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Russell Group results from our site and 24 leading UK universities.
The University of Warwick is one of the UK's leading universities: globally connected, forward-looking and entrepreneurial. It prides itself on its close work with business and the economic and social impact that follows from its academic excellence.
Despite its relative youth – it was founded in 1965 – Warwick has an acknowledged reputation for world-class research at home and abroad. In the most recent UK-wide assessment of the quality of research in universities 37% of the university's research was rated as world-leading and a further 50% rated internationally excellent.
It has an annual turnover of more than £480 million and 38% of its academics and 34% of its students are from overseas. The university's Department of Mathematics hosts one of the UK's few Fields Medallists, Professor Martin Hairer, an Austrian by birth.
More than 14,700 undergraduates, 10,500 postgraduates and 5,500 staff benefit from studying and working in Warwick's innovative, research-rich environment. The university also has a huge impact on the West Midlands region where it is based. Just one example is the WMG (Warwick Manufacturing Group), which has helped to reinvigorate manufacturing industries in the region, brought in significant overseas investment and improved the competitiveness of hundreds of businesses. It won the Queen's Anniversary Prize in 2009.
Visit our website


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bank of queensland ltd
(BOQ:Australian Stock Exchange Ltd)
Last A$12.76 AUD
Change Today +0.04 / 0.31%
Volume 2.0M
As of 1:10 AM 10/13/15 All times are local (Market data is delayed by at least 15 minutes).
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Chief Executive Officer and Director
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United States
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Population: No data availableSeems like we could not load the Census Data for Clay, MI (What should have appeared here). Sometimes this happens when we can not properly match a city or hamlet with 2010 census data. Please go back and click on another area. The error has been logged and we will look into the issue.
Business Industries in Clay
Below is a list of the types of businesses in the City of Clay for which we have Yellow Pages business listings. If you do not see your industry within the list below, adding your business will automatically create it.
Brief Information About Clay
The township of Clay is located in the county of St. Clair. It covers a total area of 214.0 sq. km. The economy of the city is contributed by development of businesses related to auto body work, auto dealership of used and new cars, supplies of boat equipments, supplies of building materials, manufacturing of computer peripherals, freight forwarding, contracting in heating and ventilating, industrial and commercial machinery, supplies of marine equipments, dealership of mobile homes, contracting in remodeling and refinishing and contracting in sheet metal work contributing to the local economy in a positive way.
Recent News from the Green Blog
Each year as a tradition to myself and this green movement website, I write on the events of Earth Day (April 22nd) this year is no exception. I will focus more on some new ideas and representations of our planet Earth. The symbols of Earth Day have been similar throughout the years, including an image or drawing of the Earth..


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Press Room
Association News
Aug 11, 2014
Be sure to take a few minutes to provide feedback to InfoSight.
Aug 11, 2014
The Consumer Financial Protection Bureau said that it has studied the effect of a 2010 "opt-in"...
Aug 11, 2014
Distributed denial of service (DDoS) attacks are becoming more common against credit unions and...
Aug 11, 2014
An employee might not hesitate to respond if their superior asks for secure information, and that's...
Aug 5, 2014
Credit unions have reached and surpassed 100 million memberships nationwide--equating to one in...
Aug 4, 2014
The FFIEC has posted the new 2014 HMDA and CRA Data Entry Software Release versions for 2014.
Aug 4, 2014
The National Credit Union Administration has released the first videos in a new series on fraud...
Aug 4, 2014
PowerComment, a new online resource that helps credit unions take their regulatory concerns...
Aug 4, 2014
The civil money penalty process and how it applies to late call-report filers are detailed in the...
Jul 28, 2014
Be sure to complete the InfoSight Users' Survey.
CU News
Oct 2, 2015
Steve Arbaugh, CFO and SVP of Finance at SECU has been elected to the governing board of trustees...
Oct 1, 2015
Credit Union Foundation MD|DC proudly presents Motown, The Musical, on March 13.
Oct 1, 2015
Sharonne Bonardi, a member of the Board of Directors of SECU, has been named Deputy Comptroller by...
Sep 30, 2015
Andrews FCU attends Volvo VIP evening at Egmont Palace in Brussels, Belgium.
Sep 30, 2015
Andrews FCU is serving as the Prime Sponsor for the 2015 New Jersey Run for the Fallen, donating $5...
Sep 30, 2015
DE program has 46 new graduates, including one from MECU of Baltimore, Inc.
Sep 30, 2015
Through partnerships between Educational Systems FCU and local minor-league baseball teams, more...
Sep 30, 2015
Educational Systems FCU Supports Professional Development at the Learning Forward Maryland Annual Dinner
The Learning Forward Maryland Annual Dinner Meeting and Awards Program was recently held at the...
Sep 30, 2015
Miriam Rivera Lieb Vellek former CEO of Transportation Federal Credit Union died peacefully at home...
Sep 29, 2015
The 2015 Women's Leadership Conference received high ratings.
RSS News
Mar 23, 2015
A report from the Federal Housing Finance Agency released last week highlights the activities the...
Mar 23, 2015
New solution aims to help in-house teams manage their electronically stored information.
Mar 23, 2015
Four credit unions are out more than $850,000.
Mar 22, 2015
The Temporary Corporate Credit Union Stabilization Fund receives sixth consecutive clean audit...
Mar 22, 2015
Founder Mike Welch offers advice to national groups in his first CU Times column.
Mar 22, 2015
Credit union industry professionals and executives to partner with small asset, minority owned and...
Mar 22, 2015
Credit unions need to stand out by digging into their mission.
Mar 22, 2015
This year, CU Times honored five executives, one volunteer and two credit unions for their...
Mar 22, 2015
How much have the credit union challenges changed in 25 years?
Mar 20, 2015
Max Credit Union investigates whether an employee made negative comments about a member online.
No news found.


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National Vampire Awareness Day - Take Two!
Peter Hanlon | Posted 05.25.2011 | Green
Read More: Holiday, Standby, Power Strip, Electricity, Vampire Awareness Day, Household Energy Use, Electric Grid, Vampire, Conservation, Phantom, Load, Green News
Originally published at Ecocentric. So here's a mystery to consider: Why didn't National Vampire Awareness Day catch on? Much of the world is still ...


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Blog owned and operated by an ex Trimet bus driver-Most of my social media time is spent on twitter https://twitter.com/AlYourPalster
Thursday, December 22, 2011
Ridership drops?
According to the latest chart it does
But the press release shows bus riders and max riders up?
Oh yea, they use statistics from A YEAR AGO!
Watch out!
The signal timing at Hillsboro Transit Center (HTC) has raised concerns about potential conflicts between TriMet buses exiting the HTC and westbound MAX trains approaching the platform.
Subscribe to: Posts (Atom)


