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A Universe from Nothing: Why There Is Something Rather Than Nothingby Lawrence M. Krauss and Richard Dawkins
Staff Pick
Lawrence Krauss's new book, A Universe from Nothing: Why There Is Something Rather Than Nothing, summarizes the continuing developments in the field of cosmology. In addition to championing these new insights in the study of modern physics, Krauss also frames these advances in the appropriate context of their resulting implications for theologians and deists. Adapted from a lecture he delivered at the 2009 Atheist Alliance international annual convention (and made popular on YouTube), A Universe from Nothing explores the history of the universe from the big bang through inflation to its theoretical endpoint using the most current (and widely accepted) science.
Krauss is marvelously adept at conveying his broad scientific knowledge in as succinct and lucid a manner as is perhaps possible, making it relatively easy for a nontheoretical physicist to grasp the concepts he is attempting to illustrate. Among the more notable and recent advancements that Krauss examines in the book are the discoveries that the universe is now accelerating following the so-called "cosmic jerk" that took place some five billion years ago (see also the 2011 Nobel Prize in Physics), the abundance of dark energy that appears to account for nearly three-quarters of the universe's total mass (that resides mostly in "empty space"), and the uniform flatness that characterizes our universe. The majority of the book is spent assembling and explaining the related pieces that together form a picture of the universe which, according to the latest scientific data, seems to have evolved from nothing — in fact, it may have only been able to evolve precisely because there was nothing.
The ultimate arbiter of truth is experiment, not the comfort one derives from one's a priori beliefs, not the beauty and elegance one ascribes to one's theoretical models. The results of experiments that I will describe here are not only timely, they are also unexpected. The tapestry that science weaves in describing the evolution of our universe is far richer and far more fascinating than any revelatory images or imaginative stories that humans have concocted.
As our understanding of the nearly 14-billion-year-old universe is constantly evolving, there is clearly much to be learned about cosmology. Krauss is enthusiastic in his dissemination of the accumulated knowledge and seems eager to welcome whatever conceptual refinements future advancements will inevitably bring. A Universe from Nothing is not simply a scientific treatise, however, as Krauss considers what ramifications these new insights have on age-old theological arguments.
For more than two thousand years, the question, "Why is there something rather than nothing?" has been presented as a challenge to the proposition that our universe — which contains the vast complex of stars, galaxies, humans, and who knows what else — might have arisen without design, intent, or purpose. While this is usually framed as a philosophical or religious question, it is first and foremost a question about the natural world, and so the appropriate place to try and resolve it, first and foremost, is with science.
Richard Dawkins, in the book's afterword, characterizes Krauss's book as "the knockout blow" to the theologian's remaining arguments in favor of a creator. With a few hundred billion galaxies in the observable universe and a modern physics that seems to indicate that our universe could have only arose from nothing, Krauss's assertion that a god is "unnecessary — or at best redundant" is as compelling as the science he uses to arrive at said claim. A Universe from Nothing, like most books of reason and evidence, will do little to dissuade those who ardently profess their belief in a deity, but as cosmology clarifies our place in the universe with greater precision, the arguments in favor of a creator seem ever less defensible. Krauss, in this eminently readable (and often funny!) book, has ventured further down the road of rationality and empiricism, allowing us a guided tour on the never-ending quest to truly understand the nature of life in this brilliant universe we call home.
If we wish to draw philosophical conclusions about our own existence, our significance, and the significance of the universe itself, our conclusions should be based on empirical knowledge. A truly open mind means forcing our imaginations to conform to the evidence of reality and not vice versa, whether or not we like the implications.
Recommended by Jeremy, Powells.com
Synopses & Reviews
Publisher Comments:
The astounding New York Times bestseller — updated with an explanation of the Higgs Boson and its implications for our understanding of empty space — that offers new answers to the most basic philosophical questions: Where did the universe come from and what is the meaning of its origins for our lives today?
What came before the universe? Why is there something rather than nothing? These questions have been at the center of religious and philosophical debates about the existence of God, even though they are essentially scientific questions about how the universe actually functions.
With wry humor and wonderfully clear explanations, Krauss takes us back to the beginning of the beginning, presenting the most recent evidence for how our universe evolved — and how it's likely to end. This knowledge that our universe will be quite different in the future has profound implications and directly affects how we live — or should live — in the present.
A Universe from Nothing is a provocative, game-changing entry into the debate about the existence of God and why everything exists.
"In A Universe from Nothing, Lawrence Krauss has written a thrilling introduction to the current state of cosmology — the branch of science that tells us about the deep past and deeper future of everything. As it turns out, everything has a lot to do with nothing — and nothing to do with God. This is a brilliant and disarming book." Sam Harris, author of The Moral Landscape
"Astronomers at the beginning of the twentieth century were wondering whether there was anything beyond our Milky Way Galaxy. As Lawrence Krauss lucidly explains, astronomers living two trillion years from now, will perhaps be pondering precisely the same question! Beautifully navigating through deep intellectual waters, Krauss presents the most recent ideas on the nature of our cosmos, and of our place within it. A fascinating read." Mario Livio, author of Is God A Mathematician? and The Golden Ratio
"In this clear and crisply written book, Lawrence Krauss outlines the compelling evidence that our complex cosmos has evolved from a hot, dense state and how this progress has emboldened theorists to develop fascinating speculations about how things really began." Martin Rees, author of Our Final Hour
"A series of brilliant insights and astonishing discoveries have rocked the Universe in recent years, and Lawrence Krauss has been in the thick of it. With his characteristic verve, and using many clever devices, he's made that remarkable story remarkably accessible. The climax is a bold scientific answer to the great question of existence: Why is there something rather than nothing." Frank Wilczek, Nobel Laureate and Herman Feshbach professor at MIT, author of The Lightness of Being
"With characteristic wit, eloquence and clarity Lawrence Krauss gives a wonderfully illuminating account of how science deals with one of the biggest questions of all: how the universe's existence could arise from nothing. It is a question that philosophy and theology get themselves into muddle over, but that science can offer real answers to, as Krauss's lucid explanation shows. Here is the triumph of physics over metaphysics, reason and enquiry over obfuscation and myth, made plain for all to see: Krauss gives us a treat as well as an education in fascinating style." A. C. Grayling, author of The Good Book
"We have been living through a revolution in cosmology as wondrous as that initiated by Copernicus. Here is the essential, engrossing and brilliant guide." Ian McEwan
"Nothing is not nothing. Nothing is something. That's how a cosmos can be spawned from the void — a profound idea conveyed in A Universe From Nothing that unsettles some yet enlightens others. Meanwhile, it's just another day on the job for physicist Lawrence Krauss." Neil deGrasse Tyson, Astrophysicist, American Museum of Natural History
One of the few prominent scientists today to have crossed the chasm between science and popular culture, Krauss describes the staggeringly beautiful experimental observations and mind-bending new theories that demonstrate not only can something arise from nothing, something will always arise from nothing. With a new preface about the significance of the discovery of the Higgs particle, A Universe from Nothing uses Krauss's characteristic wry humor and wonderfully clear explanations to take us back to the beginning of the beginning, presenting the most recent evidence for how our universe evolved — and the implications for how its going to end.
Provocative, challenging, and delightfully readable, this is a game-changing look at the most basic underpinning of existence and a powerful antidote to outmoded philosophical, religious, and scientific thinking.
One of the few prominent scientists today to have crossed the chasm between science and popular culture, Krauss describes the staggeringly beautiful experimental observations and mind-bending new theories that demonstrate not only can something arise from nothing, something will always arise from nothing. With a new preface about the significance of the discovery of the Higgs particle, A Universe from Nothing uses Krausss characteristic wry humor and wonderfully clear explanations to take us back to the beginning of the beginning, presenting the most recent evidence for how our universe evolved—and the implications for how its going to end.
Provocative, challenging, and delightfully readable, this is a game-changing look at the most basic underpinning of existence and a powerful antidote to outmoded philosophical, religious, and scientific thinking.
About the Author
Lawrence M. Krauss is director of the Origins Project at Arizona State University. He is the author of more than 300 scientific publications and nine books, including the bestselling The Physics of Star Trek, and the recipient of numerous international awards for his research and writing. Hailed by Scientific American as a "rare scientific public intellectual," he is also a regular columnist for newspapers and magazines and appears frequently on radio and television.
Richard Dawkins is a Fellow of the Royal Society and was the inaugural holder of the Charles Simonyi Chair of Public Understanding of Science at Oxford University. He is the acclaimed author of many books including The Selfish Gene, Climbing Mount Improbable, Unweaving the Rainbow, The Ancestor's Tale, The God Delusion, and The Greatest Show on Earth. Visit him at RichardDawkins.net.
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By OGJ editors
HOUSTON, Nov. 17 -- A recapitalized PostRock Energy Corp., Oklahoma City, plans to convert to more customized frac treatments on its Southeast Kansas coalbed methane properties.
The company is also attempting to sell most of its Marcellus shale assets in West Virginia. It plans to disclose its 2011 drilling program in January.
Production is steady at 54 MMcfd of gas equivalent. The company drilled and completed 27 wells and returned 42 to production in the Cherokee basin in the quarter ended Sept. 30, bringing year-to-date totals to 141 and 232, respectively.
A fair number of wells completed in this year's first two quarters didn't achieve peak production rate as expected. Detailed engineering studies of the underperformance indicate that the "historical approach to zonal fracture treatments is too standardized, and not as transferrable across the basin as we once believed," PostRock said last week.
"On future development projects, custom fracture treatments tailored to zone and region will be employed to maximize the effectiveness of each completion stage," the company said.
PostRock owns and operates more than 2,800 wells and nearly 2,200 miles of gas gathering lines in the basin in Kansas and Oklahoma (OGJ, Nov. 1, 2010, p. 62). It also owns a 1,100 miles of interstate gas pipelines serving parts of Oklahoma, Kansas, and Missouri.


