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ABSTRACT: RATIONALE Spirometry is the objective measurement to detect airway obstruction. In some patients respiratory symptoms related to airway obstruction are not present, when airway obstruction is detected by spirometry. Aim of the present study was to detect early airway obstruction in an adult population sample in a primary care setting. METHODS Seventeen general practitioners were involved and 912 patients were asked to participate in the study, between January and June 2014: of them, 583 (323M), aged 40-92 yrs, accepted and were investigated through a respiratory questionnaire, the mMRC dyspnoea scale, and spirometry through the Quark PFT (Cosmed, Italy) spirometer. Smoking habits, BMI, respiratory symptoms, doctor respiratory diagnoses, dyspnoea score, and forced expirograms were obtained. Based on answers on doctor diagnosis, we identified 4 subgroups: doctor COPD diagnosis (COPD); doctor Asthma diagnosis (A); Asthma COPD Overlap Syndrome (ACOS); no respiratory diagnosis (NRD). For screening purposes, a FEV1/FVC<70% was considered a marker of airway obstruction. Severity was determined by FEV1 level: I mild (FEV1≥80% of predicted); II moderate (50-79%), III severe (30-49%); IV more severe (<30%). RESULTS One hundred and ninety subjects were current smokers, 235 ex smokers and 155 non smokers. Prevalence rates of cough, sputum, wheezing and dyspnoea were 27%, 26%, 32%, 44%, respectively. Prevalence rates of COPD, A, and ACOS were 12.5%, 7.8%, and 3.6%, respectively. In the overall sample 16.3% (95) showed airway obstruction: of them, 26% mild, 56% moderate, 17% severe, 1% very severe. Among obstructed subjects 12% did not report any respiratory symptom and were distributed among FEV1 levels I-III. Those reporting neither respiratory symptoms nor respiratory doctor diagnosis were 60% in level I; 43% in level II; 44% in level III; none in level IV. In obstructed vs not obstructed individuals, a higher frequency of smokers (χ2=.002) and a higher mMRC score (χ2<.05) were found. A significant association among cough, sputum, wheezing, dyspnoea and obstruction was found (χ2<.001). In a logistic model, wheezing (p=.001), sputum (p=.036), smoking habits (p=.028), and older age (p=.0001) were the best predictors of airway obstruction. CONCLUSIONS We found an elevated prevalence of airway obstruction in our sample of primary care adults associated with elevated respiratory symptoms prevalence and smoking. However, a high prevalence of subjects without symptoms or medical diagnoses was found among obstructed patients, indicating the need of implementing spirometry in family practice as early diagnosis tool.Am J Respir Crit Care Med; 05/2015
Article: An Elevated Body Mass Index Increases Lung Volume but Reduces Airflow in Italian Schoolchildren[Show abstract] [Hide abstract]
ABSTRACT: Asthma and obesity are important and growing health issues worldwide. Obesity is considered a risk factor for asthma, due to the induction of changes in airway mechanics and altered airway inflammation. We cross-sectionally investigated the effect of increased weight on pulmonary function in a large population sample of healthy children, aged 10-17 yrs living in Palermo, Italy. Explanatory effect of weight on lung function variables were evaluated by multiple linear regression models, taking into account height, gender, and age-class. Among the 2,393 subjects, FVC and FEV1 were positively correlated to weight. Multiple regression models showed that the weight beta coefficient for FEV1 was significantly lower with respect to that for FVC (0.005 and 0.009 l/kg, respectively), indicating a different magnitude in explanatory effect of weight on FVC and FEV1. Both FEV1/FVC and FEF25-75%/FVC ratios were negatively correlated to weight, while FEF25-75% was not significantly correlated. Similar results were obtained also when 807 symptomatic subjects were introduced in the model through a sensitivity analysis. In healthy children, the disproportionate increase of FEV1 and FVC with weight produces airflow decrease and consequently apparent poorer lung function independently from respiratory disease status.PLoS ONE 05/2015; 10(5):e0127154. DOI:10.1371/journal.pone.0127154 · 3.23 Impact Factor
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ABSTRACT: AIMS: Here, we present results from a prospective pilot study that was aimed at surveying changes in daily cigarette consumption in smokers making their first purchase at vape shops. Modifications in products purchase were also noted. DESIGN: Participants were instructed how to charge, fill, activate and use their e-cigarettes (e-cigs). Participants were encouraged to use these products in the anticipation of reducing the number of cig/day smoked. SETTINGS: Staff from LIAF contacted 10 vape shops in the province of the city of Catania (Italy) that acted as sponsors to the 2013 No Tobacco Day. PARTICIPANTS: 71 adult smokers (≥18 years old) making their first purchase at local participating vape shops were asked by professional retail staff to complete a form. MEASUREMENTS: Their cigarette consumption was followed-up prospectively at 6 and 12 months. Details of products purchase (i.e., e-cigs hardware, e-liquid nicotine strengths and flavours) were also noted. FINDINGS: Retention rate was elevated, with 69% of participants attending their final follow-up visit. At 12 month, 40.8% subjects could be classified as quitters, 25.4% as reducers and 33.8% as failures. Switching from standard refillables (initial choice) to more advanced devices (MODs) was observed in this study (from 8.5% at baseline to 18.4% at 12 month) as well as a trend in decreasing thee-liquid nicotine strength, with more participants adopting low nicotine strength (from 49.3% at baseline to 57.1% at 12 month). CONCLUSIONS: We have found that smokers purchasing e-cigarettes from vape shops with professional advice and support can achieve high success rates.International Journal of Environmental Research and Public Health 04/2015; 12(4):3428-3438. DOI:10.3390/ijerph120403428 · 2.06 Impact Factor
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ABSTRACT: High levels of indoor NO2 are associated with increased asthma symptoms and decreased expiratory peak flows in children. We investigated the association of exposure to domestic indoor NO2, objectively measured in winter and spring, with respiratory symptoms and lung function in a sample of adolescents from a southern Mediterranean area. From a large school population sample (n=2150) participating in an epidemiological survey in the urban area of the City of Palermo (southern Italy), a sub-sample of 303 adolescents was selected which furnished an enriched sample for cases of current asthma. All subjects were evaluated by a health questionnaire, skin prick tests and spirometry. One-week indoor NO2 monitoring of their homes was performed by diffusive sampling during spring and again during winter. We found that about 25% of subjects were exposed to indoor NO2 levels higher than the 40µg/m(3) World Health Organization limit, during both spring and winter. Moreover, subjects exposed to the highest indoor NO2 concentrations had increased frequency of current asthma (p=0.005), wheeze episodes in the last 12 months (p<0.001), chronic phlegm (p=0.013), and rhinoconjunctivitis (p=0.008). Finally, subjects with a personal history of wheeze ever had poorer respiratory function (FEF25-75%, p=0.01) when exposed to higher indoor NO2 concentrations. Home exposure to high indoor NO2 levels frequently occurs in adolescents living in a southern Mediterranean urban area and is significantly associated with the risks for increased frequency of both respiratory symptoms and reduced lung function. Copyright © 2015 Elsevier Inc. All rights reserved.Environmental Research 02/2015; 138C:8-16. DOI:10.1016/j.envres.2015.01.023 · 4.37 Impact Factor
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ABSTRACT: Rhinitis and conjunctivitis are common diseases worldwide that are frequently associated. Nevertheless, the risk factors for rhinoconjunctivitis are not well-described and the impact of conjunctivitis on rhinitis and asthma in children remains unknown. This study explored the different risk factors and evaluated the burden of rhinoconjunctivitis among adolescents. This was a cross-sectional study conducted on a random sample of schoolchildren, aged 10-17 years, using skin prick tests and a self-administered questionnaire on respiratory health investigating the impact of rhinitis and rhinoconjunctivitis on daily activities. A complete evaluation was obtained for 2,150 children. The prevalence of rhinitis alone was 18.2% and rhinitis associated with conjunctivitis was 20.5%. Rhinoconjunctivitis was more frequently associated with females, a parental history of atopy, domestic exposure to mold/dampness, passive smoke exposure, and reported truck traffic in residential streets. Moreover, rhinoconjunctivitis was associated with a higher level of allergic sensitization. The prevalence of current asthma was 1.7% in subjects without rhinitis or rhinoconjunctivitis, 5.1% in rhinitis and 10.7% in rhinoconjunctivitis. In a logistic model, rhinoconjunctivitis yielded a 2-fold risk for current asthma with respect to rhinitis. Subjects with rhinoconjunctivitis had poorer quality of life (QoL); there was an impact on daily activities in 4.6% of rhinitis and 10.7% of rhinoconjunctivitis. Ocular symptoms increase the role of rhinitis as a risk factor for asthma and its impact on daily activities in children.Allergy, asthma & immunology research 01/2015; 7(1):44-50. DOI:10.4168/aair.2015.7.1.44 · 2.43 Impact Factor
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ABSTRACT: The interaction between IgE antibodies and allergens is a key event in triggering an allergic reaction. The characterization of this region provides information of paramount importance for diagnosis and therapy. Par j 2 Lipid Transfer Protein is one of the most important allergens in southern Europe and a wellestablished marker of sensitization in Parietaria pollen allergy. The main aim of this study was to map the IgE binding regions of this allergen and to study the pattern of reactivity of individual Parietaria-allergic patients. By means of gene fragmentation, six overlapping peptides were expressed in Escherichia coli, and their IgE binding activity was evaluated by immunoblotting in a cohort of 79 Parietaria-allergic patients. Our results showed that Pj-allergic patients display a heterogeneous pattern of IgE binding to the different recombinant fragments, and that patients reacted simultaneously against several protein domains spread all the over the molecule, even in fragments which do not contain structural features resembling the native allergen. Our results reveal the presence of a large number of linear and conformational epitopes on the Par j 2 sequence, which probably explains the high allergenic activity of this allergen.Molecular Immunology 10/2014; 63(2). DOI:10.1016/j.molimm.2014.09.012 · 2.97 Impact Factor
Conference Paper: Higher indoor PM2.5 concentration of cadmium (Cd) and thallium (Tl) is related to domestic smoking[Show abstract] [Hide abstract]
ABSTRACT: Indoor air pollution is estimated to be greater in indoor than in outdoor environment. Tobacco smoke may significantly contribute to indoor air pollution and domestic smoking is correlated to indoor airborne particulates with aerodynamic diameter<2.5µg (PM2.5). Heavy metals, such as Cd and Tl, are present in tobacco and dispersed in the environment by tobacco combustion. In the context of RESPIRA Project, we performed outdoor/indoor measurements of PM2.5 by gravimetric sampling in 73 houses in the Mediterranean Area of South Italy. Gravimetric Teflon filters were analyzed for PM metal content by inductively coupled plasma (ICP) optical emission spectrometry and ICP mass spectrometry for obtaining Cd and Tl concentration. The presence/absence of smokers in each dwelling was investigated by a questionnaire fulfilled by householders. The relationships of indoor/outdoor concentrations were not significant for both Cd and Tl. Conversely, the indoor Cd/Tl correlation was highly significant (R2=.812, p<.0001) showing that both metals in indoor PM2.5 have a common indoor source. Higher concentration of PM2.5 such as of Cd and Tl was associated to the presence of smokers at home: PM2.5 was (median and interquartile range) 24.2 µg/m3 (16.9-41.5) for smoker and 15.7 (10.9-22.5) for non-smoker houses (p<.0001); Cd was 0.148 ng/m3 (0.081-0.449) and 0.032 (0.028-0.080) respectively (p=.0002); Tl 0.069 ng/m3 (0.042-0.146) and 0.020 (0.008-0.042, p<.0001) (Mann-Whitney U-test for nonparametric data). These results suggest that the levels of cadmium and thallium in PM2.5 are markers of third-hand smoking RESPIRA Project was funded by Operational Cross-border Program Italy-Malta 2007-13 code A1.2.3-72.European Respiratory Society Annual congress 2014, Munich; 09/2014
Conference Paper: 10-15 years old children living in Malta are at higher risk for developing allergic respiratory diseases than those living in Southern Sicily[Show abstract] [Hide abstract]
ABSTRACT: Aim of the study was to evaluate the influence of living in highly polluted areas in Malta and in Sicily on reported allergic respiratory diseases in children. Malta has a very high population density while the petrochemical industry located close to Gela is one of the main sources of industrial air pollution in Sicily. In the context of RESPIRA Project, we evaluated 2,047 schoolchildren (972 M), aged 10-15 yrs, selected from 12 junior high schools of Southern Sicily (n=1,189 evaluated subjects) and 6 of Malta (n=858). Children′s parents fulfilled an ISAAC respiratory questionnaire. Rhinitis in the last 12 months was reported by 6.6% in Italy and 7.9% in Malta (p=.05); wheeze in the last 12 months (W12m) by 7.4% in Italy and 12.7% in Malta (p<.0001); doctor diagnosed asthma (DDA) by 7.9% in Italy and 18.1% in Malta (p<.0001). Current asthma (CA), defined as DDA + W12m, was reported by 3.0% in Italy and 7.8.% in Malta (p<.0001). Use of drugs for asthma in the last 12 months was reported by 4.9% in Italy and 12.1% in Malta (p<.0001). In a logistic model, when correcting for asthmatic bronchitis in the first two years of life, parental atopy, early and current passive smoke exposure, mould/dampness at home, personal history for rhinitis, socioeconomic status and presence of pets at home, children living in Malta showed a higher risk factor for CA with respect to those living in Southern Sicily (OR 2.48, IC 1.32-4.70, p=.005). In conclusion, children living in Malta are at higher risk for developing allergic respiratory diseases with respect to those living in Southern Sicily Funded by Cross-border Program Italy-Malta 2007-2013 code A1.2.3-72.European Respiratory Society Annual Congress 2014, Munich; 09/2014
Conference Paper: Total Serum IgE and Specific IgE levels in 10-15 year old Children with Respiratory symptoms and Healthy controls in Sicily and Malta[Show abstract] [Hide abstract]
ABSTRACT: Introduction: The RESPIRA study was performed in the Health District of Gela (Southern Sicily) and Malta in 2012/3 in 11-14 years old schoolchildren (n=2,047) by means of standard respiratory questionnaires (ISAAC),and clinical exam of case and control subjects. Aims and Objectives: To measure total serum IgE levels in cases (n=127, Male=45) and controls (n=142, Male=64), and specific IgEs in cases (n=90, male=53), and controls (n=82, males=38). Materials and Methods: Cases reported wheeze and/or use of asthma medications in the last 12 months, while controls answered negatively to both and also to rhinitis in the last 12 months. The method used for Specific IgE's (sIgE) was that supplied by R-Biopharm (R-Biopharm AG, Landwehrstr. 54, D-64293 Darmstadt, Germany). The method was Enzyme Sorbent Test (EAST). The method used for Total IgE (tIgE) was by ELISA supplied by Genetic Diagnostics (Genesis Diagnostics Ltd, Eden Research Park, Henry Crabb Road, Littleport, Cambridgeshire, United Kingdom). Results: Total Serum IgE (n=269) was raised(>144 IU/l) in 45/127 cases versus 25/142 controls (p=0.0001). In Males 30/76 of cases vs 11/64 controls (p=0.005), while in Females cases 15/51 vs 14/78, (p=0.14). Positive specific IgE (>0.34 U/ml) was noted in at least one allergen in 54/90 cases vs 30/82 controls (p=0.002). HDM was positive in 27/90 cases vs 12/82 controls (p=0.0001), Parietaria positive 12/90 cases vs 2/82 controls (p=0.011), cat 22/90 vs 13/82 controls (p=0.19) in whole sample, while in male subgroup 14/53 of cases were positive vs 4/38 controls (p=0.06). Dog 9/90 cases vs 8/82 controls (p=0.86). Olive positive in 13/90 cases vs 8/82 controls (p=0.48). Alternaria positive in 6/90 cases vs 2/82 controls (p=0.28). Goldenrod Solidago Virgaurea positive in 2/90 cases vs 1/82 controls, and Cladosporium 0/90 cases, 1/82 controls. Conclusion: Positive Total serum IgE, and specific IGE to HDM and Parietaria in all patients were significantly higher in Cases than in control subjects. IGE to moulds and dog allergen was not significantly different. Positive cat IgE was close to statistical significance in males only. RESPIRA Study was funded by Operational Cross-border Program ItalyEuropean Respiratory Society Annual congress - 2014, Munich; 09/2014
Conference Paper: Gender Difference in Skin prick sensitivity to allergens in 10-15 year Cases with Respiratory symptoms vs controls in Sicily and Malta[Show abstract] [Hide abstract]
ABSTRACT: Introduction: The RESPIRA study was performed in the Health District of Gela (Southern Sicily) and Malta in 2012/3 in 11-14 years old schoolchildren (n=2,047) by means of standard respiratory questionnaires (ISAAC) and clinical exam of case and control subjects. Aims and Objectives: To assess sensitivity to common allergens in cases and controls in these southern Mediterranean islands. Materials and Methods: Cases (n=137, M=84) reported wheeze and/or use of asthma medications in the last 12 months, while controls (n=159, M=70) answered negatively to both and also to rhinitis in the last 12 months. Results: A positive skin test (>=3mm) for at least one allergen tested was found in 80/137 cases and 51/159 controls (p=0.0001). House Dust Mite (cases 62/137, controls 28/159, p=0.001), Parietaria (22/137, 10/159, p=0.008), Alternaria (19/137, 9/159, p=0.018), and Blattella (12/137, 5/159, p=0.046) were more frequently positive in cases than in controls. Olive (25/137, 19/159, p=0.142), cat (17/137, 11/159, P=0.116), and dog (9/137, 5/159, p=0.182) did not show a significant difference between cases and controls. Grass pollen sensitization was slightly higher in controls (10/137, 13/159). There was a significant difference by gender in a 2x4 chi 2 comparing positives amongst cases and controls. HDM; Males (cases 41/84 Controls 15/70), females (Cases 21/53, Con 13/89) p=0.011, Olive; in Males (CAS 19/84, Con 10/70) Females (Cas6/53, con 9/89) p=0.007, Cat; Males (Cas.12/84, Con 6/70) Females (Cas.5/53 and 5/89) p=0.019 and for Dog; Males (CAS 7/84 and 2/70) and Females (Cases 2 /53 and 4/89 p=0.017. Conclusion: Skin prick sensitivity to common Mediterranean aero-allergens in asthma patients vs controls was significantly higher in 11-14 year old Males when compared to females. RESPIRA Study was funded by Operational Cross-border Program ItalyEuropean Respiratory Society - annual congress 2014, Munich; 09/2014
Conference Paper: The Respira project: Difference in levels of indoor biological pollutants in schools and homes in Southern Sicily and Malta[Show abstract] [Hide abstract]