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Motorists trying to turn in to the East F Street McDonald's in Oakdale to get their French fry or Big Mac fix will have to wait a while to place that order.
A year from now, if all goes as planned, some 3,250 acres within the Oakdale Irrigation District will use water much more efficiently.
Entries are now being accepted for the second annual Central California Arts Showcase exhibition taking place this spring at the Carnegie Arts Center in Turlock and the Mistlin Gallery in Modesto. The juried exhibition is a unique collaboration between the region's two premier visual arts galleries celebrating regional artistic excellence. For this show both galleries will be exhibiting works selected by a single panel of judges. Entries of works in all media are being accepted now through February 27, 2015, and the show will be on display at both galleries from April 1 through May 8, 2015.
U.S. Representative Jeff Denham (R-Turlock) introduced a bill on Wednesday, Jan. 14 to lessen the burden on disabled veterans by extending military commissary and exchange store privileges to former service members and their families.
Oakdale Chamber of Commerce will host its 69th Annual Awards on Friday, Jan. 16, 2015 from 6 p.m. to 9 p.m., staged at the Gene Bianchi Community Center, 110 S. Second Ave., Oakdale.
The Bacigalupi family is well known throughout the Oakdale area. Not only for the infamous H-B Saloon on F Street, but also for their philanthropy including sponsoring the Cowboy Golf Tournament, the annual AFC-NFC Championship Tailgate Party to benefit local causes, donations to Spirit of Oakdale, Community Sharing, the Lions Club Children's Christmas Shopping Tour and several contributions to Oakdale High School sports.
Crab season is alive and well and Oakdale Junior High School's Parent Teacher Club is ready to get cracking.
The Associated Students of Modesto Junior College (ASMJC) is teaming up with Students United Reaching for Equality (SURE) and MJC's International Student Program to host a workshop for high school seniors and recent graduates on how to make college a reality, with an emphasis on assisting California Dream Act students and those who need information about financial aid. The California Dream Act allows undocumented and nonresident documented students who meet certain provisions to apply for and receive community college fee waivers, Cal Grants, state-administered financial aid, university grants, and private scholarships funded through public universities.
Life is not being wasted on Bill and Joanne Parker. At the ages of 85 (Bill) and 84 (Joanne), this couple did not wait for New Year's Day to make a resolution or begin a new health plan. On Jan. 2, 2015 the couple could be found in the same place they were on Dec. 31, 2014 … putting in some time at Fitness Plus in Oakdale.
The adage 'one man's trash is another man's treasure' was well portrayed in a recent Stanislaus River homeless camp clean up on Wednesday, Dec 31.
Like many families do, the 'family' of kids, parents and teachers at The Learning Tree Preschool in Oakdale recently completed their holiday 'Gingerbread House' craft making activity, with the children able to take home their sweet treats to display (or eat) over the holidays. Following are some photos from the special craft day.
Law enforcement fatalities in the U.S. rose 24 percent in 2014, reversing what had been two years of dramatic declines in line of duty deaths, based on preliminary data compiled and released by the National Law Enforcement Officers Memorial Fund (NLEOMF).
Assembly Republican Leader Kristin Olsen, (R-Modesto), issued a statement following Governor Jerry Brown's inaugural address on Monday, Jan. 5:
Major construction activities associated with the State Route 99/State Route 219 Kiernan Avenue Interchange Reconstruction Project are now under way.
Thanks to the generosity of Raley's customers, employees and community partners, Raley's Food For Families annual holiday bag campaign surpassed its goal by nearly 50 percent, raising 2.9 million pounds of food in Northern California and Northern Nevada. The total, raised from Nov. 7 through Dec. 31, is among the highest in recent years and set a new bar for 2015.
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The date is getting closer and time is running out to buy advance tickets for the Seventh Annual "Taste of Oakdale" sponsored by the Oakdale ...
Lance Campbell will be busy with more than class prep for his Social Studies students at East Stanislaus High School in the 2015-16 school year ...
The Oakdale Children's Play Park, in Dorada Park on the corner of East A Street and North Second Avenue, was a vison of Dorene ...
After the Oakdale City Council authorized replacement of $37,000 worth of outdated critical fire equipment on Monday, Aug. 17, the council also agreed to ...
After the July removal of Hughson Mayor Matt Beekman from the Local Agency Formation Commission (LAFCO), Stanislaus County mayors on Wednesday, Aug. 12 appointed Oakdale ...
The 2015-16 school year is off to a promising start for Oakdale High School senior Michael Winders.
A group of new home buyers in the JKB Homes Belmont division of Bridle Ridge are perplexed and in the dark when it comes to ...
Oakdale Police were investigating the case of a dead body found in the water at the Stanislaus River under the Yosemite Avenue Bridge on Thursday ...
Oakdale Joint Unified School District board members reconvened after a one month break for summer on Monday, Aug.10 at Oakdale City Council Chambers.
Page 5 of 5
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Keep The Moose in Your Facebook Feed
So you're a Moose fan, but Facebook won't let you stay up to the minute on all that's happening? We feel your pain, but now there's a way to make sure the Moose is your top priority.
So you're a Moose fan, but Facebook won't let you stay up to the minute on all that's happening? We feel your pain, but now there's a way to make sure the Moose is your top priority.
Facebook can be a positive, powerful tool. An innocent 5-yr-old girl in Salt Lake City is fighting for her life because Type 1 Diabetes was left undiagnosed for too long. Her family created a Facebook page to share her journey and educate others. A simple blood sample could have avoided all the agony this family is going through. I had to share this story as it hits close to home. My wife, fortunately, did not face such dangerous consequences when she was diagnosed at the age of 19, but had a scare after not being diagnosed immediately.
Starting today, AMBER Alerts may start popping up in your Facebook news feed.
Facebook announced today a partnership with the National Center for Missing and Exploited Children that will send AMBER Alerts to people's Facebook news feeds in targeted search areas to help find a missing child after an alert has been issued...
We were supposed to be checked out, looking at wildlife and geysers, snapping photos and hiking around, but apparently what we were really doing was checking in on Facebook...
Thanksgiving is less than a week away and now you can celebrate the special relationships for which you're the most thankful with a cool new video feature from Facebook.
For most of my adult life there were only three TV channels and maybe half a dozen radio stations. There was no so called "talk radio."
Yesterday I was sitting at my desk at work checking out the latest "bozeman" related YouTube videos for anything interesting to like and share. What do I find?
Your Facebook feed was probably hijacked this week by all those Facebook 'Look Back' movies your friends posted, capturing the highlights of their time on the social networking site in honor of its 10th birthday.
UPDATE: The issue appears to be resolved.
Are you unable to post to your Facebook timeline or pages? We are having the same issues along with users around the world.
Yeah, I got the riddle wrong. Did the giraffe profile pic thing. If you're one of the dozen people on planet earth who don't know what the Facebook giraffe thing is, here goes...
It's just another way to keep up with The MOOSE, and the happenings around Bozeman so make sure we're Facebook friends, OK? We'd hate for something really fantastic to happen and you not find out about it IMMEDIATELY, you know?
Are you ready for the latest Facebook scandal? Apparently, your Facebook friends could affect your credit! They won't affect your traditional FICO score, but there are a handful of new companies that are analyzing your Facebook friends to determine whether you're a safe bet for credit. If you have friends who are delinquent or default on loans, it reflects badly for you.


