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23rd February 2005
DNA of the tissue destroyer
Genome clues to amoebic dysentery
Entamoeba histolytica, the genome sequence of which is published today (24th Feb 2005), crawling (top to bottom) on the surface of a culture tube and eating bacteria. [John Williams, LSHTM]
Each year, there are an estimated 50 million cases of amoebic dysentery, causing up to 100,000 deaths, mostly in developing countries. On Thursday 24 February 2005, researchers at the Wellcome Trust Sanger Institute and their colleagues reported in Nature magazine the genome sequence of the parasite that causes the disease, Entamoeba histolytica.
A striking new picture emerges of an organism adapting itself to life as a parasite of the human gut. It seems to have jettisoned many genes required for independent survival, relying instead on us, its human host, to help it out. At the same time, it appears to have picked up genes from bacteria in its environment - genes that allow it to use a wider range of sugars and other energy sources.
Dr Matt Berriman, Project Leader at the Wellcome Trust Sanger Institute, said, "The results give a fascinating glimpse of how this ancient parasite evolved and highlights unusual metabolic processes that may be exploitable as drug targets. The genome is full of enzymes and transporters that could be followed up by experimentation."
E. histolytica is a remarkable organism. Its name derives from the fact that it "eats" tissues (histo-, tissue; lysis, loosen): it also has a voracious appetite for bacteria, which is how it can be grown in test tubes. Amoebic dysentery is caught by ingesting cysts - dormant organisms - from water, food or hands contaminated with human faeces. Inside the gut of human host, the parasite hatches and begins multiplying.
The sequencing of E. histolytica was a collaborative effort led by the Wellcome Trust Sanger Institute and The Institute for Genomic Research (TIGR) in Rockville, MD, USA. The project was supported by grants from the Wellcome Trust and from the National Institute of Allergy and Infectious Diseases (NIAID), which is part of the National Institutes of Health.
The sequence reveals almost 10,000 genes, some of which appear to have been acquired from bacteria. Nearly one-third of the genes are unrelated to genes in public databases.
"Entamoeba histolytica is a major cause of acute diarrhoea in developing countries, but the research community working to combat it is relatively small," continued Dr Berriman. "The draft sequence provides a much-needed boost, and our continuing efforts to improve our understanding will strengthen these efforts."
A defining feature of E. histolytica is its voracious appetite - it lives in an environment where it is surrounded by and eats bacteria. In the human gut, it causes diarrhoea, fluid and salt loss and bleeding from the gut. It can also invade the gut wall and spread to other tissues, causing more serious disease.
"Clearly, this amoeba has genes that allow it to sense certain facets of its environment and respond to those cues," said Neil Hall, a Sanger Institute scientist, now at TIGR, who is the senior author of the Nature study.
It was long considered to be a "primitive" organism - originating from the time that bacteria and more complex organisms diverged in evolution, because it lacks many of the characteristic components of more complex cells. It also has some features typical of bacteria.
One emerging and strengthening picture from the sequence of parasite genomes is the number of genes that successful organisms use to evade our defence mechanisms. E. histolytica has large "families" of genes used to produce its surface coat. It is thought that it may use different coats to prevent detection in the human body for years at a time.
The range of genetic tricks surprised the research team, but also leads to hope. "It is also unusual for so many bacterial-like genes to be used in this way," commented Dr Berriman. "Taken together these findings open up a lot of possibilities for producing selective inhibitors - drugs that affect the organism but don't affect us."
Notes to Editors
A high-resolution image of E. histolytica is available from Don Powell: email@example.com
The paper is published by Nature: Loftus B et al. (2005) The genome of the protist parasite Entamoeba histolytica.
The genome sequence consists of 23,751,783 base-pairs (bp). The 9938 predicted genes average 1170 bp in size and comprise 49% of the genome. No identifiable homologues could be identified for one third of predicted proteins (31.8%) from the public databases
For 96 genes the authors conclude that the current evidence is most consistent with gene transfer from prokaryotes to the E. histolytica genome.
There are an estimated 50 million cases worldwide of amoebiasis with up to 100,000 deaths annually, making it the second-biggest killer after malaria for a protozoan parasite. About one in ten people infected become ill. [Source]
Participating Centres:
The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
TIGR, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
School of Biology, University of Newcastle, King George VI Building, Newcastle upon Tyne NE1 7RU, UK
Department of Molecular and Cell Biology, Boston University Goldman School of Dental Medicine, 715 Albany Street, Boston, Massachusetts 02118, USA
Departments of Internal Medicine & Microbiology, University of Virginia, Charlottesville, Virginia 22908, USA
Department of Parasitology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan
Division of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Kinderspitalgasse 15, A-1095 Vienna, Austria
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Department of Molecular Parasitology, Bernhard Nocht Institute for Tropical Medicine, Bernhard Nocht Str. 74, 20359 Hamburg, Germany
Zoological Institute, University of Kiel, Olshausenstr. 40, 24098 Kiel, Germany
School of Environmental Sciences, Jawaharlal Nehru University, New Delhi 110067, India
Unite de Biologie Cellulaire du Parasitisme, INSERM U389, Institut Pasteur 28, rue du Dr Roux 75724, Paris Cedex 15, France
Department of Biochemistry, Bose Institute, P1/12 CIT Scheme VIIM, Kolkata 700054, India
Department of Zoology, The Natural History Museum, Cromwell Road, London SW7 5BD, UK
Center for Biological Sequence Analysis, Technical University of Denmark, Building 208, DK-2800 Lyngby, Denmark
Departments of Internal Medicine, Microbiology, and Immunology, Stanford University School of Medicine, Stanford, California 94305-5107, USA
Publication details
The genome of the protist parasite Entamoeba histolytica.
Nature 2005;433;7028;865-8
PUBMED: 15729342; DOI: 10.1038/nature03291
The Institute for Genomic Research (TIGR) is a not-for-profit research institute based in Rockville, Maryland. TIGR, which sequenced the first complete genome of a free-living organism, has been at the forefront of the genomic revolution since the institute was founded in 1992. The Institute's scientists conduct research involving the structural, functional, and comparative analysis of genomes and gene products in viruses, bacteria, archaea, and eukaryotes.
TIGR Media Contact: Robert Koenig, Tel 001 (301) 795-7880, Email firstname.lastname@example.com
The Wellcome Trust Sanger Institute
The Wellcome Trust Sanger Institute, which receives the majority of its funding from the Wellcome Trust, was founded in 1992. The Institute is responsible for the completion of the sequence of approximately one-third of the human genome as well as genomes of model organisms and more than 90 pathogen genomes. In October 2006, new funding was awarded by the Wellcome Trust to exploit the wealth of genome data now available to answer important questions about health and disease.
The Wellcome Trust and Its Founder
The Wellcome Trust is the most diverse biomedical research charity in the world, spending about £450 million every year both in the UK and internationally to support and promote research that will improve the health of humans and animals. The Trust was established under the will of Sir Henry Wellcome, and is funded from a private endowment, which is managed with long-term stability and growth in mind.


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RAL Space's Solar Physics Group is a cornerstone of UK solar physics research, providing an established, world-leading research programme with observational and scientific leadership over a wide range of key areas. The basic underpinning experimental expertise of the group is solar atomic spectroscopy, for the derivation of solar plasma diagnostics.
The group has a long heritage, including the NASA Solar Maximum Mission (link opens in a new window) (1980-89) the CHASE Spacelab 2 (link opens in a new window)experiment (1985), the Japanese Yohkoh mission (1991-2001), and the NASA SOHO (link opens in a new window) mission.
The group has major hardware roles in the NASA STEREO (link opens in a new window) and the Japanese Hinode (link opens in a new window)missions and studies are underway for a RAL-led instrument for the ESA Solar Orbiter (link opens in a new window).
The Group was involved in the SDO (link opens in a new window)mission; the first of NASA's Living with a Star Programme and also in some smaller projects such as the RESIK instrument aboard the Russian Coronas spacecraft and the NASA SERTS and EUNIS rocket experiments.
The bulk of the research effort over the last few years has been underpinned by observational work using the SOHO spacecraft and in particular the RAL-led Coronal Diagnostic Spectrometer (CDS) and more recently, the STEREO and Hinode observations.
Specific research areas include studies of fundamental processes in the solar atmosphere, research into solar mass ejection processes and flares and plasma diagnostic techniques.
For more information:

subset: commoncrawl


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PIC: Bikini-Clad Selena Gomez Straddles Justin Bieber
Bring on the PDA parade!
Selena Gomez and Justin Bieber weren't shy about showing off their affection while vacationing in Maui, Hawaii on Thursday. After exchanging several kisses on a jet-ski and holding hands on the beach, a bikini-clad Gomez, 18, jumped into her boyfriend's arms and straddled him on the beach. See more photos of their beach PDA.
Their fun in the sun continued when the Wizards of Waverly Place star and Bieber, 17, went parasailing later that afternoon. Still, Bieber -- who recently got an ace of spades tattoo on his left forearm -- didn't exactly feel like a daredevil during the excursion.
PHOTOS: Inside Justin Bieber's workout
"1,200 feet in the air...not the best feeling," he tweeted.
PHOTOS: Celebs' wackiest PDA moments
The lovebirds flocked to the Aloha State on Monday, just one day after Bieber picked up several trophies at the Billboard Music Awards in Las Vegas.


