text:
- The Heineken-owned beer brand Kronenbourg 1664 has appointed Ogilvy & Mather to its £5 million UK advertising account.
Read more: http://bit.ly/Ix7CCK
- EDF Energy has appointed AKQA as its lead digital advertising agency.
Read more: http://bit.ly/JgKoOI
- Carlsberg, the brewing group, has appointed LBi to handle its global digital account.
Read more: http://bit.ly/IYCWIH
- AkzoNobel has appointed Glue Isobar to handle its digital creative account across its portfolio of DIY products.
Read more: http://bit.ly/KsQF8N
- Bombay Sapphire, the Bacardi Group gin brand, has added Gravity Road to its global roster to lead its content partnerships.
Read more: http://bit.ly/Ip76nF
- VCCP has been handed the £25m advertising account for Muller Dairy, taking over from TBWA\London, which resigned from the account in December last year.
Read more: http://bit.ly/IG6vT0
- Liam Gallagher's fashion brand Pretty Green has hired the creative agency Holler to handle its advertising.
Read more: http://bit.ly/IJl1tz
- London Business School has appointed The Communications Agency to handle its advertising and customer communications activity.
Read more: http://bit.ly/IMcvn3
- Orbis, the international fund management company, has appointed the start-up agency The Corner to handle its £7 million advertising activity.
Read more: http://bit.ly/KsRIWg
Tags: Heineken, Kronenbourg 1664, Ogilvy & Mather, EDF Energy, AKQA, Carlsberg, LBi, AkzoNobel, Glue Isobar, DIY, Bombay Sapphire, Bacardi Group, Gravity Road, VCCP, Muller Dairy, TBWA\London, Pretty Green, Holler, Orbis, London Business School, The Commun
Category: Account Moves


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Michael Clay "just getting ready for the Huskies" after injury against WSU
Sometimes you back into a question, or ask it vaguely, or try some other strategy.
With Michael Clay, I figured I'd be up front.
There's a conflict here, with many of your fans wanting to know how you're doing after not playing in the second half last week against Washington State due to injury, and your coaches not wanting you to say anything. So, what could he tell us today after practice?
"Just getting ready for the Huskies," Clay said with a smile and a shrug. "Take it from there day by day."
For the second straight practice, Clay today walked out of Autzen Stadium with the same gear as his teammates. He suffered what looked like a right leg injury on a sack late in the first half against WSU, and was in street clothes for the second half.
"Something didn't feel right," Clay said today, of an injury that's tough to detect on film, until he motioned for a replacement and began favoring his right leg a few steps after the sack Saturday night. Whatever it was, it's caused him to "take it a little easy" since.
I haven't seen any indication of medical attention — a boot, a wrap, whatever — to the injury. Could mean Clay dodged a bullet. Could mean there's no rush to bring him back, with a bye after the UW game on Saturday, meaning he could take the next two weeks to get healthy if necessary.
Clay leads the Ducks with 33 tackles through five games, 20 unassisted. Only three of his teammates have more than 20 total tackles, much less 20 unassisted.

subset: commoncrawl


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Pumpkin Festival at Shepherd's Cross
Oct 01, 2015 - Oct 31, 2015
Shepherd's Cross, Claremore, OK 74017
Celebrate fall with pumpkins, hayrides and harvest educational activities at Shepherd's Cross, an authentic working ... read more...
Nature/Agriculture Event, Fall Festivals & Events
Oct 03, 2015 - Oct 31, 2015
P Bar Farms, Weatherford, OK 73096
Visit the annual P Bar Farms Haunted Maze in Weatherford for a scary good time. When it gets dark on certain nights in ... read more...
Fall Festivals & Events
Oct 10, 2015
Belvidere Mansion, Claremore, OK 74017
The Fall Old Home Tour in Claremore features four unique homes open to the public. Take a tour of these beautiful ... read more...
Tour Event
Oct 16, 2015 - Oct 17, 2015
2301 N Sioux Ave, Claremore, OK 74017
Visit the Autumn Leaves Quilt Show in Claremore to browse beautiful quilts made from local quilters. This fun and ... read more...
Craft/Hobby Show
Greenwood Cemetery Sunset Tour
Oct 19, 2015
Hwy 54, Weatherford, OK 73096
Learn the tales of early area pioneers who are buried in the Greenwood Cemetery at this free, educational tour. This ... read more...
Tour Event, Educational Event
Oct 29, 2015
Elk City Retail District, Elk City, OK 73644
Elk City's Moonlight Madness offers a scary good time for children and pets alike. The event kicks off with a ... read more...
Children's Event
Nov 04, 2015 - Nov 07, 2015
Will Rogers Memorial Museum, Claremore, OK 74017
Will Rogers Days celebrates the November 4, 1879 birth of Will Rogers, Oklahoma's favorite son, as well as the ... read more...
Fairs & Festivals
Will Rogers Days Chuck Wagon Cook-Off
Nov 07, 2015
Claremore Expo Center, Claremore, OK 74017
The Will Rogers Days Chuck Wagon Cook-Off is a special food event that happens at the Expo Center during Will Rogers ... read more...
Food Event, Western Heritage Event
Elk City Christmas Craft Show & Gift Expo
Nov 14, 2015 - Nov 15, 2015
Elk City Convention Center, Elk City, OK 73644
Visit the 27th annual Elk City Christmas Craft Show & Gift Expo for two days of fun and shopping. This event ... read more...
Craft/Hobby Show
Nov 20, 2015 - Nov 21, 2015
Historic Downtown, Claremore, OK 74017
Dickens on the Boulevard is a Victorian-themed holiday festival in historic downtown Claremore. Visitors to ... read more...
Winter Holiday Event, Living History Event
Email: email@example.com


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Last year, Cox radio flipped former hip-hop station 106.7 FM (KPWT) to a largely conservative commercial talk format. Preceding the flip was lots of stunting promising Christmas music. Tee-hee.
Then came the real plan: Hosts — such as Laura Ingraham, Dr. Laura, Michael Savage and Clark Howard — were supposed to float your boat.
Clearly, they didn't float it enough. Just 10 months later, the station wiped out the talk and started making promises again — appropriately on April Fool's Day. Amid clocks ticking on the air, a voice hints at a format that should please a lot of S.A. listeners. (Where did I hear that before?)
This time, however, cash is being offered if your guess as to what'll replace it is close to the real thing. Five winners will be awarded $1,000 each for their wily guesses.
To participate, search 106.7 and click on Mystery on Facebook.
Or if you prefer your radio without such tiring fun and games, listen in at 5 p.m. Monday and see what Cox is handing you now.
Some in the know are guessing a return of hip-hop. Another radio entity tells me Gen X radio — grunge, hip-hop, alternative, modern rock — is hot so it could be 106.7 will go that route.
However, the radio buzz sites indicate that Cox registered 1067river.com Thursday. And since Cox already owns the Atlanta "River" station 97.1 — home of "Classic Hits" of the Sting, Elton John and Tom Petty variety — I'm betting 106.7 will go the "all classic hits, all the time" route.
But you can bet — in this cost-cutting climate — they won't be paying local DJs.
Cox programming pooh-bah Virgil Thompson wasn't talking Thursday except to confirm talk had gone bye-bye and that I should tune in Monday to find out the rest..
Meanwhile, some folks — namely, those who had shows on talk 106.7 — learned the news. . .the hard way. Steven Stoli wrote: "Talk about an April Fools surprise. Me and Wayne (Harrell) my co-host on the 'Dig In Garden Show' on FM 106.7 got a call from station reps that the format was changing and it would no longer be talk format. We had to ask three times if this wasn't a joke. So when we tuned into the station today. . . nothing but a clock ticking. OK, no joke. "
Stoli went on to say it was a shame as their gardening show "was rapidly gaining listeners and callers. We were about to go to a two hour show…. but."
P. S. If you were a fan, here's a silver lining: "We are not completely out of the media," Stoli said. "We will start producing gardening videos for "Good Day SA" (on KENs) this month.
Photo of Ingraham's book courtesy of Amazon


