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Chondroitin sulfate-E (chondroitin-4, 6-disulfate) was prepared from chondroitin sulfate-A (chondroitin-4 - sulfate) by regioselective sulfonation, performed using trimethylamine sulfur trioxide in formamide under argon. The structure of semi-synthetic chondroitin sulfate-E was analyzed by PAGE, (1)H NMR, (13)C NMR, 2D NMR and disaccharide analysis and compared with natural chondroitin sulfate-E. Both semi-synthetic and natural chondroitin sulfate-E were each biotinylated and immobilized on BIAcore SA biochips and their interactions with fibroblast growth factors displayed very similar binding kinetics and binding affinities. The current semi-synthesis offers an economical approach for the preparation of the rare chondroitin sulfate-E from the readily available chondroitin sulfate-A.
Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.
This article was published in the following journal.
Name: Carbohydrate polymers
Pages: 822-829
The application of 2,2,2-trichloroethyl sulfate to the synthesis of chondroitin sulfate C and D.
Chondroitin sulfates (CSs) have characteristic bioactivities that depend on sulfation patterns. Chemically synthesized CS oligosaccharides are valuable tools for elucidating the relationship between s...
Discrepancies in Composition and Biological Effects of Different Formulations of Chondroitin Sulfate.
Osteoarthritis is a common, progressive joint disease, and treatments generally aim for symptomatic improvement. However, SYmptomatic Slow-Acting Drugs in Osteoarthritis (SYSADOAs) not only reduce joi...
Chondroitin sulfate effects on neural stem cell differentiation.
We have investigated the role chondroitin sulfate has on cell interactions during neural plate formation in the early chick embryo. Using tissue culture isolates from the prospective neural plate, we ...
Chemical fucosylation of a polysaccharide: a semi-synthetic access to fucosylated chondroitin sulfate.
Chemical O-glycosylation of polysaccharides is an almost unexplored reaction. This is mainly due to the difficulties in derivatizing such complex biomacromolecules in a quantitative manner and with a ...
Diagnosis of Morquio Syndrome in Dried Blood Spots Based on a New MRM-MS Assay.
Mucopolysaccharidosis IVA (MPS IVA; Morquio A disease) is an autosomal recessive disease caused and characterized by a decreased activity of N-acetylgalactosamine-6-sulfate sulfatase (GALNS), resultin...
Efficacy and Safety of Prednisolone and Chloroquine Add on Therapy in Osteoarthritis of the Knee
This study was conducted to evaluate the efficacy and safety of prednisolone and chloroquine add on therapies to combined glucosamine, chondroitin sulfate in osteoarthritis of the knee whi...
Efficacy and Safety Study of Glucosamine/Chondroitin Sulfate to Patients Treatment With Osteoarthrosis of the Knee
The purpose of this study is to assess the efficacy and safety of glucosamine and chondroitin sulfate association in the treatment of patients with osteoarthrosis of the knee.
Absorption and Distribution of Glucosamine and Chondroitin
The purpose of this study is to examine the way the dietary supplements glucosamine and chondroitin are absorbed and distributed throughout the body.
Effect of Chondroitin Sulphate on Synovial Inflammation in Patients With Osteoarthritis of the Knee
The purpose of this study is to determine the effect of a chondroitin sulphate conventional treatment on the degree of severity of synovitis, as measured by magnetic resonance in patients ...
Chondroitin Sulphate Efficay/Safety in Patients With Knee Osteoarthritis and Psoriasis
The purpouse of this study is to determine the efficacy and safety of chondroitin sulphate conventional treatment in patients with both knee osteoarthritis and plaque psoriasis.
Chondroitin Sulfates
Derivatives of chondroitin which have a sulfate moiety esterified to the galactosamine moiety of chondroitin. Chondroitin sulfate A, or chondroitin 4-sulfate, and chondroitin sulfate C, or chondroitin 6-sulfate, have the sulfate esterified in the 4- and 6-positions, respectively. Chondroitin sulfate B (beta heparin; DERMATAN SULFATE) is a misnomer and this compound is not a true chondroitin sulfate.
Chondroitinases And Chondroitin Lyases
Enzymes which catalyze the elimination of glucuronate residues from chondroitin A,B, and C or which catalyze the hydrolysis of sulfate groups of the 2-acetamido-2-deoxy-D-galactose 6-sulfate units of chondroitin sulfate. EC 4.2.2.-.
Chondroitin Lyases
Enzymes which catalyze the elimination of delta-4,5-D-glucuronate residues from polysaccharides containing 1,4-beta-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages thereby bringing about depolymerization. EC 126.96.36.199 acts on chondroitin sulfate A and C as well as on dermatan sulfate and slowly on hyaluronate. EC 188.8.131.52 acts on chondroitin sulfate A and C.
Chondroitin Sulfate Proteoglycans
Proteoglycans consisting of proteins linked to one or more CHONDROITIN SULFATE-containing oligosaccharide chains.
Dermatan Sulfate
A naturally occurring glycosaminoglycan found mostly in the skin and in connective tissue. It differs from CHONDROITIN SULFATE A (see CHONDROITIN SULFATES) by containing IDURONIC ACID in place of glucuronic acid, its epimer, at carbon atom 5. (from Merck, 12th ed)
Biotechnology - Biotech
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"using living things to create products or to do tasks for humans" About Biotechnology - Biotech Biotechnology is the practice of using plants, animals and micro-organisms such as bacteria, as well as biological processes - such as the ripen...
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Interactive Seating Charts
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La Palestre730 av Georges Pompidou
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Morris House Dedication, Ambassador Pickering Lecture Among Fallcoming Highlights - The dedication of Morris House as Hamilton's newest residence hall and a lecture by career diplomat Thomas Pickering about the status of Iran will be among Fallcoming Weekend highlights on Oct. 1-4.
hyphens, compound modifiers
As a general rule, compound modifiers are hyphenated before the noun but not after the noun: "The team scored in the first quarter." "The team scored a first-quarter goal." However, when a modifier that would be hyphenated before a noun comes after a form of the verb "to be," the hyphen is usually retained: "The scholar is well-known." "The child was soft-spoken." Two words that are commonly associated do not require a hyphen: the real estate agent, the health care system. Compounds that end in "ly" are not hyphenated: the newly appointed dean, the nationally ranked hockey team.
SOURCE: Hamilton College Editorial Style Guide


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Top-ranked, top-seeded Florida faces a 20th-ranked and fourth-seeded UCLA team that boasts maybe the most explosive offense in the country. The winner of Thursday night's Sweet 16 matchup in Memphis plays Saturday for a ticket to the Final Four.
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Icahn Seeks to Stop Lions Gate Director Voting Shares
Nov. 9 (Bloomberg) -- Carl Icahn, who has made a hostile bid for Lions Gate Entertainment Corp., told a judge through his lawyer he will seek to block board member Mark Rachesky from voting his shares at the studio's Dec. 14 annual meeting.
Icahn, the billionaire chairman of New York-based Icahn Enterprises LP, will file the motion to suspend Rachesky's voting power in New York state Supreme Court Nov. 15, attorney Joseph DiBenedetto told Justice James Yates today.
Icahn, 74, who is attempting to buy the independent film and TV studio for $7.50 a share, sued Vancouver-based Lions Gate in both Canada and New York in July to reverse an equity-for-debt swap that increased Rachesky's stake to almost 29 percent. Icahn argues that management conspired with large shareholders to thwart his bid.
The Supreme Court of British Columbia on Nov. 1 dismissed the Canadian suit by Icahn to undo the deal. Icahn has appealed. An appeals judge on Nov. 5 denied his request for an expedited hearing. Lions Gate told the New York judge today the Canadian ruling supports its motion to dismiss the New York case and said there is no reasonable basis for a court order against Rachesky.
"This court cannot rule in the Icahn Group's favor without holding that the British Columbia court got it wrong," Lions Gate attorney William Savitt wrote in a letter today to Yates. "This is precisely the situation that this court wished to avoid when it noted at the September 17 conference that it 'would drop this case like a hot potato' in the event the British Columbia court issued a clear ruling."
Canadian Ruling
Savitt's letter responded to a Nov. 8 letter from DiBenedetto to Yates that said the Canadian ruling didn't resolve the legal dispute in New York and that the "entire contract issue remains ripe for decision by this court."
In July, Lions Gate issued new shares to Rachesky's MHR Fund Management LLC, putting 12 percent more of the stock in friendly hands and diluting Icahn's holding. Rachesky increased his stake by purchasing $100 million of notes from Kornitzer Capital Management and then exchanging them for stock. Icahn has called the transaction a "sham."
The studio, distributor the "Saw" horror films and producer of the Emmy-winning "Mad Men" TV series, announced the Rachesky deal days after a 10-day truce with Icahn expired.
Icahn claimed that Rachesky and other board members should be barred from voting their shares when he sued Lions Gate in New York Supreme Court on July 26.
Lions Gate is based in Vancouver and run from Santa Monica, California.
The case is Icahn v. Lions Gate, 651076/2010, New York state Supreme Court, New York County (Manhattan).


