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Immunonegative "null cell" adenomas and gonadotropin (Gn) subunit (SUs) immunopositive adenomas share frequent expression of multiple transcription factors.
ABSTRACT The differentiation of pituitary cells and human pituitary adenomas follow three cell lineages: GH-PRL-TSH, ACTH, and FSH/LH, which are regulated by a combination of various transcription factors and co-factors. We have used RT-PCR and immunohistochemistry to show that immunonegative, "null cell" adenomas are equipped with multiple transcription factors and co-factors. The "null cell" adenomas showed similar frequencies of transcription factors as did the gonadotropin subunit (GnSU)-positive adenomas, with the exception that there were fewer instances of SF1 in the former. We speculate, therefore, that null cell adenomas and GnSU-positive adenomas share common molecular mechanisms in functional differentiation, even though the former do not produce hormones. From the high frequency of various transcription factors, we also speculate that both null cell adenomas and GnSU-positive adenomas are derived from "committed" pituitary progenitor stem cells. The questions, why a certain proportion of these pituitary tumor groups lack hormone production and why they are molecularly more committed to Gn transcription, remain to be further investigated.
Article: ACTH and α-Subunit are Co-expressed in Rare Human Pituitary Corticotroph Cell Adenomas Proposed to Originate from ACTH-Committed Early Pituitary Progenitor Cells[Show abstract] [Hide abstract]
ABSTRACT: The functional differentiation of pituitary cells and adenomas follows the combination of transcription factors and co-factors in three cell lineages [growth hormone-prolactin-thyroid-stimulating hormone lineage, adrenocorticotrophic hormone (ACTH)/pro-opiomelanocortin (POMC) lineage, and follicular stimulating hormone (FSH)/luteinizing hormone (LH) lineage], which include Pit-1, GATA-2, SF-1, NeuroD1/beta2, Tpit, ERalpha, and others. Only rarely are hormones from different lineages co-expressed in the same adenoma cells. Most corticotroph cell adenomas belonging to the ACTH/POMC lineage are mono-hormonal. In our study of 89 corticotroph cell adenomas, 5 cases expressed both ACTH and alpha-subunit; these adenomas did not express any other anterior pituitary hormones or subunits. To clarify the mechanism involved, we studied the transcription factors that regulate pituitary cell differentiation. NeuroD1 and T-pit, markers of the ACTH/POMC lineage, and SF-1 and DAX-1, related to the LH/FSH cell lineage were expressed in all cases. GATA2, a synergistic factor in the gonadotroph cell lineage with SF-1, was also expressed in three of five cases. As ACTH and alpha-subunit are the earliest hormones to appear during development, we speculate that these particular adenomas are derived from committed ACTH progenitor cells. The molecular process governing functional differentiation of these adenomas requires further investigation.Endocrine Pathology 02/2008; 19(1):17-26. DOI:10.1007/s12022-008-9014-6 · 1.76 Impact Factor


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In the days leading up to a big conference, like Catapult 2014, in addition to thinking about your wardrobe, you should be thinking about your networking strategy. Whether you are a long-time legal professional, or a law student hoping to connect with potential employers, getting to know as many people as possible is always a good idea.
You never know who you are going to meet who is going to be able to help you in your career down the line, so it's important to go in with an open mind and a willingness to meet and engage your colleagues throughout the day. A successful conference is one where you leave with a handful of business cards and some real connections – that is, people you can contact after the conference and invite to coffee or lunch.
And that brings us to our fashion topic of the day – what to wear to those post-conference networking opportunities that will inevitably result from having attended the conference. Of course, your attire choice will inevitably depend on the type of meeting or networking opportunity that comes up, but we'll try to cover the basic scenarios.
In the event of a formal meeting, whether with a potential employer or a mentor in the community who you have solicited to assist you in some way in your career, err on the side of caution and wear a suit or business casual attire (this can sometimes depend on the setting – if they've asked you to meet in their office, a suit is appropriate; if you are meeting outside of the office for a coffee or a quick bite, business casual is likely appropriate). Often in these settings, a casual get together can turn into an impropmtu tour of the person's office, or an introduction to several of his or her colleagues. You'll want to look your best and feel your best, so as to impress anyone you may meet.
Oftentimes, connecting with someone post-conference is a mutually beneficial endeavor, where the objective is to explore ways you might be able to work together. If you have scheduled post-conference meetings of this sort, dress nicely and professionally (in the legal profession, optimizing the impression you make through your attire and demeanor is always a good idea) but opt for something comfortable that shows who you are. A great winter dress or slacks and a blazer for men is a reliable go-to when you are trying to make a good impression while also being yourself.
The best part about an in-depth, day long conference like Catapult is that you're bound to make friends, many who may be friends for life. These are going to be some of the most important connections you can make, not only because of the potential to help one another down the line, but because, in a profession like ours, the more people you have supporting you, the better. For a meeting that centers on developing a friendship, take it out of the business context entirely, including with your wardrobe. Jeans and a t-shirt, or whatever you might wear when you're hanging out with friends, is perfectly appropriate.
The most important take away here is to be proactive about meeting all sorts of people when you attend a legal conference, from potential employers and colleagues, to life-long friends. And with each connection, be sure to pursue follow up meetings to keep the connections flourishing, and consider the narrative you want to tell through your attire – your first opportunity to make a great impression.
Want more from House of Marbury? Click here for daily fashion and style advice for lawyers!
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DISCLAIMER: Because of the generality of this update, the information provided herein may not be applicable in all situations and should not be acted upon without specific legal advice based on particular situations.
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Stephen Moore will lead the Wallabies to the World Cup after the veteran was confirmed as Australian captain on Monday.
Topics: rugby-union-world-cup, rugby-union, sport, caloundra-4551, qld, australia
Talk of George Smith returning to the Wallabies came as a surprise to his new English club Wasps, but they will not stand in the champion back-rower's way if he gets a call up.
Topics: rugby-union-world-cup, rugby-union, sport, australia
Posted| Updated
Samu Kerevi is refusing to get carried away with his selection in the Wallabies' extended squad, even though coach Michael Cheika gave the bulldozing Reds centre a glowing endorsement.
Topics: rugby-union, super-rugby, rugby-union-world-cup, sport, brisbane-4000
Posted| Updated
Australia coach Michael Cheika has not closed the door on George Smith returning to the Wallabies fold for the World Cup, despite leaving the 111-Test veteran out of his 40-man squad for the start of the Rugby Championship.
Topics: rugby-union, super-rugby, rugby-union-world-cup, sport, australia
Posted| Updated
Brisbane City will open its National Rugby Championship defence with a grand final re-match against Perth Spirit at Ballymore in August to kick off the second edition of Australian rugby's third-tier competition.
Topics: super-rugby, rugby-union-world-cup, rugby-union, sport, brisbane-4000, robina-4226, rockhampton-4700, kawana-4701
World Rugby confirms five countries have expressed interest in hosting the 2023 Rugby World Cup.
Topics: sport, rugby-union, rugby-union-world-cup, france, ireland, italy, south-africa, united-states
Posted| Updated
Former All Blacks back rower Jerry Collins and his wife have died following a car accident in France.
Topics: rugby-union-world-cup, super-rugby, rugby-union, sport, france, new-zealand
Western Force number eight Ben McCalman is the second Wallabies player to secure a flexible contract allowing him to play in Japan, after agreeing to three more years in Australian rugby.
Topics: rugby-union, sport, rugby-union-world-cup, super-rugby, perth-6000, wa, australia, japan
Posted| Updated
Injured Queensland Reds hooker Saia Fainga'a remains confident he will have enough time to push his selection claims for the Wallabies' World Cup squad.
Topics: rugby-union, super-rugby, rugby-union-world-cup, sport, brisbane-4000
Posted| Updated
Wallabies hooker Saia Fainga'a believes rugby sevens can serve as a key pathway to see more Indigenous Australians play at the Test and Super Rugby level.
Topics: super-rugby, rugby-7, rugby-union, sport, rugby-union-world-cup, indigenous-aboriginal-and-torres-strait-islander, community-and-society, indigenous-other-peoples, brisbane-4000
Posted| Updated
Experienced prop Ben Alexander has signed a new one-year deal to stay at the Brumbies until the end of the 2016 Super Rugby season.
Topics: sport, rugby-union, super-rugby, rugby-union-world-cup, canberra-2600, act, australia
Rugby league convert Sam Burgess was named in hosts England's 50-man training squad announced Wednesday for this year's World Cup.
Topics: rugby-union-world-cup, rugby-union, sport, england
Posted| Updated
Reds coach Richard Graham believes there is still time for Quade Cooper to press his claims for World Cup selection, despite his return from injury being put on ice for another week.
Topics: rugby-union, super-rugby, sport, rugby-union-world-cup, brisbane-4000
Posted| Updated
Waratahs flyer Taqele Naiyaravoro will come into Wallabies calculations after being granted sport visa, says Michael Cheika.
Topics: rugby-union-world-cup, super-rugby, rugby-union, sport, sydney-2000, nsw, australia
Posted| Updated
Former England skipper Lawrence Dallaglio says overseas-based players like Steffon Armitage should forget about Rugby World Cup selection.
Topics: sport, rugby-union, rugby-union-world-cup, england, france
The Wallabies will play a Rugby World Cup warm-up game against the USA on September 5, their first Test in the United States for almost 40 years.
Topics: rugby-union, sport, rugby-union-world-cup, united-states, australia
Western Force coach Michael Foley says his captain, Matt Hodgson, should be in the Wallabies squad for this year's Rugby World Cup.
Topics: rugby-union-world-cup, super-rugby, rugby-union, sport, perth-6000, wa, australia
Posted| Updated
Quade Cooper's hopes of World Cup selection have received a boost with the Queensland Reds expecting their star playmaker to return from injury earlier than expected.
Topics: super-rugby, rugby-union, sport, rugby-union-world-cup, brisbane-4000
Posted| Updated
New Zealand rugby chiefs have no plans to relax rules to allow overseas-based players to be eligible for All Black selection.
Topics: sport, rugby-union, rugby-union-world-cup, new-zealand, australia
Posted| Updated
The new Wallabies eligibility rules open the door for overseas stars such as Matt Giteau to play in the World Cup.
Topics: super-rugby, rugby-union, rugby-union-world-cup, sport, australia, france
Topics: rugby-union, rugby-union-world-cup, sport, new-zealand
Posted| Updated
The Wallabies have fallen to sixth in the world rankings ahead of the Rugby World Cup.
Topics: rugby-union-world-cup, rugby-union, sport, australia
Stephen Larkham has been appointed as a Wallabies assistant coach to Michael Cheika for the 2015 Test season.
Topics: rugby-union, sport, super-rugby, rugby-union-world-cup, canberra-2600, sydney-2000
Posted| Updated
Sekope Kepu and Nic White are the latest Wallabies to announce they will leave Australian rugby.
Topics: rugby-union, super-rugby, rugby-union-world-cup, sport, sydney-2000, canberra-2600
Waratahs and Wallabies half-back Nick Phipps signs contract extension to keep him in Australia until end of 2017.
Topics: sport, rugby-union, rugby-union-world-cup, sydney-2000, nsw, australia


