text:
Air Fest Postponed
Due to the gloomy weather forecast, the Air Fest event at Maryville College has been postponed from Saturday, April 14, to Saturday, April 28, from 5 pm-8 pm.
So see ya on the 28th ( not tomorrow!) at the Blount County AirFest.
Come on out. Ask EHAT- Blount County Environmental Health Action Team about the work it has done in the past. They have done studies on what we as Blount County residents want for our county. Ask them about those concerns because there has been very little coverage on this.
You might even want to read about it before you go.
The Harvey Broome Group Sierra Club will be there. Ask them about mountain top developments and these new fangled onsite wastewater systems that are changing the face of our mountains and wetlands.
Come on out, ask questions and question all the answers.
That was one of the many lessons of Watergate. Now, as I'm sure you've heard, there is yet another revelation regarding the U.S. Attorney firings investigation reminiscent of the "18 minute gap":
The investigation has revealed that White House e-mails about official business — on electronic accounts intended for political matters — may be gone, in violation of a law that requires their preservation. Twenty-two White House officials, including political adviser Karl Rove, have the accounts sponsored by the Republican National Committee, administration officials say.
White House spokesman Scott Stanzel on Thursday could not rule out that some of the missing e-mails involved the attorney firings.
John Conyers, Chairman of the House Judiciary Committee, has requested all of the RNC e-mails pertaining to the U.S. Attorney firings, but they have yet to comply. Conyers says "The White House position seems to be that executive privilege not only applies in the Oval Office, but to the RNC as well."
The RNC claims that prior to 2004 they had a policy to automatically purge e-mail archives on a regular basis. Senate Judiciary Committee Chairman Patrick Leahy is skeptical: "They say they have not been preserved. I don't believe that!"
Citizens for Responsibility and Ethics in Washington says there are more than five million missing e-mails, a violation of federal law.
It does seem odd that there are no backups. Republicans are supposed to be well-versed in Business 101 matters such as records retention and IT business continuity best practices and compliance audits and all that stuff. And weren't the personnel actions in question more recent than 2004?
But what's really puzzling about all this is that there's no real evidence that anyone has done anything illegal with regard to the U.S. Attorney firings. It's pretty well established that Bush is politicizing the Justice Department, but that's not necessarily a crime, is it?
So why the cover-up?
Hello- my name is Cameron Brooks and I am an organizer with the Communications Workers of America.
I work for a union here in Knoxville called United Campus Workers. We are an organization of UT Faculty and Staff working to improve conditions for employees at the university. We are in the midst of pushing for a decent pay raise this year and have an email action alert campaign that we wanted to share with Knoxviews- here is a link to the action alert:
UT employees have languished under less than decent pay raises over the past decade. Additionally, there is a huge problem with UT paying poverty wages. Please join with us in addressing this issue.
In Solidarity,
Cameron Brooks
State Sen. Tommy Kilby (D-Oakdale) reminds us of an upcoming sales tax holiday, Friday April 27th through Sunday April 29th. This is a special one-time exemption for 2007 in addition to the usual August sales tax holiday. More details at www.tntaxholiday.com.
WBIR has an interactive map showing the current and proposed school zones. You can enter your address and see how you will be affected. Click on the little round symbols to see the name of the school zone. The right column has settings for current and proposed zones.
Big Trouble: Solving Education Problems Means Rethinking Super-Size Schools and Districts. Focus on Utah. link.
does this sound familiar?
Abstract: Big school districts promised to hold down costs by centralizing functions under one roof and delivering a greater selection of academic offerings and activities, thus improving education. But they have not delivered. Up to a certain size, consolidation can save costs, but above that size, districts experience "diseconomies of scale," including misallocation of funds toward bureaucracy rather than instruction. On average, large districts' standardized test scores fall in the lower end of their expected ranges, while smaller districts' scores fall in the upper end of their ranges. Large schools are concentrated in large districts, and big schools experience the same problems as big districts. Parents are not happy with big districts--their complaints over test scores, curriculum, taxes, or anything else always come back to the issue of control. In a big district, the bureaucracy makes the important decisions, and parents feel alienated. Some districts have tried to create sub-schools that share a common school building or to create sub-districts or local councils, but they fail to address the issue of control. If administrators don't deal with the problem, frustrated citizens will take their complaints to the state, which will attempt to force quality. Limiting the size of districts and schools and creating smaller districts will improve academics and efficiency and encourage public participation by bringing issues back to the local level. This will spur innovation, flexibility, and commitment by parents and teachers.
This afternoon at work, a co-worker came up and said, "I'd like to introduce you to someone who's going to be doing some work for us." It was Rocketsquirrel. She said to Rocketsquirrel, pointing to me, "He also posts at KnoxViews."
Rocketsquirrel: "Oh, cool! ... Uh ... wait ... you aren't #9, are you?"
Me: "God, no."
via WBIR
I'm very surprised that more attention hasn't been given to a possible failure of the Wolf Creek Dam. This could be catastrophic on a NO Katrina scale. Check out Davidson County. I hope any of you guys living in the inundation zones have flood insurance and a "get the hell out of Dodge" plan. According to the US Army Corps of Engineers the estimated damage in case of a failure is over $3 billion in damages...not to mention the possible loss of lives.
Link to view all maps here
CBS to permanently cease broadcast of Imus in the Morning, effective immediately.
The Tennessee Alliance for Progress is having it's fourth annual conference this weekend:
The Compass IV Conference will be held April 13-14, 2007 at the Cohn Adult Learning Center in West Nashville. This two-day gathering of progressives from around the state will feature networking, workshops, skill trainings, films, live music, the TAP Long Haul Awards and Silent Auction plus other events. This is THE statewide progressive gathering of the year in Tennessee. You don't want to miss it!
David Sirota, author of Hostile Takeover, and Paul Waldman, author of Being Right is Not Enough, will be keynote speakers.
We wanted to go this year, but real life and work related program activities intervened. If you're in the area, or up for a short drive to Nashville, it would be well worth your while to attend. Follow the links above for program and registration info.
Unfortunately, many parents and students will look at the KCS rezoning plan from a neighborhood, or personal, point of view.
What is at stake here is larger. It is about quality of education for all of our students enrolled in public school.
Large megaschools are not as effective as smaller schools. So says the research, including the ground-breaking book, "High Schools on a Human Scale: How Small Schools Can Transform American Education."
Microsoft billionaire Bill Gates and his wife Melinda have a foundation that has committed more than $400 million in the past three years to making American high schools smaller, according to the Washington Post.
But unfortunately, Knox County only approaches these issues from an infrastructure and growth planning issue, not from the perspective of valid educational benefit to the students.
We have one high school in Knoxville sitting empty (Rule) while a new one is being built (Hardin Valley). We have growth throughout the county. Rule sits on only 7 acres of land, thus excluding it from consideration under the megaschool paradigm that is reflected in the leadership within the Knox County School System.
Using simple reasoning, if we have growth throughout the county, one megaschool built every 10 or 15 years will result in catastrophic rezoning every 10 or 15 years.
Do we want to shift 20% of our student population every 10 years, or do we want to bring the resources to their communities? That is the fundamental question.
The alternative: Build more, smaller, cheaper schools throughout the ever-growing Knox County, better personalizing the educational experience.
According to the author, several studies show "that high schools are more likely to be successful when they are small and personalized -- when they have four to five hundred students and stress long-term relationships between students and teachers, individualized attention, extra help for struggling students, and an adult advocate for every student. Smaller schools encourage stronger bonds between students and teachers and generate a level of genuine caring and mutual obligation between them that's found far less frequently in comprehensive high schools."
"Students and teachers, as a result, tend to work harder on each other's behalf. Student and teacher attendance and student involvement in extracurricular activities are higher in smaller high schools. Teacher turnover and disciplinary problems are lower. So are dropout rates. There's less tracking in smaller schools. And a wide range of studies reveal that average student achievement is as high as and often higher than that in large schools, particularly among students from impoverished backgrounds."