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'Monsta Lobsta' gets perfect inspection
Published On: Oct 19 2012 07:06:12 PM EDT Updated On: Oct 19 2012 07:10:00 PM EDT
Local 6's Matt Austin goes behind the kitchen door of a seafood food truck that has received perfect inspections
Copyright 2012 by ClickOrlando.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Saturday Night Salsa Lessons and Salsa Dancing.
$10 Cover charge (Does NOT include Salsa Lesson)
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Salsa dancing from 10:00pm until 1:45 am featuring the hottest bands in southern California
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Upcoming Events: Jan 26th: Chino Espinoza y Los Duenos del Son Feb 2nd: Fermin y su Salsa Fusion Feb 9th: Conjunto Oye (11 piece band) Feb 16th: La Charanga Cubana Feb 23rd: Orquesta Guayao
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Best Spanish Restaurant That Doubles as a Nightclub Orange County 2014


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Elijah Soria of Santa Clara waits for the train ride to start at the Day Out with Thomas event on Sunday in Fillmore.
Two boys hang out of the window of a passenger car pulled by Thomas the Tank Engine as they return to the station Sunday in Fillmore.
Terri Gennaro (from left); her husband, Mike; and their daughter, Kelly; with her son, Dominic, of Simi Valley, have their photo taken Sunday in Fillmore.
Min Tran of El Segundo helps his son, Pax, as he plays with trains at the Day Out with Thomas on Sunday in Fillmore.
People have their photo taken with Thomas the Tank Engine during the Day Out with Thomas on Sunday in Fillmore.


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|Issue 15.03 - March 2007
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View to a Kill
PROBLEM A great white shark attack lasts just a second. It's only after the strike - when there's an explosion of water and animal parts - that the human eye registers the hit. Slowing the action is the one way to pull apart the flood of fins, water, and teeth, but watching animals attack in slo-mo has been done for years. How do you make Jaws look fresh?
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- Reader rants and raves.
- More »
- ASTRONOMY Stargazing with sidewalk Galileos.
- VIRTUAL WORLDS Puffle kerfuffle at Club Penguin.
- STARTUPS Launch party 2.0.
- More »
SOLUTION To turn a seal massacre into a visual spectacle, the BBC used a Photron high-speed camera, which captures 1,000 frames per second (the next-best shooter snags 500 fps). The Photron is typically reserved for highly controlled settings - ballistics labs and collision test sites - where the same basic action is filmed over and over. To ready the gadget for the high seas, the crew jury-rigged a Record button and turned a bike wheel into a stabilizer. In the end, this stretched a split second attack into a 40-second sequence.
Roll over the labels to see more...
Typically, a crew will get just a couple of complete attacks in a monthlong shoot; this group caught 10. Footage of three strikes made the final cut.
Footage filmed from a boat can look jumpy. But producers didn't want to drop $1,000 a day on a pricey camera stabilizer. So they made their own by ripping the spokes out of a bicycle wheel and lashing it to the deck. A cameraperson stood inside it, with the wheel encircling his waist. A wide stance kept him stable, and he was able to lean against the rim for support.
When the great white breached, the six-member team was roughly 50 feet away on a 20-foot motorboat. Any closer and the 2-ton behemoth could have ended up on deck.
The crew sailed along the coast of South Africa to a favorite cape fur seal hangout. Great white sharks regularly visit the spot for dinner, often charging the mammals from just below the surface of the water.
The Photron is usually controlled not by the shooter but by a cameraperson stationed at a laptop. But scanning for seals while operating the PC is difficult to do, and the laptop operator could easily miss the shot. So crew members rigged up a trigger button using a doorbell. They wired it to the camera so the shooter could start filming the moment a pup appeared. Leaving the Photron on constantly isn't an option - it drains power and eats memory.


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Ellie Goulding & McCabe Watch A High Speed Chase
September 10, 2012 6:57 PM
Ellie Goulding stopped by to chat with McCabe. Things took a turn when a high speed chase in Arleta caught Ellie and McCabe's attention. She was so into it, she almost missed her flight to San Francisco.
When asked about high speed chases in England Ellie said, "yeah, we don't have anything like this. It's starting to annoy me. I'm just like, please just stop."
Not all was lost though. Now we know about her upcoming show at The Troubadour on October 16th.
-AJ Gordon, AMP Radio


