text:
When traveling in Thailand, hiring a Thai car can be an enjoyable and relatively inexpensive way of getting about. A Thailand rental car with a driver/guide is marginally more expensive, but is perhaps a better idea as it will help you avoid many of the problems associated with driving yourself.
Avis, Hertz and other international car hire agencies are well represented in Thailand, and there are also many local companies that rent cars at competitive rates. In fact, most local companies are cheaper, but have the disadvantage that the cars may not be properly insured (even if they tell you otherwise). Your insurance from home might not cover an accident while driving a Thai rental car or motorbike in Thailand, so it's worth checking that out before you leave home. Furthermore, many rental companies will not rent a Thai car to drivers who do not have an international driving license. If they do, they may stipulate that the insurance on the car is not valid. While it is technically legal to drive in Thailand with a valid foreign driver's license, having an international license will make renting and driving a Thai car potentially less problematic.
One-way rental between destinations (e.g. Bangkok-Chiang Mai) is a possibility, but you should expect to pay a drop-off fee. It's a good idea to always fill up the tank before you bring the car back too, as petrol is cheaper at the station near most airports and the fee you might otherwise be charged is likely to be expensive.
Once it was common for Thailand car rentals to require you to leave your passport as a deposit for any vehicle that you rent. In lieu of this, nowadays, most rental car companies will ask for a credit card that they will carbon copy with a deposit/charge of perhaps 50,000 baht (roughly 1,500 US dollars). Some places will let you leave travelers cheques or cash instead (local rental car agencies are generally more flexible than international ones). However, for motorbike rentals it's almost always your passport that you must leave behind. Bear in mind that if you have any sort of problem and have left your passport as collateral, you will be in a very weak position when it comes to negotiating how much the damage costs. Your embassy and/or the police may be able to help you, but don't count on it.
Check a vehicle thoroughly before hiring it as they are not always in pristine condition, particularly the cheaper ones. Point out any existing damage or scratches before you hire, or don't be surprised when they try to charge you for them later. When hiring a motorbike, consider bringing along your own padlock to lock the front tire. It isn't unheard of that unscrupulous motorbike rental companies "steal" their own bikes so as to charge you for "forgetting" to lock it properly.
For most people, hiring a car and driving in Bangkok would be little short of a nightmare. The traffic is some of the worst in the world, roads have confusing signage, and some of the driving standards exhibited are questionable to say the least. For daytrips in and around Bangkok, hiring a car with a driver or using taxis would be a much better idea. That said, the traffic on Phuket or Samui is not considerably any more sane: road lanes are not well painted, cars drive erratically, and many roads are frighteningly narrow.
Hiring a motorbike is quite a common activity, particularly on the southern islands and in some of the northern towns. Especially in the north, this is a great way to get out into the countryside to see the 'real' Thailand. It's possible to hire motorbikes in Bangkok too, but inadvisable unless you are a very experienced rider - accidents are all too common.
Places such as Koh Samui and Pattaya have a lot of foreigners renting motorbikes who have never ridden one before, which can also contribute to hazardous driving conditions. You should also expect to be stopped at least once by the Thai police if you do a lot of riding, as you are technically breaking the law if you:
* Don't have a valid international driving license with motorcycle entitlement.
* Don't have a valid health insurance policy (even though Thai health insurance policies often don't cover motorbike accidents!)
* Aren't wearing a helmet.
* Don't carry your passport around with you at all times -obviously a bit of a problem if you left it as a deposit.
Some of the roads on Koh Samui and Koh Phangan are very dangerous, particularly the road from Thong Sala to Haad Rin on Koh Phangan. Be careful, as accidents in this area are very, very common – in fact, motorbike accidents are the number one cause of deaths of foreigners in Thailand. If you've never ridden before, some of these roads really aren't the best places to learn. At the very least, wear a helmet (it's the law) and wear jeans and close toed shoes.
If you have to misfortune to get into an accident, it's likely to be judged as your fault (even if it wasn't) and you will be expected to pay (on the spot) for any damage caused (to vehicles and people). If someone is injured, the asking amount will be increased to cover the treatment costs - these amounts are definitely up for negotiation, strange as it may seem. Any serious injuries and deaths will definitely involve the police being called - you may still be able to get out of trouble by paying enough money, but it's not certain. Police often act as negotiators in the settlement of accident compensation. Oddly enough police tend to give the benefit of the doubt to those who report an accident. It's a gamble any time the police get involved, but if they are going to eventually become involved, it may be better to be the first one to calmly report that they have been the victim of another person's negligence.
Travel around Thailand
- Transportation Options
- » Airlines
- » Airport Shuttle
- » Bus & Coach
- » Custom Transfers
- » Car & Vehicle Hire
- » Taxis
- » Bangkok BTS Skytrain
- » Underground Bangkok MRT Subway
- » Airport Rail Link
- » Train
- » Tuk tuks
- » Boats & Yachts
- » Motorcycle and Scooter Rentals
- » Cycling
- » Motorhomes
- » Driving in Thailand
- » Private Chaters
- Traveling in Thailand
- Driving Routes
- Thailand Airports
- Tourist Information Centers
Operators Listing
Browse Car & Vehicle Hire Listing Here.
When traveling in Thailand, hiring a Thai car can be an enjoyable and relatively inexpensive way of getting about. A Thailand rental car with a driver/guide is marginally more expensive, but is perhaps a better idea as it will help you avoid many of the problems associated with driving yourself.


text:
10 U.S. Code § 8632, 8633 - Repealed.
Effective Date of Repeal
Repeal effective Nov. 1, 1962, see section 15 ofPub. L. 87–649, set out as an Effective Date note preceding section 101 of Title 37, Pay and Allowances of the Uniformed Services.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.

subset: commoncrawl


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- Red Bull USA - Sports & Entertainment News | Teams & Athletes
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- Jill Kintner in the mud at the UCI Downhill World Cup in Austria
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Compact digital still camera with built-in flash, 3.3x Optical & 4x Digital & 13x Combined Zoom
10.0 Megapixel, 1/2.3-inch type Charge Coupled Device (CCD)
Total Pixels
Approx. 10.6 Megapixels
Effective Pixels
Approx. 10.0 Megapixels
Focal Length
6.6 (W) - 21.6 (T)mm - 35mm (film equivalent: 37 - 122mm)
Digital Zoom
Focusing Range
Normal: 0.4 in. (1cm) - infinity (W), 9.8 in. (25cm) - infinity (T)
Macro: 0.4 in. - 1.6 ft. (1-50cm) (W), 9.8 in. - 1.6 ft. (25 - 50cm) (T)
Autofocus System
TTL Autofocus
Optical Viewfinder
LCD Monitor
2.5-inch TFT color
LCD Pixels
Approx. 115,000 dots
LCD Coverage
Approx. 100%
Maximum Aperture
f/3.0(W) - f/5.8 (T)
Shutter Speed
1 - 1/2000 sec.
15 - 1/2000 sec. (Total shutter speed range)
Auto, ISO 100/200/400/800/1600
Low Light: ISO 500-3200
Light Metering Method
Evaluative, Center-weighted average, Spot
Exposure Control Method
AE Lock
Exposure Compensation
+/-2 stops in 1/3-stop increments
White Balance Control
Auto*, Daylight, Cloudy, Tungsten, Fluorescent, Fluorescent H, Custom
*Facial color is evaluated in Face AiAF.
Built-in Flash
Auto, On, Slow Synchro, Off
Flash Range
12 in.-9.8 ft. (W), 12 in.-6.6 ft. (T) (30cm-3.0m (W), 30cm-2.0m (T))
Recycling Time
10 sec. or less (battery voltage: 3.0 V)
Flash Exposure Compensation
Shooting Modes
P, Auto, Scene*1, Movie*2
*1 Blur Reduction, Portrait, Kids & Pets, Face Self-timer, Low Light, Super Vivid, Poster Effect, Beach, Foliage, Snow, Sunset, Fireworks, Long Shutter
*2 Standard
Photo Effects
My Colors Off, Vivid, Neutral, Sepia, Black & White, Custom** Adjustment of contrast, sharpness and saturation available.
Self Timer
Approx. 10-sec delay, approx. 2-sec. delay, custom*
* Delay time (0-15 sec. in one-second increments), 20/25/30 sec.) and number of shots (1-10 shots (in one-shot increments)) can be specified.
Wireless Control
Continuous Shooting
Approx. 0.8 shots/sec. (in P mode)
Approx. 2.2 shots/sec (in Low Light mode or Blur Reduction)
Storage Media
SD/SDHC/SDXC Memory Card, MultiMediaCard, MMC Plus Card, HC MMC Plus Card
File Format
Design rule for camera file system, DPOF Version 1.1 compliant
Image Recording Format
Normal, Fine
JPEG Compression Mode
Still Image: Exif 2.3 (JPEG)
Movie: AVI (Image: Motion JPEG; Audio: WAVE (Monaural))
Number of Recording Pixels
Still Images: 3648 x 2736 (Large), 2816 x 2112 (Medium 1), 1600 x 1200 (Medium 2), 640 x 480 (Small), 3648 x 2048 (Widescreen)
Image data
Movie data
Playback Modes File
Still Image: Single, Index, Magnification (approx. 2x-10x)
Videos: Normal playback*1, slow motion*2, skip backward*3, previous frame*4, next frame*4, skip forward*3
Erase Modes
Still Image: single image, all imagesVideo: any video file
Computer Interface
Hi-Speed USB 2.0 (mini-B jack)
Video Out
Audio Out
Memory card slot; direct connection to Canon SELPHY Compact Photo Printers, PIXMA Inkjet Photo Printers and PictBridge-compatible printers via camera's USB 2.0 Hi-Speed cable
Power Source
1. 2 AA Alkaline batteries (NiMH batteries NB-3AH x2) 2. Compact Power Adapter CA-PS800 (Used together with DC Coupler DR-DC10)
Shooting Capacity
Alkaline batteries: approx. 300 shots
AA NiMH batteries: approx. 500 shots
Playback Time
Alkaline batteries: approx. 11 hours
AA NiMH batteries: approx. 12 hours
Operating Temperature
Operating Humidity
Dimensions (W x H x D)
3.71 x 2.43 x 1.23 in. / 94.3 x 61.6 x 31.2mm
Approx. 6.56 oz. / 186g (Including the battery and memory card)
Approx. 4.87 oz. / 138g (camera body only)
All data are based on Canon's Standard Test Method. Subject to change without notice.
