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The children, grandchildren and great grandchildren, along with other family members and friends, will gather to celebrate Tom and Vera's 60 years of marriage together, and thank them for making us all a family.
Tom and Vera were married in Standwood, Wash., then made their home in Green River where they raised their four wonderful children. In 2008, they moved to Lower Miller Creek where they now reside and enjoy many new friends.


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I used to have a heck of a time getting my driver's license out of that little plastic covered compartment in my wallet, until I did this... I took a piece of scotch tape about an inch long and pressed the tip of it to the front side of my license, then folded it over and pressed the other tip to the back side of my license, and pressed it together. Now I have a "tab" that sticks out of the wallet compartment and I can easily grab it and pull my license out when needed. Works like a charm!
I used "Pin as tab" in Firefox 4 to fix my daily nutrition tracker page.This way, my nutrition tracker is always there one click away when Firefox opens up. It is less time to add food, and I am more likely to track. ("Pin as tab" is also useful for gmail and facebook.)21617
By clicking links (mostly anything underlined) with the mouse button on the right and choose "open link in new tab" allows you to stay where you are and go to the link too. The new link will be open in another tab and you can click between tabs. (tabs are at top of your browser)I like to right click on stuff (ie. blogs I want to comment on) and go back after I'm finished earning points. You can have many tabs open at once.
My best friend who is a track and cross country runner told me about doing the Lying Abduction (or Adduction) exercise while you read. But you can do it while watching TV as well. I love doing this because then I feel more time-efficient!

subset: commoncrawl


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Glamour Kills Unicorn Forever T-Shirt
Item # 237124
Stash Points: 2,995
What is this?This is the number of points you get in The Zumiez Stash for purchasing this item. Stash points are redeemable for exclusive rewards only available to Zumiez Stash members. To redeem your points check out the rewards catalog on thestash.zumiez.com.
Keep things interesting and always in style with this colorful tie dye t-shirt that features a unicorn and sun graphic with "Stay Weird" lettering.
|More Details


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NEW YORK (MarketWatch) — U.S. stock futures moved lower on Wednesday as a disappointing GDP number outweighed positive reports on private-sector job gains, which had briefly lifted stocks into the green.
Investors await the conclusion of a two-day Federal Reserve meeting and a batch of other data. Technology stocks are expected to take more heat after Twitter Inc. and eBay Inc. disappointed with earnings reports.
Discuss key earnings announcements before and after results come in. Learn more
Futures for the S&P 500 US:SPM4 fell 2.5 points to 1,870.40, while those for the Dow industrials US:DJM4 lost 3 points to 16,464. Deeper losses were seen for the Nasdaq 100 US:NDM4 down 9 points, or 0.3%, to 3,554.25 as Twitter and eBay came under premarket pressure.
Private-sector hiring picked up in April, with employers adding the most jobs in five months, according to data released Wednesday morning.
Growth in the U.S. economy nearly ground to a halt in the first quarter, a bout of weakness spurred by one of the worst winters in years. Gross domestic product rose at an annual rate of just 0.1% from January through the end of March, the weakest performance in three years, according to a preliminary estimate by the Commerce Department. Economists surveyed by MarketWatch had forecast growth to slow to a seasonally adjusted 1% from a 2.6% clip in the final three months of 2013.
Investors will have to wait awhile for the event of the day — the results of the Fed's latest policy-setting meeting, in which the central bank is once again expected to reduce its bond-buying purchases. Those results will be released at 2 p.m. Eastern Time. Read: No fireworks expected at Fed meeting
Also on the calendar is the Chicago PMI survey for April, due at 9:45 a.m. Eastern Time. Economists polled by MarketWatch are expecting a reading of 56.9, versus 55.9 in the prior month.
Stocks on Wall Street closed moderately higher on Tuesday after several companies beat estimates. The S&P 500 SPX, +0.01% ended the day 8.9 points, or 0.5%, higher at 1,878.33, while the Nasdaq Composite COMP, -0.09% finished up 86.63 points, or 0.5%, to 16,535.37, helped by earnings-driven gains for Merck & Co. MRK, +1.57%
Nasdaq could see pressure, thanks to eBay, Twitter
But tech stocks looked set to have a tough time repeating that performance, with Twitter TWTR, +4.57% already down 12% in premarket trade, following losses late Tuesday. The microblogging company beat revenue forecasts, but disappointed with its average monthly users tally for end-March. Read a recap of Twitter's earnings call with analysts
And eBay EBAY, -0.12% shares fell 4.8%, after its first-quarter earnings topped expectations but its outlook was viewed as lackluster.
Shares of Panera Bread Co. PNRA, -1.00% fell 5.2% after the company's second-quarter outlook fell short of Wall Street estimates.
Software giant SAP seeks growth in China
SAP's president for Greater China, Mark Gibbs, tells the WSJ's Juro Osawa how the German business-software maker is helping major Chinese clients manage their operations.
Ahead of the bell, WellPoint Inc. US:WLP reported adjusted first-quarter earnings above expectations with EPS coming in at $2.30, compared with estimates of $2.10. Shares rose 2.1% premarket.


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ESSEX — As of July 1, those caught by police in Vermont with an ounce or less of marijuana will be subject to a ticket, not a criminal charge.
Gov. Peter Shumlin signed the bill into law Thursday while speaking to a group of public defenders at their annual conference at the Inn at Essex. The law makes Vermont the 17th state to either decriminalize or legalize marijuana.
Shumlin called it a more common sense way to deal with possession of marijuana. When Vermonters do abuse marijuana, lets make sure its a traffic ticket kind of fine and it doesnt affect the rest of their lives, he said.
Sen. Joe Benning, R-Caledonia, a lawyer who pushed for the bill partly based on his own experience, warned the audience of public defenders that the drug is still illegal. We have not legalized marijuana. Please dont tell your clients that, Benning said.
Benning said he was arrested as a teen in 1975 when a house where his rock band was practicing was raided. He said he wasnt smoking marijuana, but had to go through a protracted expungement process to clear his record.
Police and some prosecutors argued during the legislative debate that decriminalization will send the wrong message that marijuana use is OK.
Bobby Sand, a former Windsor County states attorney who now works for the state Public Safety Department, argued that the message it sends is: we have the capacity to change. Thats a very powerful message.


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The new 2015 Halloween costume range has arrived! Zombies, skeletons and more, our latest range also includes kids zombie Halloween costumes and wide variety of fancy dress masks & halloween wigs.» All Halloween costumes
The new 2015 Christmas costume range has arrived! Santas, nativity costumes and more, our latest range also includes funny Christmas costumes, Christmas skinsuits and & even Christmas hats.» All Christmas costumes
Here at Mega Fancy Dress we have everything you could possibly need for a brilliant themed night out!» All ladies costumes
Whether you're 16 or 60, nobody could fail to look cool in one of our themed mens costumes.» All mens costumes
Whether you're 16 or 60, nobody could fail to look cool in one of our themed kids costumes.» All kids costumes
Home > Ladies Costumes > 70s Costumes > Punk Rocker Lady Tattooed Biker 70s 80s Fancy Dress Ladies Costume
Ladies' Tatooed Punk Rocker Fancy Dress Costume
Oi, Oi, Oi ! Fight for your right to party with this fabulously rebellious fancy dress costume that perfectly captivates the look of a 1970s punk rocker
Included is a flesh coloured long sleeved top covered in fantastic printed tattoo detailing giving the illusion that you've been under the needle more than just a few times, a short leather look crop top worn over the tattoos, a pair of matching flesh coloured leggings again decorated with printed detailing and completing the costume is a short black leather look skirt decorated with printed silver stud detailing to the waistband.
You'll be the prettiest punk rock princess at any party when you wear this amazing costume, perfect for a 1970s themed fancy party.
Flesh coloured top decorated with printed tattoos
Leather look crop top
Flesh coloured leggings with print
Short black leather look skirt and printed silver studs.
All items paid before 5pm will be dispatched the same working day Monday - Friday.
Here at Mega Fancy Dress we aim to get your goods delivered to you Mega Fast! Most of our customers do receive their items the next working day however this is not guaranteed unless you opt for next day delivery at checkout. 1st class post generally takes 1-3 working days.
All our costumes are instock and ready to post. To guarantee your item the next working day please pay before 5pm and opt for next day delivery.
For standard items we use Royal Mail and for larger items we tend to use UPS.
Customers will automatically receive an e-mail confirming dispatch.
If any item is returned back to us after attempted delivery then we reserve the right to charge a repostage fee or a refund subject to our returns policy.
Please choose the Saturday Delivery service at the checkout.
If your question is not answered here then please contact email@example.com
We accept Debit, Switch, Solo, Mastercard, Visa Cards and Paypal. You can also pay by card over the phone.
It's our top priority to ensure that our customers' transaction data is kept secure at all times, which is why we use Sagepay who comply with the Payment Card Industry Data Security Standard (PCI DSS).
Yes we do please use Royal Mail delivery options at check out.
Yes at checkout you will have the option of changing the delivery address.
Each product will have have a size chart which should be a good guide. Please note every costume is different and we are unable to guarantee exact measurements.
We recommend all costumes are dry cleaned or are gently hand washed.
Yes all prices where applicable include VAT at 20%
All orders prior to payment can be cancelled and will not be posted until payment received.We offer a quick turn around in order to get you your costume fast, therefore once an item is paid for we are unable to change, add or cancel an order once payment has been received. If you have placed an order and no longer want the costume you can refuse delivery, or return the costume back to us for a refund subject to our returns policy


