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Stock Market & Financial Investment News
News Breaks
January 27, 2014
Futures suggest a market bounce
U.S. equity futures are pointing to a higher open despite another decline in overseas markets today. Stocks in emerging markets are dropping sharply once again, as foreign currencies remain in a downward trend against the U.S. dollar. Meanwhile, investors will be watching earnings reports from Caterpillar (CAT) before the open and Apple (AAPL) and US Steel (X) after the close today for clues about the health of major corporations. Investors will also examine new home sales data for December for information about the housing market.
News For AAPL;X From The Last 14 Days
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September 28, 2015
Knowles upgraded on increased Apple content at FBR Capital
FBR Capital analyst Christopher Rolland upgraded Knowles (KN) to Market Perform from Underperform saying Chipworks identified a fourth mic made by the company in Apple's (AAPL) iPhone 6S, up from three in the previous version of the smartphone. Further, key Knowles competitor has encountered difficulties sourcing qualified MEMS wafers from its third-party manufacturing partner, Rolland tells investors in a research note. He raised his price target for shares to $18 from $17.
iPhone survey shows trend to higher capacity continues, says Piper Jaffray
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September 25, 2015
Stocks end week lower as biotechs sink, Volkswagen crashes
Stocks ended the week lower after concerns about drug prices were reignited, sinking biotech stocks, an emissions scandal engulfed Volkswagen (VLKAY), dragging down shares of automakers and their suppliers, and Caterpillar (CAT) announced that it may eliminate as many as 10,000 jobs in the next three years as commodity prices continue to slump. MACRO NEWS: Following the Federal Reserve's decision last week to wait before raising rates, the central bank made a concerted effort to give the market more clarity this week. Over last weekend, three Federal Reserve officials - San Francisco Fed President John Williams, St. Louis Fed President James Bullard and Richmond Fed President Jeffrey Lacker - all argued that an interest-rate increase is still warranted this year. Then, on Thursday night, Fed Chair Janet Yellen said during a speech at UMass Amherst that the central bank remains inclined to hike rates this year. Yellen's remarks were incrementally hawkish, but welcomed by the market, since they helped clarify the message the Fed delivered a week ago... In the U.S., Markit's flash manufacturing purchasing manager's index was flat at 53.0 in September, which was slightly better than the expectation for it to dip to 52.8. Durable goods orders for August declined 2.0%, versus expectations for a drop of 2.3%. When transportation items were removed, the core reading was breakeven, versus expectations for a rise of 0.1%. The third estimate of second quarter GDP showed the economy grew 3.9% quarter-over-quarter, versus expectations for the GDP growth estimate to stay at 3.7%. Personal consumption in Q2 is now believed to have grown 3.6%, up from the prior estimate of 3.1%. The final University of Michigan consumer sentiment reading for September came in at 87.2, which was down from August's 91.9 but above the expected 86.2 reading... The Asian Development Bank cut its growth forecast for the region, citing a weaker outlook for China and India and a delayed recovery in the world's advanced economies. The bank now sees the Chinese economy growing 6.8% this year and 6.7% next year, down from its previous forecasts of 7.2% and 7%, respectively. Markit's flash manufacturing PMI for China fell to 47.0 in September from 47.3 last month. Meanwhile, Japanese Prime Minister Shinzo Abe unveiled new economic targets, including a goal for a 20% increase in the target size of the Japanese economy to 600T yen, though he gave no timeframe for achieving this aspiration... In Europe, Markit's composite PMI for the eurozone came in at 53.9 in the first look for September, down from 54.3 in August and below expectations for a reading of 54.1. COMPANY NEWS: Biotech stocks declined after privately-held Turing Pharmaceuticals made headlines by enacting a 5,000% price increase on its treatment for toxoplasmosis, reigniting a debate around drug prices that previously embroiled costly Hepatitis C drugs including AbbVie's (ABBV) Viekira Pak and Gilead's (GILD) Sovaldi and Harvoni. Presidential candidate Hillary Clinton sent the debate to center stage by criticizing the "outrageous" prices of specialty drugs and laying out a plan to tackle "price gouging" in the specialty drug market. The NASDAQ Biotechnology index fell roughly xxx% for the week amid the attention paid to Turing's drug and Clinton's response... Volkswagen (VLKAY) shares trading in New York fell sharply to begin the week and ended the week far from where they'd been last Friday before the EPA said it found manipulations that violate U.S. environmental standards while testing certain of the automaker's diesel cars. The EPA said Volkswagen may face civil penalties of $37,500 for each vehicle not in compliance with federal clean air rules, which could total as much as $18B, according to Reuters. In the wake of the scandal, Chief Executive Officer Martin Winterkorn resigned, with the company's supervisory board subsequently praising the decision and selecting Matthias Mueller, the former head of Porsche (POAHY), as Winterkorn's successor as the company's new CEO... Caterpillar (CAT) shares dropped after the heavy machinery maker announced plans for job cuts and lowered its revenue guidance for this year and next. Caterpillar said that it would lay off 4,000-5,000 of its employees between now and the end of 2016 and could lay off up to 10,000 employees by 2018. Caterpillar cut its fiscal year 2015 revenue forecast by $1B and said its sees its fiscal year 2016 revenue to be 5% below this year, adding that it expects revenue declines in all three large segments next year... Online and mobile deal provider Groupon (GRPN) said it plans to cut 1,100 jobs relating primarily to the company's international operations... Nike jumped after the athletic gear giant reported better than expected earnings and futures orders, prompting numerous price target hikes and at least one upgrade at Street research firms. Among other companies reporting earnings this week, BlackBerry (BBRY), ConAgra (CAG), Carnival (CCL), and CarMax (KMX) fell immediately following their quarterly reports... Apple (AAPL), which has previously been reported to be working on an electric car via its "Project Titan," is speeding up those efforts and setting 2019 as a target to ship its first vehicle, according to The Wall Street Journal... Against the backdrop of China's President Xi Jinping visiting the U.S., Boeing (BA) announced deals to sell 300 planes to three Chinese companies and set up an aircraft factory in in the Asian nation, while Cisco (CSCO) announced a partnership with Chinese server maker Inspur Group... Lloyd Blankfein, Goldman Sachs (GS) Chairman and CEO, disclosed that he was diagnosed with lymphoma. "Fortunately, my form of lymphoma is highly curable and my doctors' and my own expectation is that I will be cured," Blankfein stated in an open letter that was shared by the bank... GoPro (GPRO) finished the week about xxx% lower after Barron's contended in a feature article last weekend that the company's stock could plunge another 30% to $25 as Apple, Sony (SNE) and others pressure the company's "one-hit wonder" products... On the M&A front, Atmel (ATML) agreed to be acquired by German chipmaker Dialog Semiconductor in a deal valued at roughly $4.6B and Starwood Waypoint (SWAY) announced a stock-for-stock merger agreement with Colony American Homes. INDEXES: The Dow lost about 0.43% to close at 16,314.67, the S&P 500 fell about 1.35% to close at 1,931.34, and the Nasdaq declined about 2.89% to close at 4,686.50.