Sad Day for Sevier County
By James J. Wilson
The Cove Mtn. project (High Bridge PUD) was approved by the Sevier County Planning Commission (PC) last night by a 7 to 4 vote.
There were many questions about the legality of the documents the developer (Kenneth Whaley, also a county commissioner) submitted.
Specifically, the developer presented a 1971 deed that just turned up yesterday that, they say gives them the 50 foot Right of Way (ROW) necessary to access their project.
You may recall that the PC voted to deny this same permit last month because of just that ROW question.
There was an overflow crowd waving signs and being very vocal, as you might imagine. Both commissioners from the district that this PUD is forced upon were pleading with their fellow commissioners to defer the vote until such time that the legality of the documentation could be verified.
Remember that this same commissioner, Kenneth Whaley and his partners at Southern Design are the same ones whose last PUD went belly up and has left scars across Webb Mountain that is causing severe erosion of a pristine waterway even today.
The commissioners had a motion (and second) on the table with a recommendation for approval from the County Planer, Jeff Owenby, before they accepted any public comments.
Five people spoke against the project and raised many questions.
The County Planner did not choose to amend his recommendation and it was hastily passed.
(more after the break)Continued...
I posted this to Reality Me but it should have been posted here to reach the masses. As a reminder, if you do not have children, this decision by the school board could impact your property value. If you have young children, they will be in high school sooner than you think, and this rezoning will likely be a model for the middle school and elementary rezoning which will follow soon.
On Aug 3 2006, Sam Anderson ran unopposed for the School Board 1st District, Dan Murphy ran unopposed for the School Board 4th District, Thomas A Deakins beat H Lee Martin by 372 votes for the School Board 6th District, Rex Stooksbury ran unopposed for the School Board 7th District, and Robert Bratton ran unopposed for the School Board 9th District. I am not sure about the other districts.
According to two commenters on No Silence Here, at least one school board member's neighborhood seemed to escape rezoning. (can anyone verify this? are there others?)
Isn't it amazing that Karen Carson's neighborhood and surrounding neighborhoods are no longer in the rezoning area????????? Hmmmmmmmmmmm. Gee, what a coincidence. [Source]
I noticed that Chairwoman Karen Carson's neighborhood did not get rezoned to either Bearden or Hardin Valley even though the area is sandwiched between those being rezoned. Just curious if any school board members' neighborhoods are being rezoned? [Source]
Are we, the people, being properly represented by our elected officials or have these elected officials found an easy way to serve their own best interests? Seems to me that if I had the foresight to want to greatly influence this rezoning that I should have simply run for the School Board. If the majority of the people do not want this rezoning approved and it happens anyway, then the democratic process is failing and we, the people, need to remove the elected officials from their duties and replace them with officials that will better represent the people's wishes.
Now we beg the question, what does the majority want?
A bomb exploded in the Iraqi parliament's cafeteria in a stunning assault in the heart of the heavily fortified, U.S.-protected Green Zone Thursday, killing at least two lawmakers and wounding 10 other people.
GOP presidential candidate Sen. John McCain has not commented on this latest example of how safe it is in Baghdad.
That's what this otherwise well-written and well-researched editorial in the student run Tennessee Journalist says regarding victims of computer virus attacks. The comments are uh, interesting, too.
A Tennessee blogger is being threatened with a lawsuit by a job placement outfit over a post she made about her and her husband's experience with them. Nashville is Talking has the background and a roundup. Newscoma has an extensive catalog of links.
Free speech does not mean freedom to libel, but...Continued...
Breaking news out of Alabama about an amazing new technological discovery:
Some of Alabama's nastiest coal-fired power plants may be cleaning up their act with some new technology called a "scrubber" that was unveiled by Alabama Power Company executives Wednesday.
The mechanism, expected to be operational in 2008, is designed to strip some of the worst pollution out of power plant emissions.
Dangerous sulfur dioxide, called SO2, is stripped from the plant's emissions through a scrubbing process that works like a shower. Pollution is mixed with limestone powder and water, which strips gases out of the plant's emissions before they're released into the air.
Wow, I wonder if TVA has heard about this new "scrubber" technology?
Wait a second. This sounds familiar. Oh, yeah, now I remember:
Most modern power plants — and all plants built after 1978 — are required to have special devices installed that clean the sulfur from the coal's combustion gases before the gases go up the smokestack. The technical name for these devices is "flue gas desulfurization units," but most people just call them "scrubbers" — because they "scrub" the sulfur out of the smoke released by coal-burning boilers. [..]
In most scrubbers, limestone (or another similar material called lime) is mixed with water and sprayed into the coal combustion gases (called "flue gases"). The limestone captures the sulfur and "pulls" it out of the gases.
Maybe the mule train hauling the mail got waylaid by bandits and the news about this technology has just now reached Alabama.
But seriously, it's hard to say which is worse -- Alabama Power Company executives trying to suggest this is "new technology" when in fact they should have installed it 30 years ago, or a "senior TV news reporter" who just transcribes what they say without bothering to check it out.
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text:
Release Date:
May 1, 2009
Date Published:
May 1, 2009
The V W Golf was planned to be a worthy successor to the venerable Beetle, a move that required dynamic thinking and a clean drawing board if Volkswagen was to continue to hold its position at the nucleus of top motor manufacturers.
Genre: Transportation
Sub-Genre: Automotive / Pictorial
- Genre: Transportation
- Subgenre: Automotive / Pictorial
- Publisher: Crowood Pr
- Pages: 208
- Language: English
- Author: James Richardson
other Info.
- Online Item #: 12202848
- Store Item Number (DPCI): 248-41-1889
- Item can be gift wrapped.
- Made in the USA or Imported

subset: commoncrawl


text:
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text:
BOSTON — The Boston Celtics gave the Miami Heat all they could handle before the Heat managed to escape with a 105-103 win.
The C's have plenty of positives to take away from the loss.
But that means nothing to this team, not after having been in control for the better part of three quarters, only to allow LeBron James and company to steal the victory in the game's closing seconds.
"I told our guys, 'that was our first playoff game, for a lot of the new guys," Rivers said. "And I was really looking forward to the game because I didn't know how a lot of guys were going to react. Besides not winning the game we passed the test."
Try telling that to Paul Pierce who had 17 points but failed to make a 3-pointer in the final seconds that would have put the C's on top and potentially been the game-winner.
"We feel like we match up with them, top to bottom," Pierce said. "But you know, like I said, no moral victories."
For Rivers, the game was decided well before James' game-winning jumper over Green with 10.5 seconds to play.
"As hard as we played, and we played great ... I just thought we made too many mistakes defensively switching, and giving up lay-ups," Rivers said. "Overall, I'd take the game. It was a fantastic game. I just don't like losing it."
Added Pierce: "There's always positives from every game. It's always gonna come down to the little things, and those little things really add up at the end of the day when you have a two-point loss."
Here are some other factors outlined prior to the game, and how they impacted the game as the Celtics embark see their season-best 11 game winning streak at home come to a screeching halt by the Heat.
WHAT TO LOOK FOR: Despite having lineups filled with high-scoring talent, both of these teams have hedged their bets for success on stout defense. When the two played back in January, the Celtics won 100-98 in double-overtime. Look for points to be hard to come by for both teams once again.
WHAT WE SAW: The offenses for both teams were humming along Monday night, especially the Celtics who spent a good chunk of the game shooting better than 60 percent from the field. In the end, the Celtics made 54.2 percent of its shots while the Heat shot 49.4 percent from the field.
MATCHUP TO WATCH: Avery Bradley vs Dwyane Wade: Bradley and Wade have been a huge part of their respective team's success of late, with Bradley contributing with his defense and timely shot-making while Wade has been getting it done at both ends of the floor as well.
