text:
Nicotine Treatment of Cognitive Decline in Down Syndrome
This study is currently recruiting participants. (see Contacts and Locations)
Verified December 2013 by Vanderbilt University
Vanderbilt University
Information provided by (Responsible Party):
Paul Newhouse, Vanderbilt University
ClinicalTrials.gov Identifier:
First received: January 25, 2013
Last updated: December 16, 2013
Last verified: December 2013
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study is currently recruiting participants.
|Estimated Study Completion Date:
|March 2014
|Estimated Primary Completion Date:
|March 2014 (Final data collection date for primary outcome measure)


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Find out what your kids are learning, data on local schools and services to support young children.
Entry Codes, Exit Codes, and Enrollment for SY 2014-15
Primary tabs
Last Date:
Online Webinar
OSSE will host webinars on updated entry codes, exit codes, and guidance for enrolling students in alignment with the DCMR's six stages of enrollment, which were last updated on January 10, 2014. All LEAs must record these stages of enrollment for all students in the 2014-2015 school year. This training will also be held on July 24 from 2-3pm and July 29 from 10-11am.
Sarah Sherman
Email: firstname.lastname@example.com
(202) 304-4192

subset: commoncrawl


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The Black Sheep Wins an Elby
It's always nice to see the little guys win big awards, especially if they are local and the Black Sheep, a little place if there ever was one, won the award for Best Neighborhood Restaurant. This place puts a lie to the business adage, "Location, location, location". Even though they are hard to find and parking is scant, they keep packing them in. Congratulations to the owners and thanks to Epicuriousity for posting the winners.
Lemaire at the Jefferson also won an award for Fine Dining.


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Pronunciation: /ˈkaməˌlät/
Definition of Camelot in English:
1.1 (as noun a Camelot) A place associated with glittering romance and optimism.
Example sentences
- His death in 1631 marked the end of this glittering Italian Camelot.
- The Camelots of higher education and cinema studies are repeatedly pelted by a wide, devious variety of assault weapons: distance learning, work speed-ups, part-timer labor, budget cutbacks.
- All we have are the myths, the images, their particular Camelots that say particular things about our two countries.
Words that rhyme with Camelotpolyglot • ocelot
Definition of Camelot in:
- British & World English dictionary
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Celebrate the many years you'll share together with this diamond wedding band in 14 karat white gold. Seventeen sparkling round diamonds, at approximately .25 carat total weight, are set in 14 karat white gold. This lovely ring will represent the never-ending love you share.Item Number: 41040981
Order now for delivery on or before
Monday, October 19, 2015
using FedEx 2nd Day.


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Company Setup
Turkey's social, economic and legislative environment is in such progress to align with the EU that also offers an advantageous business environment.Read more »
Legal Services
Investing or doing business in Turkey involves also legal issues which can result in serious legal problems. ABC Consultancy assists foreign corporations / investors in the field of business that is required.Read more »
Merger & Acquisition
Most executives go into a Merger and Acquisition deal confident they'll be successful. But research tells a different story. About half of acquisitions, mergers and divestitures fails, rather than build shareholder value. Apply for a successful deal?Read more »


