text:
An Interview with Department of Buildings
Commissioner Chandler and Deputy Commissioner Hogan
On Tuesday, January 13th
2015, the Greater New York Construction User Council held a program
titled, "A Conversation with the Commissioner: Meet the Department
of Buildings Leadership." The program featured Rick Chandler,
Commissioner, Department of Buildings and Timothy Hogan, Deputy
Commissioner of Enforcement, Department of Buildings who were
interviewed by Greg David, Director, CUNY Graduate School of
Journalism and former editor of Crain's New York Business. Jack
Osborn, who serves as the General Counsel to the Greater New York
Construction User Council, helped organize the program. The program
examined the Department of Buildings' current agenda and reviewed
the DOB's priorities. .
Read More
Major Hotel Executives Reflect on the
Continued Growth of Tourism and Hotel Inventory in New York City
On The Greater New York
Construction User Council ("GNYCUC") and the Hotel Engineers
Association of New York Inc. ("HEANY") were conference partners for
the Second Annual New York City Hotel Forum, at the McGraw Hill
Building in Manhattan on Friday, November 7, 2014. The conference,
which included two panels of industry executives, examined the
future of the hotel industry in New York City and current
development trends.
Read More
Jack Osborn Receives New York Society of
Architects Distinguished Service Award
On Wednesday, November 19,
2014, Jack Osborn was presented with the Distinguished Service Award
at the New York Society of Architects Dinner Dance. The award is
presented each year to a professional who has made an exceptional
contribution to the architecture and construction community in New
York City.
Read More
GNYCUC Presents "Modern Office Design
Panel: What Tenants Want"
On Tuesday, October 7th the
Greater New York Construction User Council ("GNYCUC") held a
program, "Modern Office Design Panel: 'What Tenants Want'" at
Gensler. John E. Osborn, Esq. serves as the General Counsel to the
GNYCUC. The panel featured moderator, Joe Brancato, Regional
Managing Principal, Gensler, Joel Brenner, Vice President of Global
Project Management, Time Warner, David Biondolillo, Senior Vice
President, TD Bank and James V. Cava, Director of Global Planning,
Citibank. The panelists discussed their current projects and shared
their thoughts on the future of the office environment.
Read More
Environmental Due Diligence and
Project Planning in Stormy Times
Jack Osborn and Mark
Pennington taught a continuing legal education program at the Firm's
offices on March 4, 2014 entitled "Environmental Due Diligence and
Project Planning in Stormy Times." Jack Osborn is Head of the Firm's
Construction Litigation Practice. Mark Pennington, Of Counsel to the
Firm, is the head of its Environmental Practice.
The program examined ASTM's
revised environmental due diligence standard (E1527-13) within the
larger context of risk management. It offered tips on tailoring
transactional due diligence and selecting and managing environmental
Read More
The City of New York Abandons the
No-Damages-for-Delay Clauses in Construction Contracts -- 30 Years
After the Kalisch Jarcho Decision
As of December 24, 2013, the
City of New York (the "City") and its various agencies are using a
new standard construction contract. Of the several revisions, the
most impactful, at least from a contractor's perspective, is the
elimination of the no-damages-for-delay (NDFD) clause. This clause,
which had been faithfully used by City agencies and staunchly
defended by New York courts for decades, has been an effective tool
for owners (public and private) and contractors to shift the risk of
additional costs associated with project delays and other time
related impacts onto the respective contractors and subcontractors.
Read More
©2015 John E. Osborn P.C. l
841 Broadway, Suite 500
New York, NY 10003
l Phone: 1.212.576.2670
Legal Notices
l Attorney Advertising


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A total afterthought of a behind the scenes style video for a shoot Josh Valcarcel and I did. Using a trash bag stretched tightly over a speaker, we put paint on the trash bag, played some music, and took some pictures. For more photos visit ryanbuller.com or joshvalcarcel.com.
Music Credit:
"I Believe" by
Simian Mobile Disco
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text:
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Rate Dr. Craig P. Greenberg
Dr. Craig P. Greenberg's Ratings
One of the best doctors I have ever seen. Thorough, caring, excellent all around. He runs late sometimes because he gives patients as much times as they need; well worth the wait. Hands on ... personally calls me with test results, personally administers treatments others might out source to a hospital tech.
Was this rating useful? 0 [[ userState['ratings'][2905148].votes_count ]]
Dr. Greenberg is incredibly intelligent, and is willing to work to find the root of the problem. I'm so happy to have found him! I had a list of questions ready to ask him, but by explaining everything in depth (and he talks fast!) I only had one question to ask at the end, which was unrelated to why I was there. He does run behind schedule, but I can appreciate that because he's taking the necessary amount of time to care for each patient. Excellent doctor, totally worth waiting to see.
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Dr. Greenberg was amazing. Finally a physician willing to take the time to explain my disease. To many physicians hand you a prescription and say see you in four months. After having a lot of problems lately, I thought I would give a need provider a try. It only took him a matter of minutes to find the underlying cause of my problems. I'm very fortunate to have him!
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I have never worked with a more arrogant doctor.
He won't last long .
Was this rating useful? 0 [[ userState['ratings'][2596702].votes_count ]]
LOVE, LOVE, LOVE Dr. Greenberg. He tends to run late, but that's because he gives his patients all the time they deserve. Now my spouse is also one of his patients, and even my parents drive from out-of-state to see him.
Was this rating useful? 0 [[ userState['ratings'][2102665].votes_count ]]
He is the best doctor in town. He is very smart and listen to his patient. I am proud to meet him as my doctor. He will have large number of patients due to good and best references. He kept me alive.
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Dr. Greenberg was very helpful with my thyroid issues. He spent quite a bit of time with me..he was not rushing me. He listened to absolutely everything I had to say! I would highly reccommend him to anybody!
Was this rating useful? 0 [[ userState['ratings'][2102663].votes_count ]]
Listens & takes time to evaluate your problem.I also use armour thyroid and he is willing to prescribe it to me. I am a firm believer in natural thyroid medication
Was this rating useful? 1 [[ userState['ratings'][2102662].votes_count ]]
Talks fast but very intelligent. Pleasant Personality.
Was this rating useful? 0 [[ userState['ratings'][2102661].votes_count ]]
What a joy Dr. Greenberg is! He listens, he's accomodating and he takes as much time as you need to help you with your problem. He also is one of the few endos who will cheerfully prescribe Armour thyroid (even though he's not keen on it). The only downside is that he always runs very late with his appointments (because he listens). A tip: call before you go and see how late he's running, then show up then.
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California shooting guard Allen Crabbe, a third-team Sporting News All-American and Pac-12 player of the year, will surrender his final season of NCAA eligibility to enter the NBA draft.
Crabbe averaged 18.4 points as the Bears made a late run that grabbed an NCAA Tournament bid, and he scored 19 points as the No. 12 seed Bears upset No. 5 seed UNLV in the round of 64. He scored just eight in his final college game, a loss to Syracuse.
"It has been a dream of mine to play at the next level for a long time and I feel deep down in my heart this is the right decision," Crabbe said in a release from the school. "I have thoroughly enjoyed my time at Cal and learned a lot from my coaches and teammates. I will miss a lot of people at this University both in basketball and in school. I will always be a Golden Bear at heart."
A 6-6 junior from Los Angeles, Crabbe is not a lock to be selected in the draft's first round. He is projected as the first pick of round two by DraftExpress.com.


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For an easygoing moving-day look that still boasts superb style, be sure to don this grey and white top! This colorblocked, short-sleeved blouse flows gracefully with your every step as you unload boxes, greet new neighbors, and gleefully decorate your new abode. Pair the pocketed top with a large-faced gold watch, cropped denim, and patent peach flats for a look that's sure to receive a warm welcome from all who catch sight of it!
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posted by Rebecca Keenan | 0 Comments
I started the day off with a trip to Anfield, home to Liverpool Football Club. This impressive stadium is just a short trip from the city centre.
I took the stadium tour, which lasts around an hour. Along the way, I got to see the dressing room, check out the padded seats reserved for the high ups, and even sit in the world-famous Kop area of the stand! The guides were brilliant, full of really great bits of information about former managers, players and more.
After this I headed back into the city centre, did some filming around the World Museum and then went for lunch in the Everyman Bistro which is underneath the Everyman Theatre. It was absolutely delicious and great value too!
Then I headed towards Liverpool's Anglican Cathedral, where I took 2 lifts and climbed 108 stairs to get to the top of the seriously striking tower. Here I saw amazing views of the whole of Liverpool spread out below. I also learned a quirky little fact during my visit! The guy who designed this cathedral? Also the same guy who designed the red telephone boxes you see throughout the UK!
Once I'd spent some time at the Cathedral, it was back to Hatters Hostel to arrange my evening's entertainment!
Cassandra C said
" Ha Long Bay, Vietnam! I went skinny dipping at night there, and there were l...
Alex Tyner said
Ram said
" Beautiful places i loved it find out some interesting places in the Himalayas
Josh Freeman said
Saulo said
" Cool places! Here in Brazil we have some nice places for that as well. Check Bo...


text:
Jupiter Design
I like to do illustrations in a way that most people does not.
Yes, I do use Photoshop like many others, but my artpieces are done with just Brush and Eraser in Photoshop and a Mouse. Yes. A mouse. I prefer that over a tablet anytime!
I guess I just really love the jagged outlines and effects a wobbly and unsteady mouse can give. It seems to give a high-fidelity old school comic book effect which I hope you guys love.
Hopefully over time, I can produce more and more works for you!


