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It's very rare for me to want to return to hotels, even when they are as good as they get, as I much prefer to keep moving on. However for Maison MK I am ready to go back at my first opportunity. I felt so very relaxed there. The accommodation is fantastic but its the staff that make the real difference between a great stay and one that is exceptional. Top marks.
- Official Description (provided by the hotel):
- Maison MK is a cool, romantic, sophisticated house right in the middle of the Marrakech medina. Everything in the riad is curved and organic. Our six beautiful rooms are creative, rich, romantic, decadent and totally indulgent! Brand new in Jan 2008, we have wow-factor suites, spa loveliness, stunning lighting, and cutting edge design. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Odigeo, Agoda and Priceline so you can book your Maison MK reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Maison Mk Marrakech
- Maison Mk Hotel Marrakech


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Fragrance Captures The Scent Of London Zip Codes [Pics]
Bex London created four unisex scents inspired by four of the city's busiest areas.
They say smells can bring us to places based on our memories. What happens if we wear scents that are inspired by actual places?
Perfume brand Bex London has created four scents that are inspired by landmark zip codes in London. The scents are unisex and named after the zip codes that they represent.
Londoner SE1 recalls the Thameside spice wharf, while N6 has English fruit and pink pepper and bergamot. EC2 brings lime, lemon, grapefruit and juniper berry into the mix while W1X has the more feminine scents of rose, iris and jasmine with precious woods and vanilla.
Bex London was founded by Rebecca Goswell who worked with Francois Robert, a 4th generation perfumer, to create the unique fragrances.
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PSFK Labs Presents
The Future of Connected Life
The New Consumer and Their Journey to Effectiveness, Balance & Personal Growth

subset: commoncrawl


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Los Angeles Clippers v Charlotte Bobcats
Mo Williams of the Los Angeles Clippers shoots the ball past DeSagana... Nieuwsfoto'sBal,Basketbal,Basketbal - NBA Pro,Charlotte - North Carolina,Charlotte Hornets,DeSagana Diop,Los Angeles Clippers,Maurice Williams - Basketballer,North Carolina - Staat,Schieten,Sport,Sportwedstrijd,Time Warner Cable Arena,Treffer,Verenigde Staten,VerticaalPhotographer Scott CunninghamCollection: National Basketball Association 2012 NBAECHARLOTTE, NC - FEBRUARY 11: Mo Williams #25 of the Los Angeles Clippers shoots the ball past DeSagana Diop #7 of the Charlotte Bobcats during the game on February 11, 2012 at Time Warner Cable Arena in Charlotte, North Carolina. NOTE TO USER: User expressly acknowledges and agrees that, by downloading and/or using this Photograph, user is consenting to the terms and conditions of the Getty Images License Agreement. Mandatory Copyright Notice: Copyright 2012 NBAE (Photo by Scott Cunningham/NBAE via Getty Images)


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Tide tables and solunar tables for sport fishers in Johns Pass. Find out the forecast for high tides and low tides before setting out to fish, and other fishing-related data such as the lunar phase, tidal coefficient, sun and moon rising and setting times, hours of maximum fish activity, weather conditions in Johns Pass ...
We want you to enjoy to the max a well-planned fishing expedition! Good luck!
Today Tuesday, 6th of October of 2015, the sun rose in Johns Pass at 7:27 am and sunset will be at 7:11 pm. The moon rose in the east (72º) at 1:58 am and will set in the west (287º) at 3:29 pm.
In the high tide and low tide chart, we can see that the first low tide was at 1:16 am and the next low tide will be at 2:56 pm. The first high tide was at 7:06 am and the next high tide will be at 9:59 pm.
The lunar phase is a Waning Crescent. Today we have 11 hours and 44 minutes of sun. The solar transit is at 1:19 pm and the length of time the moon will be visible will be 13 hours and 31 minutes.
The tidal coefficient today is 44, a low value, which means that the range (difference between high tide and low tide) will be lower than on other occasions and the currents will also be small. At noon the tidal coefficient increases to 48 to end the day with a tidal coefficient of 52. The tide heights today are 1.6 ft, 2.3 ft, 0.7 ft and 2.0 ft. We can compare these levels with the maximum high tide recorded in the tide tables for Johns Pass which is of 3.0 ft and a minimum height of -1.0 ft.
The solunar fishing calendar in Johns Pass tells us that today is a bad day for fishing, the fish activity forecast is low, however, this is just a chance so we encourage you to take your rod and try it during solunar periods. Please, read more about solunar tables. The best times of day for fishing are:
Tide timetable for Johns Pass. The times are generated in local time in Florida (Gulf Coast) and the daylight saving time change is calculated automatically, so you don't need to add or subtract anything. You will also have the lunar phase, sunrise and sunset times, the tidal coefficient and the average fish activity forecast for each day according to the solunar tables:
[ 0 low activity ] , [ average activity ] , [ high activity ] , [ very high activity ]
NOTE: The times reflected in the tide table for Johns Pass are tide forecasts only valid as references for sport fishing. They shouldn't be used as a guide for navigation. The heights are expressed in feet referenced to Mean Lower Low Water (MLLW).
MLLW is the average of the lower low water height of each tidal day observed over the official time segment over which tide observations are taken and reduced to obtain mean value (Tidal Datum Epoch).
33708 Johns Pass
USA: AL | CA | CT | DC | DE | FL (east) | FL (gulf) | FL (west) | FL (keys) | GA | LA | MA | MD | ME | MS | NC | NH | NY | OR | PA | RI | SC | TX | VI | WA
Start of summer time UTC-4
March 8, 2015 at 2:00 am ► 3:00 am
End of summer time UTC-5
November 1, 2015 at 2:00 am ► 1:00 am
There are 26 days left until the clocks change
|1:16 am
|low tide
|( 1.6 ft. )
|7:06 am
|high tide
|( 2.3 ft. )
|2:56 pm
|low tide
|( 0.7 ft. )
|9:59 pm
|high tide
|( 2.0 ft. )
|coefficient 0h
|coefficient 12h
|Activity of the day
Major periods
from 8:43 am to 10:43 am and from 9:10 pm to 11:10 pm.
minor periods
from 1:58 am to 2:58 am and from 3:29 pm to 4:29 pm.
Waning Crescent
Moon age: 23 days
Light: 40 %
|Northern Hemisphere
|New Moon (6 days)
October 12, 2015 at 8:06 pm
|First Quarter Moon (14 days)
October 20, 2015 at 4:31 pm
|Full Moon (21 days)
October 27, 2015 at 8:05 am
|Last Quarter Moon (27 days)
November 3, 2015 at 8:24 am
|1:58 am
|Lunar transit
|8:43 am
|3:29 pm
|Duration of the moon
|13 h 31 m
|7:27 am
|1:19 pm
|7:11 pm
|Duration of the sun
|11 h 44 m
Earth - Sun
Angular diameter
Earth - Moon
Angular diameter


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East Naples United Methodist Church
Sunday, October 04, 2015
Music is an integral part of what we do at East Naples United Methodist Church. Our Director of Music, Linda Matthews creates engaging music ministry opportunities for all ages. During our worship services we feature music from our amazing Chancel Choir, Hope, and special music performances. We are blessed to have a gifted organist, LaVon Mattson and guest instrumentalists throughout the year. We invite you and your family to come and join us as we sing praises to our King.
Do you have a talent to share? Contact Linda Matthews to see where you can be used for the glory of God at East Naples UMC. firstname.lastname@example.com
East Naples UMC Concert Series: 2015-2016
Weekly Music Calendar
Various musical selections in all services provided by the Chancel Choir, Special Vocalists or musicians, or small groups.
Private Piano Lessons: 3:45pm - 4:45pm
Ladies' Breakfast Fellowship: 8:30am Cracker Barrel at 951 and Davis Blvd. (open to all ladies)
Private Piano Lessons: 3:30pm - 4:00pm
Chancel Choir: 7:00pm - 9:00pm
Learning Center Music: 10:00am - 11:00am
Hope (Ladies Small Group): 2:00pm - 4:00pm


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The ASGE Recognized Industry Associate
(ARIA) program is designed to enhance the
interactions between clinicians and industry representatives. Those
industry representatives who successfully complete a pre-test, a full
day of intensive training, as well as a post-test, are awarded the ASGE
Certificate of Completion, granted the use of the ASGE ARIA Program logo
on their business cards, and receive a number of other prestigious
recognition benefits marketing tools.Congratulations to the ARIA Industry Training Graduates! ASGE is proud of their accomplishments
and salutes their commitment to professionalism in the GI industry.
Boston Scientific Corporation
Stephanie Gonzalez
Anthony J. Vari
Bracco Diagnostics, Inc.
Ali Duman
Cardinal Health
Linda C. Logan
Keith Kraskinski
Cook Medical
Greg Skerven
Brenda Spain-Stewart
Jacki Grosu
Brian Johnson
Wanda L. Molari
EndoChoice, Inc.
Perry Mykleby
EndoGastric Solutions, Inc.
Daniel Sinclair
Endoscopy Division of FUJIFILM Medical Systems USA, Inc.Erik AndersonCory AnsonChris ArbuckleJames ByrneJason ClabornPaul CorbinRickey DavisMatt JonesMike LacheyAnthony LaMantiaBrian ShieldsKim SmithChris TrussAnders WeaverChuck WilsonChris Wlezien
Epix Anesthesia
Kirk Dennis
ERBE USA, Inc.
Johnny BoatrightChuck BremsPaul FawbertJohn HancockKen HirschDuke NguyenValerie PadawerPaul Romano
Fractyl Laboratories Inc. Michael BurkaAndrew HollettSara Morneau
GI SupplyCaitlin D'EntremontBryan FritzJos KerstensLisa SzpakIronwood Pharmaceuticals
Philip Malone
Medigus Ltd.
Tom Dempsey
Lori Saper
MEDIVATORSNick B. Bromiley
Merit Medical EndotekStephen BarnettSteve CapelutoKevin ColleranLindsey DavisPaul DrakeMatt ElkinsAlireza ForouzandehBrian HuppertsBrian KaneAmanda KimballDendra LanhamJohn ReynaudWilliam VonDranCharlie Wagner
Olympus Corporation of the Americas
B. Earl Adamy, IIIRichard LessigBenjamin MatsilDanielle Puccino
PENTAX Medical Laurie BrightLaura BustamantePeter Popolo
Sedasys, a Division of Ethicon Endo-Surgery, Inc. Christy Cooper
Spectrum Surgical Jared RobeyYvonne Solomon
US EndoscopyWilliam BusbyTony Siracusa
For more information on the ARIA Industry training Program, including scheduling group training for your organization, contact Linda kay Tyler, director of Sales and Business Development, at email@example.com or by phone at (630) 570-5601.