On The Fly: Top stock stories for Friday
Stocks opened with sharp gains the day after Fed Chair Janet Yellen gave some clarity to the market by suggesting the Fed will most likely raise interest rates by the end of the year. During afternoon trading, the news flow slowed and the volume lightened on the buy side, leaving the sellers with the upper hand. The Nasdaq was the first index to move into negative territory, led by broad weakness in biotech stocks, while the Dow was helped to stay in the green by a big post-earnings move higher in Nike (NKE). The averages limped into the close, leaving the market with an interesting set-up to begin next week. Outside of stock news, it was certainly a headline packed day, as Speaker of the House John Boehner announced that he will resign at the end of October, Chinese President Xi Jinping continued his U.S. visit and Pope Francis addressed the United Nations while spending a second day in New York City. ECONOMIC EVENTS: In the U.S., the third estimate of second quarter GDP showed the economy grew 3.9% quarter-over-quarter, versus expectations for the GDP growth estimate to stay at 3.7%. Personal consumption in Q2 is now believed to have grown 3.6%, up from the prior estimate of 3.1%. The final University of Michigan consumer sentiment reading for September came in at 87.2, which was down from August's 91.9 but above the expected 86.2 reading... Federal Reserve Chair Janet Yellen said during a speech at UMass Amherst last night that the central bank remains inclined to hike rates this year. Yellen's remarks were incrementally hawkish, but welcomed by the market, since they helped clarify the message the Fed delivered a week ago. Of note, the Fed chair paused multiple times toward the end of her speech and received medical attention afterward, but returned to her regular schedule later in the evening, with the bank explaining that Yellen was dehydrated after a long day but was otherwise fine. COMPANY NEWS: Nike jumped $10.23, or 8.9%, to $125.02 after Thursday night's report of better than expected earnings and futures orders prompted numerous price target hikes at Street research firms. Additionally, Sterne Agee upgraded Nike to Buy from Neutral, saying it thinks the company is benefiting from its "global grass roots engagement with its customers," which enables it to meet its customers' needs and determine to what extent it can raise prices. The firm, which thinks that the company is continuing to gain share, has a $150 price target on the athletic gear giant... Biotech stocks, which were already having a bad week, ended the week on a down note, as the iShares NASDAQ Biotechnology Index (IBB) fell 4.9%, giving it a weekly decline of about 13%. Among the biggest large-cap losers in the space were Vertex (VRTX), which fell 7%, Regeneron (REGN), which dropped 6% and Celgene (CELG), which slid 4.8%. MAJOR MOVERS: Among the notable gainers was Jabil Circuit (JBL), which advanced $2.38, or 12.2%, to $21.88 after it reported higher than expected earnings and gave guidance for its November quarter that was significantly above expectations. Also higher was Cirrus Logic (CRUS), which gained $3.90, or 14.4%, to $31.03 after tear downs of Apple's (AAPL) iPhone 6S and 6S Plus led analysts to conclude that the chipmaker appears poised to obtain more revenue from the new devices than from the previous generation of the market-leading smartphone. Among the noteworthy losers was Finish Line (FINL), which fell $4.86, or 19.6%, to $19.91 after reporting second quarter revenue that missed expectations and saying it expects adjusted earnings this fiscal year to increase in a low single to mid single digits percentage from last year. Also lower following its earnings report was smartphone and software maker BlackBerry (BBRY), which slid 7.68% to $6.49 after the company posted a second quarter loss that was steeper than analysts expected. BlackBerry also confirmed press reports that it plans to launch a new phone that uses Google's (GOOG) Android operating system instead of its own proprietary BB10 OS. Shares of Aratana Therapeutics (PETX), which dropped $6.81, or 38.97%, to $10.68 after the company said that, based on "mixed clinical and scientific results," it does not believe that canine lymphoma products AT-004 and AT-005 in their current, first-generation forms will capture the desired lymphoma market opportunity. INDEXES: The Dow rose 113.35, or 0.7%, to 16,314.67, the Nasdaq fell 47.98, or 1.01%, to 4,686.50, and the S&P 500 added/slipped 0.90, or 0.05%, to 1,931.34.
Options Update; September 25, 2015
iPath S&P 500 VIX Short-Term Futures up 66c to 25.09. Option volume leaders: AAPL NFLX BAC FB AU NKE PFE INTC AMZN TSLA
Skyworks volatility low on tight price range
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Qualcomm volatility low as shares trend lower
Qualcomm (QCOM) current 30-day call option implied volatility is at 26, compared to a one-month ago level of 38, suggesting decreasing price movement for the chipmaker that appear poised to obtain more revenue from Apple's (AAPL) iPhone 6S devices.
Electronic contract manufacturers advance after Jabil reports earnings
Shares of contract electronic manufacturers Flextronics International (FLEX), Sanmina (SANM), and Celestica (CLS) are advancing after peer Jabil Circuit (JBL) posted quarterly earning last night that easily surpassed analysts' estimates. WHAT'S NEW: Jabil Circuit reported better-than-anticipated profit and revenue in the fourth quarter as revenue in its Diversified Manufacturing Services segment increased 47% on a year-over-year basis, and represented 41% of total company revenue. Jabil reported Q4 earnings per share of 53c on revenue of $4.68B against analysts' estimates of 45c and $4.55B. On the company's Q4 earnings conference call, Chief Executive Officer Mark Mondello said he anticipates continued growth across its DMS business, as the company "captures additional opportunities" in the markets that DMS serves. Mondello noted that those markets include audio, healthcare, consumer packaging, mobility, wearable technologies, and accessories. WHAT'S NOTABLE: Looking ahead, the company sees DMS in the first quarter up 33% year-over-year and guided to Q1 results that were far ahead of analysts' estimates. Jabil said it sees Q1 EPS of 72c-88c on revenue of $5.1B-$5.3B. Analysts were expecting EPS of 61c on revenue of $4.91B. Jabil also guided to fiscal year 2016 EPS of $2.60 ahead of expectations of $2.37. ANALYST TAKE: After Jabil reported higher than expected Q4 EPS, Stifel notes that the company's guidance for its November quarter was significantly above expectations. The firm thinks the company is benefiting from increased purchases of its diversified manufacturing products by Apple (AAPL). Stifel says that Apple is using Jabil's products for many of its products, not just iPhones, and it expects other customers to ramp up their purchases of the company's DMS products. Stifel kept a $25 price target and Buy rating on the shares. PRICE ACTION: Shares of Jabil Circuit are advancing almost 15% to $22.43 in midday trading. OTHERS TO WATCH: Shares of other contract manufacturers are also advancing, with Flextronics up 1.5%, Sanmina jumping 2.8%, and Celestica higher by 1.35%
Cirrus leads iPhone suppliers higher as analysts dissect 6S
Cirrus Logic (CRUS), Skyworks (SWKS) and Qorvo (QRVO) are among the chipmakers that appear poised to obtain more revenue from Apple's (AAPL) iPhone 6S devices than from the previous generation of the market-leading smartphone. Research firms issued notes today based on their analysis of "teardowns" of the new phones after they went on sale for the first time, beginning in Australia. TEARDOWNS: Apple's common practice when rolling out its newest iPhone models is for Australia to be its first launch market. The unboxing of iPhones when they become available for sale for the first time anywhere in the world is a much anticipated event among the tech giant's fans, as well as by Apple-focused blogs and Wall Street analysts who follow the company. Websites like iFixit have become well known for their "teardowns" of the devices, where they purchase, take apart and analyze the way in which the device is made and how it differs from previous models. These teardowns are closely watched by analysts and can sometimes be catalysts for the stocks of iPhone component suppliers. CIRRUS: Barclays analyst Blayne Curtis says teardowns of Apple's iPhone 6S indicate Cirrus Logic secured both a smart codec and boosted amp win in the new phone. The company's content in each phone is likely towards the upper end of his $3.50-$4.00 estimate, Curtis tells investors, noting that he views this as better than expected. Curtis thinks the 6S content, coupled with the "several new growth drivers" Cirrus outlined at yesterday's technology day, could reverse the negative sentiment on the stock. He keeps an Overweight rating on the name with a $39 price target. OTHER WINNERS AND LOSERS: Skyworks and Qorvo saw their content rise 22% and 25% respectively, Curtis estimated. NXP Semiconductors (NXPI) is continuing to supply the NFC and Secure Element chips for the 6S devices, but is no longer providing the sensor hub, the analyst reported. The company will lose about 50c per iPhone as a result of this development, but it did know that it would no longer be providing the hub before it provided its guidance in July, according to Curtis. STMicroelectronics (STM) is no longer providing the secure MCU for the iPhone 6S, Curtis added. WHAT'S NOTABLE: Other companies that are supplying iPhone 6S components include Qualcomm (QCOM), Texas Instruments (TXN), and Avago (AVGO), iFixit reported. After conducting checks, Craig-Hallum analyst Anthony Stoss estimated that Skyworks will obtain about $6.50 of revenue per iPhone, up from about $5.50 previously, while Qorvo's revenue per device will rise to $6.25 from $5.75 and Avago will see its revenue per device increase to about $6.75 from about $6.50, Stoss believes. The firm kept Buy ratings on Skyworks, Avago, and Qorvo. PRICE ACTION: In morning trading, Cirrus shares jumped $4.36, or 16%, to $31.49, Skyworks added about 3% and Qorvo rose 4%. Meanwhile, NXP gained about 2% and STMicroelectronics advanced 2.5%.
