text:
Fatal rollover crash kills teen, injures two other teenagers.
The Richland School District is trying to stay ahead in the teacher recruiting process.
With the start of cooler weather comes the end of another wildfire season in our area. KEPR reports on the costs and trends from the 2015 fire season.
A new treatment center in Kennewick is helping people with eating disorders.
Fatal rollover crash kills teen, injures two other teenagers.
The Richland School District is trying to stay ahead in the teacher recruiting process.
With the start of cooler weather comes the end of another wildfire season in our area. KEPR reports on the costs and trends from the 2015 fire season.
A new treatment center in Kennewick is helping people with eating disorders.
A fire broke out inside of the Kennewick suites Monday. Repairs were being made on an electrical box when smoke was seen on the second and third floors
Safe Kids Benton-Franklin is looking to educate and show parents how to properly put a child in a car seat.
KEPR has confirmed the identity of the baby boy who was killed in a seven-car pileup.
Millions of people have either gotten or are considering getting the new iPhone 6S or 6S Plus. Consumer Reports has been testing these new phones and shares some of the results.
One is still in critical condition at Seattle's Harborview Medical Center, while two others are improving.
Hunting accident near Colfax leaves a Kennewick man dead. Deputies say he was shot by someone he was hunting with.
Your Photos
they were grazing in the field by our house, when we saw them, they let us get so close, we were surprised, i did use my zoom very little..
The 28-year-old Londoner, who plays menacing, white-haired Daenerys Targaryen, aka Khaleesi, aka Mother of Dragons on "Game of Thrones," is Esquire's Sexiest Woman Alive.
The magazine that helped usher in the sexual revolution in the 1950s and '60s by bringing nudity into living rooms - or at least sock drawers - all over America announced Tuesday that it will no longer run photos of completely naked women.
A rippled white gourd weighing in at 1,969 pounds took the title Monday for plumpest pumpkin at an annual San Francisco Bay Area contest.
One couple ran away to get married ... at the Chicago Marathon.
UConn students are trying to use an embarrassing video about macaroni and cheese to raise a little cheddar.
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Local & Regional
A small aircraft with a single engine that stopped working made a belly landing on Interstate 84 in Boise, Idaho, right at the start of rush hour traffic Tuesday morning.
For people with insomnia, there's a new prescription sleep drug called Belsomra. It acts differently on the brain than current medications like Ambien. Consumer Reports worked with medical experts at the Dartmouth Medical School to analyze Belsomra's effectiveness and safety.
Pasco crash on State Route 12 injuring at least four people, Troopers say drugs or alcohol were involved.
This weekend is the annual Catch the Crush Event, where 40 different wineries in the Yakima Valley participate in fun activities to engage and educate those who come.
Tapteal Greenway is celebrating 20 years through the efforts of volunteers.
Pete Carroll could have been talking about the season opener at St. Louis, or Week 2 in Green Bay, or even the Super Bowl loss last February to New England.
Southern California coach Steve Sarkisian is taking an indefinite leave of absence, athletic director Pat Haden says.
Andy Dalton led Cincinnati from a 17-point deficit to a signature win, the kind they've rarely gotten in the past. One that showed this Bengals team is indeed in a different class.
The Seattle Seahawks announced their inactives for Sunday's matchup at Paul Brown Stadium with the Cincinnati Bengals.
Around the World
A missile launched from rebel-held Ukraine smashed into Malaysia Airlines Flight 17, ripping off the cockpit, Dutch investigators reported Tuesday, adding that some passengers may have remained conscious for another minute or so as the airflow tore off their clothes.
he private email server running in Hillary Rodham Clinton's home basement when she was secretary of state was connected to the Internet in ways that made it more vulnerable to hackers while using software that could have been exploited.
A woman is suing her 12-year-old nephew in Connecticut for $127,000 for injuries she says she suffered from his exuberant greeting at his birthday party four years ago.
Two firefighters who saved two residents from a burning apartment complex in Kansas City were killed when a wall collapsed onto them after they had evacuated the building, authorities said.
A Rhode Island man who weighs nearly 800 pounds says he's determined to slim down and he dreams of becoming an actor one day.
Top Video
A follow up on a sad story that is now much happier. A German Shepherd that nearly lost her life has beaten the odds.
Getting stopped by a cop usually isn't a good thing, but for high school students in Kennewick, a new safety campaign has them getting "Caught in the Act" of doing the right thing.
Pasco Police are now looking for two males accused of being involved in Wednesday night's homicide near the Cable Bridge.
Will It Work
Click on the video tab to watch as Storm Tracker Jay Frank gets some help testing the Stomp Rocket.
Used to getting a pint when you buy ice cream? You may have to reduce your expectations: many are now just 14 ounces. Hood ice-cream sandwiches used to be packed 12 in a box. Now you get 10 for the same price. Companies often blame the rising cost of labor and ingredients for that kind of downsizing. But Consumer Reports says that it's a way for them to raise prices, too, without being noticed.
Kickstart with Kelley
Kelley heads to a local brewery in Richland to learn about Beer Choir and the ancient tradition of singing while drinking!
Michelle Obama is grooving to the tunes of Beyonce, Demi Lovato and Esperanza Spalding as she celebrates the International Day of the Girl.
Sometimes "Like" just doesn't cut it. So how about Love or Angry? Haha or Sad? Or just Yay or Wow?
The Tokyo Motor Show, opening to the public Oct. 30 at Tokyo Big Sight convention hall, will be packed with futuristic eye-catching vehicles that drive themselves, offer online information in dazzling ways and are so green they are zero-emissions.
There'll be no arguing with the driver on this bus: the rides are free and there's no driver anyway.
Amazon is launching its site for handcrafted goods called Handmade at Amazon on Thursday, hoping to capitalize on shoppers' appetite for homemade goods ahead of the holiday season.
A few days earlier, Victoria Sencerbox would have been wiped out by a walk down the hospital corridor. But two days after heart surgery, "I couldn't be happier. I really couldn't be happier," she said.
Give flu vaccine another chance: This year's version got a recipe change that should make it more effective after last winter's misery from a nasty surprise strain of virus.
A government task force says a daily low-dose aspirin could help certain people in their 50s and 60s prevent a first heart attack or stroke - and they might get some protection against colon cancer at the same time.
A tiny, wireless pacemaker could offer some heart patients a surgery-free alternative to the traditional devices, a new study says. Some doctors, however, say there are lingering safety questions and warned patients not to rush to get the new technology.
Amgen Inc. has won federal approval for the second medicine in a new class of pricey biotech drugs that reduce artery-clogging cholesterol more than older statin drugs that have been used for decades.
The world's top two beer makers agreed Tuesday to join forces to create a company that would control nearly a third of the global market and threaten to dominate the U.S. by bringing together Budweiser and Miller Genuine Draft.
Twitter is laying off up to 336 employees, signaling CEO Jack Dorsey's resolve to slash costs while the company struggles to make money.
Starbucks will start offering delivery within the Empire State Building Tuesday, giving office workers in the skyscraper the option of paying a $2 fee to avoid making a trip to the lobby.
Johnson & Johnson said Tuesday that its board of directors approved a $10 billion stock buyback plan.
China's imports fell by an unexpectedly wide margin in September in a new sign of weakness in the world's second-largest economy.
General Mills is recalling 1.8 million boxes of Cheerios and Honey Nut Cheerios produced at a plant in Lodi, California, saying the cereal is labeled gluten-free but actually contains wheat.
Fabric steamers are useful time-savers that can spiff up your wardrobe and refresh your curtains. Like irons, they used to take 2 full minutes to heat up. Now some go from zero to steam in less than 30 seconds and come with accessories to dewrinkle more efficiently. Consumer Reports put three affordable steamers to the test.
Sales of ultra high-definition TVs are up sharply this year. With their great picture quality, it's no wonder. Ultra high-def TVs offer four times the pixels of regular HD TVs, which means four times the detail. The best models Consumer Reports tested offer superior picture quality, and the vast majority are smart TVs with access to Internet content.
Getting a driver's license is a big milestone for teenagers and their families. But along with that is the worry of rocketing insurance premiums.
Consumer Reports' exhaustive study of insurance rates found just how high they go up when you add a teen driver.
Consumer Reports' exhaustive study of insurance rates found just how high they go up when you add a teen driver.
With fall cleanup looming, it's that time of year when people are buying leaf blowers. Consumer Reports has tested and rated more than 60 gas, electric, and battery-powered models.


