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services, as well as education and wellness programs, to residents of its communities. These programs are focused on wellness and physical fitness to allow residents to maintain maximum independence. These services provide continuing education opportunities for residents and their families through health fairs, seminars, and other consultative interactions. The therapy services the company provides include physical, occupational, speech and other specialized therapy and home health services. The home health services the company provides include skilled nursing, physical therapy, occupational therapy, speech language pathology, home health aide services, and social services as needed. In addition to providing these in-house therapy and wellness services at its communities, the company also provides these services to other senior living communities that the company does not own or operate and to seniors living outside of its communities. The company also has begun offering hospice services in certain locations. The Brookdale Ancillary Services segment includes the outpatient therapy, home health and hospice services provided to residents of its communities, to other senior living communities that the company does not own or operate and to seniors living outside of its communities. Management Services The company operates certain of its communities pursuant to management agreements. In some of these cases, the community is owned by third parties and, in other cases, the community is owned in an unconsolidated venture in which the company has an ownership interest. As of December 31, 2014, the company operated 61 communities, representing 8,396 units, for third parties and 100 communities, representing 19,287 units, for unconsolidated ventures in which the company has an ownership interest. As of December 31, 2014, these communities consisted of 49 retirement center communities, 77 assisted living communities and 35 CCRCs. Strategy The company's strategy is to be the leading provider of senior living solutions, built on a large and growing senior housing platform. Main Elements of its strategy includes the following: organic growth in core business, including expense control and the realization of economies of scale; growth through strategic capital allocation; growth through development of a market leading Brookdale brand; and growth through innovation of product offerings, including Brookdale Ancillary Services programs. Customers The company's target retirement center residents are senior citizens age 75 and older who desire or need a supportive living environment. Its target assisted living residents are primarily senior citizens age 80 and older who require daily assistance with 2 or 3 ADLs. The company's target CCRC residents are senior citizens who are seeking a community that offers various services and a continuum of care so that they could 'age in place'. Government Regulation Some of the laws and regulations that impact the company's industry include state and local laws impacting licensure, protecting consumers against deceptive practices, and affecting the communities' management of property and equipment and how the company otherwise conducts its operations, such as fire, health and safety laws and regulations and privacy laws; federal and state laws designed to protect Medicare and Medicaid, which mandate what are allowable costs, pricing, quality of services, quality of care, food service, resident rights (including abuse and neglect) and fraud; federal and state residents' rights statutes and regulations; Anti-Kickback and physicians referral (Stark) laws; and safety and health standards set by the Occupational Safety and Health Administration. The company is also subject to certain federal and state laws that regulate financial arrangements by health care providers, such as the Federal Anti-Kickback Law, the Stark laws, and certain state referral laws. Competition The company's competitors include Capital Senior Living Corporation; Sunrise Senior Living, LLC; Life Care Services, LLC; Atria Senior Living Group; HCP, Inc.; Ventas, Inc.; and Health Care REIT, Inc.
brookdale senior living inc
(BKD:New York)
Contact Info
111 Westwood Place
Suite 400
Brentwood, TN 37027
United States
Phone: 615-221-2250
Fax: 615-221-2289www.brookdaleliving.com
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- Re-bush all major suspensions: ie: Hutch, Reyco, Freuhauf, Trans Pro, Air Ride, Neway, etc.
- Replace Bad Leaf Springs
- Replace Bad Air bags
- Install new Axles
- Install Hutch Suspension Kits
- Inspect/repair air brakes
- Install New Kingpins
- Replace Damaged Spindle Ends
- Replace hangers, Equalizers, & Other Parts
Trailor ServicesJanuary 21st, 2009
Tractor ServicesJanuary 21st, 2009
- Rebush all major suspensions,ie: Hedrickson, Mack, Neway, Chalmers, K-W, Peterbuilt, Freightliner, etc.
- Repair / Replace damaged Leaf Springs
- Replace bad air bags
- Install new lift axle kits
- Re-bush Lift Axles
- Air Brake Jobs and Inspection
- Press New Mack Trunnion Shaft
- Repair / Replace Damaged Frame Rails
- Change Wheelbase & Roll Axle
- Air Suspension Conversions
- Replace or re-bush bad Hangers & Equalizers
- Re-bush or make new T/Q Arms
- Make U-bolts as needed
- Install new Shock Absorbers
- Replace damaged Drive Axle Spindles
Light Duty ServicesJanuary 21st, 2009
- Remove & Replace Damaged leaf Springs
- Install Helper Kits both Spring & Air Ride
- Level Service trucks
- Build-up Leaf Springs for H-D Service
- Install Hangers, Shackles, Shocks, etc.
Light Duty Trailer ServicesJanuary 21st, 2009
- Repair or Replace Damaged leaf springs
- Install New Axle Kits
- Replace Bad Hangers, U-Bolts, Equalizers etc.
Bee-Line AlignmentJanuary 21st, 2009
- Complete vehicle, frame & axle Alignment Services
Homepage TextJanuary 20th, 2009
Front End ServicesJanuary 15th, 2009
- Bee-Line Laser Alignments-cars, pickups, tractors, trailers
- Truck Tire Spin Balancing
- Rebush Kingpins
- Bore & Sleeve Steering Axles
- Rebush bad front spring hangers
- Replace Coil Springs
- Replace Leaf Springs
- Re-bush A-Arms & Other front end parts
- Align Lift Axles
- Inspect Steering Box
- Align Steering Wheel
Hello world!December 10th, 2008
Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

subset: commoncrawl


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- 41Promote
Tote Bag
Meanwhile.. Landscape IVby Stroke A Bird
Our quality crafted Tote Bags are hand sewn in America using durable, yet lightweight, poly poplin fabric. All seams and stress points are double stitched for durability. Available in 13" x 13", 16" x 16" and 18" x 18" variations, the tote bags are washable, feature original artwork on both sides and a sturdy 1" wide cotton webbing strap for comfortably carrying over your shoulder.
This is really wonderful. Thank you for sharing.
Thanks Zach!
I like You work..................................................>
Thank you
Thanks Aimee
Great work! Nice portfolio you have here!
Thank you Jacqueline!
This is quite beautiful!
Thanks Nikola!
Wow this is like sooo Rotterdam
cool! :)
@Zebedeus: Noway! It's Berlin..
See More Comments