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Mesenchymal Stem Cell-based Therapy: A New Paradigm in Regenerative Medicine Neeraj Kumar Satija1, Vimal Kishor Singh1, Yogesh Kumar Verma1, Pallavi Gupta1, Shilpa Sharma1, Farhat Afrin2, Menka Sharma1, Pratibha Sharma1, R.P. Tripathi1 and G.U. Gurudutta1* 1Stem Cell & Gene Therapy Research Group, Institute of Nuclear Medicine & Allied Sciences, Lucknow Road, Timarpur, Delhi-110054, India. 2Department of Biotechnology, Hamdard University, Hamdard Nagar, New Delhi-110062, India. Received date: 12-Aug-08, Revised date: 27-Mar-09, Accepted date: 7-Jul-09*Corresponding author: Dr. G. U. Gurudutta Stem Cell & Gene Therapy Research Group, Institute of Nuclear Medicine & Allied Sciences, Lucknow Road, Timarpur, Delhi-110054 INDIA Phone: 91-11-23905144 Fax: 91-11-25737049 Email: firstname.lastname@example.com Please cite this article as a "Postprint";10.1111/j.1582-4934.2009.00857.x has yet to undergo copy-editing and proof correction. See http://www.blackwell-synergy.com/loi/jcmm for details. approved for publication in the Journal of Cellular and Molecular Medicine, but This is an Accepted Work that has been peer-reviewed and
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Abstract Mesenchymal stem cells (MSCs), adherent fibroblastoid cells, present in bone marrow and many other tissues can be easily isolated and expanded in vitro. They are capable of differentiating into different cell types such as osteoblasts, chondrocytes, adipocytes, cardiomyocytes, hepatocytes, endothelial cells and neuronal cells. Such immense plasticity coupled with their ability to modulate the activity of immune cells makes them attractive for stem cell-based therapy aimed at treating previously incurable disorders. Preclinical studies have reported successful use of MSCs for delivering therapeutic proteins and repairing defects in a variety of disease models. These studies highlighted the in vivo potential of MSCs and their ability to home to injury sites and modify the microenvironment by secreting paracrine factors to augment tissue repair. Their therapeutic applicability has been widened by genetic modification to enhance differentiation and tissue targeting, and use in tissue engineering. Clinical trials for diseases like osteogenesis imperfecta, graft-versus-host disease and myocardial infarction have shown some promise demonstrating the safe use of both allogeneic and autologous cells. However, lack of knowledge of MSC behaviour and responses in vitro and in vivo forces the need for basic and animal studies before heading to the clinic. Contrasting reports on immunomodulatory functions and tumorigenicity along with issues like mode of cell delivery, lack of specific marker, low survival and engraftment require urgent attention to harness the potential of MSC-based therapy in the near future. Keywords: mesenchymal stem cells, stem cell therapy, genetic modification, protein therapy, tissue engineering
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List of main topics: • Introduction • Mesenchymal stem cells and its characteristics • Experimental/Preclinical MSC-based studies o MSC transplantation o Genetically modified-MSC-based therapy o MSC-based protein therapy o Tissue engineering using MSCs • Clinical studies • Challenges and future prospects
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Introduction Bone marrow harbours cells of hematopoietic and non-hematopoietic lineages and their precursors, known as stem/progenitor cells. The non-hematopoietic stem/progenitor cell compartment contains mesenchymal stem cells (MSCs), which are involved in remodeling of the mesenchymal tissues throughout adult life. These multipotent cells are easily isolated from bone marrow and are capable of expansion and differentiation into mesodermal lineage cells including osteoblasts, chondrocytes and adipocytes, under appropriate conditions, in culture [1, 2]. This led to the evaluation of their potential for treating diseases, and the birth of MSC-based therapy. Recent clinical trials with MSCs for treating debilitating disorders like osteogenesis imperfecta, myocardial infarction, stroke and graft-versus-host disease have shown some promise [3-6]. Numerous preclinical studies have established the therapeutic potential of MSCs in tissue engineering and as cellular protein factory for delivery of cytokines and anticancer agents [7-9]. Genetically modified-MSCs have also been successfully evaluated in animal models for diabetes, skeletal defects and myocardial infarction [10-14]. Cotransplantation of MSCs with hematopoietic stem cells (HSCs) has been documented to improve HSC engraftment in mice [15, 16]. Though there has been a surge in preclinical and clinical trials using MSCs, caution must be taken in planning such studies since MSC biology is only beginning to be understood. However, the question arises: what makes MSCs unique and preferable for cell-based therapies? In this review, we focus on the suitability of MSCs in the field of regenerative medicine. We provide an overview of the current status of research on MSC-based therapies in
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experimental animals and humans. Different therapeutic designs along with preclinical cases which also address the mechanisms of MSC action are discussed. Clinical trials with MSCs are critically evaluated followed by a discussion on the controversies surrounding the use of MSCs and the challenges that need to be overcome for translation of the therapy from the bench to the clinic. Mesenchymal stem cells and its characteristics MSCs were first identified about 30 years ago by Friedenstein and colleagues as an adherent fibroblast-like population in the bone marrow capable of differentiating into bone [17]. Since then MSCs have been isolated from the human bone marrow based on their ability to adhere to tissue culture plastic [1]. Though occurring at a very low frequency of 1 in 10,000 to 100,000 bone marrow mononuclear cells, these cells are capable of proliferating in vitro without significant loss of differentiation potential during early passages [1, 2, 18]. Originally isolated from the bone marrow, similar populations have also been isolated from peripheral blood [19], periosteum [20], umbilical cord blood [21], synovial membrane [22], trabecular bone [23], adipose tissue [24], limbal stroma [25], amniotic fluid [26], lung [27], dermis and muscle [28]. These populations have been functionally characterized based on their ability to differentiate into osteoblasts, chondrocytes and adipocytes in culture upon induction due to lack of specific markers for MSCs [29]. However, phenotypically they are defined as positive for CD105, CD73 and CD90, and negative for hematopoietic markers (CD34, CD45, CD11b and CD19) and HLA-DR [30]. Since these surface markers are used for characterizing cultured MSCs, immense efforts are underway to identify markers for their direct isolation from tissue. Positive selection approaches using antibodies against low-
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affinity nerve growth factor receptor [31], stage-specific embryonic antigen (SSEA)-1 [32] and SSEA-4 [33] have been used for isolation of primitive MSCs. Transplantation of a single cell-derived population of SSEA-1+ mesenchymal cells in mice is the first in vivo study demonstrating their capability of differentiating into different mesenchymal cell types, thus showing their true stem cell properties. However, these cell populations were similar phenotypically but heterogeneous in their functionality since all clones did not demonstrate same differentiation potential suggesting only enrichment of MSCs using these markers. Antibodies have also been raised against MSCs for their prospective isolation such as STRO-1, SH-2, SH-3 and SH-4, but none of them recognize an epitope exclusively present on MSCs [34]. Though the use of non-homogenous MSCs in preclinical and clinical studies has proved safe and effective (as will be discussed ahead), the search for surface markers exclusive to MSCs for their isolation and characterization is extremely important. Playing a role in the homeostasis of mesenchymal lineages, these cells differentiate into osteoblasts, adipocytes, chondrocytes, tenocytes, myoblasts and stromal fibroblasts [1, 35, 36]. Recent identification of various MSC populations such as mesodermal progenitor cells (MPCs) [35], marrow-isolated adult multilineage inducible (MIAMI) cells [37], very small embryonic-like stem cells (VSELs) [38] and SSEA-1+ mesenchymal cells [32] have demonstrated their differentiation into mesodermal, endodermal and neuroectodermal lineages, such as cardiomyocytes, hepatocytes, neural cells and endothelial cells [32, 35, 39-41]. Hematopoietic differentiation has also been observed upon transplantation of SSEA-1+ cells in mice, signifying their primitiveness compared to all other populations [32]. However, the transdifferentiation potential of MSCs has been questioned due to differences in the MSC populations, culture conditions, experimental models and evaluation methods [42]. Many of the observed morphological changes could be a culture artifact or a result of fusion with
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somatic cell [43, 44]. Therefore, a thorough evaluation of the plasticity of MSCs in vivo is essential since in vitro conditions might not represent the true in vivo milieu. Another distinguishing feature of MSCs is their ability to expand in vitro under normal culture conditions [2]. We have observed 88- to 560-fold expansion in a single passage (15-20 days) upon culturing early passage MSCs at a density of 50-500 cells/cm2 [our unpublished data]. Colter et al have reported extensive expansion of a subpopulation of MSCs, designated recycling stem (RS) cells, to the order of 109-fold in 6 weeks by culturing cells at low density of 1.5 or 3 cells/cm2 [45]. Clinical feasibility of culture expanded MSCs has been validated by a number of studies [4, 46-49]. Thus, a small amount of bone marrow aspirate is sufficient for generation of large number of cells needed for transplantation following in vitro expansion. Immunological characterization of human MSCs revealed intermediate expression levels of human leukocyte antigen major histocompatibility complex (MHC) class I, and no expression of MHC class II antigen and costimulatory molecules CD40, CD80 and CD86 [50-52]. The expression of MHC class I prevents them from the action of natural killer cells while absence of costimulatory molecules leaves T cells anergic [reviewed in 53, 54]. In addition, MSCs have been demonstrated to suppress T lymphocyte proliferation and activation [50, 51]. As a consequence, MSCs are able to modulate the immune response making them immune privileged and suitable for allogeneic transplantation, as has been reported in numerous clinical studies [3, 55, 56]. Further, MSCs have been reported to home to sites of injury and disease following intravenous infusion and contribute to the repair process [5, 48, 57]. The expression of chemokine receptors on MSCs might be responsible for their ability to sense and respond to signals like chemokines expressed by injured tissues [58], causing them to
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extravasate from the blood vessels, like immune cells [59], via a coordinated rolling and adhesion behaviour on endothelial cells in a P-selectin- and VCAM1-dependent manner [60]. Their contribution to tissue repair is also mediated by secretion of paracrine factors having angiogenic and anti-apoptotic properties [61-63]. These paracrine factors not only attract endothelial cells and macrophages but are also likely to stimulate the resident stem/progenitor cells to aid in the process of tissue repair [64]. MSCs can be easily isolated from readily accessible blood and bone marrow compared to other stem cells from tissues like brain, heart and liver [65, 66]. Additionally, ex vivo expansion potential enables generation of a sufficient number of cells for transplantation [45]. Immunomodulatory functions, homing ability to injured sites and capability to modify the microenvironment by paracrine factors makes intravenous delivery feasible in comparison to site-specific delivery of neural [67], cardiac [68] and muscle stem cells [69]. Thus, making MSCs a promising candidate for stem cell-based therapy (Figure 1). Experimental/Preclinical MSC-based studies Capitalizing the extraordinary properties of MSCs, several studies have been undertaken to evaluate their potential for tissue repair in animal models. Depending on the type of disease/injury, different strategies involving site-specific delivery, genetic modification and use of scaffolds have been designed. Basic studies to identify the mode of action of MSCs and their responses to damages have also been addressed highlighting the therapeutic potential as well as safety and efficacy of using MSCs. However, certain issues remain to be resolved before translation of MSC-based therapy to the clinic (Figure 2).
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MSC transplantation To begin with, numerous studies using systemic administration of MSCs have been performed at preclinical level to assess their in vivo behaviour and suitability for the treatment of a number of injuries and diseases (Table 1). Ortiz and colleagues evaluated the ability of intravenously infused MSCs in bleomycin exposed mice, which represents a lung injury model, to engraft in the lung tissue [70]. Bleomycin treatment resulted in 23-fold increase in engraftment levels of MSCs compared to mice not exposed to bleomycin. Further, the engrafted cells adopted an epithelium-like morphology and reduced bleomycin-induced inflammation and collagen deposition in the lung [70, 71]. Whether MSCs actually underwent transdifferentiation into alveolar epithelial type II cells or fused with epithelial cells was not evaluated. However, transplanted mice exhibited increased level of G-CSF and GM-CSF which might have mobilized endogenous stem cells aiding in repair [71]. The anti-inflammatory action of MSCs was mediated by secretion of IL-1 receptor antagonist (IL1RN) which suppressed expression of pro-inflammatory cytokines TNF-α and IL-1α [72]. In vitro migration assays demonstrated the release of, as yet unknown, chemotactic factors from damaged lung cells which attracted MSCs to the injury site [71]. Shimizu's group standardized transdifferentiation of MSCs into keratinocytes in culture and investigated whether MSCs could migrate and engraft into wounded skin in murine model. They found that intravenously injected MSCs transdifferentiated into keratinocytes, endothelial cells and pericytes at the wound site, thereby accelerating the repair process [73]. Evaluating the migratory mechanism using in vitro and in vivo migration assays, they identified chemokine receptor CCR7 to play a major role since its ligand SLC/CCL21 induced MSC migration [73]. Expression of keratin by transplanted MSCs and formation of glandular structures was reported by Wu and colleagues upon injection of MSCs around
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wound in an excisional wound splinting model in diabetic mice [74]. They observed reduction in the number of donor-derived cells in the wound during the 4 week follow-up suggesting that MSC effects are transient and do not provide long-term self-renewal stem cells for keratinocytes. Since MSCs have also been observed to return to the bone marrow after wound healing [75], the local concentration of the chemokine signals or the expression of a particular chemokine in response to injury at the site might have a significant role in retaining MSCs [76], which needs further evaluation. Apart from undergoing transdifferentiation, MSCs are also likely to contribute to the repair process by secreting paracrine factors including VEGF-α, EGF, keratinocyte growth factor, SDF-1, IGF-1 and Angiopoietin-1 (Ang-1), which facilitate the recruitment of macrophages, keratinocytes and endothelial cells to the wound site and enhance angiogenesis and wound healing [63, 74]. Thus, reduction in inflammatory responses and accelerated angiogenesis contribute to the ongoing reparative process but functionality of MSC-generated tissue like sebaceous and sweat glands, if any, is not known. Therefore, complete regeneration of the tissue is debatable [77]. Similarly, transplantation of human MSCs in hyperglycemic NOD/SCID mice resulted in homing to islets associated with an increase in pancreatic islets and mouse insulin production [78]. No human insulin was detected in blood and the reduction in blood glucose levels was mainly a result of stimulation of islets and β-cell [78-80], similar to that observed for neural stem cells in mice [81], as well as inhibition of T cell responses against the new β-cells [82] These studies bring to light the potential of MSCs to migrate to injury site and modify the microenvironment, thereby modulating the immune response and facilitating tissue repair by stimulating endogenous stem/progenitor cells. It is, therefore, necessary that studies suggesting transdifferentiaion clearly define the experimental conditions and thoroughly
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evaluate the true nature of the differentiated cells by expression profiling and functional assays. Genetic marking approach may be useful in assessing the differentiation potential of putative MSCs upon transplantation in animal model systems [83]. Further, these animal models represent excellent systems to elucidate the mechanism of action of MSCs in mediating various therapeutic effects, in order to improve the present treatment regimens and facilitate the development of new approaches. Recently, MSCs have also been shown to improve hematopoietic transplantation [15, 16, 47, 84, 85]. Transplantation of HSCs is used for the treatment of oncohematological disorders, but marrow ablative therapy (involving high dose chemotherapy and radiotherapy) destroys not only hematopoietic cells but also damages the stroma [86, 87]. This is likely to cause reduction in the engraftment of HSCs in the hostile environment as has been demonstrated in mice [88], thereby, decreasing the success of transplant. Koc et al reported rapid hematopoietic recovery in 28 breast cancer patients undergone high-dose chemotherapy following coinfusion of HSCs and MSCs [47]. Enhanced hematopoietic engraftment was also reported upon infusion of limiting number of umbilical cord blood stem cells with unrelated MSCs in mice [84]. Co-transplanting MSCs with HSCs (CD34+ cells) has been shown to improve engraftment in the bone marrow in mice, though the underlying mechanism needs to be elucidated [15, 16]. This will not only help in improving the present regimens to enhance HSC engraftment, but represents a useful strategy that can be employed to enhance success of transplantation of other adult stem cells, as documented by increased survival of MHC-mismatched skin grafts in immunocompetent baboons [89]. Migration of MSCs to the sites of injury and disease has also been well documented in animal models for myocardial infarction and cerebral ischemia [90, 91]. Also, culture expanded
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human MSCs have been shown to home to radiation-injured tissues in NOD/SCID mouse model [92]. This portrays their ability to sense and respond to damage signals, thereby avoiding the need for targeted delivery (such as intramyocardial, intrahepatic) to damaged tissues. However, intravenous infusion would cause distribution of cells throughout the body reducing the fraction of cells homing to the damaged site [93, 94]. Another issue is entrapment of a large fraction of cells in the lung [90] resulting in very low engraftment levels of the order of 0.1% to 2.7% in the tissues [3, 93]. In vitro expansion of MSCs is also likely to result in low homing as demonstrated in murine study [95], but whether human MSCs also exhibit similar effect remains to be determined. Another contributing factor is low cell survival rate after transplantation [96, 97]. Thus, preconditioning of MSCs prior to transplant by culturing in presence of SDF-1 [98] or under hypoxic conditions [99, 100] are useful strategies which enhance cell survival in the hostile environment in vivo. Such preconditioning leads to the activation of Akt survival pathway as well as increased expression of pro-survival and pro-angiogenic factors like hypoxia-inducible factor 1, VEGF, erythropoietin, Ang-1 and Bcl-2. Also increased expression of c-met leads to higher migration rates to ischemic tissue in response to secreted hepatocyte growth factor as demonstrated in rat hind limb ischemia model [100]. Further studies using disease models need to be carried out to elucidate the molecular mechanism involved in MSC homing for the improvement of current therapies. For instance, studies have revealed the involvement of integrin β1 in MSC migration and engraftment in ischemic myocardium in mice [101], whereas CD44 has been implicated in migration and localization of MSCs to kidneys in mouse model of acute renal failure [102]. Cytokine-mediated up-regulation of CXCR4 expression in Flk1+ MSCs improved their engraftment in bone marrow of sublethally irradiated NOD/SCID mice [103] while ectopic expression of α4
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integrin on mouse MSCs resulted in significant increase in bone specific retention of transplanted MSCs in mouse [104]. These studies offer molecular targets for genetic engineering of MSCs to enhance their homing and engraftment to injury sites and accelerate recovery. Alternatively, cytokine treatment of MSCs to enhance expression of tissue-specific adhesion molecule or tissue-specific administration of chemotactic factor like SDF-1α [105], CCL12 [73] and MCP-3 [76] is likely to facilitate targeting to a particular tissue. Genetically modified-MSC-based therapy Integrating the strengths of genetic engineering and stem cell biology holds tremendous potential for designing treatments for critical injuries and diseases by inducing differentiation into a specific lineage and improving adhesion potential. Following transplantation, the fate of MSCs would be determined stochastically in vivo depending on the niches they home and therefore, not all transplanted cells might contribute to the repair of the damage. As recently demonstrated in mice, transplanted MSCs differentiated into osteoblasts in the heart [106]. Thus, site-specific transplantation of functional, differentiated cells would be advantageous under certain conditions. Though differentiated cells can be generated by chemical stimulants or differentiation factors in vitro, the differentiation state might not be stable upon transplantation. Such reversal of differentiation (i.e. dedifferentiation) has been shown in vitro for MSCs upon the withdrawal of stimulants [107]. Therefore, genetically modifying stem cell by a key differentiation factor would help to achieve directed and complete differentiation into the desired lineage. Studies on the therapeutic applicability of genetically modified - MSCs (GM-MSCs) have been carried out in animal models (Table 2). MSCs transduced with BMP2 and BMP4 have been shown to successfully repair a variety of musculoskeletal defects in animal models as
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BMPs are potent inducers of osteogenic differentiation [11, 12, 108]. The cells not only themselves undergo differentiation but also stimulate the neighbouring cells to participate in the repair process. It has also been reported that short-term expression (for 6 days) of BMP-2 in MSCs was sufficient to irreversibly induce osteochondral bone formation upon implantation into tibialis anterior muscle or joints of SCID mice [109]. Differentiation being a process coordinately regulated by number of factors, expression of combination of genes has proved more fruitful for orthopedic gene therapy. BMP-2/7 and BMP-4/7 heterodimers exhibit higher activity than homodimers, therefore, simultaneous transduction with BMP-2 and BMP-4 or BMP-7 in mesenchymal cells resulted in 2- to 3-fold more bone formation in mice [110, 111]. However, BMPs are secreted factors and their constitutive overexpression is likely to cause abnormal bone formation in vivo. Therefore, regulated overexpression of osteogenic transcription factor Runx2 (using tetracycline-regulated Tet-Off expression system) has been demonstrated to offer control over osteoblast differentiation of engineered MSCs in mice [112]. These engineered cells provide a novel approach for treatment of osteochondral disorders and use of regulateable expression systems to prevent undesirable effects, but studies aimed at mapping the fate of GM-MSCs following repair of the defect are required before leaping at the prospect of using them for human clinical trials. Use of GM-MSCs has been investigated in culture as a choice for the treatment of genetic disorders. Genetic modification of MSCs with dominant-negative collagen type I protein successfully repaired bones derived from osteogenesis imperfecta patients [113], whereas dystrophin-transfected MSCs participated in myogenesis through cellular fusion and complemented the genetic defect of muscular dystrophy myotubes in vitro [114].
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Generation of cells of different tissues for the purpose of transplantation can also be achieved by genetic modification. Pancreatic transplantation is the only cure for type 1 diabetes patients. However, shortage of pancreas donors calls for the development of alternative cell-replacement therapy. Transdifferentiation of human bone marrow-MSCs into insulin-producing cells by overexpression of pancreatic duodenal factor 1 (PDX1) has been achieved in vitro [10, 115]. Only 50% of the cells expressed insulin and secreted it in response to glucose in culture while other islet hormones were expressed by all cells. Since these cells did not differentiate completely in vitro, as determined by microarray, transplantation under the renal capsule in streptozotocin-diabetic immunodeficient mice induced further differentiation and resulted in the reduction of hyperglycemia and stabilization of blood glucose levels during the 5 week follow-up [10]. None of the transplanted cells were observed to migrate to the pancreas, signifying the advantage of site-specific transplantation and avoidance of unwanted effects due to homing to undamaged organs following systemic infusion. However, to assess the maintenance of differentiated state, the cells can be transfected with vector containing GFP or YFP cloned under the control of cell type-specific transcription factor prior to transplantation to evaluate their fate in vivo, specifically when they are transplanted in another tissue/organ since the microenvironment can alter their fate. The cells must also be labeled properly (dyes like PHK26 or genetically like GFP) to track them following transplantation in animal models. For instance, using GFP-labeled Akt-overexpressing murine MSCs, Noiseux et al tracked MSC fate following intramyocardial injection in mouse model of myocardial infarction [116]. They observed transient engraftment of MSCs in the infarct zone and fusion of MSCs with recipient cardiomyocytes as early as 3 days post-injection, raising concern regarding safety and long-term outcome of
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Comet probe Rosetta detects the 'most wanted molecule'
ESA's Rosetta spacecraft has made the first measurement of molecular nitrogen at a comet, providing clues about the temperature environment in which Comet 67P/Churyumov-Gerasimenko formed.
ESA's Rosetta spacecraft has made the first measurement of molecular nitrogen at a comet, providing clues about the temperature environment in which Comet 67P/Churyumov-Gerasimenko formed.
Excitement mounted Thursday as scientists started listening for signs of life from robot lab Philae, hurtling through space perched on a comet some 460 million kilometres (285 million miles) from Earth.
Ground controllers will open a communications line Thursday with a robot lab perched on a comet zipping through space, hoping for signs it is alive, the European Space Agency (ESA) said Wednesday.
The Curiosity rover has temporarily stopped work on Mars while NASA engineers investigate a short circuit.
Spacewalking astronauts successfully completed a three-day cable job outside the International Space Station on Sunday, routing several-hundred feet of power and data lines for new crew capsules commissioned by NASA.
Venus was once considered a twin to Earth, as it's roughly the same size and is relatively close to our planet. But once astronomers looked at it seriously in the past half-century or so, a lot of contrasts emerged. The biggest ...
The European Space Agency says high-resolution images the Rosetta space probe took during a swoop close to a comet it's been tracking for months show boulders on the comet's surface as well as "stunning details of the contrasting ...
Pioneering techniques that use satellites to monitor ocean acidification are set to revolutionise the way that marine biologists and climate scientists study the ocean. This new approach, that will be published on the 17 ...
The European Space Agency (ESA) on Sunday said it had destroyed its last supply ship to the International Space Station, bringing a seven-year venture to a successful close.
A new study of emissions from Martian volcanoes suggests there is no activity going on right now, but researchers aren't ruling out recent eruptions.