Canon, DIGIC, ELPH, PIXMA, and PowerShot and SELPHY are registered trademarks of Canon Inc. in the United States and may also be registered trademarks or trademarks in other countries. Microsoft, Windows and Windows Vista are trademarks or registered trademarks of Microsoft Corporation in the United States and/or other countries. Mac is a trademark of Apple, Inc., registered in the United States and other countries. All other products and brand names are registered trademarks, trademarks or service marks of their respective owners in the United States and/or other countries.


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- Northern New York Newspapers
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New York Air Brake management and the Machinists union agreed Sunday to go back to the negotiating table for two weeks. The move, occurring the day after union members rejected a contract offer entailing wage and benefit cuts, puts off the threat of a Tuesday strike.
I really am optimistic that well reach an agreement at the end of two weeks, Air Brake President Michael J. Hawthorne said Sunday.
Air Brake and International Association of Machinists and Aerospace Workers Local 761, which represents 150 employees at the Watertown manufacturer, also agreed Sunday not to divulge information from negotiations to the media until an agreement is reached on a new three-year contract, Mr. Hawthorne said. He declined to comment about the unions opposition to the offer, which the rank and file voted to reject Saturday following a daylong meeting at the Northpole fire station.
Air Brake has proposed to cut union members pay by from 59 cents to as much as $4.15 an hour, depending on job classification. The company has proposed an incentive plan based on performance in exchange for those cuts. The average union wage at Air Brake is $20.88, the union reported.
Also opposed by the union were contract provisions ending the unions pension plan, replacing it with a 401(k); scrapping seniority protections, and granting the company authority to hire nonunion workers. The latter provision would enable the company to hire part-time workers with no health benefits.
Meetings over the next two weeks will extend negotiations that began about six weeks ago. The union on Saturday rejected what Air Brake previously described as its final offer, before its decision Sunday to resume talks.
John B. Carr, regional spokesman for the union, declined to respond Sunday about talks between the two parties.
Thousands of readers like you have made Northern New York Newspapers the number one ranked website* for local news and sports coverage in the north country.
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This is true. And just like the Wizard of Oz, we're not supposed to look behind the curtain. The wiz 'knows best,' and he won't tolerate the idea of too much truth.
The Wizard's system is extremely profitable, it is deeply entrenched, it requires silence on many levels, and it doesn't hesitate to sacrifice those who threaten the system's status quo.
It would make a great movie, if Hollywood had any integrity. It would foster many TV programs, if the media wasn't a bloated, unworthy prostitute.
Stealth systems work best in an artificial environment where 'leaders' are corrupt and citizens are 'managed' by those who 'know best' and expect to be highly paid for doing as little as possible.
Sounds like Washington, doesn't it?
Reader Justen Posted in A New Paradigm:
I know sometimes it feels like you're only preaching to the choir, or that it's all falling on deaf ears, but remember—we all used to be statist drones once. Very few people have the privilege of being born into a family that counter-educates them; we all have to figure this stuff out on our own. I try not to get frustrated with the empty-headed ones. Either they'll come around eventually or they'll be murdered by their own state (directly with a gun or indirectly through starvation, damaged health, and suicide). Spreading the word is our way of paying forward the gift of knowledge that was given to us, but we have no obligation to help anyone, only the desire.
Reader Kevin Posted in A New Paradigm:
Roosevelt said in his 1930 Home Rule speech that when nearly all power was centralized in Washington DC, America would have an "Oligarchy masquerading as a Democracy". Of course, Roosevelt and the Democratic Presidential platform of 1932 called for downsizing the Hoover Administration's Big Government policies. Roosevelt lied and did a 180, expanding government to "save the economy", paralleling what Hitler was doing in Germany. Hitler even sent a letter, through our ambassador to Germany, to Roosevelt thanking him for the job he was doing with America. As F.A. Hayek warned in his "Road to Serfdom, socialism, collectivism, and central planning were the common thread between communism, fascism, the New Deal, etc. It doesn't really matter what you call it, when the central government controls it, it's totalitarian.
Our government has been under the Sustainable Development, United Nations Agenda 21 program since 1993, which calls for worldwide population control and reduction. The right and left media are ignoring this. Like the quiet children in the other room, it's what you don't hear about that you should worry most about.
With over 600 pages, "AIDS, the Crime Beyond Belief", by Don Scott is an excellent book to understand America's population reduction programs since 1953. Of course, the book covers the development of AIDS by our government, which was working with Rockefeller and other eugenics-minded people, such as Kissinger. One AIDS strain was developed in New Orleans, the other in Africa—one strain was put in the Hepatitis B shots given to the Gay population in San Francisco (75 percent that took the vaccinations developed AIDs), the other in the Small Pox Vaccinations in Africa—many blacks were forced at gun point to take these vaccinations–8000 blacks a day are dying of AIDs in Africa. If you understand that Myco Plasma is one of the co-factors in AIDS (our government even patented Myco Plasma to control studies on it), and that 30 percent of the black population have it in their bodies (as compared to 2 percent of the white population), then you realize AIDS really was targeted at the black population.


text:
Akribos XXIV
Men's Stainless Steel & Gold Watch
- Color:
- gold
Qty: 1
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- 3
Please select an available size.
Please select a size.
- Round stainless steel case with silver tone dial, date window at 4 o'clock, chronograph subdial at 3, 6, and 9 o'clock, and yellow gold ionic plated stainless steel bezel
- Stainless steel and yellow gold ionic plated stainless steel bracelet with push button deployment clasp closure
- Swiss quartz movement
- Water resistance tested at 50M
- Case measures 43mm (1.69 inches) wide
- Bracelet measures 22mm (0.86 inches) wide
- 2 year limited manufacturer warranty
- Note: IP or ionic plating is a process that is primarily used for wear resistance and corrosion protection
Material: Yellow gold ionic plated stainless steel and stainless steel
Brand: Akribos XXIV
Origin: Imported


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Green Eggs and Hamby Dr. Seuss
Synopses & Reviews
Publisher Comments:
How do you like your green eggs and ham? In a house with a mouse? Or maybe on a boat with a goat? Beginning readers are offered these ingenious choices, and so much more, courtesy of the ever-enthusiastic Sam-I-am.
Dr. Seuss turns 50 simple words into magic in this time-honored classic.
Sam-I-am won't give up! He keeps trying to get the grumpy grown-up in the story to taste green eggs and ham.
No matter how Sam-I-am presents the green eggs and ham (in a box, with a fox, in the rain, on a train), the curmudgeon refuses to try them.
Finally, Sam-I-am's pesky persistence pays off. A crowd of open-mouthed onlookers watch in suspense as the old grouch takes a bite. And?
...SAY! The old sourpuss's face is wreathed in smiles as he gratefully acknowledges, "I do so like green eggs and ham. Thank you, thank you, Sam-I-am!"
For nearly fifty years, Green Eggs and Ham has delighted young and old with its wildly imaginative simplicity — all the while, introducing generations of children to the joy of reading.
"Limited vocabulary but unlimited exuberance of illustration." School Library Journal
Sam-I-Am mounts a determined campaign to convince another Seuss character to eat a plate of green eggs and ham.
With his unmistakable characters and signature rhymes, Dr. Seuss's beloved Beginner Book has cemented it's place as a children's classic. Follow Sam I Am as he tries to convince an acquaintance that green eggs and ham is, indeed, a delectable meal to be savored everywhere and every way.
About the Author
"A person's a person, no matter how small," Theodor Seuss Geisel, a.k.a. Dr. Seuss, would say. "Children want the same things we want. To laugh, to be challenged, to be entertained and delighted."
Brilliant, playful, and always respectful of children, Dr. Seuss charmed his way into the consciousness of four generations of youngsters and parents. In the process, he helped millions of kids learn to read.
Dr. Seuss was born Theodor Geisel in Springfield, Massachusetts, on March 2, 1904. After graduating from Dartmouth College in 1925, he went to Oxford University, intending to acquire a doctorate in literature. At Oxford, Geisel met Helen Palmer, whom he wed in 1927. Upon his return to America later that year, Geisel published cartoons and humorous articles for Judge, the leading humor magazine in America at that time. His cartoons also appeared in major magazines such as Life, Vanity Fair, and Liberty. Geisel gained national exposure when he won an advertising contract for an insecticide called Flit. He coined the phrase, "Quick, Henry, the Flit!" which became a popular expression.
Geisel published his first children's book, And to Think That I Saw It on Mulberry Street, in 1937, after 27 publishers rejected it.
Winner of the Pulitzer Prize in 1984, an Academy Award, three Emmy Awards, three Grammy Awards, and three Caldecott Honors, Geisel wrote and illustrated 44 books. While Theodor Geisel died on September 24, 1991, Dr. Seuss lives on, inspiring generations of children of all ages to explore the joys of reading.
Series Description
Back in 1957, Theodor Geisel responded to an article in Life magazine that lamented the use of boring reading primers in schools. Using the pseudonym of "Dr. Seuss" (Seuss was Geisel's middle name) and only 223 words, Geisel created a replacement for those dull primers: The Cat in the Hat. The instant success of the book prompted Geisel and his wife to found Beginner Books, and Geisel wrote 44 books in this series. These affordable hardcover books combine large print, easy vocabulary, and large, bright illustrations in stories kids will want to read again and again. Grades 1 - Grades 2.
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OLEAN, NY - New York State Senator Catherine Young (R-Olean) says she was unaware until recently that she and her husband had, for more than a decade, been improperly claiming a Basic STAR property tax exemption on both their primary residence in Olean, and a condominium they own in an Albany suburb, which Sen. Young uses when working at the state capitol.
In a statement released to Two On Your Side this morning, Senator Young indicated her husband was responsible for the error.
"Like many families, my husband handles all of our financial matters. I just found out about this. I took immediate action to correct it. I have filed the appropriate legal documents to cancel the STAR (on the North Greenbush condo) and repay the full amount owed. The assessor is calculating how much and as soon as I have the assessor's figures, it will be paid in full."