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Caroline Cooper appears in the following:
James Levine Scales Down Remainder of Season at the Met
Monday, March 21, 2011
In yet another indication of James Levine's troubled health, the Metropolitan Opera music director today announced his reduced schedule for the remainder of the season.
A Millionth Subscriber for Spotify, a Million Miles from Napster
Tuesday, March 08, 2011
The online music service Spotify, which boasts a considerable classical music catalog, has surpassed its one-million subscriber mark. Considered a European answer to iTunes, it has been trying to enter the American market.
Watch that Sword! Carmen Goes 3D
Monday, March 07, 2011
In the latest effort to bring a populist touch to opera, London's Royal Opera House has teamed up with a developer of 3D movie technology to offer a new 3D film version of Carmen. It's screening in several New York area theaters this week.
Detroit Symphony Musicians Offer to Return with No Contract
Tuesday, March 01, 2011
Striking musicians with the Detroit Symphony Orchestra say they'll return to work without a contract. Cellist and spokesman Haden McKay says the issues will be worked out through binding arbitration, after a contentious, nearly five-month strike.
Detroit Symphony Orchestra's Full Percussion Section Quits
Tuesday, March 01, 2011
In the latest twist in the Detroit Symphony Orchestra strike, the full percussion section has announced their departure. The news comes in the wake of the cancellation of the remainder of the orchestra's season.
In Oregon, the Sweet Sounds of Crime Reduction
Monday, February 28, 2011
Classical music soothes the savage breast -- at least that's the hope of law enforcement officials in Portland, OR. A new bill now in committee seeks to install classical music speakers in some of the city's most troubled transportation hubs.
Protest Greets Performance of Israel Philharmonic Orchestra at Carnegie
Wednesday, February 23, 2011
Pro-Palestinian protesters clogged the sidewalks surrounding Carnegie Hall Tuesday night as the Israel Philharmonic Orchestra performed its third concert on a current eight-concert tour of the United States.
Not Turning Back: DSO Joins List of American Orchestra Walk-Outs
Tuesday, February 22, 2011
With the Detroit Symphony musicians's rejection of its management's latest contract offer on Saturday, the beleaguered company has ground to a near complete halt. Yet it's just the latest example of contentious, grinding negotiations in the orchestra world.
Met Opera Announces Good Health, New Season
Wednesday, February 16, 2011
The Metropolitan Opera announced its 2011-12 season on Wednesday. Amid plans for the second two installments of Robert Lepage's Ring cycle and a World War II-era Faust, the big news to emerge was from the podium.
Racked by Visions, Chopin May Have Suffered from Epilepsy
Monday, February 14, 2011
Frédéric Chopin suffered from a variety of health problems, but one may have been overlooked until now: Temporal-lobe epilepsy. Recently published research offers a new development in the ongoing quest to diagnose the Polish composer.
From the Vaults: George Jellinek in Conversation with Grace Bumbry
Tuesday, February 08, 2011
Throughout February, we're honoring Black History Month with selections from the WQXR archives that recognize African American artists. In this 2002 interview, the late host George Jellinek sits down with star mezzo Grace Bumbry.
From the Vaults: George Jellinek Pays Tribute to Leontyne Price
Tuesday, February 08, 2011
In honor of Black History Month, we're featuring selections from the WQXR archive with great African American artists. Here the late host George Jellinek reaches into his own vaults for a 1996 RCA Victor-produced interview with Leontyne Price.
New York Pops to American Airlines: Prepare for Takeoff
Monday, February 07, 2011
The New York Pops and American Airlines announced a new deal that will have the country's largest independent pops orchestra streaming on American's inflight channels.
Veteran Conductor Riccardo Muti to Undergo Surgery After Fall
Monday, February 07, 2011
Chicago Symphony Orchestra music director Riccardo Muti sustained "multiple facial and jaw fractures" last week in a fall from the podium. "It's a wait and see situation," said an orchestra spokeswoman.
Cairo Opera House Shuts Its Doors after Unrest
Monday, January 31, 2011
The lights have gone down at the Cairo Opera House, one of the African continent's most celebrated venues for classical and contemporary music, as unrest in Egypt continues.
A Powerhouse Pianist Shakes Up the State Dinner
Tuesday, January 25, 2011
As diplomats and luminaries gathered last week to honor Chinese president Hu Jintao, they were treated to a performance by Lang Lang -- and a front row seat to perhaps the White House's first classical music controversy.
Nixon in China: An Insider's Perspective
Monday, January 24, 2011
U.S. diplomat Winston Lord had a nearly four-decade long relationship with China, including a front-row seat to the historic 1972 meeting between Nixon and Mao, the subject of John Adams' opera Nixon in China. The opera has its Met premiere on Wednesday.
Acoustics a Driving Force in New Gehry-Designed Hall
Wednesday, January 19, 2011
This week, Miami's New World Symphony unveils its just-completed concert hall, the work of famed architect Frank Gehry. But the facility's acoustic design, as much as its physical one, will be the focus of concertgoers.
That Was Then: Zeffirelli on La Traviata
Friday, January 14, 2011
The Met's new La Traviata signals the retirement of a 1998 production by director Franco Zeffirelli. In this 1983 WQXR broadcast, Zeffirelli discusses his film version of La Traviata, the rich grandeur of opera and the wisdom of "certain liberties."
Love that Symphony? Your Brain Does Too
Monday, January 10, 2011
Can't get enough of Chopin or Brahms? New research suggests the music you love doesn't just sound good, it can actually provoke natural chemical reactions in the brain associated with pleasure and positive feeling.


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Toronto Raptors v Philadelphia 76ers
Nick Young of the Philadelphia 76ers celebrates during the game... NachrichtenfotoBasketball,Feiern,Horizontal,Nick Young - Basketballspieler,Philadelphia - Pennsylvania,Philadelphia 76ers,Profi-Basketball in der NBA,Sport,Sportbegegnung,Toronto Raptors - Basketballmannschaft,USA,Wells Fargo Center - PhiladelphiaPhotographer Jesse D. GarrabrantCollection: National Basketball Association 2012 NBAEPHILADELPHIA, PA - NOVEMBER 20: Nick Young #1 of the Philadelphia 76ers celebrates during the game against the Toronto Raptors at the Wells Fargo Center on November 20, 2012 in Philadelphia, Pennsylvania. NOTE TO USER: User expressly acknowledges and agrees that, by downloading and or using this photograph, User is consenting to the terms and conditions of the Getty Images License Agreement. Mandatory Copyright Notice: Copyright 2012 NBAE (Photo by Jesse D. Garrabrant/NBAE via Getty Images)


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Bath's Bell Inn Saved By Community Buyout Scheme
A poster advertising the Bell share offer is displayed outside the... News PhotoAdvertisement,Bell,England,Horizontal,Human Interest,Poster,UKPhotographer Matt CardyCollection: Getty Images News 2013 Getty ImagesBATH, ENGLAND - MARCH 21: A poster advertising the Bell share offer is displayed outside the Bell Inn in Walcot Street on March 21, 2013 in Bath, England. Customers of the popular music venue have raised 720000 GBP to buy the pub from its current owner in a campaign to save it, which has been backed by rock stars including Robert Plant and Peter Gabriel. When the pub was put up for sale, customers launched a buyout with shares priced from 500 GBP to 20,000 GBP to initially raise 500,000 GBP with a loan to cover the shortfall in the asking price of 925,000 GBP. (Photo by Matt Cardy/Getty Images)


