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History of Amyloid Deposition in Adults With Down Syndrome
Recruitment status was Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The impact of a significant number of adults with Down syndrome developing Alzheimer's disease in their middle and later years is considerable in terms of the burden to family and caretakers, the effect on quality of life for the individual, as well as the costs for providing medical care. Consequently, identification of the nature, cause and outcome of decreased cognitive performance in adult Down syndrome individuals will be an essential component to improving the quality of life of this population.
Down Syndrome
Amyloid Deposition
Alzheimers Disease
|Study Type:
|Study Design:
|Time Perspective: Prospective
|Official Title:
|Natural History of Amyloid Deposition in Adults With Down Syndrome
- Assessing presence of amyloid in functionally stable adults with DS [ Time Frame: Years 1 and 2 all participants will have brain function measures assessed during 2 visits to the site which may be consecutively or at convenience of participant. This conclude participant's participation in this study. ] [ Designated as safety issue: No ]The primary objective of this proposal is to assess the presence of amyloid in non-demented/functionally stable adults with DS as a function of age, dividing the sample into amyloid-positive and amyloid-negative groups. We will also obtain baseline cognitive measures across a range of areas that are often affected by AD.
|Estimated Enrollment:
|Study Start Date:
|December 2010
|Estimated Study Completion Date:
|December 2012
|Estimated Primary Completion Date:
|August 2012 (Final data collection date for primary outcome measure)
Cohort 1 Adults with DS
Adults ages 30 to over 50 years of age
Detailed Description:
Our research group at the University of Pittsburgh has recently developed a promising, non-invasive, in vivo PET tracer for imaging amyloid deposition in living humans. Known as Pittsburgh Compound-B (PiB), it has shown much promise in documenting pre-symptomatic amyloid deposition in living subjects destined to develop Alzheimer's disease (AD). PiB also provides a means to determine the natural history of amyloid deposition. While there has been increasing use of PiB to assess amyloid deposition in cognitively normal individuals, the fact remains that despite identifiable risk factors that increase the likelihood of acquiring AD (e.g., age, family history, ApoE4), we cannot identify with certainty those who will develop AD. This makes the study of pre-clinical amyloid deposition difficult in the general population. Conversely, individuals with Down syndrome (DS) are at high risk for developing AD due to the presence of an extra copy of chromosome 21, which codes for the Ab precursor protein (APP) gene. Post-mortem studies have documented the presence of AD pathology in 60 to 90% of adults with DS (with greater pathology increasing with age)(Additionally, symptoms of AD occur in over 40% for DS individuals between 50 and 59 years of age. Thus, the study of adults with DS provides a valuable opportunity to follow the natural history of amyloid deposition and compare it to clinical symptomatology - knowing that approximately half of the group will eventually develop clinical AD and an even greater fraction will develop amyloid deposits. Toward that end, the current multi-center proposal (University of Pittsburgh and University of Wisconsin) will document amyloid deposition in 64 non-demented/functionally stable adults with DS over a two-year period. We will study three age cohorts: 30-39 yrs, 40-49 yrs and >50 yrs. Subjects will also be assessed for the presence of the apolipoprotein-E4 (ApoE4) allele to determine its possible association with accelerated deposition brain amyloid. While we will not complete a natural history study of amyloid deposition in DS during the current project period, this effort will lay the foundation by gathering a valuable cohort of PiB+, non-demented DS subjects that we can follow beyond this grant period with future funding.
|Ages Eligible for Study:
|30 Years to 80 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
Adults ages 30 to over 50 years of age diagnosed with Down Syndrome
Inclusion Criteria:
- Adults with Down Syndrome over the age of 30 years.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01412255
|Contact: Benjamin L Handen, PhD
|Contact: David Maloney, BA
|United States, Pennsylvania
|University of Pittsburgh Medical Center
|Pittsburgh, Pennsylvania, United States, 15213
|Contact: Benjamind L Handen, PhD 412-235-5445 firstname.lastname@example.com
|Contact: David Maloney, BA 412-235-5407 firstname.lastname@example.com
|Principal Investigator: Benjamin L Handen, PhD
No publications provided
|Responsible Party:
|Benjamin L. Handen, PhD, University of Pittsburgh
|ClinicalTrials.gov Identifier:
|NCT01412255 History of Changes
|Other Study ID Numbers:
|Study First Received:
|August 2, 2011
|Last Updated:
|August 5, 2011
|Health Authority:
|United States: Federal Government
Keywords provided by University of Pittsburgh:
Amyloid Deposition
Down Syndrome
Alzheimer's Disease
Additional relevant MeSH terms:
Alzheimer Disease
Down Syndrome
Abnormalities, Multiple
Brain Diseases
Central Nervous System Diseases
Chromosome Disorders
Congenital Abnormalities
Delirium, Dementia, Amnestic, Cognitive Disorders
Genetic Diseases, Inborn
Intellectual Disability
Mental Disorders
Nervous System Diseases
Neurobehavioral Manifestations
Neurodegenerative Diseases
Neurologic Manifestations
Pathologic Processes
ClinicalTrials.gov processed this record on October 09, 2015


