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Press Release |
AHF: Gilead`s Record 76% Profit Margin Squeezes Taxpayer-Funded AIDS Programs
* Reuters is not responsible for the content in this press release.
http://pdf.reuters.com/htmlnews/8knews.asp?i=43059c3bf0e37541&u=urn:newsml:reuters.com:20130117:nBw176572a Gilead Sciences (GILD), makers of Stribild - the most expensive first line combination AIDS therapy on the market today at $28,500 per patient, per year - has outpaced industry averages in revenue growth and gross profit margin by gouging the prices of combination AIDS therapy treatments that are paid for by government programs Exploitation of Medicare, Medicaid, and other programs drives up healthcare costs and keeps patients out of care - as patents on several Gilead drugs are set to expire and the company hiked the prices of four HIV/AIDS medications by an average of 6% on Jan. 1, AIDS Healthcare Foundation (AHF) reaffirms its demand that Gilead lower its drug prices WASHINGTON--(Business Wire)-- According to a stock buy recommendation from New York-based stock analyst group TheStreet Ratings released this week, pharmaceutical giant Gilead Sciences (GILD) shows first quarter earning increases compared to this time last year across the board that exceed industry averages by a large margin. Leading global nonprofit AIDS Healthcare Foundation (AHF) contends these record earnings come at the expense of patients who cannot access treatment for HIV/AIDS due to Gilead`s price gouging. TheStreet reported Gilead`s closing stock price has jumped 76.13% compared to its closing price one year ago, and the group expects the price to rise even higher. Additionally, the group said Gilead`s gross profit margin is "currently very high" at 76.90%, another increase from the same quarter last year. Additionally, the company`s net profit margin of 27.83% exceeds industry averages. Gilead`s revenue growth was up 14.4% from this time last year and again outpaces the industry average growth of 5.4%. "AHF has repeatedly criticized Gilead and its CEO John Martin - whose income last year was $54 million - for price gouging on its HIV/AIDS treatments, an action that places the drugs out of reach for many patients due to increases in healthcare costs trickling down to government programs and insurers such as Medicare and Medicaid as well as private insurers and programs like the AIDS Drug Assistance Program," said Michael Weinstein, President of AIDS Healthcare Foundation. Stribild, Gilead`s four-in-one combination pill that was approved by the Food and Drug Administration in early September of last year, is the most expensive AIDS first line treatment on the market today at $28,500 per patient, per year, which was 35% higher than the price of their best-selling treatment at that time and is more than most HIV/AIDS patients earn annually. Already this year, on January 1, Gilead raised the prices of four key AIDS medications by an average of 6%, including the price of Atripla, its best-selling three-in-one combination treatment, the price of which was increased by 6.9% to a Whole Acquisition Cost (WAC) of $1,878.23 per patient, per month. The other three HIV/AIDS medications that saw price hikes are Complera, which was raised by 5.8% to a WAC of $1,936.53; Emtriva, by 5.5% to a WAC of $478.45; and Viread, by 6% to a WAC of $771.39. A new study released this week in the Annals of Internal Medicine compared the potential economic savings of using generic antiretroviral treatment instead of branded medication like Atripla to the possible reduction in drug efficacy, caused largely by the increase in pill burden that threatens to knock patients off their medical regimen with missed doses. Though the study found the increased pill burden - requiring patients to take two or three pills daily instead of the all-in-one combinations sold by Gilead - could lead to a potential loss of 4.4 months of life per patient per lifetime, the projected economic savings exceeded a billion dollars in annual healthcare costs. The more affordable generic treatment options are the same medications that have been keeping people living with HIV/AIDS alive in Africa and developing countries like India for decades, as pointed out by AHF President Michael Weinstein in a press statement earlier this week. "The savings could be as much as one billion dollars per year here in the United States, while the efficacy decreased relatively slightly when using generics," Weinstein said. "Now that Gilead`s patents on many key drugs are expiring, the company must lower its prices of drugs like Atripla, Stribild-a four-in-one combination that actually relies on several older Gilead drugs that were otherwise approaching end of patent. In addition, we strongly believe that local, state, and federal governments should use every tool at their disposal to bring down drug prices. As tax dollars ultimately pay for most of these drugs, we extend our call on Gilead for price concessions on these AIDS drugs." About AIDS Healthcare Foundation AIDS Healthcare Foundation (AHF), the largest global AIDS organization, currently provides medical care and/or services to more than 183,000 individuals in 28 countries worldwide in the US, Africa, Latin America/Caribbean, the Asia/Pacific Region and Eastern Europe. To learn more about AHF, please visit our website: www.aidshealth.org, find us on Facebook: www.facebook.com/aidshealth and follow us on Twitter: @aidshealthcare. AIDS Healthcare Foundation Ged Kenslea, +1-323-308-1833 mobile: 323-791-5526 email@example.com or Kyveli Diener, +1-323-308-1821, ext. 1805 mobile: 310-779-4796 firstname.lastname@example.com Copyright Business Wire 2013
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It is no secret that divorces are expensive. Between hiring separate attorneys and dividing assets, to starting over again with a single income, the cost of divorce has increased in the past few years. While divorces are expensive for the parties involved, there are implications for the economy as well. In recent studies, there has been a significant link between divorce rates and economy health. Here is a look at how divorce can directly impact the economy, and where the divorce rate stands today.
Divorce Slows Economic Growth
There are few things than can slow economic growth quite like a high rate of divorce. According to a study performed by the Marriage and Religion Research Institute, marriage is an important contributor to economic growth. Healthy marriages have been proved to promote economic growth, while divorce adversely impacts the economy. Another factor that affects economic growth is the increase of total households. When couples are divorced, more housing, power and resources are required. The more the divorce rate increases, the more adverse the affect on the economy.
Changing Family Formula Driving Down Divorce Rates
A commonly-quoted statistic regarding the topic of divorce is "The divorce rate in the United States is 50% of all marriages." While this information has become common knowledge, is it accurate? It turns out that statement isn't as accurate or telling as the truth itself. Divorce rate is calculated for a number of different groups divided by age, whether this is the person's first marriage, gender and more. The average divorce rate in the U.S. for a first marriage is actually 41%, according to Divorcerate.org. While the average may have been higher at another time, there are some significant factors that may be driving down the average divorce rate in the U.S.
Changing family formulas and dynamics certainly come into play when considering the drop in the divorce rate. Women are largely becoming the breadwinners of their families. It appears the divorce rate is dropping as dual-income families become the norm. Another important aspect of a lower divorce rate is the older average age at which people are now getting married. According to an article written by CNBC.com in March 2012, the average age in 2009 for men to marry was 28, and for women, 26. This is a far cry from the average ages in 1950, which were just 23 for men, and 20 for women. While the divorce rate remains high, it has slightly improved over recent years, and this is believed to a result of people waiting to marry, as well as modernized family restructuring.
How the Divorce Revolution Impacts Growth
With the divorce rate being so high, it has negatively affected America's potential for economic growth. According to an article written by BusinessNewsDaily.com in March 2012, there is no equivalent byproduct of policy change that can wreak havoc on a country's economy quite like the divorce revolution can. Divorce not only affects the individuals involved, it can also deeply hinder a country's ability to climb out of a recession and improve economic growth.
The Bottom Line
While the divorce rate in the U.S. has certainly decreased in recent years, divorce continues to play its part in dragging down the country's economy. With divorce comes the need for more housing, energy, transportation and other important resources. If the changing family dynamic continues to improve divorce statistics, the U.S. may experience the financial benefits that come from a healthy marriage - financial stability over a long period of time.
Personal Finance
Avoid These 5 Financial Mistakes in a DivorceTo ensure you get what's rightfully your's in a divorce, avoid these financial mistakes.
Calculating Cross Elasticity of DemandCross elasticity of demand measures the quantity demanded of one good in response to a change in price of another.
Social Security and Divorce: A GuideRetirement for divorced individuals can be more complex. Here's how to navigate Social Security benefits.
Personal Finance
Divorce Planning Checklist: What You Need to KnowDivorce can be costly and hard if you don't plan for it. Making sure you have all your ducks in order will go a long way in easing the pain.
Explaining Fair Market ValueFair market value is the price at which a buyer and seller are willing to exchange a good.
Understanding Production EfficiencyProduction efficiency is the point at which an economy cannot increase output of a good or service without lowering the production of another product.
What Does Short Run Mean?Short run is the concept that for a business, at least one factor of production is fixed while others are variable.
Did the Fed Miss its Window to Raise Rates?The debate in the media over whether the Federal Reserve will announce liftoff this month or in December continues to rage on.
What's a Price Ceiling?A price ceiling is the maximum amount a seller can charge for a product or service.
Explaining IndustryThe term industry refers to a classification of companies that share similar business activities.
How does divorce affect Social Security benefits?If you are eligible to receive Social Security retirement benefits on your own account, your marital status has no impact ... Read Full Answer >>
How are Social Security benefits calculated for divorced spouse?The maximum Social Security retirement benefit payable to a divorced spouse is 50% of the amount that would be paid to the ... Read Full Answer >>
Can a divorced woman collect Social Security from her ex-husband?While a number of conditions must be met, a divorced woman is able to collect Social Security benefits through her ex-husband. ... Read Full Answer >>
What is the utility function and how is it calculated?In economics, utility function is an important concept that measures preferences over a set of goods and services. Utility ... Read Full Answer >>
What does marginal utility tell us about consumer choice?In microeconomics, utility represents a way to relate the amount of goods consumed to the amount of happiness or satisfaction ... Read Full Answer >>
What is the difference between JIT (just in time) and CMI (customer managed inventory)?Just-in-time (JIT) inventory management focuses solely on the need to replenish inventory only when it is required, reducing ... Read Full Answer >>