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Visual C# resources
Visual C# is modern, high-level, multi-paradigm, general-purpose programming language for building apps using Visual Studio and the .NET Framework. C# is designed to be simple, powerful, type-safe, and object-oriented. The many innovations in C# enable rapid application development while retaining the expressiveness and elegance of C-style languages.
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'Contemplation and The Cloud of Unknowing: Meditation in the Christian Tradition' with William Meninger, OCSO
|Event Start Date
|Wednesday, November 19, 2014
Founders Chapel
|Event Start Time
|7:00 pm - 8:30 pm
|Cost: Free
"Contemplation and The Cloud of Unknowing: Meditation in the Christian Tradition"
When Father William Meninger encountered a dusty little book in the abbey library called The Cloud of Unknowing, he was delighted at what he discovered. The anonymous 14th century book presented contemplative meditation as a teachable, spiritual process enabling the ordinary person to enter and receive a direct experience of union with God. Written by a monk with practical advice for ordinary people, this spiritual classic maintains its relevance for anyone seeking to learn more about meditation and prayer. Consider joining us afterwards for Mass for Peace in Founders Chapel at 9pm.
Father Meninger is a Trappist monk and retreat master at St. Benedict's Monastery in Snowmass, Colorado. He takes a limited time each year from his silent monastic life to travel the world and teach contemplative prayer. His book, The Loving Search For God is an effort to bring the message of The Cloud of Unknowing to men and women of the 21st century. He is also known for his books on forgiveness and the Enneagram.
|Sandee Gutierrez | email@example.com | (619) 260-4784
|Web Address


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CREATION – Gond master Bhajju Shyam brings together myths of origins, transformation and ending in ten stunning and sequential images in this sumptuous handmade book.
BETWEEN MEMORY AND MUSEUM – A radical, visual perspective on museum studies — where the gaze is reversed, and the museum's subjects reflect on the institution.
I LIKE CATS – A gallery of irresistible feline characters from some of the best-known tribal and folk artists of India.
8 WAYS TO DRAW AN ELEPHANT – A happy introduction of eight different Indian folk and indigenous art styles to children.
THE BOY WHO SPEAKS IN NUMBERS – A brilliant, poignant and darkly humorous fable about children in wartime, set in a Sri Lankan refugee camp.
TREE MATTERS – First-ever book featuring Bhil art that explores an indigenous community's lived relationship to the environment.


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Posted: Wednesday, June 13, 2012 9:26 PM
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• Location: Omaha, Omaha , Ne.
• Post ID: 3836446 omaha


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Documentation, tools, and sample code for developing Windows Media Center applications and services.
The Office 2000 Service Pack 3 (SP3) provides the latest product updates to Office 2000 and offers you the highest levels of performance and security available for Office 2000. It can be installed by enterprise, small business, or individual users.
Windows Embedded Compact 7 Evaluation Edition toolkit is valid for 180 days from the day of installation.
January 2011 Update to the Windows Phone Developer Tools providing bug fixes, a new emulator, and utilities. This update is composed of two installation files and includes the contents of the deprecated October 2010 Update.
The download is installed after the installation of Visual Studio 2005 SP1 and updates the Smart Device Development components in Visual Studio 2005 SP1 with the SQL Server 2005 Compact Edition design time UI/Dialogs, device CAB files, and includes new features like Click Once support.
Documentation, tools, and sample code for developing Windows Media Center applications and services.
Microsoft has provided a version of the WinFX Runtime Components for the general public.
This update provides new tools, application updates and bug fixes for Windows Embedded Compact 7
Power Suite for Windows Embedded Compact Platforms is a group of tools to help developers debugging and testing their code on Windows Embedded Compact Platforms.
PBDA Tools Package consists of the following: PBDA Transport Stream Analyzer, PBDA MCML Server Sample, and PBDA-IP API Tuner Validation Tests
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Zhiyan Yang '13
Tell us about your international journey.
I came to America for the first time as a Freshman of Sarah Lawrence College. As it turns out, it is a life-changing decision for me. Before Sarah Lawrence College, I spent twenty years or so almost exclusively in two cities: Hangzhou and Shanghai, China. I went to Hangzhou Foreign Language School for my high school and Shanghai Institute of Foreign Trade for college for two years before I made my mind to start over my college career in America.
What made you want to attend college in the U.S.? What, if any, concerns/challenges/opportunities did this present?
I quit my college in China because it seemed to be a dead end for me. The education there was not bad, but it was not the right one for me. I was studying economics there but everything I studied was supposed to prepare me for a career in either finance or economics later. Comparing to the undergraduate education in China, I figured that college in the U.S. would give me more freedom to explore my true passions, namely, architecture, history, art, and writing. At the stage of applying, I faced all sorts of challenges. For example, I had to fly to Hong Kong and Singapore to take standardized tests, since they were not offered in Mainland China. I also had a difficult time finding accurate and useful information about U.S. colleges. I think today things have changed considerably, as more students from Mainland China have managed to come to the U.S. and cultural and educational exchanges have been much more effective and vibrant than ever.
How did you learn about Sarah Lawrence College?
I went to an art exhibit of Yoko Ono in Shanghai and was deeply impressed by it. I was amazed by her creativity and her eloquence of expressing herself in the visual form. I was curious about the education she received so I did some research. After that I was further convinced by the kind of liberal arts education offered by SLC.
What made you choose to attend SLC?
Among the colleges that admitted me, SLC seemed to be the most competitive one for various reasons: a generous financial package, its strong curriculum and faculty, and its vicinity to the cultural vibrancy of New York City.
What were your areas of concentration?
I started out studying architectural history and theory with my don, Professor Joseph Forte, and was greatly impacted by his way of thinking, not to mention his incredible knowledge and passion towards art and architecture. I have been studying art history and cultural anthropology ever since, hoping to be able to treat history poetically and critically at the same time. Besides my main concentration, I spent two years studying Japanese language, taking two years of analog photography with Joel Sternfeld, and a semester of Chinese Women's history with Kevin Landdeck. I also managed to audit some of the very interesting classes here, including Oyama Sayuri's Japanese Literature, and Malcolm Turvey's Film Theories. In my junior year, I went abroad to the SLC Oxford program. I was able to spend my year at Oxford University. Both the academic and cultural experience proved to be fruitful. And it was the year at Oxford that gave me a better idea of what to do next and how to achieve it in my life.
What extracurricular activities were you involved in?
I played on the basketball team for four semesters, and have met some of the most serious as well as passionate people in my college life. I am very glad that I have done it and will be proud to tell my grandchildren that I once played NCAA basketball. Also, I am the founder and was the co-chair of Chinese Table, one of the biggest and most active student organizations on campus.
What was your first-year transition to life at SLC like?
It was not easy. Culture shock and language obstacles made it doubly harsh for a 20-year old who had no previous experiences living in the U.S. before. When looking back, I am glad that all this happened while I was in college because you always get a second chance in college, and both your professors and your friends try their best to understand you and are happy to help you out.
How would you describe your experience at SLC?
I loved it. There will always be a spot in my heart for my memories of SLC.
What is the community like at SLC?
It's an interesting community. The diversity and multiplicity sometimes made the communication and interaction slightly harder. But once you accept that and treat it with an appreciative attitude, you will certainly love what the community has to offer. I learned how to respect differences and make the most out of it.
How about the local community—did you spend a lot of time in the surrounding area? How about New York City?
I enjoy being surrounded by neighborhoods such as Bronxville—a cozy, beautiful town with cute, delicate cafes, restaurants, and parks. Some of my best memories here took place in afternoon strolls in the local area with a film camera in my hands. New York is a different story. Good different. New York always manages to exhaust me, but never my passion and expectation. It's the best city in the world for a 20-year-old. And SLC definitely succeeds in incorporating the city into our college life.
SLC values international students because they bring to campus the richness and excitement of a global perspective. Can you give us some examples of how your perspective made a difference in classroom discussions, etc.?
I was fortunate enough to be able to attend an undergraduate conference for development studies held by SLC in the spring of 2013. I not only presented my own paper on the early Chinese experience of modernity realized through its visual culture, but also had the chance to listen to other people—all of whom are undergraduate students all over the world—to talk about their work and opinions on the issue. It is really encouraging to see our work receiving intellectual respect and it is more than helpful to have our ideas collide and shared.
Where do you see yourself in 10 years?
Luckily, I will start my Ph.D. program in Art History at University of Chicago in the fall of 2013. I will be spending at least six years to complete the degree. Hopefully, I will have my own book published in ten years.
What advice do you have for international students considering SLC?
Don't be afraid to experiment with new things. This is what you are meant to be doing in college. And SLC is clearly a good place to do it!
Apply to SLC


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Tag Archives: Walt Disney World
In The News: Floridians Wait on BP Buyouts, FSU Engineering School, Disney Offers Workers Raise, Craft Brews in Danger
By Claudia Marina on April 21st, 2014 | Last updated: April 21, 2014 at 10:40 am
4 years later, thousands await BP payouts – Since the 2010 Deepwater Horizon oil spill, thousands of Gulf Coast businesses and individuals have filed claims in Florida and are still waiting on reimbursement. Out of the 55,000 claims filed in […]
In the News: Tampa airport, Fantasyland opens, Syrian weapons, Apple Mac production, DeMint resigns
By Kelsey Meany on December 6th, 2012 | Last updated: December 6, 2012 at 2:39 pm
Tampa International to ban parking in arrival lanes – Tampa Bay Times – Tampa International Airport has announced that drivers may be banned from parking int he red and blue arrival lanes while waiting to pick up passengers. The Tampa […]


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Rum Cocktail Recipe
Happy Hour: Turbinado
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The Turbinado is a combination of rum, lime juice, and ginger beer. The recipe calls for demerara syrup, which is simple syrup made with sugar in the raw. I didn't have any raw sugar, so I substituted brown sugar simple syrup, which imparts a slight molasses flavor to the drink. If you're a fan of rum, I would give this refreshing, well-balanced concoction a try. It's wonderful! Here's the recipe.
From Brugal
2 ounces rum (preferably Brugal Añejo)
1 ounce fresh-squeezed lime juice
.75 ounce demerara syrup (simple syrup made with sugar in the raw)
1.5 ounces ginger beer
Dash of Angostura bitters
- In a cocktail shaker, combine the rum with the lime juice and simple syrup. Add ice and shake to combine the ingredients.
- Strain into a highball glass filled with crushed ice. Top with the ginger beer and bitters. Enjoy immediately.
Makes 1 drink.
- Category
- Drinks, Cocktails
- Cuisine
- Other


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Change of Address
Last Updated: February 25, 2011
To File Electronically:
Log into CM/ECF.
Select [Bankruptcy > Miscellaneous].
Note for Trustees: A batch entry is also available to file multiple change of address requests [Bankruptcy > Batch Filings > (enter case numbers) > Change of Address (batch)]. Refer to instructions for batch events.
Enter the case number (e.g, xx-xxxxx).
Select [Change of Address] from the event list.
Skip the Joint Filing screen.
Select the party filer.
Browse to select the Letter/Proof of Service (.pdf file).
Note address change in text box (e.g., debtor or name of creditor).
Verify the final docket text; if correct, click [Next] to submit your document(s).
Note: The Notice of Electronic Filing displays giving you the document number. Copies of this notice are immediately e-mailed to all participants who receive electronic notification in the case.