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Watch what happened when Adam Lambert was almost voted off American Idol last night:
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text:
Contreras to Live out Dream Thursday at Gulfstream
Contreras to Live out Dream Thursday at Gulfstream
HALLANDALE BEACH, FL - When he was a 16-year-old bug rider in his native Mexico, Luis Contreras would "dream about riding at Gulfstream."
"I'd watch the races and I'd say to myself, 'One day I'm going to be there.' It was one of my favorite tracks."
Nearly 10 years after beginning his career, Contreras has arrived at Gulfstream and in a big way. The 25-year-old jockey comes to Gulfstream just days after setting a single-season earnings record at Woodbine with more than $11.2 million in earnings, breaking the previous mark set in 2003 by Todd Kabel. Contreras makes his debut Thursday at Gulfstream in the last race for trainer Mark Casse.
Contreras, the regular rider for Inglorious, winner of the $1 million Queen's Plate Stakes, also became only the second rider in Woodbine history to win 200 or more races in one meet.
"It's been an amazing year," said Contreras, who moved to North America in 2007. "But I can't wait to spend my first winter at Gulfstream. I have my ticket and my family and I are ready to come down.
"I want to take a chance and try it at Gulfstream. I think people know about how hard I work and it's a great opportunity for me."
Contreras enjoyed four consecutive campaigns of 100-plus win seasons in Mexico before moving to Northern California in 2007. He rode his first U.S. winner Feb. 1 of '07 at Golden Gate Fields. In 2008, Contreras moved to Sunland Park in New Mexico, where he won the riding title in 2009-2010. His real success started in 2009, however, when trainer Steve Asmussen decided to send a second string to Woodbine and named Contreras as his first-call rider. Contreras won 67 races that year and $2.8 million in earnings, finishing ninth in the overall standings.


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Much to be undone-A A +A
Tuesday, January 21, 2014
THE windows and doors of this small house are all boarded up. I am usually partial to airy open spaces but two weeks of this wet and now windy weather make me wish that I am in an Ivatan stone house instead of this hut made for tropical weather. But then I am pretty sure I would say the opposite thing in a few months. The searing heat of the windless summer will make me want to tear down the walls of this house and pine for the stormy weather of the past week.
Wrapped in Grey
Welcome to the weather of extremes brought about by climate change. I would gladly endure the tolerable inconvenience of the dampness and the mud, and alternately the heat if these were all there is to it. But we know painfully well that the past few years have proven the deadly effects of these unnatural natural events.
We were on the edge this week as the Cagayan de Oro river threatened once again to swell with the incessant rains brought in by the first storm after the deluge that was Yolanda. And we remain on alert as I write this as the movement of the storm toward the Davao region gather heavy rainclouds over most of Northern Mindanao.
To say that not much has changed about our regard to the danger posed by weather systems would be wrong. Information about various weather tracking models, rainfall amount, and water levels in our major rivers are now literally at the tip of our fingertips. Thanks to the public scientists who make this information available to everyone which are now being used diligently by wired citizens for safety.
Our reputation as the social media capital of the world complements these developments. Vital information are quickly passed around among family and friends and these emerging social practices go a long way in efficient disaster response as well as provide assurance for worried relatives continents away.
But there is also a danger with these new coping mechanisms that have the tendency to reinforce one aspect of the problem that make us so vulnerable to all these challenges brought about by climate change.
We privately adjust to the impending floods, landslides, and storm surges leaving those who do not have access to information and resources at the mercy of the elements and an equally harmful condition, that of government ineptitude.
If there is any major lesson that can be culled by the destruction of Yolanda and before that Pablo and Sendong is that our survival and resilience not just as families but as a community in the face of these natural calamities depends much on how we nurture our collective ties to each other. Playing a central role towards these efforts, should be our local governments.
It was an encouraging development that in the past local elections, how our elected officials responded to these natural disasters was at the forefront of public discourse. I dare say that it was the defining issue in the election results and continue to be so for the elected local officials as they fulfill their terms. By all indications, it is also going to be the case for the upcoming national elections in 2016 after the debacle of Yolanda and the pathetic response of the national government.
But there is also great disappointment in how some politicians have responded to this challenge. They are now investing in making themselves visible in high-profile post-disaster situations such as relief and rescue operations when the point of their responsibility is to avoid precisely these very situations from developing.
The key here is engendering community preparedness down at the level of the barangay and when the situation finally calls for it, make the resources available for pre-emptive evacuation possible. It is encouraging to note that the current provincial government has proven their capacity for the latter but might need to consider placing greater emphasis for the former.
But ultimately, a collective soul-searching must be undertaken. For instance, to make sense of Sendong and Pablo and prevent similar disasters from happening again, we must probe the kind of political economy that has created silted rivers and denuded forests. Unregulated expansion of agricultural capitalism and unabated logging operations in the uplands all undertaken for private profit are just some of the ignored contexts that create the conditions for disaster.
If we are to really be resilient in the true meaning of the word and not just as battle-hardened survivors of one naturally calamity after another, then we are required to take a long hard look about the way we order our societies. Among the community of nations, this same challenge is posed to industrialized nations who have benefitted from the catastrophic burning of fossil fuels at such a scale so as to alter global temperatures in order for them to afford their high standards of living. There is no stronger argument for a return to a more collective mode of living in the face of the revealed consequences of how the wanton profit-seeking of a few has wreaked havoc to our shared existence on this singular earth.
In the time of extreme weather events brought about by climate change, much is to be done and undone. But at stake are our very lives especially here in the Third World made more vulnerable by poverty and a backward political economy.
(Arnold P. Alamon is an Assistant Professor IV, Sociology Department, Mindanao State University-Iligan Institute of Technology.)
Published in the Sun.Star Cagayan de Oro newspaper on January 21, 2014.
Country News
Cagayan de Oro
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text: 'Superwheat' could boost yields by 30 percent Science 12 May 13 by Duncan Geere WheatJon Bunting / CC BY 2.0 Agricultural botanists have combined an ancient variety of wheat with a modern one in an attempt to increase production, and early results show a significant improvement.The National Institute of Agricultural Botany developed the new strain without the use of genetic modification. Instead, they used cross-pollination and seed embryo transfer technology to grant the modern what some of the characteristics of a 10,000-year-old strain.The resulting crop seemed "bigger and stronger" than currently-used wheat varieties. The researchers believe that the eventual outcome of the process could be an increase in productivity of 30 percent.However, these are just the results of early trials. Five years of tests and regulatory approval will be needed before farmers can begin to plant the new crop.One in five of all the calories consumed around the world come from wheat, so the research could have a significant effect on food security around the globe. The last 15 years have seen little growth in wheat harvests in Britain. Comments Latest on wired.co.uk


text: Bayville ShopRite (Ilya Hemlin, Townsquare Media) [ Shop Rite Stabbing Victim Faces Drug Charges By Rosetta Key April 20, 2012 Remember the story about the Bayville Shop Rite worker who was stabbed last month? Well, in a bizarre turn of events, police are now reportedly asking the public's help in locating him. Read More|Comment Category: Briefs, News, Ocean County News Tags: Bayville, Cocaine Charges, Noah Jackson, ShopRite, Stabbing Victim, WOBMFM Send to a friend! Share on Facebook Share on Twitter Pin it! Reddit This! Share on Tumblr!


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In my continual quest to use eco-friendly cleaning and personal products, it can be difficult at times to satisfy the men in my family. The market for men's grooming products has certainly opened up since I was younger, with all kinds of nice-smelling lotions, deodorants and rugged concoctions aimed at guys. However, many of these products are loaded with sulfates and petrochemicals, something that I personally don't want slathered all over my beloved husband.
Fortunately, I have no need to search anymore, now that I've been introduced to the natural grooming products from ManCave.
ManCave Original set, which includes Shower Gel, Moisturizer, Face Wash, Caffeine Shampoo and Deodorant.
ManCave products in bulk "buckets" with discounts and free shipping, so no worries about running out for a while.
The ManCave line of products would make a great gift for Valentine's Day, or even just a starter for a new year of healthier living.
@ManCave or via the ManCave Facebook page.
Disclosure: I received sample products from ManCave for review purposes. All opinions are my own.
January 6, 2014
Natural Grooming for Men from ManCave
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Since 1947
(based on 24 reviews)
Ratings Distribution
5 Stars
4 Stars
3 Stars
2 Stars
1 Stars
of respondents would recommend this to a friend.
Best Uses
Reviewed by 24 customers
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Great Gift!
By Diannie
from Columbus, IN
About Me Avid Cook
Comments about Gas Stove Extra Deep Burner Covers- Set Of 2:
I bought these covers for my daughter. She has a small kitchen, so extra space really matters. She can now use the top of the stove as an additional surface top.
Bottom LineYes, I would recommend this to a friend
Was this review helpful? Yes / No
- You may also flag this review
stove top
By sonny
from west chester pa
love everything I get
Extra space.
By KW in Bklyn
from NY
About Me Casual Cook
Love stove covers second time ordering them,still have the first ones just wanted to change color.great idea.
(5 of 5 customers found this review helpful)
Poor construction
By Stefanie
from California
I purchased the extra deep covers and was disappointed that the metal surface on the sides, front and back was not smooth, which looks even worse when sunlight hits my stove in the morning. They look super cheap and do not fit well despite the dimensions indicating that they would.
Bottom LineNo, I would not recommend this to a friend
(1 of 1 customers found this review helpful)
I would buy this product again and again
By Tam
from Victoria, Tx
These make the stove looks great and are a perfect fit.
Just what my mom wanted!
By ShelliG
from Atlanta, GA
My mom could not find the deep covers locally and had mentioned it on several occasions. I was very pleased to find these and was happy with the color and quality when they got here.
Great cover-up!
By Catalog Queen
from Milwaukee, WI
About Me Rarely Cook
I rarely cook so I wanted something to cover the gas burners on my stove so I wouldn't have to clean them very often. These covers are perfect! Not only are they attractive, they provide extra counter space when the stove is off. Should have bought them years ago!
Good find
By Mellow Yellow
from Washington, DC
Easy to use, covered gas burners well.
(2 of 2 customers found this review helpful)
Exactly what I wanted. Great Quality!
By Andre
from Baltimore, MD
My kitchen is so small I need half my stove for other appiances. I've already tried baking at 400 and the covers themselves did not get hot - a feature I was grateful for considering the Forman Grill I had on tope. One thing I did do I removed the knobs to the burners I covered so as not to put them on by mistake and I put one on top of the other for extra strength.
Deep burner covers
By Lib
from New York, NY
Very flimsy covers. They scratch easily.