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December 2005 Articles & Features
Although many of their vehicles are made here, the import nameplates bring a tidal wave of new technology to U.S. shores for 2006.
Virtually all of the import automakers will bring out significant new 2006 models, among them a couple of hybrids. They also are well into such domestic service technologies as the generic reprogramming of on-board computers under the SAE J2534 standard, with Honda, Nissan and Toyota joining Mazda and BMW with web access for this function. Our tech spyglass is fixed on the near horizon (and a little farther out in a couple of cases); turn the page to see what we see.
It's a big year for Lexus. The GS and IS series are all-new, and there's a hybrid version of the Lexus RX called the 400h. Major changes in the Toyota lineup are a new Avalon and the Highlander hybrid, lower-priced cousin of the Lexus RX.
The Lexus GS and IS and Toyota Avalon share a basic new V6, which is available in 2.5 and 3.5L displacements for the IS 250 and IS 350 sports sedans, 3.0L for the GS 300 and 3.5L for the Avalon. They all have variable intake and exhaust valve timing, but as you'd expect from Toyota , there are differences among them aside from displacement and valvetrain.
The GS is the basic vehicle platform, and gets the 3.0 V6 and the same 4.3 V8 used in the LS (and a hybrid version of the 3.0 V6 coming next year). The IS, with its 2.5 and 3.5 V6s, is a much-modified, more compact version of the GS.
The base V6 for all vehicles has a two-piece cylinder head�the main casting and a separate camshaft housing. It simplifies manufacturing, lowers weight and makes service easier, too. The block is an open-deck design with a DuPont plastic spacer shaped to direct coolant flow precisely for more uniform cylinder temperatures. This reduces engine friction, producing a 1% fuel economy benefit, according to Toyota .
The oil filter is a cartridge type. If you unthread the cap four turns on 2WD models, the oil will drain neatly from it. AWD is available with the 2.5L V6, and on that model, you remove a bolt and insert a drain pipe to do the job.
Now for those fuel injection systems. Avalon has conventional port injection. Its 3.5 V6 produces 268 hp (76.6 per liter). The IS 2.5 and GS 3.0 V6s have direct injection into the cylinders and develop 204 and 245 hp, respectively�in each case, exactly 81.6 per liter. The IS 3.5 V6 has two systems in one engine: direct injection and port injection, producing the highest output�306 horses (87.4 hp per liter).
Direct injection requires a second, high-pressure fuel pump (up to 2000 psi), but helps with performance, emissions and fuel economy. Adding port fuel to the IS 3.5 creates a fuel-mixing strategy that permits elimination of restrictions posed by an intake manifold tuning valve and charge motion valves in the manifold ports. With these air induction parts eliminated, there's more airflow, therefore more power. Adding port fuel also obviates the need for a cold-start injector.
In the sad news department, the automatic transmission dipstick has been dropped from the A960E six-speed, the box used with the 2WD GS and IS V6. The check & fill procedure is lengthy. This transmission plus the others in the GS and IS require a new "WS†transmission fluid, low-viscosity for fuel economy. Use another fluid in "extremely low temperatures,†Toyota warns, and the transmission may not engage.
Like BMW, Lexus also has a variable ratio ("activeâ€) steering system�in the GS 430 (V8). It's part of Vehicle Dynamics Integrated Management, which integrates steering, suspension, brakes and throttle to improve handling. Other Lexus models also have VDIM, but without the variable ratio steering system.
When the driver turns the steering wheel, he actually turns the "stator†of a computer-controlled electric motor. At the end of the stator is an internal tooth ring gear. The rotor of that same electric motor has an elliptical camlike member with a flexible gear that's attached to the steering gear shaft. That flex gear meshes with the stator gear and deforms when turned by the "cam,†so that its position changes relative to the "stator†gear (that's how the variable ratio is produced). Because that flexible gear is connected to the shaft of the rack & pinion steering gearbox, the movement of the output shaft to the steering gear�controlled by a computer�can vary from the movement of the steering wheel, up to perhaps 5°. As a safety backup, the limit is set by a locking device.
The RX 400h and its cousin, the Toyota Highlander, are Toyota 's first "performance†hybrids. That is, although they have the 208-hp 3.3L V6, they get slightly better mileage than a nonhybrid. But the big plus is the acceleration boost that comes from the electric motor assist. The optional AWD system requires an additional electric motor, which is located at the rear axle.
Coming in the spring of 2006 from Toyota is the Yaris, an econocar hatchback that replaces the Echo. It's pretty basic stuff: a 12 1 /2-ft.-long car with the Toyota 1.5L Four that develops 106 hp. There's a five-speed manual transmission and a four-speed automatic. The suspension is MacPherson struts with coils in front and a twist beam with coils in the rear.
There are two new Mazdas for 2006. One is the MX-5, a.k.a. Miata, the two-seat convertible sports car that's all-new, and a benchmark-setter for a rigid convertible. It has a 2.0L version of the Mazda 2.3L Four that's used in other Mazdas and many Ford products. The 2.0 Four (which replaces the 1.8L version) has variable intake valve timing and develops 170 hp, a big boost from the 142 horses of the 2005 model. There's a choice of a five- or six-speed manual transmission, or a six-speed automatic.
The new MX-5 makes extensive use of aluminum and high-strength steel, and gets a plastic intake manifold to replace the aluminum casting.
The underhood layout is a mixed bag. Lift off a plastic snap-in cover and the plugs and injectors are wide open. Although the coolant reservoir and air cleaner are between the engine and radiator, they come out in reasonable fashion. And until you get them out (perhaps the battery, too), you can't get to the radiator or hoses�or even see them�unless the car is up on a lift. Want a look at the condenser? Peer through the grille; it's deeply recessed.
A major service issue is that there's no spare tire. Like some European cars, Mazda saved weight with just a small air compressor and sealer kit, which won't seal large punctures, of course. Run-flats are optional, but if they fail, a replacement probably won't be in stock. With all the run-flats coming into use, this is a problem for shops that do road service.
Mazda also introduced the Mazda5 for 2006, a compact vehicle based on the Mazda3, and which has a 157-hp version of the 2.3 Four. The Mazda5 has three two-seat rows, sliding side doors in the rear and a tailgate, so "compact minivan†isn't an inaccurate description. However, it's designed for handling, a Mazda strong point.
Hyundai certainly has garnered respect with a high-quality product, and even if its cars are not dramatically styled, they look clean and modern. It's the fourth best-selling import nameplate, and by the end of next year, half its cars will be made in the U.S.
Engineering is up-to-date. The 2.4L dual overhead-cam 4-cylinder is the first application of a "world†engine that also will be used by Chrysler and Mitsubishi. And although each maker does its own calibrations, the engine itself was designed by Hyundai. As used by Hyundai, it has variable intake valve timing and mass airflow sensing (vs. speed density on the forthcoming Neon replacement, the Dodge Caliber). It's rated at 162 hp and meets ULEV emissions requirements. Engine mounts are hydraulic, to improve idle smoothness.
The optional 3.3 DOHC V6 also is a new engine with variable intake valve timing. It develops a competitive 235 hp, but also meets level 2 ULEV standards, just like Camry and Accord.
There's a five-speed manual and four-speed automatic available with the 2.4 Four, and a five-speed automatic with the V6.
The front suspension is the double-wishbone type and the rear is a multilink independent. Six air bags (plus active front seat head restraints), electronic stability control, traction control and ABS all are standard�not bad for a car with a base price of under 18 grand.
The new Infiniti M35/45, a luxury sports sedan, uses two well-proved engines: a 280-hp, 3.5 V6 and a 335-horse, 4.5 V8. Although Nissan gets great handling from its ultra-rigid chassis designs, these Ms also have an electronically controlled actuator to adjust rear toe angle by moving the lower links to improve cornering, plus hardware adapted from the G35 series.
The express-open/close door windows and the sunroof both are part of body computer circuits that can be temporarily disabled if the battery cable is disconnected, if a fuse blows or if parts are replaced. In fact, the sunroof may misbehave if the antipinch function is operated for more than five seconds continuously.
Fortunately, both systems can be reinitialized without a scan tool. Turn on the ignition, lower the window to halfway with the manual switch, then close it and hold the switch up for four seconds. With the sunroof, press the Close switch as often as necessary until the sunroof is fully closed and hold the switch in the Close position for four seconds.
The M comes with a mechanical key, but it's strictly for the doors and trunk in case of battery failure of the I-Key (for "intelligentâ€). If that I-Key's battery dies, you won't be able to start the engine with the "key†sitting in the cupholder. However, insert the key into a port to the left of the steering column, then push the Start button.
Nissan will be introducing the 2007 Versa econocar next spring. It's significantly larger and almost 2 ft. longer and more powerful than the competition, Toyota Yaris (formerly the Echo). A 120-hp, 1.8L version of a new 4-cylinder engine will be the powerplant. Despite a sub-Sentra price point ($12,000 base, but more than Yaris), it will offer a six-speed manual, four-speed automatic or a version of the continuously variable transmission (CVT) that has been so successful in the Murano. Nissan is betting big on CVTs, promising that 40% of the cars it sells will have them by 2007. It's one of the keys to high fuel economy for the Versa, which reportedly will have a combined city/highway average of 38 mpg. A front-to-rear group of other technologies also contribute to the high fuel economy. Although it has a MacPherson strut front suspension and twist beam rear, the Versa also has an interior that says "not cheap.†A hatch will come first, a sedan later.
The Subaru B-9 Tribeca is based on the Outback wagon, and uses the 250-hp version of the 6-cylinder boxer engine. It gets a 3-in. increase in wheelbase (to 108.2 in.), just a 1-in. increase in overall length (to 189.8 in.), but a 5-in. increase in height (to 66.5 in.). The tall-box approach provides room for the optional third row of seats, a competitive necessity in today's market. Naturally, it has all-wheel-drive (55% power to the rear wheels). But with a planetary gear center differential and electronically controlled hydraulic clutch, the power goes where needed. It's combined with Vehicle Dynamics Control, a yaw-sensing electronic stability system.
The result is a roomy package with good handling. The boxer engine sits low, which contributes to a lower center of gravity. The vehicle is a five-star crash performer in front and side impacts, and there's an M-shaped structure in the rear underbody to improve rear safety.
There's an all-new Civic line�sedan, coupe, Si coupe and hybrid sedan. With yearly Civic sales over 300,000, you can expect to see plenty of these requiring future maintenance.
The hybrid got an extremely clever reengineering, so that without a real change in the configuration, it goes from merely an acceleration assist to the ability to operate the car on electricity alone in slow-moving traffic. Here's how: All four cylinders are deactivated�a reversal of the conventional variable valve lift system. With all the valves closed, the engine would normally stop. However, the crankshaft is connected to the electric motor, so instead of an assist, the motor both moves the car and keeps the engine turning. Because the valves are closed, the pistons operate against what is effectively an air spring. The electric motor uses only a bit more power than if the engine were completely separate, as with a Toyota or Ford Escape hybrid.
The new system did require engine modification�a second oil control valve for the deactivation of all four cylinders. It's really just a backup, because three cylinders were disabled on deceleration in 2005 models with a single valve. However, there's an oil control valve failure mode that could have prevented the 2005 engine from coming off idle if all four cylinders became disabled. Keeping one cylinder alive on the 2005 hybrid was a fail-safe, enabling the car to move a bit, such as off to the shoulder.
Honda also added a third stage to the 2006 valve lift system, to improve high-rpm performance. The engine is rated at 93 hp, up from 85 in 2005.
The 2006 electric motor is more powerful�up from about 13 to 20 hp. That's enough for low-speed operation without a big boost in the capacity of the battery pack. It's up from 144 to 158 volts, but that's basically just what Honda calls "continuous improvement.†The new system provides a 10% improvement in gas mileage (from about 45 to 50 mpg). The system is lower cost than those with higher voltage battery packs but has more complex electronics than the Toyota and Ford systems.
The regenerative braking system is up a huge 170%, thanks to a computer control that proportions more braking to the regen setup than to the friction brakes. Some of the gas mileage increase may come from making standard the CVT that's optional on other Civic sedans.
As for the nonhybrid Civics, the sedan and coupe get a 140-hp version of the single OHC 1.8L Four. It has a two-stage lift control and two-stage plastic intake manifold. The Si coupe has a 197-hp edition of a 2.0L version of the SOHC four�98.5 hp per liter, naturally aspirated. Horsepower peaks at 7800 and 139 ft.-lbs. of torque at 6200, so this is an engine to rev. The six-speed manual with short-throw shifting makes it fun.
The transverse front-drive A3 is Audi's newest entry into the U.S. market. It's short�14 ft.�and is powered by a 2.0L direct-injection four, but turbocharged to produce 200 hp and still get decent gas mileage. For extra performance, the 250-horse, 3.2L V6 is an option, and quattro all-wheel-drive is available.
The A3 is the first U.S. entry with a dual-clutch "automatic†transmission, something you'll be seeing from other European manufacturers. It's basically two automatically controlled manual-type transmissions in a single housing, one transmission above the other, with each one controlled by a multidisc clutch. The two clutches are positioned one ahead of the other, each on its own shaft, with one shaft hollow so the other can pass through. One shaft has the odd-number gears and Reverse, the other the even numbers. The gears on each input shaft mesh with the gears on the appropriate output shaft. A hydraulic valve body with electronically controlled solenoids executes the shifts by engaging the appropriate gear on one output shaft at a time.
The upshift or downshift is made while the transmission is engaged in the previous gear, and it's completed when the computer disengages one multidisc clutch and engages the other. Clutch operation is carefully modulated so the shifts are smooth, and the power transfer from engine through transmission is almost continuous, improving acceleration. The clutches (in a fluid-filled housing) help provide a reported 15% better fuel economy than a torque converter, and their modulated engagement actually dampens engine pulses better at low rpm.
A new VW Jetta joins the new Golf for 2006. A key change is a 150-hp, 2.5L 5-cylinder engine, replacing the 115-hp, 2.0L 4-cylinder. It's offered with six-speed manual or automatic transmission now; the dual-clutch box is coming late in the model year.
The new transverse front-drive Passat is being introduced with the same 2.0L direct-injection Four turbo used in the Audi A3. But soon there'll be available a 280-hp, 3.6L version of the ultra-compact narrow-V6�the engine with a bank angle of only 10.6° (vs. the usual 60° or 90°), and a single cylinder head. The six-speed automatic is standard, and a dual-clutch box is in the future plans for this model, too. Front suspension still is MacPherson strut, with a multilink setup for the rear.
The new 3-Series is longer and wider, of course, but not by much (up 2 in. to 178 long and up 3 in. to 71.5 wide). Engine performance is up, as the base in-line 6-cylinder engine has been enlarged from 2.5 to 3.0 liters. But it's not just using the longer stroke of the 3.0 in the 330 models. BMW has all-new I-6 engines and some of the technology is gee-whiz. The base engine produces 215 hp, the uplevel powerplant 255 ponies. There's also a special "performance†engine that produces only 235 hp but has a different torque curve and slightly higher peak torque.
The block exterior of the engine is magnesium and the interior (cylinders, coolant passages, etc.) are an aluminum insert. The hot magnesium casting sort of shrink-fits onto the aluminum interior casting, with each locking to the other with special ribs. The magnesium bedplate holds a steel main bearing halves insert. The cylinder head is aluminum and the camshaft cover is magnesium. With all that various metallurgy, you shouldn't be surprised by the fact that there are special (blue tint) aluminum engine bolts that are not reusable.
The old two-belt accessory drive is gone, thanks in part to an electric drive for the water pump. There's a single serpentine belt and the engine is an inch shorter as a result.
The new engines adopt BMW's infinitely variable intake and exhaust valve lift and timing control from the V8s. The variable lift system uses finger-type rocker arms instead of bucket hydraulic lifters (as on the old I-6) and a servo motor-controlled eccentric shaft with cam followers.
The front suspension uses two lower arms in combination with a coil spring strut, a design adapted from the 5-Series and higher models. The rear suspension is a five-link design. The active steering in the 5- and 6-Series models is an option. This design uses a computer-controlled planetary gear system called "variable ratio,†but actually is a partial steer-by-wire system. The range is just a few degrees (as on the Lexus GS).
The brakes also have a "mind†of their own. The windshield rain sensor sends a signal to the ABS, which operates a "kiss†mode to wipe water off the discs and pads. The brakes don't actually engage, but it's enough to dry them off.
The Eclipse sporty coupe is a model that Mitsubishi has always been able to sell, along with the pocket rocket called the Lancer Evolution. The 2006 version is a beautiful car, and the 2.4L 4-cylinder, rated at 162 hp, performs well. The vehicle is based on the Galant platform, so yes, the 3.8L V6 also fits in. In fact, there's a 263-hp version (variable valve timing and lift) available on the GT. However, you'll generally see the 2.4 Four, and�surprise!�it has a split exhaust system with separate catalytic converters and oxygen sensors. The transmission choices are five-speed manual or four-speed automatic.
Here's something hard to believe: A Mercedes is getting lighter. The M-Class for 2006 is down 400 lbs. to 4623 with the V6, despite a lengthening (6 in., to 188 overall) and widening (3 in., to 75.2). No diet; the M-Class simply was taken off its separate truck-type frame and built on a unibody. The 3.5L, 24-valve V6 is rated at 268 hp, the 5.0L V8 (three valves, two plugs per cylinder) at 302 hp.
Air suspension (with a 3-in. upward range) is an option. The M-Class continues to use a 50/50 front-rear split open center differential with ABS for its all-wheel-drive system.
The DOHC 3.5 V6, introduced in 2004 on the 2005 SLK, is being phased in on all V6 models. It has variable intake and exhaust valve timing and a broad torque curve (87% available from 1500 rpm to the 258 ft.-lbs. peak at 5000). The intake manifold is magnesium and has two-stage flow paths and charge motion valves ("tumble flapsâ€) for increased turbulence at part-throttle, to improve air/fuel mixing.
The transmission is Mercedes' league-leading seven-speed automatic, which can skip through more than one gear on downshift acceleration, such as from 6th to 2nd gear.
Surprisingly, the new M-Class has only two seating rows, to create a roomier package for four to five passengers. Why not a third row? Because Mercedes also introduced the R-Class, which is a price class upscale (about 8 to 10 grand more) and which has that third row.
The R-Class is a foot longer but weighs only 140 lbs. more, and has the same engines and drivetrain, including the seven-speed automatic and AWD, and optional air suspension. On this model the shift lever is nearly invisible�just a small electronic stalk on the right side of the steering wheel�up for Reverse, down for Drive, plus manual shift buttons on the steering wheel.