WHAT WE SAW: Bradley did a decent job defensively on Wade as he scored 16 points while taking 15 shots from the field. But down the stretch, Wade's rebounding was huge. He grabbed five of his seven rebounds for the game in the fourth quarter. To put that in perspective, the C's had a total of just six rebounds in the fourth.
PLAYER TO WATCH: Jeff Green is indeed an X-factor for the Celtics. At the very least, Green needs to score in double figures as well as make his presence felt defensively. Although he only had 11 points in Boston's win over the Heat on Jan. 27, the Celtics were plus-6 with him on the floor which was the second-highest plus/minus ratio for any Celtics players (Paul Pierce, plus-8).
WHAT WE SAW: Green had the best game of his life, scoring a career-high 43 points to go with seven rebounds two assists and four blocked shots. "He had a tremendous game," said Heat coach Erik Spoelstra. "He played great, he was aggressive, he was making tough plays, and he was putting a lot of pressure on our defense."
STAT TO TRACK: The Celtics' success since the all-star break has been fueled in part by the increased scoring of the C's bench. For the season, the Celtics rank 15th in the league in bench scoring. But since the break, they are now 10th with a 35.2 bench points scored per game. In the C's triple overtime win against Miami on Jan. 27, Boston's backups outscored Miami's second unit, 39-29.
WHAT WE SAW: Bench scoring was not a huge factor in Monday's game, in part because of the key players for the Celtics' second unit - Jeff Green - was starting in place of an injured Kevin Garnett. Even with Green's production out of the equation for the backups, Boston's reserves still outscored their Miami counterparts, 17-16.
Celtics - Heat review: No moral victories for C's
BOSTON — The Boston Celtics gave the Miami Heat all they could handle before the Heat managed to escape with a 105-103 win.


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APM Terminals confirmed its interest in expanding its presence in Mexico as it starts the countdown to the opening of a container terminal at the port of Lazaro Cardenas on the country's Pacific coast.
Press Releases
29 May 2015
The value of goods trucked across the U.S.-Mexican border is outpacing the number of trucks making the crossing, rising twice as fast, U.S. transportation and trade data show.
29 May 2015
International Container Terminal Services Inc. has agreed to pay $54.5 million to acquire Mexican port operator Terminal Maritima de Tuxpan.
26 May 2015
The truck leasing arm of Paccar plans gradual expansion across Australia as shippers and carriers replace the nation's aging heavy trucks and 'road train' tractors.
22 May 2015
Mexican exports this year are set rise 5 percent on increased demand for automobile shipments and other manufactured goods built in Latin America's second-largest economy.
21 May 2015
In a deal expected to close on Aug. 1, Scarbrough International, a Kansas City-based logistics and customs brokerage firm, will expand its operations south and into Mexico.
18 May 2015
The number of tractor-trailers crossing U.S. borders rose 2.4 percent in the first quarter, following a 4 percent increase last year, according to Department of Transportation data. Border crossings between the U.S. and Mexico outpaced U.S.-Canadian truck traffic.
12 May 2015
The fastest-growing port in North America in 2014, with 13.8 percent year-over-year growth, was Prince Rupert, British Columbia. Its Fairview Container Terminal was recently acquired by DP World. With 11.23 percent growth, Mexico's Pacific port of Manzanillo edged out Boston, at 11.20 percent growth, for the No. 2 spot.


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Lung cancer most often presents as an inoperable tumour and the diagnosis is usually performed on a small biopsy/cytology specimen. In the group of non small cell lung cancer - not otherwise specified, adenocarcinoma phenotype can be determined immunohistochemically using TTF-1 and Napsin A. Expression of oncofetal protein IMP3 in human cancer is associated with poor differentiation and aggressive behaviour. In the present study expression of IMP3 was correlated with expression of TTF-1 and Napsin A, histological subtype and clinical stage of lung adenocarcinoma. We were interested whether distant metastases are associated with IMP3 overexpression, regardless of the histologic subtype of adenocarcinoma.
In retrospective study, consecutive series of 105 patients with advanced lung adenocarcinoma diagnosed from 2006 to 2009 in Clinical Hospital Center Split, Croatia, were analysed. Clinical data were collected from the Pulmology Department and time of death from the Mortality Registry. Paraffin blocks of bronchoscopic biopsies were collected from the Institute of Pathology and 15 cases excluded from the analysis due to insufficient material. Expression of IMP3, Napsin A and TTF-1 were analysed by indirect enzyme immunohistochemistry. Statistical analysis was performed and P values less than 0.05 considered significant.
Of 90 patients, 71 (78%) were males and 19 (22%) females. Median age for males was 61.5 years (min-max 43–83) and for females 61 years (min-max 44–86). Pleural effusion was found in 15 (16.6%) and distant metastases in 45 (50%) cases. According to histological subtypes, there were 34 acinar, 2 lepidic, 2 papillary and 52 solid subtypes. IMP3 overexpression was found in 63 cases (70%) and was correlated with solid subtype (P=0.002) and negative/weak Napsin A expression (P=0.004). Strong Napsin A expression correlated with TTF-1 expression (P=0.003) and lower histological grades (P=0.031). Patients with IMP3 overexpression more often had distant metastases than patients with negative IMP3, 55.5% versus 33.3% (P=0.033). Non solid subtypes with IMP3 overexpression developed distant metastasis more common than non solid subtypes with negative IMP3, 72% versus 35% (P=0.028).
Expression of IMP3 correlates with solid subtype and with distant metastases regardless of histological subtype of lung adenocarcinoma.
Das Lungenkarzinom kommt meistens als nicht resektabler Tumor vor und die Diagnose kann nur in kleinen Biopsaten oder zytologisch gestellt werden. In der Gruppe der nicht kleinzelligen Lungenkarzinome kann der nicht anders spezifizierte Adenokarzinom Phänotyp mit Hilfe der Antikörper TTF-1 und Napsin A diagnostiziert werden. Die Expression des onkoföetalen Proteins IMP3 ist bei humanen Karzinomen mit agressivem Verhalten und metastatischem Potential verbunden. In dieser Studie korreliert die Expression von IMP3 mit TTF-1, Napsin A, histologischem Typ und klinischem Staging des Lungenkarzinoms. Wir waren daran interessiert, ob Fernmetastasen mit IMP3 Überexpression assoziiert sind, unabhängig von der histologischen Subtyp von Adenokarzinom.
In der retrospektiven Studie wurden die von 2006 bis 2009 im Klinischem Krankenhaus Split, Kroatien diagnostizerte Adenokarzinome der Lunge von 105 Patienten analysiert. Die klinischen Daten stammten aus der Abteilung für Pulmologie und im Falle des Todes vom Todesregister. Die Paraffinblöcke der primären Lungenbiopsate dieser Patienten wurden im Institut für Pathologie mit der indirekter Enzym - Immunohistochemie mittels Kombination der Antikörper gegen IMP3, Napsin A und TTF1 untersucht. 15 Fälle aus der Analyse aufgrund unzureichender Material ausgeschlossen. Es wurde eine statistische Untersuchung durchgeführt und Werte weniger als 0.05 P wurden als statistisch signifikant bezeichnet.
Von 90 Patienten mit Lungencarcinom waren 71 (78%) mänlich, durchschnittliches Alter war für Männer 61.5 Jahre (min-max 43–83) und 61 Jahre für Frauen (min-max 44–86). Pleurale Effusionen fand man in 15 Fällen (16.6%) und Fernmetastasen in 45 (50%) Fällen. Histologische Sybtypen waren: 2 lepidic Karzinome, 34 azinäre Karzinome, 2 papilläre und 52 solide Karzinome. IMP3 war exprimiert in 63 Fälle (70%). Positive IMP3 Expression war mit solidem Typ (P=0.002) und negativer Napsin A Expression (P=0.004) assoziert. Napsin A Expression war mit niedrigem Gradus (P=0.031) und positiver TTF-1 Expression (P=0.003) assoziert. Patienten mit IMP3 Überexpression öfter hatten Fernmetastasen als Patienten mit negativen IMP3, 55.5% versus 33.3% (P=0.033). Non solide Subtyp mit IMP3 Überexpression entwickelten Fernmetastasen Meer häufiger als nicht festem Subtyp mit negativen IMP3, 72% versus 35% (P=0.028).
