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PeerBlock 1.1 User Reviews
A newer version of PeerBlock is available.Or, Learn More About PeerBlock
out of 31 user reviews
"Great product"
Version: PeerBlock 1.1
blocks questionable sites
user lists
overly aggressive sometimes
"Good, Helpful Program"
Version: PeerBlock 1.1
Blocks unwanted trackers...Keeps tracing to a minimum, but it's not the be all end all to blocking your IP address. It will keep you 100x safer than using nothing, but it's not a proxy server
blocks some websites when there's no need to
Obviously some can't read the download information and just keep clicking on next...adware? Simply pay attention when you're installing and you won't have a problem opting out of their sponsors
"Does it's job, no adware"
Version: PeerBlock 1.1
Blocks what it's made to block. Adware is optional during the installation, so make sure you read before clicking accept. They should call it "moronware" instead of adware.
You're still on the internet, so you're never 100% protected.
Good low-maintenance IP blocker with no real downfalls.
"Decent execution, just stupid adware."
Version: PeerBlock 1.1
It appears to do it's job. blocking unwanted trackers. it's pretty spooky, I found some anti p2p organizations lurking on me which is really uncool but luckily it blocked them. to all the people [i saw at least one person saying comcast still "nailed" them, I'm pretty sure that has little to do with trackers and more to do with the fact it's really hard to eliminate the fact that the internet company unless you're using a vpn is going to know what you're looking at. if you're that concerned switch providers.
adware. it installed like 3 programs that weren't viruses i'm pretty sure, just stupid adware which i DID NOT agree to and it took me a little bit to remove them.
all in all i mean it's a good thing to have if you torrent things, or just like being private.
"does what needed"
Version: PeerBlock 1.1
no noticeble speed drop
adding to whitelist is a little annoying
"Awesome protection when used for what it was made for"
Version: PeerBlock 1.1
Blocks the stinking government spies, "over the top" anti-pirating/ anti-p2p spies, advertising spamming computers and a whole lot more. There are multiple 'lists' that you can add to the standard lists that come with the program. Peerblock updates the 'lists' every day or when you choose. If you are unable to access a site, Peerblock will flash in the taskbar and you can manually choose to allow http for the time values given or add the site as an exception, or simply elect to allow http, in which case, the icon will turn from blue to yellow to inform you that the program is effectively not running and blocking known bad addresses. Works perfectly when used appropriately, such as for torrenting.
None that I can think of as far as it's job goes. Maybe it could have a dirty great big sign on it saying, "NOT A FULL ON FIREWALL,USE FOR ENHANCED SECURITY ONLY", just for all those complete and utter idiots and losers out there who have no clue as to what the software they are downloading is actually used for. Then, instead of giving perfectly good programs such as peerblock a really bad rap for doing what it's supposed to do, they can just shut their cake holes and spend some time learning what programs such as Peerblock actually do.
If you are into torrents, don't hesitate to use this awesome tool. It's not the be all and end all of privacy programs, if you want to surf or torrent annonomously the use a proxy server, but at least it's another level of protection that can help keep those spying fools away from our front door.
"Installs Spyware"
Version: PeerBlock 1.1
False sense of security
This worthless program bundles with spyware, including programs named Coupon Companion and IB Updater. However, the biggest offender is "Incredibar." It adds a worthless toolbar to IE and Firefox and refuses to uninstall. I googled Incredibar to learn that it's spyware that hijacks your browsers to its advertising. I had chosen "custom install" to make sure to get Peer Block and Peer Block, but instead got this junk forced down my throat. I tried a Windows 7 rollback to a restore point, but that failed to get rid of this crap. Doesn't C-Net check the software here anymore?
Don't even remotely consider installing this spyware/junkware/crapware. If you do, you'll be sorry.
Reply to this review Read replies (2)
"False sense of security!"
Version: PeerBlock 1.1
Only blocks 1/3 of the IP addresses out there at best!
Blocks DHT and UDP addresses, which are necessary for downloading. See BitTorrent "Help" section. I was caught twice using PeerBlock. The program itself has not been upgraded in almost 3 years because the owner has been "lazy," his words, not mine.
Worthless protection! Don't bother. Get a pizza instead.
Reply to this review Read reply (1)
"Great IP Blocker!"
Version: PeerBlock 1.1
Works great, and has already blocked several IPs.
Blocked "oversee.net", which I had no idea was lurking on my PC from a past installation I had tried from CNET.
The program is also blocking over 1,000,000 IP addresses so far.
I have read these reviews and replies, and I hate to see so called "intelligent" people treat other people as if they are idiots just because they don't know that much about this program.
The program is great
"Many many thanx to the makers."
Version: PeerBlock 1.1
Blocks many many a-holes.
Many many morons who thinks this is a firewall.
I didn't know there were so many spyware companies/anti-p2p/botnets/campus police trying to block me from happiness untill I got this fine software.
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Former Colorado quarterback Joel Klatt is one of Fox Sports 1's rising stars in college football broadcasting. Besides being a regular on "Fox College Saturday," 9 a.m. Saturdays and contributing to "Fox Football Daily," he also broadcasts Thursday night games. He said he is looking forward to calling the OU at Baylor game on Nov. 9 for FS1.
Big 12 football: Fox Sports 1's Joel Klatt calls Oklahoma State one of the most overrated teams in the country
What's your assessment of the Big 12 race?
"Well, I think Oklahoma has put itself in the position where they're a clear leader. Someone is going to have to go and knock them off. I think they've won nine straight conference games going back to last year's Kansas State loss. They've got all these conference championships in their locker, if you will. (Bob) Stoops just knows how to get it done. With the biggest win for any team in the conference thus far in the season, which was last week at Notre Dame, I would put them as the clear favorite.
"Behind them I probably would go with Baylor and then at that point it's kind of a TCU, Texas Tech, Oklahoma State crap shoot. But Oklahoma State, last week I had them as one of my most overrated teams in the country, and then they went out and proved me right losing to West Virginia. They don't look like Oklahoma State should look. Their quarterbacks aren't throwing the ball with great efficiency. I don't know if (offensive coordinator Mike) Yurcich is really fitting in all that great. When you only score 21 points against Mississippi State and then you only score 21 points against West Virginia, there's a problem offensively. West Virginia was the worst defense in the country last year. Oklahoma State is just finding itself. It's trying to keep its head above water. Losing to West Virginia doesn't help in the league race."
Should the Cowboys consider going back to Clint Chelf at quarterback?
"I don't think anything is off the table. When your offense is sputtering, I think all things have to be analyzed. At this point with the body of work that Oklahoma State has presented to us, you would have to say that all positions are open. I don't want to say that they are panicking, but a lot of that is because of preseason hype. If you were just going to rank teams starting now based on what they have done this season, I don't think they would be in the top 25."
Continue reading this story on the...

subset: commoncrawl


text:
Malaria Active Epidemiology and Treatment Study
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
An observational cohort and malaria treatment study in Cambodia.
Drug: Dihydroartemisinin piperaquine
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|An Active Malaria Epidemiology Cohort Study With Evaluation of a 2 Day Versus 3 Day Treatment Regimen of DHA-Piperaquine for Patients With Uncomplicated Malaria
- Comparative efficacy. [ Time Frame: 4-5 months ] [ Designated as safety issue: No ]Comparative rates of malaria recurrence between the 2 and 3 day DP regimens at 42 days after treatment of malaria infection, diagnosed by positive PCR-corrected malaria microscopy.
|Study Start Date:
|September 2010
|Study Completion Date:
|December 2012
|Primary Completion Date:
|February 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: 3 day therapy
Total dose split over 3 days (3 tablets per day)
Drug: Dihydroartemisinin piperaquine
40/320 mg tablets, 9 tablets total
Other Name: Artekin, Duo-cotexcin
Experimental: 2 day therapy
Total dose split over 2 days (4.5 tablets per day)
Drug: Dihydroartemisinin piperaquine
40/320 mg tablets, 9 tablets total
Other Name: Artekin, Duo-cotexcin
Detailed Description:
This is an active observational Cohort Study of malaria epidemiology with a nested two arm, randomized, open label Treatment Study comparing the efficacy, safety, tolerability and pharmacokinetics of a two versus three day course of Dihydroartemisinin-Piperaquine (DP) for those developing uncomplicated malaria. At the conclusion of the Cohort Study, a subset of volunteers with documented exposure to Plasmodium vivax during the study will be treated with primaquine as presumptive anti-relapse therapy directed against the exoerythrocytic malaria stages of P. vivax, and followed passively for an additional 6 months.
|Ages Eligible for Study:
|18 Years to 65 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Otherwise healthy volunteer, 18-65 years of age, eligible for care at an RCAF facility, and at risk for contracting malaria
- Able to provide informed consent
- Likely to reside in endemic area for the duration of the study
- Available for follow-up for anticipated study duration, and agrees to participate for the duration of the study
- Authorized by local commander to participate in the study if on active duty
Exclusion Criteria:
- History of allergic reaction or contraindication to DHA or piperaquine
- Significant acute comorbidity requiring urgent medical intervention
- Pregnant or lactating female, or a female of childbearing age who does not agree to use a highly effective method of birth control during the study
- Clinically significant abnormal EKG, including a QTc interval > 500 ms.