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mocha brown colorblock leather 'Muse Two' satchel
designer's notes
Versatile and ladylike, the 'Muse Two' satchel from Yves Saint Laurent elevates every outfit to a new level of luxury.
color: Mocha (Brown) / Black / Purple Supple, pebbled calfskin leather with canvas insets along edges and antiqued goldtone hardware Front flap with pin closure and pin-close patent leather straps at front sides Triple pin closure at rear slip pocket 14'' long patent leather top handle with 6'' drop Canvas lining with expandable compartments and center zip compartment Five protective metal feet at base with welt seam detailing Measures approximately 12'' at widest x 9'' tall at center x 6'' deep; weighs 3 lbs. Leather; Italy; style# 317871601


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Training Tips
You'll get the maximum amount of enjoyment out of your hiking trip if you are physically well-prepared for it. We recommend hiking, swimming, running or other aerobic activity combined with strength exercises and stretching for optimum preparation. We offer the exercise regimen below as a guide to help you prepare.
Please note: it's very important to adapt this plan to fit your specific circumstances and goals, as well as the specific demands of the trip you're joining. We also recommend checking with your doctor before beginning a new workout routine. Feel free to email us or call us at 800-715-HIKE (4453) with questions.
Engage in a routine of three 45-60 minute workouts per week. Workouts can mix cardio (running, climbing stairs, swimming, cycling..etc.) with strength exercises. The Stairmaster machine, with revolving stairs like an escalator, is excellent for preparing for a hiking trip.
One day per week do an extended cardiovascular workout. Long hikes on hilly or mountainous terrain are best as they well-replicate what you're preparing for. Cycling, swimming, playing sports, or combinations of these activities, also work well. Four to six hour workouts are best.
If you're joining a backpacking trip, we recommend putting 25-30 pounds of weight into a backpack and hiking with it during your longer, once-per-week workouts. The hillier the terrain, the better.
Stretch before and after workouts for 5-10 minutes. Be sure and stretch all of your major leg muscles, your shoulders, and your back muscles.
Drink plenty of fluids, 3-5 liters of water and juice per day depending on your body weight.
Eat a well-balanced diet with lots of fruits and vegetables. Avoid highly processed or sugary foods and drinks.
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Hearing Protection
8 Results Found that Include 18 Products
- Disposable Ear Plugs, CordedDisposable Ear Plugs, Corded
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Wear these ear plugs for the day, and toss them out when you're done. The attached cord helps you keep track of your plugs and prevent loss. Self-adjusting foam plugs...More
Price $82.45 - $89.20
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Ear plug dispensers are the most convenient way to make hearing protection available to your workers, and these dispenser-ready refills are an economical way to keep...More
Price $80.00 - $83.70
- Reusable Ear Plugs, CordedReusable Ear Plugs, Corded
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Here's a simple, affordable solution for hearing protection: reusable ear plugs only need to be replaced every 3-6 months, while the attached cord helps prevent loss....More
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- Ear Plugs, 29dB, W/o Cord, Univ, PK100Disposable Ear Plugs
- Item # 3NHA5
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- Headband Ear Muffs, Gray/Black, NRR 25 dBElectronic Ear Muff
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Catalog Page # NA
- Power Pack ChargerPower Pack Charger
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- Vehicle ChargerVehicle Charger
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May we suggest
The faceted wood featured in our Windsor Bedroom Set makes this a fascinating way to furnish your sleeping space. Made in Malaysia with both solid with and plywood, this 5-piece set includes a queen or king-sized bed, 9-drawer dresser with attachable mirror, and two 3-drawer nightstands (the chest of drawers is not included and is not sold separately). A cherry-tinged brown stain is a lovely neutral tone and is accented with dark brown faux leather on the headboard and brushed silver-colored metal drawer pulls. The Windsor Designer Bedroom Set requires assembly and should be dusted with a dry cloth. A queen-sized version of this set is also available (sold separately).
- Contemporary bedroom set
- 5 pieces: 1 queen or 1 king bed, 1 dresser, 1 attachable mirror, 2 nightstands (chest not included and is not offered separately)
- Solid wood and plywood frame with cherry-tinged brown finish
- Dark brown faux leather with polyurethane foam padding (headboard)
- Brushed silver-colored metal drawer pulls
- Made in Malaysia
- Wipe clean with a dry cloth
- Assembly required
- Mattress and box spring required (not included)
- Available with a queen bed or a king bed (sold separately)


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Junior sees future in student affairs
Wimer Alberto loves a challenge.
He's an orientation advisor, a resident assistant in Newing College, a member of the Latin American Student Union and a dancer with the campus group Quimbamba. He also loves to DJ parties, go to the movies and write songs and poetry. This fall, he'll be a REACH peer educator in addition to working at Audiovisual Services.
"I learned from the RA job how to manage my time," said Alberto, a junior. "You make use of the time you have in between things."
Marinda Souva, assistant director of Campus Life for new student programs, said Alberto balances his time well and gives 100 percent to the groups and jobs he takes on. "He's very conscious of his time, and he makes sure he follows through on his commitments," she said.
Alberto, who's double majoring in sociology and English, hopes to pursue a career in student affairs. His favorite writers include Voltaire and Dostoevsky.
"I like things that are really dense," said Alberto, 20, who was born in the Dominican Republic, but grew up in the Bronx. "I like to get challenged."
Souva said Alberto is mature, self-confident and fun to work with. "He leads by example," she said. "He has an extra level of understanding of what it means to project yourself professionally."
Alberto said Binghamton was the first campus he visited and remained his first choice even when he was admitted to several prestigious liberal arts colleges. He still remembers calling a cousin from the Events Center and telling him that this is where he was going to go to school.
Alberto believes Binghamton, with an undergraduate enrollment of a bit more than 14,000, is the perfect size.
"The school is big enough that you don't know everyone and small enough that you still get personal attention," he said. "There's always someone new for you to meet."