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Kevin Ollie strongly encourages his Huskies to challenge each other.
Mangum, Mathews connect on 2 4th-quarter TDs; BYU overcomes 3 turnovers to beat UConn 30-13
' Dead and buried:' Saban scoffs at perceptions whether it's Alabama fading, or is on the rise
Struggling Nebraska off to worst start since 1959, new coach Mike Riley already feels heat
High school roundup: East Lyme girls get three more goals from deLaforcade, remain unbeaten
Glastonbury holds steady at No. 9 in Day Top 10, despite last week's loss
College roundup: Coast Guard's Behne named NEFC Defensive Player of the Week
Mark Behne, a free safety at the Coast Guard Academy, was named New England Football Conference Defensive Player of the Week after registering two fourth-quarter interceptions Saturday in the Bears' 21-14 win at Maine Maritime.
Todd Bennett of Norwich won the Jack O'Keefe Memorial Strides 10K race on Sunday.
CC Sabathia to enter alcohol rehab, miss playoffs; Yankees pitcher vows to 'get myself right'
Keuchel on 3 days' rest, Astros still have something to prove against Yanks in wild-card game
8 p.m., ESPN, WFAN (660-AM), WXLM (980-AM) — AL playoffs: Houston Astros at New York Yankees.
2:30 p.m., CSN — NBA preseason: Boston Celtics vs. Olimpio Milano from Milan, Italy.
8 p.m., ESPN2 — WNBA finals: Indiana Fever at Minnesota Lynx in Game 2.
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The Connecticut Sun announced Thursday that Anne Donovan has decided to resign as the franchise's head coach.
Connecticut Sun center Kelsey Bone set career highs in shooting, scoring and rebounding this past season and was rewarded for her efforts by being chosen as the 2015 WNBA Most Improved Player.