- Judged by the investigator to be otherwise unsuitable for study participation
Please refer to this study by its ClinicalTrials.gov identifier: NCT01280162
|Oddar Meancheay
|Oddar Meancheay, Cambodia
|Principal Investigator:
|David Saunders, MD, MPH
Additional Information:
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Armed Forces Research Institute of Medical Sciences, Thailand
|ClinicalTrials.gov Identifier:
|NCT01280162 History of Changes
|Other Study ID Numbers:
|WRAIR # 1737, HRPO Log Number A-16251
|Study First Received:
|January 19, 2011
|Last Updated:
|October 18, 2014
|Health Authority:
|Cambodia: Ministry of Health
Cambodia: National Ethical Committee for Health Research
Keywords provided by Armed Forces Research Institute of Medical Sciences, Thailand:
Plasmodium falciparum, Plasmodium vivax
Additional relevant MeSH terms:
Parasitic Diseases
Protozoan Infections
Anti-Infective Agents
Antiparasitic Agents
Antiprotozoal Agents
Pharmacologic Actions
Therapeutic Uses
ClinicalTrials.gov processed this record on October 09, 2015


text:
An investigative report released last week helped to shed some light on an issue that is plaguing America's veterans.
A new IRS rule prohibits large employers from canceling their plans and dumping their employees onto the ObamaCare exchanges.
The May 28 release of a scathing Veterans Administration Office of Inspector General (OIG) report on dishonest scheduling practices at the VA clinics in the Phoenix, Arizona, area has produced calls for — and reports of — investigations for criminal prosecution of the rogue officials who wrote the fraudulent reports.
The president's brain mapping initiative will soon get underway with the implantation of chips in the brains of veterans.
While Americans are already experiencing a rise in their health insurance premiums because of ObamaCare, it seems taxpayers may also see an increase in their taxes as a result of the costliness of Medicaid — also attributable to the new healthcare law.
Sen. Richard Burr (R-N.C.) picked the eve of the Memorial Day weekend to incur the wrath of veterans organizations with an "Open letter to America's Veterans."
The emerging cover-up of long waiting periods for care at Veterans Administration hospitals has burgeoned into national news in recent weeks, with "secret waiting lists" being exposed in half a dozen or more locations and President Obama calling for an inspector-general inquiry into the matter.
A Christian, pro-family group in England is warning of the dire consequences of a decision by the U.K. government to move ahead with a controversial plan that would allow for the creation of "three parent" babies through in vitro fertilization.
Federal Judge Mark W. Bennett (of the United States District Court for the Northern District of Iowa) issued an order on May 21 that halts enforcement of the Obama administration's HHS mandate against two Christian colleges — Dordt College in Iowa and Cornerstone University in Michigan.
JBS CEO Art Thompson's weekly news video update for May 26 - June 1, 2014.


text:
- Infowars - http://www.infowars.com -
Inside Job? Iraqi govt 'involved in deadly bombings to get US troops to stay'
Posted By aaron On August 26, 2010 @ 3:04 pm In Iraq,Old Infowars Posts Style | Comments Disabled
Russia Today
Thursday, August 26, 2010
More than 40 people have been killed in a string of bombings that have rocked Iraq. In Baghdad alone, over 20 bombs exploded in at least 12 separate incidents. Today's bombings are raising questions the Iraqi government's ability to deal with an ongoing insurgency. Sabah Al-Mukhtar from the Arab Lawyers Association says the bombings may actually be the Iraqi government's way to get US troops to stay.
Having A Supply Of Healthy Foods That Last Just Makes Sense
Article printed from Infowars: http://www.infowars.com
URL to article: http://www.infowars.com/inside-job-iraqi-govt-%e2%80%98involved-in-deadly-bombings-to-get-us-troops-to-stay%e2%80%99/
Click here to print.
Copyright © 2015 Infowars. All rights reserved.


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What do you do if you're not happy with the limited Windows/OS X range that makes up mainstream computing today? If you'd like to run your PC on something different, you can always try Linux. For those who really want to strike out on their own and try something new, though, there are a number of choices. Chrome OS While Google's Chrome OS is a modified version of Linux, its take on it is so different that it qualifies as all-new. Chrome OS runs exactly one program -- the Chrome browser. Whatever you want to do on your Chrome OS computer, you need to do it through the browser window. While the focus on browser-based operation makes Chrome OS unsuitable as a general-purpose computer, it can do most of … Continue reading
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On News 88.9 KNPR
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Main Number: 1-702-258-9895
Toll Free: 1-888-258-9895
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Coming up on Thursday's program...
Are we alone in the Universe? It is a question that has plagued humanity for centuries. We'll look at why humans continue to search for extra-terrestrial intelligence.
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When Maggie meets Tom. When attraction meets logic…when lust trumps sanity…all bets are off.
His arms held her in a vice like grip as his words slid into the space between them. "Play along with me. I've had a rough morning."
"It's about to get a whole lot rougher," Maggie hissed as she stepped on his instep.
"Ohhhhh! That's my favorite sister for ya." The handsome stranger laughed and slid into a deckchair and plunked her down on his lap. His lips brushed her earlobe in a move that felt suspiciously like a kiss. A tingle rippled through her body like an ice cream soda's fizz on a hot day.
"Try that again and I'll put you over my lap and spank you," he said, his lips hot against her cheek.
Maggie smothered the starburst sensation his lips had sparked, and glared at him. "Take your best shot, buster, but I wouldn't give a girl like me such easy access to your family jewels. Know what I mean?"
She glanced down in the general direction of his crotch. "You try spanking me, and I'll have you singing soprano."
"Don't make promises you can't keep." He whispered close to her ear – his words punctuated with a look that would make a nun strip.
God, he was gorgeous! And the creep knew it! "Are you willing to take the chance?"
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|Product #: EMC2753005_TQ
Common and Proper Nouns (with Capitalization) (Resource Book Only) eBookGrade 3
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This unit demonstrates that common nouns are words that name any person, place, or thing and do not begin with a capital letter. Proper nouns name specific people, places, or things and begin with a capital (city/Portland). Students underline, circle, or write words according to directions.
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Trade deadline passes without any late moves
Seattle • Real Salt Lake's front office has had varying success with September additions.
Two years ago, the team signed Yordany Alvarez, who has become a solid backup for captain Kyle Beckerman. A year ago, the team brought in attacker David Viana, who was waived earlier this season after never really breaking into the first team.
This season, with Salt Lake sitting in first place, general manager Garth Lagerwey is standing pat. Major League Soccer's roster freeze deadline came and passed Friday afternoon without a September addition for RSL.
"We're pretty comfortable," coach Jason Kreis said. "We certainly [were] listening and not closing our ears. But we feel pretty confident" in the team's makeup.
Former Bolton Wanderer Ricardo Gardner had been on trial with the team for several weeks, but has since left Utah.
Big timed
The Seattle Sounders can pack CenturyLink field, but there were plenty more eyeballs watching the top two teams in the league battle Friday night. The match was one of just three national TV appearances for RSL this year.
"It is what it is now," said defender Chris Wingert. "This has been happening for years. I think everybody around the league respects us. But I don't really know what the reason is why we don't get a lot of national television games. But there's nothing we can do about it."
Flying the flag
The red, white and blue were well represented on the Seattle turf.
Nick Rimando and Kyle Beckerman were on opposite benches from Clint Dempsey and Eddie Johnson after all four celebrated together earlier this week in Columbus, Ohio, as the U.S. downed Mexico and qualified for the 2014 World Cup. The future of U.S. soccer was also on display, as RSL's Luis Gil and Seattle defender DeAndre Yedlin, teammates on the U.S. Under 20 team, did battle.
