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1179 4th Avenue
Harborside, Chula Vista, 91911
Commute to Downtown National City
Some errands can be accomplished on foot.
A few nearby public transportation options.
Flat as a pancake, minimal bike lanes.
Score Details
1179 4th Avenue has a Walk Score of 65 out of 100. This location is Somewhat Walkable so some errands can be accomplished on foot.
1179 4th Avenue is a 27 minute walk from the Blue Line at the Palomar Street Station stop.
This location is in the Harborside neighborhood in Chula Vista. Nearby parks include Lauderbach Park, San Diego Gas and EleCenteric Park and Otay Park.
Explore how far you can travel by car, bus, bike and foot from 1179 4th Avenue.
1179 4th Avenue has some transit which means a few nearby public transportation options. Car sharing is available from RelayRides.
Rail lines:
Blue Line
0.9 mi
Bus lines:
0.2 mi
0.3 mi
0.3 mi
Car shares:
View all Harborside apartments on a map.
Search for homes in Chula Vista or find a Chula Vista real estate agent who knows walkable neighborhoods. Links will open on our partner site Redfin.com.
1179 4th Avenue is in the Harborside neighborhood. Harborside is the 3rd most walkable neighborhood in Chula Vista with a neighborhood Walk Score of 62.


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Muffuletta Spread
- 1 cup pitted Spanish green olives
- 1 cup pitted brine-cured black olives (such as Kalamata)
- 1/4 cup chopped red onion
- 2 tablespoons chopped fresh basil
- 2 tablespoons fresh lemon juice
- 1 tablespoon freshly grated horseradish
- 1 tablespoon chopped garlic
- 1 tablespoon Dijon mustard
- Dash of hot pepper sauce (such as Tabasco)
- Dash of Worcestershire sauce
- 1/2 cup olive oil
- Italian bread slices, toasted
Combine first 10 ingredients in processor and chop coarsely. With processor running, gradually add oil. Transfer mixture to medium bowl. Season to taste with salt and pepper. Cover; refrigerate 1 hour. (Can be made 1 day ahead. Keep refrigerated.) Serve with bread.
Epicurious.com © Condé Nast Digital, Inc. All rights reserved.

subset: commoncrawl


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Hot 1079 Gets 'CAJUN HOT' At The 2015 UL Block Party [VIDEOS + PHOTOS]
Students lined up over an hour before the 2015 UL Block Party began to make sure they got their hands on our 'CAJUN HOT' t-shirts!
Students lined up over an hour before the 2015 UL Block Party began to make sure they got their hands on our 'CAJUN HOT' t-shirts!
It's that time of year again—BACK TO SCHOOL! As always, we are welcoming the students back with perfect Hot 1079 'CAJUN HOT' t-shirt.
The UL-Lafayette Ragin Cajuns are preparing for their season opener on September 5th against Kentucky, but that hasn't stopped the Cajuns from having some fun. The team has invited the student body at UL to take part in a practice later this week.
As UL-Lafayette students return to campus this week, they will be greeted with new buses at Cajun Field this semester.
The University of Louisiana at Lafayette hosted a candlelight vigil Friday night to honor the two young women who died this week in the Grand Theater shooting.
Listen on the air, RadioPup or on-line at www.kpel965.com.
The UL Ragin' Cajuns fans sang the National Anthem prior to one of the games at Lamson Park when it would not be played before the start of the game.
As the UL Ragin Cajuns prepare to take on the Evansville Aces tonight in the historic Blackham Coliseum, a lot of work has gone into preparing the arena.
No matter how cold or severe the weather may be, UL rarely shuts down it's campus—and these memes perfectly describe the struggle for students.
We want to say congratulations to UL Head Coach Mark Hudspeth and his wife, Tyla, on the birth of their second child.


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SYRACUSE, N.Y. (AP) -- Cedric McGowan and Jihad Muhammad each
scored 19 points, James White had 18 and Cincinnati surged past
Syracuse 82-65 on Wednesday night, dealing the Orange a severe blow
to their postseason hopes.
It was the first of three straight home games against conference
foes for the struggling Orange (17-8, 5-6 Big East), who have lost
six of eight and fell behind the Bearcats (17-9, 5-5) in the
conference standings. The victory avenged a 77-58 loss to the
Orange a month ago.
Devan Downey had 16 points and seven assists, and Eric Hicks had
eight points, 11 rebounds and five blocks for the Bearcats.
Eric Devendorf led the Orange with 15 points, Gerry McNamara had
14, Demetris Nichols 13, and Matt Gorman a career-high 10.
Cincinnati scored the first six points of the second half, and
White had four of them as the Bearcats showed they weren't about to
fold after losing a seven-point lead before the break.
White stole the ball from Nichols and scored on a fast-break
layup, then followed that with a two-hand slam dunk to put the
Bearcats up 46-41 less than 2 minutes in.
Two free throws by Hicks put Cincinnati up 57-50 at 12:52, and
after Gorman's three-point play moved the Orange back within four
points, the Bearcats took off.
Cincinnati sealed it with a 15-2 run that left the Carrier Dome
crowd booing the home team.
A layup by Hicks and a follow slam and long jumper by McGowan
got the Bearcats rolling as they easily beat Syracuse's pressing
defense. Muhammad's three-point play off a steal from Nichols
boosted the Cincinnati lead to 74-61 with 6:25 remaining as the
Orange sputtered.
Syracuse scored only two baskets in the final eight minutes.
The Bearcats, led by White's 12 points, held the lead for most
of the first half. But after White's hook in the lane at 14:05,
Devendorf scored seven straight points to tie it at 18-all.
A 3-pointer by Nichols, one of four he made in the period, and a
hook in the lane by Gorman gave the Orange their first lead, 27-24,
as they took advantage of four straight turnovers by the Bearcats
midway through the half.
Muhammad hit a 3 and a follow by Hicks, his only basket before
the break, gave Cincinnati its biggest lead, 38-31, with 3:22 left.
But McNamara and Nichols each hit 3-pointers as the Orange closed
the period with a 10-4 run and took a 41-40 lead into the locker


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Lambeth Wind Orchestra is having another busy year of music-making.
Forthcoming events in 2015:
|Saturday 8th August 2015
|Victoria Embankment Gardens. Victoria Embankment, Westminster WC2N 6PB. 2.30pm - 4.30pm.
|Saturday 5th September 2015
|Ruskin Park Bandstand, SE24 0AA. 3pm – 5pm.
|Saturday 14th November 2015
|Autumn Concert. St Paul's Church, Herne Hill SE24 9LY. 7.30pm


text:
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In a somewhat surprising 9th Circuit ruling (en banc, or in front of the entire set of judges), the court ruled that the 4th Amendment does apply at the border, that agents do need to recognize there's an expectation of privacy, and cannot do a search without reason.
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All Jackets - MensSave on Men's All Jackets at Proboardshop.com! Great selection of street gear at unbelievably low prices. Proboardshop has been selling All Jackets and outdoor gear for over 30 years and we're proud of it.
Please refine here
- Category: "Snowboard Jackets"
- Brand: Nike
- Color: Black
Nike 700 Down Print Snowboard Jacket
Size: Medium, Large, X-LargeReg: $270.00 On Sale: $188.95
Nike Aeroloft Kampai Snowboard Jacket 2014
Size: X-LargeReg: $450.00 On Sale: $292.95
Nike SB Assistant Coaches Snowboard Jacket
Size: Small, Medium, Large, X-Large
Our Price: $160.00
Nike SB Hazed Snowboard Jacket
Size: Medium, Large, X-LargeReg: $220.00 On Sale: $153.95