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Chateau Chauvin (1.5 Liter Magnum) 2005
Bordeaux Red Blends from St-Emilion, Bordeaux, France
Winemaker's Notes
The grapes are picked at the optimal ripeness level: harvesting is carried out by hand and the grapes are placed in trays to be transported back to the winery. At Chauvin, the wine is made in the traditional way, while also making the most of what modernity has to offer: nothing is done systematically and each year every effort is focused on adapting the techniques used to the qualities of that year's grapes.
Critical Acclaim
The Wine Advocate - "Chauvin's successful 2005 ranks alongside their 2000 and 1998. Its dense ruby/purple color is followed by lovely aromas of black currants, cherries, smoke, meats, and minerals. Superb purity, full body, good acidity, and moderate tannin suggest this fleshy, substantial St.-Emilion will be drinkable in 3-4 years, and last for 15 or more. Rating 90-92 Points."
Chateau Chauvin Winery
The vineyard is located to the north-east of Saint-Emilion, near Pomorol, half-way between Cheval-Blanc and La Cote Roi. The 37 acres are planted with 75% Merlot, 20% Cabernent Franc and 5% Cabernet Sauvignon. The soil of the estate is sandy while the subsoil is characterised by the presence of clay and iron.
We have been in partnership with BIOVITIS since 1994. Half of the vineyard is ploughed mechanically, while the other half is cultivated with grass-cover between the rows. Green harvesting is carried out throughout the vegetation cycle, to bring yields to 35 to 40 Hl/Ha.
At Chauvin the wine is made in the traditional way, while also making the most of what modernity has to offer: nothing is done systematically and each year every effort is focused on adapting the techniques to the qualities of that year's grapes. View all Chateau Chauvin Wines
About St-Emilion(saint eh-meel-YOHN)
A region named after the charming, quaint historical town in Bordeaux, St-Émilion is situated on the right bank of Bordeaux. It's grapes of choice are Merlot and Cabernet Franc (called Bouchet on the right bank). The region has its own classification system, updated and revised every few years. Two of the hottest chateaux of the area (and the only Premier Grand Cru Classé A) are Chateau Ausone and Chateau Cheval Blanc.
Notable Facts
St.-Émilion produces the most wine on the right bank of Bordeaux. As most of its wine is based primarily on Merlot, St-Emilion wines are described as having finesse and elegance. The best wine of the region can last upward of 10-20 years, like a good left-banker, but many find that the wines here matuer earlier than those based on Cabernet Sauvignon. The soils in the area differ greatly, from gravel to limestone to clay and sand. As a result, the wines of this region are diverse. Quality wines display silky tannins and ripe, soft fruit – the higher quality wine showing full-bodied texture and layers of complexity.
About France - Other regionsWhen it comes to wine, France is a classic. Classic blends, grapes and styles began in the country and they still remain. Think about it - people ask for a Burgundian style Pinot Noir, they refer to wines as Bordeaux or Rhone blends - Champagne even had to pass a law to stop international wineries from putting their region on the label of all sparkling wine.
The top regions of France are: Bordeaux, Burgundy, Champagne, Languedoc-Roussillon, Loire, Rhone. And these regions are so diverse! It makes sense that wine regions throughout the world try to emulate their style. Pinot Noir, Chardonnay, Cabernet Sauvignon and Syrah are no longer French varieties, but international varieties. They may not be the leader of cutting edge technology or value-priced wines, but there is no doubt that they are still producing wines of great quality and diversity.
Customer ReviewsSign In to Add Your Review0 }div>
Alcohol By Volume GuideMost wine ranges from 10-16% alcohol by volume. Some varietals tend to have higher (for example Zinfandel and Cabernet Sauvignon) or lower alcohol levels (Pinot Noir and many white varietals), but there is always some variation from producer to producer. Some wine falls outside of this range, for instance Port weighs in closer to 20%, while Muscat and Riesling are usually a bit below 10%.
Wine Style Guide
Light & Fruity
- Red wines that are more fruit-forward and lighter in tannin and body.
Smooth & Supple
- Medium bodied reds that go down easy, with smooth tannins and supple fruit.
Earthy & Spicy
- Wines where earthy and/or spicy dominate the flavors – typically medium to full body.
Big & Bold
- Full bodied wines that have concentrated fruit and are higher in alcohol and/or tannins. Some need age.


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I am wondering if I am missing anything by not having a quilt? I am a side sleeper and have tried out a few of the wider quilts but really don't see the gain. I guess for me I like the 6 oz weight that allows me to zip it up and pull over the hood if I need it or unzip it all the way and splay it out like a quilt. Is that really the difference? Am I as a side sleeper missing something?
youre a side sleeper using a quilt, the only thing missing is a hammock. even though i strictly use quilts i dont see how they are effecient on the ground. it makes far more sense to use a quilt in a hammock just as it makes sense that a sleeping bag doesnt work well in one. on the ground, id rather use a bag so i dont have to fiddle with flaps and drafts and uncomfort! these are distractions, and i need none of that while catching ZZzz's
Edited by mikeinfhaz on 10/30/2008 08:58:45 MDT.
As you note, many sleeping bags can be used like a quilt so there is little functional advantage of a quilt. 5 years ago there was a significant weight advantage with quilts. These days the weight advantage has eroded a fair bit. I am happy using my quilt, but if I was purchasing something today I don't honestly know if I would go for a quilt or a bag.
Edited by verber on 10/30/2008 09:11:09 MDT.
Brett:I've used a quilt for years (in all seasons except the dead of winter), and I'm a multi-positional sleeper. I do know that some people, as Michael points out, are uncomfortable with the "fiddle" factor'—but I find that quilts offer far more options for comfort than sleeping bags—and at night I seem to make the adjustments without even thinking about them (or even waking up). Perhaps after a while the process becomes conditioned second nature—like driving a car with a standard transmission. On the other hand, however, one of my hiking friends tried real hard but never was able to adapt himself to the quilt—and has sold both of his quilts and gone back to sleeping bags. If you've tried using a quilt and aren't sleeping well, then switch to something that works better for you Even if the weight differential between bags and quilts were greater than it is today—a badly spent night can degrade the best parts of the next day.Michael:I have considered a hammock, but nowadays my wife and I travel the backcountry together and share our bedding—if there are any two-person hammock systems I've not come across one (and admittedly never even thought to look until just now).LIBERTAS+PAX PACIS
youll have to visit the hammock forums online (same folk operate WB) for those answers. I do know that it is possible to hang 2 hammocks from 3 trees, while sharing the same tarp. But, I think the quickest way to a divorce is sharing the same hammock, second quickest way is paddling the same canoe. :)I understand the benefits of each sleeping system, so I ask this: why not have both?
Edited by mikeinfhaz on 10/30/2008 10:47:32 MDT.
I made a very lightweight (summer only) doulbe quilt with one layer of 2.6 oz climashield because I feel that down at that small thickness is too difficult to manage. Otherwise, I use my Western Mountaineering, full zip bags as quilts if I get overheated in "bag mode."As a side note: I do paddle with my wife. Here is the secret to success: give her a paddle but tell her, "Don't get this wet, Honey." :-)
It should not be forgotten that native northern populations, e.g., the Eskimos and the Lapps, have developed clothing systems comparable to what modern technology and materials can produce, but never "invented" a sleeping bag; they used furs or blankets. The sleeping bag was invented by the early polar explorers to serve a special need; optimal thermal protection with a minimum of weight. This is still the main objective of all military sleeping systems. What is the main objective of UL backpacker's quilt sleeping systems?
Edited by richard295 on 10/30/2008 11:08:00 MDT.
Flexibility and weight reduction.
One way of meeting a "main objective":By sharing one two-person sized sleeping quilt system my wife and I can sleep comfortably at temperatures about 10 or more degrees Fahrenheit lower than we could with the same insulation in two separate quilts, but then, we also get along well in canoes, 2-person kayaks, and for six straight days of cold October drizzle punctuated by heavy rain in the NH White Mountains (our honeymoon a decade ago) —lightweight egos and psychological flexibility seem to help.Michael S: I did a quick check on two-person hammocks on WB, thanks. Applying the concept in the wild seems impractical to me, but who knows, a couple of decades ago so did UL backpacking to most people.
Edited by lrmblue on 10/30/2008 14:37:14 MDT.
"Michael S: I did a quick check on two-person hammocks on WB, thanks."I was offering you to visit the Hammockforums.net without re-directing the discussion. Sorry for being vague. Those guys over there walk the walk about hammocks and systems (well it is a hammock forum after all :)OP: i think if you side sleep on the ground you wont gain much by using a quilt over a full zip bag. What I mean is that by the time you use a quilt large enough to cover your body without un-tucking itself, the weight savings just isnt there. Just my 2 cents. You could however, totally contradict my opinion with fact by using something like the JacksR Better "no sniveller" and find that it works much better than your current bag. Like I say, use both. Nothing (at least i havent found it) works for all conditions.
Edited by dstenberg1 on 10/31/2008 09:21:00 MDT.
I made the switch to a quilt this year and i wished i had done it years ago. I am a side and stomach sleeper and hated being confined in a sleeping bag. Now i can toss and turn to my hearts content!:)The quilt (Nunatak Arc Specialist) is wide enough so that drafts aren't a problem. I'm trying to take it as low as i can go this winter using down clothing. If i get too cold, then i will order a warmer quilt. I can't see myself going back to a 'normal' sleeping bag.Quilts are quite a bit lower in weight, but the main issue for me, is that i now sleep better with the freedom to move under my quilt.:)
In a sense, a quilt, when it's closed tight beneath one, is like a bag which has only one vertical baffle, centered on the underside. I'm not sure how this works in practice, but it seems like the down under body weight, and movement, can squirt sideways, self-optimizing and avoiding compression. I do know that I sleep warmer in a quilt per ounce of carried weight than I do in a bag, and that the quilt seems to collapse around me better, leaving less air volume to heat, than with a bag.One thing to think about is that bag companies have to design products that look good in a store--plump, with a pleasing shape. I think this moves the design of most bags in the direction of being a semi-rigid bottle, which makes it hard to get the bag as close to ones body as possible and eliminate intervening air. A good quilt just seems "floppier", and fits itself to ones body better.
Edited by swimjay on 11/20/2008 21:59:19 MST.
Edited by FamilyGuy on 02/19/2015 10:46:49 MST.
I'm a side sleeper who uses Jacksrbetter quilts. I still use bags occasionally but use them open as quilts also. It just plain works better for me for a variety of reasons.
I can fit my wife under my quilt.Irrelevant? Sexist?Nope - a warm body right next to you beats a 1 kg down bag for warmth any day!Cheers
"Nope - a warm body right next to you beats a 1 kg down bag for warmth any day!"My husband can attest to that! One of my "variety of reasons" was hot flashes. I can warm up a tent from 0 to 80 degrees in 3.8 seconds!:-D
Edited by FamilyGuy on 02/19/2015 10:45:40 MST.
Only if you're old enough to 'get' it. ;-)
I just got my Back Country Blanket quilt and I am really happy with it. I'm yet another side sleeper who tosses and turns and occasionally winds up on my stomach. This gives me so much more room/versatility - and because I decided to ignore weight with this item (blasphemy, I know!) I got the medium and can completely wrap and cover myself up in it - SO cozy.
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Google home page a big colorful mystery
John Moe
Sep 14, 2010 Have you been to Google today? Then you've noticed that they're running another special logo. The word "Google" is formed by a bunch of colorful...
Steve Henn
Sep 14, 2010 Nirvana for film buffs. Imagine an online movie rental store with every movie, ever made always in stock - an unlimited number screens and an...
Google search feature no longer hard to find
Larissa Anderson
Sep 14, 2010 Google's RealTime search got its own page today. The service turns offers search results from news sites, blogs, Twitter, Facebook and more in a...
What Gmail Voice will give Google
Sep 14, 2010 Everybody's talking about the new service Google rolled out yesterday - making voice calls through Gmail. Wired's Ryan Single has an...
Gmail now makes phone calls
Larissa Anderson
Sep 14, 2010 Google announced today that Gmail accounts can now take phone calls. For the rest of the year, you can use your Gmail account to call people in the...
No peeking at Facebook pages
Larissa Anderson
Sep 14, 2010 Imagine a world in which it's illegal for an employer to get info about a job applicant on Facebook. That's the world Germany might live in. On...
Leading Thinkers on Net Neutrality
Larissa Anderson
Sep 14, 2010 Net Neutrality is a complicated issue. The recent Google/Verizon policy proposal has raised new questions about the open internet - the idea that...
Google to debut Chrome store for web apps
John Moe
Sep 14, 2010 This is interesting and potentially very significant. At a gaming conference in Cologne, Germany, Google detailed plans to launch a store for...
MID-DAY UPDATE: Goodbye Fannie & Freddie. Hello...?
Bill Radke
Aug 18, 2010 ... What, exactly? China opens bond market to foreigners -- will yuan finally rise? Facebook to try a service that knows where you are Google's...
Net Neutrality: What Are We Fighting For?
Sep 14, 2010 Net Neutrality is a complicated issue. The recent Google/Verizon policy proposal has raised new questions about the open internet - the idea...