Apple launch day lines generally as expected, says Piper Jaffray
Piper Jaffray analyst Gene Munster said the line at the Apple store on 5th Avenue in New York was about 650 people long at 8 am EDT, compared to last year's record 1,880 people counted, but added that the shorter line was generally in-line with the firm's expectations. The analyst noted that iPhone "S" cycles have historically had shorter lines, that Apple has been promoting pre-orders and online sales, and that the addition of China as a launch country likely cut down on resellers that were in line. Munster said he's still comfortable with his 12M-13M unit estimate for the opening weekend and keeps an Overweight rating and $172 price target on Apple shares.
Cirrus Logic content in iPhone 6S better than expected, says Barclays
Barclays analyst Blayne Curtis says teardowns of Apple's (AAPL) iPhone 6S indicate Cirrus Logic (CRUS) secured both a smart codec and boosted amp win in the new phone. The company's content in each phone is likely towards the upper end of his $3.50-$4.00 estimate, Curtis tells investors in a research note. He views this as better than expected. Curtis thinks the 6S content, coupled with the "several new growth drivers" Cirrus outlined at yesterday's technology day, could reverse the negative sentiment on the stock. He keeps an Overweight rating on the name with a $39 price target. Cirrus is up $3.68 to $30.81 in early trading.
Apple iPhone 6S Plus teardown reveals chip suppliers, iFixit reports
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iPhone 6S teardown positive for Skyworks, Qorvo, says Craig-Hallum
Craig-Hallum analyst Anthony Stoss says Apple (AAPL) iPhone 6S teardowns indicate content increases for Skyworks (SWKS), Qorvo (QRVO) and Avago (AVGO). Ross estimates Skyworks' content in the phone rose to $6.50 versus $5.50 in the first versions of iPhone 6, Qorvo's content rose to $6.25 from $5.75 and Avago's content rose to $6.75 from $6.50. He believes RF content is increasing and reiterates Buy ratings on all three names.
Active equity options trading on open
Active equity options trading on open: AAPL BAC FB NKE NFLX PFE AU TSLA
Shopify announces new EMV credit card reader that accepts chip, pin, Apple Pay
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Jabil Circuit fiscal 2016 guidance 'solid,' says Stifel
After Jabil reported higher than expected Q4 EPS, Stifel notes that the company's guidance for its November quarter was significantly above expectations. The firm thinks the company is benefiting from increased purchases of its diversified manufacturing products by Apple (AAPL). Stifel says that Apple is using Jabil's products for many of its products, not just iPhones, and it expects other customers to ramp up their purchases of the company's DMS products. Stifel keeps a $25 price target and Buy rating on the shares.
Apple October volatility flat as new iPhone hits stores
Apple September weekly call option implied volatility is at 26, October weekly is at 30, October is at 29, November is at 33; compared to its 52-week range of 18 to 56, suggesting non-directional near term price movement and large November price movement.
Indian Prime Minister to meet with Apple, Google CEOs, WSJ reports
Indian Prime Minister Narendra Modi will meet this weekend with Google (GOOG) CEO Sundar Pichai, Facebook (FB) founder Mark Zuckerberg and Apple (AAPL) CEO Tim Cook, among others, The Wall Street Journal reports. According to industry insiders, the tech executives will use the visit to push for better market access in India as well as clearer regulation on investment and startups.
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Apple shifts 30% of lens modules orders to Kantatsu, DigiTimes reports
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U.S. Steel implied volatility of 79 at upper end of index mean range
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Thousands Of Students March In Support Of Education And The Welfare State
Protesters scuffle with police and shout slogans during a... News PhotoEducation,England,Fighting,Horizontal,Houses Of Parliament - London,International Landmark,Learning,London - England,Placard,Police Force,Protest,Protestor,Shouting,UKPhotographer Warrick PageCollection: Getty Images News 2012 Getty ImagesLONDON, UNITED KINGDOM - NOVEMBER 21: Protesters scuffle with police and shout slogans during a demonstration against education cuts, tuition increases and austerity outside the Houses of Parliament on November 21, 2012 in London, England. The demonstration march was organised by the National Union of Students and is the first national student protest since a series of violent protests against tuition fees two years ago. (Photo by Warrick Page/Getty Images)

subset: commoncrawl


text:
European Central Bank report on the results of the survey on the access to finance of SMEs in the euro area – October 2013 to March 2014 Publicado el: 30/04/2014, Última actualización: 23/06/2015
The report mainly provides evidence on changes in the financial situation, financing needs and access to financing of SMEs in the euro area, compared with large firms, during the preceding six months.
- Access to finance remains an important – albeit not the most pressing – concern
- SMEs report less of a deterioration in the availability of finance from external sources
- Financing difficulties remain broadly unchanged, with substantial cross-country differences
While access to finance remains an important concern, it trails finding customers and the cost of production or labour for SMEs in the euro area. The survey shows that SMEs reported in net terms an increase in their need for bank loans during the survey period. The difference between the percentage of firms reporting an increase and those reporting a decrease of their need for bank loans was 4%, similar to the previous survey round.
SMEs reported deterioration in the availability of bank loans, albeit less than in the previous survey round (-4% of respondents, in net terms, after -11% in the previous round). The survey results indicate a marginal decline in the rejection rate for euro area SMEs when applying for a loan (11%, down from 12%). The percentage of SMEs reporting access to finance as their main problem declined to 14% (from 16%).
The survey results suggest that financing conditions for SMEs continue to differ significantly across euro area countries and are in general more difficult than those of larger companies.
