text:
Virtual worlds (VWs) are powerful three-dimensional technologies where users can assume identities and interact with others. While designed as open-platforms for creativity, expression, and experimentation by recreational users, VWs were once lauded for their potential applications to business. Today, much of the business community has either moved on from the hype of VWs or struggles to understand whether value can be obtained by using VWs. This paper attempts to provide an understanding of these outcomes through the analysis of assessments written by 59 business professionals, who each spent an extended period of time in a popular VW during the peak of the hype. From these assessments, four broad perspectives on the value of VWs to organizations (or lack thereof) were identified, along with challenges facing use of VWs if they are to become more widely used within business.
• A useful paper – good analysis of hype, why hype did not materialise in the VWs with regards to business opportunities/being a space for business activities
- Notes a prediction in 2007 that "80 percent of active Internet users would have a VW presence by the end of 2011 (Gartner Research, 2007)." (p2)
--> This might have been the key point - if there were loads of people in VWs, there would be business potential (see p11 also). Since there wasn't such an influx, there wasn't - hence the real question might be: 'Why weren't more people in VW?'
--> Surely, e.g. in gaming, there are many opportunities for advertising, but in a relatively limited market?
• Data derived from an exercise done by postgraduate students in business course who were asked to go into Second Life and develop opinions as to the usefulness for business. Only those with prior business experience were used
• Overall (p7) – 36.8% saw it as having some value, 41.4% no value, 14.3% contingent value, 7.5% future value
- Most value seen as advertising platform, enhance customer experience, training, meetings
- Main problems seen as need to learn the platform, inability to control the environment, technology no fast enough, wrong kind of users
--> This actually suggests the need for a limited form of virtual world, tailored for business users only. On the lines of LinkedIn or something.
• The argument revolves around affordances, and how the technologies are relevant in one context but not in another [i.e. relational] – thus SL is good for people who want freedom, gaming environment, but this is not useful for businesses
--> The environment of freedom etc. actually is not what businesses want… In fact, businesses thrive on limited social openness - i.e. they need to lock people into certain discourses, perceptions, etc which will lead them to directed purchase decisions [- this must relate to the markets approach somehow – Callon etc…. i.e. markets are about developing assemblages with particular dynamics…]
• Good point about hype (p11) – that for much research
- "the primary focus is on how business might use VWs, not if. This approach creates an unspoken assumption underlying prior work – creation of affordances naturally leads to business utilization. However, capabilities of a technology do not determine use (Wasko, et al., 2011). In fact, additional capabilities and functions afforded by virtual worlds have been found to be harder to utilize, even for experienced users, thus reducing willingness and expectations of use for business activities (Luse, Triplett, & Mennecke, forthcoming)." (p11; original emphasis).
--> Good point I think - i.e. hype-discourse assumes the potentials will be used, and thus develops a number of positive scenarios. By focusing on a couple of examples, e.g. IBM, this is taken as proof that they will be used, hence the positive assumption is taken as justified and then developed
Please note - these are rough notes only, based on a first reading. They may be useful to someone interested in an alternative perspective on this paper.
However, these notes do not necessarily represent a final opinion, and are subject to revision in the future.
However, these notes do not necessarily represent a final opinion, and are subject to revision in the future.


text:
|Accession Numbers: EG11398 (EcoCyc), b3510, ECK3494
Synonyms: yhiB, yhhC
Subunit composition of
HdeA dimer, inactive form of acid-resistance protein = [HdeA]2
acid-resistance protein, possible chaperone = HdeA
HdeA is a periplasmic protein that plays a role in resistance to low pH [Gajiwala00, Masuda03].
HdeA is not required for growth on rich or minimal media [Link97a]. The effects of insertion mutations on cell growth are observed to vary depending on the construction of the mutant allele [Link97a]. A hdeA mutant had severely reduced survival after four hours of growth in fresh or spent LB at pH 2.5 [Mates07].
The crystal structure has been solved at 2.0 Å resolution [Gajiwala00]. A crystal structure is presented [Yang98b]. HdeA dimers dissociate at low pH and the monomer is involved in protecting proteins from acid-induced denaturation and aggregation [Gajiwala00, Tapley09]. HdeA is found in a covalently-bound homomultimeric complex [Link97]. HdeA is found at high abundance in vivo [Link97]. HdeB is predicted to have structural similarity to HdeA and the two proteins may heterodimerize in vivo [Gajiwala00]. HdeA has a signal peptide that is cleaved from the mature protein [Wasinger98].
hdeA is acid inducible (pH 4.5-5.5) [Tucker02]. Addition of HdeA suppresses the aggregation of typical chaperone substrates at pH values below 2.5 [Hong05]. In vitro HdeA forms soluble complexes with denatured substrate proteins at low pH but dissociates upon return to neutral pH [Hong05]. Purified HdeA adopts a disordered conformation at pH values less than 3 [Hong05] and exposes hydrophobic surfaces thaty may be involved in binding denatured substrates [Wu08a].
The periplasmic chaperones SurA and Deg P were identified as HdeA substrates under conditions of low pH [Zhang11b]. In vitro, addition of HdeA suppresses the acid induced aggregation and precipitation of SurA [Zhang11b]. In vivo a large amount of insoluble SurA is recovered from acid treated hdeA deletion strains whilst SurA remains soluble in acid treated cultures of wild-type E. coli [Zhang11b]. SurA or DegP assist HdeA in re-folding acid denatured alkaline phosphatase in vitro leading to the suggestion that HdeA functions to protect chaperones such as DegP and SurA which can then use their chaperoning ability to subsequently enhance refolding of other proteins during pH recovery [Zhang11b].
