News
What Alcoa's (AA) Breakup Means for InvestorsAlcoa plans to split into two companies. Is this a bullish catalyst for investors?
Stock Analysis
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Could a Rate Hike Send Stocks Higher?A rate hike would certainly alter the investment scene, but would it be for the better or worse?
Investing News
Corporate Bonds or Stocks: Which is Better Now?With market volatility high, you may think it is time to run for corporate bonds instead of stocks. Before you do take a deeper look into which is better.
How do dividends affect retained earnings?When a company issues a cash dividend to its shareholders, the retained earnings listed on the balance sheet are reduced ... Read Full Answer >>
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How does additional paid in capital affect retained earnings?Both additional paid-in capital and retained earnings are entries under the shareholders' equity section of a company's balance ... Read Full Answer >>
What types of capital are not considered share capital?The money a business uses to fund operations or growth is called capital, and there are a number of capital sources available. ... Read Full Answer >>
What is the difference between issued share capital and subscribed share capital?The difference between subscribed share capital and issued share capital is the former relates to the amount of stock for ... Read Full Answer >>


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Mga mini flash game, mga Shockwave 3d game, mga html 5 na game, mga Android game, mga Java game.
If the game freezes, just click inside it (games can get unresponsive if you click elsewhere on the page).
Blow away the competition!
You're the master of your own gaming experience in this better-than-ever sequel. Customize your own game controls, the game mode and difficulty, the number of players, enemies, and levels, the arena...even your character and outfit! The possibilities are, in a word, endless.


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LaCrosse® Mallard II Max-4 HD® 1,000-gram Thinsulate® Ultra Insulation Chest Waders
Item # WX2-581862
- Google+
- Details & Specs
LaCrosse® Mallard II Max-4 HD® 1,000-gram Thinsulate® UltraTM Insulation Waders. Impervious armor for the mighty hunter.
Naturally-insulated neoprene meets an outer layer of LaCrosse's abrasion-resistant Brush Tuff® material. This brings an added measure of in-the-field toughness to neoprene's stretchy, personalized fit! And with 1,000-gram Thinsulate® Ultra Insulation in the boots, these Waders provide the performance needed in all cold wading environments.Ditch your lame-duck waders for the Mallard II:
- 100% waterproof 3.5 mm stretch insulating neoprene upper
- 1,000-gram Thinsulate Ultra Insulation
- Puncture and abrasion resistance from LaCrosse® Brush Tuff bi-directional material
- Buckled shoulder straps can be used as a belt when folded down
- Polyurethane protective coating on knees and seat for added durability in high-wear areas
- Top-loading pocket, call holder, and hand warmer provide ample accessible storage
- Realtree® Max-4 HD® camouflage
- Contoured Ankle-Fit design in boot to prevent heel slippage
- Swamp-Lite outsole provides superior traction in snow, mud and loose terrain
- 10 lbs. per pair.
State Size, as available in the Shopping Cart.
- Reviews
<!--BVSEO|dz:Main_Site-en_US|sdk:v188.8.131.52-n|msg:Error: Request errored out - The remote server returned an error: (403) Forbidden. -->
- Articles & Tips
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Rack 'em Boot Rack, Matte BlackNon-Member $24.99 Buyer's Club $22.49
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Guide Gear 3.5mm Boot Waders, Double BrownNon-Member $59.99 Buyer's Club $59.99


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Winning Abstracts from the 2013 Medical Student Abstract Competition: Olmesartan: An Unusual Cause of Celiac Sprue-like Enteropathy
Author: Stephanie E. Dreifuss, University of Pittsburgh School of Medicine, Class of 2014
We present a 64-year-old male with a past medical history of hypertension who presented with diarrhea and 12 kilogram weight loss over the preceding three months. He reported 3-10 daily episodes of fatty, non-bloody diarrhea with associated abdominal pain, bloating, and distention. He denied any changes in his diet or medications (olmesartan 40mg daily and omeprazole 40mg daily) within the last few years. He had a recent hospitalization for prerenal acute kidney injury (AKI) secondary to intractable diarrhea.
Stool cultures, Clostridium difficile toxin, and stool ova and parasites were negative. Stool osmolality, stool electrolytes, serum gastrin, serum VIP, and urine 5-HIAA were within normal limits. Fecal fat was elevated. A colonoscopy revealed no abnormalities. Small intestinal biopsy revealed villous blunting and intraepithelial lymphocyte infiltration. Based on the biopsy results and fecal fat elevation, celiac sprue was suspected. Therefore, the patient was instructed to begin a gluten-free diet, and serologic studies were ordered. IgA, anti-endomysial, and anti-tissue transglutaminase antibodies returned within normal limits, while the patient reported no improvement in his diarrhea.
He was admitted to the hospital three weeks later with dehydration, AKI, and orthostatic hypotension. Given his blood pressure of 83/48, olmesartan was discontinued. At a two week follow-up, he reported complete resolution of his diarrhea. He was gaining weight, having only one formed bowel movement daily, and beginning to reintroduce gluten into his diet. Amlodipine was started in place of olmesartan. Two months later, he reports having no diarrhea.
We report this case for two important reasons. First, we aim to alert clinicians of an unusual entity to include in the differential diagnosis of chronic diarrhea. The clinical features of this enteropathy include gastrointestinal symptoms (chronic diarrhea, weight loss, steatorrhea), negative serology (IgA tissue transglutaminase or endomysial antibodies), histologic evidence of enteropathy (villous atrophy and intraepithelial lymphocytosis), lack of improvement in symptoms with a gluten-free diet, exclusion of other causes of enteropathy, and evidence of improvement after discontinuing olmesartan. The findings in this case are similar to another case series in the literature (Mayo Clin Proc 2012;87:732). Our second objective is to emphasize the potentially dramatic consequences of drugs we prescribe. In this case, our patient endured three months of repeat hospitalizations, invasive tests, and weight loss before the offending drug was discontinued.