text:
Health Service Journal
26 November 2009
View all stories from this issue.
A&E services under threat in £20m disputeTwo services that could ease winter pressures on accident and emergency at an acute trust in the West Midlands are under threat from a funding row.
Acute sarcasmHSJ reported in late September that Worcestershire Acute Hospitals Trust's foundation application was being blocked by health minister Mike O'Brien.
Alastair Henderson leaves NHS EmployersNHS Employers deputy director Alastair Henderson has been appointed Academy of Medical Royal Colleges chief executive.
Andy Burnham welcomes staff sickness reportHealth secretary Andy Burnham has welcomed recommendations designed to improve the health and wellbeing of NHS staff.
Assisted suicide: life and death in the balancePolicy on the position of anyone who assists in a suicide is slowly changing, but health and care professionals must not run ahead of the law, says Corinne Slingo
Book Review: Branding YourselfIt is best to let people know who you are from the start, says Hannah Lowry
Brave new title for QIPPThe task of running the NHS with likely funding cuts appears to have gained yet another catchy title.
Charities warn Andy Burnham of preferred provider fearsHealth secretary Andy Burnham has been warned he is risking the future stability of the voluntary sector by abandoning the "any willing provider" model.
Children's mental health provision criticisedChildren in Wales are being let down by inadequate mental health services, with some young patients treated on adult wards, a multi-agency report has claimed.
Community Services Bidder Information EventGreat Yarmouth and Waveney
Confused patients appeal for simplified NHS regulationHealth profession regulators should standardise how they work, or even merge, to improve safety, patient groups have said.
Conservative win could kill local NHS shake-up plansThe Conservatives have pledged to scrap current government proposals for reconfiguration in major services if they are voted into power. What could this mean for the many local changes already being deliberated? Alison Moore reports
DH accepts full staff health and wellbeing recommendationsEvery NHS organisation must draw up a plan to improve the health and wellbeing of its staff, following the acceptance of the Boorman review's recommendations in full by the government.
DH and unions thrash out deal on transfer of NHS staff pensionsThe Department of Health and unions are close to a deal on allowing NHS employees who transfer to the private sector to keep their NHS pension, HSJ has been told.
Dial something beginning with 9 for emergencyEnd Game has identified a potential gap in the Department of Health's awareness campaigns.
Diversity ambassador appointedNHS Nottinghamshire County assistant director of strategy Kate Davies has been made a national ambassador for increasing diversity in public appointments.
Doctor licensing requirement comes into forceDoctors in the UK must be licensed as well as registered with the General Medical Council following changes introduced this week.
Doggy bagEnd Game's colleagues were invited to take part in a "unique" fundraising auction while attending the Family Planning Association's annual dinner and dance.
Ex-NHS boss backs Tory reformsA Conservative policy to free the health service from Department of Health control is being backed by former NHS boss Lord Crisp.
Future NHS chief execs 'put off' by TV dramasYoung people may be discouraged from pursuing careers in the NHS by watching TV hospital dramas full of staff acting unprofessionally, the new chief executive of Mid Staffordshire Foundation Trust has said.
Government to accept NHS staff sickness planThe government is set to accept a range of recommendations to drive down staff sickness and absence in the NHS.
GP spending role debatedPractice based commissioning should be replaced by consortia with "real" budgets but comprising clinicians from both primary and secondary care, according to a think tank report.
Health service involvement 'could help curb domestic abuse'Closer links between independent domestic violence advisers and health services could prevent further abuse against women facing severe domestic violence, a report has found.
Hospital cleaning firm managers arrested in blackmail probePolice have raided the office of an NHS hospital cleaning company in south west London, arresting three senior managers on suspicion of blackmailing foreign members of staff.
Hospital group goes into administration following fraud trialThe private hospital group at the centre of a collapsed fraud trial earlier this year has gone into administration.
How to spot the NHS leaders of the futureWith budget pressures escalating, organisations need to identify those worth developing as tomorrow's leaders. Mike Hay explains the best way to do this
Ian Dalton's swine flu update - next steps in the vaccination programmeIn his weekly update for HSJ and Nursing Times, national director for NHS flu resilience Ian Dalton discusses the latest developments in UK swine flu preparations
Infection control measures 'ineffective'A hospital's measures to prevent the spread of infections such as C difficile have been branded "ineffective" by inspectors.
Information for improvement - tools and measures for finance and workforce managementThe NHS is entering a new phase in which resources will be tighter than ever, demands will continue to rise and quality must still be driven up along with productivity.
Jenny Rogers on managing your managerWhile millions of words are routinely given to the topic of managing subordinates, relatively few are ever devoted to how to manage upwards.
London hospital managers cleared of bullyingA report into the handling of concerns by doctors involved in the Baby P case will clear hospital managers of bullying and harassment, HSJ understands.
Map of Medicine - plot the best pathway to careA software based tool gives clinicians a picture of the ideal route patients need to take for many important conditions. Lynne Greenwood explains how it works
Marriage counselling to be offered as part of talking therapies schemeMarriage counselling will be offered as part of the government's talking therapies programme, health secretary Andy Burnham is to announce this week.
Media Watch: couples therapyOne story got blanket coverage in the papers this week, largely down to it having what is known in the trade as a good news "hook".
Michael White: the Queen's SpeechFor a seven minute royal speech which was criticised for not once mentioning what David Cameron called "the three letters that should be in any Queen's Speech" - NHS - it was quite a boisterous occasion for health and social services. So let us start on a positive party political note.
Mike O'Brien paints 'shame' profilesHealth minister Mike O'Brien has described the types of NHS managers who will be named and shamed for introducing "slash and burn" cuts.
Next year's tariff delayed until mid-FebruaryThe Department of Health has warned the payment by results tariff for 2010-11 will be delayed due to the late publication of the pre-budget report this year.
NHS boards are still not getting the messageThe latest Dr Foster Intelligence analysis of trusts' mortality rates contains both good and baffling news.
NHS constitution: report says staff need more enthusiasmThe NHS constitution suffers from a "vision gap" and is having less impact than strategic health authorities think, according to research commissioned by the Department of Health.
Nick Bosanquet: history offers the NHS survival skillsAs rising costs and a tidal wave of public expectations push the NHS towards a new funding crisis, managers would do well to study the lessons history offers
North London acute trusts considering mergerTwo hospital trusts in north London are considering a merger.
Out of hours contact can prevent unnecessary admissionsPeople with long term conditions who can contact a clinician fast may avoid going into hospital, reports Alison Moore
Patient safety reporting still fails to reach boards in 1 in 10 acute trustsOne in 10 hospital trusts have confessed to not regularly reporting patient safety and outcomes at board level, more than a year after Lord Darzi's next stage review said care quality should be "at the heart of the NHS".
Pragmatism versus populism will prove a tough test for the ToriesAdjudicating on service reconfigurations will prove a tough test for an incoming Tory government.
Queen's Speech outlines personal care plansPlans to offer free personal care to the 280,000 people with the "highest needs" were outlined as part of the Queen's Speech today.
Scottish health boards urged to work more closely with councilsSir John Arbuthnott has recommended closer working between Scottish councils and health boards as part of his review of shared services across the Clyde Valley.
Scrabble championAs if working in the health service were not sufficiently challenging, End Game has learnt that one NHS back room worker has bigger fish to fry.
Simon Stevens on incentives for doctors vs incentives for patientsStop the presses for some shock news. British GPs are happy. At least relatively speaking.
South Essex provider shortlist cut to threeSouth Essex Partnership University Foundation Trust has withdrawn from a contest to take over the management of the provider arm of NHS South West Essex.
Steve Bundred to leave Audit CommissionAudit Commission chief executive Steve Bundred has given notice of his intention to stand down during the first half of 2010.
Swine flu could lead to shortage of children's intensive care bedsThe number of children suffering from swine flu and other respiratory infections this winter might cause a shortage of NHS intensive care beds.
Tories pledge rapid emergency budgetThe Conservatives would hold an "emergency budget" within 50 days of winning a general election, David Cameron has said.
Trust in court over patient safetyA hospital trust faces prosecution over health and safety breaches linked to the death of a mother who had just given birth.
Trust may halt weekend surgery to cut costsA Scottish hospital may close its surgical ward on Saturdays and Sundays to cut costs, although NHS managers stressed its emergency surgery service would continue.
Under-fives to receive swine flu jabThe NHS is to begin vaccinating healthy children under the age of five against swine flu, it has been confirmed.
Wide variations in A&E treatment speedThere are significant regional variations in the speed at which patients are dealt with by their local accident and emergency department, according to a report from the NHS Information Centre.
Your Humble Servant: election gamble'There is no easy or predictable way of knowing how to please Labour and live to tell the tale'


text:
Add your own review
Rating: 5 / 5
THis bright yellow pad is amazing.It is VERY thin, and I cannot recommend it as your only pad, but it is excellent and very durable. A good option for using under and inflatable 3/4 pad in the shoulder seasons. I have had one for over 7 years, and it has held up amazingly well after tons of use on expeditions.I work at an outdoor school, and I order a handful every season, and when co-workers see this thing, they buy it on the spot.It's recommended if you plan to camp on snow in a "summer" environment. I teach on the glaciers of alaska in the summer, and I use a Pro-Lite 3 on top of a MEC evazote 5-mm "bivy" pad is an excellent system.Here's a link to the MEC web site:http://www.mec.ca/Products/product_detail.jsp?PRODUCT%3C%3Eprd_id=845524442094583&FOLDER%3C%3Efolder_id=2534374302701645&bmUID=1163431149644Gear Notes: Zotefoams Evazote Bivy Sleeping PadWeight: 175 grams6.1 ounces $13 canadian doahlors (shipping down the US is expensive, buy a bunch and sell 'em to yer pals)This 5-millimetre thick foam pad has good resiliency thanks to its high 18 percent EVA content. Its smaller size makes it a good choice for surprise bivies. Evazote pads are physically blown with pure nitrogen gas for durability. Flexible to –70 degrees Celsius, it's also abrasion and UV resistant. • Dimensions are 150 x 50, with a 5-mm thickness. • R-value is 0.66.ALSO - - - THere is another pad that's similar, The Gossamer Gear ThinLight Insulation Pad, it's lighter and less expensive, but it's not as durrable.
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text:
Netbackup 7.5 cat_export -all - staging execution does not stop
We were running cat_export -all -staging to backup to flat file. We noticed that the db.backup folder was created. However, the process cat_export still running for very long time. In the end, we stop the process by pressing CTRL-C.
Is it normal for cat_export to run for very long time?
Comments 5 Comments • Jump to latest comment
i have run this command on a NBU server with 200 clients and approximatively 60 Gb of catalog.
it was terminated in 30 sec. I think this is not normal to terminate this command with control C
I have not tested this command in production.
Therefore, I tried to use this command because i have to merge 2 netbackup in one.
old server keep backup images. I would like to import this Catalog images on the new one.
Does anyone have tried this in production environment?
Do not do this - you will cause catalog inconsistanciies in the DB.
The catalog can not be merged by any method, apart from using a Symantec parnter to carry out the work.
It is not supported to try it yourself, it will not work, and you will possibly lose data.
If you want to merge two catalogs together you should really seek professional services - there are a number of trained partner consultants in each country to do this for you
Ask your Symantec Account manager to put you in touch with one to deal with all of this for you
Hope this helps
Authorised Symantec Consultant . Expert Partner.
Don't forget to "Mark as Solution" if someones advice has solved your issue - and please bring back the Thumbs Up!!.