Transcription is negatively regulated by the TorS-TorR two-component signaling system [Bordi03]. Transcription is induced by overproduction of YdeO [Masuda03]. Crl increases hdeA expression via RpoS [Dudin13].
HdeA: hns-dependent expression [Yoshida93a]
Citations: [Liwo99, Holland99, Spory02, Arnqvist94]
Gene Citations: [Arnqvist94, Yoshida93, Tucker03]
Locations: periplasmic space
|Map Position: [3,654,431 <- 3,654,763] (78.76 centisomes, 284°)
|Length: 333 bp / 110 aa
Molecular Weight of Polypeptide: 11.858 kD (from nucleotide sequence)
Unification Links: ASAP:ABE-0011464 , CGSC:33734 , DIP:DIP-47945N , EchoBASE:EB1370 , EcoGene:EG11398 , EcoliWiki:b3510 , ModBase:P0AES9 , OU-Microarray:b3510 , PortEco:hdeA , PR:PRO_000022868 , Pride:P0AES9 , Protein Model Portal:P0AES9 , RefSeq:NP_417967 , RegulonDB:EG11398 , SMR:P0AES9 , String:511145.b3510 , Swiss-Model:P0AES9 , UniProt:P0AES9
Relationship Links: InterPro:IN-FAMILY:IPR010486 , InterPro:IN-FAMILY:IPR024972 , PDB:Structure:1BG8 , PDB:Structure:1DJ8 , Pfam:IN-FAMILY:PF06411 , ProDom:IN-FAMILY:PD065392
GO Terms:
|Biological Process:
|GO:0071468 - cellular response to acidic pH
[GOA01a, Gajiwala00]
GO:0033554 - cellular response to stress [GOA06]
|Molecular Function:
|GO:0042803 - protein homodimerization activity
GO:0051087 - chaperone binding [Zhang11b]
|Cellular Component:
|GO:0030288 - outer membrane-bounded periplasmic space
[GOA01a, Yoshida93, Gajiwala00]
GO:0042597 - periplasmic space [UniProtGOA11, UniProtGOA11a, GOA06]
|MultiFun Terms:
|cell processes → adaptations → pH
|cell processes → defense/survival
Essentiality data for hdeA knockouts:
|Growth Medium
|Growth Observations
|LB Lennox
|Yes [Baba06, Comment 1]
|M9 medium with 1% glycerol
|Yes [Joyce06, Comment 2]
|MOPS medium with 0.4% glucose
|Yes [Baba06, Comment 1]
Curated 16-Apr-2007 by Johnson A , TIGR
Last-Curated 11-Oct-2011 by Mackie A , Macquarie University
|Feature Class
|1 -> 21
|22 -> 110
|39, 87
Gene Local Context (not to scale):
Transcription Units:
10/20/97 Gene b3510 from Blattner lab Genbank (v. M52) entry merged into EcoCyc gene EG11398; confirmed by SwissProt match.
Arnqvist94: Arnqvist A, Olsen A, Normark S (1994). "Sigma S-dependent growth-phase induction of the csgBA promoter in Escherichia coli can be achieved in vivo by sigma 70 in the absence of the nucleoid-associated protein H-NS." Mol Microbiol 1994;13(6);1021-32. PMID: 7854117
Baba06: Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, Baba M, Datsenko KA, Tomita M, Wanner BL, Mori H (2006). "Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection." Mol Syst Biol 2;2006.0008. PMID: 16738554
Bordi03: Bordi C, Theraulaz L, Mejean V, Jourlin-Castelli C (2003). "Anticipating an alkaline stress through the Tor phosphorelay system in Escherichia coli." Mol Microbiol 48(1);211-23. PMID: 12657056
Dudin13: Dudin O, Lacour S, Geiselmann J (2013). "Expression dynamics of RpoS/Crl-dependent genes in Escherichia coli." Res Microbiol 164(8);838-47. PMID: 23867204
Gajiwala00: Gajiwala KS, Burley SK (2000). "HDEA, a periplasmic protein that supports acid resistance in pathogenic enteric bacteria." J Mol Biol 2000;295(3);605-12. PMID: 10623550
GOA01a: GOA, DDB, FB, MGI, ZFIN (2001). "Gene Ontology annotation through association of InterPro records with GO terms."
GOA06: GOA, SIB (2006). "Electronic Gene Ontology annotations created by transferring manual GO annotations between orthologous microbial proteins."