Further investigation is needed to elucidate the specific mechanism of olmesartan-associated enteropathy and to determine whether other ARBs elicit similar adverse reactions. Until these questions are answered, it is important for clinicians to maintain a high index of suspicion for olmesartan, and potentially other ARBs, as precipitants of a celiac sprue-like picture.
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With No Rings Till The End Of The Year Star Wars saga has new secrets Drew Goddart opened 3 mysteries about Martian MORE ›
Lyrics/song texts are property and copyright of their owners and provided for educational purposes only.
Weighty Ghost Lyrics
Weighty Ghost Song Lyrics
I got out of bed today,
Swear to God I couldn't see my face
I got out of bed today staring at a ghost
Who forgot to float away, didn't have all that much to say
Wouldn't even tell me his own name
Where'd my body go
Where oh where'd my body go?
Africa or Mexico?
Where or where'd my body go?
Where'd my body go?
Have you seen my ghost?
Staring at the ground?
Have you seen my ghost?
Sick of those goddamn clouds
Are you some kind of medicine man?
Cut the demons out of my head
You can't kill something that's already dead
Just leave my soul alone
I don't need no surgery
Take those knives away from me
Just wanna die in my own body
A ghost just needs a home
One Week Song List
›Hard Road
Sam Roberts
›Imaginary Bars
Great Lake Swimmers
›Skyway Bridge
Melissa McClelland
›Calendar Girl
›Weighty Ghost
›Blackwinged Bird
Emm Gryner
›The Great Escape
Patrick Watson
›Ricky Come Home
Andrew Heintzman / Fried Up Fred and Co.
›Un Canadien Errant
Melissa McClelland / Luke Doucet
›A Million Dollars
Joel Plaskett
›Oh, Canada
Hugh Oliver


text:
Page 1
Vascular Health and Risk Management 2007:3(3) 245–254
© 2007 Dove Medical Press Limited. All rights reserved
Combining insulins for optimal blood glucose
control in type 1 and 2 diabetes: Focus on insulin
Heather Ulrich1,4
Benjamin Snyder1
Satish K Garg1,2,3
1Barbara Davis Center for Childhood
Diabetes; 2Department of Medicine;
3Pediatrics; 4Department of Clinical
Pharmacy, School of Pharmacy,
University of Colorado at Denver and
Health Sciences Center, Denver, CO,
Correspondence: Satish K Garg
University of Colorado at Denver and
Health Sciences Center, 1775 N. Ursula
Street, Aurora, Colorado 80010, USA
Heather Ulrich
Department of Clinical Pharmacy,
University of Colorado at Denver and
Health Sciences Center, 4200 E. 9th
Avenue, Denver, CO 80232, USA
Tel +1(303) 315 1131
Fax +1(303) 315 1797
Email firstname.lastname@example.com
Abstract: Normalization of blood glucose is essential for the prevention of diabetes mellitus
(DM)-related microvascular and macrovascular complications. Despite substantial literature to
support the benefi ts of glucose lowering and clear treatment targets, glycemic control remains
suboptimal for most people with DM in the United States. Pharmacokinetic limitations of
conventional insulins have been a barrier to achieving treatment targets secondary to adverse
effects such as hypoglycemia and weight gain. Recombinant DNA technology has allowed
modifi cation of the insulin molecule to produce insulin analogues that overcome these phar-
macokinetic limitations. With time action profi les that more closely mimic physiologic insulin
secretion, rapid acting insulin analogues (RAAs) reduce post-prandial glucose excursions and
hypoglycemia when compared to regular human insulin (RHI). Insulin glulisine (Apidra®) is a
rapid-acting insulin analogue created by substituting lysine for asparagine at position B3 and
glutamic acid for lysine at position B29 on the B chain of human insulin. The quick absorption
of insulin glulisine more closely reproduces physiologic fi rst-phase insulin secretion and its
rapid acting profi le is maintained across patient subtypes. Clinical trials have demonstrated
comparable or greater effi cacy of insulin glulisine versus insulin lispro or RHI, respectively.
Effi cacy is maintained even when insulin glulisine is administered post-meal. In addition,
glulisine appears to have a more rapid time action profi le compared with insulin lispro across
various body mass indexes (BMIs). The safety and tolerability profi le of insulin glulisine is also
comparable to that of insulin lispro or RHI in type 1 or 2 DM and it has been shown to be as
safe and effective when used in a continuous subcutaneous insulin infusion (CSII). In summary,
insulin glulisine is a safe, effective, and well tolerated rapid-acting insulin analogue across all
BMIs and a worthy option for prandial glucose control in type 1 or 2 DM.
Keywords: glycemic control, glycosylated hemoglobin A1c (HbA1c), rapid-acting insulin
analogues, type 1 diabetes mellitus, type 2 diabetes mellitus, insulin glulisine, body mass
index (BMI).
The prevalence of diabetes mellitus (DM) is increasing at an alarming rate largely
due to an aging population coupled with high rates of obesity, unhealthy diet, and
sedentary lifestyle (IDF 2006). An estimated 7% of the United States population,
or >20.8 million Americans, have type 1 or type 2 DM, representing a 14% increase
in prevalence over the last 2 years (ADA 2006). Furthermore, >41 million Americans
have impaired glucose tolerance (IGT) or impaired fasting glucose (IFG), conditions
classifi ed as pre-diabetes because they signifi cantly increase an individual's risk for the
development of diabetes; the expected conversion rate to diabetes for such persons is
7% per year (ADA 2006). Statistics are equally sobering for the European population.
The current prevalence of 7.8% is expected to increase to 9.1%, roughly 60 million
Europeans, by the year 2025 (IDF 2006).
Page 2
Vascular Health and Risk Management 2007:3(3)
Ulrich et al
The impact of DM on society and the persons affected
is profound. Both type 1 and 2 DM are associated with
microvascular and macrovascular complications that result
in considerable morbidity and an estimated 3.2 million deaths
per year worldwide (World Health Organization 2006).
