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Johan Santana to have MRI on his back
The Mets said after Monday's game that Johan Santana will have an MRI on his back, though he is still on schedule to start Thursday.
Matthew Cerrone, Lead WriterMonday morning I said I expected Johan to make one more start (this Thursday) and that's it. I figured, with the off day one week from today, they could drop back to five guys for the week, skip Johan and then replace him with Jenrry Mejia the next time through (as it will be after September 1). However, I wonder if this MRI will lead to yet another season-ending trip to the DL for Santana, who can then be immediately replaced in the rotation by Mejia before September.
Aug. 20, 5:03 pm: Collins said earlier today, while Santana's shoulder is healthy, he is experiencing a stiff back and lingering issues associated with the ankle injury that landed him on the disabled list earlier this season.
According to Collins, Santana will be on strict pitch count of less than 100.
GM Sandy Alderson later said Santana could be shut down after rosters expand Sept. 1, at which point the team might revert back to a five-man rotation.
"We think Johan is good for another start or two minimum," Alderson explained.
Aug. 20, 3:33 pm: Santana made his scheduled bullpen session earlier today at Citi Field.
This weekend, it was reported that Terry Collins, Dan Warthen and Sandy Alderson would discuss today what to do with Santana the remainder of the season.
In 10 starts since his no-hitter, Santana is 3-7 with an 8.27 ERA.

subset: commoncrawl


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tekenaars Artist: David Finch Jason Fabok
Artist David Finch Jason Fabok
Beschikbare series in de webshop categorie "Stripboeken"
David Finch in the
"Comic book artist David Finch began his career working for Top Cow Productions. He succeeded Marc Silvestri on 'Cyberforce', and co-created 'Ascension' with Matt Banning. He also worked on the first issues of 'Aphrodite IX'. He left the field for a while, and then returned in 2003 for a..." [ Lees meer ]


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JAKE GROVE/UPSTATE BE El Jimador is on Pearman Dairy Road in Anderson.
Above: Servers bring drinks and chips and salsa as soon as they seat you in El Jimador. Left: El Jimador offers fajitas, tacos, quesadillas, burritos and so much more on its menu.


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text: Pac-12 Tour in Colorado: 'It's not just playing, it's playing to win' Share this story email Share this story «Previous 2 of 5 Photos Next » Read the story « » Colorado Buffaloes Pac-12 tour "One of the things we always talk about is it's not just playing, it's playing to win," he said. "There's a difference in just playing, and playing to win. It's how you prepare, it's how you practice, it's all the things you do."


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Karlo, Robert and Župančić, Božidar and Škarica, Rade and Dunatov, Tihomir and Bačić, Ivan and Medić, Marko and Zadro, Zvonko (2007) Fist fractures at child's age. Collegium antropologicum, 31 (4). pp. 1003-1008. ISSN 0350-6134 (Print)