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Why is thinktech different?
Direct measurement of the brain will revolutionise the brain training market.
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Mattel MindFlex: Flex your Mental Muscle by using the Power of your Mind to Control the Ball.
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The Puzzlebox Orbit: The Brainwave Controlled Helicopter. To pre-order go to Neuroheli.com
Featured Technologies
foc.us is a tDCS headset for gamers
Why are Neuroscience Technologies so important?
Put simply; it will and is changing the world! Among the countless reasons here are just a few:
- Educational
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- Intuitive
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- Encourages mindfulness and a better understanding of mental state and neurofeedback training.
- Encourages a better understanding of our brain whilst improving mental health and agility.
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Recent Technologies
- New EEG dry sensor technologies from NeuroSky. EEG stands for Electroencephalography, it is the method in which tiny electrical signals are collected from brain via passive sensors on the scalp, these signals once amplified, reflect brain activity. The NeuroSky MindWave and MindWave Mobile headsets all have a single senor which rests on the left hand side of the forehead.
- Biofeeback sensors combined with the latest algorithms produce usable brainwave data. Biofeedback is the process of gaining greater awareness of many physiological (human body) functions, primarily using instruments that provide information on the activity of those same systems, the goal being able to manipulate them at will. Some of the processes that can be controlled include brainwaves, muscle tone, skin conductance, heart rate and pain perception.
Biofeedback may be used to improve health, performance, and the physiological changes which often occur in conjunction with changes to thoughts, emotions, and behavior.
- BCI (Brain-computer Interface) technologies are at the forefront of computer science. A brain–computer interface (BCI), often called a mind-machine interface (MMI), or sometimes called a direct neural interface or a brain–machine interface (BMI), is a direct communication pathway between the brain and an external device such a PC, laptop or smartphone.
I've been extremely impressed with thinktech, the posts have been informative and easy to read. I purchased a MindWave Mobile headset and it turned up a day early!! Highly recommended for the busy shopper and anyone into tech gadgets.by P.Oakden
Blog Articles
Visit our existing website thinktechuk.wordpress.com for older posts about neuroscience, brain-computer interfaces, neurofeedback, brainwave entrainment and thought-controlled applications.
International Shipping
Yes we offer international shipping. So far we have dispatched goods as far as: Europe, Argentina, Russia, South korea, South Africa, South America, Sweden, Turkey, Hungary, Romania, Australia, USA…the list goes on!


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Responding to the rising need for pharmacists nationally, and particularly in the South, Philadelphia College of Osteopathic Medicine's Georgia Campus now offers a four-year entry-level professional Doctor of Pharmacy (PharmD) degree program.
Supported by a 110-year tradition of training osteopathic physicians and other health practitioners, GA–PCOM provides a unique inter-professional learning environment where subject-expert and accomplished educators, practitioners and pharmaceutical scientists teach and conduct research in modern and advanced facilities.
The PharmD program provides a comprehensive curriculum designed to develop a generalist pharmacist capable of practicing in many different healthcare environments. During the program's first three years, students split time between the classroom and introductory experiential learning. In the fourth year, it is all hands-on, as students take part in eight five-week clinical rotations, gaining exposure to multiple pharmacy specialty areas and practices.
As part of this professionally-oriented education, students work in state-of-the-art classrooms and teaching laboratories, including a sterile products lab, compounding lab and simulated pharmacy practice lab. Other advanced resources include a Pyxis automated dispensing machine and laminar flow hoods to prepare sterile products using aseptic techniques such as intravenous solutions. Clinical learning and assessment laboratories utilizing simulated patients, and a cadaver anatomy lab, are other resources offered by the program.
This is a real-world, hands-on, cutting-edge pharmacy education – one that prepares pharmacists to hit the ground running, starting day one.
Philadelphia College of Osteopathic Medicine School of Pharmacy's Doctor of Pharmacy program is accredited by the Accreditation Council for Pharmacy Education, 135 South LaSalle Street, Suite 4100, Chicago, IL 60503, 312/664-3575; FAX 312/664-4652, web site www.acpe-accredit.org


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The New York Jets' quarterback situation took another twist late Tuesday with news that the team had agreed to a one-year contract with former Green Bay Packers backup Graham Harrell.
Alex Marvez of Fox Sports reported via Twitter that Harrell will report to the Jets on Wednesday, one day before the team's preseason finale against the Philadelphia Eagles. He will become the fifth quarterback on the roster, joining Mark Sanchez, Geno Smith, Greg McElroy and Matt Simms. His initial role would seem to be No. 3 QB behind Sanchez and Smith.
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Harrell lost the No. 2 job in Green Bay to Vince Young last week following a shaky performance in the Packers' exhibition vs. Seattle. Harrell completed six of 13 passes for 49 yards against the Seahawks' starters. Overall, Harrell was 23-for-42 (54.8 percent) for 169 yards, with no touchdowns and one interception (54.6 passer rating) in the preseason.
The 28-year-old Harrell has attempted four regular season passes in his three-year NFL career, all last season with the Packers. He completed two of them for 20 yards.
With the regular season opener less than two weeks away, New York coach Rex Ryan has still not settled on a starter. Smith (three interceptions) struggled at times last weekend against the New York Giants, and Sanchez is nursing a shoulder injury he suffered in the fourth quarter of that game. He will not play Thursday.
Ryan opened himself up to heavy criticism by pairing Sanchez, his incumbent starter, with the team's backup offensive linemen late in an exhibition. Ryan defended the move, saying it was part of the quarterback competition.


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Welcome to Ignited Software. We design and build great software products, and thats about it.
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We love development on the iOS platform. Both iPad and iPhone devices offer great experiences.
Ruby on Rails
Ruby on Rails is our preferred technology for web application development.
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Electronic Commerce
Spree Commerce is a rich and customisable eCommerce platform. We configure and customise Spree Commerce to our customer's needs.


text: > Now, to the problem -- it's fixed. I was not at home when this was > happening, but my wife was. Well, she called me just as I got on the subway > to tell me that she'd noticed all of the connections into the local power > strip were coming loose -- we have two kittens who love wires. She plugged > everything back in firmly, and it appears to be golden again. have you ever heard the story of the servers going down regularly on friday afternoon? It was the cleaning lady who pulled the plug for her vacuum cleaner. >:->


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Breaking news - Oprah and Tyler Perry are crazy rich! - VIDEO
But then there are times when Oprah's weird side comes out, when that unique connection she so strongly maintains with her audience - both in the studio and viewers at home - is broken in favor of reminders that, oh yeah, Planet Oprah might not be such a crazy notion. The lady probably uses $100 bills to clean her teeth. And, in case you'd forgotten, she and buddies Gayle King and Tyler Perry will remind you, as they did while palling around on Friday's show, on which Oprah retold a super-nauseating story about Perry giving her the most incredibly unnecessary gift a media mogul could ever not hope for.
Bonus footage at the end features Gayle and Oprah using the term "boinking," which is just...so...uncomfortable.)
Wait, Gayle gets a Bentley convertible, too, just for telling Tyler Perry how nice he is?!
In that case, Tyler, PURPLE LOOKS GOOD ON YOU! And, also, I need new glasses!


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Macrophage Infiltration in Human Adipose Tissue
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- How to Read a Study Record
Quantification of macrophage infiltration and characterization of macrophage phenotype in adipose tissue of 60 obese subjects and 20 non obese subjects
|Study Type:
|Study Design:
|Observational Model: Cohort
Time Perspective: Prospective
|Official Title:
|Characterisation of Macrophage Infiltration in Obesity and Its Complications
adipose tissue, visceral adipose tissue, muscle, liver, bowel and stomach
|Study Start Date:
|January 2007
|Study Completion Date:
|October 2011
|Primary Completion Date:
|October 2011 (Final data collection date for primary outcome measure)
Obesity results from a disequilibrium in energy balance and an inability to adapt to lifestyles which encourage increased energy intake and sedentariness. These last years, numerous studies contributed to show that obesity is the pathology of an organ, the white adipose tissue (AT), characterized by a low grade inflammation when it is enlarged. The fact that adipocytes secrete a number of inflammatory factors or "adipokines" has forced several groups to reassess the involvement of the AT in wide range of physiological and pathophysiological processes. Adipose tissue probably contributes to the links between obesity, inflammation and insulin-resistance. Our previous results based on transcriptomics studies, showed that genes encoding inflammatory molecules are mobilized in adipose tissue of obese subjects and that caloric restriction improves greatly inflammatory profile. Our preliminary studies on the morphology of adipose tissue lead us to observe a major infiltration of macrophages in morbidly obese subjects. This project is based on a clinical protocol performed in massively obese subjects (BMI>40 kg/m²), where drastic weight loss is achieved by gastric bypass. This project has several objectives. It will allow us to characterize the infiltration of macrophages in the subcutaneous adipose tissue of 60 obese subjects compared with 20 normal-weight subjects, to study the evolution during surgically-induced weight loss and to compare the infiltration observed in adipose tissue to that of other tissues (visceral adipose tissue, muscle, liver, bowel and stomach). This study will be not only quantitative (number of macrophages) but also qualitative by characterizing the phenotype of macrophages with transcriptomics and immunohistochemical approaches. We will analyze the relationships between morphological characteristics of adipose tissue and clinical and biochemical parameters related to insulin sensitivity. More generally, this project might lead us to go thoroughly into the knowledge of the link between obesity and associated comorbidities, particularly metabolic complications, and to consider novels therapeutic strategies.
|Ages Eligible for Study:
|18 Years to 60 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
Inclusion Criteria:
Obese subjects group :
- Obesity with BMI> 40 kg/m² or obesity with BMI between 35 and 40 kg/M² with comorbidities (OAS, diabetes, hypertension etc…)
- Age: 18-60
Non obese subjects group
- Abdominal surgery planned
- Age: 18-60
Exclusion Criteria:
- Inflammatory disease
- cancer
- stroke
- Drugs (AINS)
Inclusion Criteria:
Obese subjects group :
- Obesity with BMI> 40 kg/m² or obesity with BMI between 35 and 40 kg/M² with comorbidities (OAS, diabetes, hypertension etc…)
- Age: 18-60
Non obese subjects group
- Abdominal surgery planned
- Age: 18-60
Exclusion Criteria:
- Inflammatory disease
- cancer
- stroke
- Drugs (AINS)
Please refer to this study by its ClinicalTrials.gov identifier: NCT00476658
|APHP Hopital Hotel Dieu
|Paris, France, 75004
|Principal Investigator:
|Christine POITOU-BERNERT, MD,PhD
|Assistance Publique - Hôpitaux de Paris
No publications provided by Assistance Publique - Hôpitaux de Paris
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Assistance Publique - Hôpitaux de Paris
|ClinicalTrials.gov Identifier:
|NCT00476658 History of Changes
|Other Study ID Numbers:
|Study First Received:
|May 21, 2007
|Last Updated:
|December 6, 2011
|Health Authority:
|France: Ministry of Health
Keywords provided by Assistance Publique - Hôpitaux de Paris:
macrophage infiltration
ClinicalTrials.gov processed this record on October 09, 2015