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McGinnis: Mom was right about the clean underwear
A man in his birthday suit arrives at the pearly gates, stepping up to St. Peter's window for admission or possible referral to somewhere much warmer and less well lit.
"Well son, I couldn't help but notice you're naked," said Peter The Rock, pushing his ID card camera away for the moment. "Just curious about what brings you here today."
"Wellsir, I have only a sketchy recollection of the events leading up to my death," said the man, attempting to position himself in a less revealing way. "I am dead, right, somebody isn't just pulling one of those 'Jackass' stunts on me?"
"Yessir, you are no longer living. Our job here today is to determine where you will be permanently relocated," said the patron saint of bakers, bridge builders and of course, fishermen.
Without any memory of the man's fatal incident as reference, St. Peter booted up his celestial computer and began searching YouTube, Facebook and Twitter to see if anyone had posted anything that might be helpful.
"You'd be surprised how often that happens," he murmered. "Most of it ends up on Tosh.O."
Next the apostle pulled up security camera video in a 20-mile radius of the fellow's endpoint. Although he did find a snippet of the man buying three fried burritos, a box of Little Debbie oatmeal pies, the family size Flamin' Hot Cheetos and a six pack of Schlitz tall boys at the Quickie Mart on the day of, nothing else turned up.
"Unlike the FBI I don't have the ability to check private email but I'll put in a call to some people there who owe me a favor," said St. Peter. "In the meantime I guess we're gonna have to find you some temporary housing. Let's look at your credit history."
The naked man had wondered what was in the passport pouch hung around his neck with a lanyard. He handed over the paperwork.
"Lessee here. Multiple DWIs, two jail stints for assault, child support issues. Haven't been to see your mother in the nursing home since she went there. We won't even get into the last time you set foot in a church," said St. Pete, raising an eyebrow.
"I don't mean to be discouraging, but this doesn't put you in the best position. Looks like you easily qualify for the Fifth Level, a little development over some swamp land where you'll have lots of neighbors. I hesitate to put you in the Seventh Circle because we haven't determined yet whether or not you have any redeemable qualities."
At this point St. Peter has noticed the "Big Bad Bum" tattoo on the man's left biceps.
"But I was baptized as a boy. We went down to the river and everything," the man said, looking at the River Styx brochure and beginning to realize how serious the situation was becoming.
"I would say you've overlooked the 'sin no more' clause in that contract plus violations of Rule 3 — the part where you're not supposed to reference our Lord and Savior only in profanity."
By now a fishing boat had pulled up on the nearby creek. A meth freak skinny guy in a black hoodie put the trolling motor in neutral and beckoned the naked man with a bony finger.
"Look at it this way," said The Rock, handing the naked man a complimentary bath robe. "At least now you'll have some time to think about the consequences of your actions."
Judith McGinnis, whose column appears here on Thursdays, may be reached at firstname.lastname@example.com or 940-763-7534.
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Posted| Updated
Retail sales have surprised analysts by falling in November, with hardware, furniture and footwear leading the decline.
Topics: business-economics-and-finance, economic-trends, retail, hospitality, australia
A north coast MP says the State Government's tourism strategies could make it tougher for locals to find work in the region.
Topics: hospitality, tourism, byron-bay-2481, lismore-2480
Posted| Updated
Restaurant and Catering SA expected 70 per cent of the state's restaurants to close at times when new penalty rates applied.
Topics: hospitality, retail, industry, business-economics-and-finance, work, community-and-society, states-and-territories, government-and-politics, adelaide-5000, sa, mount-gambier-5290, port-augusta-5700, port-lincoln-5606, renmark-5341, port-pirie-5540
A Canberra coroner finds tigher rules for staff and subcontractors are needed in the wake of the Diamant Hotel fire in Acton last year.
Topics: courts-and-trials, fires, hospitality, act, canberra-2600
New penalty rate arrangements for Christmas Eve and New Year's Eve in SA will go ahead as legislated.
Topics: retail, hospitality, industry, business-economics-and-finance, states-and-territories, government-and-politics, activism-and-lobbying, unions, sa, adelaide-5000, australia
New signs will be placed outside Bulli Hospital over the next few days reflecting the emergency department's transition to an 'emergency primary health care centre'.
Topics: hospitality, doctors-and-medical-professionals, emergency-incidents, bulli-2516
Posted| Updated
Business SA and unions are confident differences over part-day public holidays and penalty rates will be resolved before Christmas.
Topics: retail, hospitality, industry, business-economics-and-finance, states-and-territories, unions, adelaide-5000, sa, australia
Posted| Updated
Fair Work Australia will hold a hearing on costs from new part-day public holidays, but a union official has accused some employers of making a 'song and dance'.
Topics: states-and-territories, unions, government-and-politics, small-business, retail, hospitality, industry, business-economics-and-finance, sa, adelaide-5000, australia
Posted| Updated
There are calls for bottle shop prices to be increased after a study found young people are fuelling up on alcohol before heading out so they can save money.
A tenth of people surveyed in the Deakin University study said they drank more than 11 standard drinks before reaching a venue, and some said they had as many as 25.
The study found that people who drank more than six drinks before leaving home had double the chance of being involved in a violent incident once they were out.
Topics: alcohol, drug-use, health, regulation, business-economics-and-finance, hospitality, industry, retail, geelong-3220, nsw, vic, nt, australia
Posted| Updated
Adelaide City Council has asked the South Australian Government to make some changes to its proposed late night code for venues.
Topics: local-government, hospitality, government-and-politics, states-and-territories, crime-prevention, law-crime-and-justice, adelaide-5000, sa
Civil libertarians have slammed changes to laws in Queensland which would allow hotel and motel owners to deny accommodation to sex industry workers.
Topics: prostitution, hospitality, mining-industry, discrimination, moranbah-4744
Posted| Updated
Echo Entertainment boss John O'Neill tells his shareholders he is not worried about the threat of James Packer's Crown building a second Sydney casino, but not everyone's quite so confident.
Topics: company-news, business-economics-and-finance, hospitality, gambling, australia
Posted| Updated
Andrew Robertson joins us from an event in Sydney where James Packer was speaking.
Topics: company-news, business-economics-and-finance, hospitality, gambling, australia
Posted| Updated
A planned code of conduct would include a 3:00am lockout at SA licensed venues to help curb alcohol-related violence.
Topics: states-and-territories, government-and-politics, hospitality, industry, alcohol, crime-prevention, law-crime-and-justice, laws, adelaide-5000, sa, australia
Posted| Updated
A key private index of services sector activity has found the recent slump in commodity prices is feeding through to companies supporting the miners.
Topics: economic-trends, business-economics-and-finance, retail, money-and-monetary-policy, hospitality, australia
Posted| Updated
A group of South Korean students are set to help ease a hospitality staff shortage in Australia's Northern Territory.
Topics: hospitality, education-collaborative-projects, korea-republic-of, asia, australia
Posted| Updated
Two grand finals on one weekend will offer a bonanza for many businesses, from pubs and gaming to hotels and advertising.
Topics: business-economics-and-finance, food-and-beverage, hospitality, retail, advertising-and-marketing, media, australia, nsw, vic
Posted| Updated
Casino operator Echo has announced that its chief executive Larry Mullin will be leaving the company early next year.
Topics: business-economics-and-finance, company-news, hospitality, gambling, australia, nsw
Posted| Updated
The Fair Work Ombudsman has launched a campaign targeting employers in the hospitality industry.
Topics: regulation, public-sector, hospitality, australia
Posted| Updated
Hotel giant Starwood is opening its biggest hotel yet as it seeks to cash in on Macau's high rollers. Ticky is joined from the island to talk about the business climate up there by chairman and chief executive, Frits van Paaschen.
Topics: industry, business-economics-and-finance, hospitality, macao, australia, asia, china
Posted| Updated
As SA again looks at licensing laws, the Police Commissioner urges 3:00am closing and no more happy hours.
Topics: crime-prevention, crime, law-crime-and-justice, alcohol, drug-use, health, states-and-territories, government-and-politics, hospitality, adelaide-5000, sa
Posted| Updated
Codes of practice will be tightened for licensed venues in South Australia in a bid to reduce alcohol-fuelled violence.
Topics: crime-prevention, assault, crime, law-crime-and-justice, alcohol, drug-use, health, states-and-territories, government-and-politics, death, community-and-society, hospitality, sa, adelaide-5000, australia
Posted| Updated
An Indian takeaway restaurant in Sydney has been fined almost $100,000 after health inspectors found cockroaches and dead rats in the kitchen.
Topics: hospitality, crime, courts-and-trials, animals, kings-cross-2011, nsw
Posted| Updated
Flight Centre's net profit after tax has soared 43 per cent, with all its international businesses profitable before interest and tax.
Topics: business-economics-and-finance, company-news, air-transport, hospitality, retail, australia
Unions vow to fight a proposal by Senator Nick Xenophon to scrap penalty rates for some hospitality and retail workers.
Topics: work, community-and-society, federal-parliament, unions, government-and-politics, activism-and-lobbying, retail, hospitality, industry, business-economics-and-finance, sa, adelaide-5000


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Before man conquered his fear of water, he amused himself with dust sports such as pushing boulders off cliffs, wrestling tumbleweeds, and falling in the dust. Celebrate man's triumph over hydrophobia with this Groupon.
Choose from Three Options
- $5 for general admission for two (up to a $12 value)
- $10 for general admission for four (up to a $24 value)
- $15 for general admission for six (up to a $36 value)<p>
Children 3 and younger are admitted for free and must wear a swim diaper and plastic pants beneath their swimwear.
North Shore Aquatic Center
Open Memorial Day through Labor Day, North Shore Aquatic Center features a pool, waterslides, swim lessons, and other water-related diversions to stoke family-friendly fun all summer long. In the center of a shallow pool, a brightly colored jungle gym invites young hydrophiles to unleash their inner amphibians on its slides and spraying fountains. Elsewhere, a sinuous powder-blue standalone slide whisks giggling riders along its curves and bends before jettisoning them out into the pool, while both high and low diving boards test courage and cannonball splash trajectories. North Shore also holds lifeguard classes, a variety of water exercise and fitness programs which impart the basics of paddling and mermaid sign language.
98% of 1,673 customers recommend
"Great place Kids love it"
"Great fun for the family on a hot day! My 2 year old loves all the slides"
"Very fun pool!!! Great variety"
North Ogden, UT 84414
+18017829712Get Directions


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Shaggy-haired Jacques Burger became renowned for his fearlessness. His willingness to put his body on the line earned him a misshapen nose and legions of fans wherever…
NamibiaAll you need to know about your favourite teams and players
Georgia edge Namibia
Georgia skipper Mamuka Gorgodze guided his jittery team to an error-ridden 17-16 victory over Namibia today which all but guaranteed their place at the 2019 Rugby World…
World Cup live: Georgia v Namibia
Live updates and stats from the Rugby World Cup pool C clash between Georgia and Namibia.
Rugby: Physical Tonga pick up first win
Tonga will feel satisfied they played about as much rugby as could be expected in their 35-21 win over Namibia this morning.
McCaw, Carter selfie targets for Namibians
Richie McCaw and Dan Carter were sought out by the Namibia players for selfies in the All Blacks changing room after the…
All Blacks: Waisake Naholo ready to playVideo
ABs v Namibia: How the media reacted
The All Blacks' emerged from their clash against Namibia with a win but without too much praise from the world's media.
The lost half: Only 12 minutes of action
A dire second spell in the All Blacks' World Cup win over Namibia saw the ball in play for a paltry 12 minutes.
Player ratings: SBW cracks it again
Chris Rattue rates the All Blacks in their 58-14 Rugby World Cup victory over Namibia.
Hansen frustrated at stoppages
All Blacks coach Steve Hansen has expressed his frustration at the constant second-half stoppages which halted his side's…
No injuries the real prize
No records for the All Blacks in their victory over Namibia this morning, but most importantly, no major injuries.