text:
I Am a Dreamer
Personal Stories, Advice, and Support 7,251 People
Be happy and smile because it happenedand you can't really be upset about anything there's nothing to really be upset about and be happy and always keep the faith never give up, never quit, always feel the energy and the magic of the earth, and if anyone ever stands in your way between you and your goal push them...
debonaireash 18-21, M 1 Apr 29
If your dreams don't scare you They're not bigenough The first step to getting what you want is having the courage to get rid of what you don't
charlene0712 41-45, F 4 Responses 5 May 7
Waking from the best day of my life behind myeyes where I am the artist of a perfect picture. To be smacked in the face by the harsh reality that it was only just a dream
chasetheweirdo8 13-15, M 1 Response 10 Mar 29
One of my biggest flaws: dreamingand hoping for the best.
1998zodiac 16-17, M 1 Response 6 1 day ago
I really am. I'm a nocturnal dreamer.I'm a day dreamer. I have dreams, obviously. I do all sorts of dreaming. I'm almost always in my head coming up with new creative things.
MaybeAnotherDay 16-17, F 1 Response 3 2 days ago
The heaviest battle with oneself... Who will win?
mariuspanazan 26-30, M 2 Responses 0 3 days ago
These worn out boots onthat worn out street, these dancing eyes and these wandering feet. This great big world and this me, so small, the noises so loud and the buildings so tall. There's so little time and so much to see, I just hope that it's you that sees it with me. -Tyler Knott Gregson- (at...
Sweetchic5 36-40, F 1 Response 6 Nov 2, 2014
One day this will be me...I hope
trew5432 13-15, M 2 Responses 6 Jul 7
Transgendergirl01 13-15, M 1 Response 0 May 21
Living On PossibilitiesAll of my life I have maintained my strength of spirit by dreaming. The possibilities that lay before me have been my guiding star through the darkest of dark times. Now that I am older I feel a mounting urgency to more avidly pursue what I desire. Life will not go on forever...
Epiphany68 41-45, F 4 Responses 6 Jun 29, 2012
I mean yea :P dreaming is nice it's like a veryvisible imagination. Or you can consider it a movie that you watch while you sleep about your imagination of a life :P anything you want can happen in a dream. It's like a personal perfect scenario :) Idk I like dreaming
Raptax231 22-25, M 5 Dec 7, 2014
I'm in love with my straight friend... He told me he'd go gay for me, not that he meant it for real but I wish he did mean it... He called me baby which made me feel amazing I just wish something would happen where he would be bi or gay and date me, plus he's sexy af and smells amazing all the time haha
NightWriter216 18-21, M 3 Responses 7 5 days ago
Dreams were put in our heartsfor a Devine reason. It's our duty to fulfill our dreams no matter how tough the road may get!
CDoza 26-30, M 0 Aug 5
I wake up but am I really awake,I look up but what can I really see, the limitations by which I was burdened, are they really a burden me, or perhaps I am insane still holding on to the illusion of sanity, what is beauty, is it really in eye of the beholder, or Is the beholder just lying so he can hold...
RebelLynx 18-21, M 6 Jul 1, 2014
DISHWASHER~ To see or use a dishwasher in yourdream suggests that you need to resolve past issues and old problems in order to make a clean start for yourself. Alternatively, the dream means that you are moving ahead and looking toward the future. You have got to be kidding me?! Dirty forks and spoons sneaking into my...
HotMessExpress101 31-35, F 2 Responses 5 Feb 23
I dream a lot of stuffthat will never happen
shikas 13-15, F 1 Response 0 Apr 7
I could never picture myself not dreaming,even if it means going through the nightmares. One day I'll be that trauma nurse, even if it means having to abandon my full ride in Washington to move back to florida and start all over
jenneruz 26-30, F 4 Jan 7, 2014
how boring would not the world be without ourimagination? the clouds would only be lumps of water, not dragons, castles or floating mountains! The sea would only be a deep and dark place with fishes, not a mermaids home with huge underwater castles! And the holes in the trees, The flowers and the forest would not be a...
Sarah248 22-25, F 4 Responses 8 Mar 1, 2014
Good morning star shine,the earth says " hello"...
Deszyy 22-25, F 0 May 4
I do this guys and you should to ..anything is possible remember that
trew5432 13-15, M 1 Response 4 Apr 11
I have often dreamed of buying a large piece ofproperty. I would turn into an escape resort. A place where all would be welcome. Straight/bi/gay/trans. Traditional/poly. Clothing optional. I'd even have family weeks/weekends where they can enjoy being out among other people. Sort of a small town all on its own. What do...
charlene0712 41-45, F 1 Apr 12
And my dreams, as of late,have all been of you. Daydreams are the most vivid. Walking by your side. Reaching out to grab your hand. Finding you in the middle of a crowd. Running to you, embracing you, holding you. Everywhere I am you are. And while distance tells us otherwise, I feel you close to...
NewShoes12 26-30, M 1 Jun 23
Some may say I'm a dreamer But I'm not the onlyone I hope some day you'll join us And the world can be as one
steviehunt 18-21, M 2 Responses 6 May 13
The Dreamer and the Dream Evenafter all these years of dreaming I am still dumbfounded by the intricacy and originality of the "props" that lie scattered across the dream stage. One of my dreams, for instance, featured a carefully crafted letter from a past love which included a map of the Pacific Coast near...
KellyKerri 18-21, F 3 Responses 4 Feb 26, 2014
Idk why but my mind is locked on findingsomeone to love but idk why I never had to have Someone to make me happy now I feel like I want someone special ...why do I feel this way
trew5432 13-15, M 1 Response 5 Mar 31
I just wish things would go well between us.Every time there's tension, it makes me think more of what I want and don't want in a relationship.I sadly realized something; I'm not in love because if I were, I wouldn't be so infatuated by other people, thinking grass is greener on the other side. I wouldn't feel so lustful...
Laez 22-25, F 2 Responses 1 May 22
Ever dreamt you've done a task,but then wake up and have to do it again!
Deszyy 22-25, F 1 Response 2 Apr 28
Deszyy 22-25, F 1 Response 1 Apr 28
To live a creative life,you must lose the fear of being wrong.
mstv1112 18-21, F 2 Responses 5 Mar 25
Take me higher Open the sky up Start a fireI believe Even if it's just a dream --an old favorite song:: dreamer, bethany dillon
dreamcatchingstars 31-35, F 1 Aug 20
Sleep is where I find comfort in my cursed life.Dreams give me hope in death.
HarlotCurse 22-25, M 3 May 16
Edgar Allan Poe is pretty much the only poet Ilike. <3 Nevermore
SocietyIsFucked 18-21, F 9 Responses 21 Dec 10, 2014
I like being a dreamerbecause dreamers can do anything. there's really no limit to the imagination of a dreamer, dreamers have this soul, this force, these emotions inside of them, that really make them special and different than anybody else on the planet even two dreamers in the same room can be...
debonaireash 18-21, M 3 Apr 29
I used to have a habit of dissociatingwhen I was younger to be able to deal with life. The older I get, the more it goes away. With my pregnancy, the dissociation finally come to a good stand-still. I wanted to live the life I had and didn't want to be somewhere else or something else. I do have dreams, but they...
FreewritingFreyja 26-30, F 1 Response 5 Dec 3, 2014
I dream about becoming successful one day,by helping others. I dream about making a difference in the world. I dream of writing a book. I dream of living somewhere hot, near a beach or something. I dream of becoming a psychologist, or a therapist. Maybe a criminal psychologist. I dream of becoming a good fighter. I...
fastlife22 18-21, F 1 Response 4 Mar 7, 2014
Identity halts spiritual growth.You must nullify your ego and balance the trinity. Unite as one, mind, body and soul.
HarlotCurse 22-25, M 2 May 1
Every day, A thought will cross my foreverconstant and actively Creative mind. Those thoughts or ideas, quickly forming in my head together to make a small 'bubble' quickly turning into a plan or a Dream. Usually I take things from my surroundings and I'll take small pieces, piecing them together slowly over time to...
Dream girls are exactly what they are...dreams. Only this time mine has awake and has been put on earth; but not for me to have, but for someone else to claim. #LifeSucks
VGod888 22-25, M 7 May 14, 2014
Man on the Train: Hey,are you a dreamer? The Dreamer: Yeah. Man on the Train: Haven't seen too many of you around lately. Things have been tough lately for dreamers. They say dreaming is dead, no one does it anymore. It's not dead it's just that it's been forgotten, removed from our language. Nobody...
secretlyslytherin 18-21, F 3 Responses 4 Jan 18, 2014
iloveblackfire2222 13-15, M 0 Jun 28
Okay so out of curiosity how many of you wouldwatch a movie where a 15 year old girl went through bullying at school, abuse at home, only to be depressed and suicidal, on medication to "cope" with feeling so lost, having to transfer to a different school because the bullying got so out of control, then getting involved in...
I had a weird dream where I was someone I knowand had blue and green disks in my wrist and could see through my skin and my mom and boyfriend (well my friend's mom and boyfriend) where telling me "not to worry, it's fine" and I was freaking out and crying then I woke up ( the person I was is named PHIL fyi) the dream really...
Zoellaphan 16-17, F 1 Apr 30
I was the kind of kidwho grew up thinking I'd change the world and I'll make everyone live happy. What happened to my childhood? I guess I got to a stage in life where I had to face reality, where all my dreams were killed and all my hopes were buried. The child inside of me, tries every now and...
FadingStar17 18-21, F 2 Responses 7 Nov 4, 2014
Hello Stranger! Can you tell uswhere you've been? More importantly, however did you come to be here? Though a Stranger you can rest here for a while. But save your energy, your journey here is far from over. Come the sunrise we'll descend though judgment valley. And weigh your worth before her majesty, The...
HarlotCurse 22-25, M 1 Jul 27
I Am A DreamerFor as long as i can remember. The quite kid sitting alone in the garden that was me. I was the odd one and still i am i do as my heart wills, not very exciting things mostly stupid and meaningless thing that were my treasures. The joy of climbing a Tree and sitting on a high...
lazyangel 22-25, M 8 Responses 4 Feb 18, 2011


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Michael Koretzky
|Michael Koretzky
Michael Koretzky is an American journalist, editor and writer.
Koretzky attended the University of Florida in the early 1980s, where he worked at the Independent Florida Alligator, UF's student-run newspaper. After several attempts he was selected to become the editor in chief in 1987.[1]
He has worked at several publications including the Sun-Sentinel in Florida and XS.[2] While working at the Sentinel, covering the city of Boynton Beach, he started his own publication, Ice Magazine. He also was the managing editor of a jazz magazine, Jazziz.[3]
Koretzky also organized a First Amendment Free Food Festival[4] on the campus of Florida Atlantic University on Constitution Day in 2006. He received a grant from College Media Advisers and the South Florida Chapter of the Society of Professional Journalists to host the event.[citation needed]
Koretzky was the adviser for Florida Atlantic University's student-run newspaper, the University Press for almost 12 years. In May of 2010 Koretzky was fired from the University Press[5][6]
- ^ Alligator Alumni
- ^ That's Why They Called It XS
- ^ The Jazziz Idea
- ^ To Observe the First Amendment
- ^ Travis, Scott (28 May 2010). "FAU adviser fired, but still advising". Sun-Sentinel. Retrieved 5 May 2015.
- ^ Sheperd, Gail (19 May 2010). "FAU Fires Longtime University Press Adviser Michael Koretzky". New Times Broward-Palm Beach. Retrieved 5 May 2015.


text:
For example:
@interface Fraction: NSObject {
When wouldn't
NSObject be used and is
NSObject the ultimate parent class for all other classes?
Please feel free to correct me on any wrong terminology used.
For example:
When wouldn't
Please feel free to correct me on any wrong terminology used.
If I was writing a subclass of NSView, I would write:
because my class is inheriting from NSView. Classes in Objective-C inherit from only a single parent class. As you work your way up the chain from NSView (to its parent class, NSResponder), you would find that it eventually inherits from NSObject.
I'm not sure about the second part of your question. I think all classes in Apple's Cocoa Frameworks eventually inherit from NSObject, but don't quote me on that. There's no reason, in Objective-C, why there couldn't be other root objects (otherwise Objective-C would only be used on Apple systems). However, in Cocoa, NSObject is the root.
In any Cocoa app, if you examine the runtime class tree, you will find five root classes: NSObject, Object, NSProxy, NSMessageBuilder, and NSZombie.
Most ordinary objects in your app will be descended from NSObject. Object is the original root class from the early days of Objective-C, and it was superseded by NSObject when NeXT was developing the Enterprise Objects Framework.
NSMessageBuilder is used by the runtime for message forwarding. NSProxy is used by the distributed objects implementation to deal with marshaling messages to send to objects in other processes or even on other hosts. NSZombie is a class that's used for debugging memory leaks.
Cocoa has two root classes: NSObject and NSProxy.
NSObject is the root class of almost all Cocoa objects.
NSProxy is an abstract superclass defining an API for objects that act as stand-ins for other objects or for objects that don't exist yet, and is the root class for classes like NSDistantObject.
Both classes implement the NSObject protocol.
It is also possible to write your own Objective C classes that do not have a root class, but you would probably never do that, and you would not be able to use it with Cocoa for much of anything unless you also implemented the NSObject protocol, and even then it would be of dubious use.