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Five things: You say goodbye
Ryan Lambert
April 11 2012 01:01PM
1. A new wrinkle
Boy am I ever obsessed with the ongoing Jarome Iginla/rebuild drama.
Reached for comment on his situation with the team vis a vis his future, Jarome Iginla said something to the effect of, "I don't know if I want to be around for a rebuild."
The Flames Fifteen: #14 - Chris Breen
Kent Wilson
April 10 2012 05:14PM
If we had done this review a year ago, Chris Breen probably would have placed a lot higher on the list. A free agent signing out of the OHL, the towering 6'7" defender became a favorite of then coach Jim Playfair. The big guy was a top-two defender for the Heat under Playfair and was consistently singled out by the bench boss as a kid who was close to make the jump to the big league.
Sutter/Feaster Press Conference Open Thread
Kent Wilson
April 10 2012 11:03AM
These things tend to be a bit of a dog and pony show (as anyone who heard the Burke presser today can attest) but whether the Flames decision makers decide to be candid or obfuscate, their reponses should be interesting either way.
Follow along with the festivities via the Flames site here. Post your reactions in the comments.
Flames Prospect Playoff Overview
Kent Wilson
April 09 2012 05:37PM
While the big boys aren't going to be skating this spring, the Flames organization nevertheless has a few guys still playing meaningful hockey. Because they are scattered through various leagues, I decided to put together this guide to help find and track the kids as they move along.
Black Box: Week 27
Robert Vollman
April 09 2012 10:14AM
It's small comfort, but the Calgary Flames are the best non-playoff team for the third season in a row, save for being a single point behind Dallas in 2010-11. They had a better regulation record than the San Jose Sharks, but unfortunately random skills competitions are part of today's game and their 5-16 record were one of the many small things that did them in.


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The Earls Mansions D
from £421 /night help Price for guests, Nights
from £421 /night help Price for guests, Nights
Estimated nightly price based on a weekly stay. Excludes fees (if applicable). Enter your dates to see the total cost.
Apartment / 3 bedrooms / sleeps 7 Home 591248
Availability Your dates are available
Apartment / 3 bedrooms / sleeps 7
|Key Info
This fantastic serviced apartment with 3 bedrooms is situated within an elegant property, built at the end of the nineteenth century in Earls Court. Each apartment is individually designed and decorated with a variety of layouts to match your requirements. The location is unrivalled at 5 minutes from Earls Court on the district line, you will be in South Kensington in a matter of minutes and with fantastic transport links to the central London, the joys of Buckingham Palace and shopping in Covent Garden are never far away. The museums of Kensington are a leisurely walk or short tube ride away and the Earl's Court exhibition centre is a mere 7 minutes walk, whilst Westfield White City is close by.
There are four 3 bedroom and 3 bathroom apartments available in this stunning property. Each has a slightly different layout and they all consist of a generous living room, a stylish well-fitted kitchen with a washer and dryer, two bedrooms with double beds or single beds depending on the format you would like. There are also another 2 beds available for this apartment. The property benefits from a maid service 5 days a week. There is parking nearby on a meter or garage and cots can be provided for babies
Facilities & Services
There is central heating throughout the apartments and electric fans for the height of the British summer. There is a CD Player/Radio as well as modern televisions with satellite TV and DVD players upon request. The fully fitted kitchen is equipped with a coffee maker, toaster, 4 hobs, a fridge freezer, microwave, oven and a kitchen welcome pack. Hair dryers can be made available upon request
Earl's Court is the ideal location for a family break or short city break for couples and would be fantastic for professionals on business. Electricity, bed linen, WiFi and towels are all provided.
General Booking Information
All of the apartments within the block are finished to an exceptionally high standard, with only the layout of each apartment differing slightly.
Secure Payments via Sage Pay (Mastercard, Visa, Visa Debit, Visa Delta, Solo, JCB, Maestro) or Bank Transfer
|Sleeps up to 7, 3 bedrooms
|Will consider
|Long term lets (over 1 month)
|Family friendly
|Great for children of all ages
|No pets allowed, No smoking at this property
Features and Facilities
|Internet access, DVD player
|Central heating, TV
|Kettle, Toaster
|Clothes dryer, Dishwasher, Cooker, Microwave, Fridge, Freezer, Washing machine
|3 bedrooms, 3 bathrooms of which 3 Family bathrooms
|Double beds (3), Single beds (1), Dining seats for 8, Lounge seats for 8
|Linen provided, Towels provided, High chair
|Bicycles available
|Not suitable for wheelchair users
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Ahryan Astin scarfs on a huge cock to get the creamy filling
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Lost 5x13: "Some Like It Hoth"
View Single Post
April 16 2009, 03:04 AM
Agent Richard07
Re: Lost 5x13: "Some Like It Hoth"
I gave it an "average". That's not necessarily bad, it just means that it was a decent enough installment, but wasn't anything special.
Anyway, it looks like we got not one, but TWO Star Wars references and
was right about one of them. I thought Miles was gonna tell Chang that he was his son, but it didn't happen. Oh well.
Looks like we got another surprise too. There seems to be a third party at work that isn't Ben or Widmore. I wonder who it could be.
By the way, what did Miles say about the 3.2 million dollars? I didn't catch what was said.
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Here's what you need to make a set to adorn your own garden or to give to your favorite gardener:
- 10" Zinc Garden Markers (I found mine at our local Bachman's garden center)
- 18-gauge wire (or thickness to fit your beads)
- Assorted glass seed beads (size 6/0 "E")
- Decorative Silver-toned beads (Butterfly and Dragonfly found at Michaels)
- Metal Alphabet Stamps (I used 1/4" stamps for the markers in the photo.)
- Hammer, small pliers/wire cutter, pencil, tape, and ruler.
- Acrylic sealer - optional


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Womens Volcom Long Underwear - Base Layer TopsWomens Volcom Base Layers are in stock and ship out blazing fast from The House Boardshop. Womens Volcom Base Layer Gear has all the awesome foul weather protection you need to stay extra toasty and comfortable all winter long. Volcom Base Layers are durable, machine washable and more affordable than ever when you shop with us. We'll ship out your new Snowboard Gear within 24 hours Monday-Friday.
Volcom Long Underwear - Base Layer Tops
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Wickham-LovittPublished 12:02am Sunday, June 30, 2013
Mr. and Mrs. Lonnie Wickham of Natchez announce the engagement of their daughter, Abby Rene Wickham, to Ralph Cameron Lovitt III, son of Mr. and Mrs. Cameron "Bo" Lovitt Jr. of Hattiesburg.
The bride-to-be is a graduate of Adams County Christian School in Natchez and a graduate of the Cardiac and Vascular Institute of Ultrasound in Mobile, Ala.
She is the granddaughter of the late Mr. and Mrs. Sam Tuccio and the late Robert Wickham and Bobbie Wickham, all of Natchez.
The groom-to-be is a graduate of Oak Grove High School in Hattiesburg and a graduate of Belhaven University in Jackson.
He is self-employed as a petroleum land man in Hattiesburg.
He is the grandson of Nelene Steed and the late N.M. Steed and Mr. and Mrs. Ralph C. Lovitt, all of Natchez.
The wedding will be at 6 p.m., Saturday, July 27, 2013, at the Eola Hotel in Natchez.
A reception will follow the ceremony. Family and friends are invited.