Holland99: Holland RD, Duffy CR, Rafii F, Sutherland JB, Heinze TM, Holder CL, Voorhees KJ, Lay JO (1999). "Identification of bacterial proteins observed in MALDI TOF mass spectra from whole cells." Anal Chem 1999;71(15);3226-30. PMID: 10450164
Hong05: Hong W, Jiao W, Hu J, Zhang J, Liu C, Fu X, Shen D, Xia B, Chang Z (2005). "Periplasmic protein HdeA exhibits chaperone-like activity exclusively within stomach pH range by transforming into disordered conformation." J Biol Chem 280(29);27029-34. PMID: 15911614
Joyce06: Joyce AR, Reed JL, White A, Edwards R, Osterman A, Baba T, Mori H, Lesely SA, Palsson BO, Agarwalla S (2006). "Experimental and computational assessment of conditionally essential genes in Escherichia coli." J Bacteriol 188(23);8259-71. PMID: 17012394
Link97: Link AJ, Robison K, Church GM (1997). "Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12." Electrophoresis 18(8);1259-313. PMID: 9298646
Link97a: Link AJ, Phillips D, Church GM (1997). "Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization." J Bacteriol 1997;179(20);6228-37. PMID: 9335267
Liwo99: Liwo A, Lee J, Ripoll DR, Pillardy J, Scheraga HA (1999). "Protein structure prediction by global optimization of a potential energy function." Proc Natl Acad Sci U S A 1999;96(10);5482-5. PMID: 10318909
Masuda03: Masuda N, Church GM (2003). "Regulatory network of acid resistance genes in Escherichia coli." Mol Microbiol 48(3);699-712. PMID: 12694615
Mates07: Mates AK, Sayad AK, Foster JW (2007). "Products of the Escherichia coli Acid Fitness Island Attenuate Metabolite Stress at Extreme Low pH and Mediate a Cell Density-Dependent Acid Resistance." J Bacteriol 189(7):2759-68. PMID: 17259322
Pasquali94: Pasquali C., Sanchez J.-C., Ravier F., Golaz O., Hughes G.J., Frutiger S., Paquet N., Wilkins M., Appel R.D., Bairoch A., Hochstrasser D.F. (1994). Data submission to UniProtKB on 1994-09.
Spory02: Spory A, Bosserhoff A, von Rhein C, Goebel W, Ludwig A (2002). "Differential regulation of multiple proteins of Escherichia coli and Salmonella enterica serovar Typhimurium by the transcriptional regulator SlyA." J Bacteriol 2002;184(13);3549-59. PMID: 12057949
Tapley09: Tapley TL, Korner JL, Barge MT, Hupfeld J, Schauerte JA, Gafni A, Jakob U, Bardwell JC (2009). "Structural plasticity of an acid-activated chaperone allows promiscuous substrate binding." Proc Natl Acad Sci U S A 106(14);5557-62. PMID: 19321422
Tucker02: Tucker DL, Tucker N, Conway T (2002). "Gene expression profiling of the pH response in Escherichia coli." J Bacteriol 184(23);6551-8. PMID: 12426343
Tucker03: Tucker DL, Tucker N, Ma Z, Foster JW, Miranda RL, Cohen PS, Conway T (2003). "Genes of the GadX-GadW regulon in Escherichia coli." J Bacteriol 185(10);3190-201. PMID: 12730179
UniProt09: UniProt Consortium (2009). "UniProt version 15.8 released on 2009-10-01 00:00:00." Database.
UniProt12: UniProt Consortium (2012). "UniProt version 2012-02 released on 2012-02-29 00:00:00." Database.
UniProt15: UniProt Consortium (2015). "UniProt version 2015-01 released on 2015-01-16 00:00:00." Database.
UniProtGOA11: UniProt-GOA (2011). "Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries."
UniProtGOA11a: UniProt-GOA (2011). "Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries."
Wasinger98: Wasinger VC, Humphery-Smith I (1998). "Small genes/gene-products in Escherichia coli K-12." FEMS Microbiol Lett 169(2);375-82. PMID: 9868784
Wu08a: Wu YE, Hong W, Liu C, Zhang L, Chang Z (2008). "Conserved amphiphilic feature is essential for periplasmic chaperone HdeA to support acid resistance in enteric bacteria." Biochem J 412(2);389-97. PMID: 18271752
Yang98b: Yang F, Gustafson KR, Boyd MR, Wlodawer A (1998). "Crystal structure of Escherichia coli HdeA." Nat Struct Biol 1998;5(9);763-4. PMID: 9731767
Yoshida93: Yoshida T, Ueguchi C, Yamada H, Mizuno T (1993). "Function of the Escherichia coli nucleoid protein, H-NS: molecular analysis of a subset of proteins whose expression is enhanced in a hns deletion mutant." Mol Gen Genet 237(1-2);113-22. PMID: 8455549
Yoshida93a: Yoshida T, Ueguchi C, Mizuno T (1993). "Physical map location of a set of Escherichia coli genes (hde) whose expression is affected by the nucleoid protein H-NS." J Bacteriol 1993;175(23);7747-8. PMID: 8244952
Zhang11b: Zhang M, Lin S, Song X, Liu J, Fu Y, Ge X, Fu X, Chang Z, Chen PR (2011). "A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance." Nat Chem Biol 7(10);671-7. PMID: 21892184
De99: De Biase D, Tramonti A, Bossa F, Visca P (1999). "The response to stationary-phase stress conditions in Escherichia coli: role and regulation of the glutamic acid decarboxylase system." Mol Microbiol 32(6);1198-211. PMID: 10383761
Hayes06: Hayes ET, Wilks JC, Sanfilippo P, Yohannes E, Tate DP, Jones BD, Radmacher MD, BonDurant SS, Slonczewski JL (2006). "Oxygen limitation modulates pH regulation of catabolism and hydrogenases, multidrug transporters, and envelope composition in Escherichia coli K-12." BMC Microbiol 6;89. PMID: 17026754
Hirakawa10: Hirakawa H, Hayashi-Nishino M, Yamaguchi A, Nishino K (2010). "Indole enhances acid resistance in Escherichia coli." Microb Pathog 49(3);90-4. PMID: 20470880
Hommais04: Hommais F, Krin E, Coppee JY, Lacroix C, Yeramian E, Danchin A, Bertin P (2004). "GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coli." Microbiology 150(Pt 1);61-72. PMID: 14702398