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Keith Warner is one of the leading directors of our time. He was Co-Director at English National Opera in London, Scottish Opera and Artistic Director of Opera Omaha in Nebraska. He has directed more than 100 operas, musicals and plays all over the world. Highlights to date have included John Casken's God's Liar (world premiere) in London and Golem (US premiere), Lohengrin in Bayreuth, The Turn of the Screw in Brussels and Ring productions in Tokyo and London (Covent Garden). His most recent productions were Tannhäuser in Strassbourg, Mathis der Maler in Vienna, Andrea Chénier in Bregenz, the world premiere of André Tchaikovsky's Der Kaufmann von Venedig/The Merchant of Venice, Parsifal in Copenhagen, Penderecki's Die Teufel von Loudun/The Devil from Loudun in Warsaw and Chausson's Le Roi Arthus/King Arthur at the Théâtre Municipal in Strassbourg. Projects in 2015 include Richard Ayres' Peter Pan at the Wales Millennium Centre in Cardiff (conducted by Erik Nielsen).
He has directed many highly successful productions at Oper Frankfurt over the last decade, including Rossini's Cenerentola (revival opens April 11th 2015!), a double bill of Dallapiccola's Volo di notte and Il prigioniero, Bloch's Macbeth, Britten's Death in Venice and, more recently, Thomas Adès' The Tempest (first ever performances in Germany), Reimann's Lear and Pizzetti's Murder in the Cathedral (revival opens April 18th 2015!). Now he is back for this new production of Hänsel und Gretel. Keith Warner won an Olivier Award for his 2003 production of Wozzeck at Covent Garden.
- Season Calendar
- New Productions 2015/2016
- Revivals 2015/2016
- Recitals 2015/2016
- Concerts 2015/2016
- Opera for You 2015/16 events for children, young people and families
- Special Events 2015/2016
- Cast Changes
- Ensemble, guest artists and the Opera Team
- The orchestra
- Opera Studio
- Videos
- Press Releases
- Series of Live Recordings made at Oper Frankfurt

subset: commoncrawl


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BEST ENTRANCE: From the parking deck between Macy*s & Nordstrom, use the upper level mall entrance near La Bottega
LOCATION IN MALL: Located on the upper level between Nordstrom and Macy's.
(516) 248-7200
Then Get Our Can't Miss Style Reports, Retailer
Offers and Event News Before Everyone Else.
Plus you'll be entered to win a $1,000 Shopping Spree.


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The Lyric Feature is RTÉ lyric fm's weekly documentary and music feature programme. Programmes are produced in house by Lyric fm staff or in collaboration with independent production companies. Subject matter varies from week to week but most of the programmes aim to provide insight into music and music making.
The Lyric Feature is currently accepting proposals from independent producers and production companies for the BAI's Sound and Vision III Round 24. See here for details
Tip: You can drag and scroll the programme grid with your mouse


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(NEWS CENTER) - Maine Secretary of State Charlie Summers is embarking on a tour to open a discussion about driver safety among young adults.
Summers says in 2011, there were around 50 deadly crashes involving a driver between the ages of 16 and 24.
He says it's his responsibility to improve the safety of young drivers and all people traveling Maine's roadways.
Secretary Summers has established a special panel that will review young driver requirements, including laws, rules and the driver education curriculum in Maine.
Summers and the Panel will be holding "Coversations with the Communities" at Bureau of Motor Vehicle offices across the state this January.
Dates & Times:


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The official SevenStock event page
SevenStock turns 18!! For the 18th straight year, the hardworking volunteers of The SoCal RX Club are hosting The Greatest RE Festival in the World. Building on the continued success of previous years, this SevenStock promises to be great yet again!
Join us November 7th, 2015 as the RE family is treated to Mazda North America's historic Race Cars on display AND run at full speed on the legendary Auto Club Speedway.