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For some it was merely a day out of class. For others it was their first step on the path to a career. Last Wednesday, 46 area students joined a comprehensive tour of manufacturing facilities in Greenville. In a series of groups, students were given an intimate look at Greenville Tool & Die Co., Federal-Mogul Corp., Clarion Technologies, Aggressive Tooling Inc. and West MI Compounding.
Christmas may be months away, but ask a faculty member at Carson City-Crystal Area Schools, and you'll hear that gifts appear to be arriving every day.
These gifts, however, don't come in a box wrapped in colorful paper and topped off with a pretty bow.
With its roots firmly grounded in a small community that prides itself on both a history of hard work and quality manufacturing, Granco Clark continues to shine as a beacon of success in its industry. Locally, Granco Clark is a company within the extrusion industry that employs a workforce of about 105 dedicated skilled workers in a variety of positions.
The Wheatland Music Festival always draws a crowd, and this year it was a sellout one.
The 42nd annual festival took place Friday through Sunday near Remus, boasting an audience of more than 10,000 people.
A lifelong resident of Michigan, Rep. Rick Outman, R-Six Lakes, is well aware of how important the surrounding Great Lakes are to every resident of the "mitten state."
From drinking water to recreation, and freighters shipping goods to the state's vast fishing industry, the priority of protecting the state's invaluable natural resource is always a concern for legislators.
Howard City's annual celebration of autumn will return once again with events old and new. The 13th annual Howard City Harvest Festival will take place all day Saturday in downtown Howard City.
Organizers put a great deal of work into this year's Potato Festival. This past weekend, that effort paid off in spades as hundreds of locals and visitors alike gathered to honor the noble tuber, a staple of the area's economy for decades.


text: My boyfriend and I spent one night in Bangkok before heading South. We wanted to experience Khaosan Road but stay in a hotel rather than a hostel. The Khaosan Park Resort was a good spot for one or two nights to be able to conveniently go out on Khaosan and then have a basic, private and clean room to put... More


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Intel Driver Update Utility
editor's review
Intel Driver Update Utility is an ActiveX / Java component that provides access to an update scanner for Intel drivers.
Although there are many alternatives that can search for outdated drivers on your computer, most often, these are not free of charge and sometimes they fail to detect the existence of updates. This is good enough reason to perform such operations using a utility developed by the manufacturer itself, if possible.
Intel does provide such a service that scans the system, revealing the updates that are relevant to your computer, allowing you to download and install them on the spot.
The service uses an online approach, which can be evaluated in two different ways. Intel's support page located here offers the possibility to scan the system right away, attempting to install an ActiveX widget in order to make the detection engine viable.
The second approach is aimed at Internet Explorer users who cannot start the engine for various reasons. The recommended solution in this case is to use the ActiveX component that you can install manually in order to enable the browser to support the service.
This ActiveX component is called System Requirements Lab, generally used for identifying the compatibility of the components on your system with various programs and games. In this case, it's used to provide access to Intel's scanner and to install drivers that are compatible with your hardware.
In a nutshell, you need to install Intel Driver Update Utility, the ActiveX version, when your Internet Explorer can't manage to launch the Intel driver service properly. Deploying this package will help you to run driver scans properly.
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This is a video about the IAU definition of a planet. Learners will watch 3D animation designed to illustrate the history behind the discussion defining the question, what is a planet?, and to outline some of the traits that may be associated with... (View More) the definition of a planet. (View Less)
Materials Cost: Free
This is an activity about the concept of direct versus indirect sunlight. Learners construct and use a sun angle analyzer to investigate the effect of angle on area illuminated. The fraction of light on each square of the analyzer is then calculated... (View More) and compared. A discussion at the end relates the results to the amount of sunlight falling on different parts of the Earth and the effect this has on temperature and seasons. Reprinted with permission from the Great Explorations in Math and Science (GEMS). (View Less)
In this lesson, students create a fictional narrative on the beginning of time. They use their scientific knowledge of the Big Bang Theory and go back into time to when it occurred so they can make observations about it. Students can select from... (View More) four options for creating a final product that demonstrates their learning using the RAFT (Role, Audience, Format, and Topic) method. This lesson is from the Cosmic Times teachers guide and is intended to be used in conjunction with the 1955 Cosmic Times poster. (View Less)
Materials Cost: 1 cent - $1 per group of students
Students are introduced to the basic properties, behavior and detection of black holes through a brief discussion of common conceptions and misconceptions of these exciting objects. They "act out" a way black holes might be detected through their... (View More) interaction with other objects. In this activity, girls represent binary star systems in pairs, walking slowly around one another in a darkened room with each pair holding loops of wire to simulate the gravitational interaction. Most of the students are wearing glow-in-the-dark headbands to simulate stars, some are without headbands to represent black holes, and a small set of the black holes have flashlights to simulate X-ray emission. This activity is part of a series that has been designed specifically for use with Girl Scouts, but the activities can be used in other settings. Most of the materials are inexpensive or easily found. It is recommended that a leader with astronomy knowledge lead the activities, or at least be available to answer questions, whenever possible. (View Less)
Materials Cost: $1 - $5 per group of students
This activity provides a visual example of convection in fluids. Students will record their predictions and observations on diagrams of the experimental set-up showing convection currents. Materials required include hot and cold colored water,... (View More) thermometers, stopwatch, and index cards. This activity is part of the MY NASA DATA Scientist Tracking Network unit, designed to provide practice in accessing and using authentic satellite data. (View Less)
Materials Cost: Free
This series of curriculum support materials and classroom activities explores how our understanding of the nature of the universe has changed during the past 100 years. Students examine the process of science through the stories of the people and... (View More) the discoveries that caused our understanding to evolve from a static universe to a universe whose expansion is accelerating. The series illustrates the nature of science by tracing the process of discovery from the confirmation of Einstein's theory of gravity, to Hubble's evidence for the expanding universe, to the detection of the microwave background, and finally to the discovery of dark energy. The series includes six posters, each resembling the front page of a newspaper from a particular time in this history with articles describing the discoveries. Each poster is accompanied by an online teacher guide and 4-5 downloadable, inquiry-based lessons. Downloadable newsletter versions of the poster are available for individual student use, with three editions for different reading levels (Early Edition for 7-8 grade readers, Home Edition for 9-10 grade readers, and Late Edition for 11-12 grade readers). Lesson plans can be found by following the link from Teacher Resources to Curriculum Tools to Sortable Table of the Lessons. (View Less)
Materials Cost: Free
In this lesson, students examine the idea of inflation in the Universe using rising raisin bread dough as a model for universal expansion. Students will read the Cosmic Times 1993 edition and use two articles: Pancake or Oatmeal Universe - What's... (View More) for Breakfast and Inflation in the Universe to help them make observations. The students will observe a bowl of oatmeal to explain the lumpiness and smoothness of the universe. Then the students will use raisin bread to describe how the universe went through a period of inflation to expand into its current form today. This lesson is part of the Cosmic Times teacher guide and is intended to be used in conjunction with the 1993 Cosmic Times Poster. (View Less)
Materials Cost: $1 - $5 per group of students
In this lesson, students simulate an experiment in which the discovery of dark energy can be made by plotting modern supernova distances on a Hubble Diagram. Data is provided in an Excel spreadsheet (see related resources). In order to complete this... (View More) activity, students should be familiar with Hubble's Law and the concepts of absolute luminosity, apparent luminosity, and Doppler shift (particularly redshift). This activity can be done using either a computer graphing program or manually with graph paper. This lesson is part of the "Cosmic Times" teacher's guide and is intended to be used in conjunction with the 2006 Cosmic Times Poster. (View Less)
Materials Cost: Free
This is an activity about mission planning. Learners will use the roles of a navigation team, spacecraft, comet, Earth, and Sun to simulate how mission planners design a spacecraft/comet rendezvous. This activity requires at least four active... (View More) participants and a large open space. Includes mathematics extensions. (View Less)
Materials Cost: $5 - $10 per group of students
In this lesson plan, students participate in a hands-on activity using a plastic bottle and other simple ingredients to learn the three factors required for cloud formation. Detailed Procedure and materials, vocabulary linked to an on-line glossary,... (View More) and teacher notes are provided. This activity is related to the NASA CERES Students Cloud Observations Online (S'COOL) project. (View Less)
Materials Cost: 1 cent - $1 per group of students