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Captain Moody's gift to Portland
Since 1807, the Portland Observatory has offered spectacular views of Portland's busy harbor and served as a beloved symbol of the city's rich maritime heritage. Named a National Historic Landmark in 2006, the Portland Observatory is the only known remaining historic maritime signal tower in the United States.
Tall Ships Portland at the Portland Observatory!
Saturday, July 18th, the Portland Observatory will be flying the flag of Iberdrola USA Tall Ships Portland!
Come check out the festival from the best view in town.
Admission will be $5 all day.
Visit the Observatory
View Larger Map
Portland Observatory138 Congress Street
Portland, ME 04101
(207) 774-5561


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Page 1
PEPFAR in Africa: An Evaluation of Outcomes
Eran Bendavid, MD1,2 and Jayanta Bhattacharya, MD PhD1
1Center for Health Policy and the Center for Primary Care & Outcomes Research, Stanford
University, Stanford, CA, USA
2Division of Infectious Diseases & Geographic Medicine, Stanford University Medical Center,
Stanford, CA, USA
Background—Since 2003, the President's Emergency Plan for AIDS Relief (PEPFAR) has been
the most ambitious initiative to address the global HIV epidemic. However, PEPFAR's effect on
HIV-related outcomes is unknown.
Objective—To assess PEPFAR's impact on HIV-related deaths, the number of people living
with HIV, and prevalence in Africa.
Design—Comparison of trends before and after the initiation of PEPFAR's activities in the
African focus countries with other African countries.
Setting—Twelve African focus countries and 29 controls with a generalized HIV epidemic from
Observations—451 country-year observations.
Intervention—A 5-year, $15 billion program for HIV treatment, prevention, and care that started
in late 2003.
Measurements—HIV-related deaths, the number of people living with HIV, and prevalence.
Results—Between 2004 and 2007, the annual change in the number of HIV-related deaths was
lower by 10.5% in the focus countries compared to controls (p=0.001). The difference in trends
between the group before 2003 was not significant. The annual growth in the number of people
living with HIV was 3.7% slower in the focus countries compared to controls from 1997–2002
(p=0.05), but during PEPFAR's activities the difference was no longer significant. The difference
Corresponding author: Eran Bendavid MD, Center for Health Policy and the Center for Primary Care & Outcomes Research, 117
Encina Commons, Stanford University, Stanford CA 94305 USA. Telephone: +1-650-724-3543, Fax: +1-650-723-1919,
Requests for Single Reprints: Eran Bendavid 117 Encina Commons Stanford, CA 94305 firstname.lastname@example.com
Potential Financial Conflicts of Interest: None disclosed.
Author Contributions: Conception and design: E. Bendavid
Analysis and interpretation of the data: E. Bendavid, J. Bhattacharya.
Drafting of the article: E. Bendavid.
Critical revision of the article for important intellectual content: E. Bendavid, J. Bhattacharya.
Final approval of the article: E. Bendavid, J. Bhattacharya.
Statistical expertise: E. Bendavid, J. Bhattacharya.
Collection and assembly of data: E. Bendavid.
Author Contribution and Conflicts of Interests
Eran Bendavid: I declare that I participated in originating the concept, in conducting the data collection, and data analysis. I did most
of the writing of the paper, including the final revision. I had full access to all the data in the study and had final responsibility for the
decision to submit for publication. I have no conflict of interests.
Jayanta Bhattacharya: I declare that I participated in elucidating the original concept, in the data analysis, critical review of the results,
and revising the manuscript. I have seen and approved the final version and I have no conflict of interests.
NIH Public Access
Author Manuscript
Ann Intern Med. Author manuscript; available in PMC 2010 June 28.
Published in final edited form as:
Ann Intern Med. 2009 May 19; 150(10): 688–695.
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in the change in HIV prevalence was not significantly different throughout the study period. These
estimates were stable after a sensitivity analysis.
Limitations—The selection of the focus countries was not random, and limits the
generalizability of the results.
Conclusions—We find evidence that, after four years of activity, HIV-related deaths declined in
PEPFAR's focus countries relative to sub-Saharan African controls, but trends in adult prevalence
were not different. Assessing epidemiologic effectiveness should be part of PEPFAR's evaluation
Alleviating the burden of HIV in sub-Saharan Africa is one of the great challenges of our
time (1). HIV is the leading cause of death in Africa, and is responsible for a reduction in
life expectancy in many countries (2). Available resources for HIV in less developed
countries expanded more than five-fold since the Declaration of Commitment on HIV/
AIDS, adopted by the UN General Assembly in 2001 (3,4), but the expansion has not been
evenly distributed. Since 2003, the US President's Emergency Plan for AIDS Relief
(PEPFAR) provided the majority of its $18.8 billion budget to 15 focus countries – 12 of
them in Africa – for HIV/AIDS prevention, treatment, and care (5,6). While the criteria for
selecting focus countries were not explicit, they were related the burden of disease, the focus
countries' governmental commitment to fighting HIV, administrative capacity, and a
willingness to partner with the US government. Nearly half of PEPFAR's resources were
spent on antiretroviral drugs and treatment infrastructure, and about a fifth was spent on
prevention programs, of which one third was earmarked for abstinence-only programs.
Through its various activities, PEPFAR aimed to support the provision of life-saving
antiretrovirals to 2 million people and prevent 7 million HIV infections in the focus
countries. Among the three major funders of HIV/AIDS programs – the others are The
Global Fund to Fight AIDS, Tuberculosis, and Malaria and the World Bank – PEPFAR is
unique in its distinctive approaches and disproportionate funding of a few countries (7–10).
In July, 2008, the US Senate reauthorized PEPFAR with a $48 billion budget for the next
five years, including a broader emphasis on strengthening health systems (11). The US
leadership in the battle against HIV has been one of its most important legacies in Africa
(12,13). However, despite the substantial financial commitment and the important role
PEPFAR plays abroad, no quantitative evaluation of the program's outcomes has been
completed. The original legislation mandated a short-term evaluation that was completed by
the Institute of Medicine in 2007 (14). Their report scrutinized PEPFAR's ability to meet its
targets for delivery of prevention, treatment, and care services in the focus countries, and
found that within 2 years, PEPFAR supported expansion of HIV/AIDS activities in the focus
countries; however, it did not evaluate health-related outcomes such as HIV mortality,
incidence, or prevalence.
The number of human lives affected and the financial stakes make it essential to assess the
impact of PEPFAR's investment in Africa. Although the full impact of PEPFAR may not be
felt for years, an ongoing evaluation of programmatic outcomes is central to the direction of
future policies. We undertake the first quantitative evaluation of HIV-related outcomes in
the focus countries compared with other countries in sub-Saharan Africa with a generalized
HIV epidemic.
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Country Selection
All countries of central, east, west, and south Africa and the island nations of Cape Verde,
Comoros, Madagascar, Mauritius, São Tomé and Príncipe, and Seychelles were eligible for
this analysis. We excluded countries if they did not have epidemiologic data or if their HIV
epidemic was not generalized. Generalized epidemic was defined as HIV prevalence of over
1% in antenatal clinics and a predominantly heterosexual mode of transmission (9,15). The
countries which PEPFAR selected as focus countries were examined as an intervention
group, while all other African countries with a generalized HIV epidemic were designated
Data Sources
The joint United Nations Programme on HIV/AIDS (UNAIDS) has monitored the
Declaration of Commitment on HIV/AIDS by working with individual countries to measure
the global epidemiology of HIV/AIDS (16). We used country and year epidemiologic data
obtained through UNAIDS from 1997 to 2007 as the outcome variables for this study.
UNAIDS determines the prevalence trends using sentinel and population based surveys. The
prevalence estimates, vital registry data, and model-based calculations are then used to
determine mortality and the number of people living with HIV. All the estimates are given
uncertainty bounds which depend on the quality of the primary data and the strength of the
assumptions used in the estimation process (17).
We obtained data on Global Fund allocation of resources, population structure, governance
indicators, life expectancy, and per-capita gross domestic product from publicly available
databases (10,18–20).
Study Period and Outcomes
We chose two study periods for this analysis: an early period, from 1997–2002, prior to the
onset of PEPFAR; and a late period, from 2004–2007, during PEPFAR's activities. We
excluded 2003, the watershed year when PEPFAR's operations were getting organized.
Three outcomes of interest were examined: HIV prevalence among adults age 15–49,
number of deaths due to HIV/AIDS, and the number of adults living with HIV. We used
these indicators as outcomes because they reflect the most consistent measures for cross-
country comparisons available over time. The indicators are publicly available (21).
Statistical Analysis
We compared trends of the epidemic outcomes between the focus and control countries
during the two time periods noted above. The early period represented the trends of the
epidemic absent PEPFAR activity, while the analyses of the late study period represented
the trends during PEPFAR's activity. We tested the hypothesis that the epidemic in the focus
countries showed greater improvement (or lesser worsening) than in the control countries
after the onset of PEPFAR's activities. We included the earlier time period in order to
separate the effects of PEPFAR from the natural course of the epidemic and any between-
country differences; that is, we wanted to compare not only the relative trends after
PEPFAR, but also any changes in the relative trends after the onset of PEPFAR.
We analyzed the trends using a fixed-effects model for longitudinal data (22). We fixed the
time and country effects and clustered by country to account for within-country correlation
of observations over time (23). The year, PEPFAR designation as a focus country, and an
interaction term between them were included as predictors in the unadjusted model. Except
for prevalence rates, the outcomes we examined depend on the size of the population. To
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account for that, we examined the percentage change in the outcomes of interest by using
log transformations of the outcomes (24). For prevalence rates, we report the difference
between the focus and control countries of the change in prevalence rather than the
difference in percentage change. We report the interaction term coefficient, which estimates