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|Martin Named SoCon Specialist Of Week
|Written by Jason Yaman
|Monday, 15 October 2012 10:42
The Southern Conference named its football players of the week today for games played Saturday, Oct. 13. Georgia Southern's Dominique Swope has been named the Offensive Player
of the Week, while Western Carolina's Rock Williams was named the Defensive Player of the Week. Chattanooga's Jacob Huesman was selected as the Freshman of the Week, while Appalachian State's Sam Martin was tabbed the Special Teams Player of the Week. The players of the week are selected by the conference office.
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#TCWeather: Some clouds but no rain Friday
Temperatures will climb into the 80s by early this afternoon, but today will be a little warmer than Thursday, with low to mid 80s along the coast and some upper 80s possible inland.
Skies will be mostly to partly sunny and there will be a light breeze out of the southeast.
Today, expect a high near 82 and a southeast wind of 5 to 10 mph increasing to 10 to 15 mph in the afternoon. Winds could gust as high as 25 mph, according to the National Weather Service.
Tonight, the forecast calls for patchy inland fog and partly cloudy skies. Lows will be in the mid to upper 60s and light winds out of the south.
Tonight will see a low around 65 and a southeast wind of 5 to 10 mph, the Weather Service states.
Sunset is at 7:39 p.m.
Keep an eye on conditions with our live weather radar and full weather report.
Let us watch the weather radar for you. "Like" us on Facebook or follow #TCweather on Twitter for posts giving you a heads up on weather worth noting.
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Enlarge / Alternate Images
Every Body Needs A Thera-Loop
Every patient who receives resistance tubing and banding needs a place to exercise at home. Thera-Loop makes it easy by turning nearly any doorway into a place to do exercises and the loop can be easily moved to the right height for each exercise. That's because the simple webbing-strap Thera-Loop, sprayed at the door end with a non-slip material, resists sliding up and down when it is placed in the hinge side of a closed and latched door.
Height adjustments are limitless. Thera-Loop helps you educate the patient about where, and at what height, to start and end resistance exercise. Tying off on a door knob or a furniture leg can be dangerous and unproductive. Everyone has experienced horror stories about the tubing or banding that slipped off its anchor and painfully struck the patient. Thera-Loop solves that problem.
This simple device, invented by a home therapist, can help increase patient compliance. It also protects against damage to tubing and banding that results from repeatedly closing it into door frames unprotected.
Available in eaches (841 1005), 10 and 50 packs (841-0203).
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People like to drink beer!
stubby wrote:If it seems weird to have alcohol at the office, then this place is weird 24/7. The lone bottle of Maker's on my desk gives me the unfortunate distinction of having the desk bearing the least alcohol in the whole department.
Edit: Never mind, I also have a bottle of Bushmill's I forgot about, hiding behind an LU poster. That makes me tied with the 3D guy's gin supply for last place.
Arkbrik wrote:My personal opinion is that both Xbox and PS suck, and you should get a life or download Nethack.
booty bothered wrote:OMFG THATS WHERE MY BUSHMILLS WENT
Users browsing this forum: No registered users and 2 guests


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Start a new thread under an appropriate topic on the ethernet issue.
Look in /var/log/messages for the exact error you are getting. Post it along with details on your hardware and your network setup.
We'll fix that and go from there.
Jim H
P.S. Might want to check out this thread.