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Trustworthy reviews are our priority. Businesses can't pay to change or remove reviews.
The Hyatt Regency was an amazing venue my Husband and I could not have asked for a better time! We had the pleasure of working and planning our wedding with Jennifer Payne, Hyatt's event coordinator. Jennifer was truly a godsend seeing as how I had no help in planning my wedding because my husband was away with the military. The staff at the Hyatt was an absolute pleasure to work with and I would love to work with them again in the future! During our planning process the Hyatt employees especially Jennifer became more than just employees planning our event they became family and I will be sure to stay in touch with them in the future. Our experience with the Hyatt of Clearwater was truly amazing and they made our event even more amazing than we had imagined! My advice to anyone looking for a wedding or event space on the west coast of Florida is to book with the Hyatt of Clearwater and to plan your event with Jennifer Payne!
Capri was not only professional but very friendly. She made everything run smoothly. Every request we had was addressed promptly and there was never a moment of stress because she took care of every detail so well. I strongly recommend her and all the services she provides!! Our wedding was perfect because of her enthusiasm and willingness to make our day just perfect!
Great Venue! awesome staff! Can't wait to go back! You can't go wrong with Hyatt in Clearwater. We had a beautiful ceremony right on the beach followed by a fantastic reception. The food was excellent, but probablyt he best part of the week was just how well everyone in the building treated us.
From the moment I stepped foot on top the sky terrace at the Hyatt I knew that was where I wanted to get married. The view is spectacular. The event coordinators at the Hyatt Regency on Clearwater Beach were awesome. Lindsey Sikes really knows what she's doing and makes sure that no detail gets missed. She was easy to communicate with and always responsed in a timely manner. Her assistant Megan was a pleasure to work with as well. They really put my worries at ease and my wedding day went off without a hitch. I couldn't be any happier. I'm so glad I chose to get married at the Hyatt, and I know my family and friends will be talking about it for a very long time.
I cannot thank begin to thank the Hyatt staff for their amazing venue, services and talent in helping plan my wedding from out of starte. Capri and Megan were amazing. I was very nervous planning a wedding from Minnesota; however everything was easy and perfect.
The vendor recommendations get an A+ in my book. Weddings on a whim made finding and trusting someone to marry is easy. They were kind and very organized. Heather from Rose Gardens made picking out flowers easy. She helped me visualize what the terrace would look like for my wedding without ever seeing it. The Hyatt was a great place to have a destination wedding. The terrace location was beautiful and felt like a dream. The day of the wedding was relaxing and fun! The Hyatt had a great spa to relax at. Capri and Megan did everything while I got to relax. The ceramony and dinner were perfect. I cannot thank them enough.
We had the most amazing and perfect wedding at the Hyatt. Everything was so simple to plan, even though we live in Pennsylvania. We planned our wedding in just under 3 months and still there was no stress. I would never hesitate to recommend this venue to anyone. Our coordinator was Capri who walked us through it all. She is a wonderful person who did not miss a single beat. There were no flaws on our special day, everything went as planned. The food was superb, sky terrace ceremony unforgettable, caladesi room perfect for our 20+ guests. I had the most beautiful day to marry the man of my dreams. Thank you Hyatt for all the wonderful memories!!
Congratulations Mari! We're so happy for you and your new Husband and are thrilled that we were able to help make your day so special!!
I HIGHLY recommend celebrating your special wedding weekend at this wonderful hotel. Already married? This is a GREAT place with wonderful service, amenities, HUGE rooms to take your friends or family for an amazing weekend at the beach!
Words can't describe the amazing hospitality, service, and quality provided by the staff at the Hyatt Regency Clearwater Beach. I could not have asked for a better wedding coordinator, Lindsey Sikes! She makes happen whatever idea you have in your head. She is a great stress reliever, taking care of a lot of behind the scenes things without stressing the bride out further. Her attitude, spirit, and great personality make her an essential piece of the special day! Also, the banquet/dinner could not have flowed more perfectly, thanks to Nikolay and staff.
Overall, from the moment I walked into the hotel to check into my room, being greeted with champagne and warm hugs, could not have set the stage even better.
This hotel truly provides high class service, with personal touches, and a lot of thought and dedication put into details that made our wedding day absolutely perfect.
My highest recommendations to this great place!
Thank you so much for the amazing review Nicole! We are so thrilled that we were able to be a part of your day and help to make it everything you dreamed of. We wish you and Travis all the best in your future together!
My husband and I cannot compliment the Hyatt enough! Our wedding was absolutely PERFECT, can't thank all the staff enough that were involved in making our day so special! Our wedding was in February - ceremony on the Sky Terrace, cocktail hour on the 8th Floor Caladesi and our reception in the Aqualea ballroom. Everything was SO beautiful! We originally had a different coordinator but about 5ish months before she left and we got re-assigned and Lindsey was our new coordinator. She was awesome! She handled everything with such professionalism, always responded to my million emails right away, never had to worry about a single thing! I do have to compliment the entire staff at the Hyatt though, every time we went there during the planning process we always felt so welcomed and felt like we were right at home and knew everyone! We would always start off any visit at the bar to celebrate with a cocktail from our favorite bartender, Rob! We actually ended up requesting him to be a bartender on our wedding day and they made it happen! The head of the catering department was such a sweetheart, we loved her at our food tasting and even more at our wedding! She kept coming up to us and made sure my husband and I were eating and that we had whatever drink we wanted. Our wedding day went so smoothly, and everyone that came couldn't stop complimenting us! We had quite a few guests tell us it was one of the best weddings they've been to, and although I'm sure that is what you're suppose to say to any bride and groom, I truly felt like our wedding was one of a kind and all of our guests has an amazing time! Food was amazing too! My husband and I grew up in Clearwater so Clw beach was always special to us, but choosing the Hyatt was definitely one of the best decisions we made - we would HIGHLY recommend you having your wedding here if you want to have the perfect wedding day! To the entire staff at the Hyatt, THANK YOU! Book now and go have a drink from Rob -Mr. & Mrs. Ristoff
Planning a wedding where your venue is 4 hours away proved challenging at times. But with the help of Lindsey at the Hyatt my big day went smoothly. Lindsey was always reachable, either by phone or email, and would answer all of my millions of questions regarding details and times. She provided helpful insight on what vendors they have worked with and recommended local places when I didn't know where to look. All of our special requests with the food for the reception and the rehearsal dinner she helped us get and set up. Thank you for making our wedding such an amazing day!
Thank you for your comments Lourdes! We are thrilled that you had such an amazing experience at our Resort and that Lindsey took such exceptional care of you!
I live nearby, so I was familiar with the resort. I take out of town guests here for lunch/dinner because the views are so great. After speaking with the event coordinator, Capri, I choose the Hyatt for our wedding venue. Her personal touch made the difference with the superb outcome of our day. The accommodations are outstanding: comfy beds, patios with the views, full kitchen, and living areas in each room, and again, the views! We had 30 some guests, and used a smaller space, the Caladesi Room. I absolutely loved it. The sun setting behind us trumped any decoration. The food was perfectly executed, plated, and served over four courses. Each staff member made certain things went off without a flaw. The room was the perfect size, and the patio area overlooking the gulf with cocktail tables were such a hit. All details were addressed, and they didn't let me miss a thing. Such a fantastic day!
Everybody was awesome the staff made our special night a night to remember so much fun and a fairytale wedding thank you
My wedding at the hyatt in clearwater beach was a dream come true. Lindsey and Meghan were absolutely amazing. Extremely helpful with all the small and large details of the wedding. The day of the wedding everything went extremely smoothly and seamless. The wait staff was incredible. Nicholai, staff captain, was the true definition of excellence. Erin was great. Honestly I cannot express in words how happy and thankful I am to everyone at the hyatt for making my wedding perfect.
The absolute best day of our life. Thai was amazing, she took great care of us and our guests. The staff was accommodating and went above and beyond. My husband and I had a beautiful beach wedding in front of the Hyatt on the beach and then our very intimate reception on the beautiful 8th floor caladesi room. I could not have been more happy. The Hyatt Clearwater will be our anniversary vacation every summer so we can forever remember the perfect and most special day of our life. Thank you to my wedding coordinator and now friend, Thai, thank you to the entire staff, and all that made both is and our guests feel so special.
They Hyatt catered to our every need and desire while planning the wedding as well as on the big day! Despite the rain on our wedding day the staff was able to re-group and set up our back up location quickly and made our guests feel comfortable. It was my dream venue and they made my dream wedding a reality. Worth every penny.
Our experience with Thai was great. She helped us with every step & detail of our Weddding.
I am 9 months late writing this review but I can't say enough wonderful things about our May wedding at the Hyatt! my husband and I were originally getting married in Jamaica, and had to cancel 5 months prior and change our entire wedding. Luckily, I called Thai and she was amazing!!!! She recomended all of my vendors and planned everything on such short notice! She was so helpful on the day of, making sure the guys and girls were all taken care of and fixing whatever needed to be fixed right away! My husband and I talk about how amazing our wedding was ALL the time and we owe it all to Thai and the wonderful staff at the Hyatt Regency! We stayed in a beautiful suite, and literally everyone that works for the hotel brought us a bottle of champagne when they found out we had just gotten married! Let me tell you, coming from NY and never having stayed at the hotel or eaten the food and just going there blind was a little nerve wrecking....but we had our tasting 3 days before the wedding and the food was INCREDIBLE! Everything we tasted was better than the last....our guests loved the food and the atmosphere! We want to tell you that if you are looking to have your wedding in Clearwater, look no further...this is the perfect venue and Thai and her staff are unbelievable! You will not be disappointed. Thank you Thai!!! :) :)


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This is a very nice Residence Inn. We picked this property for a sightseeing trip to Colorado because is was close to most everything in Northern Colorado, had a great price (which may have been attributable to nearby highway construction which, other than the first night in the dark, wasn't that bad and should not last too much longer).
The rooms are the largest I have seen in any Residence Inn .. our 1-bedroom suite was over 500 sq. ft. The things that count at a Residence Inn were all present - good breakfast, clean rooms, quality mattress, full kitchen, free weeknight dinners incl. beer and wine, etc. Plus, Ryan the manager runs an excellent ship. As an example, on one very windy day (45 to 65 mph winds) something was banging somewhere. Not wanting it to continue into the night I called the front desk. A few minutes later I looked out the window from our 4-th floor suite and saw a fellow walking around and looking up. I pointed where I thought the sound was coming from and invited him into the room to hear for himself. Turns out he was the manager and began to open HVAC panels to check for anything loose. He fixed it himself because the maintenance staff had left for the day .. I thought that was above and beyond the call of duty.
There are lots of stores and malls close-by and the #1 rated Denver restaurant (on Tripadvisor in May) was just on the other side of the hotel next door and had good take-out.
All-in-all, a very nice stay and will return to this Residence Inn the next time we are in Denver.