text:
Cultivating Diversity in Fundraising
(If any tax is payable it will be calculated and shown at checkout.)
Preview (read now) Add to my own site Give this ebook to a friend Add to my wishlist Author's page Publisher's page
moreAn important roadmap for fundraising in today's multicultural communities
Raising money in today's diverse communities is a growing challenge for fundraisers and philanthropists, requiring thoughtful strategies, successful collaborations, and a respectful understanding of people's differences.
In this groundbreaking new book, the author examines today's four major ethnic groups-African American, Asian American, Hispanic/Latino, and Native American-in terms of their diverse histories, traditions, and motivations, and then applies this information to the proven components of successful fundraising. The result is a timely and important look at how fundraisers can use an understanding of ethnic differences to create a vibrant and balanced nonprofit center through both individual and collective efforts.
In clear, easy-to-understand language, Cultivating Diversity in Fundraising answers the following critical questions:
* Who are diverse donors?
* What are their charitable traditions and interests?
* What fundraising methods will be successful in diverse communities?
* What can fundraisers do to include more diversity in fundraising efforts?
Designed as a guide to fundraising as well as a strategic update for existing fundraisers, this book should be required reading for anyone working in today's nonprofit sector. less
Wiley; March 2002
313 pages; ISBN 9780471226017
Read online, or download in secure PDF format
Title: Cultivating Diversity in Fundraising
Author: Janice Gow Pettey
313 pages; ISBN 9780471226017
Read online, or download in secure PDF format
Title: Cultivating Diversity in Fundraising
Author: Janice Gow Pettey
Buy, download and read Cultivating Diversity in Fundraising (eBook) by Janice Gow Pettey today!
More Business
Getting to Yes 2011 US$ 12.99 240 pages
The 4 Disciplines of Execution 2012 US$ 19.99 256 pages
The Smartest Guys in the Room 2013 US$ 13.99 480 pages
Outliers 2008 US$ 9.99
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Ordering for a Team?
Let our Team Division Help!
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From the Riviera to the kiddie pool, your baby will have the cutest swimwear around with the Bummis Clownfish Swim Diaper Cover.
For more information on swim diapers, read Understanding Swim Diapers
worth it
This worked perfectly for my Son on his first day of baby swim class. The Clownfish were all the rage!
Happy Mom
Anytown, USA
Fit: Feels true to size
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He pooped!
My little 3 month old grandson gave the swim diaper a real trial, and it worked great! It was easy to wash out with some soap.
Pam S
San Diego CA
so far very happy
We used it only once but I'm very happy so far with the product. Doesn't hold the pee but that's obvious right? :) I'll believe it holds poop in though. Hopefully won't have to check that on public pool :) Good stuff!
Western Mass
Get an alert when we add new styles of Bummis! Simply sign up and we'll notify you.
Bummis began as the proverbial "kitchen table business", started by three mothers who were using cloth diapers on their own babies and were inspired to create the products they themselves needed. Since then, Bummis has grown and prospered while staying true to the vision that inspired its inception and the values that fuelled its growth. We believe that once parents see how easy it is to use cloth diapers, they will use them! So we focus on making it easy – through the products we design and distribute, the washing and using information we disseminate and the customer service we are so passionate about.
We produce everything we can in our factory in the Montreal area, and we use North American components as much as is humanly possible. For the products and components unavailable to us here in North America, we work with our long-time, reputable partners in the UK and Pakistan. Everything – both manufactured here and imported - is tested for non-toxicity and also where relevant for good biodegradability standards.
As soon as we were able to do so, we switched our cloth diapers to GOTS certified organic cotton. Even though our prefolds by the dozen are now slightly more expensive than non-organic options, we feel that it is completely worth it – both for us and for consumers. Using organic cotton further reduces the carbon footprint of using cloth diapers, and it protects everyone in the chain – from grower to sewer to baby. It also protects the earth from the chemical overuse that threatens soil, air, water and biodiversity, and promotes a more sustainable way of life.


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Rimrock Promotions
876 Senora Avenue
Billings, MT 59105
Phone/Fax: (406) 259-3114
Mobile: (406) 860-3915
Rimrock Promotions, the region's number one Home Show Producers, will be holding the 22nd Annual Home Improvement Show at the "Expo Center", Montana's largest exhibition facility.
The show is free to the public and will open Friday, September 11th at noon and run through Sunday, September 13th at 5:00 p.m. Over 400 exhibits were exposed to over 20,000+ people attending the "2014 Show", making it the largest attended Home Show in a five state area. With Spring right around the corner, NOW is the time to exhibit your products and services.
Over $30,000 is allocated in advertising and promoting the show, along with innovative grand prizes.


text:
Gill Hiking Boots Junior
- 5mm neoprene for warmth
- Non-slip razor cut soles
- Reinforced instep, toe and heel areas for maximum support and durability
- Ankle support
- Non ferrous zip
- Velcro zip lock tab
- Neoprene gusset behind zip to reduce water ingress
- Flatlocked seams for comfort
For delivery cost, please select "Estimate Delivery" on the product page or in the shopping basket. Due to the complex nature of our product range and delivery services the actual charge may vary. If the delivery cost is any different to the charge estimated on your order, you will always be notified and the delivery service updated or the order cancelled. No payment is ever taken until your order is dispatched.
Export delivery charges and options will be quoted by email to you, for your approval.


text:
Speedblast™ Abrasive
NOTE: If you are unable to view this video in your browser, click here
Speedblast™ is a clean, safe, economical and environmentally responsible replacement for silica sand, slags, and staurolite.
Low Dust!
Tough, durable garnet grains produce far less dust when blasting. You can see better, work cleaner, and keep neighbors much happier.
Fast Blasting!
Each grain achieves more work, which means you move the nozzle faster and on many projects finish the job much sooner!
Cleaner Surface!
Each blast stream can carry 4 times more Speedblast grains than coarse garnet. More grains, more cleaning power.
Use Less!
Low consumption means you buy less, load less, clean up less and consequently dispose of less.