ABSTRACT: The Respira project: Difference in levels of indoor biological pollutants in schools and homes in Southern Sicily and Malta Valeria Longo1, David Bilocca2, Chris Zammit2, Martin Balzan2, Fabio Cibella1, Steve Montefort2, Giovanni Viegi1 and Paolo Colombo1 + Author Affiliations 1Istituto di Biomedicina ed Immunologia Molecolare, Consiglio Nazionale delle Ricerche, Palermo, Italy 2Department of Medicine, Mater Dei Hospital, Msida, Malta Abstract Guidelines in asthma and allergic disease highlighted the importance of indoor levels of allergens and LPS evaluation, to identify the "threshold value" in sensitization and symptom onset. The RESPIRA Project has provided a monitoring study of LPS and four allergens (Derp1, Feld1, Alta1 and Phlp5) in Sicily and Malta. Methods: Dust samples were collected by vacuum sampling from schools (12 in Sicily and 6 in Malta – 3 classrooms per each school). From a population sample of 2,047 schoolchildren (11-14 years) a subsample of subjects with and without symptoms of allergic diseases was selected and their houses evaluated (74 in Sicily and 81 in Malta). LPS evaluation was determined by chromogenic LAL assay and allergen quantization was performed by Elisa assays. Results: In Sicily (Health District of Gela), data show a higher level of LPS in schools than in houses (p<0.0001); 70% of houses have a concentration of Der p 1 above the threshold value of sensitization (≥1 µg allergen/g dust) and, in any case, higher in dwellings than in schools (p<0.0001). In Malta no statistical difference in LPS concentration was recorded between houses and schools; on the other hand Der p 1 and Fel d 1 allergens are present in higher amount in Maltese dwelling. No differences were reported for Alt a 1 and Phl p 5. Finally, the comparison between LPS and allergens distribution between Sicily and Malta shows i) a significant higher LPS concentration in Italian schools (p<0.0001); ii) higher Fel d 1 concentration in Maltese schools; iii) higher Der p 1 concentration in Italian houses. Funded by Operational Programme Italia-Malta 2007-2013, RESPIRA Project #A.1.2.3-72.European Respiratory Society Annual congress 2014, Munich; 09/2014
Conference Paper: Indoor and outdoor concentration of PM2.5 vanadium, nickel, and sulphur in three Mediterranean areas[Show abstract] [Hide abstract]
ABSTRACT: Pollutants in particulate matter (PM) are associated with respiratory disorders. Data on indoor concentration of elemental chemical pollutants in highly polluted areas is scanty. In the context of RESPIRA Project, we evaluated both outdoor and indoor concentrations of air pollutants in the Mediterranean area. Gravimetric samples of PM with aerodynamic diameter<2.5 µm were collected on Teflon filters. Concentration of ICP-MS extracted component was measured in 84 sites of South of Sicily (41 in Gela, close to a petrochemical complex, 43 in rural area) and 54 in Malta. Similarly. Indoor measures were performed in 73 houses in Sicily (35 in Gela, 38 in rural area) and in 46 of Malta. Outdoor Vanadium (V) concentrations (median and interquartile range, ng/m3) were: 1.77 (0.60-4.30) in Malta, 1.51 (0.72-2.89) in Gela, and 0.29 (0.11-0.69) in Rural Area (p<.0001); Nickel (Ni): 1.37 (0.65-2.74), 0.82 (0.45-1.37), and 0.29 (0.17-0.55, p<.0001); Sulphur (S) 210 (73-683), 705 (334-1,078), 203 (148-384, p=.0004). Home Indoor V concentrations were 1.34 (0.38-6.70) in Malta, 1.03 (0.44-2.04) in Gela, and 0.16 (0.10-0.44) in Rural Area (p<.0001); Ni: 1.10 (0.52-3.35), 0.61 (0.40-1.16), and 0.28 (0.19-0.35, p<.0001); S: 324 (71-728), 662 (379-1,090), and 257 (187-437, p=.0007). Outdoor/indoor relationships for the investigated elements were tested. V: R2=.665, p<.0001. Ni: R2=.750, p<.0001. S: R2=.587, p<.0001. In conclusion, significantly higher indoor concentration of atmospheric pollutants exist in highly polluted areas. These, in absence of indoor sources, depend on outdoor concentrations RESPIRA Project was funded by Operational Cross-border Program Italy-Malta 2007-2013 code A1.2.3-72.European Respiratory society annual congress 2014, Munich; 09/2014
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ABSTRACT: Low vitamin D is involved in allergic asthma and rhinitis. IL-31 and IL-33 correlate with Th2-associated cytokines in allergic disease. We investigated whether low vitamin D is linked with circulating IL-31 and IL-33 in children with allergic disease of the airways. 25-Hydroxyvitamin D [25(OH) Vit D], IL-31, and IL-33 plasma levels were measured in 28 controls (HC), 11 allergic rhinitis (AR) patients, and 35 allergic asthma with rhinitis (AAR) patients. We found significant lower levels of 25(OH) Vit D in AR and in AAR than in HC. IL-31 and IL-33 plasma levels significantly increased in AAR than HC. IL-31 and IL-33 positively correlated in AR and AAR. 25(OH) Vit D deficient AAR had higher levels of blood eosinophils, exacerbations, disease duration, and total IgE than patients with insufficient or sufficient 25(OH) Vit D. In AAR 25(OH) Vit D levels inversely correlated with total allergen sIgE score and total atopy index. IL-31 and IL-33 did not correlate with 25(OH) Vit D in AR and AAR. In conclusion, low levels of 25(OH) Vit D might represent a risk factor for the development of concomitant asthma and rhinitis in children with allergic disease of the airways independently of IL-31/IL-33 Th2 activity.Mediators of Inflammation 06/2014; 2014(3):520241. DOI:10.1155/2014/520241 · 3.24 Impact Factor
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ABSTRACT: Both severe asthma and obesity are growing health problems. Severe asthma leads to a poor quality of life. The relationship among BMI, comorbidities, and severe asthma control in adults is still unclear. The aim of the study is to better understand the effect of the comorbidities as atopy, type II diabetes, OSAS, gastroesophageal reflux, hypertension, cardiovascular diseases, osteoporosis, infections, and psychological factors with BMI on asthma control in a cohort of adult severe asthmatics. One hundred and two patients were enrolled in a cross-sectional study assessing asthma control, treatments, pulmonary function, inflammatory markers, and comorbidities. Patients were divided into 3 classes according to BMI: normal weight, overweight, and obese. We found that the optimal state of asthma control is lower. whereas the score of Asthma Control Questionnaire, the number of asthma exacerbations during last year, the oral corticosteroids requirement during the previous year, and the LABA treatments are higher in obese than in overweight and normal weight severe asthmatics. The number of subjects with type II diabetes and OSAS are higher among obese and overweight patients than in normal weight asthmatics. In conclusion, BMI represents per se a factor for the deterioration in disease control in severe asthma.BioMed Research International 05/2014; 2014:607192. DOI:10.1155/2014/607192 · 3.17 Impact Factor
Dataset: P-DAG summarizes the possible relationships among variables. Causal effect, between variables, is represented by arrows. The association is represented by segments. The significance of the link is indicated as p-value. The prevalence for each variables is shown.[Show abstract] [Hide abstract]
ABSTRACT: Respiratory allergic symptoms impact on social life and school activities, influencing the patient's mood states. We evaluated the relationships between allergic respiratory diseases and depressive/anxious mood in a large sample of Italian middle school students, using the partial directed acyclic graph (P-DAG). We studied 1283 subjects aged 10-13. A health respiratory questionnaire including questions relevant to socioeconomic status (HCI) and a test for depression and anxiety were administered. All subjects performed spirometry and skin prick tests. A causal role of rhinitis on depression was found: the likelihood of being depressed increased from 11.2 to 17.7%, when rhinitis was present. Moreover, a direct effect of low HCI on depressive mood was shown (p < 0.0001) as well as the correlation between anxiety and depression (p < 0.0001). Gender was not a direct causal factor for depressive mood, but their relation was mediated through anxious mood. Anxiety appeared to have a stronger association with depression than gender. Allergic sensitization was significantly related to both asthma and rhinitis (p < 0.0001, respectively). Asthma and rhinitis were also directly associated (p < 0.0001). Conversely, asthma was not directly associated with depressive mood, but their relation was mediated through rhinitis. Body mass index (BMI) and impaired lung function (IPF) were not associated with the other variables. The use of this novel approach to analyzing the dynamic relationships allowed us to find a causal role of rhinitis on depressive state. Moreover, anxious condition and low socioeconomic status contributed to induce depressive mood.
Article: Rhinitis as a risk factor for depressive mood in pre-adolescents: A new approach to this relationship[Show abstract] [Hide abstract]
ABSTRACT: Respiratory allergic symptoms impact on social life and school activities, influencing the patient's mood states. We evaluated the relationships between allergic respiratory diseases and depressive/anxious mood in a large sample of Italian middle school students, using the partial directed acyclic graph (P-DAG). We studied 1283 subjects aged 10-13. A health respiratory questionnaire including questions relevant to socioeconomic status (HCI) and a test for depression and anxiety were administered. All subjects performed spirometry and skin prick tests. A causal role of rhinitis on depression was found: the likelihood of being depressed increased from 11.2 to 17.7%, when rhinitis was present. Moreover, a direct effect of low HCI on depressive mood was shown (p < 0.0001) as well as the correlation between anxiety and depression (p < 0.0001). Gender was not a direct causal factor for depressive mood, but their relation was mediated through anxious mood. Anxiety appeared to have a stronger association with depression than gender. Allergic sensitization was significantly related to both asthma and rhinitis (p < 0.0001, respectively). Asthma and rhinitis were also directly associated (p < 0.0001). Conversely, asthma was not directly associated with depressive mood, but their relation was mediated through rhinitis. Body mass index (BMI) and impaired lung function (IPF) were not associated with the other variables. The use of this novel approach to analyzing the dynamic relationships allowed us to find a causal role of rhinitis on depressive state. Moreover, anxious condition and low socioeconomic status contributed to induce depressive mood.Pediatric Allergy and Immunology 03/2014; DOI:10.1111/pai.12215 · 3.40 Impact Factor
Conference Paper: Predictive role of mMRC scale on quality of life in COPD patients[Show abstract] [Hide abstract]
ABSTRACT: COPD often coexists with other comorbidities and has an impact on Quality of Life (QoL). We evaluated QoL in COPD patients and the possible role of comorbidities in their relationship. We studied 60 stable COPD outpatients (39 M, aged 53-91) and 30 subjects without respiratory disease (controls, 14 M, aged 50-86). Spirometry and a clinical evaluation of comorbidities were performed. COPD patients were classified on the basis of COPD guidelines. We evaluated dyspnea perception by modified Medical Research Council questionnaire (mMRC). QoL was assessed by SF-36 through Physical Health (PCS) and Mental Health (MCS) components. PCS was significant lower in COPD with respect to controls (p=0.005); no significant difference was found in MCS. mMRC was significant higher in COPD patients (p= 0.022). Among comorbidities (disorders of lipid metabolism -DLM-, hypertension, diabetes, obesity, arrhythmia) only DLM prevalence was significant higher in COPD patients (p=0.012). A significant negative correlation was found between PCS and mMRC (p=0.0001); mMRC was directly related to DLM (p=0.02), only in COPD patients. PCS was not related to comorbidities neither in COPD nor in controls. In COPD PCS was inversely correlated to disease severity according to 2012 guidelines (p=0.001). In conclusion, COPD patients have a poorer QoL with respect to controls in its physical component but not in mental component. Dyspnea perception, in COPD patients is a strong indirect determinant for PCS, regardless of comorbidities. Moreover, among comorbidities DDL seems to determine a higher dyspnea in COPD patients. Detecting and monitoring dyspnea perception may be a useful element in management of COPD patient in order to increase QoL.ERS-Annual Congress 2013 –The latest insights in pulmonary rehabilitation, Barcellona; 11/2013
Conference Paper: Do COPD severity parameters predict mood disorders?[Show abstract] [Hide abstract]
ABSTRACT: We evaluated the mood states disorders in COPD patients and their relationship with COPD severity parameters. We studied 60 consecutive stable COPD outpatients (39 M; aged 53-91) and 30 subjects without respiratory disease (control group) (14 M; aged 50-86). All subjects performed a spirometry and a six minutes walking test (6'WT). Dyspnea perception was evaluated by modified Medical Research Council questionnaire (mMRC). Depressive and anxious symptoms were investigated by Beck Depression Inventory-II and Stay Y, respectively. The COPD patients were classified on the basis of guidelines: 30 in group A, 8 in B, 13 in C, and 9 in D. The prevalence of depressive symptoms in COPD patients and in controls was 28% and 23%, respectively (NS). No significant difference was found between groups for depression severity. Among COPD patients, depressive symptoms distribution was: 5 in categorie A, 4 in B, 2 in C and 6 in D (p=.034). A higher prevalence of depressive symptoms and higher severity levels were found in B+D when compared to A+C subjects (p<0.0001). No difference was found between A+B vs C+D subjects. 6'WT and mMRC were inversely related only in COPD patients (p<0.0001). The mMRC was significant different between groups (p=.022). mMRC and depression were directly correlated (p<0.001). No association was found between depression and GOLD stages, exacerbation in the last year. Anxiety prevalence was not different between groups. Anxiety was not associated with mMRC, GOLD stages, exacerbation in the last year. We conclude that, among individual parameters of COPD severity, only mMRC score is a good, strong and direct predictor of depression in COPD patients. Depressive symptoms should be investigated in COPD when mMRC score is high.Annual Congress 2013 –The best posters in chronic care, Barcellona; 09/2013
- [Show abstract] [Hide abstract]
ABSTRACT: OBJECTIVES: this study aims at presenting the results from the Italian EpiaAir2 Project on the short-term effects of air pollution on adult population (35+ years old) in 25 Italian cities. DESIGN: the short-term effects of air pollution on resident people died in their city were analysed adopting the time series approach. The association between increases in 10 μg/m3 in PM10, PM2.5, NO2 and O3 air concentration and natural, cardiac, cerebrovascular and respiratory mortality was studied. City-specific Poisson models were fitted to estimate the association of daily concentrations of pollutants with daily counts of deaths. The analysis took into account temporal and meteorological factors to control for potential confounding effect. Pooled estimates have been derived from random-effects meta-analysis, evaluating the presence of heterogeneity in the city-specific results. SETTING AND PARTICIPANTS: it was analysed 422,723 deaths in the 25 cities of the project among people aged 35 years or more, resident in each city during the period 2006-2010. MAIN OUTCOMES: daily counts of natural, cardiac, cerebrovascular, and respiratory mortality, obtained from the registries of each city. Demographic information were obtained by record linkage procedure with the civil registry of each city. RESULTS: mean numberofdeaths for natural causes ranged from 513 in Rovigo to 20,959 in Rome. About 25% of deaths are duetocardiac diseases, 10%tocerebrovascular diseases, and 7% to respiratory diseases. It was found an immediate effect of PM10 on natural mortality (0.51%; 95%CI 0.16-0.86; lag 0-1). More relevant and prolonged effects (lag 0-5) have been found for PM2.5 (0.78%; 95%CI 0.12-1.46) and NO2 (1.10%; 95%CI 0.63-1.58). Increases in cardiac mortality are associated with PM10 (0.93%; 95%CI 0.16-1.70) and PM2.5 (1.25%; 95%CI 0.17-2.34), while for respiratory mortality exposure to NO 2 has an important role (1.67%; 95%CI 0.23-3.13; lag 2-5), as well as PM10 (1.41%; 95%CI-0.23;+3.08). Results are strongly homogeneous among cities, except for respiratory mortality. No effect has been found for cerebrovascular mortality and weak evidence of association has been observed between ozone and mortality. CONCLUSIONS: a clear increase in mortality associated to air pollutants was observed. More important are the effects of NO2 (on natural mortality), mostly associated with traffic emissions, and of PM2.5 (on cardiac and respiratory mortality). Nitrogen dioxide shows an independent effect from the particulate matter, as observed in the bi-pollutant models.Epidemiologia e prevenzione 07/2013; 37(4-5):220-229. · 0.78 Impact Factor
Article: Air pollution and urgent hospital admissions in 25 Italian cities: Results from the EpiAir2 project[Show abstract] [Hide abstract]
ABSTRACT: OBJECTIVE: to evaluate the relationship between air pollution and hospital admissions in 25 Italian cities that took part in the EpiAir (Epidemiological surveillance of air pollution effects among Italian cities) project. DESIGN: study of time series with case-crossover methodology, with adjustment for meteorological and time-dependent variables. The association air pollution-hospitalisation was analyzed in each of the 25 cities involved in the study; the overall estimates of effect were obtained subsequently by means of a meta-analy-sis. The pollutants considered were PM10, PM2.5 (in 13 cities only), NO2 and ozone (O3); this last pollutant restricted to the summer season (April-September). SETTING AND PARTICIPANTS: the study has analyzed 2,246,448 urgent hospital admissions for non-accidental diseases in 25 Italian cities during the period 2006-2010; 10 out of 25 cities took part also in the first phase of the project (2001-2005). MAIN OUTCOMEMEASURES: urgent hospital admissions for cardiac, cerebrovascular and respiratory diseases, for all age groups, were considered. The respiratory hospital admissions were analysed also for the 0-14-year subgroup. Percentage increases risk of hospitalization associated with increments of 10 μg/m 3 and interquartile range (IQR) of the concentration of each pollutant were calculated. RESULTS: reported results were related to an increment of 10 μg/m3 of air pollutant. The percent increase for PM10 for cardiac causes was 0.34% at lag 0 (95%CI 0.04-0.63), for respiratory causes 0.75% at lag 0-5 (95%CI 0.25-1.25). For PM2.5, the percent increase for respiratory causes was 1.23% at lag 0-5 (95%CI 0.58-1.88). For NO2, the percent increase for cardiac causes was 0.57%atlag 0 (95%CI 0.13-1.02); 1.29% at lag 0-5 (95%CI 0.52-2.06) for respiratory causes. Ozone (O3) did not turned out to be positively associated neither with cardiac nor with respiratory causes as noted in the previous period (2001-2005). CONCLUSION: the results of the study confirm an association between PM10, PM2.5, and NO2 on hospital admissions among 25 Italian cities. No positive associations for ozone was noted in this period.Epidemiologia e prevenzione 07/2013; 37(4-5):230-241. · 0.78 Impact Factor
Top Journals
Institute of ImmunologySantiago de Cali, Valle del Cauca, Colombia
INO - Istituto Nazionale di OtticaFlorens, Tuscany, Italy
Italian National Research Council
Roma, Latium, Italy
- Institute of Biomedicine and Molecular Immunology "Alberto Monroy" IBIM
Istituto di Bioimmagini e Fisiologia MolecolareSegrate, Lombardy, Italy