Itou09: Itou J, Eguchi Y, Utsumi R (2009). "Molecular mechanism of transcriptional cascade initiated by the EvgS/EvgA system in Escherichia coli K-12." Biosci Biotechnol Biochem 73(4);870-8. PMID: 19352034
Johnson11: Johnson MD, Burton NA, Gutierrez B, Painter K, Lund PA (2011). "RcsB Is Required for Inducible Acid Resistance in Escherichia coli and Acts at gadE-Dependent and -Independent Promoters." J Bacteriol 193(14);3653-6. PMID: 21571995
Marzan13: Marzan LW, Hasan CM, Shimizu K (2013). "Effect of acidic condition on the metabolic regulation of Escherichia coli and its phoB mutant." Arch Microbiol 195(3);161-71. PMID: 23274360
Pesavento12: Pesavento C, Hengge R (2012). "The global repressor FliZ antagonizes gene expression by σS-containing RNA polymerase due to overlapping DNA binding specificity." Nucleic Acids Res 40(11);4783-93. PMID: 22323519
Ruiz08: Ruiz C, McMurry LM, Levy SB (2008). "Role of the multidrug resistance regulator MarA in global regulation of the hdeAB acid resistance operon in Escherichia coli." J Bacteriol 190(4);1290-7. PMID: 18083817
Schneiders04: Schneiders T, Barbosa TM, McMurry LM, Levy SB (2004). "The Escherichia coli transcriptional regulator MarA directly represses transcription of purA and hdeA." J Biol Chem 279(10);9037-42. PMID: 14701822
Shin05: Shin M, Song M, Rhee JH, Hong Y, Kim YJ, Seok YJ, Ha KS, Jung SH, Choy HE (2005). "DNA looping-mediated repression by histone-like protein H-NS: specific requirement of Esigma70 as a cofactor for looping." Genes Dev 19(19);2388-98. PMID: 16204188
Tramonti08: Tramonti A, De Canio M, De Biase D (2008). "GadX/GadW-dependent regulation of the Escherichia coli acid fitness island: transcriptional control at the gadY-gadW divergent promoters and identification of four novel 42 bp GadX/GadW-specific binding sites." Mol Microbiol 70(4);965-82. PMID: 18808381
Weber05: Weber H, Polen T, Heuveling J, Wendisch VF, Hengge R (2005). "Genome-wide analysis of the general stress response network in Escherichia coli: sigmaS-dependent genes, promoters, and sigma factor selectivity." J Bacteriol 187(5);1591-603. PMID: 15716429
Zwir05: Zwir I, Shin D, Kato A, Nishino K, Latifi T, Solomon F, Hare JM, Huang H, Groisman EA (2005). "Dissecting the PhoP regulatory network of Escherichia coli and Salmonella enterica." Proc Natl Acad Sci U S A 102(8);2862-7. PMID: 15703297
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MARYLAND Jewelry Repair
Welcome to An Uncompromising Commitment to Quality and Value!
As one of the countries best jewelry repair centers in the U.S.A., Raymond Lee Jewelers has on-site master jewelers that specialize in repairs ranging anywhere from straight forward to the most complicated jewelry repair in the industry. It is this on site jewelry technology that allows our master jewelers to stay ahead of the competition. Some of this hardware includes, a Laser Star Laser Welder, Signature Engraving machine and Cad/Cam software.
The State of the Art Laser Star Laser Welder
The State of the Art Laser Star Laser Welder makes it possible for our master jewelers to perform repairs to items which before would have been thought of to be way beyond repair. Never before has a repair service center had these capacities. Here are some illustrations of repairs now possible:
- Delicate antique jewelry may easily now be repaired with out risking detriment to valuable heirlooms. Precious and Semiprecious stones that may not take heat will likely be worked on in there mounting with the use of the Laser Welder. Never before was this possible.
- Dented gold bracelets may well be repaired. With the use of the Laser Welder the dents are filled and after it is polished it can look like brand-new.
- One of our most popular repairs are the eyeglass frame repairs. If you have damaged the frames of your eyeglasses, our master jewelers will be able to repair them using the Laser Welder.
The Signature Engraving machine
The Signature Engraving machine is the most technologically sophisticated engraving equipment attainable. The Signature Engraver is a computerized engraver, which means it is 100 percent precise. Our engraver is competent of engraving on most surfaces including:
- all forms of precious metals
- base metals
- glass
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- and very much more
Our most favored engraving service is the inside of rings. Our engraver possesses an attachment that is specific to the inside of rings. There are over 200 fonts to decide from. Another incredibly popular engraving service is watch case back engraving. Easily personalize the case back of a watch using thousands of different styles.
Raymond Lee Jewelers can certainly engrave on all glass surfaces from the tiniest to a magnum bottle of champagne! Personalize all kinds of glass items. Do you hold a image you might like to have engraved on a surface? No problem. Our engraver has a scanner that would be able to do that job. Our master jeweler will scan the photo and engrave it on any surface you choose.
Raymond Lee Jewelers Cad/Cam 3d program lets our designers to produce a computerized model of your creation before production. This is crucial because this enables you to see precisely what your piece is going to look like previous to production. When the computerized 3d model is approved, production begins. Your complete item will look identical to the model. Our custom design professionals are the finest in their arena.