the difference in the trends between the focus and control countries. For example, a
coefficient of −2% in the number of deaths from 2004 to 2007 suggests that, during that
period, the percentage change in the number of deaths was 2% less in the focus countries
than in the controls (which means that deaths were rising more slowly or descending more
rapidly, depending on the overall trend). We used Stata 9.2 (StataCorp, College Station,
Texas) for all analyses.
In adjusted analyses, we accounted for baseline HIV prevalence (1997), population size, life
expectancy, per-capita gross domestic product, the amount of funding from the Global Fund
for HIV per capita, and four measures of governance from the World Bank's Worldwide
Governance Indicators: control of corruption, political stability, rule of law, and government
effectiveness (20). The Indicators measure the quality of governance in over 200 countries
based on 35 data sources from 32 organizations. They have been available since 1996, and
are widely used in development research (25,26). We also changed the model structure to
allow for random year effects. Since none of these additional analyses changed the direction
or significance of the relative effect of PEPFAR, we report the results of the unadjusted
To account for the assumptions and imprecision in the UNAIDS data, we did two different
sensitivity analyses. First, we performed a Monte Carlo process where the outcome variable
was drawn randomly within the uncertainty bounds for each country-year, and the analysis
was repeated 1,000 times. We also performed a sensitivity analysis where we randomly
selected groups of "focus" countries and ran the analysis 1,000 times to verify our analyses
were not biased in favor of finding significant differences (23).
This work was supported in part by a training grant from the Agency for Healthcare
Research and Quality. The funding agency had no part in the design and conduct of the
study; collection, management, analysis, and interpretation of the data; and preparation,
review, or approval of the manuscript.
Baseline Parameters
We examined twelve PEPFAR focus countries and 29 control countries from sub-Saharan
Africa for the analysis. Tables 1 and 2 show the selected countries and their baseline
characteristics, respectively. The focus countries had a significantly higher average
population (37 vs. 11.7 million people, p<0.01), but there was no difference in the life
expectancy of men or women. The per-capita disbursements from the Global Fund were
slightly more generous in the control countries, but the annual per-capita gross domestic
product was significantly lower in those countries ($1,935 vs. $4,094). The focus countries
ranked higher than the controls on all governance indicators – significantly higher in
government effectiveness – at the time of PEPFAR's start. The adult HIV prevalence was
higher in the focus countries throughout both study periods (p<=0.05).
Outcome Measures
Number of Deaths from HIV/AIDS—The number of deaths from HIV/AIDS rose in the
first period, but declined in the second period in the focus countries and leveled off in the
controls (Figure 1). Prior to 2003, the annual percent increase in the number of deaths due to
Bendavid and Bhattacharya Page 4
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HIV was 3.5% higher in the control countries, but that difference was not significant
(p=0.22). During the second study period, however, the death toll from HIV decreased much
more rapidly in the focus countries compared to the controls. During this period, the
difference in the percentage change was 10.5% lower in the focus countries (p=0.001, Table
3). Figure 2 shows that the difference in death rates between the groups of countries started
after 2003, and was most pronounced between 2005 and 2006, after nearly 3 years of
PEPFAR activities.
Number of People Living with HIV/AIDS—The number of people living with HIV/
AIDS rose in the focus and control countries throughout both study periods (Figure 1). The
annual percent change in the number was lower by 3.7% in the focus countries during the
early period (p=0.05, Table 3). In the late period, during PEPFAR's activities, the annual
percent rise in the number of people living with HIV/AIDS was slower in both groups of
countries. However, the difference (1.7% lower in the focus countries) was no longer
significant (p=0.12). That is, between the early and late periods the focus countries
experienced a relative acceleration in the number of people living with HIV/AIDS compared
with the control countries. Figure 2 shows the difference in the annual percent change
diminishing (getting less negative) after 2003, while the difference in the number of people
living with HIV/AIDS was negative (rise was slower in the focus countries) before 2003.
HIV Adult Prevalence—The HIV prevalence in both groups of countries peaked by 2002
(Figure 1). Before 2003, the prevalence rose faster in the focus countries compared to the
controls (0.05% faster annually), an insignificant difference. During PEPFAR's activities,
the difference in prevalence change between the groups was nearly 0% (p=0.95), as both
groups of countries experienced a gradual decline of about 0.1% annually in the HIV
prevalence in the adult population. Figure 2 shows that the difference in the adult prevalence
diminished throughout the early period, and remained stable around 0% difference after
2003. Additional details on the regression models are provided in Supplementary Tables 1–
Sensitivity Analysis
To assess the stability of our analyses, we used the uncertainty bounds provided by
UNAIDS to select values for the outcome measures. We used a uniform distribution to draw
a value for the outcome variables, avoiding assumptions about the true value. We then used
the randomly picked value for each country-year as the value for the regression. This
process was repeated 1,000 times, and we collected the mean of the coefficients and p-
values. Using this procedure, the difference in the annual percent change in the deaths due to
HIV/AIDS was −2.0% during the early period (p=0.29), and −9.7% in the late period
(p=0.02) in the focus countries compared to controls. We obtained a significant difference in
deaths from HIV in 90.7% of the iterations in the late period, but only 3.7% of the iterations
in the early period. The full results of the sensitivity analysis is provided in Supplementary
Table 7.
Our second procedure for verifying the stability of our results, where we randomly selected
groups of countries to serve as "focus" countries for the analysis, showed that any
significant differences, especially in the number of deaths, disappeared.
This study examined the impact of PEPFAR by comparing changes in three outcome
measures between the focus countries and other countries with a generalized HIV epidemic
in sub-Saharan Africa, before and after the onset of PEPFAR. Our results show that after
Bendavid and BhattacharyaPage 5
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text:
Talking walls
La Jolla Playhouse's Without Walls Festival steps outside for a "three-day arts party"
Jeff Smith noon, Oct. 4
Philharmonic String Orchestra and Soloist Ensemble open season with Osvaldo Golijov's "The Dreams and Prayers of Isaac the Blind" and "Lullaby and Doina," with soloist Robert Zelickman (clarinet). Program includes selections by Rachmaninoff, Odeon Parthos, Thomas Tallis, Vivaldi, and Bach. 858-592-9790.
6660 Cowles Mountain Boulevard, San Diego, 92119
Get directions
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Sanctification and Growth
Children of the Living God
Book by Sinclair Ferguson
Jesus Christ taught his disciples to call God 'Our Father', and to live as members of his family. Although simple enough for every Christian to understand this is also so profound that its implications take a lifetime and more to … Learn MorePaperback $8.00 $6.40 Add to Cart
Five Things Every Christian Needs to Grow
Book by R.C. Sproul
People need to maintain a diet of nutritious foods if their bodies are to grow and thrive. But what do the people of God need in order to grow and thrive in the Christian faith? In this book, noted theologian … Learn MoreHardcover $15.00 $12.00 Add to Cart
Also available in one other format
Respectable Sins
Book by Jerry Bridges
Have Christians become so preoccupied with the major sins of our society that we have lost sight of our need to deal with our own more subtle sins? Jerry Bridges returns to his trademark theme of holiness and addresses a … Learn MoreHardcover $20.00 $16.00 Add to Cart
In Christ Alone: Living the Gospel-Centered Life
Book by Sinclair Ferguson
Noted theologian, pastor, and educator Dr. Sinclair B. Ferguson explores aspects of the person and work of Jesus in his latest book, In Christ Alone: Living the Gospel-Centered Life. This collection of articles, published earlier in Tabletalk magazine and Eternity … Learn MoreHardcover $18.00 $14.40 Add to Cart
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Faith: The Evidence of Things Unseen
Teaching Series by R.C. Sproul
The author of Hebrews writes that faith is the substance of things hoped for and the evidence of things unseen. Yet it is not always clear how we should express our faith. In addressing the ways people have distorted the … Learn MoreCD $17.00 $15.30 Add to Cart
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Overcoming the World: Grace To Win The Daily Battle
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The Pursuit of Holiness
Book by Jerry Bridges
What does holiness look like? For starters, it doesn't look anything like perfection. And it doesn't necessarily look like victory. Mostly, it consists of effort, prayer, grace, and obedience. "Scripture speaks of both a holiness we have in Christ before … Learn MorePaperback $13.00 $10.40 Add to Cart
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The Micah Mandate: Balancing the Christian Life
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Micah 6:8 commands the people of God to do justice, love mercy, and walk humbly with the Lord. This book provides guidance for balancing these requirements in the Christian life that we might be more faithful to our heavenly Father. Learn MorePaperback Please check back soon to purchase this item.
Golden Booklet of the True Christian Life
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Golden Booklet of the True Christian Life has inspired readers around the world for more than four centuries.Now in paper, this classic devotional will guide you on how to apply biblical principles to everyday life. Originally part of John Calvin's … Learn MorePaperback $9.00 $7.20 Add to Cart
The Pilgrim's Progress
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The Valley of Vision
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In this classic volume, edited by Arthur Bennett, the prayers of the Puritans are brought to life. Including prayers of Richard Baxter, John Bunyan, Isaac Watts, Charles Spurgeon, and others, The Valley of Vision is a selection of petitions and … Learn MoreBonded Leather $26.00 $20.80 Add to Cart
Heart Aflame: Daily Readings from Psalms
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"Blessed is the man … his delight is in the law of the Lord." John Calvin described the Psalms as "an anatomy of all the parts of the soul." The description is an apt one, says Sinclair B. Ferguson in … Learn MorePaperback $15.00 $12.00 Add to Cart