text:
Big Coal shaping Public School education–really!
This cartoon was inspired by the Washington Post article, "Energy industry shapes lessons in public schools"
Big Coal may be molding our youth with pro-coal propaganda, but worry not, Big Coal also offers a "green" video to teachers called "The Greening of Planet Earth," which says that "our world is deficient in carbon dioxide, and a doubling of atmospheric CO2 is very beneficial."
Doubling the CO2 is good for you. By you they mean their bottom line. Afterall, to Big Coal "you" are either a means to drive profit or block profit. They're doing what they can to make sure our children do not grow up and do the latter. Of course, they're also making sure our children grow up with an increased risk of asthma, premature death, and mercury-related illness.
Fortunately, the EPA just set new rules to limit mercury and other toxic emissions. As David Roberts of Grist states, "It will save tens of thousands of lives every year and prevent birth defects, learning disabilities, and respiratory diseases. It will make America a more decent, just, and humane place to live."
David, and EPA Administrator Lisa Jackson, must not have gone to a Coalementary School. However, these folks did!
Joe's cartoon archive, twitter ramblings and StumbleUpon page…
Incorrect source, offensive, or found a typo? Email us (please put title in subject bar of email so we'll be able to fix). Or do you want to write for Elephant?
{Waylon H. Lewis C Enterprises 2015: Use Rights in perpetuity. Ownership remains with author.}
One Response to "Big Coal shaping Public School education–really!"
Now, I'm not saying this about home birth, but I REALLY hope you find a GYN you are comfortable with and whom you can trust. Not for your birth issues, but because I believe every woman needs and deserves someone they can go to with their most personal problems without fear or judgment or embarrassment.


text:
- Northern New York Newspapers
- Watertown
- Ogdensburg
- Massena-Potsdam
- Lowville
- Carthage
- Malone
- NNY Business
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COLTON - The next performance in the summer series of Colton Riverside Gazebo Performancesfrom 6:30 - 8:30 p.m. Aug. 22 features the Riverside Brass Quintet.
The quintet was formed in 2009 and consists of highly experienced players who all have connections to SUNY Potsdams Crane School of Music. The members of the quintet are trumpeters John Schorge and Paul Buell, trombonist Peter McCoy, tubist Peter Popiel and Roy Schaberg on the French horn.
The group will perform a variety of music chosen for wide audience appeal as well as high musical quality.
The performances, weather permitting, are held at the Gazebo behind the Museum at 95 Main Street in the hamlet of Colton overlooking the Raquette River. The Museum is located next to the Zion Episcopal Church and across the street from the Town Office. The rain location is the towns large covered Pavilion on Sugar Bush Lane in the hamlet of South Colton next to Swift Field. Signs will be posted if the performance is moved from the Gazebo to the Pavilion.
Audience participants should bring their own chairs or blankets for sitting on the lawn in front of the Gazebo (or on the concrete floor in the Pavilion if moved). Volunteers will be on hand to assist people if desired.
Before and during the performance, the Colts Pride Booster Club will have hamburgers, hot dogs, drinks and other food available at very reasonable prices. Purchases of food and drinks support extracurricular activities at Colton-Pierrepont Central School. Bathroom facilities also will be open to the public.
There is no charge to attend the Gazebo Performances showcasing singers and musicians from places along the Raquette River as the series is made possible, in part, with public funds from the New York state Council on the Arts Decentralization Program administered in Jefferson, Lewis, and St. Lawrence counties by the St. Lawrence County Arts Council.
A special drawing of artwork featuring the Gazebo by local artist Judy Filarecki is held during each performance to help cover the towns share of the expenses; and donations also are accepted.
The towns Tourism & Beautification Committee also will have a table set up with Colton shirts available to purchase as well as the towns new tourism map, notecards of things to do and places to see in town all seasons of the year, and possibly more. Purchases of products support various town-related activities.
The final performance in the summer series of Colton Riverside Gazebo Performances is rescheduled from earlier this summer.
The Fat River Kings, based out of Long Lake, will perform at 6:30 p.m. Sept. 1.
More information about performances and other activities is available on the town website (www.townofcolton.com) and from town tourism and beautification coordinator Ruth McWilliams (315-262-2450; firstname.lastname@example.com).
Thousands of readers like you have made Northern New York Newspapers the number one ranked website* for local news and sports coverage in the north country.
You can continue on to this article in a few seconds, or you can visit one of our websites:


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Events in the Persian Gulf
Iraq's ambassador to the U.S. discussed recent events in the Persian Gulf including today's announcement by Saddam Hussein that all hostages held in Iraq will be released unharmed.
People in this video
- Mohamed Sadeg al-Mashat Ambassador Iraq->United States
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The ambassador explained the Iraqi perspective on the events in the Middle East.
U.S. Persian Gulf Policy
Sen. Kassebaum, a member of the Senate Foreign Relations Committee, discussed recent events in the Persian Gulf.
U.S. Persian Gulf Policy
Rep. Hefley, a member of the House Armed Services Committee, discussed U.S. policy in the Persian Gulf.


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Cushion cover in glossy velour with a burnout pattern and concealed zip. Size 20 x 20 in.
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Bitter Sweet Eating Dem Teal T-Shirt
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Buy1 Get1 Free
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Awe, look, your monster buddy made you cupcakes.
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Frank Rose, Tria Wood and John DeMers are the movers and shakers responsible for ArtsHouston Magazine. the discuss their venture and the Houston arts scene with TFR host Dean Dalton. ξξListenξ Downloadξξξ
Choreographer Michele Brangwen stops into the KUHFξPerformance Studio along with bassist THomas Helton and members of the Danielle Reigh Trio. They preview the upcoming performances by the Michele BrangwenξDance Ensemble.ξξξListenξ Downloadξξ
KUHF's Chris Johnsonξtalks with Rebecca Green Udden of Houston's MainξStreet Theaterξabout the current production of Keith Bunin's The Busy World is Hused. It's a regional premiere and the season opening production for the company andξis on-stage throughξOctober 21st. ξListenξ Downloadξξ


text:
David H. Ellison, M.D.
Professor of Medicine
Division of Nephrology & Hypertension
OHSU and Staff Physician VAMC
Lab members
Back to faculty page
Human blood pressure is maintained within a narrow range, despite wide variation in dietary behavior. Hypertension, the most lethal disease in the world, results when the homeostatic systems maintaining control fail, in the setting of environmental challenge. Kidneys play a surprisingly central role in these processes by adjusting salt and water excretion to meet demand. The Human Hypertension Laboratories at OHSU work to unravel mechanisms underlying normal blood pressure homeostasis, and the causes of homeostatic failure. We also work to develop novel approaches to address existing hypertension, both with lifestyle changes and novel drugs. The program comprises the Ellison Laboratory, the McCormick Laboratory, and the Rozansky Laboratory. We investigate mechanisms by which the kidneys regulate blood pressure using molecular and transgenic techniques aimed at identifying novel hemodynamic pathways. We focus on major salt transport proteins in the kidney, including the thiazide-sensitive Na-Cl cotransporter (SLC12A3) and the bumetanide-sensitive Na-K-Cl cotransporter (SLC12A1). Mutations of these genes cause salt wasting disorders in people. We also investigate how mutations in genes that regulate these transport proteins cause inherited hypertension. One such disease is familial hyperkalemic hypertension (also called pseudohypoaldosteronism type 2 or Gordon's syndrome), which can result from mutations in a novel group of kinases known as WNKs. It can also result from mutations in members of the cullin Ring E3 ubiquitin ligase pathway. Our laboratories are elucidating mechanisms involved, using techniques that range from biochemical, to knockout model development, to human investigation.
We are also interested in translating insights gained from careful assessment of human disease back to the laboratory, to develop novel approaches to improve patient care. We noted many years ago that the combination antibiotic, trimethoprim-sulfamethoxazole (Bactrim, Septra) caused hyperkalemia in patients; we used animal models to prove that this phenomenon was the result of trimethoprim blacking sodium channels in the kidney. This insight changed clinical practice. More recently, we showed that the immunosuppressive drug tacrolimus causes hyperkalemia and hypertension, in part, by stimulating the thiazide-sensitive Na-Cl cotransporter; clinical trials are now underway testing whether blocking this pathway will ameliorate these complications in organ transplant patients. Finally, our groups have had longstanding interests in how patients become resistant to commonly used diuretic drugs. We are developing models to test how diuretic drugs elicit compensation via regulatory pathways, leading to resistance that might be susceptible to treatment.
Recent Publications (Pub Med)


