text:
Safety Study of Recombinant Listeria Monocytogenes(Lm)Based Vaccine Virus Vaccine to Treat Oropharyngeal Cancer (REALISTIC:)
Recruitment status was Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
It is the investigators intention to investigate whether a specially designed vaccine, based on a genetically modified strain of the bacterium Listeria monocytogenes and called ADXS11-001 is safe to use and is able to boost the immune system of patients presenting with Human Papilloma Virus (HPV) associated oropharyngeal cancer (OPSCC). It is hoped that the vaccine will boost the immune system so that immune cells with cell killing properties are able to attack any cancer cells remaining after the patients have been treated. However, the vaccine is so novel the investigators are not sure whether it is able to do this and before they can answer that question in a larger group of patients they need to make sure that the vaccine is safe to use and has some effect on the immune system in the patients for whom they intend its ultimate use. In a previous study, patients with incurable cervix cancer which is caused by the same virus, were vaccinated with ADXS11-001. Although all patients vaccinated experienced flu-like symptoms, patients tolerated the vaccine well with no patient suffering long term adverse effects of vaccination. However, because the patients and cancer type was so different in this earlier study, the investigators need to test whether ADXS11-001 is also safe in patients with HPV associated OPSCC. That said, the earlier study guided the dosing schedule for the current study and patients entering the REALISTIC trial will receive lower doses than those administered to patients in the earlier cervix cancer study. It is hoped that by doing this, patients will experience fewer side effects of vaccination without reducing the chances of stimulating the immune system.
HPV-16 +ve Oropharyngeal Carcinoma
Biological: ADXS11-001
Phase 1
|Study Type:
|Study Design:
|Endpoint Classification: Safety Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|REALISTIC: A Phase I, Dose Escalation Trial Of Recombinant Listeria Monocytogenes (Lm)-Based Vaccine Encoding Human Papilloma Virus Genotype 16 Target Antigens (ADXS11-001) In Patients With HPV-16 +ve Oropharyngeal Carcinoma
- Safety [ Time Frame: 12 months ] [ Designated as safety issue: Yes ]Occurrence of drug-related grade 3 or 4 systemic or local adverse events (defined using the NCI Common Criteria Adverse Events (CTCAE) Version 4.03
- Translational [ Time Frame: 24 Months ] [ Designated as safety issue: No ]Demonstration by ELISPOT assay of the frequency of IFN-γ secreting lymphocytes recognising MHC class I and II-restricted epitopes within HPV-16 E& protein in peripheral blood at sequential time-points before, during and up to ten months after vaccination course. This protocol has been used by our group to demonstrate vaccine induced T cell responses in a previous HPV vaccine trial.
|Estimated Enrollment:
|Study Start Date:
|February 2012
|Estimated Study Completion Date:
|October 2014
|Estimated Primary Completion Date:
|February 2014 (Final data collection date for primary outcome measure)
Biological: ADXS11-001
|Ages Eligible for Study:
|18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Histologically confirmed HPV-16 +ve, p16 +ve OPSCC.
- Patients in remission from disease, i.e. complete response (CR) or unconfirmed complete response (CRu) in the case of non-surgical treatment or complete macroscopic resection of tumour and associated cervical lymph nodes in patients undergoing surgery.
- Completion of standard therapy for malignancy at least 6 weeks before trial entry.
- A positive result following anergy testing.
- Written informed consent and the ability of the patient to co-operate with treatment and follow up must be ensured and documented.
- Age greater than 18 years.
- World Health Organisation (WHO) performance status of 0 or 1.
- Life expectancy of at least 12 months.
- Haematological and biochemical indices (these measurements must be performed within 8 days prior to the patient going on study):
- Haematological:
Haemoglobin (Hb) > 10.0 g/dl Neutrophils ≥ 1.5 x 10e9/L Platelets (Plts) ≥ 100 x 10e9/L
- Baseline liver function tests:
Serum bilirubin ≤ 1.5 x upper normal limit Serum alkaline phosphatase, alanine amino-transferase (ALT) and/or aspartate amino-transferase (AST) < 1.5 x ULN.
- Baseline renal function test:
Calculated creatinine clearance > 50ml/min (uncorrected value) or isotope clearance measurement > 50ml/min.
- Female patients of child-bearing potential are eligible, provided they have a negative serum pregnancy test prior to enrolment and agree to use appropriate medically approved contraception during the study up to six months after the last vaccination Male patients must agree to use appropriate medically approved contraception during the study up to six months after the last vaccination.
Exclusion Criteria:
- Receiving, or having received, chemotherapy or radiotherapy within 6 weeks of trial entry.
- Having undergone surgery +/- PORT within 6 weeks of trial therapy
- A negative result following anergy testing.
- Known chronic active infection with Hepatitis B, Hepatitis C or Human Immunodeficiency Virus (HIV).
- Current active autoimmune disease.
- Current active skin diseases requiring therapy (psoriasis, eczema etc).
- Ongoing active infection.
- History of anaphylaxis or severe allergy to vaccination.
- Previous myeloablative therapy followed by an autologous or allogeneic haematopoietic stem cell transplant.
- Patients who have had a splenectomy or splenic irradiation, or with known splenic dysfunction.
- Receiving current immunosuppressive medication, including corticosteroids within 4 weeks of the first dose.
- Pregnant and lactating women.
- Ongoing toxic manifestations of previous treatment.
- Major thoracic and/or abdominal surgery in the preceding four weeks from which the patient has not yet recovered.
- Patients with any other condition which in the Investigator"s opinion would not make the patient a good candidate for the clinical trial.
- Concurrent congestive heart failure or prior history of class III/ IV cardiac disease
Please refer to this study by its ClinicalTrials.gov identifier: NCT01598792
|Contact: Gemma E Simpson, BSc
|+44 (0)151 794 8054
|United Kingdom
|Velindre NHS Trust
|Not yet recruiting
|Cardiff, United Kingdom, CF14 2TL
|Contact: Mererid Evans
|Principal Investigator: Mererid Evans
|Aintree University NHS Foundation Trust
|Liverpool, United Kingdom, L9 7AL
|Contact: Terence Jones
|Principal Investigator: Terence Jones
|The Royal Liverpool and Broadgreen University Hospitals NHS Foundation Trust
|Not yet recruiting
|Liverpool, United Kingdom, L7 8XP
|Contact: Terence Jones
|Principal Investigator: Terence Jones
|The Royal Marsden NHS Foundation Trust
|Not yet recruiting
|London, United Kingdom, SW3 6JJ
|Contact: Kevin Harrington
|Principal Investigator: Kevin Harrington
|Principal Investigator:
|Terence Jones, BSc,FRCS,MD
|University of Liverpool
Additional Information:
No publications provided
|Responsible Party:
|Prof. Terry Jones, Professor of Head and Neck Surgery, University of Liverpool
|ClinicalTrials.gov Identifier:
|NCT01598792 History of Changes
|Other Study ID Numbers:
|Study First Received:
|May 11, 2012
|Last Updated:
|May 16, 2012
|Health Authority:
|United Kingdom: Medicines and Healthcare Products Regulatory Agency
Additional relevant MeSH terms:
Oropharyngeal Neoplasms
Head and Neck Neoplasms
Neoplasms by Site
Otorhinolaryngologic Diseases
Otorhinolaryngologic Neoplasms
Pharyngeal Diseases
Pharyngeal Neoplasms
Stomatognathic Diseases
ClinicalTrials.gov processed this record on October 09, 2015