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Elizabeth Olsen: 'Winslet inspired me to bare all'
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- Prev
Elizabeth Olsen has credited Kate Winslet with giving her the "courage" to bare all on camera after fearing she would ruin her career by stripping off.
The Hollywood newcomer, who is the younger sister of actress twins Mary-Kate and Ashley Olsen, was terrified about shooting naked scenes for new movie "Martha Marcy May Marlene."
But after seeing Winslet appear completely nude in 1999 movie "Holy Smoke," the 22 year old admits she felt inspired to shed her clothes for the drama, in which she plays a young woman who flees from a cult.
She explains, "(Martha Marcy May Marlene is) only my second film, I got nervous. 'Wait, does this set a precedent for me? Are people going to think I'm just game for that?' Because I'm not. When it's sensationalized or gratuitous, I have no interest in it. But for this movie, it's so a part of the nature theme that's explored and the loss of identity...
"Kate Winslet in that film (Holy Smoke) has much more difficult, physically vulnerable scenes than I did in this movie and it was so impactful. And I was thinking, 'Look at her career now. She's not pigeonholed, it just is the story.' And that was a lesson to learn, to look up to her career as something that's pretty ideal in my mind... That gave me a type of courage of being like, 'I'm going to support the movie, this tells the story better, this is important for the story and that's that.'"
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It was a great hotel. Clean and tidy rooms. There was open bar in the lobby with decorations. Swimming pool was also available. They were very hospitable and friendly. Connectivity with the city was a issue.
I has booked hotel in advance and being confirmed via phone for superior room, and informed to check in late 10-1100pm. I showed up at hotel front there as committed but found no room reserved and all superior room were full. The hotel took no respond and I have had no choice as it was too late then I had...
Three star hotels in Thailand aren't as you get in Singapore and Malaysia. But Jazzotel is a decent 3 star hotel if you don't have a problem with the location. A bit off the city center its a great experience. The hotel buffet is good and the rooms are clean. The elevator closes too fast for people to enter safely....
It was a great stay at this Hotel. The location was good for us. The swimming pool is very clean and worth a dive. The staff is also very friendly.
Check-in was quick. Overall, a memorable stay. Highly recommended
stayed here for a night.. hotel is very old property situated in out skirts of the city...rooms are very spacious but, once again not sophisticated - old furniture and beds.. breakfast spread is ok OK...anyone looking for low budget hotel, this might really fit in...
The beds and bathroom were clean. The breakfast spread in the morning was great. There's a convenient 7-11 across the street. The view wasn't great and the lights in the room are not pleasing. Overall it was a good 2 nights stay for us two 21 yr old girls.
I stayed for 2 nights with my cousin at the start of our Southeast Asia trip. It was close to my uncle's house so it was very convenient for us. A lot of my family members stay there when visiting Bangkok, so they all recommended it. The hotel lobby is nicely decorated and open, surrounded by windows. Our room was...
I was on vacation to Bangkok with my wife. I got a corner room on 16th floor. The view was nice from windows. The hotel was excellent and clean. The breakfast was also very nice. The hotel is little bit in outskirts of bangkok but still it's certaily recommended.
This was our first stop of our long tour of Bangkok, KL & Singapore. Obviously, the expectation was different. We had also asked our operator, SOTC, to get a hotel near to the shopping districts, but keeping with the promise of the worst service possible, they gave us this hotel far away in the outskirts. Our Thai flight landed in...
I have previously stopped in the Swiss Hotel, which is located further away from our Bangkok office so asked to try a hotel nearer. The Jazzotel is a quarter of the cost of the Swiss, it is situated in a quite area so a good night sleep was achieved throughout my stay.
The hotel is dated and starting to need...


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The narrator of Francis's 26th mystery is Tony Beach, a young widower who fights his grief by keeping busy at his wine shop and by socializing. Eventually he teams up with private detective Gerard McGregor to find the hijackers of several trucks of spirits; the pair then take on a case involving the adulteration of whiskey and wine at a cafe. In rapid order the cafe's steward is brutally murdered, and Tony and Gerard just miss being killed. Tony's severest test occurs at the "stunning climax of what may be judged the best of Francis's bestsellers so far; it's a corker," PW commented.
Copyright 1986 Reed Business Information, Inc. --This text refers to an out of print or unavailable edition of this title.
A regular winner ... as smooth, swift and lean as ever Sunday Express As a jockey, Dick Francis was unbeatable when he got into his stride. The same is true of his crime writing Daily Mirror --This text refers to an out of print or unavailable edition of this title.See all Editorial Reviews
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I really enjoy Mr. Francis' books. I'm not a racing enthusiast, but the details about racing are still interesting. Read morePublished 1 month ago by Bonnie Dickson
A great DF book. What he is all about. Nice crisis at the beginning, avoids cliches as much as thrillers can, and excellently written and conceived. Read morePublished 2 months ago by Lars Pendicott
Typical Dick Francis, full of twists and turns, informative and informational. It is a great read and will be educational if one is interested in wine and adult beverages.Published 2 months ago by C. Daniel McClean
Tony Beach, a wine merchant with a talented palate, is enlisted to help investigate a scam involving fine wines and single malt scotches. Read morePublished 3 months ago by Joe Da Rold
I just this author. His books are well researched , gripping and very entertaining. Can't put it down once you start.Published 4 months ago by R. Kruger