text:
Indian River tax collector opposes using County Administration Complex parking lot for new GoLine hub
INDIAN RIVER COUNTY — Tax Collector Carole Jean Jordan, whose driver license applicants are tested on specific routes, Tuesday joined the ranks of residents opposed to GoLine bus drivers switching routes in the County Administration Complex parking lot.
"(Applicants) need to make a specific number of right and left turns in their driver's license tests," Jordan said. "So you can't say, 'Just use a different route.' This was approved by the state."
Commissioners on Jan. 22 agreed to move the route-transfer hub in response to a notice from the Vero Beach Code Enforcement Division.
The zoning for the current hub, an old county parking lot on 26th Street, doesn't allow bus stations, city planners have said.
The county contracts with the nonprofit Senior Resource Association to operate the GoLine buses, a system of 15 fixed routes providing about 600,000 trips annually throughout the county and into Barefoot Bay in Brevard County.
Linda Hillman, past president of the Original Town Neighborhood Association, had objected to the traffic impact from the current site and complained of strangers traveling through residential streets to get to and from the hub.
"Me, I'm dancing the 'happy dance,'" she said Tuesday.
The bus hub won't be in her neighborhood for much longer. But still, she said, the people who loiter around the current portable toilets might well loiter inside the county buildings for the restrooms.
Resident Jessica Durkee complained of the bus hub attracting homeless people into the neighborhood. And although some of them might be honest citizens, she said, "It just takes one bad apple to spoil the barrel and 95 percent of these apples are bad."
Commissioner Tim Zorc said county officials are also looking for better locations.
"I've gotten a lot of calls about this," he said. "We need a central location, but wherever this ends up, someone is not going to like it."
City and county officials recently looked at moving the hub to 1.5 acres the city owns, south of 16th Street and west of the Florida East Coast railroad. However, they disagreed on who should maintain the site's landscaping, prompting the county to drop that idea Dec. 18.
Local government critic Charlie Wilson, who recently formed a political action committee to replace County Administrator Joe Baird, accused Baird of using the landscaping issue as a "ruse." By Baird moving the bus hub to the county campus, Wilson said, GoLine could spend a $1.1 million federal grant on other transit needs.
Baird couldn't be reached later for comment.
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text:
It's been a decent comeback to racing for Álvaro after the brief summer break, taking home a good fifth place from Indianapolis. After a solid start from eight position, having moved up one place with Nicky Hayden unfit to race, he settled in the second group around sixth place while at the front home rider Ben Spies and Dani Pedrosa, who so far dominated the proceedings this weekend, were running away from the rest of the field. Unfortunately for Spies it was yet another race that ended badly as with just a handful of laps gone his engine blew up on the straight and he left behind him a lot of smoke and a bit of oil on the track which fortunately was off the racing line, so the race could continue normally.
But that incident was enough to put several seconds between the group Álvaro was in and Jorge Lorenzo riding in second place, already far behind Pedrosa, with no chance for the group to make up the gap. The group initially consisted of Andrea Dovizioso, a very brave Casey Stoner who also battled his severe ankle injury, Alvaro, Stefan Bradl and Cal Crutchlow. With Crutchlow soon crashing out there were only four riders left to fight for the final podium position and once Álvaro passed Bradl for fifth place he opened up a gap of several seconds which the German could not close again until the finish line.
Álvaro kept up his good pace to stick with Dovizioso and Stoner, posting his best laptimes of the weekend and getting into the 1'39s for the first time. Only with half of the race gone he slowly started to lose out a bit more, the gap getting to over a second, but he managed to keep it steady and continue his good pace until the end where he took a solid fifth place with a gap of 2.7 seconds to Stoner and just over five seconds to Dovizioso in third.
With no crashes this weekend and solid progress in all sessions, having the podium positions in sight until the finish line, it was a good confidence boost for Álvaro who finally seems to have found his pre-Mugello form again and it should give him and the team a lot more motivation for the upcoming race next weekend in Brno.
Pos. Rider Team Time/Gap
1 Dani PEDROSA Repsol Honda Team 46'39.631
2 Jorge LORENZO Yamaha Factory Racing +10.823
3 Andrea DOVIZIOSO Monster Yamaha Tech 3 +17.310
4 Casey STONER Repsol Honda Team +19.803
5 Alvaro BAUTISTA San Carlo Honda Gresini +22.556
6 Stefan BRADL LCR Honda MotoGP +30.072
7 Valentino ROSSI Ducati Team +57.614
8 Karel ABRAHAM Cardion AB Motoracing +1'08.442
9 Yonny HERNANDEZ Avintia Blusens +1'11.106
10 Aleix ESPARGARO Power Electronics Aspar +1'14.079
11 Toni ELIAS Pramac Racing Team +1'26.305
12 Ivan SILVA Avintia Blusens +1'40.274
13 Colin EDWARDS NGM Mobile Forward Racing 1 Lap
14 James ELLISON Paul Bird Motorsport 1 Lap
15 Steve RAPP Attack Performance 1 Lap
16 Aaron YATES GPTech 1 Lap
Not Classified
Cal CRUTCHLOW Monster Yamaha Tech 3 19 Laps
Randy DE PUNIET Power Electronics Aspar 20 Laps
Ben SPIES Yamaha Factory Racing 22 Laps
Michele PIRRO San Carlo Honda Gresini 27 Laps
Mattia PASINI Speed Master 0 Lap
Danilo PETRUCCI Came IodaRacing Project 0 Lap


text:
High School Football
Trinity's Lions hungry to hit field after long wait
by Chris Goltermann
Fasting is never a healthy option when it comes to eating habits. But when it comes to football, Trinity Christian head coach Chris Hanson may be onto something should his Lions roar through tonight's season opener against a tough John Milledge lineup.
Trinity hasn't sniffed much of a game setting since losing in the first round of last year's GISA Class AAA state playoffs. No spring scrimmage. No 7-on-7 passing competitions and no preseason scrimmage to quench the Lions' thirst for football heading into play against a Trojan program that reached last year's Class AA semifinals.
Both teams are going through its share of transitions after losing standout senior classes. They include 18 from John Milledge's 12-1 season, the best in program history while improving to 19-5 overall under former Georgia Bulldog fullback J.T. Wahl.
Trinity marches on after losing its starting quarterback, top-two rushers and its two leading tacklers from a 6-5 season, also best among the Lions' first-two ventures in GISA play following an 8-man championship.
It may all add up to a dogfight similar to last year's 14-6 game where John Milledge used an extended third-quarter drive as the difference maker while mostly held in check by an improved Trinity defense.
The Trojans opened the season last week with a 13-12 loss to Brentwood on a rain-soaked Friday in Sandersville.
"They're physical, they execute well. It's going to be a dogfight kind of game," Hanson said. "It's going to come down to who's the most physical and who does the least amount of turnovers. Last year, they scored, we scored, [our] defense held, [their] defense, held and they took the time of possession in third quarter and made that the difference in the game. They're capable of moving the ball, doing good things. We've just got to minimize mistakes and execute in all three phases."
Hanson and his staff, which now has Jeff and son J.P. as opposing coordinators on offense and defense, have kept most of its gameplan for 2013 under wraps this preseason.
Seniors Daniel Shoates and Joe Hogan have both touted as potential starters at quarterback, with Shoates seeing snaps the last two seasons. The Trinity backfield is equally brand new with transfer J.D. Farlow, who rushed for over 2,400-yards and 34 touchdowns with Heritage Christian in the Lions' former 8-man league. Converted tight-end Conner
Owen moves to fullback and linebacker with hopes of filling some of the gaps left by standouts Drew Gibson and Edwin Rivera, both now playing for college programs.
John Milledge went through equally heavy losses to graduation that included its starting quarterback, top rusher and top receiver. Returning senior Tommy Pittman tried to pick up some of the load last week while rushing for 111 yards on 21 carries while junior Chase Register and senior Hunter Harding led the Trojans with 12 and nine tackles respectively.
Hanson may be hoping that the extended wait and the team's energy level provide a perfect combination to starting this fall off better than in 2012.
"You would have like to have a game or scrimmage. I don't think that would have done much," he said. "But with this group of guys, they're hungry."


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Grand Haven freshman Lauren Strong was named the 2013 recipient of the Lela Johnson Award at the Buccaneers' basketball banquet on Monday.
The award is presented annually to a Grand Haven girls freshman basketball player who displays the same traits that Lela Johnson possessed — outstanding sportsmanship, academic achievement and a love for the game.
Strong was the leading scorer (108 points) and rebounder (81 boards) for the Buccnaeers' freshman team this winter.
The award is presented each year in memory of Lela Johnson, who died of a heart attack as a freshman at Grand Haven in April of 2003. Buccaneer varsity coach Katie Kowalczyk-Fulmer described Johnson as a talented, courageous athlete, who found a way to blend her faith with her love of basketball together. She was involved in First Priority, a student-led, non-denominational middle and high school campus outreach ministry.
Lela Johnson was the daughter of Judy Ketner and Jeff and Kathy Johnson.