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Asuncion Ridge Vineyards » Winery Events
Friday, October, 9 2015
Billy Foppiano in Concert
Asuncion Ridge 725 12th Street Paso Robles
Billy Foppiano is one of the Central Coast's most talented & versatile guitarists. Dubbed "the Guitar Wizard" by music reviewers, Billy plays & sings a warm mix of popular rock, blues, jazz, country & more. Enjoy your favorite Asuncion Ridge libation and listen to this pro!
Saturday, October, 10 2015
Eric Brittain in Concert
Asuncion Ridge Vineyards
Eric Brittain is a talented multi-instrumentalist who plays guitar, mandolin, fiddle & more! He performs Americana, Jazz, Folk, Blues as a solo act & with others all over the Central Coast. Enjoy his music with a glass or bottle of our wine in our cozy Downtown Paso lounge.
Saturday, October, 24 2015
Noach Tangeras in Concert
Asuncion Ridge 725 12th Street Paso Robles
Singer/Songwriter Noach Tangeras gets her inspiration from folk, country, blues & rock. Her sound is reminiscent of Patsy Cline, Janis Joplin, Alison Krauss & Joss Stone. Heard around the Central Coast in the Noach Tangeras Band, she'll be playing solo at Asuncion Ridge.
Friday, October, 30 2015
Steve Tracy in Concert
Asuncion Ridge Vineyards
Steve Tracy is a world renowned guitar player who sings, plays guitar, slide & harmonica. He has been performing for 50 years & has played with Denny Carmassi, Norman "Spirit in the Sky" Greenbaum, Sammy Hagar, Bobby Blue Bland, & Sly & the Family Stone. Wine BTG or bottle.
Learn more about our vineyards
725 12th Street
Downtown Paso Robles, 93446
Sun-Th 12 - 6 p.m.; Fri & Sat 12 - 8 p.m.
Tasting Fee
$10/One fee waived per bottle purchased
Wines Produced
Cabernet Sauvignon
Pinot Noir
Red Blend
Red Rhône-Style Blend
Bordeaux-Style Blend
Red Meritage Blend
Late Harvest Sauvignon Blanc
Sauvignon Blanc
Late Harvest
Dessert Wine
Bed & Breakfast
Gift Shop
Pet Friendly
Special Event Facilities
Tasting Room
Vineyard Tours
Winery Tours


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"Simply put, Congress may tax and spend." With those historic words, the Supreme Court forced upon the United States a bleak dawn of a brave new world in which the federal government cannot be checked in its march toward totalitarianism. In a 5-4 decision the Supreme Court upheld the joint venture of the President and Congress to force every American, regardless of ability or desire, to purchase a qualifying health care insurance plan by 2014 or face a tax penalty for failure to comply.
On Monday the Supreme Court issued its ruling on the constitutional challenge filed against the Arizona immigration statute. In the decision, one of the four provisions at issue was upheld, while the remaining three were struck down.
Today's Supreme Court decision upholding ObamaCare means November's elections will be a national referendum on repealing ObamaCare.
Republican voters in Utah Tuesday handed six-term Senator Orrin Hatch another victory that will more likely than not put him pack in Washington until 2018 when the self-described "tough old bird" will be 84 years old. His primary opponent Dan Liljenquist, a former state senator and Bain Capital manager, didn't even manage to capture his home county's vote in Tuesday's GOP primary.
Watching the television pundits fret over campaign finance is amusing, because the solution to their problem is right under their noses. They just don't want to see it. As long as government has the power to sell privileges, people will spend big bucks to influence elections. The wealthy and well connected will always have better access to government than regular people.
Politicians seem to have a special fondness for words that have two very different meanings, so we are likely to hear a lot of these kinds of words this election year. "Access" is one of those words. Politicians seem to be forever coming to the rescue of people who have been denied "access" to credit, college or whatever.
Obama's activities at this past weekend's "Gay Pride" parades in cities such as New York, Chicago, and San Francisco, prove again that the Democrats are no longer the party of the common man. They are now the party of the uncommon man.
As the sprawling surveillance site being constructed by the National Security Agency (NSA) in Utah grows larger and nearer completion every day, the domestic spy service remains tightlipped about just how much and what kind of personal electronic data they have already collected and collated. Not only does the NSA refuse to provide such information, it insists that it cannot be forced to.
In July of 2011 and again in May 2012, Senators Mark Udall (D-Colo.) and Ron Wyden (D-Ore.) wrote a letter to James R. Clapper, Jr., the Director of National Intelligence, asking him a series of four questions regarding the activities of the NSA and other intelligence agencies regarding domestic surveillance.
"The United States is abandoning its role as the global champion of human rights," former President Jimmy Carter charged in a June 24 op-ed in the New York Times, charging the United States government with assassination attempts through the use of drones and massive domestic surveillance against the privacy rights of American citizens. But Carter cited the United Nations' Universal Declaration of Human Rights rather than the U.S. Bill of Rights as the inspiration to follow and restore a respect for the inalienable rights of others.
American taxpayers dole out $80 billion every year to subsidize food stamps for the poor, but are unsure of where and how their hard-earned dollars are being spent. Ranging from candy to potato chips to steak dinners, food stamps can be used to purchase a variety of foods, and are accepted at gas stations, fast-food restaurants, retail stores, and in some areas, even high-scale restaurants.


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For the past month or so, the bottle nipple become flat every time LO suck on it. We have 6 nipples and most of them are like that. We thought maybe nipples have been in use for too long (since LO is 6 mos old), so maybe the plastic become too soft so it's easily flatten when baby suck on it. We got 2 new nipples but are still getting the same result. We already have extremely hard time feeding this LO. Now because of that, LO only can drink very little from each sucking and the feeding is taking forever. Any mom has similar experience? What can I do to fix that? We are using dr brown nipple size 3 by the way. Will switching to size 4 helps?
Bottle nipple is flatten when LO suck on it. Help plz!
Posted 03/16/2013
Comments (6)
Posted 03/16/2013
You might need a whole new set of bottles? Each child is differnt the ones I would try 1st is the Walmart ones they are cheap and seem to work for a lot of different babies. Also you might want to start trying sippy cups instead.
Posted 03/16/2013
I found that happening too w my Medella bottles. I think it happens cause of the suction due to on air releasing, it doesn't happened w my playtex vent air flow bottles. What works for me is loosening the lid a bit, it helps excess air come out a bit. So twist it just enough for fluid not to come out but not super right. It works for us. Good luck!
Posted 03/16/2013
Loosen the ring first. Ive never had this happen with my dr browns bottles but ive never gone above size two.
pui106 · Original Poster
Posted 03/16/2013
I will try to loosen the lid a little bit. LO is fine drinking water from sippy cup. But if she finds out its milk, she spits it out right away and stop drinking from the sippy cup. It looks like she just hates milk.
pui106 · Original Poster
Posted 03/17/2013
Hi just want to say loosen the lid solved the problem. Thanks alot for the suggestion!
Your growing child
Your 3 1/4-year-old: Tracking growth
Time to get out some pictures or videos of your child at 1 or 2 and compare how much bigger and stronger she is now. Read More
Your 3 1/4-year-old: Storytelling
As language skills evolve at age 3, kids start to tell more elaborate stories. Listen and enjoy. Read More
Your 3 1/2-year-old: Facing fears
Bedtime fears are common for preschoolers, but children can be frightened of all sorts of things. Read More
Your 3 1/2-year-old: Magical thinking
Learning to distinguish between fantasy and reality is a gradual process for kids. Read More


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You are a fan of defence mick ? Come to discover the best forums defence mick on the internet and share your experience with a community fan of defence mick . You can also build a forum defence mick and create your online discussion.
Dennis Martins Combative Community. COMBATIVES. Combatives Dennis Martin CQB CQC self protection self defence self defense rbsd scenario training WWII Fairbairn Sykes Biddle Applegate Nelson S. O. E O. S
combatives, dennis, martin, self, protection, #defence, defense, rbsd, scenario, training, wwii, fairbairn, sykes, biddle, applegate, nelson, s.o.e, o.s.s, shanghai, gutterfighting
A message board dedicated to constructive discourse and the archiving of useful information in all aspects of practical self-defense with an emphasis on unarmed personal combat.
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Free forum : This website is for everyone who is interested in martial arts which can help you to save your or someone's life and its very good for your health so you are here and let's do it .
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Blogs from around Africa.
We just released a new version of the Guide to Greener Electronics. This time ranking 15 gadget and electronics companies on energy, greener products and sustainable operations. HP takes the lead at 5.9 out of a possible 10 points, followe... Read more >
This weekend, Greenpeace will be casting some bright, solar-powered light over all the ways we can use renewables now!
We're hosting a renewable energy-powered picnic at Soweto's Mofolo Park from 10am on Saturday 12 November.
We will be showcasing... Read more >
Logging truck on the Siforco road between Engengele and Kpenge in the confession K-8 near Bumba.
© Thomas Einberger / Greenpeace
In the Democratic Republic of the Congo (DRC) violence associated with logging companies is not uncommon, but evidence and testimonies collected by Greenpeace show that the Yalisika community of Bosanga was punished with exceptional violence... Read more >
Greenpeace activists chain themselves to the front gate of the construction site of Kusile coal plant in Mpumalanga, South Africa, in protest of South Africa's addiction to coal power.
© Greenpeace / Shayne Robinson
Today, Greenpeace Africa has brought something very far away from the minds of most South Africans to the top of talking trends. "Confronting Kusile" is the phrase making the rounds online this morning, and it's got many regular South Africa... Read more >
Greenpeace activists scaled a crane on the construction site of Kusile power plant in South Africa to protest their country's complete reliance on coal power.
© Greenpeace / Michael Baillie
This morning i'm writing from the top a 110m high crane inside the construction plant of Eskom's next collosal coal-fired power station, Kusile.
I'm here with five other climbers to highlight the true cost of coal power in South Africa. Our... Read more >
Greenpeace activists hang from a crane inside Eskom's Kusile power plant in the Delmas municipal area of the Mpumalanga province, with banners reading 'Kusile: Climate Killer'. Greenpeace is calling on the state owned utility ESKOM to abandon Kusile coal fired power plant, which is set to become world's fourth most polluting power plant in terms of greenhouse gas emissions and to instead invest in both green energy sources and jobs.
© Shayne Robinson / Greenpeace
South Africa has a fossil fuel addiction. Our drug of choice? Coal. And at a time when actions affecting the climate in any way should be taken with great care, our government continues blindly to cultivate its infatuation with this dirty, s... Read more >
Activists from Greenpeace Africa drive three dumper trucks filled with coal to the front of the Eskom Megawatt Park to unload five tonnes of the rock outside their offices. Effectively blocking one of the entrances to the building with the coal. The activists also hold banners calling on Eskom to 'clean up it's act', to "Stop Coal", to end their usage of the outdated fossil fuel; to publicly demand that Eskom stops the construction of the Kusile coal-fired power station and and shift investments to large-scale renewable energy projects.
© Shayne Robinson / Greenpeace
South Africa has a coal addiction. But just because something is a habit, doesn't mean you shouldn't quit.
It didn't take Eskom long to respond to the staggering results of our recent report "The True Cost of Coal in South Africa: paying th... Read more >
Last week, the tech and business media were all a-twitter about Facebook, after news that company will start constructing its first datacentre outside the United States, close to the Arctic Circle, in Luleå, Sweden.
The centre will use the frigid l... Read more >
Our new ground-breaking report, The True Cost Of Coal reveals what South Africa's addiction to coal is really costing the country. But beneath all the alarming stats and figures, there is a very real human picture of how coal is affecting So... Read more >
Greenpeace volunteers Mohau, 18, and Allen, 16, give each other a high five for collecting 54 signature for a petition about the use of solar energy. The Jericho project, a solar powered public viewing area for the World Cup, was initiated by Greenpeace Africa, marrying entertainment with education and proving how solar power has to be the solution for South Africa's energy crisis.
© Benedicte Kurzen / Greenpeace
If you thought power cuts from our inadequate centralized energy supply were annoying, imagine if the power were always cut - no light at night, no hot water for dishes or clothes, and no easy heat in winter.
Such is the reality for 2.5 mill... Read more >
361 - 370 of 497 results.