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Shambo's gone. What about the rabbits, llamas and elephants?Steve Boggan: There is more bad news for animal lovers: another bull and a water buffalo at the same community have tested positive for the disease.
Comment & features p2
Massive cars and man bags are the essential accessories at Old Trafford
Barney Ronay: When you play for Manchester United, it's not enough to be a massive star at a massive club. You've got to have a massive space to put your massive car too.
Comment & features p3
We are coming for your children
Commercials for junk food are being banned on children's television, but advertisers are moving onto a new battlefield - the internet. Helen Pidd reports.
Comment & features p4
'No one made films like him'
Ingmar Bergman, the Swedish film-maker who died yesterday, transfixed and inspired generations of cinema-goers. Here, some of his greatest admirers explain why he mattered.
Comment & features p10
Sick on arrival
It's no fun being ill on holiday. So why do so many of us succumb every time we finally wind down? Emine Saner finds out how to break the cycle.
Comment & features p16
Five ways to ... avoid spots
Everyone gets the odd spot. Spots occur when there's a build-up of oil called sebum under the skin.
Comment & features p17
Game of three halves
This Sunday's London Triathlon has attracted a record number of competitors, but who'd have thought that swimming 1,500m, then cycling 40km, and finally running 10km would ever become so popular? Robbie Hudson reports.
G2 Comment & features p18
Does it work?
This summer's fitness fashion statement, the FitFlop, is supposedly a thigh-toning sandal that has gathered a cultish following among wearers convinced it gives them longer, leaner legs.
Comment & features p19
The Great Big Glorious Book for Girls by Rosemary Davidson and Sarah Vine
'Remember to remove your mascara before going to bed. Otherwise you might be seen as a slut and a disgrace to your family.'
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This is a warning
Andy Warhol famously flirted with celebrity, but his fascination with modern life contained a much darker edge. It is his obsession with violent death that teaches us the most about the spirit of our age, says Jonathan Jones.
Comment & features p23
Portrait of the artist: Paco Peña, flamenco guitarist
'I moved to London - a year later, I was playing with Jimi Hendrix'
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Draw a skyscraper on your blotter today
Forget the high-rise slums of the past. Building upwards not outwards is the way ahead.
G2 Comment & features p28
The road less travelled
The Roma in films are a byword for adventure and song. How about showing them as human beings, says Louise Doughty.


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A multi-queue, cyclic-service model with a single-message buffer is considered. Each message consists of a number of characters, and one character is served at the server's each visit. Exact and explicit expressions are derived for performance measures, such as mean cycle time, mean message response time, and mean response time conditioned on the message length. The same model was previously solved by approximation by Wu and Chen [IBM J. Res. Develop. 19, No. 5, 486-493 (September 1975)].
Note: The Institute of Electrical and Electronics Engineers, Incorporated is distributing this Article with permission of the International Business Machines Corporation (IBM) who is the exclusive owner. The recipient of this Article may not assign, sublicense, lease, rent or otherwise transfer, reproduce, prepare derivative works, publicly display or perform, or distribute the Article.


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Readership: Scholars and graduate students in classics, art history, English, German, French, and the history of philosophy and ideas.
Brooke Holmes, Assistant Professor of Classics, Princeton University, and W. H. Shearin, Assistant Professor of Classics, University of Miami
Brooke Holmes is Assistant Professor of Classics at Princeton University
W. H. Shearin is Assistant Professor of Classics at the University of Miami
"Dynamic Reading is an exciting experiment in perspective. Eleven essays by a range of distinguished scholars come at the Epicurean inheritance from radically different angles, from an ancient Roman who starved himself to death to Mark Rothko, from a 'whore's doctrine of pleasure' to the philosophy of Giles Deleuze. The volume bears witness to the haunting ambiguity of Epicureanism and to its continuing vitality." - Stephen Greenblatt, author of The Swerve: How the World Became Modern
Introduction, Brooke Holmes and W. H. Shearin
1. Haunting Nepos: Atticus and the Performance of Roman Epicurean Death, W. H. Shearin
2. Epicurus's Mistresses: Pleasure, Authority, and Gender in the Reception of the Kuriai Doxai in the Second Sophistic, Richard Fletcher
3. Reading for Pleasure: Disaster and Digression in the First Renaissance Commentary on Lucretius, Gerard Passannante
4. Discourse ex nihilo: Epicurus and Lucretius in Sixteenth-century England, Adam Rzepka
5. Engendering Modernity: Epicurean Women from Lucretius to Rousseau, Natania Meeker
6. Oscillate and Reflect: La Mettrie, Materialist Physiology, and the Revival of the Epicurean Canonic, James Steintrager
7. Sensual Idealism: The Spirit of Epicurus and the Politics of Finitude in Kant and Hölderlin, Anthony Adler
8. The Sublime, Today?, Glenn Most
9. From Heresy to Nature: Leo Strauss's History of Modern Epicureanism, Benjamin Aldes Wurgaft
10. Epicurean Presences in Foucault's The Hermeneutics of the Subject, Alain Gigandet
11. Deleuze, Lucretius, and the Simulacrum of Naturalism, Brooke Holmes