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Online Café is not your typical Internet Café'. When the founders of this unique airport concept thought of mixing business and pleasure, the idea of the Online Café was born. Visit us and enjoy our casual fine dining and ask us about our added traveling conveniences:
Full-service and homemadeFor ten years, Online Café Bar and Grill has been offering travelers and business patrons the best in made-from-scratch food choices. You can settle in and enjoy soups,Black Angus Beef burgers (charbroiled to order), panini sandwiches, wraps, salads, and breakfast items and specialties. Everything on our full-service menu is made on site.Carry-outIf you're short on time but want a satisfying meal or snack, call (734) 942-9791 or fax (734) 942-9781 and order from the carry-out menu. Office and cyber caféOnline Café Bar and Grill is an "office-away-from-the-office" and a cyber café where you'll find:• Printing, copying, and faxing (international and domestic) capabilities• 10 Laptops for use, 36 modem connections and wireless T-1 access. With unlimited all-day use during business hours for only $7.00, or quick checking of emails for $3.00 for 15 minutes. • Servers and managers who are happy to assist youBarYou're welcome to visit the fully stocked bar or unwind and watch television on any of our 9 flat screen televisions.
The Westin connectionStaying at the Westin? Large business groups are easily accommodated, so please don't hesitate to come by to enjoy breakfast, lunch, or dinner, or to conduct a meeting while dining.We also cater to other businesses in the airport and offer a 10% discount to all airline employees.Visa, MasterCard, American Express, Discover; iDine.com member rewardsRecognized by Airport Revenue News: Concessions International North American, Best Food and Beverage program, Best Retail/Specialty program, 2007.
Website powered by Network Solutions®


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With sustainability growing in importance to civil engineering, ASCE has made it one of three strategic priorities for the Society, helping professionals to incorporate sustainability principles into their daily practice. As the stewards of society's infrastructure, civil engineers must take the lead in applying sustainability to planning, design, and construction.
ASCE defines sustainability as: A set of environmental, economic and social conditions in which all of society has the capacity and opportunity to maintain and improve its quality of life indefinitely without degrading the quantity, quality or availability of natural, economic, and social resources.
Leadership Resources
ASCE provides the resources and programs civil engineers need to lead as sustainable and innovative problem solvers. Since 1996, the Society has formally recognized civil engineers' obligation to practice sustainability by making it part of its Code of Ethics. We demonstrate our commitment to sustainable practice through our public policy statements, technical codes and standards, and in our global leadership and contributions to organizations such as the World Federation of Engineering Organizations.
Professional Tools
Whether you want to broaden your practice or develop the depth of knowledge that establishes you as a sustainable infrastructure professional, ASCE offers the courses, conferences and certifications you need to increase your sustainability knowledge.
Innovation in Sustainable Civil Engineering Award
Since 2011, ASCE has honored a civil engineering project annually for its inspirational applications of sustainability with the Innovation in Sustainable Civil Engineering award. Nominate one for the next award.
EnvisionTM Rating System
Envision measures the sustainability of an infrastructure project from design though construction and maintenance. Design teams and project owners use it to set and achieve sustainability goals, adopt and implement effectively sustainable choices, and help set standards for others to follow. The ratings system is administered by the Institute for Sustainable Infrastructure, which was founded in 2010 by ASCE in partnership with the American Council of Engineering Companies and the American Public Works Association.
Sustainable Engineering
Found in the ASCE Roundup, "Sustainable Engineering" shares recent developments and discussion topics, highlighting projects and innovations that embrace the sustainability "triple bottom line" – environmental, economic, and social conditions – thereby enhancing quality of life for all of society.


text:
Weber Hodel Feder
brogue detail hi-top
Out of stock
Unfortunately this item is out of stock
Yellow calf leather brogue detail hi-top from Weber Hodel Feder featuring a round toe, a rubber sole with a slight wedge heel, a pull-on tab at the rear and four velcro fastening straps at the front.
Item ID: 10306144
- Lining Composition
- Calf Leather 100%
- Outer Composition
- Calf Leather 100%
- Sole Composition
- Rubber 100%
- Brand Style ID
Your order will be shipped directly from the boutique to you. Farfetch ships worldwide using DHL and UPS, and you will be able to track your order at any time. The cost of shipping your order will be calculated at the checkout.
Import duties information
Delivery duties are included in the item price when shipping to all EU countries plus USA, China, Canada, Switzerland, Singapore, Australia, Japan, South Korea, Kuwait, Qatar, U.A.E, Saudi Arabia and Taiwan.This means all import duties are included in your order, so the price you see is the price you pay. You will not receive an additional duty bill from the courier to receive your shipment. If you are ordering from within your own customs zone or country, import duties will not be applicable anyway, however you may have to pay VAT or local Sales Taxes where applicable (for the UK and USA these are included at the checkout).
Delivery duties are not included in the item price when shipping to all other countries. This means you may be liable to pay import duties on receipt of your order.
Free returns pick-up
You have 14 days from receiving your order to return the item to the boutique using our free returns pick-up service. We strongly recommend that you book your free returns pick-up within 7 days of receiving your order to ensure that it arrives back to the boutique in time. Please note for standard orders we can only collect returns from the same country to which your order was delivered. For click and collect orders we can collect your return from the country your order was delivered to and also the country of the original boutique you ordered from. We are unable to accept returns of earrings for hygiene reasons. We are also unable to accept returns of fine Jewellery. Click here to read our full returns policy.
Weber Hodel Feder was founded by Swiss-German trio Matthias Weber, Niklaus Hodel and Florian Feder and based in Antwerp, Belgium. After meeting at the Royal Academy of Fine Arts, the three decided to combine not only their names but also their creative experience into a shoe label. The resulting footwear offers an elegant yet playful twist on the traditional.


text:
New to ePHOTOzine? Join ePHOTOzine for free!
Upload photos, chat with photographers, win prizes and much more for free!
I disappeared off into town this morning - came home for lunch and since the weather was so nice went off into town again. This time with the intention of stopping by the Millennium Bridge - which I call the Waitrose Bridge - to take a few pics.
Perfect timing - 15 minutes later the blue sky and sunshine had disappeared but not before I got the pics I wanted
I've just been watching Blade Runner and a few new ideas come up with - nothing remotely Blade Runner like however - possibly more to do with the vodka I've just drunk
Like this one, just proves symmetry can work
Look forward to the vodka inspired 'non blade runner' ideas.....
Quote: Nice shot Alison, love the sky. I might have been tempted to use the clone tool to tidy the bridge floor though.
I may well do that yet - when I've finished trying to tidy the house up a bit
Quote: Look forward to the vodka inspired 'non blade runner' ideas.....
The first of the vodka inspired ideas might be a failure - I have two more though
ePHOTOzine, the web's friendliest photography community.
Upload photos, chat with photographers, win prizes and much more.


text:
The Larry Joe Taylor Texas Music Festival in Stephenville is April 20th Thru the 25th
Larry Joe Taylor's Melody Mountain Ranch has become a hot spot for the biggest names in Texas Music.
Here's a look at who is coming this year: Gary P. Nunn, Casey Donahew Band, Delbert McClinton, Deryl Dodd, Turnpike Troubadours, Cooder Graw, Jason Boland & the Stragglers, Cody Canada, Mike McClure, Randy Rogers Band, Ray Wylie Hubbard, Kevin Fowler, Brandon Rhyder, Zane Williams, Mike Ryan, Luke Wade, Josh Abbott Band, Cory Morrow, Tejas Brothers, Roger Creager, Charlie Robison, Mark McKinney and many more.
Larry Joe Taylor's Texas Music Festival
Dates and Times
- April 20th – 25th, 2015.
- Gates 10am
- Entertainment 11am – Midnight daily
Melody Mountain Ranch, 1290 County Road 707 Stephenville, TX 76401
Purchase Tickets online.
- One day pass $20.00 in advance
- One day pass $27.00 at the gate
- Five day pass $86.00 in advance
- Five day pass $105.00 at the gate
- Five day reserved seat on West stage with backstage pass $495.00
More Info.
- Call LJT Music Festival offices at (254) 968-8505.
- Camping sites available early
- Campers move in Monday, April 20th, 2015
- Four and Five day tickets are subject to availability
- For the entire lineup visit Larry Joe Taylor's website
- Chili Cook-off registration can be done online. C.A.S.I. Rules apply