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January 28, 2013
I'm a critical and music&arts lover and 100% - addicted to music. Love singing and playing some instruments (nothing professional) such as guitar, drums, piano, harmonica. I'm eclectic but what I caches my attention is mixing different styles.
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Photo Coverage: Sierra Boggess, Julian Ovenden & The New York Pops Rehearse for Tonight's Season Opener
by Stephen Sorokoff - Oct 9, 2015
Tonight, October 9, 2015 at 8:00PM, The New York Pops, led by Music Director Steven Reineke, opens its 33rd season atCarnegie Hall's Stern Auditorium/Perelman Stage with My Favorite Things: The Songs of Rodgers and Hammerstein. BroadwayWorld brings you a look inside rehearsal below! (more...)
WAKE UP with BWW 10/9/2015 - NY Pops, COMEDY OF ERRORS, KING CHARLES III and More!
by Jessica Khan - Oct 9, 2015
Good morning, BroadwayWorld! Because we know all our readers eat, sleep and breathe Broadway, what could be better than waking up to it? This weekend's big news: The NY Pops launches its 2015-16 season with two stage greats, COMEDY OF ERRORS goes on tour and KING CHARLES IIIÂ arrives in New York! (more...)
Sierra Boggess and Julian Ovenden Star in New York Pops' Season Opener Tonight
by BWW News Desk - Oct 9, 2015
Tonight, October 9, 2015 at 8:00PM, The New York Pops, led by Music Director Steven Reineke, opens its 33rd season at Carnegie Hall's Stern Auditorium/Perelman Stage with My Favorite Things: The Songs of Rodgers and Hammerstein. (more...)
FROM PAGE TO STAGE Sets Stars
by BWW News Desk - Oct 9, 2015
Aria Entertainment today announces the casts and creative teams for the eight shows in the third From Page To Stage season of new musicals, running from Monday 26 October to Saturday 21 November. (more...)
Adelphi University's BEST OF BROADWAY: GOLD, RUBIES AND PEARLS Set for 10/17-18
by BWW News Desk - Oct 9, 2015
The Department of Music at Adelphi University is proud to present the latest installment of its Best of Broadway concerts titled Gold, Rubies and Pearls celebrating the anniversaries of many Broadway classics. The show is directed by Adelphi adjuncts Erin Quill, from the original Broadway company of the Tony award-winning Avenue Q, and Jad Bernardo, the award-winning musical director. The program will take place on Saturday, October 17, at 8:00 p.m. and Sunday, October 18, at 4:00 p.m. at the Adelphi University Performing Arts Center, Concert Hall, 1 South Avenue, Garden City, New York. This performance is part of the Poole Family Broadway Series which is generously sponsored by Mary Jane and Thomas Poole. (more...)
Sheffield Theatres' SHOW BOAT Announces Extension
by BWW News Desk - Oct 9, 2015
Sheffield Theatres' Artistic Director Daniel Evans today announces, due to popular demand, a one-week extension for his new production of Jerome Kern and Oscar Hammerstein II's musical Show Boat. The production which opens on 16 December 2015, with previews from 10 December, will now run until 23 January 2016. (more...)
BWW Spoiler Alert!: UNDATEABLE's LIVE Season Premiere LIVE Recap and Commentary
by Matt Tamanini - Oct 9, 2015
I've only watched one episode of NBC's Friday night sitcom UNDATEABLE, so I am not going to claim to be an expert on the deep, emotional lives of Danny, Justin, and the rest of their undateable friends. However, that one episode that I watched was an episode that was broadcast live last May. Yes the show was sucked me in with an obvious, attention-grabbing gimmick, but it was a gimmick that I found to be very interesting. Not only did the idea call back to the early days of television, where, by the constraints of technology, all shows had to be broadcast live, but it also opened up the door for legitimate comedic improv, that you can't see anywhere else on TV. Also, as someone who loves theatre as much as I love TV, this brought a new form of live entertainment into people's homes. (more...)
Jake Robards to Lead NYC Premiere of PROMISING at Beckett Theatre
by BWW News Desk - Oct 8, 2015
InProximity Theatre Company will present the NYC premiere of PROMISING, written by Michelle Elliott and directed by Terry Berliner. PROMISING begins performances on Saturday, November 14 for a limited engagement through Saturday, December 5. Opening Night is Wednesday, November 18 at 8 PM. The performance schedule is Tuesday at 7 PM; Wednesday - Friday at 8 PM; Saturday at 2 PM &  8 PM; Sunday at 3 PM. Please note, there are added Wednesday matinee performances on November 25 and December 2 at 2 PM; there is no performance on Thanksgiving (Thursday, November 26). Performances are at the Beckett Theatre on Theatre Row (410 W 42nd Street, between 9th and Dyer). Tickets are $25 and are available by calling Telecharge at 212-239-6200 or online via telecharge.com. (more...)
THE BANDSTAND Begins Starry World Premiere at Paper Mill Playhouse Tonight
by BWW News Desk - Oct 8, 2015
Paper Mill Playhouse opens its 2015-2016 season with the world premiere musical THE BANDSTAND. Performances begin tonight, October 8. (more...)
Billie Wildrick & Dieter Bierbrauer to Lead THE SOUND OF MUSIC at Ordway
by BWW News Desk - Oct 8, 2015
Ordway Center for the Performing Arts today announced casting for the roles of Maria, Captain von Trapp and the von Trapp children for its upcoming holiday production of The Sound of Music, running Dec. 10, 2015-Jan. 2, 2016. Tickets for the Ordway produced family classic start at $37 and can be purchased online at www.ordway.org, by phone at 651-224-4222 or in-person at the Ordway ticket office. (more...)
BWW Interview: 6 Questions & a Plug with BROADWAY SONGBOOK OF THE 70s' Randy Schmeling
by Kristen Hirsch Montag - Oct 8, 2015
James Rocco and the Ordway's BROADWAY SONGBOOK® series have been seen in this space many times before. Usually, the shows are a virtual musical theatre master class with a local slate of triple threats. This time is no exception but THE 70s SONGBOOK is a slightly different show, just as the decade was a slightly different musical theatre experience. Cue the Disco beat. (Or maybe not!) (more...)
Photo Flash: Well-Strung Performs POPssical to Sold-Out Crowd at Feinstein's/54 Below
by BWW News Desk - Oct 8, 2015
Last night, October 7, Well-Strung plucked the heartstrings of the audience at Feinstein's/54 Below performing a concert celebrating the release of their 2nd studio album POPssical. Scroll down for photos from the concert! (more...)
Julian Ovenden to Lead ITV's Live THE SOUND OF MUSIC This Christmas
by Jessica Khan - Oct 8, 2015
ITV is putting on its own live version of Rodgers and Hammerstein's The Sound of Music this Christmas, and, according to the Daily Mail, Julian Ovenden will star as 'Captain Von Trapp'. (more...)
CINDERELLA & Saenger Parter with Cinderella Project for Dress Donations
by BWW News Desk - Oct 7, 2015
The Cinderella Project, Saenger Theatre and the company of Rodgers + Hammerstein's CINDERELLA are pleased to announce that now through Tuesday, Oct. 27, donations of costume jewelry, girls' princess dresses and teen prom dresses for girls in need will be accepted at the following locations: (more...)
Sarah Stiles, Jake Epstein, Emily Padgett and More Join NAMT's 2015 FESTIVAL OF NEW MUSICALS; Final Cast Set!
by BWW News Desk - Oct 7, 2015
National Alliance for Musical Theatre has announced final casting for the 27th ANNUAL FESTIVAL OF NEW MUSICALS, which takes place on Thursday, October 15 and Friday, October 16 at New World Stages (340 West 50th Street, between 8th and 9th Avenues). (more...)
WAKE UP with BWW 10/7/2015 - Tim Minchin Hits 40 and More!
by Jessica Khan - Oct 7, 2015
Good morning, BroadwayWorld! Because we know all our readers eat, sleep and breathe Broadway, what could be better than waking up to it? Today's big news: It's MATILDA composer/lyricist Tim Minchin's 40th birthday! Tweet him your best wishes @timminchin! (more...)
A Time to Shine Youth Cabaret Set for This Saturday at The Triad
by BWW News Desk - Oct 7, 2015
A Time To Shine Youth Cabaret presents teen and young adult performers from Broadway, film and TV this Saturday, October 10 at 9:30pm (doors open at 9pm) at Stage 72 @ The Triad, 158 W. 72nd Street, bet. Broadway & Columbus Ave. (more...)
VIDEO: THE WIZ LIVE! Shares First Look at Choreography on Stilts!
by TV News Desk - Oct 7, 2015
Footgage from the first week of rehearsals for NBC's THE WIZ LIVE! has been shared on the show's Instagram, including actors walking on stilts! (more...)
BWW TV: Follow THE WIZ LIVE's Shanice Williams from Audition to First Table Read
by BroadwayWorld TV - Oct 7, 2015
NBC has shared a special video entitled 'Live A Day In The Life With Shanice Williams' which chronicles the 19-year-old star of THE WIZ LIVE! from audition day to first table read. (more...)
Photo: Twitter Tease from THE WIZ LIVE's First Week of Rehearsals
by TV News Desk - Oct 7, 2015
As excitement builds for the live broadcast of NBC's THE WIZ LIVE! on Thursday December 3rd, check out images which were part of a twitter tease from the first days of rehearsal. (more...)
Tickets to David Bowie & Enda Walsh's LAZARUS at NYTW on Sale Today
by BWW News Desk - Oct 7, 2015
Tickets for LAZARUS, the second production of the New York Theatre Workshop (NYTW) (Artistic Director James C. Nicola and Managing Director Jeremy Blocker) 2015/16 Season, will go on sale today beginning at 12pm EST. Single tickets for LAZARUS are $95. A limited number of $25 CheapTix will be available on a first-come, first-served basis for the first two performances. Tickets and membership packages can be purchased by visiting www.nytw.org or by calling 212-460-5475 (Monday-Friday, noon-6pm) or visiting the NYTW Box Office (79 E. 4th Street New York, NY 10003). (more...)
TYD & WEILL Sings Kurt Weill to Life at Stellenbosch's Drostdy Theatre
by BWW News Desk - Oct 7, 2015
The legendary music of Kurt Weill will fill the auditorium of the Drostdy Theatre in Stellenbosch when TYD & WEILL, which premiered at the US Woordfees in March, makes its bow there this October. (more...)
WAKE UP with BWW 10/6/2015 - OLD TIMES, ALLEGIANCE, BULLETS and More!
by Jessica Khan - Oct 6, 2015
Good morning, BroadwayWorld! Because we know all our readers eat, sleep and breathe Broadway, what could be better than waking up to it? Today's big news: OLD TIMES opens on Broadway, ALLEGIANCE starts performances and BULLETS OVER BROADWAY heads out on tour! (more...)
THE BRIDGES OF MADISON COUNTY To Stage First International Production; Announces Full Cast
by BWW News Desk - Oct 6, 2015
Atlantis Theatrical Entertainment Group (ATEG) is proud to announce the full cast for the first international production of the Tony Award-winning musical THE BRIDGES OF MADISON COUNTY, which runs from November 20 - December 6 at the Carlos P. Romulo Auditorium, RCBC Plaza, Makati City. (more...)