text:
Predicting protein function has become increasingly demanding in the era of next generation sequencing technology. The task to assign a curator-reviewed function to every single sequence is impracticable. Bioinformatics tools, easy to use and able to provide automatic and reliable annotations at a genomic scale, are necessary and urgent. In this scenario, the Gene Ontology has provided the means to standardize the annotation classification with a structured vocabulary which can be easily exploited by computational methods.
Argot2 is a web-based function prediction tool able to annotate nucleic or protein sequences from small datasets up to entire genomes. It accepts as input a list of sequences in FASTA format, which are processed using BLAST and HMMER searches vs UniProKB and Pfam databases respectively; these sequences are then annotated with GO terms retrieved from the UniProtKB-GOA database and the terms are weighted using the e-values from BLAST and HMMER. The weighted GO terms are processed according to both their semantic similarity relations described by the Gene Ontology and their associated score. The algorithm is based on the original idea developed in a previous tool called Argot. The entire engine has been completely rewritten to improve both accuracy and computational efficiency, thus allowing for the annotation of complete genomes.
The revised algorithm has been already employed and successfully tested during in-house genome projects of grape and apple, and has proven to have a high precision and recall in all our benchmark conditions. It has also been successfully compared with Blast2GO, one of the methods most commonly employed for sequence annotation. The server is freely accessible at http://www.medcomp.medicina.unipd.it/Argot2 webcite.
Thanks to the advent of the Next Generation Sequencing technologies, we have assisted to an exponential increase in sequence data generation [1]. The task to assign a curator-reviewed function to every single sequence is unworkable, calling for efficient/effective methods to assign automatic annotation are necessary as a first analysis step to support working hypotheses and drive experimental validations of biological functions.
Computational approaches can be rather imprecise because functional inference is not as straightforward as one would expect, due to the unevenness of the classical paradigm "sequence-structure-function". Some authors suggest that for sequences sharing less than 30% of identity, the functional transfer may be highly inaccurate or completely wrong [2,3]: in particular Enzyme Classification (EC) numbers tend to be conserved only for proteins with sequence identity above 80%. Other authors report different figures [4,5] confirming the difficulty to agree on a unique view due to a certain unpredictability of biological systems.
In the category of sequence-based methods, the simple search for homologous sequences is considered a common practice for function prediction based on annotation transfer, and BLAST [6] can be considered a gold standard. If its classical pairwise alignment engine fails, the profile based PSI-BLAST [6] is able to identify relationship among distantly related proteins.
Another widely accepted approach relies on functional domains assignments. HMMER [7], which is based on Hidden Markov Models (HMM), is among the most known tools falling in this category. HMMER is mainly used to query the Pfam HMM models [8] and search for functional patterns and domains in the target sequences.
Recently, the Gene Ontology (GO) consortium [9] has revolutionized the way to access knowledge data and has rapidly become a standard de facto. The GO is organized in a hierarchical directed acyclic graph that greatly facilitates the mining of biological information by computational algorithms.
With the advent of GO and UniProtKB-GOA database (GOA) [10] of functionally annotated proteins, several algorithms have been developed to improve functional inference based on the plain use of BLAST [11]. Among these solutions, Blast2GO [12-14] can be considered one of the best platforms to assist the user in annotating sequences.
In this paper, we present Argot2 (Annotation Retrieval of Gene Ontology Terms), a tool designed for high-throughput annotation of large sequence data sets with high efficiency and precision. Argot2 is born for in-house needs to annotate predicted genes from large-scale sequencing projects; now it has a free and fully functional web interface and its engine has been completely revisited. It has been extensively tested during highly challenging endeavours as grape [15] and apple [16] genome annotations and it has been continuously refined from its early version, Argot [17], to reach a high flexibility and confidence in extracting fruitful knowledge from different sources of information. The web server version is computationally efficient, highly scalable, and it is able to address the different needs of basic and advanced users in annotating small sets of proteins up to entire genomes. Here we also report the assessment of Argot2 tested in four different configurations and in comparison with Blast2GO.
Algorithm description
Argot2 processes the GO annotations of the hits retrieved by BLAST and HMMER searches. A weighting scheme and a clustering approach are applied to select the most accurate GO terms for annotating the target proteins.
Argot2 takes a list of GO terms belonging to the GO graph G(V,E) as input and weights them according to the e-value score of the hits. Assuming that the set V is ordered, it is possible to establish a one-to-one correspondence between the ith GO term gi ∈ V used for the annotation, its weight wi and the e-value scores Si and Si' given by BLAST and HMMER. The weights are computed as follows:
As pfam2go [18] provides a minimal coverage of GO terms for each Pfam model, we extract from GOA the GO annotations of all proteins belonging to each Pfam entry to enrich these assignments. In Eq. 2 is the frequency of the GO term gi calculated over the total number P of proteins in the model and f(x) is a logistic curve introduced to reward highly frequent terms and to penalize those that are sparse and likely false positives.
All the possible paths starting from the input GO terms and leading to the root node are reconstructed and the GO nodes not included in any of these paths are discarded from the analysis, obtaining the so-called "GO-slim" (Figure 1-i).
Figure 1. Argot2 algorithm. i) Position of the retrieved nodes in the GO graph (black circles) with their weights (W). White circles connected by dashed lines are pruned GO terms that are not present in the final GO-slim. ii) Filtering steps based on Z-score and G-score (see the main text). The yellow big circles are the representatives of the corresponding groups having the highest Total Score (TS) and are used for the annotation. iii) The hexagons report the cumulative weights of the GO nodes i.e. W2 is obtained by the sum of its child nodes marked as black circles (WB and WC). Node 4 does not contribute to the cumulative score, as it is a reconstructed parent from node C. It inherits the weight of node C only (WC,4).
The remaining GO terms are grouped together in sets Grk ∈ ℘;(V) according to their semantic similarity [19]: the nodes that share a strong biological relationship form a unique informative group, and only the most specific and high scoring annotations are considered.
Given two generic GO terms gi, gj ∈ V, we use the Lin's formula [20] (Eq. 3) as a semantic similarity measure. This metric has been chosen since it gave the best results in clustering annotations with respect to other existing methods [17].
The Lin's formula is defined as:
In this formula, the function simres : V × V → ℜ defined as: represents the highest Information Content IC among the subsumers of the terms gi and gj. Using the notation gi ↦ gj to mean that a path from the term gi to the term gj exists, the set of the subsumers can be defined through the function S: V × V → ℘(V) as S(gi,gj) = {g ∈ V:g ↦ gi ^ g ↦ gj}.
The function IC : V → ℜ is the Information Content of the ith GO term calculated according to the Resnik formula [21] as:
where |{g:gi ↦ g}| indicates the total number of occurrences of GO terms descending from GO term i and |{g: g ∈ GOA}| is the total number of GO terms in the GOA database.
Three scores are then introduced to filter isolated GO terms and to rank the remaining ones. The first one, the Group Score GrS : N → ℜ, is the sum of the cumulative Internal Confidence InC of the nodes gj belonging to the kth group Grk, being N the set of the natural numbers:
The Internal Confidence InC : V → ℜ is a cumulative measure that takes into account the global cumulative weight distributions W: V → ℜ defined as , that is the sum of the weight w of a GO term g (Eq. 1 and Eq. 2) plus the weights of its children, and the sum of the cumulative weight of the root node (see Figure 1-iii):
The second score Z: V → ℜ, called Z-score, is calculated for each extracted GO term gi as follows:
where is the weight of the root node divided by the total number of the retrieved GO nodes, while σ is the standard deviation of all the weights.
If the Z-score and the Group Score are below a certain threshold, the corresponding GO terms are discarded. These filtering steps reward those paths, up to the root, that are statistically significant discarding the branches of the GO graph containing nodes with low weights (see in Figure 1-ii the discarded path and group).
After the filtering phases, the algorithm assigns the third score, the Total Score TS : V → ℜ, to each culled GO term gi, according to the following formula:
where Incnc: V → ℜ is the non-cumulative internal confidence, calculated as
Differently from the cumulative Internal Confidence InC defined by (Eq. 4), it estimates the local non-cumulative weight distribution, which considers only the weight of the term under analysis.
The function GrSnc : N → ℜ is the non-cumulative Group Score associated to the kth group Grk. It is calculated as the sum of the non cumulative Internal Confidence InCnc (Eq. 6) of the nodes belonging to that group:
The GO terms with TS above a chosen threshold are extracted and reported.
The score rewards those hits that are particularly significant and specific, thanks to the contribution of the Information Content (see yellow circles in Figure 1-ii).
The non cumulative measures InCnc and GrSnc have been introduced to guarantee that no biases are introduced due to the scores of child nodes.
Web server functionalities and features
Argot2 has been completely reengineered to speed up and improve the annotation process. The algorithm has undergone several adjustments to easily merge the GO annotations retrieved from different databases. UniProt [22] and Pfam are presently used as reference databases and queried using BLAST and HMMER respectively.
The server can be accessed in three ways addressing different needs from small to large scale function predictions (see Figure 2).
Figure 2. Activity diagram of the Argot2 web server. Activity diagram of the Argot2 web server showing the three types of access: "Interactive analysis" for up to 100 sequences, "Batch analysis" for more than 100 sequences and "Consensus analysis" based on provided weighted GO annotations (see the main text).
a) In the "interactive analysis" the user simply inputs up to 100 DNA/protein sequences in FASTA format. For every sequence, a table is shown containing: predicted annotations with scores, hyperlinks to external sources, lists of proteins contributing to the final annotation, and a graphical position map of the retrieved hits into the GO graph.
b) The "batch analysis" is addressed to researchers interested in the annotation of entire genomes. Since this process is highly demanding, due to the long computational time required by BLAST and HMMER, we ask users to perform BLAST and HMMER searches locally and then upload search results into Argot2.
c) The last access option is called "consensus analysis" as users may provide their own weighted GO terms for each protein; these annotations can be obtained by any other method or database, in addition or in alternative to the "default" BLAST and HMMER searches used by the web server. The outputs of the analyses of type b and c are Excel or Tab Separated Values (TSV) files listing the retrieved annotations along with specific metrics: Total Score, Information Content and Internal Confidence. Finally, predictions can be automatically clustered in functional classes by using the GOClass tool (Additional file 1) and viewed as pie-charts. The Argot2 algorithm steps are mainly based on the original idea published in [17]. Important changes have been applied to the procedure to filter potential false positive hits out during the evaluation of the predicted terms. The raw measure Total Score (TS) has also been redefined. The server is freely accessible at the URL in [23].
Additional file 1. GOClass algorithm details. Details of the GOClass algorithm used to cluster the GO terms, and more general views of the results obtained by Argot2.
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Argot2 assessment
Argot2 has been benchmarked in four different conditions to test how proteins (either kept or removed from the databank) influence the results, and which is the impact of domain based HMM searches. The four different configurations are indicated in the following as: a) BH_with, b) B_with, c) BH_without, d) B_without. The prefix "BH" means that Argot2 has been tested on BLAST and HMMER searches, whereas "B" only on BLAST searches. The suffix "with" means that the proteins of the test set are present in the databank and "without" means they have been eliminated. Argot2 has been also compared with Blast2GO.
The assessment of Argot2 was based on the guidelines of the "Critical Assessment of Function Annotations" (CAFA) experiment [24] (see Additional file 7). We tested over 4000 proteins with already available GO annotations in GOA, both from Eukaryota (Euk) and Prokaryota (Pro), randomly extracted from about 50000 sequences released for the CAFA challenge. In addition, the well annotated yeast genome, comprising 6187 annotated proteins, has also been used as a test set. The details and statistics of the test sets are available in Additional files 2, 3, 4, 5 and on our web site [25].
Additional file 2. Datasets statistics. Parameters used in the benchmarks and some statistics about the datasets.
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Additional file 3. Precision/Recall curves for the Eukaryota dataset. Precision/recall curves for Molecular Function (MF), Biological Process (BP) and Cellular Component (CC) calculated with methods m1 and m2 for Eukaryota test set.
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Additional file 4. Precision/Recall curves for the Prokaryota dataset. Precision/recall curves for Molecular Function (MF), Biological Process (BP) and Cellular Component (CC) calculated with methods m1 and m2 for Prokaryota test set.
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Additional file 5. Precision/Recall curves for the Yeast dataset. Precision/recall curves for Molecular Function (MF), Biological Process (BP) and Cellular Component (CC) calculated with methods m1 and m2 for Yeast test set.
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The evaluation has been carried out at a protein-centric level using the following criteria. Let N be a pool of unknown target proteins. For each given protein p, the GO terms predicted by each method are retrieved and ranked accordingly to the corresponding Total Score TSp (Eq. 5).
For a given threshold t applied to the Total Score TSp the four different configurations are assessed based on precision and recall, calculated for each protein p as:
The number of True Positives () is the size of the intersection between the sets of benchmark (true) and predicted GO terms with score TSp > t. The number of False Positives () is the size of the difference between the sets of predicted and true GO terms. The number of False Negatives () is the size of the difference between the sets of true and predicted GO terms. The denominators of (Eq. 7) and (Eq. 8) represent the total number of predicted terms and the number of true terms, respectively. If, for a given threshold t, a protein has not any annotated term, its precision is not calculated.
Assessment Method 1 (m1) with sliding threshold
We consider a set of threshold scores t ranging from 0 to the maximum observed score tmax. For each t, precision and recall are averaged across the N proteins of the pool, obtaining:
Each pair of values (1-PRt, RCt) represents a point of the precision/recall curve.
Assessment Method 2 (m2) with sliding threshold
We calculate precision and recall as in the case of m1 method, but all the GO terms retrieved by the different tools (predicted terms) and those originally annotated on the benchmark proteins (true terms) are first propagated to the root. Thus, all GO terms standing in the paths of the predicted/true terms up to the root are considered in the assessment. The idea is that a predicted GO term, though not exact, may share some of its parent nodes with some parent nodes of one true GO term. This term cannot be considered completely wrong but rather closely related and, consequently, its shared parent nodes are included in the evaluation. See Additional file 7 for details and extensive explanation of assessment m1 and m2.
Results and discussion
Precision/recall curves for Molecular Function (MF) and Biological Process (BP) have been calculated with method m1 and m2 for yeast (Figure 3), Eukaryota, and Prokaryota test sets (Additional file 3 and 4). The first outcome of our benchmarking provides evidence of the effectiveness of the combination of BLAST and HMMER weighted hits (BH vs. B curves shown in Figure 3) in recovering a large number of GO terms (high recall), without significantly affecting precision, and outperforming the use of BLAST alone.
Figure 3. Precision/recall curves of the yeast benchmark test. Precision/recall curves for Molecular Function (MF) and Biological Process (BP) calculated with method m1 and m2 (see the main text) for yeast test set. Recall and 1-precision of the tested algorithms are reported in y-axis and x-axis, respectively, for the two configurations "with" (keeping the benchmarked proteins in the databank) and "without" (removing them from the databank). See the main text for the abbreviations BH_with, B_with, BH_without, and B_without.
One potential bias in the assessment of all methods is that 84% and 99% of the proteins, in Euk and Pro test sets respectively (Additional file 2), are annotated without manual validation (Inferred from Electronic Annotation, IEA) and an over-estimation of tool performance may occur due to the use of predicted terms for functional inference [26]. To investigate the influence of this potential bias, the yeast proteome was used as benchmark, since a wealth of experimental data is available for this organism (over 84% of the proteins contain at least one non-IEA annotation. See Additional file 2). Though this is a challenging task involving 6187 sequences, the assessment gives an idea of what Argot2 is expected to do on a genome scale, namely to obtain a precise and thorough picture of molecular functions and biological processes of an entire organism. The general trends and the robustness shown in Pro and Euk test sets are confirmed (see Additional file 3, 4, and 6 from "a" to "h"). Nonetheless, a minor decrease in performance can be observed in yeast. This is due to the fact that yeast is mainly annotated with highly informative non-IEA GO terms, whose frequency in GOA databank is very low and consequently their retrieval may be a hard task. In particular it is possible to observe that the recall worsen, whereas the precision is only marginally affected proving that Argot2 is able to retrieve reliable and even low-frequent GO terms (compare for example the third column of Additional file 6 with the first two columns of the same figure, row by row).
Additional file 6. Precision/Recall curves for the Euk, Pro and Yeast datasets. Precision/recall curves for Molecular Function (MF) and Biological Process (BP) calculated with methods m1 and m2 for Euk, Pro and Yeast test sets.
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Additional file 7. CAFA guidelines explanation. Document that explains m1 and m2 methods using a simple example.
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This trend is confirmed when target proteins are removed from the databanks used to train Argot2 (see curves suffixed by "with" vs. those suffixed by "without" in Figure 3). This issue is not present in Pro and Euk test sets, which mainly include highly frequent IEA GO terms. As expected, results of Pro and Euk test sets get slightly worse (see Additional file 3 and 4), but yeast is more affected and Argot2 finds more difficulties in extracting the right GO terms (see Figure 3, column "m1"). Nevertheless, method m2 reveals that, in these critical situations, Argot2 tends to be conservative rather than inaccurate, i.e. to show a lower recall but still a good precision (see Figure 3: "a" vs. "c", "b" vs. "d", "BH_without" and "B_without"). In conclusion, the lower performance is due to shallowness rather than inaccuracy. This means that most of the predicted nodes, though approximate, fall into the path of the correct annotations.
Finally, some interesting conclusions can be drawn in the "one-to-one" comparison with Blast2GO using the B_with Argot2 version that exploits the same BLAST data of Blast2GO. According to benchmark "m2", the recall is generally higher for Argot2 whereas the precision is comparable, to some extent, between the two tools. However, Argot2 is more effective in retrieving the exact original annotations, as evidenced by the use of assessment method m1 (see "m1" column in Figure 3 and "m1" rows in Additional file 6). The irregular contour trend of Blast2GO may be due to the sliding "Annotation Cut-off" parameter, which does not seem to be a well discriminating score. Fine tuning may be required, even though the default value suggested for the parameter "Annotation Cut-off", i.e. 55, gives the best trade-off between precision and recall. Moreover, Argot2 is fairly more computationally efficient compared to Blast2GO. Starting from BLAST and HMMER results, which remain the limiting steps of the process, Argot2 takes only few hours to annotate an entire genome.
Argot has been revisited to increase both accuracy and precision, thanks to an improved weighting scheme and the introduction of Pfam models. The server automatically downloads new releases of the used databanks UniProtKB-GOA, UniProt, Gene Ontology, and Pfam on a monthly basis to give end users an updated access to the tool. Presently, in our testing conditions Argot2 performs reasonably well in terms of both precision and recall, showing that TS score can effectively discriminate among false and true positives. The main rationale has been to create a tool able to favour the precision with respect to the recall. This is critical when annotating very large genome data sets, since reducing the false positives rate is definitely desirable. This can prevent biased information from impacting negatively on post-genome studies and statistics. In addition, we plan to associate a p-value to the raw score TS and to add new sources of information, trying to give an answer to non-trivial cases that lie in the twilight zone beyond similarity based evidences. In future releases we could explore other metrics, for example to assess different semantic similarity measures and to compare their performances with Lin's formula currently used by Argot2 (see [27]).
List of abbreviations used
All abbreviations in the text excluded from the following list are specific of this paper and have been defined in the main text.
BLAST: Basic Local Alignment Search Tool; GO: Gene Ontology; GOA: Gene Ontology Annotation; EC: Enzyme Classification; PSI-BLAST: Position-Specific Iterative Basic Local Alignment Search Tool; HMM: Hidden Markov Model; TSV: Tab Separated Values; URL: Uniform Resource Locator; CAFA: Critical Assessment of Function Annotations; TP: True Positive; FP: False Positive; FN: False Negative; MF: Molecular Function; BP: Biological Process; IEA: Inferred by Electronic Annotation.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
Critical revision of the manuscript for important intellectual input: ST, RV, PF, BDC. Technical and material support: MF, EC, EL, AF. Study supervision: PF and ST. Study concept: ST, MF, BDC, PF. Architectural design: MF, ST. Software development: MF, PF, AP and EC. Drafting of the manuscript: ST, BDC and PF. All authors read and approved the final manuscript.
We thank Luca Bianco for critical reading of the paper and for fruitful suggestions.
This article has been published as part of BMC Bioinformatics Volume 13 Supplement 4, 2012: Italian Society of Bioinformatics (BITS): Annual Meeting 2011. The full contents of the supplement are available online at http://www.biomedcentral.com/1471-2105/13/S4.
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USA Network upfront: old characters, and a few new ones - AUDIO
All that's well and good -- be ready for more product placement and ad pods that other networks have recently adopted -- but the best part about an upfront presentation are the stars that the network drags out to schmooze and booze with those advertisers. And USA brought the big guns, including Tony Shalhoub from Monk, Debra Messing from The Starter Wife, Jeffrey Donovan and Bruce Campbell from Burn Notice, Dulé Hill, James Roday, and Corbin Bernsen from Psych, Kathryn Erbe and Chris Noth from Law & Order: Criminal Intent, the WWE's Triple H and Shawn Michaels, and Mary McCormack from the network's new show In Plain Sight. I got to speak to a few of them; audio of those interviews is after the jump.
Gallery: USA Network Upfront 2008
Shalhoub and Messing were the only stars to come to the podium, as they introduced NBCU's cable division president, Bonnie Hammer. Unlike other upfronts, shtick was kept to a minimum, even though Shalhoub did take a second to wipe off his and Messing's wine glasses a la Shalhoub's character of Adrian Monk. Hammer crowed about USA's ratings, saying that they even outpaced The CW's ratings by a double-digit margin.
But most of Hammer's and the other executives' presentations centered around the characters the network has developed on its original series -- and one not-so-original show. I found it odd how, in their pre-recorded montages, the network decided to throw in clips from the House reruns they air on Friday nights along with clips from their original shows and the WWE. It seemed out of place, not because House doesn't adhere to the "characters welcome" theme, but because... well, because it's not their show. But whatever gets the advertisers to cough up some money, right?
It was also odd that they only announced one new show at the upfront, In Plain Sight, about an FBI agent who can't tell anyone she knows about her job, because she works in the witness protection program. None of the new shows Bob posted about earlier this morning were even mentioned. Maybe they're not ready to go yet.
Anyway, I got to sit down (or in one case, stand) with a few of the stars that showed up...
First up was Tony Shalhoub. Since I've interviewed Monk executive producer Andy Breckman before, I pulled both of them back to the lounge and asked them about the show's upcoming seventh season. God bless Andy; while every guy in the room was wearing a dark suit and looking very Hollywood, Andy wore the same rumpled outfit he wears to the Monk writer's room and just about everywhere else: a corduroy blazer, wrinkled khakis, and a white floppy baseball cap. Let's just say it was easy to find him in the crowd.
Shalhoub thinks that his character and the others in the show are being explored more deeply as time goes along. During the show's sixth season, we saw Adrian Monk's rage and anger come out a little more, and "I think we're going to continue to see that come out more. It's less of the tentative character... not that he turns into a bad ass, it's just that channel inside of him helps him access his rage and open up more. I have a feeling that's going to be a new color for the show." He also humbly said that the show's other characters have "blossomed" over the last year.
Tony Shalhoub and Andy Breckman on Monk's seventh season (9:06)
The upcoming season will contain Monk's 100th episode; it'll be partially a clip show, where Adrian Monk will work his 100th case for the San Francisco PD, while a reporter writes a profile about him. The reporter will meet "old friends," as Breckman put it, who will reflect on Monk and his past cases. "At first I thought, hey it'll be a breeze but I think it's going to be a challenge," said Breckman. Shalhoub chimed in by joking that "we're hoping it's really really expensive, too."
Shalhoub is signed on for the seventh and a possible eighth season. And even though Breckman originally envisioned Monk going eight years, he can definitely see it going more. But he does have an ending in mind: "I know how the series will end. And I'm not telling my friend Tony. I just don't want to inform his character by knowing where he's going."
Next is Dulé Hill of Psych. Most of my questions concentrated on going from a supporting role on The West Wing to sharing the sharing load with Roday on his current show. But I also asked him what it's like on the set and what it's like to work with Corbin Bernsen.
Dulé Hill on going from West Wing to Psych (5:28)
When I asked him about Psych reruns being shown (with Monk) on NBC starting in April, he joked that "I can't get out of NBC. When I got out of The West Wing, I didn't know how the hierarchy really works, but when I figured it out, I said 'You mean Jeff Zucker is still my boss?'" When I asked him what he's got coming up, he said "I'm going to Jamaica" like a man who definitely was looking forward to his vacation.
I wanted to speak to Bruce Campbell of Burn Notice and ask him a bunch of Evil Dead questions, but, alas, I didn't get a chance to pull him aside. I did sit down next to the show's star, Jeffrey Donovan, while he was speaking to another reporter. When the reporter slowed down, I jumped in with a question that is near and dear to my heart, since I didn't watch the first season of the show:
Jeffrey Donovan on why new viewers will enjoy Burn Notice (1:49)
Last up was Debra Messing. When she came over to speak to another blogger, I overheard her telling the PR rep that "I thought I was supposed to type!" I had guessed she heard the word "blog" or "blogger" and thought the reporter was safely ensconced at home in front of her computer. Ah, she doesn't realize that we actually get press passes and everything now. Anyway, I asked her about that, right after she admired my tiny voice recorder as I changed its battery:
Debra Messing on coming back to series TV with The Starter Wife (6:37)
After one question, I was getting a "wrap it up" signal from one of Messing's friends / handlers because she needed to leave, but Debra was nice enough to keep going. Because The Starter Wife was supposed to be a one-time miniseries, it's technically going into its first full season as a regular series. After eight years on Will & Grace, she was "very reluctant" to go back to series television.
"It was something I was very much against when I wrapped up Will & Grace," she said. "I had plans to do theater and take a break from playing one character for any extended period of time, because I actually don't think that we as actors are buoilt to do that, fundamentally. But (the script) was sent to me, and I felt the writing was really special, and I'd have to be pretty stupid not to acknowledge that."
You can find the current list of USA's series here, including some of their new shows and shows like Dr. Steve-O, whose star (thankfully) wasn't at the upfront.