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Page 1
Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with
distinct physiological functions
B Yang1 and S Kumar2
1Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
2Centre for Cancer Biology, SA Pathology and Hanson Institute, Adelaide, SA 5000, Australia
The Nedd4 (neural precursor cell-expressed developmentally downregulated gene 4) family of
ubiquitin ligases (E3s) is characterized by a distinct modular domain architecture, with each member
consisting of a C2 domain, 2–4 WW domains, and a HECT-type ligase domain. Of the nine
mammalian members of this family, Nedd4 and its close relative, Nedd4-2, represent the ancestral
ligases with strong similarity to the yeast, Rsp5. In Saccharomyces cerevisiae Rsp5 has a key role
in regulating the trafficking, sorting, and degradation of a large number of proteins in multiple cellular
compartments. However, in mammals the Nedd4 family members, including Nedd4 and Nedd4-2,
appear to have distinct functions, thereby suggesting that these E3s target specific proteins for
ubiquitylation. In this article we focus on the biology and emerging functions of Nedd4 and Nedd4-2,
and review recent in vivo studies on these E3s.
ubiquitylation; endocytosis; trafficking; receptor; signaling
Ubiquitylation controls biological signaling in many different ways.1,2 For example, the
ubiquitylation of a misfolded or damaged protein leads to its degradation by the 26S proteasome
before it can get to its subcellular site where it normally functions. A ligand-activated receptor
may undergo ubiquitylation, where the tagging with ubiquitin acts as a signal for the
endocytosis of the receptor; thus, removal from the membrane resulting in the termination of
the signal generated by the activated receptor. Ubiquitylation of a cell-cycle inhibitor could
lead to its rapid degradation, allowing cells to progress through the cycle. Thus, protein
ubiquitylation can control signaling by regulating the cellular levels of a protein, by controlling
its subcellular localization, by preventing accumulation of defective or damaged proteins, and
in some instances, by preventing protein degradation. Clearly, a process that is so critical for
cellular homeostasis, is itself tightly regulated by multiple enzymatic steps and many accessory
proteins that provide specificity to the system.
The ubiquitylation of a protein needs conjugation between the carboxyl group of the C-terminal
Gly residue of ubiquitin, and the ε-amino group of an internal Lys (K) in the substrate.1,2 The
© 2009 Macmillan Publishers Limited All rights reserved
Corresponding authors: B Yang, Obstetrics and Gynecology, University of Iowa, 200 Hawkins Dr, 46 MRF, Iowa City, Iowa 52242,
USA. firstname.lastname@example.com; or S Kumar, CCB, SA Pathology, PO Box 14, Rundle Mall, Adelaide SA5000, Australia.
NIH Public Access
Author Manuscript
Cell Death Differ. Author manuscript; available in PMC 2011 January 1.
Published in final edited form as:
Cell Death Differ. 2010 January ; 17(1): 68. doi:10.1038/cdd.2009.84.
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transfer of the activated ubiquitin to substrates occurs through a series of enzymes. These
enzymes include a ubiquitin activating enzyme (E1), multiple ubiquitin conjugating enzymes
(E2), and several hundreds of ubiquitin-protein ligase (E3). A protein can be
monoubiquitylated, multi-monoubiquitylated, or polyubiquitylated, and the type of
ubiquitylation determines the fate of the protein.1,2 Ubiquitin itself contains seven lysine
residues, all of which can participate in the formation of ubiquitin chains. However, in
mammals, K48 and K63 linked chains are most common.1,2 Substrates containing K48 linked
ubiquitin chains are usually degraded by the 26S proteasome, whereas those containing K63
linked chains may undergo a number of different outcomes, including trafficking and/or
lysosomal degradation. Recent work demonstrates that polyubiquitin chains through six of the
seven Lys residues in ubiquitin (with the exception of K63), can target proteins for degradation.
3 This study also showed that substrates linked through K11 chains are targets of endoplasmic
reticulum-associated degradation (ERAD) pathway.3
The HECT ubiquitin-protein ligases
The specificity of ubiquitylation system is critical and is largely regulated by the E3s, which
are responsible for mediating the transfer of ubiquitin from E2 to the substrate. Given that many
cellular proteins are ubiquitylated, there are over 600 putative E3s in mammals. There are two
main classes of E3s; the RING (Really Interesting New Gene) E3s, and the HECT
(Homologous to E6-AP C-Terminus) E3s.4 The HECT ligases accept ubiquitin from an E2
and is then transferred to the substrate. On the other hand RING E3s mediate the E2-substrate
interaction to facilitate the transfer of ubiquitin directly from an E2 to the substrate. Most human
E3s belong to the RING family, whereas HECT family consists of 28 proteins. HECT is an
~350 amino-acid domain that was first described in E6AP (human papilloma virus E6
Associated Protein).5 Although a number of proteins containing HECT domain, including the
Sacchromyces cerevisiae protein, Rsp5, and the mouse Nedd4 (neural precursor cell-expressed
developmentally downregulated gene 4), were deposited in the public databases around the
same time when E6AP was cloned,6,7 the function of the HECT as a ubiquitin ligase only
became apparent from studies on E6AP.5,8 E6AP binds human papillomavirus (HPV) E6
oncoprotein and acts as a ubiquitin ligase for p53 in HPV infected cells.9 HECT domains are
usually found at the C-termini of proteins. It is a bilobal domain, in which the two lobes are
bridged by a flexible hinge loop.10 The E2 binds to the N-terminal lobe, opposite to the C-
terminal lobe, which also carries the catalytic Cys residue. Substrate binding is defined by
regions outside the HECT, in most cases, towards the N-terminus of the protein. Based on
domain architecture, majority of the HECT E3s belong to two families: the Nedd4 family and
the HERC family.4
Nedd4 and Nedd4-2
The Nedd4 family contains nine members in human including NEDD4, NEDD4-2 (NEDD4L),
ITCH, SMURF1, SMURF2, WWP1, WWP2, NEDL1, and NEDL2.11-13 Nedd4 and Nedd4-2,
the subjects of this review, are most closely related to each other. The phylogenetic analysis
of these proteins from various species (Figure 1a) indicates that Nedd4 is the likely ancestral
member of the family, whereas Nedd4-2 originated later in evolution, perhaps by gene
duplication. Thus, Nedd4 is closely related to Rsp5 in S. cerevisiae, which has only a single
member of the Nedd4 family. There are four members of the Nedd4 family in Drosophila
melanogaster, including dNedd, but there are no Nedd4-2 orthologues (Figure 1). All
vertebrates appear to have both Nedd4 and Nedd4-2 genes. Nedd4 and Nedd4-2 have identical
specificity for ubiquitin conjugating enzymes (E2).14 The prototypic member of the family,
Nedd4, was discovered as a developmentally regulated gene in the central nervous system of
mouse.6,15 It contains an N-terminal calcium/lipid and/or protein binding C2 domain, 3 (in
mouse and rat) or 4 (in human) WW domains (protein–protein interaction domains), and a C-
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terminal HECT domain (Figure 1b). This modular domain structure is characteristic of all the
Nedd4 family members, the only variable being the number of WW domains, with the
mammalian Nedd4 family members containing 2–4 of these domains.12,13,16 WW domains
are the main determinants of substrate binding by the Nedd4 E3s, although other regions, such
as the C2 domain of Nedd4, can also bind substrates.17 Given the presence of multiple WW
domains in Nedd4 and Nedd4-2, these E3 can potentially interact with several substrates (or
regulatory proteins). The Nedd4 and Nedd4-2 WW domains can bind PPxY (PY) or LPSY
motifs, and in vitro studies suggest that WW3 and WW4 of both proteins bind PY motifs in
the key substrates, with WW3 generally exhibiting higher affinity.11,16,18,19 Most Nedd4
family members, especially Nedd4-2, also have multiple splice variants, which might play
different roles in regulating their substrates.20,21
Nedd4 targets and function
The first described target of Nedd4 was the epithelial sodium channel (ENaC).22 However,
after the discovery of Nedd4-2, it was suggested that Nedd4 and Nedd4-2 probably have
redundant functions in ENaC regulation.23-25 Subsequently, a number of potential substrates
for Nedd4 have been described and a partial list of these is shown in Table 1. Many of these
targets have been identified by the use of heterologous or in vitro systems, thus their functional
significance in vivo remains to be fully explored. Here we discuss the main pathways/targets
regulated by Nedd4.
Growth factor receptor regulation by Nedd4
Nedd4 has been implicated in the downregulation of growth factor receptors through
biochemical analyses of cells transfected with Nedd4.26 Many types of receptors have been
studied, including epidermal growth factor receptor (EGFR),27 vascular endothelial growth
factor receptor-2 (VEGF-R2),28 insulin receptor, and IGF-1R.29 However, the gene knockout
(KO) studies indicate that one of the main in vivo functions of Nedd4 is the regulation of
IGF-1R, and perhaps insulin receptor (IR).30,31 The predominant phenotype of Nedd4 KO mice
is growth retardation (with a body weight less than 40% of that of wild type littermates), and
associated perinatal lethality.30 Consistent with the overall growth retardation, mouse
embryonic fibroblasts (MEFs) isolated from Nedd4 KO embryos show slower growth, and
respond poorly to serum after serum starvation than cells isolated from wild type embryos.30
Both IGF-1R and IR signaling are affected by Nedd4 deficiency. Three lines of evidence
conveyed this point. (i) Both MAPK and PI3K signaling pathways were diminished in the
Nedd4-/- cells when stimulated with IGF-1 or insulin, with PI3K pathway affected more
severely; (ii) cell surface expression of IGF-1R and IR were reduced in the Nedd4 KO cells;
and (iii) Nedd4 action was mediated by Grb10.30 Grb10 has been shown previously to interact
with Nedd4.26 However, earlier studies, in contrast to the KO mouse data, suggested that Grb10
acts as an adaptor for Nedd4 to ubiquitylate IGF-1R.32 The mouse KO data indicate that Grb10
levels are elevated in Nedd4-/- MEFs,30 although Grb10 is not a direct target of the Nedd4-
mediated ubiquitylation.30 It is important to note that the lethality in Nedd4-/- mice was
partially rescued by maternal inheritance of a disrupted Grb10 allele.30
The interactions between Nedd4 and IGF-1R/IR appear to be receptor specific. The signaling
cascade propagated from a distinct transmembrane tyrosine kinase receptor, EGFR, was not
affected in the Nedd4-/- MEFs.30 Therefore, it is unlikely that Nedd4 serves as a ubiquitous
component of the endocytic machinery for all growth factor receptors.
It is clear from these physiological and cellular studies that Nedd4 is a positive regulator of
growth and proliferation, especially during embryonic development, through interactions with
IGF-1R/IR; however, the details of these interactions are still not clear. As other ubiquitin
ligases, such as Mdm2 and c-Cbl,33,34 in addition to Nedd4,32 have been implicated in
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mediating ubiquitylation of IGF-1R, two models of potential interaction have been proposed
and are being tested: sequential ubiquitylation and competing ubiquitylation (Figure 2). In the
first model, Nedd4 does not directly ubiquitylate IGF-1R, but controls the activity of another
E3 (Mdm2, c-Cbl, or another ubiquitin ligase), which in turn is responsible for IGF-1R
ubiquitylation and degradation. In the competing ubiquitylation model, both Nedd4 and the
other E3 directly ubiquitylate IGF-1R; however, Nedd4-mediated IGF-1R ubiquitylation does
not lead to its degradation through the proteasome. Both models can explain the current result
that Nedd4 deficiency results in increased endocytosis of IGF-1R and reduced IGF-1 signaling.
Regulation of T-cell function by Nedd4
The potential involvement of Nedd4 in T-cell activation was first suggested by Heissmeyer et
al.35 In this study it was concluded that Itch, a closely related family member of Nedd4, and
possibly Nedd4, contribute to T cell anergy – a state of T-cell unresponsiveness induced when
T cells are stimulated through the T-cell receptor in the absence of co-stimulation. The authors
showed that unresponsiveness occurs, in part, because PKCθ and PLCγ1 are degraded by a
ubiquitin-dependent process. The role that Nedd4 played in this process was not entirely clear,
and because of the high degree of similarity between Itch and Nedd4, it was suggested that
they have overlapping functions.36 However, Itch and Nedd4 deficient mice exhibit different
phenotypes, suggesting that these two E3-ubiquitin ligases regulate distinct pathways in vivo.
As mentioned earlier, mice lacking Nedd4 are perinatal lethal due to a severe growth
retardation.30 To study the role of Nedd4 in T cells, fetal liver chimeras (Nedd4-/-FLCh) in which
Nedd4 was only deficient in cells of hematopoietic origin were generated.38 Mice lacking
Nedd4 (Nedd4-/-) displayed normal T-cell development in the thymus, but their T cells in the
periphery were hypo-responsive. Nedd4-/- T cells proliferate poorly in response to antigen and
are less likely to produce IL-2. Furthermore, their B cells undergo class switching with lower
frequency.38 In contrast, mice lacking Itch have hyper-responsive T cells 39 that are skewed
towards T-helper type 2 (Th2) cytokine production. This is due to the well-described role for
Itch in ubiquitylation of JunB, a transcription factor that promotes Th2 cytokine production.
From these results, it was reasoned that Nedd4 likely promotes T-cell activation and
enhancement of the adaptive immune response, whereas Itch prevents Th2 differentiation. The
dissimilarities seen between the immunologic phenotypes of Nedd4-/- and Itch-/- mice suggest
that these E3 ligases ubiquitylate unique targets and thus, function quite differently in the
regulation of T cell responses. Thus, while the Th2-mediated disease in Itch mutant mice can
be explained by the loss of Itch-mediated degradation of JunB, it was found that the diminished
activation of Nedd4-/- T cells can be explained by the lack of ubiquitylation and degradation
of Cbl-b. Nedd4-/- T cells contained increased levels of Cbl-b protein because Nedd4 is needed
for the polyubiquitylation of Cbl-b.38,40 Although these data support that these two E3 ligases
act on a unique subset of targets, further studies are needed to address whether this is true for
all Nedd4 and Itch targets, or whether these ligases share the responsibility of ubiquitylating
some targets.
Nedd4 regulates neuromuscular junctions
In addition to the phenotypes of Nedd4 KO mice described above, a recent study of the
Nedd4-/- embryos indicate that this E3 is also needed for the proper formation and functioning
of the neuromuscular junctions.41 Nedd4 is highly expressed in skeletal muscle. In Nedd4-/-
embryos the size of skeletal muscle fibers and the number of motor neurons were reduced,
even though, very interestingly, Nedd4 is not expressed in motor neurons. This suggests that
the function of Nedd4 in this system is non-cell autonomous. A detailed analysis indicated that
Nedd4 regulates the interaction between the motor neurons and the muscle, especially nerve
fasciculation. In the KO embryos, the pre-synaptic nerve terminal branches at the
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neuromuscular junctions are reduced in diameter but increased in number.41 Although these
studies clearly define an important role of Nedd4 in regulating neuromuscular junctions, the
mechanism by which this occurs remains unknown. Furthermore, it is unclear whether the
motor neuron and skeletal muscle fiber phenotypes are directly due to the defective regulation
of the formation and functioning of the neuromuscular junctions. The discovery of the substrate
(s) of Nedd4 responsible for these phenotypes in the Nedd4 KO mice will delineate the precise
mechanisms by which Nedd4 controls the size of skeletal muscle fibers and the number of
motor neurons.
Regulation of VEGF-R2 by Nedd4
Another potential target of Nedd4 is VEGF-R2.28 In this system Grb10 protein is a positive
regulator of VEGF signaling; VEGF enhances Grb10 expression, and Grb10 overexpression
induces increased Tyr phosphorylation of VEGF-R2 and increased accumulation of this
protein.42 A study by Murdaca et al. 28 found that Nedd4 mediates VEGF-R2 degradation and
Grb10 inhibits this by binding to Nedd4. It is interesting to note that although VEGF-R2 is
ubiquitylated, Nedd4 does not directly mediate this ubiquitylation. Given that Nedd4 KO mice
accumulate Grb10,30 it will be interesting to study whether the loss of Nedd4 leads to increased
VEGF-R2 protein and a deregulation of vasculogenesis and angiogenesis.
Does Nedd4 play a role in the regulation of PTEN?
It was previously reported that PTEN is ubiquitylated and degraded in the cells, and
biochemical purification using HeLa cell lysate showed that Nedd4 was the putative E3
responsible for PTEN ubiquitylation43 and nuclear localization.44 As PTEN is one of the major
tumor suppressor genes, these reports suggested an important role for NEDD4 as an oncogene.
43 In supporting the role of Nedd4 in regulating PTEN, it was shown that Nedd4 is upreguated
in certain type of tumors when compared with nearby normal tissue.44 As the interaction
between Nedd4 and PTEN was based largely on studies using heterologous expression system
with either Nedd4 or Nedd4 and PTEN both overexpressed in cultured cells, it prompted the
testing of this interaction in Nedd4 deficient cells from gene KO mice. Independent studies
from a number of Nedd4 KO lines have failed to detect changes in the amount of PTEN in
MEFs.30,31,38 In addition the stability and localization of PTEN were not affected by the
absence of Nedd4.31,38 Furthermore, the results obtained using siRNA knockdown of Nedd4
presented in the earlier reports 43,44 could not be reproduced.31,38 Overall, these results argue
against a general role of Nedd4 in PTEN stability and localization. However, to fully resolve
this controversy, additional work may be needed, for example, to establish if Nedd4 has any
cell-type specific function (such as in human tumor cells) in PTEN regulation.
Regulation of viral budding by Nedd4
Once mammalian cells are infected with viruses, virus replicates within the cells and exhausts
the host cells to make viral progenies. The progenies leave the host cells via several routes,
and one of them is called viral budding.45 Nedd4 and Nedd4-like proteins (including Nedd4-2)
have been implicated in this process for many viruses including the Epstein–Barr virus,46
retrovirus,47 and Ebola virus.48 These viruses contain motifs that interact with Nedd4 or
Nedd4-2 WW domains, leading to the ubiquitylation of viral matrix protein and recognition
by the cellular ESCRT machinery. One of the best described viral proteins involved in Nedd4
interaction is the latent membrane protein 2A (LMP2A) of the Epstein–Barr virus.46 Through
the PY motifs at its N-terminus LMP2A recruits the Nedd4 family of E3s, leading to the
ubiquitylation of LMP2A and LMP2A-associated proteins, such as Lyn.46 Ubiquitylation of
viral proteins serves as a signal for trafficking through the host cell's vesicular transport
machinery, however the precise mechanisms of viral egress are not fully understood.
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Algae bloom behind Klamath dam | James Norman The rivers of the Pacific Coast once teemed with wild salmon, providing nourishment for humans, wildlife, and ecosystems from the mountains to the sea—including many communities of orca whales. But for the last century, dams, habitat loss, and excessive harvest have pushed salmon to the brink. Dams… Read more »
The most anti-environmental piece of legislation in history
Just after 4:30 a.m. this past Saturday, the U.S. House of Representatives passed arguably the most anti-environmental piece of legislation in history. H.R. 1, which would fund the government through the rest of federal Fiscal Year 2011, eviscerates programs that protect our drinking water, clean up polluted rivers, and safeguard land and wildlife for future generations…. Read more »
Restoring the Yuba River
Guest post by Steve Rothert, American Rivers' California Field Office Director The fight to restore the Yuba River and restore salmon and steelhead runs to the upper Yuba has entered a new phase. The Yuba County Water Agency recently started the process to obtain a new operating license from the Federal Energy Regulatory Commission (FERC)… Read more »
Rivers of a Lost Coast
Our Board members continue to help spread the word about the importance of healthy rivers and the harmful consequences communities face when their rivers are damaged. Most recently American Rivers Board member Tom Skerritt lent his acting skills to the new documentary Rivers of a Lost Coast. The film examines the history of the fly… Read more »
Sediment Behind Klamath River Dams Not Harmful
On August 12, federal scientists released data indicating that sediment stored behind the Klamath River dams targeted for removal do not pose a threat to communities or the river. Scientists tested for mercury, PCBs, dioxins, and other harmful substances. You can read the data from the latest study here. This federal study confirms the findings… Read more »
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There are tens of thousands of rivers and streams across our country, and each year only ten make it on to the America's Most Endangered Rivers list. For 25 years America's Most Endangered Rivers has been our most highly anticipated report. The 2010 list, released today, spotlights rivers facing a multitude of threats from New… Read more »
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In 2008, American Rivers' work led to unparalleled successes. Though we had many to pick from, we managed to come up with a list of our top 8 successes this year. Here they are (drumroll, please…): 1. Commemorating our 35 anniversary protecting and restoring the nation's rivers to benefit people, wildlife and nature. 2. Negotiating… Read more »