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May 20, 2014
8:30-11:30 am
SC1: Animal Models of Pain: Progress and Challenges - (DETAILED AGENDA)
Jeffrey S. Mogil, Ph.D., E.P. Taylor Professor of Pain Studies, McGill University
Many are frustrated with the lack of translational progress in the pain field, in which huge gains in basic science knowledge obtained using animal models have not led to the development of many novel and clinically effective compounds. A careful reexamination of animal models of pain is therefore warranted. This course will describe the current implementation of animal models of pain, discuss a wide range of modulatory factors affecting data obtained within them, lay out the case for the replacement of current models by more sophisticated ones, and describe progress toward that goal.
Topics to be Covered:
2:00-5:00 pm
SC3: Nanotechnology for Enhancing Bioavailability of Poorly Soluble Drugs - (Detailed Agenda)
Shaukat Ali, Ph.D., Technical Support Manager, BASF Corp.
Wantanee Phuapradit, Ph.D., Executive Vice President, Research & Development, Kashiv Pharma
Lipa Shah, Ph.D., Principal Scientist, Chemical and Pharmaceutical Profiling, Novartis Institutes for BioMedical Research, Inc.
Michael Perlman, Ph.D., Senior Scientist II, Biopharmaceutics and Physicochemical Profiling, Takeda Pharmaceuticals
Salin Gupta Patel, Associate Principal Scientist, Nanoparticles Technology Development Team Lead, Merck Research Labs
A significant number of new chemical entities (NCEs) are practically insoluble and thus, the industry is struggling to find solutions by adapting the non-conventional innovative and cost effective technologies in development of these molecules. This workshop will be aimed at understanding the significance of nanotechnology in formulation development and its role leading to enhance solubility and bioavailability of drug candidates.
6:00-9:00 pm (Dinner)
Jeffrey E. Green, M.D., Chief, Transgenic Oncogenesis and Genomics Section, Laboratory of Cancer Biology and Genetics, National Cancer Institute
Zoë Weaver Ohler, PH.D., Principal Scientist, Preclinical Evaluation Team Leader, Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research (NCI)
Neal Goodwin, Ph.D., Vice President Corporate Research Development, Champions Oncology, Inc.
Bruce R. Zetter, Ph.D., Charles Nowiszewski Professor of Cancer Biology, Department of Surgery, Harvard Medical School
Metastasis is the primary cause of patient mortality from cancer. This course will present methods that are used to study metastases in vivo using genetically-engineered mouse (GEM) models, standard xenografts, and patient derived xenografts to elucidate mechanisms controlling metastatic spread and therapeutic strategies using these preclinical models. Techniques used to disseminate tumors at metastatic sites and assess metastatic growth in vivo will be discussed, including tail vein and intracardiac injection, ex vivo pulmonary metastasis assay, luciferase imaging, and other non-invasive imaging modalities. Examples of specific topics to be covered include:
• Approaches to studying metastases in mice
• Strategies for experimental design with metastatic models
• Metastatic breast cancer models
• Metastatic ovarian cancer models (GEM and orthotopic)
• Melanoma metastatic models (orthotopic)
• PDX metastatic models
May 22, 2014
6:30-9:30 pm (Dinner)
Arvind Rao, Ph.D., Assistant Professor, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center
Geoffrey A. Bartholomeusz, Ph.D., Assistant Professor and Director of the siRNA Core Facility, Department of Experimental Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center
Lesley Mathews Griner, Ph.D., Research Scientist, Biomolecular Screening and Profiling/Probe Development Group, National Center for Advancing Translational Sciences, NIH
Pierre Alexandre-Vidi, Ph.D., Post-doctoral Fellow, Department of Basic Medical Sciences, Purdue University
The course will provide an overview of the various 3D cell culture models available, their strengths and weaknesses, and where and how these models are being used, specifically for oncology research. The instructors will share their experiences on how they tested and evaluated various cell culture reagents and growth matrices, what worked and what didn't and what you need to consider when setting up low and high throughput screening experiments using 3D cell cultures in your lab. The challenges working with 3D cell cultures, from experimental design to data analysis will be discussed.
*Separate registration required
Keynote & Exhibit Pass
Event At A Glance
Final Brochure
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The exhibit hall has sold out the past four years, so please contact us early to reserve your place. To customize your sponsorship or exhibit package for 2015, contact:
Joseph Vacca
Associate Director, Business Development
June 10-11
Preclinical Models in Oncology
Imaging in Oncology
Targeting GPCRs
Predicting Drug Toxicity
Blood Brain Barrier
Mastering Medicinal Chemistry
Chemical Biology for Target Validation
June 11-12
Tumor Models for Immunotherapy
3D Cellular Models
Targeting Histone Acetylation
Functional Genomics Technologies
Property-Based Drug Design
Chemical Proteomics for Target Validation
June 9 - Short Courses
Allosteric Modulators of GPCRs, (PAMs NAMs)
Imaging of Blood-Brain Barrier Function
Drug Metabolism and Its Impact on Decisions in Drug Discovery & Development
Understanding and Dealing with Drug Disposition in CNS
Navigating the CiPA Landscape
June 11 - Short Courses
How to Best Utilize Organotypic 3D Cell Cultures in Oncology
3D Printing
PDX Models Update
Training Seminar
Applying Pharmacology to New Drug Discovery


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Richard White: Who is responsible for repairs for a water shutoff valve?
Q. In our condominium building, each unit has a water shutoff valve. Does the condominium have any responsibility for maintenance of the plumbing or damage that occurs from leaks or repairs beyond the shutoff valve?— J.H.
New Port RicheyA. This is a document requirement, most times found in the declaration. I have found that most condominium documents say that when a utility line serves only one unit, the owner of the unit would be responsible for the repairs and maintenance. If the line serves two or more units, then the condominium would be responsible. From your description and if the documents have this requirement, then the shutoff value appears to be that point that divides the responsibility. Now as to responsibility for the damage from a water spill or leak, that is a different set of requirements. Damage to personal property including unit damage is normally a unit owner's responsibility regardless of how or where the water entered the unit. That would cover any penetration of water including rain, wind blown rain, an upstairs pipe that breaks, hot water heaters failure, floods from main common area water lines, or any other source of water. In fact, it is a legal requirement that each condominium owner obtains and carries property insurance for losses in their unit. Here is how most claims for water damage are handled. Each unit owner would be responsible for the repairs to their unit's personal property. There is one exception and that is the condominium may be responsible to replace unfinished drywall. The best source to find the requirements for your condominium is to ask your insurance agent and your attorney.
Q. At a recent annual meeting of our condominium, we elected a past president to the board. After the election, several facts were disclosed about his past actions. The first is that he is a Canadian citizen and only lives here for a few weeks each year. He also have violated our rules by building a patio on common grounds at his unit as well as opening a wall and installing a window without approval by the board. For the election, he assisted some unit owners in filling out their ballots. And this is some of the violations that he has done. One of his campaign promises was to keep the fees the same this year. In lieu of all the violations and improper actions that this man has done, is there anything that we can do about our situation with this person being on the board?— F.E.
ClearwaterA. Here is a quote from the VFW Magazine: "The Supreme Court stated that the First Amendment's free speech protection applies even to lies." The ruling was made to determine if politicians could be held accountable for their campaign promises or any speech given. In your situation, if the members elected the director, good or bad, the members are to be blamed, not the candidate. It is the members' duty to know the details of the person they vote for or to verify the facts. Requirements of the person must be verified by each individual before they vote. Citizenship and residency are not a requirement to serve on a condominium board unless your documents say otherwise. The filling out of a ballot as you described only means that those ballots should be voided. That is not a criminal offense that would involve jail time. If the members were too thoughtless to evaluate each candidate, then they only have themselves to blame. If he is that bad, the other directors can strip him of all officers' duties. He does not need to be president as the directors have the final vote to elect officers.
Q. In our condominium, the stairwells have deteriorated to a point they need to be removed and repaired. They are a hazard and could involve a liability lawsuit if someone falls or trips. Does the board have the power to contract for the repairs and special assess the members? Is it a board decision or do the members need to vote on the repairs and special assessments?— M.A.
SeminoleA. This is straight out of the statutes (FS 718.111 and other sections). The board of directors has the responsibility to operate and maintain the common areas. To do so, they have the duty and right to budget or special assess to raise the necessary money to pay for repairs. The owners have no say-so to disallow such repairs. Yes, if someone is injured because of a fall on your steps needing repairs, they could receive a large award in court. That is one reason that property inspections should be made frequently to discover common areas that need repairs. At the next board meeting, the reports should be discussed and scheduled repairs should be introduced. This is one of the key responsibilities of the board of directors.