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Lightweight, stylish, high performance earbuds give crystal clear sound as well as a comfortable fit. Ideal for use with CD, MP3, MP4 and any other small portable audio players.
33-11605 - Component Video plus L/R Analog Audio to HDMI Converter
Compact converter allows conversion of a component video signal and an analog L/R audio signal to a HDMI 1.2 signal.
35-972 - Full Size Stereo Headphones
High quality headphones feature 40mm diaphragms that deliver full rich sound expected from models at three times the cost. Straight 9' cord has 3.5mm plug and includes 3.5mm to 1/4" adapter. Product is display boxed and is perfect for resale.
50-10145 - Compact 30W Class T Tripath Digital Amplifier
Compact 15W RMS x 2CH Amplifier
Featuring Tripath digital technology, this device provides highly efficient, high quality audio amplification. The extremely small footprint is capable of being powered by eight "AA" batteries, or pick up the Optional 12VDC adapter...
555-17100 - Rack Mount Outlet Strip
Rack Mount Outlet Strip
The GemSound GL99 offers the convenience of a rack-mounted Power control Unit, Providing eight illuminated front switches plus eight rear outlets for your rack-mount power needs.
24-12104 - 25ft 4-pole 3.5mm M-F AV Exten
Designed to work with the 1.5ft 4-pole A/V adapter cables (see 24-9765, 24-9770, 24-9771 and 24-9772), these straight-thru extentions cables range from 1.5ft to 100ft, and feature durable construction, fully molded connectors, and excellect protection against EMI/...
35-4110 - Compact Ported Earbud Headphones with 15mm Drivers and 4' Cord
Compact Ported Earbud Headphones
Lightweight in ear headphones provide terrific audio quality at a budget price. Ported design offers superior low end response.
Very good. Easy to order. Prompt delivery.