The Albany Times Union newspaper reports that an aide to the Senator said she learned of the dual exemption over the weekend "during a casual conversation with her husband."
Late this afternoon, however, Young's office released the following e-mail, which it says was sent to the Senator from North Greenbush Assessor John Harkin, and in which he indicates the Youngs were not at fault for what he classifies as an unfortunate mixup.
"I have researched the STAR exemption on the property in the Town of North Greenbush and found that the exemption was on the property prior to your purchasing it. I have the STAR application confirming the date of the exemption sent in by the previous owner. The Assessor sent a STAR application to the North Greenbush address after your purchase however it was was returned by the Post Office. She unfortunately did not remove the exemption off the property and the exemption has remained on the property erroneously.
While a careful reading of the School Tax bill would have revealed this fact it appears there was no affirmation action taken by either You or your Husband to claim this STAR exemption. It certainly appears to me that this was an honest error by both parties.
Sorry for any troubles this has certainly caused you in the past few days. If I can be of further help please do not hesitate to call me.
Young's press secretary told WGRZ-TV that Young was unavailable to speak with us on Thursday.
City of Olean Assessor Nancy Champlin confirmed for Channel 2 News that she had been contacted by the NYS Office of Real Property Services (ORPS) within the past two weeks, which e-mailed to her a list of several properties where it appeared that the owners had filed for STAR exemptions on more than one property.
"They have been doing spot checks like this for the past few years," Champlin said.
The STAR program allows taxpayers to exempt a portion of their home's assessed value from school taxes. But it is only allowed for the taxpayer's owner-occupied, primary residence.
This "spot check", as Champlin described it, revealed the Young's had been claiming a STAR Exemption for both their home in Olean, and the condo in North Greenbush since 2001.
Just last week, NYS Comptroller Thomas DiNapoli released an audit, suggesting that the STAR program is rife with incidents of "double dipping".
The audit sampled STAR exemptions for 6,500 properties, and estimated that one out of every five, or 20 percent, had been granted improperly...costing the state roughly $13 million.
WGRZ-TV, wgrz.com


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Murad Fine Hair Starter Kit
We know you want the goods as soon as possible, which is why orders received by 3pm ET leave our warehouse the very same day. We'll send you an email that day to confirm shipment and the email will include your tracking information.
Our warehouse is closed Saturday & Sunday, so orders received after 3pm ET on Fridays will not ship out until Monday.
Based on 3 Reviews
CliffCanadaIt Works For MeMy hair began to fall at a rather alarming rate several years ago. I had no idea what to try, so I tried a doctor-recommended product (mynoxidil) with poor results.
Then my stylist recommended to try Murad, She applied the Fine-to-Thinning Hair Serum when she gave me a scalp massage before a cut. It really made my scalp tingle, as the serum increased circulation. I've been using it ever since then.
I see some postings about the serum falling off the side of the head. It's easily avoided by putting a few drops on, then patting it down with your hand to spread it on the scalp. To do the sides, just tilt your head a bit before applying. Once I've done the sides, top, and back of the crown, I massage the scalp for a few minutes.
The conditioner works well too. Don't worry about seeing redness, that's just the increased blood circulation. I've been using Murad for years and it works for me!
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Olivia E.USAHairBlondeFine or Thin HairCan't Beat This Murad ProductSeven months ago I got really really sick. I got sepsis which is an infection in the blood. Three months later I had an acute case of hair loss. It was all in the front. It got so bad you could see light reflecting off my scalp. My only recourse was to go to a wig store. The gal there sold me this kit at a considerable increase in cost than at Folica. When I needed to refill my product, I googled it and found that Folica had it for a significant decrease in cost. As for my hair, it is definately much better. Hair has grown in and I've had to redye my new hair as I am all grey naturally. I still wear wigs but sometimes will run to the store without wearing one. My wig gal said Murad had a guarentee that I would regrow hair and I have. What more can I say? Good stuff from a great company.6 out of 6 shoppers thought this review was helpful.
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JoshuaSan Diego Ca USA3 MonthsOver the past couple of years I noticed my hair was beginning to thin. Not much, but it was bothering me. I'm sure like many guys, going bald just isn't something I want to happen to me. So I did some research and purchased the Murad shampoo and conditioner. I have never used the serum. After three months of using it 6 days or more a week I have noticed fuller thicker hair. I can no longer easily see my scalp through my hair. I noticed that in pictures with flash used it hard to see my scalp as well. I'm going to continue to use the Murad line of products indefinitely because I personally believe it works to thicken your hair beginning at the scalp.27 out of 28 shoppers thought this review was helpful.
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To go with 'China-economy-growth,ANALYSIS' by Kelly Olsen This... Fotografia de notíciasAdulto,China,Criança,Economia,Finanças,Fábrica,Horizontal,Huaibei,Ilustração,Indústria Têxtil,Maquinaria,Mulheres,Máquina de Costura,Província de Anhui,Raparigas,Trabalhar,Técnica Ilustrativa,VestuárioPhotographer STRCollection: AFP 2013 AFPTo go with 'China-economy-growth,ANALYSIS' by Kelly Olsen This picture taken on January 10, 2013 shows laborers working in a clothing factory in Huaibei, central China's Anhui province. China's economy is poised finally to end a long downward trend in 2013, economists polled by AFP say, as the new communist leadership vows to retool the nation's investment-led development model and promote a 'happy life' for all. CHINA OUT AFP PHOTO (Photo credit should read STR/AFP/Getty Images)


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Snyder To Direct Next Star Wars Project? (Filmofilia)Awesome Bad Movie: Biohazard (FilmDrunk)Love N' Licks Are Terrifying (Manofest)Watch Wolverine Free Of Charge If You're a Douchebag (Pajiba)Debra A Is for Ass (GorillaMask)Chewbacca On Guitar? (IAmBored)Dangerous Child Prodigies (Cracked)More On Clash Of The Titans (DreadCentral)Pornography: A Timeline (Holytaco)Maria Swan's Rack (BustedCoverage)Denise Milani Goes Topless! (Uncoached)Legend Of Zelda Movie Trailer: April Fools? (Unreality)Ring Ring Phone Call! (TomOatmeal)How NOT To Transport An Air Conditioner (NothingToxic)The Hottest Women In The World (Chickipedia)
The new Taking of Pelham 1 2 3 trailer went up today on Myspace, and it's got enough Travolta-on-Denzel action to make Oprah's live audience collectively explode from a freak mass orgasm. The film is slated for a June 12th, 2009. Gentlemen, lock up your wives and girlfriends lest they stampede children on the way to the theater. Check out the clip after the jump to see what we're up against.
The Hollywood reporter posted an article about Twitter going Hollywood, with stars and behind-the-scenes talent starting to constantly update their Twitter accounts, giving us movie fans unprecedented access into the inner workings of filmmaking – no matter how mundane the details. Ashton Kutcher was reported to have tweeted about the pitfalls of his stunt double showing up to set with a shaved chest. Iron Man 2 director Jon Favreau posted the following last month: "Directing is about waking up every night at 4 a.m., exhausted, and not being able to fall back asleep because your brain is screaming at you." Directing sounds a lot like editing a blog. The brain part sounds a lot like my self-loathing, which, incidentally looks a lot like Danny Devito, for whatever reason. But I would argue all this tweeting strips away the artifice that makes movies fun in the first place.
WASHINGTON – President Barack Obama on Wednesday, April 1st backed down from his initial order of 4,000 more military troops in Afghanistan, vowing instead to "still disrupt, dismantle and defeat"…
April Fool's Day is a boon for movie sites, since we thrive so much on rumors anyway. To me, a great April Fool's joke is one where no one gets hurt, and you don't have to say "April Fools!" at any point in the execution, because it's obvious by the end of it. Sort of like the entire run of Saved By the Bell: The College Years, which was so good, it debuted in September or something (don't quote me on that). Nonetheless, movie sites try their darnedest to find a great setup for a rug pull. Here are a couple noble efforts, followed by some real news, done by real, hard hitting journalists who ask the tough questions rather than just make up answers willy-nilly. You know who I'm talking about, Variety. Iron Man 2 Title Worse Than Spider-Man: Turn Off the Dark (Cinematical) Matrix Series Gets Fourth Film (/Film)Okay enough of the fakery… everything else is REAL. Del Toro's Mimic Gets Special Edition DVD (Twitch)Myspace launches first game show with "BFF" (Variety)60 Robots in Transformers 2 (AICN)Will Arnett & Michael Shannon join cast of Jonah Hex (ComingSoon)Kevin Spacey is the Father of Invention (Empire)
Zach Galifianakis is still the funniest comedian I've ever seen live. Ed Helms is still the funniest part about NBC's The Office. And Bradley Cooper is still the funniest actor to make out with Michael Ian Black in Wet Hot American Summer. All three guys star in The Hangover, the trailer for which has been out a little while, but we hadn't posted it yet. I'm hoping this movie gives both Mike Tyson and Phil Collins' "No Jacket Required" album the comeback both parties deserve. The fact that they're working together toward that cause is what Sting was singing about on "Synchronicity." Or is that serendipity? Or synergy? Just watch the trailer after the jump and laugh.
101 Hot Slave Princess Leia Photos (Manofest) You will respect Miley Cyrus as an actress, dammit (Pajiba)Exotic Cars At Redmond Town Center (CarDomain)Diora Baird Is A Hot Slave Girl (FilmDrunk)Sindi Bertheron's Spank Bank (GorillaMask)Man Drunk Drives On Barstool (IAmBored)7 Badass Cartoon Villains Who Lost To Retarded Heroes (Cracked)New Terminator: Salvation Pics! (Filmofilia)Eve Is Such A Tease (DreadCentral)The Worst Homemade Star Wars Costumes (Holytaco)Playboy Decorates For Virginia Girls (BustedCoverage)Sexy Natalia Solloum Gallery (Uncoached)If Pac-Man Obeyed The Laws Of Physics (Unreality)Groundhog Day – A Musical? (ThePlaylist)
MUTANT CHRONICLES starring Thomas Jane, Ron Perlman and MALKOVICH (!!!) is now available on HDNet Ultra VOD and opens in theaters on Friday, April 24. To celebrate, Magnet Releasing and Pressman Films is offering the Ultimate Mutant Chronicles Prize Giveaway! One lucky grand prize winner will receive: – An invitation (plus guest) to the LA premiere and after-party (transportation/hotel/expenses not included) – Autographed MUTANT CHRONICLES poster – MUTANT CHRONICLES Miniature Game Starter Set – MUTANT CHRONICLES Personalized Collectible Dog Tag – Your name to appear within end card on the MUTANT CHRONICLES DVD as a grand prize (subject to manufacturing schedule) 25 additional winners will receive: – Official MUTANT CHRONICLES Poster – MUTANT CHRONICLES Miniature – MUTANT CHRONICLES Personalized Collectible Dog Tag – Your name to appear within end card on the MUTANT CHRONICLES DVD (subject to manufacturing schedule) See how to enter – and some other MC goodies – after the jump!