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Holiday Inn El Paso-Airport I-10
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Heading to Tucson
... started acting up. We need to get the RV in to have the furnace checked over in Tucson (before we head home). From Alpine we made a fast getaway and onto El Paso, Tx for 2 nites to rest up before heading to Benson, Az. Benson, Az is, of course desert like and guess what ...windy. Benson, Az is very close to Tombstone so we had to make a quick day trip there to check out the OK Corral. From Benson ...
Three star camping
... ever but sure beat the one we stayed at in Tucson! At least we're not on top of each other and there are trees around.
We're heading to San Antonio today. It is a long haul. Not sure we'll make it there. We'll drive until our asses can't stand it anymore. :-)
West Texas
... etc., go to the register and order from a choice of meat, all weighed and sold by the pound. They put it all in a plastic crate, plus any hot side dishes, and you haul it yourself to a table. Bill got the baby back ribs, and I had a giant baked potato topped with pulled pork, plus a side of green chile stew - we are in Texico, after ...
All alone.
After walking a long time i finally got to a bus station. The police sacred me so i ran to the bathroom. Met a guy who said he would take him to L.A. if I paid him. I left my money in the car. We went to get my money in the lot and the car was ...
Fall of Death Star
... m not a big advocate for abortion, but I sure as hell am not going to side with a party that has clowns advocating legitimate rape and rape babies being G-d's plan...uh...doubt it.
So back to the election. Cousin Blu came over and we anxiously watched the results come in. Unfortunately we don't have cable, so we were unable to watch Faux News and had the TV tuned into something less comical and much more realistic...like PBS. However, ...


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State Rejects Requested Ban on Expanding Irrigation
Farmers in Cochise County lose petition to to stop further development in their area.
Farmers in Cochise County lose petition to to stop further development in their area.
State agency asks for alteration in rule to focus on clear cases of abuse, neglect.
ADOT aims to complete roadwork before next summer
Untreatable Illness has caused severe losses in herds throughout Western states.
Looking for bighorn sheep along the Colorado River; restoring two centuries of history at the San Xavier Mission; what it means to be the first college graduate in your family.
Center works with women/immigrants, teaches how to start and run a business
A postcard from the Desert Bighorn Sheep Workshop from Reporter Vanessa Barchfield
UA scientist contributes to climate change findings
Forecasts show high chance of above-average precipitation for rest of the season
Democrats remain largest voting bloc in county, while independents grow everywhere.
Tribal authority has shut down supply for the rest of this season.
Prosecutors will ask for a sentence of 360 months in prison with credit for time served
Local home values going up near the national historic average
3 million gallons of contamination dumped into waterway that eventually reaches Colorado River.
Arizonans tapping into hundreds of billions of gallons stashed underground as shortage nears.
State Route 89A shut down 30 miles north of Flagstaff after rare tornado, heavy rain hit area.
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text:
HEWVI Wing in Grampound Road
from £1 /night help Price for guests, Nights approx:
from £1 /night help Price for guests, Nights approx:
Estimated nightly price based on a weekly stay. Contact the advertiser to confirm the total cost.
Villa / 1 bedrooms / sleeps 2 Home 196161
Availability Your dates are available
Villa / 1 bedrooms / sleeps 2
|Key Info
Set in a rural location on a working farm, the property faces South West and is a spacious extension of the large farmhouse, with extensive views over the surrounding countryside.
Ideally located for enjoying a relaxing break in Cornwall. The owners live in the main farmhouse, however the property benefits from ample outside space and guest's parking is within their enclosed garden area, therefore privacy is assured. Situated in mid Cornwall, with easy access to both the north and south coasts, offering the fishing villages of Mevagissey and Padstow to name a few as well as many sandy beaches and coves. The area has a variety of attractions including The Eden Project, The Lost Gardens of Heligan, Lands End, the Lizard Peninsula and the popular towns and villages of Falmouth, St Ives and Charlestown with its shipwreck museum. In the evenings, visit one of the local pubs, sit and absorb the view or enjoy a BBQ in the garden.
The accommodation boasts two entrances, one on a slight slope, the other on the level and offers ONE bedroom: with king-size zip-and-link bed which can be a twin on request. Shower room: with large corner shower and WC. Lounge/kitchen/diner: open-plan with woodburner effect electric fire, TV, DVD and Freeview. Kitchen area with electric cooker, small fridge/freezer, washing machine and microwave. french doors lead to the sun lounge with cane furniture, with double doors leading to the garden. Outside: enclosed lawn garden with seating and BBQ,where you can watch the sun set over the distant horizon. Amenities: ample parking. Bed linen, towels, electric and central heating included. 1 small/medium sized dog welcome. Regret no smoking. Location: beach 7 miles, pub and shop 2.5 miles.
The other property at Great Hewas Farm is HEWOL which is approximately 60 metres away..
|Sleeps up to 2, 1 bedrooms
|Car advised
|Family friendly
|Suitable for children over 5
|Pets welcome, No smoking at this property
Features and Facilities
|1 bedroom, 1 bathrooms of which 1 Family bathrooms
|Linen provided
|Private garden
|Not suitable for wheelchair users
|Further details indoors
Downstairs Bedroom
Downstairs Bathroom
|Further details
Working Farm
The Cornwall region
Contact the advertiser for further information about the region.
Contact the advertiser for further details about the local area of this property.
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text:
I didn't realize that TNK was the lien holder on two 2010 VLCC's. Given the borrower's default, it looks like TNK now basically owns them. Not bad I guess. Otherwise report seems to be in line with expectations - which is good.
bluefin, Agree. Looking good.
Don't let shorties steal shares.
Sentiment: Strong Buy
Yes, but do you want to own two more VLCCs? Their rates are terrible.
most likely they will sell them. prob later in the year. market is flooded right now with used VLCCs and newbuilds still coming. Be lucky to get 50 if u had to sell them now. They will sell them to fund the LR2 purchases - i was hoping for a little bit better of a quarter but all in can't complain. depreciation is still running high but the fleet is overvalued on the books anyway imho....
i would say try to get a profitable 1-yr charter then hope for better selling prices
Most likely they will be sold. I did'nt hear the CC. Any info if they will be sold? Prices for 5 year old VLCC's are even now arround USD 55 mill. Source ship2shore.it.
But they might keep them as an Investment. After all the VLCC market is expected to come back in 2015 with no new ship orders untill 2015 or even 16.
True. But they had no choice given the default, and its not like they purchased them. At least they are relatively new ships. Wonder who the defaulter was? - the pr doesn't say.