text:
Acceptances / Any Yale admits get the acceptance package yet?« on: February 12, 2006, 05:03:51 PM »
Forgive me, I've been out of the loop. Have any of the YLS admits received their acceptance package yet?
Show Posts
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Topics - Raskolnikov
Acceptances / Any Yale admits get the acceptance package yet?« on: February 12, 2006, 05:03:51 PM »
Forgive me, I've been out of the loop. Have any of the YLS admits received their acceptance package yet?
Law School Applications / Still no word from NYU EA...« on: January 01, 2006, 04:08:25 PM »
Anyone else still not hear back yet? Yes yes, I've gotten in to great places, but I wrote two scholarship essays for NYU and would like to see how those turned out. Shouldn't I have at least heard a yes or no by this point?
Acceptances / In. At. Yale.« on: December 19, 2005, 04:19:53 PM »
My heart just stopped.
Just got the call.
Not kidding at all, I'm freaking out.
Law School Applications / Any other Harvard admits still not hear back from UVA?« on: December 02, 2005, 10:51:00 AM »
Not that it's keeping me up at night, but a large scholarship offer could make me take a pretty close look.
Law School Applications / Waiting for Harvard« on: November 23, 2005, 11:50:42 AM »
Anyone else get anxiously excited every time their phone rang yesterday? Last year the first acceptances were the Tuesday before Thanksgiving. They're one day behind! I heard from Toby once already, and the fact that I'm not auto-admit material makes me more anxious than if I had numbers like, say, veeleigh's.
Law School Applications / Application today, fee waivers tomorrow?« on: September 13, 2005, 04:04:27 PM »
I have every application locked and loaded, but it's possible a number of the schools I'm applying to will send me waivers over the next few weeks. Is it a pain in the ass to submit and pay for apps today, then get reimbursed after I receive those waivers? I just want to have it all behind me so I can focus on my job.
Law School Applications / Question for those who have already submitted an app« on: September 08, 2005, 12:50:03 PM »
So I just submitted my first application via LSAC, using a fee waiver, but it prompted me to order a $12 LSDAS report, since I'm registered but had not yet ordered one.
Anyway, do I have to order a $12 report for every online application I submit? I thought that the school would just request the LSDAS report, but I ordered this first one just to be sure I wasn't doing something wrong. What's up with this?
Personal Statement / Does UChicago request/allow a supplementary essay?« on: September 04, 2005, 08:22:43 PM »
Maybe I didn't read the instructions well enough, but it seemed unclear. Can I attach my supplemental essay to the LSAC application?
Law School Applications / Catholic Libertarian = Diverse?« on: September 01, 2005, 11:43:23 AM »
So I'm probably going to write about wanting to do a JD/PhD for my diversity essay, but after telling a friend who went to Notre Dame that I'm both Catholic and libertarian, he said he was surprised because most Catholics fall into the social conservative anti-abortion crowd or the social justice just-war crowd. So would writing about being a strong Catholic and a libertarian, and not seeing the two as inherently conflicting be an adequate diversity statement? Or should I stick with the JD/PhD topic?
Personal Statement / My last PS review request (no really!)« on: August 20, 2005, 02:45:05 PM »
Anyone mind giving it a read? I think I'm close to complete, but I'm worried that after taking my prof's advice and moving from 90%/10% personal/academic to 60%/40% may have hurt the flow. Thanks in advance!


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A man whose dog was shot and killed by a Filer police officer has hired a lawyer. Rick Clubb says he has hired Boise attorney Nate Peterson to represent him.
Peterson says Clubb's Fourth Amendment rights, the protection from unreasonable search and seizure, were violated when Officer Tarek Hassani shot and killed Clubb's dog, Hootch. Peterson calls Hassani's actions a case of "gross misconduct."
Many in the small town of Filer agree. They're expected to turn out to support Clubb at tonight's city council meeting. That's despite the fact council members say they will not discuss the shooting until an independent review by the Nampa Police Department is done.
Officer Hassani is on paid administrative leave tonight pending the outcome of that investigation.
Hassani is the only person named in the suit, but Clubb's attorney says that could change.
One supporter of the officer says he believes Hassani was justified in the shooting and has seen Clubb's dogs act aggressively.
- Latest


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Highland Hills Golf Course
- 2075 Oakland, Highland, MI 48356
- (248) 887-4481
|18 total holes at facility
|Green fees - $7 to $35 (estimate)
|Built in 1926
|Driving Range: Yes
|Public golf course
Highland Hills Golf Course is an 18-hole regulation length golf course in Highland, Michigan. This short layout will reward good shots and provide a fun golf outing for everyone. Online tee times may be available at Highland Hills Golf Course or at nearby golf courses, usually offered at a discount from the normal rate.
|Course Rating
|Back Tees
|Course Superintendent: Robert Stadler
|Manager: Carol Jacobs
Note: The information is typically accurate, however, sometimes there will be errors. If you happen upon anything that should be updated, please let us know.
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July 8, 2014
Star News
Principal to return to court on assault rap
Rasbert Turner, Star Writer
Principal of the Jonathan Grant High School, Dr Oniel Ankle, is scheduled to reappear in the Spanish Town Resident Magistrate's Court on September 2, 2014 to answer to assault charges involving a student.
When the matter came up for mention yesterday, the court failed at getting the complainant's mother to accept mediation in the matter.
It was then put off for a mention date.
It is being alleged that in September last year, the complainant was at school when he reportedly disrespected a teacher at school during a class session.
It was brought to the principal's attention and he allegedly used a piece of plastic pipe to hit the child.
He went home and related what had happened to his mother.
The matter was subsequently reported to the Portmore Police Station and an investigation conducted by Constable Kohan Fuller resulted in the educator being served with a summon to answer to a charge of assault occasioning bodily harm.
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White Paper | August 13, 2014
Why You Need Backup And Disaster RecoverySource: N-able Technologies Inc.
Let's get this out right here at the beginning: at some point down the road, your data is going to be in danger
It could be a machine error. It could be a virus. It could be a tornado the size of Nebraska. But sooner or later, you're going to be in a situation where you're at risk of losing some or all of your data.
Intellectually, you probably believe me. You know that things just fall apart sometimes. And you've probably heard all the shock-and-awe, fear-mongering statistics, statistics like these:
- 90% of businesses losing data from a disaster are forced to shut down within two years. (1)
- The survival rate for companies without a disaster recovery plan is less than 10%. (2)
- Only 44% [of businesses] successfully recovered information after a recent data recovery event. 3)
- 53% of claimants never recoup the losses incurred by a disaster. (4)
So like I said, intellectually you probably believe me. But you don't believe me.
It's not your fault.
Download the full white paper below to learn more.
N-able Technologies Inc.
MORE FROM N-able Technologies Inc.
Contact Details
N-able Technologies Inc.
450 March Road, 4th Floor
Ottawa , ON K2K 3K2
Ottawa , ON K2K 3K2
877-655-4689 ext 304
Derik Belair


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Bucs Didn't Have to Bid Against Anyone But Themselves
When the trade between the New York Jets and the Tampa Bay Buccaneers was announced yesterday, there was some public backlash on the compensation that the Jets received. In the trade, the Jets gave up Darrelle Revis for a first in 2013 and a conditional fourth that could move to a third should Revis stay on the Bucs roster on the third day of the 2014 league year.
While some in the media have panned the Jets on the trade, according to PFT who confirmed this with a source, there was only one team who was in the mix for Revis. This was something anyone who followed the story already knew all too well.
"If we had the luxury of time, if we had the luxury of Darrelle not having been injured, not having gone through rehab, then I think things would be a lot clearer both from our standpoint and in the case of potential trade suitors," General Manager John Idzik told reporters Sunday night on a conference call.
Beyond the injury, beyond the compensatory component, the Bucs were also the only team who knowingly entered a contract with Revis knowing his penchant for holding or at least threatening to hold out. While they are paying him a premium per season, I guarantee that before the end of this deal there will come a time when either Revis feels undervalued yet again or the Bucs feel they are not getting the return on investment. In the end, this was the best deal the Jets and Revis got from any team, mostly because it was the only deal available to the Jets and Revis.


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Procedural Sedation
At Children's Hospital of Pittsburgh of UPMC, we believe parents and guardians can contribute to the success of their child's visit and we invite you to participate. Please read the following information to learn about this medication, its use for your child's surgery, and how you can help.
Fast Facts About Procedural Sedation
Your child's test or surgery will be done under procedural sedation (se-DAY-shun), which means that your child will be given medication to make him or her very drowsy and relaxed during the procedure.
This kind of medication is used when your child does not need to be sound asleep for the procedure, but needs to be very calm for it.
Although not fully asleep, your child will not feel any pain during the procedure.
The doctor doing your child's test will give the sedation medication.
Home Preparation
When sedation is needed, there are important rules for eating and drinking that must be followed in the hours before the procedure. One business day before your child's procedure, you will receive a phone call from a nurse between the hours of 1 and 9 p.m. (Nurses do not make these calls on weekends or holidays.) Please have paper and a pen ready to write down these important instructions.
The nurse will give you specific eating and drinking instructions for your child based on your child's age. Following are the usual instructions given for eating and drinking. No matter what age your child is, you should follow the specific instructions given to you on the phone by the nurse.
For children older than 12 months:
After midnight the night before the procedure, do not give any solid food or non-clear liquids. That includes milk, formula, juices with pulp, coffee and chewing gum or candy.
For infants under 12 months:
Up to 6 hours before the scheduled arrival time, formula-fed babies may be given formula.
Up to 4 hours before the scheduled arrival time, breastfed babies may nurse.
For all children:
Up to 2 hours before the scheduled arrival time, give only clear liquids. Clear liquids include water, Pediayte®, Kool-Aid® and juices you can see through, such as apple or white grape juice.
In the 2 hours before the scheduled arrival time, give nothing to eat or drink.
If your child takes daily medication, you may give it unless specifically told not to do so by your child's doctor or the scheduling nurse.
Getting Drowsy
Once your child has been registered for the procedure, a nurse will meet with you to take your child's vital signs, weight and medical history. As the parent or legal guardian, you will be asked to sign a consent form before the sedation medication is given.
Your child's doctor will decide which type of medication is right for your child, depending on your child's age, medical history and the type of surgery or test being done.
Medication may be given by mouth, through the nose, into the rectum, or directly into a vein through an intravenous (IV) line.
The medication will work in one of two ways: In a single dose that takes effect slowly and lasts throughout the surgery or test, or in a continuous dose throughout the procedure.
You may stay with your child until he or she is very drowsy. You will be taken to the waiting room when the surgery or test is ready to begin.
During the procedure, your child's heart rate, blood pressure, temperature and blood oxygen level will be checked continuously.
Waking Up/Going Home
When the surgery or test is done, you will be called to the room to be with your child as the medications wear off. The length of time it will take the medications to wear off will vary, as some children take longer than others to become alert.
Children coming out of sedation react in different ways. Your child might cry, be fussy or confused, feel sick to his or her stomach, or vomit. These reactions are normal and will go away as the sedation medication wears off.
When your child is discharged, he or she might still be groggy and should take it easy for the day.
Your child may resume normal activities, eating and drinking at the rate he or she is comfortable with when you get home.
A nurse will call you 24 hours after the test to check how your child is doing.
Special Needs
If your child has any special needs or health issues you feel the doctor needs to know about, please call the office of the doctor who will be doing the test before the test and ask to speak with a nurse. It is important to notify us in advance about any special needs your child might have.
Department of Pediatric Anesthesiology
Children's Hospital of Pittsburgh of UPMC
One Children's Hospital Drive
4401 Penn Ave.
Pittsburgh, PA 15224
Last Update
March 26, 2010
March 26, 2010