As well as all the individual jewelry services Raymond Lee Jewelers gives you, our repair center also gives all varieties of essential repair. This includes but is not limited to:
- Ring sizing
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Clients from around the country trust Raymond Lee Jewelers with jewelry repair and custom design services. One of our master jewelers or custom design operatives should contact you when your package is obtained to discuss the specifics.
Use our jewelry repair form to inquire about your repair needs.
We repair almost any jewelry item. You may either bring your item to the Raymond Lee Jewelers store nearest you or send in your item via mail. If you choose to send your item via mail, please follow the instructions listed below:
- Download our Repair Form
- Print form and complete all information.
- Enclose form with item to be repaired
- Send item and form, via an insured shipping method, to:
22191 Powerline Road #12b
Boca Raton, FL 33433
Phone: 561-750-7808
Fax: 561-750-8005
Toll-Free: 1-800-329-GEMS
Store Hours - Mon-Sat: 10-5, Sun: Closed
After we make an assessment, we will send you a free estimate.
Shipping to Raymond Lee Jewelers via MY UPS
We recommend shipping via MY UPS. You can take advantage of these features:
- Ship and track packages all in the same place.
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- Save tracking numbers and addresses online.
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- Access saved shipping and tracking information for up to 90 days.
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Jewelry Repair - Online Inquiries Use this form:
Our full service onsite Jewelry repair center will respond to all inquiries as soon as possible.
The best and most accurate way for us to answer all of your Jewelry repair questions is for our certified Jewelry makers to inspect your Jewelry. However, general questions can be addressed by using this form.
Mail-in Repairs Instructions
1. Printing a mail-in repair form
We recommend the convenience and security of using My UPS, however, if you would prefer to mail in your jewelry for repairs here is some helpful information:
If you do not have Adobe Acrobat installed on your computer, click here to install it, then you can download a .pdf version of the jewelry repair form to print out and complete. We must receive printed copy of this form with your jewelry to diagnose your problem or to give you an estimate on repairs or parts replacement to be done. We do not give estimates online.
We recommend the convenience and security of using My UPS, however, if you would prefer to mail in your jewelry for repairs here is some helpful information:
Jewelry Repair Form -
2. Mail-in Instructions
We recommend the convenience and security of using My UPS, however, if you would prefer to mail in your jewelry for repairs here is some helpful information:
The Raymond Lee Jewelers jewelry repair services center recommends that you send your jewelry to us via any method that allows you to both insure and track the package.
IMPORTANT: Do not ship your jewelry in its display box because packing materials will be discarded. After receiving and inspecting your jewelry we will mail, fax or email you a written estimate. All Jewelry shipped out from Raymond Lee Jewelers jewelry repair services center are subject to a shipping and handling charge.
Raymond Lee Jewelers Jewelry Repair
22191 Powerline Road #12b
Boca Raton, FL 33433
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Contact Lenses
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The #1 Eye Doctor Trusted Brand of Contact Lenses.1
With the highest UV protection of any contact lens brand* and unique comfort technologies like LACREON®* and HYDRACLEAR® !, ACUVUE® Brand Contact Lenses help keep your eyes comfortable, moist, and healthy.
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1 In a randomly selected masked survey of 1,002 eye care professionals that included retail and independent doctors from across the US.
** Helps protect against transmission of harmful UV radiation to the cornea and into the eye. WARNING: UV-absorbing contact lenses are NOT substitutes for protective UV-absorbing eyewear such as UV-absorbing goggles or sunglasses because they do not completely cover the eye and surrounding area. You should continue to use UV-absorbing eyewear as directed. NOTE: Long-term exposure to UV radiation is one of the risk factors associated with cataracts. Exposure is based on a number of factors such as environmental conditions (altitude, geography, cloud cover) and personal factors (extent and nature of outdoor activities). UV-blocking contact lenses help provide protection against harmful UV radiation. However, clinical studies have not been done to demonstrate that wearing UV-blocking contact lenses reduces the risk of developing cataracts or other eye disorders. Consult your eye care practitioner for more information.
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ACUVUE®, 1-DAY ACUVUE® MOIST®, ACUVUE® OASYS®, Fresh is Better™, and HYDRACLEAR® are trademarks of Johnson & Johnson Vision Care, Inc.
© Johnson & Johnson Vision Care, Inc., 2013


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Joe Mauer, Twins snap 25-inning scoreless streak, rally to beat M's
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SEATTLE -- Joe Mauer's two-out RBI single in the seventh inning helped the Minnesota Twins rally for a 3-2 win on Friday night, handing the Seattle Mariners their seventh straight loss.
The skinny
The Twins snapped a 25-inning scoreless streak when they scored three runs in the seventh inning as Seattle's bullpen was unable to hold a 2-0 lead after 6 1/3 strong innings from starter Jason Vargas.
But Vargas was just a spectator while Tom Wilhelmsen (1-1) struggled through four batters in the seventh and made a costly throwing error that allowed the tying run to score. Mauer then followed with a single up the middle that glanced off the glove of shortstop Brendan Ryan and allowed Trevor Plouffe to score. The Twins won for just the second time in 11 games.
Carl Pavano (2-2) needed just 69 pitches to get through six innings and pick up his second victory. He gave up a trio of doubles in the fifth inning when Seattle scored both of its runs, but minimized trouble otherwise. Pavano allowed eight hits, but didn't walk a batter and struck out two.