Download the report [700 KB]


text:
Impact on T Cell Immune Activation and Inflammation of Triptolide Woldifii in HIV-infected Immunological Non-responders (CACTrip12)
Recruitment status was Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This study is a prospective, multicenter, randomized, placebo-controlled clinical trial, to evaluate impact of Triptolide wilfordii on T cell immune activation and inflammation biomarkers in HIV-infected immunological non-responders.
Drug: Triptolide
Drug: cART
Drug: placebo
Phase 1
Phase 2
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
|Official Title:
|Study of Triptolide Woldifiion T Cell Immune Activation and Inflammation Biomarkers in HIV-infected Immunological Non-responders
- Changes of T cell immune activation and inflammation biomarkers [ Time Frame: baseline and at 4,8,12,24,36,48 weeks ] [ Designated as safety issue: No ]T cell activation and inflammatory biomarkers including CD8+HLA-DR+/CD38+, IL-6, D-dimer and hsCRP,soluble CD14 and CD163, PD-1, CCR5 and CD57 should be measured at baseline and at Wee4, W12, W24, W36, W48 follow-up visits.
- Changes of CD4 T cell count and number of participants with adverse events [ Time Frame: baseline and at 4,8,12,24,36,48 weeks ] [ Designated as safety issue: Yes ]Measurement of CD4 T cell count at baseline and different visit points when follow-up and numbers of participants with adverse events.
|Estimated Enrollment:
|Study Start Date:
|January 2013
|Estimated Study Completion Date:
|March 2015
|Estimated Primary Completion Date:
|July 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Placebo Comparator: placebo + cART
combined with antiretroviral therapy, the control group will take placebo 2 tabs tid per day lasting for 6 months and then switch to take Triplitode 2 tabs tid po for anther 6 months
Drug: Triptolide
Triptolide Wilfordii is a Chinese old herb which is widely used as a remedy for rheumatic diseases and nephropathy in China. It is approved that it can play a role as an immune modular.
Other Name: Tripterygium Wilfordii Hook F (TwHF)Drug: cART
Participants who will be enrolled in this trial would keep their previous combined antiretroviral therapy, such as zidovudine or stavudine plus lamivudine plus nevirapine or efavirenz.
Other Name: Antiretroviral therapyDrug: placebo
Placebo pills produced the same as Triptolide wilfordii.
Other Name: sugar pills
Experimental: Triptolide + cART
combined antiretroviral therapy, the experimental group will take Triptolide 2 tabs tid po per day for 12 months.
Drug: Triptolide
Triptolide Wilfordii is a Chinese old herb which is widely used as a remedy for rheumatic diseases and nephropathy in China. It is approved that it can play a role as an immune modular.
Other Name: Tripterygium Wilfordii Hook F (TwHF)Drug: cART
Participants who will be enrolled in this trial would keep their previous combined antiretroviral therapy, such as zidovudine or stavudine plus lamivudine plus nevirapine or efavirenz.
Other Name: Antiretroviral therapy
Detailed Description:
About 120 patients will be recruited from 4 HIV/AIDS clinical centers in China and randomized 1:1 into intervention group and placebo-controlled group. Triptolide wilfordii (20mg tid po) would be given to invention group for 24 weeks. T cell activation and inflammation biomarkers including CD8+HLA-DR+CD38+, IL-6, D-Dimer and high-sensitivity C-reactive protein (hsCRP), protein degradation-1 (PD-1), Ki67 ,soluble CD14 and CD163, PD-1, CCR5 and CD57 would be tested. Patients in placebo-controlled group will change to take Triptolide wilfordii (20mg tid po) for another 24 weeks. All patients will be followed up till 48 weeks. We hypothesis that Triptolide wilfordii might reduce immune activation and inflammation of HIV immunological non-responders and increase CD4 T cell count, which provides a new strategy for treatment of HIV-infected immunological non-responders.
|Ages Eligible for Study:
|18 Years to 65 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Continuous antiretroviral therapy > 24 months , and consistent HIV-RNA< 40 copies/mL more than 12 months ;
- 18-65 years old;
- Male or female;
- Good adherence and promise to follow-up;
- Inform Consent signed;
- CD4 T cells less than 250/ul .
Exclusion Criteria:
- Active opportunistic infection (not stable within 4 weeks 2 weeks ) or AIDS-related carcinoma;
- hemoglobin (HGB) < 9 g/dl 、 white blood cell (WBC) < 2000/ul 、 granulin (GRN) < 1000 /ul 、 platelet (PLT) < 75000 /ul 、 Cr >1.5x ULN 、 ALT or AST or alkaline phosphatase (ALP) >3x upper limit of normal (ULN) 、 total bilirubin (TBIL) >2x ULN 、 creatine kinase (CK) > 2x ULN;
- Pregnant or breastfeeding woman or woman with pregnancy plan;
- Active drug-user;
- Severe neurological defects;
- Active alcohol abuse;
- Severe gastrointestinal ulcer .
- End-stage disease such as cirrhosis, chronic obstructive pulmonary disease, congestive heart failure, recent myocardial ischemia,tumor, etc
- Those who are undertaking steroids, immunomodulator, anti-inflammatory agents
Please refer to this study by its ClinicalTrials.gov identifier: NCT01817283
|Contact: Wei LU, M.D.
|Peking Union Medical College Hospital
|Beijing, China, 100730
|Contact: Wei LU, M.D. 00861069155081 email@example.com
|Principal Investigator:
|Tai sheng LI, M.D.
|Peking Union Medical College Hospital
No publications provided
|Responsible Party:
|LI Taisheng, Peking Union Medical College Hospital, Peking Union Medical College
|ClinicalTrials.gov Identifier:
|NCT01817283 History of Changes
|Other Study ID Numbers:
|Study First Received:
|March 18, 2013
|Last Updated:
|March 22, 2013
|Health Authority:
|China: Food and Drug Administration
Keywords provided by Peking Union Medical College:
HIV-infected immunological non-responders
immune activation
CD4 T cell
Additional relevant MeSH terms:
Pathologic Processes
Alkylating Agents
Antineoplastic Agents
Antineoplastic Agents, Alkylating
Antispermatogenic Agents
Contraceptive Agents
Contraceptive Agents, Male
Immunologic Factors
Immunosuppressive Agents
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Physiological Effects of Drugs
Reproductive Control Agents
Therapeutic Uses
ClinicalTrials.gov processed this record on October 13, 2015


text:
At a Glance
|Deck 12, Aft
|Designed For:
|Adults and Pre-Teens & Teens and kids (42 inches or taller)
|Hours of Operation:
|Please check the Personal Navigator while onboard for specific times
AquaDuck is an exciting "water coaster" located on Deck 12, Aft aboard the Disney Dream. Developed by Disney Imagineers, this elevated water coaster is the first of its kind at sea.
During the ride, you will:
- Travel 765 feet through an acrylic tube
- Go on a thrilling journey up, down, around and off the side of the ship, through the Forward Funnel—down a span of 4 decks!
- Enjoy breathtaking views of the ocean and ship below—assuming you're brave enough to keep your eyes open during the ride
- Get a bird's-eye view of the new pools available to family, kids and adults aboard the Disney Dream
- Splash into a lazy river at the end of the plunge
Riders should note that:
- AquaDuck is designed for adults and children at least 42" or taller
- Single riders must be at least 54" or taller
- Children under 7 must ride with someone 14 years of age or older, provided the child is at least 42" tall
- No snorkel equipment or swim goggles are allowed in the pool
Operating hours are likely to vary, so once you're onboard check the Personal Navigator—the Disney Cruise Line daily newsletter detailing all there is to see and do—for the most accurate times.