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Efavirenz / emtricitabine / tenofovir Pregnancy and Breastfeeding Warnings
Efavirenz / emtricitabine / tenofovir is also known as: Atripla
Efavirenz / emtricitabine / tenofovir Pregnancy Warnings
Animal studies have revealed evidence of fetal harm with efavirenz. Efavirenz crosses the placenta in animals and produces fetal blood levels similar to maternal blood levels. Efavirenz may cause fetal harm when used during the first trimester. There are no controlled data in human pregnancy. To monitor maternal-fetal outcomes of pregnant women exposed to antiretroviral therapy, an Antiretroviral Pregnancy Registry (APR) has been established. Healthcare providers are encouraged to prospectively register patients. For additional information: apregistry.com As of July 2014, the APR received prospective reports of about 1000 live births after exposure to efavirenz-containing regimens, over 800 of which were first-trimester exposures. Birth defects were observed in 19 of 825 live births with first-trimester exposure and 3 of 171 live births with second or third trimester exposure. One of these prospective reports with first-trimester exposure was a neural tube defect. Also, a single case of anophthalmia was prospectively reported with first-trimester efavirenz exposure; however, this case included severe oblique facial clefts and amniotic banding, a known association with anophthalmia. There have been 7 retrospective reports of findings consistent with neural tube defects (including meningomyelocele), all in infants of mothers with first-trimester exposure to efavirenz-containing regimens (not including this drug). Two cases (1 prospective, 1 retrospective) with findings consistent with neural tube defects were reported with this drug. Multiple defects (Dandy-Walker syndrome) in a fetus from a spontaneous abortion and neural tube defects in a fetus from a pregnancy terminated during the second trimester have also been reported. Both mothers had first-trimester exposure to efavirenz-containing regimens. Causality could not be clearly established in any of these cases. Pregnancy should be avoided during use of this drug. Barrier contraception should always be used in combination with other methods of contraception (e.g., hormonal). Use of adequate contraception for 12 weeks after drug discontinuation is recommended. Women of childbearing potential should undergo pregnancy testing before starting therapy and should be advised to notify their physician if they become pregnant during therapy. AU TGA pregnancy category D: Drugs which have caused, are suspected to have caused or may be expected to cause, an increased incidence of human fetal malformations or irreversible damage. These drugs may also have adverse pharmacological effects. Accompanying texts should be consulted for further details. US FDA pregnancy category D: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
This drug should not be used during pregnancy unless there are no alternatives and the benefit outweighs the risk to the fetus. AU TGA pregnancy category: D US FDA pregnancy category: D Comments: -Effective contraception is recommended during therapy and for 12 weeks after the last dose; local protocol should be consulted regarding contraception timing. -If this drug is used during the first trimester of pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential harm to the fetus.
Efavirenz / emtricitabine / tenofovir Breastfeeding Warnings
EFAVIRENZ: Milk samples from 13 mothers and plasma samples from their breastfed infants were taken 3 to 4 hours after the last dose. The mothers, who averaged 15.8 weeks (range: 6 to 25 weeks) postpartum, used efavirenz 600 mg daily with lamivudine and (zidovudine [n=12] or stavudine [n=1]). Skimmed breast milk efavirenz levels averaged 3.5 mg/L (range: 1.3 to 7.4 mg/L) and infant plasma levels averaged 0.86 mg/L (range: 0.4 to 1.5 mg/L). Infant plasma levels averaged 13% of maternal plasma levels; correlation not statistically significant. Average plasma levels were slightly below the level effective for HIV suppression in adults. No side effects were reported in the infants after 6 months of breastfeeding, none had developed HIV infection, and all were developing normally. Breast milk from 51 HIV-infected nursing mothers and blood samples from their exclusively breastfed infants were obtained 12 to 14 hours after a dose and dried; the mothers were using efavirenz 600 mg once a day (as part of antiretroviral regimens). Breast milk level averaged 2280 mcg/L (interquartile range: 1180 to 3270 mcg/L) and infant plasma level averaged 178 mcg/L (interquartile range: 88 to 340 mcg/L). The maternal CYP450 2B6 rs3745274 genotype affected breast milk levels and infant plasma levels; the TT genotype had statistically significant higher milk levels than the GG or GT genotypes and the TT and GT genotypes had statistically significant higher infant plasma levels than the GG genotype. An infant dose of 340 mcg/kg/day (median) was estimated. About 146 days after delivery, mid-feed milk samples were collected from 5 mothers at 0.5, 1, 2, 4, 8, 12, and 24 hours after an evening dose; they were using efavirenz 600 mg orally daily (as part of antiretroviral regimen). The peak level averaged 4.5 mg/L at about 4 hours postdose; the trough milk value averaged 2.5 mg/L. Efavirenz was measured in 117 breastfed (90% exclusive) infants whose mothers used efavirenz for HIV infection during pregnancy and postpartum. The drug was detectable in all plasma samples at 0 (mean 1.7 mg/L), 8 (mean 0.3 mg/L), and 12 (mean 0.3 mg/L) weeks postpartum. It was also detectable in all hair samples at 12 weeks postpartum (mean 1.9 ng/mg of hair; range: 0.34 to 11 ng/mg). According to author interpretation, the results suggest infants have substantial exposure to efavirenz during breastfeeding. EMTRICITABINE: Breast milk samples from 5 HIV-1-infected women show emtricitabine is secreted in human milk. Average peak and trough drug levels in breast milk were 679 and 177 mcg/L, respectively. An exclusively breastfed infant would receive about 2% of the proposed emtricitabine dose for infants (estimated). Infants breastfed by mothers treated with emtricitabine may be at risk for developing viral resistance to emtricitabine. Other emtricitabine-associated risks in such infants are unknown. TENOFOVIR: Breast milk samples from 5 HIV-1-infected mothers show tenofovir is secreted in human milk. Average peak and trough drug levels in breast milk were 14.1 and 6.8 mcg/L, respectively. An exclusively breastfed infant would receive about 0.03% of the proposed tenofovir dose for infants (estimated) and attain trivial infant serum levels. The impact of this exposure in infants breastfed by mothers treated with tenofovir is unknown. Breast milk samples were obtained at various times postpartum from mothers who received a single 600 or 900 mg tenofovir dose during labor. Tenofovir was detected (greater than 2.5 mcg/L) in 75% of samples collected from 25 mothers during the first 2 days postpartum; levels ranged from 6.3 to 17.8 mcg/L. At 4 to 6 days postpartum, only 1 of 21 milk samples had detectable drug level (15.7 mcg/L). Serum tenofovir levels were measured in 5 exclusively breastfed infants whose mothers were treated with tenofovir 245 mg daily; infant age averaged 1.8 months. The drug was undetectable (less than 0.005 mg/L) in the serum of 4 infants; serum level was 0.0055 mg/L in 1 infant. No adverse outcomes on standard developmental parameters were observed in two 4-month-old infants whose mothers were treated with tenofovir 245 mg daily; the infants were exclusively breastfed for 3 months.
Breastfeeding is not recommended during use of this drug. If replacement feeding is not an option, the WHO recommends a triple-drug regimen for HIV-infected women who are nursing; the 3 components are included as a first-choice regimen. Excreted into human milk: Yes Comments: -The effects in the nursing infant are unknown. -The US CDC, American Academy of Pediatrics, and manufacturer advise HIV-infected women not to breastfeed to avoid postnatal transmission of HIV to a child who may not yet be infected. -Local guidelines should be consulted if replacement feeding is not an option.
See Also...
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.