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All Obituaries Posts
Sister Marita Catherine Leinmiller dies at age 86Posted on August 21st, 2015
The I.H.M. sister taught in Catholic schools in the Philadelphia Archdiocese and served as a pastoral minister in a New Jersey parish for 20 years.
Sister Mary Appolonia Matijasic, I.H.M., dies at 93Posted on August 20th, 2015
Sister Mary taught for 40 years at Immaculata University, as well as in the Archdiocese of Philadelphia, the Diocese of Allentown, and Chile.
Father Stephen White, civil lawyer and parish priest, dies at 62Posted on August 11th, 2015
Ordained in 1986 and known for his "brilliant" mind and ability to weave old songs into his homilies, he had been retired due to health reasons.
Sister Emily Wright, math teacher for 30 years, diesPosted on August 11th, 2015
I.H.M. sister, a teacher for almost 50 years, dies at 95Posted on July 16th, 2015
Sister Catherine Dunleavy entered the Sisters, Servants of the Immaculate Heart of Mary in 1941 and taught in elementary schools until 1990.
Deacon who 'couldn't do enough for the Church' dies at 88Posted on July 10th, 2015
Permanent Deacon James Burns served at St. Eleanor Parish in Collegeville, and did so much that "the Church was his hobby," according to his family.
I.H.M. sister who served for 71 years dies at age 95Posted on July 10th, 2015
Sister Paul Bernard Blankemeyer taught at St. Aloysius Academy in Bryn Mawr and Annunciation School in Philadelphia.
Sister Helene Joseph Kollar, longtime teacher, diesPosted on July 10th, 2015
The Sister Servant of the Immaculate Heart of Mary taught in the Philadelphia Archdiocese and other dioceses. She was 70.
Franciscan sister dies at 84, had cared for babies with AIDSPosted on July 2nd, 2015
Sister Judith O'Neill, O.S.F., taught for over 30 years in various archdiocesan schools. She served in prayer ministry until her death.
Franciscan sister, a teacher and musician, dies at 90Posted on July 2nd, 2015
Sister Frances Will, O.S.F., served in the education ministry with the Sisters of St. Francis of Philadelphia for over 60 years.

subset: commoncrawl


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The Espanola Valley Sundevils and the St. Pius X Sartans were the winners in Saturday's late games of the Class AAAA boys basketball state first round.
The Sundevils topped the visiting 15th seed, Valencia, 66-52, while ninth-seeded St. Pius pulled off an upset over eighth-seeded Kirtland Central, 65-38.
The tournament continues Wednesday with the quarterfinal round. Los Alamos has lost three straight seasons in the state quarterfinals.
The Hilltoppers will take on the Albuquerque Academy Chargers in Wednesday's quarterfinal. That game is scheduled for 8 a.m. at University Arena (The Pit).
In the girls AAAA tournament, Los Alamos will play Espanola Valley Tuesday at 1:15 p.m. That game will also be played in The Pit.
For more information about those games, read Tuesday's Monitor.
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Earl Sweatshirt
News & Features
OF Records
Earl Sweatshirt Hints at Name Change, Doesn't Want to Be "a Joke Forever"
[Image via DiarmuiF] Earl may soon be taking off his sweatshirt for good. The LA-based rapper and former Odd Future member took to Twitter... Read More
Posted 2 months ago by Brendan V
The Dysfunctional Brotherhood of Tyler & Earl
When you announced your engagement, I wondered what happened to the kid that I used to watch chase girls around the monkey bars in elementary school.... Read More
Posted 5 months ago by Yoh
Earl Sweatshirt Finally Finds Himself on "I Don't Like Shit"
Can you imagine the mindset of Nasir following up Illmatic? Wu-Tang after 36 Chambers? Snoop after Doggystyle? It has to be a psychological battle... Read More
Posted 6 months ago by Yoh
Odd Present: OFWGKTA is All Grown Up & Rewriting Music's Rules
I turned the television to Jimmy Fallon, influenced by a Twitter timeline full of excitement for this group that was about to hit the stage. How... Read More
Posted 7 months ago by Yoh


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Nyko Zoom: the Kinect accessory designed for your small living room
A new Kinect accessory announced at E3 could open up Microsoft's motion sensor accessory to thousands of new gamers in the UK when it comes out later in the year.
The Zoom from Nyko is an optical bolt on for the Kinect sensor that promises to increase the range of the device so you can stand considerably closer to the sensor than you currently can.
That's important for UK, European, and Japanese gamers with small living rooms as it means that you are less likely to have to move furniture to get the most out of the revolutionary gadget for the Xbox 360.
Nyko, the company behind the new device, claims that it's around a 40 per cent improvement. That relates to you being able to stand about 3ft closer to Kinect in your lounge.
Pocket-lint tracked down the new accessory to give it a go. In reality it's a very simple idea. There is no moving parts, no electronics, but just two optical lenses that sit over the current camera sensors and then act as a wide angle lens to increase the range of Kinect's cameras.
We played Kinect Adventures, the game that ships with the sensor, and one that requires a large space to play.
With the new accessory we were able to play the game as we would without it, however the big difference was that we were only around 4 ft from the sensor rather than about 6ft.
The gaming experience was identical. We noticed no lag in our movement, and the accessory – in our brief play – didn't appear to affect the gameplay whatsoever.
The company tells us that the new Zoom will be going on sale in the US for $30 in August, and will be due out in the UK shortly afterwards (but before Christmas) depending on how the US launch goes. The price has yet to be decided, but expect it to be £30.
PlayStation Now subscription service comes to the UK: What is it, and how can you get it?
Ubisoft's next Far Cry title goes primal with Stone Age setting, coming 2016
Microsoft HoloLens gets $3,000 price and Project X-Ray mixed reality game revealed
Hanging around with Nathan Drake: Pocket-lint chats to Nolan North about gaming superstardom
- PlayStation Now subscription service comes to the UK: What is it, and how can you get it?
- Ubisoft's next Far Cry title goes primal with Stone Age setting, coming 2016
- Microsoft HoloLens gets $3,000 price and Project X-Ray mixed reality game revealed
- Hanging around with Nathan Drake: Pocket-lint chats to Nolan North about gaming superstardom
- Forza Motorsport 6 review: The Forza is strong with this one
- Can't afford the Xbox One Elite controller? Don't worry, you'll be able to remap your existing controller buttons
- Halo 5 limited edition Xbox One controllers now available: This is what they look like
- Watch first trailer for episode one of Minecraft: Story Mode, coming this month
- PS4 System Software 3.0 Kenshin coming tomorrow, what will you get?
- Project Spark for Xbox One and Windows goes completely free from 5 October
- Which iPad is best for you? iPad mini 2, iPad mini 4, iPad Air, iPad Air 2 or iPad Pro?
- Motorola Moto X Play review: Big-battery beauty
- Best smartphones to look forward to in 2015
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- 21.5-inch iMac now available with Retina 4K display, all 27-inch iMacs get Retina 5K
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- Best smartphones 2015: The best phones available to buy today
- Tesla's autopilot mode: When is it coming and what can it do?
- Canon PowerShot G9 X hands-on: G whiz, 1-inch sensor in slender body impresses