text:
Event Summary
after a lengthy and painstaking soul-searching exercise, Invensys plc,
the global automation and controls group with headquarters in the UK, created
a new group within its Production Management Division (PMD)
called Invensys Production Solutions (IPS) (www.invensysproductionsolutions.com).
The group will include the PRISM and Protean
process ERP products plus the resources of Invensys Validation Services
group (www.vtc-usa.com),
a Montreal, Canada-based provider of regulatory compliance, validation, and
consulting services encompassing the entire validation project life cycle and
a range of validation services for the regulated supply chain.
While the newly formed unit should have much strength, since the PRISM and Protean products contain functionality that at least challenge the leading products in the process manufacturing arena, it also has liabilities that must be addressed, in a great part because existing users of its above solutions have suffered from frequent product strategy changes as a result of vacillations by the Invensys parent company.
the past three years, Invensys process solutions' customers have experienced
the displeasure of witnessing several radical changes of strategy, causing some
of them to begin to seriously doubt the vendor will ever deliver their market-specific
product capabilities. In July 1999, Invensys bought the outstanding shares of
then struggling Marcam Solutions, and folded it initially into
its Wonderware factory automation division. Further, in August
2000 Invensys acquired then also languishing Baan Co. (see
Yet Another ERP Vendor to Find a Sanctuary Under Invensys' Wing) and made
it a part of the former Invensys Software Systems (ISS) division.
initial strategy for the products, which was announced after the Baan acquisition
was to release a unified Baan product that combined functionality for discrete
and process manufacturing (see Process
ERP Market Loses PRISM and Protean). After hearing existing customers' less-than-pleased
feedback and after another reconsideration of its past investments, Invensys
then modified that strategy to one of creating the Baan Process division (see
Invensys Announces New Division - Baan Process) which included five process
ERP products coming to Invensys through Marcam and Baan acquisitions: Baan IV
Process, Baan Dimensions, PRISM, Protean, and Baan Cable & Wire. The announcement
was a departure from rewriting all the products into one core iBaan ERP product
the unit was not going to provide an integrated solution any longer, but would
rather provide combined applications capabilities via an integration framework.
given Invensys has recently yet again put all its assets/investments under the
magnifying glass, it has now allocated the PRISM and Protean products into their
own profit-based division, called Invensys Production Solutions. Sanjay Razdan
will be the newly formed group leader, and will be responsible for the development,
marketing, sales, and support of the Protean and PRISM process ERP software
solutions and the Invensys Validation Technologies. By joining the Invensys
Validation Technologies group with PRISM and Protean, IPS should be able to
offer enhanced regulatory compliance solutions for the process and regulated
industries. Validation Technologies has been a part of Invensys Pharmaceutical
Solutions, another group within the Production Management Division
of Invensys, and one of the leading suppliers of validation, pharmaceutical,
engineering, and regulatory-compliant solutions. Founded in 1994 and with over
110 dedicated consultants, the group is currently one of the largest suppliers
of regulatory-compliant solutions in North America and Europe, dedicated to
the pharmaceutical, biological, biotechnology, and medical devices industry.
the Baan product line focuses on the discrete and hybrid (with only simple process
requirements) manufacturing sectors, this move should enable both organizations
to fully leverage their strengths in their respective industry sectors. Under
the new setup within Invensys PMD, well over 80% of revenues will now likely
come from process industries, since, in conjunction with solutions provided
by sister Invensys companies such as Wonderware, Avantis, Foxboro,
Eurotherm, APV, and Powerware,
Invensys Production Solutions also provides a broad set of capabilities for
the process sector. Thus, Baan might now be singled out as the possible discrete
manufacturing black sheep' in the family, causing Invensys to likely occasionally
review the carrying value of its investment in Baan. Still, while Invensys does
not plan to integrate iBaan ERP functions with PRISM and Protean, it does plan
to leverage Baan's collaborative supply chain management (SCM) or customer relationship
management (CRM) software, using Baan OpenWorldX enterprise
management level integration framework, which, together with the ArhestrA
framework at the plant automation level and Production Engine (PE)
framework at the production management level, still represents a part-and-parcel
of the Invensys Real Time Enterprise (RTE) framework (formerly
referred to as the "sensor to boardroom" strategy).
is Part One of a two-part note.
Two will address Invensys Liabilities and Strategy and make User Recommendations.
Historic Strengths
company, although constantly morphing from Marcam to IPS, has a good track record
and a heritage of selling solutions to manage divisional or autonomous plant
sites within selected process industries. The products are very strong in plant
level management functionality, given the IPS' progenitor, former Marcam Solutions,
headquartered in Newton, MA, was one of the first global providers of ERP and
enterprise asset management (EAM) software exclusively for process manufacturing
enterprises and large corporate divisions. Marcam Solutions was created after
the 1997 breakup of Marcam Corporation, a company that had
struggled to manage the business of two product lines that targeted the two
completely different markets of discrete and process manufacturing. Namely,
the dissolution of Marcam Corporation had then created two new ERP software
companies, Marcam Solutions and MAPICS Inc. (NASDAQ: MAPX),
the latter of which is still going strong in its original form.
Margolis and John Campbell founded Marcam (a name derived from their last names)
back in 1980 to provide then IBM's MAPICS ERP product installation
and customization services. In 1983 Marcam began developing its own planning
and control software for process manufacturing companies such as food, chemicals,
and pharmaceuticals. The result was PRISM, which was first licensed in 1987.
Marcam went public in 1990 and acquired ShawWare (maintenance
management applications, whose Avantis product is now a part of a different
unit within Invensys) in 1991, and the MAPICS product line from IBM in 1993.
Marcam launched Protean ERP software in 1994, and during 1995, it all but halted
major development of a client/server version of PRISM to focus on its similar
but technologically more advanced and seemingly more prospective Protean line.
PRISM and Protean software suites both automate tasks such as resource planning,
production model development, and quality control management. Marcam sold its
product primarily through its direct sales force in close to 20 offices worldwide.
The Company also partnered with a number of industry-leading vendors including
Hewlett-Packard, NEC (as a reseller and a developer of earlier
versions of Protean in the Japanese market), IBM, and PeopleSoft, to name some.
Marcam Solutions had approached its financial management functional gap by partnering
and offering warranted integration to major financial applications such as SAP
R/3, PeopleSoft and CODA. By 1999,
the Company had approximately 1,400 customer sites in over 40 countries before
it was acquired by Invensys' Wonderware division.
As mentioned earlier, the PRISM product is a veteran of the Process ERP market with many considering it the pioneer in this segment, and it can arguably be called the most widely installed plant-level process ERP product available. The company claims that 100% of its 1,200 sites (i.e., with its own server unit) are running plants with many installations running multiple plants, given these sites originate from little over 600 corporate customers. IPS' management estimates that PRISM currently has over 85,000 users worldwide, out of total 100,000 users for both products together.
boasts deep manufacturing, financial and distribution functionality for process-oriented
manufacturers and the quality advantage of decades of use by customers. However,
its sales order management module has worked well mainly for environments with
medium complexity of order management. PRISM's main liability though is its
reliance on the reliable but lately less trendy IBM AS/400 (now
IBM iServer) platform. The product was written almost completely
in IBM RPG (Report Program Generator) aged language, with only a very limited
number of C++ functions on the client side. Unlike Protean, which was envisioned
as a product of the future and thus had the vast majority of development resources
from its inception, PRISM had only limited enhancements that focused mainly
on customer-requested functional, but not technological, changes in the product.
most significant recent enhancement to PRISM was possibly Y2K compliance in
release 4.3, which shipped way back in 1996. Thus, it continues to have quite
limited success in IBM AS/400-centric process manufacturers and generates the
bulk of its revenue from a large installed base. The large installed base in
turn means that niche vendors with add-on enhancement systems that address the
needs of the process market will have had increased opportunities over the last
several years, and possibly going forward (see Stratyc's
Laser-Sharp Focused Tools Retrofit Legacy Systems and MAPICS
XA Expands BI Offering Through Partnership With Vanguard).
on its hand, claims much of the same functionality as PRISM with some functional
enhancements on UNIX or Microsoft Windows platforms. Its major
modules would be: Production Modeling, Formula Management, Planning and Scheduling,
Inventory Management, Product Costing, Asset Management, Customer Order Management,
Procurement, and Financials. It has a deep functionality for batch-based hybrid
(i.e., both process and some discrete repetitive) manufacturing such as for
food & beverage, pharmaceuticals, and consumer packaged goods (CPG) enterprises,
as well as capabilities for complex process manufacturers requiring some continuous
process capabilities, recycling and recurring materials (e.g., catalysts) and
product characteristics-based planning capability, as in case of some chemical
company's motto has long been that reality that cannot be modeled, cannot be
managed either. To that end, Protean's patented Production Model
was devised to model, plan, cost, and analyze reality. It differs from almost
all other ERP suites that have to tweak bill of material (BOM)-based systems,
by uniquely dealing with process manufacturing realities and by avoiding so
called software "fatal flows" (see What
Makes Process Process? and The
Fatal Flaws for Process Manufacturers) such as:
To that end, with its pivotal module, Production Model, Protean considers both the resources (e.g., primary and secondary materials, electricity, water, etc.) and the processes (e.g., routing steps, machines, labor, etc.) that work together to make a final product, as well as the elements that come out of that production process (e.g., co-products, by-products, waste, etc.), which is in contrast to a standard discrete' BOM recipe-like approach to production. The Production Model enables organizations to define the steps involved in making a product, but at each step, they can identify all the requirements, such as raw materials, water and energy resources, packaging, labor, machines, and all other elements affecting value and cost of the product. This information is then used by Protean in other modules or interfaced applications, including production scheduling, production planning, costing, and analysis, to provide a more accurate picture of the production process and promote better, more-informed business decisions.
Closely related to Production Modeling is the Cost Modeling application, which manages costs (such as fixed/variable overhead rates, co-product and byproduct, and the effect of recycled materials and waste) and margins across the supply chain, and allows users to perform what-if analyses for simulations and analysis for different strategic business scenarios. It also calculates costs of all resources used in the manufacturing process, and identifies the cost elements contributing to total resource cost, using activity-based costing (ABC) principles.
Also a landmark strength of the product is its process industries-oriented purchasing and inventory management, since users can track inventory by special characteristics down to the lot and sub-lot level throughout the life cycle of the product, even for recyclable materials. Also, not many peer products will offer an inventory inquiry capability that allows users to locate data at such a granular levels, as lots and sub-lots can be recorded and tracked with every inventory movement — from vendor receipts or raw material during a production process to the delivery of finished goods. For each lot and sub-lot, the software tracks inventory information, such as quantity, classification, availability, and multiple dates, such as expiration, manufactured, retest, shelf life, and user-defined aging dates (e.g., best sold by, ship-by, etc.). The application can track, move, and control inventory at the unit level (i.e., pallet, drum, slip sheet, etc.), with each unit having a unique system identifier. Multiple unit-of-measure (UOM) quantities are available when potency or catch weight control is required for some industries, resulting in a UOM conversion by lot. Location classifications are also available so that users can create various types of inventory states, such as inventory in quality control, in transit, on the loading docks, etc.
Also impressive is Protean Planning module, whose Quick Scheduler enables organizations to incorporate vital capacity data into the production planning run to shorten and speed planning cycles, since it addresses production resources and capacities in one planning pass. A Power Pegging feature allows organizations to view all demands affected by an interrupted supply or by changing production conditions, while one can view the production status for an order at the customer's request or notify the production floor of the impact when a customer order is canceled or changed.
Protean is used at approximately 250 sites from over 170 corporate customers, since, owing to its originals owner's protracted difficulties in the late 1990s, when Marcam Solutions was only able to close less than dozen Protean deals on a quarterly basis, with most of its revenue coming from the PRISM part of business. The product also claims technological advantages including an ability to change flexibly (since much of the configuration can be modified in operation by users and does not require domain experts), quick implementations and rapid implementations of new releases.
Protean was one of the first ERP applications developed exclusively using object oriented technology, albeit it has taken some time for the company to learn empirically how to improve performance and show true benefits to enterprises. Configuration of Protean is simple and intuitive through a combination of graphical tools for production models and screen forms that can be role-based customized for variety of users, without using training-intensive development tools. The product is also easily extensible because new objects and new data types can be added, again by power users only and without development tools. For example, terms that are more familiar within the particular manufacturing environment can easily supplant the corresponding default Protean's terms.
Ease of Upgrade
As a result, one Protean customer, with a different ERP installed in parts of the business, stated that it took less time to upgrade to a new Protean release than it took to estimate how long it takes to upgrade their other system to a new release. Because of Protean's ease of use, costing and shop floor functionality, it is one of the few ERP applications that can be deployed for process-oriented shop floor control. Although Protean uses the same patented production model concept as PRISM, it can be implemented using provided generic model templates that can significantly speed implementation and improve maintenance requirements, since the production model building is done graphically and can be readily assembled and changed.
exposed objects also give it a remarkable number and granularity of application
programming interfaces (APIs). While traditional procedural products must have
APIs written to allow interoperability, object-based products like Protean should
have the APIs natively built into the product. Therefore, the Protean's object
oriented product architecture has long boded well for its integration into a
heterogeneous and evolving application environment, which has unfortunately
not been highly appreciated until recently. Protean also leverages its object
architecture in workflow management, since FileNet's Visual Workflo,
can be linked to Protean's business objects to generate user-specific Protean
workflows graphically.
Therefore, IPS' foray into recently all-the-rage Web Services has much credibility, since the company has likely dealt with the pieces of the concept before the latest industry buzzword has even been conceptualized. Namely, using objects (Web Services), Protean objects are driven by business processes, which, by the nature of encapsulation (i.e., making functionality known only by the interface it exposes), bode well for the ongoing product's instance agility.
Services/service oriented architecture (SOA), which have lately been on almost
every vendor's lips, do have a potential of becoming the latest evolution of
application integration technology and/or a revolutionary new web-based application
design model by enabling developers to create or enhance applications by connecting
granular components that are recognized and accessed via platform-independent
Web protocols. While Web services leverage the aged (and not well utilized)
concept of objects' encapsulation and reusability, they may finally offer that
extra mile by adherence to standards that are increasingly taking hold (see
SOAP Opera Progresses - Helping XML to Rule the World). Further, Web Services
components tend to be simpler in their nature, partly owing to the Internet
standards, and they also tend to be higher-level abstractions, which implies
more likely platform independence and "mixing and matching" opportunity by developers.
Thus, the above changes in the market mindset should finally play to IPS' favor,
and should mitigate Protean's functional incompleteness, which has plagued it
in the past.
concludes Part One of a two-part note.
Two will discuss the Invensys's Liabilities, Strategy and make User Recommendations.