Brian Duensing and Glen Perkins rolled through the seventh and eighth innings before Matt Capps worked the ninth for his fifth save in as many chances.
Seattle lost by one run for the fourth time in five games.
Turning point
Vargas pitched into the seventh, leaving after giving up a one-out double to Chris Parmelee. The double that hopped off the wall in center field was Minnesota's first extra-base hit since the eighth inning of Monday's game against the Angels.
Wilhelmsen replaced Vargas and walked Alexi Casilla and Plouffe. Wilhelmsen looked as if he was going to get out of the inning when Denard Span tapped back to the mound, but instead of throwing home, Wilhelmsen threw wide of second. Parmelee scored because of the errant throw, snapping the Twins' scoreless streak at 25 innings.
Jamey Carroll followed with a grounder wide of first and the only play was a force out of Span at second, allowing Casilla to score the tying run. That was it for Wilhelmsen, who was showered with boos as he was replaced by Charlie Furbush to face Mauer. On a 3-1 pitch, Mauer grounded back up the middle but it glanced off Ryan's stretched glove and trickled onto the outfield grass to score Plouffe.
The Twins had not scored since the eighth inning of Monday's game against the Angels when they scored three times. Minnesota was shut out on Tuesday 4-0, then no-hit by the Angels' Jered Weaver in a 9-0 loss on Wednesday.
Health watch
• 1B Justin Morneau (wrist) missed a third consecutive game.
On deck
• Saturday: at Seattle, 8:10 p.m. Twins RHP Jason Marquis (2-0, 6.23 ERA) vs. Mariners RHP Felix Hernandez (2-1, 2.23).
• Sunday: at Seattle, 3:10 p.m. Twins RHP Nick Blackburn (0-3, 6.64) vs. Mariners RHP Hector Noesi (1-3, 7.83).
• Monday: vs. Los Angeles Angels, 7:10 p.m. Twins LHP Francisco Liriano (0-4, 9.97) vs. TBD.


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As reported by Ron Tillery, the Grizzlies have waived second year shooting guard Jamaal Franklin via the stretch provision this afternoon.
Griz waived second-year guard Jamaal Franklin today using stretch provision, per source. CA story coming…
— Ronald Tillery (@CAGrizBeat) August 31, 2014
Franklin's tenure with the Grizzlies was short, as he appeared in only 21 games last season, while bouncing back and forth between Fort Wayne and Memphis.
"The Grindson," as he was affectionately dubbed by Jason Levien prior to last season, did not help his case to be carried into training camp with his showing at the Orlando Summer League, where he shot 29.2% from the field.
By using the stretch provision on Franklin, the Grizzlies will pay the remainder of his contract ($816,000 per ShamSports) over the next three seasons, with the option to distribute the salary cap hit accordingly.
The Grizzlies freeing up a roster spot lends itself to chatter of a roster move being imminent, but it is important to note that Franklin had to be waived by today's deadline in order to use the stretch provision.


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On my way home from selling some magazines at Powell's, I happened upon a whole street's worth of free piles. First one, then another, then another. The second one was the jackpot, though. I saw the chair, a tall swiveling kitchen chair; it was just what I've been looking for, meant for my youngest son. He loves to swivel and has been asking me for a chair like that. "We'll keep our eyes out!" I've said, meaning exactly this.
I began the delicate process of affixing it to my bike (thankfully achievable, as I had no children with me and the long-tail cargo bike) and, as I tightened the straps, a couple of guys pulled up to load the couch a few feet away. "Great find on the chair!" one of them said. "I wanted it. But you earned it by coming with your bike." He paused, then launching into a rave about the wonders of free piles, and we compared housefuls of free stuff.
"But that's not the only reason to do it," he said. "Getting free stuff means creating less demand for crappy furniture."
"Totally!" I said, riding away with my chair and my over-the-top Portlandia score — an Oregon Kickball Club jersey — and I contemplated.
Having demand for crappy furniture: Isn't that patriotic?
Last Sunday, I listened to a radio show which was mostly concerned with the financial crisis, and whether "we get the banks we deserve." One of the theories was that the crisis occurred not because of a problem in the housing market but because we just wanted to buy so much stuff. Bethany MacLean, author of a book called All the Devils Are Here, said, "One of the great myths about the crisis is that it was a [crisis] of homeownership," Maclean said. "Everybody says this is what happens when you put people into homes and they can't afford to pay them back. This was never about homeownership. Most risky loans that were made were so-called cash-out refinancing so the people could withdraw equity from their homes in order to spend it."
I found myself remembering the times presidents (especially George W. Bush, but this is definitely a bi-partisan campaign) have encouraged us to go out and shop to stimulate the economy. A phenomenon occurred here in Portland, Oregon, the hometown to which I moved back shortly after 9/11: organized flights sent to New York City to shop. They were called "Flights to Freedom" and the message since then has been very much, "it's patriotic to consume."
But here was MacLean, saying that it's our fault that the banking crisis occurred, and not for any other reason than we wanted to buy more stuff. Using that logic, patriotic consumption could be blamed for the crash in our economy and the dip in our GDP. But even typing this statement has me feeling radical and daring. How could it be?