STANDING TALL Reading to Bring 9/11-Inspired Emails, Journals and Creative Writing to the Stage, 11/7
by BWW News Desk - Oct 5, 2015
An adaptation of the book STANDING TALL - the emails, journals and creative writings of 9/11 is being presented November 7th at 7:00 PM at ArtNY Bruce Mitchell Theatre, 520 Eighth Avenue, 3rd Floor produced by FACT Theatre Company. (more...)
Twitter Watch: Rehearsals for NBC's THE WIZ LIVE Begin Today!
by TV News Desk - Oct 5, 2015
Harvey Fierstein took to Twitter yesterday to share the exciting news that rehearsals for NBC's highly anticipated broadcast of THE WIZ LIVE! will get underway today. (more...)
Stephanie Mills on Reprising Role of Aunt Em for THE WIZ Broadway Revival: 'In a Heartbeat'
by TV News Desk - Oct 5, 2015
Mills is 'starstruck' by her fellow castmates, including Queen Latifah (the Wiz), Mary J. Blige (Evilene), Uzo Aduba (Glinda) and Amber Riley (the GOOD WITCH of the North.) (more...)
TWITTER WATCH: More Updates From THE WIZ LIVE!'s First Rehearsal
by Michael Dale - Oct 5, 2015
Enjoy more Tweets and photos as the company gets ready for the December 3rd telecast. (more...)
TWITTER WATCH: Photo From THE WIZ LIVE! First Day of Rehearsals, Stephanie Mills Has 'Cast In Tears'
by Michael Dale - Oct 5, 2015
Producer Neil Meron posts a pic of the company getting to work and reports on their reaction to hearing Stephanie Mills sing. (more...)
Regional Roundup: Top 10 Stories This Week Around the Broadway World - 10/2; DESTINY OF DESIRE in DC, SOUND OF MUSIC Tour in LA and More!
by BWW Special Coverage - Oct 2, 2015
This week, we go around our Broadway World to feature stories in Washington DC, Los Angeles, Spain and more. Check out our top 10 stories around our Broadway World below, which include Arena Stage's DESTINY OF DESIRE, The Sound of Music National Tour in LA, and BLOOD BROTHERS in Chicago, just to name a few. (more...)
STAGE TUBE: Go Behind the Scenes of KINGS OF BROADWAY Concert Photo Shoot!
by BWW News Desk - Oct 2, 2015
A spectacular concert Kings Of Broadway which celebrates the music of legendary Broadway composers Jerry Herman, Stephen Sondheim and Jule Styne will be performed for one night only  at The Palace Theatre, London on Sunday November 29. (more...)
WAKE UP with BWW 10/2/2015 - SYLVIA Brings Canine Companionship to Broadway!
by Jessica Khan - Oct 2, 2015
Good morning, BroadwayWorld! Because we know all our readers eat, sleep and breathe Broadway, what could be better than waking up to it? This weekend's big news: SYLVIA starts on Broadway tonight, and Sunday is your last chance to see Sydney Lucas in FUN HOME! (more...)
THIS WEEK IN PICTURES: September 26- October 2
by Nora Dominick - Oct 2, 2015
Watching ELSIE FEST videos on a loop? Still trying to win the #Ham4Ham lottery? Didn't have time to check in on your favorite Broadway stars? Well don't worry BroadwayWorld has rounded up some of the biggest stories from this week from Broadway and beyond with BroadwayWorld's 'This Week in Pictures.' (more...)
BWW Review: New York Pops, Sierra Boggess, Julian Ovenden in MY FAVORITE THINGS: THE SONGS OF RODGERS AND HAMMERSTEIN
by Michael Dale - Oct 13, 2015
A grand Carnegie Hall concert featuring selections from the team's 11 collaborations. (more...)
Adelaide Repertory Theatre to Present ONLY AN ORPHAN GIRL
by BWW News Desk - Oct 12, 2015
The Adelaide Repertory Theatre is serving up 'ham' early this Christmas, with hilariously over the top music hall show and melodrama Only an Orphan Girl set for a special end-of-year season at the Arts Theatre. (more...)
BWW Review: CRAZY EX-GIRLFRIEND, Starring Rachel Bloom & Santino Fontana, is Subversive Musical Joy
by Matt Tamanini - Oct 12, 2015
Theatre fans have had a tenuous relationship with television musicals over the past few years. Whether it was the casual dismissal of GLEE after its strong first season, the hate-watching of SMASH, or the mixed-reactions to The Sound of Music and PETER PAN LIVE!, theatre fans have set a pretty high bar for programs that look to bring musical programming from stage to screen. With THE WIZ LIVE! and GREASE LIVE! still months away, a new musical TV show premieres tonight starring Tony-nominee Santino Fontana and Obie Award-winner Donna Lynne Champlin. CRAZY EX-GIRLFRIEND, the joyfully kooky comedy that debuts on The CW tonight at 8:00pm ET, was created by Upright Citizen's Brigade member Rachel Bloom, who also stars as the titular crazy character. (more...)
BWW Interview: Laura Osnes Journeys Back in Time in Paper Mill's THE BANDSTAND
by Caryn Robbins - Oct 12, 2015
Today, Osnes speaks exclusively to BWW about her journey back in time in the exciting new musical BANDSTAND. (more...)
Photo Coverage: Sierra Boggess and Julian Ovenden Join The New York Pops for MY FAVORITE THINGS
by Genevieve Rafter Keddy - Oct 12, 2015
On October 9, The New York Pops, led by Music Director Steven Reineke, opened its 33rd season at Carnegie Hall's Stern Auditorium/Perelman Stage with My Favorite Things: The Songs of Rodgers and Hammerstein. The concert honored the duo's timeless work, which has captured the hearts of every generation of music lovers, and featured guest artists Sierra Boggess and Julian Ovenden (who replaced the previously announced Steven Pasquale), alongside Judith Clurman's Essential Voices USA. Check out photos from the event below! (more...)
Photo Coverage: Go Backstage with Sierra Boggess and Julian Ovenden at The New York Pops
by Genevieve Rafter Keddy - Oct 12, 2015
On October 9, The New York Pops, led by Music Director Steven Reineke, opened its 33rd season at Carnegie Hall's Stern Auditorium/Perelman Stage with My Favorite Things: The Songs of Rodgers and Hammerstein. The concert honored the duo's timeless work, which has captured the hearts of every generation of music lovers, and featured guest artists Sierra Boggess and Julian Ovenden (who replaced the previously announced Steven Pasquale), alongside Judith Clurman's Essential Voices USA. Below, BroadwayWorld takes you backstage with the stars! (more...)
Commercial Theater Institute to Host Winter 14-Week Program for Producers, Managers; Deadline 12/7
by BWW News Desk - Oct 12, 2015
The Commercial Theater Institute announced admission details and deadlines for the upcoming Fourteen Week Program: Advanced Topics for Commercial Producers and Managers, a course which takes a comprehensive look at the many aspects of producing in the commercial theater industry. (more...)
Upcoming Non-Equity Auditions Sunday, Oct. 11
by Audition Roundup - Oct 11, 2015
Updated this week! Check out upcoming Non-Equity Auditions from Sunday, October 11, 2015 for productions in your area and around the country. (more...)
Guest Artists Announced for 2015 Rob Guest Endowment Concert
by BWW News Desk - Oct 10, 2015
The 2015 Rob Guest Endowment Grand Final Concert will be held on Monday 9 November at the Sydney Lyric Theatre. Hosted by Lucy Durack and David Campbell, guest artists performing at the concert will include musical theatre performers Rob Mills and Jemma Rix, Dirty Dancing star Mark Vincent, 2014 Rob Guest Endowment winner Joshua Robson, and cast members from Matilda and Cats. (more...)
The London Palladium Production of THE SOUND OF MUSIC to Play Adelaide
by BWW News Desk - Oct 10, 2015
Producers Andrew Lloyd Webber, David Ian, John Frost and the Really Useful Group today announced that the world's favourite musical, The Sound of Music, would come to Adelaide in 2016. (more...)
Laura Benanti Will Play NJPAC's Chase Room This November
by BWW News Desk - Oct 1, 2015
On Saturday, November 21, Tony Award winner Laura Benanti will present an evening of song - the best of the Great White Way and beyond - in the intimate Chase Room at New Jersey Performing Arts Center (1 Center Street, Newark NJ). (more...)
STAGE TUBE: Top 8! Celebrate Julie Andrews 80th Birthday With Our Favorite Performances!
by Nora Dominick - Oct 1, 2015
Happy 80th Birthday Julie Andrews! Today the cherished stage and screen veteran celebrates her 80th birthday and to celebrate her special day, BroadwayWorld has decided to to round up eight of our favorite videos from her illustrious career- one for each fantastic decade that humanity has been graced with her presence. (more...)
Photo Flash: THE SOUND OF MUSIC National Tour Celebrates Opening Night in Los Angeles; Curtain Call!
by BWW News Desk - Oct 1, 2015
A brand new production of Rodgers & Hammerstein's classic The Sound of Music launched its national tour at the Center Theatre Group / Ahmanson Theatre last night, September 30 at 8 p.m. Directed by three-time Tony Award winner Jack O'Brien, the production closes in Los Angeles on October 31, 2015, and will then tour North America for multiple seasons, playing multi-week and week-long engagements. BroadwayWorld has photos from the opening night curtain call and festivities below! (more...)
WAKE UP with BWW 10/1/2015 - Keira Knightley Onstage and More!
by Jessica Khan - Oct 1, 2015
Good morning, BroadwayWorld! Because we know all our readers eat, sleep and breathe Broadway, what could be better than waking up to it? Today's big news: Keira Knightley makes her Broadway debut, A CLOCKWORK ORANGE hits the stage and more! (more...)
BWW Review: Vibrant New SOUND OF MUSIC Opens at the Ahmanson
by Don Grigware - Oct 1, 2015
Perhaps the best known musical of all time Rodgers' and Hammerstein's The Sound of Music has remained a family favorite since the 50s. Number one, the score is to die for; secondly, the book is dramatically fulfilling with a real life family being torn asunder by the ravages of fascism. Touches of real intertwined humor add to the appeal. Under the skillful eye and wisdom of director Jack O'Brien, the new North American touring production is now at the Ahmanson through October and proves thoroughly winning. I wouldn't say there's a totally fresh perspective, but somehow touches of real humanity and love stand out, and the entire ensemble is perfectly cast. (more...)
Universal Nabs Craig Zadan & Neil Meron's IN SIGHT, Starring Joseph Gordon-Levitt
by TV News Desk - Oct 1, 2015
Universal Pictures has just picked up the psychological thriller IN SIGHT from Broadway, TV and film producing team Craig Zadan and Neil Meron. (more...)
STAGE TUBE: On This Day for 10/1/15- Julie Andrews
by Stage Tube - Oct 1, 2015
Happy Birthday, Julie Andrews! Andrews made her Broadway debut in 1954 with The Boy Friend, and rose to prominence starring in other musicals such as My Fair Lady and Camelot, and in musical films such as Mary Poppins (1964), for which she won the Academy Award for Best Actress, and The Sound of Music (1965). She has starred in films such as The Princess Diaries (2001), its sequel The Princess Diaries 2: Royal Engagement (2004), the Shrek animated films (2004-2010), and Despicable Me (2010). (more...)