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When he talked, Brandon Marshall said little.
Not that this was important. His cleaned-out locker screamed out his intentions, anyway. And by cleaned out, we're talking down to the Spic-n-Span.
The Broncos' megatalented, controversial receiver left behind not one stitch of clothing. There was not one shoulder-pad strap, not one shoelace, no Sunday game-day program in which he was featured on the cover for the week in which he was forbidden to play.
Marshall was the only Broncos player who not only completely emptied his locker Monday but removed his nameplate.
"Appreciate being here for four years and the opportunity to still play football," Marshall said before heading out.
Marshall took his 327 career catches, his 25 touchdowns, his back-to-back Pro Bowls (he likely will be wearing a Broncos helmet for the final time on Jan. 31 in Miami), his ear-to-ear smile, his belongings, his uncanny knack for stirring trouble and freed himself from Broncos Centre.
It's the second time this year he packed up his locker and left the Dove Valley premises. There was his minicamp walkout in June after a meeting with owner Pat Bowlen, remember? This time, it appears Marshall has left for good, if the Broncos can work out a trade.
As the Broncos try to put another late-season swoon behind them, they will do so without Marshall in their plans. The Broncos will attempt to trade Marshall in March with hopes of getting decent value in return, according to four NFL sources.
Tight end Tony Scheffler, who like Marshall was dismissed from participating in the Broncos' 44-24 loss Sunday to the Kansas City Chiefs, also will be placed on the trading block.
"I thought I played the best I could," said Scheffler, who took a more wistful departure from the Broncos' locker room, as if he wanted to take one last long look around. "If that's not good enough, then I think there are a lot of opportunities elsewhere."
The day after the season's final game always is one of the most melancholy moments in sports. It was especially depressing for the 2009 Broncos, whose farewell team meeting with coach Josh McDaniels and pack-up-the-locker chore came much sooner than expected for a team that started 6-0.
It was a 2-8 finish that brought the Broncos to haul out trash bags filled with belongings before the NFL playoffs start.
"Things didn't turn out the way we wanted this year, but I think we've shown at times how dominant this system can be," Broncos running back LaMont Jordan said. "There are lessons to be learned by everybody. It's also a learning experience for Josh. I know he's a competitor, and I know he's just as disappointed, if not more so, than we are as players. I think because of his drive, we're going to be that much better as a team next year."
A better Broncos in 2010? It starts with McDaniels, who is now officially a second-year head coach.
"He'll form the team he wants and he'll have a little more wisdom of being a head coach," running back Correll Buckhalter said. "I'm pretty sure it's not easy. There's always something."
The final-week decision to discipline Marshall and Scheffler was something. Hours after another historic Broncos' collapse was complete, several veterans talked about how the team has a chance to be special once it matures.
"When you sit back and take a look at yourself, you can't be sensitive to criticism," Jordan said. "Especially when it's coming from your coach. That's what I mean when I say lessons."
Behind closed doors, and sometimes in front of sold-out stadiums, McDaniels has been known to chew out his players and assistants. Such admonishments occasionally caught some Broncos players off guard.
"I do think that the second year there will be a different response, because it's expected," McDaniels said. "I think each player will have an opportunity to handle whatever it may be — coaching, criticism, critique, adversity — better in their own way. And I think also we're going to have a better feel for each player."
Besides, coaching tactics, McDan-iels indicated improvement needs to come through a better draft and addressing the line of scrimmage. While disappointing production from the rookie class was an issue from beginning to end, the biggest difference between the 6-0 and 2-8 Broncos was the play up front.
The Broncos dominated the scrimmage line during their fast start. But when Broncos tailback Knowshon Moreno averages 43.3 yards a game on 2.7 yards a carry in his final four games, while opposing backs Michael Bush and Jamaal Charles combine for 392 yards rushing on 9.1 yards per carry in home losses to Oakland and Kansas City, something's wrong up front.
"If you struggle to run the football, and stop the run, that's a double whammy," McDaniels said. "And we ran into that on a few occasions here in the last half of the season, there's no question about it. That makes everything harder."
As McDaniels and his coaching staff stay back for three weeks of evaluating the current team, the players exited Dove Valley. Some will return. Some have left for good.
"It's a sad ending, but the Broncos under Josh McDaniels will be successful, and we'll be successful very soon," Jordan said. "It's just a matter of us learning the lessons like we're supposed to and how quickly the players in this locker room can buy into the system."
Mike Klis: 303-954-1055 or firstname.lastname@example.com


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They are going ahead with a Justice League movie
View Single Post
June 7 2012, 12:20 PM
Rear Admiral
Re: They are going ahead with a Justice League movie
Christopher wrote:
It's great that these movies feel like parts of a greater universe, that they affect each other and feed into each other. I think there's a nice progression in the past four films -- Fury fills in Tony on the Avengers Initiative, then Coulson splits off to deal with the Asgardian incursion, which brings in Selvig, who gets introduced to the Tesseract; and then we flash back to the story of how the Tesseract came into play, which is also the backstory of Captain America; and then all those threads come together when Loki invades. It's very deftly done.
Right. A JLA movie out of nowhere is absurdly reactionary.
They need a plan as opposed to retroactively sticking their existing movie characters into a movie.
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text:
By Spectrasonics
VST OSX/Win, AU OSX, AAX, RTAS OSX/Win, 32/64-bit support.
Omnisphere 2
Upgrade to Omnisphere 2 from 1.x (Free USPS shipping*)
After many years of development, Spectrasonics™ are thrilled to announce Omnisphere 2. This is the first v2.0 of any Spectrasonics instrument and it's truly a gigantic one! Check out the new feature list and the video introduction by Spectrasonics Founder and Creative Director, Eric Persing.
Vast New Synthesis Possibilities:
Now includes over 12,000 sounds!
New Interface:
Enhanced Browsing Experience:
New Arpeggiator Features:
25 New FX Units:
Flexible New FX Features:
Improvements/Special Features:
- and more!
• 2.4 GHz or higher processor
• 4GB RAM minimum, 8GB or more recommended
• Dual Layer compatible DVD-ROM drive
• 64GB of free hard drive space
Mac Users:
• OSX 10.8 Mountain Lion or higher
• AU, VST 2.4 or higher, RTAS/AAX capable host software
• Audio Unit plugin requires host with support for "Cocoa" based plugins
• Native 64-bit and 32-bit on OSX
Windows Users:
• VST 2.4 or higher, RTAS/AAX capable host software
• Microsoft Windows 7/Vista compatible
• Native 64-bit and 32-bit on Windows
Q: Who qualifies for a FREE Upgrade to Omnisphere 2?
A: New customers who purchase Omnisphere 1.x between October 2014 and May 2015.
Q: What is the upgrade pricing?
A: VIP upgrades are available for $199* to customers who own Omnisphere, Trilian, and Stylus RMX (Standard Licenses, no license transfer/NFR). Standard Upgrade price is $249* for all Omnisphere 1 customers (Standard and Transfer Licenses).
Q: Where can I purchase the UPGRADE to Omnisphere 2.0 when it's available April 30, 2015?
A: You'll be able to purchase the upgrade from ILIO and your favorite dealer, as well as directly from the Spectrasonics website.
Q: Will all my projects saved with Omnisphere 1.x sounds and settings work with Omnisphere 2?
A: Yes!
Q: Will the ILIO EDM Patch collections work with Omnisphere 2?
A: Yes! Upon release of Omnisphere 2, The ILIO EDM patches will have a new file format for Omnisphere 2 which will allow for drag-and-drop installation.
* Sales tax for California and Texas residents not included.