Consumerism has longer-term costs
It's easy to see what the benefits are of buying things, of taking part in what some call the "cult of growth": as more people buy things, GDP increases, businesses get all hot and heavy about the future, they borrow money to make new factories and employ new people to make more things to buy. Then those people have money to buy more things. Then Emma, who owns a house, sees all the great things Lauren has bought with her new job, and she goes out and applies for a credit card (that she can get because of the equity in her home) so she can buy things. And the business owners jump up and down, clapping their hands in glee, while the credit card issuer's CEO pays cash for a new top-of-the-line luxury sedan. And the cycle continues.
But don't these things come with costs? Of course they do, but we're often conditioned to ignore the systemic costs of growth. When we think of our economy growing, we don't typically ask, "but how much carbon will be emitted as those people go to those new jobs and drive to those new shopping malls and how much will that cost us?" When we think of a new housing development, while we may mourn the pretty, wild spaces that are being paved over and the developers may have to pay to have the little red-tailed frogs moved to another wetland, we still do not ask if the disruption to the ecosystems will cost us money in two or three decades. We think of the immediate costs and benefits and we abstractly mourn the immediate loss of pretty, old buildings and swampland. But we don't look very far down the road.
And consumerism has its personal costs, too.
Consumerism has been called an addiction, one that "saps our financial resources, well-being, and hope." In my home, the years we have been more consumptive than creative; when I have spent more of my time acquiring things than making them, and when I have made and spent the most disposable income on stuff; are the ones I regret most. My husband and I still argue over the money spent on our wedding and honeymoon, money we really shouldn't have spent, and we've talked here before about how arguments over money break up a lot of marriages.
That's really only a start. In my family, buying stuff doesn't only lead to arguments over money, but arguments over stuff. We argue a lot about how to store our stuff, who has too much stuff, whether we should throw stuff away, whose fault it was stuff was ruined/stolen/lost, and most importantly, what the purchases say about our values. So far, our marriage has managed to stay together, but I know plenty of families who break up largely because of differing consumer values; this has a huge cost on the system, from the environmental costs of keeping two separate households, to the increased likelihood the family members (especially the mother and children) will end up in poverty and creating a drain on the system, to the costs of the judicial system to deal with all those divorces.
The more we want, the more hours we must work, taking time away from family and decreasing both well-being and health. I'm sure you could work with me to enumerate the personal costs of consumerism. They're almost unlimited.
This chair is a huge deal. Do I dare sit in it?
When I think about it back at home, this chair — and the others at my kitchen table — are pretty radical. I'm rejecting the idea that I must buy a new chair from IKEA or a furniture store, one that's made in a factory by workers who earn a wage (living or no), and purchased at a retail store whose workers are also paid. I brought it home on my bike, oil companies and American car manufacturers be damned. I did not create any new demand for new things.
But I saved an inestimable amount of future costs, from the disposal of the old chair to the environmental costs of manufacturing and shipping, to the health costs of workers who manufacture and ship these products, right down to my own feelings of well-being and not-argument. I don't have to ask my husband for money to buy a new chair; we won't argue about money, today.
I set my five-year-old up in "his" "new" chair, and ask him what he thinks, and as the smile breaks over his face, I think, "I'm raising a radical kid. Poor thing," and I have to admit I'm pretty proud of his delight.
GRS is committed to helping our readers save and achieve their financial goals. Savings interest rates may be low, but that is all the more reason to shop for the best rate. Find the highest savings interest rates and CD rates from Synchrony Bank, Ally Bank, GE Capital Bank, and more.
This article is about Being Frugal, Being Frugal, Consumerism, Economics


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Mobile games offer marketing prospects
17 May 2013
WHITING: Over half of US tablet and smartphone owners play games on their devices and one in ten does so more than once a day, new research has revealed.
The online survey, by Harris Interactive for
, polled 2,058 adults and found that 51% of mobile owners play games on occasion, with 11% playing more than once a day, 21% at least once a day, 41% at least once a week and 10% once a month or less.
Separately, the Wall Street Journal has reported that users spend on average two hours a day on apps, including games, and this is set to grow.
This is a trend that mobile marketers can exploit, according to Brendan O'Kane, chief executive of mobile analytics group OtherLevels.
In an article for
The Fast Company
, he suggested that they could utilise the "gamification" employed by the wider gaming industry to good effect.
This could include introducing points scoring into non-games areas of marketing, such as book sales, which he said could drive brand awareness and sales, as well as encouraging users to spend longer on site.
"Fun can blur the line between marketing and entertainment, creating a more compelling experience," he declared.
But spending a good deal of time on gaming can be expensive. Jackie Warrick, senior savings adviser at CouponCabin.com said: "App purchases, even though they're often low priced, should be factored into an overall entertainment budget."
And the survey showed that while 61% of American adults who have paid to download a game over the last year spent no more than $10, 11% had spent over $50.
There is the additional problem of children purchasing apps without permission or by mistake, with 12% of adults surveyed saying their children have bought a game app by mistake, and 10% intentionally without their permission.
Data sourced from CouponCabin, The Fast Company; additional content by Warc staff
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SOLDSOLDWestern Mountaineering Summerlite 6' left zip for saleSOLD shippedI just paid $44 to have it professionally cleaned at Rainy Pass repairs (they are the best at cleaning) last month, unused since.I purchased it on the forum but my wife decided she didn't want it (we never used it).
Edited by bestbuilder on 06/06/2013 16:48:54 MDT.
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The Mark Bradford Exhibition Opening
Thursday, May 26, 2011, 6:30–9 pm
Tickets $20, MCA members FREE*
Buy Tickets Online
Call the MCA Box Office, 312.397.4010
*Members must show their membership cards to receive free entry.