Yesterday evening, Wired posted some pretty Trek-tacular recreations of famous Stark Trek scenes. The artist? Frank Elchesen. The medium? Legos. I'd really like to see the Tribbles episode done up, and I challenge Mr. Elchesen to somehow recreate the furry and adorable, yet pesky little buggers with Legos. I say it can't be done. Prove me wrong, Elchesen and I have a Star Trek T-Shirt for you!!!See more of his photos after the jump!
The new poster for Sam Raimi's Drag Me to Hell has been unleashed from the depths (and ShockTilYouDrop.com). Click to enlarge poster, and if you haven't seen the trailer, check it out here.
Kurtzman, Orci & Lindelof signed onto Trek Sequel (AICN)Apatow Slasher Gets Name (CHUD)Miramax Gets Into Sperm Donations (Variety)Paul Bettany will be a Priest (ComingSoon)Marvel Superheroes What the @%&? Series Takes Flight (MTV)
Bauer's been exposed. The CDC all dressed in their HAZMAT suits take Bauer, and tell him to get undressed. The scarred and naked Bauer gets sprayed down and scrubbed by the team while they take some tests.Meanwhile, Almeida and the bioweapon are dropped in StarkWood via helicopter. Jonas tells his bioweapon specialist to hurry up on getting the darn thing activated, 'cause the Feds "are going to be coming with all they got." He then walks inside where Almeida is getting interrogated. He asks him about what the FBI knows about the weapon. Almeida stays strong. Then his top aide tells him that they should probably dispose of the weapon before the Govvies come in and expose them for everything they got. "I think you're just trying to save your ass!" Jonas says.The CDC tells Bauer that he has an airborne virus, and he orders them to deliver him as evidence to FBI.
5. BATMAN'S TUMBLERMake/Model: Wayne Enterprises Tumbler (Military Grade)In Batman Begins, the Tumbler goes from the back room of Wayne Tech to the streets of Gotham in a matter of scenes, and the only way to describe Batman's badass ride is in the words of the startled Gotham beat cop: "a tank." It's got everything a costumed vigilante would need, including armor plating, boosters and rocket launchers. And in The Dark Knight, it's even got a built in escape vehicle called "The Batpod." You don't get that in your standard Toyota. When Michael Caine says, "The Lamborghini is much more subtle," he actually means it. 4. THE ECTOMOBILE (ECTO-1)
10. THE DEATH MOBILEMake/Model: 1964 Lincoln ContinentalFlounder's brother's car is wrecked when Otter, Boon and some of the other Animal House Brothers take it on an ill-planned road trip. But the enterprising D-Day resurrects it like a fiery phoenix and redubs it, "the Death Mobile." Face it, Flounder. This car is much better off as a nihilistic parade float then it ever was as a chick magnet. 9. THE GENERAL LEE
15. THE MIRTH MOBILEMake/Model: 1976 AMC PacerAhh… the Mirth Mobile from Wayne's World. Never before has such a pedestrian car been given a custom flame paintjob and a tape deck, and been transported into a chariot of the rock gods. You have not heard Queen's "Bohemian Rhapsody" until it has marched forth from the Pacer's speakers and crushed your eardrums. It will be mine… oh yes… it will be mine. (It would also be stretched into a limo version in Wayne's World 2.) 14. CAMERON'S DAD'S FERRARI
20. BUMBLEBEEMake/Model: 1977 & 2009 Chevy CamaroTransformers Director Michael Bay was accused of "raping our childhoods" when he eschewed Bumblebee's VW Beetle roots for the Camaro, but in the end, it was a stylistic choice that worked. Hell, it got Shia Laboeuf to first base with Megan Fox. Now that's a car worth the sticker price! (If you're into indirectly paying for sex, but aren't we doing that every time we take a date to Chili's and order an extra appetizer?) 19. DOMINIC TORETTO'S CHARGER
25. THE PUSSY WAGONMake/Model: 1997 Chevrolet C-2500 Silverado FleetsideKill Bill Vol. 1's Buck (Michael Bowen) is one lecherous scum sucker, and his nickname for his ride – painted brazenly all over the body – is certainly fitting. It's Buck's disregard for decency and driver's etiquette that puts this truck on the list. I wonder if it's ever run into the Wiener Mobile? 24. COBRA'S MERCURYMake/Model: Customized 1950 Mercury MontereyCrime is the disease. Meet the car that delivers the cure. Marion "Cobra" Cobretti (Sylvester Stallone) puts this tank of a car through war, destroying the Monterey while he demolishes a psychotic gang bent on world domination… This car is best driven with a match hanging out of the driver's mouth. 23. LOUISE'S THUNDERBIRD
30. POLICE SPINNERMake/Model: Mead VTOL aerodyneBlade Runner's celebrated production designer, Syd Mead, came up with the concept of the spinner, a flying car with vertical take-off and landing capabilities. Designer Mead has described the spinner as an aerodyne – a vehicle which directs air downward to create lift, though press kits for the film stated that the spinner was propelled by three engines: "conventional internal combustion, jet and anti-gravity". We recommend test driving one as long as you bring your Vangelis tunes to pump over the stereo. 29. MARCIE'S LAMBORGHINI
35. WALT'S GRAN TORINOMake/Model: 1972 Ford Gran Torino The car isn't actually driven all that much in Eastwood's Gran Torino, but it's the impetus for one of 2008's best offerings when Walt Kowalski's Gran Torino becomes the prize in an initiation for a neighborhood gang made up of Hmong kids. The car is a tough old relic, whose engine growls sound a lot like Eastwood's character every time he opens his mouth. The car spits out a lot fewer racial epithets, though. 34. FREDDY'S CADILLAC
In honor of Fast & Furious, opening this Friday, Screen Junkies wanted to take a joy ride down memory lane and pay homage to what we think are the most memorable automobiles ever put on film. To make this list, you didn't have to be the fastest; you didn't have to be the coolest. Hell, you didn't always have to work. But personality gets the most mileage, and these forty vehicles have enough personality to drive forever. Screen Junkies presents… The Top 40 Cars From Feature Films! 40. THE VW TRANSPORTER
According to MTV's Movie Blog, David Cronenberg is looking to do a sequel to 2007's Eastern Promises. In the original, Viggo Mortensen played a Russian gangster who was actually a spy for British Intel, and, as much as some may try to forget, many will vividly recall the now-famous scene in which Viggo's character teamed up with his exposed genitalia to battle a would-be assassin in a sauna. No reports as to whether or not the pair will link up again in the sequel, but speculation has begun… and Screen Junkies has the exclusive comic book adaptation of the speculation. Click to enlarge.
Actor Andy Hallett passes (IGN)ABC's "Ugly Yeti" (Take180) The World's Oldest Stoner (FilmDrunk)Brooke Burke has still got it (Manofest)Wolverine vs. The Comedian (Pajiba)Spank Bank: Natasha Q (Gorilla Mask)Baby Owl Tries To Swallow Rat (I Am Bored)Strangest Sex Objects (Cracked)Scorsese's Shutter Island Teaser (Filmofilia) XXXombies hits the Big Screen? (Dread Central)Win a Date With Tyler (Holy Taco)Nightcapper: Jon Daly needs a Hooters Waitress (Busted Coverage)When Children's Drawings go wrong (Uncoached)The Final Countdoooooown! (UnrealityMag)Terry Gilliam's Imaginarium of Dr. Parnassus update! (The Playlist)Foot Cobbler (Tom Oatmeal)City of God Ain't Got Sh*t on this (Nothing Toxic)Babes of the Ages! (Chickipedia)
According to Entertainment Weekly's Hollywood Insider, "Emily Browning (The Uninvited) will replace Amanda Seyfried in Zack Snyder's Sucker Punch for Warner Bros. You may remember Emily as "Violet" in 2004's Lemony Snicket's A Series of Unfortunate Events. She'll be playing "Baby Doll," an "insane asylum inmate who loses herself in a fantasy world where she dreams about escaping with her fellow inmates."
WIN A SET OF SIGNED LOBBY CARDS FROM THE FILM!This Friday, Roadside Attractions' Alien Trespass opens. It stars Eric McCormack, Jenni Baird and Robert Lauria*, and is a loving homage to classic sci-fi filmmaking. Screen Junkies and Roadside Attractions are extending the love to you by GIVING AWAY TWO SETS OF ALIEN TRESPASS LOBBY CARDS. Each set comes with 8 cards. One of the sets is signed by Eric McCormack, Jenni Baird, Dan Lauria and director R.W. Goodwin!
Today, X-Men Films posted eight high-res images from Fox's upcoming X-Men Origins: Wolverine, opening May 1st. I'm just going to shut up and let you look at the pretty pictures. See all of the others after the jump.
Another week gone by, another meth addled story of lies and close scrapes for our two favorite kingpins. "Hey Captain America", says a bum to Jesse as he is walking into a convenience store to meet up with Walt. Walt and Jesse decide they are going to have to put cooking on hold for a little bit while Walt's family gets less suspicious. So Walt tries to be sweet and get on Skyler's good side. He cooks them breakfast but Skyler is skeptical, as usual. Next, Walter reps Boz Skaggs as one of the best musicians of all time, maybe he's been getting high on his own supply. While cleaning up, Walt attempts to cover up the his second cell phone. Skyler, though, is unimpressed and storms out to Walt's dismay. Meanwhile Jesse's parents have wised up to his drug trafficking ways. So they decide to evict him from his house which they have the property rights to. Jesse's got 72 hours to get out.