text:
It's not yet 7am and I'm awake. The gym is beckoning, if nothing more than the allure of delicious distraction. Distraction. Distraction from writing and the incessant anxiety plaguing me. Yes, even at such an early hour. My imagination is working hard conjuring up a mixed pot of alternatives, suggesting that my anxiety will dissolve at the gym at about the same time when my muscles begin to beg for mercy.
I blame my imagination for this chunky slew of anxiety that's riddling my creative prospects. It's my imagination who constantly toys with the idea of early rising for writing. Dipping the idea into a pool of glorious advantage, despite personal history pointing to the contrary. Honestly, early rising has never really been my style. I'm more of the just one more chapter, oh shit, it's 2am kind of woman.
Including writing in my daily routine is often fallible as I'm not particularly fond of regimentation. Some days I look over at my moleskin sitting lonely and expectant on my bedside drawer, sending taunting whispers my way and I desire nothing more than to pick her up, throw her violently across the room. Our shared relationship flirting in-between both raging and wonderful. For every page I spinelessly tear out at her seams, is a thread of words she has aggressively tore out of me. Together, we engage in a heartbreaking romance with one another. Typically though, all hate is forgotten, resentment instantly dissolved by my needy reliance. Accurately put, my desperate need to declutter my twisted insides across blank pages.
I love writing simply for the sake of writing. Writing prevents me from tunneling into the depths of overwhelm when emotionally weighted thoughts fire at me with serrated edges. Take fear for instance, fear can take a stubborn hold over me, emanating strident cockiness. Despite the myriad occasions fear and I have acquainted ourselves with each other, I'm yet to understand fear. Therefore, I cannot tolerate its presence. Often, fear refuses to take leave, further assuring me that its only intention is to be a soul crushing, arrogant asshole.
Fear flings toxins my way hopeful of breaking me down. Each thought conjured up by fear is coated in it's own illness inducing pesticide, possessing only a tiny cautionary label among its contents. I'm not always successful in fighting fear, nor am I always able to comprehend why fear chooses to niggle away at me. I devise my own theories, although most of them are futile without the confirmation of certainty, and you just can't replay these frightening scenes over and over in your mind without turning into a crazed lunatic.
And so I write, hopeful that writing will provide sufficient mental clarity. I write. I write for release. I write. My pen in hand, I write until my fingers beg for respite. I write myself free.


text:
StartUpHire is the place to find Sales jobs in and near Ewing. Review the list of Sales Ewing career opportunities to the left. These Sales jobs represent some of the most rewarding careers available.
You can refine your job search for Sales career opportunities in Ewing by adding a job title, company name, or keyword to the search box above … or click the "Advanced Search" link for more options.
Don't see the employment opportunity you're looking for? Check back soon for more Sales jobs in Ewing, or sign up for an email alert (link below) to receive periodic updates on new Sales jobs in Ewing, NJ.
Demand for Sales Professionals in Ewing, NJ
Mt. Laurel, New Jersey Job Description All Coverd, a division of Konica Minolta Business Solutions, is seeking an Area Sales Manager to join our team. Responsibilities: - Attract, hire, train, develop, motivate & manage IT Services Consultants, and lead them to achieve all quota9/8/2015 Mt. Laurel, NJ Save This Job
More information about this job: : ModSpace is filling their Fall class of Inside Sales Associates in our Berwyn, PA North American headquarters. This is an ideal opportunity for professionals with 1-3 years of work experience to join a mid-sized North American company in an9/3/2015 Berwyn, PA Save This Job
ID 2014-1213 # of Openings 1 Job Locations US-PA-Exton Posted Date 7/2/2015 Category Sales More information about this job: Overview: iPipeline is a leading provider of cloud-based software solutions for the life insurance industry. Through our SaaS solutions, we accelerate8/29/2015 Exton, PA Save This Job
Location : Eatontown NJ US 07724 Job Type : Full Time Shift/Hours : First Shift (Day) Career Level : Experienced (Non-Manager) Education : Bachelor's Degree Category : Sales/Retail/Business Development Job Description : At Yorktel we don?t make video, we make video work. We8/10/2015 Eatontown, NJ Save This Job
At Greenlight Technologies, we?re in the process of building a new revenue generation machine by using the latest methods, practices and tools to improve our lead generation process. We?re searching for an Inside Sales Representative responsible for all areas of lead generation8/9/2015 Flemington, NJ Save This Job
Fairfield, New Jersey Job Description All Covered , IT services from Konica Minolta, is focused on enabling the success of small and medium-sized businesses through the effective use and management of technology. The company is the US industry leader in the provision of IT8/9/2015 Fairfield, NJ Save This Job
Job Description Reporting to the VP of Sales, the Sales Director developing and maintaining their assigned prospect list of retailers. The Sales Director will be responsible for seeking out new customers, maintaining relationships with current customers, and managing theirMount Laurel, NJ Save This Job
More information about this job: Overview: Billtrust is a company that leverages leading technology and a commitment to service to support one of the strongest client lists in business. Respected brands like Kraft Foods, CDW, Toshiba, and Stanley Black & Decker rely on us to9/8/2015 Hamilton, NJ Save This Job
HELLO Sidecar is seeking an experienced Director of Inside Sales who likes to motivate teams, generate leads, close deals, and mentor up-and-coming talent. We are looking for a sales leader who can pour even more fuel on what has been an exciting five years of growth for9/7/2015 Philadelphia, PA Save This Job
Responsible for meeting and exceeding the company's annual revenue and sales quota for assigned territory. Identifies, develops, and retains new business relationships via teleconferencing and Internet communications. Develops sales opportunities through prospecting, cold calling9/7/2015 Mountain Lakes, NJ Save This Job
Spine Specialist-Sales Location:Field-Multiple Job Code:DBSSNY0930 Description The responsibility of the Spine Specialist-Sales Representative is to effectively market Globus Medical products within the guidelines of the company Quality Policy and utilizing a consultative8/16/2015 Audubon, PA Save This Job
Location:Audubon, PA Job Code:STMJL0814 Description Sales Trainer- will be responsible for the training of Globus sales representatives and in-house personnel. The three main areas of focus will be on selling skills (using Globus? EPIC program), product knowledge (system8/16/2015 Audubon, PA Save This Job
Location:Audubon, PA Job Code:ATSJL0515 Description Advanced Technology Sales Specialist - The Advanced Technology Sales Specialist is responsible for the training and education of Globus Medical sales reps on select products, primarily ones related to lateral surgery. They8/16/2015 Audubon, PA Save This Job
Location: Multiple, USA NIKSUN is the recognized worldwide leader in making the Unknown Known, by using next generation technology that revolutionizes the way networks and services are secured, protected and managed. The company develops and deploys a complete range of8/11/2015 Princeton, NJ Save This Job
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HELLO Sidecar is seeking a Sales Manager who likes to hunt for opportunities, pitch innovative technology, nurture relationships, and close deals. We are looking for someone to add to our talented team who can pour even more fuel on what has been an exciting five years of growth9/29/2015 Philadelphia, PA Save This Job
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Parsippany, New Jersey, United States Sales 1207 DESCRIPTION Job Summary: Decision Resources Group is seeking an experienced, dynamic Key Account Director to develop new business, manage and upsell syndicated market research within top and mid-tier global pharmaceutical,9/28/2015 Parsippany, NJ Save This Job
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text:
European Journal of Plant Pathology
, Volume 135, Issue 4, pp 831-843
First online:
Natural variation of Medicago truncatula resistance to Aphanomyces euteiches
- Naceur DjébaliAffiliated withCentre of Biotechnology of Borj CedriaLaboratory of Molecular Physiology of Plants, Centre of Biotechnology of Borj Cedria Email author
- , Souha AribiAffiliated withCentre of Biotechnology of Borj Cedria
- , Wael TaamalliAffiliated withCentre of Biotechnology of Borj Cedria
- , Soumaya ArraouadiAffiliated withCentre of Biotechnology of Borj Cedria
- , Mohamed Elarbi AouaniAffiliated withCentre of Biotechnology of Borj Cedria
- , Mounawer BadriAffiliated withCentre of Biotechnology of Borj Cedria
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We analysed the resistance variation in 14 natural populations of Medicago truncatula from Tunisia to Aphanomyces euteiches infection. The reaction of M. truncatula lines to A. euteiches infection varied from susceptibility to full resistance. Of the overall level of phenotypic variation, 65.4 % was found to occur within populations. Principal component analysis showed a high spread of lines belonging to the same population, indicating no clear structure in the Tunisian M. truncatula populations and supporting the hypothesis of gene flow among populations. Likewise, there was no association between local resistance composition and the geographical distances between populations, ruling out isolation by distance as an explanation. Furthermore, significant correlations were observed between quantitative traits and ecological factors consistent with the local adaptation hypothesis. A cluster analysis of the populations showed the presence of three groups. The first group comprised the populations originating from the centre of the country, containing the main resistant lines. The second group included the populations collected in the south and the mountain region of Thala and contained the main partially resistant lines. The third group comprised the populations sampled from the north regions and saline soils and included the main susceptible lines. Overall, we found that the natural M. truncatula lines were more likely to be susceptible (71.3 %) than resistant (28.7 %) to A. euteiches attack. Nevertheless, many resistant lines exhibiting new reaction patterns to A. euteiches attack were identified in the natural populations and these can be used for the identification of potentially new resistance genes.
KeywordsBiodiversity Model legume Natural populations Oomycete pathogen Tunisia
- Title
- Natural variation of Medicago truncatula resistance to Aphanomyces euteiches
- Journal
European Journal of Plant Pathology
Volume 135, Issue 4 , pp 831-843
- Cover Date
- 2013-04
- 10.1007/s10658-012-0127-x
- Print ISSN
- 0929-1873
- Online ISSN
- 1573-8469
- Publisher
- Springer Netherlands
- Additional Links
- Topics
- Keywords
- Biodiversity
- Model legume
- Natural populations
- Oomycete pathogen
- Tunisia
- Industry Sectors
- Authors
- Naceur Djébali (1) (2)
- Souha Aribi (1)
- Wael Taamalli (1)
- Soumaya Arraouadi (1)
- Mohamed Elarbi Aouani (1)
- Mounawer Badri (1)
- Author Affiliations
- 1. Centre of Biotechnology of Borj Cedria, B. P. 901, Hammam-Lif, 2050, Tunisia
- 2. Laboratory of Molecular Physiology of Plants, Centre of Biotechnology of Borj Cedria, B. P. 901, Hammam-Lif, 2050, Tunisia