text: > View Product Details Please select the size of the product. Please enter valid quantity. Sablina mint green chalcedony round disc necklace overview details Retail: $2,160.00 Bluefly: $1,189.00 10% Off : $1,070.10 color : We're sorry. This style is currently unavailable. Yellow Gold / Mint Green Artist Natasha Wehba draws from a world of inspiration to create her contemporary fine jewelry line, Sablina. Delicate designs, beautiful stones and gold vermeil in lightweight settings that will make you never want to slip off your dazzling gems. Color: Yellow Gold / Mint Green Polished 18k yellow gold plated vermeil lightweight setting Delicate double rolo chain with white sapphire pave 'S' details White sapphire pave border stones with approximate 1.42 cttw Faceted mint green chalcedony stone with approximate 6.49 cttw; faceted green amethyst stones with approximate 6.79 cttw Lobster clasp closure Measures 19'' long with 3½'' drop from front of the neck Discs measures 2'' long x 1'' at widest All measurements are approximate 14 Day Return Policy; returns must be received within 14 days. No returns will be accepted on international orders. See FAQ for more details. 18k Yellow Gold Vermeil / Mint Green Chalcedony / Green Amethyst / White Sapphire; Imported; style#321449101


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Archive for the 'Gaylord' tag
SIA Flashback – The Big Apple's Big Auto Shows
Sure, most of the big show car debuts take place at the Detroit auto show these days, but the New York auto show is no slouch, especially with 110 years of history behind it. In SIA #75, June 1983, Audrey M. Snediker reviewed that history and showed us some of the more unique and eye-catching cars that have graced the New York auto show.
Quick note: Longtime HCC readers will recall the photographs of the 1940 Packard at the New York auto show that we ran in Lost and Found, HCC #3. From the article, we see that those photos were taken in an attempt to win that Packard. Always nice to put some context with some old pictures.
SIA Flashback – 1956 Gaylord: A Grand Turismo in the American Manner
The Gaylord, when mentioned nowadays, draws a lot of criticism for its, um, quirky looks. (It's a Brooks Stevens design – what'd you expect?) Most people trot out the big-headlamp prototype, yuk it up, and move on. But after reading Richard Langworth's history and description of the Gaylord in SIA #61, February 1981, you realize that it was actually a well-engineered car, not simply some crackpot's automotive fantasy, and it was actually at one point headed toward production.


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Imagine spending the perfect summer day in the sun: Feet dangling in cool swimming pool waters, cocktail in hand, and Deep Purple's 'Smoke on the Water' emanating from the Ivation Waterproof Bluetooth Swimming Pool Floating Speaker. A host of advanced features makes our PoolPower such a great accessory to a fun, relaxed day.
- Rugged, IPX 7 waterproof ball enclosure
- Swims/floats in pool keeping speaker above water
- 33-foot Bluetooth 3.0 wireless range
- Super cool blue mood lighting
- Runs on 6 AA alkaline batteries
The PoolPower amplifier is powered by 6 AA batteries (not included) and cranks out a splashing 5 watts of crystal-clear sound. We've designed all the internals in a way that distributes weight very strategically. The result is a center of gravity that steadies the ball when in water and keeps the speaker right-side-up even in a wave pool.
A brightly colored orange belt runs all the way around the ball's diameter for easy spotting from across the pool. The color also adds excitement and evokes sunny days. So we daresay that the Ivation Waterproof Bluetooth Swimming Pool Floating Speaker makes a great holiday gift, no matter the time of year.Product Features
Shipping Weight:2 pounds