Well, chaiwallahs, the submissions have been collected and the judges have spoken. The winner of Slumdog Millionaire on DVD or Blu-Ray is the user known as Novakane, whose comment, "The Corn? I ate it. Why?" tickled enough people's funny bones to take the prize.
Panthers are going to State in '08! What a magical week it was in Dillon, Texas, for fans of the Blue and Yellow. Emotions ran high because of twists around every bend. Grandma Saracen took a spill out of her car as she was backing out of the driveway and it became clear no amount of personal supervision would protect her from herself. The Garrity family finally broke down after hanging by a thread for so long, and it may or may not recover. That wasn't the only thing on Buddy's plate, as the boosters had to contend with a redistricting plan that might dismantle the powerhouse football team in the name of a better education for the children. Landry and the Collettes finally made amends, and it seemed as though the seeds for a Landry-Tyra reunion tour were planted. JD and his father, Joe, went through their growing pains, as JD came into his own and started making decisions for himself. This week was a return to form for Friday Night Lights as a TV show and for the Panthers as a football team, as they survived to fight another day.
With the deaths of loved ones behind them, the Connor crew split up. Sarah and John take refuge with an old friend, while Derek and Cameron take a moment away from each other's throats and point their guns in the same direction. Del Monte Sarah packs some bags and thinks back to when John was a child. His favorite stories were his mother's jungle stories, particularly the tale of El Viejo Del Monte: Old Man of the Forest. Del Monte was a hunter condemned to the jungle for all eternity. As his story goes he would kill every animal he encountered but not to feed on their meat, or warm himself with their furs. Instead, he would leave his prey to rot. His lust for blood was his mark, and each carcass he left behind was a lesson to those who crosses it explaining what God had turned Del Monte into: half man, half animal. Some considered him a protector for he preyed upon predators. It was his curse to be vigilant forever.


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Alumni Messenger
An Update From Saybrook Alumna Marie Fonrose in Haiti03/09/2010
Update from Marie in Haiti.
God is Good, all the time!
This past Friday I was a guest on the Pignon's radio station (102.5) discussing the earthquake's psychological impact on the people, especially children. Many cities listen to this station and we received many calls from across the city and Port-au-Prince about the issues that people face post the earthquake. We ran out of time and we were not able to take every caller. This week Pastor Mioche Rock and I will do another session to give people a chance to process and to answer their questions.
Today, I spent the first half of the day at a school (K-12) visiting
classes and educating people on what to expect and how to help others
move on. We talked with the teachers and administrators on various
symptoms they may see in the classroom from the earthquake victims.
Tomorrow morning I will go back to the school to meet with a group of
adults from Port-au-Prince to get a sense of where they are since
January 12 and to answer their questions on mental health. This
afternoon will be spent in the hospital with patients and we (Pastor
Rock and I) will do some community visits as well.
I attended Pastor Rock's church yesterday for worship. I was impressed with the youths there. Since the earthquake they have been
volunteering their time to cook a hot lunch for the patients in the
hospital so I commended them for this effort. In hospitals in Haiti,
the family is responsible for cooking and bringing the food to the
patient. We know that a lot of people are in this town without their
family so the youths are providing a great service. What won my heart
with them was the small donation I made to the group; they were so
grateful, one would have thought I gave them a $1000. Everywhere you
turn, there is a prayer meeting going on despite their suffering. Keep us in your thoughts!
Until then,
Alumnus Michael Mayer, PhD '77 Presents on "Ask the Experts"03/09/2010
Saybrook Alumnus Michael Mayer, PhD '77 co-presents with Maggie Phillips as part of her "Ask the Experts" teleseminar series on Wednesday, March 17, from 9 am – 10:30 AM Pacific time. The topic is Qigong and Bodymind Healing: An Integrated Approach for Stress and Pain.
Maggie has written a recent book called Reversing Chronic Pain, which features a multi-modal approach to reversing the effects of persistent pain. She also has created a multi-media, online self-treatment program at www.reversingchronicpain.com and has released a pain CD program through www.hypnosisnetwork.com. To learn more about Maggie, please go to www.maggiephillipsphd.com, where you will discover how she uses a combination of breathing, mindfulness, hypnosis, Somatic Experiencing and Energy Psychology to help clients obtain rapid, lasting results.
Dr. Mayer will be contributing information from his last two books, Energy Psychology: Self-Healing Practices for Bodymind Health and Bodymind Healing Psychotherapy: Ancient Pathways to Modern Health.
Michael's specialty is in self-healing methods derived from Western psychology, energy psychology, qigong, tai chi and other ancient healing practices. For more information on this teleseminar, please see his website: www.bodymindhealing.com/Teleseminars.
Please register now at: www.maggiephillipsphd.com/courses_teleseminars_mm.html. The teleseminar package includes:
• Access to this event by telephone or internet connection
• A one hour, intensive presentation followed by 30 minutes of live questions and answers
• Unlimited 30 day replay whether you attend live or not so you don't miss a moment if you have a schedule conflict
• A study guide to help you organize your learning
Michael Mayer, Ph.D. Saybrook '77
Director- The Bodymind Healing Center
2029 Durant Ave - Suite 202
Berkeley, Ca 94704
Saybrook Alumni and Faculty Present at the First East-West (International) Existential Psychology Conference in Nanjing03/09/2010
Several Saybrook Community Members will be presenting at the First East-West (International) Existential Psychology Conference in Nanjing, including: Dr. Kirk Schneider, Saybrook Alumnus and Faculty Member (delivering the opening keynote); Dr. Susan Gordon, Saybrook Alumna; Dr. Ed Mendelowitz, Saybrook Faculty; and former Saybrook instructor, Dr. Ilene Serlin. See also the Beijing workshop where Dr. Schneider will be presenting on existential psychology and on his book with Rollo May, Psychology of Existence.
or go to:
The Chair of the Board of Trustees Announces Appointment of Saybrook University's New President03/09/2010
Dear Saybrook Community,
I am delighted to announce that the Board of Trustees has unanimously approved the appointment of Mark Schulman, PhD, as President of Saybrook University.
Mark, who will begin his term July 1, 2010, has a distinguished career and an outstanding record of accomplishment in higher education. The Board chose him from a number of excellent candidates because of his unique qualifications to lead Saybrook in fulfilling its mission as a humanistic university serving the needs of today's world.
Mark currently serves as President of Goddard College (Vermont and Washington) and has held this position since 2003. Under Mark's leadership Goddard flourished as a low residency educational model dedicated to "progressive education for creative minds." While supporting and nourishing Goddard's core values Mark tripled the endowment, substantially increased enrollment, significantly strengthened the school's financial position, and raised its national stature and reputation.
Prior to joining Goddard, Mark served in a variety of academic leadership positions that included: President and Professor of Humanities at Antioch University Southern California; and Academic Vice President, Dean of the College, and Associate Professor at Pacific Oaks College (California and Washington). He has held faculty positions at the New School for Social Research (New York), City College of New York, Saint Mary's College of California, and others.
Mark received his PhD in Communications from the Union Institute and has consulted and published extensively on higher education and communications strategies and issues. Prior to his July 1, start date, he will also join us at the June Residential Conference, Alumni Homecoming, and commencement for the Graduate College of Psychology and Humanistic Studies.
Mark, Bob Schmitt, our interim president, and the Board will work together to ensure that the present momentum of growth and development continues without interruption or shift in direction.
Mark asked that I share the following statement from him with all of you.
I am delighted to be joining Saybrook at this important and exciting moment in its history. Saybrook and I share an ethos and values that will make it a great time for the institution in all its constituencies – faculty, staff, students, Board, alumni, and friends – to continue our momentum as a leader in education that profoundly changes all of us and changes the world.
Please join me in welcoming Mark to Saybrook.
Alison Shapiro
Chair of the Board of Trustees
Saybrook Alumna and Board of Trustees Member Renee Levi, PhD '03 Co-Directs Power of Place Initiative03/05/2010
Leadership Development at The Banff Centre, along with The Fetzer Institute's Powers of Place Initiative, would like to invite you to participate in an intimate forum on Place-Based Leadership, which will explore the role of place in transformative leadership theory and practice.
The forum will be held at The Banff Centre in Banff, Alberta, Canada from May 9 -12, 2010.
The forum, Place-Based Leadership, will be an opportunity to come together to explore how our surroundings – place, space, and environment – can work with us as leaders to inspire and revitalize our organizations and communities. Although much has been discovered and shared about transformational leadership practice, place – the container in which we bring people together to do their work – has been largely overlooked. By connecting people like you in study, and in dialogue, enriched through an intimate experience of place, in glorious Banff and the Bow River Valley, we intend to deepen our understanding of leadership and collective wisdom by including the more invisible dimensions that contribute to transformation.
Our intention is that what we learn together during this May, 2010 forum, will be the basis for future programs and curricula that can help us as human beings reestablish our profound relationship with place for the benefit and future of both.
Faculty and staff from Leadership Development at The Banff Centre will join with Renee Levi and Michael Jones, of the Powers of Place Initiative, to seed the dialogue with new ideas and practices, and to facilitate the two and one half days we will have together. We will begin at dinner on Sunday, May 9th and end after breakfast on Wednesday, May 12th. As The Banff Centre is located in Canada, the fee for the retreat is $1500 CAD (approximately $1428 USD), and includes three nights' accommodation at The Banff Centre, meals and instructional materials.
We hope you can join us for this unique experience. Please respond to Katrina Donald at The Banff Centre, firstname.lastname@example.com, to register for the forum. If you have questions or need additional information, please contact:
Michael Jones email@example.com
Renee Levi email@example.com
Sheryl Erickson firstname.lastname@example.com
You can visit our websites for more information about the sponsoring organizations, www.powersofplace.com and www.banffcentre.ca.