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Candlewood Suites Bismarck
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A riverboat cruise
... outpost during the settlement of the west
and for providing protection from the Indians.
The park is at the confluence of the Heart and Missouri and there are
many great walking trails and a bike path that runs about 7 miles to the town
of Mandan. Glad I made a reservation
for a Saturday night stay because the park was full except for some primitive
sites. In the evening I ...
Lewis and Clark at Fort Mandan
... were able to make a U-turn in their tiny parking lot and stopped along the side.
As soon as we stopped we saw Seaman's statue near the Missouri River. Very moving.
For many years the name of the dog was thought to be "Scannon". While deciphering the travel journals of ...
Lewis and Clark and Indians
... more salt and pepper; and could have used more of the hamburger filling; but overall good and filling. Both Peg and I had the soup of the day, Knoephla. This was a cream soup with bacon, potatoes and small (bean sized) dumplings. Peg had the country fried steak and said it was the best she had ever had.
After lunch we went to a restoration of Fort Mandan which L & C named in honor of the local tribe. They wintered there with a garrison of + or – 44 men, some left ...
... had been engaged 31 years ago and had broken up. They both had married others and each had two children by those marriages. Their respective spouses had died and the lady had heard that her previous fianc� had also died. Earlier this year he, not being dead, was watching a band at a bar in International Falls MN due to his interest in music. He walked up and was talking to a band member. The young man identified himself and told the man that he had taught him to play guitar when he was ...
Canada Day in North Dakota USA
... made a terrible racket! After more miles, we came to Moorehead, Minnesota - the twin city to Fargo, North Dakota just across the Red River. We drove through both cities to the Centre of Fargo, just because we've wanted to see Fargo ever since the movie came out! It's actually a cool town, with some great old buildings, like the Art Deco movie theatre, now a National Heritage building. Had a great sandwich at the Smiling Moose Deli, then on the road ...