text:
Bacteriophages (phages) are widespread in the environment and play a crucial role in the evolution of their bacterial hosts and the emergence of new pathogens.
LSB-1, a reference coliphage strain, was classified as a member of the Podoviridae family with a cystic form (50 ± 5 nm diameter) and short tail (60 ± 5 nm long). The double stranded DNA was about 30 kilobase pairs in length. We identified its host range and determined the gp17 sequences and protein structure using shotgun analysis and bioinformatics technology.
Coliphage LSB-1 possesses a tailspike protein with endosialidase activity which is probably responsible for its specific enteroinvasive E.coli host range within the laboratory.
Bacteriophages (phages) are widespread in the environment and play a crucial role in the evolution of their bacterial hosts and the emergence of new pathogens. They have enormous potential for the development of new drugs, therapies and environmental control technologies, such as natural, non-toxic alternatives for controlling bacterial pathogens. Recent interest in phages has been stimulated by studies that demonstrate the efficacy of phages in preventing and treating infections [1-3].
Phages are readily isolated from water samples in the environment. Some of the isolated phages have shown broad-host range interaction with the bacterial isolates and others have shown either species or strain level specificity. Both polyvalent phages and non-polyvalent phages are morphologically and genetically diverse [4,5]. They are efficient at host recognition but there is no single method of adsorption, and different phages employ different strategies [6,7]. Identification of the mechanisms of adsorption and the host ranges of different phages may allow genetic manipulation to alter the phage host binding profile artificially. To gain a better understanding of the biological properties of phages, we have sequenced the genome of the gp17 from phage LSB-1, which was isolated from sewage samples. We determined its host range and analyzed its 3-dimensional structure to identify possible functional domains.
Coliphage morphology
The LSB-1 phage has a cystic form of 50 ± 5 nm in diameter, with a short noncontractile tail 60 ± 5 nm long (Fig. 1). It is classified as a member of the Podoviridae family [8-10].
Figure 1. Electron micrograph of phage LSB-1. Electron micrographs of the phages with a short, stout tail. The polyhedral nature of the viral head is shown.
Nucleic acid characterization
LSB-1 coliphage nucleic acid was sensitive to Dnase I, but resistant to Rnase A and S1 nuclease (Fig. 2). It was concluded that all the extracts contained double-stranded linear DNA.
Figure 2. Agarose gel electrophoresis of DNA of phage LSB-1. Lane 1: whole genome DNA digested by Nhe I. Lane 2: whole genome DNA without digestion. Molecular size markers (kb) are HindIII-digested lambda DNA.
Preliminary overview of the coliphages genome
The shotgun sequencing and a primer-walking method was used to assemble the whole linear LSB-1 genome of approximately 30 kb. Fifteen major potential ORFs were identified, all of which could be assigned functions based on homology with corresponding genes in the K1F coliphage in a BLAST search (Fig. 3 and 4).
Figure 3. Comparative genomic arrangements of coliphage LSB-1 with K1F. Genome of coliphage LSB-1 is aligned. Arrows indicate functions of the ORFs.
Figure 4. Comparative genomic arrangements of coliphage LSB-1 with K1F. Genome of coliphage K1F is aligned. Arrows indicate functions of the ORFs.
Genome relationship of LSB-1 and other phages
We chose four important proteins, capsid protein (gp10), tail tubular protein (gp12), internal virion protein D (gp16), and endosialidase (gp17), which are present in phage T7 supergroup members, to build phylogenetic trees. As shown in Fig. 5, 6, 7 and 8, trees built using different proteins are broadly similar. Coliphages LSB-1, EcoDs1, and K1F closely clustered towards the end of the group and phages T7, T3, phiYeO3-12 and K11 cluster within another branch of the same group. These data suggest that LSB-1 is most closely related to the K1F-like phages, and should be classified as a new member of the K1F supergroup.
Figure 5. Phylogenetic analysis of the capsid protein (gp10) from seven phages in the T7 supergroup. The alignment of whole sequence was used to construct the neighbor-joining tree. The scale bar represents 0.05 fixed mutations per amino acid position. Bootstrap values based on 1000 computer-generated tree are indicated at the nodes.
Figure 6. Phylogenetic analysis of the tail tubular protein (gp12) from seven phages in the T7 supergroup. The alignment of whole sequence was used to construct the neighbor-joining tree. The scale bar represents 0.05 fixed mutations per amino acid position. Bootstrap values based on 1000 computer-generated tree are indicated at the nodes.
Figure 7. Phylogenetic analysis of the internal virion protein (gp16) from seven phages in the T7 supergroup. The alignment of whole sequence was used to construct the neighbor-joining tree. The scale bar represents 0.05 fixed mutations per amino acid position. Bootstrap values based on 1000 computer-generated tree are indicated at the nodes.
Figure 8. Phylogenetic analysis of the endosialidase (gp17) from seven phages in the T7 supergroup. The alignment of whole sequence was used to construct the neighbor-joining tree. The scale bar represents 0.2 fixed mutations per amino acid position. Bootstrap values based on 1000 computer-generated tree are indicated at the nodes.
Gp17 DNA sequencing and function analysis
As shown in Fig. 9 and 10, the secondary structure of gp17 protein was composed of 33.10% Alpha helix (Hh), 25.25% Extended strand (Ee) and 30.29% Random coil (Cc).
Figure 9. Secondary structure prediction of gp17 protein.
Figure 10. Supplements and reports of Fig. 9, the secondary structure of gp17 protein comprised 33.1% Alpha helix(Hh), 25.25% Extended strand(Ee) and 30.29% Random coil(Cc).
The PHYRE program generated several possible templates classified as best fit when the gp17 sequence was submitted. All of these templates included the sequences of hydrolase as one of its domains. It also provided the SCOP codes, E-values and estimated precision values for the predicted models. Table 1 shows these parameters provided by different templates.
Table 1. Parameters provided by different templates
The endosialidase 3-dimensional structure was chosen to generate coordinates for the Gp17 of LSB-1 based on an E-value of 1.1 and an estimated precision of 70%. Using the PHYRE program, it was difficult to find another closer coordinate template for Gp17 of LSB-1 even though an E-value of less than 2e-6 was considered [11-13]. Gp17 of LSB-1 included endosialidase amino acid residues from Thr290 to Glu713, with the with the exception of forty-one residues (Ser 465 to Trp475, Tyr497 to Val512, and Lys543 to Leu562). These forty-one residues did not match corresponding sequences within the prediction server. The Gp17 3-dimensional structure model predicted two domains: Domain A with hydrolase activity connected by an intervening unstructured sequence to Domain B. The later domain may have a host-anchoring function. A worm algorithm representation of the model is shown in Fig. 11. Domain A, the larger of the two domains, includes residues Thr290 to Phe528 and corresponds to the N-terminal domain of endosialidase. It comprises 4 α helices and 9 β strands with intermittent unstructured intervening regions. The arrangement is characteristic of crystallized hydrolase. Domain B is composed of 1 α helix and 9 β strands with intermittent unstructured intervening regions. It includes residues Gln542 to Glu713 and corresponds to the C-terminal domain of endosialidase. There were no predicted structural constraints in the connecting region between domains A and B which included the residues of Tyr529 to Asp541.
Figure 11. Computer-generated 3-dimensional modeling of gp17 protein. Worm algorithm representation of the 3-dimensional model showing the two main domains. The larger Domain A is homologous to hydrolase sequences. The smaller Domain B is homologous to the sequence of the anchoring domain.
The molecular surface structure of the Gp17 is presented in Fig. 12. It shows the catalytic pocket in Domain A comprising the catalytic triad, Glut405, Arg415, and Arg487, identical to that found in the endosialidase family of enzymes. Domain A is shown topographically in front of Domain B. The connecting region was difficult to see in this representation because of its opaqueness. Fig. 13 and Fig. 14 show the worm algorithm structures of Gp17and the KIF endosialidase respectively.
Figure 12. Computer-generated 3-dimensional modeling of gp17 protein. Molecular surface presentation of the predicted catalytic pocket of endosialidase. The active site triad (yellow), Glut405, Arg415 and Arg487, is the amidase reaction site of endosialidase.
Figure 13. Worm algorithm representation of the model of endosialidase of K1F.
Figure 14. Molecular surface presentation of K1F endosialidase. The active site triad (yellow) is Glut581, Arg596 and Arg647.
Previous studies have suggested that gene 17 from the T7-like and K1F-like phage may be playing an important role in host range recognition processes [14,15], but little work has been done on comparing their molecular characterization. K1F-like phages are known to possess tailspike proteins with endosialidase activity that degrades polySia with high substrate specificity. These tailspike-associated enzymatic activities enable the phages to penetrate the capsular layer and are important determinants of the bacteriophage host range [16]. The T7-like phage encodes a tail fiber protein that specifically recognizes and binds to lipopolysaccharide [17] and recognizes E. coli B and many E. coli K-12 strains.
It was expected that molecular characterization would provide evidence for a host adsorbing mechanism of coliphage LSB-1. We found that the LSB-1 has some common features of the phage K1F supergroup. A tailspike protein with endosialidase activity is implicated in allowing a specific enteroinvasive E.coli host range. Insertion of such an endosialidase gene into a non-polyvalent virulent phage may artificially increase its host range to enteroinvasive E.coli. Using manipulation of the phage genome to kill pathogenic bacteria has broad implications for the welfare of both man and animals. Our results may inform new ways of genetic manipulation of phages to alter their host binding profile.
Materials and methods
Purification of phage particles
Bacteriophage LSB-1 was propagated in liquid culture. The EIEC strain 8401 was infected with phages at a multiplicity of infection of 0.1. Following complete lysis of the host cells, cell debris was removed by centrifugation at 4000 × g for 10 min, and phage particles in the supernatant were concentrated by adding polyethylene glycol 6000 and NaCl to achieve final concentrations of 10% and 1.0 M, respectively. Phage particles were collected by centrifugation at 8000 × g for 10 min. Pellets were re-suspended in 0.01× the original volume of sterile SM buffer (5.8 g sodium chloride, 2 g magnesium sulphate, 100 mg gelatin, 50 mL 1 mol·L-1 Tris (pH 7.5) and 945 mL distilled water). For isopycnic centrifugation, the phage suspension was placed on a cesium chloride gradient stepwise using three solutions whose densities were 1.45, 1.50, and 1.70, respectively. After centrifugation for 60 min at 150,000 × g, the phage band was withdrawn and dialyzed against 10 mM Tris-HCl (pH 7.5) containing 10 mM MgSO. The purified phage (approximately 1011PFU/ml) was stored at 4°C until use.
Host range determination
Seventeen bacterial strains, listed in Table 2, were tested for sensitivity against the isolated phages. The Spot Test [18] was used to determine the host range of the phage. Lytic activity was examined following overnight incubation at 37°C and recorded on a scale as follows: (N) no plaques, (T) turbid plaques, (C) clear plaques. To obtain an accurate estimate of relative phage lytic activity, all host range determinations were carried out simultaneously using a single high-titer stock of purified bacteriophage and all host cells were incubated at 37°C in LB medium.
Table 2. Phage and bacterial strains used in the study and host range spectrum of the bacteriophages
Electron microscopy
To examine phage LSB-1 morphology, 50 μl of purified viral stock solution was fixed by addition of 50 μl of 0.5% glutaraldehyde in 4% paraformaldehyde and a drop of this solution was placed on a carbon coated copper grid After waiting 30 min for settlement, excess liquid was removed and the grid was allowed to dry. A drop of 2% phosphotungstic acid was added for 2 min before excess was removed with filter paper before drying and then examination by TEM (Hitachi, model S-800) at an acceleration voltage of 45 kV.
Nucleic acid characterization
The method used was based upon that described by Sambrook and Russell [19]. Bacteriophage from the concentrated solutions were lysed with the addition of EDTA (final concentration 20 mmol·L-1), proteinase K (final concentration 50 μg·mL-1) and SDS (final concentration 0.5%) and incubation at 56°C for 1 h. The nucleic acid was purified using phenol, phenol/chloroform and chloroform extraction. The final aqueous phase was dialyzed overnight against Tris EDTA buffer (TE). In this method, nucleic acid yield was estimated by agarose gel electrophoresis and comparison of ethidium bromide stain intensity with known DNA standards (Hind III cut lambda phage DNA, New England Biolabs Inc, USA).
The nucleic acid extracts were diluted to a standard concentration of ~20 ng·μL-1. Approximately 250ng of each extract was subjected to digestion with DNase I (Sigma Aldrich), RNase A (Sigma Aldrich) and S1 nuclease (Promega). All reactions were terminated with the addition of EDTA (10 mmol·L-1 final concentration) and analyzed using 0.8% agarose gel electrophoresis at 5 V cm-1.
Gp17 DNA sequencing and analysis
The coliphage genome was sequenced by the shotgun method. Genomic DNA was sheared by sonication, cloned into pUC18 and sequenced with an ABI 3700 automated DNA sequencer, to give 13-fold coverage of the genome. Sequences were assembled into contigs, and gaps linked using a primer-walking technique (Kaczorowski and Szybalski, 1998) [20]. Potential open reading frames (ORFs) were predicted using ORF Finder http://www.ncbi.nlm.nih.gov/projects/gorf/ webcite and manual correction. Translated ORFs were used in a BLAST search against the Swiss-Prot http://us.expasy.org/tools/blast webcite and NCBI protein databases http://blast.ncbi.nlm.nih.gov/Blast.cgi?CMD=Web&PAGE_TYPE=BlastHome webcite. Protein secondary structures were predicted with SOPMA http://npsa-pbil.ibcp.fr/cgi-bin/npsa_automat.pl?page=npsa_sopma.html webcite.
Phylogenetic trees were constructed using Mega 4 software following published protocols [21,22].
The amino acid sequence of endosialidase was determined and compared with the protein structure family databases PDB [23], SCOP [24,25], and PFAM [26] to identify the most suitable template structure. The eventual template structure was taken from PDB. Three-dimensional models were created using PHYRE http://www.sbg.bio.ic.ac.uk/~phyre/ webcite by mapping the coordinates of the template structure with aligned residues of the endosialidase. Computer-generated three-dimensional models were viewed and analyzed using CN3 D 4.1 application software programs obtained from http://www.ncbi.nlm.nih.gov/Structure/CN3D/cn3d.shtml webcite.
In summary, a typical Podoviridae morphology and the double-stranded nature of its DNA give the coliphage LSB-1 some common features with the phage K1F supergroup. It possesses a tailspike protein with endosialidase activity which is probably responsible for its specific enteroinvasive E.coli host range within the laboratory.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
YC and HX conceived of the study, carried out the experimental work, analysis and drafted the manuscript. XM and LC participated in its design and coordination and helped to draft the manuscript. GH and ZR participated in its design and experimental work. LZ participated in coordination of the study. All authors read and approved the final manuscript.
The authors would like to thank Jinxin Ke and Wenqi Huang for their help in electron microscopy. The project was supported by National Natural Science Foundation of China (Grant No.30571637), Scientific Research Project of the Chongqing China (Grant No. CSTC, 2008AC5005) and National Key Technology R&D Program of China (Grant No. 2008BAD96B06-05).
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Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections (cSSSI)
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
The purpose of this study is to determine whether ceftaroline is effective and safe in the treatment of complicated skin infections in adults.
Bacterial Infections
Drug: IV Vancomycin plus IV Aztreonam
Drug: Ceftaroline
Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|A Phase 3, Multicenter, Randomized, Double-blind, Comparative Study to Evaluate the Safety and Efficacy of Ceftaroline Versus Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin and Skin Structure Infection
- Clinical Cure Rate at Test of Cure (MITT Population) [ Time Frame: 8-15 days after the end of treatment ] [ Designated as safety issue: No ]
Cure: Total resolution of all signs and symptoms of the baseline infection, or improvement of the infection such that no further antimicrobial therapy was necessary.
Failure: Requirement of alternative antimicrobial therapy for primary infection of cSSSI due to inadequate response, recurrence, new infection at the same site; treatment-limiting AE; requirement for surgery due to failure of study drug; diagnosis of osteomyelitis after Study Day 8; or death caused by cSSSI.
Indeterminate: Inability to determine an outcome
- Clinical Cure Rate of Ceftaroline Compared With That of Vancomycin Plus Aztreonam Treatment at TOC in the Clinically Evaluable (CE) Population [ Time Frame: 8-15 days after last dose of study drug ] [ Designated as safety issue: No ]
- Microbiological Success Rate at the TOC Visit [ Time Frame: 8-15 days after last dose of study drug ] [ Designated as safety issue: No ]
- Clinical Response at the End of Therapy (EOT) Visit [ Time Frame: Last day of study drug administration ] [ Designated as safety issue: No ]
- Clinical and Microbiological Response by Pathogen at the TOC Visit [ Time Frame: 8-15 days after last dose of study drug ] [ Designated as safety issue: No ]
- Clinical Relapse at the Late Follow Up (LFU) Visit [ Time Frame: 21 to 35 days after the last dose of study drug ] [ Designated as safety issue: No ]
- Microbiological Reinfection or Recurrence at the LFU Visit [ Time Frame: 21 to 35 days after the last dose of study drug ] [ Designated as safety issue: No ]
- Assess Safety [ Time Frame: First dose of study drug through TOC visit ] [ Designated as safety issue: No ]Comparisons of the number of participants with Adverse Events
|Study Start Date:
|February 2007
|Study Completion Date:
|November 2007
|Primary Completion Date:
|November 2007 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: Ceftaroline for Injection
Drug: Ceftaroline
600 mg parenteral infused over 60 minutes, every 12 hours for 5 to 14 days
Other Name: Experimental
|Active Comparator: IV Vancomycin and IV Aztreonam
Drug: IV Vancomycin plus IV Aztreonam
vancomycin at 1 g parenteral infused over 60 minutes followed by aztreonam 1 g infused over 60 minutes, every 12 hours, for 5 to 14 days.
Other Name: Active Comparator
Detailed Description:
Additional purpose of the study is to compare ceftaroline effectivity versus Vancomycin plus Aztreonam in the treatment of complicated skin infections in adults.
|Ages Eligible for Study:
|18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Skin and skin structure infection (SSSI) that involves deeper soft tissue or requires significant surgical intervention, or cellulitis or abscess on lower extremity which occurs in subjects with diabetes mellitus or well-documented peripheral vascular disease.
Exclusion Criteria:
- Prior treatment of current cSSSI with an antimicrobial.
- Failure of vancomycin or aztreonam as therapy for the current cSSSI, or prior isolation of an organism with in vitro resistance to vancomycin or aztreonam.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00424190
Show 52 Study Locations
|Principal Investigator:
|Ralph Corey, MD
|Duke University
No publications provided by Forest Laboratories
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Senior Vice President, Clinical Development, Cerexa, Inc
|ClinicalTrials.gov Identifier:
|NCT00424190 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 16, 2007
|Results First Received:
|October 12, 2010
|Last Updated:
|November 23, 2010
|Health Authority:
|United States: Food and Drug Administration
United States: Institutional Review Board
Italy: National Bioethics Committee
Italy: Ministry of Health
Germany: Ethics Commission
Germany: Federal Institute for Drugs and Medical Devices
Poland: Office for Registration of Medicinal Products, Medical Devices and Biocidal Products
Poland: Ministry of Health
Switzerland: Ethikkommission
Switzerland: Swissmedic
Argentina: Administracion Nacional de Medicamentos, Alimentos y Tecnologia Medica
Argentina: Human Research Bioethics Committee
Brazil: National Committee of Ethics in Research
Brazil: Ministry of Health
Brazil: National Health Surveillance Agency
Chile: Comisión Nacional de Investigación Científica y Tecnológica
Chile: Instituto de Salud Pública de Chile
Mexico: Ethics Committee
Mexico: Ministry of Health
Mexico: Federal Commission for Protection Against Health Risks
Peru: Ethics Committee
Peru: General Directorate of Pharmaceuticals, Devices, and Drugs
Peru: Ministry of Health
Romania: National Medicines Agency
Romania: State Institute for Drug Control
Russia: Ethics Committee
Russia: Ministry of Health of the Russian Federation
Ukraine: Ministry of Health
Ukraine: State Pharmacological Center - Ministry of Health
Keywords provided by Forest Laboratories:
Bacterial infection, skin
Ceftaroline acetate
Complicated skin and skin structure infection
Skin disease, bacterial
Skin infection
Staphylococcal skin infection
Staphylococcus aureus
Streptococcal skin infection
Surgical site infection
Additional relevant MeSH terms:
Bacterial Infections
Communicable Diseases
Anti-Bacterial Agents
Anti-Infective Agents
Pharmacologic Actions
Therapeutic Uses
ClinicalTrials.gov processed this record on October 02, 2015