text:
SQL? NoSQL? MySQL!
Montag, 28. Oktober 2013 - 14:15 bis 15:15
- Forum 6
Web applications run under strong requirements – they have to be fast in delivering their results while working on a lot of data and serving many concurrent users. "Traditional" SQL-based access can cause too much overhead when other access patterns are needed. In this session we will take a look at MySQL and MySQL Cluster. with their different APIs, they serve users with SQL and different NoSQL APIs and allow switching between these so the most optimal can be used.


text:
Images are for reference only and may show accessories or configurations not packaged with this product. See Product Description below for details.
If you see it for less, Call Us, Live Chat, or Submit a Price Match.
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or is no longer available at Planet DJ.
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Akai Professional's MPC500 is the first truly portable all-in-one Music Production Center. Affording artists the ability to sample and create music on-the-go, the MPC500 offers many of the same features users have grown to love in the MPC line. From rock solid sequencing and programming to expandable memory and storage options, the MPC500 is only small in physical size. Compatible with other MPC products, the MPC500 extends users' studios to fit in with their mobile lifestyles.
• Sampling and Beat Creation
• MIDI sequencing
• Live Performance
• Travelling
Display: 2 x 16 character LCD w/back light
Memory card slot:Compact Flash (The size of the compact flash card that MPC500 can handle is from32MB to 2GB)
Dimensions: 266mm x 175mm x 44mm
Weight: 1.34 kg
Power requirement: 12v DC 600mA (negative tip)
Battery life: Approximately 4.5 hours of continuous use with LCD backlight ON.
Sound Generator
Sampling rate: 44.1kHz
Memory capacity: 16MB standard (11.5MB for sound memory), expandable to 128MB
Recording time: 136sec. (16MB, MONO) or 24m28sec. (128MB, MONO)
Memory expansion slot: 1 x for optional EXM128
Data format: 16-bit linear
Polyphony: up to 32 (dependent on processing)
Dynamic filtering: 2-pole lowpass filter per voice
Preset sound memory: 5MB
Number of programs: 24
Effects: 2 stereo effects and Master effect
Effect type: Chorus, Flanger, Bit grunger, 4 band EQ, Compressor, Phase shifter, Tremolo,
Flying pan, Reverb, Delay
Master effect: 4 band EQ, Compressor
Maximum events: 100,000 notes
Resolution: 96 parts per 1/4-note
Sequences: 99
Tracks per sequence: 48
MIDI output channels: 16
Song mode: 20 songs, 250 steps per song
Drum pad: 12 (velocity and pressure sensitive)
Drum pad banks: 4
Sync mode: MIDI clock
Record input (L and R): 1/4-inch stereo phone x 2, pseudo balanced -40dBu, input impedance 9k ohm
Max. Input level: +10dBu
Stereo output (L and R): 1/4-inch phone x 2 pseudo balanced +11dBu, output impedance 1k Ohms, Max.
Output level: +5 dBu
Phones output: 1/4-inch stereo phone x 1, 200mW / 100 ohms
MIDI inputs: 1 x 5-pin DIN
MIDI outputs: 1 x 5-pin DIN
USB: Slave connector x 1, USB MASS STORAGE CLASS support (Windows 2000/ME/XP or later version, or Mac OS 9.x/10.x or later version.)
Data Compatibility
MPC2000/2000XL: SEQ, WAV, SND, PGM (Most parameters of PGM file can be loaded.)
MPC4000: SEQ, WAV, PGM (DRUM program only. Only note assign and tune are loaded.)
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Church leaders from the Americas and the Caribbean are meeting in Nicaragua, to seek action on the violence of racism and the challenges it poses.
Substantial information on torture and human rights abuses was passed to the Brazilian Attorney General at a ceremony in São Paulo this week.
A conference on the often precarious situation of Christians across the Middle East is to be held in Volos, Greece, from 20 to 22 June 2011.
The General Secretary of the World Council of Churches, the Rev Dr Olav Tveit Fykse, arrived on 14 June in São Paulo, Brazil for a six-day visit.
Records of brutal torture and repression suffered under two decades of Brazilian military rule will be returned to the South American country today.
Escalating violence against civilians in Sudan's disputed South Kordofan State is leading to major humanitarian catastrophe, say Sudanese churches.
As Cuba moves toward a post-Fidel Castro society, its churches are finding ways to "give a Christian witness with integrity" in a state-controlled country.
The head of the WCC says commitment to peace and justice needs to be at the centre of the Christian churches' search for unity if they are to carry conviction.
The former General Secretary of the WCC has described the UN resolution authorising military intervention in Libya a "perilous" political decision.
Church responses to the challenge of climate change and environmental destruction has been the focus of a vibrant IEPC workshop.