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Pinging in an engine is the result of the air and fuel mixture within an engine cylinder igniting incorrectly, explains Cars Direct. This may be caused by using gasoline with an insufficient octane rating, carbon buildup within the cylinder itself or improperly functioning spark plugs.Know More
When the fuel/oil mixture within an engine cylinder combusts, it normally does so in a progressive fashion rather than igniting all at once. This allows the force of the ignited fuel to provide controlled pressure on the piston, resulting in even thrust. If the ignition stutters or the gas ignites all at once, this creates a pinging sound and puts undue stress on the piston and cylinder, reducing performance and decreasing the life of the engine.
High-octane gas is designed to prevent preignition of the air/fuel mixture. Using a higher-octane gas than normal can reduce pinging. Carbon buildup on the cylinder wall can also cause improper ignition and pinging. All U.S. gasoline contains detergents. Adding a detergent to fuel often helps clear out accrued deposits; additive detergents can be found at automobile supply stores. Faulty spark plugs can also cause improper ignition. If pinging persists, visit a mechanic to verify all spark plugs are in proper working order.Learn more about Engine
Engine braking is a method of slowing a vehicle down without using external braking mechanisms, such as friction brakes or magnetic brakes. Engine braking refers to the braking effect caused by the closed-throttle partial vacuum in petrol engines when the accelerator pedal is released.Full Answer >
A stroker engine has an increased piston stroke over the factory engine, which leads to more displacement and subsequently more torque. This is achieved by increasing the throw of the crankshaft, increasing the length of the connecting rod, and decreasing the compression height of the piston.Full Answer >
Engine knock can be caused by an incorrect air/fuel mixture within one or more cylinders. The knocking sound is the fuel burning unevenly and creating shock waves at the wrong times. The waves can damage the cylinder wall as well as the piston.Full Answer >
EcoBoost is a line of engines developed by Ford Motor Company, which they began manufacturing in 2010. EcoBoost engines use a combination of direct fuel injection, variable camshafts and a turbocharger to provide increased fuel efficiency without sacrificing anything in terms of torque, horsepower or overall performance.Full Answer >