Q. Our HOA board has a monthly workshop prior to the monthly owner's meeting. Much is accomplished at these meeting Owners can attend but cannot talk at the meeting but can address their problems or ask questions at the end of the meeting. This system works well but we would like your opinion on the subject. We are told that the board cannot make motions and vote at the workshop. We were told that Florida law requires that all voting must take place at the owner's meeting. Is this true?— M.S.
Vero BeachA. This week I received several question on workshop meetings. Your question, along with all the other questions, indicates that boards do not understand the statute requirements and proper board functions. The HOA Act Section FS 720.303 and the Condominium Act Cection FS 718. 112 say anytime a meeting of directors, where a majority of directors are present and association business is discussed, the meeting is considered to be a board meeting. An agenda and proper notice is posted and the members allowed three minutes to discuss agenda items. That in so many words says that the statutes do not allow workshops. As for the "monthly owner's meeting," I think you mean board meeting. Your directors must read the statutes and determine the proper meeting protocol. Meeting in a workshop is simply illegal. It really indicates that your directors need to start asking questions from professionals that manage and operate associations and legal guidance. One of the best sources of information is the Community Association Institute (CAI). The Web page is www.caionline.org. There are several CAI chapters in Florida. You can search a chapter in your area at www.flcaj.com.
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text:
|Publication number
|Publication type
|Application number
|Publication date
|Sep 16, 2004
|Filing date
|Mar 30, 2004
|Priority date
|May 31, 2001
|Also published as
|Publication number
|Stephen Pacetti
|Original Assignee
|Pacetti Stephen D.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (8), Referenced by (13), Classifications (18)
|External Links: USPTO, USPTO Assignment, Espacenet
[0001] This is a Continuation of U.S. Ser. No. 09/872,816, filed on May 31, 2001, allowed.
[0002] 1. Field of the Invention
[0003] This invention relates to an apparatus and method for coating implantable devices such as stents.
[0004] 2. Description of the Background
[0005] Stents act as scaffoldings, functioning to physically hold open and, if desired, to expand the wall of the passageway. Typically, stents are capable of being compressed, so that they can be inserted through small cavities via catheters, and then expanded to a larger diameter once they are at the desired location. Mechanical intervention via stents has reduced the rate of restenosis; restenosis, however, is still a significant clinical problem. Accordingly, stents have been modified to perform not only as a mechanical scaffolding, but also to provide biological therapy.
[0006] Biological therapy can be achieved by medicating the stents. Medicated stents provide for the local administration of a therapeutic substance at the diseased site. In order to provide an efficacious concentration to the treated site, systemic administration of such medication often produces adverse or toxic side effects for the patient. Local delivery is a preferred method of treatment in that smaller total levels of medication are administered in comparison to systemic dosages, but are concentrated at a specific site. Local delivery thus produces fewer side effects and achieves more favorable results.
[0007] A common method of medicating a stent is by depositing a polymeric coating, impregnated with the therapeutic substance, on the surface of the stent. A polymer dissolved in a solvent is applied to the stent. A therapeutic substance can be dissolved or dispersed in the composition. The solvent is allowed to evaporate to form the coating. The application of the composition can be performed by spraying the composition on the stent or immersing the stent in the composition.
[0008] The solvents employed with the composition can be categorized as having a high vapor pressure or low vapor pressure. Non-volatile solvents evaporate very slowly from the composition causing coating defects such as inconsistency in the coating thickness and formation of "cob webs" or "pool webs" between the stent struts. A solution to this problem is to coat the stent at elevated temperatures to increase the evaporation rate of the solvent. However, not all drugs are stable at elevated temperatures. Volatile solvents have the tendency to evaporate very quickly from the composition resulting in a coating which has a powdered consistency and adheres poorly to the surface of the stent. Accordingly, what is needed is an apparatus and process for coating stents that does not suffer from the aforementioned drawbacks.
[0009] In accordance with one aspect of the invention, a method of forming a coating for an implantable medical device, such as a stent, is provided. The method comprises applying a composition to the stent in an environment having a pressure other than ambient pressure. For compositions including a non-volatile solvent, the pressure can be less that 760 torr; for compositions including a volatile solvent, the pressure can be greater than 760 torr. The composition can include a polymer, such as an ethylene vinyl alcohol copolymer dissolved in a solvent, such as dimethylacetamide. Optionally, a therapeutic substance can be added to the composition, such as actinomycin D, paclitaxel, docetaxel, or rapamycin. In accordance to one embodiment, the composition can be applied by spraying the composition on the stent. During the act of applying, the stent can be rotated and/or moved in a linear direction along the longitudinal axis of the stent. The stent can beta radially expandable stent, such as a balloon expandable or self-expandable type.
[0010] In accordance with another aspect of the invention, a method of forming a coating for a stent is provided, comprising positioning a stent in a chamber; applying a fluid to the stent; and adjusting the pressure of the chamber to increase or decrease the evaporation rate of the fluid.
[0011] In accordance with another aspect of the invention, an apparatus for coating implantable medical devices such as stents is provided. The apparatus includes a chamber for housing a stent and a pressure controller for adjusting the pressure of the chamber during the coating process to a pressure below or above 760 torr. In one embodiment, an applicator can be provided for spraying a composition at the stent. A support assembly holds the stents in the chamber and can be connected to a motor for providing rotational and/or translational motion to the stent. A temperature controller can also be provided for adjusting the temperature of the chamber.
[0012]FIG. 1 illustrates a pressure chamber for forming a coating on a stent.
[0013] Referring to FIG. 1, there is illustrated a pressure chamber 10 defining a workspace 12 for depositing a composition on a stent 14 for forming a coating. A chamber opening (number omitted) can be provided for allowing a user to gain access into workspace 12. A hatch 16 can be placed over the chamber opening for tightly sealing the opening during the deposition process. The size of workspace 12 needs to be large enough so as to enclose a support assembly 18, such as a mandrel, for adequately supporting stent 14 during the coating process. Workspace 12 can be large enough so as to support any suitable number of support assemblies 18 and stents 14.
[0014] In one embodiment, support assembly 18 can be connected to a first motor assembly 20A for rotation of support assembly 18 along the central, longitudinal axis x of stent 14. A second motor assembly 20B can be additionally provided for translational movement of support assembly 18 in a linear direction, back and forth, along a railing 22. The rotational and translational motion of stent 14 during the application of the composition can result in a more uniform deposition of the coating.
[0015] An applicator 24, such as a spray valve, penetrates through the wall of pressure chamber 10 and is positioned in the vicinity of stent 14. Commercial applicators are available from Spray Systems Co., EFD International Inc., and Badger Air-Brush Co., one specific model of which is the EFD 780S spray device with VALVEMATE 7040 control system. To avoid spray rate alterations due to the pressure difference, applicator 24 can be placed entirely within pressure chamber 10. The nose of applicator 24 can be positioned at any suitable distance away from stent 14, for example at about 1 cm to about 10 cm. An operator should be capable of adjusting the distance depending on the particular circumstances of the deposition process. Applicator 24 is capable of applying the composition at a pressure of, for example, about 10 torr to about 1000 torr. In accordance with an alternative embodiment, support element 18 can be in a vertical position and applicator 24 spraying in a horizontal direction.
[0016] A pressure controller such as a pump 26 is in fluid communication with workspace 12 so as to create pressures below or above 760 torr (1 atm) in pressure chamber 10. In one embodiment, a cold trap 28 can be provided for preventing the solvent or condensation from penetrating into pump 26 should pump 26 be used to create a vacuum in pressure chamber 10. A filter 30, such as a mist filter, can also be provided to prevent droplets of coating composition from possibly reaching and damaging pump 26. Other components of pressure chamber 10 can include a throttle valve 32 for opening and closing the communication line to pump 26, a baratron vacuum gauge 34 for measuring the pressure in workspace 12 independent of the type and composition of the solvent vapor, and an absorbent 36 for capturing the bulk of the composition over-spray. Gas, such as air, can be pumped or bled into pressure chamber 10 for creating a convection flow inside pressure chamber 10, to actively scavenge the solvent vapor from workspace 12 and out through pump 26 so as to prevent solvent vapor build-up. A diffuser 38 can be used to diffuse or "spread out" the flow of gas so as to minimize disturbance of the spraying process. A bleed valve 40 can be used for adjusting the flow rate of gas through diffuser 38. In addition to rapidly removing the solvent vapor from pressure chamber 10, bleed valve 40 can also be used to control the chamber pressure by working in concert with throttle valve 32.