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AIM Wins National Award of ExcellenceSubmitted by Melissa_Snowden on Wed, 2014-07-09 15:42
We have just been awarded Overall Excellence in Public Access in the 2014 Hometown Media competition. This marks the ninth time in 24 years that AIM has received this prestigious prize. "We are pleased and honored to win this award, which recognizes the outstanding work of our staff and volunteers," AIM executive director Paul LeValley said.


text: Our group of 6 enjoyed a luxurious stay with Serge the owner. Modern wood decor, full tile bathrooms with robes, comfortable sitting area, quiet location. After a day of bike riding, the shower felt wonderful. The property is a bit out of town so we called a taxi to get us to and from dinner. Breakfast was wonderful and there... More


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Plug Into our N.O.W. TEAMS where all the Action Is!!
N: NURTURE TEAM ACTIVITIES (Team Leader Kathy Klei): Soup Suppers & Potlucks; Bible Studies; Camping Trips. Easter/Christmas Bunches; Women's Epiphany Brunch; Men's Breakfast; Potluck Dinners; Worship Services; Visit Shut-Ins
O: OUTREACH TEAM ACTIVITIES (Team Leader Lynn Tharp): Sept. BFF BBQ; Church Cluster Events. Fund Raisers; Holiday Baskets; Monthly Missions; Pantry/Thrift Center; Prayer Requests; Website; Special Guests/Music; Yard Sales, Women's Tea
W: WITNESS TEAM ACTIVITIES (Team Leader Needed): Worship Services; Decorations; Church Sign; Christmas Tree; DYFS Gifts; Community Cross; Labyrinth; Membership Roll; Spiritual Gifts Test; Township Days; Vacation Bible School
Porchtown Church BFF (Bring Friends & Family) Open House & BBQ Oct. 3 + 4, 2015
Porchtown Zion United Methodist Church, located at 220 Porchtown Road in Franklin Township, invites the community to its annual BFF (Bring Friends & Family)
Open House Weekend October 3 + 4, 2015.
This weekend is jam-packed with activities:
Sat. Oct. 3: Our Fall Yard Sale 8 am to 2 pm at Social Hall
Sat. Oct. 3: A Special Concert with *Sigh8 7 pm at Malaga UM Church.
Sun. Oct. 4: Our BFF Worship Service/*Sigh 8 Concert at 10:30 am
Sun. Oct. 4: A Free BFF BBQ at the Social Hall 11:30 a.m. to 1 p.m. (rain or shine).
Everyone is invited as Porchtown Church celebrates more than 212 years of continuous community service! Stop by and check us out!
We always offer delicious food & wonderful fellowship!
Visit our facebook page
'Porchtown Zion United Methodist Church'
for updates and inspiration.
➣GRANDPARENT'S POTLUCK: 5 pm Sun. SEPT. 13 - Bring an item to share (made w/your grandparent's recipe). Bring your Grandparents (or their picture) and/or your Grandchildren too!
➣NEW BFF WEEKEND: YARD SALE: OCT. 3 - 8am to 2 pm
*SIGH8 CONCERT: OCT. 3 7 pm at MALAGA CHURCH
BFF SUNDAY: *SIGH8 in CONCERT at 10:30 AM WORSHIP
BFF BBQ: 11:30 am at the Social Hall!!! Fun Weekend!
➣PANTRY HOURS: Sat. Sept. 19 - 10am to noon. Contact Lisa or Joe.
Thank you for Non-Perishable Food, Monetary + Clothing donations!
Contact Lisa (856) 641-2124 if you have questions.
Please visit our Porchtown Happenings Newsletter link at left for activity details.
or call (856) 694-1983 and leave a message with callback information.