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Amvets Thrift Store
Love this thrift store. Always walk out with a sweet gem. So far- I've scored beautiful dresses, 2 ringer Ts (a natty bo and a pinball champ) and 70s...more
City Mattress
Terrific customer service. Good prices. Very fair terms with regards to returns. When we began our mattress search, we were looking for a particular...more
Second Chic
Second Chic is one of my favorite places on Earth. I've been coming to the Elmwood location since the first month they opened, and I have absolutely loved...more
Hobby Lobby
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Spoiled Rotten
ahhh! Kate L. you beat me to the punch to review Spoiled Rotten. At the suggestion of someone that I saw in Spot coffee this afternoon, she recommended...more
Amherst Paw Park
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beach Dhaegs playground bocci? " well this is really wilkeson point. It's a great place to walk your dog, play fetch with them in the water. Plan is once...more
Buckhorn Island State Park
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Soma Cura
I came to Soma Cura with my mom, to try to chair yoga class. The facility is very calming, clean and the staff was welcoming. The chair yoga class was...more
Allen Street Poutine Company
So many choices.... Pulled Pork, Philly Cheese Steak, Montreal Smoked Meat, Buffalo Chicken, Pierogi, Four Cheese...... and those are just a few of the...more
Shango New Orleans Bistro / Wine Bar
I've been here for dinner twice and both experiences have been fantastic! We made reservations and were seated promptly. I just noticed their most recent...more
Kentucky Greg's Hickory Pit
Fast, friendly, hot, delicious, cheaper than most BBQ joints. You'll seat yourself. Be greeted quickly. Served promptly. So far so good, right? Then there's...more
El Ranchito Mexican Restaurant
Molcajete Molcajete Molcajete Say it three times and it can be yours. In a word VOLCAN PLATE Served in a cast iron mini tureen shaped like a Bull. Your...more
Sophia's Restaurant
Put this one on your "must experience" list. GREAT little hole in the wall that always seems busy. Be aware of the hours - and realize that as well as the...more


text:
'07 Authors Insider Tips
by Louisa Burton
Formatting Your Manuscript
Scams / Choosing an Agent
Pitching Your Novel...
From The Call to Published...
Hard Business
From Greg Herren
Who Is Telling This Story?
Its Work, Not A Hobby
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Creating Characters...
Description, Action & Dialogue
Fucking on Paper
Ten No-Nos of Erotic Fiction
Climactic Moments: First Draft
Critique Groups
Revising Your Erotic Story
Finding the Perfect Markets...
Just Submit Already
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Two Girls Kissing
With Amie M. Evans
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Coming Up with Story Ideas
Attend a Writers Conference
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The Perfect Fuck
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The Kingmaker
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The Price of Beauty
The G.O.P.
All Worked Up About Hate
Real Men
Pondering Porn
With Ann Regentin
Good Sex: A Physics Lesson
Meet Frankenstein
Thoughts on the Orgasm Gap
The Very Bloody Marys
The Doomsday Erection
Online Threesome Porn
Mississippi Sissy
A correspondent typed to me a couple of weeks ago, "Hello in Mississippi!" and then remarked how much fun the word was to type. It is also a fun word to say, especially if (unlike many of the natives) you pronounce all four syllables. For an arresting title of his new memoir, Kevin Sessums has paired it with another evocative word to make the tongue-twister, Mississippi Sissy (St. Martins Press), emphasizing the two themes in the book. Sessums grew up in Mississippi in the 1960s, and remembers and relates much of the local color of a distinctive place and time. He also grew up from an early age knowing he was different; before he knew what homosexuals were, he knew he was girlish and liked wearing girls clothes. There were inevitable conflicts in the conservative atmosphere of his little town of Forest, made worse by his own personal tragedies and losses. There is little trace of self-pity here, though. Sessums has a flair for colorful reporting, and uses thoughtful prose to tell his own story of self-understanding, while gently refraining from condemnation of even the darker characters in the book. He admits that the dialogue he reports has to be his own invention, as best as his memory allows. "I was not carrying around a recording device when growing up in Mississippi. But what I did have, even then, was my writers ear. I listened. Thats what most sissies do when we are children: We sit apart and listen."
He could listen to his parents in his earliest years only. His father was everything a good old macho boy could be, a basketball coach who was a loving bully to his family. "You girl," Kevin would goad the father into saying. "You goddamn girl." Among the few times Kevin made his father happy was when his mother had to report that Kevin had been caught with a tomboy neighbor, as the mother says, "playing doctor or whatever in one of those old Baptist softball dugouts behind her house." It was play that the girl had instigated. The mother had told Kevin not to worry about the revelation to his father: "Everything considered, hell probably be proud of you." And so it is: "My father scowled at me before breaking out in exaggerated laughter, Way to go, Kevinator! Maybe theres hope for you yet!" After that, the parents huddle in affection, and Sessums remembers: "Punishment I could have dealt with, but I wasnt expecting to get laughed at and then completely ignored. I realized in that moment I was on neither of their teams. They would always be on one and I would be on another." Kevin was much closer to his mother, who encouraged his cross dressing as something "right cute" when he was little. His aunt Vena Mae objected during a dress-making session, when Kevin was not yet four, "Hes not right nothin. And yall arent right in the head for letting him get his way and encouraging him like this. He has to learn to live in this world and this world dont abide boys like that." The mothers reply is, "Hush up, Aunt Veence. I say let him get all this out of his system while hes young. Hell grow out of it." The father reacts with violence when he finds out about the dress, and probably the family violence would have escalated if he had not died in a car crash when Kevin was seven.
Kevins mother was only to live one year thereafter, succumbing to cancer. It was she who shared a playful camaraderie with the boy, not only encouraging dressing up but also making no objection (as did other family members) when Kevin chose to imitate Arlene Francis, a panelist on the game show "Whats My Line", complete with a blindfold mask: "... it was black and velvet and had pearls all around it just like Arlenes did," only his was imaginary. Aunt Vena Mae cannot get a response from him, and his grandmother, who raised him after his parents deaths, explains, "He dont see you, Vena Mae. Hes got his highfalutin mask on. Call him Arlene and you might get an answer out of him." His mother had shared private jokes with him, and a love of words and of language and literature. One word in particular she wanted to make sure Kevin appreciated, because she felt that she herself had always lived her life as if taking dictation from someone else. "Write it down," she tells him, and he writes down "S-I-S-S-Y", since it was what his father called him and she knew others would, too. "Now, whenever anybody calls you that again you remember how pretty that looks on there. Look at the muscles those Ss have. Look at the arms on that Y. Look at the backbone that lone I has. What posture. What presence. See how proud that I is to stand there in front of you." It was a lesson he did not forget.
Along with a peculiar upbringing, Sessums grew up in a peculiar place and time, and his descriptions of how he came to understand racial matters are poignant. He remembers a gathering of the family menfolk: "A few of the men were in that one-foot-on-a-fender stance that I always saw my uncles take when talking about deer hunting, Goldwaters loss, or all these outside Commie agitators who seemed continuously to be invading our state through my childhood." Aunt Vena Mae, after such agitators were killed, said, "If you ask me - we were discussing this in my womens sixty and over Sunday-school class - those civil rights boys were just looking for trouble coming down here like that where they dont belong. Got what they deserved. This is a sign from God that they should mind their own business." When Sidney Portier won an Oscar, Kevin is curious about how it made the family domestic help feel: "Did you watch the Oscars last night, Matty? Can you believe a nigger won Best Actor?" Matty is dismayed by the word and shows it, and Kevin says, "Niggers an ugly word?"; he had little idea that it was anything but just another noun. "Child, its dugliest," replies Matty, "Jesus never say nigger in dBible. God made us colored folk in his own image too, you know. So if we a nigger, God a nigger, too." He remembers only two teachers who shed tears over Kennedys assassination, and one of them tried to change things for her students. "Some of your parents will tell you bad things about the civil rights movement," she instructs. "But the civil rights movement is not bad. It is how we choose to react to it that can be bad. Dont be bad, children. Mississippi is already full of enough badness." She didnt know that an uncle of Sessums, informed of Robert Kennedys assassination (after that of President Kennedy and of Martin Luther King), roused himself to say, "Were gettin em all. Them Yankees may have whupped us back yonder all them years ago, but we showin em now."
The ugliness is on a par with the scenes of young Kevin being sexually abused by the fundamentalist minister the family admired, or by a stranger in a theater. Kevin left Forest for the big city of Jackson, where he did have a girlfriend and the requisite pregnancy scare, but where he also came to terms with his homosexuality and was unrepentant about it. During college, he worked in the local theater group, which got him associated with a local literary lion, Frank Hains, a newspaper editor and theater booster. Hains was Kevins introduction to Eudora Welty, and included here are Sessumss recollections of the cerebral cocktail-party chatter in which Miss Welty would happily join, as well as his becoming her designated driver for a trip home. The book ends with the ritual gay-bashing murder of Hains; it was Sessums who discovered the body. Sessums was not long for Mississippi; he lives far away now, in New York City, where he has been a contributor and contributing editor to many magazines. Harrowing and funny, his memoir represents a literate coming to terms by a kid, and an author, who, in multiple ways, simply did not fit in.
Rob Hardy
Copyright 1996 and on, Erotica Readers Association, Inc.
'07 Book Reviews
A for Amour / B for Bondage
Review by Ashley Lister
Best Women's Erotica '07
Review by Ashley Lister
The Butcher, The Baker...
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C is for Coeds
Review by Ashley Lister
Cream: The Best of ERWA
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Cream: The Best of ERWA
Perceptions by Cervo
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Review by Ashley Lister
F is for Fetish
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Got a Minute?
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He's on Top
Review by Ashley Lister
Love on the Dark Side
Review by Angelika Devlyn
Lust: ...Fantasies for Women
Review by Ashley Lister
The Mammoth Book Vol 6
Review by Lisabet Sarai
Naughty Spanking Stories
Review by Ashley Lister
Quickies 1
Review by Angelika Devlyn
She's on Top
Review by Ashley Lister
Sixteen of the Best
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Amorous Woman
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The Boss
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Burning Bright
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Call Me By Your Name
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Dark Designs
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Equal Opportunities
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Gothic Blue
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The Lords of Satyr: Nicholas
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Love Song of the Dominatrix
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The Silver Collar
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Tiffany Twisted
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Top of Her Game
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Whalebone Strict
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Wife Swap
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Wings of Madness
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Gay Erotica
Historical Obsessions
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Homosex: 60 Years of Gay...
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Mammoth Book of New Gay...
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Lesbian Erotica
Iridescence:...Lesbian Erotica
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Sex Guides
The Path of Service
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Secrets of Porn Star Sex
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Touch Me There
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Concertina: An Erotic Memoir...
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Daddy's Girl
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Entangled Lives
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Impotence: A Cultural History
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I, Goldstein: My Screwed...
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Insatiable: ...Porn Star
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Letters of a Portuguese Nun
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Ron Jeremy
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Virgin: The Untouched...
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Review by Rob Hardy