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premier inc-class a
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2645 W Alameda Ave
(303) 922-8225
(4 blocks E of Federal)
Driving directions
64 reviews
Moving to or from Denver, CO, 80219? Get FREE truck rental rate quotes at U-Haul at Alameda Ave. U-Haul rental trucks are specifically engineered from the ground up to assist moving families, not freight. Our moving trucks have more safety features than other moving trucks in the industry including gentle ride suspension and high visibility mirrors to assist the driver. Whether you are moving a smaller apartment or a large four-bedroom house, U-Haul truck rentals in Denver, CO will provide you with the moving truck rental you need to get from point A to point B. Find the perfect size moving truck to assist with your move, U-Haul is home of the $19.95 rental truck!
4+ bedrooms
Home 3 to 4 bedrooms
Home 2 to 3 bedrooms
Home up to 2 bedrooms
Apartment up to 2 bedrooms
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Simply click on each moving truck shown above to view individual truck specs including: safety features, towing capacity, fuel economy and of course, the available space-per-truck size. Each rental truck is individually priced to help save you money, time and energy on your move to or from Denver, CO.
U-Haul cargo van rentals and pickup trucks in Denver, CO are perfect for home improvement projects, deliveries and other small loads. Rent cargo vans or pickups to save money on local moving or deliveries. Cargo van and pickup truck rentals are popular with local business, college students and smaller housing moves in Denver, CO, 80219. Our moving van rentals include air conditioning, rub rails to protect your belongings and come equipped with a hitch to tow a trailer rental. U-Haul is the home of the $19.95 cargo van rental in Denver, CO, reserve a van for your moving needs from U-Haul at Alameda Ave!
I drove twenty mile and it costs me fifty bucks....I will give HomeDepot a run next time....way too pricey for what you receive......twenty miles!
Great service
Wait time was a bit long but that happens...
The agent was clueless about whether my insurance would cover any incidents that my occur
Stop charging per day for the dolly rental. This was a bullshit charge purely to increase your income. I will not be using Uhaul unless I have no other option. Also, the tax was higher than the estimate.... seriously, what the hell?! It's a percentage, it shouldn't change when the overall cost is lower other than the tax being lower, not $5+ more. Screw you and your shitty company.
Get some extra help. There was only 1 guy working the entire place. The wait time was long both picking up and returning the rental..
Everything went smoothly and he answered all my questions about out-of-town drop-off.
The owner was extremely helpful when we picked up the trailer from this location! He ensured that we were properly hooked up and secured before we left!
The owner was to stoned to know or care that he had 3 customers waiting. We could see him in his office and all 3 of us tried to approach him because there was no one else around. Finally a hispanic gentleman came in and helped us and was very quick and expeditious with the customer he helped. Unfortunately the owner as said on his shirt was the one that helped us and could barely function. His pupils were huge and his eyes were glossy and bloodshot.
Your rates are to high and I don't understand how I owe you all so much money.when u call that store u can't get in touch with no one direct to that store the call center and the people that work in the store has bad communication. And one person say that u can pay cash for something that u only can use a credit card.
Benjamin was very pleasant!
I arrived at 9am on Sunday and had to wait about 10 minutes for a truck. Wasn't a big problem for me, but by the time I left at 9:20 there was a line 5 people deep and only 1 person (the manager) helping them. He was very nice and helpful, but was clearly in the weeds and all on his own as soon as the store opened.
Get there early if you're in a hurry!
Great employees, vehicle rented was new and super clean, drove nice and a good price. Never rent from budget again.
maintenance light was on, but no big deal they made note and the truck performed excellent.
Everything was great! I was in and out quickly. My charges were exactly what I expected and the staff was friendly and helpful. Great experience. Will definitely rent again!
Fill the potholes in your parking lot , please!
Everyone was very professional and friendly and very willing to make sure my rental fit my needs.
The salesman told me I had to get the insurance from them because mine wouldn't cover--not true. And, this location apparently charges twice as much as others--$19.95 every 12 hours instead of daily (24 hours). The additional charges ended up being almost $50 more than expected. I will never rent from them again.
I went to pick up my 17' truck and was on time. When I arrived, the store manager, who was working the desk, informed me that they didn't have a 17' truck and issued me a $50 credit for not having it. When I told him that I had movers coming in 30 minutes and that I needed a truck, he told me there was nothing he could do for me, never even making eye contact with me the entire time. I went to my car and called the 800#. After 20 minutes, I found someone who told me that there was a 15' truck at my current location and they reserved it for me on the spot. I went back in, waiting in line, and got the truck. Why couldn't the store manager have offered a different truck, either one smaller or larger? My movers ended up arriving while I was still at the store trying to get a truck, which messed up the whole timing of my move. It's simple customer service that if you don't have what the customer needs, you offer something else. Apparently not at this location. I will not be returning or recommending this location.
The Office was pretty warm so they could cool it down some when its so hot outdoors but the office was well maintain and personal were very professional
Keep the good work;)
Didn't have the size truck I reserved.
The "Tall Guy" could use some motivating or maybe a bit more customer service training. Other than that, my interactions with everyone else have been great and I have yet to have any issues throughout my numerous visits to this location.
Staff was difficult to find, hard to engage in customer service, less than eager to share knowledge on products, and overall very difficult to do business with. There was a line of 4 people at the counter, and the young girl with long black hair was in the back working with a manual on a Subaru Outback, while we stood patiently waiting. I feel staff didn't prioritize their duties in the most efficient manner to ensure customer satisfaction. I had a 9:15am pick up appointment and waited 15 minutes until anyone even recognized my existence. Will not be returning to this location.
It just seemed as though we were an inconvenience on the sales associate, especially when we first arrived. I did not feel welcomed.
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U-Haul International, Inc.'s trademarks and copyrights are used under license by Web Team Associates, Inc.
To reserve by phone, call 1-800-GO-UHAUL (1-800-468-4285)