Alumnus David Whitsitt, PhD '08 and Three Saybrook Doctoral Students Present at The International Human Science Research Conference in August03/05/2010
Alumnus David Whitsitt, PhD '08 and Three Saybrook Doctoral Students Erica Shane Hamilton, Miyuki Tomura, and Christine Thomas Present the Symposium
Giving Voice to Experience: Health and Sigma, Student Contributions to Qualitative Research
The International Human Science Research Conference
Seattle University
August 4-8, 2010
Abstract: This symposium will showcase the power of qualitative research to express the human experience of living with illness or stigma, as well as the experience of the treatment process. The symposium includes four students/recent graduates of Saybrook University, and the research ranges in method from phenomenology, to grounded theory, to mixed methods.
The first presentation applies grounded theory and mixed methods to understand the psychosocial and existential stresses in the lives of women with CPP as well as some of their coping mechanisms. The researcher combined qualitative interviews with innovative web-based daily tracking strategies to sample the daily experiences of pain and life stress of the participants.
The second presentation used a phenomenological methodology to explore the lived experiences of three couples, where one of the partners has undergone coronary artery bypass graft surgery (CABG). The study highlighted the impact of meanings or beliefs, coping styles, and marital quality on the couples' experiences of bypass surgery.
The third presentation is a descriptive phenomenological study of a prostitute's lived experience of stigma. The researcher used a semi-structured interview method and Smith and Osborn's (2003) interpretive phenomenological analysis, to disclose ten central themes in the initial prostitute's experience. Additional interviews are now in progress with five additional prostitutes to delineate common themes across subjects.
The fourth paper is a mixed method study exploring the experience of living with Irritable Bowel Syndrome and the experience of undergoing an alternative therapy for the disorder. The researcher will use a case study approach integrating qualitative interview data with presentation of psychophysiological changes in treatment.
Each of the presenters will provide a rationale for choosing the specific methodological approach, and will highlight strengths of this qualitative method or mixed methods approach for the problem under investigation.
Moderator: Donald Moss, PhD, Chair, College of Mind-Body Medicine, Saybrook University
Presenter 1: Erica Shane Hamilton, doctoral candidate
Title: Interview Combined with Daily Tracking Questionnaires: Gaining Insight into the Stresses and Coping Efforts of Women with Chronic Pelvic Pain
Presenter 2: David Whitsitt, PhD
Title: Coronary Artery Bypass Surgery: The Experiences of Three Couples
Presenter 3: Miyuki Tomura, doctoral candidate
Title: A Prostitute's Lived Experience of Stigma
Presenter 4: Christine Thomas, doctoral candidate
Title: Heart Rate Variability Training for Women with Irritable Bowel Syndrome: Case Study Research
Discussant: Steen Halling, PhD, Professor of Psychology, Seattle University
Saybrook Alumni Haiti Fund Raises More Than $150003/01/2010
Saybrook Alumni Haiti Fund Raises More Than $1500 in Support of Alumna Marie Fonrose's Mission
On February 19th Marie left for Haiti. In little over a week she has begun her work as a psychologist at a hospital in Pignon; has visited an orphanage and held group therapy; has been on the radio with local clergy educating the public about mental health issues in Haiti; and has visited an elementary school to speak with teachers and administrators!
See several Alumni Message Board entries below to hear from Marie in her own words.
Ransom Center Awards Annual Fellowships02/26/2010
The Ransom Center annually awards 50 fellowships to support scholarly research projects in all areas of the humanities, including literature, photography, film, art, the performing arts, music, and cultural history. Applicants must demonstrate the necessity of substantial on-site use of the Center's collections. The fellowships range from one to three months, with stipends of $3,000 per month. Also available are $1,200 to $1,700 travel stipends and dissertation fellowships with a $1,500 stipend. The stipends are funded by individual donors and organizations, including the Ransom Center, the Andrew W. Mellon Foundation, the Hobby Family Foundation, the Dorot Foundation, the Schusterman Center for Jewish Studies at The University of Texas at Austin, the American Society for Eighteenth-Century Studies, the South Central Modern Language Association, and The University of Texas at Austin Office of Graduate Studies. http://www.hrc.utexas.edu/research/fellowships/
A Message from Alison Bonds Shapiro, Chair of Saybrook's Board of Trustees02/26/2010
Dear Students, Faculty, Alumni, and Staff,
During this transition period, I promised to periodically update you on the progress we are making at Saybrook University on the presidential search. By design the presidential search process has been discreet. However, there are a few items I would like to share with you and to give you an idea of where we are in the process.
First, the Search Committee was overwhelmed by the number of resumes received for this position. There is a lot of interest in and enthusiasm for Saybrook University at this moment. This response has to do with the investment of hard work and resources the staff and Board have put into our transformation into Saybrook University. It took the Search Committee and the search firm a good deal of time to review these candidates' applications and select a list with whom we conducted extensive face-to-face meetings. After doing so, the Search Committee came to agreement on a short list of candidates, all of whom have the credentials, experience and passion to lead Saybrook University. We were very impressed with the caliber of candidates who stepped forward in this search.
Once this final group of candidates was identified, which took place before the holiday break, the Search Committee turned the process over to the Board of Trustees. We were pleased to find ourselves in such an optimal position to make a choice for the future leader of Saybrook University. The Board of Trustees fully realizes the potential of this moment in Saybrook's history and is conducting the selection of our next President with the appropriate care and thoughtfulness. We have been meeting with the final candidates and conducting thorough background and reference checks to ensure our decision is as informed as possible. We have been exhaustive in our due diligence, and we are impressed by what we are learning about our choices.
The carefulness with which we are conducting this search takes a good deal of time. However, we are confident it will pay off in as we ensure the Saybrook University community that we have made the best decision possible. As soon as there is more information to report to you, I will be happy to do so. In the meantime, thank you for all the good work you have been doing to keep Saybrook moving forward during this transition, and thank you to the alumni for your ongoing support.
Saybrook Alumna Deirdre Bundy, PhD '09 Opens Mentoring Service for Adolescent and Teenage Girls02/26/2010
Saybrook Alumna Deirdre Bundy, PhD '09 and Briana Schuck are very excited to announce the official launching of the LITTLE LADIES SPORTS CLUB, a mentoring service for adolescent and teenage girls ages 8-18 years of age in the Malibu, Venice, Santa Monica, Pacific Palisades, Marina del Rey, Playa del Rey, Westwood, Brentwood, Bel Air and Beverly Hills, CA area! After months of creation and collaboration we are now enrolling young ladies for activity based mentoring!
And here is what's in it for you! We are pleased to offer REFERRAL REWARDS! It's easy – if you have a friend, family member etc. with a daughter and they sign up to work with us you will receive a $25 gift card!
Sounds simple enough? Just send them (or print out) the flyer attached to this email and make sure they mention your name when they sign up!
The LITTLE LADIES SPORTS CLUB is a mentoring service for adolescent and teenage girls ages 8-18 years of age. We pair strong, athletic, and healthy female role models with young girls experiencing various challenges in their lives. This relationship allows the girls to work through such issues as low self-esteem, body image issues, low sociability, low self-confidence, sedentary lifestyle and substance abuse just to name a few. The outcome is an empowered sense of self, a new enjoyment of physical activities and a healthy body!
For more information please visit our website: http://www.littleladiessportsclub.com
Also, become a fan on facebook!
Thank you so much for all of your love, support, and assistance in helping us and these girls!
Briana and Deirdre
email@example.com email@example.com
310-402-6479 310-804-2402


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It must have been 27 years ago that I had my first experience with so-called "alternative medicine." I was 13 and had been suffering chronic daily headaches and mid-back pain for half-a-dozen years. I was already seeing Philadelphia's best mainstream medical professionals, taking a plethora of prescription meds, being put through dozens of tests, scans, protocols…. to no avail.
My father (who is an osteopath) then took me to see a chiropractor, and do you know what happened? Within minutes my back and neck felt so much looser! My restricted movement was returned within normal ranges. And I also started taking natural supplements. Over all, it was an amazing feeling…
I went back several times that week for adjustments and, at home, attempted the exercises I was instructed to do. But the pain, and my suffering, returned and continued on. This is not surprising. In fact, it is a common occurrence when people try alternative therapies.
Why This Happens
The problem is that many people turn to alternative therapies as a last resort. They have had little success with mainstream medicine, have become desperate and now are expecting a miracle cure or at least a fast turnaround of their signs and symptoms.
While I served as director of the Integrated Energy Medicine healing center in Philadelphia, I did thousands of examinations, consultations and treatments using alternative therapies and herbal medicines. I would have been delighted to offer patients both a miracle cure and fast results… if such were possible. And many times I was successful in "curing" someone in short order. But with other cases, the sheer depth, difficulty and timeline of the problem made that task impossible.
Let me explain why some patients experience great success while others simply have little to no change in their signs and symptoms and find alternative therapies to be a waste of time.
A Different Model
In general there is a vast philosophical and procedural difference in the approaches of mainstream medicine and alternative therapies. Mainstream bio-medicine uses a disease-based model of health. That is, patients see their primary care physician when they are ill, the doctor diagnoses the illness (disease) and then prescribes a protocol of curing that disease. Often there is no cure… but pain and other signs and symptoms are "managed" by prescription medication and/or surgery.
Alternative therapies, on the other hand, work from a wellness model. That is, the focus is on returning the body to homeostasis (balance) and maintaining that balance to ensure good health and long life. They proactively accomplish this through diet, exercise, mind/body techniques, herbs and supplements, massage and so on. All are methods of alleviating pain, illness and disease by restoring balance to the body. If you have back pain and take a supplement, the pain will probably remain… for a while. But if you follow a protocol of regular supplementation with safe stretches and perhaps acupuncture or chiropractic care… the body will rebalance and the issues will resolve. But this takes time.
Generally speaking, many alternative therapies aim at rebalancing the body to restore health. Chinese medicine uses herbs to balance blood, energy, body fluids and organ function. Acupuncture uses needles to open meridian lines and correct energy imbalances. Chiropractic uses manual adjustments to realign the spine to allow correct functioning of the nervous system.
Don't Try… Do!
So why does the title of this article claim that alternative therapies are a waste of time? Well, actually, they are not. But the "trying" of alternative therapies most certainly IS. You see, there is a difference between "trying" and "doing." Trying means "you didn't do" something. Let's examine some common statements I've heard in my practice, and what they really mean.
Statement: I tried to call you and cancel my appointment. Translation: I did not call you.