[0017] Pressure chamber 10 can also be connected to a heating and/or cooling source 44 so as to control the temperature of workspace 12. A cooler deposition environment, such as temperatures of less than 50� C. may be preferred depending on the chemical stability of the therapeutic substance and the type solvent used. In lieu of providing an external heating source, an internal component, such as heating and/or cooling coils, can be provided.
[0018] To form a coating on a surface of stent 14, the surface of stent 14 should be clean and free from contaminants that may be introduced during manufacturing. However, the surface of stent 14 requires no particular surface treatment to retain the applied coating. Stent 14 is mounted on mandrel 18 and the composition is sprayed via applicator 24 at a pressure of, for example between 10 to 1000 torr. During the spraying of the composition, stent can be rotated at about 1 to about 120 rotations per minute. Stent 14 can also be moved in a linear direction at speed of about 1 to about 20 cm/sec. The temperature of chamber 10 should be maintained at a temperature that does not adversely affect the therapeutic substance or the coating process—for example at about 20� C. to about 50� C.
[0019] For a solvent having a low vapor pressure (e.g., below 30 torr at the temperature of application), or in other words non-volatile substances, the solvent evaporates very slowly from the composition, leading to irregularities in the coating thickness and "cob webs" or "pool webs" between the stent struts. Accordingly, compositions have been applied in short bursts, interrupted by the drying of the composition between each application step to minimize coating defects. Reducing the pressure of chamber 10 below ambient pressure during the coating process allows the solvent to evaporate more rapidly. Rapid evaporation of the solvent allows the composition to be applied continuously for depositing a coating of a suitable thickness or weight while minimizing coating defects such as "pool webs." The pressure employed in pressure camber 10 depends on the type of solvent employed. Table 1 is an exemplary list of non-volatile solvents and the suitable range of pressure which can be used in the process of the present invention:
TABLE 1 Exemplary Pressure Ranges Solvent torr @ 20� C. Dimethylsulfoxide 0.8-<760 Dimethlacetamide 0.9-<760 Dimethylformamide 5.4-<760
[0020] For a solvent having a high vapor pressure (e.g., above 30 torr at the temperature of application), or in other words volatile solvents, the solvent evaporates extremely rapidly from the composition, leading to difficulties in the application of the composition to the stent. Application of such compositions often lead to coatings having powdered consistency and poor adhesion of the coating to the surface of the stent. Increasing the pressure in pressure chamber 10 above ambient pressure causes the solvent to evaporate more slowly leading to a coating with a smoother surface, more uniform composition, and better adhesion. Table 2 is an exemplary list of volatile solvents and the suitable range of pressure which can be used in the process of the present invention:
TABLE 2 Exemplary Pressure Ranges Solvent torr @ 20� C. Toluene >760-2000 n-propanol >760-3400 Acetone >760-9000
[0021] The embodiments of the composition can be prepared by conventional methods wherein all components are combined, then blended. More particularly, in accordance to one embodiment, a predetermined amount of a polymer or combination of polymers can be added to a predetermined amount of a solvent or a combination of solvents. If necessary, heating, stirring and/or mixing can be employed to effect dissolution of the polymer(s) into the solvent(s)—for example in an 80� C. water bath for two hours. A therapeutic substance can be also added to the composition. The therapeutic substance should be in true solution or saturated in the blended composition. If the therapeutic substance is not completely soluble in the composition, operations including mixing, stirring, and/or agitation can be employed to effect homogeneity of the residues. The therapeutic substance may be added so that dispersion is in fine particles. The mixing of the therapeutic substance can be conducted at ambient pressure and at room temperature.
[0022] The polymer or combination of polymers chosen must be biocompatible and minimize irritation to the vessel wall when the device is implanted. The polymer may be either a biostable or a bioabsorbable polymer. Bioabsorbable polymers that could be used include poly(hydroxyvalerate), poly(L-lactic acid), polycaprolactone, poly(lactide-co-glycolide), poly(hydroxybutyrate), poly(hydroxybutyrate-co-valerate), polydioxanone, polyorthoester, polyanhydride, poly(glycolic acid), poly(D,L-lactic acid), poly(glycolic acid-co-trimethylene carbonate), polyphosphoester, polyphosphoester urethane, poly(amino acids), cyanoacrylates, poly(trimethylene carbonate), poly(iminocarbonate), copoly(ether-esters) (e.g. PEO/PLA), polyalkylene oxalates, polyphosphazenes and biomolecules such as fibrin, fibrinogen, cellulose, starch, collagen and hyaluronic acid. Also, biostable polymers with a relatively low chronic tissue response such as polyurethanes, silicones, and polyesters could be used. Other polymers include polyolefins, polyisobutylene and ethylene-alphaolefin copolymers; acrylic polymers and copolymers; vinyl halide polymers and copolymers, such as polyvinyl chloride; polyvinyl ethers, such as polyvinyl methyl ether; polyvinylidene halides, such as polyvinylidene fluoride and polyvinylidene chloride; polyacrylonitrile; polyvinyl ketones; polyvinyl aromatics, such as polystyrene; polyvinyl esters, such as polyvinyl acetate; copolymers of vinyl monomers with each other and olefins, such as ethylene-methyl methacrylate copolymers, acrylonitrile-styrene copolymers, ABS resins, and ethylene-vinyl acetate copolymers; polyamides, such as Nylon 66 and polycaprolactam; alkyd resins; polycarbonates; polyoxymethylenes; polyimides; polyethers; epoxy resins; polyurethanes; rayon; rayon-triacetate; cellulose, cellulose acetate; cellulose butyrate; cellulose acetate butyrate; cellophane; cellulose nitrate; cellulose propionate; cellulose ethers; and carboxymethyl cellulose. Ethylene vinyl alcohol is functionally a very suitable choice of polymer. The copolymer possesses good adhesive qualities to the surface of a stent, particularly stainless steel surfaces, and has illustrated the ability to expand with a stent without any significant detachment of the copolymer from the surface of the stent. The copolymer, moreover, allows for good control capabilities over the release rate of the therapeutic substance.
[0023] Representative examples of solvents include chloroform, acetone, water (buffered saline), dimethylsulfoxide (DMSO), propylene glycol methyl ether (PM,) isopropyl alcohol (IPA), n-propyl alcohol, methanol, ethanol, tetrahydrofuran (THF), dimethylformamide (DMF), dimethyl acetamide (DMAC), benzene, toluene, xylene, hexane, cyclohexane, heptane, octane, nonane, decane, decalin, ethyl acetate, butyl acetate, isobutyl acetate, isopropyl acetate, butanol, diacetone alcohol, benzyl alcohol, acetone, 2-butanone, cyclohexanone, dioxane, methylene chloride, carbon tetrachloride, tetrachloroethylene, tetrachloroethane, chlorobenzene, 1,1,1-trichloroethane, formamide, and combination thereof. The solvent should be capable of placing the selected polymer into dissolution at the selected concentration and should not adversely react with the therapeutic substance.
[0024] The therapeutic substance can include any agent capable of exerting a therapeutic or prophylactic effect in the practice of the present invention such as inhibition of migration and/or proliferation of smooth muscle cells. The agent can also be for enhancing wound healing in a vascular site and improving the structural and elastic properties of the vascular site. Examples of agents include antiproliferative substances as well as antineoplastic, antiinflammatory, antiplatelet, anticoagulant, antifibrin, antithrombin, antimitotic, antibiotic, antioxidant, and combinations thereof. One suitable example of an antiproliferative substance includes actinomycin D—synonyms of which include dactinomycin, actinomycin IV, actinomycin I1, actinomycin X1, and actinomycin C1. Examples of suitable antineoplastics include paclitaxel and docetaxel. Examples of suitable antiplatelets, anticoagulants, antifibrins, and antithrombins include sodium heparin, low molecular weight heparin, hirudin, argatroban, forskolin, vapiprost, prostacyclin and prostacyclin analogs, dextran, D-phe-pro-arg-chloromethylketone (synthetic antithrombin), dipyridamole, glycoprotein IIb/IIa platelet membrane receptor antagonist, recombinant hirudin, thrombin inhibitor (available from Biogen), and 7E-3B� (an antiplatelet drug from Centocore). Examples of suitable antimitotic agents include methotrexate, azathioprine, vincristine, vinblastine, fluorouracil, adriamycin, and mutamycin. Examples of suitable cytostatic or antiproliferative agents include angiopeptin (a somatostatin analog from Ibsen), angiotensin converting enzyme inhibitors such as CAPTOPRIL (available from Squibb), CILAZAPRIL (available from Hoffman-LaRoche), or LISINOPRIL (available from Merck); calcium channel blockers (such as Nifedipine), colchicine, fibroblast growth factor (FGF) antagonists, fish oil (omega 3-fatty acid), histamine antagonist, LOVASTATIN (an inhibitor of HMG-CoA reductase, a cholesterol lowering drug from Merck), monoclonal antibodies (such as PDGF receptors), nitroprusside, phosphodiesterase inhibitors, prostaglandin inhibitor (available form Glazo), Seramin (a PDGF antagonist), serotonin blockers, steroids, thioprotease inhibitors, triazolopyrimidine (a PDGF antagonist), and nitric oxide. Other therapeutic substances or agents which may be appropriate include alpha-interferon, genetically engineered epithelial cells, rapamycin, and dexamethasone.