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December 4, 2012
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On July 15, 2015, the Wage and Hour Division of the U.S. Department of Labor (DOL) issued Administrator's Interpretation No. 2015-1, adopting a very expansive interpretation of the definition of employees under the Fair Labor...more
- Administrative Interpretation DOL Employee Definition Employer Liability Issues FLSA Independent Contractors Misclassification Multi-Factor Test Wage and Hour
On September 10, 2014, California Governor Jerry Brown signed into law AB 1522, the Healthy Workplaces, Healthy Families Act of 2014 ("the Act"). The Act grants nearly all California employees the right to at least three...more
- Employee Rights Paid Leave Sick Leave
In a far-reaching decision, the California Second District Court of Appeal held in Cochran v. Schwan's Home Serv., Inc., Cal. Ct. App. No. B247160, (August 12, 2014) that California Labor Code section 2802 requires employers...more
- Bring Your Own Device Cell Phones Reimbursements
Compelled by U.S. Supreme Court precedent advancing arbitration as a method of dispute resolution, the California Supreme Court in Iskanian v. CLS Transportation Los Angeles, LLC (No. S20432, June 23, 2014) held that its...more
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Hello all,
I've been lurking on the NM forum for the last few weeks and am in need of some advice. I'd post this on the Wheel/Tire forum, but honestly I figure you guys are much more relevant advice given that you are all familiar with the trail conditions around here.
I've recently gotten back into riding after moving back to NM from DC (almost 5 years of 60-70 hour weeks will kill you!) and have been mostly riding around the foothills. Typically once or twice a week after work I'll enter bear canyon below Tramway & Manitoba, climb to the wilderness fence and then ride over near the Tram and back. This is a nice quick ride that i can just bomb after work. My fitness level is improving and I'm getting some of my old bike handling skills back, but I'm sure I have a long way to go.
My older hardtail has a set of Mavic Crossmax wheels on it and I've been using Hutchinson Python tires since "back in the day," but I'm a little unhappy with the way the front tire is starting to track when I'm doing higher speed runs back down the canyon to my parking spot. I think my tires are worn out and I'm looking for advice on what i can replace them with that will be appropriate for NM conditions.
My hardtail is pretty light and I'd like to keep it that way, but I'm not a weight freak. I also am not going to do any monster downhill action. I'm looking for a tire that will roll fast, has good traction and will climb well in our conditions. Any suggestions?
Results 1 to 9 of 9
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Dustin Pedroia off the charts - 0 Comments
ANAHEIM, Calif. — At a time when the Red Sox are taking a sledgehammer to their World Series-winning roster, it seems more than ever as though no one is untouchable, the organization having entered such a state of flux after the trade deadline that any player is available in the right deal for the right return.
Dustin Pedroia should be the exception.
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Applesauce Squares
Source: dLife
Delicious squares of applesauce cookie!
1 cup white all purpose flour
0 1/2 cup Oats, rolled, old fashioned
0.3333 cup brown sugar
0 1/2 tsp salt
0 1/2 tsp baking soda
1 tsp low sodium baking powder
1 tsp ground cinnamon
0 1/4 tsp ground cloves
0 1/2 cup Margarine, hard
2 each egg whites
1 tsp vanilla extract
1 cup sweetener (sugar substitute)
0.3333 cup chopped hazelnuts
1 cup Applesauce, unsweetened, with o add Vit C, canned
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Conservatives announce new parental benefits under employment insurance
Kulak earns coveted job on Calgary Flames blue-line to start the season
Scott Disick "feels free" after splitting from Kourtney Kardashian and...
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The snow and cold weather arrived just before Christmas and we are all nestled in for a long winter around here. Some of the lakes are frozen, but I would be watching and waiting a while before venturing out on the ice. Not too many snowmobilers out as yet, we need more snow for trails.
The community wishes to thank all who donated to the Christmas hampers this year and to the special people who volunteer their time to organize, shop, pack, and deliver these hampers. I hope everyone who received a hamper realize how truly blessed we are to have community and volunteers who care.
Here are some brief Township of Georgian Bay notes; the past summer areas of the township had septic Inspections. The Stewart Lake area around MacTier was done and from all reports all premises passed with flying colours.
Also in December 2012, the council has hired MHBC Planning Urban Design and Landscape Architecture to write the Township of Georgian Bay new zoning bylaw. It is anticipated to take one year to prepare the new zoning bylaw.
Here is a "did you know" of the past: back in the 1930's at the present MacTier ball field there was a huge rainstorm (the ball field is built on a bog). The culvert at the far end of the field going under the present railroad crossing got plugged and the field, after the rainstorm, ended up with close to two feet of water.
The local children were swimming on the ball field. This field is close to the level of Lake Stewart on the other side, this makes me wonder why the CPR wants to put an underpass at that location this year. This has to be dug out so that a fire truck, transport, or any large vehicle can get through at a 18-foot clearance.
Do they realize how low they have to go? Why not try the other areas for this, down by the library or an overpass off Muskoka Road?
The MacTier Royal Canadian Legion held a New Year's dance and would like to thank all who attended and to the helpers who assisted that evening.
Here is a bit more nostalgia: the seventh annual Field Day in MacTier was held on Wednesday, Aug. 2, 1939. This was at the above-mentioned ball field, some activities included a softball game with the Doodad Bearcats versus Freeman Bulldogs and a girl's softball contest was played between Parry Sound, MacTier, and Britt. In men's softball, teams were North Bay, Britt, and MacTier. The final game of the day was a hardball game between Parry Sound and MacTier.
There were many other activities taking place and everything wrapped up at the old town hall where Muskoka Station Store now sits with a dance. Mrs. Quinn's Orchestra was the entertainment. The cost to get in was 35-cents. Meals during the day were served at the CPR boarding house.
Hope everyone had a great Christmas and a happy New Year to everyone.
MacTier Curling Club Night mixed League standing as of December 18.
Team Pts
Patenaude 67
Mischler 67
Demkiw 56
Watkinson 53
Rivett 40
Kelly 40
Keall 39
MacGregor 25
Stick Curling Standings as of December 27
Name Pts
Bill 72 1-2
Jamie 53
Earl 45
Dave 44
Marilyn 42 1-2
Dwight 41 1-2
Murray 41
Ed 40
Gail 40
Heidi 39
Brian 34 1-2
Carol 30
Joan 16
Location, ST | website.com
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Up to 69% off Oil Changes and More


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Home » NewHampshire.com » Outdoors » John Harrigan
Courage to say no; pluck of a partridge
I'm pretty sick and tired of the whole Northern Pass controversy. I just wish that the for-greed, not-for-need scheme's side-show barkers would fold up their tents and go home, because
(a) a growing number of New Hampshire citizens know a flim-flam when they see it,
(b) two of the state's southernmost chambers of commerce made drastically ill-advised choices when they came out in favor, and
(c) Northern Pass cannot build on its proposed route because . well, it doesn't own the dirt. In three critical places, the Forest Society or private property owners with conservation easements own the dirt.
On Friday afternoon, approximately 75 people who've been in the fight against this insult to the North Country's landscape got together, just as an excuse to get together, at the Thompson lodge in Stewartstown where Chet Noyes Road intersects Bear Rock Road.
The lodge overlooks the Bear Rock valley, through which Northern Pass proposes to come with its huge towers and huge swaths of cleared land, and smack across other equally knock-your-eyeballs-out scenery. It's worth noting here that in the North Country, scenery and tourism are about all we have left.
This is strictly a get-rich-and-New-Hampshire-be-damned scheme. New Hampshire exports almost as much power as it uses. The power would not go to us anyway. It would go to the lucrative Hartford-New York City markets. Hydro Quebec, after decades of despoiling the Far North, is now desperate to sell its power.
Bob Baker, a lawyer who has a home on Meridan Hill in North Stratford and has done much legal work pro bono (i.e., free) for those opposing Northern Pass, stated flatly that the Nashua Chamber of Commerce has misrepresented (polite term) the findings of a UNH poll by stating that support for Northern Pass is growing. Not true, he said, adding that the UNH pollsters have written the Nashua Chamber to demand that it stop skewing their findings.
The Manchester Chamber of Commerce chose a similar ill-advised path and endorsed Northern Pass on scant or distorted information.
I was chagrined that my alma mater (i.e., the Nashua Telegraph, where I started newspapering, straight out of a lumber yard in 1968) fell for this tripe.
Jane Difley, the Forest Society's head honcho (honcha?), said the Society is fully aware that Northern Pass, which has spent upwards of $40 million on land so far, has "a barn-full of lawyers" ready to go, but so does the Forest Society, which she said would pursue things to the bitter end should NP try to breach conservation easements.
I've written about the road by my front lawn being used as part of the town road links that help make the Ride the Wild's huge circular multi-town ATV route possible. Every now and then I get the querulous question, "My, but don't you get sick of all that ATV traffic going by your house?"
In a word, no. The vast majority of ATVs are not ultra-loud, raw-power machines driven wildly by teens and twentysomethings. They are relatively quiet and involve respectful and law-abiding riders who, fully packed for a multi-day trip, wave and often stop by the roadside to visit. These are the people who are making the cash registers ring.
A week ago, I spoke at New Hampton's Old Home Day, a real treat (hint: I love to speak, especially if it involves good food and music). Because I'm temporarily crippled up and should not drive due to mind-altering drugs, they even sent a car and driver to fetch me and bring me back home afterward.
In my talks (not speeches, ever) I cover a lot of ground, from settlement times to Indian trails to cougars and wolves, but I was mildly kerflummoxed by the almost non-reaction I got when I mentioned the bravery of a drumming partridge.
A hand shot up. "Do you mean ruffed grouse?" Yes. "What's drumming?" It's when a male partridge picks just the right spot to beat its wings very fast to create a drumming sound that carries hither and yon, conveying the message "Hey, cutie, how about a date?"
(Hint: If you've ever been in the woods and heard a sound like someone trying to start up an outboard motor or a lawnmower or chainsaw, that's likely to be a drumming partridge.)
Imagine the courage this takes. This bird, selfless and self-sacrificing, sends the message to prospective mates to perpetuate the species, but in doing so alerts every coyote, fox and fisher cat as to exactly where it is, waiting there like a snack on a toothpick.
Ye gods (guys, thump your chests here), what a Brave Heart performance by this wonderful pedal-to-the-metal, Warp Factor Five bird.
Write to John Harrigan at email@example.com or Box 39, Colebrook, NH 03576)
|NH Angle >> Outdoors
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UAE: Biggest climber in visa index
Click here for the top 10 rankings in the regionOctober 8, 2015 6:09
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MIDEAST STOCKS-Markets to rise on stronger global environment
Abu Dhabi's ADWEA in talks with banks for $350 mln project bond
Emirates hints at no Dubai Airshow orders, pushes decision on A350/787 to next year
UAE minister says plans to boost oil output capacity on track
MIDEAST STOCKS-Saudi, Egypt markets barely move in early trade
Qatar Q2 GDP growth accelerates to 4.8 pct year/year
UAE says reforms will better protect foreign workers
United Arab Bank secures $125 mln three-year loan
MIDEAST STOCKS-Saudi hit by weak oil, commodities; Egypt down modestly
MIDEAST STOCKS-UAE markets narrowly mixed in thin, early trade
As the UAE celebrates its 40th year milestone, we take a look at one of the many networks of the UAE President.
November 30, 2011 3:10 by shafeer
Gulf News quoted the ruler of Umm Al Qaiwain as saying: "I want to be mentioned in history as a fair ruler who tried his best to make his people enjoy the greatest amount of welfare, and that I had dedicated my life to preserve noble values that were followed by our ancestors." Sheikh Rashid, born in 1932, was selected by his father to chair the municipality of Umm al Qaiwain in 1968 shortly after which he was appointed to the head of his father's office. Sheikh Rashid hails from the Al Ali tribe, which is also known as "the nobility of Rabeea Tribe." He came to be the ruler of Umm Al Qaiwain in 1981 and is credited with the rapid economic development of the Emirate – in particular, he is esteemed for his efforts of increasing commercial exchange internationally through land, sea and airports.
Egypt's Christians seek to be heard in election
November 30 2011
The Network of Sheikh Khalifa bin Zayed bin Sultan Al Nahyan
November 30 2011