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subset: commoncrawl


text:
Blueshirt fans I would highly recommend
checking out Tortorella's break-up day remarks which you can find on a few of
our links to the Pro Blogs.
I know many fans had mixed
emotions about Torts; his constant line changes, the way he carried himself and
the general inconsistency throughout the year. However, I think he deserves
another year for two key reasons.
- He is committed to
getting younger and not afraid of pushing veterans out of the way to do so. This
is a league where your "home grown" talent wins you games, just look at the NHL's
top teams such as Chicago, Pittsburgh,
and Washington.
In reference to Parenteau, who Torts said
was one of the top skill guys on this team
and with some hard work in a few key areas could be a huge part of next years team. I couldn't agree more as P.A. has a
nose for the net and I would love to
see him get a real shot a becoming a top guy on this team. The reason I mentioned him specifically; being the skeptical
Ranger fan I am, is he would have been a typical
guy the Ranger organization would have tried for a few games and dumped in the first juicy deal that came along.
He also realized the importance of
Anisimov and his own critical role as a coach in
finding the "right" spot for the talented youngster on this team.
- The next positive about Tortorella is his
willingness to point out a clear problem with
the locker room. Generally a coach should not get too involved in this aspect of the team, as it is key for the players
to come together and develop their own identity;
but keeping a pulse of what goes on is vital.
We knew things were not great but after
some of the comments yesterday, it seemed
like this room was a disaster for most of the year. It also seems the problems did not stem from the team
leadership (The C and the A's), but rather a few
cancerous players within.
No specific names were mentioned but I bet
if Torts has his way he will find these guys
and send them packing in one way or another.
I know this is a controversial
post but I truly believe he has the strength to fight the tendencies of this
organization and go with a youth movement. We know the core of this team is a
young hard working bunch of guys, but if he stays true to his word by
cultivating the youth and seeking out the problems…I am in.


text:
Stormfront Pack
In Stock Product Number: 24329
Whatever the fishing gods throw at you, from tropical thunderstorms to heavy-water river swims, you can fish through it all knowing your dry goods are safe – as long as they're inside the Stormfront Pack. This ultra-simple waterproof fishing pack is now made with waterproof PU exterior coating and interior single-side TPU-coated nylon, 100% waterproof welded construction and an easy-to-use, fully waterproof TIZIP main zipper. It's comfortably supported by a removable shoulder-strap harness that features a 3-D spacer mesh panel for air circulation and a new, more comfortable waistbelt. Take the harness off and you have the perfect fishing bag for wet boat decks. There's also a new external, water-resistant stash pocket, while inside, the glued-in zippered mesh pocket keeps valuables organized. The harness system includes tool attachment and storage capabilities, plus as an added bonus, it's compatible with the Minimalist Vest and the vest portion of our Pack Vest (available in previous seasons) as well as the our new Convertible Vest.
* This product does not qualify for shipping to all countries.
- 100% waterproof, fully welded construction with a single-side TPU coating
- 100% waterproof TIZIP zipper with waterproof materials and construction; exterior water-resistant zippered stash pocket; internal zippered mesh pocket
- Harness and waistbelt system provides support and comfort
- 3D spacer mesh back panel wicks moisture, dries quickly and allows air circulation
- Exterior quick access water-resistant stash pocket
- Exterior rod tube holders
- Compatible with Convertible Vest (sold separately)
Gender: Unisex
Weight: 805 g (28.4 oz)
Material: Pack: 11.75-oz 800-denier 100% nylon, with a single-side TPU coating and DWR (durable water repellent) finish. Harness back, panel and waistbelt: 4.55-oz 100% nylon 3-D spacer mesh
Volume: 28 L (1709 cu in)
Season: F14 S15 F15
Vendor ProductId: 49153
Review ProductId: 24329


text:
Obtain or Upgrade Water Service
Relocation of Development & Water Services
Seattle Municipal Tower
700 5th Ave., Seattle, WA 98104
Development Services Office
(206) 684-3333 /email
For water services
27th floor
M, W, Th, F: 8:00 a.m. – 5:00 p.m.
Tue: 10:30 a.m. – 5:00 p.m.
4th floor (lobby entrance)
Information & Payments desk
Sign up for updates about construction services.
New paving restoration rules begin - October 1, 2015
We will no longer provide paving restoration for new water service installations and retirements. Applicants will now need a Seattle Department of Transportation Street Use Permit (51M) for pavement restoration or a Street Improvement Plan (SIP) showing restoration of water service related work, or applicable paving permits if you are working in other jurisdictions (new service and retirements of old services). For more information, please see SDOT Street Use Franchise and Utility Permits or contact SPU's Development Services Office.
Complete the following customer checklist if you are a property owner who wants a new connection to Seattle's water supply system or to upgrade your existing water service.
Customer checklist
View printable checklist (pdf)
View scope of work form (pdf)
Determine if there is adequate water for your project.
- Apply for and receive an approved Water Availability Certificate (pdf)
- Submit plan and receive plan approval (choose one):
- Large Services/Hydrants (greater than two inches)
- Submit plan to Seattle Public Utilities (SPU) for water service
- Acquire SPU Engineering approval (your account executive will help with this)
- Acquire site-specific job costs from SPU
- Small Services (two inches or less)
- Provide site sketch showing desired location for new services
- Large Services/Hydrants (greater than two inches)
- Street restoration: Customers are responsible for the full cost of street right-of-way restoration, which may include paving, sidewalks, wheelchair ramps, and other improvements. Applicable site-specific requirements are determined through the Seattle Department of Transportation's (SDOT) Street and Sidewalk Opening and Restoration Director's Rule, 5-2009. Customers have two options to fulfill this responsibility (choose one):
- Seattle Public Utilities (SPU) restores
- Submit a signed Water Service Application and Water Agreement (pdf). If you designate SPU as the street restorer, SPU will provide you with your final fee. Additional fees may apply if the customer changes the scope of work, design, or location of the new services after plans are approved.
- Pay fees associated with water service installation and street restoration
- Owner restores (Hire an SDOT approved private contractor)
- Provide SPU with SDOT Street Restoration Permit or copy of Street Improvement Plan and SIP permit number
- Submit signed Water Service Application and Water Agreement (pdf)
- Pay fees associated with water service installation
- Seattle Public Utilities (SPU) restores
Questions? Contact a utility account executive. Email email@example.com or call (206) 684-3333.
Related Links
CAM 2600 (pdf) Street Use Utility Permitting Requirements
CAM 2601 (pdf) Pavement Restoration for Utility Service Connections
CAM 2602 (pdf) Becoming a Registered Pavement Restoration Contractor
Water Service Standard Charges
Water Service Client Assistance Memo
Backflow Prevention Requirements
Backflow Test Report Form (pdf)
Water Service Application and Agreement (pdf)
Water-Saving Tips and Rebates for Commercial Buildings
Water Service Project Scope Of Work (pdf)


text:
Hello and thanks for your time.
I have a cgi (formail) driven form and I would really like this form to be php driven, is there a way I can utilize my existing form structure and layout or will I have to build a new one, any help or suggestions on how to do this would be greatly appreciated.
Thanks heaps