text:
Successunder JBloggers,JDate,Online Dating,Relationships,Single Life
Dear Gems from Jen,
I am a successful pediatrician who finds that the men I meet are threatened by my title and success. How do I keep from scaring away men who are eligible? – Malka
Dear Malka,
My suggestion would be to look at your profile. Does it talk more about you and your career rather than whom and what you are searching for? Are you limiting your search to men who are in your same professional sphere? Are you excluding men who might be great matches, but do not possess the same status or title that you have earned? Do you focus more on your successes and accomplishments rather than who you are? Our job titles do not define us, rather they complement us. I understand that we career women have worked very hard to get where we are, but that is only one aspect of ourselves. What do we stand for? What makes us happy? What makes us vulnerable? Who are we minus the career? What makes us different from the next picture/profile on the list? How are we unique? What qualities can we offer to a potential relationship? Refine your profile and let the real you shine through.
Secondly, men that are scared away by successful woman are lacking in their own self-confidence. It tends to threaten them. There are many eligible bachelors who are attracted to successful, accomplished women. I just don't believe you have found him yet.
Gems from Jen


text:
Hemiji Castle Floor Plan
Nijo Castle reviews and photos from real travelers and locals in Kyoto, Japan. Osaka Tourism: TripAdvisor has 40,809 reviews of Osaka Hotels, Attractions, and Restaurants making it your best Osaka Vacation resource. For Hotel Reservations Worldwide, Call 24/7 to TRAVEL. 8.1.) Coloring and Creativity Pages for Willy Wonka/Charlie and the Chocolate Factory. 8.1.) Coloring and Creativity Pages for Willy Wonka/Charlie and the Chocolate Factory. Azuchi Castle (安土城, Azuchi-jō ?) was one of the primary castles of Oda Nobunaga. It was built from 1576 to 1579, on the shores of Lake Biwa, in Ōmi Province.
sarai givaty wiki image search results
Meval Castles Home Page
Hemiji Castle Floor Plan
- We bring up to date with on the news of this hostel and tour information in Osaka, event in Osaka, sightseeing information in Osaka.
- Japan, known as Nihon or Nippon (日本) in Japanese, is an island nation in East Asia.
- Nijo Castle, Kyoto: See 823 reviews, articles, and 508 photos of Nijo Castle, ranked No.13 on TripAdvisor among 326 attractions in Kyoto.
- Card Modeling FAQ Appendix: More Sources for Card Models Below are listed a number of possible sources for card models.
- Winnekenni Castle – This is a cute little castle located in Haverhill Massachusetts.
- It is almost 150 years old and has endured a lot. Yet it still remains.
The following registrations with the relevant authorities and
Himeji-jo is Japan's most impressive castle. For Hotel Reservations Worldwide, Call 24/7 to TRAVEL. Japan, known as Nihon or Nippon (日本) in Japanese, is an island nation in East Asia. Open source travel guide to Kagoshima, featuring up-to-date information on attractions, hotels, restaurants, nightlife, travel tips and more. And I think it will go here, (on the left of the two oil paintings), mirroring the sandblasted glass on the right of them, although not on the same scale. Japan Itinerary 14 Days – Tokyo, Mt Fuji, Kyoto, Osaka, Nara, Himeji and Hiroshima. This Japan itinerary will let you experience the best of Japan.
More information about Hemiji Castle Floor Plan on the site: http://
Chichu Art Museum (ellen's attic) Tags: art japan museum architecture
Japanese castle – Wikipedia, the free encyclopedia
Images for himeji castle floor plan image search results
Floorplan Of The Castle Overviewof 3d World – AxSoris.com
July 2, 2013 / admin / 0
Categories: Plans


text:
Welcome to CommonWheels! We are excited to get up and running for our 2015 season. See the calendar to the right for our upcoming events. Keep in touch with us by signing up for our monthly newsletter updates, and follow us on Facebook and Twitter @CommonWheelz
About Us
CommonWheels is an Allston-based bicycle collective focused on building a community of happy, safe, educated riders though workshops, group rides, and our flagship program, Open Shop. Read more about our mission here.
Support Us
Want to support our mission? Donate Now! Or join us on the street:
Join Us
Open Shop is a free, DIY, bike-maintenance skillshare. We provide the tools and guidance needed to keep your bike working so you can keep riding. Our goal isn't to fix your bike and send you own your way, it's to help you fix your own bike. Open Shop is also a great chance to hang out with your fellow Boston cyclists, trade stories of biking adventures, and share your own knowledge. Open Shop begins again this April!
You can also find us setting up shop at farmers' markets, running workshops complete with all sorts of pro tips, and organizing group social rides to get our community out biking together.