Policies About Swim Accessories and Equipment
Please be aware of the following policies about swim accessories and equipment:
- Swim goggles that fit only over the eyes are permitted at all pools, hot tubs and water slides, with the exception of AquaDunk aboard the Disney Magic, where goggles are not allowed.
- Swim masks that cover the eyes and nose are permitted at all pools. They are not allowed on any slides, including AquaDuck.
- Snorkel tubes are not permitted at any pools, hot tubs or water slides
Policies About Swim Diapers
The United States Public Health Service requires that only children who are toilet trained are permitted to enter swimming pools and spas aboard cruise ships.
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JOTA-JOTI 2013 Certificate
Can I get a certificate for my involvement in this good activity,? ПеревестиПодробнее
20. Окт 2013
От Indonesia
If the condition is fixed, the first thing to do is evacuating people from buildings which have posibility to fall and burry people beneath them on the aftershocks. Then, Trying to find any comunication means which is still working right after the disaster like trying to operate cellphone, radio, internet nearby. If cellphone network is working, reaching related institution is good. Beside, reaching relatives to make a call to the related institutions is also posible. Then, run to phone booth to make a call or police station nearby to ask hel and use their radio system,.
In my place, there is such an organization whose duties is like police department. the name is SENKOM which stands for Sentra Komunikasi or in English we have it communication center. This organization have national communication system through handie talkie. The access is very wide (all over my country) and connected to the police headquarters. This is a professional organization to handle natural disaster since the members have got trainings of evacuating victims and dealing with natural disaster. Calling the call center of SENKOM is one of possible solutions to do after the earthquake.
This is my opinion. there also website of SENKOM but unfortunately it is available in Indonesian language only. there is also a picture of SENKOM's logo,.
Can I get a certificate for my involvement in this good activity,? ПеревестиПодробнее
the inaguration ritual as a new member,. "facial wash" with water which is mixed with red roses and white roses,. ПеревестиПодробнее


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Thursday, November 20, 2008
CrockPot Turkey and Wild Rice Soup Recipe
Day 325.
The weather has officially changed. I am running the heat in the morning, the guinea pigs have moved inside, and the flannel sheets are out of hiding. Last night, I finally finished reading "The Long Winter" to the girls. We have so much to be thankful for--- if you have kids that sometimes forget how richly blessed modern day life is, I highly recommend reading it aloud.
Anyway. Today I am thankful that I met Kalyn Denny at BlogHer, and I am so happy to have found her Turkey and Wild Rice Soup. Adam proclaimed it the best turkey soup he's ever had, and the kids each ate two bowls. I may have wept. I'm not sure.
The Ingredients.
adapted from Kalyn's Kitchen
--turkey carcass (if you don't have one, you can use 2 cups of cooked turkey)
--8 cups water (to make broth. if you don't have a carcass, use 8 cups chicken broth)
--1 chicken bouillon cube (only if you are using the carcass to make broth. Don't use if you're using broth.)
--2/3 cup uncooked wild rice
--1 yellow onion, chopped
--1 cup chopped celery
--1 cup chopped carrots
--1 tsp sage
--2 T balsamic vinegar
--2 cups spinach leaves (Kalyn used cabbage, but cabbage reminds me either of engorgement or the cabbage soup diet)
The Directions.
I used a 6.5 quart crockpot.
This is a 1 1/2 day project. We're going to use the turkey bones to make broth for the soup. If you are using chicken broth and 2 cups of turkey, bypass this step.
Put your turkey carcass into a crockpot, and cover with 8 cups of water. My carcass was only from a tiny turkey, so if you need to break the bones down to fit in your crock, do so.
My turkey was still stuffed with a quartered onion and some apple, so I didn't bother to add any vegetables to season the water. You may certainly add some onion, celery, or anything else you'd like to season the broth. The more meat and skin left on the bones, the more flavorful the broth.
Cover and cook on low overnight. I cooked the broth for 10 hours. In the morning, put on an apron to strain the broth with a colander. What? No apron? Perhaps you could use a brand-spanking-new "I Heart CrockPotting" one? Since I have a bunch of crockpots, I strained the broth into a new one. You might need to strain the broth into a big bowl, then dump it back into the crockpot.
Pick off the meat, and add it to the broth.
Chop up the vegetables (not the spinach), and add to the pot. Dump in the wild rice. Add the sage, bouillon cube, and balsamic vinegar. Stir.
Add two heaping handfuls of baby spinach to the pot. It will look like a lot, but will shrivel down nicely while cooking.
Cover and cook on low for 8-10 hours, or on high for 4-6. The soup is done when the vegetables have reached desired tenderness. There is a lot of volume here; this is a good candidate for a day when you are out of the house for a long time. No need to worry about it over-cooking.
The Verdict.
This is my new favorite soup. I love, love, love the hint of tartness from the balsamic vinegar, and how it darkened the broth. The wild rice exploded a bit, and actually resembled barley by the time we ate it. The kids ate a bunch, and I had at least 3 bowls throughout the day yesterday. We have a quart left, which I will happily serve for lunch.
Thank you, Kalyn!
50 comments:
I am SO excited about the crockpot gear - SO EXCITED! I just sent my husband an e-mail with the link entitled "what I want for Christmas!". Thanks, Steph! Also, the soup looks yummy. :)
- November 20, 2008 at 6:54 AM
- Cynthia said...
I am absolutely lovin' what I see! I can't wait to try some of this stuff out. Thank you! Thank you!
- November 20, 2008 at 7:12 AM
Once again another winning recipe! It sounds delicious, can't wait to get a turkey and give it a try!
What are we all going to do when the year is over without our daily recipe? Thank you so much for being faithful to your blog every day.
- November 20, 2008 at 7:49 AM
- Melissa Henning said...
looks great! It may be a stupid question, but can you use frozen spinach? i have a block of it that i'm wanting to get rid of.
- November 20, 2008 at 8:01 AM
- jen said...
I am so trying this!! I also just left you a Fabulous Award over at my blog because well, you are fabulous!
- November 20, 2008 at 8:01 AM
- Crockpot Lady said...
Hi Melissa,
not a stupid question! Put the soup together, and put the box of frozen spinach in a bowl to thaw while the soup is cooking. An hour or so before serving, squeeze the moisture out of the spinach and stir it in.
- November 20, 2008 at 8:06 AM
- An Apron Straitjacket said...
Yummmmm! I'm going to have to tuck this one away for after Thanksgiving.
- November 20, 2008 at 8:09 AM
My sister and I used to read "Long Winter" out loud to each other on really hot summer days (no AC in our house). It helped, seriously!
- November 20, 2008 at 8:27 AM
- Robin said...
This is just to say I LOVE the Little House book, and the Long Winter is one of my favorite. Actually they're all my favorite.
- November 20, 2008 at 8:34 AM
Dumb question, but if I am using broth and not a turkey do I still need to let the broth cook over night?
- November 20, 2008 at 9:13 AM
- Hannah A. said...
I've never heard the term "carcass" in reference to food before. I wonder why that is...