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HP Photosmart 7150 and Windows 7
I am trying to add an old HP Photosmart 7150 Printer to my Windows 7 64-bit system. I read something on the Microsoft webpage that said the two were not compatible, but I just want to make sure that that is true. It looks like there is a driver for Windows 7 when I looked up the printer on the HP website, but it says it downloads with the Windows Updates. Is Windows 7 compatible with this old printer? Do I have to download anything manually?
Re: HP Photosmart 7150 and Windows 7
Did you ever find the answer? I'm trying to do the same thing.
Re: HP Photosmart 7150 and Windows 7
I have Windows 7 Pro edition and it loaded for me ok on a reboot and had been working fine until just recently. Didn't have to download anything and I dont think there is even anything available on the HP website for pro edition other than a utility.
- HP Printers - Installing Your Printer Driver Using the Windows Built-in Solution
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" For larger views of any of the photos (1200 x 800) - please click on the individual images INTRODUCTION My introduction to DUNU Topsound (18 months ago) was with their triple hybrid DN-1000, which rapidly became a hit with Head-Fi buyers, and was one of the first triple hybrid IEMs to show that top quality could be achieved at an affordable price. Since then DUNU has been a consistent..." --Brooko
DUNU DN-2000 Hybrid 3 way earphone
" Introduction Hello head-fiers! Now, you're going to read a review of a spectacular earphone named Dunu DN-2000! It's a hybridized earphone consisting of two Balanced Armature (BA) drivers and a 10 mm dynamic driver; although the driver configuration isn't specifically described in their main website, I assume it has one TWFK (or two-in-one BA) driver that covers the treble and mid-range and..." --Gandasaputra
Logitech UE 900s Ultimate Ears Noise-Isolating Earphones (NEWEST 2014 VERSION)
"UE 900S Unibody I would like to first say thank you to Mrs. McDonald for sending me a demo unit to review. UE has some of the best customer service that I have experienced, they are very fast in responding to any emails with questions that I had. I am not employed or I am being compensated by UE for this review, this review is based on my opinions and all the photos were taken by..." --acain
Dunu TITAN 1 — titanium-coated diaphragm earphones
" For larger views of any of the photos (1200 x 800) - please click on the individual images INTRODUCTION My introduction to DUNU Topsound (over a year ago) was with their triple hybrid DN-1000, which rapidly became a hit with Head-Fi buyers, and was one of the first triple hybrid IEMs to show that top quality could be achieved at an affordable price. I lost touch a little with DUNU..." --Brooko
Dunu DN-1000
"Hybrid 3 ways: 2x Balance Armature + 1x 10mm Dynamic driver http://www.dunu-topsound.com/DN-1000.html I was a bit disappointed with DN-1000 when I tried it out of the box. The treble was a bit metallic with the stock silicone eartips. The first few weeks with DN-1000, I used foam eartips, Comply T-500, that smoothen the treble, made the DN-1000 sounds very open and airy, but..." --earfonia
DUNU DN-22M Detonator. Headphones earphones
" Introduction: Dunu by Top-Sound is famous for good price to performance earbuds as well as the amount of accessories they include with their very well built units. Dunu introduces the Detonator as an earbud for phone users so that people can catch calls and talk. This earbud features a microphone with push function terminated by a V angled jack. Now let's see what Dunu has to offer this..." --bowei006
Dunu DC4
DUNU is a fairly new company and was started as a brand of the Top Sound OEM making IEMs that utilize very high quality housings that have a similar look and feel, but better build quality to the Monster IEMs. I have had a chance to hear some DUNU products briefly, but as I now stick to custom IEMs and higher priced universals I didn't perform a full evaluation. I was a little surprised...
Logitech UE 900
"This is my first review so keep that in mind. I bought a pair used UE 900's at Cex, an electronics resale store in San Francisco. I was cleaning them and pulled the wrong way on the MMCX connector and the freakin' right unit came apart and ripped the internal wires apart. I contacted Logitech tech support and was shipped a complete UE 900s for a replacement! They were quick and helpful..." --caffed
Logitech Ultimate Ears 600 Noise-Isolating Earphones - Dark Silver
"should have added a cable clip , fitting is awesome , sound quality is just what i like , bass is fast , hits with a punch , really nice mids , highs are lively too . thick and dark signature , my fav sig . secoend in command of my line up , might let the xba-3 creep in between , but xba-3 lacks sound stage , come on xba-3 , being a $200 phone you can not lack sound stage . but xba sounds fine..." --suman134
DUNU DN-13 Crius
" First off, I'd like to thank the folks at DUNU-TopSound for providing me with samples to review Up for review today are a pair of balanced armature based IEMs. Priced solidly within the bracket I would consider "mid-range", these have a great deal of competition right out of the gate and one has to wonder whether or not DUNU's newcomers can stand up to that competition...." --TheGame21x