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Crafted with a flattering mid-rise and a skinny leg, Acne's 'Skin 5' jeans are one of our favorite styles. This perfect-fit pair is cut from comfortable stretch-denim and finished with a cool faded mid-blue wash. Wear yours with everything from wedge sneakers to pointed pumps.
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Product code: 335333 - Need help? Contact us


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The Making of Manila
1975. The Philippines. 22 min.
Manila in the Claws of Light
1975. The Philippines. Lino Brocka. 124 min.
Friday, February 7, 2014, 7:00 p.m.
Theater 3 (The Celeste Bartos Theater), mezzanine, The Lewis B. and Dorothy Cullman Education and Research Building
The Making of Manila
1975. The Philippines. Produced by Miguel de Leon. A newly rediscovered documentary on the making of Maynila, by director Lino Brocka and producer/cinematographer Miguel de Leon. Brocka is seen directing his actors, staging scenes, and discussing his artistic vision and political activism. In Tagalog; English subtitles. 22 min.
Manila in the Claws of Light
1975. The Philippines. Directed by Lino Brocka. Screenplay by Clodualdo del Mundo, based on the novel by Edgardo Reyes. With Bembol Roco, Hilda Koronel, Rafael Roco Jr., Lou Salvador Jr., Tommy Abuel, Lily Gamboa, Jojo Abella, Juling Badabaldo. Lino Brocka's Maynila is a haunting, beautiful landmark of Filipino cinema, and it is thanks to the inimitable Pierre Rissient that it was potentially saved from oblivion. He writes, "There are undoubtedly a few people left who still remember that day in Cannes 1978 when rumors started circulating about a small, low budget film from the Philippines. A 'dirty' film, as some claimed, once more proving Lu Xun correct when he observed that while some art might originate in the sewer, it can be so full of passion that it goes as deep as tragedy. And perhaps even further, because Lino was one of the most physical filmmakers that cinema has ever had. A true fireball, he moved insatiably from one set to rehearsals of Larawan in Fort Santiago where he directed a very dedicated group of actors, then onto a TV set where he would shoot a TV show in addition to a film as good as A Streetcar Named Desire. He possessed a remarkable vitality that was expressed fully in the large demonstrations he organized against Marcos's regime. With the money he made with his commercial films he bought some sophisticated sound equipment that allowed him to cover the entire Epifanio de los Santos Avenue, Manila's massive north to south transportation corridor. Lino knew all the arteries of this swarming city, and he penetrated them just as he penetrated the veins of the outcasts in his films. Sometimes a vein would crack open and bleed. And that blood oozed on the screen with Insiang, Jaguar, Bona, Bayan Ko (My Country), all of which were shown in Cannes. And then, just like that, he died, in a stupid, easily avoidable car accident…. Still, when you watch Manila, you'll be burned by a flame that never goes out." A pariah of the Marcos regime, Lino Brocka entrusted Rissient with the film's original camera and sound negatives, and for more than three decades, the materials were safeguarded by the BFI National Archives. Now, in 2013, we can celebrate an urgently needed digital restoration. Restored in 2013 by the World Cinema Foundation and the Film Development Council of the Philippines at Cineteca di Bologna/L'Immagine Ritrovata laboratory, in association with LVN, Cinema Artists Philippines and Miguel de Leon. Digital projection. In Tagalog; English subtitles. 124 min.
In the Film exhibition MoMA Presents: Lino Brocka's Manila in the Claws of Light
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Motorola Xoom 32GB Wi-Fi Tablet for only $399 [Deal]
Who likes saving money? Today and today only the Motorola Xoom is on sale for $100 dollars off. You can get the 32GB Wi-Fi only model for only $399 ($100 off regular pricing) thanks to our friends over at 1saleaday.com but you better hurry as there is only a few hours left. While this isn't a HP Touchpad for $100 who wants webOS? I sure don't and I'd much rather run Android. You all agree right?


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To the Editor: We are deeply sorrowed by what has recently happened between St. Patrick & St. Anthony Church and Deacon Joe Finnigan.
Many times we have heard his homilies. His thoughts and writings were highly stimulating and we often applauded them. So many people attending worship felt this same way.
Many of the parishioners believe that if he gave a rebuttal on what happened, explaining what drove him to do this (medical bills, needing money to pay other bills, or whatever), it would be explainable in this age of uncertainties.
After retributions are made, we feel the Lord is forgiving. We hope to hear from him.
May God bless Joe and his family, and the Lord forgives him for his sin. He will be missed.
— Robert, Beverly and Michael Albergo/Grand Haven Township


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When I launch the game I get an error "Game Error 122, No Suitable Graphics Device Was Found" and the game never opens, what can I do?
If you receive this message, the primary reason is that your video card may not meet the minimum system requirements for the game.
LOTRO System Requirements
DDO System Requirements
How do I find out what kind of graphics card my computer has?
To determine your graphics card model we would recommend reviewing the information listed under the Display tab in the DirectX Diagnostic Tool or "dxdiag". Info on accessing this is detailed further down in this article but also can be found here.
I believe my graphics card does meet these requirements but I'm still getting the 122 error, what can I do?
If you know your card meets those requirements but the 122 error still comes up, what this usually means is that the game cannot detect certain support for its required features via DirectX and your cards drivers. Contact your graphics card or PC manufacturer to make sure that you have the most updated drivers available for your card installed, and update them where necessary. Older drivers sometimes have limited support for the games features; updating them to the newest available can allow the game to detect support for its settings and launch past the 122 error.
Important Note for users with Intel graphics cards: Intel graphics cards do not technically meet the games minimum requirements because they are not generally designed around 3D gaming so they lack many of the more robust hardware level features of a typical 3d gaming based or discreet graphics card and the game requires many of these features. One of those is the ability to support Hardware Transform and Lighting (T&L) and its lack can cause the game to give the 122 error.
Some models of Intel graphics cards can however emulate this and some of the other features through their drivers in a form of software-based rendering. If the installed drivers do not support this type of emulation though the game can and does give the 122 error. It is recommended that you update to the latest drivers available for your model card directly from Intel in these instances but also keep in mind these cards are not supported and quite often cannot run the game with what is generally considered acceptable quality, performance or stability if the games settings are configured too high.
DirectX says I have an emulated or standard VGA or virtual driver installed for my graphics card, what does this mean?
If you run your computer with any kind of "Virtualization" software (examples are VMWare, Logmein, Remote Desktop) this can cause the 122 error typically because these programs force the system to load a very basic graphics driver that does not utilize 3d features like hardware T&L so the game gives this error. (The game cannot run with a virtual or otherwise emulated graphics driver, if the graphics card meets the requirements but the wrong driver is loaded such as one that does not support 3d gaming the 122 error will occur.)
This can also happen if Windows is in loaded into safe mode, or basically the system has any kind of "Generic" video driver installed that cannot support 3D rendering. If booting into "safe mode", you will need to launch Windows under a normal boot up and verify that the correct drivers for your card are loading.
To find out what driver is being loaded and other key info, launch the "DirectX Diagnostic Tool" (dxdiag):
When the DirectX Diagnostic Tool screen opens, click on the tab labeled Display. There the column on the right will detail the graphics driver information such as driver date, card model, driver version etc.
Use this information to determine:
Most often, updating/reinstalling the drivers will remedy this issue, unless your systems graphics card is not supported.
In some instances, you might need to have the game re-detect and reset its graphics configurations, which can be done by following these steps:
What this does is it forces the game to re-detect the system hardware and configure its default settings appropriately. If the drivers have changed, been updated it should detect this now and no longer give the 122 error.
If you need further assistance, please follow up with Technical Support.
We'd love your feedback and comments on this article! Please rate the article below and then add a comment!