Although there has been an overall decrease in mortality
from coronary artery disease in patients without DM over
the last 10 years, there has been a paradoxical increase in
DM-related mortality (Sobel et al 2003). Despite these sta-
tistics, this disease can be well managed with individualized
intensive treatment regimens.
Blood glucose lowering is essential for the prevention
of DM-related microvascular and macrovascular complica-
tions. The Diabetes Control and Complications Trial (DCCT)
found that intensive insulin therapy to improve glycemic
control, as measured by glycosylated hemoglobin (A1c),
signifi cantly lowered the risk for retinopathy by 47%, for
nephropathy by 54%, and for neuropathy by 60% in patients
with type 1 DM followed for an average of 6.5 years (The
Diabetes Control and Complications Trial Research Group
1993). Similar fi ndings with intensive treatment were seen
with large cohorts of patients with type 2 DM followed in the
United Kingdom Prospective Diabetes Study (UKPDS) and
the Kumamoto studies (UKPDS 1998; Shichiri et al 2000). It
is estimated that for every percentage point A1c is lowered,
the risk of microvascular complications is decreased by 37%
and the risk of macrovascular complications is decreased
14% (Stratton et al 2000).
More recent data comes from the Epidemiology of Dia-
betes and Interventions and Complications (EDIC) trial, a
follow-up study of the DCCT that analyzed study participant
data for up to 18 years (Nathan et al 2005). In addition to
observing continued reductions in microvascular complica-
tions, researchers found that intensive therapy during the
DCCT years was associated with a 42% reduction in the risk
of cardiovascular disease and a 57% reduction in cardiovas-
cular events, including myocardial infarction, stroke, and
death. Overall, every 10% reduction in A1c (ie, a decrease
from an A1c of 8.0% to 7.2%) was associated with a 21%
decrease in cardiovascular disease.
The American Diabetes Association (ADA), the Ameri-
can Association of Clinical Endocrinologists (AACE), and
the International Diabetes Federation (IDF) recommend
near-normalization of plasma glucose levels with target
A1c values of <7.0%, ?6.5%, and ?6.5%, respectively
(IDF 1999; AACE 2002; ADA 2006). Although the ADA
recommends an A1c goal of <7.0% for patients in general,
the goal for individual patients should be set as close to nor-
mal (<6.0%) as possible without signifi cant hypoglycemia
(ADA 2006). Each organization also provides specifi c
goals for fasting plasma glucose (FPG) and postprandial
glucose (PPG) (see Table 1) (ADA 2006; AACE 2002;
Despite substantial literature to support the benefi ts of
glucose lowering, clear treatment targets, and the avail-
ability of effective treatments, the average A1c in the
United States remains above 9% (Hirsch 2004). For several
decades, pharmacokinetic limitations of conventional
insulins made treatment goals diffi cult to achieve for many
patients. Studies have shown that intensive regimens with
these older insulins often results in frequent hypoglycemia,
weight gain, glucose variability, and wide glucose fl uctua-
tions (Diabetes Control and Complications Trial Research
Group 1993; UKPDS 1998). However, the development
of recombinant DNA technology has allowed modifi cation
of the insulin molecule to produce insulin analogues with
more physiologic time-action profi les (see Table 2) (Garg
and Ulrich 2006). This article discusses the benefi ts of
intensive insulin regimens designed to mimic physiologi-
cal basal/bolus insulin secretion, with a focus on the new
rapid-acting insulin analogue, glulisine.
Type 1 DM, which constitutes 5%–10% of the diabetic popu-
lation, occurs when autoimmune destruction of the β-cells
leads to absolute insulin defi ciency. Patients with type 1 DM
are therefore dependent on exogenous insulin replacement
for survival. Type 2 DM, the more common form of the
disease, results from a combination of relative insulin defi -
ciency and a defect in insulin action, or insulin resistance,
which is frequently associated with obesity. Initially, patients
Table 1 Treatment goals for glycemia (% of patients to targets)
2-h PPG(mg/dL)
ADA 2006: "The A1c goal for the individual patient is an A1c as close to normal
(<6%) as possible without signifi cant hypoglycemia".
Sources: ADA 2006. Standards of medical care in diabetes – 2006. Diabetes Care,
29(Suppl 1):S4-S42; AACE 2002. American College of Endocrinology. Medical guidelines
for the management of diabetes mellitus: The AACE system of intensive diabetes
self-management – 2002 update. Endocr Pract, 8(Suppl 1):40–82; IDF. 1999. A desktop
guide to type 2 diabetes mellitus. European Diabetes Policy Group 1999. Diabet Med,
Abbreviations: AACE, American Association of Clinical Endocrinologists; ADA,
American Diabetes Association; FPG, fasting plasma glucose; IDF, International
Diabetes Federation; PPG, postprandial glucose.
Page 3
Vascular Health and Risk Management 2007:3(3)
Insulin glulisine for blood glucose control in diabetes
with insulin resistance may have suffi cient β-cell function
to compensate for the increased peripheral insulin demand
(Plonsky et al 1996). However, once β-cell failure begins,
abnormalities in glycemia occur.
Patients with type 2 DM have a loss of fi rst phase
insulin release from pancreatic β-cells, which results in
PPG excursions (Plonsky et al 1996). Furthermore, as the
disease progresses, the β-cells lose the ability to maintain
suffi cient basal insulin secretion leading to increased FPG
(Plonsky et al 1996). In type 2 DM, there is an approxi-
mate 50% loss of β-cell function at the time of diagnosis,
followed by a gradual, yet progressive decline (UKPDS
1995). Chronic hyperglycemia may further impair β-cell
function and tissue sensitivity to insulin, resulting in an
even greater defi cit in insulin secretion and action (Rossetti
et al 1990).