text:
PROVIDENCE — It's very good to be Marshon Brooks these days.
To the Providence College senior, the basket must seem as large and as inviting as Narragansett Bay on a summer's day. The prodigious scoring outputs are quickly becoming a regular feature, as Saturday saw Brooks once again torch the strings with great frequency.
PROVIDENCE — It's very good to be Marshon Brooks these days.
To the Providence College senior, the basket must seem as large and as inviting as Narragansett Bay on a summer's day. The prodigious scoring outputs are quickly becoming a regular feature, as Saturday saw Brooks once again torch the strings with great frequency.
PC made a hard push to the finish line in an 82-70 triumph over Alabama at The Dunk because Brooks took control of the offense down the stretch. That is, he shouldered the load. Finishing with a career-tying 33 points is one thing, but scoring 14 points in the final 12 minutes with the outcome still up for grabs is the stamp the swingman placed on his latest scoring spree.
At that point the Friars were nursing a 59-57 lead over their SEC opponent. The Crimson Tide went up 61-59 at 9:22, but that's when Brooks ratcheted things up. A mixture of jump shots and aggressive drives to the rim helped put PC up 71-64 after Brooks swished home a 3-pointer at the six-minute mark. That capped off an avalanche of a sequence in which the Georgia native was responsible for nine of his team's 12 points.
"He put his team on his back today," was Alabama's JaMychal Green's way of tipping his cap to Brooks. "He's a tough player to guard. Kudos. He just had a great game."
Brooks finished the day shooting 9-of-18 from the floor to go along with eight rebounds. What had head coach Keno Davis raving afterwards was that his top playmaker got to the foul line 16 times, making 13. Conversely Alabama went to the charity stripe 15 times for the entire game.
"Marshon is getting better before everyone's eyes. I think it's taken him time to realize that he doesn't have to make the spectacular play every time. He's so talented that the higher percentage play is good enough," said Davis. "On a night in which Vincent Council struggled, we had to rely on him for a lot of the scoring. That's a credit to him to understand that and to make better and better moves."
You only have to go back to Monday against Brown to find Brooks' previous 33-point outburst. He entered Saturday as the Big East's second leading scorer, his 22-point average trailing UConn's Kemba Walker (28 ppg). Asked how much confidence he's playing with, Brooks quickly answered, "As much as I ever have."
While Brooks saved his best for last, the Friars were also buoyed by a strong performance from Gerard Coleman. The freshman notched 18 points on 8-of-12 shooting with six rebounds. With Council suffering through a rare off game – 2-of-10 for eight points and seven assists – the contributions provided by Coleman were most welcome by Davis and the Friars.
A 21 percent shooter from the 3-point stripe coming in, Coleman burned the Tide for a key trey with seven minutes remaining, a shot that gave the Friars some breathing room at 68-61. The Boston product added a few mid-range jumpers in keeping with Davis' mantra of players making improvements as the season progresses.
"He's got just so much talent out there and has a chance to be a very special player," raved Davis. "Not many first-year players get a chance to start in the Big East. Only the truly special ones do, and he's one of those guys."
The game started out back-and-forth as the teams went into halftime tied at 40 apiece. High-flying forward Tony Mitchell paced Alabama with 15 points in the first half, though he managed just five in the second half on his way to collecting 20 points. Green, playing in his first game back after a three-game suspension, added 15 points and 11 rebounds off the bench.
Alabama jumped out to leads of 49-44 and 53-48 early in the second half before the Friars clawed back. A spinning drive in the lane by Council and a 3-point play from Brooks erased the deficit before Alabama made what turns out it's last stand of the game with still nine minutes to go. PC then hit Alabama (4-5) with a dizzying 19-3 run that allowed the Friars to go up 78-64 late and seal up the team's 10th win in 12 games.
"I liked the fight we showed after the Boston College loss," said Brooks.
"My mind was thinking back to the BC game (when PC was up 62-61 on 'Bama with 7:44 left)," said Coleman. "We didn't want to wait until the last minute to make a comeback."
RIM RATTLERS: Saturday's attendance was announced at 8,056, which was PC's second-highest total after the URI game. … The Crimson Tide became just the second team this season to out-rebound the Friars, 38-37. … Providence is now off until Dec. 21 for exams, which start up on Monday. "I am," said Coleman when asked if he's ready for a break from basketball after opening the season with 12 games in 29 days. "Study, rest and practice and get ready for Sacred Heart (on the 21st)."


text:
Where to Stay
Jomtien Beach, Pattaya
+66 850899965
View Talay 2-bedroom villa is situated just 500 meters from Jomtien beach in what is one of the best holiday locations imaginable. Enjoying untold privacy within an estate with 24-hour security, the villas has two bedrooms, a private swimming pool and lots of seclusion to enjoy your Pattaya holiday experience. With a top location, homely atmosphere and attractive rates – what are you waiting for?
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Check out : 11:00
High Season : December - February
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The closest destination to this result :
See & Do in Pattaya :


text:
Entering Tuesday, all but four members of the Mets' healthy members of the Mets' 40-man roster will be in the big leagues. Every healthy pitcher and catcher is in the big leagues already. The four exceptions: 3B/2B/1B Wilmer Flores, 2B Reese Havens, CF Cesar Puello and OF Juan Lagares. Neither CF Matt den Dekker nor RHP Zack Wheeler are on the Mets' 40-man roster.
Flores, hit .300/.349/.479 overall between advanced-A and AA with 30 doubles and 18 homers and 38 walks against 60 strikeouts in 130 games. In the month he turned 21, he bashed .377/.436/.632 in AA with 5 homers, 10 walks and 15 strikeouts in 28 games in August. The man can hit. However, he is still looking for a position. On the 2012 Mets, he would not have played third base over David Wright, second over Daniel Murphy or first over Ike Davis. He should make his Major League debut sometime in the 2013 season after beginning the year in AAA. The position he'll play when he makes his MLB is still unclear, but he'll hit.
Puello, playing the whole year as as 21-year old, hit .260/.328/.423 in 66 games in advanced-A. I still really like the tools, but that's not close to MLB ready.
After a slow start, Lagares recovered to hit .283/.334/.389 in 130 games in AA with nice defense at all three outfield spots. The 23-year old Lagares, who bats from the right side, beat lefties at a .331/.379/.474 clip in 133 AB, while hitting for little power against righties (.265/.318/.358 – 366 AB). He would be a nice right-handed piece of a platoon for any of the Mets' left-handed swinging outfielders.
Reese Havens at age 25 in AA: .215/.340/.351 with 113 strikeouts in 94 games. That 40-man roster spot is shaky.
There was no reason to call up den Dekker. As a member of the 2010 draft class, the 25-year old is not rule eligible yet and after raking in AA (.340/.397/.563) struggled badly in AAA (.220/.256/.373 with 90 strikeouts in 77 games).
As for the 22-year old Wheeler, the Mets shut him down after 149 combined innings between AA and AAA. That's a 34-inning jump over a year ago when he worked exclusively at the advanced-A level for the Mets and Giants. He told Adam Rubin of ESPNNY, that he could feel the extra strain on his arm.
Wheeler's stuff is electric, but he still must improve his control. He walked 12% of the opposing batters he faced at AAA. Unlike many high school draftees, Wheeler was 19 when he signed in 2009, so he will be rule 5 eligible for the first time this year forcing the Mets to add him to the 40-man roster this off-season. As long as he's healthy, he will make his MLB debut in 2013.