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a terrible blight on our fine country
- Member for
- 2 years 35 weeks
- Blog
- View recent blog entries
Recent Comments
|4 days 19 hours ago
|Hungarian waffle impresario
please consider making this a tag and tagging anything Maryland related with it, or at least Randy Edsall.
|3 weeks 6 days ago
|Except Ohio State lost two
Except Ohio State lost two quarterbacks and went on to win the national championship and our two PGs got hurt we couldn't make it to the NIT.
|3 weeks 6 days ago
|I hope you are right - this
I hope you are right - this all just feels like Michigan is overreacting to the Tyus Battle situtation. Recuit Winston for 2+ years, make him the clear priority at PG and then he wants to move his OV and it all falls apart?
|4 weeks 5 days ago
|1997 vs. Colorado - I was a
1997 vs. Colorado - I was a freshman. It was a good omen for the year. I, however, remain bitter that the AD gave some students spilt season tickets, so I missed out on Notre Dame the following week. I was happy to still have a ticket to Ohio State that year.
|4 weeks 6 days ago
|I know people see Bleacher
I know people see Bleacher Report and automatically say garbage but some of their writers are excellent - Howard Beck for basketball, for example. Anderson is a big SEC/Alabama guy - he literally wrote a book about Saban - but he is a legit writer. HIs article on Lawrence Phillips this summer was great.
|5 weeks 5 days ago
|I don't think it is damage
I don't think it is damage control or sour grapes - this has been a long standing development, as Ohio State is still looking at a number of WR they like better than Mitchell and might not have room for him. I think they are crazy not to have a commitable offer to Mitchell, but all the better for the good guys.
|10 weeks 16 hours ago
|No - you are thinking of
No - you are thinking of battle
|10 weeks 1 day ago
|Putting Michgan State above
Putting Michgan State above Ohio State makes no sense, even if you agree the Utah game could be tough on the road, first game, new coach/new qb. I mean, Vegas has michigan as a 4/5 point underdog to Utah, 5.5 to state and a 13 point underdog to Ohio State.
|10 weeks 1 day ago
|She didn't even mention Ohio
She didn't even mention Ohio State as a possiblity for Michigan's toughest game! Only Utah or State. I am guessing Ohio State will be a little tougher than the Utes.
|10 weeks 5 days ago
|More Penn State players taken
More Penn State players taken than MSU players is a surprise.
|10 weeks 6 days ago
|It was always bizarre to me
It was always bizarre to me that he was voted tiger of the day almost every time! 0-4? People voted him MVP of the game...
|11 weeks 21 hours ago
|Bacon said the "return"
Bacon said the "return" refers to "the UM family reunifying. tickets sold out, enthusiasm back"
|11 weeks 21 hours ago
|I do not recommend reading
I do not recommend reading scary stories to children at bed time. All night they will have nightmares of the Michigan secondary.
|13 weeks 1 day ago
|Is Texas not an option? Did I
Is Texas not an option? Did I miss something? Is everyone on crazy pills?
|13 weeks 4 days ago
|Borges is the OC at San Diego
Borges is the OC at San Diego state. GERG is the DC there too.
|15 weeks 23 hours ago
|Magnus - I would like to hear
Magnus - I would like to hear you on with Brian and Ace - you guys disagree enough to make for an interesting conversation.
|15 weeks 1 day ago
|Can you clarify (if you know
Can you clarify (if you know or can) - that would mean the following OL would not be here for a fifth year - Kalis, Braden, Bars and Magnuson, who are supposed to be 2 or 3 members of the line this year. It would also leave Dawson, Samuelson and a freshman Bredeson (and if he plays offense a freshman Onwenu) as the only guards on the roster.
|15 weeks 1 day ago
|McKeon shouldn't be on the
McKeon shouldn't be on the list then either - he visited Michigan's campus, not at a satellite camp.
|15 weeks 6 days ago
|Some of the requirements for
Some of the requirements for Director of Internal Communications and Operations for the Head Football Coach
- Travel with football team and head coach.
Translation - don't rent an apartment, live at Schembechler Hall
|17 weeks 4 days ago
|Also, it is Gregg, not Greg.
Also, it is Gregg, not Greg.
|20 weeks 5 days ago
|How depressing would this
How depressing would this season be if Hoke was back for another year? The darkest timeline....
|20 weeks 6 days ago
|More denard on the front page
More denard on the front page please
|20 weeks 6 days ago
|20 weeks 6 days ago
|Denard posbang!
Denard posbang!
|20 weeks 6 days ago
|Is Brian still in a dark room
Is Brian still in a dark room listening to the Smiths? After reading this I think I will join him.
|20 weeks 6 days ago
|21 weeks 1 day ago
|I glanced at the headline and
I glanced at the headline and thought it said Lewis out til mid season. Much happier with the actual headline
|21 weeks 4 days ago
|I just read the thread - they
I just read the thread - they are also greyshirting someone to get up the cap? Not a great look for Urban.
|21 weeks 6 days ago
|Josh Furman was also drafted.
Josh Furman was also drafted.
|22 weeks 4 days ago
|Kentucky guy think Brown
Kentucky guy think Brown might decide as early as today.