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Store leftovers for 5-7 days in the refrigerator.
NOTE: This recipe contains raw egg
|egg(s), organic, pastured
|lemon juice
|dry mustard, (optional)
|garlic clove(s), (optional, for alioli)
|olive oil, extra virgin
|flaxseed oil, (or substitute with additional olive oil)
- Combine raw egg and lemon juice in blender.
- Add 1 drop olive oil and continue to blend on high for 30 seconds.
- Add 2 more drops olive oil and blend for 30 seconds.
- Add 5 more drops olive oil and blend for 30 seconds.
- Continue to slowly incorporate olive oil in small portions (about 1 tablespoon at a time). The consistency of mayonnaise should begin to develop.
- When olive oil is completely incorporated, slowly drizzle flaxseed oil into the blender and continue to blend.
44 Comments
What am I doing wrong? I tried to make this but the consistency won't thicken like mayo? It is still liquidy. Help, I must be doing something wrong.
needs a little vinegar. Thickened up nicely for me but the taste was off
how long will this last in the fridge?
It keeps for 5-7 days, read the darn article!
Do I have to use flax seed oil? Or could I Just use a whole cup of olive oil since I'm out of flaxseed?
I had a consistency problem too, I did go slowly. At first it was working but, then turned to liquid before all was added. I used only olive oil but you did say that Olive oil is perfect to use too. Any ideas. I used a Vita-Mix after awhile of being on it turns hot. Maybe the ingredients were actually cooking.
I think "literate" needs a lesson on being nice. There's enough nastiness in the world without adding to it.
I find making mayonnaise or any kind of aioli comes out best when hand whisked. It takes longer but comes out with the correct consistancy. After combining the egg, lemon juice and mustard ( recipe says optional for this but it acts as an emulsifier, so does vinegar) add oil one drop at a time thoroughly whisking after each drop, once it becomes emulsified you can add oil more quickly, just make sure to completely incorporate the oil before adding more.
omit the egg white, add an additional yolk (free range of course), bump up the lemon juice to 2 tsp, and you have a classic aioli
My KitchenAid Mixer doesn't work for this recipe, but my hand blender does.
decided not to make this when i added it all up and saw that every tablespoon of the finished product will have about 15g of fat. yikes. don't trust myself to not make it and eat half of it in some tuna salad
I have tried many, many times, following directions very, very precisely and have had to pour a huge amount of oil and egg down the drain. I have only had success once but don't know why – I did nothing different. I believe now that there is an element of magic involved. I would pay someone who could teach me how to make mayonnaise. I have never been so frustrated in my life. Please don't tell me to pour the oil more slowly – at this point that is just not possible unless I were to spend a full day making it. I use a Braun hand blender and wonder if that could be a problem – can't think of anything else.
I use a product called Vegenaise, best thing since than "slice bread" haha.
They have a soy free version, seriously since I discovered this product a number of years ago, my life became complete :)
You can find it at WholeFoods, FruitFul Yield, any health food store in the refrigerator sections
Remember that all ingredients, should have the same temperature when making it, so take everything you need from the fridge, out about 1 hour before making it…
I had a lot of trouble getting the consistancy just right. Then I started using an eye dropper to litterally add one drop at a time. First I blend just he egg and lemon juice till frothy, then i put one drop in and blend for about 30 seconds or more, then another drop and blend another 30 seconds or more, I keep doing this for quite a while then I add a few drops at a time, and only when I start to see it thicken a little, I use the dropper to add a stream of oil. When it has thickend up a lot, I slower pour the rest of the oil from the measuring cup. I also use a hand blender. It takes a while, but since I started this method, I have not had to throw anything down the drain.
Is soy free veganaise paleo-friendly? It does have brown rice syrup listed in the paleo-friendly ingredients, but also states 0 sugars on the label. Thanks.
How about Trader Joe's mayo? Made with canola oil. I'm breast cancer (hormone positive) survivor so no soy for me. I love their mayo and would find it much easier than making my own. Especially since I don't use a lot. Love the fact that it also has apple cider vinegar in it.
Does it matter, though, if store-bought mayo has sweetener (of any kind) in it? That's what I'm trying to find out.
Instead of using that much olive oil, would it be safe to use applesauce in place of oil?
My first batch was a flop, I made it in my NutriBullet. Do NOT do this! It gets too hot. I used my blender and if you follow the directions exactly as they are written it will work! I added the garlic, but not the mustard, it has a garlic kick! I love garlic though! Next time I'll add the mustard. Thanks for the great recipe!
I have made this a couple of times. The first time was perfect, the second time not at all. The difference I found was what I whisked it in. For *me* it worked when I used a glass bowl. When I used a steel bowl it didn't incorporate. I wonder if the difference is the glass vs. plastic container for the individual blender. I will have to try it again.
My sister makes it in her thermomix. She also uses macadamia oil, as it is lighter tasting.
Folks, I thought this was a paleo site and yet there are posts about using dreaded CANOLA oil. Please respect us paleos by not posting non-paleo ingredient suggestions. Thanks.
Rob – Why so dogmatic? And besides, if you read the references to the "Dreaded Canola" it is stated that its in response to a medical aversion to other Holy Paleo oils. Its about doing your best not being a perfect Type A.
I finally got mayo to work for me by using an immersion blender – the hand held stick. Place all the ingredients in a small canning jar and place the blender in making sure it touches the bottom. Start blending and you're done in less than a minute. So excited to FINALLY have figured this out after wasting so much oil with other attempts.
Use an emmersion blender, you can mix it all up instantly, no waiting on drops, drops , and more drops. I promise, it'll work like a dream!
Like so many others, this didn't thicken like mayonnaise. Came out liquidy. Thanks for wasting 1 cup of very expensive oil!
To firm up the mayo, just slowly add more oil. It will thicken, I promise.
I use my Vita-Mix and make a new batch of mayo every other week or so.
I use 1 TBLS. white vinegar instead of lemon juice and about 1/8 tsp. sea salt.
After blending these ingredients for about 30 seconds, when adding the oil, I start on variable speed 1 for the 1st minute or so then gradually increase to 3 or 4. I have never had a problem with the mayo not thickening. I use sunflower oil instead of the olive oil, as it is a milder taste. The most important key to perfect mayo is adding the oil very,very slowly. I use a measuring cup with spout.
Solena71's wide-mouth mason jar and immersion (stick) blender method works like a dream. It's no fuss and always works. I didn't have flax oil, so subbed melted coconut oil. Doesn't taste like store-bought mayo, but is yummy.
What food processor do you use for such a small quantity. I have a big food processor and a stick. But nothing small enough for the quantity or that will allow me to add the oil while blending. Help please?