Upgrade! Purchase an MCA Membership to receive your FREE members' tickets to the Mark Bradford Opening, and receive invitations to Members' Openings all year long!
For more information please contact Monica Wojtyna at 312.397.3831 or [email protected].
This exhibition is organized by the Wexner Center for the Arts, The Ohio State University.
Major support for this exhibition is provided by the Andy Warhol Foundation for the Visual Arts and Resource Interactive.
Significant contributions are provided by The Broad Art Foundation, the Nimoy Foundation, Nancy and Dave Gill, and Toby Devan Lewis.
General support for the Wexner Center for the Arts is provided by the Greater Columbus Arts Council, The Columbus Foundation, Nationwide Foundation and the Ohio Arts Council and by the Corporate Annual Fund of the Wexner Center Foundation and Wexner Center Members.
Support for the Chicago Presentation and The Mark Bradford Project is generously provided by The Chicago Community Trust, The Joyce Foundation, and Sara Lee Foundation.
Additional support is provided by Cari and Michael Sacks, Helen and Sam Zell, Robert and Sheryl Bellick, The Broad Art Foundation, Shawn M. Donnelley and Christopher M. Kelly, Jack and Sandra Guthman, Kovler Family Foundation, Liz and Eric Lefkofsky, Susan and Lew Manilow, Kim and Brad Keywell, Marilyn and Larry Fields, Gary and Denise Gardner, The Good Works Foundation, Nora Daley Conroy and Sean Conroy, Susan and Larry Marx, Linda Johnson Rice, and Desiree Rogers.
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Special meeting tonight to discuss plans for Penzance harbour
Posted: June 17, 2013|
A SPECIAL meeting is being held in Penzance tonight to thrash out the town's view on plans for the redevelopment of the harbour.
County Hall has sent a business case to Minister for Transport Norman Baker which outlines plans to dredge the harbour and possibly introduce rock armour.
The minister has already said he would be keen to hear the views of the town council on the plans, especially on the controversial use of rock armour.
Penzance Town Council has organised tonight's discussion, which is open to the public to attend, "to consider a response to Cornwall Council's submission to the Department for Transport".


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Actress participates In Client Appreciation Night For
Lee Mather Co., Realtors at Village Theatre
Marilyn Monroe made a glamorous return to Coronado Thursday night when she surprised
guests at the Village Theatre during a local business's client appreciation night.
Courtesy of Brent Haywood Photography.
Nearly 200 people turned out Thursday evening as guests of Lee Mather Co., Realtors to see a special engagement of the film, "Some Like It Hot," starring Marilyn Monroe, Tony Curtis, Jack Lemmon and the historic Hotel del Coronado.
Nothing says fun like Marilyn Monroe. Here she is seen with the partners at Lee Mather Co., Realtors (from left) Mike Herlihy, Tom and Debbie Riddle. Courtesy of Brent Haywood Photography.
In the middle of the film, and to the surprise of guests, Marilyn herself sprinted down the aisle of the theatre screaming, "Wait for Sugar, wait for Sugar!" – an iconic line borrowed from the film. In hot pursuit was Frankie Montoya, manager of the Village Theatre, waving his flashlight. It was a classic comedy routine and the crowd cheered with approval.
Christian Esquevin, executive director of the Coronado Public Library, had his hands
full when Marilyn Monroe spotted him. Courtesy of Brent Haywood Photography.
After the movie Marilyn flirted and posed for photos with guests as they left the theatre. Marilyn, in this instance was Hollywood-based, internationally-known tribute artist, Holly Beavon, who has performed numerous times at the Hotel Del over the years and hundreds of Marilyn Monroe tributes and special occasions.
Marilyn, up to her tricks, found a willing victim in Melvin McBroome, a 32-year Army Special Forces veteran. "I loved every minute of it," said McBroome. Courtesy of Brent Haywood Photography.
"Too much fun," said Debbie Riddle, co-owner of Lee Mather Co., Realtors. "We wanted to do something very different, and very special for our many clients and friends in the community," said Riddle, "and this certainly was a night to remember."
The restored Village Theatre was the perfect setting for a special screening of "Some Like It Hot" and a return to Coronado of Marilyn Monroe. Courtesy of Brent Haywood Photography.
Riddle, along with partners Mike Herlihy and Tom Riddle, said they hoped this would be the first movie appreciation night of many. "We've had the idea of a movie night for years. Now that we have this beautifully-restored Village Theatre, we'll do more," she said.
Rob Talbot (left) and Jim Nelson of Lee Mather Co., Realtors didn't seem to
mind fighting for Marilyn's affections. Said Talbot, "They don't
grow 'em like that down in Texas." Courtesy of Brent Haywood Photography.
Riddle was quick to thank Lance Alspaugh and Vintage Cinemas for their cooperation, and said LMC's next film could air in March - "Chocolat," starring Juliette Binoche and Johnny Depp.
Village Theatre manager Frankie Montoya participated in a slapstick comedy routine as he
pretended to chase Marilyn Monroe down the aisles of the main screening room in the
Village Theatre. The crowd loved it. Courtesy of Brent Haywood Photography.
Lee Mather Co., Realtors has been serving Coronado since 1953. For more information call (619) 435-5200 or visit the LMC website at www.leemather.com.
This story was produced by Joe Ditler and Part-Time PR,
serving all of Coronado's publicity needs.
For more information call 619.435.0767
or write firstname.lastname@example.com.
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