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Colorado Springs Science Center Video
|Science Festival
October 3 - 11, 2015
|Science on Tap
Fun Discussions
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Science In
Science on Tap
Monthly Science and Technology Presentations and Discussions
Join the Colorado Springs Science Center for Science on Tap every 2nd Monday of the month at Jack Quinn's in downtown Colorado Springs. A wide variety of fascinating topics are presented by local scientists for informal discussion, and the relaxed atmosphere encourages anyone and everyone to come explore the latest ideas in science and technology. From practical to theoretical, the presentations and group interactions provide a fun and interesting way to gain an understanding of the world around us.
Next Up:
Monday September 14th, 2015 - Genome-Editing of Embryonic Stem Cells
Tom Wolkow, PhD
Professor of Biology, UCCS
CRISPR/Cas is a natural system that bacteria and archaea use to defend themselves against invading, foreign DNAs. Professor Wolkow will talk, from personal research experience, about how scientists are now learning to leverage the CRISPER/Cas system to alter the DNA sequence of stem cells, including embryonic stem cells, in search of patient-specific stem cell therapies. Not only will we examine more closely what this leading-edge research is actually about, but we will also explore the ethical, safety and America's stem cell policy implications of it all.
Tom Wolkow is an Associate Professor of Biology at UCCS. His Bachelor's degree is from Lafayette College (Easton, PA), where he worked in Dr. Shyamal Majumdar's lab using electron microscopy to catalog fungal diversity in local rivers and streams. His PhD is from Purdue University (West Lafayette, IN), where he worked in Dr. John Hamer's lab studying molecular mechanisms of cellular development. As an NIH Post-Doctoral Fellow, he studied genomic stability pathways at Harvard Medical School in Tamar Enoch's lab. At UCCS, he continues to study genomic stability pathways while working to transform K-12 and undergraduate STEM classrooms in light of the AAAS Vision and Change report.
Science on Tap is a free event and reservations are not required; however, you'll need to pay for any drinks and food. Jack Quinn's is located downtown at 21 S. Tejon Street, Colorado Springs, CO, 80903.
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Economy - Most Commented
Where are women in the debt talks?
Jul 19, 2011
Besides House Minority Leader Nancy Pelosi, there are no women in the leadership of the debt ceiling debates. Congresswoman Susan Davis, a Democrat from California, says that should change.
The details of the latest debt ceiling plans
Jul 18, 2011
There are a lot of different debt ceiling plans in progress right now in Washington, but will any get through before the Aug. 2nd deadline?
New nominee for consumer finance protection
Jul 18, 2011
Richard Cordray, former attorney general of Ohio, is the nominee to head the new Consumer Financial Protection Bureau. But is any alternative to Elizabeth Warren, the interim head of the bureau, acceptable to Republicans who oppose the agency?
Richard Cordray new pick for consumer bureau head
Jul 18, 2011
President Obama today will not announce Elizabeth Warren to be his nominee to head the new Consumer Financial Protection Bureau. Former Ohio Attorney General Richard Cordray is expected to get the nomination.
S&P turns up the heat for a U.S. deficit deal
Jul 15, 2011
Standard & Poor's warns it may cut the U.S. credit rating if the debt ceiling is raised, but the impasse over longer-term fiscal issues remains.
The future of the Consumer Financial Protection Bureau
Jul 15, 2011
We take a listen to the congressional hearing on the new Consumer Financial Protection Bureau and a home owner who shares what he hopes the new agency will do for consumers like him.
Congressman Cooper: 'My colleagues are misbehaving'
Jul 15, 2011
Congressman Jim Cooper, a Democrat from Tennessee, urged his fellow lawmakers earlier this week to stop misbehaving and posturing for voters. He says that people need to remember to put their country first.
Wall Street versus Main Street reaction to debt ceiling debate
Jul 15, 2011
Jill Schlesinger, editor-at-large at CBS/MoneyWatch, says people are reacting differently to this week's debt talks, and looks ahead to what could happen should politicians fail to settle the debates.
Debt talks: Are we ready for Plan C?
Jul 15, 2011
President Obama told lawmakers that "it's decision time" for the ongoing debt talks. But is there an actual deal within reach?
Credit agencies heighten warning on U.S. debt
Jul 14, 2011
As politicians quarrel over a deal to raise the debt limit, Moody's joins Standard & Poor's in warning it might cut the U.S. credit rating.


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What an amazing place. The garden was more beautiful than I imagined after reading other reviews. Chuck and Kristy are wonderful. They do not intrude on vacation, but are around if you need them. They provided every kitchen item I could imagine, including glassware, serving pieces, foil,..., and wagons to take the umbrellas, beach towels, coolers, chairs, current magazines, they provide for the beach. The washers and dryers and the grill and hot tub were a bonus. The beach is not crowded in this area. If you are handicapped, the access to the beach is not easy, but worth it. Just be prepared. The sand is like powder, so you sink into it more than other beaches I've visited. It is beautiful. The location is across the street from the beach, and mid way between the bridge and Bean Point. I cannot wait to go back.
- Official Description (provided by the hotel):
- Island Garden Villas is a lush tropical setting for your unforgettable island adventure. Just across the street from the sugary white sands of the Gulf beaches, our villas offer a serene and relaxing retreat. Whether you come for a romantic getaway or a family vacation, Island Garden Villas, with the tranquility of its flagstone courtyard, charming old world fountain and enchanting tropical gardens is the perfect spot. Accommodations include fully equipped kitchens, cozy living areas and luxurious bedrooms. We have everything you will need for the perfect beach vacation including beach chairs, umbrellas, and towels, as well as bikes for exploring the island and a fabulous hot tub for relaxing after a hard day at play. As a family owned and operated establishment, our guests receive the utmost in personal care and attention. Come, escape to paradise. ... more less
- Also Known As:
- Island Garden Villas Hotel Holmes Beach
- Island Garden Villas Anna Maria Island/Holmes Beach, FL


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All Android applications categories
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by: BarbieW | 5.3K
This is a simple pink, black and teal GO SMS Pro theme.
1.This is not a standalone app, you need to download latest GO SMS Pro in order to apply this theme; You can check GO SMS Pro out by searching "GO SMS Pro" in google market
2.To apply the theme within GO SMS Pro after downloading:
Menu->Theme->Installed->Select theme and apply.
Tags: pink&purple polkadots go
from 5.343 reviews


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What's New
Come together for more fun at HIVE!
We've fixed up some minor bugs!
Have feedback? Leave a review or drop us a line at [email protected]
App Description
Group up for more fun at HIVE!
HIVE is a global social platform where you can play mobile games and interact with your gaming communities!
* HIVE is available in English, 한국어, 日本語, 中文简体, or 中文繁體.
- Get social! Send friend requests, messages, and game invitations to users from all over the world to enjoy Com2uS & Gamevil games together!
Game Center
- All your favorite Com2uS & Gamevil games, gathered in one convenient place! Get updates on the hottest new games, and download them all!
- Keep up with special events, share gaming tips, and make friends on the game forums!
Connect with your mobile gaming community!
For questions or customer support, please contact our Customer Support by visiting http://www.withhive.com/help/inquire
App Changes
- September 13, 2013 Initial release
- November 18, 2013 New version 1.1.0
- December 20, 2013 New version 1.2.0
- February 12, 2014 New version 1.2.1
- March 25, 2014 New version 1.2.2
- August 19, 2014 New version 1.3.0
- September 26, 2014 New version 1.3.3
- July 14, 2015 New version 1.3.6


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Welcome to Thunderbird Add-ons.
Add extra features and styles to make Thunderbird your own.Close
Review for Confuscator! by Nibinaear
Rated 3 out of 5 stars
Sorry but what's the use of it?This review is for a previous version of the add-on (0.5.3.1-signed).
To create your own collections, you must have a Mozilla Add-ons account.