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SilverStripe Developer Directory
Find developers and organisations who develop using the SilverStripe platform.
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Find developers and organisations who develop using the SilverStripe platform.
Coogee, NSW, Australia
Innoweb is an innovative internet company based in Sydney producing high quality, attractive and most importantly usable websites. We not only deliver best possible results, but also aim to give our clients a highly personal service.
Chojnice, Pomorksie, Poland
We are creative studio from Poland, based in Pomorze.We promote companies and brands using a number of effective methods. The philosophy of our business is an individual, brand focused approach to each project. On that basis we choose, prepare and execute specific promotional activities. This way we increase consumer awareness and loyalty to your brand. The highest quality of our products and yo
Brescia, Brescia, Italy
We are a creative studio based in the center of Brescia, Italy. We are focused in graphic design, web, developing and advertising.
Kippenheim, Germany
From Ideas to solutions and beyond. We give you an identity online or revive dead ends.
Delft, Netherlands
XD designers, is a full service design firm, based in Delft, The Netherlands. We build our websites and applications using the Silverstripe Framework.
Tromsø, Troms, Norway
W3spor is a small and innovative web company. We have been working with Silverstripe since 2008, and provide implementation and developement of websites, customizing of the CMS, support and education for webmasters. Together with our design and ISP partners we give our customers a complete webpackage of high quality. We are all educated on master level in informatics and information systems.
St Helier, Jersey, United Kingdom
From Jersey in the Channel Islands, E-scape has been carrying out website design, web development and online marketing since 1997. E-scape follow best practice and using Silverstripe and other Open Source platforms deliver the very highest standard of service to all our clients.
Den Haag, Zuid-Holland, Netherlands
Software developer who loves to work with Silverstripe CMS.
Clervaux, Luxembourg
IT company focused on Web Development, Mobile Development and Business Intelligence
Žilina, Slovakia
Silvermax is a company specialized in SilverStripe programming. Silvermax doesn't make websites for end-customers (customer talk, online marketing, graphics etc.), Silvermax does SilverStripe programming for other web agencies (modules development, themes coding, customization, setup and maintenance). Are you busy? Try us!
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New owner of 1997 F250 4x4 7.3 question about turbo
Im a new owner of a 1997 F250 Ext. Cab 4x4 7.3 with 210k miles
I picked the truck up for $3500 and everything works great. New tires, AC/Heat work great, Upper and lower ball joints replaced last year, all new shocks, ect.
The only issue I am having is this. When I bought it Thursday, the guy told me he put a new tensioner and belt on it. He told me there was play in one of the pulleys and he thought that was causing the noise the truck was making. He said truck makes high pitch noise when you hit 2,000 rpm but not until then. I drove the truck on a test drive and heard the noise and figured it was probably turbo related because the noise was not present at low RPMs, only when the turbo should kick in. I used that as a good bargaining chip and got the truck for what I thought was a good price.
Here is what I have experienced the last two days. In the mornings when it is cool still, I notice the noise has pretty much dissapeared on my way to work. In the evenings when the truck has sat in the sun, and it is 100 degrees down here in TX, the noise is prevelant and kicks in at around 2000 rpms. I think the turbo is stock but I'm no expert. Gonna take it to my mechanic Tuesday but wanted to know if anyone else has experienced this problem. The truck looses some power when the noise starts but after it shifts gears, the noise goes away and power returns. The pulley that he said was loose looks to be the power stearing pulley and it is not that bad and doesn't have a lot of play. I dont think this is the cause but could be wrong.
I am thinking turbo for two reasons: 1. Noise and loss of power only occurs at high RPMs when turbo kicks in. 2. The PO had a superchip 1705 that he said he used a couple times and I think you are supposed to get a performance turbo to run the programmer and this could have caused the turbo to fail.
This is my first diesel and I am using it as a work truck/ ranch truck. I dont want to break the bank fixing it and am driving it daily for now. Is it okay to drive for a while with this problem? Is it really costly to fix? And can I rebuild the turbo myself to fix the problem?
I regularly work on my own engines and change my own oil and do my own maintenance but diesel is new to me. Thanks in advance
Welcome to the forum!
I would remove the intake boot from the breather to turbo compressor and inspect the blades. If the boot is the original orange boot, make sure it is not tearing at the clamps (common). Ford has a kit to update that boot and there are a couple of aftermarket replacements as well (orange boot is not available anymore, hasn't been for a long time). Also check the radial play and axial play of the turbo shaft (maybe the blades are starting to hit the housing???). The turbos can be rebuilt. Ron's Turbo Service has rebuild kits and I'm sure there are other places that sell them too. The SC 1705 shouldn't have produced enough extra boost to cause turbo failure. Cheers!
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CAM and the Pulitzer Foundation for the Arts present a collaborative summer series, featuring film and discussion by select contemporary artists that activates the courtyard shared between the institutions. Directed by Derek Jarman, "Blue," presents a portrait of the filmmaker months before his death from AIDS-related complications and explores the literal and allegorical meanings of the color blue.
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text:
Opened 6 years ago
Closed 6 years ago
#10168 closed enhancement (wontfix)
Easy to update the wrong plugin by accident, if...
|Reported by:
|Owned by:
The usability of the plugin interface in admin can be improved. If you have two plugins beneath each other that are updateable it can happen that you click the wrong link to update while in rush.
Being in rush only means that you do look and click faster. This is a sign that usability can be improved because it is not easy to use.
I can imagine an UNDO feature for the plugin update or the other thing would be posing question if it is really intended to upgrade _that_ plugin.
Attachments (1)
Change History (11)
@Denis-de-Bernardy — 6 years ago
comment:2 @Denis-de-Bernardy — 6 years ago
- Keywords reporter-feedback 2nd-opinion added; developer-feedback removed
- Milestone changed from Unassigned to 2.9
I honestly fail to see how we could improve the above screenshot any further...
The update link could go alongside "Activate | Delete" et al, but that seems a bit wrong.
The screen to enter the FTP Details could contain the package's name, though.
comment:3 @hakre — 6 years ago
An improvement would be to pose an additional question after the click wether or not the plugin should be updated. For a straight visual improvement I do not have an idea.
comment:4 @hakre — 6 years ago
Having the question would mimic the same behaviour as delete. And should not be that hard to integrate.
comment:5 follow-up: ↓ 7 @dd32 — 6 years ago
- Keywords reporter-feedback removed
The screen to enter the FTP Details could contain the package's name, though.
Except not everyone has to deal with that screen.
If people insist on a warning, Then a JS confirm is the only type I'd remotely support.
comment:6 @Denis-de-Bernardy — 6 years ago
- Keywords 2nd-opinion removed
comment:7 in reply to: ↑ 5 @hakre — 6 years ago
- Keywords needs-patch added
Replying to dd32:
If people insist on a warning, Then a JS confirm is the only type I'd remotely support.
That is so not taking care then. As webdev you should ever take the JS=OFF route first and enhance it later. So for those who have JS=ON can save one request.
Infact, before making things complex, just go the same route as delete. For delete there actually is no JS warning. It works pretty straight forward. Because the principle of the implementation of the question is already done with the delete action and the user already knows how to deal with it, it is a strong argument _against_ doing things in a new way here. Like introducing a JS confirm.
comment:8 @dd32 — 6 years ago
My definition of that was a JS comfirm for those with JS, a fallback should always be available for non-js users, but those with js should never see it.
IMO, the UI should make it clearer as to which plugin it is, theres a ticket on that which missed 2.8
comment:9 @westi — 6 years ago
- Owner set to janeforshort
- Status changed from new to reviewing
I think the current implementation of this is clear enough.
Assigning to Jane for a second opinion.
comment:10 @ryan — 6 years ago
- Milestone 2.9 deleted
- Resolution set to wontfix
- Status changed from reviewing to closed
wontfix until we revisit the plugins UI again.


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Reel NW films selected for the 2013 PBS Online Film Festival
The Pacific Northwest will be represented at the second annual PBS Online Film Festival. Three short films from KCTS 9's Reel NW series are among the 25 short films that are featuring in the 2013 festival.
The Reel NW films selected are:
Capsule by Antonio (Tony) Altamirano, about two astronauts struggling to stay alive as their crashed space capsule slowly runs out of oxygen.
Honor the Treaties directed by Eric Becker. The film examines photographer Aaron Huey's work for Native American rights on the Pine Ridge Reservation.
The House I Keep by Jhene Erwin and Jennifer Little, is a story of a woman coming to terms after suffering a miscarriage.
The online festival will be accessible beginning March 4 on all PBS digital platforms, YouTube, and PBS social media channels. Check out the preview trailer.
Cast your vote for the People's Choice Award:
Viewers may vote for their favorite short film in the PBS Online Film Festival from March 4 through March 22. The film with the most votes will receive the People's Choice Award. The winning film will be announced in early April.
Post new comment
- All comments are subject to approval.
- KCTS9.org reserves the right to remove posts, at our discretion, which include inflammatory comments, comments that are off-topic, personal attacks or obscene language, or that are otherwise deemed objectionable.
- By submitting your comment for publication on KCTS9.org, you agree to abide by our terms of service: http://kcts9.org/terms-conditions


text:
Search results in category Health-Pharmacy
Found 11 records | Page 1 of 2
1. Flower Essence Services
in Body / Health / Personal Care by Richard Katz
Flower essences and herbal skin care products. Natural plant remedies made from hand-gathered, certified organic, or wild flowers. Effective for stress, over-sensitivity, confusion, or despondency.
phone: view phone(800)548-0075
fax: view fax(530)265-6467
website: http://www.fesflowers.com
e-mail: send an e-mail
2. Sea Chi Organics
in Body / Health / Personal Care by Sanandra Black
Manufactures high-quality, toxic-free organic skin and hair care products using Kombucha Tea as a natural preservative.
phone: view phone(760)832-9351
fax: view fax(760)320-3088
website: www.SeaChi.com
e-mail: send an e-mail
3. Academy of Oriental Medicine at Austin
in Body / Health / Personal Care by Linda Fontaine
Accredited M.S. in traditional Chinese medicine; Asian bodywork program and medical Qigong. 'Premier faculty in North America. Outstanding curriculum and herbal program.'
phone: view phone(800)824-9987
fax: view fax(512)454-7001
website: www.aoma.edu
e-mail: send an e-mail
4. Teleosis Institute
in Body / Health / Personal Care by Joel Kreisberg
phone: view phone(510)558-7285 ...
website: http://www.teleosis.org
e-mail: send an e-mail
5. CENTERSPACE...Coming into Balance
in Body / Health / Personal Care by Rik Center
Stress and trauma resolution, untangling the emotional and physical body.
phone: view phone(415)771-5456
fax: view fax
website: /www.comingintobalance.com
e-mail: send an e-mail
6. Lady of the Lake
in Body / Health / Personal Care by Shelley Sovola
Online health store. Shop for thousands of cruelty-free products, aromatherapy, bath, books, cosmetics, herbs, intimate aids, nutritional supplements, secure shopping, monthly specials.
phone: view phone(541)469-3354
fax: view fax(541)469-2180
website: www.shopladyofthelake.com
7. Safe Effective Alternatives, Inc.
in Body / Health / Personal Care by Jim Rompel
Manufactures 100% pesticide-free Lice B Gone
phone: view phone(877)730-2727
fax: view fax(618)236-2826
e-mail: send an e-mail
8. Village Green Apothecary
in Body / Health / Personal Care by Marc Isaacson
Our integrative pharmacy, focused on individualized healthy living plans, includes pharmacists, nutritional consultants, an herbalist, and a naturopathic doctor. We offer custom compounding, bio-identical hormones, vitamins, minerals, herbs, homeopat
phone: view phone(800)869-9159 ...
fax: view fax(301)493-4671
website: http://www.myvillagegreen.com
e-mail: send an e-mail
9. Amplify Leadership Ltd.
in Body / Health / Personal Care by Athena Williams-Atwood
Offers 'highly effective' elearning solutions for employees, managers and leaders specifically designed with today's companies in mind.
phone: view phone(415)738-7919
fax: view fax
website: www.AmplifyLeadership.com
e-mail: send an e-mail
10. The Ecology Works, Inc.
in Body / Health / Personal Care by James Burnett
Lasting nontoxic, odor- and stain-free indoor control of dustmites, and fleas, and their allergens. Full line of powerful yet nontoxic detergents too.
phone: view phone(888)353-2649
fax: view fax(772)545-1268
website: www.ecologyworks.com
e-mail: send an e-mail