text:
PFB Vanish Numb-IT
We know you want the goods as soon as possible, which is why orders received by 3pm ET leave our warehouse the very same day. We'll send you an email that day to confirm shipment and the email will include your tracking information.
Our warehouse is closed Saturday & Sunday, so orders received after 3pm ET on Fridays will not ship out until Monday.
Based on 2 Reviews
HollySome ReliefSo, I have a very low tolerance to pain and I just purchased an epilator and wanted something to help dull the pain. I used the epilator on my legs prior to receiving this and will say that this stuff did help when I placed it on the lower half of my legs. It DID NOT help with the pain of having the hair pulled out but it made the painful feeling go away much faster. With that being said, the numbing cream didn't help me on the upper half of my legs where it is more sensitive. If you are just purchasing this for your face, then it's worth purchasing, simply because it eases discomfort. However, I was disappointed with the results. I was expecting more of a numb feeling, which I only felt when I used it on my face. I wouldn't purchase this again.
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Seaspray 3.Works GreatThis product is the best. I wouldn't be able to sit in a waxing session for armpits or bikini line without it. GREATEST EVER!!!1 out of 1 shoppers thought this review was helpful.
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Ashes 2013-14: How Darren Lehmann transformed Australia
For a man who freely admits his partiality for a cold beer, Darren Lehmann's part in the Ashes victory celebrations in Australia's changing-room - being drenched with spraying lager by his celebrating players - was entirely appropriate. Perhaps the only problem was the danger of it putting his fag out.
Lehmann's influence on this Australian team since he was appointed coach after Mickey Arthur's sacking in June was being lauded here even before the urn was finally won back at the Waca on Tuesday afternoon.
Now, after a team that had lost seven of their previous nine Tests has hammered England in their last three and may yet go on to record a 5-0 Pom-wash, he is almost more the nation's darling than captain Michael Clarke or fast bowling wrecking-ball Mitchell Johnson.
Quite how much of this sudden success is down to Lehmann takes a little longer to divine. But one thing is immediately obvious to anyone who has been around the team over the past year: it has never been as much fun as it is now.
Each day's training begins with a joke, told by a member of the playing or support staff after being given 24 hours notice. When the team wins, there are beers on the bus. When they don't, the team does not fracture as it has in the past.
"He's an old-school kind of bloke who tells it how it is," says Glenn McGrath, Lehmann's some-time team-mate in the national side and covering this series for Test Match Special. "He's very positive and relaxed, and he's exactly what the team needed.
"He's a totally different character to Mickey Arthur. I've always got on well with him, but sometimes the way the South Africans have gone about their cricket is different to Australians.
Lehmann's career highlights
1999: Hits winning runs for Australia in World Cup final
2001: Helps Yorkshire to their first County Championship since 1968 with 1,416 runs
2003: Takes catch for Australia to retain the World Cup
2008: Ends playing career after spell with Rajasthan Royals in the IPL
2009: Coaches Deccan Chargers to IPL title
2012: Coaches Queensland to Sheffield Shield in first season in charge
2013: Appointed coach of Australia
2013: Guides Australia to Ashes victory against England
"When he came in there were a lot of issues in the team, and something had to happen. 'Boof' brought a calming influence."
The issues that McGrath is referring to were between both coach and some players - witness the suspension of four of them on the disastrous tour to India earlier this year - and within the team, not least between Clarke and then vice-captain Shane Watson.
Arthur, who still lives in Perth, was commentating at the Waca as Australia sealed the Ashes with their 150-run win. An engaging man, he points out with little rancour that Lehmann has perhaps been blessed with a little more luck than he ever was.
"We wanted to play the brand of aggressive cricket that Australia are playing today," he told BBC Sport. "That was certainly the mantra.
"What we didn't have during that period was Ryan Harris, who was out for a long time with injury, and we didn't have Mitchell Johnson, so it was a little bit tougher. We didn't have Brad Haddin, who had such a tough time with his daughter.
"Mitchell gets rid of the top order but also the tail very quickly. Ryan asks questions of the batsman every over. To have him fit and firing now is very special for the leaders in that group.
"We tried a lot of young players. David Warner is two years more mature. So is George Bailey.
"There's no doubt that a team gets a lift with a new voice. I came in after Tim Nielsen and we won that first series against India playing exactly the sort of aggressive cricket we've seen here. And now England look mentally shot, because of the aggressive cricket that Australia have played."
For all his public image as a lovable larrikin who puts pies before Pilates and fags before fartlek, Lehmann lacks nothing as a competitor. Like Arthur, he wants his teams to be hard. More successfully than Arthur, he has got them to perform at the same time.
"I think the atmosphere and the belief and getting guys playing a good attacking brand of cricket was essential for us with where we wanted to get to," he said in the aftermath of the win in Perth. "I think we've shown that in the first three Test matches."
McGrath, as friendly off the pitch as he was once unremittingly hostile on it, agrees.
"Australian teams play best when they have a bit of mongrel about them," he says. "Just that bit of aggression, being in your face, playing with heart. And when you've got a guy like Johnson playing the way he has, that fires up the whole team. You grow an extra limb, as they say."
Neither is Lehmann a soft touch with his own players. While he may have been mates with Clarke when the kid known as Pup made his Test debut nine years ago, he has set exacting standards; on Monday evening, with his side on the brink of the Ashes, he gave them "a bit of a lashing" for the way they had bowled against Ben Stokes in the final session.
"We're brutally honest," Lehmann says. "But they keep learning and that's all we want to do. The way they've all gone about it on and off the field has been exceptional."
Then there are the plans designed for each of England's dangermen, so successful that the key men in the tourists' triumph three years ago - Alastair Cook and Kevin Pietersen, James Anderson and Graeme Swann - have all been entirely neutered.
Damien Fleming on Lehmann
Writing in Australian newspaper The Age at the time of Lehmann's retirement in 2007, his former Australia team-mate Damien Fleming described him as "the room-mate from hell".
He said: "He smoked, drank and snored like a rioting elephant. We roomed together in Sri Lanka for a one-day tournament that was under heavy security after we had pulled out of going there for the World Cup earlier in the year.
"We were told we couldn't leave the hotel, which sent us stir crazy for the three weeks we were there. We passed the time by me questioning him about one of his favourite things - the McDonald's menu.
"I would ask questions such as: How much is a Big Mac meal deal, six nuggets and a caramel sundae? He would have 15 seconds to answer. We had hours of fun."
"The way we wanted to bowl to each particular batsman from one to 11 and the way the bowlers went about it, was exceptional," says Lehmann. "I don't think they've made over 400 in the last eight Test matches, so our plans are pretty good.
"The simple fact is we didn't bat well enough in England, full stop. We've batted well here and made some runs.