Excessive post-prandial glucose excursions may elevate
A1c levels even when FPG remains in goal range (Monnier
et al 2003). Although A1c is determined by a combination
of fasting and PPG levels, the exact contribution of each
is not known. One study done using intermittent glucose
monitoring demonstrated that at higher A1c values
(A1c >8%), FPG had a more signifi cant infl uence on overall
control, however as patients got closer to target A1c, the post-
prandial component became the predominant factor. A more
recent trial conducted using continuous glucose monitoring
showed that FPG was normal only for patients with an A1c
<6% and that PPG continued to infl uence average glycemic
control even at higher A1c values (Figure 1) (Garg 2006).
Regardless of the exact role of FPG vs PPG, it is evident
that regimens must lower both fasting and post-prandial
hyperglycemia to achieve therapeutic goals.
Basal/bolus therapy
Intensive insulin therapy for patients with type 1 DM should
consist of a basal/bolus regimen which can be achieved with
a combination of long/intermediate and short- or rapid-acting
insulins or a continuous infusion of a short- or rapid-acting
insulin via an insulin pump. Unless a patient presents with
profound hyperglycemia, type 2 DM can and should be
initially managed with diet and exercise with or without the
addition of oral glucose-lowering medications. Lifestyle
modifi cations centered around diet, exercise, and weight loss
can have a profound effect on insulin sensitivity and should
be the fi rst step in the management of type 2 DM (ADA
2006). Specifi cally, overweight patients should be encour-
aged to achieve and maintain a weight loss of at least 7%
of total body weight through a healthy diet and 150 minutes
per week of moderate intensity exercise. Furthermore, the
Diabetes Prevention Program Research Study showed that
if these interventions are initiated early enough, they can
prevent or delay the progression of pre-diabetes to diabetes
(Diabetes Prevention Program Research Group 2002).
However, because type 2 DM is a progressive disease,
lifestyle interventions alone are often not sufficient to
maintain glycemic control over time (Turner et al 1999).
Most patients will require multiple pharmacological agents
to achieve glucose targets and eventually, as further β-cell
deterioration results in failure of the oral agents to control
hyperglycemia, many patients need insulin introduced
(Turner et al 1999; UKPDS 1995).
When utilized in patients with either type 1 or 2 DM, an
ideal intensive insulin regimen mimics endogenous basal and
prandial insulin secretion as closely as possible. Basal insulin
release regulates hepatic glucose homeostasis in the fasting
Table 2 Pharmacokinetic parameters of available insulins
Insulin preparations Onset of action Peak of action (h) Duration of action (h)
Regular human insulin
Insulin lispro 75/25
Insulin aspart 70/30
30–60 min
5–15 min
1–3 h
1–3 h
3–4 h
1–2 h
2–4 h
No peak
15 min
5–15 min
Adapted from Garg SK, Ulrich H. 2006. Achieving goal glycosylated hemoglobin levels in type 2 diabetes mellitus: practical strategies for success with insulin therapy. Insulin,
Page 4
Vascular Health and Risk Management 2007:3(3)
Ulrich et al
state and supplies approximately 50% of an individual's
overall insulin requirement (Wittlin et al 2002). The bolus
component of endogenous insulin secretion consists of
rapidly released short-lived bursts of insulin in response to
prandial stimuli. Postprandial insulin is released in a 2- to
5-minute burst (fi rst phase) followed by a slow increase in
insulin release lasting 5–52 minutes (second phase) (Wittlin
et al 2002). The fi rst-phase insulin secretion at mealtime
inhibits endogenous gluconeogenesis in the liver and disposal
of the carbohydrate load, thereby limiting PPG excursions.
Early normalization of glucose after a meal is important,
especially in type 2 DM to prevent late hyperinsulinemia and
prolonged stress on β-cells (Rossetti et al 1990).
Conventional insulin vs rapid acting
Regular human insulin (RHI) was the only short-acting
bolus insulin available for many years. Because it requires
the addition of zinc for stability, RHI exists as a molecular
hexamer that, once injected, must break down into dimers
and ultimately monomers to be absorbed and biologically
active (Wittlin et al 2002). Although RHI has advantages over
previously used pork and bovine insulins, its slower onset and
longer duration of action do not completely mimic endog-
enous insulin secretion after a carbohydrate load (Wittlin et al
2002). Patients should take injections 30–45 minutes prior
to a meal to prevent extended postprandial hyperglycemia
and subsequent hypoglycemia during its longer duration of
action. However, most patients do not follow this recommen-
dation (Overmann and Heinemann 1999). Furthermore, peak
concentrations may not occur until 2–4 hours after injection,
requiring frequent snacks to avoid hypoglycemia and thereby
increasing the potential for weight gain.
The advent of recombinant DNA technology using a
non-pathogenic strain of Escherichia coli (K12) has facili-
tated the development of insulin analogues that overcome
the pharmacokinetic limitations of RHI. Amino acid sub-
stitutions in the insulin molecule allows weak dimeric and
hexamer formation and thereby rapid disassociation of the
dimers and hexamers after subcutaneous injection, resulting
Figure 1 Fasting glucose (12 fasting glucose (12–7 am) vs A1c. Reproduced with permission from Garg S. 2006. Safety, accuracy, and improvement in glucose profi les
observed using a 7-day continuous glucose sensor. Diabetes Care®, 29:2644-9. Copyright © 2006 American Diabetes Association.
Baseline Hemoglobin A1C (%)
Mean Sensor Glucose From 12 to 7am (mg/dL)
121.0149.8 166.6 211.8186.3255.0 129.7140.1164.8 188.4182.3
Page 5
Vascular Health and Risk Management 2007:3(3)
Insulin glulisine for blood glucose control in diabetes
in rapid absorption and onset of action (Howey et al 1994).