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The 2015 UCI World Championships in Richmond, VA Continue reading
The 2015 UCI World Championships in Richmond, VA Continue reading
Friday Night at the Figure 8 Track. Continue reading
Some pix from an embed with team Champion Systems / Stan's No Tubes during The Philadelphia Cycling Classic.
A windy night at Floyd Bennett Field, in Brooklyn.
Roller Races, NYC-Style. Continue reading
An old pro explains how it's done. Continue reading
Pictures from a very wet edition of the Red Hook Crit. Continue reading
Finally a warm- or not-freezing- day in New York. Continue reading
It was below freezing this morning in Central Park, with a real feel of freakin' cold. Continue reading
Being a "third world country", Guyana has minimal traffic rules. Continue reading
We were warned it would be steep, and rough, and there would be no support…. Continue reading
A 10am start had sounded luxurious when I signed up for Whirlybird Cross Continue reading
I dusted off the cross bike, woke up at a ridiculously early hour, and headed up the Palisades Parkway to exit 17. Continue reading


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Thai Chicken with Basil
The essence of Thai cooking, the blending of cool and hot flavors, such as cilantro, basil, ginger, garlic, and chiles, lends an exotic touch to this stir-fry.
Total Time:
Level: Moderate
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- 1 lb. skinless, boneless chicken breast halves
- 3 tbsp. Asian fish sauce (nuoc nam)
- 1 tbsp. soy sauce
- 1 tbsp. brown sugar
- 2 tsp. vegetable oil
- 1 large onion
- 2 red or green chiles (serrano or jalapeño)
- 2 tsp. fresh ginger
- 2 clove garlic
- 1½ c. loosely packed fresh basil leaves
- With knife held in slanting position, almost parallel to cutting surface, cut each chicken breast half crosswise into 1/4-inch-thick slices. In medium bowl, combine fish sauce, soy sauce, and brown sugar; add chicken slices, tossing to coat. Let marinate 5 minutes.
- In nonstick 12-inch skillet, heat oil over medium-high heat until very hot. Add chicken with marinade and cook, stirring frequently (stir-frying), until chicken loses its pink color throughout, 3 to 4 minutes. With slotted spoon, transfer chicken to bowl.
- Add onion to marinade remaining in skillet and cook, stir-frying, until tender-crisp, about 4 minutes. Stir in chiles, ginger, and garlic; cook 1 minute longer.
- Return chicken to skillet; heat through. Stir in basil leaves just before serving.
- To order The All New Good Housekeeping Cookbook, click here.
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Dating back to 1805, this fascinating house was once the home of a celebrated local schoolmaster. Now sympathetically restored to its former glory, this is an excellent location for anyone wishing to ...More about Roscrea
This gracious manor house has 14th-century origins and provides a high standard of accommodation, with elegant bedrooms and bathrooms complete with spa baths. There are extra luxurious touches through...More about Nanscawen Manor House
Set in ten acres, this is a wonderfully peaceful base from which to explore the delights of Cornwall. Originally a farmhouse, dating back to the 17th century, there is something here for all the famil...More about Mount Pleasant Farm
Just a short walk from the town centre, this grand Victorian house offers comfortable accommodation and a genuine homely atmosphere. Many of the bedrooms have the original fireplaces and all are equip...More about Penrose B&B
This 18th-century former posting inn retains many original features and provides comfortable accommodation. Bedrooms are located in both the main house and adjacent coach house - all provide the same ...More about Trehellas House Hotel & Restaurant
Currently the rating for this establishment is not confirmed. This may be due to a change of ownership or because it has only recently joined the AA rating scheme.�� ...More about Port Gaverne
This fine Victorian house was once the vicarage, and the current owners have created appealing and contemporary accommodation for their guests. All bedrooms offer high standards of comfort with elegan...More about Shutta House
Impressive Penarwyn House stands in tranquil surroundings close to main routes, with The Eden Project, The Lost Gardens of Heligan, Fowey, the coastal footpath and National Trust properties all close ...More about Penarwyn House
Whether you're just seeking relaxation or aiming to strike out on Bodmin Moor, you'll find the Premier Inn Hotel Bodmin is in a good location. With great links to the A30 and A38 this hotel could be t...More about Premier Inn Bodmin
This welcoming 15th-century farmhouse is surrounded by countryside and makes a good base for touring Cornwall. Bedrooms have thoughtful finishing touches and there is a comfortable lounge. Breakfast, ...More about Trenake Manor Farm