The recipe sounds really good though. I may even be able to get my hubby to try it. (He only likes soup from a can or full of beef... oh well!)
- November 20, 2008 at 9:28 AM
- Kalyn said...
Yaaay. I'm so glad I met you too, because you've inspired me to use the crockpot so much more (and I even added a new section to my archives for crockpot and pressure cooker recipes!)
Glad you liked the soup too!
- November 20, 2008 at 10:33 AM
- Wanita said...
This sounds delicious - can't wait to try it.
Also had to let you know that the pumpkin lattes are wonderful! I gave the recipe to my daughter. She made it for her Bible study group and also took some to work. It was a hit!
- November 20, 2008 at 11:19 AM
Thanks for another great recipe. I, too, loved the pumpkin latte recipe and am now addicted to it! WHEN do we get the chocolate peppermint mocha recipe that was listed as coming soon on your Thanksgiving list? I want it NOW (ala Violet from the original Willie Wonka movie.)
Thanks for all you do. I am a crockpot 365 evangelist. :-)
- November 20, 2008 at 12:22 PM
- MamaChristy said...
looks so yummy! We use uncooked wild rice, right?
- November 20, 2008 at 12:30 PM
- mom2nji said...
I am so excited to make this the weekend after Thanksgiving! I love the flavors. I also totally love your blog, I tell everyone about it.
- November 20, 2008 at 2:54 PM
- Lynn said...
This will be great for my leftover turkey and we love wild rice.
I believe there is some magical curative power to turkey or chicken soup that helps you get over colds faster too !
- November 20, 2008 at 4:54 PM
- Erik said...
This is so exactly the way to make this soup! I wish I had the time to make a 1 1/2 day soup, but it only happens on long weekends.
And I love wild rice with turkey!
- November 20, 2008 at 4:57 PM
Cabbage! Engorgement! Oh my stars, I have laughed until I cried. Just not at all what I was expecting in a recipe, but it sure took me back to those stupefying days of nursing a newborn. Thanks not only for the recipe but for laugh, as well.
- November 20, 2008 at 6:48 PM
as i sit here hitting 'refresh, refresh, refresh' over and over for today's pot...I wonder 'what the HELL am i gonna do NEXT year??????' I am absolutely addicted to this now.
I only found you a couple weeks ago...it seems so like a summer lovin' kinda thing. :)
- November 21, 2008 at 6:26 AM
- zan said...
Sounds wonderful, although I will probably substitute Kale or Collard Greens for the spinach, since they don't turn to mush when cooked for a long time.
- November 21, 2008 at 7:09 AM
- Jeannette said...
MMMMmmmm! This looks delicious!
- November 22, 2008 at 9:41 AM
Just got finished eating my second bowl of this for dinner. This was SOOO good! I had never used wild rice in a soup before - I love how it cooked all day long with the rest of the soup. Thank you so muchf or this great recipe!
- November 22, 2008 at 4:00 PM
- ProMom said...
My name is Brenda, and I'm a crock pot addict. Just found your blog! I'll be back! Gonna make the turkey wild rice soup. Don't worry, wild rice is SUPPOSED TO look like that. It isn't supposed to be eaten when is is still crunchy sticks. Yuck! Thanks so much for your blog and recipes. Please keep it up!
- November 22, 2008 at 5:26 PM
- Jane-Jane said...
here's a thought...if you got a small turkey breast, you could use the chicken broth and cook it in the same fashion that you did the Salsa Chicken! with just my husband and I, a whole turkey is WAY to much. and the white meat is much leaner. cook all day and it will be tender and flake into the soup!
my goal this winter is to make soup at least once a week. thanks for all the GREAT recipes!
- November 26, 2008 at 3:03 PM
- Wendy said...
Question...My kids would never eat rice, but they would eat noodles. How could I substitute? This recipe is going to be perfect for all my thanksgiving leftovers:)
- November 27, 2008 at 5:19 PM
- Crockpot Lady said...
Hi Wendy,
about 30 minutes before you want to serve the soup, stir in uncooked noodles and switch to high. I usually only put in 1/2 cup of raw pasta---it really swells a lot in the crock.
- November 27, 2008 at 10:01 PM
- Wendy said...
Thanks so much Steph!! This is on my menu for Sunday:)
- November 28, 2008 at 8:00 PM
Would it be okay to use Uncle Ben's brown rice in this recipe?
- November 29, 2008 at 6:50 PM
I made this today, and would definitely recommend adding more water or broth. I am not that experienced at crock pot cooking and mine was almost dry when I came home. However, I added some more water and some salt to it and it tasted good.
- November 29, 2008 at 9:18 PM
- cmoore523 said...
I'm dying to try this recipe! A couple of questions: a) would substituting another kind of vinegar substantially change the taste? (I have cider vinegar and red wine vinegar); and b) how would using a mix of wild rice and brown rice work? Again, something I already have on hand . . .
- November 30, 2008 at 4:50 AM
- Crockpot Lady said...
Hi there! using brown rice would work fine, but it will disappear a bit on you if it's in the whole time. Rice tends to explode if in too long. I'd stir it in 2 hours before serving, if you can. Otherwise, precook some while you're assembling the soup, and stir it in when you get home for the day.
I'd go for apple cider vinegar over red wine. Red wine might be too sweet.
- November 30, 2008 at 8:29 AM
- em said...
Hi! I just found your blog the other day. I love my crockpots! I have two, which I felt guilty to justify, until I saw your blog! LOL
I made this soup last night. I made two substitutions and an "unsubstitution", and it came out beautifully.
I used cabbage as the original recipe calls for, since its what I had on hand.
I used short grain brown rice, adding it at the beginning, and it was just fine. It was a bit mushy, but I expect that in soups.
I also used red wine vinegar instead of balsamic. It gave just that hint of tanginess that I was looking for. Very tasty!
I love that I was able to use all of my Thanksgiving turkey this year. We bought a large turkey just so that we can have leftovers for additional recipes!
Thank you so much for this blog!
- November 30, 2008 at 2:45 PM
I made this soup tonight- cold, rainy and bone chilling November night in Pittsburgh. I used my
(woefully) overcooked, leftover Thanksgiving turkey. It was unsuited for anything but soup! Soup was delicious. Also- try the pasta fagioli (0ctober recipe) it was a really big hit. Love your blog. Such a wide range of ideas. I'll admit that I'm a soup/stew person when it comes to the slow cooker. Anxious to try the granola recipe to move beyond my "comfort zone".
- November 30, 2008 at 3:37 PM
- Dianna said...
Thank you for helping me feel like a real cook this past weekend! My oven cooked turkey turned out great but my favorite part was sticking the carcass in the CrockPot Thursday night with the veggies and waking up to the most delicious smell EVER! Then on Saturday, I put together this soup and it was awesome! Unfortunately, I couldn't get my sick husband or picky kids to join in my enthusiasm so I wanted to share with you! I love your blog. I just recently found it and have found renewed motivation in the kitchen. I was definitely in a cooking slump! I am looking forward to trying all of the recipes that I am behind on!
- December 1, 2008 at 6:15 AM
I cook GF for my husband. A friend just told me about this blog. Crockpot Lady you are my new BFF :) I can't wait to try this recipe and many other GF ones. Thank you!!!!
- December 2, 2008 at 7:59 PM
- David said...
I am in a dinner club where every week we each take turns making dinner for the other families.