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Unless bankers change the internal culture that rewards executives and employees for financial misdeeds, a top banking regulator said Monday, they will end up forcing the government to break their companies up into smaller firms.
Alibaba, the massive Chinese e-commerce company that is the functional equivalent of Amazon, EBay, Uber, PayPal and a bunch of other companies combined, made its debut on the New York Stock Exchange this morning. It was the largest initial public offering in U.S. history, raising over $21.8 billion.


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Originally Posted by mikeb380
My F1n doesn't have a button with an "R". Are you misreading the marking "A" on the deck next to the shutter release? this is a two position turn switch which unlocks the advance "A" or locks it by turning to the "L" position.
I am not misreading the A on the shutter speed dial. It is indeed a rewind button and it is on the first pic HERE.


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B&B Triskeles
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- Continental Breakfast
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To the beach
Wednesday, July 29, 2015
Today is beach day, but before going to the beach we would visit a small town (old fisherman village) called Marzememi. first of all the trip that looked easy on the map turned out to be a long trip through forgotten streets in the middle of nowhere. Anyway ultimately we got where we needed to be. As such a nice village, but of this 'old fisherman village' little was left. It looked very touristic (nothing wrong with that) plenty of ...
Discovering the area
... of the park and we had to walk to the complete other side. From there we explored the park: the teatro Greco and ancient greek theatre that is now used for re-enactments of the old plays, the area where the stones were excavated by the slaves, the ear of Dyonisis, and so on. A number of places that were brought together in the park some of which were very nice, others very cool given the shade in the area.
Further trips from Noto to baroque cities
... It would not finish, so we tried different other programs, to get to the end, but even when it reached an end point it wouldn't open. So we tried and tried and tried and finally around noon time we were successful. Cloths back !
So we left our home around 12.15 pm to drive to Modico, another baroque city here in the neighborhood. Arrived there around 1 pm –which is the lucky time as you don't have ...
Idyllic Ortygia: Of Legends and Nymphs
... it is still a working city and the delicatessens and small markets were full of local shoppers. I was trying hard not to buy too much as we had long road journeys ahead of us through Tunisia and Morocco but I could not resist buying a small packet of exquisite rainbow coloured pasta.
Just below our hotel was the pretty Fonte or Fountain of Arethusa, a sunken artesian pond which flows out to sea. The site has a rather watery mythical ...
Day Trip to Syracuse
... is that the temple has an enclosed structure surrounded by columns, whereas the cathedral is an enclosed structure with an inner division of columns. In the Syracuse Cathedral, it is clearly evident that the temple's outer colonnade (peristasis) was enclosed to form the building's exterior walls. The originally, solid walls of the temple within were then carved out to create columns for the Cathedral's arcade. 2500 years of Syracuse's history ...


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All I Got Left is My THREAD BOMBS!
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January 10 2013, 12:04 AM
Zulu Romeo
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Re: All I Got Left is My THREAD BOMBS!
Brian wrote:
One of those "I have nothing to say to that, so here's a..." kind of threadbombs.
I could just watch that all day.
"In Germany, fear comes before sex... and if you're lucky, then a little bit later, an elf."
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8440 Woodfield Crossing Blvd.
Suite 460
Indianapolis, IN 46240
Phone: 317.471.0000
Fax: 317.735.0019
Corporate Address:
850 N. Harrison Street
Warsaw, IN 46580-3163
Paul Conrad
8440 Woodfield Crossing Blvd.
Suite 460
Indianapolis, IN 46240
Phone: 317.471.0000
Fax: 317.735.0019
Corporate Address:
850 N. Harrison Street
Warsaw, IN 46580-3163
Paul Conrad
Affiliated Service Providers of Indiana, Inc.
d/b/a ASPIN is a 501 (c) 3, non-profit behavioral health provider and education network.
Incorporated in November of 1995 ASPIN offers access to clinical providers in over 50 locations throughout the state of Indiana.
The ASPIN Behavioral Health Clinical Network maintains CARF accreditation under the Business and Services Management Network accreditation standards. The Behavioral Health Clinical Network is also a certified Managed Care Provider (MCP) for the State of Indiana Division of Mental Health and Addiction.
The ASPIN Education Network is certified to provide continuing education credits for several clinical disciplines.
Our Mission:
"The mission of ASPIN is to provide innovative educational programs, resource management, program development, and network management in collaboration with all healthcare entities to address health disparities and whole health management."
Who is ASPIN?
Milestones of Affiliated Service Providers of Indiana:
Join our team! ASPIN has two job openings in Indianapolis.
To View the Job Descriptions Click Here
Session One
Supervisory Basics 101
Define the basic concepts of Supervision.
Discuss the difference between Supervisor and employee.
Define the basic terms every Supervisor must know.
Fall 2015 - 8/12/15
Winter- 2016 1/13/16
Session Two
Dealing with the Generations: A Guide for the New Supervisor
Discuss communications in today's digital workplace
Explore how the generations interact and how to avoid conflicts
Learn strategies for dealing with an age diverse workplace
Fall 2015 - 9/9/15
Winter 2016 - 2/10/16
Session Three
Legal Issues and Your Workforce
Sexual and other harassment—why you are held to a higher standard
ADA—do you know what a request for accommodation sounds like?
Common wage and hour violations made by Supervisors
Fall 2015 - 10/14/15
Winter - 20163/9/16
To Register for ASPIN Training Click Here
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Cancellations for any fee-based ASPIN event must be made five (5) business days prior to the event, in order for fees to be refundable- NO EXCEPTIONS.
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Alright music collectors. Similiar to Rae's "Purple Tape", Boston's Get On Down
Tag: ghostface killah
This was supposed to be released last Fall. Fast forward three months later, we have the project's first single. The album is now due out April 16th and from the sound of Ghost's verse, he's back on his bullshit. Allow him to reintroduce himself.
Ghostface and Sheek both dodge Winter Storm Nemo and invaded The Shrine in Chicago last night. Here is DerickNtheCity's recap of the Wu-Block duo performing their classics. Wild out!
Tony Starks and Shallah's
High Times' annual Cannabis Cup went down in Amsterdam last November and Styles P, N.O.R.E., Ghostface Killah, and Scram Jones all made the trek. If you couldn't get pass customs, here's film from their adventure. We're getting high just watching this.
Often times, artists recycle beats. 10 years ago, Cam'ron reused Ghostface Killah's "Ice (Interlude)" for the title track of Come Home With Me. Producer Rsonist of the Heatmakerz sat with TheFactRemain to discuss the dual album placements.
Donnie G. and Pretty Toney were the latest guests on Cipha Sounds and Rosenberg's podcast. They spoke on the Wu-Block LP, reflected on their previous projects, past beefs and everything else in between.