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Proteins are major targets of Pharmaceuticals, and are themselves increasingly used as therapeuticals. However both basic research and the pharmaceutical industry depends on availability of purified proteins that are often difficult to isolate from native sources. In this lecture course, students will learn basic and advanced theoretical background in expression and purification of recombinant proteins. It will cover a variety of expression systems, including prokaryotic and eukaryotic cells. The course will also address traditional and new methods in recombinant protein purification. Furthermore, students will be introduced to some downstream applications such as crystallization screens and biochemical/biophysical studies. Student will choose a term project for oral and written presentation.


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Brilliancy and splendour
Posted: November 06, 2009|
NOTTINGHAM'S contemporary craft makers' market, Lustre, combines culture, aesthetics and retail in one place.
From the hundreds in the UK who apply to exhibit at Lustre, just 55 get to take part. A panel of experts goes through the selections carefully before making the final decision. It keeps quality high and the variety interesting for the visitors.
This choosiness is also why it's become one of the renowned events of its kind outside London, and must for anyone who wants to find the best original work in jewellery, textiles, ceramics, glass, wood, leather, furniture and metal.
Taking place at Lakeside, the University of Nottingham's public arts centre, it's now in its tenth year.
Individually and collectively the participants have to live up to the definition of the word lustre – that is, brilliancy and splendour. The event promises: 'Beautiful things for you and your home.'
Lesley Beale, Lakeside's craft co-ordinator, says: "We have some really exciting first time Lustre exhibitors this year, whose work I can't wait to see.
I really get a buzz on the Friday when the first makers start to arrive and set up and then a sense of anticipation just before the doors open to the public.
"Working with the Young Meteors – graduates from Nottingham Trent University, Loughborough, Leicester and Derby – is very rewarding and great fun, the enthusiasm they have is infectious."
There are, as usual, a wide range of must-see 'makers' in 2009, including figurative sculptors Abbott and Ellwood, dynamic textile maker Craig Fellows and his chic silk scarves, and jewellery makers John and Jane Moore return with their innovative and highly wearable work.
Also present will be the well known Yungi range, which includes knitted throws, cushions and scarves, made from 100% pure lambs wool, giving the products an irresistibly cosy and soft feel.
Debut 'maker' Simon Mount, who works from his studio in Worksop. He runs Doistrinta, a furniture and product design company, creating furniture, lighting, fabrics and smaller accessories, using sustainable materials.
Simon says: "I visited Lustre about five years ago and have been visiting ever since. I am really looking forward to participating as an exhibitor this year!
"It's great to be part of an event in our own back yard. The quality of exhibitors is as good as any of the high profile London shows so it's a really exciting opportunity.
"For national and local makers, I think visitors to Lustre appear to have a real passion for craft, there always seems to be a buzz when I visit."
Shona Powell, director at Lakeside, believes the fair is growing in popularity each year.
She said: "Over 4,000 people attended last year, and in 2009 we promise another opportunity to discover a wealth of original design from talented makers across the United Kingdom. We firmly believe that you'll find something that you like, need, or would really love to give."


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A Taste for Water
A month ago I wrote about beverage choices in Nicaragua (http://foodsobriety.net/?p=1076) today I am revisiting that topic with a focus on water. Whenever I have volunteered in health clinics in Latin America the issue of dehydration comes up with surprising frequency. Of all the frustrating, and difficult health conditions one sees in these clinics I never anticipated that dehydration could rank so highly as a major concern. Dehydration worsens dozens of common health problems and was almost single handily responsible … Continue reading