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Posted: Thursday, March 7, 2013 8:28 AM
Hello Gentlemen, My name is Carly. 405-200-7803 I will only be here for two days. Please call for massage of a lifetime. I will not accept texts, unless I have already talked to you on the phone. Texts will be blocked from calling my phone. $100.00 30 min. $150.00 hour. Thank you, Have a nice day.
• Location: Oklahoma City
• Post ID: 5800714 oklahomacity


text:
#TCFishing: Inlet catches include black drum, pompano
Recent fishing action at the Sebastian Inlet State Park North Jetty suggests that the winter pattern is in full swing there. Black drum to 40 pounds, sheepshead, bluefish, flounder, Spanish mackerel and an occasional pompano can be caught. Sand fleas and clams are the best baits for sheepshead and pomps. Shrimp or fiddler crabs and even pinfish for the drum. Flounder will hit mud minnows and shrimp.
Kadri Benton, of White's Tackle in Fort Pierce, reported that offshore fishing reports are scarce due to the slightly rough conditions on Christmas Day. Inshore, anglers reported trout catches at Harbor Branch and Bear Point. Use live shrimp, artificial shrimp, shrimp-tipped jigs or slow-fished jerk baits. Near the inlet and between the bridges, anglers are catching bluefish, jacks, ladyfish and Spanish mackerel during the incoming tides.
Capt. John Young, of Bites On charters out of Billy Bones, posted photos of Thursday snook catches for a client visiting from Virginia. He said the water temperature in the St. Lucie River was 70.9 degrees and bait was scarce, but jigs around the bridges will catch fish. An unrelated report from Jim Harter, of Palm City, indicated that redfish can be caught up the South Fork of the St. Lucie near mangrove roots and oyster bars.
Capt. Mike Shellen, of Okeechobeebassfishing.com, said speckled perch fishing is hard to dial in on right now. As a result, anglers are scattered all over the lake. Open water anglers are finding good numbers of fish in the Kissimmee River and also well outside the mouth of the river. Other anglers are finding larger-sized specks in the very heavy cover areas where two or three different kinds of cover grow together.
To file a report: Contact Ed Killer at firstname.lastname@example.com, call 772-221-4201, text at 772-285-1666 and follow him on Twitter @TCPalmEKiller.
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Total AG Ratings: 1,428
i know i spelled please w/ a z thats how i spell it
if i had to give this game a score from 1-10 i'll give it a 8 or 9 it's a great game tell me what u think pleaze
5 stars!
i relly like it i can make so meny styles!
made her look just like me :) lolz
i absolutly love this game its one of the best ive played :)
black long sleeve, light pink short shorts, blonde braids black hoop earings and black flats with white designs at the end
kool game
Ginger hair (in bun) yellow shirt with green jacket, grey-brown shorts, and peace sign sneakers ^-^ Beautiful ^-^


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This combo features 24 of our most popular nymphs, packed in a small FishUSA foam insert fly box. These are standard nymphs used by the FishUSA staff on eastern trout streams. This assortment is also good for many western streams and Great Lakes steelhead.We have included common mayfly, stonefly and "generic" patterns that will meet many hatch and stream conditions.Purchased separately, these products would sell for $39.35, your price is $33.95, so you save $5.40! This is a great way to try out our fly patterns.Included in this package is two each of the following:
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Lounge Hostel Carnvale
Hostel Carnevale is situated on principal square surrounded by two fontains and numerous bars and restaurants. It is also at the begining of principal avenue- Korzo where is held the most famous Carnival in Europe.
In the hostel we prepaired for You double and quadruple rooms as well as several dormitorys. For a complete comfor and a feeling of intimacy we secured maximum equipped private bathrooms, so Yo can relax as you are at home.
Simply, You are in the middle of everything and your adventure may begin! We are expecting You!
Check in : 13:00
Check out: 11:00
Cash and Credit Cards for payment of balance
Availability & RatesTo view availability and prices please select dates and click 'Update Dates'
Hostel Facilities & Policies
- 24 hour reception
- Adaptors
- Air Conditioning
- Airport transfers
- Breakfast not included
- Café
- Child Friendly
- Credit Cards Accepted
- Fax Service
- Free City Maps
- Free Internet Access
- Free Wifi
- Hair Dryers
- Hot Showers
- Laundry Facilities
- Linen Included
- Lockers
- Luggage Storage
- Meeting Room
- No Curfew
- Non Smoking
- Reading Light
- Safety Deposit Box
- Taxes not included
- Tours/Travel Desk
- Towels For Hire
- Towels Included
Cancellation PolicyThis property has a 7 day cancellation policy. Failure to cancel within this time will result in a cancellation charge equal to the first night of your stay.
Must-Read Hostel InfoThis property has specific Terms & Conditions.
- Tourist tax ( amount KN 7,00 per person & day) NOT INCLUDED in price. This is obligation according rules by Croatian Ministry Tourism and will be charged additionally.
DirectionsShow MapHide Map
Walking directions to Jadranski trg 1, Rijeka, Croatia (Rijeka Port)
Riva Boduli
1. Head south on Riva Boduli toward Demetrova
450 m
2. Turn right onto Ignacija Henckea
61 m
3. Turn left onto Adamićeva
300 m
4. Turn right onto Jadranski trg
Destination will be on the right
16 m
Jadranski trg 1
Rijeka, Croatia


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Wednesday, April 6, 2011
More Clothing Burn Out
Instead, you get Cara - The Early Years.
Again, this is another picture where I can't place my age. There is a good chance that this is grade 6. Why my mother took this picture, I have no clue. However, I think it's hilarious: the baggy shirt tucked into the insanely high light wash jeans? Only topped by the acid wash backpack.
7 comments:
I love seeing older photos....you are cute as a little button in the first pic!!ReplyDelete
LOVE IT! Maybe this should be a FBFF project!ReplyDelete
Hahah, love the trip down memory lane. We have GOT to be the same age because I have lots of pictures that look like this!ReplyDelete
Awww you were a tiny fashionista! Soo cute. Between you and Hillary, I'm realizing I have like no of myself pictures earlier than like 2008. Maybe a spare one from 2005 or so but wow!ReplyDelete
What great photos- the first one is adorable and gotta love the baggy shirt and acid washed jeans- I rocked that look for a few years! Your comment made me laugh out loud- sorry you had to be introduced to me with my Canada butt hanging out!ReplyDelete
Oh the baggy t-shrit and jeans lookI pulled the look one to many times in my day. hahaha and I have to admit I like looking back as well and wondering why did my mom let me dress myself. Oh the good old days.ReplyDelete
Write it in Lipstick
i'm a follower and just a warning since I see your studying English at the Graduate level, my grammar is very poor. You've been warned.
I actually really like your red-headed outfit and look, ha ha! You're so cute as a kid - I especially love your classic early 90s (?) grade 6 look!ReplyDelete