"In England we lost those key moments. Here we've won them. We kept going at them day in and day out."
Key blows were landed even as that corresponding series in England last summer was lost 3-0. Cook and Pietersen both averaged in the low 30s. Anderson, after a man-of-the-match display in the first Test at Trent Bridge, struggled to exert the same influence again.
What appears to be a miraculous renaissance in the last 28 days was already underway in the UK. Had it not been for rain at Old Trafford and the Oval, the events of the past three Tests might have come as less of a statistical shock.
"Everything was heading in the right direction at the end in England," says McGrath.
"They found a better combination in the batting order by the Oval, while England were coming off a bit, probably thinking everything was fine.
"But I'm not sure they played well enough to win 3-0. I think Australia lost the Ashes. England had a lot of issues covered up by Ian Bell playing so well, and here he hasn't."
Along with John Inverarity, the chairman of Australia's selectors, Lehmann has shown admirable calm and consistency, even if injuries have gone his way. After Australia used 17 players in those preceding Ashes and a full 22 players in their run of nine winless Tests, they have stuck with the same side throughout this series.
The big challenge for Lehmann is now making it last.
This is already an ageing team. Chris Rogers is 36, the same age as Haddin. Harris is 34, Clarke and Watson 32. Bailey, three matches into his Test career, is already 31.
There are good young players to come in - Alex Doolan with the bat, James Pattinson and Pat Cummins with the ball, Peter Nevill with the gloves - but they are either unproven at the highest level or so far susceptible to injury.
"My worry for the Australian side going forward is that it needs to be sustainable, but that the holes we tried to fill during my tenure are still there," says Arthur.
"It's an old team. Who is the next opening batsman? Is Bailey good enough? Who is the next keeper? What happens when Harris goes? They will face all those issues in the next year or two."
Tougher challenges also lie in wait. Australia must next travel to South Africa, the number one ranked team in Test cricket. Arthur too started brilliantly, winning that first series against India 4-0, only for his authority and results to fade away.
Lehmann must be aware of those precedents. But for now he can bask in both the success of his team and the gratitude of his nation.
Comment number 115. Posted by Woofaon 18 Dec 2013 21:45
I agree 112
Comment number 114. Posted by snoochon 18 Dec 2013 21:43
108-Don't pay any attention to Sydney!Anyone who thinks a yob like Lehman has restored 'national pride' is the ignorant of the coach who launched a vicious personal attack on an opposition player, instead of losing with grace. Who brought an even bigger yob like Warner back into the fold, after what he did. Who encouraged his captain to drag the game into the gutter when the world was watching.
Comment number 113. Posted by MattyTheWhoLoveron 18 Dec 2013 21:43
This comment was removed because it broke the house rules. Explain
Comment number 112. Posted by Zee Zee Topon 18 Dec 2013 21:38
This comment was removed because it broke the house rules. Explain
Comment number 111. Posted by A Blighon 18 Dec 2013 21:34
England are in decline, Australia in the ascendency.
England's policy of developing foreign talent is continuing unabated.
Stokes-kiwi, Ballance-Zimbawean, Robson-Australian.
Comment number 110. Posted by MattyTheWhoLoveron 18 Dec 2013 21:32
This comment was removed because it broke the house rules. Explain
Comment number 109. Posted by Howie3on 18 Dec 2013 21:30
Lehmann will have made a difference, but the outcome of a match rests primarily with the players. Cricket revolves round the belief (or otherwise) that you can dominate the opposition, and England suffered a collective loss of form and confidence. A brief glance at the history books suggests that we shouldn't be surprised if England lose an Ashes series Down Under...
Comment number 108. Posted by Numbnutson 18 Dec 2013 21:28
@102sydney - "most of the english team are foreign" Can you explain that one for us!! Are you saying we lost because we have a "foreign" coach and most of the team are foreign!!!
Comment number 107. Posted by Bruce Walkeron 18 Dec 2013 21:27
#105 - excellent point and this will be the real test for Lehmann. The typical ignorant comments on here exaggerating the weaknesses of both teams should be put aside. Australia will be strong on bowling - their challenge will be in the batting as recent new recruits have not set the heather alight.
Comment number 106. Posted by WhatwouldIknowon 18 Dec 2013 21:26
Also on the sledging element, is it a case of "Some big boys said something nasty to me" ? Heaven forbid some of you should go near English schools where parents either turn a blind or or actively encourage their little darlings to indulge in this or worse... Society has to own up here, oh I forgot 'there is no such thing as society, only the individual'... Check your history for that one...
Comment number 105. Posted by CFMcAleeron 18 Dec 2013 21:19
The interesting point is which side does best in its succession planning. Australia's efforts to replace (the possibly immediately
irreplaceable) Langer, Hayden, Michael Hussey, Warne, McGrath, etc., were laughable. Let's see how we get on with replacing Pietersen, Swann, Prior, Anderson, to,say nothing of those who,will be at or past 30 by 2015,e.g., Cook, Bell & Bresnan.
Comment number 104. Posted by naigibon 18 Dec 2013 21:17
What has helped Lehmann enormously is that England have been useless.
Comment number 103. Posted by WhatwouldIknowon 18 Dec 2013 21:10
There are references to average or in some cases worst Australian team ever, I suggest you look at the team cobbled together after Packer's raid... However, let us remember on the sledging element that both sides have been involved, it only works if you get a response back! Rogers is there to a job, he does it, he did it for an array of Counties, Bailey likewise as an additional leader, 28 counts
Comment number 102. Posted by SydneyStatsManon 18 Dec 2013 21:09
like i said yesterday, there is no shame in losing a cricket match.
how you lose is a different matter though. england rolled over too easily and aus did similar in india under the uninspiring mickey arthur.
now we have aussie coach we have our national pride back and you feel like you are representing your country. flower is zimbabwean and most of the english team are foreign.
Comment number 101. Posted by Bruce Walkeron 18 Dec 2013 21:07
#98- for once it was not the money dictating the short gap between series. Due to the World Cup being in Aus and NZ in Feb and March 2015 it was decided that England should not have to effectively tour down under for 6 months (normal schedule would have had the return series starting in Nov 2014)
Comment number 100. Posted by Woofaon 18 Dec 2013 21:02
Mattythewholover......it seems you need a cuddle mate......for the next 2 years
Comment number 99. Posted by MattyTheWhoLoveron 18 Dec 2013 20:56
This comment was removed because it broke the house rules. Explain
Comment number 98. Posted by Sams Townon 18 Dec 2013 20:48
@77. snooch
After spanking the Aussies just a few months ago - there was no appetite for this series so soon after.
You have a point...........when a team wins the Ashes after 5 tests they shouldn't be flying out to defend them just 3 months later.............crazy idea........money money money
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text: Archive A New Spring Dish From Start To Finish April 26, 2013 | Posted by chefmorimoto in Art, Food & Wine, News| 1 comment I've been working on new dishes for the spring menu at Tribeca Canvas. As many of you know from my sushi art, I like to visualize and draw a new idea on paper before actually cooking and plating the dish. Here's how I imagined my new red snapper dish from start to finish. This is […] Read more