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Jason Williamson, an Elite Series Pro, worked with Buckeye Lures to create the new the Buckeye Lures Light Wire J-Will Swimbait Heads. Perfect for smaller swimbaits and fishing with umbrella rigs, the Buckeye Lures J-Will Light Wire Swimbait Heads feature light wire, super sharp Mustad hooks for faster penetration and unmatched strength. The Buckeye Lures Light Wire J-Will Swimbait Heads have also been custom painted to match most colors of swimbaits on the market, and the collar on the head holds your swimbait securely cast after cast.
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Comments: Great hooks but COME ON WITH THE RIDICULOUS PRICING OF $5.59 for only 3 HOOKS!!!! Really! Buckeye would make MORE $$$ if they will lower the price so people will buy....
From: Larry: ATL, GA
***Note: If you have questions about this product or need assistance with an order please email your questions to email@example.com


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Busan International Film Festival - Day 1
Actress Eum Ji-Won arrives for the opening ceremony of the 16th Busan... News PhotoActress,Arrival,Arts Culture and Entertainment,Award,Busan,Ceremony,Film,Film Festival,Film Industry,Opening Ceremony,South Korea,VerticalPhotographer Chung Sung-JunCollection: Getty Images Entertainment 2011 Getty ImagesBUSAN, SOUTH KOREA - OCTOBER 06: Actress Eum Ji-Won arrives for the opening ceremony of the 16th Busan International Film Festival (BIFF) at the Busan Cinema Center on October 6, 2011 in Busan, South Korea. The biggest film festival in Asia showcases 307 films from 70 countries and runs from October 6-14. (Photo by Chung Sung-Jun/Getty Images)


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I have zero experience in regards to formally writing a script, so this is just my attempt at writing some sort... : Literary Fiction » Read
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Vibram FiveFingers
Spyridon (Men's)
Out of Stock Product Number: 33589
The Spyridon offers the same great minimalist trail running experience as the Spyridon LS providing the perfect balance of "foot feel" and protection on rugged terrain. With Vibram's 3D Cocoon technology, the Spyridon has a multidirectional sole, which allows for impact protection from stones and debris with minimal weight. The Coconut Active Carbon upper breathes naturally using 34% post industrial coconut fiber. It is finished off with an adjustable hook-and-loop closure ensuring a secure fit and reflective applications for safety after dark. Machine Washable. Air Dry.
* This product does not qualify for shipping to all countries.
3mm Polyurethane Insole Anti-Microbial Dri-Lex Sockliner footbed
Gender: Men's
Weight: Men's 44: 6.88 oz. each
Shoe Upper: Stretch Mesh and Polyamide
Shoe Lining: Anti-Microbial Dri-Lex Sockliner
Shoe Sole: XSTrek Vibram Rubber
Season: S13
Vendor ProductId: M4553
Review ProductId: 33589