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In mybook®: Health
Dowling, Patti C, DDS
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Dental ImplantsA periodontist is a dentist who specializes in the prevention, diagnosis and treatment of periodontal disease and in the placement of dental implants. Periodontists receive extensive training in these areas, including three additional years of education beyond dental school. Periodontists are familiar with the latest techniques for diagnosing and treating periodontal disease. In addition, they can perform cosmetic periodontal procedures to help you achieve the smile you desire. Often, dentists refer their patients to a periodontist when their periodontal disease is advanced. However, you don't need a referral to see a periodontist. In fact, there are occasions when you may choose to go directly to a periodontist or to refer a family member or friend to your own periodontist.
Root Canal TreatmentEndodontic treatment is necessary when the pulp, the soft tissue inside the root canal, becomes inflamed or infected. The inflammation or infection can have a variety of causes: deep decay, repeated dental procedures on the tooth, or a crack or chip in the tooth. In addition, an injury to a tooth may cause pulp damage even if the tooth has no visible chips or cracks. If pulp inflammation or infection is left untreated, it can cause pain or lead to an abscess.
DenturesDental implants are designed to look, feel, and function like your natural teeth. With dental implants, there is no longer the need for messy pastes and creams for your denture. It does not compromise or attach to the adjacent teeth like bridges or other appliances, so it acts like a single unit or tooth.
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Genetic Variants of TCF7L2 Are Associated with Insulin Resistance and Related Metabolic Phenotypes in Taiwanese Adolescents and Caucasian Young Adults
ABSTRACT The effect of TCF7L2 rs7903146 on glucose homeostasis is considered primarily due to impaired insulin secretion in European populations. Because we previously demonstrated that TCF7L2 rs290487 near the 3' end of TCF7L2 was significantly associated with type 2 diabetes (T2D) in Taiwanese subjects, we aimed to investigate potential mechanisms underlying the associations of rs290487 with T2D.
Eighteen single nucleotide polymorphisms (SNPs) were tested for association with glucose/insulin homeostasis as well as other quantitative metabolic phenotypes using the quantitative transmission disequilibrium test in 525 Taiwanese adolescent twin-pairs and siblings. The results were further replicated in 116 nondiabetic normotensive Caucasian young adults.
Among the 18 SNPs, rs290487 C allele was significantly associated with higher 60-, 90-, and 120-min glucose concentrations (P = 0.001, 0.01, and 0.02, respectively); higher 60- and 90-min insulin concentrations (P = 0.01 and 0.01, respectively); and a lower insulin sensitivity index (P = 0.04). No association was found for rs290487 with measures of insulin secretion. The rs290487 C allele was also associated with HOMA-IR (P = 0.005) and insulin sensitivity index (P = 0.01) in Caucasian young adults. Another SNP, rs10749127 C allele located in intron 4, was also associated with features of the metabolic syndrome, including elevated systolic (P = 0.02) and diastolic (P = 2.0 x 10(-4)) blood pressure, triglycerides (P = 7.0 x 10(-4)), and uric acid (P = 0.03). In a meta-analysis, the rs290487 C allele was confirmed to be associated with an increased risk of T2D (odds ratio, 1.11; 95% confidence interval, 1.03-1.19; P = 0.005) across East Asian populations.
These findings support an important role for T2D risk-conferring gene TCF7L2 in insulin resistance in both Taiwanese and Caucasian youth and underscore the emerging role of Wnt signaling in insulin resistance.
- SourceAvailable from: Reza Malekzadeh
- "These findings have implicated altered Wnt signaling in impaired glucose metabolism and diabetes. While the associations between these genetic variants and type 2 diabetes appear as extremely robust, their effects on cellular insulin response are not understood (Liu et al., 2009; Rasmussen-Torvik et al., 2009). In principal, the biological effects imparted by the common polymorphisms are too small to be measurable in artificial cell systems and animal models. "
Article: LRP6 Enhances Glucose Metabolism by Promoting TCF7L2-Dependent Insulin Receptor Expression and IGF Receptor Stabilization in Humans[Show abstract] [Hide abstract]
ABSTRACT: Common genetic variations in Wnt signaling genes have been associated with metabolic syndrome and diabetes by mechanisms that are poorly understood. A rare nonconservative mutation in Wnt coreceptor LRP6 (LRP6(R611C)) has been shown to underlie autosomal dominant early onset coronary artery disease, type 2 diabetes, and metabolic syndrome. We examined the interplay between Wnt and insulin signaling pathways in skeletal muscle and skin fibroblasts of healthy nondiabetic LRP6(R611C) mutation carriers. LRP6 mutation carriers exhibited hyperinsulinemia and reduced insulin sensitivity compared to noncarrier relatives in response to oral glucose ingestion, which correlated with a significant decline in tissue expression of the insulin receptor and insulin signaling activity. Further investigations showed that the LRP6(R611C) mutation diminishes TCF7L2-dependent transcription of the IR while it increases the stability of IGFR and enhances mTORC1 activity. These findings identify the Wnt/LRP6/TCF7L2 axis as a regulator of glucose metabolism and a potential therapeutic target for insulin resistance.Cell metabolism 02/2013; 17(2):197-209. DOI:10.1016/j.cmet.2013.01.009 · 17.57 Impact Factor
- "GLP-1 is not thought to have significant effects on insulin action (the ability of insulin to stimulate glucose uptake and suppress glucose release). Some investigators have suggested that TCF7L2 may adversely affect this parameter (20,21). In this experiment, at identical glucose concentrations, C-peptide concentrations and ISR did not differ significantly by TCF7L2 genotype, although GIR was lower, suggesting an effect on insulin action. "
Article: Diabetes-Associated Common Genetic Variation and Its Association With GLP-1 Concentrations and Response to Exogenous GLP-1[Show abstract] [Hide abstract]
ABSTRACT: The mechanisms by which common genetic variation predisposes to type 2 diabetes remain unclear. The disease-associated variants in TCF7L2 (rs7903146) and WFS1 (rs10010131) have been shown to affect response to exogenous glucagon-like peptide 1 (GLP-1), while variants in KCNQ1 (rs151290, rs2237892, and rs2237895) alter endogenous GLP-1 secretion. We set out to validate these observations using a model of GLP-1-induced insulin secretion. We studied healthy individuals using a hyperglycemic clamp and GLP-1 infusion. In addition, we measured active and total GLP-1 in response to an oral challenge in nondiabetic subjects. After genotyping the relevant single nucleotide polymorphisms, generalized linear regression models and repeated-measures ANCOVA models incorporating potential confounders, such as age and BMI, were used to assess the associations, if any, of response with genotype. These variants did not alter GLP-1 concentrations in response to oral intake. No effects on β-cell responsiveness to hyperglycemia and GLP-1 infusion were apparent. Diabetes-associated variation (T allele at rs7903146) in TCF7L2 may impair the ability of hyperglycemia to suppress glucagon (45 ± 2 vs. 47 ± 2 vs. 60 ± 5 ng/L for CC, CT, and TT, respectively, P = 0.02). In nondiabetic subjects, diabetes-associated genetic variation does not alter GLP-1 concentrations after an oral challenge or its effect on insulin secretion.Diabetes 03/2012; 61(5):1082-9. DOI:10.2337/db11-1732 · 8.10 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Human diabetic neuropathy is multifactorial in etiology, with ischemia as a final common pathology. Although impaired vascular endothelial cell function in diabetic microvascular injury is established, the role of thrombomodulin (TM)-dependent protein C antithrombotic mechanism in the pathogenesis of neuropathy is unclear. This neuropathologic case-control study investigated whether vascular endothelial TM expression is deficient in peripheral nerve microvessels in diabetic neuropathy. Sural nerve biopsies from 7 patients with diabetic neuropathy and 10 with axonal neuropathy without vasculopathy were immunostained with anti-TM and anti-von Willebrand factor (vWF; an endothelial cell marker) antibodies. The proportion of TM-positive microvessels was expressed relative to total vWF-staining vessels, according to vessel caliber and regional distribution within the nerve. In diabetic nerves compared with reference controls, the proportion of TM-positive endoneurial microvessels was 15-fold lower (0.02 vs. 0.30 in diabetic nerves vs. controls, P < 0.004), and the proportion of small-caliber epineurial microvessels was 10-fold lower (0.04 vs. 0.43, P < 0.001). No TM expression was detected at the perineurium in diabetic or control nerves. We demonstrate a substantial reduction of vascular endothelial TM expression throughout human diabetic neuropathy. These findings suggest that an impaired native TM-dependent protein C antithrombotic mechanism may contribute to microvascular ischemia in the pathogenesis of diabetic neuropathy.Diabetes 06/2002; 51(6):1957-63. DOI:10.2337/diabetes.51.6.1957 · 8.10 Impact Factor


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Godfrey Hotel to Intro F&B Concept
Thursday October 3rd, 2013 - 8:53AM
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CHICAGO—The Godfrey Hotel Chicago, slated to open here in February, will debut a food and beverage concept, I|O, a 10,000-sq.-ft. urban roofscape facility that will offer skyline views from its fourth floor location at the hotel.
"While other retractable rooftops require support beams that can obstruct views, I|O's unique design retracts from the top and corner supports, allowing guests to witness Chicago's extraordinary panorama," stated Matthew McCahill, food and beverage director at The Godfrey Hotel.
I|O will offer two full-service bars and lounge seating at the roofscape's two-level fire pit. In addition, I|O will feature a water wall, open-air seating and stingray-inspired cabana canopies. A customizable LED video wall, free WiFi, a green room for talent, and sound and lighting system will accommodate DJs, live music performances and private events.
I|O's menu will feature preparations of Chicago's favorite foods while the beverage program will introduce a new spin on chef-inspired cocktails.
I|O also will serve as a destination in the River North district for private events, offering more than 1,500 sq. ft. of space, plus interior VIP room.
The 16-story Godfrey Hotel Chicago will offer 221 guestrooms when it opens.
Tags: Godfrey Hotel • rooftop • food and beverage • Chicago • Hospitality • Architecure & Interiors • Guest Facing • Construction/Renovation • F+B • Openings •
When Strategic Hotels & Resorts announced in August that it was exploring "strategic alternatives," so to speak, including an outright sale, it left many wondering who had the financial wherewithal to scoop up the luxury hotel company. Many speculated it might be a large private equity company or, perhaps, foreign investors but, in the end, it was, who else, but Blackstone Group LLC that agreed to acquire the Chicago-based REIT.
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Recent flooding has impacted state parks across Texas. Status of Parks — Videos, Photos, News
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ShareLunker No. 211
Caught by David Lee of Longview, TX
March 14, 1995 in Lake Fork
14.16 pounds, length 28 inches, girth 22 inches
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Easily the best-looking Atom-powered hybrid in its price range, the HP Pavilion x2 is still a few tweaks away from being a budget standout.
You can dive into the various subcategories here for detailed suggestions for every need and budget, but on this page, we present the current laptops that are our personal favorites, because of style, power, value, or just because we like them.
With better battery life and performance than the Yoga 3 Pro (not to mention a lower price), the Yoga 3 14 is one of the best hybrid deals around.
While the upcoming 12-inch MacBook has all the buzz, this 13-inch system gets a handful of updates to remain a top choice for combining power and portability.
Along with getting the latest Intel processors, Dell claims the "world's smallest" title for the 15- and 13-inch models with "virtually borderless" displays.
Besides a pair of new gaming laptops, Asus is also getting into the PC Stick field.
LG is getting into the American laptop market with a series of slim ultrabooks.
Lenovo's Y-series gaming laptops get new CPUs, plus gamer-centric accessories.
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Annvix 3.0 Based on Apparmor
About one year after the last major release, the Mandriva-based security distribution Annvix has now replaced RSBAC with Apparmor in version 3.0 and updated its collection of programs.
Kernel version 220.127.116.11 supports multiple processors and up to 64GB RAM. The new version numbers of critical programs are PHP 5.2.5, Glibc 2.6.1, GCC 4.1.2, Apache 2.2.6 and Shorewall 3.4.6. The developers have codenamed the new version Freya.
On its How Does Annvix Compare to Other Distributions page the Canadian project writes that Annvix has been kept as "bloat-free" as possible: for example, the distribution does without an X-Windows server (see the List of packages). Installed packages are not enabled by default: for example, users have to start the SSH daemon manually. According to the project, Annvix is similar to Mandriva in that it uses the security reporting rool Rsec, which is based on Msec by Mandriva. In contrast to the Mandriva tool, Rsec does not initiate changes autonomously.
The Release Notes refer to further new program versions and provide information on the update scripts. The project's download pages have RPM packages with and without source code, and ISOs for network based installation. Annvix supports the i586 and x86_64 platforms.
Issue 180/2015
Buy this issue as a PDF
Dyreza Malware is Back
Powerful man-in-the-middle attack is now targeting online shopping.
Kernel Developer Matthew Garrett Forks the Linux Kernel
Another high-profile coder says the kernel team needs a kinder, gentler culture.
Bugzilla Bug
Bug database has a bug of its own that could allow an intruder to create an unauthorized account.
US Launches New Strategy for Broadband Access
Report focuses federal resources on achieving universal Internet access.
RC4 Finally Gets the Fork
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Mozilla Announces new Firefox API
Future Firefox extensions will be compatible with Chrome.
Weird Security Flaw Affected Intel Chips for 16 Years
Better read this if you bought your computer before 2011
OpenSSH 7.0 Secure Shell Arrives
Users should upgrade to the new version as soon as possible
Qemu Flaw Lets the Guest Escape
Xen project announces a privilege escalation problem for Qemu host systems