text:
Jacksonville beats Lipscomb 88-72
NASHVILLE, Tenn. (AP)—Lehmon Colbert scored 20 points and Ben Smith added 19 as top-seeded Jacksonville rolled to an 88-72 victory over Lipscomb in the semifinals of the Atlantic Sun Conference tournament on Friday night.
The victory sends the Dolphins (18-12) into the championship game against second-seeded East Tennessee State, which defeated Belmont in Friday's other semifinal game.
Lipscomb (17-14) had its nine-game winning streak snapped.
Jacksonville built a 38-24 halftime lead, and extended it to 68-38 with 12:10 to play. Lipscomb pulled within 12 points twice in the final 6 minutes of the game, but it wasn't enough.
All five Dolphins starters finished in double figures, as Marcus Allen and Ayron Hardy added 12 each and Travis Cohn had 11.
Josh Slater led Lipscomb with 17 points.
The Dolphins made 10 of 20 3-pointers en route to victory.


text:
May is Mental Health Awareness Month! This is a great time to highlight the importance of mental wellness and school-based mental health services to children's positive learning and development. Here NASP members can get ideas and resources for promoting children's mental health awareness here.
Mental health services provided in schools should be appropriate to the learning environment and support the mission and purpose of schools; those that are not risk being ineffective or even counterproductive. School psychologists play an essential role in the provision of quality, evidence-based services. We have specialized training in child development, mental health, learning, and school systems. Our unique expertise lies in how these elements interact to shape children's behavior, learning, and overall adjustment.
Get students talking about mental health! NASP is an official partner in Creating Community Solutions and the National Institute for Civil Discourse's Text, Talk, Act program to help raise awareness about mental health among young people. We encourage you to bring Text, Talk, Act to your school. Simply gather your students in small groups and text START to 89800.
NASP is a partner in the Child Mind Institute's 2015 Speak Up for Kids campaign, a free nationwide public awareness campaign designed to protect and promote children's mental health. Speak Up for Kids 2015 features the Change Maker Awards and a new Children's Mental Health Report. The Change Maker Awards honor trailblazers, organizations, and local heroes who give voice to children's mental health. The Children's Mental Health Report will be an annual data-driven summary of key information about children's mental health to illustrate needed reforms.
NASP is also a partner organization for the I Care By campaign, a joint project with the Institute on Disability at the University of New Hampshire which focuses on supporting children and youth with serious emotional and behavioral challenges. The campaign provides participants with specific positive actions to take that have been proven to be successful in supporting youth with behavioral challenges, along with ways to share these actions and encourage others to do the same. Visit the website to take action steps and to access the resources, videos, and information about the award-winning documentary film, Who Cares About Kelsey.
President's Remarks
NASP President Stephen E. Brock, addresses the relationship between mental health and student success, and the need to provide the nation's children and youth with access to high quality school-based mental health services.
NASP 2015 Convention — Keynote Address
Keynote speaker the Honorable Patrick J. Kennedy, discusses why mental health is critical to the health and wellbeing of all Americans, public policy imperatives, and his own journey toward mental health and recovery.
National Association of School Psychologists, 4340 East West Highway, Suite 402, Bethesda, MD 20814
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text:
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Wingtip Clothiers offers all the tools a man needs to create an elegant and refined workday wardrobe. The Gilt-produced line features slim-fitting dress shirts, tailored trousers, silk ties and knit bowties, and other versatile basics to help you hit the office in style. Feel like going a bit more bold with your workwear? Throw on our red marled wool sportcoat and a paisley pocket square. With fresh, crisp looks as well as playful patterns and colors, Wingtip Clothiers will have you dressing both refined and dandily in no time.
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The newest batch of seasonal essentials are here, from cozy cashmere to built-to-last boots
Classic iterations of the most elegant shoe out there by Bruno Magli, Cole Haan, and more


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April 18, 2013 - Industry News
A coalition of U.S. and Canadian trucking interests are close to releasing a best-practices manual for fatigue management.
Tags: J.B. Hunt, ATRI, Con-Way, Fatigue management, Transport Canada, Canadian Trucking Alliance, Challenger Motor Freight, FMCSA, Drivers
We offer e-newsletters that deliver targeted news and information for the entire fleet industry.
The expert, Mark Betner from CITGO, will answer your questions
The expert, Rence Oliphant from Hendrickson, will answer your questions
Relay Bypass Kit Monitors Amperage Draw
Set of Tools Cleans Male Pins on Terminals
SecureFuel Provides Transparent Fuel Payments
McLeod Offers 'Branded' Driver App for Fleets


text:
Michigan's Dennis Norfleet pulls away from Air Force's Wes Cobb during a kickoff return last season.
- Filed Under
The shift to a power running game left Michigan's tailback roster with a glaring outlier: Dennis Norfleet.
The Detroit King grad may be the fastest player on the Wolverines but, at 5-feet-7 and 169 pounds, he also was one of the smallest.
So moving to slot receiver made the most sense for him. ...