text: DSpace Collection: http://hdl.handle.net/2440/5875 2015-10-04T17:00:29Z 2015-10-04T17:00:29Z Transcriptome profiling of the theca interna in transition from small to large antral ovarian follicles Hatzirodos, N. Hummitzsch, K. Irving-Rodgers, H.F. Rodgers, R.J. http://hdl.handle.net/2440/94822 2015-09-30T00:49:27Z 2013-12-31T13:30:00Z Title: Transcriptome profiling of the theca interna in transition from small to large antral ovarian follicles Author: Hatzirodos, N.; Hummitzsch, K.; Irving-Rodgers, H.F.; Rodgers, R.J. Abstract: The theca interna layer of the ovarian follicle forms during the antral stage of follicle development and lies adjacent to and directly outside the follicular basal lamina. It supplies androgens and communicates with the granulosa cells and the oocyte by extracellular signaling. To better understand developmental changes in the theca interna, we undertook transcriptome profiling of the theca interna from small (3-5 mm, n = 10) and large (9-12 mm, n = 5) healthy antral bovine follicles, representing a calculated >7-fold increase in the amount of thecal tissue. Principal Component Analysis and hierarchical classification of the signal intensity plots for the arrays showed no clustering of the theca interna samples into groups depending on follicle size or subcategories of small follicles. From the over 23,000 probe sets analysed, only 76 were differentially expressed between large and small healthy follicles. Some of the differentially expressed genes were associated with processes such as myoblast differentiation, protein ubiquitination, nitric oxide and transforming growth factor β signaling. The most significant pathway affected from our analyses was found to be Wnt signaling, which was suppressed in large follicles via down-regulation of WNT2B and up-regulation of the inhibitor FRZB. These changes in the transcriptional profile could have been due to changes in cellular function or alternatively since the theca interna is composed of a number of different cell types it could have been due to any systematic change in the volume density of any particular cell type. However, our study suggests that the transcriptional profile of the theca interna is relatively stable during antral follicle development unlike that of granulosa cells observed previously. Thus both the cellular composition and cellular behavior of the theca interna and its contribution to follicular development appear to be relatively constant throughout the follicle growth phase examined. 2013-12-31T13:30:00Z Pharmacokinetics of nifedipine slow-release during sustained tocolysis ter Laak, M.A. Roos, C. Touw, D.J. van Hattum, P.R. Kwee, A. Lotgering, F.K. Mol, B.W. van Pampus, M.G. Porath, M.M. Spaanderman, M.E. van der Post, J.A. Papatsonis, D.N. van 't Veer, N.E. http://hdl.handle.net/2440/94674 2015-09-27T23:45:24Z 2014-12-31T13:30:00Z Title: Pharmacokinetics of nifedipine slow-release during sustained tocolysis Author: ter Laak, M.A.; Roos, C.; Touw, D.J.; van Hattum, P.R.; Kwee, A.; Lotgering, F.K.; Mol, B.W.; van Pampus, M.G.; Porath, M.M.; Spaanderman, M.E.; van der Post, J.A.; Papatsonis, D.N.; van 't Veer, N.E. Abstract: OBJECTIVE: The pharmacokinetics of nifedipine as a tocolytic agent has not been studied in great detail in pregnant women and has instead focused on immediate release tablets and gastrointestinal therapeutic system (GITS) tablets. The aim of this study was to determine nifedipine slow-release half-life and distribution volume in pregnant women and to compare these with pharmacokinetic parameters of nifedipine in non-pregnant subjects described in the literature. MATERIALS: This is a study parallel to a trial studying women with threatened preterm labor between 26 + 0 and 32 + 2 weeks after initial tocolysis and a completed course of corticosteroids, who were randomly allocated to maintenance nifedipine (slow-release tablets 20 mg 4 times daily) or placebo. Exclusion criteria for the pharmacokinetic study were contra-indications for nifedipine, impaired liver function, and concomitant intake of inhibitors or inducers of the cytochrome P450 3A4 isoenzyme. Blood samples for measuring nifedipine plasma concentrations were drawn at t = 0, t = 12 hours, t = 24 hours, t = 48 hours, t = 72 hours, t = 7 days, and t = 9 days. METHODS: Pharmacokinetic parameters were estimated using iterative two-stage Bayesian population pharmacokinetic analysis by MWPharm© software. The study was designed to establish a correlation between body weight and nifedipine plasma level. RESULTS: The pharmacokinetic parameters of nifedipine slow-release tablets were determined from the data of 8 pregnant women. Nifedipine slow-release had a half-life of 2 - 5 hours, a mean distribution volume of 6.2 ± 1.9 L/kg (calculated while using a fixed biological availability of 0.45 taken from the literature due to lack of intravenous data in this population) compared to a half-life of 6 - 11 hours, and a distribution volume of 1.2 - 1.3 L/kg described in non-pregnant subjects in the literature. None of the women delivered during study medication. Study medication was continued for the duration of the pharmacokinetic study (9 days) in all women. A correlation between nifedipine plasma levels and maternal body weight was not demonstrated. This may have been caused by lack of power. CONCLUSION: Pregnant subjects in this study, using nifedipine slow-release tablets, showed a larger volume of distribution and a shorter elimination half-life than for non-pregnant subjects as published in the literature. 2014-12-31T13:30:00Z Planned home compared with planned hospital births in the Netherlands: intrapartum and early neonatal death in low-risk pregnancies Mol, B.W.J. Ravelli, A.C. Van Der Goes, B.Y. http://hdl.handle.net/2440/94487 2015-09-20T23:12:15Z 2011-12-31T13:30:00Z Title: Planned home compared with planned hospital births in the Netherlands: intrapartum and early neonatal death in low-risk pregnancies Author: Mol, B.W.J.; Ravelli, A.C.; Van Der Goes, B.Y. Description: Letter to the Editor 2011-12-31T13:30:00Z Transcranial non-invasive brain stimulation in swallowing rehabilitation following stroke - a review of the literature Doeltgen, S.H. Bradnam, L.V. Young, J.A. Fong, E. http://hdl.handle.net/2440/94394 2015-09-15T23:32:22Z 2014-12-31T13:30:00Z Title: Transcranial non-invasive brain stimulation in swallowing rehabilitation following stroke - a review of the literature Author: Doeltgen, S.H.; Bradnam, L.V.; Young, J.A.; Fong, E. Abstract: Abstract not available 2014-12-31T13:30:00Z


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Jo if you really wanted Wild Cherry you could get a dwarfing rootstock and graft on a wild cherry. It sounds daunting but it really isn't so difficult with a bit of practice and you've got little to lose. However the wildlife benefit of a cultivated cherry is probably about the same as long as it's not a sterile double. Everyone who's had a cherry tree knows how much the birds love cherries. I've haven't tasted mine yet the birds don't give me a chance.
On the subject of flowering lawn, Emorsgate seeds has an very good list of native grasses. If you are wanting to tick boxes you can't go far wrong with native grasses, they add a lot of benefit. Many moths feed specific grasses. Helps if the grasses are left a bit longer though. It's taken 5 years but my lawn near the house which my partner insists should be kept as 'lawn' not a 'meadow' is full of wild grasses that came in from the meadow and other than the bit under the bird feeder it's all very short, well relatively, the seed heads are about eight inches high but I think it looks fantastic and it hasn't been cut in about 5 weeks. That's down to keeping nutrients low though by removing all the cuttings. As I say under the bird feeder it's a very different story, more like an abandoned school rugby field.
It is a very difficult one. A lot really depends from what angle you're coming at. Personally being focused on Botany my emphasis is on the plants, I want to conserve the British Wild flora and I think if you focus on that then you won't got far wrong. Its very easy for an expert who's spent years studying to give a tiny fraction of their balanced knowledge in a few sound bites for it to then goes on the misinterpreted and used in totally the wrong way. My local Wildlife HQ is Rainton Meadows, now you'd think they'd have acres of meadows by the name, but they don't. Most of the area they have seems to be dedicated to birds so of course being a wooded island most of the area is taken up by woodland and ponds for water birds with very little managed meadow. It's a very big subject and there's lots of new data that goes against the grain of what I studied. I really do think though that if you want a wildlife friendly garden you've got to include as many natives as you can. It doesn't have to be a case of ticking off names on a list because there's a lot of native plants that don't support much wildlife and a lot of non-natives that do. But that comes down to knowledge again and wheather you are conserving insects for the sake of the insects or the birds that live on the insects. You can't really give rounded sound bites. You can't sum up years of research in a few lines of text that will be taken and absorbed in the right contecxt by total novices. To quote Buddhism don't turn your teacher into a demon. Don't get the wrong end of the stick and do harm. It made me smile on a GW episode last year when they interviewed an entomologist who gave a really well balanced explanation of what was the current thinking. He said something like many species of insects are very specific on the native plants they need while others really don't mind where the plants come from, then Monty, summed it up saying 'It's interesting that until a few years ago it was generally thought that native plants were key to getting insects into your borders but research has shown recently that it doesn't make much difference…" I screamed. NOOOOOOOOOO!!!!! Years of work by wildlife experts undone by a one line. Cart blanche to do what you like in the garden then. Oh boy!
The pfaf site should reed not very scientific, sorry. you're welcome nut.
I should add, just scanning through the suggestions, so many aren't native. Only one crab is native. But again check with the council what they keen by native. I have another list of pages that gives the benefit of certain native and non-natives to wildlife. Some surprises there.
I've just finished updating and double checking my list of natives. Here's the link You can choose where the links go to. Google, the pfaf site which is interesting but to very scientific and check any information before using it, and the Online Atlas of the British and Irish Flora. My site makes it very easy to use since it's laid out in a list. The list came originally from the Natural History Museum site, hence the name NHM. It was supposed to be a list of only natives, however I noticed several anomalies, and probably others did too which is probably why they've taken it down. Well, if you look you'll see a couple of abbreviations a, and n. I toyed with the idea of removing these plants since this indicates that the species aren't strictly native, however I felt removing plants that have been here since the Bronze age a bit hard line so I marked them 'a' meaning here since before 1492 and 'n', meaning here since 1492. I suppose I should make it clear what native is, 'native' means anything that arrived to our shores naturally, by it's own steam. So the Collared Dove is native though it's only been here since the 50's and the poppy is not though it's been here for ±5000 years because it was brought by Bronze age farmers and the dove just flew here. Agg. means a species that is really a collection of species, the most notorious example of that been the Dandelion and Blackberry where there's hundreds of debated subspecies. Not all subspecies have been included and some not at all, but where I thought they were of interest or when one sbsp was native and another wasn't I've tried to include it. I have still to include other sbsp but may never get around to updating all. It's taken me weeks to do this update and months if not years to get the time to do it. I suppose you should ask the council what they mean by 'native'. Anyway as you'll see by the site there's hundreds of very garden worthy items to choose from. And you can get them from many sites which abide by Flora Locale's code of conduct including Emorsgate Seeds. But again check the entry since many offer invasive or none-natives such as Fox and Cubs, you wouldn't want to introduce that to your garden. By the way, you mentioned, Bluebells, sorry, didn't get time to read every post. If you live near other households that have Spanish Bluebells then I wouldn't get Bluebells since they hybridise so readily. The amount of times I shout and the telly when someone is encouraging us to get English Bluebells. It was the first and biggest mistake I made when I moved in here. A complete waste of time and effort, though you could argue I'm supporting the growers, better to just make a donation for them to grow them.
"I'm glad my daughter's not the only soft-hearted one "
I 'adopted' two feral pigeon brothers when I lived in london, they both had hooked beaks and looked more like raptors than pigeons, called them Kes and Perry. They did okay for a year then I had to go away one Christmas so wasn't around to feed them. I never saw them again. I hope it's because they were fed by someone else.
Yes, bumblebees like to nest in old mouse holes, they're attracted by the smell of the mouse and they like the nesting material. I've had several nest in mouse holes and one in a rat hole under my garage but they seemed to get confused when I opened the garage door. The point of the article is to warn buying bee boxes is a waste of money? I made a cavity in a dry stone wall I built and put in an old mouse nest but they bees weren't interested. I thought it would be ideal but they didn't.
Yes, I'm sure it's a genetic mutation. Mustn't' be doing him any harm otherwise he wouldn't be around to take a photo of. Time will tell if the females are put off but the mutation is likely to be recessive so the chicks would look 'normal'.