subset: commoncrawl


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Pokemon Colosseum
- Genre:
- Strategy
- Release Date:
- 3/22/2004
- Publisher:
- Nintendo
- Gamesite:
- Click Here
By: checkerknights
The title has nothing to do with the video, other than the name Pinky. It's just some clips of Death Wish 3 and Pokemon colosseum put together, to the opening bars of the Nickleback song Next Contestant repeating. Not to be taken seriously it's just one big joke.
Views: 498 | Posted: 05/29/2011
By: YellowSubmarine
Learn how to do the polka with Meow!
Views: 6,789 | Posted: 05/25/2011
By: Walkearth
This is the intro of the Pokemon Snap game for the Nintendo 64.
Views: 1,648 | Posted: 05/25/2011
By: checkerknights
May and Manaphy video to the Pablo Montero song que voy a hacer sin ti
Views: 3,473 | Posted: 04/05/2011
By: Greek117
DontFearTheReaper1 is my youtube channel. I have a roosterteeth account, but since I'm not a sponsor on that sight, I can't post videos on there. "Late Goodbye" - Poets of the Fall "Vampires theme" - Texas Toad Lickers
Views: 327 | Posted: 08/31/2009
By: CS3Tutorials001
Hey guys i played Pokemon Colosseum one weekend and i go to the 100th battle in the Battle tower and i decided to record it.
Views: 1,799 | Posted: 09/29/2008
Views: 13,647 | Posted: 12/08/2004
Views: 10,701 | Posted: 12/08/2004
Views: 8,373 | Posted: 12/08/2004
Views: 6,437 | Posted: 12/08/2004
The classic game of world domination has been invaded by the world of Nintendo....


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Business Therapy for a fraction of the cost
Download a 20-minute K-Talk and get the information you need to handle office politics, manage crazy-making co-workers, and feel less stress at work!
Welcome to K Squared Enterprises!
Click to listen on iTunes!
Hire K Squared to help you advance your career and improve your relationships at work.
Need support as a leader in your company? K Squared executive coaching services can help you win promotions, deal with office politics, and build skills as a leader.
Wondering how to improve your current job and home life? K Squared career & life coaching can assist you in uncovering and pursuing your true goals.
Having trouble with a business partnership? K Squared mediation services can facilitate the resolution of conflict between partners.
Searching for expert speakers? Kathi and Katherine deliver informative and entertaining speeches, lectures and workshops about the real skills needed to succeed at work.
By Logan Medrano
Kathi and Katherine discuss how to break out of the roles we assume at work on this episode of the My ….
Kathi and Katherine discuss people and their personalities in the workplace on this episode of the My Crazy Office podcast. First we give advice to an ….
Kathi and Katherine discuss sex and politics in the workplace on this episode of the My Crazy Office podcast. First we give ….