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ALBANY — The New York State Police have launched an investigation into allegations that at least one state trooper in Buffalo was involved in promoting a prostitution ring in which female prostitutes were transported from Canada into western New York.
Two people with knowledge of the case said the investigation involves several troopers but is centered on Trooper Titus Taggart, 41, who is assigned to Troop T, which patrols the New York State Thruway. Taggart, a resident of Buffalo, is the son of Arthur L. Taggart, a former State Police colonel who was a special assistant to Thomas Constantine, a former State Police superintendent.
A State Police spokesman confirmed Taggart has been suspended without pay but did not say if any arrests have been made. Josh Vlasto, a spokesman for Gov. Andrew Cuomo, could not be reached for comment.
Click here for photos and link to TU story (the story was first reported on Timesunion.com).
TU Scoop: State Police probe prostitution ring involving troopers
ALBANY — The New York State Police have launched an investigation into allegations that at least one state trooper in Buffalo was involved in promoting a prostitution ring in which female prostitutes were transported from Canada into western New York.
60 Responses
Titus wasn't even smart enough to hold off on his pimpin' career until September of 2013 when he would have been eligible for his pension. Oh, sooooo close…
Would absolutely love to get a look at his performance / attendance / punctuality record.
are ya kidding me? What is up with those FB pix?? If nothing else, I'm thinking total lack of good judgement…
if you go on facebook his pics are public – the ones the TU show here are tame…
Another great scoop by Brendon! In today's day and age why would a public employee, not to mention a trooper use discretion on what he posts on-line? Obviously a total lack of judgement and professionalism.
That trooper be buggin! What a fool! Is he a cop or is he a no good gangsta wanne be? I think the background check didn't work too well on this dude. 41 years old and posting gangsta pics on facebook. Damn fool
This guy is a trooper? wow.
Don't worry he'll take an early retirement, get his full pension ( Which will still be alot more than a real hard working civillian ) Get his full health care. Records and important paperwork will be mysteriously lost and he'll walk.
Give the guy a break, he's only 18.
thug life doh……………
What the….? Oh, they sure are the "elite"……….
I like the picture where he's throwing a gang sign. Is that his second job? Or was that being a trooper?
Do a FOIL request and find out what kind of test score this idiot had when he was hired, bet they by-passed hundreds of higher qualified people to have him disgrace the trooper uniform.
The pride of the New York State Police. This gangsta looks like a piece of garbage… he has now sullied the reputation of a great law enforcement agancy. Why was it allowed to get that bad… why was this thug even hired? His Zone Sergeant had to have some idea that his "Trooper" was in reality a low life piece of trash. This really disgusts me.
I bet some good smart guys were passed over so they could get these guys on the job. Makes you wonder if they ever took the test.
And these guys pull over moms in mini vans to give them tickets for seat belts, cell phones and a variety of other revenue generators while when off duty they want to live the "street life" they never had to deal with first hand. All troopers should have to be city cops before "retiring" to the Northway or Thruway.
The really great thing is that all three of these clowns make over $100,000 a year as troopers. What a waste of our tax dollars.
Another disgraced public employee. I wonder if he would have ever made the force if daddy was not a Colonel??
nice shirt
I wonder how many of his trooper buddies knew of his activities and just stayed quiet.
Sure his papa is proud of him now, or was he also on the take and just never discovered or reported like his gangsta son.
How does this type of activity go on for an extended period of time and not be noticed.
Looks like thuggery to me…as in: cowards…who pays for sex anymore anyhow? Why is it that public officials are the one's that are caught doing stupid stuff? They don't get it…We had a similar situation w/a city councilman in Sch'dy several years ago…I asked the same question: who pays for sex anymore? Gov Spitzer? …he created his own shell company to hide it all…duh! Didn't he realize he could've walked down from the capitol on any given night and go bar hopping @ the myriad of bars in downtown Albany for a sex date? Come on guys…you ain't cool…you're dumb…and soooo unprofessional…the only clothing you'll wear now are your own fake labels that you pay alot of dollars for…no longer the uniform of a proud organization of the NYS Police…you and your ho's deserve what you get…certainly no public respect…
Very sad when poor judgement can hurt your career. The picture on the front page of the TU is priceless, however, and good for a laugh. I'm sure his father is not too pleased now.
This is really weird- the New York Times has a small article about this story in the newspaper this morning , but the gist of it is completely different. Their take? It is a "sex inquiry". "three New York state troopers were suspended on Thursday without pay amid an investigation into whether one of them had organized parties that might have involved prostitution". That makes it sound like they just had a couple of hookers come over for a party NOT that they were involved in a prostitution ring as the TU is reporting.
Why is there such a discrepancy between the two stories? Who's got it right?
Did you see the girls that he's friends with on FB? If they aren't hookers I don't know who is!!!
@20 – being "on the take" commonly refers to accepting a bribe. While this knucklehead may be running a prostitution ring nowhere is the any reference to accepting bribes. Your point may have been valid if you had stuck with the facts.
Just look at the pictures and draw your own conclusions. A fine example he sets for the state police. I wonder if he goes to work with his uniform boots untied like those in the picture? When he aims his gun does he do it sideways? Do the rims on his troop car spin? This is just a major joke. What kind of supervision exists or doesn't exist out there? The sad thing is that because of daddy, I'm sure they'll find some way to drag this on until his retirement date next year so that he can collect about 50k in pension! I'd be curious to see what his score on the trooper test was 18 years ago! Nice job troop!!
this is the reason you don't post stupid pictures on facebook!!!!!!!!
a cop shouldn't be on it at all publicly. if you pissed off the criminal element they know what you, your family and your friennds look like.
he appears to be the criminal himself.
To heck with the legal ramifications, this guy needs jail-time for simply over-accessorizing his already obnoxious SUV.
"Because Poser"
to collect and to serve. that is the role of a trooper in 2012. elite…i think not!
How old is this jerk off ?? he looks like a 17 yr old hood rat,, omg…
NY state is going down the toilet…