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Vegetarian celebs: Stars who pass on meat
Former Smiths frontman, PETA spokesperson and dedicated vegetarian Morrissey pulled out of and appearance on "Jimmy Kimmel Live" this week because the cast members from "Duck Dynasty" were going to be on as guests. Take a look at other famous vegetarian celebrities.
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By RICHARD SHAWSun Advocate publisher
Editor's Note: This is one of a series of articles about the history of the Sun Advocate and the county it covers as a newspaper. The article is being written from front page stories that appeared during each year in commemoration of the 120th anniversary of the newspaper's birth in 1891.
The year began with the College of Eastern Utah Prehistoric Museum fighting to keep the skeleton of the woolly mammoth found near the dam at Huntington Reservoir in 1988. The mammoth was found on United States Forest Service land and the Forest Service had written a proposal for acceptance and care of the bones that Don Burge, curator and director of the CEU Museum, said was worded so that only three facilities in the state could accept them. CEU was one of them. The college said it would fight the trend that had emerged over the years to not award findings such as the mammoth to the area in which they were found but to some other institution.
In mid-January the Helper City Council voted to drop the Helper Parkway Project entirely. A group called Concerned Citizens who felt the idea was not a good use of taxpayer funds had opposed the parkway from the time they found out about it when some river bed alteration plans were brought to their attention.
The execution of mass murderer Ted Bundy in Florida also became big local news in Carbon County. Just before he was executed, Bundy revealed some information that led authorities to believe that the body of Susan Curtis, who had disappeared from a BYU conference in June 1975, might be buried somewhere within 20 miles of Wellington. Bundy gave a vague description of where her remains lay, but by pinpointing the information the Carbon/Emery County area came under scrutiny. Although Bundy had been suspected in her disappearance, no one ever really stuck it on him. The one thing about her was that she fit the model of most of the girls Bundy either abducted, was suspected of abducting or had tried to abduct.
Ridge Road also was a great topic of discussion in 1989. Because of the large coal trucks transporting coal through areas of the county, it was thought that by taking at that time a narrow poor two lane road and turning it into a road that could be used by those trucks not only time would be saved but safety would be increased. It seemed almost everyone supported the road except, as was reported in February, the town of Wellington did not. The town's officials felt it would detract from the business development plan they had for the area. Then a couple of weeks later a number of Miller Creek residents came out against the idea as well, citing safety concerns about the expanded role of the road. However, in March the Permanent Community Impact Board awarded the county $2.5 million to build the road after Wellington's objections were withdrawn.
In February a hearing was convened by POST to determine if Carbon County Sheriff Barry Bryner would be able to hang onto his peace officer certification, based on facts uncovered during a probe by the agency in 1988. The hearing concluded with only two of the 40 witnesses listed testifying and no decision at that point. The next week County Commissioner Linda Varner called for Bryner's resignation after Bryner admitted to several things and having said he lied about those things.
Later that month another investigation was released which was related to evidence tampering within the sheriff's department. And in the Feb. 21 issue of the Sun Advocate it was announced that the Utah Sheriff's Association had expelled Bryner from the organization. It was the first time in the history of the group that they had ever done that. Finally at the end of the month, under duress and pressure, Bryner apparently lost control of not only the situation, but his actions.
On the morning of Feb. 22. Bryner was spotted in Helper about 3 a.m. drinking and a Helper officer warned him not to drive. However Bryner tried to get into his car she gave him one sobriety test. When she tried to administer another he uttered an epithet and ran to his car and sped off. She chased him at speeds of over 100 mph towards Price and then on to Wellington.
He then turned around and drove toward Price blasting through road blocks in his three day old police cruiser. As he attempted to to leave the by-pass road on the south Price exit, his car went out of control and became airborne. He crashed into a field where he was apprehended. A deputy approached the car and saw that Bryner had a gun in his hand. A call for help went out and police agencies from around the area responded.
Even though he was surrounded Bryner refused to surrender. He began a conversation while holding the gun with Deputy Jerry Cowan and eventually Cowan and Price Police Chief Aleck Shilaos wrestled the gun from him. He was arrested and taken by ambulance to Castleview Hospital. While Bryner's problems had begun many years before, they just grew in the coming months, as he was held accountable for the things he had done that night.


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Editor's Note: This is a free edition of The Technical Indicator, a daily MarketWatch subscriber column. To get this column, including 100 technical stock picks every month, click here.
CINCINNATI (MarketWatch) — While the major U.S. benchmarks trend higher, the Nasdaq has reached a significant technical test.
The specific level holds at the 2012 peak — Nasdaq 3,197 — and for the near term, this area marks the bull/bear battleground.
The S&P 500's hourly chart over the past two weeks shows the index has edged to yet another five-year high.
Initial support continues to hold at its breakout point of 1,515.
Meanwhile, the Dow industrials' near-term backdrop is slightly weaker.
The blue-chip benchmark is traversing a two-week range.
From current levels, initial resistance holds at last week's high of 14,022, while notable support rests at the range bottom, around Dow 13,860.
And the Nasdaq has rallied to a significant technical test.
Specifically, major resistance holds at the 2012 peak of 3,197, better illustrated below.
Widening the view to six months adds perspective.
On this wider view, two technical areas stand out:
- Nasdaq resistance at the 2012 peak of 3,196.93.
- Last week's high — Nasdaq 3,196.89.
More plainly, the Nasdaq tagged its 12-year high last week — almost to the decimal — and has initially balked at the resistance point.
Moving to the Dow, its six-month backdrop remains stronger.
Specifically, the blue-chip benchmark has sustained the 2013 breakout, establishing a two-week bullish flag.
Its tight range suggests that selling pressure remains limited, keeping market bulls on offense.
Meanwhile, the S&P 500 continues to trend above its 20-day moving average — currently 1,498 — and its path of least resistance points higher barring a violation of this area.
The bigger picture
As detailed above, the major U.S. benchmarks are holding a strong uptrend.
To start, the S&P 500 Index and the Dow Jones Industrial Average have sustained a break to five-year highs.
And at the same time, the Russell 2000 Index and S&P MidCap 400 Index are holding all-time highs.
Against this backdrop, the Nasdaq Composite has reached the U.S. markets' headline technical test.
As detailed previously, two technical areas stand out:
- Nasdaq resistance at the 2012 peak of 3,196.93.
- Last week's high — Nasdaq 3,196.89.
To the extent that the Nasdaq holds tightly to resistance, the chances of a breakout improve.
And widening the view to 25 years, the Nasdaq's monthly chart adds perspective. Each bar on the chart above represents one month.
Consider that a break from the 2012 peak would place the index in less-charted territory and its next technical resistance is poorly defined.
That's bullish.
Separately, a breakout would mark an extension from a loosely drawn trend line originating at the Nasdaq's 1987 low.
Meanwhile, the S&P 500's backdrop is different, though still constructive.