I made this recipe (with frozen turkey from Christmas!) and it was really unbelievable! I questioned that it did not have much seasoning, but the flavors were dynamite! I can't wait to hear how my friends liked it!
thanks so much!!!
- February 27, 2009 at 12:14 PM
I've got a turkey, all right, only I'm married to him.
- April 9, 2009 at 1:41 PM
- NJD said...
I just made this again yesterday for my dinner club! So yummy!!
- November 12, 2009 at 6:13 AM
I made your recipe with alternate ingredients. I had a Pheasant from a hunting trip this week, so I was looking for a good recipe to combine the pheasant with some wild rice that a friend from Minnesota had given me. I made some slices across the breast meat and cooked down the whole bird, some onion, celery, and carrots. I added a cup or so of crimini mushrooms. I rinsed and added the rice, spinach, some BokChoy, and mushrooms a couple hours into the cooking process but the rice still got mushy. Guess next time I will do like I do when making other soups with rice and add it in the last hour or so. We did leave for the afternoon, so you can still go out while this is cooking. Oh, I did have to add some salt and pepper, but the amount is up to the individual.
- December 13, 2009 at 4:01 PM
- kati said...
and i thought i was the only one who used cabbage for engorgement, lol!! i'm loving your blog and can't believe i've missed it all these years :( tried the apple coffee cake tonight and i will never again be able to make a single recipe as my family attacked it like ravished wolves. your blog is awesome and you are hilarious!! ~Kati :)
- May 18, 2011 at 10:50 PM
- Quiltin' Jenny said...
I can't wait to try this recipe (once it gets cooler) as we are working on less gluten in our diet, among other things. Nothing on the "NO" list is in this recipe - hooray!
Sounds like this makes a lot. Have you tried freezing it? I'm always looking for recipes that freeze well. I may try it with a small amount just to see.
Thanks for all your great recipes and inspirations!
- August 2, 2011 at 11:27 AM
- Sue KuKu said...
I just made this soup and gave to my church organist -- his wife is on severe medication which makes her nauseated.
I thought this soup would be good for her.
I cut the recipe in half for my 3 quart crock pot. I had a small bowl of it before I gave them the rest. Hey, I had to try it out! Julia Child always said that! =O)
Now I need to make a pot for myself, as I have more than enough leftover ingredients to make another pot. Oh darn!
- October 7, 2011 at 8:56 AM
- Jules said...
Can't wait to try this recipe today! And by the way, we're reading "On The Banks of Plum Creek" right now (to my two BOYS who love it!), so it's still summertime where we are! :) haha!
- November 25, 2011 at 5:19 AM
Well, the turkey is in the crockpot, and hate to wish the day away, but can't wait to taste it!
Happy to see folks reading Laura Ingalls Wilder books! My husband's grandfather was
"Banker Ruth" in The Long Winter, and lived a couple of doors down from the Ingalls family in DeSmet, SD. His home has been restored and is now a B&B.
- November 26, 2011 at 10:30 AM
- 3T Mama said...
Just finished making the broth over night with the carcass and it smells wonderful. Can't wait for dinner tonight.
- November 27, 2011 at 7:23 AM
- Cee Jay Kay said...
I adore Kalyn. It was through her site that I found you for the Mashed Potato recipe. I'm on the South Beach diet for life and am gluten intolerant, which is why I looked for a turkey and rice soup instead of one with noodles. We are fortunate that this time of year in Florida we have greens in the yard. We added kale instead of spinach. It was AWESOME. I won't say this is on my rotation list, but it is definitely on my list for what to do with turkey next time we roast it. By the way, I am now up from one crock pot to five, ranging in all different sizes. Who would have thunk it.
- November 29, 2011 at 5:13 PM
- debrussell said...
Oh my gosh! This soup was amazing and I'm not much of a soup lover. I wasn't sure about the balsamic vinegar, but after eating the soup, I totally get it. My family absolutely loved it. Thank you so much!
- November 29, 2011 at 7:43 PM
- Atwood-Family of FIVE said...
This soup was VERY tasty! Even hubby who isn't the biggest fan of soups really liked this one!
- December 5, 2011 at 8:33 PM
Ok. Turkey wings were on sale and I bought two instead of buying cooked turkey (didn't have a carcass eithier). I'm going to wing it (ha! pun intended) and throw them wings in there for as long as the soup requires and see what happens...Is it going to be a disaster??
- March 3, 2012 at 2:01 PM
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Expert witness Vytenis Babrauskas and 13th Judicial Circuit Solicitor Walt Wilkins enjoy a brief laugh after lengthy and sometimes heated testimony in preparation for the trial of Don Kinsela, who is charged with arson and murder.
Defense attorney Druanne White questions expert witness David Icove, who sharply criticized a fire investigation which concluded that a 2010 Easley fire was an arson.
Defense attorney Trevor White and Don Kinsela, right, watch as experts testify during pre-trial motions at a Pickens County courtroom Tuesday.
Walt Wilkins, 13th Judicial Circuit solicitor, uses a drawing of an outbuilding where Cheryl Kinsela died in 2010 during questioning Tuesday in preparation for the trial of Kinsela's husband, who is charged with murder and arson.
Don Kinsela talks to a family member during a break in the Tuesday pre-trial motions as Kinsela goes into a trial today for charges of murder and arson.
Don Kinsela walks around during a break in pretrial motions Tuesday in preparation for his trial on charges of murder and arson. The charges were filed after his wife died in a fire at an outbuilding on their Easley property in 2010.


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Legacy of a Trident Scholar
Posted on: June 04, 2013 08:00 EDT by LT Teng K. Ooi and CAPT Linda J. Beltra
The Naval Academy Mathematics Department is honored to receive personal papers including books, photographs and other memorabilia of one of the USNA's most successful Trident Scholars Adm. Donald Lee Pilling.
The items were donated by his widow, Mrs. Barbara Pilling, in a dedication ceremony held April 23 in Chauvenet Hall.
The Naval Academy established the Trident Scholar Program in 1963 to provide an exciting opportunity to a select number of exceptional midshipmen to pursue independent study and research during their senior year. The program pairs each Trident Scholar with an assigned faculty adviser and other area specialists to coordinate and supervise a research project. At the end of the academic year, the Trident Scholars present their findings at a research talk hosted at the Naval Academy. The most outstanding research project is awarded the Office of Naval Intelligence Harry E. Ward Trident Scholar Prize.
A 1965 graduate of the U.S. Naval Academy, Pilling graduated 4th in his Naval Academy class and was one of the first Trident Scholars. His Trident Scholar project, "Distributivity and Completeness in Implication Algebra," involved the study of partially ordered systems. Under the direction of his adviser, the late Dr. James C. Abbott, Naval Academy Mathematics Department, Pilling won the Harry E. Ward Trident Scholar Prize.
Pilling went on to earn a Ph.D. in mathematics from the University of Cambridge, United Kingdom in 1970 with a dissertation, "The Algebra of Operators for Regular Events," under Dr. John H. Conway, University of Cambridge. He enjoyed a distinguished naval career culminating with a tour as the Navy's 30th Vice Chief of Naval Operations.
Pilling passed away on May 26, 2008 and rests on top of a hill at the Naval Academy Cemetery, overlooking the scenic Annapolis Harbor.