text: More from SI Report: Dodgers release pitcher Freddy Garcia Report: Dodgers release pitcher Freddy Garcia Marshawn Lynch sports gold cleats for Super Bowl Marshawn Lynch sports gold cleats for Super Bowl Louisville vs. FIU: Game time, live stream, TV coverage Louisville vs. FIU: Game time, live stream, TV coverage Pittsburgh-area high school football player dies after... Pittsburgh-area high school football player dies after... Close Tweet0 Share0 Comment0 Share0 Share0 Stumble It0 Print0 More SI Wire Report: IOC to drop one Summer Olympic sport by Scooby Axson Email Posted: Tue Feb. 12, 2013 Badminton could be on its way out as an Olympic sport. (Michael Regan/Getty Images)The International Olympic Committee will drop one sport from the 2020 Summer Olympics tomorrow, reports the Los Angeles Times. The IOC is prepping for the Sochi Olympics starting next February and the 2016 games in Rio de Janeiro, Brazil. The IOC will decide the host city for the 2020 Summer games in September with Istanbul, Turkey, Tokyo, Japan, and Madrid, Spain vying for the honors.Among the sports reportedly on the chopping block are taekwondo, wrestling, badminton and table tennis and modern pentathlon. Modern pentathlon combines fencing, horse riding, swimming, running and shooting and has been a part of the Olympics since 1912. Taekwondo has been in the Olympics since 2000, wrestling since 1896, badminton since 1992 and table tennis since 1988.The report analyzes more than three dozen criteria, including television ratings, ticket sales, anti-doping policy and global participation and popularity.The last sports removed from the Olympics were baseball and softball, voted out by the IOC in 2005 and off the program since the 2008 Beijing Games.Joining the Olympics at the 2016 Games in Rio de Janeiro will be golf and rugby.The IOC executive board will meet in May to decide which sport or sports to propose for 2020 inclusion. Promoted Stories Comments


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A Law Aimed at Terrorists Hits Legal Immigrants
By LENA WILLIAMS
Published: July 17, 1996
In the three months since a tougher new counterterrorism bill was signed into law, many immigrants who have been living legally in the United States for years have been placed in detention by the Immigration and Naturalization Service and are facing deportation.
Under provisions in the new law, any resident immigrant who is not a naturalized citizen and has been convicted of a crime in the United States, including most felonies and certain misdemeanors, can be detained without appeal and is not eligible for release on bond, according to I.N.S. officials. Many have been arrested as they tried to re-enter the country after trips abroad.
The new Anti-Terrorism and Effective Death Penalty Act, which was signed by President Clinton on April 24 on the one-year anniversary of the Oklahoma City bombing, was part of an omnibus crime package. The law was intended to make it easier to prosecute anyone charged with committing or planning a terrorist attack, and it limited the number of legal appeals for prisoners on death row.
But immigration officials say the law also requires them to detain and deport noncitizens because they have previously been convicted of a crime, no matter how long ago or how minor. Among those being detained are lawful permanent residents -- those who have lived in the country for at least seven years, have married American citizens or have children who are citizens.
In addition, it eliminates the right to apply for a waiver of deportation. Under the previous law, such waivers were granted to "deserving individuals based on their length of residence in the U.S., evidence of rehabilitation and the hardship that their deportation would cause themselves and family members." Immigration officials say that the new law precludes them from issuing waivers and releasing detained residents on bond.
The immigration agency says it has no figures on how many people have been detained or deported under the law. But several immigration lawyers say that based on their caseloads, hundreds of long-term legal residents have been arrested since the law was passed.
The detentions have touched off a heated debate over the Government's interpretation and enforcement of the law. At the time of the signing, President Clinton noted that "this bill also makes a number of major ill-advised changes in our immigration laws having nothing to do with fighting terrorism."
"These provisions eliminate most remedial relief for long-term legal residents," the President warned.
He said he would urge Congress to correct the provisions in legislation, which is now being drafted to address problems in this and other immigration laws.
Lawyers for some detainees concede that the language of the law allows little flexibility in how it is applied. Nevertheless, they say, the immigration agency is being too rigid. They have filed pleas in Federal courts around the nation to prevent the agency from deporting their clients without due process.
"The service has taken the position that the act requires the mandatory detention of any lawful permanent resident who has been convicted of any drug crime, firearms crime and a host of other crimes, regardless of when the convictions occurred," said Judy Rabinovitz, senior staff counsel for the Immigrants' Rights Project of the American Civil Liberties Union.
"The agency is also applying the elimination of discretionary deportation relief to all pending cases, even those in deportation proceedings prior to the enactment of the law," she said. "We believe the Constitution also applies to lawful permanent residents and plan to file appeals on those grounds."
Rigid Language Allows 'Little Choice'
David A. Martin, general counsel of the immigration agency, countered that its officials had not adopted a hard-line approach. "We felt the law and the precedent gave us little choice on some of the positions we've taken," Mr. Martin said.
The law expanded the "grounds of deportability" to cover any drug offense, including marijuana possession, as well as moral turpitude, which in New York State includes crimes like defacing a passport and turnstile jumping. Previously, possession of 30 grams or less of marijuana was not grounds for deportation, nor were acts of moral turpitude committed after five years of entry into the country.
Both sides agree that the new law does not make distinctions between the seriousness of crimes, how long ago the crime was committed or whether the person had served time in prison. As a result, they say only Congress can remedy the situation.
According to Congressional aides, new immigration legislation now being drafted in conference committee restores some discretion on deportation for certain noncitizens, like those who have not committed violent crimes, are not repeat offenders, are longtime residents or are rehabilitated.
Immigration officials say they are working with Congressional leaders to reconcile some of the stricter provisions now in effect with more lenient measures in the previous law.


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What Is Russia's Strategy in Syria and Why Does Egypt Approve?
Why the U.S. Owns the Rise of Islamic State and the Syria Disaster
Harvard's Prestigious Debate Team Loses to New York Inmates
VIDEO: Trevor Noah on Ben Carson's Genius Plans to Deal With Mass Shootings
VIDEO: Gun Logic
Cristina Nehring $10.39
Tom Engelhardt $9.42
Screenshot from KGO-TV
In a letter sent to parents Friday, Piedmont High School Principal Rich Kitchens wrote that the league was set up by a group of the school's varsity athletes, who would secretly "draft" female students and then get points for engaging in sexual activity with them.
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Nobu Hotel Restaurant And Lounge At Caesars Palace Prepares To Open
Parole chiave
General manager of Nobu Hotel Caesars Palace Gigi Vega and chef Nobu... Foto di attualitàArchitettura,Arte, Cultura e Spettacolo,Celebrità,Comparsa,Composizione verticale,Cuoco,Dirigente,Las Vegas,Nevada,Nobu Matsuhisa,Nobu Restaurants,Stati Uniti d'AmericaPhotographer David BeckerCollection: Getty Images Entertainment 2013 David BeckerLAS VEGAS, NV - FEBRUARY 01: General manager of Nobu Hotel Caesars Palace Gigi Vega (L) and chef Nobu Matsuhisa appear during a preview for the Nobu Restaurant and Lounge Caesars Palace on February 1, 2013 in Las Vegas, Nevada. The Nobu Hotel Restaurant and Lounge Casears Palace is scheduled to open on February 4. (Photo by David Becker/Getty Images)


text:
Ruf Set To Introduce Electric Porsche
Vehicles 137 Views
Ruf, widely known for their Porsche aftermarket parts, will show off an all electric vehicle next month based off the 911. At the heart of the vehicle will be an electric motor powered by a lithium-ion battery able to produce 500lb/ft torque and a 125mph top speed. Expected range is said to be 150-180 miles on a single charge.
Other sources say the electric vehicle will be a spin off of the Cayman.
In either case, watch out Tesla!
Pic for demo purposes only
Christen Costa
Grew up back East, got sick of the cold and headed West. Since I was small I have been pushing buttons - both electronic and human. With an insatiable need for tech I thought "why not start a blog focusing on technology, and use my dislikes and likes to post on gadgets."
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Homepage » Product Type » Vehicles » Ruf Set To Introduce Electric Porsche


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Lost Villages, TheI.B.Tauris 2008; US$ 49.00
Across Britain there are more than 3,000 lost villages once-thriving communities that time and fortune.have reduced to ivy-clad remnants and weather-worn ruins. Echoes of a former age, they evoke a natural curiosity as to who lived in them, what caused their decline. Bestselling author Henry Buckton goes in search of some of the Britain?s more recent... more...
Rainbow PieScribe Publications Pty Ltd. 2011; US$ 13.99
Set between 1950 and 1963, this coming-of-age memoir discusses one of America?s most taboo subjects�social class. Combining recollection, accounts, and analysis, this book leans on Maw, Pap, Ony Mae, and other members of this rambunctious Scots�Irish family to chronicle the often-heartbreaking post-war journey of 22 million rural Americans into the... more...
The City, RevisitedUniversity of Minnesota Press 2011; US$ 75.00
The contributors to The City, Revisited trace an intellectual history that begins in 1925 with the publication of the influential classic The City, engaging in a spirited debate about whether the major theories of twentieth-century urban development are relevant for studying the twenty-first-century metropolis. Contributors: Janet Abu-Lughod, Northwestern... more...
Savage Girls and Wild BoysFaber & Faber 2011; US$ 14.57
A compelling history of extraordinary children - brought up by animals, growing up alone in the wilderness, or locked for long years in solitary confinement. Wild or feral children have fascinated us down the centuries, and continue to do so today. Michael Newton deftly investigates such infamous cases as Peter the Wild Boy, who gripped the attention... more...
School According to HumphreyFaber & Faber 2011; US$ 5.82
Join much-loved Humphrey for a new adventure in his phenomenally successful series! more...
Cracking the Freemason's CodeEbury Publishing 2011; US$ 19.18
In Cracking the Freemason's Code, Robert Cooper explains exactly who the Freemasons are and what they do. As the Curator of the Scottish Masonic Museum and Library, the author is in a unique position to reveal the secret history of this elect brotherhood. Prompted by growing public interest and provoked by the controversial stories that circulate... more...
Child Migration in AfricaZed Books 2011; US$ 39.95
Child Migration in Africa explores the mobility of children without their parents within West Africa. Drawing on the experiences of children from rural Burkina Faso and Ghana, the book provides rich material on the circumstances of children's voluntary migration and their experiences of it. Part of the groundbreaking Africa Now series, Child Migration... more...
British UntouchablesAshgate Publishing Ltd 2013; US$ 149.95
Dalits, formerly called 'untouchables', remain the most oppressed community in India, and indeed in South Asia and have, until recently, been denied human and civic rights. On emigration to the UK and other Western countries they faced a double disadvantage: caste discrimination and racial discrimination from 'white' society. However, in the late... more...
Linguistic Landscape in the CityChannel View Publications 2010; US$ 49.95
This book focuses on linguistic landscapes in present-day urban settings. In a wide-ranging collection of studies of major world cities, the authors investigate both the forces that shape linguistic landscape and the impact of the linguistic landscape on the wider social and cultural reality. Not only does the book offer a wealth of case studies and... more...
Redefining RetirementOxford University Press 2007; US$ 119.99
As the leading edge of the 'Baby Boom' generation attains age 60, members of this unusually large cohort born 1946-66 are poised to redefine retirement - just as they have restructured educational, housing, and labor markets in prior days. Looking ahead, their numbers and energy are sure to have a major impact on national pensions, healthcare,... more...