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prev | next
(a) Prohibition against discrimination; exceptions
No person in the United States shall, on the basis of sex, be excluded from participation in, be denied the benefits of, or be subjected to discrimination under any education program or activity receiving Federal financial assistance, except that:
(1) Classes of educational institutions subject to prohibition
in regard to admissions to educational institutions, this section shall apply only to institutions of vocational education, professional education, and graduate higher education, and to public institutions of undergraduate higher education;
(2) Educational institutions commencing planned change in admissions
in regard to admissions to educational institutions, this section shall not apply
(A) for one year from June 23, 1972, nor for six years after June 23, 1972, in the case of an educational institution which has begun the process of changing from being an institution which admits only students of one sex to being an institution which admits students of both sexes, but only if it is carrying out a plan for such a change which is approved by the Secretary of Education or
(B) for seven years from the date an educational institution begins the process of changing from being an institution which admits only students of only one sex to being an institution which admits students of both sexes, but only if it is carrying out a plan for such a change which is approved by the Secretary of Education, whichever is the later;
(3) Educational institutions of religious organizations with contrary religious tenets
this section shall not apply to an educational institution which is controlled by a religious organization if the application of this subsection would not be consistent with the religious tenets of such organization;
(4) Educational institutions training individuals for military services or merchant marine
this section shall not apply to an educational institution whose primary purpose is the training of individuals for the military services of the United States, or the merchant marine;
(5) Public educational institutions with traditional and continuing admissions policy
in regard to admissions this section shall not apply to any public institution of undergraduate higher education which is an institution that traditionally and continually from its establishment has had a policy of admitting only students of one sex;
(6) Social fraternities or sororities; voluntary youth service organizations
this section shall not apply to membership practices—
(A) of a social fraternity or social sorority which is exempt from taxation under section 501 (a) of title 26, the active membership of which consists primarily of students in attendance at an institution of higher education, or
(B) of the Young Men's Christian Association, Young Women's Christian Association, Girl Scouts, Boy Scouts, Camp Fire Girls, and voluntary youth service organizations which are so exempt, the membership of which has traditionally been limited to persons of one sex and principally to persons of less than nineteen years of age;
(7) Boy or Girl conferences
this section shall not apply to—
(A) any program or activity of the American Legion undertaken in connection with the organization or operation of any Boys State conference, Boys Nation conference, Girls State conference, or Girls Nation conference; or
(8) Father-son or mother-daughter activities at educational institutions
this section shall not preclude father-son or mother-daughter activities at an educational institution, but if such activities are provided for students of one sex, opportunities for reasonably comparable activities shall be provided for students of the other sex; and
(9) Institution of higher education scholarship awards in "beauty" pageants
this section shall not apply with respect to any scholarship or other financial assistance awarded by an institution of higher education to any individual because such individual has received such award in any pageant in which the attainment of such award is based upon a combination of factors related to the personal appearance, poise, and talent of such individual and in which participation is limited to individuals of one sex only, so long as such pageant is in compliance with other nondiscrimination provisions of Federal law.
(b) Preferential or disparate treatment because of imbalance in participation or receipt of Federal benefits; statistical evidence of imbalance
Nothing contained in subsection (a) of this section shall be interpreted to require any educational institution to grant preferential or disparate treatment to the members of one sex on account of an imbalance which may exist with respect to the total number or percentage of persons of that sex participating in or receiving the benefits of any federally supported program or activity, in comparison with the total number or percentage of persons of that sex in any community, State, section, or other area: Provided, That this subsection shall not be construed to prevent the consideration in any hearing or proceeding under this chapter of statistical evidence tending to show that such an imbalance exists with respect to the participation in, or receipt of the benefits of, any such program or activity by the members of one sex.
(c) "Educational institution" defined
For purposes of this chapter an educational institution means any public or private preschool, elementary, or secondary school, or any institution of vocational, professional, or higher education, except that in the case of an educational institution composed of more than one school, college, or department which are administratively separate units, such term means each such school, college, or department.
Source(Pub. L. 92–318, title IX, § 901,June 23, 1972, 86 Stat. 373; Pub. L. 93–568, § 3(a),Dec. 31, 1974, 88 Stat. 1862; Pub. L. 94–482, title IV, § 412(a),Oct. 12, 1976, 90 Stat. 2234; Pub. L. 96–88, title III, § 301(a)(1), title V, § 507,Oct. 17, 1979, 93 Stat. 677, 692; Pub. L. 99–514, § 2,Oct. 22, 1986, 100 Stat. 2095.)
References in Text
This chapter, referred to in subsecs. (b) and (c), was in the original "this title", meaning title IX of Pub. L. 92–318which enacted this chapter and amended sections 203 and 213 of Title 29, Labor, and sections 2000c, 2000c–6, 2000c–9, and 2000h–2 of Title 42, The Public Health and Welfare. For complete classification of title IX to the Code, see Short Title note below and Tables.
1986—Subsec. (a)(6)(A). Pub. L. 99–514substituted "Internal Revenue Code of 1986" for "Internal Revenue Code of 1954", which for purposes of codification was translated as "title 26" thus requiring no change in text.
1976—Subsec. (a)(6) to (9). Pub. L. 94–482substituted "this" for "This" in par. (6) and added pars. (7) to (9).
1974—Subsec. (a)(6). Pub. L. 93–568added par. (6).
Effective Date of 1976 Amendment
Pub. L. 94–482, title IV, § 412(b),Oct. 12, 1976, 90 Stat. 2234, provided that: "The amendment made by subsection (a) [amending this section] shall take effect upon the date of enactment of this Act [Oct. 12, 1976]."
Effective Date of 1974 Amendment
Pub. L. 93–568, § 3(b),Dec. 31, 1974, 88 Stat. 1862, provided that: "The provisions of the amendment made by subsection (a) [amending this section] shall be effective on, and retroactive to, July 1, 1972."
Short Title of 1988 Amendment
Pub. L. 100–259, § 1,Mar. 22, 1988, 102 Stat. 28, provided that: "This Act [enacting sections 1687 and 1688 of this title and section 2000d–4a of Title 42, The Public Health and Welfare, amending sections 706 and 794 of Title 29, Labor, and section 6107 of Title 42, and enacting provisions set out as notes under sections 1687 and 1688 of this title] may be cited as the 'Civil Rights Restoration Act of 1987'."
Short Title
Pub. L. 107–255, Oct. 29, 2002, 116 Stat. 1734, provided "That title IX of the Education Amendments of 1972 (20 U.S.C. 1681 et seq.; Public Law 92–318) [title IX of Pub. L. 92–318, enacting this chapter and amending sections 203 and 213 of Title 29, Labor, and sections 2000c, 2000c–6, 2000c–9, and 2000h–2 of Title 42, The Public Health and Welfare] may be cited as the 'Patsy Takemoto Mink Equal Opportunity in Education Act'."
Transfer of Functions
"Secretary" substituted for "Commissioner" in subsec. (a)(2) pursuant to sections 301(a)(1) and 507 ofPub. L. 96–88, which are classified to sections 3441 (a)(1) and 3507 of this title and which transferred functions of Commissioner of Education to Secretary of Education.
Coordination of Implementation and Enforcement of Provisions
For provisions relating to the coordination of implementation and enforcement of the provisions of this chapter by the Attorney General, see section 1–201(b) of Ex. Ord. No. 12250, Nov. 2, 1980, 45 F.R. 72995, set out under section 2000d–1 of Title 42, The Public Health and Welfare.
Regulations; Nature of Particular Sports: Intercollegiate Athletic Activities
Pub. L. 93–380, title VIII, § 844,Aug. 21, 1974, 88 Stat. 612, directed Secretary to prepare and publish, not more than 30 days after Aug. 21, 1974, proposed regulations implementing the provisions of this chapter regarding prohibition of sex discrimination in federally assisted programs, including reasonable regulations for intercollegiate athletic activities considering the nature of the particular sports.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