text:
Why Buy from Bold Rugs?
- Free Shipping and No Sales Tax (On Orders Over $99)
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Safavieh Braided BRD173A Beige and Brown Area Rug
|Ships Within
|Style: Braided
|Collection: Safavieh Braided
|Material: Polypropylene ()
|Weave: Hand Made
|Country of Origin: India
|Color(s): Brown >> Secondary Color(s):Beige and Brown
Questions? Click Here or Call 1-888-989-RUGS (7847)
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|The Safavieh Braided BRD173A Beige and Brown by Safavieh is sometimes listed with the following brand codes: BRD173A-24, BRD173A-26, BRD173A-3OV, BRD173A-3, BRD173A-28, BRD173A-210, BRD173A-4, BRD173A-4OV, BRD173A-214, BRD173A-6R, BRD173A-6SQ, BRD173A-5, BRD173A-5OV, BRD173A-6, BRD173A-8OV, BRD173A-8, BRD173A-9. Also, the following UPC codes: 683726802693, 683726997160, 683726802686, 683726997184, 683726802709, 683726997108, 683726802716, 683726997191, 683726997139, 683726802747, 683726802754, 683726802723, 683726802730, 683726997207, 683726802778, 683726802761, 683726997214
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- Safavieh Braided BRD308A Blue and Multi
- Safavieh Braided BRD164A Multi
- Safavieh Braided BRD311A Black and Grey
- Safavieh Braided BRD315A Green
- Safavieh Braided BRD166A Multi
* Disclaimer: Because of differences in computer monitors we are not responsible for differences in colors shown in rug pictures on your computer screen. Also, we cannot accept orders with pricing errors due to typos or other human errors. Please email us or call us at 1-888-989-7847 if you have any questions about colors, stock availability or any other questions you might have.