Statement: I tried acupuncture, but it didn't help. Translation: After a few visits I was not cured and so decided not to continue and follow the protocol to the end.
Statement: I've been really trying to eat right and do my exercises. Translation: I eat right once in a while, and I exercise when I remember to do it.
Trying means not doing. And if you are not fully engaged in the doing of alternative therapies… seeing them through to the end… following the protocol… doing what you have been instructed to do… then they will not "work." Not because they failed you, but because YOU failed you.
You see, the therapies themselves are not the problem (unless you have chosen to follow the wrong therapy for your health issue). They are also not time-consuming. Rather, it is the body that takes time "to allow" the method to take hold and effect change and reestablish balance. But this takes time because the body likes to stay where it is, as it requires little effort to do so. After repeated treatments, or a period of time spent doing exercises or taking herbal supplements, the body finally realizes that it is actually easier to be in a state of homeostasis (balance) than to exist in a state of imbalance. It then "lets go" of its old unhealthy holding pattern. Now it can fully embrace a healthy pattern, and positive change can take effect.
Think of it like working out at the gym. If you are out of shape and lift weights you will be sore. But little by little you will be less sore after the exercise. If you only lift weights once in a while, your muscle size, shape and density will not visibly change. But if you stick with it ("do" it), you will notice your body changing in positive ways.
Internally this is what is happening with alternative treatments. Each day, each treatment, each bottle of supplements, each breathing exercise and dietary change brings you one day closer to the body allowing them to take hold and the body stepping out of its own way to effect a cure.
They're No Last Resort
The worst part is, people still look to alternative therapies as a last resort, and mainstream pharma drugs and surgery as a first choice. This is perverse. Using the big guns for the beginning of a problem (depending on severity) is ridiculous. My feeling on maintaining a balance between mainstream and alternative medicine is this: Everyone needs to get a physical each year, including blood and urine tests. If a problem is found they should seek alternative, non-toxic, non-invasive methods to balance the body. After a period of time they should have more tests run to see if the problem is better or worse. If better, continue with alternative medicine. If worse, and in the red zone of health, then turn to mainstream medicine for help. Not the other way around.
As it stands, alternative practitioners tend to get chronic cases, and after years or decades of toxic drugs and surgeries have truly damaged their patients' body. And they are left to balance these bodies, in short time, at low costs and with high hopes.
It's time people reframe their minds on this issue. So the next time you feel un-well, seek out alternative therapies first. But you must DO it and not simply TRY it. It takes time, effort, discipline, but in the end being balanced means being healthy.
And taking personal responsibility to do what needs doing—and not depending on a doctor to do it for you—is the greatest gift you could ever give to yourself.
—Dr. Mark Wiley


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Cool, then refrigerate any leftover cooked meat. Use to make sandwiches the next day.
A perfect flavor complement to the tender pot roast, the colorful carrots are an excellent source of vitamin A.
* Nutrition information is estimated based on the ingredients and cooking instructions as described in each recipe and is intended to be used for informational purposes only. Please note that nutrition details may vary based on methods of preparation, origin and freshness of ingredients used.
YUCK! It didn't look like a very good recipe, but I had all the ingredients, so I gave it a try. Threw it out and made grilled cheese sandwiches that night.
BTW, who is "the cook"? I've never seen so many wildly contrasting reviews on every recipe! I've counted as many 7-8 reviews on one recipe, rating "loved it", "hated it" and everything in between!
I made this recipe and I thought it was good because the A1 changed the flavor and made it very different.
Tasted ok. I needed to add more seasoning to it at the end, since it was not very flavorful. I used 2 tablespoon of A1 instead of a 1/2 cup as suggested. I would probably not try this recipe again. There's got to be something better out there to try.


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Accessory Report: The Most Comfortable Shoe Trend Of The Season
- 1 of 25
These days, it seems you can't throw a pebble in the street without hitting a slip-on sneaker or two, and luckily our favorite street style stars are providing outstanding outfit examples of how to wear this surprisingly chic shoe trend. Click through for nine easy-to-try ensembles, and shop our favorite slip-on sneakers at the end!
- 2 of 25
Street Style
Style Tip: Brighten up black sneakers with white denim and an easy scarf.
Image via Stockholm Street Style
- 3 of 25
Street Style
Style Tip: If you're wearing head-to-toe black, try slip-on sneakers in a holographic texture.
Image via Stockholm Street Style
- 4 of 25
Charlotte of Arty Filles
Style Tip: Pair your animal print slip-ons with cuffed jeans and a camel coat.
On Charlotte: Sandro sneakers
- 5 of 25
Street Style
Style Tip: If your sneakers are in a jewel-tone hue, style them with a white dress for an appealing contrast.
- 6 of 25
Tamu McPherson of All The Pretty Birds
Style Tip: Ditch your sporty separates and try a fashion-forward frock with your slip-ons.
- 7 of 25
Camille Charrière of Camille Over The Rainbow
Style Tip: Your plaid sneakers will look cozy with a chunky-knit turtleneck.
On Charrière: Club Monaco coat, sweater, and pants; Celine sneakers.
- 8 of 25
Zina Charkoplia of Fashion Vibe
Style Tip: Give your sneaker look some sex appeal with a silky camisole and sleek blazer.
On Charkoplia: Zara blazer, top, and sneakers; Bershka jeans.
- 9 of 25
Iris Gravemaker of Fashion Zen
Style Tip: Try your sneakers with a statement sweatshirt.
On Gravemaker: Acne sweatshirt; H&M pants; Celine sneakers.
- 10 of 25
Style Tip: Wear your sneakers with lace-up pants for an instant cool-girl ensemble.
On Mija: Cos hat; Sandro coat; Zara sweater; Isabel Marant x H&M pants; Celine sneakers.
- 11 of 25
Chiara Ferragni of The Blonde Salad
Style Tip: Go for a pair of flowy trousers to drape over your sneakers.
On Ferragni: Erika Cavallini sweater and pants; The Blonde Salad x Steve Madden sneakers.
- 12 of 25
- 13 of 25
Jungle Slip On Sneakers ($150)
We can totally see Cara Delevingne rocking these wild kicks.
- 14 of 25
Eugene Riconneaus
Wine Stacy Skate Shoes ($465)
The combination of burgundy and navy blue gives off a preppy vibe.
- 15 of 25
Bicolor Metallic Leather Slip-On Sneakers ($650)
There's simply no reason not to buy these, in our humble opinion.
- 16 of 25
H by Hudson
Annuk Slip On Sneakers ($215)
This pair are the perfect barbeque footwear choice.
- 17 of 25
Marc by Marc Jacobs
Slip-On Sneakers ($438)
The floral print on these sneakers is utterly unique.
- 18 of 25
Mother of Pearl + Jim Lambie
Printed Canvas Slip-On Sneakers ($370)
Stripes, florals, and sneakers? We've found the ultimate shoe, ladies and gentlemen.
- 19 of 25
Report Keelin Slip-On Sneakers ($48)
These slip-ons are subtle and statement-making, all at once.
- 20 of 25
Linea Rossa Floral-Printed Slip-On Sneakers ($490)
Get a jumpstart on spring's tropical trend with these hibiscous sneaks.
- 21 of 25
Saint Laurent
Metallic Leopard Slip-On Sneakers ($495)
Slip-on sneakers in an animal print is the ultimate no brainer.
- 22 of 25
Sam Edelman
Becker Haircalf Sneakers ($110)
The print may be undercover, but you'll stand out in these camo sneakers.
- 23 of 25
The Blonde Salad x Steve Madden
NYC Slip On Sneakers ($130)
Every woman should have a python print accessory, why not try these on for size?
- 24 of 25
Katch Slip On Trainers ($136)
We present: the sneakers that will go with everything.
- 25 of 25
Classic Slip-On Sneakers ($47)
A slip-on sneakers roundup wouldn't be complete without Vans' classic iteration.


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- 800.878.7323
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A Gate at the Stairsby Lorrie Moore
Staff Pick
Lorrie Moore has long been one of my favorite writers, and her first novel in years does not disappoint. With unique, full characters, an incredible level of emotional detail, and her trademark psychological wit, A Gate at the Stairs is a graceful, funny, powerful read.
"No one who is a fan of Lorrie Moore, or of coming-of-age novels rich in wit and specificity, should resist reading A Gate At The Stairs. It contains patented Moore delights: mordant humor in shades of gray to charcoal, a quirky, self-deprecating heroine who notices both too much and not enough about the people in her life, a bushel of laugh-out-loud depictions of contemporary American mores and fripperies, and finally, a double examination of the fragility of love's intent." Holloway McCandless, Identity Theory (read the entire Identity Theory review)
Synopses & Reviews
Publisher Comments:
In her best-selling story collection, Birds of America, Lorrie Moore wrote about the disconnect between men and women, about the precariousness of women on the edge, and about loneliness and loss.
Now, in her dazzling new novel — her first in more than a decade — Moore turns her eye on the anxiety and disconnection of post-9/11 America, on the insidiousness of racism, the blind-sidedness of war, and the recklessness thrust on others in the name of love.
As the United States begins gearing up for war in the Middle East, twenty-year-old Tassie Keltjin, the Midwestern daughter of a gentleman hill farmer — his Keltjin potatoes are justifiably famous — has come to a university town as a college student, her brain on fire with Chaucer, Sylvia Plath, Simone de Beauvoir.
Between semesters, she takes a job as a part-time nanny.
The family she works for seems both mysterious and glamorous to her, and although Tassie had once found children boring, she comes to care for, and to protect, their newly adopted little girl as her own.
As the year unfolds and she is drawn deeper into each of these lives, her own life back home becomes ever more alien to her: her parents are frailer; her brother, aimless and lost in high school, contemplates joining the military. Tassie finds herself becoming more and more the stranger she felt herself to be, and as life and love unravel dramatically, even shockingly, she is forever changed.
This long-awaited new novel by one of the most heralded writers of the past two decades is lyrical, funny, moving, and devastating; Lorrie Moore's most ambitious book to date — textured, beguiling, and wise.