Currently available rapid acting analogues (RAAs), which
include insulin lispro, insulin aspart, and insulin glulisine,
demonstrate less variability in absorption at the injection
site and potentially less variability in and among patients
(Howey et al 1994). RAAs have shown greater effi cacy in
reducing post-prandial glucose excursions and hypoglycemia
when compared with RHI (Anderson et al 1997; Home et al
1998; Garg et al 1999). A meta-analysis of comparative tri-
als with insulin lispro and RHI reported a 25% reduction in
the frequency of severe hypoglycemia (Brunelle et al 1998).
Some, but not all trials have shown modest reductions in A1c
with these analogues. One meta-analysis noted a small but
signifi cant decrease of –0.12% in A1c with RAAs vs RHI in
patients with type 1 DM; however, this benefi t was not seen
with the type 2 DM population (Plank et al 2005).
Insulin glulisine
Insulin glulisine (Apidra®) is a rapid-acting insulin analogue
created by making two amino acid substitutions in the B chain
of human insulin: lysine for asparagine at position B3 and
glutamic acid for lysine at position B29 (see Figure 2) (Garg
et al 2005). As with other RAAs these modifi cations to the
insulin molecule reduce its tendency to aggregate as hexam-
ers, allowing rapid dissociation and absorption following
a subcutaneous injection. The quick absorption of insulin
glulisine more closely reproduces physiologic fi rst-phase
insulin secretion.
Insulin glulisine is approved in the United States and
Europe for the treatment of type 1 and type 2 DM in adults.
It may be administered via subcutaneous injection (abdomen,
thigh, or deltoid) or CSII. When utilized as a prandial sub-
cutaneous injection, it should be given 15 minutes pre-meal
or within 20 minutes post-meal.
Insulin glulisine demonstrates equivalent bioeffi cacy with RHI.
In an initial randomized, open-label crossover study with 16
healthy volunteers (mean age = 22 years, mean body mass index
[BMI] = 23.9 kg/m2) the euglycemic clamp technique was used
to compare the molar effi cacy of the two insulins (Becker et al
2005). During a 2-hour continuous infusion, insulin glulisine and
RHI had superimposible mean glucose infusion rates (GIR) and
area under the glucose infusion rate time-curves at steady state
(GIR-AUCSS). Both insulins also presented equal total glucose
exposure as measured by the glucose infusion rate time-curve
from time 0 to clamp end (GIR-AUC0-clamp end). The overall
equivalent bioeffi cacy demonstrated that patients can switch
from RHI to insulin glulisine on a unit-per-unit basis. A random-
Figure 2 Glulisine vs RHI vs lispro: pharmacokinetics in obese individuals. Reproduced with permission from Garg SK, Ellis SL, Ulrich H. 2005. Insulin glulisine: a new rapid-
acting insulin analogue for the treatment of diabetes. Expert Opin Pharmacother, 6:643–51. Copyright © 2005 Informa Healthcare.
BMI = 30 kg/m2 to 40 kg/m2.
0 120 240
Time (min)
360 480600
Dosage = 0.3 U/kg.
Glucose Infusion Rate (mg.kg-1.min-1)


text:
Traditionally, track saws have been used for the sort of fussy cuts made while building cabinets or cutting inlays into flooring. But according Mark Ellis, a deck builder in Los Gatos, CA, there's no reason why deck builders shouldn't use them too. I agree; cabinet makers and finish carpenters are not the only ones who need to make straight clean cuts. On a recent project I used a track saw to trim the top of a fence straight and level and the bottom straight and parallel to the ground. It was a quick and easy way to do it and the results were better than they would have been if I'd cut freehand. Read more.
25 favorites from the outgoing editor.
David Frane
If Ron Paulk's original portable workbench was excellent (and it was), then this new...
For speedy deck demo, this tough tool is hard to beat
Some folks would say this isn't a tool. But it is.
Twice the batteries, twice the voltage, and more than twice the speed of the...
Please read our Content Guidelines before posting.
Check out Tool Videos from our Editors and Contributors
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2015 Hanley Wood Media, Inc. All rights reserved.


text:
Beautiful banners are coming to every article and you can help!
Check out our guidelines and learn how to create your own!
Check out our guidelines and learn how to create your own!
Tobermory (Scotland)
From Wikitravel
Hebrides : Inner Hebrides : Mull : Tobermory
Tobermory is the largest village on Mull, in Argyll and Bute.
Get in[edit]
Get around[edit]
See[edit][add listing]
Do[edit][add listing]
Buy[edit][add listing]
Food from the delicatessen in the Island Bakery.
Eat[edit][add listing]
From the Island Bakery [1]. Try Javier's restaurant.
Whilst on the harbour at Tobermory pick up fish and chips from the excellent van underneath the clock tower.
Drink[edit][add listing]
Sleep[edit][add listing]
Get out[edit]


text:
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Shoal Bay Surf Cam & Surf Report
@ 9 sec
9 min ago
L 1:40 PM (0.5m)
H 7:46 PM (1.6m)
L 2:01 AM (0.4m)
H 8:18 AM (1.5m)
Regional Surf Report
Surf Report Info
Region: Shoal Bay to Swansea
Reporters location:
Coastalwatch surf reporters are the saltiest locals around. Part fish, part shark, part human, they live for the waves and are usually more local than the locals. They'll be up before dawn waiting for first light to reveal the days surf conditions and can sense a change of wind from a sparrows fart. Each reporter covers a region of coastline which includes many number of surf spots and beaches. Please consider there may be possible variations between this report and your local spot due to differences in orientation to the coast and any local idiosyncrasies that may also effect the swell and weather patterns.
by Daniel Mason
10/10/2015 6:03 AM | Report
Today's rating - Average
ENE swell 2ft @ 10 seconds. W winds 3 knots. Small clean surf. Tide is up and it is looking pretty full on the beaches, high tide reefs will be the pick early. Wave quality should improve later in the morning once the tide starts to run back out. South facing beaches will be the pick once the wind swings to the NE.