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A fascinating Wooten roll top walnut rotary desk is one of the more than 400 eclectic lots featured in Schwenke Auctioneers' Fine Estates Auction, set for April 26.
Grandfather Clocks
Uncommon regulator clock strikes a new record: $356,950
Claiming top lot during Fontaine's Auction Gallery's November clock and watch auction was an E. Howard & Company No. 47 wall-hanging astronomical regulator clock – one of only three examples known. The soared to a record price of $356,950.
500+ antique and collector clocks sure to be worth bidders' time Nov. 22-23
Fontaine's gallery will be filled to the brim with clocks, watches and fobs and chains, including a seldom-seen Seth Thomas No. 8 office calendar clock, during the two-day sale Nov. 22-23.
Fall online estates auction offers 17 marble-top tables
Tim's Auctions is holding an online-only estates auction totaling more than 500 lots in a wide array of antiques categories will be held on Sunday, Nov. 17.
Charles Lindbergh memorabilia collection opens fall antique auction
Cordier Auctions is opening its two-day Fall Antique & Fine Art auction with a single-consignor, 80-lot collection of Charles Lindbergh memorabilia.
Florida estates auction offering 25 Lalique examples
More than 350 fresh-to-the-market items of interest to antiques and collectibles aficionados will be sold Nov. 2 beginning at 11 a.m. (EST) in a Florida estates auction hosted by Matheson's Auctions.
Civil War cannon and drum rank high in historic auction bill
A battlefield cannon and drum from the Battle of Gettysburg, plus other Civil War items, will be sold alongside antiques from the historic Dancy-Polk House Inn, in historic auction Oct. 12.
Sale of Anne E. Lisette Boysen paintings funding scholarships
More than 200 large-scale, vibrant and exuberant paintings by the late Philadelphia artist Anne E. Lisette Boysen will be sold in Session II of a two-session auction planned for Saturday, Nov. 10, by Gordon S. Converse & Co.
Philadelphia tall case clock may prompt bidding up to $40,000
Seldom-offered antiquities, fine art, rare documents and fine antiques are crossing the block at Thomaston Place Auction Galleries' three-day sale Nov. 3-5. A seldom-seen selection of ancient pottery from
NAWCC antique watch collectors holding inaugural public day
For the first time ever, the Mid-South Regional meeting organizers will be offering a Public Day to non-members of the National Association of Watch & Clock Collectors. The public can participate in all the functions offered on Saturday, Sept. 1, including the MART and special exhibit, "The Great Antique Clocks of the 1800s."


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Most Popular in:
New in Announcements (page 52 of 136)
Jul 29, 2013 | 09:29 AM CDT
Inter Parfums Lands Deal with Agent Provocateur
nter Parfums plans to launch its first fragrance under the Agent Provocateur brand featuring iconic packaging in 2014, and it will take over distribution of selected fragrances within the brand's perfume portfolio and plans to revitalize the Agent Provocateur signature scent.
Jul 29, 2013 | 09:14 AM CDT
Kardashian Beauty to Launch in Australia, New Zealand
The beauty brand from the Boldface Group and the Kardashian sisters has made a deal with Australian distributor Cosmetics Cubed.
Jul 26, 2013 | 10:10 AM CDT
New CEO Steps In at AmazingCosmetics
Formerly of Kraft Foods, Nancy Sawle-Knobloch joins the beauty brand in a leadership role.
Jul 25, 2013 | 04:35 PM CDT
LVMH Posts 6% Growth for First Half 2013 Revenue
The luxury goods company continued to experience good momentum in the U.S. and Asia, and continues to grow in Europe in a more difficult economic environment.
Jul 25, 2013 | 11:18 AM CDT
Unilever Releases Q2, First Half 2013 Financials
The company's personal care division's growth helps Unilever gain ground in global markets.
Jul 25, 2013 | 11:06 AM CDT
Mexican Beauty Daniela de Jesus Named New Maybelline Spokeswoman
de Jesus will make her Maybelline New York debut in print and television advertising campaigns in late 2013.
Jul 25, 2013 | 11:02 AM CDT
Next Generation Awards from L'Oréal Women in Digital Highlight Forward-looking Technology
At an awards ceremony hosted by actress Olivia Munn, the L'Oréal USA Women in Digital program recognized innovation by women in the tech and beauty worlds.
Jul 24, 2013 | 01:15 PM CDT
Pretty Partners: CEW and Birchbox Team Up
Winners from CEW's 2013 Beauty Insiders' Choice Awards are being promoted in special limited edition Birchbox boxes.
Jul 24, 2013 | 10:58 AM CDT
Inter Parfums Raises Guidance After Financial Report for Three Months Ended June 30, 2013
Based upon the strong first half performance of its ongoing brands and expectations for the remainder of the year, Inter Parfums is raising its 2013 guidance and currently expects net sales to reach approximately $525 million.
Jul 24, 2013 | 09:59 AM CDT
Shakira New Global Ambassador for Crest 3D White Oral Care
Shakira's smile will soon be a feature for P&G's Crest 3D White oral care brand, beginning in fall 2013.


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|Everything you can imagine is real.
– Pablo PicassoRate it:
|Everything you do or say is public relations.
– UnknownRate it:
|Everything you do, do for happiness, you will find that you are a great success.
– Debasish Mridha, M.D.Rate it:
|Everything you see I owe to spaghetti.
– Sophia LorenRate it:
|Everything you want in your future is already in your present.
– Vikrant ParsaiRate it:
|Everything you will ever need to go after/accomplish/fulfill your goal/dream/vision or any other target/aspiration which you will ever set/aspire for is already sitting/waiting patiently inside you. Oh! Yes, all you've got to do is just to take a leap/step of faith forward/towards your goal/target/dream/vision/aspiration and then, sit back and watch it materialize/come true gradually/sooner or later.
– Emeasoba GeorgeRate it:
|Everything you've learned in school as obvious becomes less and less obvious as you begin to study the universe. For example, there are no solids in the universe. There's not even a suggestion of a solid. There are no absolute continuums. There are no surfaces. There are no straight lines.
– Richard Buckminster FullerRate it:
|Everytime you smile at someone, it is an action of love, a gift to that person, a beautiful thing.
– Mother TheresaRate it:
|Everywhere I go I find a poet has been there before me.
– Sigmund FreudRate it:
|Everywhere I go I'm asked if I think the university stifles writers. My opinion is that they don't stifle enough of them.
– Flannery O'ConnorRate it:
|Everywhere is nowhere. When a person spends all his time in foreign travel, he ends by having many acquaintances, but no friends.
– Lucius Annaeus SenecaRate it:
|Everywhere is walking distance if you have the time.
– Steven WrightRate it:
|Everywhere man is in disguise! Who is who is unknown! Try to enter the mask and find out who the man inside really is!
– Mehmet Murat ildanRate it:
|Everywhere we see shadowy minds, cloudy brains! World needs more light of wisdom!
– Mehmet Murat ildanRate it:
|Evgeni Kostitsyn doesn't go to church here in America because he's "afraid to be molested".
– Evgeni KostitsynRate it:
|Evidence-based practice requires no evidence when what it refers to is practice based on guidelines in which the quality of the evidence is based, and in which level E is solely expert opinion.
– David SeresRate it:
|Evil being the root of mystery, pain is the root of knowledge.
– Simone WeilRate it:
|Evil deeds do not prosper the slow man catches up with the swift.
– HomerRate it:
|Evil deeds do not prosper; the slow man catches up with the swift.
– Homer, The OdysseyRate it:
|Evil draws men together.
– AristotleRate it:
|Evil is a fact not to be explained away, but to be accepted and accepted not to be endured, but to be conquered. It is a challenge neither to our reason nor to our patience, but to our courage.
– John Andrew HolmesRate it:
|Evil is a point of view. God kills indiscriminately and so shall we. For no creatures under God are as we are, none so like him as ourselves.
– Anne Rice, Interview with a VampireRate it:
|Evil is always possible. Goodness is a difficulty.
– Anne RiceRate it:
|Evil is done without effort, naturally, it is the working of fate; good is always the product of an art.
– Charles BaudelaireRate it:
|Evil is easy, and has infinite forms.
– Blaise PascalRate it:


text:
VOY: Children of the Storm by Kirsten Beyer Review Thread (Spoilers!)
View Single Post
June 13 2011, 03:50 PM
Re: Star Trek: Voyager: Children Of The Storm Review Thread
I wonder if those Janeway fans who refuse to read anything set after Janeway's death have ever experienced a personal loss in their own lives. If they had, maybe they'd appreciate that it's possible to pay honor and tribute to someone even after they're gone, that they can still be a part of your life even if they aren't physically there. Maybe they'd understand that the grief and anger can't last forever, that loss is something that must eventually be accepted and coped with and integrated into your life as you move on. Janeway is a pervasive, influential presence throughout
Children of the Storm
. The books serve her character very well even though she isn't in them as a living person. I think these Janeway fans would appreciate the books if they allowed themselves to read them.
Written Worlds
-- Christopher L. Bennett's blog and webpage
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text:
Serving the Eugene, Oregon, community for more than 100 years,
EWEB is your customer-owned, not-for-profit water and electric utility. Learn
more about us.
You can start or stop your residential service anytime using our convenient online system.
Lock in a specific date up to 90 days in advance to save money, cut down on wait times and help avoid hassle.
Fall is a popular time to plant trees and shrubs. When selecting a new tree to plant, EWEB recommends the
"Right Tree, Right Place" approach. Proper species selection can increase public safety and reduce power outages.
For your safety, please never attempt to prune or remove trees near electrical lines, call EWEB at (541) 685-7000.


text:
On 30th July, the National Theatre launched its ground-breaking new application National Theatre Backstage at Adobe's launch of its totally re-imagined Adobe Digital Publishing Solution (DPS) in New York.
This new initiative will provide significantly enhanced functionality, usability and creativity compared to the National Theatre's current application, while also opening up new revenue streams, and will run on smartphones and tablets across iOS, with Android release to follow shortly.
iStock by Getty Images partners with Dropbox to make premium creative content accessible anytime, anywhere
Industry-leading integration provides customers with instant, seamless access to their iStock files across all devices [more…]
Rightster, the leading global multi-platform network for online video, has launched an innovative social influencer campaign across multiple territories in APAC, South America and Europe in partnership with Universal Pictures International. [more…]
TugLife has been running this week in line with London Technology Week, discussing the future of digital marketing and the effect the ever growing digital world is having on the human body.
Organised by digital media agency Tug, speakers including Twitter, Google, YouTube and Microsoft have come together at Old Street Roundabout to give advice and share research, which aims to show marketers how they can out-perform competitors and better their campaigns through insight. [more…]


text:
In C, it's not an error to cast pointers to and from
void *.
A major obstacle in porting to C++ is the need to cast pointers when returning from functions dealing with generic pointers such as
malloc, and functions declared in my own code such as
void *block_get(Blkno const blkno);.
My code however is intended to be compiled by C and C++ compilers successfully. If I provide explicit casts everywhere for the sake of C++, they must be C-style casts and I may be masking bugs due to casting non-pointer types to and from pointer types from both languages.
My reference error is the following:
struct Cpfs *cpfs = calloc(1, sizeof(*cpfs));
which in MSVC produces:
Error 2 error C2440: 'initializing' : cannot convert from 'void *' to 'Cpfs *' e:\src\cpfs\cpfs.c 179
Evidently I can't use
new or
static_cast which I'd naturally use if I was no longer using C. What's the best way to provide maximum type safety surrounding
void *for each language with minimal verbosity?