text:
This profile was last updated on 9/3/15 and contains information from public web pages and contributions from the ZoomInfo community.
Dr. Pravin MishraWrong Dr. Pravin Mishra?
Chief Executive Officer
Phone: (630) ***-**** ext. ***Email: p***@***.com
Pugmarks Inc
1717 Park Street Suite 110
Naperville , Illinois 60563
United States
Company Description: Pugmarks was founded in 1996. Since then it has emerged as a niche managed hosting, infrastructure management and server management company. Pugmarks specializes... more
Pro2015_Iteration9_NoTests.148[01] SEIDXWK-41


text:
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"Rabbit of Seville"
The Looney Tunes episode during which Bugs Bunny makes a salad on Elmer Fudd's head after massaging it with his feet
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Let's Talk About Ben Carson's Oregon Shooting Superhero Delusion
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Lyn, it depends on whether he has had an "event" (heart attack or tia or stroke) before. For every 3000 people who have not had an event before, taking aspirin will prevent one heart attack in a man and one ischaemic stroke in a woman. But three people are likely to be admitted with a gastric bleed. Also a higher incidence of indigestion . So in those circumstances, many doctors are stopping low dose aspirin as more people are hospitalised with side effects, than with what they were trying to prevent. In people who have already had a heart attack or stroke, the odds are better at secondary prevention, and so it is recommended that they carry on taking it.
Your dad should talk to his doctor before he stops taking any medication, but if he has not had a previous event, , I wouldn't worry too much.
Can you get iplayer busy lizzie.?
Glad your dad has been found Dove, maybe he needs a tracker like when new cars go missing?
My lights have fused downstairs, and I cant find the torch, so it will have to wait until daylight. I'm off to bed now.
Salvia amistad in front of yellow rudbeckias. I know you dont like yellow, but autumn needs yellows and oranges..
I only know because i had a run in over an interim tree preservation order for a tree in the middle of a car park at the back of the shop.
Man from ashfield council turns up with said interim tpo for a walnut tree. But it's not a walnut tree says I. Its a pear tree. How do you know? He says.
Doh maybe because it has pears on it!!!
Pear tree came down.
I had a conversation the other night with OH about microchipping. We do it with dogs, wouldnt it be a good idea to do it to all kids at birth.? Then if they got lost and couldnt remember who they are, you can send them home. He settled on, give them an iphone with a tracker in. All right until they lose the iphone.
Mum told me a little story about last time they went to Disneyland. Dad came out of the toilets with his flies undone. He couldn't find the tag to pull up the zip. So they went around the corner and mum was on her knees trying to find the zip pull, in front of dad. Only trouble was the quiet corner was the staff entrance. Picture mickey mouse watching a 75 year old on her knees , fiddling with the fly of a 77 year old man.
All perfectly innocent.
Now he has a piece of string attached to make it easier to pull up.
Ay up mi duck. Arent Doff in Hucknall? Thats Ashfield, Nottinghamshire, not Nottingham.
It will need to go under cover, or you can take cuttings if it has stopped flowering. I usually do the cuttings when i cut them down in late october to go in the greenhouse.
I found three lurkers in the courgette patch. Now if I'd been going for the biggest marrow competition I would be happy. I have a flower on the discovery apple, and last years brugmansia cuttings are flowering, despite not being fed and in too small a pot. Funny old year.
You could do either. Carefully lever up a few seedlings and pot on in gritty compost. They look a bit crowded there.
Clarkia elegans


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Earn bonus Starpoints® & more for your check-ins when you connect your SPG® & foursquare accounts. Visit spg.com/foursquare to view latest earning opportunities
Staff I very friendly. Wifi was pretty much useless and refuel section was far from gourmet choices. Cappuccino machine on the blink as well. Bed was comfy though..
Lobby and room/baño layout
Pet Friendly! Well behaved dogs under 50lbs stay at no extra charge... Unless they have an accident :/
Comfortable...bit quirky but room was nice and bed comfortable! :-)
Got in late check-in went ok. Although the room was modern & looked decent it did have a wet dog smell. Idky but that seems to be a running theme for Cali hotels so bring air refresher spray with you.
Found stain on the sheets, and they told us cleaning staff already left for the day, and we had to change sheets ourselves... :(
Very comfortable, modern and clean. Being your gym clothes and a bathing suit. The espresso machine is an awesome touch :)
Ask for a room facing mountain unless you enjoy jet engine noise from 1 1/2 miles away.
Rooms are very small for the price. Avoid the chicken wings in the wxyz bar. I really miss having a lazy boy chair when I watch Tv or on the computer. The staff Is the Best and 2nd to none though!
The Internet connection blows. Go find a Starbucks or Panera Bread.
The girls behind the desk are super nice and hot too! ;)
You have to try the Rancho Cucamonga Tea on Wednesday Night. Just ask for Shawn @ WXYZ Lounge.
You fancy huh? You fancy huh? Hair done, nails done, everything done done!
I love all the girls that work in the morning.
Nice hotel.
Nice clean and new hotel :-)
looks new and fancy
Bring your furry friend. Aloft is pet friendly!
Try the Tequila Marinated Chicken Wings....amazing flavor. This is the first Aloft that I've stayed at (Stayed at 6 total) that had a full menu at it's W XYZ bar in the lobby! Also love the "Aloft T
If you're here Sunday night, trash day is Monday morning around 5:30am. Be prepared to hear slamming dumpsters if your room faces east.
Somehow highballs are $12 here....


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View History
|Changed 14,000 to 1,400.
|Jun 17, 2015
|Add new Web site: e-WV: The West Virginia Encyclopedia - Biography of Randy Moss.
|May 14, 2015
|Added mention of Moss becoming a TV football analyst.
|Aug 21, 2013
|Added San Francisco's loss to the Baltimore Ravens in the Super Bowl.
|Feb 04, 2013
|Updated article to mention that Moss ended his retirement and signed with the 49ers.
|Mar 13, 2012
|Added his retirement and select career statistics.
|Aug 02, 2011
|Standardized styling of NFL seasons throughout article.
|Feb 04, 2011
|Added mention of Moss being waived by Minnesota and claimed by the Titans.
|Nov 03, 2010
|Moss's trade to the Vikings added.
|Oct 06, 2010
|New article added.
|Dec 17, 2009


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But it's combined by the user at runtime, not by canocal. The GPL allows an end users to do this.
This is a way that people kid themselves about the GPL. If the user were really porting ZFS on their own, combining the work and never distributing it, that would work. But the user isn't combining it. The Ubuntu developer is creating instructions which explicitly load the driver into the kernel. These instructions are either a link script that references the kernel, or a pre-linked dynamic module. Creating those instructions and distributing them to the user is tantamount to performing the act on the user's system, under your control rather than the user's.
To show this with an analogy, suppose you placed a bomb in the user's system which would go off when they loaded the ZFS module. But Judge, you might say, I am innocent because the victim is actually the person who set off the bomb. All I did was distribute a harmless unexploded bomb.
So, it's clear that you can perform actions that have effects later in time and at a different place that are your action rather than the user's. That is what building a dynamic module or linking scripts does.
There is also the problem that the pieces, Linux and ZFS, are probably distributed together. There is specific language in the GPL to catch that.
A lot of people don't realize what they get charged with when they violate the GPL (or any license). They don't get charged with violating the license terms. They are charged with copyright infringement, and their defense is that they have a license. So, the defense has to prove that they were in conformance with every license term.
This is another situation where I would have a pretty easy time making the programmer look bad when they are deposed.
Regardless of what Ubuntu has convinced themselves of, in this context the ZFS filesystem driver would be an unlicensed derivative work. If they don't want it to be so, it needs to be in user-mode instead of loaded into the kernel address space and using unexported APIs of the kernel.
A lot of people try to deceive themselves (and you) that they can do silly things, like putting an API between software under two licenses, and that such an API becomes a "computer condom" that protects you from the GPL. This rationale was never true and was overturned by the court in the appeal of Oracle v. Google.
Aggregate means two programs that are not combined and just live on the same filesystem. In the case of a filesystem driver, it's read into the kernel space and touches unexported APIs of the kernel and various kernel internals.
It is thus a derivative work.
If I had to guess, I'd say heritable immunity.
const int one = 65536;
As an aside (that means off-topic, guys) this looks like part of a fixed-point arithmetic implementation. It may not be as silly as you think.
Those genes are not expressed, and we don't have copies of those viruses floating around our bloodstream.
Probably, and for the most part. But we used to think the genome was mostly "junk DNA" before we understood that much of it was homeotic in function. It seems to me that virus copies would not be conserved over time unless they were serving some function.
Of course, Hotmail wasn't running linux . . .
It could have, but it would have needed more servers, though not as many as to switch to windows.
Hotmail was on FreeBSD, and stayed so for years
Given the emissions requirements for a '59, I'm skeptical.
Kind of like naming the coal exports from North America---in 1491 . . .
(for those of you younger than the cars I prefer to drive, a '59 isn't exempt from emissions for being old enough; it doesn't have to, as there *were* no emissions standards or tests until a few years later. [now, if he put in an engine from a later year, he has to meet *those* emissions, but then the year of manufacture is irrelevant. ])
The Macintosh is Xerox technology at its best.