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Team KTM off-road racer Shane Watts won't be starting in Tuesday's opening round of the 2002 Grand National Cross-Country Championship, according to a press release sent out by Watts himself. Watts' disappointing start to the new season comes about after he broke his left wrist at a supercross race back in Australia four weeks ago.
"This has been such a disappointing time for me," Watts said in his release. "Today was the first day that I have tried to ride since the injury, and it just wasn't possible. Because of the severe muscle damage I sustained in the original injury, I don't have any strength in my wrist and forearm muscles. It's only three days ago that I actually had the strength to brush my teeth with my left hand. It probably will be round three of the GNCC before I will be able to compete again. I'm just trying to remain positive during the recovery period and come back strong. This decision not to ride has been very difficult, though, as this year I was ready and keen to race and fight for the Championship."


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Free NFL Pick: Carolina Panthers vs. Baltimore Ravens
Carolina Panthers vs. Baltimore Ravens NFL Preview
Date/Time: August 22, 2013 8:00 pm EST
Television: ESPN
NFL Gambling Odds from BetDSI
NFL Betting Favorite: Ravens -3
Total: 41.5
The Carolina Panthers and Baltimore Ravens will get together for a nationally televised preseason game this Thursday night on ESPN. The Ravens have looked good in the preseason thus far despite lots of roster changes. The Panthers are 1-1, but they have looked pretty solid. It's week three of the preseason, which means this will be the game that is most like a regular season game. Let's take a look at both teams.
Game Preview:
Cam Newton didn't play much in week one, but he threw 17 passes and completed eight of them in last week's game. Newton is clearly the guy that makes this offense go, and he'll have to be great if the Panthers are going to compete in a very tough NFC South division. The Panthers played as well as anyone down the stretch last year, but they have to get off to a much better start this season. The running back spot is a position of strength for the Panthers. Tauren Poole and Kenjon Barner have both been good in the preseason, and they should get a lot of looks again in this one.
Carolina's defense was bad at the beginning of the year last year, but their improvement throughout the season helped this team finish very strong. Luke Kuechly has been a terrific addition to this defense, and his ability and leadership skills have really made a difference for this team. I loved the Panthers drafting Star Lotulelei in the first round this year. Lotulelei is dominating force on the defensive line, and I expect big things out of him. This defense has a good chance to be improved once again.
The Baltimore Ravens were crowned Super Bowl Champions at the end of last season, but this year's team has a very different look. Ray Lewis and Ed Reed have been the heart and soul of this franchise for a long time, but they are both gone now. Joe Flacco got a massive contract in the offseason, and he is expected to be the guy to take this team back to the Super Bowl once again. Ray Rice is still one of the most dynamic runners in the NFL, and he'll frustrate defenses for many more years. Anquan Boldin moved on in the offseason, so the Ravens are looking for some wide receivers to step up.
The defense got a nice boost when Elvis Dumervil signed with the team in the offseason. Dumervil gives the team an excellent pass rusher who can make a living in the opponents' backfield. Baltimore's offense has been excellent in the preseason. The Ravens have put up 71 points in two preseason games. Tyrod Taylor has been great as the team's backup quarterback. Torrey Smith caught a 77 yard touchdown pass in the team's 27-23 win over Atlanta last week.
Free NFL Pick: Ravens -3
The Ravens have looked good so far in the preseason. With both teams playing the starters more this game, I think it is Baltimore that has the edge. Look for the Ravens to win and cover.


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7 Hip Readers Commented
Awesome! Thanks!
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i keep saying "im done im done im done"… but thats such a good price ahhh
Is this good for 11 year old boy
Jency, This would be great for an 11 year old, if they are into lego. Mega bloks are a little lesser quality than lego but they really have some cool sets.
Got one, My boy is too young , but i will hold on to it for next Christmas. Thanks!
I picked these up for my DH from my 3 boys! :)


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ACT, egta and EBU invite you to celebrate World Television Day!
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Download the 2014 press release.
2014 press release »
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PEPPTV press release »
The beginnings …
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Read more on UN website »
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Deer Tick members to play Capitol Theatre; Korn to rock Giant Center
John McCauley and Ian O'Neil of Deer Tick will perform at 8 p.m. Jan. 22 at the Capitol Theatre, 50 N. George St. in York. The Shivers and Jonny Corndawg will open the show. Tickets cost $10. For details and … Continue reading
Posted in Celebs, Music, Nightlife Tagged Capitol Theatre, Deer Tick, Disturbed, Giant Center, Hershey, Ian O'Neil, John McCauley, Jonny Corndawg, Korn, Monster Energy, The Shivers, york pa Leave a comment


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Standard Apartment, 1 BedroomMax Occupancy: 7 guests (up to 6 children, 6 infants)
Get an overview of this hotelArt Deco motel in Mangere with free parking
At Airport Travel Air Motor Inn you'll be 2.1 km (1.3 mi) from Mount Mangere and within 5 km (3 mi) of Villa Maria Estate and Dressmart Outlet Shopping Centre. Highlights at this Art Deco motel include free self parking, and in-room kitchens and free WiFi.
You can enjoy plasma TVs with digital channels, and all 20 rooms feature sitting areas, coffee/tea makers, and phones. Kitchens come equipped with refrigerators and microwaves, and room service is also available. Premium bedding and desks are also available. Housekeeping is available once per stay.
This motel has free wired Internet in public areas and a 24-hour front desk. Added amenities include laundry facilities. Cooked-to-order breakfast is available. There's also the convenience of an airport shuttle.
Attractions within a 20-minute drive of this 3-star Mangere motel include One Tree Hill Domain and Eden Park.Information missing or incorrect? Tell us!
Hotel Amenities
Hotel Amenities
Airport Travel Air Motor Inn features laundry facilities and room service (during limited hours). Wired high-speed Internet access is complimentary. Onsite self parking is complimentary.
- Total number of rooms - 20
- Number of floors - 2
- Breakfast available (surcharge)
- Airport transportation
- Free wired high-speed Internet
- 24-hour front desk
- Laundry facilities
- Year Built 1993
- Free self parking
- Number of buildings/towers - 1
Family Friendly Amenities
- Free Wi-Fi
- Kitchen
- Laundry facilities
- Refrigerator
- Microwave
Available in all rooms: Free WiFi
Available in some public areas: Free wired high-speed Internet
Free self parking
Room Amenities
- Coffee/tea maker
- Premium bedding
- Separate sitting area
- Climate control
- Phone
- Kitchen
- Refrigerator
- Microwave
- Housekeeping - once per stay
- Private bathroom
- Shower only
- Hair dryer (on request)
- Iron/ironing board (on request)
- Desk
- Room service (limited hours)
- Digital TV service
- Free WiFi
- Cookware, dishware, and utensils
- Blackout drapes/curtains
- Plasma TV
Where to Eat
Cooked-to-order breakfasts are available for a surcharge.
Room service (during limited hours) is available.
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
- Accessible bathroom
- Accessible parking
Hotel Policies
Check-in time starts at 2 PM
Check-out time is 10 AM
Payment types
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- Breakfast fee: between NZD 10 and NZD 15 per person (approximately)
- Airport shuttle fee: NZD 15 per person (one way)
We should mention
This property offers transfers from the airport. Guests must contact the property with arrival details before travel, using the contact information on the booking confirmation.
National Rating
This property does not have a Qualmark® rating. For the benefit of our customers, we have provided a rating based on our rating system.