text:
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Product Information:
This is a carbon steel wok from Taylor & Ng. This Classic Wok was designed with a flat bottom to accomodate gas or electric cooktops. This 3-piece wok set includes a single handle flat bottom wok, wood knob dome wok cover to help retain heat while cooking, 1-pair bamboo cooking chopsticks and a wok care/recipe booklet. Any type of cooking utensil can be used on wok.3 Piece Wok Set Includes: Single handle wokDome coverPair of chopsticksWok care/recipe booklet
Special Offer:
12 Issues of Golf Magazine
Included with purchase ($20 value).
Weights & Dimensions
|Product Type: Wok set
|Color: Silver
|Primary Material: Carbon steel
Handles Included: Yes
|Lid Included: Yes
|Non-Stick: No
|Hard-Anodized: Yes
|Enameled: Yes
|Induction Safe: No
|Commercial Use: Yes
|Country of Manufacture: Taiwan, Province of China
|Assembly Required: Yes
About the ManufacturerTaylor & Ng is a 37 years old San Francisco-based business which manufactures, wholesales and retails. The company brings products to market that are sensible and pleasurable in purpose, honest and basic in design, and products whose materials are in as natural a state as practical.
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Does the job Dustin from Marinette, Wi on 04/09/2015 – Verified Buyer
If you clean it with an abrazive it will rust rust rust rust. you have to clean it then wipe some cooking oil into it to keep it from becoming a rusty pile. it rusts absurdly quickly Pros: does the job, cheap Cons: rusts very easy
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wok rebecca from carmel, IN on 01/01/2012 – Verified Buyer
Husband loved it!
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A very good wok Rahm from Rochester, NY on 10/31/2010 – Verified Buyer
It takes a little bit of effort to clean it
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Loved it! Deb from NJ on 06/30/2010
From placing the order, to receiving this item, to using it, I could not be any happier! Excellent product and would HIGHLY recommend it.
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Impressive Author from California on 06/03/2011
I love this wok. I've been searching for a good steel wok (aluminium is so toxic) -- and this one fits the bill. I found it easiest to get off the oil that comes on the product by following the instructions, but when that didn't work completely, I took some stainless steel wool to it. It was magical. Great product.
Was this helpful? Yes 1 No 0


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Schaeffler Will Keep Koerfer on Conti Board, Sueddeutsche Says
Aug. 3 (Bloomberg) -- The Schaeffler Group refused to remove Hans Rolf Koerfer, a member of Continental AG's supervisory board who is accused of having a conflict of interest, from his post, Sueddeutsche Zeitung reported, citing Schaeffler Chief Executive Officer Juergen Geissinger.
Koerfer is the legal adviser to the Schaeffler family, which owns the Schaeffler Group and 42.2 percent of Continental; another 33 percent of Continental is held by banks for the Schaefflers, according to the newspaper.
To contact the reporter on this story: Alex Webb in Frankfurt on firstname.lastname@example.com
To contact the editor responsible for this story: Angela Cullen at email@example.com


text:
Lisa R. FischerJuly 22,2013Lisa R. Fischer
Lisa R. Fischer, 51, of Rutland, died July 17, 2013, at Fletcher Allen Health Care in Burlington.
Memorial contributions, in lieu of flowers, may be made to Rutland County Humane Society, 765 Stevens Road, Pittsford, VT 05763.
A full obituary will be published in a future edition of the Rutland Herald.
Arrangements are under the direction of the Clifford Funeral Home.MORE IN Obituaries
Myrtle A. Greene
WELLS — Myrtle A. Greene, 99, died Oct. Full Story
Marvin W. Chartier
SOUTH LONDONDERRY, VT — Marvin W. Full Story
Ruth M. Rawlins
WYE MOUNTAIN, Ark. Full Story
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Just Do It
One of my absolutely favorite things about the world of cuisine is the experience. There is nothing more breathtaking than overcoming your fears to try something new and different. My personal belief is that I will try everything once. I do indeed mean everything. I've tried many "exotic" foods before on whims because even I have to resist the urge to try scorpion tail.
One time, in my travels in New York City, I was walking through Chinatown when a man selling fresh fish offered me to try some baby octopus. I told him I was researching new foods and cuisines so he was more than happy to oblige my culinary misadventures. The only advice he gave me was to chew fast and swallow. I didn't understand at the time, that was until I saw the plate. They were alive! The little jelly-like aliens were squirming all over the plate he presented to me, writhing around in what looked like some sort of pink fish sauce. Mustering all my courage, I grabbed it with my hand and threw it into my mouth, chewing voraciously like I was told. As much as I chewed, this little critter didn't want to go down. Our battle ensued, I chewed and chewed, and when I finally swallowed, the entire way down I felt every sucker on its legs try to push its way back up my throat. My face was covered in sweat, as it finally rested in my stomach. The toughest meal I've every had but well worth the adventure. Now I love squid and octopus in all forms.
Another time, at the CIA campus in Hyde Park, NY, I was lucky enough to try blood sausage for the first time. Most people find blood disgusting, the thought of even eating a sausage made of blood nauseates them. I, however, love eating meat rare. Meat has its most flavor when served rare, and on occasion I have even eaten steaks blue rare, or barely cooked. when I was offered the option of blood sausage, I jumped at the opportunity. It was like nothing I have ever tasted before. Its rich texture, the feeling of umami on my tongue, it was just exquisite. My take on food isn't for everyone, but for those of you willing to do a little bit of adventuring in your lives, don't think about the taboo or your reasons for not eating it. Instead, just do it.
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- Alumni have appeared in reality competition shows such as Top Chef and Project Runway.
- Has a team of about 4,000 faculty members focused on helping students tap opportunities in a marketplace driven by ideas.
- Offers programs in design, media arts, fashion, and culinary.
- Provides program coordinators who work with students to ensure they have the learning materials, assignments, facilities, and faculty to get the most out of the program.
- Over 50 campus locations nationwide.
- Flexible Scheduling
- Financial Aid
- Transferable Credits
- Its first location, in Paris, officially opened its doors as a culinary school in 1895.
- Teaches students by having them spend significant time in the kitchen practicing precision techniques.
- Provide hands-on training from instructors who are certified, master chefs.
- Offer flexible schedules and online programs.
- Has 30 schools worldwide, spanning 5 continents, including 17 campuses in the U.S.
- Online Courses
- Flexible Scheduling
- Financial Aid
- A part of the Select Education Group (SEG).
- Offers several scholarship and financial aid opportunities for students who qualify.
- California campuses accredited by the Accrediting Commission of Career Schools and Colleges (ACCSC), and accreditation for the Salem campus from the Accrediting Council for Continuing Education and Training (ACCET).
- 4 Campuses located in Clovis, Modesto, and Redding in California, and Salem, Oregon.
- Accredited
- Flexible Scheduling
- Financial Aid
- Transferable Credits
- Provides students the opportunity to train at home in their spare time to get their high school diploma, train for a new career, or enhance current skills.
- Offers programs in psychology/social work, business management, medical billing, criminal justice, and more.
- Member of the United States Distance Learning Association (USDLA), the Canadian Network for Innovation in Education (CNIE), and the International Council for Open and Distance Education (ICDE).
- Features a fully flexible schedule with no classes to attend, leaving the study pace up to the student.
- Online Courses


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IMDb > Mr. White (Character)
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Filmographiesby yearby typeby ratingsby votesby TV seriesby genreby keyword
Did You Know?photo galleryquotes
Mr. White (Character)
from Reservoir Dogs (1992)
The content of this page was created by users. It has not been screened or verified by IMDb staff.
|Photos (See all 4 | slideshow)
|Related Videos (see all 5)
There may be more photos available for this character. To select more photos to be displayed in this character's gallery, click the Edit Photos link.
Larry Dimmick, AKA Mr. White was involved in a diamond heist with five other men... See more »
FilmographyEdit Credits
There may be more credits available for this character. To edit the credits displayed or to add more credits to this character's filmography, click the Edit Credits link.
Jump to filmography: Video-game, Archive Footage
- Reservoir Wolves (2001) Played by David Ellington
- Reservoir Guide Dogs (1995) Played by Nity Raj
- Reservoir Dogs (1992) Played by Harvey Keitel
- Reservoir Dogs (2006) (VG) Played by Jack McGee
Archive Footage:
- "Special Collector's Edition"
... aka "Edición Especial Coleccionista" - Spain (original title)
- Especial redoblajes (2011) TV episode, Played by Harvey Keitel
- Who Do You Think You're Fooling? (1994) Played by Harvey Keitel / Danny Lee
Additional Details
Plot Keywords:
Blood / Blood Splatter / Chase / Controversy See more »
Fun Stuff
From Reservoir Dogs (1992)
Mr. White: If you shoot this man, you die next. Repeat. If you shoot this man, you die next. See more »
Mr. White: If you shoot this man, you die next. Repeat. If you shoot this man, you die next. See more »
You may correct errors and omissions on this page directly. Clicking the 'Update' button will take you through a step-by-step process.


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The Skatalites' Lloyd Brevett Dies at 80
A recent report from the Jamaica Observer newspaper found close friend and former Columbia Records A&R person Maxine Stowe explaining that Brevett's health had deteriorated considerably in recent months following the fatal February 26 shooting of his son Okeene near Brevett's home in the Seaview Gardens area of St. Andrew. Okeene was returning home after accepting an award on his father's behalf from the Jamaican recording Industry Association.
Brevett helped found the original lineup of the Skatalites in 1963, and the ten-person roster stayed together for 18 months. While they acted as a backup band on several pioneering ska recordings, the group also recorded a number of notable instrumentals on their own, including "Guns of Navarone" and "Eastern Standard Time."
Beyond his tenure as the group's upright bassist, Brevett also produced two Skatalites albums, 1975's African Roots and 1976's The Legendary Skatalites. The musician was honoured several times throughout his career, having been bestowed Jamaica's Order of Distinction in October 2001 and the Silver Musgrave Medal for his contribution to music in October 2010.
The news of Brevett's passing comes just shy of a year after drummer Lloyd Knibb died, also at the age of 80.
While the Skatalites still exist in an altered line up, Brevett's passing leaves saxophonist Lester Sterling the only surviving member of the original group.
Brevett is survived by his wife Ruth.
Coming back soon! If our developer were more machine than man they'd already be here. Useless meatsack.
For now, please send any and all feedback to [email protected].
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35 years of experience
Accepting new patients
35 years of experience
Accepting new patients
Saint Charles
2747 W Clay St
Saint Charles, MO 63301 Phone number & directions
2747 W Clay St
Saint Charles, MO 63301 Phone number & directions
License & Identifications
A medical license is required for a doctor to practice medicine in a particular state. Requirements vary by state but most require, at a minimum, post-graduate training in the doctor's specific specialty. An NPI number is a national identifier unique to an individual health care provider and is managed by the Center for Medicare & Medicaid Services (CMS).
Learn more about Dr. James Faber:
View the full profile to get information on:
- Qualifications
- What's important to you
View full profile
Patient Reviews
Patient comments (0)
The overall average patient rating of Dr. James Faber is Excellent.
Education & Awards
Dr. Faber graduated from Baylor College of Medicine, Houston.
Home > Find a Dentist > MO > Saint Charles Dentists > Dr. James Faber, DDS, DMD
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- Additional Information
- Dr. James Alvin Faber DDS and DMD is a male dentist, has 35 years of experience and practices in Family Dentistry.
- Where does Dr. James A. Faber practice?
- Dr. James Faber has 1 office location.
Dr. James Faber practices Family Dentistry near Saint Charles, MO.
See Saint Charles Dentists.