text:
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Gen. Chester
(1922 - 2013)
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Brig. Gen. Chester J. Butcher
FORT MYERS, FL. - Chester John Butcher, 91, passed away November 15, 2013. He was born January 4, 1922 in Lafayette, Louisiana to the late Lawrence and Belle (Hotard) Butcher. In addition to his parents, he is preceded in death by his daughter, Judy; and brothers, Warren and Matt.
Brig. Gen. Chester J. Butcher was deputy commander of the Fifth Allied Tactical Air Force, Vicenza, Italy, which is a subordinate command of Allied Air Forces Southern Europe.
General Butcher was born at Lafayette, La., in 1922, where he graduated from Cathedral High School in 1938. He attended the University of Southwestern Louisiana for a year before entering the U.S. Military Academy, West Point, N.Y. While attending the academy he completed flight training, in 1942, and graduated in January 1943 with a bachelor of science degree and commission as second lieutenant. He also has a master of science degree in aeronautical engineering from
Princeton University
and a master of business administration degree from The George Washington University, and is a graduate of the Advanced Management Program, Harvard Business School.
World War II
, he was assigned to the 355th Fighter Group in England as flight commander and operations officer, and flew P-47 and P-51 aircraft. He was shot down in a P-51 while strafing German airfields in Southern France and spent a year and a half in German hospitals and prisoner-of-war camps. He was released in April 1945 and went to Shaw Field, S.C., as squadron commander.
In 1946 he attended the Command and General Staff School, Fort Leavenworth, Kan., and entered Princeton University for a year. He then was assigned as chief of the Fighter Test Section at the Air Proving Ground Center, Eglin Air Force Base, Fla.
General Butcher was assigned to Headquarters
U.S. Air Force
in January 1951 where he served as chief, Fighter Branch, Directorate of Research and Development. As an additional duty, he was a White House aide under the administrations of presidents Truman and Eisenhower. In September 1954 he was assigned to Air Defense Command headquarters at Ent Air Force Base, Colo., where he served as chief, Weapons Division, Plans and Requirements, Deputy Chief of Staff, Operations.
He returned to Headquarters U.S. Air Force in 1959 where he became executive officer to the assistant secretary of the Air Force for research and development and later was military assistant to the undersecretary of the Air Force. He attended the Industrial College of the Armed Forces for a year and then returned to be assigned successively as chief of the Air Defense, Strategic, and Space divisions, deputy chief of staff for research and development.
From December 1965 to April 1968, General Butcher was assigned as commander of the 3560th Pilot Training Wing, Webb Air Force Base, Texas. He again returned to Washington, D.C., where he served as deputy director for concepts and operational readiness, Defense Communications Planning Group in the Defense Communications Agency.
General Butcher assumed command of Task Force Alpha, Nakhon Phanom Royal Thai Air Force Base, Thailand, in June 1969. As commander, he was responsible for planning and directing the application of a wide variety of airpower resources in support of United States objectives in Southeast Asia.
In August 1970 he assumed duties as deputy commander of the Fifth Allied Tactical Air Force, a subordinate Command of Allied Air Forces Southern Europe.
His military decorations and awards include the Legion of Merit with two oak leaf clusters, Distinguished Flying Cross, Air Medal with nine oak leaf clusters, Meritorious Service Medal, Air Force Commendation Medal, Army Commendation Medal, and
Purple Heart
with oak leaf cluster. He is a command pilot.
He was promoted to the grade of brigadier general effective May 1, 1968, with date of rank April 30, 1968.
Upon retirement from the USAF in 1974, Chester and his family moved to Fort Myers, Florida. He was member of the Araba Shriners and the ROJ (Royal Order of Jesters). He loved to entertain friends and family, dance and golf. He was a member of the Cape Coral Country Club for many years.
Left to cherish his memory are his wife of 58 years, Harriett; son, Bruce and his wife Mary of Fort Myers, Florida; brothers, Tom and Daniel "Booney" Butcher; sister, Ruth Bowen all of Louisiana; granddaughters, Cathryn and Haydn Butcher.
There will be a Celebration of Life on Friday at 1:00 PM at Fort Myers Memorial Gardens Funeral Home, 1589 Colonial Blvd., Fort Myers, Florida 33907. Interment service with full military honors will follow in Fort Myers Memorial Gardens Cemetery.
Memorial contributions may be made in his honor to the Shriner's Hospital for Children at
or the Humane Society at
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1589 Colonial Boulevard
Fort Myers
(239) 936-0555
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ABI-007 in Treating Patients With Persistent or Recurrent Cervical Cancer
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This phase II trial is studying how well ABI-007 works in treating patients with persistent or recurrent cervical cancer. Drugs used in chemotherapy, such as ABI-007, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
Cervical Adenocarcinoma
Cervical Adenosquamous Carcinoma
Cervical Small Cell Carcinoma
Cervical Squamous Cell Carcinoma
Recurrent Cervical Carcinoma
Drug: Paclitaxel Albumin-Stabilized Nanoparticle Formulation
Other: Laboratory Biomarker Analysis
Phase 2
|Study Type:
|Study Design:
|Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|A Phase II Evaluation of ABI-007 in the Treatment of Persistent or Recurrent Squamous or Nonsquamous Cell Carcinoma of the Cervix
- Frequency and duration of objective response assessed by Response Evaluation Criteria in Solid Tumors (RECIST) [ Time Frame: Up to 5 years ] [ Designated as safety issue: No ]
- Frequency and severity of observed adverse effects assessed by Common Terminology Criteria for Adverse Events (CTCAE) [ Time Frame: Up to 5 years ] [ Designated as safety issue: Yes ]
- Survival time [ Time Frame: From study entry to death or date of last contact, up to 5 years ] [ Designated as safety issue: No ]
- Duration of progression-free interval [ Time Frame: From study entry until disease progression, death or date of last contact, up to 5 years ] [ Designated as safety issue: No ]
|Study Start Date:
|November 2006
|Primary Completion Date:
|February 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Treatment (paclitaxel albumin-stabilized nanoparticle)
Patients receive ABI-007 IV over 30 minutes on days 1, 8, and 15. Treatment repeats every 28 days in the absence of disease progression or unacceptable toxicity.
Drug: Paclitaxel Albumin-Stabilized Nanoparticle Formulation
Given IV
Other Names:Other: Laboratory Biomarker Analysis
Correlative studies
Detailed Description:
I. Estimate the antitumor activity of ABI-007 in patients with persistent or recurrent squamous or nonsquamous cell carcinoma of the cervix who have failed on higher-priority treatment protocols.
II. Determine the nature and degree of toxicity of ABI-007 in this cohort of patients.
III. To determine the expression of the SPARC (secreted protein, acidic and rich in cysteine) protein in the tumor tissue and plasma (exploratory study) of patients treated with this regimen.
OUTLINE: This is an open-label, multicenter study.
Patients receive ABI-007 IV over 30 minutes on days 1, 8, and 15. Treatment repeats every 28 days in the absence of disease progression or unacceptable toxicity.
Blood samples are collected at baseline and periodically during study for SPARC protein expression analysis by ELISA. Archived tumor tissue samples are also analyzed.
After completion of study treatment, patients are followed periodically for up to 5 years.
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Persistent or recurrent squamous or nonsquamous cell carcinoma of the cervix with documented disease progression
- Histologic confirmation of the original primary tumor
Measurable disease, defined as at least one target lesion that can be accurately measured in at least one dimension ≥ 20 mm when measured by conventional techniques, including palpation, plain x-ray, CT scan, or MRI, or ≥ 10 mm when measured by spiral CT scan
- Tumors within a previously irradiated field will be designated as nontarget lesions unless progression is documented or a biopsy is obtained to confirm persistence at least 90 days after completion of radiotherapy
Must have received 1 prior systemic chemotherapeutic regimen for management of advanced, metastatic, or recurrent squamous or nonsquamous cell carcinoma of the cervix
- Chemotherapy administered as a radiosensitizer is not a systemic chemotherapy regimen
- Not eligible for a higher priority GOG protocol
- GOG performance status 0, 1, or 2
- No active infection requiring antibiotics
- Platelet count ≥ 100,000/mm^3
- Absolute neutrophil count ≥ 1,500/mm^3
- Creatinine ≤ 1.5 times upper limit of normal (ULN)
- Bilirubin ≤ 1.5 times ULN
- SGOT and alkaline phosphatase ≤ 2.5 times ULN
- No neuropathy (sensory and motor) > grade 1
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must use effective contraception
- No evidence of any other invasive malignancies within the past 3-5 years, except localized breast cancer, head and neck cancer, cervical cancer, or nonmelanoma skin cancer
- No pre-existing hearing loss/tinnitus > grade 1
- No concurrent amifostine or other protective agents
- Recovered from effects of prior surgery, radiotherapy, or chemotherapy
Hormonal therapy directed at malignant tumor must be discontinued at least 1 week prior to study entry
- Continuation of hormone replacement therapy permitted
- At least 3 weeks since prior biological therapy and immunotherapy
No more than 1 prior cytotoxic chemotherapy regimen (either with single or combination cytotoxic drug therapy)
- May have received 1 additional noncytotoxic (biologic or cytostatic) regimen, including monoclonal antibodies, cytokines, or small-molecule inhibitors of signal transduction
No prior radiotherapy to any portion of the abdominal cavity or pelvis
- Radiotherapy for the treatment of cervical cancer within the past 5 years allowed
- Radiotherapy for localized breast cancer, head and neck or skin allowed provided completion > 3 years prior to study entry and remains free of recurrent or metastatic disease
No prior chemotherapy for any abdominal or pelvic tumor
- Chemotherapy for the treatment of cervical cancer within the past 5 years allowed
- Prior adjuvant chemotherapy for localized breast cancer provided completion > 3 years prior to study entry and remains free of recurrent or metastatic disease
- No prior therapy with ABI-007 or any other taxane
- No prior anticancer treatment that would preclude study therapy
- No concurrent ritonavir, saquinavir, indinavir, nelfinavir, or anticonvulsants
Please refer to this study by its ClinicalTrials.gov identifier: NCT00309959
Show 26 Study Locations
|Principal Investigator:
|David Alberts
|Gynecologic Oncology Group
No publications provided
|Responsible Party:
|Gynecologic Oncology Group
|ClinicalTrials.gov Identifier:
|NCT00309959 History of Changes
|Other Study ID Numbers:
|Study First Received:
|March 29, 2006
|Last Updated:
|December 29, 2014
|Health Authority:
|United States: Institutional Review Board
Additional relevant MeSH terms:
Carcinoma, Adenosquamous
Carcinoma, Small Cell
Carcinoma, Squamous Cell
Small Cell Lung Carcinoma
Bronchial Neoplasms
Carcinoma, Bronchogenic
Lung Diseases
Lung Neoplasms
Neoplasms by Histologic Type
Neoplasms by Site
Neoplasms, Complex and Mixed
Neoplasms, Glandular and Epithelial
Neoplasms, Squamous Cell
Respiratory Tract Diseases
Respiratory Tract Neoplasms
Thoracic Neoplasms
Antimitotic Agents
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Mitosis Modulators
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Therapeutic Uses
Tubulin Modulators
ClinicalTrials.gov processed this record on October 07, 2015


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Rollover image for closeup
Uilleann Brass Fitting for ConnectorItem #: MD.RP-UIL-FIT
List Price: $19.90
1 Review ) Write a Review >>>(
by Mid-East
Uilleann Pipe Accessory. Made by Mid-East. (MD.RP-UIL-FIT)
Free Shipping on this item in orders above $199
In Stock
Found in: Bagpipes
Uilleann Brass Fitting for Connector (RP-UIL-FIT) This is a brass fitting which has a connecting curved brass tube with hemp on the end. It attaches to the ebony Uillean Chanter Connector.
You connect the Chanter, with its reed in place, to the ebony Chanter stock. Slide the curved brass tube of the ebony Chanter stock into the small hole in the wooded chanter connector on the Bag's neck.
Stock on brass fitting has a 11/16 inch in diameter.