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|3121 Cardinal Lake Drive
|40 reviews
|37 Kendall Street
|20 reviews
(770) 502-3674
3121 Cardinal Lake Drive, Duluth, GA 30096 map »
other locations »
Green South Insulation is one of the largest full service insulation companies in Atlanta, specializing in all insulation applications for commercial and residential projects. Our goal is to provide customers with the most comprehensive information to help them make the best decision on their insulation. At Green South, we have certified professionals trained to help you make decisions.. to increase your buildings comfort and decrease energy costs. Our company employees are insured, trained and certified to install spray foam, blown in fiberglass, or all types of reflective radiant barriers. We provide a relaxed, enjoyable and informative assessment of your insulation needs.
We are an authorized distributor of FOAMETIX Spray Foam Insulation. FOAMETIX is a series of light density polyurethane spray-applied foam insulation systems that protect your health, seal your structure and save you money.
Since we handle all aspects of insulation, we are not a "one-size-fits-all" company. Each home is unique. Each home needs its own assessment. One of the problems we see in the industry is most insulation companies specify one type of insulation and discredit the others. We install all types of insulation and most brands. We take the time to work with the each individual to make sure they create a healthier, quieter and more energy efficient indoor environment.
Want to speak with a pro on the phone?
Have a question?
Need answers?
We offer the most comprehensive hassle free warranty!
Contact us today to find out how FOAMATIX Spray Foam, blown in fiberglass, or radiant barrier can increase your homes comfort and decrease your energy cost.
770 502 3674
2012, 2013, 2014
Green South Insulation is a member of: GAHBA (Greater Atlanta Home Builders Association), SPFA (Spray Polyurethane Foam Alliance), USGBC (US Green Building Council), IGCC (International Green Construction Code), and NAHB (National Assciation of Home Builders).
* 24-Hour Service Available
[PDF] Green South Insulation Customer Savings Letter
[PDF] Frequently Asked Questions
Green South Insulation uses products that are labeled as eco-friendly using renewable energy sources. FOAMETX Spray Foam "Our Foam is Green" is free of toxic air contaminates and environmentally sound. You can feel safe with Green South Insulation.
After a consultation and price for insulating under the floor of our sunroom, we were on the schedule within a week. Mr. Martin was on time and he and his assistant were very efficient from set up to... completion of our project. Everything that we were expecting was done as well as cleaning up afterwards. I would highly recommend Russell Martin to anyone for foam insulation needs. Excellent job!VIEW MORE »VIEW LESS »
Green South Insulation did an excellent job with the project. Everything that Russell stated in his quote was completed and exceeded my expectations. Russell handled all aspects of the project: ... the inspection, the quote, and the installation. It was great to only work with one person through the process. The job was expected to take 2 full days, and Russell arrived each day at the time stated, and worked throughout the day. He kept me informed through the whole process, and answered any questions or concerns during the job. We are already noticing the difference in how the house is cooled, and cannot wait until we see the difference in our energy bills.VIEW MORE »VIEW LESS »
Russell and Alan did a great job adding blown insulation to my 45 year old home. Russell�s estimate was fair and he did not try to upsell me as I experienced with others. They also installed new attic stairs at my request and went the extra mile to be sure all went back together as it should have. They were clean, efficient and a pleasure to do business with.
After a consultation and price for insulating under the floor of our sunroom, we were on the schedule within a week. Mr. Martin was on time and he and his assistant were very efficient from set up to completion of our project. Everything that we were expecting was done as well as cleaning up afterwards. I would highly recommend Russell Martin to anyone for foam insulation needs. Excellent job!
Green South Insulation did an excellent job with the project. Everything that Russell stated in his quote was completed and exceeded my expectations. Russell handled all aspects of the project: the inspection, the quote, and the installation. It was great to only work with one person through the process. The job was expected to take 2 full days, and Russell arrived each day at the time stated, and worked throughout the day. He kept me informed through the whole process, and answered any questions or concerns during the job. We are already noticing the difference in how the house is cooled, and cannot wait until we see the difference in our energy bills.
Reviews: 1
Posted on: 8/5/2015
Green South recently upgraded our insulation in our attic. Russell team did an excellent job! It has made a huge difference in our heating already and will definitely make a big impact on our energy bills. They were great to work with, gave a lot of suggestions, and walked us thru the entire process to understand what we needed. I chose them after an extensive search for the best in town and found them to be the best! It was a fair price for excellent quality and service. I would recommend them to anyone looking for new/upgrade insulation.
Reviews: 3
Posted on: 6/19/2015
I have a Goliath of an attic - old, hot,huge and treacherous. Russell, Tony and Philip worked endless hours for a solid week transforming my hot, hot attic into a wonderfully inhabitable place. They are a FIRST CLASS company and first class people. I am so glad that I chose them for this work after we did some careful research. I am an interior designer, and I will be referring them in the future without hesitation.
After some research and quotes, I decided to go with GreenSouth Insulation for my insulation needs. Russell and Tony both did an excellent job replacing my blown in fiberglass with open cell foam in the attic as well as closed cell foam in my crawl space. They arrived early every morning and worked a schedule to ensure me and my wife wouldn't be delayed on a scheduled vacation. Every day they made sure to clean behind themselves in our home. Once the job was done they left everything as it was when they arrived. Russell was very detailed in providing information as to their progress as well. Also, when he identified an electrical issue in my crawl space, he made sure to let me know. This could have cost me big time if he had chose to not worry about it. It was clear that they treated your home with the utmost respect. Both acted professionally during the project and were a pleasure to have on the job. I would certainly use them again and recommend them to any of my friends and family.
Russell was a pleasure to work with from our initial meeting and quote through the job completion and clean up. He and Tony were very professional and took great care of my home while completing the job. I would highly recommend GreenSouth to anyone who has any insulation needs. Good people who do great work.
I got attic insulation work done by Green South insulation. Russel and Tony did a fantastic job. They were on time and did everything they promised to do on the project quote. Keep up the good work guys. We are happy that we did not get this done from anyone else. *****
Reviews: 5
Posted on: 3/25/2014
We recommend Green South Insulation! We had 4 other quotes for the same product (open cell spray foam)and Russell was somewhere near the middle; he was fair and reasonable. Most importantly, I felt confident working with Russell and Alan. They just finished installing spray foam insulation in our very large attic. They are both very professional, were on-time every day, and very respectful of our home. Russell kept me apprised every step of the way so I always knew exactly what they were doing, how long it would take. They cleaned up every day. We feel this is a great product for our home. We look forward to seeing lower utility bills soon!
Russell came out and did a free estimate. We made an agreement on price and he did what he said he would do, when he said he would do it. Had a couple estimates and his was not the lowest (close to it though); however, I felt that he would be the best for the job and I was right. Was warned that some of the ceiling tiles in my basement apartment may be damaged through no fault of their own, which is understandable); however, none were after all! Highly statified customer.
After a recent furnace repair and excessive propane usage it was recommended that we enhance our home insulation. Russell came by to analyze our house and was very thorough and knowledgeable about his products and services. He explained everything in layman's terms and was very straight forward about options and cost which we really appreciated. Russell and team went above and beyond, repairing a hole in the closet ceiling and re-framed the attic entrance. We had 2 feet of insulation blown into the attic, radiant barrier applied to specific areas and the Foametix spray foam under the entire house. All of this occurred during the recent snow/ice storm which extended the project time frame which Russell and team worked around successfully. During and immediately after we noticed an incredible temperature change throughout the house. Days after we noticed our furnace does not kick on constantly like it used to and the house seems to maintain a constant comfortable temperature. We are very pleased with the services Russell provided and will be recommended Green South insulation to friends and neighbors. -Laith Renno
Our house is nearing 30 years old and had some legacy insulation issues. Russell professionally assessed the situation and provided a variety of recommendations. He and his team blew in insulation and it has made a tremendous difference in the draftiness of the house. His team was courteous, professional and timely. They were in and out with minimum disruption and left everything clean. I highly recommend them.
Reviews: 1
Posted on: 8/28/2013
I can't say enough positive about this company. Russell Martin is as professional as they come. From "estimate" to "job completion" I was thoroughly satisfied. The whole team was prompt, friendly and respectable and they treated my home with kid gloves and even made friends with our pets! The foam insulation is already making a huge difference and it hasn't even been 24 hours. I know the investment was worth it and the fantastic customer service was over the top. Not only will I tell all my friends, I'll show them!
I had multiple quotes for my home to have spray foam insulation installed. Russell came in and quoted the project explaining what they would be doing. His quote was "in the middle" of the pack for pricing. I choose Green South Insulation based upon my interaction with Russell, fairness of price and the reviews on Kudzu and Home Advisor. He quoted 5 - 5.5" of open cell foam (approx. R-19). Make sure to make an "apples to apples" quote comparison because some folks will not spray insulation that thick. Russell and his team were conscientious of the surroundings and cleaned up daily (2 days for the project). They were professional and I will refer them to others. Job well done.
Reviews: 3
Posted on: 8/19/2013
We had radiant barrier and blown in insulation done to our 1928 home. Being an old home, it had it's challenges and Russell was very prompt in coming out to discuss and to schedule when we were ready. His team showed up on time and were very polite and did a great job. I would recommend them to anyone. We are looking forward to saving on our energy costs to cool our old house's second floor. Thanks !