text:
Astragalus-based Chinese herbs and platinum-based chemotherapy for advanced non-small-cell lung cancer: meta-analysis of randomized trials. J Clin Oncol
ABSTRACT Systemic treatments for advanced non-small-cell lung cancer have low efficacy and high toxicity. Some Chinese herbal medicines have been reported to increase chemotherapy efficacy and reduce toxicity. In particular, Astragalus has been shown to have immunologic benefits by stimulating macrophage and natural killer cell activity and inhibiting T-helper cell type 2 cytokines. Many published studies have assessed the use of Astragalus and other Chinese herbal medicines in combination with chemotherapy. We sought to evaluate evidence from randomized trials that Astragalus-based Chinese herbal medicine combined with platinum-based chemotherapy (versus platinum-based chemotherapy alone) improves survival, increases tumor response, improves performance status, or reduces chemotherapy toxicity.
We searched CBM, MEDLINE, TCMLARS, EMBASE, Cochrane Library, and CCRCT databases for studies in any language. We grouped studies using the same herbal combinations for random-effects meta-analysis.
Of 1,305 potentially relevant publications, 34 randomized studies representing 2,815 patients met inclusion criteria. Twelve studies (n = 940 patients) reported reduced risk of death at 12 months (risk ratio [RR] = 0.67; 95% CI, 0.52 to 0.87). Thirty studies (n = 2,472) reported improved tumor response data (RR = 1.34; 95% CI, 1.24 to 1.46). In subgroup analyses, Jin Fu Kang in two studies (n = 221 patients) reduced risk of death at 24 months (RR = 0.58; 95% CI, 0.49 to 0.68) and in three studies (n = 411) increased tumor response (RR = 1.76; 95% CI, 1.23 to 2.53). Ai Di injection (four studies; n = 257) stabilized or improved Karnofsky performance status (RR = 1.28; 95% CI, 1.12 to 1.46).
Astragalus-based Chinese herbal medicine may increase effectiveness of platinum-based chemotherapy when combined with chemotherapy. These results require confirmation with rigorously controlled trials.
Full-textDOI: · Available from: Michael Mcculloch, Sep 29, 2015
- SourceAvailable from: Shiguo Zhu
- "However, the high toxicity is a common problem. Natural medicines have been reported to reduce side effects and improve the efficacy of chemotherapy in NSCLC patients (McCulloch et al., 2006; Cassileth et al., 2009; Lee et al., 2013b). Trichosanthes kirilowii Maxim (TKM), a member of the Cucurbitaceae family, is an annual or perennial climbing herb and is widely distributed in China, Korea, Japan, Vietnam, and Laos. "
Article: Trichosanthes kirilowii Fruits Inhibit Non-Small Cell Lung Cancer Cell Growth Through Mitotic Cell-Cycle Arrest[Show abstract] [Hide abstract]
ABSTRACT: Lung cancer is the leading cause of cancer-related death worldwide. Non-small cell lung cancer (NSCLC) accounts for 80% of lung cancer cases and the reported overall 5-year survival rate is less than 5%. Natural medicines have attracted much attention due to their lower toxicity and fewer side effects. Trichosanthes kirilowii Maxim (TKM) fruits are commonly used in cancer treatment in combination with other Chinese medicinal herbs. However, little is known about their biological functions and mechanisms in NSCLC cells. In this study, we investigated the efficacy of TKM fruits in NSCLC cells using cell proliferation, invasion, migration, and anchorage independent assays and a Xenograft NSCLC tumor model, and explored the possible biological mechanism by flow cytometric analysis, cDNA microarray and real-time PCR. Results showed that TKM fruits significantly suppressed NSCLC cell proliferation, migration, invasion, tumorigenicity and tumor growth, and significantly extended the survival time of NSCLC-bearing mice. Flow cytometric analysis showed that TKM fruits significantly induced G2-M arrest, necrosis and apoptosis in NSCLC cells. cDNA microarray analysis revealed that TKM fruits regulated the differential expression of 544 genes, and the differential expression of selected genes was also confirmed. Gene ontology (GO) analysis showed that 18 of first 20 biological processes were involved in cell cycle and mitosis. These results indicate that TKM fruits have certain inhibitory effect on NSCLC cells through cell-cycle and mitosis arrest, and suggest that TKM fruits may be an important resource for developing new antitumor drugs, and a potent natural product for treating patients with NSCLC.The American Journal of Chinese Medicine 03/2015; 43(02):1-16. DOI:10.1142/S0192415X15500238 · 2.76 Impact Factor
[Show abstract] [Hide abstract]
- "The combination of osthole and cisplatin, one of the most active chemotherapeutic agents in lung cancer treatment, resulted in greater efficacy in growth inhibition and apoptosis induction [61]. Meta-analysis of randomized trials showed that Astragalus-based Chinese herbal medicine may increase the effectiveness of platinum-based chemotherapy when combined with chemotherapy [62]. A clinical study showed that the combination of Chinese drugs and conventional chemotherapy in NSCLC patients can enhance short-term therapeutic efficacy in the treatment of NSCLC and prolong patients' median survival time, but it did not find any evident impact on median time to progression [63]. "
ABSTRACT: Lung cancer is a disease with high morbidity and mortality rates. As a result, it is often associated with a significant amount of suffering and a general decrease in the quality of life. Herbal medicines are recognized as an attractive approach to lung cancer therapy with little side effects and are a major source of new drugs. The aim of this work was to review the medicinal plants and other living organisms with antitumor potential against lung cancer. The assays were conducted with animals and humans, and Lewis lung carcinoma was the most used experimental model. China, Japan, South Korea, and Ethiopia were the countries that most published studies of species with antitumor activity. Of the 38 plants evaluated, 27 demonstrated antitumor activity. In addition, six other living organisms were cited for antitumor activity against lung cancer. Mechanisms of action, combination with chemotherapeutic drugs, and new technologies to increase activity and reduce the toxicity of the treatment are discussed. This review was based on the NAPRALERT databank, Web of Science, and Chemical Abstracts. This work shows that natural products from plants continue to be a rich source of herbal medicines or biologically active compounds against cancer.Evidence-based Complementary and Alternative Medicine 07/2014; 2014(5):604152. DOI:10.1155/2014/604152 · 1.88 Impact Factor
- "These differences in patient reaction to QYHJ treatment require investigation; there may be effective and ineffective populations for QYHJ treatment, therefore, a method to distinguish them must be identified. TCM is regarded as a multi-target therapy through immune alteration, tumor microenvironment transforming, oncogenes or tumor suppressor gene regulation, and is comparable to target therapy in modern medicine (17,18). Previous studies have identified that not all patients benefit from target therapies since patients have their own effective population according to their distinctive predictors. "
Article: High expression of erythropoietin-producing hepatoma cell line-B2 (EphB2) predicts the efficiency of the Qingyihuaji formula treatment in pancreatic cancer CFPAC-1 cells through the EphrinB1-EphB2 pathway[Show abstract] [Hide abstract]
ABSTRACT: Our previous study demonstrated that inhibition of erythropoietin-producing hepatoma cell line-B2 (EphB2) expression resulted in the promotion of cancer growth, with EphB2 acting as a tumor suppressor in pancreatic cancer. Qingyihuaji formula (QYHJ), a traditional Chinese medicine, acts as an independent protective factor for pancreatic cancer patient survival and different patients have shown various responses to QYHJ treatment. In the current study, the different effects on tumor growth inhibition following QYHJ treatment in cells with different levels of EphB2 expression were investigated to reveal the mechanism. A subcutaneously transplanted tumor model using cancer cells with different levels of EphB2 expression were established in vivo and received a four-week QYHJ intervention. Tumor weight inhibitory rate and tumor volume deflation were evaluated. The cell cycle and apoptosis were analyzed by flow cytometry, and reverse transcription polymerase chain reaction and western blot analysis were used to assess mRNA and protein levels. The results showed that the tumor weight inhibitory rate was 31.40, 31.33 and 18.36% in CFPAC-1, CFPAC-1 control RNAi and CFPAC-1 EphB2 RNAi cells following QYHJ treatment, respectively. A statistically significant difference was identified in CFPAC-1 (P<0.05) and CFPAC-1 control RNAi (P<0.01) cells. In addition, a statistically significant increase was identified in the G0/G1 phase population (P<0.05) and a statistically significant decrease was identified in the S phase population (P<0.05) in CFPAC-1 and CFPAC-1 control RNAi cells; however, no significant difference was identified in the CFPAC-1 EphB2 RNAi cells following QYHJ treatment. QYHJ upregulated the mRNA and protein level of Eph receptor-interacting B1 (EphrinB1) in the cells that were expressing different levels of EphB2, however, QYHJ did not regulate EphB2 expression. In CFPAC-1 and CFPAC-1 control RNAi cells, the QYHJ treatment resulted in a statistically significant decrease in cyclin-dependent kinase 6 (CDK6) mRNA (P<0.05) and protein (P<0.05) levels. The high expression of EphB2 predicted the superior response rate to the QYHJ treatment through a mechanism of inhibiting the cell cycle by an EphrinB1-EphB2-induced CDK6 decrease in CFPAC-1 cells. Therefore, EphB2 acts as a predictive factor for QYHJ treatment in pancreatic cancer CFPAC-1 cells.Oncology letters 07/2014; 8(1):17-24. DOI:10.3892/ol.2014.2134 · 1.55 Impact Factor


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Spiral Manufacturing Co., Inc. offers a complete line of metal air ducts and supplies for commerc... Read More
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When you need dependable pre-cast concrete forms, turn to Helser Industries. We make steel forms ... Read More
4. Macadam Aluminum & Bronze Co
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At Macadam Aluminum & Bronze Co. we have offered custom bronze plaques and memorials as well as c... Read More
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Welcome to Bridger Steel. We are a custom metal roofing and siding manufacturer serving the Un... Read More
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Welcome to Rustic Metal USA! - A division of Bridger Steel We are a custom metal roofing and s... Read More
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Metalcraft Industries provides the metal fabrication needs of Ocala, FL and surrounding area busi... Read More
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Minnesota Grinding Inc. has provided precision grinding to customers in the greater Minneapolis-S... Read More
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In 1974, Martin Marty Rosenthal founded M & G Industries as an Indent Container Facilitating ... Read More


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Tequesta, FL, USA < change city >
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Evan Nine Wedding DJ and...
Port St Lucie, Florida 34953, USA
DJs, Officiants
2 ratings, 3 reviews, 3 weddings
Well when we hired EVan, we knew that from the start we would jhave a great time....
Evan Nine Entertainment
South Florida
The Treasure Coast
Florida 34953, USA
DJs, Officiants
2 ratings, 2 reviews, 3 weddings
When we hired Evan, we knew from the start that he was just totally amazing. He d...
Traxx Entertainment
Hutchinson Island, FL, United States
2 ratings, 1 review, 2 weddings
They are fantastic!!! Very personable, friendly, and just great people. Add tha...
Academy DJs
Jupiter, FL 33469, USA
DJs, Bands/Live Entertainment
1 rating, 1 review, 1 wedding
Very professional. Played a good mix of music based on the crowd. Very organized.
Marcia Mitchell Music Inc
5407 N. Haverhill Road, #341
West Palm Beach, FL 33407, U.S.
561-963-5056 or 877-FLA-BAND
Bands/Live Entertainment, DJs
1 rating, 1 review, 1 wedding
De La Creme totally rocked the house from the start of the reception until the ve...
Skip Kelly
West Palm Beach, FL, USA
1 rating, 1 review, 1 wedding
Skip was great... i wasn't the "typical" bride with my request and he was happy t...
Marc Evans
Palm Beach Gardens, FL, USA
1 rating, 1 review, 1 wedding
best DJ ever!
Picture It Perfect
Port St. Lucie, FL, USA
1 rating, 1 review, 1 wedding
Djs Ryan and Paul ROCKED our wedding!!!! The dancefloor was packed from the first...
Boogie Brent
West Palm Beach, FL, USA
1 rating, 1 review, 1 wedding
TREMENDOUS! Everyone was up dancing and raved about him afterward.
Kenny Mondo Productions
4047 Okeechobee Blvd. #112
West Palm Beach, FL, United States
1 rating, 1 review, 1 wedding
actually told Roy at the end of the night... "Can you please suck... just a litt...