The Mathematics Department is truly excited to add this collection of Pilling's personal papers to the library's holdings of materials that continue to motivate, inspire and guide midshipmen. The papers will be immensely valuable to contemporary scholars including faculty, staff and midshipmen, who will have the opportunity to study these documents and use them to supplement their studies of defense acquisition, national security issues, and foreign policy implications for future naval forces. Readers will gain an insight into Pilling's decision making, logical reasoning, and methodical thinking process as well as his legendary intelligence and wit.
Mrs. Barbara Pilling (right) at the dedication ceremony attended by members of the Naval Academy class of 1965, the Mathematics Department faculty members and midshipmen. Courtesy photo by LT Teng Ooi.


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Intermediary liability and the future of the Internet in India
"Intermediary liability" may sound like something you'd only hear about in a law school torts class, but its meaning is both important and easy for all Internet users to understand.
It's the principle that Internet middlemen -- like ISPs, website hosting companies, search engines, email services, social networks, and other neutral hosts of information sent, posted or uploaded by others -- should not be held legally liable for their users' content. Put another way, it's the principle that the person who created the content is the person deemed responsible for it, and that it would be both unjust and impractical to hold companies whose systems happen to automatically transmit or store the content responsible for words they didn't write, pictures they didn't take, or videos they didn't create.
Still puzzled? Think about the telephone system. We don't hold the telephone company liable when two callers use the phone lines to plan a crime. For the same reasons, it's a fundamental principle of the Internet that you don't blame the neutral intermediaries for the actions of their customers. Rather, the standard recognized worldwide is that Internet intermediaries are responsible to take action when they are put on notice of unlawful content through proper legal channels.
This principle has been the subject of much recent debate as India takes a fresh look at its technology laws.
The government of India is looking to amend the Information Technology Act of 2000, the law which governs the web. As I've written before, the Department of Information Technology's proposed amendment to Section 79 of the IT Act would mark a fundamental shift in Indian law as it relates to intermediary liability, and go a long way towards promoting innovation on the Internet.
Under the proposed amendment, intermediaries like Google would not be held responsible for problematic content on their systems that they did not create. Instead, intermediaries would be protected so long as they follow appropriate lawful process after being notified of the content in question (in the copyright context, this is known a "notice-and-takedown" regime). This principle has been embraced in all the leading democracies of the world.
Unfortunately, last month the Indian Parliament's Standing Committee on Information Technology issued its own report challenging this proposed amendment:
While we thank the Committee for its hard work and thoughtful deliberations, we're troubled by this tone and line of thinking. If implemented, these recommendations would create a hostile environment in India for Internet services, and for the entrepreneurs and innovators working to create the next set of revolutionary Internet technologies for Indian users.
For intermediary websites to be held liable for the "reckless activities" of others is fundamentally unjust, ignores the origin of the content, misunderstands the size and scale of the Internet, and fails to appreciate the great benefits yielded to the vast majority of Indian users by these information platforms.
At Google we take issues like cybercrime, the transmission of illegal content, and its harm on victims very seriously. We work with government authorities to ensure Google's platforms in India are not used illegally and that they are in full compliance with our own terms and conditions. We also work diligently to ensure our own community standards (like orkut's, for example) are not violated on our sites.
It would be technologically infeasible for ISPs and web companies to pre-screen each and every bit of content being uploaded onto our platforms, especially as the amount of information coming online increases exponentially in India and around the world. More importantly, imposing such a burdensome standard would crush innovation, throttle Indian competitiveness, and prevent entrepreneurs from deploying new services in the first place, a truly unfortunate outcome for the growth of the Internet in India.
It is possible that this portion of the Committee's report is based on a misapprehension of the intent of the proposed amendment. Specifically, the Committee may have believed that the proposed amendment would provide absolute immunity to Internet intermediaries, and wished to stress the need for a clear obligation to react promptly when put on notice of unlawful content. If this was, in fact, the case, the Committee's intent, its report would be consistent with the proposed amendment, and in line with global best practices. If not, the Committee's position would likely result in the hobbling of the Internet in India. For that reason, we intend to seek clarification of the Committee's understandings and intent.
The choice for the Indian government is stark: If it wishes to enable Indians to have access to cutting-edge Internet services, and to promote innovation on the Internet, the Department of Information Technology should uphold the principle of qualified safe harbors for Internet intermediaries.
20 comments:
well said... but god only knows when those decision making babu's would realize it...ReplyDelete
This is usual oneside crying of ISPs, who does not want to be governed by regulations. Internet is bound to grow, whether google likes it or not. If google is unhappy and would like to quit/downscale, some one else will come.ReplyDelete
What is the harm in "due diligence" being in main act against desired in guidelines, as said by MoIT. ISPs talk of self-regulation, which the committee rightly said as eye-wash. No self-regulation works anywhere, at least in India.
Further, Internet is much more than Telephone / Postal services, as anology given by ISPs. You can not compare apples and oranges.
Thanks to Mr. Rishi Jaitly for justifying his job as part of google team.
Rakesh Goyal
The recommendations made by the Parliamentary committee are largely sensible and reverses the motivated amendments suggested by the Minstry earlier.ReplyDelete
The Parliamentary committee deserves a strong appreciation for its efforts and recommendations.
Detailed comments are available at http://www.naavi.org on the mis conceptions created by the recent Times of India article.
Kindly make this part of the page display in English.ReplyDelete
This is intelligebile to a large section of population in India.
Interesting comments about the telephone system in India.ReplyDelete
Maybe they should consider a PBX Phone System because it offers cost savings on internal phone calls.
ペアリング リッジリングにドイツリングを選ぶ。それは一生涯を共にするのに相応しい価値ある逸品。 ドイツリング専門店ヘルディンヘルト">
出会い系出会い系サイトトラブル対処法! 大人なら引っかかりたくない出会い系サイトのトラブル対処法を紹介します。
ショッピング枠 現金化ショッピング枠 現金化
Hi Rishi. I would like to contact you regarding a consultative meeting we are organising in Mumbai in Sept. on the role of internet cos. in helping to stop sex selection. May i have your email id or can we speak sometime? My cell no. is 0 98200 10052 and email id is: firstname.lastname@example.com
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As for WoW, they shouldn't be allowed to get away with it either. Kill quotas are par for F2P games and people should be holding P2P games to a much higher standard then that. But at least once you hit 80 you stop questing and start running instances. I guess it's a start...
Last edited by Bacn; 08-27-2009 at 11:44 PM.
Couldn't Take It No More
So I Became Hardcore
Sure the majority of the quests are kinda generic, but there's a few quests that stand out.
Fight club and a few other quests come to mind.... Though I've been hearing that the quests get better once you're over level 25. I've personally kept to a low level so I don't burn out the content, but high enough to try out some of the powers I thought were cool.
Actually, I'd say at least half of the CO missions are far more interesting than "KILL X" missions. I actually get very few missions like that.
And the Nemesis missions are AMAZING.


text: Visionary designer Giorgio Armani's two-story farmhouse, located a block from the sea on the Versilia coast of Italy, was thoroughly renovated 20 years ago but chose not to alter the rustic exterior. The living room narrows at one end to an intimate fireside sitting area. White panels on the walls and ceiling lend the room a nautical air. The house, shown in Architectural Digest in May 1983, is "ideal for a simple, ultrarelaxing holiday shared with friends," says Armani. (December 2004)Photo: Jaime Ardiles-ArcePinterestFacebook


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