Die Expression von IMP3 ist mit negaativer Expression von Napsin A, solidem Subtyp und Metastasen verbunden und hat praktische predictive Werte in der pathologischen Diagnose des Adenokarzinoms der Lunge. Die Expression von IMP3 korreliert mit soliden Subtyp und mit Fernmetastasen unabhängig von histologische Subtyp Lungenadenokarzinom.
Lung cancer is the leading cause of cancer mortality in the world, with the highest incidence in the Western World and poor overall survival [1]. It presents a complex disease with different phenotypes, variabile responses to therapy and probably different relationships to specific carcinogens [2]. Small cell lung carcinomas (SCLC) and non-small cell lung carcinomas (NSCLC) are wide and clinically relevant groups of lung cancer. The most common histologic type of NSCLC is adenocarcinoma (ADC), accounting for nearly half of all lung cancers [3]. There is general agreement that squamous cell carcinoma (SCC) and SCLC have the highest accuracy of diagnosis in small preoperative specimens, whereas ADC is less accurately diagnosed due to its histological complexity [4]. Due to advanced clinical stage at presentation, up to 90% of diagnoses are established on small biopsy or cytology specimen [5], but because of the paucity of bronchoscopic material, careful selection of ancillary methods (like histochemical mucin stain, immunohistochemistry and polymerase chain reaction) should be done [6]. Multiplex panel dual immunohistochemistry using p63/CK 5 and TTF-1/Napsin A are useful in subcategorising NSCLC-NOS into SCC and ADC phenotypes [7]. Combination of TTF-1 and Napsin A highly improved sensitivity and specificity for diagnosing lung adenocarcinoma [8]. TTF-1 is a nuclear tissue-specific DNA-binding protein mainly expressed in thyroid follicular cells, type II pneumocytes and nonciliated bronchiolar epithelial cells. Its function in lungs is transcriptional activation of surfactant proteins and secretory proteins of Clara cells [9]. Napsin A is aspartic proteinase involved in the maturation of the surfactant B. It is expressed in the cytoplasm of type II pneumocytes and Clara cells, in proximal tubular renal epithelium and exocrine pancreas [10,11]. In the last few years IMP3, member of insulin-like growth factor II mRNA binding protein family, was investigated in different malignant neoplasms because its overexpression is generally associated with aggressive and advanced tumours [12]. Normally, IMP3 is expressed in developing tissues during embryogenesis and plays the role in RNA trafficking and stabilisation, cell growth and migration [13]. In adult tissues IMP3 expression is low or undetectable, but in malignant tumors is strongly expressed [14,15]. In most studies increased expression of IMP3 correlates with aggressive biological behaviour of the tumour [16,17]. Expression of IMP3 in series of lung cancer was analysed in few studies. According to these articles, IMP3 overexpression in high grade neuroendocrine carcinoma [18], non small cell lung carcinoma [19] and adenocarcinoma [20] correlated with poor differentiation and advanced stage of disease. In this study we analysed expression of IMP3 in histological subtypes of lung adenocarcinoma and its impact on clinical staging.
From January 2006 till December 2009, 807 new cases of lung cancer were diagnosed at the Institute of pathology, forensic medicine and cytology, Clinical Hospital Center Split, Croatia. The consecutive series of 105 patients with primary inoperable adenocarcinoma were investigated. Clinical data (age, sex, tumor size, clinical staging) were collected from the hospital records and time of death from the Mortality Registry. Overall survival was evaluated for outcome analysis. Paraffin blocks were collected from the Institute of pathology, forensic medicine and cytology and 15 cases were excluded due to insufficient material. Indirect immunohistochemical analysis was performed on 5-μm sections using primary monoclonal mouse antibodies against IMP3 (dilution 1:200), Napsin A (dilution 1:200) and TTF-1 (dilution 1:100), EnVision/HRP and chromogen 3,3'-diaminobenzidine (all reagents DAKO, Glostrup, Denmark). The slides were analysed with light microscope Olympus 51BX by two pathologists. Diffuse cytoplasmic staining for IMP3, nuclear staining for TTF-1 and granular cytoplasmic staining for Napsin A were considered positive. Expression of TTF-1 and IMP3 was assessed as positive or negative and expression of Napsin A as negative/weak or strongly positive (Figure (Figure1).1). Cases with more than 10% of positive cells were considered as positive. Statistical analysis was performed using the SPSS 19 system for Windows and P value less than 0.05 was considered statistically significant.
In the sample were 90 patients, 71 (78%) males and 19 (22%) females. Median age for males was 61.5 years (min-max 43–83) and for females 61 years (min-max 44–86). In five years of follow up, 79 (87%) patients died. The mean overall survival was 8 months (95% CI 1–34 months). Median survival was 2,5 times longer in patients without distant metastases: 9 months (SE 1.8 months) (95% CI 5.4-12.6) compared to patients with metastases: 4 months (SE 1.1) (95% CI 1.9-6.1) (log rank 6.5 P = 0.011). The pleural effusion was present in 15 (16.6%) cases and in 14 patients was cytologically malignant. In the beginning of diagnostic procedure 19 patients were examined with multislice computed tomography of the thorax and upper abdomen and staged into T2 (5), T3 (7) and T4 (7) categories; the remaining patients only had chest radiography. Median tumour size was 58.5 mm (min-max 21–112). Radiographic evidence of significantly enlarged and presumably positive regional lymph nodes had 51 (56.6%) patients. In the analysed period 45 (50%) patients developed distant metastases in bones (14), brain (10), liver (5), adrenal glands (4), or multiple sites (12). Histological grading was performed according to the presence of solid component and cytological atypia [21], resulting in 18 well differentiated, 23 moderately differentiated and 49 poorly differentiated tumours. According to the criteria set forth by the WHO (2004), there were 34 acinar, 2 lepidic, 2 papillary and 52 solid subtypes; in further analysis solid subtype has been compared to others.
According to Table Table1,1, positive expression of IMP3 was found in 61 (67.7%) cases. Median age of patients with positive IMP3 expression was 58.5 years (min-max 43–83) and of patients with negative IMP3 expression 63 years (53–79) (Z=1,75 P=0.08). Median tumor size was 58.5 mm (min-max 21–112) in IMP3 positive patients and 60 mm (min-max 22–108) in IMP3 negative patients (Z=0.82 P=0.411). No statistically significant correlations were observed with sex (χ2 =0156 P=0.693), pleural effusion (χ2=3.5 P=0.063), histological grade (χ2 =2.499 P=0.287) and TTF-1 expression (χ2 =0.276 P=0.599). Overexpression of IMP3 correlates to solid subtype (χ2 =9.4 P=0.002) and negative Napsin A expression (χ2 =8.25 P=0.004). In the group of 52 cases with solid subtype, 43 (82.6%) had IMP3 overexpression and in the group of 38 cases with other subtypes 20 (52.6%). IMP3 overexpression correlated with presence of distal metastases (staging M1b) (χ2=6.844 P=0.033).
Table Table22 shows the distribution of metastases according to IMP3 overexpression in patients with non solid subtype of adenocarcinoma. Among 18 patients with distant metastases, 13 (72%) were IMP3 positive. Among 20 patients without distant metastases, IMP3 was positive in 7 (35%) cases. In non solid subtypes, IMP3 overexpression was more often found in patients who developed metastasis (Fisher exact test P=0.028). IMP3 positive cases had shorter time of overall survival, but result is not statistically significant (log rank 0.14 P=0.713). Patients with negative IMP3 expression had mean survival 9 months (SE 2 months) (95% CI 5–12 months) and patients with positive IMP3 had mean survival 9 months (SE 1 month) (95% CI 4–6 months).