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Mobile Marketing Archives - Page 3 of 6 - Bruce Clay, Inc. BlogJuly 15, 2014
8 Common Mobile Website Pitfalls to Avoid for SEO
With mobile Internet usage at an all-time high, Google has been cracking down on websites with poor mobile experience. Mobile web design and user experience must be addressed as part of any effective online strategy.
The way a site handles traffic from mobile devices can directly effect that business's presence in search results. Just this month, Google announced it was adding a disclaimer beneath mobile search results that redirect smartphone users from the page they click on in the SERP to that site's home page. From Google's perspective, this disclaimer improves its mobile experience; meanwhile webmasters should be concerned if their mobile websites are ill-equipped to handle the growing number of mobile queries. The pressure is on for websites to provide a user-friendly mobile experience as the number of mobile queries surpassed desktop queries this year.
Read more of 8 Common Mobile Website Pitfalls to Avoid for SEO.
June 26, 2014
A Cheat Sheet for Mobile Design: Responsive Design, Dynamic Serving and Mobile Sites
We've all heard the statistics: 2014 is the year when more people access the Internet on a smartphone than on a computer or laptop. Mobile design is the future. You don't want your site left behind, but how exactly do you program for this increasingly mobile Internet? There are three main options, each with its own benefits and drawbacks.
- Option 1: Responsive Design
- Option 2: Dynamic Serving
- Option 3: A Mobile Site
In this post, I'll break down your mobile-readiness options, giving you the pros and cons of each to help you choose the best path forward for your website. Read more of A Cheat Sheet for Mobile Design: Responsive Design, Dynamic Serving and Mobile Sites.
June 11, 2014
SMX Liveblog: What Advanced SEOs Should Be Doing about Mobile SEO
In this SMX session, discover why mobile really matters, how to build a mobile strategy and what makes mobile search so different from desktop search. This session's speakers include Cindy Krum, Michael Martin, Maile Ohye, and Jim Yu. Kicking of this session on mobile SEO is Maile Ohye, Google's Senior Developer Programs Engineer.
Ohye stresses the importance of enhancing the user experience with mobile search results that open directly within an app. However, it requires deep links within the app and mapping in the sitemap. But asking for app downloads isn't the best approach right off the bat, unless they are relationship-ready customers. Improving the app experience is much like Web SEO, says Ohye. You need good content, an enticing search appearance, and a process for building an effective mobile strategy.
Read more of SMX Liveblog: What Advanced SEOs Should Be Doing about Mobile SEO
May 21, 2014
SEO Newsletter: The Survival Guide to SEO Edition
Coming to you straight from the trenches of Bruce Clay, Inc., it's the survival guide edition of the SEO Newsletter. Our feature article exposes which ranking factors change most frequently so you can stay alert. Then get expert survival tips from our SEO manager on how to stay ahead of the game no matter what SEO bombs Google may throw your way.
With Google's search algorithms changing on a daily basis, content strategist Kristi Kellogg advises Internet marketers to adopt a proactive rather than reactive approach to SEO while SEO Manager Mindy Weinstein shares three key search marketing survival tips.
Read more of SEO Newsletter: The Survival Guide to SEO Edition.
April 30, 2014
The #1 Thing You Can Do to Improve Mobile UX: Image Optimization
Or: So You've Got Responsive Design, Now What?
Having a responsive design is the Google-recommended way to deliver content on mobile devices. While other mobile formats are acceptable to Google as well, Google prefers one over the others. So, while the benefits of responsive design are clear, but what happens when responsive web design isn't good enough? An issue complicating mobile UX for many responsive sites: load time and image heavy sites.
Web developer Trilibis recently released a survey on the web performance of sites utilizing responsive web design and found that 69 percent of those sites did not have an acceptable load time. Perhaps we overlooked user experience and took for granted performance on mobile devices. We thought maybe the relatively fast load times on our desktop sites would translate to responsive design. Our site is content-rich and relevant to user queries. So, what gives?
The single-most contributing factor to slow load times on responsive design mobile sites is images, says the Tribilis survey. Big, fat images.
Read more of The #1 Thing You Can Do to Improve Mobile UX: Image Optimization.
March 12, 2014
#SMX Liveblog: Capturing the Mobile Paid Lead #23C
Moderator Greg Sterling drops a kernel of new info: if consumers have a negative map experience they'll make that negative association with the brand. It's important to make sure your brand's data is right on maps and mobile.
Three presentations by three speakers at SMX West 2014 cover the growing use of mobile apps, how to best leverage a branded app and how to optimize an ad campaign for mobile devices.
Read more of SMX Liveblog: Capturing the Mobile Paid Lead.
#SMX Liveblog: App Store Optimization & SEO for Mobile Apps #22C
If you have a mobile app, this panel covers opportunities to reach new users through mobile app SEO and App Store optimization. App Store Optimization (ASO) is different than SEO because app stores are different. ASO also includes: Top Charts, icons, screenshots, ratings, reviews, etc. Like SEO, the best ASO is a full, well-rounded marketing strategy.
Apps are eating mobile. The percentage of time spent on mobile apps while on mobile: 80%
"For the average app, search actually makes up the vast majority of installs." —Google Play. 50% of daily active users (DAUs) search for apps weekly. There are 6 million unique phrases searched monthly in Google Play App Store. These figures were shared at the last Google I/O conference.
Read more of SMX Liveblog: App Store Optimization & SEO for Mobile Apps.
March 11, 2014
#SMX Liveblog: The Coming Paradigm Shift In Mobile Marketing (#ms2)
Mobile devices like smartphones and iPads are cheaper, faster and more accessible than ever. For marketers this means a major shift in the way we conceptualize, approach and actualize online and offline marketing strategy will soon be in order. In this 25-minute #SMX West session MobileMoxie CEO Cindy Krum will discuss the future of mobile marketing with a specific focus on the importance of cross-device compatibility and big data.
Read more of #SMX Liveblog: The Coming Paradigm Shift In Mobile Marketing (#ms2).
February 17, 2014
Is iBeacon a Wearable Technology Gateway Drug?
Now companies have a new way to learn your secrets, er, we mean help you get the most out of your brick and mortar shopping experience. It's called iBeacon and it's an indoor positioning system that allows in-store transmitters to send signals to nearby iOS 7 and Android devices.
iBeacon technology lets marketers do amazing things (four of which we cover in this post), but is it also a wearable technology gateway drug?
(Spoiler alert: I think it is. Do you?)
Read more of Is iBeacon a Wearable Technology Gateway Drug?
January 17, 2014
Mobile User Experience is Mobile Optimization: Using Google's PageSpeed Insights Tool for Mobile
Google is serious about user experience on mobile devices. Until recently there haven't been many tools to analyze a mobile user experience or mobile optimization efforts. Last August Google gave webmasters a tool to validate mobile optimization through its PageSpeed Insights tool. Much like GTMetrix and other page speed tools, Google's tool reports specific items that may be a hindrance to optimal site performance for both desktop and mobile platforms.
SEOs familiar with the selection of page speed evaluation tools on the market will likely recognize a common limiting factor. Each page speed tool I've ever used only goes so far as tell you what the problem is, with very few telling you how to fix it. For example, a typical page speed tool may report that a site has a lot of thumbnail images and the page may benefit from using CSS sprites – something like that. But none of the tools will suggest why this observation is important, at least from a mobile perspective.
Google's PageSpeed Insights tool defaults to the mobile tab (we can read between the lines however we want), but newly added to the tool is a User Experience section which is currently in beta. Click-through for the insights this tool provides and what that tells us about Google's prioritization of mobile user experience.


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Ava Checks Your Work Week Weather ForecastUPDATED 7:14 PM EDT Apr 15, 2012
Meteorologist Ava Marie takes a look at the weather for the beginning of the work week.
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CommentsThe views expressed are not those of this site, this station or its affiliated companies. By posting your comments you agree to accept our terms of use.blog comments powered by Disqus


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We regret that due to the technical limitations of our site, we are unable to offer eBooks or Audio Downloads to customers outside of the UK.
For further details please read our eBooks help.
Yet Another Introduction to Analysis (eBook)Victor Bryant
Mathematics education in schools has seen a revolution in recent years. Students everywhere expect the subject to be well-motivated, relevant and practical. When such students reach higher education the traditional development of analysis, often rather divorced from the calculus which they learnt at school, seems highly inappropriate. Shouldn't every step in a first course in analysis arise naturally from the student's experience of functions and calculus at school? And shouldn't such a course take every opportunity to endorse and extend the student's basic knowledge of functions? In Yet Another Introduction to Analysis the author steers a simple and well-motivated path through the central ideas of real analysis. Each concept is introduced only after its need has become clear and after it has already been used informally. Wherever appropriate the new ideas are related to school topics and are used to extend the reader's understanding of those topics. A first course in analysis at college is always regarded as one of the hardest in the curriculum. However, in this book the reader is led carefully through every step in such a way that he/she will soon be predicting the next step for him/herself. In this way the subject is developed naturally: students will end up not only understanding analysis, but also enjoying it.
Publisher: Cambridge University Press