text:
Birmingham-- Sometimes world events make people look inward. As Barack Obama campaigned his way to the presidency, self-described lily-white writer Tanner Colby began pondering -- and then tenaciously researching -- exactly why he and other white people didn't have black friends. The reasons are complex, ranging from school policy to real estate practices to media image-making to church politics. But the former Vestavia Hills resident dives right in from the springboard of his own life, recognizing his ignorance the whole way. The result: "Some of My Best Friends are Black: The Strange Story of Integration in America." Our Southern Education Desk reporter Dan Carsen caught up with Colby not long after the author appeared on MSNBC to discuss America's persistent racial separation. A partial index of subjects and time markers is below.
~ Dan Carsen, Sept. 20, 2013
All of Dan's education reporting can be found here.


text:
Maps: Afarezirs
February 22, 2011
The Afarezirs are an archipelago of 58 islands to the wild northwest of the main island if Hârn. The full force of the westerly gales from the Sea of Itikir strike these hilly islands, and they boast many natural harbours. The poor soils and rocky nature of the islands has doomed several colonization attempts.
This map bundle includes all islands, and a post map provides an overview of the entire archipelago. While it is not formally part of Dark Rethem, it compliments that series so perfectly that it has been included.
by John Southgate
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text:
UFC 128 Picks
UFC 128: Shogun vs. Jones
Location: Newark, N.J.
Venue: Prudential Center
Broadcast: Pay-per-view, Spike TV, Facebook
MAIN CARD (Pay-per-view)
- Champ Mauricio "Shogun" Rua vs. Jon Jones (for light-heavyweight title)
- Urijah Faber vs. Eddie Wineland
- Jim Miller vs. Kamal Shalorus
- Nate Marquardt vs. Dan Miller
- Mirko "Cro Cop" Filipovic vs. Brendan Schaub
PRELIMINARY CARD (Spike TV)
- Luiz Cane vs. Eliot Marshall
- Edson Barboza vs. Anthony Njokuani
PRELIMINARY CARD (Facebook)
- Ricardo Almeida vs. Mike Pyle
- Kurt Pellegrino vs. Gleison Tibau
- Joseph Benavidez vs. Ian Loveland
- Raphael Assuncao vs. Erik Koch
Nick Catone vs. Costantinos Philippou
With only a week to go before UFC 128, the devastation in Japan has forced a lineup change with Akiyama pulling out over concerns in his homeland. Nevertheless this should still be an action filled card.
Jon Jones is easily the most hyped mma wrestler to fight in the UFC since Brock Lesnar. Unlike Brock though, Jon Jones has a high level grasp on mixed martial arts and even though Shogun Rua was once considered the best pound for pound fighter, Bones Jones is the favorite in this fight. How do you pick a winner in this fight? MMA purists will hardly ever go against Shogun and who wants to pick against one of the most exciting fighters ever who has yet to actually "lose" a fight. My recommendation would be to take the underdog Shogun, the #1 reason is training time. Jones is taking this fight less than 2 months after his last fight, and most title contenders get at least double the preparation and training time. These two are both great fighters and unfortunately one of them has to fall.
Bet on Mauricia Rua over Jon Jones at Bodog +165 or Bet on Jon Jones over Mauricia Rua at Sportsbook.com -200
Urijah Faber finally makes his UFC debut and will be a heavy favorite over Eddie Wineland. Though Eddie is on a 4 fight win streak with back to back knockout of the nights, it is extremely tough to knock out Faber. There is upset potential, but very slightly as Faber is simply too well rounded. Look for Urijah to take him down and keep him there.
Bet on Urijah Faber over Eddie Wineland at 5Dimes -420 or Bet on Eddie Wineland over Urijah Faber at BetUS +325
Dan Miller will be the replacement for Akiyama in a fight vs Nate Marquardt. Since this is not a title fight or a direct #1 contenders match, Nate Marquardt will win. He is an unbelievable fighter but only loses in clutch fights. Not only that, Nate's wrestling is far superior to that of Dan's and should be able to control the match.
Bet on Nate Marquardt over Dan Miller at 5Dimes -350 or Bet on Dan Miller over Nate Marquardt at Bodog +260
On the other hand brother Jim Miller is on one crazy hot streak with 6 wins in a row. Facing him will be the UFC debut of Kamal Shalorus. Jim Miller has way too much octagon experience to lose this fight to Kamal. His all around great fighting skills will be too much to handle and perhaps he will finally earn some title contention with a win here.
Bet on Jim Miller over Kamal Shalorus at Sportsbook.com -245 or Bet on Kamal Shalorus over Jim Miller at 5Dimes +210
I don't know the last time I figured Mirko CroCop would win a mma fight, and this time is no different. Brendan Schaub is a rising star in the heavyweight division and once again Mirko is a gateway fighter in this stage of his career. Crocop is no longer crocop, and Schaub can sure throw a mean overhand. Brendan will catch him here and hopefully put an end to Filipovic's illustrious career.
Bet on Brendan Schaub over Mirko Filipovic at Sportsbook.com -240 or Bet on Mirko Filipovic over Brendan Schaub at 5Dimes +230
Also a very special promotion for Canadian mma bettors only on Betfair.
The Sports Exchange customer who has the highest overall net profit on UFC 128 (all markets combined) will receive 1 MMA (private suite) ticket for UFC 129, the MMA event at the Rogers Centre in Toronto on April 30th (valued at around $1000). Along with the ticket, Betfair will also cover all travel and hotel accommodations for the event. Sign up for this promotion today!Tags: 5Dimes, BetUS, UFC Picks
Posted in MMA Betting News | Comments Off on UFC 128 Picks


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Buttermilk is the secret ingredient that makes fried chicken so flavor-packed and bursting with juices. What's the main ingredient in a classic rich, tangy ranch dressing? Buttermilk. So, the ranch marinade, with a hit of chilies, on these chicken skewers goes a loooong way to have you begging for more tasty bird on a stick. And I suppose we can't ignore the fact that wrapping it in bacon certainly doesn't hurt.
PREP TIME: 1 to 3 hours, to marinateCOOK TIME: 20 minutesRECOMMENDED PELLETS: Hickory or MesquiteSERVES: 4
1/2 cup ranch2 to 3 tablespoons chile sauce like Sambal1/2 teaspoon garlic powder1/2 teaspoon dried oregano4 chicken breasts, cut into 2-inch cubes1 red onion, cut into large chunks1 green pepper, cut into large chunks1 red pepper, cut into large chunks8 slices bacon8 skewers
Mix together the ranch, garlic powder, oregano and chile sauce, in a large bowl making it as hot as you like/can stand.
Add in the cubed chicken, tossing to thoroughly coat all of the pieces of chicken. Let the chicken marinate for 1 to 3 hours. If you're using wooden skewers, soak the skewers in water during this time to keep them from burning.
When ready to cook, start the Traeger on Smoke with the lid open until the fire is established (4 to 5 minutes). Preheat to 400 degrees F with the lid closed for 10 to 15 minutes.
Start assembling your skewers. First slide on a wedge of onion and a pepper or two. Next thread on a slice of bacon, starting at the end. Follow with one piece of chicken.
Turn the skewer 180 degrees and thread the bacon on the skewer again, followed by another piece of chicken.
Keep doing that, turning the the skewer 180 degrees after the addition of each piece of chicken so that the bacon weaves around the chicken pieces. Throw in a pepper or two into the mix and finish on the other end with a piece or two of pepper and a chunk of onion to hold the skewers together.
Do not overcrowd your skewer - give a little room between each piece of chicken so that it cooks faster and more evenly.
Repeat the same steps with the remaining skewers and chicken.
Place the skewers on the grill grate, keeping a piece of foil under the end of the skewers to prevent them from burning and to make turning them a lot easier.
Cook them for about 5 minutes per side, doing a quarter-turn each time, for a total of 20 minutes. If you're worried, use an instant-read thermometer to make sure they've reached 165 degrees F.
Take the skewers off and enjoy them while they're warm with some rice, or better yet a baked potato!