Expression of Napsin A was not related to sex (χ2 =1.577 P=0.209) and pleural effusion (χ2=0 P=1). In cases with negative expression of Napsin A median tumor size was 59 mm (min-max 23–112) and with positive Napsin A expression 59.98 mm (min-max 21–108) (Z=0.518 P=0.605). Napsin A expression correlated with TTF-1 positivity (χ2=8.986 P=0.003) and lower histological grade (χ2=8.986 P=0.003).
About 70-80% of lung carcinomas fall under the classification of NSCLC with adenocarcinoma as the most common subtype [22]. In the past, all subtypes of NSCLC received the same therapy and subclassification was not important for the treatment or prognosis. Recent development in the treatment strategies necessitates further cytological and histological subtyping of NSCLC. Promotor methylation was more common find in squamous carcinoma and correlated to pleural indentation [23]. Activated gene mutations are more common found in adenocarcinoma [2]. New biologically targeted chemotherapies, such as bevacizumab, have clinical benefits in patients with ADC, but strong contraindications in SCC cases. There are therapies that target EGFR mutations and ALK fusion genes which are found almost exclusively in adenocarcinomas. Architecture of pulmonary adenocarcinoma is very heterogeneous. Morphologic features, as specified in the WHO classification 2004, have been the standard for NSCLC subtyping, but according to Terry et al. [7], 25% of bronchoscopic biopsies cannot be subclassified by morphology alone so immunohistochemical and/or genetic analyses are necessary. Immunohistochemical markers TTF-1 and Napsin A are nowadays a useful tool in adenocarcinoma identification and their dual use improves diagnostic accuracy, but does not give us data about prognosis of cancer which often has high metastatic potential. There have been some studies about prognostic value of some histological characteristics [9,21] or methylation markers [23]. We tried to obtain this important prognostic information using antibody to oncofetal protein IMP3, previously identified as a marker of aggressive behaviour in various tumours.
Expression of IMP3 was analysed in relation with histological grade proposed by Barletta et al. [21], but no significant correlation was found (P=0.287). According to some authors, [24] there is no well-established histological or cytological grading scheme for NSCLC and currently applied subjective grading is not prognostically relevant. In our series solid subtype was the most common and it was analysed in relation to other subtypes (acinar, lepidic and papillary) grouped together. One case of papillary subtype had characteristics of recently described stromal micropapillary pattern [25,26]. IMP3 overexpression correlated with solid subtype (P=0.002). In the series of 89 surgically resected specimens Findeis-Hosey et al. have found that positive IMP3 expression was strongly correlated with poorly differentiated adenocarcinoma and solid component of myxed subtype adenocarcinoma [20]. In our study, expression of TTF-1 and Napsin A were 61% and 51%, respectively. TTF-1 expression value was within reported range [9], but percentage of Napsin A positive cases was surprisingly low [27]. Possible explanation for this could be high proportion of solid subtype in our series, although technical problems in sampling and fixation could not be excluded. Expression of Napsin negatively correlated with poor differentiation and 40 (76.9%) cases of histologic grade 3 were Napsin A negative (P=0.031). Expression of TTF-1 did not correlate with grade (P=0.542), which confirmed objection of Ueno et al. [27] that TTF-1 showed no association with the grade of tumour differentiation. Both TTF-1 and Napsin A were negative in 28 cases, majority of those were of solid subtype and immunohistochemically negative to Cytokeratin 5/6. The proportion of dual negative cases in our study was higher than in study of Turner et al. [8], 32% versus 10.6%, respectively which could be explained by high percentage of solid subtype in our sample. IMP3 overexpression correlated with negative expression of Napsin A (P=0.004), but correlation of IMP3 and TTF-1 was not found (P=0.599).
During five-year follow-up, out of 90 patients with inoperable lung adenocarcinoma, 79 (8.77%) died. The mean overall survival was 8 months (95% CI 1–34 months). IMP3 overexpression had no influence on mean overall survival (P=0.712). We did not find statistically significant difference in tumour size (P=0.411), T staging (P=0.458) or N staging (P=0.612) among IMP3 overexpressed and IMP3 negative cases. Findeis-Hosey et al. found that IMP3 is more frequently expressed in larger tumours with positive lymph nodes or higher clinical stage, but the difference was not statistically significant [20].
In our series, 45 patients developed distant metastasis to the brain, liver, adrenal glands, bones or to multiple sites. Quite often symptoms of metastases were the first sign of the malignancy. IMP3 overexpression showed correlation with distant metastases regardless of histological subtype (P=0.033). Further series are needed to confirm these results and eventually establish IMP3 in initial immunohistochemical panel for small bronchoscopic biopsy/cytology, as a marker for aggressive behaviour and higher metastatic potential of lung adenocarcinoma.
In conclusion, IMP3 overexpression correlated with solid subtype and negative expression of Napsin A, as well as distant metastasis regardless of hystological subtype. Our results confirm that positive IMP 3 expression predicts aggressive tumour behaviour in lung adenocarcinoma and can be used as a significant predictor of unfavorable outcome.
The authors declare that they have no competing interests.
RBP and MGD designed the study, analysed histological slides, interpreted the results and drafted the manuscript, AP, VI and MP collected pathological, clinical and radiological data, VC performed the statistical analysis and VS critically revised manuscript. All authors read and approved the final manuscript.
We thank mr. sc. dr. Zerina Jasarevic who translated the abstract to German language.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's Canada Institute for Scientific and Technical Information in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Glorious May in Montana~
Montana in May. What can be more spectacular than that? Come see the Mountains awaken in full-throated Spring. Streams running high and rushing to greet the rising rivers where fish are waiting to be caught. Wildlife is in abundance as they show off their young ones. Flowers are even more colorful as the days grow longer and warmer, which will mean you will have more time enjoying the glory that is Montana, Time AFTER Time!


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Trukfit Boys 3 Times Dope Turquoise T-Shirt
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Consumer Electronics Firms Upped Recycling 27% in 2012
Apple, Dell, HP and some 2,000 other consumer electronics companies increased the amount of electronics they recycled by about 27 percent last year, according to the Consumer Electronics Association.
The Second Annual Report of the eCycling Leadership Initiative says consumer electronics companies working in the eCycling Leadership Initiative recycled 585 million pounds of electronics in 2012, up from 460 million pounds in 2011. This represents a total increase of 95 percent since 2010 (300 million pounds). The report singles out Apple, Best Buy Dell, HP and Samsung as the top recyclers in 2012.
The eCycling Leadership Initiative is an industry effort spearheaded by CEA, designed to increase collaboration among consumer electronics manufacturers, retailers, collectors, recyclers, non-governmental organizations and governments.
The report also says by the end of 2012, 99 percent of the recycling handled by eCycling Leadership Initiative participants was conducted in third-party certified recycling facilities.
As of April 2013, there are more than 8,000 electronics recycling locations available to consumers nationwide.
The eCycling Leadership Initiative has set goals to increase the amount of electronics recycled responsibly to a billion pounds annually by 2016. The Billion Pound Challenge also aims to grow the number of eCycling collection sites available across the US.
Earlier this month, CEA and the Institute of Scrap Recycling Industries launched a crowdsourcing CRT Challenge to identify financially viable, environmentally conscious proposals for using recycled cathode ray tube (CRT) glass. As CRT technology has been displaced in the market by liquid crystal display (LCD), LED and plasma displays, the consumer electronics and recycling industries are working to find new ways to recycle old CRT glass.
US electronics recyclers have stockpiled 860 million pounds of cathode ray tube glass from TVs and monitors instead of recycling the material, according to a November 2012 report from Transparent Planet.