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Reach tens of thousands of people instantly by advertising with Ekklesia. Find out more
An ideal present for Christmas or birthdays, or just as the fulfillment of a fantasy - now you can be the manager of a real football club. The People's Club - a football club owned by the fans for the fans, means you become the joint owner of a real-life football team.


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Croc Magic Diffuser
We know you want the goods as soon as possible, which is why orders received by 3pm ET leave our warehouse the very same day. We'll send you an email that day to confirm shipment and the email will include your tracking information.
Our warehouse is closed Saturday & Sunday, so orders received after 3pm ET on Fridays will not ship out until Monday.
Based on 2 Reviews
Cindy P.MAHairMedium BrownCurly HairColor Treated HairDeva Approved !This fit perfect on my Croc dryer and did not add extra weight to disrupt the overall balance of this nice lightweight dryer. Works great for the days I want to embrace my natural curl or to dry with out frizz before a blow out. Great price and product !
Was this post helpful?YesNoposted Jan 27, 2014Link to this post
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JessicaCharlotte, NCPretty Good DiffuserThis diffuser is really cool you can turn it so that the hair only goes through the pointy things or change it so it goes through the vents. I got the Croc Greenion Dryer and it doesn't 'fit' on there. It will stay on but it doesn't snap on or anything so it makes me nervous that it will fall off and break, especially since the plastic the diffuser is made of is really thin and cheap so it will most likely break if dropped.15 out of 15 shoppers thought this review was helpful.
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Definition? Are there different definitions other than the well known definition?
What is your definition for them and what do you think about them?
Definition? Are there different definitions other than the well known definition?
To err is human, to moo bovine.
virus = hello world.
Vern, your answer is too obscure
Virus = worst nigthmare for Windows users like me.... (reason y im starting to learn *nix...)
virus ... is something that makes you sick!
Registered Linux User # 279330
ahh, virus... or should i say, virii, for many :-)
i used to collect them when i was in high school for study purposes. i get the hang of it in making one using those lame auto-generated-virus softwares and distribute it among my friends hehe
anyways, virus by my own definition, is a program that runs on your computer and deletes/modifies specific files. the worst virus i've encountered was the Chernobyl virus. it obliterated the whole Win98 system... lost all my files im working on.
Isn't virii plural for virus.
To err is human, to moo bovine.
i suppose it is... i havent look over it on the dictionary. i just took the word as what those virus authors say it so. if it isnt, then, i stand corrected hehe
hey, i havent read a report about a virus attacking linux boxes, with the excemption, of course, of trojans and rootkits.