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Starred Review. Like the 44 million other Americans caring for an ill or elderly person in their homes, prolific writer Sheehy looked after her late husband Clay Felker while he battled cancer for more than a decade. Having already chronicled almost every stage in baby boomer life (most notably in 1976's Passages), Sheehy offers an empathetic, well-researched guide to an unfamiliar, often scary role to which boomers are being initiated, outlining eight stages of caregiving from "Shock and Mobilization" to "The Long Good-Bye." Along with doctors and nurses, home caregivers have become the backbone of the (admittedly broken) U.S. health-care system, and an increasingly important part of a patient's decision-making team. As such, Sheehy contends, caregivers are in desperate need of knowledge and support, and this resourceful manifesto provides it, including practical steps to take, strategies for each point of care, likely obstacles for both patient and caregiver, and a lucid explanation of what's to come: "My intention is to illuminate the challenges and rewards inherent in the caregiving passage-to identify universal patterns in the chaos and give the journey a form that makes sense." Sheehy achieves her goal ably, providing a steady beacon during a time of great sadness and overwhelming responsibility.
Thrust into the daunting and unexpected role of caregiver when her husband, editor Clay Felker, was diagnosed with cancer, Sheehy was dismayed to find herself lost in the labyrinthine, illogical, and often contradictory world of health care. When second opinions gave way to thirds, and innumerable insurance forms were completed only to have the claims rejected, Sheehy realized she needed answers, assistance, and attitude. For a tenacious reporter like Sheehy, getting answers was second nature but finding competent help and learning how to put things into perspective weren't as easy. Sheehy reports on her interviews with professionals in traditional and alternative medicine, registered nurses and home health aides, and diverse individuals who also found themselves overwhelmed by caring for an ailing loved one, and she distills the process into eight stages, from the shock of the first diagnosis to the delicacy of saying good-bye, bringing her inimitable, analytical approach to a situation no one wants to face. Supportive and reassuring, Sheehy provides encouraging and practical information for both patient and caregiver in one of the most comprehensive and trustworthy resources a family can ask for when facing one of life's most disheartening challenges. --Carol HaggasSee all Editorial Reviews
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The name of this book is a misnomer. It should be "Passages in Caregiving for the Rich and Famous". Ms. Read morePublished 2 days ago by becky miltenberger
Anyone who knows someone or who is in a position of caregiving should read this book.....it is excellent.....it is so much more than just her experience.... Read morePublished 1 month ago by Amazon Customer
Sheehy is an author I have long adored. She went above and beyond in this book, giving me everything I wanted and needed and more.Published 1 month ago by James Sherman
Great and practical suggestions with the appropriate contact information, which makes it very useful. Read morePublished 1 month ago by Senior Sally
This was helpful when I was caring for my Mother. It was good to hear from someone who was facing the same stresses and concerns.Published 2 months ago by League City Sue
This book is very well written and includes a lot of resources. The ONLY reason I did not give it a 5 star rating is because I feel the author fails to take into account those... Read morePublished 3 months ago by Lori D'Amico
Although I'm sure the content would be helpful to some, it's very long, and as a caregiver, I just don't have the time to read through it all.Published 3 months ago by CJH
Not as good as her other books, but she does her homework and writes beautifully.Published 4 months ago by Amazon Customer


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Welcome to Home Rec Gameroom & Leisure. We offer quality products for homeowners and businesses in Metro ... more
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beyond doubt, the best dental experience ever. I used to be really afraid of dentists, but Dr. Kim was s... more
© 2015 Local Corporation - US Patent 7,231,405
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ARE YOU KIDDING ME?! Voyager Ep Counterpoint (Season 5)
View Single Post
July 29 2013, 02:19 PM
Defiant Obrien
Location: Seattle
Re: ARE YOU KIDDING ME?! Voyager Ep Counterpoint (Season 5)
That is my point. Janeway is a COMPLETE prude.. She keeps chakotays balls in a jar for 7 years because he's a pussy. (He's her fallback plan LOL)
She has had ample opportunity to bang tuvok (maybe she has)..
So here comes this alpha male Kashik and she is like "wow who knows when I'll get another chance for a one night stand.. PANTIES ARE DROPPING"
That bullshit about "holding out for mark" and her dear john letter as her closure is just typical chick logic. You notice how she arbitrarily changed her hair style and got more assertive WELL BEFORE THAT (season 4 i believe)
Guy Gardener wrote:
One opportunity?
She could make out with anyone anywhen.
Defiant Obrien
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We are very pleased that Riad Papillon has been selected for inclusion by Chic Retreats the most reliable source for genuinely small boutique and luxury hotels.
Chic retreats members are welcome at Riad Papillon and are asked to please show their membership cards on arrival. With only five rooms and a commitment from all our staff to provide the best possible personal service you will not be dissapointed in your experience at Riad Papillon.
We are very proud of our newly installed Moroccan tent on the Roof Terrace at Riad Papillon. Hand made by local craftsmen it is a beautiful and romantic space especially in the evening when it can be lit by candles.
The tent will feature during the winter months and is an excellent place to eat, whether a wonderful breakfast or a delicious evening meal. Why not book a dinner in advance for the evening of your arrival?


text: A very wide ranging menu with many specialities based on the heat of the dish as well as the usual standards. Portion sizes are better than expected. Generally helpful staff and fairly quick service even when busy. Best to book on Fridays and Saturdays. They do a mid week special that includes... read more


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Outdoor enthusiasts: your adventure is waiting — in 3-D. With topographic map data from the Danish Geodata Agency (GST), this product shows height contours, forest regions, marsh areas, coastal depth curves as well as bathymetric maps for selected lakes in Denmark.
File Information
The file size of this download and space required on device or microSD™/SD™ card is 740 MB. If this download does not fit on your device, data may be saved on a microSD/SD card (recycled microSD cards may be used to program map data).
Use with 1 Device Only
This download only may be used on 1 compatible device. Data downloaded to a microSD/SD card is associated with the device you select during the download process. Please purchase additional quantities for additional devices.
Product Compatibility
Make sure your device is compatible with this product before purchasing. Downloadable products are non-refundable. Some map features will not work on nüvi® devices.
A card reader and microSD/SD card are required to download mapping to the following devices: eTrex® Legend Cx/HCx, Vista Cx/HCx, Venture Cx; GPSMAP® 60CSx/60Cx; GPSMAP 76CSx/76Cx; Rino® 520HCx/530HCx; Astro® 220; StreetPilot® 7200/7500 (not all devices are compatible with all downloads).
Download Times
Not for use with dial-up Internet access or satellite Internet providers. Actual download speeds may vary.
Expiration Date
You have 1 year from the date of purchase to download this file.
Minimum Requirements
The download process requires you to install the free Garmin Communicator Plugin on your computer so we can communicate with your device. Note: The download is installed directly to a device or microSD/SD card and is not accessible on the computer.
Make sure your device is compatible with this product before purchasing.
To view and use the maps on this card, you must have a device with a microSD/SD card slot. Maps on microSD/SD cards cannot be copied or viewed on a computer.
Reduced price map updates are not available for these cards. If you want to update the maps, you must purchase a new card that includes the latest map data.
The microSD/SD card package includes a microSD card and an SD card adapter.
Features detailed digital topographic map coverage of Denmark.
Site Map • Terms of Use • Statement of Privacy • Copyright © 1996-2014 Garmin Ltd. or its subsidiaries


text:
The K of D, an Urban Legend
Michael Rice interviews members of the team responsible for The K of D, an Urban Legend, which opens September 20, 2008 at the Magic Theatre.
One young girl embodies the entire population of her small town to spin the story of the summer that inexplicably changed her life. This quirky and touching play offers the unexpected perspective of a child on the big questions of life and death.
The K of D, an Urban Legend runs through October 19, 2008 at the Magic Theatre. For tickets and information visit magictheatre.org.
Also on KQED.org this week ...
Jacques Pépin Heart & Soul
Jacques Pépin Heart & Soul is chef Jacques Pépin's final television cooking series. Get recipes, view behind-the-scenes photos and more!
"Future of You" Looks at Digital Health and Big Data
Explore how emerging technologies are revolutionizing medicine and how an explosion of information is changing the way we manage our health.