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The following property sales were recorded in the Jefferson County clerks office Jan. 28, 2013:
City of Watertown: 222 S. Meadow St., Joseph A. Chirico, Black River, sold to Derrick J. Kehoe, Watertown $60,000
Town of Cape Vincent: Road from Clayton to Cape Vincent, D. Christopher Pitman, Skaneateles; Eric J. Pitman, Skaneateles; and Monica S. Pitman, Marcellus, devisees under will of Ernest L. Pitman, sold to Christopher Malinowski and Patricia Chapin, both of Columbia, Md. $160,000
Town of Orleans: 1.029 acres, Smith Road, Rene S. Jones, Norfolk, sold to Robert G. Switzer and Carla L. Switzer, LaFargeville $27,500
The following property sales were recorded in the Jefferson County clerks office Jan. 29, 2013:
Town of Brownville: 1.665 acres, intersection of state Route 180 and state Route 12E, Ronald J. Jones, Manchester, N.H., and Helen H. Halbmaier, Lebanon, Maine, co-executors, will of Richard A. Huff, late of Jefferson County, sold to Michael Huot, Dexter $42,000
City of Watertown: Mullin Street, Kathleen L. Lupia, Lack Placid, sold to Scott Wheeler and Kathleen Wheeler, Watertown $117,000
The following property sale was recorded in the Jefferson County clerks office Jan. 30, 2013:
Village of Philadelphia: 0.25 acre, road from village of Philadelphia to Antwerp, Donald L. Myers, Mexico, sold to Gregory L. Delles, Philadelphia $68,000
The following property sales were recorded in the Jefferson County clerks office Jan. 31, 2013:
Town of Hounsfield: Evans Road, Charles S. Rhoden, Dexter, sold to David I. Strouse and Tissa L. Strouse, Fort Drum $288,000
Town of Theresa: 54.71 acres, state Route 37, Terri L. Brown, Theresa, sold to Kelli Jo LaClair, Fishers Landing $167,000
Town of Pamelia: 0.769 acre, state Route 37, Gerald R. Perry Jr., Fort Walton Beach, Fla., and Lisa A. Perry, Dexter, sold to Brian C. Larose and Jessica M. Knapp, both of Watertown $93,000
Town of Lorraine: 11 acres, Lot 27, County Route 189, Moose River Land Company LLC, Westernville, sold to Bryan Thomas, Minot, Maine $25,000
Village of West Carthage: Two parcels, each 0.20 acre, no addresses given, Jeffery S. Carter, Eden, Vt., and Timothy J. Carter, Hinton, Va., sold to Daniel D. Bossuot, Felts Mills $100,000
The following property sales were recorded in the Jefferson County clerks office Feb. 1, 2013:
Town of Cape Vincent: 82.19 acres, Carleton Island, Clifford S. Robert, Melville, executor, will of Charles W. Schwing, late of Matinecock, a member of Electrical Wholesale Distribution Co. LLC, and Peter S. Schwing, Huntington, as member/manager of Electrical Wholesale Distribution Co. LLC, and as individual partner of Seal Realty Co., sold to Michael J. Comerford and Eileen T. Comerford, Bonita Springs, Fla. $200,000
Town of Watertown: Two parcels, 0.59 acre, 0.05 acre, County Route 68, William W. Conde III, Watertown, sold to William G. Crane Jr., Danville, Ky. $240,000
Town of Alexandria: 1.9 acres, Fairyland Island, Estrellita LLC, Lebanon, Pa., sold to Edward P. Denigan III and Vida J. Denigan, West Chester, Pa. $925,000
Village of Clayton: 0.31 acre, Hugunin Street, William F. Ramseier, Clayton, and Joey Lynn M. Ramseier, LaFargeville, sold to Daniel N. Frank and Karen L. Frank, Windham $215,000
City of Watertown: 728 Morrison St. (foreclosure), Cynthia Michelle McKenzie, Watertown, referee, Olivia Russell, sold to Midfirst Bank, Oklahoma City, Okla. $53,000
Town of Cape Vincent: 76.85 acres, Stoney Point Road, Melanie Curley, Cape Vincent, sold to David Bourquin and Jeanine Bourquin, Chaumont $90,000
Village of Carthage: Parham Street, Roberto Nunez and Peggy S. Nunez, Carthage, sold to Keith A. Rondo and Madeleine C. Rondo, Carthage $122,000
Village of Philadelphia: Church Street, George J. DeVita and Sylvia A. DeVita, Evans Mills, sold to Joseph Z. Marion, Evans Mills $134,500
Town of Brownville: Two parcels, 0.172 acre, County Route 59; building lot, south shore of Sherwins Bay, Francis H. Prevost and Rosalie T. Prevost, Watertown, sold to Jeremy J. Prevost, Watertown $125,000
@datebook city label underlined:ST. LAWRENCE COUNTY
The following property sales were recorded in the St. Lawrence County clerks office Jan. 9, 2013:
Town of Oswegatchie: 22.785 acres more or less, bounded by state Route 37, Ali M. Gharagoz and Chihara Kinoshita, Ogdensburg, sold to Xiulan Jiang, Qingdao, China $350,000
Village of Massena: Unknown acres, in Lot 18, bounded by Walnut Avenue, Ana Martinez, Massena, sold to Stefan Dufranse, Massena $60,000
Town of Hermon: 26.45 acres more or less, bounded by County Route 3, Wayne A. and Mary E. Knight, Hammond, sold to David J. Powelczyk and Frances C. Zarb, Hammond $36,000
Town of Oswegatchie: 1 acre more or less, in Lot 18, bounded by Camp Road, Kathryn A. Maxwell, Ontario, Canada, sold to Mark H. Youngs, Ogdensburg $25,300
The following property sales were recorded in the St. Lawrence County clerks office Jan. 10, 2013:
Town of Fowler: 4.61 acres more or less, bounded by Route 812, Cory D. and Amanda L. Hance, Fowler, sold to Patrick Brown and Jennie Hutton, Fowler $87,500
Town of Gouverneur: 1/2 of an acre more or less, bounded by Mud Creek, Frederic J. Delosh, Gouverneur, sold to Marco A. Curcio, Gouverneur and Jessica L. Nowak, Gouverneur $25,000
Village of Massena: Unknown acres, in Lot 2 of Block 9, bounded by Bridges Avenue, Rebecca L. Pomainville, Massena, sold to Joel T. and Carolyn J. Griggs, Massena $124,550
Town of Madrid: 0.81 of an acre more or less, bounded by Route 31, Cynthia I. Clegg, Madrid, sold to Reggie and Vikki Burcume-Hooper, Canton $118,600
Town of Hammond: Hamlet of Chippewa Bay, 0.26 of an acre more or less, bounded by Church Street and Route 6, Anthony M. Menkel III, Williamstown, Mass., sold to Smoothrock LLC, Hammond $27,000
The following property sales were recorded in the St. Lawrence County clerks office Jan. 11, 2013:
Town of Canton: 4.56 acres more or less, in Mile Square 4 of Range 4, bounded by Route 27, Barbara Peters, Canton, sold to James and Shelly Sanderson, Canton $100,000
Town of Canton: Hamlet of Morley, 0.539 of an acre more or less, bounded by County Road 345, Dale R. and Colleen M. Grant, Canton, sold to Dane G. Ames, Canton $44,000
Town of Stockholm: 0.78 of an acre more or less, bounded by East Part Road, Scott J. Tassie, Winthrop, sold to Lisa Mitchell, Winthrop $65,000
Village of Potsdam: Unknown acres, in Lot 8, bounded by Circle Drive, Susan J. Sewall, Massena, and David T. Van Ness, Malone, sold to Nathan W. Konte, Potsdam $117,500
Village of Massena: Unknown acres, in Lot 6 in Joy Tract, Michael D. and Cynthia A. Mayette, Massena, sold to Gary M. Hamilton, Bay City, Mich. $80,000
The following property sales were recorded in the St. Lawrence County clerks office Jan. 14, 2013:
Town of Gouverneur: 2 parcels, unknown acres, bounded by state Route 58, Mary Judith Redmond, Gouverneur, sold to Rusty J. Hartle, Gouverneur $50,000
Town of Massena: Unknown acres, in Lot 64, bounded by Middlebury Avenue (foreclosure), Nicholas E. Fodor (referee in action), Ronald R. and Diana Sharlow et al, no addresses given, sold to Abby L. Griffiths, Massena $48,500
The following property sales were recorded in the St. Lawrence County clerks office Jan. 15, 2013:
Village of Canton: 0.12 of an acre more or less, bounded by Greens building and Axtells building, Patrick Hackett Hardware Co., no address given, sold to Gary Cohen, no address given $57,500
City of Ogdensburg: Unknown acres, in Lots 7 and 8 of Block 21, bounded by South Street, John M. Reed, Ogdensburg, and John H. Reed, Ogdensburg, sold to Joey S. Reed, Ogdensburg $80,000
Town of Parishville: Unknown parcels, unknown acres, in Mile Square 13 of Township 14, Joanne Hair, Ogdensburg, Faye LaValley, Clifton Park, Donna Cruz, Rochester and Diane Cary-Dingle, Rochester, sold to Diane Cary-Dingle, Rochester $75,000
The following property sales were recorded in the St. Lawrence County clerks office Jan. 16, 2013:
Town of Fine: 2 parcels, 108.04 acres more or less, and 76.38 acres more or less, both in Great Tract 3 of Township 12, Randy Clark, Star Lake, sold to David P. Northrup Jr. and Terra J. Northup, Oswegatchie $163,000
Town of Lisbon: 0.305 of an acre more or less, bounded by Route 10, Helen Paxton, Lexington, S.C., sold to Jonathan Adams, Lisbon $50,000
City of Ogdensburg: 164 51/100 acres more or less, in Block 31, bounded by Knox and Jay streets, Christopher J. and Erin E. Woods, Ogdensburg, sold to Christopher R. Frary, Ogdensburg $100,000
Village of Norwood: Town of Potsdam, unknown acres, bounded by Pine Street, Leann Sharp, Norwood, sold to Erin J. Woodley, Canton $25,000
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Mountain Guiding | Summer
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Book a single day or multi-day guided trip. We will devise a trip based on your experience, fitness and aspirations.
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- Longer daylight hours give time for training, and attempting longer routes
No fixed departure dates
You can choose the start date of your summer guiding trip to fit with your travel plans.