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Hat tip: First Showing
Zero Dark Thirty TV Spot
6 comments
Aragorn 3 years ago
Seeing Jennifer Lawrence as the frontrunner with no significant competitions was turning to be boring. I am glad that now at least we have a significant competition, if not a possible winner. Jessica Chastain is a very good actress imho. I liked her performance even better than Olivia Spencer's in the Help. And she has been consistently good in everything else she did (I didnt see her on Broadway stage, but that's a different platform, and this is Oscars' not Tonys).Like Dislike
Aragorn 3 years ago
Oops, I forgot to add that I wouldnt mind seeing her win Oscar this year, especially if she is as good as many people, including Sasha, already mentioned and she carries the entire movie with her strong character. That's the kind of female character that I like to see win.Like Dislike
VVS 3 years ago
Aragorn, some of us with a rational mind knew that Lawrence had little of a chance regardless of what the blogs were sayingLike Dislike
SallyinChicago 3 years ago
Message to Hollywood: There are just too many "good" movies coming out in the next month and the Academy is when — January? So how about you guys do what Arbitrage and Butter did? Offer these movies in the theater AND online. That way we can see them at our leisure. And FF and repeat the movie if we want.
I can't stand this bunching of the Academy movies in one month. Who has time to sit through 2-1/2 hours?Like Dislike
Aragorn 3 years ago
WS: I dont think J.Law had/has a little chance. She seems still strong but now she has a strong competitor as well.
Sally, I second that. If you ever start an email campaign or petition let me know:)Like Dislike
Munro202 3 years ago
My god, I am so damn excited for this film.Like Dislike