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MD Headlines: Grillo graduates to PGA Tour
Emiliano Grillo edges Chez Reavie to win the Web.com Tour Championship. Lauren Thompson brings you the latest headlines from the world of golf.
Emotional Olesen talks 'special' Dunhill win
Thorbjorn Olesen talks about his win at the 2015 Alfred Dunhill Links Championship.
King of the 'Hill: Olesen wins at St. Andrews
Thorbjorn Olesen's putter wasn't as hot in the final round, but he still hung on to win at St. Andrews.
Olesen rides hot putter to Alfred Dunhill lead
Thorbjorn Olesen rode a hot putter to the top of the leaderboard in round three of the Alfred Dunhill Links at St. Andrews.
Koepka to career best in rankings after Dunhill finish
Brooks Koepka moved to a career-best 12th in the Official World Golf Ranking, thanks to his second-place showing at the Alfred Dunhill Links Championship.
Olesen: 'It's been tough this season'
Thorbjorn Olesen talks about some of his struggles on the European Tour this season and recaps his Saturday round at the 2015 Alfred Dunhill Links Championship.13 birdies over his las 26 holes is seeking his third career European Tour victory. His last win, the 2014 Perth international. Aphibarnrat also talked about his difficulties this season. He's currently 124th in the race
Bogey-free Fitzpatrick shares lead at Czech Masters
Second round highlights from the 2015 D+D Real Czech Masters, where Matthew Fitzpatrick and Pelle Edberg are tied for lead at 11-under. Watch the European Tour on Golf Channel.be a breakthrough week for some of the young guns on the European Tour , and the D&D Real Czech Masters. Not many proven winners on the leader board at halfway, but certainly a day that the 19 year old Czech amateur Vitek Novak will long remember. A 68, for three under. And he makes the cut. Only the second Czech ever to do so on the European tour . Thorbjorn Olesen set up a torrid season. This is only the fourth cut he's made. And he's really challenging for the title.
Cable guy: Olesen gets 'mulligan' after drive hits power line
Thorbjorn Olesen's errant drive strikes power line on the 4th hole during Friday play at the 2015 Made in Denmark. Watch the European Tour on Golf Channel.play. It's your here. That's fine. In two, one. Oh yeah, two tee shot . Yep. Yep. You're playing your second, yeah? So he's had it confirmed by presumably people in the crowd or maybe one or
Fantasy: Soren Kjeldsen a contender in Denmark?
Will Gray joins Lauren McDonald to choose a 'Contender and Pretender' for the 2015 Made in Denmark. Play alongside our experts by logging onto www.golfchannel.com/fantasyThis week on the European Tour Mark Warren looks to defend his title in Denmark. Lauren McDonald joined by our fantasy expert Will Gray here to play some fantasy golf. Will let's play Contender Pretender today. If we're talking about the in Denmark, we might as well highlight two Danes, one good, one not so much. Let's start with the contender, Soren Kjeldsen . He won the Irish Open, surprised many with that victory. And a lot of people thought that he might slow down, myself included, after that win, but that was not the case. He has really powered through this summer and played some really good golf, including a top 15 finish A couple weeks ago at the WGC Bridgestone Invitational. He finished 15th at this event last year. I expect him to have another good week. On the flip side, Thorbjorn Olesen. It's been a long time since we talked about Thunder Bear in terms of fantasy golf. He was playing in the PGA Tour a lot, as recently as two years ago, but since then, he's had injury issues, his game has left him. He's all the way down to 136. in the world ranking and has missed seven out of his last nine putts. So even though the Danish fans are gonna be behind Thorbjorn Olesen, I don't think he's gonna be around for the weekend, Lauren. Only one top 20 finish for Thor on the European tour . I'm gonna have to agree with you there. I like that you guys are on good terms. Yeah we are. Thor, he's
Olesen Comments on Return to Golf
Thorbjorn Olesen comments after a first round 65 at the 2015 Afrasia Bank Mauritius Open. Watch the European Tour on Golf Channel.
Olesen among three tied at Mauritius Open
Thorbjorn Olesen, Carlos Pigem, and Jeunghun Wang are tied for the lead after first round 65s at the 2015 Afrasia Bank Mauritius Open. Watch the European Tour on Golf Channel.the Aparatian Bank Marishus Open, being tri-sanctioned by the European Sunshine and Asian tours . One of the leading players. Here had an absolute nightmare. This is a par miss on the 14. In the end he finished with a 77, six over par. And that Only thanks to an Eagle at the last, his only sub-par hole of the day. Playing partner Thomas Bjorn also found the going tough although this was a glorious approach into the par five seventh, very nearly an Eagle One of
MD Headlines: Tiger struggles on 18
On Thursday at the 2015 Players Championship, Tiger Woods opened with a 1-over par 73 in his first competitive round since his top 20 finish at the Masters. Lauren Thompson brings you the latest headlines from the world of golf.of May I'm Lauren Thompson and these are your morning drive headlines. Tiger Woods opened with a one over par seventy three in his first competitive round since top twenty finish at the masters in april Woods chipped in for birdie on the seventeenth to get to one under par for the day. But closed with a double bogie on eighteen. Woods teed off friday morning at eight thirty-nine a.m. eastern alongside Adam Scott and martin Khmer as the three former champions looks to put themselves in position to make a move on the current leader. And 2016 European Ryder cup Captain Darren Clarke withdrew from the Players Thursday in the middle of his opening round. Clarke told tournament officials that he injured his wrist prior to to his round while warming up on the driving range and decided to tee off alongside Scott Brown and Seung-Yul Noh. Another field of notes. Paul Casey . He withdrew prior to the second round, due to illness. And also, on the European tour, more news. Thorbjorn Olesen leads the
Olesen one back after 54 at Mauritius Open
Thorbjorn Olesen talks about his Round 3 performance at the 2015 Mauritius Open.best score I could because, I hit a lot of poor, poor tee shots . And, but, I saved an incredible and, the save on 17 also was amazing and then, so, it was, it was a tough round today and, It took a lot of concentration and I, I belive in myself. Is that one of the pitfalls of this golf course ? If you're not straight off the tee, what are the problems you had today? Yeah definitely the rough is tricky and there's
Golfing World Player Profile: Thorbjorn Olesen
Golfing World chats with rising Danish star Thorbjorn Olesen who has battled back from an early season injury, impressing on his return to action on the European Tour.back here and playing on tour again. Fellow Dane and close friend Soren Hansen has also Suffered with injuries and was a good sounding board. I've been talking quite a lot with him because he's had some hand injury also and been out for, I think he was out for 13 months actually. So I've been spoken to him quite a


text:
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Cottage Ivory Chest of Drawers
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Cottage Ivory Chest of Drawers is rated out of 5 by 10.
Rated 4 out of 5 by M from I would recommend this product. Excellent delivery service, on time, extremely helpful delivery man for whom nothing was too much trouble.
Date published: 2015-03-24
Rated 5 out of 5 by june from Cottage Ivory Chest of Drawers Bought this chest to complete my new kitchen. It fits lovely under units giving not only extra drawer space, but adding a funky touch. Love it!
Date published: 2014-08-01
Rated 4 out of 5 by Spud from Perfect for the job We bought this cabinet to go in our Computer room, it's a nice size and great for all kinds of bits and pieces. It's sturdy and comes already constructed, but a little overpriced.
Date published: 2014-02-17
Rated 5 out of 5 by Josiepee from I would recommend this product We bought this for our hall to put gloves, hats, keys etc in, and it is surprisingly roomy. Looks absolutely great, and so nice that it is fully built - just take it out of the box!
Date published: 2013-12-22
Rated 5 out of 5 by Mitty from Cottage chest A good product for my small bedroom,goes well with console unit. White colour not ivory which is perfect for me.. Seagrass baskets are a bit scratchy.
Date published: 2013-10-08