[0025] The dosage or concentration of the active agent required to produce a favorable therapeutic effect should be less than the level at which the active agent produces toxic effects and greater than the level at which non-therapeutic results are obtained. The dosage or concentration of the active agent required to inhibit the desired cellular activity of the vascular region can depend upon factors such as the particular circumstances of the patient; the nature of the trauma; the nature of the therapy desired; the time over which the ingredient administered resides at the vascular site; and if other therapeutic agents are employed, the nature and type of the substance or combination of substances. Therapeutic effective dosages can be determined empirically, for example by infusing vessels from suitable animal model systems and using immunohistochemical, fluorescent or electron microscopy methods to detect the agent and its effects, or by conducting suitable in vitro studies. Standard pharmacological test procedures to determine dosages are understood by one of ordinary skill in the art.
[0026] Stent is broadly intended to include self-expandable stents, balloon-expandable stents, and stent-grafts. One of ordinary skill in the art, however, understands that other medical devices on which a polymer can be coated can be used with the practice of the present invention, such as grafts (e.g., aortic grafts), endocardial leads, valves, and the like. The underlying structure of the device can be virtually any design. Stents are typically defined by a tubular body having a plurality of bands or cylindrical elements interconnected by connecting elements. The device can be made of a metallic material or an alloy such as, but not limited to, cobalt chromium alloy (ELGILOY), stainless steel (316L), "MP35N," "MP20N," ELASTINITE (Nitinol), tantalum, nickel-titanium alloy, platinum-iridium alloy, gold, magnesium, or combinations thereof. "MP35N" and "MP20N" are trade names for alloys of cobalt, nickel, chromium and molybdenum available from standard Press Steel Co., Jenkintown, Pa. "MP35N" consists of 35% cobalt, 35% nickel, 20% chromium, and 10% molybdenum. "MP20N" consists of 50% cobalt, 20% nickel, 20% chromium, and 10% molybdenum. Devices made from bioabsorbable or biostable polymers could also be used with the blended composition.
[0027] While particular embodiments of the present invention have been shown and described, it will be obvious to those skilled in the art that changes and modifications can be made without departing from the embodiments this invention in its broader aspects and, therefore, the appended claims are to encompass within their scope all such changes and modifications as fall within the true spirit and scope of the embodiments this invention.
[0028] This is a continuation of U.S. Ser. No. 09/872,816, the entire disclosure of which is incorporated by reference.
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|Feb 4, 2014
|Abbott Cardiovascular Systems Inc.
|Implantable device having a slow dissolving polymer
|Jul 13, 2007
|Apr 1, 2014
|Abbott Cardiovascular Systems Inc.
|Tailored aliphatic polyesters for stent coatings
|May 14, 2009
|Apr 15, 2014
|Abbott Cardiovascular Systems Inc.
|Polymers comprising amorphous terpolymers and semicrystalline blocks
|May 14, 2009
|Apr 15, 2014
|Abbott Cardiovascular Systems Inc.
|Coating comprising a terpolymer comprising caprolactone and glycolide
|Jan 10, 2014
|Nov 18, 2014
|Abbott Cardiovascular Systems Inc.
|Implantable device having a coating with a triblock copolymer
|Apr 18, 2008
|Dec 23, 2014
|Abbott Cardiovascular Systems Inc.
|Block copolymer comprising at least one polyester block and a poly (ethylene glycol) block
|Aug 1, 2007
|Feb 10, 2015
|Abbott Cardiovascular Systems Inc.
|Dioxanone-based copolymers for implantable devices
|Nov 15, 2013
|Jul 28, 2015
|Abbott Cardiovascular Systems Inc.
|Biodegradable triblock copolymers for implantable devices
|Aug 28, 2003
|Dec 8, 2005
|Doron Shabat
|Self-immolative dendrimers releasing many active moieties upon a single activating event
|U.S. Classification
|International Classification
|Cooperative Classification
|European Classification


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At a press conference at the Harris County Democratic Party headquarters, Kim Ogg says her focus, if she becomes the next Harris County DA, will be to fight crime with 21st century tactics and to dismantle organized crime.
"The duty of the district attorney is not to simply convict, but to see that justice is done. And I intend to bring that idealism in all of our actions."
Ogg, a former felony prosecutor in the DA's office, says she will seek to re-prioritize the office's resources, including forfeiture funds.
"I think there's an over-criminalization right now, and a hyper-focus on individuals who are in possession of small amounts of drugs and other non-violent crimes, and I think it comes at the expense of a focus on crimes that really affect our quality of life and our economy."
Rice University Political Science professor Mark Jones says Ogg will be facing another seasoned professional in Republican Devon Anderson, a former prosecutor and judge, who was named by the governor to serve out the term of DA Mike Anderson, her late husband.
"In many ways, the race will come down to a broader Democratic vs Republican trend in the county, to the extent to which things turn blue, that's good for Ogg. On the other hand, if it retains its Republican bent as in say 2010, then that will be good news for Anderson."
While Ogg is the first candidate to formally announce, Anderson said she planned to lead the office for years to come. Voters will choose a new district attorney in November 2014.


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St. Matthew's House won't pursue homeless shelter at Bonita Springs site
St. Matthew's House isn't opening a homeless shelter at a proposed Bonita Springs site.
"Our plans to purchase and develop the property are off the table," said Vann Ellison, president and chief executive officer of St. Matthew's House.
"Because of issues related to the contract, the buyer and the seller couldn't reach terms and we are now out of a contract in the Bernwood property."
He declined to elaborate.Plans had called for the former Synovus Bank at the northwest corner of Old 41 Road and Cockleshell Court to be expanded from about 2,500 to 3,700 to become the St. Matthew's House administrative center. An additional stand-alone building would have been erected during a two-phase process. The charity had proposed 168 beds.
St. Matthew's House presently has no property in Lee County under contract.
"Obviously, we are very sad because of the very fact that we don't have the potential to expand in Lee County," Ellison said. "We are saddened that we cannot meet the needs of women and families."
Controversy in Bonita Springs arose this year when the owner of an empty bank building and more than 6 acres along Old 41 Road agreed to sell the site for more than $3 million to a private trust affiliated with St. Matthew's House for a shelter.
Bonita Springs City Council members unanimously approved a temporary moratorium on permits for future shelters that went into effect May 18, after the St. Matthew's House application already was on file.
St. Matthew's House officials have been searching for a couple of years for a site to build a homeless shelter in south Lee County.
Plans to build a shelter at two locations on Old 41 Road in Bonita Springs, including the former Causeway Lumber site, fell through.
"This is a loss for our community," said Janet Bartos, executive director of the Lee County Homeless Coalition. Bartos added that she had hoped it would be built by now.
Mayor Ben Nelson said every time the specific site issue arose, it has been a "horrible experience" of neighbors against neighbors. And, he said, each time the community is happy to get through it.
"Our goal is to continue to formulate and set up rules and regulations so that are citizens don't have to go through this trauma again and that way we don't have to ever go through this again," said Nelson.
He said regulations need to reflect the community's actual needs and desires.
Some residents, including Bonita Springs Charter School parents, raised concerns about opening a shelter near a school, and the possibility that it could lead to increased crime.
Ben Hershenson, a member of BSafe Bonita, a newly formed citizens group, said he feels "relieved."
Now, Hershenson said the city has time to put in place regulations and standards specific to homeless shelters that weren't in place.
"Our chief concern has always been for the safety and security of the children at Bonita Springs Charter School," Colleen Reynolds, charter school spokeswoman, said in an email.
"We wish St. Matthew's House the very best in the future to find a suitable site that works well with the surrounding neighborhood."