text:
No, Amber Rose and Blac Chyna aren't getting a reality show — and it has nothing to do with Kim Kardashian.
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Page 1
American Journal of Epidemiology
ª The Author 2011. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of
Public Health. All rights reserved. For permissions, please e-mail: firstname.lastname@example.com.
Vol. 174, No. 4
DOI: 10.1093/aje/kwr115
Advance Access publication:
June 14, 2011
Original Contribution
Aspirin Use, Body Mass Index, Physical Activity, Plasma C-Peptide, and Colon
Cancer Risk in US Health Professionals
Xuehong Zhang*, Stephanie A. Smith-Warner, Andrew T. Chan, Kana Wu, Donna Spiegelman,
Charles S. Fuchs, Walter C. Willett, and Edward L. Giovannucci
* Correspondence to Dr. Xuehong Zhang, Channing Laboratory at Landmark Center (West Wing), 401 Park Drive, Boston,
MA 02115 (e-mail: email@example.com).
Initially submitted September 8, 2010; accepted for publication March 16, 2011.
Aspirin use decreases colon cancer risk, but this association may vary among population subgroups. The
aspirin-colon cancer association was evaluated according to body mass index and physical activity in 1,701
incident colon cancer cases diagnosed during follow-up of 139,310 participants for up to 26 years in 2 US pro-
spective cohort studies that began in 1980 and 1992, respectively. Whether plasma C-peptide levels modified the
association was examined by using a nested case-control design (n ¼ 384 cases, 749 controls). Multiplicative and
additive interactions were tested. Body mass index did not modify the association; pooled multivariable relative
risks for regular aspirin use versus nonuse ranged from 0.74 to 0.75 in the normal weight and obese groups (test for
multiplicative interaction, P ¼ 0.75; test for additive interaction, P ¼ 0.66). Pooled multivariable relative risks for
regular aspirin use were 0.86 (95% confidence interval (CI): 0.66, 1.11) in the low and 0.67 (95% CI: 0.58, 0.77) in
the high physical activity groups with no interaction evident on either the multiplicative or additive scale (P > 0.10).
Plasma C-peptide levels also did not modify the aspirin-colon cancer association, with multivariable relative risks
of 0.74 (95% CI: 0.50, 1.10) for the low and 0.65 (95% CI: 0.46, 0.92) for the high group. Reductions in colon cancer
risk associated with aspirin use were not significantly modified by body mass index, physical activity, or plasma
C-peptide level in this study.
additive model; aspirin; body mass index; cohort studies; colonic neoplasms; C-peptide; motor activity; multiplica-
tive model
Abbreviations: BMI, body mass index; CI, confidence interval; COX-2, cyclooxygenase-2; HPFS, Health Professionals Follow-up
Study; MET, metabolic equivalent task; NHS, Nurses' Health Study; PGE2, prostaglandin E2.
Colorectal cancer is the third most commonly occurring
cancer in both men and women in the United States (1).
studies each have shown that aspirin use reduces the inci-
dence of colorectal cancer, particularly for high doses used
for a long duration (2–9). Despite this beneficial effect, as-
pirin use has associated side effects including peptic ulcers
and gastrointestinal bleeding (8, 10), and widespread use
is not recommended for preventing colorectal cancer for
individuals at average risk for colorectal cancer (10). How-
ever, the benefits of aspirin use may outweigh the potential
risks among individuals at increased risk of developing
colorectal cancer.
Obese or physically inactive individuals are at higher
risk of developing colorectal cancer compared with normal
weight and physically active individuals (11, 12), possibly
because the former have higher prostaglandin E2(PGE2)
concentrations (13). Elevated PGE2levels result in activa-
tion of cell proliferation, angiogenesis, invasion, and inhi-
bition of apoptosis (14). Aspirin has been hypothesized to
decrease colorectal cancer risk through the inhibition of
cyclooxygenase-2 (COX-2)-mediated synthesis of PGE2
(15, 16). Overweight individuals are at higher risk of colon
cancer (17) and also have been shown to have an increased
459Am J Epidemiol. 2011;174(4):459–467
Page 2
has been observed to be effective in preventing the recur-
rence of colorectal adenomas, precursor lesions of colo-
rectal cancer (19), in obese individuals only (20). We thus
hypothesized that the inverse association between aspirin
use and colon cancer risk would be stronger among obese
or physically inactive individuals compared with normal
weight and physically active individuals. We examined this
hypothesis in the Nurses' Health Study (NHS) and the
Health Professionals Follow-up Study (HPFS) in which par-
ticipants provided detailed and updated data on aspirin use
every 2 years. Given that approximately 70%–80% of colo-
rectal cancer in developed countries is colon cancer (21) and
that the associations with aspirin use, body mass index, and
physical activity are stronger for risk of colon cancer than
rectal cancer (21, 22), we focus on colon cancer in this
report. This study extends findings (2–5) of inverse asso-
ciations between aspirin use and risk of colon cancer in
earlier analyses in the same cohorts by providing additional
follow-up and conducting interaction analyses to examine
new hypotheses.
Although the COX-2 pathway is the major proposed
underlying pathway to explain the observed inverse associ-
ation between aspirin use and colon cancer risk, aspirin has
also been hypothesized to alter colon cancer risk by other
pathways includingtheinsulin-relatedpathway(23).Obesity
and physical inactivity are 2 determinants of hyperinsuline-
mia (24), and aspirin reverses hyperinsulinemia in obese
rodents (25).We thus testedwhetherthe aspirin-colon cancer
association differed by plasma concentrations of C-peptide,
a validated marker for insulin secretion (26).
Study population
The NHS is a prospective cohort of 121,700 registered
female nurses who were aged 30–55 years at baseline in
1976 in the United States. The HPFS is a prospective cohort
study of 51,529 US male professionals who were aged
40–75 years at baseline in 1986. Participants in both stu-
dies have been mailed questionnaires every 2 years since
baseline to collect data on demographics, lifestyle factors,
medical history, and disease outcomes. The follow-up rate
has been greater than 90% for both cohorts. These studies
have been approved by the institutional review board at the
Brigham and Women's Hospital, Boston, Massachusetts.
Identification of incident colon cancer cases
Participants in both cohorts reported cancer and other
disease outcomes on the biennial questionnaires. Re-
searchers were given permission by the study participants
to obtain medical records and pathology reports on colon
cancer. Researchers, blinded to exposure information, re-
viewed the medical records to abstract information on
anatomic location, stage, and histologic type of the cancer.
The International Classification of Diseases, Ninth Revision
(27), was used to define colon cancer by codes 153.0–153.4
and 153.6–153.9. The National Death Index (28) was used
to identify deaths among nonresponders.
Ascertainment of colon cancer controls in the nested
case-control study
A nested case-control data set was created among par-
ticipants who provided a blood sample. Detailed informa-
tion on blood draw, transportation, and storage is reported
elsewhere (29, 30). In brief, blood samples were collected
from 32,826 NHS participants between 1989 and 1990 and
from 18,225 HPFS participants between 1993 and 1995.
The data set included incident colon cancer cases from
1990 to June 2004 in the NHS and from 1994 to January
2002 in the HPFS. We excluded participants with a previous
cancer diagnosis (except nonmelanoma skin cancer). We
further excluded participants with diabetes before blood
draw because plasma C-peptide concentrations may not
represent long-term insulin secretion among diabetic pa-
tients. Controls were matched 2:1 to colon cancer cases on
age and year and month of blood donation, and, in the NHS
only, on fasting status. Controls were alive and cancer free
at the time of the diagnosis of the cases.
Assessment of aspirin use
Information on aspirin assessment has been reported
in detail elsewhere (2–5). Briefly, in the NHS, information
on aspirin use was first obtained in 1980 and every 2 years
thereafter except in 1986. In 1980, participants were asked
whether they currently took aspirin in most weeks and, if
yes, answered questions on the number of aspirin taken
per week and years of aspirin usage. In 1982, 1984, and
1988, the average number of aspirin tablets usually taken
per day was asked. In 1990 and 1992, the average number
of days per month of aspirin use was asked; information
on the number of tablets taken per day was not obtained.
For these 2 years, we assumed that 1 standard aspirin tablet
(325 mg) was taken per day on the basis of a supplementary
questionnaire sent to 4,238 participants (31). Beginning
in 1994, the average number of tablets taken per week
and the frequency of use were assessed. We calculated
the duration in 1986 in the NHS by the information col-
lected in 1984. In the HPFS, in 1986 and every 2 years
thereafter, participants were asked whether they used as-
pirin 2 or more times per week. Beginning in 1992, the
amount of aspirin taken and the frequency of use were as-
sessed. For both cohorts, information on low dose (''baby'')
aspirin was not available until year 2000. However, par-
ticipants were specifically asked in their biennial surveys
to convert intake of 4 baby aspirin to 1 standard tablet
aspirin before entering their responses. Thus, aspirin dose
in our analysis accurately reflected standard tablet (325
mg) equivalents.
Assessment of anthropometric variables
Height was obtained by self-report in the NHS in 1976
and in the HPFS in 1986. Weight was obtained by self-
report at baseline and in subsequent biennial questionnaires
in both studies. The age-adjusted correlation coefficients
between self-reported weight and measured weight were
0.96 for the NHS (32) and 0.97 for the HPFS (32).
460Zhang et al.
Am J Epidemiol. 2011;174(4):459–467
Page 3
Assessment of physical activity
Recreational or leisure-time physical activity was asked
in the questionnaires in both the NHS and the HPFS. Start-
ing from 1986 in the NHS, participants reported their av-
erage time engaged in the following activities: walking or
hiking outdoors, jogging, running, bicycling, lap swimming,
tennis, calisthenics/aerobics/aerobic dance/rowing machine,
and squash/racquet ball. Additionally, participants reported
the number of flights of stairs climbed daily and their usual
walking pace. The same questions were asked in subsequent
biennial questionnaires with minor modifications. Similar
questions were used in the HPFS starting in 1986. We
derived the metabolic equivalent task (MET)-hour score
(MET-hours/week) for each activity by multiplying the time
spent for that activity group each week (hours/week) and
its typical energy expenditure requirements expressed in
MET values. The total MET-hour score was calculated as
the sum of the values of each activity. The validity of the
questionnaire-based physical activity assessment has been
tested in the NHS II, a similar cohort of younger nurses (33),
and in the HPFS (34). The correlation between reported
physical activity on the questionnaire and that recorded in
4-week diaries was 0.62 in the NHS II (33). The correlation
betweenvigorous activity and resting pulsewas ?0.45 in the
Measurement of plasma C-peptide
The detailed lab assays on plasma C-peptide have been
reported elsewhere (29, 35). In brief, plasma C-peptide was
assayed by using an enzyme-linked immunosorbent assay in
the laboratory of Dr. Michael Pollak. Samples from matched
case-control sets were handled together and assayed in the
same batch along with randomly inserted masked quality
control samples. All laboratory personnel were blinded to
case, control, and quality control status. The mean intra-
essay coefficient of variation from quality control samples
was less than 13%.
Statistical analyses
We treated 1980 as the baseline for the NHS and 1992
as the baseline in the HPFS (unless otherwise noted), be-
cause the number of tablets of aspirin used per week was
first measured at these times. We excluded participants with
a history of cancer (except for nonmelanoma skin cancer),
ulcerative colitis, Crohn's disease, and familial adenoma-
tous polyposis at baseline.
Because the current analyses extended findings from pre-
vious analyses of the same cohorts (2–5), to be consistent,
we defined regular aspirin users as those participants who
reported taking 2 or more standard (325 mg) tablets of
aspirin per week. We further evaluated the dose and the
duration of aspirin used. Body mass index was classified
into 2 categories: normal weight (body mass index (BMI),
18.5–24.9 kg/m2) and overweight/obese (BMI, ?25 kg/m2).
Physical activity was also classified into 2 levels (low and
high) by using different cutpoints for men and women be-
cause of the difference in reported physical activity levels in
the 2 studies. Because the information on aspirin use, body
mass index, and physical activity was updated on almost
every follow-up cycle, we modeled these as time-varying
variables to take into account changes over time.
The person-time for each participant was calculated
from the date of baseline questionnaire return to the date
of death, loss to follow-up, colon cancer diagnosis, or the
end of follow-up (June 1, 2006, for women and January 31,
2006, for men), whichever came first. In each study, we used
the Cox proportional hazards model (36) to calculate rela-
tive risks and 95% confidence intervals and adjusted simul-
taneously for age (in months) and year of questionnaire
return using SAS PROC PHREG (37).
We then conducted multivariable analyses in men and
women separately (refer to Table 2 for the list of confound-
ing variables). We used the most updated information for
all covariates prior to each follow-up cycle. The trend tests
across categories of aspirin dose and duration were per-
formed by assigning median values of these categories
and entering these values as continuous terms in the model.
We investigated whether the associations between aspirin
use, dose, and duration and colon cancer risk differed be-
tween women and men by using the Q statistic (38, 39),
which follows an approximate v2distribution with 1 df.
We pooled the results using a random effects model (39,
40), because there was no statistically significant between-
studies heterogeneity.
We examined whether the association between aspirin
use and colon cancer risk varied by plasma C-peptide using
a nested case-control design. These analyses included 384
incident cases (217 in the NHS and 167 in the HPFS) and
749 controls (419 in the NHS and 330 in the HPFS). We
categorized plasma C-peptide levels into a binary variable
using the medianvalues specific to the control group in each
cohort. We merged the NHS and HPFS data sets into 1 data
set because of the relatively small number of cases who used
aspirin in each cohort within each plasma C-peptide group
(n ? 50 cases). We recategorized duration of aspirin use into
2 groups (0–5, ?6 years of use) because no cases occurred
in the ?11-year group in the HPFS.
We evaluated whether the associations with aspirin use
differed by body mass index, physical activity, and plasma
C-peptide levels using multiplicative and additive interac-
tion analyses. We focused on regular aspirin use in the in-
teraction analyses because we had limited power to look at
details of dose and duration. To evaluate the multiplicative
interaction, we constructed a cross-product term between
aspirin use and body mass index, physical activity, or
C-peptide level and used a Wald test to examine whether
the coefficient was statistically significant. For the analyses
evaluating whether plasma C-peptide modified the aspi-
rin association, we used unconditional logistic regression
For the additive interaction analyses, we calculated the
Synergy Index (S) (41), relative excess risk due to interac-
tion (renamed as ''interaction contrast ratio'' later on), and
programs developed by Lundberg et al. (43) and Andersson
et al. (44) to conduct the analyses by creating cross-classified
variables between aspirin use and the potential effect
Aspirin Use and Colon Cancer Risk by Population Subgroup461
Am J Epidemiol. 2011;174(4):459–467
Page 4
modifier modeled as a binary variable. The delta method
(45) was used to derive the 95% confidence intervals for
each measure. Given that the study-specific results were
similar for these 3 measures, we present only S in our tables.
All statistical analyses were 2 sided, and P < 0.05 was
considered statistically significant. We conducted all analy-
ses using SAS, version 9, software (SAS Institute, Inc.,
Cary, North Carolina).
In the NHS, 1,253 incident colon cancer cases were doc-
umented among 104,607 women during 2,537,286 person-
years from 1980 to 2006. In the HPFS, 448 incident cases of
colon cancer were documented among 34,703 men during
441,295 person-years from 1992 to 2006. Regular aspirin
users were comparable to nonregular aspirin users in terms
of age, body mass index, family history of colorectal cancer,
alcohol consumption, physical activity level, and intake of
folate, calcium, beef, pork, or lamb as a main dish and
processed meat; in contrast, regular aspirin users were
slightly more likely to use multivitamins and to smoke
(Table 1). In addition, approximately 30%–40% of the par-
ticipants were regular aspirin users in each 2-year follow-up
period with a slightly increasing consumption trend ob-
served in more recent follow-up (data not shown).
Because the age- and multivariable-adjusted results for
aspirin use, dose, and duration were similar for the total
study population, we present only the multivariable results
(Table 2). As reported previously in these cohorts for a
shorter follow-up period (2–5), aspirin use was associated
with a statistically significant lower riskof coloncancer with
significant inverse dose-response relations being observed
for both increasing aspirin dose and duration (Table 2).
The results of aspirin use on colorectal cancer were similar
Table 1.
Professionals Follow-up Study (1992)
Baseline Characteristics of the Nurses' Health Study (1980) and the Health
Nurses' Health
(n 5 104,607)
Health Professionals
Follow-up Study
(n 5 34,703)
Not Regular
Regular Usersa
Not Regular
Regular Usersa
Mean% Mean% Mean% Mean%
Age, years46.646.5 58.060.1
Body mass index,
24.424.825.6 26.0
Physical activity,
14.413.4 36.836.5
History of colorectal
cancer in a
parent or sibling
68 1312
Former or current
505848 54
67 10 11
Multivitamin use2338 3848
Total calcium
intake, mg/dayd
Total folate
intake, lg/dayd
361371 486 526
Beef, pork, or lamb
as a main dish,
2.5 22.214.171.124
Processed meat
1.1 1.2 1.21.1
Abbreviation: MET, metabolic equivalent task.
aRegular aspirin use was defined as consumption of 2 or more 325-mg tablets per week.
bBody mass index was calculated as follows: weight (kg)/height (m)2.
cFor the Nurses' Health Study, 1986 data were used. MET-hours ¼ sum of the average time/
week spent in each activity 3 MET value of eachactivity; 1 MET, the energy spent sitting quietly, is
equal to 3.5 mL of oxygen uptake per kilogram of body weight per minute for a 70-kg adult.
dNutrient values for calcium and folate were the energy-adjusted intake from foods and sup-
462Zhang et al.
Am J Epidemiol. 2011;174(4):459–467
Page 5
according to median age of diagnosis. Also consistent with
previous analyses of the same cohorts (11, 12), the present
analysis showed positive associations with higher body
mass index, low physical activity, and increased levels of
plasma C-peptide for both men and women (data not
index level, the pooled multivariable relative risks comparing
regular aspirin use versus nonuse were 0.74 (95% confi-
dence interval (CI): 0.63, 0.87) for the normal weight group
and 0.75 (95% CI: 0.60, 0.93) for the overweight/obese
group (Table 2; test for multiplicative interaction, P ¼ 0.75).
In addition, when we categorized body mass index into 3
groups, the risk estimates were similar for normal weight
(BMI,18.5–24.9 kg/m2), overweight (BMI,25–<30 kg/m2),
and obese (BMI, ?30 kg/m2) strata (data not shown). There
also was no evidence of an additive interaction; the synergy
index was close to 1.0 (S ¼ 1.12, 95% CI: 0.69, 1.81; test
for additive interaction, P ¼ 0.66).
The association with regular aspirin use was not signifi-
cantly modified by level of physical activity, although the
strongest inverse association for regular aspirin use was
observed in the more physically active group (test for mul-
tiplicative interaction, P ¼ 0.47) (Table 3). Similarly, no
significant additive interaction was observed between aspi-
rin use and physical activity (S ¼ 0.67, 95% CI: 0.41, 1.10;
test for additive interaction, P ¼ 0.11).
We present the results adjusted for the matching factors
only for the analyses by plasma C-peptide, because the re-
sults adjusted for the matching factors (i.e., season of blood
draw, fasting time) were similar to the multivariable results
and were more precise. The risk of colon cancer comparing
regular aspirin users versus nonusers was similar in the
low (multivariable relative risk ¼ 0.74, 95% CI: 0.50,
Table 2.
(kg/m2) in the Nurses' Health Study (1980–2006) and the Health Professionals Follow-up Study (1992–2006)
PooledaMultivariable Relative Risks of Colon Cancer According to Aspirin Use by Body Mass Index
Total Study Population
(n 5 139,310)
Stratified by BMIb
Normal Weightc
No. of
No. of
No. of
Regular usee
No 1,1121 Referent 5481 Referent5641 Referent
Yes 589 0.730.66, 0.81 2470.74 0.63, 0.873420.75 0.60, 0.93
Dosage, no.
of tablets/week
0–<2 1,1121 Referent5481Referent 5641 Referent
2–5 3100.75 0.66, 0.851360.76 0.63, 0.93 1740.76 0.64, 0.91
?6 2790.71 0.62, 0.82 1110.72 0.58, 0.89 1680.74 0.55, 0.99
Duration, years
of regular use
0–51,2321 Referent5981Referent 6341Referent
6–10 2110.81 0.70, 0.94 760.70 0.51, 0.971350.88 0.72, 1.07
?112580.69 0.60, 0.801210.76 0.62, 0.941370.66 0.52, 0.84
Abbreviations: BMI, body mass index; CI, confidence interval; HPFS, Health Professionals Follow-up Study; MET,
metabolic equivalent task; NHS, Nurses' Health Study; RR, relative risk.
aA random effects model was used to pool the results. No statistically significant heterogeneity was observed
between men and women.
bFor multiplicative interaction analyses, a Wald test was used to test the beta-coefficients of the cross-product
terms between regular aspirin use and BMI (P ¼ 0.75). For additive interaction analyses, we calculated the Synergy
Index as S ¼ 1 under the null hypothesis of no additive interaction. For the test for additive interaction, S ¼ 1.12 (95%
cNormal weight was defined as BMI ¼ 18.5–<25 kg/m2; overweight/obese was defined as BMI ?25 kg/m2.
dMultivariable relative risks were adjusted for age (in months), smoking before age 30 years (0, 1–4, 5–10, or >10
pack-years), history of colorectal cancer in a parent or sibling (yes or no), history of endoscopy (yes or no), current
multivitamin use (yes or no), consumptionof processedmeat (quintiles),consumption of beef, pork, or lamb asa main
dish (quintiles), alcohol consumption (0–<5, 5–<10, 10–<15, 15–<30, or ?30 g/day), energy-adjusted total folate
(quintiles) and total calcium (quintiles) intake, physical activity (<6, ?6 MET-hours/week for NHS; <15, ?15 MET-
hours/week for HPFS), and postmenopausal hormone use (premenopausal, never, past, or current user) in the NHS
only. BMI (<25, ?25 kg/m2) was adjusted in the total study population.
eRegular aspirin use was defined as consumption of 2 or more 325-mg tablets per week.
Aspirin Use and Colon Cancer Risk by Population Subgroup 463
Am J Epidemiol. 2011;174(4):459–467