Today's Outlook
Swell: 1m
Wind: W 0-10 kts
Best at: Open beaches
Conditions: Clean
Swell: 1m
Wind: NE 10-20 kts
Best at: South-facing beaches
Conditions: Semi-clean
Sponsor recommended
The best board for today is :
The best wetsuit for today is :
Tomorrow's Surf Forecast
@ 9 sec
Marine Outlook
Forecast for Saturday 10 October until midnight
Winds: Northeasterly 10 to 15 knots, reaching up to 20 knots north of Norah Head in the late evening.
Seas: Around 1 metre, increasing to 1 to 1.5 metres north of Norah Head.
Swell: Southerly below 1 metre. Weather: Partly cloudy.
UV Index 9 (Very High)
Bulls Paddock
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Jabba the Hut
View Single Post
July 8 2013, 06:24 AM
Fleet Admiral
Location: inside teacake
Re: Jabba the Hut
What I don't get about the FORCE if it's so super wonderful you can lift space ships with it why don't they just use the force to stop a person's heart? Is there something woowoo about the heart, that it is the life pump and the force cannot prevail against it? Vader can choke people, for the theater of it. But if he didn't need theater could he just squeeze their heart with the force and BOOM heart attack? That way you don't even have to work against the LIFE PUMP, you just squish it a little and biology freaks out and the person dies.
"Damnit Spock. God damnit!" Kirk ST:V
■ ■ ■
Janeway does Melbourne
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Hyundai car company has 5 new car dealers/showrooms in Chennai.
Address: Old Mahabalipuram Road, Sholinganalur - Nedavakkam Junction,Chennai, Tamil Nadu, 600101
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Brazil's Straw Hat project helps women leave abusive situations
Saudi, Iran and the 'war' over the Hajj stampede
08 Aug 2012 09:34 GMT | US & Canada, United Kingdom, United States
A Texas man convicted of killing a police informant has been executed after the US Supreme Court rejected arguments that he was too mentally impaired to qualify for the death penalty.
Marvin Wilson, 54, was pronounced dead late on Tuesday, 14 minutes after his lethal injection began at the state prison in Huntsville.
He was convicted of fatally shooting a police drug informant nearly 20 years ago in Beaumont.
Wilson's lawyers had argued that he should have been ineligible for capital punishment because of his low IQ. They cited a US Supreme Court ruling that banned capital punishment for the mentally impaired.
In their appeal to the high court, the lawyera pointed to a psychological test conducted in 2004 that pegged Wilson's IQ at 61, below the generally accepted minimum competency standard of 70.
But lower courts agreed with state attorneys, who argued that Wilson's claim was based on a single test that may have been faulty, and that his mental impairment claim was not supported by other tests and assessments of him over the years.
Stay of execution
The Supreme Court denied his request for a stay of execution less than two hours before his lethal injection began.
Lee Kovarsky, lead defence lawyer, said he was "gravely disappointed and saddened'' by the ruling, calling it "outrageous that the state of Texas continues to utilise unscientific guidelines ... to determine which citizens with intellectual disability are exempt from execution".
Commenting on the case, Simon Whitaker, a clinical psychologist from the UK, told Al Jazeera earlier on Tuesday: "This is a miscarriage of justice, he [Wilson] would have the same reasoning powers of a five-year-old child, if a five-year-old child killed someone we would not execute them in part.
"Texas courts have judged Wilson as not mentally retarded - even though psychologists measured his IQ in the bottom one percentile, about equal to that of an average five-year-old child.
"With his diagnosis he cannot make rational decisions, there will be a clear problem for him to think things through," said Whitaker.
Shot in the head
Wilson was convicted of murdering 21-year-old Jerry Williams in November 1992, several days after police seized 24 grammes of cocaine from Wilson's apartment and arrested him.
Witnesses testified that Wilson and another man, Andrew Lewis, beat Williams outside of a convenience store in Beaumont, about 128km east of Houston.
Wilson, who was free on bond, accused Williams of snitching on him about the drugs, they said.
Witnesses said Wilson and Lewis then abducted Williams, and neighbourhood residents said they heard a gunshot a short time later.
The next day, Williams was found dead on the side of a road, wearing only socks, severely beaten and shot in the head and neck at close range.
'Skirting the ban'
The Supreme Court issued a ruling in 2002 outlawing the execution of the mentally impaired, but left it to states to determine what constitutes mental impairment.
Kovarsky argued that Texas is trying to skirt the ban by altering the generally accepted definitions of mental impairment to the point where gaining relief for an inmate is "virtually unobtainable".
State attorneys say the court left it to states to develop appropriate standards for enforcing the ban and that Texas chose to incorporate a number of factors besides an inmate's IQ, including the inmate's adaptive behaviour and functioning.
Edward Marshall, a Texas assistant attorney general, said records show Wilson habitually gave less than full effort and "was manipulative and deceitful when it suited his interest'', and that the state considered his ability to show personal independence and social responsibility in making its determinations.
Laura Moye, director of Amnesty International's US death penalty abolition campaign, told Al Jazeera that her group was "disturbed and disappointed" by the failure of the Supreme Court to intervene in Wilson's case.
"We're not saying he shouldn't have been held responsible for his part in a terrible crime, but that it's an egregious act in a country that prides itself on its human rights record to put to death a man such as this one," Moye said hours after Wilson was executed.
"There are important human rights standards that the United States ought to adhere to, particularly because it's enshrined in our constitution that there are certain people who shouldn't face execution."
Texas is one of 33 states, along with the federal government, which still maintains the death penalty. A recent poll indicated more than 70 per cent of Texans approve of capital punishment for murder.
Source: Al Jazeera
Marvin Wilson, deemed by his lawyers to be clinically "mentally retarded", set to face lethal injection for murder.
US & Canada, United Kingdom, United States
In 2010, Michael Selsor granted his only interview to Josh Rushing. Two years later, Rushing returned to watch him die.
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Enbridge Energy is eyeing a major pipeline in Minnesota state, but the project faces fierce environmental opposition.