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To cover or not: Employers weigh health insurance options
Company number crunchers are stressed. Workers twist in limbo. But health insurance advisers predict that when employers master the new math and consequences of Obamacare, most will opt to keep providing coverage.
The online insurance exchange, the marketplace that is a cornerstone of federal health care reform, starts Jan. 1. So does the mandate that all California companies with at least 50 full-time equivalent employees face penalties if they don't provide insurance that pays for at least 60 percent of their workers health care costs.
The fear, pushed by premium prices expected to rise higher and faster, is that employers will decide they can save money by dropping their insurance and absorbing the $2,000 per full-time employee penalty. Their workers would be pushed toward the new exchange, maybe with a salary hike aimed at defraying their burden, maybe not.
At Clean Diesel Technologies Inc. in Ventura, no decisions have been made. Company leaders say they need to know more about how the insurance exchange would work and how any decision they do make would affect their workers.
But they are intrigued by a provision of the law that means they would be exempt from penalties for their first 30 employees. If they dropped their insurance and sent employees to the new insurance market — the health benefit exchange — they would have to pay fines for only 50 of their workers.
"We do have to take a look at different options," said the company's human resources director, Alex Rivera, adding that decisions are driven by not only by the cost of the premiums but the cost of coordinating the coverage. "It may be in the future because perhaps it would alleviate some of the administrative burden for a company like ours."
There will be sticker shock come Jan. 1, said Chuck Rosen, of Simi Valley, president of the California Association of Health Underwriters. Some employers will also have to pay more to increase their benefits. Plans not only have to pay for at least 60 percent of health costs, but an employee's share of coverage can't exceed 9.5 percent of his or hers household income.
But if employers drop coverage, they'll have to pay the fines. They'll lose the tax write-off that comes with providing insurance. An employee who doesn't qualify for subsidies could end up paying more because their premiums won't be sheltered from taxes.
It means workers will expect more money to cover the dropped benefit.
"He's going to go back to his employer and say I need a raise. I can't afford my premium," Rosen said. "It's very, very shortsighted for an employer to drop that coverage. It very well may cost them more money in the long run. Number two, it's just going to alienate their employees."
Some companies are considering other options. Callan Carter, a San Francisco employment benefits lawyer, said one of her clients has decided to restructure a mid-sized company into four small businesses with fewer than 50 full-time equivalent employees. That means the firms will be exempt from the mandate to provide coverage.
Other employers are limiting their work weeks to 29 hours so workers will be defined as part time. Some companies are considering offering increased pay to help their employees shoulder the burden of insurance.
"I have heard some employers say 'Can I just drop my health insurance and just give them $200 a month?' " Carter said. "The answer is, 'Sure, but you still have to pay the fine.' "
Carter thinks that cost calculations may show many employers that they could save money by not offering insurance.
But she also thinks the vast majority of employers will decide to keep their coverage, partly because they compete for workers with other businesses. Providing insurance allows them to protect and retain their employees.
"Employers are wary of just dumping their employees on the exchange for fear it will be a mess," she said.
Other advisers cite tax advantages and penalties that include a fine of $3,000 for each employee who leaves a company plan that doesn't meet government standards and ends up in a subsidized plan on the exchange.
"I'm sure that some employers will decide to drop coverage this year," said Marian Mulkey of the California HealthCare Foundation. "I really think if they're thinking through all their options, most might look at it ... but they probably wouldn't do it."
If large companies save money by dropping insurance, it won't be much, said John J. Nelson, co-CEO of the Warner Pacific Insurance Services in Westlake Village that employs about 100 people. Providing insurance is about more than the bottom line, he said.
"You can't measure it in strict monetary terms," he said, noting that opting out is not an option at his company. "Morale is important. Security is important. How do you put a price on that?"
California Retail Systems in Ventura pays about $8,000 a month to cover its 11 employees. Because of its size, the company is exempt from the Obamacare mandate to cover insurance. And if prices continue to rise, the decision of whether to provide coverage may be made for them.
"It all depends on cost," said Lorraine Lisle, the company's assistant general manager, noting that a decision on next year's coverage hasn't been made. "We are taking this month by month."
The exchange includes an arm aimed at small businesses. As of Jan. 1, businesses with fewer than 50 employees can buy group insurance through the exchange. Some will qualify for a 50 percent federal tax credit.
If employers are confused about the options, so are their employees. Debbi Thompson, of Simi Valley, works for a manufacturer that may be small enough to be exempt from health care reform. She's not sure because she knows little about Obamacare and less about the online insurance marketplace.
What she does know is that she was paying $40 a month for insurance. Now she pays $88 a month.
"If it doubles again, I'm probably not going to be able to afford health care. It's ridiculous," she said, offering an option other than the Affordable Care Act. "Just don't get sick."
Paying the penalty
Businesses with 50 or more full-time equivalent employees will face fines for not providing coverage.
Those fines kick in if one full-time employee receives government subsidized care on the exchange. Subsidies start for people who make up to 400 percent of the federal poverty level, meaning $92,200 for a family of four.
Penalties include a $2,000 fine for every full-time employee in a company. A business is exempt for its first 30 full-time employees.
If a company offers a plan that doesn't meet government standards, it faces a $3,000 fine for every full-time employee that goes to the exchange and receives subsidized coverage.
Subscribe to the Ventura County Star
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Welcome to Smogon! Check out the Smogon Info Hub for everything you need to know about starting out in the community. Don't forget to introduce yourself in the Introduction Thread, too!
Welcome to Smogon Forums! Please take a minute to read the rules.
Welcome to Wi-Fi! Please remember to read the rules and do NOT create a new thread for simple trades or Friend Safari codes.
Collectors Paradise
Discussion in 'Wi-Fi' started by Buckert, Dec 18, 2010.
Page 38 of 80
Page 38 of 80