text:
Dustin McCombs didn't appreciate being named "Creep of the Week" by the Jefferson County (AL) Sheriff's Office, so he stopped by their Facebook page to give them a piece of his mind.
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On August 29-September 1, automotive aficionados have the opportunity to get behind the wheel of an exotic supercar such as a Porsche 911/997, Lamborghini LP560, Audi R8, or Ferrari F430. All of the cars have automatic transmissions with paddle shifts. Both options begin with a quick instruction on racing fundamentals and safety overviews for the vehicles and the course. After the short class, drivers slap on a helmet and prepare for the Pike's Peak International Raceway. A professional driver is also available to take passengers for a high-speed ride-along, ideal for those 10 and up who want to experience the thrill of the supercars. For additional fees, drivers can also take home two 5"x7" photographs of themselves getting into and driving the car, as well as in-car high-definition video footage of the entire drive.
Xtreme Xperience
Xtreme Xperience, one of the nation's premier supercar driving experiences, was founded by a group of car enthusiasts. Their mission is to make the world's best exotic cars accessible for everyone to enjoy as they should be – on real racetracks across the U.S. Since their first event in 2012, Xtreme Xperience has helped more than 50,000 people cross "drive an exotic car" off their bucket lists. Xtreme Xperience provides a safe, educational, and accessible approach for drivers and passengers who wish to experience the thrill of driving the some of the world's most exclusive cars, including the Ferrari 458 Italia, Lamborghini LP560-4, Porsche 911 GT3, Audi R8 V10, Nissan GT-R, and more. Hosting 30 events at 20 racetracks, Xtreme Xperience and their world-class fleet can be found at racetracks nationwide.
95% of 216 customers recommend
"Purchase the discovery lap And the video is woth the money as well"
"Do the lead car ride along FIRST so that you can get a feel for the track BEFORE you get your turn at driving your car!"
"Worth every penny! The "lead lap" makes the driving laps so much more fun. Everything about the experience was first class."
Pikes Peak International Raceway
16650 Midway Ranch Rd
Fountain, CO 80817
+18662737727Get Directions