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Majestic Athletic Boston Red Sox David Ortiz 2013 World Series Champion Authentic Cool Base Home Jersey
Item # 29827246
|Members of The League get 5% back when you spend $100! (see promotion details)
Product Details
Give your favorite MLB® slugger his due props in this Majestic® men's Boston Red Sox® 2013 World Series® Champion home jersey! It's designed with moisture-wicking material to ensure you stay cool even in extra innings, and the eye-catching graphics let you show off your pride at the ballpark.
- 100% polyester mesh
- Authentic jersey
- Designed with moisture-wicking Cool Base® technology
- MLB® team name arched across front; player's number on back
- 2013 World Series® Champion logo on right sleeve
- Jock tag above left hem
- Officially licensed
- Made in the USA


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- »
- Ich liebe Budapest »
- Shopping
For both contemporary and traditional fine porcelain, one should definitely go visit Herend.
The most popular motifs made by the company are the Victoria pattern of butterflies and wildflowers which were designed for the British Queen during the mid-19th century.
There is also a more central situated Belváros branch located at József nádor tér 11;
Phone: (36-1) 3172-622; Public Transport: Metro 1 Vörösmarty tér.
Budapest Wine Society (Bortarsasag)
Bortársaság used to be known as the Budapest Wine Society. It has 6 retail outlets and has an exceptional selection of Hungarian wines. The people working there are true experts on the subject of Hungarian Wines.
Their offer ranges from wines (Hungarian, imported, sparkling), Pálinka (fruit brandy) and spirits to glassware, accessories and delicacies. For those who want to know more before arriving at Bortársaság, their website already provides a top 12 of their wines with detailed information on the history of the wine, the flavours and aromas.
The Great Market (Nagycsarnok)
The Great Market or the Central Market Hall is Budapest's biggest market place for food and has been attracting visitors ever since it was renovated for the millennium in 1996. These days it has dozens of small and big stalls on the first floor where Hungarian folk costumes, dolls, painted eggs, embroidered tablecloths, carved hunting knives and so on are being sold.
On the main floor you can retrieve all different kind of treats at a much cheaper price compared to the shops in Váci Utca. There is a great amount of butchers.
City Park Flea Market
This is a huge outdoor flea market – a kind of Hungarian boot or garage sale – held next to petőfi Csarnok in the City Park.
The usual stuff on offer – from old records and draperies to candles, honey and herbs. Sunday is the better day. It is also a good place if you are interested in former used memorabilia from the communist era. Some of the items sold are actually vintage products where as others could be considered utterly worthless.


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Bail Hearing Continues As Oscar Pistorius Contests Murder Charge
Relatives of South African Olympic sprinter Oscar Pistorius, his... News PhotoAimée Pistorius,Appearance,Brother,Carl Pistorius,Family,Father,Females,Henke Pistorius,Horizontal,Killing,Law,Males,Oscar Pistorius,Pretoria,Shooting of Reeva Steenkamp,Sister,South Africa,ViolencePhotographer ALEXANDER JOECollection: AFP 2013 AFPRelatives of South African Olympic sprinter Oscar Pistorius, (From L) his sister Aimee, his brother Carl, and his father Henke appear on February 22, 2013 at the Magistrate Court in Pretoria. Pistorius battled to secure bail as he appeared on charges of murdering his model girlfriend Reeva Steenkamp on February 14, Valentine's Day. South African prosecutors will argue that Pistorius is guilty of premeditated murder in Steenkamp's death, a charge which could carry a life sentence. Pistorius denies the charge, saying that he shot 29-year-old Steenkamp repeatedly through a locked bathroom door in the dead of night by accident, having mistaken her for a burglar. AFP PHOTO / ALEXANDER JOE (Photo credit should read ALEXANDER JOE/AFP/Getty Images)


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In Fiscal Year 2013, SSA assigned approximately 5.8 million original Social Security numbers (SSNs) and issued about 10.3 million replacement SSN cards. In the same fiscal year, SSA also recorded approximately $689 billion in employment taxes related to earnings under assigned SSNs.
Assigning SSNs only to those individuals authorized to obtain them, protecting information once the numbers are assigned, and accurately posting earnings reported under SSNs are critical SSA missions.
These investigations and reports describe our efforts to meet these missions.