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The Style Gallery is a great new way for you to view, love, and share outfit photos. It's meant to showcase
all the expressive, creative, and inspirational personalities of our community!
Love you too!
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From what we understand, you're looking absolutely adorable in this elephant-printed blouse! A herd of white pachyderms parade across the breezy, navy-blue fabric of this tab-sleeved top, showcasing your playful style with their decorated silhouettes. Styled alongside crimson skinnies and laced, foldover booties, this casual-chic piece is sure to drive all your fashion-loving pals wild!
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PORTLAND (NEWS CENTER) - The Portland Pirates hosted the Worcester Sharks Friday night and beat them by a score of 4-3. Portland goaltender Chad Johnson picked up his 7th win in the game, stopping 27 of 30 shots he faced.
The Sharks came out with a bang. Just 4:17 into the opening period, former Pirate Tim Kennedy got the Sharks on the board first on an aimless that found its way past Pirates goaltender Chad Johnson. Exactly halfway through the period, Matt Irwin of the Sharks was booked for a tripping penalty that sent the Pirates to the power play. Eight seconds later the Pirates would tie it up at 1, when David Rundblad took a pass from Michael Stone and put the puck over the left shoulder of Sharks goaltender Alex Stalock. Rundblad's goal was his 3rd of the year, and third in his last 3 games.
It was just over halfway through the second period when Alexandre Bolduc would break the tie. Bolduc's goal, his team leading 12th of the year, gave the Pirates a 2-1 lead. Chris Brown would follow Bolduc's goal with one of his own, this time on the power play for his 8th of the year. The Sharks would bite back just a couple of minutes later, as James Sheppard would score his third of the season to get Worcester within one. Just 20 seconds after the Worcester goal, Jordan Martinook and Yanni Gourde dropped the gloves. Chris Conner would then capitalize on a Bolduc pass for his 6th of the season to give the Pirates a 4-2 advantage heading into the second break.
The third period began with a Sharks goal. Just 1:51 into the period, Tim Kennedy scored his second goal of the night and his 8th of the season to get the Sharks within one. Worcester would go down fighting, as Bracken Kearns would drop the gloves with Brett Hextall for the second fight of the evening.
The Pirates improved to 9-8-1-1 on the season, dropping the Sharks to 9-8-1-1 on the season. The Pirates win tied the two teams at 20 points, good for 3rd in the Atlantic Division standings. The Pirates also finished ahead in shots by a tally of 37-30. Stalock took the loss and stopped 33 of 37 shots he faced for the Sharks.
The Pirates get back to the ice tomorrow when they face off against the Providence Bruins on Kent Hulst Bobblehead night at the Cumberland County Civic Center, presented by Bath Savings Institution. Puck drop is at 7:00


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While it is easy to get upset by this � after all, a software mod shouldn't void a hardware warranty � that's still Apple's policy and anyone who does tinker with their phone is likely aware of the risk. The blog mentions a very good point that anyone fiddling with the inner workings of their iPhone would do well to remember: reset to defaults if you need to send it back:
So while he eventually got Apple to return the iPhone (after paying the restocking fee, that is), the lesson here is to do a restore of your iPhone and re-install the factory AT&T SIM before bringing into an Apple Store for service. That�s the beauty of software-only hacks, after all!
Truly, you cannot criticize Apple for taking this stance. They sell the iPhone as a hardware and software bundle, and don't intend for it to be taken apart. With modding there is always a risk for the manufacturer to give you the cold shoulder when it comes to an RMA.


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Associate Professor
307B Mudd Hall
Department of Biology
Johns Hopkins University
3400 N. Charles Street
Baltimore, MD 21218-2685
Email: xchen32 at jhu.edu
Office 410 516-4576
Lab 410 516-6543
Departmental fax 410 516-5213
B.S.University of Science & Technology of China (USTC), Hefei, China
Ph.D.University of Texas at Austin, Texas
PostdoctoralStanford University School of Medicine, California
Research Interests
Epigenetic regulation of Drosophila germ cell differentiation from a stem cell lineage
A broad definition for "epigenetic phenomenon" refers to effects on gene expression or function that are heritable through many cell divisions without altering the primary DNA sequences. Epigenetic regulation can act through different mechanisms, including post-translational modifications of histones and localization of the chromatin modifiers to particular subnuclear regions. Failure in appropriate epigenetic regulation may lead to abnormalities in development and may also underlie early steps in cancer genesis.
During normal development, the mechanisms that regulate differentiation of cells from undifferentiated precursors play key roles in tissue/organ development and maintenance, such as gametogenesis. Precursor germ cells must commit to differentiate at the right place and with the right timing to generate and maintain the pools of functional gametes. The maintenance of the precursor germ cells in an undifferentiated and proliferative state and the subsequent reversal of these controls to allow terminal differentiation are both critical to continuous production of gametes throughout lifetime.
The Drosophila male germ line provides a powerful model system for studying the mechanisms that regulate differentiation in adult stem cell lineages. My laboratory utilizes it as a model system to study how genetic and epigenetic mechanisms interplay to ensure proper gene expression during spermatogenesis. We use molecular genetics and genomic strategies to systematically study the following questions: (1) Are there genes with stem cell-specific expression? (2) Is the specific expression of these genes maintained by a unique chromatin state? (3) How do the transcription and chromatin landscape change in continuously differentiating germ cells during normal development? (4) How do the epigenomic changes regulate proliferation versus differentiation processes in this lineage? (5) Can GSCs be regenerated if the differentiation process is reversed? Dramatic changes in the transcriptional program and chromatin landscape of male germ cells offer an excellent system to investigate these molecular mechanisms in vivo.
Epigenetic inheritance in germline stem cell lineage
We investigated epigenetic inheritance during GSC asymmetric cell division (Science 338: 679). It has been known for a long time that epigenetic changes are heritable. However, except for DNA methylation, little is known about the molecular mechanisms of epigenetic inheritance. We found that during the asymmetric division of Drosophila male germline stem cell (GSC), the preexisting histone 3 (H3) are selectively segregated to the GSC whereas newly synthesized histones during DNA replication are enriched in the differentiating daughter cell. The asymmetric H3 inheritance occurs in GSCs but not in symmetrically dividing progenitor cells. Furthermore, if GSCs are genetically manipulated to divide symmetrically, the asymmetric H3 inheritance mode is lost. In contrast to canonical histone H3, the histone variant H3.3 does not exhibit this asymmetric pattern during GSC divisions. Thus, our studies provide the direct evidence that stem cells retain preexisting canonical H3 during asymmetric cell divisions in vivo, which may contribute to maintain their epigenetic memory. We are continuing this exciting project by asking: (1) What are the molecular mechanism and cellular basis underlying asymmetric segregation pattern of H3? (2) What are the consequences of the mis-regulation of such an inheritance mode? (3) Is this asymmetric histone segregation mode used in other stem cells or asymmetrically dividing cells, and is it applicable in other organisms? Our studies will shed light on a long-standing question regarding whether and how stem cells retain their epigenetic memory.
Representative PublicationsPublications related to current work:
Research papers:
1. Eun, S., Shi, Z., Cui, K., Zhao, K. and Chen, X. (2014) A non-cell-autonomous role of E(z) histone methyltransferase to prevent germ cells from turning on somatic cell marker. Science, 343:1513-1516. Featured in Faculty of 1000 Biology.
2. Tarayrah, L., Herz, H-M., Shilatifard, A. and Chen, X. (2013) Histone demethylase dUTX directly antagonizes JAK-STAT signaling to maintain the Drosophila testis niche architecture. Development, 140, 1014-1023. Featured article "In this issue".
3. Eun, S., Stoiber, P.M., Wright, H. J., McMurdie, K.E., Choi, C.H., Gan, Q., Lim, C., Chen, X. (2012) MicroRNAs downregulate Bag of marbles to ensure proper terminal differentiation in Drosophila male germline lineage. Development, 140, 23-30.
4. Tran, V.*, Lim, C.*, Xie, J. and Chen, X. (2012) Asymmetric division of Drosophila male germline stem cell shows asymmetric histone distribution. Science 338, 679-682 (* co-first authors).
Featured in Faculty of 1000 Biology.
5. Tran, V., Gan, Q. and Chen, X. (2012) Chromatin immunoprecipitation (ChIP) using Drosophila tissue. Journal of Visualized Experiments (JoVE), pii: 3745. doi: 10.3791/3745.
6. Cuddapah, S.*, Roh, T-Y., Cui, K., Fuller, M.T., Zhao, K. and Chen, X.* (2012) A Polycomb binding site identified in human T cells acts as a functional Polycomb Response Element in Drosophila.
PLoS One 7(5):e36365 (*co-corresponding authors.).
7. Chen, X.*, Lu, C., Morillo, J., Eun, S. and Fuller, M.T.* (2011) Sequential changes at differentiation gene promoters as they become active in a stem cell lineage. Development 138: 2441-2450.
(*co-corresponding authors.) Featured article "In this issue".
8. Gan, Q.*, Chepelev, I.*, Wei, G., Tarayrah, L., Cui, K., Zhao, K. and Chen, X. (2010) Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq. Cell Research 20(7): 763-783 (*co-first authors).
9. Gan, Q., Schones, D.E., Eun, S., Wei, G., Cui, K., Zhao, K. and Chen, X. (2010) Monovalent and unpoised status of most genes in undifferentiated cell-enriched Drosophila testis. Genome Biology 11(4): R42.
10. Kracklauer, M.P., Wiora, H.M., Deery, W.J., Chen, X., Bolival, B., Jr., Romanowicz, D., Simonette, R.A., Fuller, M.T., Fischer, J.A., and Beckingham, K.M. (2010) The Drosophila SUN protein Spag4 cooperates with the coiled-coil protein Yuri Gagarin to maintain association of the basal body and spermatid nucleus. Journal of Cell Science 123 (16): 2763- 2772.
11. Krishnamoorthy, T., Chen, X., Govin, J., Cheung, W.L., Dorsey, J., Schindler, K., Winter, E., Allis, C. D., Khochbin, S., Fuller, M. T., and Berger, S. L. (2006) Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis.
Genes and Development 20: 2580–2592.
12. Chen, X., Hiller, M., Sancak, Y. and Fuller, M. T. (2005) Tissue specific TAFs counteract Polycomb to turn on terminal differentiation. Science 310: 869- 872.
This paper was reviewed by Ringrose, L. in BioEssays (2006) 28:330-334; and featured in Faculty of 1000 Biology.
13. Hiller, M., Chen, X., Pringle, M.J., Suchorolski, M., Sancak, Y., Viswanathan, S., Bolival, B., Marino, S. and Fuller, M.T. (2004) Testis-specific TAF homologs collaborate to control a tissue-specific transcription program. Development 131: 5297-5308.
Review articles:
1. Feng, L.J. and Chen, X. (2015) Epigenetic Regulation of Germ Cells— Remember or Forget? Invited review to Current Opinion in Genes and Development, 31:20-27.
2. Tarayrah, L.* and Chen, X.* (2013) Epigenetic regulation in adult stem cells and cancers. Invited review to Cell and Bioscience, 3:41 (* co-corresponding authors)
3. Tran,V.*, Feng, L.J.* and Chen, X. (2013) Asymmetric distribution of histones during Drosophila male germline stem cell asymmetric divisions. Invited review to Chromosome Research 21(3):255-269 (* co-first authors)
4. Lim, C.*, Tarayrah, L.* and Chen, X. (2012) Transcriptional regulation during Drosophila spermatogenesis. Invited review to Spermatogenesis 2:3, 1-9 (* co-first authors).
5. Chepelev, I. and Chen, X. (2012) Switching splicing pattern during stem cell differentiation. Invited review to Frontiers in Biology, doi: 10.1007/s11515-012-1198-y.
6. Eun, S.*, Gan, Q.*, and Chen, X. (2010) Epigenetic regulation of germ cell differentiation. Current Opinion in Cell Biology 22: 737-743 (*co-first authors).
7. Chen, X. (2008) Stem cells- what can we learn from flies? Invited review for Fly. FLY 2-1: 19- 28.
Selected earlier publications:
1. Chen, X., Zhang, B. and Fischer, J. A. (2002) A specific protein substrate for deubiquitinating enzyme: Liquid facets is the substrate of Fat facets. Genes and Development 16: 289-294. One of the cover stories.
2. Chen, X. and Fischer, J. A. (2000) In vivo structure/function analysis of the Drosophila fat facets deubiquitinating enzyme gene. Genetics 156: 1829-1836
3. Chen, X.*, Li, Q.* and Fischer, J. A. (2000) Genetic analysis of the Drosophila DNAprim gene: The function of the 60-kD primase subunit of DNA polymerase opposes the fat facets signaling pathway in the developing eye. Genetics 156: 787-1795. (* indicating authors of equal contribution.)