Some 72 percent of US consumers recycle electronics, up from 39 percent in 2010, according to Retrevo survey published earlier this week. Three years ago and in 2013, the most common reason cited was "not getting around to it," which the gadget review site calls "laziness." Those under 30 are the worst offenders with 17 percent saying they just don't get around to it compared to 8 percent of those over 30.
Last year, Best Buy, LG Electronics, Panasonic, Samsung, Sharp, Sprint and Staples joined the EPA's Sustainable Materials Management Electronics Challenge, committing to send 100 percent of the used electronics they collect to third-party certified refurbishers and recyclers, and to increase the amount of used electronics they collect.
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Dreamy damask with a polished sophistication that would look lovely in a variety of decor settings. Inspire your walls with the luxury of a Victorian silk fabric. With a noble nod to the finery of Victorian times, this wallpaper is pure luxury. A fresh spring silk, swirled with a resplendent damask print. This fine wallpaper brings Victorian inspired details to life for your walls with a delightful satin palette. This gorgeous damask wallpaper is printed with exceedingly fine silk emboss effects. This gorgeous damask wallpaper creates luxurious warmth in a room, enhanced to elegant heights with a fine silk texture. Romantic silk wallpaper, embossed with a resplendent damask motif.
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Telemedicine and Telesurgery in Cancer Care Conference
The Telemedicine and Telesurgery in Cancer Care Conference is chaired by Dr. Robert Satcher of the Department of Orthopedic Oncology. The conference is intended to explore the current issues and advances in using telemedicine as legitimate healthcare options and will feature several prominent experts in telemedicine including: Dr. Sergio Giralt, Dr. Curtis Lowery, Dr. Nina Antoniotti, Dr. Rob Williams, Dr. Ana Maria Lopez, and Dr. Andrew Evans. In the afternoon a series of invitation only breakout sessions will pose the question of what it will take to enable telemedicine efforts here at MD Anderson. These breakout sessions will include Legal, Government Policy, Clinical Networks, Clinical at MD Anderson, and Billing.
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Boom cackle and crack, your most awaited season is back. This year wont be a fuss, just sit tight, and well show you the entire rack. With great selections from blockbuster games and all you crave, Our Special Sales section will all soon be your fave. Indulge in some high quality Rubies costumes that will allow you to save!
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Hello! I'm an easy going professional with a real passion for life! Originally from Minnesota, I love to share my home with travelers and guests. While I have lost my upper midwest accent I always welcome guests with warm and genuine hospitality. In the summer months, I stay active by running, biking, camping and hiking. In the winter, I'm active with down hill skiing, snowshoeing and ice skating. I keep life simple yet meaningful by making a difference every day in my work and in the lives of others. I really enjoy big, bold red wines, strong coffee, grilled foods and ice cream! My style of hosting guests is personable, casual, respectful, informative and fun. I'm from a family of 11, yes I have 10 siblings - 6 brothers and 4 sisters. Some of my favorite travel destinations are the Pacific Northwest, Northern California, Australia, and the Upper Midwest. I tread lightly on the environment and surroundings, mindful of my carbon footprint.


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The deranged genius behind Tokyo Gore Police is back with a chilling new flick that's re-writing the hallowed history of the horror genre. Vampire Girl vs. Frankenstein Girl is the terrifying story of two classic monsters re-imagined as super hot – and extremely lethal – Japanese school girls. Gore rules supreme in this blood-cake cavalcade of carnage chosen as the winner of the Audience Award at the 2009 NY Asian Film Festival. Fan boys and movie blogs are already buzzing over this bloodbath du jour, and aficionados of psychedelic blood-filled chocolates, mad scientist principals, sumo wrestlers from hell, and sex-crazed school nurses are guaranteed to lose their heads over this old school splatter-fest.
There are moments in Vampire Girl vs. Frankenstein Girl when you might find yourself idly wondering what Bram Stoker and Mary Shelley would think of all this. There's not too much time to ponder such a head-spinning proposition, however, because of all the spraying blood, teen skin cutting, and steampunk artificial limbs on display. Director Yoshihiro Nishimura, of Tokyo Gore Police notoriety, unleashes this little offering as a full-out, looney-tune romp through some of the goriest tropes of the circa-2010 Japanese horror flick. Insofar as there is a plot, it concerns a cluelessly glib vampire girl (Yukie Kawamura) who has the hots for her classmate (Takumi Saito), a boy she tries to "turn" by giving him a chocolate truffle filled with her own blood. (Why didn't anybody in the Twilight series think of that?) But she'll have to get past a determined rival (Eri Otoguru), whose father just happens to be a mad-scientist type looking for a test subject for his theories of reanimation. Suggesting that this qualifies as plot is something of a stretch; this movie is so spasmodically bizarre, and so slavish in putting out its cartoon-violent set pieces, that it simply barrels along according to its own demented logic. In short, those who like this kind of thing will go for it--and anybody who feels that a movie might attempt to make some feeble kind of logic, whether emotional or tonal or spatial, will be bored pretty quickly by the relentless attempts at zaniness. Various Japanese teen fads are satirized, the most startling of which is a group of school girls who try to look black--a side plot that, even though it aims at poking fun at a teen craze, uses such outrageous racial imagery that it stands out for its offensiveness in a movie that hungrily seeks to offend. --Robert Horton
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This movie made me laugh uncontrollable at all the crazy, unbelievable stunts they pulled off! Yes, it can get gory, so if you have problems with this do not watch this movie. Read morePublished 3 months ago by Hasasuki
Best movie ever? Quite possibly. This is ridiculous to an extreme. It's more absurd than anything, but that absurdity translates into all sorts of things - romance and mutilation,... Read morePublished 4 months ago by R. Mutt
That was the most interesting and cool movie two different insane movies together which makes it when the best movies I've ever seenPublished 5 months ago by Kathy Verducci
Pretty much what I expected. It was great if your into this kind of thing.Published 8 months ago by leonxkennedy


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'high quality lens'
'poor low-light performance'
'simple, pocket-friendly point-and-shoot camera with a strong zoom'
'the Mode button lets you scroll swiftly left and right through shooting modes and, with a simple tap down, you can breeze through the scene modes'
'Bad menus and battery.'
'the increased sensitivity that the camera uses to get a good exposure may introduce more graininess than you really want.'
'sluggish when starting up.'
'Outdoor visibility was pretty
'there were still many times when the interface had us lost, confused, and frustrated.'
'The NV11 completely forgoes conventional controls and instead uses Samsung's Smart Touch interface'
'Occasional autofocus hunting.'
'I found only one truly irritating feature with the GX-10's design: The latches for the battery and SD Card media doors are small, fold-out twist locks.'
'Custom white balance is quite easy to set'
'premium features'
'In fact, it can be quite frustrating to use, especially for manually focusing.'
'unique "Smart Touch" interface'
'Since it is an ultra-compact, it's not exactly "easy" to hold,'
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£8.99 ex VAT
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This x16 PCI Express Riser Card lets you install a full-sized PCI Express card in a 1U or 2U server case, eliminating the expense of purchasing small form factor PCIe cards.
StarTech.com PCI Express Riser Card x16 Left Slot Adapter 1U/2U Servers - Riser card - for P/N: PCI1PEX1
We have a simple 'by weight' delivery charge for all orders, regardless of the number of items on the order. Each 20kg (or part thereof) is charged at £9.99 + VAT. Details of delivery cost for your order is clearly shown in the basket online and will be advised to you by the business adviser in store or over the phone.
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News Archive for 00/04/29
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AAPL Stock: 112.12 ( + 2.62 )
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Ben Mackin has updated his Liquid theme for Mac OS 8 and later. The new version fixes several bugs and adds in support for the disabled window widgets. His theme creation tutorial has also been updated.