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Dennis Peterson
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Mary Morrell
George Westfall 67640392
Additional information for this memorial. His spouse was Elizabeth Reeves - Birth 1750 in Randolph, Charlotte, Virginia, United States Death 1797 in Parkersburg, Wood, West Virginia, United States They were married in 1765 at her age 15. They had many more children but I haven't researched it enough to add all of them. These were my 3rd G Grandparents.
Added by
Mary Morrell
on Oct 08, 2015 4:37 PM
Bonnie Shirley Amery
Susan Smith #68502055
Finally I got around to re-photoing Susan's headstone, so that it can be read more easily.
Looks like you were just 1 day off.
Keep contributing.
Bonnie Shirley Amery
Added by
Bonnie Shirley Amery
on Oct 08, 2015 8:03 AM
Beth Martin
Eliza Westfall Figley
Hello Dennis, just wondering what your sources are for the parents of Eliza Westfall Figley. Her findagrave memorial says you provided the relationships, Find A Grave Memorial# 78431168. I have a will from Levi Westfall (Simeon Westfall's brother). It's available on Ancestry. In it, Levi leaves money to "his children" among whom he lists Eliza and later he calls out to give money to "Harriet, Tilly and Eliza Figly" should there be anything left over. Harriet and Tilly are definitely his children (Harriet and Matilda) and it seems odd that he'd include Eliza if she were not his daughter. Everyone else on that will is either his child or grandchild.
Please let me know what you think - I'm striving for accuracy in the Westfall family tree. Please either leave a message or contact me by email. Thanks. :)
Added by
Beth Martin
on Oct 04, 2015 11:28 AM
Sue Steward
John Wesley Brooks Sr.
Regarding John Wesley Brooks Sr. bio. Jane died nine years later at age fifty-four
Do you have any info on Jane's death? She is my great grandmother and I have not been able to find any info on her death.
I'd appreciate any info you could give me.
Thanks, Sue Steward
Added by
Sue Steward
on Sep 05, 2015 9:37 AM
Linda Sanders
Noah Westfall 1821-1892
Your post says that the body was either lost or destroyed. He is buried in Falling Water Cemetary in Belgrove, WV. He is my great great grandfather.
Added by
Linda Sanders
on Sep 05, 2015 7:54 AM
Mrs Parrott
RE: Jacob Westfall
I will check my tree and get back to you in a short while.
Thank you,
Added by
Mrs Parrott
on Aug 25, 2015 4:53 AM
Bonnie Shirley Amery
RE: Susan Smith memorial #68502055
You are kind about the quality of that photo, but I did hate to delete it.
I have written myself a note to go back and re-photograph Susan's headstone. I will read the headstone then.
The photograph came from just walking though Smith Cemetery after visiting Mama and Daddy's final resting place and I just snapped photos here and there.
Smith Cemetery is one of my favorite hills to visit.
Added by
Bonnie Shirley Amery
on Aug 20, 2015 8:22 PM
Linda Y
RE: Vincennes city
Think your suggestion is correct. I am adding photos. Funny thing. They have plot locations. But wrong cemetery. Just makes it difficult if someone is trying to add family. Thanks. Just needed a sanity check
Added by
Linda Y
on Aug 17, 2015 9:49 PM
janet donner
RE: Benjamin Hockaday - obit
I think I found some more and hope you got them
I got newspapers.com and its so addicting that I
can find obits I didnt use to be able.
Added by
janet donner
on Jul 12, 2015 5:00 PM
Amos Perry Westfall
Are you still looking for Amos' parents?
Added by
on Jul 01, 2015 3:26 PM
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Antique Rivet Jed Jeans in TelfordSKU: #8303716
Product Information
- There's a mysterious edge about you that only a great pair of jeans can satisfy. Good thing Antique Rivet® knows you so well.
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text:
Massa confident of Ferrari reliability
|By Jonathan Noble
|Tuesday, March 18th 2008, 11:50 GMT
Felipe Massa is confident that Ferrari have nothing to fear about the high temperatures that will greet them in Sepang this weekend, despite the double engine failure in Australia.
The Brazilian and teammate Kimi Raikkonen endured a troubled weekend in Melbourne, and both retired from the race with engine failures - which some suggested could have been caused by the higher than usual temperatures.
But Massa is optimistic that there will be no repeat of the dramas this weekend, and that Ferrari can kick-start their campaign in Malaysia.
"We will put new engines in the car and for sure we can go to the end of two races now," he said. "It wasn't the temperature that affected our engines, it was something else which we need to discover very quickly.
"We need to start a new championship from Malaysia. The championship is long, we know points are very important but we know also that many things can happen in every race."
Ferrari were set to fly the Australian power units back to their Maranello base for a series of evaluations to work out exactly what went wrong, in a bid to find solutions for Malaysia.


text:
All posts tagged "Emily DiDonato"
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Pronovias Dreamy Wedding Dresses–Top model Emily DiDonato has been named as the new face of bridal label Pronovias' Atelier and mainline...2014September 2, 2014
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Emily in Gems–Spanish jewelry label Suarez taps Emily DiDonato for its fall-winter 2014 ad campaign. The dark-haired stunner poses for Mario...2014August 13, 2014
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Emily's Summer Fun–Top model Emily DiDonato shows how to have fun at the beach for the July 4th issue of Elle...2014July 7, 2014
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Let it Snow–Gracing the pages of Vogue Australia's June issue, Emily DiDonato makes one sexy ski bunny in the magazine's cover...2014May 15, 2014
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Emily's Winter Cover–Being on a different hemisphere means that the June cover of Vogue Australia is all about winter. Model Emily...2014May 14, 2014
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Emily in Tulum–American babe Emily DiDonato looks amazing in the summer issue of H&M Magazine–shot on location in Tulum, Mexico. The...2014May 12, 2014
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This week on Instagram…Gisele Bundchen encounters a turtle. Emily DiDonato shoots for Maybelline. Jacquelyn Jablonski's birthday featured a piñata. Ajak Deng...2014April 11, 2014
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Lady or Vamp–A new magazine for women from the makers of Hercules, Vamp, takes a look at the femme fatale and...2014March 15, 2014
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Girls in de la Renta–For his spring-summer 2014 campaign, Oscar de la Renta enlists Emily di Donato and Kate Bogucharskaia for...2014February 9, 2014
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The New Glam–Following up her cover, Emily DiDonato stars in the main editorial for Vogue Turkey's January issue. The American beauty...2014January 23, 2014


text:
Time Change Tonight!!
Ash + John = 3 years of wedded bliss and 1 rough-n-tumble princess!
Faye Rose 1/23/12 - Golden Boobies!! ( . )( . )
Comments (9)
Married to Ryan 06.14.08
Maxwell Jacob 8.25.09
Cole Everett 1.11.12
I'm just happy I get an extra hour of sleep since I have to work at 6am.
Isabella Faye December 24, 2009
Noah Luis January 24,2012
Rockabilly mama to Gigi (Jan 12) and Davey (Dec 13)
EBFing-CoSleeping-NonVaxing-Circing-BWing Semi Crunchy Mama
Don't forget to change your smoke detector batteries as well!
Proud Firefighters wife 5-8-10!
MPG born 1/12/12 @ 1516hrs 7lbs 7ozs and 20.75 inches!
I'm flying back one time zone tomorrow, from Alaska to California, so this is a double bummer. Although, my LO never sleeps or wakes at normal times anyways.
BFing, BWing, CDing, Air Force mommy to Elizabeth (18 January 2012) and Coraline (31 January 2014)


text:
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