text:
Real Estate Management and Development
Company Overview of S.D. Malkin Properties Inc.
Executive Profile
N. George Host
Chief Operating Officer, S.D. Malkin Properties Inc.
|Total Calculated Compensation
|This person is connected to 1 Board Members in 1 different organizations across 2 different industries.
See Board Relationships
Mr. N. George Host serves as the Chief Operating Officer of S.D. Malkin Properties Inc. Mr. Host oversees investor relations, joint venture negotiations and legal and tax matters for S.D. Malkin Properties and for value retail Plc. He joined S.D. Malkin Properties since 1988. He represented a Private European Investment Group in retail estate joint ventures that included the development of the one million square foot corinthian. He serves as an Executive Director of ...
Corporate Headquarters
35 Mason StreetPhone: 203-622-1800
Greenwich, Connecticut 06830
United States
Fax: 203-622-3001
Board Members Memberships
Executive Director
Unknown/Other Education
University of Virginia School of Law
Unknown/Other Education
Harvard College
Other Affiliations
Annual CompensationThere is no Annual Compensation data available.
Stocks OptionsThere is no Stock Options data available.
Total CompensationThere is no Total Compensation data available.
|There is no Competitor Compensation data available.
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Fantasy Baseball – Previews And Rankings For Week 8
Every Sunday I'll be giving my preview for the week ahead for Fantasy Baseball. I'll be taking a look at which players have performed the best over the past week, who you should avoid, the best games of the week, and some key two start pitchers to stream.
Two start pitchers:
R.A. Dickey – The knuckleballer is posting another strong season for the New York Mets. This week he'll be facing the Pittsburgh Pirates and the San Diego Padres, two of the worst offences in the majors. Seriously, the Padres and Pirates rank 29th and 30th respectively in runs scored. That's awful. Fantasy Baseball owners couldn't ask for a better match up, so if you're looking for a pitcher to stream grab Dickey while you can.
Jerome Williams – While his matchups aren't as favourable as Dickey's, they're pretty close. Williams faces off against the Oakland Athletics (28th in runs scored) and the Seattle Mariners (20th in runs scored). Jerome Williams isn't a stud, but he's a solid pitcher facing a pair of below average lineups. And that's exactly what a Fantasy Baseball player should be looking for when they stream a pitcher.
Three batters on absolute fire:
Joey Votto - He got off to a slow start, hitting a bunch of doubles but failing to drive the ball over the wall. That all changed this week, as Votto mashed 5 homers, driving in 10 all while hitting 360. Not bad for a guy who one week ago had 2 home runs through the first month and a half of the season.
Andrew McCutchen – It's a good thing the Pirates extended him before the season started, because he's broken out in a big way. He was unstoppable this week, hitting 360 with 4 homers, 8 runs driven in and a stolen base. McCutchen is one of the best players in baseball, and it's time Fantasy Baseball players recognize him as one of the top outfielders in the game.
J.P. Arencibia – He's been on fire over the last couple of weeks, and with the demotion to Adam Lind he was promoted to the middle of the order. Arencibia didn't disappoint, hitting 333 with 4 homers and 10 runs driven in. If you can handle the low batting averages, Arencibia is a nice option to use at catcher in deeper leagues.
Three hitters who couldn't hit the broad side of a barn:
Zack Cozart – The rookie shortstop got off to a great start to the season, but he's stuck in a 1/23 slump right now. Cozart strikes out way too much for a guy without power, and until he cuts down on the Ks pitchers will continue to abuse his poor approach at the plate.
Ike Davis - At some point you have to wonder if the New York Mets will just do Davis a favour here and send him down to the minors. He went 1/17 this week, and his 160 batting average for the season just isn't going to cut it. There's something clearly wrong withDavis, and the Mets need to find a way to get him back on track.
Howie Kendrick - It's been a rough season for Kendrick, and a 1/22 week isn't going to cut it. Given how deep second base is, you shouldn't be using Kendrick on your Fantasy Baseball squad unless you're in an AL only league.
Three pitchers you don't want to mess with:
Justin Verlander – 16 innings, 2 wins, 20 strikeouts, 3 hits allowed and an ERA of 0.56. The scary thing for the American League is that Verlander is pitching better than last year when he won the Cy Young and the MVP.
Josh Beckett – 7 innings, 1 win, 9 strikeouts, no runs allowed. Yes, Josh Beckett pitched a fantastic game against Seattle. Normally I'd put a caveat about him beating a below average lineup, but considering that he'd been getting hit all season it's a step in the right direction.
Kevin Millwood – Turns out he has just a little bit left in the tank. 16 innings, 2 wins, 13 K's and a dominant 0.56 ERA.
Three pitchers hitters can't wait to face:
Chad Billingsley – He got off to a fantastic start, but he's been looking very hittable lately. Billingsley didn't make it out of the fifth in his last start, allowing 4 runs on 8 hits. Not the kind of performance Fantasy Baseball players were hoping for, and it's what makes him such a frustrating pitcher to watch.
Ross Detwiler – Detwiler was looking dominant until this week, throwing 10 innings with a 9.00 ERA. That's just not good enough. Detwiler should rebound though, so don't give up on him.
Hiroki Kuroda – It looked like a terrific signing in the offseason, but so far Kuroda has failed to deliver. This week he allowed 7 runs over 5 innings, getting trashed by the Toronto Blue Jays.
Matchup of the week:
Washington Nationals vs Atlanta Braves (May 25-27)
The Nationals remain the team to watch for the second week in a row. This time they're facing off against the Atlanta Braves, currently holding a 1.5 game lead over the Nats. This series could decide the NL East, and given how important winning the division is you don't want to miss this preview of playoff baseball.
Fantasy Football Waiver Wire: QB Brian Hoyer
Brian Hoyer will re-take his post as starting quarterback for the Houston Texans. Does that make him a viable waiver wire addition for fantasy football owners? Read More
Fantasy Football Week 5 Projection: Drew Brees
Heading into Week 5 of the NFL season, find out what fantasy football owners should be expecting from New Orleans Saints quarterback Drew Brees. Read More
Fantasy Week 5 Dark Horse Sleeper: Jameis Winston
Heading into a Week 5 matchup against the Jacksonville Jaguars, this rookie QB is a super intriguing dark horse sleeper in seasonal and weekly fantasy football leagues. Read More
Celebrity FF Week 4 League Results: Squat Lovers
Find out how celebrities and athletes fare in Week 4 of the fantasy football league season. Here is who's on top, who's in prime position and who should just give up. Read More
Fantasy Football Week 5 Sleeper: Christine Michael
Christine Michael is in line for an increased role for the Dallas Cowboys, but should fantasy football owners buy into any potential for Week 5? Read More
Fantasy Football Week 5 Dark Horse: Dan Herron
RB Dan Herron landed with the Buffalo Bills this week. Can he step into a prominent role right away, and be a fantasy producer in Week 5? Read More
Week 5 Fantasy Football Start or Sit: Mike Evans
Find out whether you should start or sit Tampa Bay Buccaneers WR Mike Evans in Week 5 fantasy football. Read More
Fantasy Football Start or Sit: TE Jimmy Graham
Find out whether you should start or sit Seattle Seahawks TE Jimmy Graham in Week 5 of fantasy football. Read More


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What's happened that I have not heard to push the stock down over 15%. Are we heading for poor earnings? Is there trouble at the top? I've seen nothing but good news on Staples. The stock split should be an indication of the company's faith in the future earnings of the company. So what's up?
Spoke with investor relations today....earnings will be announced 1st week in March...Company says they did not change their guidance to analyst prior to blackout period...says CFO indicates if you look at the history this period each Jan the stock shows similar weakness....if earnings are going to be on target this may be a buying opportunity...
I think that they are due at the end of next month. The Fiscal year ends at the end of Jan.
i recently bought it around 28 and its been declining since then it is hard to understand even though they have announced the split,does somebody know whats going on ,please let us know
I would think that the decline is due to the fear the Staples will have lower than expected earnings for the year. Earnings should be anounced sometime next month. I also think that thereports of poor results by many retail stores for this quarter maybe a factor in this decline. I would also assume that it is due in part to the overall market drop. Staples is a strong company, and I don't think any long term investors should have anything to worry about.
i am in the same situation, i have not see any information indicates the current drop and i really don't understand it. can some please give some reasons to this.