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Thread: Anyone tried ebid.net?
01-29-2013 #1
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Anyone tried ebid.net?
Has anyone tried to sell on ebid.net? I am very tempted because their fees are so much less than ebay. However, I wonder if ebid has enough traffic and I wonder about their customer service?
Has anyone had any good luck on Ebid?
01-30-2013 #2
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Sorry, I have no experience with eBid. I sell on RubyLane and think in general it is a very good service. Anyone else?


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Pike River Coal Mine Royal Commission Findings Released
New Zealand Prime Minister John Key talks to the media at a press... News PhotoBeehive - New Zealand,Government,Horizontal,Human Interest,John Key,New Zealand,Politics,Press Conference,Prime Minister,Talking,The Media,Waist Up,Wellington - New ZealandPhotographer Hagen HopkinsCollection: Getty Images News 2012 Getty ImagesWELLINGTON, NEW ZEALAND - NOVEMBER 05: New Zealand Prime Minister John Key talks to the media at a press conference at The Beehive, New Zealand Parliament Buildings on November 5, 2012 in Wellington, New Zealand. The findings of the royal commission into New Zealand's Pike River mine disaster have been made public today. It has been almost two years since the explosions at the coal mine on the South Island, killing 29 people. (Photo by Hagen Hopkins/Getty Images)


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Create your very own wintertime town with the Christmas Village cartridge! Not only does the cartridge contain cuts for a more modern 3D village, but it also includes cuts for a 3D nativity setting. You can decorate like never before this holiday season! Use the latest Cricut® cartridges to create unique and engaging designs for every occasion......
Click here to read product details
This was one of the first cartridges I purchased. I created such a beautiful scene which tells the story of Christmas Day. Everybody was so touched by it, because it reminded them what the true meaning of Christmas is. I used pretty dark colors, as it was night, but Mary, Joseph and baby Jesus were lighter and I used a small light behind them to give some lighting to that specific scene. I also put lights behind the buildings, in different colors, and one behind the star. It was just gorgeous. I just love how it came out, and my family and friends do too. All of them wanted me to do one for each of them. I really recommend this cartridge if you really want to bring "the Spirit of Christmas" to your home.
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Results tagged "IAB Job Analysis" from IABlog
The Air Up Here
"It's like reflecting on oxygen. You never consciously think about it, but you know it's always right there."
This is how one digital media sales exec described the seemingly simple task of mapping and documenting all the knowledge, skills, and capabilities that he uses in the daily doing of his job. Eight of his counterparts from other digital media companies nodded in vigorous agreement, realizing after just a few moments together how challenging it would be to pinpoint exactly what it is they do and know that makes them successful at their jobs.
The occasion for this meta-reflection was a Job / Task Analysis workshop, held at the IAB Ad Lab in December. The 2.5 day engagement was the first in a series of four workshops established to develop a new industry-wide certification exam for digital media sales professionals. The certification exam, due to go live in late summer, will establish minimum standards identifying what digital media salespeople ought to know in order to do their jobs effectively. This is an ambitious, but necessary, endeavor given the constant knowledge gaps created by the dynamic nature of digital marketing. Created by subject matter experts in our industry, facilitated by a professional certification development company, and sponsored by the IAB, the program will impartially guide industry-wide professional training needs and help hiring managers qualify candidates for roles.
A bit daunted, but excited, at the challenge of expounding on the merits of oxygen to All Who Breathe, the Job / Task Analysis team got to work. The nine-person think tank represented a wide cross-section of the US digital media industry, from a range of brands, company types, sizes, platforms, and geographies. What they shared was a common knowledge of digital media sales and a passion for helping to move the industry forward.
And move forward they did. By the third day, digital media jargon, abbreviations, and mathematics equations long taken for granted as general knowledge spilled from their lips as casually as … well, as casually as the oxygen rushed in to fuel their next brilliant observation. Participants were astounded to discover not only how much endemic knowledge they tapped into each day, but also how much of that know-how was shared across the industry, despite where each of them came from.
The output of this session will become the content outline for the certification exam. But first, their findings are being validated by the rest of the industry—that means you—through an online survey. All digital media sales teams should take this short survey to ensure we're all breathing the same air. The link will be open until January 29, 2012.
About the Author
Stacy Smollin Schwartz
Stacy Smollin Schwartz is a consultant to the IAB and is project manager of its new Digital Media Sales Certification program.


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Patient Education is a key component in our comprehensive continuum of care, and how we help you maximize your success after total joint replacement surgery. If you are thinking about having a Total Joint Replacement or are scheduled to have a Total Joint Replacement, you and your family are invited to learn more about the process before, during and after surgery.
Nazareth Hospital helps you become an active partner in your healthcare by preparing you for joint repalcement and recovery. Nazareth is nationally certified for hip and knee replacement by The Joint Commission and has been designated a Blue Center of Distinction for Knee and Hip Replacement by Independence Blue Cross.
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Edd wrote:I'm guessing PG logged in as Auntie BB for some nefarious purpose (like rigging the vote or spamming) and discovered that someone else had already done so.
Ubi Dubium wrote:So PG has now outed himself as one of the perpetrators of Auntie BB,
Ubi Dubium wrote:and simultaneously failed to sway the vote the way he wants it.
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NEWPORT–The North Country boys basketball team put together arguably their best effort of the season, as they played a complete thirty-two minutes of basketball to pick up a 64-44 win over Missisquoi Valley Union on Saturday afternoon.
"I thought we were very aggressive today," said NCU coach Ed Duncan. "We were after every ball, every rebound and I thought we moved the ball well, we had good looks at the basket and everything was falling for us."
For the full story, see the Express on 1-13-14.


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You want a bridge camera for between u00a3150 and u00a3300. Here is a list of our favourite bridge cameras with a price of u00a3150 to u00a3300
Bridge cameras for between £150 and £300:
Fujifilm Finepix S2500HD
Although there are a couple of issues with image quality the S2500HD still performs a lot better than can be expected of a superzoom model, and has some useful features besides.
Change selection
Nikon L110
The Nikon Coolpix L110 is a winner for the price. While image quality perhaps isn't its sweetest spot, there's no denying that an easy to use point-and-shoot with a 15x optical zoom for under £200 is a decent buy.
Panasonic DMC-FZ38
The Panasonic Lumix FZ38 is a top-performing superzoom compact at an affordable price point. In fact, for the money, you'd be stretched to find any better. The lens is great, as are the controls, and the overall feature set – including a wide-ranging 27-486mm zoom – successfully caters for the beginner right through to more advanced photographer.
What bridge camera to buy, related articles:
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May the Light of Love and Life shine brightly in your heart. Blessed Christmas Greetings! "Jesus spoke to them, saying, 'I am the light of the world. Whoever follows me will never walk in darkness but will have the light of life.'" —John 8:12
Heavenly light illuminates a little donkey, whose inspirational tale brings a message of perseverance and hope to all who receive your greeting this Christmas.
Glossy card stock single folds to 3 3⁄4 x 8 3⁄4"; white envelopes included.
Personalization: Specify names as they are to be printed on your cards.
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I would buy this again and again!
By Dana Lou
from Enid, OK
About Me Budget Shopper
Comments about Little Donkey Christmas Card Set of 20:
This explains who brought Mary to Bethlehem to have Baby Jesus!
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Little Donkey Christmas card
By Marge
from Delran, NJ
About Me Midrange Shopper
Inspire others
Thank you for this beautiful card.
By In memory of Ebenezer the donkey
from Kansas City, MO
A great reminder that the careful and sweet donkey was chosen to carry Mary to Bethlehem. A donkey was there at His birth and death - thus the reason for the symbol of the cross on the donkey's back.
By none
from SCHENECTADY, NY
Little Donkey but big bang
By Pam
from Emory, TX
About Me High-end Shopper
Wonderfully written, what a charming story. Have received more comments about this card than any I've ever sent out. No one ever thinks of the "Little Donkey" that carried Mary and Jesus. Beautiful
Beautiful Quality Cards
By Tina @ Glory Acres Ranch
from Quinlan, Tx
Little Donkey Christmas cards are so very special, just love them & our name was printed perfect. Also I received them very fast. I recommend them!!!
Great Christmas Card
By puddin
from Madill, Oklahoma
Great card for christmas. Has a real good messag. We have burrors also so great for us.
I love this "Donkey" card
By Bear Collector
from Leon, WV
This is one great Christmas card! Not only is it a high quality product but it is a good deal. I just love it.
One of the prettiest cards you offer!!!!
By Angel
from Cripple Creek, Va.
My husband and I own Donkey's and they are such precious animals. The cards remind me of Mary and Jesus. Such sweet cards with the story of the Donkey carrying Mary to Nazareth. Very good quality paper and color. I get lots of compliments on the cards I order from Miles Kimball.
Perfect holiday message
By Ohio RN
from Ohio
Beautiful card depicting the true meaning of Christmas with also showing the true value of animals in our lives! A beautifully written card, I got so many compliments last year when I sent this card to all my family and friends!