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Our research focuses on immune responses to viral infections in the central nervous system (CNS), with an emphasis on persistent infections and immune-pathology manifested by demyelination. Neurotropic coronavirus-induced encephalomyelitis is used to investigate how resident CNS cells trigger and modulate immune function. Although innate and adaptive immune responses join forces to control virus, it persists in the CNS at low levels. Our goal is to dissect the contribution of distinct lymphocyte subsets to long-term virus control as well as demyelinating disease. These insights will assist in developing strategies not only to combat acute CNS infections, but also to maintain control of endogenous viruses during immunemodulatory treatment of autoimmune inflammation. Three projects are under way:
1. Characterization of innate immune responses in glia. We are investigating how type I interferon induced antiviral activities (OAS/RNaseL, PKR, IFIT1/2) affect viral control in distinct cell types.
2. Regulation of CNS-infiltrating T cells by inhibitory factors. Our studies revealed that efficient viral control by CD8 T cells is dampened by inhibitory factors but enhanced by CD4 T cells, which are also major effectors of pathology. Efforts are underway to understand the mechanisms underlying CD4 T cell help to CD8 T cells on one side, but enhanced neuronal damage on another.
3. Maintenance of humoral immunity within the CNS. Intrathecal antibody-secreting cells control virus re-emergence during the persistent phase of infection. Various transgenic and knockout mice are used to characterize factors regulating B cell entry, differentiation and maintenance within the CNS.
Dr. Bergmann's research explores how the immune system controls viral infections of the central nervous system (CNS), while minimizing tissue destruction. Her studies evaluate how specialized cells of the CNS respond to virus infection and how these responses contribute to recruitment of protective leukocytes circulating in the blood into the CNS. This work has revealed how various leukocyte populations and their distinct functions interact to control virus at distinct phases of disease. Ongoing research focuses on how specific immune functions can be manipulated to maximize viral control without leading to overt pathology involving neuronal damage.
Marques CP, Kapil P, Hinton DR, Hindinger C, Nutt SL, Ransohoff RM, Phares TW, Stohlman SA, Bergmann CC. 2011. CXCR3-Dependent Plasma Blast Migration to the Central Nervous System during Viral Encephalomyelitis. J Virol 85(13):6136-47.
Savarin C, Stohlman SA, Rietsch AM, Butchi N, Ransohoff RM, Bergmann CC. 2011 MMP9 deficiency does not decrease blood brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis. Glia 59(11):1770-81.
Phares TW, Stohlman SA, Hwang M, Min B, Hinton DR, Bergmann CC. 2012. CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis. J Virol86(5):2416-27.
Savarin C, Stohlman SA, Hinton DR, Ransohoff RM, Cua DJ, Bergmann CC. 2012. IFN-gamma protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils. J Neuroinflammation 29;9(1):104.
Kapil P, Butchi NB, Stohlman SA, Bergmann CC. 2012. Oligodendroglia are limited in type I interferon induction and responsiveness in vivo. Glia 60(10):1555-66.
Lerner Research Institute
Cleveland Clinic,
Mail Code NB21
9500 Euclid Avenue
Cleveland, Ohio 44195
Tel: (216) 444-3900


text: TNT will pay tribute to the late Larry Hagman's iconic character J.R. Ewing and lay him to rest when the Dallas reboot premieres its second season. Hagman -- who died in November at age 81 -- reprised his original role for the TV update and taped six episodes that will air throughout the season. (Mon., Jan. 28 on TNT)


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Rough Me Up by Maria Ritter.
Rough Me Up explores the lives of some rough and tumble
characters, who are busy trying to survive the streets and alleyways
of East Oakland, California.
7 for Hope by Jessica Caballero. This
is a farcical look at what could happen if a variety of characters
tried to insulate themselves from the havoc of the millennium.
State of Mind by Kristi
Join us in exploring the efficacies of dream therapy and discovering
love, loss, pain and their relationship to the ever-mysterious
psyche. A comic drama, this play searches far and deep for
answers to troubled minds.
Safe with Me by Alicia Nicole Moss .
A drama/mystery, Ms. Nicole Moss takes us on a very
special ride down and around the lives and hearts of her characters.
Just when you think you have a handle on what's going on,
it'll turn and twist again. Great audience work and delightful to
More information about dates:
May 10, 12 at 8pm: 7 for
Hope and Safe with Me
May 11,13 at 8 pm: State
of Mind and Rough Me Up
All shows will perform on May 14, starting at
7 pm (note the hour earlier, as we will be doing all the shows)


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The Planning and Development office is under the administrative oversight of the Division of Parks and Recreation.
The office is responsible for project management and design, regulatory permitting, and fixed asset management for all Department of Resources and Economic Development facilities. In addition, the office is responsible for recreational and public use planning, as well as policy development and implementation for the Division of Parks and Recreation.


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I do love a military inspired piece, this jacket from Isabel Marant is the perfect example. I love the subtle details, especially the pop of red under the collar. I remember buying this in Hong Kong on a whirlwind stopover, and was so excited to find it in the Isabel Marant store. Shell has exactly the same cut but in the overcoat version and in navy blue- great minds think alike!
Wearing Isabel Marant Daste jacket (similar here), Maje Envol shirt, Frame Denim jeans, Celine box bag (similar here), Isabel Marant Poppy heels.