text:
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Deep Vein Thrombosis Health Center
Deep Vein Thrombosis - When To Call a Doctor
Call 911 or other emergency services if you have pulmonary embolism symptoms, including:
- Sudden shortness of breath.
- Sharp chest pain that sometimes becomes worse with deep breathing or coughing.
- Coughing up blood.
- Fainting.
- Rapid pulse or irregular heartbeat.
- Anxiety or sweating.
Call your doctor immediately if you have DVT symptoms, including:
Recommended Related to DVT (Deep Vein Thrombosis)
10 Questions to Ask Your Doctor About DVT
1. What is DVT? And how dangerous is it? DVT stands for deep vein thrombosis, a blood clot in one of your body's deep veins, usually within a muscle of your leg. The biggest danger is that part of the clot could break off and travel to your lungs. It could cause a blockage known as a pulmonary embolism, or PE. Your doctor will talk to you about how likely that is to happen with your clot. 2. Are you sure I have a DVT? How is it diagnosed? People with a deep-vein clot in their leg...
Read the 10 Questions to Ask Your Doctor About DVT article > >
- Swelling, warmth, or tenderness in the soft tissues of your leg. Swelling may also appear as a swollen ridge along a blood vessel that you can feel.
- Pain in your leg that gets worse when you stand or walk. This is especially important if there is also swelling or redness in your leg.
Who to see
Health professionals who can diagnose a blood clot in the leg include:
- Nurse practitioners.
- Physician assistants.
- Family medicine doctors.
- Internists.
- Surgeons.
- Emergency room doctors.
To prepare for your appointment, see the topic Making the Most of Your Appointment.
In this article
WebMD Medical Reference from Healthwise


text:
Bernard Mannes Baruch
1 portrait of Bernard Mannes Baruch
© National Portrait Gallery, London
Bernard Mannes Baruch
by Dorothy Wilding
chlorobromide print on tissue and card mount, 6 February 1951
9 3/8 in. x 7 1/4 in. (237 mm x 183 mm)
Given by the photographer's sister, Susan Morton, 1976
Photographs Collection
NPG x4376
Click on the links below to find out more:
Sitterback to top
- Bernard Mannes Baruch (1870-1965), Economist and philanthropist. Sitter in 1 portrait.
Artistback to top
- Dorothy Wilding (1893-1976), Photographer. Artist associated with 2142 portraits, Sitter in 30 portraits.
Subject/Themeback to top
Tell us moreback to top
Can you tell us more about this portrait? Spotted an error, something missing, or do you know anything that we don't know? If you have any information to share please complete the form below
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text:
Deviant Art
HurtIll cry these tears and hopeHurt7 years ago in Traditional Fixed Forms More Like This
Hope that my screams will reach your ears
That you will come to save me
Is it possible to die of a broken heart?
I feel thats whats happening now
Im crying now
These relentless tears
I see your face
And my heart twists
It hurts to know you wont love me
Because Im not what youre expecting
Im not what you want
It still hurts here
A pain I feel that cant be erased
Please make the pain stop!
Make it stop please
Im still crying now
With these words Im hoping my heart can forget you
But with the air of love around
It makes it hard to be able to forget
And the way you made my heart hurt
How you turned my love for you into pain
I dont know how I can forget that
Im reaching out for you
Hoping you will come into my arms
To make the pain stop
I look toward the sky
Thinking that maybe youre under the same stars I am
Feeling the breeze on my skin
Sending shivers down my spine
true loveIm never going to leave your side,true love8 years ago in Free Verse More Like This
These words my vow to you.
You say Ill cherish you forever,
Youll always be true.
Sickness and health,
Well be together through it all.
Ill be there for you,
When you both rise and fall.
Be there till the end,
You say youll stay with me.
As I look into your eyes,
This truth I can see.
Honest and loving,
Care and concern.
Are all of the emotions,
Within your eyes burn.
I say I love you,
You say forever more.
Together well live forever,
Each year keeping score.
best friendsYou're my best friend,best friends9 years ago in Free Verse More Like This
But you're more than a friend,
You understand me like no one else could,
You make me smile when I'm down,
You've helped me turn my life around,
You're always there when I need a friend.
We help each other with our troubles,
We'll stick together through thick and thin,
We'll help each other to the end.
We've had our fights,
But never said goodbye,
And hopefully we never will
I can never stay mad at you for long,
And even if I could I know never would,
'Cause were sisters,
No matter what the tests say,
No matter what happens,
No matter what we go through,
We're best friends forever,
And sisters too.
Cutting away the pain....I cut my arms with razor bladesCutting away the pain....10 years ago in Free Verse More Like This
And watch it slowly bleed
To dull the pain I feel inside
My heart is just too weak.
I wish that I could walk away
From all the things I fear
I cut a little deeper now,
To shove away all the pain
With every single tear
Yet this can only last so long...
No longer can I live...
|Sta.sh Submit


text:
Simple can be fun. Simple can be addictive Simple can also be frustrating. Cubes—developed by George Buckenham—manages to be all three in beautifully annoying fashion.
Honestly, though, it's the great ambient pop soundtrack from Popolo that keeps me coming back to Cubes. Every time I want to throw my iPad to the ground, the swooping synths sand swirling aesthetic pulls me back in. Damn it all.
Cubes [$0.99, iTunes]


text:
Kathryn Shay spent five years riding fire trucks with a large city fire department, eating in their firehouses and interviewing hundreds of America's Bravest. Listen to the novels that resulted from her intense relationship with firefighters!
Three firefighters from the Malvaso family are trapped in a burning building and almost lose their lives. After they are rescued, they decide to change the way they've been living. Mitch, the eldest, wants to make some decisions about his dysfunctional marriage and spend more time with his kids. Jenn decides to have a baby - with her best friend, Grady. And Zach, the bad boy of the group, vows to make up for his past sins and become a better man.
©2010 Kathryn Shay (P)2013 Kathryn Shay
"Could not stop listening!"
I could not stop listening to this audiobook - I had to find out what happened to each and every one of the characters. It was touching and funny and - in the context of the genre - a really enjoyable light listen with some surprisingly touching moments, brought to life by Jeffrey Kafer's narration. He's got a great voice and it suited the story perfectly. I received a copy of this audiobook in exchange for my review and am delighted I had the chance to listen in!
I love all genres of books. However, when I listen to audio books as I clean, garden, drive they are better with a lot of heat!
"Great Book"
After a devastating fire, Mitch, Jenn, and Zach Malvaso vow to change their lives for the better. Mitch decides that he either has to make a serious commitment to making his marriage work or call it quits, Jenn decides she wants a baby, and Zach wants his wife back.
Megan Hale moved to Hidden Cove to escape the demons chasing after her. After her husband died in the line of duty and her father only a short time later, Megan knew that she had to leave the big city scene. She has finally found peace in the little town that is just like family. Her attraction to Mitch is as unexpected as it is complicated. Vowing never to be the 'other woman', Megan is adamant about not admitting her feelings for Mitch, and he feels the same way. This book is overcoming the trials of life and falling in love when you least expect it.
Although the story revolves mostly around Mitch and Megan, Shay has subplots with the other siblings that grab the reader and don't let go. I can't wait until her next book in this series comes out. I never understood exactly how much a firefighter risked until I read this book. The things that a firefighter has to know, along with the risks they take for strangers is humbling.
The emotion in this book is so overwhelming at times that I felt like crying. This is a well written book that I would highly recommend!
Jeffrey Kafer was outstanding with the delivery of the story.
"A Fun Read"
the book is fairly spread out between characters limiting in depth look at many of them
I enjoyed the interaction between the Mitch and his children especially.
Fun read for listening to in the car, reader does a good job with different voices so you can tell the difference between characters.
"Loved it!"
This is a great book with an even better story line. Can't wait for the next one.
"Well-written and well-narrated"
In this story about firefighters and paramedics and detectives, the personal lives of those who serve us are revealed. We get a glimpse of how the devotion of these heroes to their jobs impacts their private lives, and how they learn to cope with tragedy, betrayal, and interpersonal relationships. The characters were credible, the situations realistic, and the conclusion at the end was not rushed or forced. Jeffrey Kafer's narration moves the story along at a good pace, and kept my interest. His female voices were not contrived, and were believable. I found myself rooting for the main character, Mitch, and hoping somehow he could get free of his crazy wife. I completely forgot this story was being read to me, I felt like a fly on the wall. I am looking forward to listening to Mr. Kafer again, and would not hesitate to read a book by this author. It was a good match.
I received a free download of this book, but that did not influence my candid review of it.
"Romance, hardship, firefighters @ work"
Totally loved the story and the narration. Will immediately listen to all the other books of the series.
"Loved this book!"
Loved the story, and the narrator
Mitch for sure. It is sad when good people come to the end of a marriage.
Found his voice soothing and felt this story was better off for having a male reader.
"Favorite of them all"
This story is my favorite out of all the fire fighter books you will read in this series. Good books over all
"Okay listen, not my norm"
This listen was ok, I typically prefer a little more mystery. I don't really care for a predictable storyline. The author did surprise me on a couple of occasions.
"I kept waiting for the story to become better."
There are numerous "main" characters and the book jumped around enough to make it hard to follow.
Jeffrey Kafer was a decent narrator.
Storyline; storylines were hard to follow.
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text: We had such a great time at La Tourelle! We were there during the "off-season" but there was no lack of service. The spa was amazing and everyone who worked there was friendly and very accomodating. Our room was beyond our expectations with a beautiful view even in the dead of winter. The package deals are a great value and allowed us to relax and just enjoy the time. We will definitely be back, during any season!