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October 1, 2014SU Honors Student Participates in National Undergraduate Research Program
April 3, 2014SU Honors Student Selected for The Harrisburg Internship SemesterFebruary 17, 2014SU Honors Students Continue International Service-Learning Project
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The Honors Program curriculum is designed to create an active, engaged community of lifelong learners. Honors courses are distinguished by their elevated levels of energy, participation, motivation, and expectations on the part of Honors faculty and students.
Honors classes are limited to 20-25 students to provide greater opportunities for students to interact with faculty and their peers. Smaller class sizes allow Honors faculty and students to focus on innovative active-learning strategies (such as debates, discussions, simulations, and explorations) that provide appropriate academic challenges for motivated, high-ability students.
Faculty have the opportunity to teach a variety of courses in the Honors Program, including Honors general education courses, interdisciplinary seminars, core seminars, and the Honors Colloquium, the Honors Program's capstone seminar. (See descriptions below.) If you are interested in teaching a course in the Honors Program, please contact Dr. Kim Klein, Honors Program director, at firstname.lastname@example.com.
The Honors Program offers at least nine Honors general education courses each semester. If you currently teach a general education course and are interested in teaching an Honors general education course, please review the following guidelines:
Honors interdisciplinary seminars are explorations of specific topics designed to demonstrate the interconnectedness of academic disciplines and promote interdisciplinary analysis and problem-solving. The Honors Program Advisory Board distributes the following annual request for Honors interdisciplinary seminar proposals to all faculty members.
The Honors Program also offers core courses in business and education as Honors seminars. The following core courses are regularly offered through the Honors Program:
The Honors Colloquium is one of the capstone options for students in the Honors Program. Students in the Honors Colloquium design and execute a major interdisciplinary service-learning project, and they present the results of their project at local and national conferences. Recent projects have included:
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Product Details
Dodge Durango 2008, 57 Series FIPK Generation II Air Intake System by K&N®. This kit improves airflow into your engine. It includes a K&N air filter and a custom designed air intake tube. The K&N filter increases the airflow and the intake tube smoothes that airflow into the engine. The result is more horsepower and torque, and better acceleration you can feel. Replacement Filter # RC-5138. Use with Pre-Filter # 22-8049DK.
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The K&N 57 Series Generation II Air Intake Kit improves intake airflow from the air filter all the way to the throttle body. The system starts with the world famous K&N high flow air filter. K&N uses the largest conical shaped air filter that will fit in the engine compartment. The large increase in filter area over the stock airbox filter results in a huge increase in airflow and a greater capacity to capture and hold dirt.
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Every Customer can leave a review about our service and the product that was purchased. In order to leave your review for your new product, please follow the link in the email you receive after completing your purchase. You can rate appearance, ease of installation, price/value and product quality.K&N® - 57 Series FIPK Generation II Air Intake SystemAverage Rating: 4.4 of 5APPEARANCEEASE OF INSTALLATIONPRICE/VALUEQUALITYAll K&N Reviews(4.3)APPEARANCEEASE OF INSTALLATIONPRICE/VALUEQUALITY2005 Dodge Durango | Posted by Chris | (Hellertown, PA)
Noticed an increase in acceleration. Better gas mileage, cause we All need that nowadays.8 people found this review helpful.Was this review helpful for you? YesNoShare this review:(4.5)APPEARANCEEASE OF INSTALLATIONPRICE/VALUEQUALITY2005 Dodge Durango | Posted by Doug | (Springfield, MO)
This is a great intake. I installed this on my 05 Durango Hemi in about 2 hours. Very simple install with minimal hand tools. My Durango has an incredible, throaty sound when opening up the throttle. I'm getting much better gas mileage now.7 people found this review helpful.Was this review helpful for you? YesNoShare this review:
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Our huge database is regularly cross-checked to keep it current and optimized. At times, our thoroughness makes our data even more accurate than our suppliers! This rigorous process means that you can always order with confidence.


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Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity (Peri-Op)
Recruitment status was Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Previous studies have demonstrated that patients who undergo surgery while they under general anesthesia have fewer wound infections if they receive higher concentrations of oxygen but this has never been studied in women who are undergoing cesarean section. We plan to randomize women who are undergoing cesarean to receive either standard of care oxygen flow through a nasal cannula during their cesarean section only or a higher concentration of oxygen than they would typically receive through a face mask. Women will receive this therapy during their cesarean and for 2 hours afterwards. We will follow them after their surgery for evidence of infection either in their wound or their uterus.
Cesarean Section
Surgical Wound Infection
Other: 80% inhaled oxygen via non-rebreather mask
Other: 30% inhaled oxygen via nasal cannula
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
|Official Title:
|Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity
- Wound Infection [ Time Frame: 4 weeks post-cesarean ] [ Designated as safety issue: No ]
- Endometritis [ Time Frame: 4 weeks post-cesarean ] [ Designated as safety issue: No ]
- Maternal temperature greater than 38 degrees after the first 24 hours post-op [ Time Frame: 4 weeks ] [ Designated as safety issue: No ]
- Antibiotic usage greater than 24 hours post-op [ Time Frame: 4 weeks ] [ Designated as safety issue: No ]
- Wound opening greater than one centimeter for any cause [ Time Frame: 4 weeks ] [ Designated as safety issue: No ]
- Maternal hospital readmission [ Time Frame: 4 weeks ] [ Designated as safety issue: No ]
|Estimated Enrollment:
|Study Start Date:
|February 2008
|Estimated Primary Completion Date:
|December 2009 (Final data collection date for primary outcome measure)
|Assigned Interventions
Active Comparator: 1
10 liters of oxygen via non re-breather mask during cesarean section and up to two hours post-operatively
Other: 80% inhaled oxygen via non-rebreather mask
Patients randomized to treatment group will receive 80% inhaled oxygen via a non-rebreather face mask during their cesarean section and for 2 hours afterwards.
Active Comparator: 2
2 liters of oxygen via nasal cannula (standard of care) during cesarean section only
Other: 30% inhaled oxygen via nasal cannula
Patients randomized to treatment group will receive 30% inhaled oxygen via a nasal cannula (standard of care)during their cesarean section.
|Ages Eligible for Study:
|12 Years to 50 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Pregnant patients undergoing a scheduled or unscheduled cesarean section with regional anesthesia
Exclusion Criteria:
- Urgent fetal or maternal indications for cesarean section precluding informed consent
- Evidence of extrauterine infection
- HIV infection
- Chronic steroid or other immunosuppressant use
- Patients undergoing general anesthesia
Please refer to this study by its ClinicalTrials.gov identifier: NCT00603603
|Contact: David Stamilio, M.D., M.S.C.E.
|(314) 747-6788
|Contact: Patricia Fogertey, R.N., M.S.N.
|(314) 362-5362
|United States, Missouri
|Barnes Jewish Hospital/Washington University School. of Medicine
|St. Louis, Missouri, United States, 63110
|Contact: Patty Fogertey, RN firstname.lastname@example.com
|Principal Investigator: David Stamilio, M.D., M.S.C.E.
|Sub-Investigator: Christina Scifres, M.D.
|Principal Investigator:
|David Stamilio, M.D.
|Washington University Department of Obstetrics and Gynecology
No publications provided
|Responsible Party:
|David Stamilio, M.D., M.S.C.E., Washington University Department of Obstetrics and Gynecology
|ClinicalTrials.gov Identifier:
|NCT00603603 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 17, 2008
|Last Updated:
|May 26, 2009
|Health Authority:
|United States: Institutional Review Board
Keywords provided by Washington University School of Medicine:
Surg Wound Infect
Additional relevant MeSH terms:
Uterine Diseases
Surgical Wound Infection
Wound Infection
Adnexal Diseases
Genital Diseases, Female
Pathologic Processes
Pelvic Inflammatory Disease
Postoperative Complications
Wounds and Injuries
ClinicalTrials.gov processed this record on October 09, 2015