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By Stephanie Ciccarelli
December 11, 2007
Curious to know which audio books made Audibles Best Audiobooks of 2007 list?
Check the titles out here!
As Audible said last week, it's been an amazing year for long-awaited novels from big-name authors, however, did those big names make the best on the audio book list as well as in print?
Here's a link to the top audio books from Audible for 2007.
The categories are as follows:
Best of 2007: Bios and Memoirs
Best of 2007: Business
Best of 2007: Classics
Best of 2007: Fiction
Best of 2007: History
Best of 2007: Kids and Young Adults
Best of 2007: Mysteries and Thrillers
Best of 2007: Nonfiction
Best of 2007: Religion and Spirituality
Best of 2007: Romance
Best of 2007: Sci-Fi and Fantasy
Best of 2007: Self-Development
Chris Picks His Favorites
Corey Picks His Favorites
Diana Picks Her Favorites
Steve Picks His Favorites
Check them out and let me know if you've listened to any of them or if you have different ideas of what should be on the lists!
StephanieRelated Topics: 2007, Audible, Audible.com, audio books, audiobooks
Not all phone systems are created equally. When people call your organization, what's the first thing they hear? Learn More!
Vox Daily offers a daily dose of voice acting news, articles, tutorials, interviews, intelligent conversation and business ideas for voice talent and voice actors.
Our feed & social options update you with special offers and news as it happens.


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About My dominance
My Dominance joined Society6 on November 24, 2011. Verified on November 25, 2011.
To add items to your wishlist, simply click the "Add to Wishlist" link from any product page.
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knut eliassenwrote a review of Nitro Anthem TLS Snowboard Boot - Men's on November 25, 2014
Great Fit.
Familiarity: I've used it several times
A medium flexing - super comfortable - durable boot that will last year after year!!! If you are looking for a mid flexing boot that will last and keep its heel hold - I would recommend this. The TLS is also great for getting in and out easily.


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Selling the Benefits of Working at Camp
Competition for college-aged staff grows stronger every year. College students feel the pressure to build their portfolios and apply for internships with major corporations. In staff recruitment, it's a buyer's market. Directors must realize that they are selling jobs, not buying staff.
Camp skills are corporate skills . . .
Advertise the benefits of camp employment when recruiting staff. Make sure you address how camp can provide students with the skills that corporate America is looking for. According to the book, Who's Going to Run General Motors?, by Kenneth C. Green and Daniel T. Seymour (Peterson's Guides, 1991), corporations are looking for the following skills from recent graduates:
- Communication
- Change
- Leadership
- Globalization
- Teamwork
- Problem Solving
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2000 7.3 powerstroke wont start in cold or?
Ok so I am new to the this forum so here it goes. first off I am sorry for the story.
I just purchased another F350 Ford I have a couple diesels and I love them until now!
I looked for a while for another 7.3 powerstroke with low miles So when I found one with 60k mles that was a one owner and lifted I bought it. Its a 2000 ford F350 crewcab longbed, 60k miles perfect shape, 10in lift 42in tires. any way,The guy drove it from Miami Fl to Oklahoma cty to meet me and then I drove it to from there to colorado.
Now when I drove it home the check engine light would come on when I was going up big hills getting on the gas then ounce n a while flicker. about 400miles into my drive the truck just dies on me at 85mph. So I pull over and it wasn't easy,I turn the truck off and boom it starts up just fine and I drive on. So I am on my way again a few miles down the road in Colorado I get pulled over for doing 95mph in a 55 I explain to the officer that I just purchased the truck and the tires must have it all screwed up and my speedo said 65mph and it did , So he lets me go with a warning and says he likes the truck! so any way I get home at 3 am its kind of cold so I look for the block heater cord and I cant find it so I went inside.
The next morning I go out side and it wont start. So I look for the plug and I found it stashed behind the bumper so I plug it in an hour latter it starts up.
So I take it directly to one of the best diesel shops in town and drop it off and asked them to check it from top to bottom and if it needs anything to fix it. winter is coming and its 15deg and getting colder. Today was -6
Again Sorry for the story.
So they go out side start it up and check it out and it starts fine they take it in the shop they don't plug it in that night and it wont start. so now the fun stuff
So they call me I tell them plug it in and it will start so they do a dio on it and a couple codes pop up.
First They said the oil is crap so the do an engine purge and cleaners and then they say it needs Glow plugs and gp wiring harness and a Glow plug relay and new valve cover gaskets, then the next day it wont start so I asked them to replace the cam positioning censor just to be safe, so they did, then they said it needed an alternator and new batteries. so they replaced the alt and the cpc and guess what it still wont start when its cold.so they replace the batteries and it still wont start.
So now 2 weeks latter $3500+ I am still having the same problem.
They start checking the wiring and found a couple bad conections at the fuel pump so they cleaned them up plugged them back in and boom it starts up again just fine runs for hours and pops no codes. They said it was sluggish so they would do a fuel system flush so They perform a fuel flush and it runs fine. Its late so they call me with the good news and tell me they want to keep it over night and check it in the am so they can just be 100% sure its ok. So today they call me and say guess what it wont start!!!!!They tell me they are going to check all of the computers and relays and pull the inner fender well out and check the pcm . So now it is still sitting in the shop and it is still not running and I still dont have my new toy. So does anyone have any ideas at all??
Again sorry for the story.
holy crap... get it out of that shop.... i was leanin towards they were hosin you but when i read this,
when you say it just doesnt start when its cold, what does it do? does it not crank or does it crank and never start?
I turn the key and it just turned over over and over,,It would never start, Then I plugged it in drove it down there just fine and now it still wont start, Now it did just make a 3600 mile trip just fine. Well one problem on the high way but thats it. They told me they pulled the inner fender well out on the driver side to clean what ever is under there.... Sorry I have never dug into the wirring on any of my 7.3s ,, Honestly I have never had this problem with any 7.3 I have had 14 of them 2 of them had over 500k miles and all they needed was the typical tranny turbo injectors glow plugs but never electrical issues!
The IDM is in the fender well. What codes was it throwing? Is the truck tuned?
the IDM is in the fender but theres nothin really to clean...
i forgot if you mentioned, does it smoke while its cranking?? what color?
when it finally starts, does it have a big cloud of smoke? and what color is that?
i know its sounds dumb on what color the smoke is but that can tell you if its fuel or oil or nothing at all...
It is black smoke,When it runs it runs perfect no smoke no lack of power, It gets good gas mileage,I drove it from Okc to Denver on 1 and 1/4 tanks of fuel so it was getting 20 or so on the road. The truck is all stock as far as the computer or major mods It has a 4in exhaust and an cold air intake.The truck has 60k miles
As I said it has been in the shop for 2 weeks so I dont know what its doing now. All I know is 2 weeks $3500 and its doing the same thing it was when I dropped it off. I am getting ready to loose it. What sucks its a friends shop and the mechanic is one of the best. There has also been a couple ford heavy line techs over there and they cant figure it out.
weird...black smoke and it wont fire...
can you get them to give you the codes they got? that could help alot...
honestly, im kinda stumped as well....
Well it was showing several different codes then they flushed the system and a couple dropped off then the glow pugs and so on and now its not throwing any codes and it wont start. Whats strange is it started happening when it got colder. HE told me they were checking all of the electrical connections just to make sure the were clean and everything was connected ok after finding the wires at the fuel pump making a bad connection..The truck has 42in supper swampers and the rattle and hum down the road. The prior owner said he never had any issues in FL. Maybe its high altitude. I do know its not a cali truck
have they checked the Glow plug system?? (sorry if you already mentioned it) bein that it was from florida, it may have bad GPs and/or a bad GPR that would never be noticed down in that warm weather....
i should have mentioned that earlier, it really sounds like thats the culprit...
EDIT: im retarded... i remember that now.... do you know for sure they changed the GP's??
Yes as I said new glow plugs new glow plug relay new and updated wiring harness.I went down there when they were installing them and I watched them for an hour or so. the also replaced the cam positioning sensor
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With the heat in full swing, summer is the perfect time for outdoor entertaining. We've been working hard on our latest digital Look Book, which is a free and easy-to-read online magazine that focuses on one gardening topic. Our latest issue, Alfresco Parties, is about enjoying life outside, with features including tips for giving your table a makeover, why you should consider building an outdoor pizza oven, cocktail recipes, installing a bocce court and other lawn games, and more!
We feature tons of pictures and ideas to pin (are you on Pinterest yet?) and clip (you can register on our site to save your favorite articles to your account) for your garden.
What kind of parties are you planning to host in your garden this year?


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The following are quick-match results from the Strikeforce: "Melendez vs. Masvidal" event, which emanated from the Valley View Casino Center in San Diego, California on Saturday, December 17, 2011.
Preliminary Fights:
-Herman Terrado def. Chris Brown via Submission (armbar) at 4:05 of Round 1.
-Eddie Mendez def. Fernando Gonzalez via Split Decision (30-27, 28-29, 29-28) after 3 Rounds.
-Devin Cole def. Gabriel Salinas-Jones via Unanimous Decision (30-27, 30-27, 30-27) after 3 Rounds.
-Roger Bowling def. Jerron Peoples via KO (punch) at 0:42 of Round 1.
-Caros Fodor def. Justin Wilcox via KO (punches) at 0:13 of Round 1.
Showtime Fights:
-K.J. Noons def. Billy Evangelista via Unanimous Decision (29-28, 29-28, 29-28) after 3 Rounds.
-Gegard Mousasi def. Ovince St. Preux via Unanimous Decision (29-28, 29-28, 29-28) after 3 Rounds.
-Cris "Cyborg" Santos def. Hiroko Yamanaka via KO (punches) at 0:16 of Round 1.
-Gilbert Melendez def. Jorge Masvidal via Unanimous Decision (50-45, 50-45, 49-46) after 5 Rounds.
For more Strikeforce and MMA/UFC coverage, visit WrestleZone's MMA sister-site, Sherdog.com.
cyborg-santosgilbert-melendezjorge-masvidalmelendez-vs.-masvidalMMAStrikeforcestrikeforce-melendez-vs.-masvidalstrikeforce-resultsHave a news tip? Attended an event and want to send a live report?