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Holy Cross 71, Saint Joseph's 66
PHILADELPHIA (AP)—Tim Clifford and Alex Vander Baan scored 16 points each to lead Holy Cross past Saint Joseph's 71-66 on Tuesday night.
Kyle Cruze added 13 points and Andrew Beinert had 10 for the Crusaders (7-1), who won for the first time in four career meetings against the Hawks.
Pat Calathes scored all 19 of his points in the second half while Tasheed Carr added a career-high 17 and Darrin Govens had 12 for Saint Joseph's (4-3).
Holy Cross built an early 18-point lead and withstood a furious rally by the Hawks, who got within 66-61 with 2:03 remaining. But Saint Joseph's missed five straight shots—two 3-pointers and three field goals—and the Crusaders hit four consecutive free throws for a commanding 70-61 advantage.
The Hawks didn't record their first field goal until Carr hit a 3-pointer with 5:01 left in the first half. During the 14:59 drought, the Hawks missed their first 11 shots and turned the ball over seven times.
Saint Joseph's shot just 3-for-16 in the half and didn't manage one conventional field goal. The Hawks were 3-for-8 on 3-pointers and 12-of-15 from the free throw line as they fell behind 34-21 at halftime.


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Sony Xperia Z3+ available to the US through Amazon for $660
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Verify TCP Port 9100 is unblocked
I've just installed a HP PhotoSmart C4580 'All-in-One' printer on my home wireless network but whenevre I print I get the following message:
"Unable to communicate with the printer. This may be caused by the firewall. If you are using firewall software, verify TCP Port 9100 is unblocked from your PC to the printer 192.168.1.66"
I can ping the printer and if I turn off the McAfee firewall then I can print successfully. Can anyone suggest a solution without having to turn off the firewall.
Re: Verify TCP Port 9100 is unblocked
Hi. I just got a new hp printer and when I try to install it, I am getting the same error message that you did. I was wondering if you ever figured out a solution. Any info you can give me is greatly appreciated.
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Select Local Merchants
Blue Horse LoungeRead MoreCraving finger food? Head to Blue Horse Lounge and chow down on classic pub fare. Blue Horse Lounge provides seasonal outdoor seating — be sure to grab a chair before it's too late. Between the music and the crowds, expect noise levels to reach upper limits at the restaurant. The restaurant fills up on the weekends, so keep that in mind before heading out. Blue Horse Lounge's diners can make use of nearby parking lots. Prices at Blue Horse Lounge typically stay below the $30 mark, so you can afford to bring along a friend or a date.3018 E Service RdCeres, CA US
Skewers Grill & RotisserieRead MoreYour next meal awaits at Skewers Grill & Rotisserie in Modesto. Skewers Grill & Rotisserie is a terrific spot for families to gather with its kid-friendly ambience and menu. Bring your laptop here and tap into the complimentary wifi. Don't stay inside on a beautiful day! Come sit on the patio at Skewers Grill & Rotisserie and order great food. It is not uncommon for Skewers Grill & Rotisserie to feature live tunes or a DJ. For those who enjoy entertainment while dining, Skewers Grill & Rotisserie hosts live DJs. Patrons have the pleasure of listening to live music while they dine. You may be better off finding a table during the week, as weekends at the restaurant tend to be packed. Skewers Grill & Rotisserie also offers delivery and carryout if you're in the mood for the restaurant's cooking but prefer to provide your own ambience. Heading to Skewers Grill & Rotisserie for a tasty meal? Drive on over and park in a matter of seconds.906 J StreetModesto, California US
DevaRead MoreHead to Deva for a tasty cafe bite. Gluten-free, low-fat, and vegan! It's all happening at Deva. Round out your meal with a little tipple — Deva has a terrific drink list, including beer, wine, and more. The perfect place to take the kids, dining out at Deva won't cost you a sitter. Hop online in no time using Deva's free wifi. Warm weather, delectable dishes, and an awesome atmosphere make for a dream night out at Deva. The after-work crowd can fill the place up, so be sure to take advantage of reservations at Deva. If time is of the essence, Deva's take-out option may be a better fit. For the tastes of Deva from the comfort of your next party, the restaurant also offers catering services. null Taste the greatness Deva is serving up with meals around $30. Breakfast, lunch, and dinner are all available at Deva — swing by for your favorite meal.1202 J StModesto, CA US
Vieira's LoungeRead MoreCome to Vieira's Lounge to grab an American classic with a side of fries. For those tired of trendy diets, Vieira's Lounge's lack of low-fat food is sure to make your stomach smile. Pick your poison and toast your evening — drinks are also served here. Don't miss the happy hour food and drink specials, where a great bargain is always in sight. The restaurant's noise level can be somewhat straining on the vocal cords, so intimate get-togethers may be best enjoyed elsewhere. Prepare to face the crowds at Vieira's Lounge during the week — weekends tend to be slower. Don't fuss with street parking. We've got some parking available. Meals at Vieira's Lounge are incredibly tasty and reasonably priced around $30.1700 McHenry AveModesto, CA US
Fat CatRead MoreEase your appetite with delicious bites from Fat Cat in Modesto. Outdoor dining doesn't get much better than the beautiful patio at Fat Cat. Patrons are often seen swaying in their seats thanks to performances from Fat Cat's live musical groups or DJs. For great tunes and lively moves, Fat Cat hosts a DJ and opens up the floor for dancing. Loud is an understatement when it comes to the decibel levels at this restaurant, so it's best to save conversation for another location. The restaurant can get tied up on the weekends, so allow yourself time to wait for a table. With a host of nearby parking options, many choose to drive to dinner. Fat Cat offers parking for all diners, including those who travel by bike.930 11th StModesto, CA US
The BoardroomRead MoreFor an entree that scores high on the taste test, try one of the many options available at The Boardroom in Modesto. Be sure to check out The Boardroom's outdoor seating when the climate is right. Sit back and enjoy the restaurant's live music, or take your table out on the dance floor. Take note that the restaurant can get a bit loud, so vocal cords and eardrums should be in tip-top shape. Those in a rush are better off dining here during the week, as the restaurant draws a crowd during the weekend. Eating on the go? Order some tasty take out from The Boardroom. There is parking close to the restaurant.1528 J StModesto, CA US