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The parents of Jonathan Fausett and Rachel Kohlbrand announce the recent marriage of their children on Dec. 15 in the Logan LDS Temple. A reception will be held in their honor in Midland, Mich. on Dec. 21.
Jonathan is pursuing a pre-med degree at Utah State University in Logan. Rachel is studying biological engineering at USU.
Jonathan is the son of Terri Fausett and the late Gregory Fausett. He is the grandson of Grant and Betty Fausett and John and Sonja Godbout.
Rachel is the daughter of Henry and Janice Kohlbrand. She is the granddaughter of Betty Miller, the late Ralph Miller and the late Henry and Louise Kohlbrand.


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In most cases your BlackBerry device automatically connects to the appropriate wireless network when you travel outside of your wireless service provider's coverage area. In some cases you must contact your provider to have your micro SIM card or device properly provisioned. If you're not sure if your device is set up for roaming, or what roaming fees will apply, it's a good idea to check with your wireless service provider before you travel.
Your BlackBerry device is designed to switch to an appropriate wireless network automatically when you travel, but you might need to try switching networks manually if you're having trouble connecting or if the network signal is weak.
To switch wireless networks manually, your wireless service plan must include this service and your device must be connected to a GSM or UMTS network.
Depending on your wireless service plan, you might be able to turn off data services (email messages, PIN messages, text messages with attachments, and browser service) on your BlackBerry device so that only the phone and basic text messaging are available.Turning off data services while roaming might prevent you from receiving additional roaming charges. For more information, contact your wireless service provider.


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CREATE COOL BAND BRACELETS WITH FUNLOOM™! Kit contains everything you need to make one-of-a-kind jewelry accessories for friends and family. The included loom is super-easy to use—just load it with the multi-color silicone rings, use the hook to weave them into fun zigzag patterns, and then affix a C-clasp to hold your new bracelet together. You get 1 loom, 1 hook, 300 assorted color rings, 15 C-clasps, instructions. For ages 6 and up.
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text: Arkansas is home to amazing events year-round. If you are looking for Arts & Culture, Family, Outdoor, Festivals, Sports or Free Arkansas events, we have something for everyone. Search below to find a variety of Arkansas festivals, performances and other events and start creating your trip today! If you would like to submit Arkansas events to our calendar, click here. Arkansas Events Search Quick Searches: Today / This Week / This Month Start Date: End Date: And/Or City: All Amity Arkadelphia Ash Flat Augusta Batesville Beebe Bella Vista Benton Bentonville Bismarck Bluff City Bradley Brinkley Bryant Bull Shoals Calico Rock Camden Cave City Cherokee Village Clarksville Clinton Conway Corning Cotter Crossett Dardanelle De Queen Deer Des Arc DeValls Bluff Dierks El Dorado Emerson Eureka Springs Fairfield Bay Fayetteville Fifty Six Fordyce Forrest City Fort Smith Garfield Gentry Gillett Glenwood Gravette Greenbrier Greenwood Greers Ferry Halley Hampton Hardy Harrisburg Harrison Hatfield Hazen Heber Springs Helena-West Helena Hindsville Holiday Island Hope Horseshoe Bend Hot Springs Hot Springs Village Hoxie Huntsville Jacksonville Jasper Jersey Jessieville Jonesboro Kirby Lake Village Lakeview Leslie Little Rock Lowell Magnolia Mammoth Spring Marble Falls Marianna Marion Marshall Marvell Maumelle McGehee McNab McNeil Melbourne Mena Monticello Morrilton Mount Ida Mount Judea Mountain Home Mountain Pine Mountain View Mountainburg Mulberry Murfreesboro Newport Norman North Little Rock Ozark Paragould Paris Parkin Perryville Piggott Pine Bluff Pocahontas Powhatan Prairie Grove Prescott Rison Rogers Roland Russellville Salesville Scott Searcy Sheridan Sherwood Siloam Springs Smackover Springdale Star City Stuttgart Texarkana Tontitown Tyronza Van Buren Walnut Ridge Warren Washington West Fork West Memphis White Hall Wickes Wilson Witts Springs Wye Wynne Category: All Agritourism Arts & Crafts Camps Camps,Film Cook-Offs Cook-Offs,Festivals Fairs & Rodeos Fairs & Rodeos,Festivals Farmers Market Festivals Festivals,Motorcycling Festivals,Music Film Fine Arts Food Events Food Events,Holiday Events Food Events,Nature Fundraisers/Benefits Heritage & History Holiday Events Holiday Events,Performing Arts Holiday Events,Sporting Events Long Term Events & Exhibits Markets, Sales & Auctions Motorcycling Music Nature Pageants Performing Arts Shows & Expositions Sporting Events Trail Events, Hikes & Floats Workshops, Demonstrations & Seminars Keywords: Area: All Central Lower Delta North Central Northwest Southwest Upper Delta Include Long-Term Events Include State Parks Programs & Events Near Me Accessible Kid Friendly Pet Friendly SEARCH [ Reset All Qualifications ] View: 10 per page 25 per page 50 per page 100 per page No results matched your search! Showing 1 - 0 of 0 Page: View: 10 per page 25 per page 50 per page 100 per page