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They have 2 liter cold Diet Dr Peppers! Also the first scene from Superbad (slushie scene) filmed here.
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BedandBreakfast.com Diamond Collection
Professionally Inspected & Certified
Come relax at Butterfly Meadows Inn & Farm where we have created a place for you to surrender your stress and unwind. You will start to soak in the tranquility as soon as you turn into the meadows. Follow the winding wooded drive up to the hill top and a peaceful state of mind.
We specialize in making each guest feel special. Your spacious accomodations include a scrumptious breakfast and a full measure of relaxation. You will feel at home in rooms beautifully appointed for your comfort. Every detail is designed for your enjoyment and relaxation.
We offer a huge selection of games & puzzles, an Apple TV library with over 700 titles, a book library with over 5,000 volumes, a large rocking chair porch, nature trails, stunning panoramic views and many quiet getaway spots. There are several beverage stations throughout the inn for unlimited coffees, teas and hot chocolates and bottled water.
Come experience why our motto is Relax ~ Breathe ~ Create!
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Score Breakdown based on10 Reviews
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on September 23, 2014
Very beautiful and relaxing. Stayed here for an anniversary retreat and it was lovely. Will be visiting again!
on August 04, 2012
Beautiful, spotless Inn. The innkeeper, Darlene is a great host and Heather cooks a breakfast beyond belief! This is the place to stay if you are in the Franklin / Nashville area.
on December 13, 2011
Love the warm hospitality, the gorgeous views, the delicious food, the amazing library - the whole delightful experience at Butterfly Meadows!
on December 13, 2011
We had a lovely night of relaxation with friends! Beautiful back porch with gorgeous view!
on December 11, 2011
The Inn was a wonderful break from the day to day. We enjoyed the beautiful surroundings and the wonderful accommodations. The room was very comfortable and we enjoyed sipping coffee on the rocking chair porch. The food was delicious and the inn keepers very friendly. It was a wonderful break and very rejuvenating. We would go back at any opportunity.
on December 10, 2011
I stayed at Butterfly Meadows for a ladies retreat, and it was fabulous! First of all, the staff is incredible, and the owners are some of the nicest people you'll ever meet. The Inn is beautifully furnished. The rooms have warm, beautiful quilts on the beds. I would definitely choose to stay here again!
on December 08, 2011
I have stayed a single night on two different occasions at Butterfly Meadows, and both times were absolutely wonderful! My room was spacious, clean, and beautifully decorated. The bathroom was very spacious and clean as well. The hilltop setting is quiet, and the views from any direction are breathtaking! I especially loved the unique and locally made rocking chairs on the back porch. The food was delicious and plentiful, and the owners and staff welcomed everyone warmly. I think they truly enjoy meeting people and making them feel at home. I would definitely recommend this inn to anyone looking for peace, relaxation, and a little bit of pampering.
on November 08, 2011
We stayed at Butterfly Inn for two nights while visiting Nashville and the surrounding area. The location is excellent as it is a true country setting yet close enought to the city to enjoy the urban attractions. We found the Inn very comfortable and the innkeeper was very accomodating to our schedule. The spacious room was well furnished and provided great views. The bathroom was very large and modern with plenty of space and easily accessible shower. Defintely a place we would recommend to others.
on October 02, 2011
My husband and I spent our anniversary here and we enjoyed it very much. It was a quiet getaway from everything and everybody. Our room was very spacious and comfortable. Our breakfast was delicious and plentiful. The staff was awesome
on July 17, 2011
We spent two nights in the Butterfly Inn and it was wonderful. We felt like family when we left. The Innkeepers went out of their way to make us comfortable. All the staff are very welcoming and very personable. The breakfast was delicious, too!! The reason the room only got 3 stars is because we didn't have a double vanity bathroom and the bed linens are not "plush". Besides that...great place to stay!!
Innkeeper ResponseThanks for your great comments! We are pleased that you enjoyed your stay. Please let us know the next time you travel our way that you would like a double vanity. Most of our rooms do have antique-style dresser double vanities.
We know that furnishings are important. In keeping with our farmhouse atmosphere, we have chosen fine quilts, matelesse and trapunto bed coverings. Many of these have actually been made by local artisans. We hope these help give our rooms a uniquely welcoming feel. Our aim is always for maximum guest comfort. We only use high thread count cotton linens, seasonal blankets and piles of pillows atop a premium mattress.
Let us know if you have a favorite amenity and we'll try to include it next time!
View More Reviews
Nashville, TN (BNA) 29 miles
Off TN-840 Exit 34. Download a PDF map & directions from our website.
Bed and Breakfast, Country Inn
BBQ grill, Bath robes, Board games, CD player, Ceiling fans, Conference Rooms, Copier, Fireplace, Library, Piano, Telephone, Videos, Wedding Facilities, Wet bar, Wired internet ,
Nature Trails, Gift Baskets by request, Gift Certificates, Rocking Chair Porch, Private Meeting & Event Facilities
Air conditioning, Alarm clock, Amenities Basket, Coffee/Tea facilities, DVD Player, Desk, Hairdryer, Internet Service, Ironing Board, Radio, Satellite/Cable TV, TV, Turndown Service, Wi-Fi
Darlene & Norman Bobo
Low fat , Restrictive , Vegetarian , Gluten Free
$229 per night
Check Availability
Innkeepers: Darlene & Norman Bobo
Guests: 2
Simple! BedandBreakfast.com guarantees you're getting the best price on your bed and breakfast stay when you book your room on BedandBreakfast.com. Within 24 hours of your booking, if you find a better price for the same room on the same date(s) at the same B&B, BedandBreakfast.com will refund the difference to you!
The Best Price Guarantee covers any Bed and Breakfast booked online through BedandBreafkast.com. The Bed and Breakfast must be booked using the Book It button on BedandBreakfast.com in order to qualify.
Just call 1-512-322-2710 within 24 hours of booking and give our customer support representative the details on the lower price you found.
The BedandBreakfast.com Best Price Guarantee ensures that when you book and pay for your reservation online through the BedandBreafkast.com website, you are booking your room at the lowest available price. If you find a lower price for the same room on the same dates at the same B&B, and contact us within 24 hour of making your booking, we will refund the difference in price to you. This guarantee does not apply to bookings made over holidays and/or for special events. All requests are subject to verification by BedandBreakfast.com. BedandBreafkast.com will not accept screenshots or other purported evidence of a lower price that cannot be independently confirmed by BedandBreakfast.com personnel. Nor will BedandBreakfast.com verify any requests that it believes, in its sole discretion, is the result of a printing or other error or is made fraudulently or in bad faith.