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101 East follows the lives of seven people in Nanjing and asks what they think of the direction their country is taking.
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Business & Economy, Arts & Culture, Poverty & Development
An investigation into the high rate of child sex abuse in Jamaica and the government's failure to protect its children.


text:
Dario C. Giannoni RitesNovember 14,2012
SHELBURNE — The funeral and service of remembrance for Dario Charles Giannoni, of the Shores at Shelburne Bay and Barre native, businessman and 32nd degree Mason, was held Monday Nov. 12, 2012, at 11 a.m. in the Hooker and Whitcomb Funeral Home, 7 Academy St., Barre. He died at his residence Nov. 8, 2012.
The Rev. Ralph Howe, pastor of the Hedding United Methodist Church of Barre, conducted the ceremony and led the congregation in the hymns "We Gather Together," "Onward Christian Soldiers" and "Amazing Grace."
The bearers were grandsons Alexander, Grey and Scott Switzer and nephews Larry Rossi and Paul and Charles Giannoni Jr. Burial was made in the Hope Cemetery where the Rev. Howe read the committal prayers.
The folded American flag was presented to his daughter, Mary Alice Giannoni, by Bruce W. Judd.
Fellowship and luncheon followed at the Mutuo Inc where Dario had been a longtime member.MORE IN ObituariesBRATTLEBORO Committal services and burial with full military honors for Michael W. Full StoryWASHINGTON A Mass of Christian burial and celebration of life for Ralph Paul Tenney, 84, was... Full StoryHARDWICK Edna Pearl Lafont, 93, of Hardwick, died Sept. 30, 2015, at the Greensboro Nursing Home. Full Story
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|ESPN.com: New York Hockey
|[Print without images]
"Dropping ... would seem like a bad thing, but look at it this way. Would you rather drop because a prospect has proven himself in the NHL? Or would you rather rank higher with doubts still swirling about how good your past draft picks can be? I'd take the bird in hand."
"Jon Merrill (38th overall, 2010) is in his sophomore season at the University of Michigan of the CCHA and has time to grow into his 6-3 frame while goaltender Scott Wedgewood (84th overall, 2010) is playing on a very strong Plymouth Whalers team in the OHL and some have suggested he should get a tryout for the World Juniors with Team Canada."


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VIDEO: Josh Gad 'Auditions' for STAR WARS Film on Jay Leno
1600 Penn star Josh Gad stopped by last night's TONIGHT SHOW WITH Jay Leno and decided to use the appearance to audition for J.J. Abrams upcoming Star Wars installment. "The sky's the limit -- from what I understand, they're gonna do all these different things. So I was thinking, why can't someone like me star in one of those films?...Why can't Leia and Han have an overweight son named Michael Solo?" Check out the appearance below!
Gad proceeded to take out a script from pocket and asked The Talk show host to read lines with him in thr role of Harrison Ford's Han Solo revealing that Gad's 'Michael Solo' would be "the fattest kid in Jedi school," dealing with "Grandpa Vader's breathing problems" and asking his father about the time "Mom and Uncle Luke almost hooked up on Endor."
"The Tonight Show with Jay Leno" features a nightly monologue (the longest in late-night), news-making guests, and ongoing comedy segments, including "Headlines," "Jaywalking" and "Battle of Jaywalking All-Stars." The result is a unique and humorous look at the daily happenings in the news and in pop culture.
The program is also a proven barometer of political clout. In 2009, the show made history by being the first late-night show to host a sitting president when Jay Leno welcomed President Barack Obama as a guest.
"The Tonight Show with Jay Leno" is from Big Dog Productions in association with Universal Television. Debbie Vickers is the executive producer.
About Author
- Sneak Peek - GMA's Amy Robach & More on Next OPRAH: WHERE ARE THEY NOW?
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Let your creativity shine with uniquely textured Bellini. With just one ball, you can make a statement scarf in an hour. Bellini is also great for adding colorful fringe trims to fashion items.
Please note that out-of-stock colors of this yarn will not be replenished, as this line is being phased out and no longer in production.
65% Acrylic, 20% Wool, 15% Polyester
Knit: 5 sts x 10 rows = 4 in. x 4 in. (10 cm x 10 cm) on size 11 (8 mm) knitting needlesCrochet: 5 sc x 8 rows = 4 in. x 4 in. (10 cm x 10 cm) on size N-13 (9 mm) hook
** Please note that all Lion Brand Yarn Company facilities are closed for religious observance on October 5th & 6th. We ask for your patience regarding correspondence during this time. **
Navy blue and rich red
Rich teal and deep blue
Magenta, violet, emerald, blue, brick red, and black


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Pine Lodge Motor Inn
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
Travel Blogs from Black River Falls
Day 9
... to Tollinois tomorrow (that is Illinois) but they have so many tolls it's ridiculous Hope to be near Youngstown Ohio tomorrow but thats another 685-700 miles so I am leaving it up to Shane where we end up as he is driving. Home here we ...
I have run away to live in Wisconsin!
... to the girl that I had a three year old who would need to be close to the playground as he has been in the car for almost 12 hours. She was kind enough to accommodate and put us right beside it. We ended up here at about 5:45pm due to the time change and it was a welcome break. :) The kids hit the park immediately while Bo and I set up, and then it was right to the pool and water park. We spent a good two hours at the pool - where we had to return to ...
So Where do I go from Here?
Besides starting to plan a return trip to the Delta?
Future Lesson Plan Ideas:
Comparison of the Upper and Lower Mississippi-- looking at geography, culture, history across time in the two regions-- and possibly developing an iBook for use on student iPads
Sharing information regarding Emmett Till Case ...
Just "Milling" Around and Down the Road
... in the right lane. The only good thing about it was when I passed a car the wind helped me get back in the correct lane. I just had to steer! Later we found out that we were in part of the very bad weather that came through that area. Luckily we were driving away from the biggest part of the storm.