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42 U.S. Code § 9656 - Transportation of hazardous substances; listing as hazardous material; liability for release
(a) Each hazardous substance which is listed or designated as provided in section 9601 (14) of this title shall, within 30 days after October 17, 1986, or at the time of such listing or designation, whichever is later, be listed and regulated as a hazardous material under chapter 51 of title 49.
(b) A common or contract carrier shall be liable under other law in lieu of section 9607 of this title for damages or remedial action resulting from the release of a hazardous substance during the course of transportation which commenced prior to the effective date of the listing and regulation of such substance as a hazardous material under chapter 51 of title 49, or for substances listed pursuant to subsection (a) of this section, prior to the effective date of such listing: Provided, however, That this subsection shall not apply where such a carrier can demonstrate that he did not have actual knowledge of the identity or nature of the substance released.
Source(Pub. L. 96–510, title III, § 306(a), (b),Dec. 11, 1980, 94 Stat. 2810; Pub. L. 99–499, title II, § 202,Oct. 17, 1986, 100 Stat. 1695.)
In subsecs. (a) and (b), "chapter 51 of title 49" substituted for "the Hazardous Materials Transportation Act [49 App. U.S.C. 1801 et seq.]" on authority of Pub. L. 103–272, § 6(b),July 5, 1994, 108 Stat. 1378, the first section of which enacted subtitles II, III, and V to X of Title 49, Transportation.
1986—Subsec. (a). Pub. L. 99–499, § 202(a), substituted "within 30 days after October 17, 1986" for "within ninety days after December 11, 1980" and inserted "and regulated" before "as a hazardous material".
Subsec. (b). Pub. L. 99–499, § 202(b), inserted "and regulation" after "prior to the effective date of the listing".
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


text: Monday Aug 3 Philadelphia magazine's Be Well Philly Health & Hero Challenge Philadelphia magazine's Be Well Philly wants to know about local champions of health and wellness —family, friends, teachers, coaches, trainers, co-workers — anyone who's truly helping others make strides for healthier lives. The winner will be named the 2015 Health Hero and a donation will be made to the charity of his or her choice. Read more at http://www.phillymag.com/healthhero


text:
Welcome to Smogon! Check out the Smogon Info Hub for everything you need to know about starting out in the community. Don't forget to introduce yourself in the Introduction Thread, too!
Welcome to Smogon Forums! Please take a minute to read the rules.
CAP 9 CAP 9 - Part 11 - Counters Discussion
Discussion in 'CAP Process Archive' started by Plus, Oct 19, 2009.
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- Not open for further replies.
Page 1 of 3
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text:
When Jules and Mel return from a girls' weekend vacation, they board an airport shuttle for the short ride home. But the trip slowly descends into darkness after a detour into a seedy neighborhood leads to a series of terrifying events that leave Mel, Jules and the other passengers fighting for their lives.
Cast: Tony Curran, Peyton List, Cullen Douglas, Tom Kemp, Cameron Goodman
Produced by:
Directed by: Edward Anderson
Written by: Edward Anderson
Running time: 1hr 46min
Opens: Mar 06, 2009 LA
|Theaters for Today
Pick a day
on this day.