Previously only available for Windows systems, Adobe next week is expected to officially introduce ActiveShare 1.0 for the Mac. The Java-based client, prematurely available on its ftp servers, allows users to edit, organize, and share photos over the Web. (ActiveShare.com was launched in October of last year with Windows-client support and has since been enhanced with integrated online photo printing services, which is not yet available for the Mac.)
The Apple Store's Special Deals area is offering a new Power Mac G4 450/128/20/Zip with a 17" Studio Display for $2848, which represents a savings of roughly $150 versus buying the two products separately from The Apple Store. Several retailers, however, are offering the 17" Studio Display on its own for $350, compared with The Apple Store's $500 price tag. The promotion runs from April 29 to July 1, or while supplies last.
An Apple TIL discusses master/slave IDE drive support in Power Mac G3/G4s. (Note that some later beige G3 models also support master/slave configurations, despite indications otherwise in the Apple TIL.)
Black Cat Systems has released MultiMode 3.3.5, a program for amateur radio operators and radio hobbyists that allows the transmission and reception of morse code, slow scan TV, and other modes. Version 3.3.5 adds the ability to transmit amateur radio packet transmissions.
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Looking for SLR-like image quality in a compact body? The EOS M offers the best of both worlds, with the added benefit of interchangeable lenses. However, its sluggish autofocus may deter point-and-shoot upgraders.
Pricing not available
The camera, which shipped elsewhere in April, lands in the US this October.
The Canon EOS M3 shoots 24.2 megapixel photos with a resolution of 6000x4000.
Canon's third-generation mirrorless model has an improved ergonomic design and features that promise faster overall shooting performance.
The third generation of Canon's mirrorless camera will be heading to a lot more countries this time around, but once again appears to be skipping the US.
The Canon EOS M3 offers dSLR-quality photos and a nice design, but its feature set is average, performance is sluggish and its price relatively high, at least in the US and the UK.
Faster autofocus and Wi-Fi networking help make Canon's high-end compact camera more competitive. So far it's only announced in China and Japan, though.
Canon has announced a new lens for its first interchangeable lens camera, as well as a new firmware update that promises faster AF speeds from the EOS M.
While it provides one of the best touch-screen experiences in its class and the compact body is quite comfortable to shoot with, the Canon EOS M's disappointing performance and blah feature set make it less attractive than competitors.


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Samsung Series 5 Ultrabooks pictures and hands-on
Officially speaking, the Samsung Series 9 laptop is not an Ultrabook - at least, Samsung has chosen not to call it one much like Apple hasn't bothered including the MacBook Air either. Instead, Samsung announced a couple of lesser machines at CES 2012, so Pocket-lint went hands-on to see if they're still impressive enough.
The kindest way to describe the Samsung Series 5 is by not comparing it to the Series 9. The Series 5 should not, ever, under any circumstances go double dating with the Series 9. It makes it look plump, dowdy and touch dull. It would sit ignored in the corner while all eyes were reserved for the other laptop.
Like we say, it's rather unfair because the Samsung Series 5 is something you'd otherwise feel proud carrying around on your arm. There are two models to choose from. There's the 13.3-inch version with integrated graphics or the 14-inch model with a dedicated GPU and an optical drive to enjoy as well. The price you pay for the latter is really in the body mass department which takes it up from 1.38kg to 1.84kg and that's pretty heavy for an Ultrabook. One has to wonder whether the disk drive is really worth it in this day and age?
Each has 8GB of RAM to play with and 300nit screens which are certainly perfectly good. Naturally, there are also Intel Core i5 processors at the helm and the choice of SSDs up to 16GB in size with the ExpressCache system to ensure fast starting and launching of apps, as we've seen on previous Samsung notebooks.
Neither laptop is wildly thin, despite the 14.9mm measurement at their thinnest, but they do have decent looking isolated keyboards and standard two-button trackpads which are easy enough to use, if slightly underwhelming.
So, unfortunately, despite trying to avoid it, the only way to sum up the Samsung Series 5 is by saying that they're perfectly good but they're just not as exciting as the Series 9. You'd also have to look at what Acer and Lenovo offer in the Ultrabook space as well.
No word on prices just yet, but we'll update when we know. Placed at £800 or less and they could really kick up a storm. Cost any more and they might just get lost in the crowd.
Apple's 21.5-inch iMac with a 4K display might finally launch next week
Microsoft Surface Book vs Surface Pro 4: What's the difference?
Microsoft Surface Pro 4 vs Surface Pro 3: What's the difference?
Microsoft Surface Pro 4 official: Price, release date, everything you need to know
- Microsoft Surface Book vs Surface Pro 4: What's the difference?
- Microsoft Surface Book: Everything you need to know about the world's fastest laptop
- Apple's 21.5-inch iMac with a 4K display might finally launch next week
- HP might debut a Star Wars-themed Windows 10 device this week
- Apple OS X El Capitan now out: Here's how to get the free update and more
- Apple OS X El Capitan almost ready for download: 10 new features to try
- Office 2016 for Windows 10 now available: How to get it and key new features explained
- Don't miss your chance to win a MacBook Air!
- Lenovo IdeaPad Miix 700: Better than the Microsoft Surface Pro?
- Apple patents fuel cell laptop battery for long-lasting MacBook
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- When is Android 6.0 Marshmallow coming to my phone?
- Microsoft Lumia 950 and Lumia 950 XL confirmed: What's the story?
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Hal Jordan, Earth's most popular Green Lantern, has been stripped of his powers, but it is up to him to fight the clones of the villain Sinestro, set loose by actions in the trilogy's first volume. In order to save the Earth, he may have to sacrifice himself by taking the Sinestro power rings on a one-way trip to the anti-matter universe.
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There seems to be a fear among Pirates fans that they are going to let the Nationals pass them. Sure the Nationals are hot, but that's a pretty monumental task.
@flyguy4_9 @shamtown If Bucs went 4-7 rest of the way which they likely won't Nats would have to be 11-0 to tie them that also won't happen
— Marty (@marty_leap53) September 18, 2013
I seriously doubt either of those two things happen. I don't drink. Ever. But some of you guys could really use a beer.
Also. Could you guys please make sure tonight's game is a sellout so you don't hurt A.J. Burnett's feewings.
Lots of empty seats. Lots!
— AJ Burnett (@wudeydo34) September 18, 2013
Hopefully Charlie Morton brings his "A" game. Today.
That's not something he's done in his last two starts.
There is reason to be optimistic. Morton hasn't been bad this year. Maybe those two starts are just a hiccup. Look at the bright side. He didn't hit a batter in either of those games, something he did do in the prior four games.
What makes me quake is that the Padres have enough lefties to make it really tough on Morton.
That's what Morton is going to do to the Padres today.
Morton has been Sterling against the Padres in two career starts.
I'm not sure who is more stunning. Ground Chuck or Mr. Archer.
So yeah, hopefully Chaz has his compete mode button pushed fully in.
His opponent, hailing from the bastion of Liberal, pinko, communism, Berkeley, California is Tyson Ross.
I'm so tired of these damn Padres trying to ruin the Pirates season. What is their problem?
Remember a few years back Root Sports focused on that dude just tearing into some Padres fan in San Diego? That was during the doldrums. Someone should find out who he is an get him on a plane for a playoff game.
Ross wasn't anything special the first time he faced the Buccos this year. Not even a quality start.
Mr. Ross has struggled on the road, though it's the only place he's won.
In addition his numbers have been steadily getting worse since his high water mark as a starter in July.
I don't know about you, but I hope this guy gets crushed today.
The outing against the Pirates I mentioned above was his only outing against them. He's never pitched at PNC Park.
First Pitch: 7:05 PM EST
Where To Watch: Root Sports, MLB.TV, FSSD


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We also sell new and used LPs and CDs both in store and online
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With 1.7 million freelancers, we'll match you with the perfect talent.