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On June 1, 2013 House Bill 695 will take effect in Maryland. The bill, although the title seems harsh, does not eliminate or prohibit the inclusion of the Anti-Concurrent Causation Clause in the homeowner's insurance policies. The bill requires that an insurer that issues a policy of homeowner's insurance to provide notice of the inclusion of the clause to a policy holder each year. The notice must:
1. be clear and specific;
2. describe the Anti-Concurrent Causation Clause;
3. describe the manner in which the Anti-Concurrent Causation Clause may be applied by providing at least one example;
4. inform the insured to read the policy for complete information on the exclusion;
5. state that the insured should communicate with the insurance producer or the insurer for additional information regarding the scope of the exclusion.
This will place an additional responsibility on underwriters at the issuance of new and/or renewal policies. It will provide the insured notice of the existence of the clause and information on how it is applied.
See more »
DISCLAIMER: Because of the generality of this update, the information provided herein may not be applicable in all situations and should not be acted upon without specific legal advice based on particular situations.
© Niles, Barton & Wilmer, LLP
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Astro Boy TV Show Watchlist
Animated tales of a robotic boy in the 21st century.
Rating: TV-Y
Latest Full EpisodesSee all »
Dr. Elefun and Astro Boy are sent back to 10th-century England, where they become contestants in a joust. Astro Boy emerges as the winner and the favorite of King Canute and Princess Lydia.
Atomic submarine trains, supersonic passenger planes, and whole communities are demolished by the monstrous Dunder Bird. After each attack, Dunder demands Astro Boy's surrender.
Astro Boy experiences first-hand the effects of a machine that allows robots to have dreams. While Astro Boy dreams, a villain named Mr. Nightmaroo tries to steal the Dream Machine.
Professor Jingo develops a remarkably humanized little animal named Minute with a prophetic sixth sense that allows him to know of things that will happen before they transpire.
Cast & Details See all »
- Rating: TV-Y
- User Rating:
- Premise: Animated tales of a robotic boy in the 21st century. (more)
Trending TonightSee all »
Doctor Who9:00 pm | BBCI'll Watch164 Watching
The Last Kingdom10:00 pm | BBCI'll Watch142 Watching
NASCAR Sprint Cup Series: From Concord, N.C.7:15 pm | NBCI'll Watch112 Watching
Astro Boy - The Complete Series
By Sony Pictures Home EntertainmentBuy New: $8.05
Astro Boy - Ultra Collector's Edition DVD Set 1
By Bayview Entertainment/WidowmakerBuy New: $84.49
Astro Boy and Anime Come to the Americas: An Insider's View of the Birth of a Pop Culture Phenomenon
By McFarlandBuy New: $35.00
Popular Shows
- 1. Blindspot
- 2. Quantico
- 3. Rosewood
- 4. Limitless
- 5. Code Black
- 6. The Player
- 7. Life in Pieces
Popular Movies
- 1. Straight Outta Compton
- 2. Ant-Man
- 3. Southpaw
- 4. Trainwreck
- 5. Minions
- 6. Vacation
- 7. Mission: Impossible - Rogue Nation
Popular Celebrities
- 1. Priyanka Chopra
- 2. Bindi Irwin
- 3. Selena Gomez
- 4. Melissa Benoist
- 5. Jaimie Alexander
- 6. Rami Malek
- 7. Bryshere Y. Gray


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Panasonic Lumix DMC-GH1
The Lumix GH1 is a micro four-thirds SLR with a 12.1 megapixel Live MOS sensor. It builds on the model of its predecessor, the G1, by adding 1080p HD video recording.
- Exellent 1080p video
- Articulated Live View LCD
- Great kit lens
- Expensive
- Fewer lenses available
- Not a true DSLR
Read Our Full Review: Panasonic Lumix DMC-GH1 Review
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With 1.7 million freelancers, we'll match you with the perfect talent.
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I have some box label files that I need edited.
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(I do NOT have ALL the .PSD files)
I need all files edited to remove old company information, name and logo and to be replaced with new company information, name and logo.
There is 2 sets of files, singles and printables. I will attach examples.
We require all files in JPEG & PDF format, we also require the raw edited files (ie… .PSD, .AI, etc…)
I will attach samples of the label files JPEG, .PDF, and .PSD.
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"Skinback" at the Los Angeles Times
Jill Stewart weighs in on the Rathergate of the West Coast:
The amazing Page One Los Angeles Times article today, correcting a probably libelous Times Calendar story published on St. Patrick's Day and written by investigative reporter Chuck Philips, is known in the journalism biz as a "skinback." I don't know exactly where the term "skinback" originated, but you could feel the skin getting peeled off Philips piece by piece in the retraction by Jim Rainey. It describes how Philips got duped by con artist James Sabatino into running a false story that implicated Sabatino himself, as well as associates of Sean "Diddy" Combs, in the non-fatal but brutal 1994 shooting of the late rapper Tupac Shakur.
Apparently, five-time loser Sabatino was so desperate to entangle himself in the lives of famous rappers that he created the fake FBI document on an old typewriter, implicating himself and talent manager James Rosemond. Chuck Philips bought it, writing that Rosemond and Sabatino "set up the rapper Tupac Shakur to get shot at Quad Studios," and then connected them to Combs' Bad Boy Records.
But the document was filled with dead-giveaways that it was a fake, which any independent documents expert could have told the Times. Credit goes to The Smoking Gun for ripping the lid off this putrid mess. There were problems with the Philips story even before The Gun went off.
It was so jammed with off-record sources it read like a piece from the Bad Old Days before corrupt journalist Jayson Blair so badly dirtied The New York Times. Today, among the nation's big dailies, the L.A. Times has one of the most useless policies for controlling its overuse of unnamed sources, which proliferate there like a plague. Take away the anonymous sources, and Philips' entire story turned on a bogus document.
Have you noticed the outrage from media ethics mavens across the country?
Yeah, cue the chirping crickets.
Actual WaPo headline: Why our technological ignorance is hurting Hillary Clinton
October 9, 2015 01:42 PM by Doug Powers
The Sundance Kidder: Global warming alarmist Robert Redford says deniers are 'afraid of change'
September 18, 2015 01:46 PM by Doug Powers
Thursday open thread: Hillary talks gun control in wake of Va. shootings; Pentagon conforms ISIS threat to match WH narrative
August 27, 2015 08:37 AM by Doug Powers
The video of Carly Fiorina TKOing Hillary & Tingles should be required viewing for the GOP field
August 7, 2015 02:02 PM by Doug Powers
Sound familiar? Democrats blame people who made a video for horrific acts of others
July 22, 2015 10:06 PM by Doug Powers
Categories: 2016 Campaign, Abortion, Democrats, New York Times