text:
Eplerenone in HIV Associated Abdominal Fat Accumulation
- Full Text View
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to test the effects of a drug, eplerenone, along with lifestyle modification to affect sugar metabolism, body fat distribution, and cardiovascular health in HIV-infected individuals. In non-HIV-infected individuals, recent data has shown that aldosterone, a hormone that regulates salt and water balance, is increased in association with increased belly fat and decreased insulin sensitivity. In HIV-infected individuals, aldosterone appears to be higher in individuals with increased belly fat, and increased aldosterone appears to be strongly associated with impaired sugar metabolism. In this study, the investigators will test the effects of eplerenone, which is a medication that blocks the actions of aldosterone, along with lifestyle modification. The investigators hypothesize that eplerenone may improve sugar metabolism, improve markers of cardiovascular health, and reduce fat accumulation in liver and muscle.
Drug: Eplerenone and lifestyle
Other: placebo and lifestyle
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|Randomized Placebo-controlled Trial to Investigate the Effects of Eplerenone in Patients With HIV-associated Abdominal Fat Accumulation
- Insulin stimulated glucose uptake [ Time Frame: 6 months ] [ Designated as safety issue: No ]Insulin stimulated glucose uptake measured during euglycemic hyperinsulinemic clamp procedure
- visceral adipose tissue [ Time Frame: 6 months ] [ Designated as safety issue: No ]visceral adipose tissue area as measured by single-slice computed tomography scan of the abdomen
- liver fat [ Time Frame: 6 months ] [ Designated as safety issue: No ]hepatic (liver) fat as measured by magnetic resonance spectroscopy
- intramyocellular lipid [ Time Frame: 6 months ] [ Designated as safety issue: No ]intramyocellular lipid of calf muscles as measured by magnetic resonance spectroscopy
- flow mediated vasodilation [ Time Frame: 6 months ] [ Designated as safety issue: No ]
- potassium [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]serum measurements of potassium
- hemoglobin A1c [ Time Frame: 6 months ] [ Designated as safety issue: No ]
- c-reactive protein [ Time Frame: 6 months ] [ Designated as safety issue: No ]
- plasminogen activator inhibitor 1 [ Time Frame: 6 months ] [ Designated as safety issue: No ]
- adiponectin [ Time Frame: 6 months ] [ Designated as safety issue: No ]
|Estimated Enrollment:
|Study Start Date:
|January 2012
|Estimated Primary Completion Date:
|August 2017 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Eplerenone and Lifestyle
First 6 months: eplerenone 50mg daily along with lifestyle modification (counseling regarding lifestyle and diet, as well as following healthy activity guidelines) Second 6 months: same (eplerenone open label during second 6 months)
Drug: Eplerenone and lifestyle
eplerenone 50mg by mouth daily as well as lifestyle counseling
Placebo Comparator: Placebo and Lifestyle
First 6 months: placebo pill daily along with lifestyle modification (counseling regarding lifestyle and diet, as well as following healthy activity guidelines) Second 6 months: eplerenone (open label) 50mg daily along with continued lifestyle modification
Other: placebo and lifestyle
placebo pill daily and lifestyle counseling
Detailed Description:
The study is 12 months long, with two phases. In the initial, 6-month phase, volunteers are randomly assigned to receive either eplerenone or placebo (an inactive pill). In addition, all volunteers will receive counseling about healthy diet and lifestyle, and will be asked to follow guidelines for a healthy level of physical activity. In the second 6-months of the study, all volunteers will continue to receive lifestyle modification and all will receive eplerenone.
|Ages Eligible for Study:
|30 Years to 65 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Increased waist circumference based on NCEP guidelines (>102cm in men and >88cm in women) and impaired glucose tolerance (either IFG > 100 mg/dL but < 126 mg/dL or 2hr glucose > 140 mg/dl but < 200 mg/dL, or fasting insulin >12 uIU/mL)
- HIV positive for 5y and on a stable ART regimen for at least 12 months
- Age ≥ 30 and ≤ 65 years of age
Exclusion Criteria:
- ACE Inhibitor, ARB, verapamil, or spironolactone
- Potassium supplementation
- Estimated GFR<60, creatinine > 1.5 mg/dL
- Serum K > 5.5 mEq/L, ALT > 2.5 times the upper limit of normal, Hgb < 11g/dL
- Uncontrolled hypertension (SBP ≥ 160 or DBP ≥ 100)
- Current or prior steroid use within past 6 months
- Known history of diabetes mellitus or current use of anti-diabetic medications
- Concomitant use of full dose ritonavir, nelfinavir, clarithromycin and other strong inhibitors of CYP34A
- Use of St. John's Wart (CYP3A4 inducer)
- Pregnant or actively seeking pregnancy, breastfeeding
- For women: Pregnant or actively seeking pregnancy, breastfeeding, failure to use an acceptable non-hormonal form of birth control, including abstinence, barrier contraceptives, or non-hormonal IUD.
- Estrogen or progestational derivative use within 3 months
- Testosterone use for non-physiologic purposes, or physiologic testosterone replacement for < 3 months.
- Current growth hormone or growth hormone releasing hormone use
- Current viral, bacterial or other infections (excluding HIV)
- Current active substance abuse
- Patients with a significant history of cardiovascular disease, including prior MI or stroke
Please refer to this study by its ClinicalTrials.gov identifier: NCT01405456
|Contact: Katie Fitch, NP
|United States, Massachusetts
|Massachusetts General Hospital
|Boston, Massachusetts, United States, 02114
|Principal Investigator:
|Steven Grinspoon, MD
|Massachusetts General Hospital
No publications provided
|Responsible Party:
|Steven K. Grinspoon, MD, Principal Investigator, Massachusetts General Hospital
|ClinicalTrials.gov Identifier:
|NCT01405456 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 27, 2011
|Last Updated:
|May 8, 2015
|Health Authority:
|United States: Institutional Review Board
Keywords provided by Massachusetts General Hospital:
visceral fat
Additional relevant MeSH terms:
Cardiovascular Agents
Diuretics, Potassium Sparing
Hormone Antagonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Mineralocorticoid Receptor Antagonists
Natriuretic Agents
Pharmacologic Actions
Physiological Effects of Drugs
Therapeutic Uses
ClinicalTrials.gov processed this record on October 09, 2015