text:
Treatment of Vasopressor-induced Ischemia With Botulinum Toxin A
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
The goal of this project is to determine if performing a "chemical sympathectomy" by injecting botulinum toxin A in critically ill patients on vasopressors can treat digital ischemia. This is a prospective, non-randomized pilot study designed to demonstrate proof of concept. We propose to study patients in the intensive care units of Duke Hospital who, secondary to exposure to vasoactive medications used to maintain acceptable blood pressures, have developed signs and symptoms of digital ischemia. A paired T-test will be used to compare pre- and post-injection Laser Doppler measurements for the experimental hand. We will again use a paired t-test to compare the experimental hand against the contralateral control hand. There were no major adverse events reported by the product information sheet or in other related studies of Botox for digital ischemia.
Drug: Injection of botulinum toxin A
|Study Type:
|Study Design:
|Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|Treatment of Vasopressor-induced Ischemia With Botulinum Toxin A
- Perfusion (as Determined by Laser Doppler Measurements) [ Time Frame: 12 months ] [ Designated as safety issue: Yes ]A paired T-test will be used to compare pre- and post-injection Laser Doppler measurements for the experimental hand. We will again use a paired t-test to compare the experimental hand against the contralateral control hand. Results for the experimental and control groups will be plotted and displayed graphically as percent change in Doppler flow (y-axis) and time (x-axis).
- Digital Amputations [ Time Frame: 12 months ] [ Designated as safety issue: No ]The number of digits amputated in our patient cohort is a secondary endpoint of this study. We will use a paired t-test to compare the number of digital amputations in the control versus experimental group.
|Study Start Date:
|March 2012
|Study Completion Date:
|April 2014
|Primary Completion Date:
|April 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Botox injection
Use of botulinum toxin A to determine efficacy in treating vasopressor-induced digital ischemia
Drug: Injection of botulinum toxin A
One-time injection of 100 units of botulinum toxin into hand to perform full chemical digital sympathectomy
Other Name: Botox
|Ages Eligible for Study:
|18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Be admitted to the ICU
- Have digital ischemia and
- Be on a vasopressor infusion
Exclusion Criteria:
- Patients with a history of systemic sclerosis
- Patients actively receiving aminoglycoside antibiotics - aminoglycosides may potentiate the effect of Botox
- Patients who have previously received botulinum toxin (A or B) injections
- Patients with a history of disorders of neuromuscular transmission (e.g myasthenia gravis, Lambert-Eaton, etc.) - Botox may have a lasting effect in these patients given their disorder
- Patients with clinical evidence of an infection in either forearm or hand
- Patients with a history of sensitivity to albumin - Botox is sold in powder form and there is albumin in the formulation
- Pregnancy - Botox is a class C medication
- Rheumatoid Arthritis
- Upper extremity arterio-venous graft or fistula
- Digital necrosis
- History of hand amputation
- Patients whom the intensive care attending physician deems will expire within 48 hours
Please refer to this study by its ClinicalTrials.gov identifier: NCT01483209
|United States, North Carolina
|Duke University Medical Center
|Durham, North Carolina, United States, 27710
|Principal Investigator:
|Cynthia Shortell, MD
|Duke UMC
|Study Director:
|Detlev Erdmann, M.D., Ph. D.
|Duke UMC
No publications provided
|Responsible Party:
|Duke University
|ClinicalTrials.gov Identifier:
|NCT01483209 History of Changes
|Other Study ID Numbers:
|Study First Received:
|November 29, 2011
|Results First Received:
|February 16, 2015
|Last Updated:
|February 16, 2015
|Health Authority:
|United States: Institutional Review Board
Keywords provided by Duke University:
Digital ischemia
Additional relevant MeSH terms:
Pathologic Processes
Botulinum Toxins
Botulinum Toxins, Type A
Vasoconstrictor Agents
Anti-Dyskinesia Agents
Cardiovascular Agents
Central Nervous System Agents
Neuromuscular Agents
Peripheral Nervous System Agents
Pharmacologic Actions
Physiological Effects of Drugs
Therapeutic Uses
ClinicalTrials.gov processed this record on October 09, 2015


text:
Gradwell VoIP is just the right prescription
Case study key facts
|Company name:
|Medical Connections Ltd
|Type of business:
|Healthcare IT - medical imaging software provider
|They needed:
|Exchange and multiple extensions without costly infrastructure
|Gradwell products:
|Multi User VoIP
|Company website:
|Download PDF
As an imaging software provider, Medical Connections supplies the components needed to enable the exchange of medical imaging (X-rays, ultrasound etc). Starting as a home business, new staff were being taken on which meant a new office – and new telephony solution.
"It does what we need very well. It gives us control and the flexibility to be able to work at multiple sites, and also gives us the feel of a larger company."
Dave Harvey, Managing Director
Service and results:
- Multi User VoIP – Improved flexibility. Feature rich with full PABX functionality.
- Keep My Number - Ability to port number from BT.
Flexible working: Medical Connections' Managing Director, Dave Harvey started his business working from home. As the business grew, new premises were sought and Dave found himself researching the market for a new telephony solution, "We'd just increased in size to three people so I wanted multi-line connectivity in the office but also a line at home as I work in both locations. VoIP appeared to be the right solution." When it came to product selection, Dave looked at a number of solutions including devising one himself but explains, "I discovered Gradwell and they ticked all the right boxes at the right price."
Easy connections: After selecting Gradwell VoIP, Dave discovered a number of immediate benefits. The first was the ability to keep the company's original telephone number, which minimised disruption to the business. The second was getting the service started, as Dave recalls, "Both VoIP phones arrived pre-configured and ready to plug in and go, which was very useful." Now Dave and his team know the phones like the back of their hands, as Dave continues, "I added a new number the other day and it was literally functioning within five minutes of doing it!"
Customer care: Now a Gradwell customer for more than two years, Dave regards his overall customer experience as positive, "When you call customer support you get through to a person who's technically competent and knowledgeable – not somebody with a script in a call centre."


text:
Purse with Delica® Glass Seed Beads
-- Designer --
Victoria Johnson-ParrattTo learn more about Victoria Johnson-Parratt, read her jewelry artist success story here
Fire Mountain Gems and Beads 2009 Beading Contest
: : : Materials : : :
Contest designs may have some products from designer's personal collection. Please feel free to substitute similar products from our offerings:
- Seed bead, Delica, glass, opaque black, #11 round
- Seed bead, Delica, glass, matte black, #11 round
- Seed bead, Delica, glass, opaque bright 24Kt gold-plated, #11 round
- Seed bead, Delica, glass, galvanized silver, #11 round
- Thread, Nymo, nylon, size D, black
- Handbags
The pieces featured in the Gallery of Designs are copyrighted designs and are provided for inspiration only. We encourage you to substitute different colors, products and techniques to make the design your own.
Have a question regarding this design idea? Email Customer Service.
Customer Photographs
Fire Mountain Gems and Beads is proud to feature your artwork, and we invite you to submit images of your favorite projects to the Customer photographs section. Here's how you can be included:
- Email your name and attached image to email@example.com
- Please describe your project (e.g.: necklace, bracelet, home decor) and include the main components of your design if known.
- If you've named your piece, please let us know!
- Photos should be a minimum of 500x500 pixels or (6.94 inches)
- To best showcase your artwork, place dark designs on a ligh background and light artwork on a dark background
- For additional photography tips, click here.
If you have any questions or concerns regarding the artistic credit of the artwork displayed here, please contact us at email@example.com.