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Johann Sebastian Bach
1 of 2 portraits of Johann Sebastian Bach
Johann Sebastian Bach
by Conrad Cook, published by William Mackenzie, after Lazarus Gottlieb Sichling, after Elias Gottlob Haussmann
line and stipple engraving, circa 1840-1850
10 3/8 in. x 6 7/8 in. (262 mm x 175 mm) paper size
Bequeathed by (Frederick) Leverton Harris, 1927
Reference Collection
Click on the links below to find out more:
Sitterback to top
- Johann Sebastian Bach (1685-1750), Composer. Sitter in 2 portraits.
Artistsback to top
- Conrad Cook (active 1831-1850). Artist associated with 7 portraits.
- Elias Gottlob Haussmann (1695-1774). Artist associated with 1 portrait.
- William Mackenzie (active mid 19th century), Publishers. Artist associated with 4 portraits.
- Lazarus Gottlieb Sichling (1812-1863), Engraver. Artist associated with 3 portraits.
Subjects & Themesback to top
Tell us moreback to top
Can you tell us more about this portrait? Spotted an error, something missing, or do you know anything that we don't know? If you have any information to share please complete the form below


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Stefani Pollack of Cupcake Project is a food (or should we say dessert?) blogger in St. Louis, Missouri, where she lives with her husband and son. She has been baking and blogging since 2007, when she left the corporate world to be a full-time mom, writer, photographer, conference planner and recipe developer. Stefani can usually be found hula-hooping or baking something new in the kitchen, but she's also on Facebook, Twitter, Pinterest and Google+.
All winter long, my son tries to spot bunnies in an empty neighborhood field. "Soon," I tell him. "We need to wait for spring." When spring comes, we hop up and down (like the bunnies) and stare as the fluffy-tailed creatures scamper about.
Bunny sightings lead to talk of carrots, which leads to my carrot cupcakes (with a blog called Cupcake Project, it shouldn't surprise you that I typically make cupcakes rather than cakes). This year, however, I'm on a pie kick. Cupcakes are fun, cute, and sometimes sassy, while pies are typically homey, comforting, and full of love. So, I decided to make carrot pie.
I fashioned my carrot pie after sweet potato pie (my all-time favorite pie), using roasted carrots instead of pureed sweet potatoes. However, I wanted to pull one of carrot cake's best elements, the cream cheese frosting, into the pie. To accomplish this, I gave the pie a cheesecake layer.
If you didn't guess from the fact that I tackled carrot pie, I'm not the most traditional pie maker. One of my favorite areas of pie baking is experimenting with the crust (I recently baked a crust made out of potato chips). I gave the carrot pie a pecan and brown sugar crust with a touch of ginger and lemon. Even if you don't try the carrot pie, I'd suggest trying this crust. It would be a wonderful foundation for apple pie.
The Hamilton Beach Stack & Snap™ 10 Cup Food Processor made baking this pie a breeze. I used it to puree the roasted carrots (it's so fun to drop them down the chute and watch them whiz around the bowl). I also used the food processor to chop the pecans – the food processor is a major time saver.
Whether you are cooking for two or prepping a large family meal, the Hamilton Beach® Stack & Snap™ 10 Cup Food Processor takes the guesswork out of food processing with a simple function guide that shows you which blade to use and which button to press. Designed to be uniquely simple – there's no twisting, turning or locking required when assembling the food processor.
TAGS: Cupcake Project, dessert, pie, Stefani Pollack
CATEGORIES: Center Stage, dessert, Everyday Recipes


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This profile was last updated on 7/14/14 and contains information from public web pages and contributions from the ZoomInfo community.
Anakkarat Tubtim BarthWrong Anakkarat Tubtim Barth?
Director of Global Programs and P...
Phone: (213) ***-****Email: a***@***.edu
University of Southern California
700 Childs Way
Los Angeles , California 90089
United States
Company Description: Established in 1880 and located in the heart of Los Angeles, the University of Southern California (USC) is one of the world's leading private research... more
Pro2015_Iteration9_NoTests.148[05] SEIDXWK-41


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Best Schools in Barney Circle
St. Coletta Special Education PCS
Charter • Grades PK-12 & ungraded
250 students • 1 student/teacher
Which schools are assigned to my home?
About Barney Circle Schools
Barney Circle contains 1 primary and secondary schools.
School Districts Near Barney Circle
Disclaimer: School attendance zone boundaries are supplied by Maponics and are subject to change. Check with the applicable school district prior to making a decision based on these boundaries.


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Q&A: Shigeru Miyamoto On The Origins Of Nintendo's Famous Characters
Shigeru Miyamoto created many of Nintendo's iconic video game franchises. In an NPR interview, he spoke about how his famous characters came to be and how his life experiences inspire his creations.
The Legendary Mr. Miyamoto, Father Of Mario And Donkey Kong
Super Mario Bros. turns 30 this year. NPR's Laura Sydell met up with the video game's famed creator, Shigeru Miyamoto, who was in Los Angeles this week at the Electronic Entertainment Expo.
Battle Over New Oil Train Standards Pits Safety Against Cost
Against the backdrop of several fiery derailments, safety advocates are questioning whether new federal rules meant to prevent incidents go far enough. Opponents say the new rules are too costly.


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December 22, 2011
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All Comments (16)
sexy feet
fucking ride!
What is her name!!!!!????
isn't he about the goofiest looking bastard
Very lovely, ultra-sexy - great!!!
zora banks is the name
milf but fuck it! I'd hit that
Whats her name?
this is my favorite of the suck my toes series
I want to know that lady... I love her feet
she is zora banks
f*ck her toes
came @ work to this....


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Eight Must-See Movies & Events at the Plaza Classic Film Festival This Weekend
The Plaza Classic Film Festival comes to an end this Sunday, but before then, here are eight movies and events that you must attend before its conclusion.
The Plaza Classic Film Festival comes to an end this Sunday, but before then, here are eight movies and events that you must attend before its conclusion.
Let's do the time warp again.
Annual event to screen movie on the ballpark's giant high-definition scoreboard.
Classic film fanatics in El Paso are waiting on pins and needles to hear "Frankly, my dear, I don't give a damn" during the Plaza Classic Film Festival next month can also check out a coordinating exhibit at the El Paso Museum of Art.
Plaza Classic Film Festival organizers announced Tuesday that Cindy Williams from the classic TV show 'Laverne & Shirley' along with Louise Fletcher from her famed role as 'Nurse Ratched' in 'One Flew Over the Cuckoo's Nest', will be this year's celebrity guests.
The El Paso Community Foundation's Plaza Classic Film Festival marks the return of the Civil War-era epic Gone With the Wind with an encore screening and a related exhibit at the El Paso Museum of History.
The new season of the Plaza Classic Film Festival has added more movie titles to the film festival with the addition of Star Trek II: The Wrath of Khan and Funny Face starring Audrey Hepburn.
The El Paso Plaza Classic Film Festival has added two summer blockbusters for this year's lineup, including Back to the Future and American Graffiti.
The black and white classic, Mildred Pierce starring Joan Crawford will be screened at Ardovino's Desert Crossing on Sunday, May 17 at noon.
The 8th Annual Plaza Classic Film Festival will be showing two different classics from 1975, five-time Academy Award-winner One Flew Over the Cuckoo's Nest and the cult British comedy, Monty Python and the Holy Grail.
El Paso loves the Chihuahuas and the Plaza Classic Film Festival, and later this summer, they're teaming up to show a classic baseball film. It's a "pre-game" warmup to the world's largest classic film festival that happens in downtown El Paso.
The Texas Archive of the Moving Image (TAMI) and their traveling Texas Film Round-Up have made their trip to El Paso once again.


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This property allows you to book online with a credit card. After submitting a reservation request, the owner or manager has 24 hours to accept, at which time your card will be charged and you will receive an email confirmation
Recent World reviews
"This was our first time staying at this beautiful condo at Ocean Keyes! It is so nice. The décor is just beautiful. It was very roomy. It was so nice to relax there. Lots of seating for hanging out and eating. The owners were amazing to work with the entire process! The pool and grill area was really nice. All the property was well kept. Quick drive to the beach, or short walk. Can't wait to go back! Can't go wrong staying here!"Guest: Wanda J. Date of Stay: July 2015 Review Submitted: July 27, 2015View listing
"The house was wonderful. Lots of space inside and out! The screened in pool was used everyday. Every morning we enjoyed our coffee by the pool The house was comfortable, clean and well equipped. We rented bikes and got around easily."Guest: Nancy G. Date of Stay: March 2015 Review Submitted: April 9, 2015View listing
"I highly recommend! The best view and walking distance from a few mom and pop restaurants and souvenir stores. Short drive from grocery store and Treasure Island Marina for different boat rides, etc. It's also at the end of the strip so there is a lot less traffic. My family had a great time. If we go back, we will most definitely stay at Treasure Island again!"Guest: Veronica R. Date of Stay: July 2015 Review Submitted: July 21, 2015View listing
"The condo was very clean and well equipped with what we needed. The instructions were nicely laid out and Zhibo was very good about checking in and making himself available (also made some great restaurant suggestions). Would highly recommend. (My only suggestion would be to have two queen beds in the basement bedroom)"Guest: Trish Date of Stay: August 2015 Review Submitted: August 17, 2015View listing
Featured Destinations: The Villages, Rosemary Beach, Destin Condo Rentals, Amelia Island, Myrtle Beach, Outer Banks


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Gio Benitez and Brad Nitz track the latest weather news across the country.
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