text:
Hey Rob,
You provided some good help on this thread (http://registry.gimp.org/node/10774) concerning stippling but I need to take it to the next level. PC PMed me a cool site that creates Traveling Salesman plots but I need a way to convert point plots to X,Y coordinates (see link below to the site for Concorde program). Have any thoughts about this. I know that Sourceforge has GRI (http://sourceforge.net/projects/gri/files/) but to compile it for Windows is not an easy task for me; not even sure it will be what I want anyway. Any thoughts?
pertinent links:
http://www.oberlin.edu/math/faculty/bosch/making-tspart-page.html (can find a link to Concorde too, but also, the direct link is here (http://www.tsp.gatech.edu/concorde.html)).
To contact RobA maybe was better a PM
Anyway maybe also from here may come some useful suggestion
to the traveller salesman problem
maybe in software discussion ? or may be a mapmaking request?
anyway you need the xy coordinates of the cities visited by the
TS on a map of a place that has a shape as a smiley, or as Obama
or.whatever...and even better trace its travel path on the map
Expertize of cartographers may be useful
but maybe you will make somebody happy, maps for travelling salesman may be a fascinating challenge
And..did you explored the "Automation" section of the software discussion board ?
". Only reason I posted the request like this is that maybe others might be interested in the art potential of this. :)"
i am on something quite close i badly want a Voronoi Stippler
Gimp plugin, or Gmic filter or whatever
I stumbled on that TMS link when hunting for Voronoi Stippler and Hatching http://mrl.nyu.edu/~ajsecord/hatching/ codes and algorithms
Those are pretty interesting!
I know there is a voronoi plugin but it isn't tied to "density" at all, it just randomly created the centroids.
It would be nice for someone to write a plugin to do this as scripting would be too slow.
-Rob A>
a script may be too slow but looks as something that Mathmap could do without have to go troght the complication to create ( and create a Gui) for a C plugin, but offering a similar speed (and the possibility to "chain" it with other filters )
..except i am not able to transform in a mathmap expression
I posted the links also in the Gmic group since both looks as possible, and good "Artist filters"


text:
Big "D" 420 Chap Bag
The Big ''D'' 420 Chap Bag is great for storing your western chaps between shows! This nylon chap bag comes with one pocket and one hanger and can hold multiple pairs of chaps. Read more...
This 420 Chap Bag by Big "D" is carefully crafted with all-American patterned and quilted, tough 420 denier nylon to pad and protect your chaps in between shows. Designed with a quilted virgin fiber fill liner and a heavy duty zipper- these bags are designed and built to provide excellent protection.
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text:
Council Tax
Council Tax funds the services New Forest District Council provides together with those provided by Hampshire County Council, the Local Parish Councils, Hampshire Fire and Rescue Authority and the Hampshire Police Authority. Central Government gives every council a Revenue Support Grant, based on the needs, resources and population of the local area. However, this is never enough to finance all the services. To make up the difference each Billing Authority charges Council Tax.
New Forest District Council will bill and collect Council Tax of over £100million this year from more than 80,000 dwellings.
Complete your student review form on-line
Changes to unoccupied properties from 1 April 2013
Pay on-line now (you need to give your council tax number which starts 16....). or Set up a Direct Debit
Send us your enquiry by email (other links at bottom of this page) This is a standard form with limited space
Service Email Addresses (if you want to send a long email to us rather than being restricted to a standard form length) Select "Tax and Benefits" from the list of service departments
2015/16 council tax - how much, where the money goes
See what percentage we collected in the year it was due
The full year's Council Tax is payable over 10 monthly instalments, from 1 April to 1 January, due on the 1st of every month (choice of 1st or 15th by Direct Debit). You can ask to pay the year's council tax by 12 instalments instead of 10. The 'year' is the period 1 April to 31 March. If you get your council tax bill part-way through the year, the number of monthly instalments will be less than 10 (or 12) and will depend on how many complete months are remaining in the year. If you move into (or out of) your home part-way through the year, your council tax will be 'apportioned' on a daily basis.