As of Wednesday, the developer for the Bernwood site was still is in the process of moving forward with its development order application to build a shelter there.
"We are proceeding forward status quo," said Charlie Maurer, developer for the Bernwood site and agent for the estate.
Maurer said they are waiting for a response from the city.
"This is obviously of great concern to all those involved in BSafe Bonita, as our opposition was and continues to be with any unregulated homeless shelter at this location," Jeanne Watson, a member of BSafe Bonita and a Cedar Creek resident for seven years, said in an email. "Therefore, we will continue to work with the city in any way we can to prevent this incompatible use from being approved at this location."
Councilman Peter Simmons, whose two children attend Bonita Springs Charter School that's less than a half-mile north of the site, said he saw a very strong and vocal grass-roots organization opposing the shelter in town. He said more than 90 percent of the hundreds of emails he has received from Bonita Springs residents were opposed to the shelter.
"All along, I have said the health, welfare and safety of the residents of Bonita Springs is a top priority of mine on this or any other issue," Simmons said.
Despite the latest deal being off, Ellison said the charity remains interested in expanding into southern Lee County or northern Collier County.
In 2011 Ellison about 35 percent of the people who seek help at St. Matthew's House in East Naples are from Bonita Springs and south Lee County. There has been a waiting list since June 2007.
"Homelessness is something that we can no longer ignore; each community must take responsibility and do its part to help," Bartos said.
Bartos said she hopes St. Matthew's House continues to look for opportunities in Bonita Springs.
Recently, a donor offered the charity a 2.9 acres property adjacent to the existing St. Matthew's House on Airport-Pulling Road in East Naples.
The charity cannot built a homeless shelter on the former DeVoe used car lot because of zoning constraints. Ellison said the charity knows it doesn't want to expand the soup kitchen, nor open a detox center.
"Right now, there are no plans on the property," he said. "We are going to evaluate and try to draw up preliminary plans."
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Jobseekers urged to visit 69 job fairs offering 150,000 jobs-A A +A
Wednesday, April 30, 2014
THE Department of Labor and Employment (Dole) on Wednesday urged jobseekers to visit any of the 69 venues of the Labor Day Job Fair across the country that will offer close to 150,000 local and overseas employment opportunities.
In a media forum, Labor Secretary Rosalinda Baldoz said they are hoping that those looking for jobs or better jobs will take advantage of the opportunities provided by job fairs on Thursday, May 1, for them to find jobs.
"The resiliency of our workers, against all odds, is beyond compare. This Labor Day, we aim to give back the service they deserve by fast-tracking the matching of jobseekers and employers, particularly in identified areas where skills are highly in demand or available through the conduct of Job Fairs," Baldoz said.
And to help the jobseekers achieve their goals, Baldoz has urged employers participating in these job fairs to improve their hiring rates, as a way of helping jobseekers, especially the fresh graduates, land their first jobs.
"We will be gratified if employers participating in our job fairs on Labor Day can improve their hiring rates and increase the number of applicants hired-on-the-spot (HOTS)," Baldoz said.
She noted how the annual average HOTS is about 15 percent, marked by last year's 16 percent after 20,905 out of 127,880 total of registered jobseekers got hired immediately.
The labor chief urged employers to be a little flexible in considering "near hires" or applicants that are "nearly fit" for a job, but may be lacking in one or two qualifications that can be compensated by an applicants' other strong points.
Among the jobs to be offered in the Jobs Fair are in the industries of cyber services, information technology, call centers, hotel and restaurant, tourism, health and wellness, wholesale and retail trade, construction, automotive, real estate, banking, finance, insurance, and cargo.
Baldoz, in the meantime, advised participants to the job fairs to brush up on relevant labor market information by looking for occupations that fit their qualifications and inclinations.
"This is one of the best ways you can match yourselves with productive opportunities or even be hired on the spot during job fairs," Baldoz advised.
For first-time job seekers, she advised them to accept the first job that comes their way and fits their qualifications.
"This is the way to earn experience and pick up job-ready skills," said the official.
Baldoz said jobseekers must also be ready with their resumes and other documentary requirements in order to hasten their applications.
The Job Fair will also feature pre-employment documentation services provided by the National Bureau of Investigation, Bureau of Internal Revenue, Professional Regulation Commission, Social Security System, Pag-Ibig, PhilHealth, Philippine Postal Corporation, and National Statistics Office.
In a related development, labor coalition group, Nagkaisa, said that 30,000 workers are set to hold their traditional Labor Day protests in Manila also on Thursday.
They said this is because the Aquino administration has again failed to address important issues raised by their representatives during the pre-Labor Day dialogue in Malacanang on Wednesday.
Nagkaisa claimed that Aquino has not changed in his four years as President as he continues to dishonor workers and their concerns.
"President Aquino continues to ignore for four years the issues, which we believe would help impact the plight of the working people. Workers are feeling deprived of the benefits due them despite of their great contribution to improving economy," the Nagkaisa said in a statement.
"It is not straight. It is not right. It is unjust if growth is shared only by a few," it further said.
Members of the numerous labor groups are set to march from Welcome Rotonda to Mendiola around 9 a.m. and will hold a program in Mendiola around 11 a.m. (HDT/Sunnex)
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25th Annual Spring Boat Show
Nearly all the area's major dealers will be on hand with hundreds of boats on display. The show will feature a wide variety of booth displays with all kinds of marine accessories, and services. Port Charlotte's "Fishin' Frank" and his crew of experienced and entertaining guides will conduct fishing seminars all four days of the show. Frank's new fishing simulator will give show visitors a chance to experience the excitement of fighting everything from bass to billfish. This is a great opportunity to see, compare and buy boats and accessories. Boat shows are so appealing to the public because you can shop without driving all over Southwest Florida. The Caloosa Café & Pub will be there, featuring great food and all kinds of drinks. And the Greyhound Track and Poker Room will be in full operation throughout the show. Show hours are 10 a.m. to 6 p.m. on Thursday – Saturday and 10 a.m. to 5 p.m. on Sunday. Admission is $8.00 (kids under 16 are free with paid adult admission). Parking is free.
Naples Fort Myers Greyhound Track
10601Bonita Beach Road SE, Bonita Springs, FL 34135


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text: Shorty and Esalene | IBDB: The official source for Broadway Information IBDB: The official source for Broadway Information Official Broadway League sites: - sites - broadway.org broadwayleague.com broadwayfanclub.com kidsnightonbroadway.com stagespecs.org tonyawards.com Quick Search For: In This Category: All Show People/Org. Theatre Season Shorty and Esalene Performer Productions ProductionsDate of ProductionsSingin' the Blues[Play, Drama, Play with music, Original] Performer: Shorty and Esalene [The Lindy Hoppers]Sep 16, 1931 - Oct 24, 1931 Find out where Shorty and Esalene and are credited together © 2001-2015, The Broadway League, All Rights Reserved. (Copyright and Disclaimer)


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- Northern New York Newspapers
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AKWESANE - Members of the St. Regis Mohawk Tribe will head to the polls to elect a new chief, sub-chief, and clerk for three-year terms.
The polls will be open from place 9 a.m. until 5 p.m. at the community building on state Route 37 in Akwesasne. All voters must be registered tribal members. Each voter must sign in and present their tribal enrollment card or valid photo identification prior to receiving their ballots for the election and must put their enrollment number next to their name, according to the tribal election ordinance.
Incumbent Chief ark Garrow is being challenged by Paul Thompson, Roger Thomas, Monica Jacobs and Gary Cole.
Sub-chief Stacy Skidders also has several challengers on the ballot. They include Eric Thompson, Pam Brown and Sharon Thompson.
Tribal Clerk Corleen Jackson-Jacco faces a challenge from Clarissa Terrance-Chatland and Cecil Garrow.
Thousands of readers like you have made Northern New York Newspapers the number one ranked website* for local news and sports coverage in the north country.
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WASHINGTON -- Eyes glaze over at the mere mention of entities such as the Pension Benefit Guaranty Corporation or the Governmental Accounting Standards Board. But the PBGC's sudden prominence is symptomatic of the increasingly troubled relationship between America's welfare state and American capitalism, or those portions of capitalism that are appendages of the welfare state. And the GASB is pertinent to the parallel crisis of state and municipal welfare states.
Last week a judge said that United Airlines, now in its third year of bankruptcy protection, can, as a step toward leaving bankruptcy, default on four pension programs covering about 120,000 current and former employees, programs currently $9.8 billion underfunded. The PBGC will guarantee payments of $6.6 billion, so promised benefits will be reduced by $3.2 billion.