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Priority scheduling helps to reduce the wait time for new patient appointments to within 5 working days for most specialities. Based on your insurance, location and language, we can quickly match you to the physician or specialist you need.
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Select Local Merchants
Harvey's Smoke House BBQRead MoreChow down on ribs, slaw and more at Harvey's Smoke House BBQ, a down-home barbecue joint in Cutler Bay. If slimming down is on the agenda, note that the food here is anything but low in fat. Little guys and gals will also love dining at Harvey's Smoke House BBQ, which offers a family-friendly environment (and menu). Harvey's Smoke House BBQ caters to all party sizes, both large and small. Diners who appreciate a no-frills environment come to Harvey's Smoke House BBQ in jeans and a hoodie. Grab your meal to go at Harvey's Smoke House BBQ if you're in a hurry — or better yet, have them bring it to you through their delivery service! You can also have Harvey's Smoke House BBQ cater your next event. The neighboring lot provides free parking to guests. You won't break the bank at Harvey's Smoke House BBQ, with a meal typically hovering below the $15 mark.20218 Old Cutler RdCutler Bay, FL US
Any Lab Test FastRead MoreAny Lab Test Fast empowers people to chart their personal health without enlisting a middle man. Their certified staff provides clients with the same battery of lab tests medical professionals often order, letting the clients themselves choose which health tests they wish to take even if they don't have a doctor's referral or a white lab coat. These tests—ranging from vitamin-deficiency tests to viral-fatigue panels to cholesterol checks—are conducted in accordance with HIPAA and state law standards.10720 Caribbean BlvdCutler Bay, FL US
Sailaway Yacht Charter ConsultantsRead MoreGet your sea legs ready! Sailaway Yacht Charter Consultants in Miami provides quality vessels so you can have a boating experience that is both relaxing and fun. Parking is plentiful, so patrons can feel free to bring their vehicles.9771 Wayne AveMiami, FL US
Lady of America Fitness CenterRead MoreLady of America Women's Fitness Club spreads female-focused wellness across the nation by furnishing each of its franchise locations with equipment and classes designed with women's bodies in mind. Each locale stocks a strength-training area with machines sized specifically for the feminine frame, and ellipticals and stationary bicycles help to chisel gams without transporting users across state borders. Instructors conduct such group classes as kickboxing, belly dancing, and Zumba aboard a floating aerobics floor, whose softened surface diminishes stress on joints. Throughout each facility, personal trainers patrol public zones to acquaint guests with exercise gear or host one-on-one sessions. Depending on the location, clubs might also include complimentary onsite childcare, brow dabbing, and amenities ranging from infrared saunas to manicures.18491 S Dixie HwyCutler Bay, FL US
Saga Bay Food StoreRead MorePick up a ready-made dinner or some ingredients from Saga Bay Food Store in Cutler Bay and take a break from your busy day to enjoy a nice meal. A classic breakfast option, cereal is always good to have on hand. A box is sure to ease everyone's morning appetite without taking too much time off the clock. Pick up a loaf of freshly-baked bread from Saga Bay Food Store and create that tasty sandwich you've been craving all day. Health-conscious eaters will love cooking with the fresh produce available here. Dial down your thirst with some delicious drinks that are both refreshing and cool. We all could use a little dairy in our diet, so why not add some to your day and pick it up at Saga Bay Food Store? You'll feel great knowing you're getting just the right nutrition. When all you want to do is relax after a long day, cooking is the last thing on your mind. Eat a delicious meal in a matter of minutes with an easy-to-make TV dinner! Who has time to cook anymore? That's why there are frozen foods available here to help you keep pace with your career and family. When you don't have time to grab lunch or dinner, these tasty snacks will hold you over until you can take a break. Pick up some fresh and tasty pasta from Saga Bay Food Store and slurp your way to happiness. Find a large array of bold and flavorful coffees and teas at Saga Bay Food Store and sip your way through tasty goodness. Chicken, beef, sausage, and more are all available from this fine establishment for your cuisine. Don't settle for bland meals. Add some pizzazz to your food with an extensive selection of seasonings and spices. Health-conscious eaters will love the wide selection of fish on hand. You'll definitely want to make sure you're well stocked for any potential emergencies by browsing through Saga Bay Food Store's great selection of canned foods. If you're just getting into cooking, pick up some oil and vinegar from here and learn the basics of cooking with these necessities. This store has all the supplies you need to make a scrumptious dessert when your tastebuds are calling. With a bottle of water in hand, it's easy to refresh and refuel. Grab a couple drinks from Saga Bay Food Store and stay on the go all the time. With available parking nearby, Saga Bay Food Store is easily accessible by car. Cooking is a great way to unwind after a long day so pick up some groceries from Saga Bay Food Store in Cutler Bay and cook up a tasty and healthy meal.20285 Old Cutler RdCutler Bay, FL US
Nestle Toll House Cafe By ChipRead MoreFor fresh and high-quality grocery items that will keep for days, head on over to Nestle Toll House Cafe by Chip in Cutler Bay. Don't get enough dairy in your diet? Dairy products from this store are sure to deliver all the nutrients you need. Add some produce to your next dinner plate for a delicious meal jam-packed with vitamins and nutrients. When you're a busy parent on the go, shopping at Nestle Toll House Cafe by Chip for some canned food might be the perfect way to save you hours a week. If you always seem to have one foot out the door, breakfast can be tricky. For a quick and easy solution, a box of cereal is right up your alley. A healthy and light snack from Nestle Toll House Cafe by Chip is a great way to keep your energy up throughout the day. Whether you're a double shot of espresso or a jasmine tea, this place has you covered. Packed with essential nutrients, be sure to try walk away with some delicious fish for dinner. Don't let the amazing deals at this place pass you by. When you stop in today, you'll be able to browse an absolutely fabulous selection of vinegar and oil that can mean transformative changes to your cuisine. Switch up your weekly pasta routine with a new and exciting pasta recipe. Grab some noodles from Nestle Toll House Cafe by Chip and get cooking. Health nuts will go crazy for the refreshing beverages available here, a great way to stay happy and hydrated. With a bottle of water in hand, it's easy to refresh and refuel. Grab a couple drinks from Nestle Toll House Cafe by Chip and stay on the go all the time. Nestle Toll House Cafe by Chip serves up the most delicious freshly-baked bread in town. Head on over and pick up a loaf today. Whether you pop it in the microwave or warm it up over the stove, the frozen food here is ready to eat. For baked goods that are as delicious as they are fluffy, don't forget to pick up some fresh ingredients to make sure your creation hits it out-of-the-park. Just a pinch of one of the seasonings and spices available here will help take your meal to greatness. You'll be able to save time with any of the TV dinners available here. Five minutes is all that's stopping you from total relaxation with these delicious meals. You'll want to taste the exquisite meats available at this location. The area has many parking options for customers. It's time to browse the aisles and aisles of groceries at Nestle Toll House Cafe by Chip. Just head to Cutler Bay now.20505 S Dixie HwyCutler Bay, FL US


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WordReference can't translate this exact phrase, but click on each word to see its meaning:
what does he look like
Forum discussions with the word(s) "what does he look like" in the title:
how /what does he look like? for physical appearance - grammarSee Google Translate's machine translation of 'what does he look like'.
what does he look like? / what is he like? - grammar
What's he like? and What does she look like? - grammar
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A new test that examines large sections of the sentinel lymph node for genes expressed by breast cancer could reduce the risk of recurrence and multiple surgeries, doctors say.
The GeneSearch Breast Lymph Node Assay, manufactured by Veridex, L.L.C., a Johnson & Johnson company, is being used at the Medical College of Georgia to examine half of the tissue in the sentinel lymph node, the first place breast cancer typically spreads. The sample represents more than 10 times the amount of tissue examined in traditional biopsies.
And because the test examines the tissue with molecular tools, it is more sensitive, says Dr. Zixuan (Zoe) Wang, molecular biologist and scientific director of MCGs Georgia Esoteric and Molecular Diagnostic Labs, L.L.C.
When we look at the tissue with the GeneSearch test, we are looking for excessive amounts of mamoglobin and cytokeratin 19, both genes that are expressed more in breast cancer tissue, Dr. Wang says. If those genes are present in excessive amounts, we know the cancer has metastasized.
MCG is the first place in Georgia to offer the test, which Time Magazine named one of the top-10 medical breakthroughs of 2007.
Done during a lumpectomy, the GeneSearch test uses molecular diagnostic methods to examine more tissue than traditional sentinel node biopsies, reducing the chance of false negative results, says Dr. Stephen Peiper, chair of the MCG Department of Pathology and Georgia Cancer Coalition Distinguished Cancer Clinician and Scientist.
The sentinel node, located in the armpit, filters fluid from the breast.
During a traditional sentinel node biopsy, a surgeon would remove a node, then the pathologist would cut that section in half and cut that section to a quarter of the original sample size, Dr. Peiper says. They then would cut wafer-thin slices from those sections, freeze and stain them, and look for cancer cells under a microscope. This technique, call
|Contact: Jennifer Hilliard
Medical College of Georgia


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1993 Ford Escort LX 4dr Sedan
A great little car. It would be even
better if I had not taken it to
horrible places such as All Tune and
Lube in Fairfax. They fixed one thing
and destroyed another...Having a great
mechanic is important, and I think
with the help of one, the Ford Escort
93 can keep going and going and going.
1993 Ford Escort LX 4dr Wagon
I have been very pleased with this car. I am an
active outdoor enthusiast and have taken this
car places where others with two wheel drive
wouldn't go. The front wheel drive is excellent.
I have had virtually noproblems with this car
until recently when it started missing. Turns
out the plugs and wiring and timing belt were
all still original and should have ben replaced
30,000 miles ago anyway! So now that it has
been it is running great again.
car came from michigan. on way back the
car averaged approx. 35 mpg. since i've
had it has been back and forth to west
virginia. my wife drives it every day,
to and from work and personal use. it
is an absolute incredable car. overall
a complete two thumbs up! i don't
intend to get rid of it.
my favorite features are: great fuel
mileage and very fun to drive for a
small wagon.
i'm very pleased with this car. no
improvements needed.
1993 Ford Escort LX 4dr Hatchback
Been driving this car for 50,000 miles
and haven't spent a dime on it except
for regular maintenance. Alas it's too
weak to drive on the highway with more
than one person in the car, but if you
spend most of your time in the city,
you can't do better bang for your
buck. Highway fuel economy averages to
35 mpg.
hatchback increases cargo room
considerably, reliability
more power (added in later models),
more responsive steering
I've had my navy blue wagon since I
drove it off of the dealer's lot.
This car has never left me stranded.
Replaced heater core (leaking coolant
in '99 $400), and the ignition ('03
$200). The ignition gave out when I
was at PepBoy's so, I wasn't really
stranded... Other than these items
and routine maintenance, everything
else is original. The
A/C still blows ice cold air during
hot TX summers, never serviced. I've
since bought a new
car but couldn't bare to trade it in.
In fact, I drive this car more than my
new minivan. ODO - 114K.
Dependable, good gas mileage, low
maintenance cost, and 4-star front and
side crash rating. Safety feature:
thanks to the peeling black plastic
seals, no one will steal my wagon.
I must agree on the black seal on top
of doors and the cup holders. I've
spilled too many drinks from taking
sharp turns as well. Cloth on sun
visors are coming apart from the hot
Texas sun.
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