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Leave a Review
This was great in a pinch...like them way better than any store bought flour tortillas...as someone else said..it made twice as many as the recipe said...I rolled them thinner..and used more baking (soda or powder..sorry can't remember which is in the recipe..at first they looked a bit thick, but they rolled better than I expected..very good indeed..flag if inappropriate
These were good, basic tortillas. I upped the amt of baking powder & salt, and allowed them to sit covered for 30 minutes before rolling them out, as per others' suggestions. They were very good, just not as great as I remember my friend's nonna's tortillas from childhood. Could it be the oil vs. shortening? I'll try it & report back. Happy eating!flag if inappropriate
Wonderfulflag if inappropriate
I mixed and kneaded the dough in a food processor and it worked great. My yeild was 14 eight-inch tortillas.flag if inappropriate
I enjoyed making this recipe with my friend. He kneaded and rolled and I fried. The tortillas did become a bit tough the next day, but I just reheated them in the oven. They are wonderful!flag if inappropriate
I come from a long line of tortilla makers and I was very dissapointed in your recipe. In our family we do not use a tsp in our recipe because the next day- you end up having one big cracker. We would use one tablespoon baking powder and one tablespoon of salt. And as for the water- we use about 1 1/2 cup to 2 cups depending on how much flour you use and it is always luke warm. We prefer canola oil to anything else and if you want to make flavored tortillas- just add liquid to liquid and dry to dry. Some of our favorites are tomato flavored tortillas- just use a bit of tomato sauce with the water- and pineapple tortillas. We warm them over the burner and serve them with our shish kabobs whenever we have a barbecue. They're great in the morning with scrambled eggs as well.flag if inappropriate
A little tough, but they were resilient enough to make burritos. I rolled them once to about 1/8" thick, separated them with waxed paper and let them rest, then rolled them out as thin as possible just before frying each one. The dough is very stretchy, and I pulled it to help flatten them out.flag if inappropriate
I halfed the recipe (cuz I can) and only had bread flour on hand. But OHMIGAWD, did this really turn out good, added cheddar/jack and fresh cilantro; recooked over cast iron pan and was transported back to Cancun! Very simple, very good.flag if inappropriate
When I found this recipe, I was actually looking for something to use for making wrap sandwiches. It worked well, though I think I will take the other cooks advice and let the dough sit. My finace and my 4yr old had lots of fun helping me with these, and they loved eating them too!flag if inappropriate
I had tried making tortillas before and failed miserably.This time though my tortillas were perfect, I even put a little mexican seasoning in the dough and it was fabulous!My family could not get enough.flag if inappropriate


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Long-awaited Mother localization coming to North America as Earthbound Beginnings
Tucked away in the pre-show leading up to the Nintendo World Championships 2015, Nintendo made an unforseen announcement... Read More
Tucked away in the pre-show leading up to the Nintendo World Championships 2015, Nintendo made an unforseen announcement... Read More
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There's a reason so many people are in love with EarthBound. Sure, you could chalk it up to pure, unbridled nostalgia,... Read More
More Earthbound news may be incoming. Nintendo has added a community especially for the game on its Miiverse social network... Read More
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Developer Experimental Gamer gives you another glimpse at its upcoming RPG Read More
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An original collection of retro-sounding songs is available for free download Read More
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RTEncoder 2.0.0 Released
I am pleased to announce the release of version 2.0.0 of RTEncoder. It is available for immediate download from the Downloads page.
Important Changes Since Version 1.0
RTEncoder has become a commercial product. It is still available for free download, and can decode RTE files without cost. But to encode RTE files requires the purchase of a license.
Major Features in RTEncoder 2.0
- easy to use Wizard style interface for encoding and decoding
- backward compatibility with version 1.0 RTE files for decoding
- supports encoding with up to three key files and one key phrase
- supports strong file encryption via the Blowfish algorithm
- supports compression of the source file prior to encoding for disk and bandwidth savings
- ability to check for an updated version of the software either automatically or manually
- installing a purchased license will unlock features without requiring a new download
Major Website Update
Most of the pages on RTEncoder.com have also been updated with new content reflecting the new release, including a new informational front page and many updated FAQ entries.


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- Filed Under
The refinancing of debt, the expansion of a downtown restaurant/bar and request for a billboard will be considered during this week's open session meeting of the Fond du Lac City Council.
n Council will consider a request from Thomas Sugars on behalf of The Coliseum restaurant/bar for an expansion project that would include a dance floor with D.J. music.
Four people appeared in support of the plan at a recent meeting of the city planning commission; two people appeared in opposition. After its discussion, the commission voted unanimously to recommend the project. Several conditions were ...


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Lighting the candle on the seventh night of Hanukkah, a postcard on the vocabulary of hope and the interconnectedness of two peoples.
A prayer for the poet who doesn't pray. The second in an eight-part series from a photographer and a poet exploring the sacred in the mundane.
The first of eight vignettes by photographer Matthew Septimus and poet Esther Cohen on holy people and holy places that transcend the ordinary.
Although I was born on Christmas, I feel like I'm slightly part Hanukkah now. Each year since I remarried — an event which brought two Jewish stepchildren into my life — I have anticipated the Festival of Lights with almost as much excitement as my hybrid celebration of the Winter Solstice/Yule and Christmas.
My stepchildren are actually half-Hanukkah and half-Christmas; their mother is Jewish, their father is not. Their parents long ago agreed the children would be raised Jewish, so they are attending the several years of Hebrew school that prepare them to become a bar and bat mitzvah. Having grown up with Christian and Jewish extended families, however, they have honored their heritage from both sides by celebrating Hanukkah and Christmas from the time they were born. As each year draws to a close, they look forward to lighting Hanukkah candles as well as decorating the Christmas tree with their doting, out-of-town Presbyterian grandparents.
Do Christmas ham and potato latkes go together? Can Santa visit as well as Judah Maccabee?" ˜guest contributor Adena Cohen-Bearak reflects on reconciling Chanukah and Christmas.
The dreidel's fascinating roots and origins in gambling give one mother (and rabbi) pause about sending "gold" coins to school. A guest contribution from Rebecca Schorr as Chanukah begins.
One of our own shares her story about the importance of being more intentional in celebrating far from home.
A must-watch performance. And, a rather heart-warming back story from the senior senator from Utah.
Looking to a Jewish tradition found in Deuteronomy of absolving loans as a solution to current debts.