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« Sept. 23 Sept. 25 » Saturday, September 24, 2011
Chiefs allow three power-play goals in season-opening loss
Sept. 24, 2011 in Sports The Spokane Chiefs showed that they were going to work hard. Now they just have to work a little smarter.
Blanchette: Not the destiny Eagles had in mind
Sept. 24, 2011 in Sports In front of 10,422 witnesses done medium- well, Eastern Washington returned to the red Saturday in an atmosphere charged with possibility as anxious as it was eager. Soon we discovered …
Eagles fall to 0-4 as Montana State makes key plays
Sept. 24, 2011 in Sports Talk to the coaches and players on Eastern Washington's still-winless football team, and, to a man, they'll tell you that things don't feel that far off. 1
Vandals' offense sputters in defeat to Fresno State
Sept. 24, 2011 in Sports By now, it's more than an occasional occurrence. The Idaho offense slips into hibernation mode, the defense grows frustrated and weary, and the Vandals' opponent pounces.
Whitworth football team lets another slip by
Sept. 24, 2011 in Sports Whitworth added to its growing list of losing winnable football games, coming up short in the trenches and falling to Menlo 24-17 in front of 1,405 Saturday at the Pine …
Police kill shooter near Issaquah high school
Sept. 24, 2011 in Region ISSAQUAH, Wash. (AP) — Police in Washington state say they have fatally shot an armed man who repeatedly opened fire near a high school where students were attending games. 9
Q & A with WSU athletic director Bill Moos
Sept. 24, 2011 in Sports We sat down with WSU athletic director Bill Moos in his office this week to talk about the changes that have occurred at WSU and those on the drawing table, …
UW wins, off to best start in six years
Sept. 24, 2011 in Sports Keith Price threw for 292 yards and three touchdowns and Chris Polk added a touchdown on the ground as Washington knocked off California 31-23 to get off to their best …
Hernandez injured in Mariners' loss
Sept. 24, 2011 in Sports Seattle ace Felix Hernandez was forced out of the game when he took a line drive off his right forearm during the Rangers' six-run fourth inning Saturday, and Texas used … 1
Highway 20 crash kills motorcyclist
Sept. 24, 2011 in News A motorcyclist died in a crash this morning on Highway 20 four miles south of Cusick. 2
Tribe, county battle over hunting rights
Sept. 24, 2011 in Idaho The Benewah County prosecutor was incorrect to say the Coeur d'Alene Tribe in North Idaho does not have the right to hunt or fish on reservation land owned by non-tribal … 2
Quincy shooting leaves one dead
Sept. 24, 2011 in News A shooting last night in Quincy has left one man dead. Authorities say the shooter is still at large. 1
NASA: 6-ton satellite hits Earth; location unknown
Sept. 24, 2011 WASHINGTON (AP) — NASA's dead 6-ton satellite plunged to Earth early Saturday, but more than eight hours later, U.S. space officials didn't know just where it hit. They thought the …
Tight drug supplies endanger patients
Sept. 24, 2011 in Nation/World on Page A1 TRENTON, N.J. – A drug for dangerously high blood pressure, normally priced at $25.90 per dose, offered to hospitals for $1,200. Fifteen deaths in 15 months blamed on shortages of … 4
Obama lets states opt out of No Child Left Behind
Sept. 24, 2011 in Nation/World on Page A1 WASHINGTON – Nearly everyone agrees the fix needs fixing. The No Child Left Behind law that was supposed to improve American education has left schools grumbling at being labeled "failures," … 7
Gunshot killed hunter during grizzly's attack
Sept. 24, 2011 in City on Page A1 A hunter who died during a grizzly bear attack was killed by a single gunshot wound to the chest, the Montana State Crime Lab medical examiner announced Friday. Steve Stevenson, … 10
Getting a nose count
Sept. 24, 2011 in News on Page A1 Next summer, grizzly bears will follow their noses to census sites. Enticed by the smell of fermented cow blood and fish guts, they'll crawl through corrals of barbed wire to … 2
Satellite hangs in space a little longer
Sept. 24, 2011 in Nation/World on Page A2 CAPE CANAVERAL, Fla. – A 6-ton NASA satellite on a collision course with Earth clung to space Friday, apparently flipping position in its ever-lower orbit and stalling its death plunge. …
Sept. 24, 2011 in Nation/World on Page A2 Friday's Washington Daily Game: 6-5-9 Friday's Washington Keno: 3-17-28-33- 38-40-41-42-45-48-49-51-52-60-64- 65-68-69-76-79
Senate blocks House budget bill as deadline looms
Sept. 24, 2011 in Nation/World on Page A3 WASHINGTON – Just a week away from a possible government shutdown, lawmakers boxed themselves into a new budget impasse Friday. With Congress' approval ratings already at an all-time low, a …
Saleh returns to tense Yemen
Sept. 24, 2011 in Nation/World on Page A3 SANAA, Yemen – Security forces opened fire on anti-government demonstrators in downtown Sanaa early today, just hours after President Ali Abdullah Saleh surprised his supporters and shocked his opponents by …
In brief: $119,000 added to Anthony's bill
Sept. 24, 2011 in Nation/World on Page A3 ORLANDO, Fla. – A Florida judge Friday increased the reimbursement costs Casey Anthony must pay to investigators for searching for her missing 2-year-old daughter three years ago. Judge Belvin Perry …
Idaho will seek waiver, Luna says
Sept. 24, 2011 in City on Page A4 Idaho will be among the first states to apply for a waiver from the federal government to skirt provisions of the No Child Left Behind education law, according to the … 1
Fatal grizzly attacks trigger policy review
Sept. 24, 2011 in Idaho on Page A5 Yellowstone National Park officials say they'll review park policies following two fatal grizzly attacks this summer. One incident involved a solo hiker, John Wallace, 59, of Michigan, who died Aug. …


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by Mike Arnold As the most widely used drug in BB?ing, testosterone?s rise to dominance did not take place by chance. For over a generation it has been proving itself in the real-world; taking size and strength to never before seen levels in bodybuilders and strength athletes alike. However, it was not until recently that […]
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text: F**k! Watch Danny Dyer try virtual reality Palmer-Tomkinson arrested at Heathrow See Palmer-Tomkinson talk drugs on Jeremy Kyle Barrymore for Jeremy Kyle celeb specials The Jump: Riskiest reality show ever? The Jump: Sam Jones out with injury Tara Palmer-Tomkinson quits The Jump Steve Redgrave, Sinitta for C4's The Jump 8 classic I'm a Celebrity spats Tara Palmer-Tomkinson completes rehab Palmer-Tomkinson 'arrested' at airport Is Helen Flanagan most annoying ever? Tara Palmer-Tomkinson 'back in rehab' Digital Spy's Pictures of the Week Palmer-Tomkinson worse for wear - pic Tara Palmer-Tomkinson unveils debut song Tara Palmer-Tomkinson for Dancing on Ice? Beckhams deny royal wedding frustration Who is the ultimate 'I'm a Celeb' star? Tara Palmer-Tomkinson denies drug use Tara Palmer-Tomkinson sparks health fears Kerry Katona mocks Tara Palmer-Tomkinson nose Lauren Goodger explains nose surgery Tara Palmer-Tomkinson 'getting new nose' Palmer-Tomkinson 'flirts' with Harry Styles? Palmer-Tomkinson confirms tell-all book Palmer-Tomkinson angered by 'Enders Palmer-Tomkinson: 'I frighten men away' Goody turns to holistic treatment Tara PT: UK rehab system "sucks" McLean blasts Lloyd, Palmer-Tomkinson Kidd takes part in showjumping contest Tara PT: 'My album sounds like Dido' Tara PT defends Knightley over weight Tara PT wants public to have faith in her Tara Palmer-Tomkinson reveals dog crush Living confirms 'Underdog' series two Palmer-Tomkinson 'drunk' at charity bash Tara: 'I may have child with gay friend'


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Often you'll find recipes for this classic Hungarian dish swimming in a heavy cream sauce. By adding just a little more sherry wine and boiling it down until until the sauce starts to thicken, a dollop of sour cream is all you need to make a healthier version that is just as luscious. While this dish may seem too fancy to be fast and easy, trust me, it is.
Get school tips, recipes, worksheets, and more
Try These Tips From The Meal Makeover MomsWhen my children were younger, we played the "Three Pennies Game" at dinnertime. Each of us got three pennies, and the object was to get rid of your pennies before the meal was over.


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MetalStorm: Online
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Release Date: May 12, 2011
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Game Details
Published by: Z2Live
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Genre: Online Flight
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United States: May 12, 2011
UK: May 12, 2011
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Also known as: MetalStorm
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PNP beefs up drive vs child abuse-A A +A
Sunday, March 16, 2014
THE Philippine National Police (PNP) will spend 10,000 pounds or roughly P750,000 to gain access to a global database of child abusers as part of its campaign against those who use minors in pornography and other Internet-driven crimes.
Anti-Cybercrime Group head Police Superintendent Gilbert Sosa said the amount, which was recently approved by PNP Chief Director General Alan Purisima, is an initial contribution to the Virtual Global Task Force (VGT), an association of law enforcement agencies worldwide.
"May database ng sex offenders worldwide ang VGT. 'Yung may mga kaso na ng child abuse materials, binabantayan na sila 'pag nag-travel. I-inspect agad ang computers and gadgets nila every time lalabas sila ng bansa. They have software and hardware to help the investigation," said Sosa.
VGT system is not accessible to non-members.
Sosa said they are focused on addressing the worsening problem of production and distribution of abuse materials.
"For every cybercrime committed, there is a financial loss behind it. In every child abuse material produced, there is a minor that has been corrupted," he said.
The PNP-ACG continues to train its 120 personnel and spread awareness to the public, especially to the parents who are in direct contact with their children.
"All of us will benefit if we can bring down cybercrime if not totally eliminate it," Sosa said. (Third Anne Peralta/Sunnex)
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