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We're a web hosting company and having several SaaS. Currently we're building another SaaS that need to be released at the end of this year, 75% of this application already implemented.
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You are a fan of decided fatboyz ? Come to discover the best forums decided fatboyz on the internet and share your experience with a community fan of decided fatboyz . You can also build a forum decided fatboyz and create your online discussion.
Hello! This is the forums I decided to quickly whip up for the community. I made it nice & free. Quite quickly as well.
community, hello!, this, forums, #decided, quickly, whip, made, nice, free, quite, well
Because pretending to be kids and trolls while lynching each other wasn't enough, we decided to broaden our horizons.
/co/'s, em's, because, pretending, kids, trolls, while, lynching, each, other, wasn't, enough, #decided, broaden, horizons
Welcome! If you are an RR player, than register to the Resistance Retribution Forums! Since there is no message board on RR, I decided to make this. . . for the players! Please register! Registration is free!
Seeing as the original TwilightSucks site (that I used to visit daily) got taken down off the Internet for some reason or other, I decided to make my own! XD
twilight, sucks, seeing, original, twilightsucks, site, (that, used, visit, daily), taken, down, internet, some, reason, other, #decided, make, own!
the year is 2200 and science and magic have become indistinguishable from each other. With this in mind, the magical world has decided to reveal itself.
magic, science, year, 2200, have, become, from, each, other, with, this, mind, magical, world, #decided, reveal, itself
Members of an old RP site that wanted the site to be fixed but never saw it fixed, untill a lone member decided to fix it by abandoning the site and making a new one
forbidden, eternal, asylum, realm, members, site, that, wanted, fixed, never, untill, lone, member, #decided, abandoning, making
Free forum : Since Crazy (old clan leader) has ordered MD8 to change it's name, we've decided to rename the clan to DW!DECIMATING WARRIORS!!! URAHHH!!!
free, decimating, warriors, since, crazy, (old, clan, leader), ordered, change, it's, name, we've, #decided, rename, dw!decimating, warriors!!!, urahhh!!!
Welcome to Mount Olympus, just recently the gods have decided to train some of their children up here, and you are one of them.
mount, olympus, welcome, just, recently, gods, have, #decided, train, some, their, children, here, them
Decided to run the game as a play-by-post for convenience.
nailstone, #decided, game, play-by-post, convenience
Free forum : Hey!!, teh new forum for our Guild, i decided to make one after Dark said he sucked at it, well Enjoy =p
Latu de Gama: Graphics ShopWelcome to the graphics group, Latu de Gama's graphics shop! We are consisted of many great people around friendcodes. We are the base of the art community! So I've decided to make this to show all the talent along the si
latu, gama, graphics, shopwelcome, group, gama's, shop!, consisted, many, great, people, around, friendcodes, base, community!, i've, #decided


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Jimmy Cliff to Perform on DirecTV's GUITAR CENTER SESSIONS, 1/25
|Related Links
|Trevor Hall Set for Two-Night Run at the Fox Theatre, 9/24-25
August 12, 2015
|DIRECTV's Guitar Center Sessions Season 10 to Feature Nick Jonas, Jason Mraz & More
May 20, 2015
|FIRST LISTEN: New Single 'Fire' from THE VOICE Winner Tessanne Chin
May 05, 2015
|Natural Vibrations to Play Fox Theatre, 6/6
May 01, 2015
An all new episode of GUITAR CENTER SESSIONS featuring the legendary Reggae star Jimmy Cliff will air, Friday, Jan 25th, at 9pm on DIRECTV's Audience Network (channel 239).
Check out Jimmy Cliff performing "Children's Bread" for his upcoming episode of Guitar Center Sessions HERE.
The season will continue with episodes featuring such dynamic artists as Mexican rock band Kinky, Prince protogee Andy Allo, and Skylar Grey of Dr. Dre's "I Need a Doctor" fame. Check out the remaining airdates below:
* Jan 25 Jimmy Cliff
* Feb 8 Kinky
* Feb 22 Andy Allo
* March 8 Skylar Grey
Already halfway into the season, there have been many showstopping moments. Below are just a few of those highlights (all approved for posting).
Ben Folds Five performing "Brick" - http://www.youtube.com/watch?v=utwSrZqiwcE
Joe Walsh performing "Funk #49" - http://www.youtube.com/watch?v=JbmtW31oAj8
Papa Roach performing "Leader of the Broken Hearts" - http://www.youtube.com/watch?feature=player_embedded&v=fps-isPSKL8
Meiko performing "Stuck on You" - http://www.youtube.com/watch?v=zPTamLDHaJo
Hoobastank performing "Running Away" - http://www.youtube.com/watch?feature=player_embedded&v=p5gAVb5xQMg
About Guitar Center Sessions
Guitar Center Sessions airs Fridays at 9pm in 2D hi-definition on DIRECTV's The Audience Network (channel 239)
Guitar Center Sessions is an award-winning live performance and interview music television series hosted by Nic Harcourt. Created, developed and produced by Guitar Center and airs exclusively on DirecTV. The series aims to provide artists, emerging and established, with a highly credible platform to expose their music and riveting back stories to a large audience. By developing high quality original music programming that focuses on conversations and themes pertinent to the artist's craft and creative process, Guitar Center continues to further its commitment to helping artists be heard in an ever changing, uncertain music business.
Official "At: Guitar Center" Website: http://gc.guitarcenter.com/sessions
Facebook: http://www.facebook.com/GuitarCenter
Youtube: http://www.youtube.com/user/GuitarCenterTV
About Author
- T.I., Fetty Wap & More Set for 2015 BET HIP HOP AWARDS
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- Leonel Garcia, Natalia Lafourcade Lead 16th Annual Latin GRAMMY Awards Nominations; Full List
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- IMAX And Better Life Sign Two-Theatre Sales Deal In China
- Stage and Screen Dancer and Choregrapher Daniel Levans Dies at 62
- Andrea Bocelli: Cinema Featuring Great Songs from the Silver Screen Set for THIRTEEN's Great Performances
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- William Shatner to Host STAR TREK 50th Anniversary Celebration at Inaugural Silicon Valley Comic Con
- JEFF DUNHAM: UNHINGED IN HOLLYWOOD Coming to Blu-ray/DVD, 11/17
- VIDEO: First Look - Emilio Estefan Releases Tribute Video 'We're All Mexican'
- Comedian Brian Regan Announces Spring 2016 Tour Dates
- Hearst Television to Premiere MATTER OF FACT WITH FERNANDO ESPUELAS
- VIDEO: Heineken Reveals SPECTRE TV Ad Starring Daniel Craig as James Bond; Watch It Now!
- The Aflac Duck Hits the Gym in New Television Commercial
- Public Enemy's 'Make You Blind' Featured on THE CHURCH HOUSE Documentary Soundtrack


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Publisher's Description+
The History browser allows you to browse through your entire history of LiveJournal entries, and view them in Xjournal. There are also quick-link buttons to open them in your browser for viewing or editing.
Xjournal has a built-in tool for creating LiveJournal polls.
The Glossary palette allows you to store text snippets for quick drag and drop access. It reads text files found in ~/Library/Application Support/Xjournal/Glossary and /Library/Application Support/Xjournal/Glossary.
Similarly to the Glossary, there is a palette containing your Safari bookmarks for quick access.
You can edit your friends and friend groups in Xjournal.
Xjournal will notify you when your friends have posted new entries.
What's new in this version:
- Made Post and Close the only posting behaviour, but it's now called "Post"
- Added a new preference under General to determine what happens when you post a locally-saved post with unsaved changes. Defaults to "Ask".
- "Small Userpic" bug is fixed
- Removed the "http://www..com" auto-fill from the Link sheet, as it was stupid
- The Browser in History now opens the calendar pages when you double-click a day, month, or year
- The browser also doesn't lose ... See all new features »