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Doing business as usual will be a recipe for failure at the decisive climate meeting in Paris next December. 20 previous world climate conferences have shown this; and the two-week Bonn preparatory meeting of environment ministers in in May has offered very little hope for an outcome that will prevent an unsustainable temperature rise in the course of the century.
To avoid such a failure COP 21 has to adopt a radically new format.
Prime ministers will need to be present throughout the conference and take concrete energy policy commitments to be implemented within a given time frame. Halting a further increase of emissions after 2020 must be the top priority.
The "intended nationally determined contributions" (INDCs) are a first step in that direction. They create new transparency and – differentiated – commitments for individual countries. But those presented so far to the UN fall far short from containing global temperature within the two-centigrade increase considered as sustainable by Humanity.
The International Energy Agency, that groups the biggest per capita green house gas emitters, has presented a succinct road map for what governments should do concretely in order to tackle their emissions. This is the first time ever this happens before a COP meeting; the COP 21 should agree on this road-map before getting lost in its usual agenda points:
Presently 13 per cent of global energy-related emissions benefit from such subsidies at a level of $ 113/ton of C02. Several countries in the Middle East, South-East Asia and Latin America will have to correct their policies.
This is above all an issue for USA, India and some South-East Asian countries.
Raising energy efficiency must be the top priority for all countries. This is done most easily by the introduction of technical standards for fuel consumption of cars and trucks, insulation of buildings, etc. USA and EU have best demonstrated the effectiveness of this approach. All other major emitter countries should therefore follow their example.
If all major energy consumer countries followed these basic recommendations, energy-related emissions would start declining by 2030. The use of coal, the most polluting fossil fuel, would accelerate its phasing out; and China would see its emission growth decouple from its economic development by 2020.
The Paris conference will only be successful in substance if the main parties agree to improve their INDCs and the underlying energy policies to keep the world on a "two centigrade track". This should therefore be the overriding priority for the French host and the Conference Chair.
Brussels 20.06. 2015 Eberhard Rhein
In the last eight years US energy and climate policy has made impressive strides towards sustainability. This is due essentially to President Obama who has invested more in climate policy than any other US President, overcoming the ideological opposition from public opinion and Congress through recourse to executive orders.
Over decades US fossil energy consumption and green house emissions have kept soaring. With some 17 tons per capita emissions they were among the highest on earth, comparable to those of Gulf countries, Canada and Australia.
In 2014 US emissions have, for the first time ever, registered a decline. The government projects a decline of at least 27 per cent until 2030 compared to 2005. This would still leave per capita emissions at unacceptably high levels, about 50 per cent higher than those of the EU (seven tons).
The US policy is essentially based on raising energy efficiency. The Environmental Protection Agency plays a crucial role, usually in conjunction with Transport and Energy Departments.
"Technical standards" are the name of their magical formula. For their definitionthey explore the optimum of energy and minimum of emissions (e.g. CO2 ) that can be "squeezed" out of a ton of coal, oil or gas, first with available and then with innovative technologies. On that basis they elaborate standards for cars, high duty vehicles, power plants and air planes, in close collaboration with the stakeholders from industry and trade unions. To facilitate their acceptance, the introduction takes place in phases stretching over several years.
This technique is similar to what the EU is also doing, in particular for cars. But while the EU operate in abstract terms of CO2 emissions (e.g. fleet average of 125 g per km)the US establishes consumption levels (gallons per 100 miles).
The US approach directly shows consumers the economic advantages stemming from the policy measures. The EPA keeps "selling" them.
An example are the latest efficiency and emission standards for medium and high duty vehicles,for which will be introduced progressively from 2016 to the mid-twenties. The extra costs of the vehicles will be recouped within only two years and yield an high profitability for vehicle owners.
The US has put priority on sectors consuming most fossil energy.
Road transport has been the first target, first cars and light weight vehicles, followed by that medium and heavy duty vehicles account for almost 23 per cent of US domestic green house gases.
Fossil-fuel power generation, in particular coal power plants, have been tackled in parallel. Fossil-fuel power plants account for almost one third of domestic green house gas emissions, the single most important consumer of fossil fuels.
Air transport, which accounts for 3 per cent of total US green house power emissions, will be the next target to be addressed domestically and internationally, in the context of the International Civil Aviation Organisation, with the hope of establishing standards before 2020. That would be a great performance considering the continuous increase of global air traffic.
The US approach is at least as pragmatic and cost-effective as the EU method of progressively reducing emissions from power plants, steel, glass, pulp/paper, copper, aluminium and other energy-intensive industries.
In addition, the US promotes biofuels, solar and wind, through a combination of tax credits, subsidies and feed-in tariffs. Though it has not not established mandatory federal targets, 11 per cent of national energy have been generated in 2013 by renewable sources, essentially hydro, wind and solar.
In conclusion, since 2008 the US has become one of the vanguards of global energy and climate policy. But it has a very long way to go bring US emissions down to acceptable level. It considers innovation and technology as the key to phasing out green house gas emissions by the end of the century and has properly adopted a strategic long-term approach.
Brussels 22.06 2015 Eberhard Rhein
Boeing outlined at Le Bourget in France a variety of leading-edge technologies with the potential to make the flying experience more comfortable and exciting, as well as making airplanes more economical and efficient. Boeing presented an overview of its research and development efforts at the Paris Air Show.
"We really feel that we've taken our airplane designs to the next level," said Mike Sinnett, vice president of Product Development, Boeing Commercial Airplanes. "For nearly 100 years, Boeing has delivered market-leading innovations to airlines around the world. Our latest technological advancements reinforce our commitment to innovation leadership."
Sinnett described innovations in operational efficiency, connectivity, advanced materials, cabin experience and advanced technologies that demonstrate Boeing's market-leading focus on future technology. Boeing's focus on innovation also extends to its production systems and the services it provides to airline customers.Some of the advances being developed include:


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Community Events
Carlos Boozer of the Chicago Bulls takes a break from baking cookies... News PhotoBaking,Basketball - Sport,Carlos Boozer,Chicago Bulls,Cookie,Deerfield - Illinois,Horizontal,Illinois,NBA Pro Basketball,Portrait,Sheri L. Berto Center,Sport,Sports Team,USA,USOPhotographer Randy BeliceCollection: National Basketball Association 2012 NBAEDEERFIELD, IL - DECEMBER 09: Carlos Boozer of the Chicago Bulls takes a break from baking cookies to pose for a picture during the team's USO / Chicago Housing Authority Holiday Party on December 9, 2012 at the Sheri L. Berto Center in Deerfield, Illinois. NOTE TO USER: User expressly acknowledges and agrees that, by downloading and/or using this photograph, user is consenting to the terms and conditions of the Getty Images License Agreement. Mandatory Copyright Notice: Copyright 2012 NBAE (Photo by Randy Belice/NBAE via Getty Images)


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Primary 4 Visit the MC Escher Exhibition
01 Oct 2015
The Primary 4s visited the wonderful MC Escher exhibition at the Gallery of Modern Art II on Thursday. Miss Knox had arranged for P4X and P4Y to be hosted by Emily and Duncan, from the Gallery, who took the girls on a tour of Escher's most famous works and described the history of Escher's work and the efforts he went through to produce his final prints. The girls particularly loved "Metamorphosis" and the Escher Maze in front of the gallery!
Choosing a School – Some Frequently Asked Questions
24 Sep 2015
See our new short video clips to hear Anne Everest talk about some of the questions she is regularly asked by parents when they are choosing a school. Click here to view the other 2 videos in this series.
St George's University Destinations and Bespoke Career Guidance
17 Sep 2015
St George's Sixth Form students are highly successful in securing competitive places on an impressive variety of courses at a wide range of leading universities, including the Russell Group and Oxbridge. Many of this year's leavers have gained their places to study a range of subjects including Business, Chemistry, English, History, Law, and Medicine. The vast majority of the girls secured their places to their first-choice of university, which includes Russell Group Universities such as Bristol, Cambridge, Durham, Edinburgh, Exeter, Glasgow, Newcastle, Oxford, St Andrews and UCL. Over 32% of the girls are going on to study STEM (Science, Technology, Engineering, Mathematics) subjects such as mathematics or sciences; no ...