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- Thursday, May 12, 2011
San Francisco Cinematheque: 50 Years
Date + TimeThursday, May 12, 2011
7:00 p.m.
LocationPhyllis Wattis Theater
Crossroads is SF Cinematheque's annual film festival showcasing avant-garde works from emerging and established filmmakers. This year's festival opens with the culminating screening of Cinematheque's Radical Light series and a celebration of the organization's 50th anniversary. The program includes rarities, rediscovered gems, and restored masterpieces from across the history of Bay Area film. Following tonight's opening at SFMOMA, Crossroads continues through May 15 at the Victoria Theatre.
Admission + Ticketing
$10 general; $7 SFMOMA and San Francisco Cinematheque members, students, and seniors.Buy tickets
Image: Christopher Harris, 28.IV.81 (Bedouin Spark) (still), 2008; courtesy of San Francisco Cinematheque


text:
Kashmir snow festival attracts tourists
In a bid to promote winter destinations and attract tourists in Jammu and Kashmir, the state government recently organised a two-day snow festival in Pahalgam District.
State Tourism Minister Ghulam Ahmad Mir inaugurated the two-day festival, which kickstarted on Tuesday.
Although tourists throng Pahalgam during the summers, the state government aims to increase tourist inflow during the winters as well through the snow festival.
"For the last few years, tourists were visiting limited destinations, and because of such limitations, the arrival of tourists was on decline. If tourists were coming,they use to leave in three days, cutting their trip short.
Our plans are to engage tourists for at least ten days," said Mir. The festival initiated a new trend by attracting more tourists.
Despite freezing temperatures, rugby players wooed audience. "If we see, earlier in Pahalgam, sports activities were very less. But now, I think because of the festival, there is lot of tourist inflow.
Tourists are coming to us and taking photographs. In terms of tourism, a new trend is developing," said rugby player, Irfan Ahmad.
During the snow festival, various winter sports like snow rugby, skiing and snow throwing championship were held. "It feels good to be here. I think snow festival should be held every time and even after snowfall, adventurous sports like rock climbing should be promoted for the benefit of people," said a tourist, Sunita.
Local residents welcomed this step taken by the tourism department as this will bring tourists to Pahalgam in winter season also, which is also generate employment opportunities.
(Posted on 28-02-2014)
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Best shave ever!
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The Thoracic Oncology Program at the University of Maryland Medical Center
is one of the pioneering institutions nationally using a finely tuned multidisciplinary
approach to the treatment of malignant mesothelioma and other asbestos-related
diseases. With our multidisciplinary care program, patients have access to all
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Malignant mesothelioma, an uncommon form of cancer, is a disease in which cancer
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mesothelioma is often simply called mesothelioma.
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Pleural mesothelioma is a malignant mesothelioma that spreads within the chest
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Asbestos exposure is the most common risk factor associated with mesothelioma.
Asbestos refers to a family of magnesium-silicate mineral fibers that have been
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A history of asbestos exposure is found in 80 percent of patients who present
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Did Arunachalam Muruganantham go to a design school?
Read two interesting articles on design today morning, surprisingly both from the famous magazine Fastcompany. For people who have not visited Fastcompany it's a must visit site. The have two dedicated channels Co Design (Covers design in general) and Co.exist is a recent addition that covers social innovations.
Now to the interesting articles, the first article is about Facebook timeline since people have written a lot about it. I am going to write about this wonderful entrepreneur in India who designed a system to manufacture low cost sanitary napkins for Indian women.
Arunachalam Muruganantham :
Honestly Arunchalam reminds me of James Dyson who famously built more than 5000 prototypes of his designs before making the perfect vacuum cleaner. Arunchalam went a step ahead to validate his low cost sanitary napkin designs; he wore panties, used a sanitary napkin himself, divorced by his wife, abandoned by his own mother and was ridiculed continuously by the public. But thanks to the pain he went through now more than 88% of Indian women can now buy a low cost sanitary napkin, roughly $0.25 for 8 napkins. Arunchalam designed anew machine that can make these low cost sanitary napkins. According to a report by Neilson that more than 88% of women in India use rags, newspapers and dried leaves during their periods.
Unlike Dyson who is now a billionaire Arunachalam decided not to sell his product commercially. At this point Arunchalam overtakes Dyson and becomes a hero. Though Arunachalam was SSLC drop out If you look closely at this case study at Co.exist there are many interesting takeaways for a designer.
Empathize with your user:
Arunachalam took extreme steps to validate his designs with only one goal his mind "To make sure that women who eventually used it felt comfortable using it". As designers its vital to have the same goal in our mind – will the end user be comfortable using our product.
Believe in your Design:
The most important quality that differentiates between a good designer and a great designer. Arunchalam believed in his design solution and worked hard to achieve the final design, at no point he doubted his decisions. As designers we need to convince our stakeholders of our vision every single day. We cannot convince others unless we believe in our own designs. This does not mean to that designers can act cocky and get away with it.
Vision Vs Ideas
Arunachalam had a vision in his own words "My vision is to make India a 100% napkin-using country. " By this he thought of a whole new product system, starting from materials, production, socio – economic barriers, cultural differences, technology, logistics and finally the manpower to produce the napkins. He did not just design product but whole new product system. He had one complete vision and he innovated with exciting ideas throughout to achieve it. Designers have great ideas but what is missing converting an idea into a product vision. By spending little more time and hard work we can turn an idea into a successful product or a service that can have greater impact on the society. Apple did not want people to listen to music but Apple wanted people to enjoy music and Apple designed a product system that changed the way we consumed music.
That's it for now, please send in your comments, see you soon :)
Read the article at : http://www.fastcoexist.com/1679008/an-indian-inventor-disrupts-the-period-industry
Visit Arunchalam' s website : http://newinventions.in/index.aspx


text:
Apple to refund USD 32.5mn to parents whose kids made in-app purchases without consent
Apple is reportedly going to refund consumers at least a sum of 32.5 million dollars to settle a federal case involving in-app purchases that kids made without seeking parental permission.
The Federal Trade Commission (FTC) ordered the tech giant to make full refunds for any such in-app purchases made by kids using mobile phones and other devices or any other charges by accident or without parents' permission.
According to Fox News, Apple would be required to change its billing practices to make it more obvious that an actual purchase is taking place during the course of the game or app.
FTC head, Edith Ramirez said that the settlement involves mobile apps and charges that shot up to even hundreds and thousands of dollars in some cases when kids bought things such as virtual currency or dragon food.
The complaint stated that when parents entered their password while a child played a game, Apple did not make it clear that that they unwittingly may be buying something in the game the child had clicked on, such as a chest of gems or treats for a virtual pet, the report said.
The commission further stated that parents were not told that once entering the password would open a 15-minute window in which kids could make unlimited purchases without further need of any password.
The tech giant has been ordered to modify its rules until Mar. 31 and come up with a billing system that ensures the company obtains consumers' informed consent before billing them for in-app purchases, the report added.
(Posted on 16-01-2014)
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