text:
Thursday, April 04, 2013
By Eric Brandner
Alison Simerly has gone through five deployments and two additional years of geographic separation, waiting for her father, Army Col. Mark Simerly, to come home. For military children like Alison, homecomings can be accompanied by aberrant emotions.
"I always felt this combination of heaviness and buoyancy," she said. "There's this initial outpouring of relief and joy and it's followed by all the issues that come from reintegration.
"He left a little girl and he came back to somebody who had developed a beauty routine and was driving," the 20-year-old said. "It's difficult to maintain communication when there's that growth that's occurred when he's been gone."
Children's deployment issues were at the heart of Wednesday's With You All the Way Symposium presented by The Comfort Crew for Military Kids. The event – held at the new USO Warrior and Family Center at Fort Belvoir, Va. – featured panel discussions on how homecoming, transition and resilience affect the lives of the youngest members of military families. It was part of the USO's activities to mark the Month of the Military Child.
Trevor Romain, the creative force behind The Comfort Crew and the USO-sponsored With You All the Way tours and support kits, said adults often tell children what they want to hear in attempts to fix problems rather than actually listening to their concerns.
"When children have come up to us after [presentations], really what they needed was validation of what they were going through, instead of somebody trying to fix it for them," he said. "There was a young boy recently who came up to us and just started crying. I said 'Are you OK?' And he said, 'I am now' and turned around and walked away.
"He needed that place to feel comfortable."
Dr. Lydia Marek, a research scientist in Virginia Tech's Department of Human Development, said studies indicate younger children – especially boys – have the most difficulty adjusting during deployment while older girls appear to have the most difficulty during post-deployment family reintegration.
"[Families] had to cope by changing things up, by rebalancing," she said. "There's the need for a lot of renegotiation of roles [when a service member returns]."
"We set up the homecoming like a Hallmark card," Romain said. "And it is always this … afterwards of emptiness."
Romain and the other panelists emphasized the power of transitional objects or buffers. In a series of interviews shown at the symposium, children from military families told Romain how they used activities as simple as driving bumper cars as a way to break the ice with a parent after deployment.
Army Lt. Col. Brian Zarchin, commander of the Fort Belvoir Headquarters Battalion, said he learned to ask for and heed his wife's advice about family changes when returning from an assignment.
"You're used to a different tempo when you're deployed and the family is on its own tempo … typically a little bit slower," he said.
Zarchin, who has spent three significant stints away from his family, said communication, understanding and unconditional love helped them weather the reintegration process. The transition wasn't without bumps. He told a story about returning from a yearlong deployment to find out his son Zack didn't remember their early time together.
"When we got back – he was 18 months old at the time – he was hiding behind Mom and he said, 'Who is him?'" Zarchin said. "Before that he was my best buddy."
While older, Simerly said it wasn't until she and her father found common ground between his deployments that they began to communicate more clearly.
"I think it's really easy to say 'just talk to each other.' But I think it takes a buffer … to be able to verbalize what you're both feeling," she said. "One of our biggest things was music. We went to shows together. We listened to new albums. We would just drive around in the car and listen to things that we both connected through. And to me, those lyrics said what we really couldn't verbalize."
* * *
Photo caption: Trevor Romain speaks as Alison Simerly looks on during Wednesday's With You All the Way Symposium at the USO Warrior and Family Center at Fort Belvoir, Va. (USO photo by Eric Brandner)
* Shop USO Wishbook to donate funds that helps more troops and families enjoy the programs and services that the USO offers worldwide.
USO P.O. Box 96860 Washington, DC 20077-7677 Phone: 1-888-484-3876
© 2015 USO, Inc. All Rights Reserved.


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Orioles Nation Blog
ON Mailbag 12/24 to 1/1
Welcome to this week's edition of the Orioles Nation Mailbag. Topics include the starting rotation, outfield options, and more. Please read and ask questions for the next edition of the ON Mailbag.
ON Mailbag 12/15 to 12/23
Welcome to this Week's ON Mailbag. Topics include options for the Orioles outfield. Please read and ask more questions for the next edition.
ON Mailbag 12/8 to 12/14
This week's ON Mailbag includes Orioles questions on the outfield for 2015. Please read and ask questions for next week's ON Mailbag
ON Mailbag 12/1 to 12/7
Welcome to this week's Orioles Nation Mailbag. Topics include Matt Kemp, Mike Morse, and other outfield options for the Baltimore Orioles.
Nick Markakis exits stage left; mistake by the Baltimore Orioles?
The Orioles failed to sign Nick Markakis. The Atlanta Braves signed Markakis to a four year deal. Was it a mistake for the Orioles to let Markakis walk?
Baltimore Orioles let Nelson Cruz walk, signs with Seattle Mariners
It has been reported by multiple outlets now that OF/DH Nelson Cruz has signed a four year deal for $57 million, including a $1 million signing bonus, with the Seattle Mariners. Also reported, the Baltimore Orioles were willing to go three years with Cruz and knew about the four year deal on the table, but […]
Baltimore Orioles spoke with Los Angeles Dodgers about Matt Kemp
After losing slugger Nelson Cruz to the Seattle Mariners in free agency, the Baltimore Orioles are turning their attention to the trade market to find another slugger for the middle of their lineup. Los Angeles Dodgers slugger Matt Kemp is at the top of the team's list.
ON Mailbag 11/26 to 11/30
This week's ON Mailbag includes topics on Bud Norris, Jonathan Schoop, and Matt Wieters. Please read and ask questions for the next edition of the ON Mailbag
The Baltimore Orioles have the pieces to acquire Jay Bruce
If the Baltimore Orioles want to replace the power the lineup will be losing when Nelson Cruz signs elsewhere, the Cincinnati Reds are interested in trading Jay Bruce for a few inexpensive, major league-ready players.
Ending the Baltimore Orioles major award drought in 2015
The Baltimore Orioles have been shut out of the awards race since 1991, which was when Cal Ripken won American League MVP. Grant Brisbee, from SB Nation, wrote an article highlighting when each team last won a major award. The Orioles have been shut out 66 straight times now. Who can end that streak in 2015?


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As I hear more about the concept of "crowdfunding" -- asking the public to help fund your idea in small increments of money -- I have found myself wandering onto websites like Kickstarter.com and Indiegogo.com that help connect willing donors with these ideas.
New stylus designed to help you write better on your device
It's fun to browse and to see what ideas are popular in various areas -- technology, music and movies, home items, toys, etc., which the sites broadcast in email digests or lists online.
A Kickstarter campaign for a stylus caught my attention a few months ago since I would love to use my iPad for handwritten notes and at the time had not yet found a stylus that worked as well as a pen on paper.
I loved the concept of this thin stylus, called the HAND Stylus, and noticed that its recently ended campaign had received more than $310,000 in funding (well above its $25,000 goal) from 7,511 backers, most who paid $30 for the idea and the promise of receiving a stylus if the project got off the ground.
My interest piqued when I received an emailed press release promoting this new stylus: Even though I missed the chance to contribute to the campaign, I felt like I had inside scoop, having watched the project go from idea to manufacturing to media campaign in just a few months.
"There would be no HAND Stylus without Kickstarter, and I feel like the rest of my life I'm going to be indebted to them," Alameda, Calif., designer Steve King said in a phone interview. King designed the stylus with a 4-mm tip, the smallest on the market, and founded the company behind it. "I'm still reeling a little bit that this thing happened and that it's real."
The stylus is the smallest on the market today, King said. Even though it doesn't quite mimic a ballpoint pen, it is as close as possible: Touchscreen technology doesn't yet allow a device like the iPad to read a conductive tip smaller than 4 mm.
Continue reading this story on the...


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Pavel Chekanov, 44, of 5 Cottage Lane, Millcreek Township, entered an open guilty plea to the charges, allowing sentencing Judge Samuel Kline to set the terms.
Harrisburg attorney Christopher Dreisbach, who represents Chekanov, said his client has served nine months in county prison since his arrest. Dreisbach said Chekanov had been sexually abused as a child.
Assistant District Attorney Megan Ryland-Tanner, who prosecuted the case, said the abuse involving two girls took place over eight years, starting in 2004. The older victim is now in college; the younger is 14.
Although most probation terms of two years or more are supervised by state probation officers, Ryland-Tanner said she preferred having Chekanov supervised by county probation. Ryland-Tanner said she spoke with Lebanon County Probation Director Sally Barry, who approved the unusually long five-year supervision for her department.
"I feel better with our local probation office doing the monitoring," Ryland-Tanner said.
Kline said state law makes it difficult for judges to keep sentences of two years or more local, but he agreed with Ryland-Tanner's recommendation.
Chekanov's younger brother, Michael, said family members had attempted to have Pavel enter treatment for his pornography addiction but failed.
"I knew him as a good person and a good brother," Michael said. "He managed to buy a house."
Michael, who lives in Philadelphia, said he was willing to give his older brother a room in his home and find him a job.
"I will trust him with my children," he said.
Before his arrest, Chekanov had a good job, working as an electrician for Henry Molded Products, Dreisbach said. Douglass Henry, the firm's owner, has continued to visit Chekanov while he has been in prison.
When Kline asked Chekanov if he had any comment, Chekanov was unable to speak initially, sobbing heavily.
After composing himself, Chekanov said he left Ukraine in 1997 but had grown addicted to pornography during a 15-year period.
"I tried to live honestly," he said. "I'm very sorry for what happened. ... I'm taking full responsibility."
While in prison, Chekanov said, he has tried "to fill my mind with nothing but the Bible and listening to a Christian radio station."
I worship God and try to stay in a close relationship with my spiritual family," he said.
Chekanov is trying to "restore a broken relationship with my wife."
Kline noted that Chekanov had no prior criminal record, and his most serious charge allowed for a minimum sentence of three to 12 months of incarceration.
"The goal is to prevent Pavel from having any contact with the victims as long as possible," the judge said. "These young ladies are under an incredibly difficult position."
Speaking to Chekanov, Kline said, "You are starting to realize what you did over a long period of time has devastated your immediate family and your extended family."
Kline fined Chekanov $850 and ordered him to have no contact with either victim.
firstname.lastname@example.com; 717-272-5611, ext. 152


text:
The Blog
The Daily Grind
10:37 AM, Apr 19, 2010 • By MARY KATHARINE HAM
In defense of the Americanization of the British election.
Gregg: "It's really disingenuous for some people to pursue regulatory reform based off this one instance," he said on MSNBC. "This is a single event, we don't even know what the outcome will be."
"Mostly white" newspapers smear "mostly white" Tea Parties.
A Washington Post columnist comes to the Tea Party: "Nevertheless, on the whole, they struck me as passionate conservatives dedicated to working within the system rather than dangerous militia types or a revival of the Ku Klux Klan."
Robert Samuelson: "The implicit, though often unstated, message is that a VAT could raise so much money it could eliminate future deficits by itself. This reasoning, if embraced, would create staggering tax burdens and exempt us from a debate we desperately need."
Wall Street questions the timing.
Recent Blog Posts
The Weekly Standard Archives
Browse 19 Years of the Weekly Standard


text:
Natura Bissé
Diamond White Rich Luxury Cleanse, 200ml
Editors' Notes
Achieve and preserve a pristine complexion with Natura Bissé's enriching gel cleanser. Fortified with a Brightening Acid Complex, this face wash removes every type of impurity while it softens and illuminates your skin.
- Free from parabens
- Removes makeup, evens tone and prevents dehydration
- Brightening Acid Complex to energize and promote flawless skin
Instructions for use:
- Use daily morning and/or night on the face, neck and décolletage
- Utilize the spatula to apply on the palm of your hand, gently massaging on the targeted areas
- Moisten the areas to create a rich emulsion, cleansing it off with a warm damp sponge
- For best results, follow with Diamond White Clarity toning lotion
- 200ml/7 fl.oz.
Product code: 355965 - Need help? Contact us