"Moore may be the most irresistible contemporary American writer....On finishing A Gate at the Stairs, I turned to the reader nearest to me and made her swear to read it immediately." Jonathan Lethem, New York Times Book Review
"With dizzying wit and acute intelligence...A Gate at the Stairs features a Midwestern coed turned part-time nanny drawn into the full-time drama of a family who all demand babysitting." Vanity Fair
"The ending of this book is a miracle of lyric force, beautiful and beautifully constructed." Vince Passaro, O, The Oprah Magazine
"The unique vision and exquisite writing cast a spell." Booklist (starred)
About the Author
Lorrie Moore is the author of the story collections Birds of America, Like Life, and Self-Help and the novels Who Will Run the Frog Hospital? and Anagrams. Her work has won honors from the Lannan Foundation and the American Academy of Arts and Letters, as well as the Irish Times International Prize for Fiction, the Rea Award for the Short Story, and the PEN/Malamud Award. She is a professor of English at the University of Wisconsin in Madison.
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Elk velvet antler plus 250mg (average per serving) of pharmaceutical grade glucosamine sulfate.
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Loksak Multi Pack with aLoksak Bags
The Loksak Multi Pack with aLoksak Bags offer a durable, element-proof solution to keep your gadgets and other important valuables in good condition. These transparent bags are made of 100% Polyethylene film that's medical-grade and FDA-approved. It makes the bags flexible, resistant to punctures, and durable against stretching or pulling. Even if your smartphones, PDAs, GPS devices, and other items are submerged 200 ft. underwater, they will still be in good condition as long as they are stored in these bags. Don't worry about the water or other elements such as air, dust, and humidity entering the bags because their hermetic seal keeps them out. This multi pack set comes with aLoksak bags in 12 in. x 12 in., 13 in. x 11 in., and 16 in. x 24 in. sizes. Protect your items wherever you go. Store them inside the Loksak Multi Pack with aLoksak Bags.
This product has a limited warranty of 0 months for parts and 1 month for labor.
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Video: Geoffrey Mearns discusses Dimora verdict; Part 2
Video: DImora trial: Gabor's attorney leaves courthouse
Video: Dimora Arrives at Court - March 9th, 2012
Video: Geoffrey Mearns about the Trial; Part 1
Video: Dimora's wife, attorneys leave federal court
Video: Legal analysis: What's next in Dimora case
AKRON -- A jury has convicted former Cuyahoga County Commissioner Jimmy Dimora on 33 counts.
The judge revoked Dimora's $50,000 bond and ordered him detained. Marshals took Dimora from the court in handcuffs.
Verdict details
Dimora was accused of bribery and racketeering and pleaded not guilty. Dimora was on trial with a former county employee, Michael Gabor, who also has denied allegations of corrupt activity.
The jury convicted Gabor on seven of eight counts.
Sentencing is yet to be scheduled.
When asked by WKYC.com reporter Kim Wendel while in the elevator what he thought following the verdict, Gabor Attorney Lief Christman replied with one word, "Brutal."
He went on to say he was sorry the lawyers were barred from talking to the media at this time. The judge ordered the jury to return on Tuesday.
Expanded coverage: Dimora trial
WKYC's Eric Mansfield, who was waiting outside, reports that defense attorney Bill Whitaker stormed out of the courthouse, knocked into photographers and got inside a waiting car.
The trial in federal court in Akron included seven weeks of testimony. The case went to the jury March 2 after closing arguments.
A prosecutor recounted Dimora's alleged involvement in various schemes, referring to him as "king of the county." His defense team attacked the credibility of government witnesses, saying they testified to get reduced prison sentences in the corruption probe.


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Today is October 10, 2015
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April 18, 2013
Carbon County News
April 18, 2013
Carbon County News
No more Grand Staircases, Jones tells Congress
The specter of a Clinton-like designation of more lands as national monuments or protected areas has laid heavy over rural Utah since the late 1990s, when the former president created the Grand Staircase Escalante National Monument near Kanab....
Emotional meeting of ECC-Sunnyside councils on merger
The first official public hearing concerning a possible merger of East Carbon and Sunnyside cities drew a full house Tuesday night as Sunnyside residents were informed of their city's intention to place consolidation on the November ballot. ...
Stage is set for Helper's underground rebuilding; new utility rates adopted
The long-awaited, long-planned reconstruction of Helper's underground utility systems is slated to begin next Monday. Meanwhile, the city council has already adopted a new rate structure for water and sewer service to fund some $12 million in long-t...
T-shirts and tears
The art exhibit on display this week at USU Eastern's student center ballroom has an accessory not seen in other galleries: a box of tissues for visitors who need to wipe away tears....
Golf cart tour to raise money for wounded warriors will stop in Price
A drive to raise money for servicemen and women who have been wounded while in the military has taken a new turn.
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Rifampin and Efavirenz Interactions in Older Children
- Full Text View
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- Disclaimer
- How to Read a Study Record
Efavirenz is an essential component of HIV treatment in children aged 3 years or older on anti-tuberculosis (anti-TB) treatment. However, the appropriate efavirenz dose during anti-TB treatment remains unclear. Rifampin (an anti-TB drug) increases the activity of the drug metabolizing enzymes that breakdown efavirenz, which may lead to low blood levels of efavirenz and treatment failure during cotreatment. The drug-to-drug interactions between the HIV and anti-TB drugs also vary between individuals based on genetic factors. This study will investigate the effects of anti-TB treatment, as well as drug-gene interactions on the blood concentrations of efavirenz in children with HIV and TB infections. Such data could enhance optimization of efavirenz dosage or selection of alternate regimens in some children.
|Study Type:
|Study Design:
|Observational Model: Cohort
Time Perspective: Prospective
|Official Title:
|Effect of Rifampin-containing Anti-TB Treatment on Efavirenz Pharmacokinetics in HIV/TB Co-infected Children Aged 3 - 14 Years
- Area under time curve from time 0-24 hours(AUC0-24h) of efavirenz [ Time Frame: At week of 4 of HIV therapy ] [ Designated as safety issue: No ]Compare efavirenz AUC0-24h between HIV-infected children without TB and those with TB on rifampin-containing anti-TB therapy in co-infected patients
- Number of children with grade 3 or 4 liver enzymes elevations compared to baseline, new onset of skin rash, nausea, vomiting or treatment modification due to drug side effects [ Time Frame: up to week 24 of therapy ] [ Designated as safety issue: Yes ]Compare frequency of adverse events as a measure of safety and tolerability between HIV-infected children with and without TB coinfection
- Number of children with efavirenz 24-hour post-dose concentration (C24h) < 1000 ng/mL [ Time Frame: At week 4 of therapy ] [ Designated as safety issue: No ]Relationship between clinical factors (weight, gender, nutritional status) as well as genetic factors (CYP2B6 516G>T, as well as CYP3A4, ABCB1, CAR and PXR polymorphisms) and efavirenz AUC0-24h and efavirenz C24h will be investigated
- Number of children who discontinue efavirenz therapy due to drug side effects [ Time Frame: Up to week 24 of HIV therapy ] [ Designated as safety issue: Yes ]Relationship between clinical factors (weight, gender, nutritional status) as well as genetic factors (CYP2B6 polymorphisms) and treatment modification due to drug side effects in the combined study population
- Trough concentration (C24h) of efavirenz [ Time Frame: At week 4 of therapy ] [ Designated as safety issue: No ]Compare efavirenz C24h between HIV-infected children without TB and those with TB, as well as in the absence of and presence of rifampin-containing anti-TB therapy in co-infected patients
- AUC, Cmax and clearance of efavirenz on and off rifampin-containing anti-Tb therapy in HIV/TB co-infected patients [ Time Frame: at week 24 of therapy ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
EDTA plasma Whole blood DNA
|Estimated Enrollment:
|Study Start Date:
|October 2012
|Estimated Study Completion Date:
|May 2017
|Estimated Primary Completion Date:
|May 2017 (Final data collection date for primary outcome measure)
|Ages Eligible for Study:
|3 Years to 14 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
HIV-infected children with and with TB aged 3 to 14 years old
Inclusion Criteria:
- Children with active TB with or without HIV co-infection. Active TB diagnosis defined by clinical criteria consistent with active TB and/or a positive AFB smear or mycobacterial culture.
- Aged 3 months to 14 years old
- Are available for follow-up until completion of TB treatment and/or achievement of a study endpoint like discontinuation of therapy, and/or pharmacokinetic sampling.
Exclusion Criteria:
- Unable to obtain informed signed consent parent(s) or legal guardian
- Have AIDS-related opportunistic infections other than TB, history of or proven acute hepatitis within 30 days of study entry, persistent vomiting, or diarrhea
- Hemoglobin < 6 g/dl, white blood cells < 2500/mm3, serum creatinine > 1.5 mg/dl, AST and ALT > 2X upper limit of normal.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01704144
|Contact: Awewura Kwara, MD, MPH&TM
|Contact: Sampson Antwi, MBChB
|Komfo Anokye Teaching Hospital
|Kumasi, Ghana
|Contact: Sampson Antwi, MBchB +233265812061 firstname.lastname@example.com
|Contact: Anthony Enimil, MBChB +233208164433 email@example.com
|Principal Investigator:
|Awewura Kwara, MD, MPH&TM
|The Miriam Hospital
No publications provided
|Responsible Party:
|The Miriam Hospital
|ClinicalTrials.gov Identifier:
|NCT01704144 History of Changes
|Other Study ID Numbers:
|Study First Received:
|October 4, 2012
|Last Updated:
|October 16, 2012
|Health Authority:
|Ghana: Committee on Human Research
Keywords provided by The Miriam Hospital:
Drug-drug interactions
Drug-gene interactions
Additional relevant MeSH terms:
Actinomycetales Infections
Bacterial Infections
Gram-Positive Bacterial Infections
Mycobacterium Infections
Anti-Bacterial Agents
Anti-Infective Agents
Anti-Retroviral Agents
Antibiotics, Antitubercular
Antitubercular Agents
Antiviral Agents
Enzyme Inhibitors
Leprostatic Agents
Molecular Mechanisms of Pharmacological Action
Nucleic Acid Synthesis Inhibitors
Pharmacologic Actions
Reverse Transcriptase Inhibitors
Therapeutic Uses
ClinicalTrials.gov processed this record on October 13, 2015