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Document Number: 7511Choices, Changes and Challenges: Curriculum and Instruction in the NCLB Era - NCLB�s emphasis on reading and math has raised concerns that schools will respond by narrowing the curriculum. This report examines the amount of time spent on core academic subjects and how that allocation of time has changed since NCLB was enacted. The report finds that approximately 62% of districts increased the amount of time spent in elementary schools on reading and or math, while 44% of districts cut time on science, social studies, art and music and physical education. (Jennifer McMurrer, Center on Education Policy, July 2007)...
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Neopatriarchy: A Theory of Distorted Change in Arab Society
by Hisham Sharabi
Translations of this item:
On the level of practical politics, Sharabi deserves high praise for his candid diagnosis of Arab society; he calls it "for the most part, a culturally and politically desolate and oppressive place". This is the sort of forthright and courageous analysis the Middle East needs, especially from the inside. Too, his call for change in the Arabic-speaking countries is all to the good. Who would dispute his appeal for "limiting violence, humanizing social relations, liberalizing political life?" Or an emphasis on the need to attain human and political rights? Or a denunciation of the barbarities committed in the name of fundamentalist Islam?
The trouble is, it takes 150 pages for Sharabi to reach these fairly banal conclusions. Worse, he gets there via a convoluted, quasi-Marxist theory of "petty bourgeois hegemony" and the "neopatriarchal discourse." Along the way, he drops the names of every trendy theorist from Roland Barthes to Jörgen Habermas, with the usual bow to Marxist and Weberian icons. Sharabi hopes his book will stimulate Arabs to take action to improve their lot; but its obscure argument and superficial goals make the achievement of this goal highly dubious. Worse, he offers no practical ideas on how to get from here to there. Much better and more effective would have been to leave out the wordy theoretical sections and replace them with some constructive ideas how the worthy goals he sets out are to be achieved.
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What can I expect to do in this role?As the Planning Biologist Intern you will assist the Timmins District Planning Biologist and District Planner with biological and ecological information collection, management, analysis and reporting for the purpose of natural resource planning and management.How do I qualify?Mandatory• Proof of eligibility to in Canada.• Proof of full-time enrolment in a recognized post-secondary college or university or graduation within the last five years.• Candidates are only eligible to participate in a maximum of two placements.Knowledge and Skills• Knowledge of biology and ecology including conservation biology and the natural sciences.• Knowledge of current natural resource inventory, monitoring, and assessment techniques with regard to natural landscapes, wildlife habitat, geology, water quality and quantity, and other values.• Knowledge of resource management planning processes, including, but not limited to water management, forest management, land use and protected area planning as well as the legislative and planning tools that support these processes.• Organizational, analytical, problem solving skills and oral and written communication skills to communicate a variety of information.• Interpersonal skills and ability to work independently and in a team environment.• Working knowledge of standard personal computer software including word processing, spreadsheets, e-mail, internet browsers and geographic information systems and mapping.Note: The successful candidate will begin at the base-level pay rate and will move up in the pay scale in accordance with the OPSEU collective agreement.
Additional information:
Job advertisements for positions that have been designated bilingual will be provided in both English and French on the website. Positions that are not designated bilingual are not translated and are displayed in English only on both the English and French versions of the website.
Les annonces d'emploi pour les postes désignés bilingues sont publiées en anglais et en français sur le site Web. Les annonces pour les postes qui ne sont pas désignés bilingues ne sont pas traduites et elles figurent en anglais seulement, tant dans la version française que dans la version anglaise du site.
The Ontario Public Service is an inclusive employer.
Accommodation is available under the Ontario Human Rights Code.
Note: The only website where you can apply on-line for positions with the Ontario Public Service is http://www.gojobs.gov.on.ca
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Brad Williams, center, tries to break through the South Sevier defense on Jan. 3
Zac Hathaway, left, fights for possession with a South Sevier player on Jan. 3.
With just five games left on the schedule, the Carbon High boys basketball team has plenty of opportunities to turn things around.
Despite a 1-15 record overall and an 0-3 mark in Region 12 play, the Dinos will play three of their final five games at home.
The Dinos took on Payson on Wednesday, Jan. 29 and will host North Sanpete in another Region 12 game on Friday, Jan. 31 at 7 p.m. at the CHS Gymnasium.
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On 14 September this year, one and a half years after the Fukushima Daiichi nuclear accident, the Japanese Government released an unprecedented document.
The "Innovative Energy and Environment Strategy", the culmination of a year-long policy review process, set the previously unthinkable target of zero nuclear energy by the end of the 2030s. In resolving to phase out nuclear energy, the Japanese Government did what it had never done before in the energy policy field: it allowed itself to be influenced by the will of the people.
The backlash was immediate. Business groups banded together to condemn the strategy, governors of prefectures hosting nuclear facilities expressed concern about the future of these facilities and, perhaps equally significant, the governments of France, the UK and the United States communicated their displeasure. In the face of this onslaught the government went weak at the knees and failed to give the strategy formal cabinet endorsement.
When the direction of the energy policy review process was first announced at the end of July 2011 a so-called "national debate" was firmly on the agenda, but before it could begin, the parameters had to be established. A series of committees spent the better part of a year drafting policy options for the public to consider. Then in July and August this year the public was invited to consider three options for the proportion of nuclear energy in Japan's electricity generation mix in 2030: zero, 15 per cent, or 20 to 25 per cent.
The national debate, which involved public comments, public hearings and a deliberative poll, took place against a backdrop of massive protests against Japan's nuclear power plants. Every Friday evening, tens of thousands to hundreds of thousands of people turned out in Tokyo's political district to protest. Unlike past protest movements, this one did not have any clear organisational backing, so it could not be dismissed as "the usual suspects".
Despite the protests the outcome must have surprised the government. It appears that 15 per cent nuclear was their preferred option, but the overwhelming majority of participants in the public hearings and nearly all the 90,000 public comments favoured a total phase out. In many cases they didn't want to wait till 2030; they wanted Japan's nuclear power plants to be permanently closed down now.
The outcome of the deliberative poll was not so overwhelming, but in some ways it was even stronger evidence of public support for a nuclear phase out. The support for the zero option among the almost 300 randomly selected participants in the two day event became more and more pronounced as the deliberative process proceeded.
Presented with such a conclusive rejection of nuclear energy in a public participation process on which it had staked its credibility, the government was forced to bend. It had to include the "zero" word somehow. But the strategy that it came up with was patently contradictory, purporting to support the continuation of the existing nuclear fuel cycle policy and stretching out the phase out deadline to the end of the 2030s, while providing no credible pathway to zero.
France and the UK's public reaction to the Innovative Energy and Environment Strategy related to Japan's responsibility to accept the return of radioactive waste from spent nuclear fuel reprocessed in their countries. However the response of the United States was more complex.
The United States is concerned about the proliferation implications of Japan's massive plutonium stockpile, which currently stands at 44 tons, enough to make over 5000 Nagasaki-style bombs. If Japan goes ahead with its nuclear fuel cycle program, in particular reprocessing spent nuclear fuel, this plutonium stockpile will grow even larger. But if Japan intends to phase out nuclear power, it will have no reactors in which to use this plutonium.
The US Government could have responded in either of two ways: by stating that it would retract permission to reprocess spent nuclear fuel sourced in the United States, or by pushing Japan to retract its nuclear phase out strategy. It has certainly expressed its concern about the implications of the contradictory strategy for Japan's plutonium stockpile, but it seems to be emphasising the latter approach, namely calling for Japan to remain committed to nuclear power.
At least one of its motivations is not hard to fathom. In recent years Japan has become more than just a customer for the US nuclear industry. The current state of US nuclear industry is such that it would be hard pressed to construct nuclear power plants without Japanese cooperation. In fact, Toshiba now owns Westinghouse, while GE's nuclear operations are run through subsidiaries jointly owned with Hitachi.
The Innovative Energy and Environment Strategy was considered by Cabinet on 19 September, five days after it was released, but to everyone's surprise cabinet did not formally endorse the document. It simply noted it, saying, "The Government of Japan will implement future policies on energy and the environment, taking into account of the Innovative Strategy on Energy and the Environment."
On 22 September the Tokyo Shimbun newspaper reported that the US Government had demanded that no cabinet decision endorsing the strategy be made. Other newspapers reported that the US Government was pressuring Japan to abandon its nuclear phase out aspirations.
More recently a series of statements by former senior US officials and advisors suggests a concerted campaign could be underway to intimidate the Japanese Government. These people claim that Japan without nuclear power would be bad for nuclear non-proliferation. The basis for this claim is not fears about Japan's plutonium stockpile. Rather it is that allegedly Japan without an active nuclear power program would be less able to support the United States' non-proliferation efforts.
John Hamre, a former US deputy secretary of defense, said, "The champions of proliferation prevention were the United States, Europe and Japan. ... [I]f Japan stops being nuclear, if America stops being nuclear, if Europe stops being (a collection of) nuclear power countries, who is going to run the global system of security and safety?" This says nothing for the counter-argument that Japan as a leader in renewable energy and energy efficiency would be a powerful advocate for a nuclear-free future.
The question arises, will the public will expressed in the national debate be over-ridden by pressure from overseas? Will the first tentative steps towards participatory democracy in Japan's energy policy be thus undermined?
The United States has no right to tell the Japanese whether or not they should phase out nuclear power. On the other hand, countries like Australia which have nuclear cooperation agreements with Japan have a legitimate right to demand that Japan not add to its plutonium stockpile. They have every right to demand that Japan not separate any more plutonium at its reprocessing plant in Rokkasho.
A national election is scheduled for 16 December. Due to the general confusion in Japanese politics the election may not deliver the type of clear verdict on nuclear energy that one would otherwise expect. But whatever the outcome, Japan is undergoing a historic shift in its energy policy. The Japanese people need international support in this process, but they don't need to be bullied.
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Tim Macknay
Posted Friday, December 7, 2012 - 19:04
My biggest concern with the nuclear phaseout policy is that it will lead to an increase in Japan's greenhouse gas emissions. Ditto the German phaseout policy. I'm no particular fan of nuclear energy, but next to fossil fuel burning, it's decidedly the lesser evil.
A large scale renewables rollout (which I support) will take at least a couple of decades to complete and in the meantime, any early phaseout of nuclear could derail emissions reductions efforts. I'd prefer a phaseout of fossil fuel generators first, then nuclear, rather than the other way around.
I can't blame the Japanese for wanting to get rid of it, though.
Posted Saturday, December 8, 2012 - 19:54
The imperial mentality would be hilarious if it weren't so serious. I remember the United Statesians tried to tell us Kiwis our Labour Politicans weren't allowed to show Michael Moore films at fundraisers. I hope the Japanese are able to chart their independent democratic course - for me it'd be worth it just to see the histrionics from Washington. Simply intolerable to the mafia boss that the weak should take decisions for themselves against his interest.
Posted Sunday, December 9, 2012 - 19:18
nulliusinverba, bloody brilliant comment.
But that about sums it up.
Posted Tuesday, December 11, 2012 - 14:27
It can be hard for Australians to comprehend the deep seated fear of nuclear technology in Japanese society. It's not just that Fukushima happened, it's that the Fukushima accident happened to the only nation on Earth that has had major cities blown to smithereens by atom bombs.
Imagine that the same three events happened to Australia and that tragic history would indelibly colour our cultural attitude to all things nuclear. The separation between peaceful and non-peaceful use of the atom is now blurred forever in Japanese eyes.
Posted Tuesday, December 11, 2012 - 16:03
Can we get some details on what the Japanese government is proposing as an alternative to its nuclear power generation? I can't imagine they'd be replacing it with Coal plants.
Frank from Frankston
Posted Tuesday, December 11, 2012 - 18:42
@chrisharries, the unfortunate truth is, no country which possessed a viable nuclear deterrent has ever been atom bombed by a rival.
The only country ever to have suffered a nuclear attack, suffered it, because it did not possess the ability to retaliate.
MAD was not in play. As it was during the long, long, cold war.
Added to this mix, is the realisation that the next nuclear strike may be carried out by groups not representing any nation, against a nation.
Surely that is the message from the Twin Towers attack on NYC.
For Japan, the next most likely deliverer of the next nuke weapon is the PRC. That ought to be obvious.
What would prevent a communist dictator in the PRC from dropping a bomb on Japan? Or Australia?
Would a viable nuclear deterrent stop them?
Posted Wednesday, December 12, 2012 - 07:26
Frank, extrapolating your thought that to arm one self with nukes renders you safe from enemies a logical conclusion would be that if all of the worlds 200 plus nations armed themselves with nukes then nobody would get hurt. That's the theory that kicked off the arms race.
Some do agree with that thought (I don't) but the article was really about nuclear energy, not weapons proliferation. I was simply alluding to the (understandable) state of mind of the Japanese people, accepting the history of events they have experienced.
Posted Wednesday, December 12, 2012 - 12:27
A few points - the nuclear industry is in decline because the economics don't add up - it always operated as a symbiot with a nuclear arsenal - countries with few energy options the exception.
Fukushima is a 1970's style facility like many in the US that should have already been shutdown but their lifespan is being repeatedly extended because decommissioning costs are astronomical.
Leaked documents from the Japanese cabinet revealed that if the plume from the Fukushima diaster had not predominantly blown out to sea but had gone to the south west, Tokyo would need to be evacuated - when dicussing this the cabinet had to consider the scenairo of Japan becoming a failed state. Prolonging the Nuclear cycle in Japan, (like its plutonium facility which still does not work after decades of funding) is not really an option and what to do with the waste? Japan like the rest of the world is facing a slow permanent decline.