text:
Haha. I get it.
last.fm / mubi
Originally Posted by Avarance
Haha. I get it.
old but still can make me laugh
[My Anime List] | [last.fm] | [xfire] | [Steam]
*bumps awesome thread*
"I may be a baby, but I know a nerd when I see one!"
Oh lawd that guy is scary.
And lol at learning Chinese.
Everybody's Gone To The Rapture review! Updated 8/27
Image removed.
Originally Posted by IronyTaken
Image removed.
Are they the people who died?
New Account: http://www.onrpg.com/boards/members/...VoiceOfKarnage
Originally Posted by IronyTaken
I´m a retard.
Not funny.
Hey Ya!
I totally lost
Originally Posted by IronyTaken
man, not here. its not funny here.
Originally Posted by Fullmetal
I totally lost
never seen that before. actually laughed.
To be THIS good takes
Originally Posted by Fullmetal
I totally lost
And I thought they all looked bad before.
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Gabriele Boiselle Mid-Size Friesian Calendar 2014
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Amazing and Sweet 2014 Friesian Calendar!
The Gabriele Boiselle Friesian Calendar displays the photographic works of, Gabriele Boiselle. She is one of the most successful horse photographers in the world. She perceives the special qualities in every horse and is able to capture them with her camera.
Here you can enjoy the black pearls from Friesland which are impossible to resist. The tremendous charisma of these jet black horses with flowing manes and dynamic movement evoke a feeling of bygone times. !
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Natural Gas
How much can we rely on natural gas to help us cut down our greenhouse gas emissions? We get the opinion of leading environmentalist Matthew Bramley.
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|Anna van Buerenplein 13
|2595 DA Den Haag NL +31-70-3817177
|Railway Location
|GDS - Code:
|Mo. - Fr.
|08:00 - 19:00
|09:00 - 13:00
|24 h pickup
Convenient car rental from Sixt is available right at The Hague Central Train Station. Rent a convertible, an SUV, a luxury rental like a BMW 3 series or a compact car such as a Chevrolet Cruze. Sixt Rent a Car has a friendly staff and many well-priced options. Getting a rental car in Den Haag doesn't get easier than with Sixt.
The Hague Central Train Station is the largest railway station in the Dutch city of The Hague and the largest terminal station in the Netherlands. It has links from majors cities such as Cologne, Berlin, Frankfurt, Basel, Prague, Moscow and, of course, Amsterdam. Drive around this 'city of peace and justice' and you will find everything from luxury department stores with international brands to charming little side streets filled with boutiques and specialty shops. See the modern skyline and a historic city center as well as the beautiful North Sea coastline. The beach resort of Scheveningen is part of Den Haag.
Den Haag is internationally renowned for art and culture. The picturesque government complex of the Binnenhof has baroque and classicist architecture going back to before 1230. It used to be a castle complex surrounded by moats. Take a tour through Ridderzaal, aka the Hall of Knights and visit the Dutch parliment there. The Escher Museum features prints, sketches and various material tracing how Escher progressed from realism to his later works of geometrical patterns and optical illusions. The miniature park, Madurodam, has a little bit of everything Dutch. Tulip fields, windmills, canal houses, a cheese market and restaurants with typical Dutch dishes. The multicultural Hague Market is the biggest outdoor market in all of Europe. Visit the 360 degree Omniversum cinema for IMAX-style documentaries. Don't forget to check out the Sixt website for helpful tips and driving information.
|Mo. - Fr.
|08:00 - 19:00
|09:00 - 13:00
|Anna van Buerenplein 13
|2595 DA Den Haag
Sixt Den Haag is located in the New Babylon Center, right next to The Hague Central Station. If you arriving by train, take the exit on the right side of the station. From there it is approximitaly a 200 m walk, until you can see Sixt branch on your left side in the New Babylon Center.
From direction Amsterdam you drive towards Den Haag/Scheveningen. Take the exit Central Station. At the first traffic light drive straight ahead. At the second traffic light, also straight ahead.At the third traffic light you need to turn left and stay in the left lane. That lane is approximitaly 150m long and you will have to turn left, into the Q-PArk garage in the Prinses Irenestreet. The Sixt location is on the first floor right next to the elevators.
If you are walking to Sixt, you only have to go inside the Babylon Center and walk through to the end of it. At the end, turn right and walk along the elevators. The Sixt branch is located next to them. If the Babylon Center is closed, you'll need to walk around the building and you will find Sixt on the backside of the center.
Pick-up out of opening hours is possible for an additional charge. Please provide your e-mail address and mobile number.
|Prinsess Irene Straat
|2595BD Den Haag


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Owners Jeff and Michelle Dow met at the University of Iowa on athletic scholarships for gymnastics. After decorated careers that included spots on the U.S. Nationals team, the duo moved to Lubbock and founded Tega Kid's Superplex in 1995. Assisted by a skilled staff, they entertain and educate kids in teamwork and the athletic arts during sports programs, camps, and events. Though planted in gymnastics classes and fertilized with hand-grip chalk, the 18,000-square-foot facility has blossomed into a diverse space that teaches noncompetitive dance, cheerleading, tumbling, and swimming lessons that follow the USAG Junior Olympic Program's curriculum. The facility also houses a preschool, afterschool activities, and summer events and is a licensed provider of Motion Evolution, an interactive fitness program for kids.
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We offer discount to nonprofits, government agencies, and federal contractors
Recently the handling of civil immigration detainers by local law departments has been heavily scrutinized.
AILA Doc No. 09081163 | Dated August 11, 2009 | File Size: 44 KDownload the Document
An 8/10/09 USCIS update clarifies today the manner in which petitioners for religious workers must notify USCIS regarding their employment of nonimmigrant religious workers in R-1 status under certain circumstances.
[[To print the PDF on this page please use the print function in the PDF reader.]]
Cite as AILA Doc. No. 09081163.Open the Document
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Cameras & Lenses » Camera Lenses » Canon Fit » Canon
Order within 8 hours 35 minutesfor Delivery on Wednesday 14th October
The Canon EF 50mm f1.4 USM lens features superb quality and portability. Two high-refraction lens elements and new Gaussian optics eliminate astigmatism and suppress astigmatic difference. If crisp images with little flare are important to you, they can be obtained even at the maximum aperture with this robust lens. Suitable for use with full-frame and cropped sensor (APS-C) DSLRs. More
Versatile, compact standard-lens design
Gaussian optics, combined with two high-refraction lens elements allow photographers working in all fields to capture crisp, clean images, even wide open at f/1.4. The lens is ideal for photographing landscapes and travel scenes as well as portraits and reportage.
Ultrasonic focusing
A ultrasonic motor drives autofocus extremely quickly, and in near silence. Excellent holding torque ensures the point of focus is reached accurately, without overshooting. Furthermore, full-time manual override is available, making it possible to adjust focus without leaving AF mode.
Smooth background blur
A virtually circular aperture diaphragm gives out of focus regions a softer, more uniform feel. Sharp foreground objects stand out against a smooth blurred background.
Super Spectra coating
Super Spectra coatings ensure accurate colour balance and enhance contrast. They also reduce flare and ghosting – a common problem caused by light bouncing off a camera's sensor.
(based on 49 reviews)
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Canon 50mm f 1.4 lens
By Mike
from Gosport
About Me Hobbyist/Enthusiast
Comments about Canon EF 50mm f1.4 USM Lens:
I am very impressed with this lens; pictures are pin sharp as you would expect from a prime lens. Compared to the f1.8 lens the construction is much better you never feel as if it will fall apart (but I still don't recommend that you drop it!). Even I am not daft enough to get the f 1.2 my bank manager is not that ubderstanding.
Bottom Line Yes, I would recommend this to a friend
Was this review helpful? Yes / No
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Good value
By jakeyboy
from leicestershire
About Me Professional
I was originally after the Sigma 1.4 50mm. Sent 2 back because they missed focus 90%. This lens always hits focus and is quick and reliable, shame it doesn't have the same quality bokeh as the sigma.
enjoying learning
By meg1
from kingston
my first non-zoom lens, still practising with it but results so far have been promising / pleasing.
(1 of 1 customers found this review helpful)
Good general purpose, compact lens
By heddlo
from York
About Me Semi-Professional
I bought this to complement my zooms, but in a small, lightweight unit. I also wanted the large aperture for low light, but more particularly to obtain differential focus. Low levels of distortion are also useful. The lens is somewhat disappointing at full aperture, giving a rather hazy effect on bright objects and indifferent edge definition, but from f/2 onwards it is very usable and by f/8 it is extremely sharp across the frame with no vignetting, etc. On my Canon 5D II this lens needed quite a lot of micro-focus adjustment (+8) to obtain sharp autofocus at wide apertures, but now this has been applied I cannot fault the accuracy of focus. Speed of focus is pretty good too.
(2 of 3 customers found this review helpful)
I'm convinced.
By Tony Smith Photography.
from Wirral, England.
I bought this lens as an upgrade on the 50mm f1.8. I had heard mixed reviews about whether it was worth it or not. I had a little spare cash, which was burning a hole in my pocket, so thought why not.I can honestly say I am not disappointed with it. I've bought from WEX before, and always had great service, this was the same. Very fast delivery, and at a decent price.Loving the low light applications for this lens, and the portrait images I've shot so far.If you can afford the upgrade, I'd say do it, and enjoy a cracking lens on your camera.
Images shared by Tony Smith Photography.
Tags: Made with Product
(1 of 2 customers found this review helpful)
Excellent lens!
By Sharmaine
from Oxford
Very sharp lens, great for portraits! Very pleased with my purchase.
Getting used to it
By KerryN
from Wales
I had hoped to be able to use this lens for low light photography without a flash but so far I have not been able to master this. I am not sure whether it is me missing something but when I look on the internet I see that I am not alone. It is early days in my purchase so hopefully I will figure it out.
Images shared by KerryN
Evening light
Definitely recommend!
By contaktphotography
from leeds
Used mainly for nature and portrait photography.lovely shallow depth of field at 1.4,
Great lens
By Avicenna
from London
Bought this with my canon 6D as L lens equivalent too expensive and 1.8 lens too cheap. Wanred faster aperture lens for low light and portraits. 50mm mimicks human eye view so great to get those shts right. No disappointments.
Good lens
By Ibelwich
from Reading UK
The 50mm is a great versatile lens. Sharp and light I carry it everywhere with me.
Images shared by Ibelwich
Sydney Opera House
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Wex Photographic is a trading name of Warehouse Express Limited (registered as company no. 03366976).
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