We toured Warrens and blinked once quickly and were finished with the tour! Not even time for pictures nor were there any subjects for pictures!
We did go ...
Day 2 Osseo to Effingham
Left the campground at 8:00...55 degrees...odometer 33872.
Stopped for gas.......100.00 Visa.
Breakfast at Norske Nook.....Diane had eggs, bacon and hash browns, sour dough toast with lingonberry jelly, Joel had 3 large potato pancakes and bacon.......coffees to drink.....23.90 visa.
Stopped at Gordy's grocery.....Diane bought ...
Other places to stay in Black River Falls
Best Western Arrowhead Lodge & Suites600 Oasis Road, Black River Falls | 2 star hotelfrom $78
Black River Falls Days Inn919 Highway 54 East, Black River Falls | 2 star hotelfrom $67
Comfort Inn & Suites Black River FallsW10170 Hwy 54 East, Black River Falls | 2 star hotelfrom $104


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Take action today [2]to shut down the Line 5 pipelines and protect the Great Lakes from a potential pipeline disaste.
Line 5 carries nearly 23 million gallons of oil through a pair of 62 year old oil pipelines running along the bottom of the Mackinac Straits and threaten the Great Lakes, surrounding communities and Michigan's economy. The pipelines are owned by Enbridge, Inc., the Canadian company responsible for the spill of 1 million gallons of heavy tar sands oil into the Kalamazoo River watershed in 2010.


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Membership - Wiccan Church of Minnesota
The public version of the Church Newsletter
is available HERE (PDF)
Previous Voices
In the Belly of the Mother.
By Suki; Originally published in the 2010 Lammas Newsletter
I'm sad.
There were many valid reasons for some folks to miss this event:
Still, I'm also ecstatic for having had – and taken – the opportunity to attend this ritual.
This is a "living" cave – there is still water flowing through it and natural onyx is still growing in a cool, near-100% humidity atmosphere. To touch the walls or to get too near them with our candles could easily have damaged the natural progression of that growth. We were warned to wear sturdy, water-resistant shoes – there is indeed standing water in many places along the path. We were warned to wear warm clothes, as the cave does not get above 60 degrees – ever.
John coached us in a pre-ritual workshop in the chants for the ritual. This, in itself, was a challenge; getting about 40 people to stay together in a multi-part chant in one sitting is only a hair's breadth away from its own miracle. The addition of drums turned out to be miracle's catalyst.
That evening, we processed to the cave, carrying our candles and our jackets, in over 80-degree heat, with 75% humidity (well, it felt like it anyway) and increasing cloud cover. Quickly shrugging into those jackets on entry, we made our way down the lit pathway to the sound of water trickling down the cave walls, chanting as best we could as we walked. Down and over, down, over again and down some more, ending up in a room that had once been a reservoir of the water that was flowing into the cave. With gravel under our feet and our breath condensing in front of us, we gathered.
There was no need for a microphone; the merest whisper could be heard across the cavern. Yet even the children in attendance seemed to sense that this was a time to stay close to their own mothers, and to watch and simply experience. Our candles were lit. The electric lights were extinguished.
There was no need to cast a circle; how could we define sacred space better than the walls of the cave?
Well, how could They not show up with that kind of an invitation? With a few words for our waiting ears, She crowned the Horned One as her True Consort; Her partner in maintaining the cycle of birth, life, death and rebirth.
Well, things got wrapped up after that, and we picked our way back up the pathway to the entry of the cave, to be greeted by a great cascade of rainwater flowing down the steps – that cloud cover had hit its saturation point and dumped about a half-inch of rain while we were in the cave.
But did that stop us from lighting our vigil fire and watching for the sunrise of Midsummer's Day? Not even close!
Awe: noun - an overwhelming feeling of reverence, admiration, fear, etc., produced by that which is grand, sublime, extremely powerful, or the like.
Awesome: This Ritual! Thank you, John!
So you see, as your May Queen, I can hereby certify that the Wheel of the Year has, indeed, turned another 45 degrees. We are well and truly headed for the First Harvest of Lammas!
Lovingly submitted,
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As the marketing manager for Bridgeline Digital, a content management software company, Ryan Hadfield's primary function is to generate leads and ensure that customers are making the most of the iAPPS platform. "While lead acquisition is the heart of what I do, I love nurturing current customers and prospects with weekly segmented email campaigns that include white papers, ebooks, and other forms of thought leadership," he says.
Oct 27, 2006
Open source enterprise portal packages are seeing substantial uptake in the marketplace, but vary substantially in features and usability, and tend to target a limited set of simple scenarios, according to the latest semi-annual release of the "Enterprise Portals Report" from independent analyst firm, CMS Watch. According to the report, with the growth of open-source Java application servers, CMS Watch has found prospective portal customers taking a longer look at open source portals as well. Those customers are finding that open source alternatives can provide an acceptable platform for simple standards-compliant portlets, but may not yet be capable for more complex transactional, process-oriented scenarios. A new "Open Source Edition" compares 5 open source portal vendors head to head: eXo, Jetspeed, JBoss, Liferay, and Plone. Pricing begins at $925 for the entire report or $350 for individual vendor chapters.
Other Report findings include: open source portal packages tend to excel at scenarios emphasizing web application development and simpler informational portals. They tend not to fit well for more complex, transactional, or process-oriented portals and also offer less in the way of pre-packaged integration capabilities; all the major open source portal platforms are based on Java, with the exception of Plone, a Python-based alternative. There are no significant Microsoft-based open source portal packages to challenge Office SharePoint; community size and vibrancy varies substantially among open source portal projects; and Sun is in the midst of releasing its portal offering into open source. Sun's portal is now free of charge, but not all of the source code has been made available yet. The new Edition of the Enterprise Portals Report provides 8- to 16-page comparative product surveys of 15 enterprise portal products as well as information about 6 other packages across 3 product categories. The Report is available for purchase online.