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Tags: A History of the Navy in 100 Objects, USS Maine
Although sails and wind power had dominated naval propulsion for the previous five hundred years, it took less than fifty during the 19th century for every major navy to completely transition to steam power. Steam power opened the door to electricity generation, and the first American ships to have electricity had to be retrofitted to receive electrical systems. Our object today comes from the USS Maine, sunk in Havana, Cuba in 1898, and one of the first ships to be designed from the beginning with electrical power included.
Posted by ENS Chris O'Keefe in History, Navy, Podcasts
Tags: A History of the Navy in 100 Objects, USS Maine
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Princess Louisa Maria Theresa Stuart
8 of 9 portraits of Princess Louisa Maria Theresa Stuart
© National Portrait Gallery, London
Princess Louisa Maria Theresa Stuart
by Nathaniel Parr, after Unknown artist
line engraving, mid 18th century
11 3/8 in. x 14 in. (290 mm x 355 mm) plate size
Given by the daughter of compiler William Fleming MD, Mary Elizabeth Stopford, 1931
Reference Collection
Click on the links below to find out more:
Sitterback to top
- Princess Louisa Maria Theresa Stuart (1692-1712), Daughter of James II. Sitter associated with 9 portraits.
Artistsback to top
- Nathaniel Parr (died 1751), Engraver. Artist associated with 8 portraits.
- Unknown artist. Artist associated with 6307 portraits.
Related worksback to top
- NPG D34733: Princess Louisa Maria Theresa Stuart (from same plate)
Subjects & Themesback to top
Tell us moreback to top
Can you tell us more about this portrait? Spotted an error, something missing, or do you know anything that we don't know? If you have any information to share please complete the form below
Exhibitions and displays
- The Tudors Reimagined: George Perfect Harding
Until 14 February 2016
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Our news archive spans the last 30 days. Perhaps you'd like to view the oldest stories available.
Recent Headlines
in Music
Go to rock 'n' roll camp with Tony Iommi
The Black Sabbath star and fellow guitar greats Steve Vai and Zakk Wylde will front next year's annual Rock 'n' Roll Fantasy Camp in L.A.
in Music
Stevie Wonder is a single man
The "Sir Duke" singer, separated from his second wife since 2009, is officially divorced.
in Music
Giant human peace sign celebrates Lennon's 75th
More than 2,000 people joined Yoko Ono in New York's Central Park in an attempt to set a world record for the largest group of people forming a peace sign.
Vin Diesel fuels rumors F. Gary Gray is directing 'Furious 8'
The "Straight Outta Compton" moviemaker has emerged as a frontrunner to take over the blockbuster franchise.
in Trending, Viral Videos
TODAY'S MUST SEE: 'Jaws 19' trailer
It's the movie that "Back to the Future II" promised us we'd see in 2015.


text: Chris Evans 5/09/13 Why You Should Like Chris Evans Read More Chris Evans Chris Evans Chris Evans and Hayley Atwell's Reaction to This Surprise Proposal Is Priceless Not Even the Avengers Can Keep Their Cool in This Age of Ultron Blooper Reel A Very Handsome Look at Chris Evans's 15 Years in the Spotlight Sexy Stars Named Chris Are Stealing the Hollywood Spotlight POPSUGAR, the #1 independent media and technology company for women. Where more than 75 million women go for original, inspirational content that feeds their passions and interests. Be in the Know With OurCelebrity and Entertainment Newsletter Personalize A-Listers Young Hollywood Movies TV Sign up with facebook or By signing up, I agree to the Terms and to receive emails from POPSUGAR.


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Reuters - Sun, 07 Mar 10:15:00 2010
Japan's Ai Miyazato was denied a hat-trick of victories to start the season after South Korean Ahn Sun-ju won the Japanese LPGA curtain-raising Daikin Orchid Ladies in Okinawa.
Miyazato (pictured), who won her first two events of the season in Thailand and Singapore, carded a 72 in the final round to finish on three under.
Ahn marked her Japanese debut in style, firing a five-under-par 67 to finish on 10 under, a winning margin of five strokes over compatriot Shin Ji-yai.


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Ooo, angsty and dramatic- I love it! I love your symbolism with the candle and all the foreshadowing. And how sweet with Telmacar and his son! Something tells me this won't end well, but I look forward to reading more, anyway!
Oh, no, you killed Pippin!!!! (Of course, life's not going so great for him in my story, either, so I guess I'm not really one to talk). This is good. I like the part where Faramir talks to the tree as a symbol of his brother. Keep it up, and I look forward to your said more emotional chapters!
Author's Response: Thank-you, Traveller! I am glad you like it. I shall be posting more chapters soon. (I am currently working on chapter 5).
Very thought-provoking AU story. Kind of scary to think about too, but nevertheless intriguing. I love it, but there could be some more emotion in it for people (like me! ;-) ) who thrive on reading angsty stories. However I do love this and hope to read more of your works!
Author's Response: Thank-you! At first I thought this fanfic wouldn't work too well. (It is my first shot at an AU. Don't you worry, there are going to be some good emotion coming soon! Shall be posting the other chapters soon. (I am currently working on chapter 5). Thank-you again for reading!


text:
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Thanks for helping us associate the correct Pornstars to this video!
Aiutaci: queste pornostar appaiono in questo video?
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Tutti i commenti (17)
who of the girls want to be fucked like this? pm me =)
I want to be screwed up by three guys... wow i would love to take 3 hot dicks in my holes..
every mans dream double pussy fucking and one in her ass to rub against !!
couldn't get off watching this because the audio is so ridiculous
lollerz.turn your audio off.anyway i would love to have those young men cum on my face and in my mouth.thier cum looks so tasty.
very good
damn that looks like the most pleasure a woman can have
OMG. That;s my dream!!!!!!!!!!!!!!!!!
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this reminds me of a scene you might find in hell - complete with german dubbing and happy background music....
Omigawd! Triple penetration!~


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