This will improve United's competitive position by relieving it from making more than $3 billion in pension fund payments over the next five years. But what, then, of United's competitors?
When the PBGC took over responsibility for $3 billion of US Airways' promised benefits for current and retired employees, that put pressure on United to lighten its load. And now that the PBGC has lightened it, what is Delta, which has lost $6.3 billion in the last five quarters, to do? What about American, Continental, Northwest? The mere existence of the PBGC encourages a chain reaction. And outside the airline industry, many other corporations under stress are watching.
Under a progressive formula, the PBGC pays only portions of the pension obligations it inherits, but larger portions for lower-income retirees. It is funded, inadequately, by fees on corporations with the kind of pensions the PBGC guarantees. Its current obligations exceed its assets by $23.3 billion. Private-sector defined-benefit pension plans are underfunded by an estimated $450 billion. Who will bail out the PBGC? Taxpayers beware.
The judge, practicing industrial policy, said the deal reached through collaboration between United and the PBGC will help United attract financing to keep flying. But perhaps United -- or US Airways, or a carrier contemplating bankruptcy as a means of escaping ``legacy'' costs -- should go out of business. The airline industry is afflicted with excess capacity and is hemorrhaging red ink -- more than $30 billion since 2000 -- largely because of the older carriers' promises of medical care and pensions for current and retired employees.
Bernie Sanders and Robert Reich Are Confused by Economics. And Government. And Reality | Seton Motley
Here we go: Jeb Bush's campaign weighing whether to have George W. hit the trail for him in South Carolina | Allahpundit


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Egomania: Island without Hope
1986. Germany. Christoph Schlingensief. 84 min.
Thursday, May 29, 2014, 7:00 p.m.
Theater 3 (The Celeste Bartos Theater), mezzanine, The Lewis B. and Dorothy Cullman Education and Research Building
Egomania: Island without Hope
1986. Germany. Directed by Christoph Schlingensief. With Tilda Swinton, Udo Kier. Set on a remote and icy island in the Eastern Sea, Egomania is Schlingensief's only melodrama. When Baron Tante Teufel (Aunt Devil), the island's vampire-like sovereign, fears that the love story between a couple might unhinge the island's dull existence, he goes berserk. A torrent of desire, intrigue, and murder ensues. In German; English subtitles. 84 min.
In the Film exhibition Christoph Schlingensief
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text: The Canopy goggle is celebrated for its comfortable fit and large field of vision. Oakley's HDO (High Definition Optics) lenses are among the best for optical clarity and impact protection. Ample venting and an anti-fog coating ensure sound performance and comfort. Bonus: A percentage of the proceeds from sales of this goggle benefit Shane's family.


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Article ID: 826955 - View products that this article applies to.
On This Page
On August 11, 2003, Microsoft began investigating a worm that was reported by Microsoft Product Support Services (PSS), and the Microsoft PSS Security Team issued an alert to inform customers about the new worm. A worm is a type of computer virus that generally spreads without user action and that distributes complete copies (possibly modified) of itself across networks (such as the Internet). Generally known as "Blaster," this new worm exploits the vulnerability that was addressed by Microsoft Security Bulletin MS03-026 (823980) to spread itself over networks by using open Remote Procedure Call (RPC) ports on computers that are running any of the products that are listed at the beginning of this article.
This article contains information for network administrators and IT professionals about how to prevent and how to recover from an infection from the Blaster worm and its variants. The worm and its variants are also known as W32.Blaster.Worm, W32.Blaster.C.Worm, W32.Blaster.B.Worm, W32.Randex.E (Symantec), W32/Lovsan.worm (McAfee), WORM_MSBLAST.A (Trendmicro), and Win32.Posa.Worm (Computer Associates). For additional information about recovering from this worm, contact your antivirus software vendor. For additional information about antivirus software vendors, click the following article number to view the article in the Microsoft Knowledge Base:
49500If you are a home user, visit the following Microsoft Web site for steps to help you protect your computer and to recover if your computer has been infected with the Blaster worm:
(https://support.microsoft.com/kb/49500/ )List of Antivirus Software Vendors
http://windows.microsoft.com/en-US/windows/products/security-essentialsFor additional information about a worm that is similar to the Blaster worm and that exploits the vulnerabilities that were addressed by Microsoft Security Bulletins MS03-026 (823980) and MS03-007 (815021), click the following article number to view the article in the Microsoft Knowledge Base:
(https://support.microsoft.com/kb/826234/ )Virus Alert About the Nachi Worm
Symptoms of InfectionIf your computer is infected with this worm, you may not experience any symptoms, or you may experience any of the following symptoms:
Technical DetailsFor technical details about the changes that this worm makes to your computer, contact your antivirus software vendor.
To detect this virus, search for a file that is named Msblast.exe, Nstask32.exe, Penis32.exe, Teekids.exe, Winlogin.exe, Win32sockdrv.dll, or Yuetyutr.dll in the Windows\System32 folder, or download the latest antivirus software signature from your antivirus vendor, and then scan your computer.
To search for the these files:
PreventionTo prevent this virus from infecting your computer, follow these steps:
RecoveryBest practices for security suggest that you perform a complete "clean" installation on a previously compromised computer to remove any undiscovered exploits that can lead to a future compromise. For additional information, visit the following Cert Advisory Web site:
http://www.cert.org/tech_tips/win-UNIX-system_compromise.htmlHowever, many antivirus companies have written tools to remove the known exploit that is associated with this particular worm. To download the removal tool from your antivirus vendor, use the following procedures depending on your operating system
Recovery for Windows XP, Windows Server 2003, Standard Edition, and Windows Server 2003, Enterprise Edition
Recovery for Windows 2000 and Windows NT 4.0The Internet Connection Firewall feature is not available in Windows 2000 or Windows NT 4.0. If Microsoft Internet Security and Acceleration (ISA) Server 2000 or a third-party firewall is not available to block TCP ports 135, 139, 445 and 593, UDP ports 69 (TFTP), 135, 137, and 138, and TCP port 4444 for remote command shell, follow these steps to help block the affected ports for local area network (LAN) connections. Note that TCP/IP Filtering is not available for Dial-up connections. If you are using a Dial-up connection to connect to the Internet, you should enable a firewall.
For additional technical details about known variants of the Blaster worm, visit the following Symantec Web sites:
http://technet.microsoft.com/en-us/security/cc165596.aspxFor additional information about how to recover from this worm, contact your antivirus vendor.
Microsoft provides third-party contact information to help you find technical support. This contact information may change without notice. Microsoft does not guarantee the accuracy of this third-party contact information.
For the most current information from Microsoft about this worm, visit the Microsoft Virus Solution and Security Center
(http://go.microsoft.com/fwlink/?LinkId=242148)for resources and tools to keep your PC safe and healthy. If you are having issues with installing the update itself, visit Support for Microsoft Update
(http://go.microsoft.com/fwlink/?LinkId=242149)for resources and tools to keep your PC updated with the latest updates.
office. To obtain support for virus-related issues, visit the following Microsoft Virus Support Newsgroup Web site:
news://msnews.microsoft.com/microsoft.public.security.virusFor additional security-related information about Microsoft products, visit the following Microsoft Web site:
http://www.microsoft.com/protect/default.mspxFor additional security-related information about Microsoft Security Bulletins MS03-026 and MS03-039, visit the following Microsoft Web sites:
Article ID: 826955 - Last Review: March 2, 2012 - Revision: 17.0
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KCC culinary students compete for Mixed Plate scholarshipUPDATED 6:42 PM HST Mar 08, 2013
The rules are simple: come up with an entree and dessert using a pre-selected local product. This year, it's Ho Farms tomatoes. The winner of the competition will be announced this weekend at KCC's Hookipa benefit.
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Memphis St. Jude Dream Home Giveaway
And the winner is ...Congratulations to Michael Michie of Collierville, Tennessee — winner of the Memphis St. Jude Dream Home house.
View all prizes and winners.
for donating time and materials to build the beautiful St. Jude Dream Home Giveaway house.
Proceeds benefit St. Jude Children's Research Hospital in Memphis, Tennessee. Giveaway conducted by ALSAC/St. Jude Children's Research Hospital. Raffle licensed by the Tennessee Division of Charitable Solicitations and Gaming. View terms and conditions.


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Why reporters fear Team Obama
Many reporters covering national security and government policy in Washington these days are taking precautions to keep their sources from becoming casualties in the Obama administration's war on leaks. They...
or email email@example.com
Published: October 6, 2013 | 11:53pm
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