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Recap: Alain Vigneault's Post Game Comments
Alain Vigneault, on Hockey Night Live, made these comments
- "There wasn't a lot of opportunities on both sides throughout the whole game. They were able to capitalize on our mistake and we didn't have a strong enough push back offensively"
- On it being too early still, "at this time, with the personnel that we have available I think we have to play a little closer to the vest, which we did. We only gave them eight scoring chances but they scored four goals so, we need to be better in that area and when we get opportunities to generate offense we need to score."
- On Henrik Lundqvist, "I'm sure if you ask him that he knows he can be better than what he has shown. He needs to be better. From the short time I have been with him I know that he is a true professional, he had a great game in Washington, a great practice and is a hard worker and that is what we will do. We need a better push back when the other team scores the first or second goal against."
- "I'm not quite sure how much better we can be defensively when we only give up eight scoring chances. As low as a number as you are going to get in a hockey game. We can be better, Henrik can be better and we need to do a better job offensively. We were able to keep the puck out in Washington and we needed to do a better job tonight."


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10/23/2012 (2 years ago)
Catholic Online (www.catholic.org)
Muhammad's sexual behavior and his multiple marriages are not the kind of thing we would expect in someone whom was supposedly revealed as a perfect human being and prophet of God. Some of Muhammad's sexual behavior and treatment of women, however, goes even beyond what is unseeming to what is clearly abhorrent under any standard of civility and morality, modern or ancient. The story of Muhammad's relationship with his wife Safiya bint Huyayy ibn Akhtab is one such incident.
Catholic Online (www.catholic.org)
10/23/2012 (2 years ago)
Published in Middle East
Keywords: Muhammad, natural law, safiya, polygamy, concubinage, Andrew M Greenwell, Esq.
CORPUS CHRISTI, TX (Catholic Online) - As we discussed in our last article on Muhammad, the sheer number of marriages and concubines that Muhammad had sexual relations with offers sufficient evidence of a man who did not conform himself to the natural moral law in regard to marriage and family life. Apologists for Muhammad's life find themselves in losing battles trying to justify this aspect of their alleged prophet's life.
As we mentioned in our last article, Muhammad lived a life of clear monogamy with his first wife Khadija, but after her death engaged during the last ten years of his life in relationships with other women of a variety of categorizations, but all of which have one common denominator: Muhammad had sexual access to these women.
According to the Islamic scholar Montgomery Watt, Qur'an 33:50 (a supposed revelation which addresses Muhammad's unique law of marriage and sexual relations separate and apart from the law of marriage allowed to Muslims in general), describes a number of categories of women who were sexually allowed to Muhammad. These included: (i) wives for whom Muhammad paid ujur [dowry or hire] (ii) those "whom your right hand possesses--whom Allah has given to you," meaning captives of war or slaves, (iii) the daughters of paternal and maternal uncles and aunts (i.e., cousins), (iv) those who emigrated with Muhammad, (v) believing women who gave themselves to the prophet, provided the prophet wanted to marry them, and (vi) a privilege special for Muhammad apart from the other believers, the khalisatan la-ka min dun al-mu'minin.
Muslim apologists defend Muhammad's multiple sexual relations by arguing that he was not motivated by lust, but rather by pure motives. This seems disingenuous in light of the evidence to the contrary. According to Muslim sources, Muhammad seems to have been afflicted with a voracious sexual appetite or perhaps merely delusions associated with it. It is hard to tell, and the sources appear to conflict. Either way it is unseemly.
For example, we might cite to the hadith evidenced in Sahih Bukhari and related by Muhammad's wife 'A'isha : 07.71.660: "Magic was worked on Allah's Apostle so that he used to think that he had sexual relations with his wives while he actually had not . . . ."
There is evidence, however, that there was something that mere magic here and mere delusions. In Sahih Bukhari (01.05.268) we read: "The Prophet used to visit all his wives in a round, during the day and night and they were eleven in number. I asked Anas, 'Had the Prophet the strength for it?' Anas replied, 'We used to say that the Prophet was given the [sexual] strength of thirty (men).' . . . ."
There is further evidence that Muhammad lacked control in the area of the sexual urges. Three hadith found in Sahih Muslim suggest impulsivity. As reported by Jabir, Muhammad once saw a woman who sexually fascinated him and captivated his heart, "retiring in the shape of a devil." So he went home to his wife Zainab as she was tanning leather and had sexual intercourse with her to relieve himself of his desire. His instructions to his Companions were that when any of them were to have such an urge he "should come to his wife, for that will repel what he feels in his heart." 08.3240, 08.3241, 08.3242.
Muhammad's sexual behavior and his multiple marriages are not the kind of thing we would expect in a perfect human being and supposed prophet of God. Some of his sexual behavior and treatment of women, however, goes even beyond what is unseeming to what is clearly abhorrent under any standard of civility and morality, modern or ancient. The story of Muhammad's relationship with his wife Safiya bint Huyayy ibn Akhtab is one such incident.
Safiya was a seventeen-year-old Jewess who lived in the town of Khaibar with her husband Kinana bin al-Rabi' bin Abu'l-Huqayq. After Muhammad's troops captured the city of Khaibar, Muhammad ordered Kinana to be tortured to death to make him reveal where the treasure of the town was kept. (For those who might be curious, no doubt with the instructions or approval of Muhammad, Khaibar was tortured by having a fire lit on his chest and then killed by decapitation.) (Ibn Ishaq, pp. 515-17)
According to the Muslim biographer of Muhammad Ibn Ishaq, after Muhammad and his followers captured the town of Khaibar, Safiya would have been led past the bodies of her Jewish tribesmen, which would have included the mutilated and decapitated body of her husband, Kinana. Safiya displayed tremendous control and behaved stoically, unlike her cousin whose sorrow so consumed her that she was inconsolable, and Muhammad, irritated by her crying, called her a she-devil and asked her to be taken away from him.
It might be noted that this was not the first time Muhammad had ruined Safiya's peace. Safiya's father, Huyayy ibn Akhtab, had been one of the chiefs of the Jewish Banu al-Nadir tribe. He was, moreover, an implacable foe of Muhammad, and he suffered death at Muhammad's bloody hand.
Similarly, her uncle Abu Yasir suffered death at Muhammad's sanguinary policies. Huyayy and Yasir and their tribe, which would have included Safiya, had been forced to emigrate from Medina and settled at Khaibar.
Eventually, Huyayy was captured, taken to Medina, and, bound hand and neck by rope and in a tattered flowered robe, put to death (by decapitation) along with between 600 to 800 of his fellow tribesmen. Safiya's relationship with her father and her uncle had been close, as based upon her testimony, she was the favorite of both her father and her uncle.
According to Sahih Bukhari 2.14.68, Safiya was captured at the battle of Khaibar and allotted to Dihya al-Kalbi, but the nearly sixty-year-old Muhammad made arrangements to have this young, attractive seventeen-year-old to be given to him, apparently being struck with her great beauty. (See Sahih Muslim 8.3329, Sahi Bukhari 3.34.437)
Safiya, in fact, is an example of how Muhammad had different categories of relationships with women. Originally, his sexual rights over her were as a result of her being a captive of war. She was one of those whom his right hand possessed. Qur´an 33:50. Subsequently, she became one of Muhammad's wives, apparently his ninth, her freedom or manumission being considered the dowry or mahr since all her family was slain and so no one could pay her dowry. (Sahih Bukhari 5.59.524, 1.8.367) Although it is not clear when Muhammad married her, it was shortly after his conquest of the town of Khaibar. This means that he would have had sexual relations with Safiya by right of capture prior to that marriage and while the death of her husband and his beheaded and burnt corpse was fresh on her mind.
It is impossible to believe that the seventeen-year-old captive Safiya engaged in sexual relations with the nearly sixty-year-old Muhammad, murderer of her father, her uncle, her husband, and her male kinsmen of her own free will and happily. It is not likely that her marriage (and her conversion to Islam) was much of a choice either. These were survival tactics of a woman who had no real choice. Muhammad's behavior toward Safiya is nothing less than exploitative and clearly a form of rape.
Indeed, Ibn Ishaq relates how there was initially some fear for Muhammad's life from this relationship, though Muhammad seemed oblivious to it. On the night of her marriage to Muhammad, the faithful Abu Ayyub stood guard outside the tent of Muhammad, and when Muhammad saw him and inquired why Abu Ayyub did so, the latter replied: "I was afraid for you with this woman for you have killed her father, her husband, and her people, and till recently she was in unbelief, so I was afraid for you on her account." (Ibn Ishaq, pp. 241-42). Had Safiya loved Muhammad, or had she been pleased with her situation, whence this fear on the part of Abu Ayyub?
Particularly abhorrent is Muhammad's self-justification, nay, self-adulation regarding his treatment of Safiya. Apparently, the nearly sixty-year-old Muhammad believed that in emancipating the seventeen-year-old Safiya (a woman whose father, uncle, and husband he had caused to be killed, whom his men had captured, and whom he then traded for and treated as a captive over whom he had sexual rights) and in marrying her he was building himself two rewards in Paradise.
Abu Musa reported according to Sahih Muslim 8.3327, that Muhammad maintained that he who freed a slave woman and then married her would obtain two rewards in paradise. The self-adulation of Muhammad in his doing wrong is evidentiary of an utterly blind conscience and an errant, perhaps narcissistic personality.
Poor Safiya who was forced to satisfy the sexual yearnings of Muhammad, the slaughterer of her father, uncle, husband, male kinsmen and tribesmen, and the captor and trader of her female cousins and friends, who handed them out to his minions as if chattel. But-when it comes to female "booty"-Allah knows best, Alahu 'a'lam, the natural law notwithstanding.
Andrew M. Greenwell is an attorney licensed to practice law in Texas, practicing in Corpus Christi, Texas. He is married with three children. He maintains a blog entirely devoted to the natural law called Lex Christianorum. You can contact Andrew at email@example.com.
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