text:
16 U.S. Code § 3113 - Definitions
As used in this Act, the term "subsistence uses" means the customary and traditional uses by rural Alaska residents of wild, renewable resources for direct personal or family consumption as food, shelter, fuel, clothing, tools, or transportation; for the making and selling of handicraft articles out of nonedible byproducts of fish and wildlife resources taken for personal or family consumption; for barter, or sharing for personal or family consumption; and for customary trade. For the purposes of this section, the term—
(1) "family" means all persons related by blood, marriage, or adoption, or any person living within the household on a permanent basis; and
Source(Pub. L. 96–487, title VIII, § 803,Dec. 2, 1980, 94 Stat. 2423; Pub. L. 105–83, title III, § 316(b)(4), (d),Nov. 14, 1997, 111 Stat. 1593, 1595.)
References in Text
This Act, referred to in provision preceding par. (1), is Pub. L. 96–487, Dec. 2, 1980, 94 Stat. 2371, as amended, known as the Alaska National Interest Lands Conservation Act. For complete classification of this Act to the Code, see Short Title note set out under section 3101 of this title and Tables.
1997—Pars. (3) to (5). Pub. L. 105–83, § 316(b)(4), which directed the addition of pars. (3) to (5) was repealed by Pub. L. 105–83, § 316(d). Pars. (3) to (5) read as follows:
"(3) 'customary and traditional uses' means the noncommercial, long-term, and consistent taking of, use of, or reliance upon fish and wildlife in a specific area and the patterns and practices of taking or use of that fish and wildlife that have been established over a reasonable period of time, taking into consideration the availability of the fish and wildlife;
"(4) 'customary trade' means, except for money sales of furs and furbearers, the limited noncommercial exchange for money of fish and wildlife or their parts in minimal quantities; and
"(5) 'rural Alaska resident' means a resident of a rural community or area. A 'rural community or area' means a community or area substantially dependent on fish and wildlife for nutritional and other subsistence uses." See Effective and Termination Dates of 1997 Amendment note below.
Effective and Termination Dates of 1997 Amendment
Until laws are adopted in Alaska which provide for definition, preference, and participation specified in sections 3113 to 3115 of this title, amendment by Pub. L. 105–83was effective only for purpose of determining whether State's laws provide for such definition, preference, and participation, and such amendment was repealed on Dec. 1, 1998, because such laws had not been adopted, see section 316(d) ofPub. L. 105–83set out as a note under section 3102 of this title.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


text:
hi all,
I've just installed php-nuke in my computer and I'm having a little trouble getting the forum to run.
it has this error saying:
Fatal error: Cannot instantiate non-existent class: overlib in var/www/html/nuke/modules/Forums/index.php on line 51
and when I look at line 51, it says
$ol = new OverLib();
am I missing a package or setting anywhere??
thanks heaps for help


text:
knucklehead document help request
i need something that shows how many horsepower an EL makes, and at what RPM. this doesn't have to be original Harley literature, and seems like it can be just about any form of printed material (restoration guide, etc is ok). if anyone has anything with that info on it, can you scan it for me?
i have Palmer's book and have looked through it, but unless i missed it, that info is not in there. the factory service manual only shows an NACC power rating, with no info about RPMs (which is not surprising if i understand the NACC power rating system correctly).
i know ELs are generally considered to produce 40 HP, but i need documentation of some form that shows that (and at what RPM that occurs).
if someone could point me in the right direction, it would be much appreciated.


text:
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Perfect for students who flourish in a self-paced learning environment, each consumable workbook combines lessons, exercises, projects, reviews and tests. Paperback.
Covers may vary.
|Format: Paperback
Vendor: Alpha Omega Publications
Dimensions: 11.0 X 8.5 (inches)
Availability: In Stock
Series: AOP Lifepac History & Geography
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