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DEFINITION of 'Canadian Deposit Insurance Corporation - CDIC '
A crown corporation owned by the Canadian government that insures bank deposits up to C$100,000 per personal account held in member Canadian banks in they event that the financial institution fails. The corporation was formed under the Financial Administration Act and Canada Deposit Insurance Corporation Act in 1967. The CDIC is similar to the Federal Deposit Insurance Corporation in the United States.
BREAKING DOWN 'Canadian Deposit Insurance Corporation - CDIC '
Between 1967 and 2008, Canada experience the failure of 43 financial instutions, all of which were CDIC member banks. When using a bank in either in the United States or Canada, FDIC or CDIC membership is important to consider, as it provides depositors with some insurance against losing their savings.
Canadian Competition ActA federal law that governs business practices in Canada. The ...
Risk-Based Deposit InsuranceDeposit insurance with premiums that reflect how prudently banks ...
Ontario Securities Commission - ...The securities regulator that supervises and enforces regulations ...
Crown CorporationAny corporation that is established and regulated by a country's ...
Federal Deposit Insurance Corporation ...The U.S. corporation insuring deposits in the U.S. against bank ...
BankA financial institution licensed as a receiver of deposits. There ...
Are Your Bank Deposits Insured?Learn how the FDIC is helping to keep your money in your pockets.
Mutual Funds & ETFs
Money Market Mutual Funds: A Better Savings AccountAn good alternative to the traditional savings account is the money market mutual fund. It's easy, safe and has better returns.
Home & Auto
Are My Investments Insured Against Loss?Money invested in a brokerage account has some protection, but that doesn't mean you can't lose it.
CDIC Protects Canadians From Bank FailureBank failures can happen in Canada, but many deposits are insured. Find out what's covered.
Explaining Indemnity InsuranceIndemnity insurance is an insurance policy that protects business owners and employees from losses due to failure to deliver expected services.
What is a Force Majeure?A force majeure clause frees both parties in a contract from fulfilling their obligations in the event of some catastrophic or unexpected occurrence.
How Car Insurance Companies Value CarsLearn the methodology used by car insurance companies to value cars, and understand why the amount they give you may not cover the cost of a similar vehicle.
Mutual Funds & ETFs
Mutual Funds Are Not FDIC Insured: Here Is WhyFind out why mutual funds are not insured by the FDIC, including why the FDIC was created and how to minimize your risk with educated mutual fund investments.
The Better Way to Save: Life Insurance or IRA?Sure, you can tap your permanent life insurance policy to help fund your retirement. But in most cases, an IRA is the better choice. Here's why.
How to Help Clients Navigate Open EnrollmentWith companies trying to pass on more costs to employees, making the right choices during open enrollment is more important than ever.
Who decides to print money in Canada?In Canada, new money comes from two places: the Bank of Canada (BOC) and chartered banks such as the Toronto Dominion Bank ... Read Full Answer >>
What is the difference between a peril and a hazard?The two related terms "peril" and "hazard" are often used in reference to the insurance industry. Essentially, a peril is ... Read Full Answer >>
Why are mutual funds not FDIC-insured?Mutual funds are not Federal Deposit Insurance Corporation (FDIC)-insured because money invested in funds are not considered ... Read Full Answer >>
What level of reserve ratios is typical for an insurance company to protect against ...In the United States, and most developed nations, regulators impose required statutory capital reserve ratios on insurance ... Read Full Answer >>
What risks do I face when investing in the insurance sector?Like all equity investments, insurance companies present investors with market risk. Insurance companies, like banks, also ... Read Full Answer >>
Why do insurance policies have deductibles?Insurance policies have deductibles for behavioral and financial reasons. Moral Hazards Deductibles mitigate the behavioral ... Read Full Answer >>


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Hello & Welcome to Schwan Buick GMC Cadillac! Schwan Buick GMC Cadillac is recognized as a proven leader and an instrumental dealership during the reinvention of the new General Motors. As General Motors embraces a new and exciting future, one constant remains the same. Schwan Buick GMC Cadillac offers the best selection of Cadillac, Buick and GMC truck models available. As always, we continue to sell and service our vehicles with enthusiasm and at very competitive prices! Please stop by to look at our selection and enjoy a cup of coffee. We are looking forward to seeing you!
Schwan Buick GMC Cadillac| Bismarck and Mandan Buick Cadillac GMC & Pontiac


text: Just returned from 10 days at The sebastian and it was everything I hoped for. The staff were exceptional both in the hotel itself and the ski valets at 'Base Camp'. The room was spacious and perfectly clean and the daily house keeping services were very good. The breakfast offered a wide and substantial choice setting us up well for a day on the slopes. I have stayed in numerous ski hotels in Europe and the west coast of the USA and overall this was the best hotel and skiing experience. We visited the other local ski resorts that are included in the Vail ski pass and they dont come close to Vail - dont bother trying them !.


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Need a car makeover? You can easily get that by installing your rig with Bushwacker Fender Flares and Bushwacker Parts. Here at JC Whitney, we can provide you with up-to-date Bushwacker products for your accessorizing needs. And what's more? We even have a wide selection of low-priced Bushwacker Car Parts available. So why prolong your waiting when you can get these high-quality components today?
Bushwacker's Trail Armor rocker guards for Jeeps are built tough to ward off road grime, debris and anything else that comes at your... Read more
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So the only time you realize that there's a problem in your ride is right after it hit you square in the face. And this means that it normally takes you quite a while before you spot something unusual with your car. Since this trait is not an ideal trait to begin with, why not practice anticipating the problems before they materialize? Take your rig for example. You know that you're going to use it for off-road driving. And because that kind of activity can take its toll on its appearance, equipping it with various protective accessories is a good idea. And that's exactly what Bushwacker products can do for you.
Bushwacker bumper protectors and Bushwacker rear corner guards–these are some of the components that you can use to protect your ride from the wear and tear that comes with off-road driving. All of them are constructed from heavy-duty materials that can withstand the beating from such outdoor activity. Additionally, these accessories are made for easy mounting. So even if you don't have the cash to hire a mechanic, you can make the installation process yourself. To top it off, most Bushwacker products are available in affordable prices that would surely fit your budget.
Prevention is the main key in solving vehicle problems. And that's where Bushwacker can help you out with its Bushwacker Car Parts. And here at JC Whitney, we have an extensive collection of Bushwacker Fender Flares and Bushwacker Parts that would suit your every need.
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Flats to let in Turnpike Mews, Turnpike Lane, London N8 - 4 bedrooms
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Gladstone Avenue, Wood Green/London N22Maisonette to rent - 4 bedrooms
Spacious 4 bedroom maisonette available end of October in Wood Green More details
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- Wood Green (0.3 miles)
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Marketed by Zone Lettings And Management Ltd, N15. Call 020 3463 2560


text:
Somewhere between the physical and the virtual
System Center Blogs
Configuration ManagerThe team that supports Configuration Manager.
OrchestratorA blog by the teams who make and support Orchestrator.
Operations ManagerThe folks who make and support Operations Manager.
Data Protection ManagerBlog done by the Data Protection Manager product and support teams.
Service ManagerCommunications from the System Center Service Manager team.
Virtual Machine ManagerThe team that makes and supports Virtual Machine Manager.
Related Sites
System Center HomeThe home page for System Center on the Web.
Essentials Wiki
System Center on TechNetTechNet's agglomerated resources on System Center.
myITforum.comRod Trent's Web site primarily focused on systems and configuration management.
SystemCenterCentral.comThird-party site that pulls together stuff across the SC suite.
Deployment ForumCommunity site about Windows deployment matters.
The Blogcast RepositoryWhere you'll find technical videos, blogs, forums and more on Config Manager as well as other System Center products.
FAQShop.comHints, tips, answers, FAQs on Microsoft's systems management products.
Virtualization FeedMaster aggregator of blog posts and twitters on virtualization.
Virtualization HomeFor all pertaining to the Microsoft Virtualization story.
When you combine the last day of a conference with that same day being the 'morning after' that event's main party, it could easily be cause for miss out on some great sessions. Those who did attend the Tools and Best Practices for Management Pack (MP) Authoring session on Friday morning at MMS 2008 were treated to a great demonstration by David Aiken who introduced the newly released Team System Management Model Designer (TSMMD).
TSMDD is a Power Tool for Visual Studio that allows architects to build heath models for .NET applications. Through TSMDD, users can generate code to implement a health model through events and performance counters, use the tool to automatically validate the model, and then generate a fully operational MP - and all without having to see XML!!
Once your MP is created you can then choose to import it directly into your Operations Manager 2007 deployment, or develop it further. Some of the other features provided include:
To learn more about this new Power Tool you can read about it on MSDN, download the Power Tool, as well as see it in action in David's upcoming web seminar scheduled for 10am PT on May 15th.
Another great authoring tool now available is the new System Center Operations Manager Authoring Console, which you can immediately download in either the 32-bit or 64-bit edition. This powerful tool delivers true offline authoring capabilities, without the need to actually interact with any XML, allowing you to:
By now I'm sure you are asking which one you should use. As mentioned, TSMDD is ideally suited for quickly building health models for .NET applications - and I mean really quickly. The Authoring Console provides a lot more 'whistles and bells' for MP development, allowing you to customize and optimize existing MPs, or create a fully functional MP in a much shorter timeframe than writing pure XML. Ultimately I say give both a try and see which works for you. They're available for free download through the links indicated above - and you may find you end up using both!
As you try these out, also keep an eye out on TechNet where we'll be posting more information, including webcasts, on how to use our new authoring solutions to optimal effect.
Happy authoring!
Sacha Dawes Sr. Technical Product Manager System Center
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Product Information:
The 71'' Bullet desk id intended for use with a return or a bridge if applicable in application. The unit extends the work surface and joins the component to create individual work stations. The Cherry and Mahogany laminate is durable yet attractive. The unit can be used in either left or right handed configurations.
Product Details
Weights & Dimensions
|Desk Type: Desk shell
|Top Material: Laminate
|Base Material: Laminate
|Application: Professional office
|Gloss Finish: Yes
|Hardware Material: Stainless Steel
|Non-Toxic: Yes
|Design: Peninsula desk
|Cable Management: Yes
|Keyboard Tray: No
|Height Adjustable: No
|Bow Front: Yes
|Drawers Included: No
|Exterior Shelving: No
|Cabinets Included: No
|Ergonomic Design: No
|Handedness: Both left and right
|Chair Included: No
Legs Included: Yes
|Casters Included: No
|Hutch Included: No
|Treadmill Included: No
|Cork Back Panel: No
|CPU Storage: Yes
|Built In Outlet: No
|Built In Surge Protector: No
|Light Included: No
|Modular: No
|Lifestage: Adult
|Commercial Use: Yes
|Product Care: Wipe clean with a damp cloth
|Country of Manufacture: China
|Weight Capacity: 250 Pounds
|Solid Wood Construction: No
|Assembly Required: Yes
|Tools Needed: Screwdriver
|Additional Parts Required: No
|Product Warranty: Limited 1 year warranty
About the ManufacturerBoss Office Products – a division of Norstar, has always been a major company in the office furniture industry. With headquarters in California and a branch in Atlanta, Boss Office Products has a strong foothold in office products across the nation. The company specializes in the design and manufacturing of all types of office seating products. Some of their most successful products include executive chairs upholstered in various materials, as well as task seating. Ergonomics plays a big role in the development of Boss Office Products and will bring the company into the future with new and improved ways to make office seating comfortable and affordable.
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Ships via: Front Door Drop Off (No Signature Required) w/ Upgrade Options
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We want you to love it. If you don't, you may return your purchase within 30 days of delivery. All you need to do is visit our Self-Service Return Center for instructions. Return credits are issued within 24 hours once the item is received and inspected. Please note that shipping charges are non-refundable. The cost of return shipping will be deducted from your refund. 30-Day Return Policy
Overall Rating
Based on 1 review
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Great Desk Susan from San Antonio, TX on 05/06/2015 – Verified Buyer
We received this desk on time and as described. It works so well in our office we ordered 2.
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