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The Wild are en route to a fourth consecutive season out of the NHL playoffs.
With 13 games left in the regular season, the Wild are eight points behind the three teams tied for the eighth and final Western Conference playoff spot.
The Wild, same as a lot of teams, aren't that far from being in the postseason, former Minnesota North Star J.P. Parise said Monday.
"But one player or two players can make a heck of a difference," he said.
One who could make a big difference next season for the Wild is Parise's son Zach, a winger with the New Jersey Devils.
Zach, 27, who played at Shattuck-St. Mary's in Faribault and has purchased a home on Lake Minnetonka, can become an unrestricted free agent at season's end. He and University of North Dakota college sweetheart Alisha Woods will be married this summer.
J.P. Parise, 70, played nine seasons for the North Stars and lives in Prior Lake with wife Donna. The Parises are an especially close family.
"I don't know where (the Wild) are with their money and signing players and what kind of payroll they have," J.P. Parise said.
The Wild are about $8 million under the $64.3 million salary cap and expected to be almost double that amount under the cap after roster changes this summer.
Zach Parise, who has 28 goals and 34 assists in 69 games for the Devils this season, can expect to become one of the NHL's top-paid players as a free agent. He's playing for $6 million this season on a one-year contract.
It could take almost $40 million over five years to sign the 5-foot-11, 195-pound left wing. It's a good bet the Wild, who need to sell tickets, would be willing to pay.
"I have no idea what Zach's going to do; he's pretty silent about it," J.P. Parise said. "I haven't inquired, and he has given no indication. I'm really being honest.
"But there are some things that are very, very important to him. His team is playing pretty good now, and I know it's important that he signs with a team that has a chance to win."
J.P. said he figures the Wild will approach Zach if he becomes a free agent.
"He's a Minnesota boy; he loves Minnesota," J.P. said. "He's going to live here after he retires from hockey. There's no question that he'll stay here.
"Money is not what's really important to (Zach). That's not the bottom line. He wants to have fun and win."
J.P. said he would like it if Zach decides to play in Minnesota.
"But I've done this, and I know how it works, how important it is to win," he said. "You've got to look forward to going to work. There were a couple years with the North Stars that it was not pleasant, no fun.
"With the Devils, they've won. It's going to be really hard for Zach. He's loyal to a fault. But then again, now it's business. And the thing about hockey, it changes from day to day."
As for Zach and the Wild, his father said, "There is always a possibility. I can assure you that he has not made up his mind. He told the Devils that he would wait until the end of the year to see what's happening."
Charley Walters can be reached at email@example.com. Follow him at twitter.com/Charley_Walters.


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CSO contracted the evaluation firm Social Impact to conduct an independent evaluation of its engagement in Kenya to prevent electoral violence (February 2012-April 2013). The final report provides credible independent determination that CSO made valuable contributions to early warning and early response networks, peace messaging, political reporting and interagency and international coordination. It provides some evidence of direct violence prevention during the election through improved early warning and response, as well as continued post-election use of some of the early warning networks, and positive lasting effects on civic cooperation with police in the coast region. It also makes some useful critical observations about how CSO could do more in future engagements to connect to longer term conflict prevention/mitigation and development, reduce misunderstandings of CSO's role, and improve its interaction with local partners. This was CSO's first external evaluation. CSO intends to conduct evaluations on all its major engagements.
Final Evaluation of CSO's Kenya Engagement (February 2012-April 2013) Public Report [1430 Kb]
At a massive youth soccer tournament last weekend in Nairobi, the competition was peaceful, and the hope in Kenya is that the election season also will be peaceful. Kenyans want to avoid the kind of violence that occurred after the 2007 elections. In Nairobi's Mathare slum, one of Africa's poorest and largest and a hotspot of violence in 2007, more than 20 people have died as a result of inter-ethnic fighting in recent months. More»
The Kenyan elections are fast approaching, and CSO is promoting peaceful, fair elections through a network of strategic partnerships with the local population. CSO has been working alongside the U.S. Embassy, the Kenyan national government, and a number of local civil society organizations on conflict prevention and electoral security. More»
In early 2013, Kenya is set to conduct its first round of presidential elections since the violence-marred 2007 elections. Despite many resiliencies, underlying sources of conflict and grievances persist.
A joint CSO-USAID team deployed to Nairobi in April 2012 to help the U.S. Embassy develop plans focused on helping Kenyans carry out peaceful and credible elections, advance their reform agenda, and prevent or mitigate conflict leading up to and beyond the elections. The plan will help the United States prioritize its actions and further define possible areas for CSO assistance.


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Dan Diamond
What's Wrong With Us? Wizards Try to Explain
►Dan Diamond | Dec 28, 2012
How do the Wizards explain what ails them? How can they? TAI's Dan Diamond attempts to peel back the layers of losing.
What's Wrong with the Wizards?
►Dan Diamond | Dec 27, 2012
Jan Vesely probably isn't the (only) answer. For three straight years, they drafted high in the lottery, nabbing a trio of coveted players: A sure-fire star who'd dazzled college basketball in...
DC Council Game 26: Wizards 84 vs Cavaliers 87: Shelvin Mack Back, But He's No Irving
►Kyle Weidie | Dec 27, 2012
Another woulda/coulda/shoulda for the Washington Wizards against the Cleveland Cavaliers, but what do you expect when Jordan Crawford is the only guard who can make plays? This is the DC Council...
Silver Linings Playbook: Three Positives for the Wizards
►Dan Diamond | Dec 22, 2012
Is there ANYTHING positive to say about these Washington Wizards? Dan Diamond contemplates...
The Bobcats Run Away From Their Past
►Dan Diamond | Nov 24, 2012
Speed is the name of the Bobcats' game now, as they still aim to escape a not-so-good past the the temporary history of Raymond Felton, Stephen Jackson and Gerald Wallace.
Can This Team Win? The Wizards Franchise Optimism Index, Take Two
►Dan Diamond | Oct 30, 2012
Forgive D.C. sports fans for seeming gloomy – for feeling like there's a dark cloud hanging over their heads. Ok, maybe that's just Hurricane Sandy. But after a sunny September that...
#WizardsRank: Nick Young, No. 13: Smiling Through the Tears
►Dan Diamond | Oct 1, 2012
Truth About It.net will turn a whole five years old at the end of this October. Hard to believe/interesting. Nonetheless, over the life of the site from the 2007-08 season to...
Should the Wizards Amnesty Andray Blatche?
►Dan Diamond | Jul 12, 2012
Within the next six days, we'll find out if 7-Day 'Dray is here to stay. (Well,...
How to Evaluate Every Wizards Trade: WWOKCD?
►Dan Diamond | Jun 21, 2012
A word of warning: I'm Truth About It's resident pessimist. You may remember me...
True or False: Half of All 7-Footers are in the NBA
►Dan Diamond | May 3, 2012
Roy Hibbert is a very, very tall man....
The Fate of James Harden's Brain and Ron Artest's Season
►Dan Diamond | Apr 23, 2012
An intense game between two Western Conference powers. A hard smack...
Memo From TAI Readers: How to Fix the Wizards
►Dan Diamond | Apr 4, 2012
The Wizards stink. And that isn't my grumpy reaction. It's a sad, embarrassing fact. In today's Washington Post, Michael Lee warned that the...
Memo to NBA: Contract the Wizards
►Dan Diamond | Mar 27, 2012
Sacramento. Golden State. Detroit. Everyone beats the Wiz. So I say—let's join 'em. Break them up. Dismantle the court. Burn the uniforms. Make the Wizards...
Paul Pierce: One of The 5 Greatest Draft Steals Ever?
►Dan Diamond | Mar 25, 2012
When the Wizards have the 10th pick in the NBA Draft, we get a player like … Jarvis Hayes....
Nene Hilario, JaVale McGee, and the Pareto principle
►Dan Diamond | Mar 16, 2012
JaVale and Nick Young go. Nene arrives. Economist Tyler Cowen said in five words what I'm going to say...


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Kentucky junior infielder J.T. Riddle has been picked in the 13th round of the 2013 MLB Draft by the Miami Marlins, going No. 382 overall, it was announced on Saturday afternoon from the MLB Network Studios in Secaucus, N.J.
Click here for the original story.
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By: hitman201
If this game was release in 2002 or earlier. Then it would have gotten a better score since this was a budget game
Views: 1,756 | Posted: 05/25/2011
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Full title: "Why You Should Not Play: Made Man (Addendum)". A follow-up to the review I made about a month after the original review. Basically me proving points and arguments mentioned about the first video. Plus it shows off the style I wanted to go with the series, had I not been giddy like a kid who gets his long-awaited sweetened food of choice and rushed through it.
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Made Man - Launch-Trailer
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Made Man Demo Gameplay
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Full title: "Why You Should Not Play Made Man (demo)" Something I did to commemorate getting Fraps to work. Done in about a day. I found this demo after being pointed out to the review of the game by Alex Navarro at GameSpot.com. Boy, this game is horrible. Trust me.
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Week of
Oct. 11
PS4, Xbox One, PC, Xbox 360, PS3, 3DS
Release Date: 10/13/2015
The monsters of R.L. Stine's popular book series are back to haunt in game form.
PS4, Xbox One, PC
Release Date: 10/13/2015
PC, Xbox One, PS4
Release Date: 10/13/2015