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SEASON RENEWALS ARRIVE: Isles Raising Season Subscriber Prices, Attempting to Offset Cost With JT91
The last few years have been up and down when it comes to the Islanders and their season ticket pricing. Two years ago season ticket renewals that went out around this same time hit mailboxes with a loud thud. The team was asking for interest payments (!) on plans not paid by April 1. Fans voiced their displeasure and won. Wrote Chris Botta:
Presented with invoices for 2010-11 season tickets and an April 1 deadline before interest charges would kick in, several Islanders full season ticket package owners told the team they were mad as hell and would not take it any longer. Just as strong as the pushback, Islanders executives had to be concerned about the countless season subscribers they did not hear from in the days leading up to the full-payment deadline.
So with three days to spare, the franchise has relented – a victory for common sense and one of the most passionate fanbases in professional sports.
A year later and led by Michael Picker, the team did an impressive roll back on some seating areas dropping some $90 seats to $72 and others seeing $6 per game drops. Other sections where demand was higher did not get such price breaks. This was on the heels of a season where ticket sales bottomed out hard, thanks to a horrific losing streak in November.
According to ESPN, the Islanders averaged 11,059 fans per game last year, down from 12,735 in 2009-10 and the lowest number for the team since ESPN has tracked attendance.
So, it's March again and renewal letters began to hit mailboxes this week after the team lost leads to two local rivals over the weekend; the Devils on Saturday and Rangers on Sunday. Make no mistake, the sales reps at the Coliseum were hoping that the team held on to win at the Garden on Sunday night. The timing of these letters hitting mailboxes is certainly poor and the tone of phone calls this week would have been better with a win over the Rangers (but everything is always better with a win over the Rangers).
The letters — an example to your right with names removed to protect the innocent — starts talking about the playoff chase and is dated March 9th. Point Blank hasn't focused on the playoff push in a couple weeks, but by no means does that mean those doing otherwise were incorrect. Regardless, while the letters were sitting in the post office over the weekend, the Islanders slipped further out and fell to 10 points back with 13 games to go thanks to the two tough losses against rivals. That's not going to please a lot of recipients regardless of the pricing and that's also quite also a gamble — picking a big weekend with two games against local rivals to send out renewals. Based on the reactions around twitter and always-on-top-of-everything forum IslanderMania, season subscribers are not pleased.
To the team's credit, they're not doing this and offering nothing in return. John Tavares, the unbelievably marketable player that he is, will personally sign a jersey for you and shake your hand if you pay by April 16th, right along with your taxes. For those not willing to pay up quite so quickly, you can choose an installment plan and still get a signed jersey from any player you choose. But it's quite clear from the estimates that I've been told, fans will still be paying for those jerseys.
"My family has had [tickets] for almost 20 years," one with seats in the 200s told me. "Sadly this is probably the last straw." That person saw an increase of $420 for the pair of seats they have, pushing the total bill to over $8,000. Another season ticket holder told me they were handed a $5 price increase for each of two seats in the lower bowl, also totaling a $420 increase. Another subscriber on the red line in the upper bowl saw a smaller increase of $2 per game, totaling $168 for two seats. There are others with mostly similar figures and while I've only taken a small sample, I have yet to run into someone who has not had any sort of an increase.
The jerseys are a nice item, for sure. But they don't do a lot to offset the biggest problems, in consumers' wallets and on the Coliseum ice. The team is on pace for 78 points this year, which would only be five better than last year's final total. After some wins and exciting games at the Coliseum in the second half of last season, more fans bought in this season. Now we're seeing the effects of the uptick in demand with an uptick in price but the problem is that the on-ice product is roughly the same. Fans are frustrated and it certainly looks like some will not be willing to pay the extra ante.


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Please read the latest news from the Fairtrade International communications office. You can also follow us with your RSS reader. For more general information and other resources, click here.
Fairtrade Czech Republic Extends its Activities to Slovakia02 April 2014
Organization name change to Fairtrade Czech Republic and Slovakia[more]
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The confectionery company to purchase 20,000 MT of Fairtrade cocoa over 3 years under new Fairtrade Cocoa Program, thousands of Ivorian cocoa farmers to benefit[more]
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Fairtrade recognizes the vital role of women in agriculture on International Women's Day[more]
Fairtrade seeks to unlock the power of local leadership as an important key to eliminating child labour05 March 2014
An article by Anita Sheth, the Senior Advisor on Social Compliance and Development at Fairtrade International. Read more about Fairtrade's perspective on child rights here. In June 2013, Fairtrade International passed a...[more]
Manifesto of the Poor: Fairtrade Co-Founder Releases New Book28 February 2014
Twenty-five years ago Frans Van der Hoff and friends kicked off the Fairtrade movement bringing the first bags of Max Havelaar coffee to shelves in the Netherlands. The movement they started, alongside the farmers of UCIRI in...[more]
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Director of Fairtrade banana cooperative named Chair of Fairtrade International Board, first time a Fairtrade producer holds the position.[more]
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Midwest Living Review
Having been in the restaurant business for decades, Dot Rawlins, owner of the 1865 Alexandria House B&B, whips up a killer gourmet breakfast for guests staying in her Victorian home two blocks from the historic Woodstock square. Enjoy a breakfast of homemade sweet breads, fresh fruit salad, and a fluffy egg, cheese and ham sandwich in the bay window nook surrounded by Dot's treasures. The eclectic decor is a mix of Dot's favorite flea-market finds, diverse pieces she's collected on world travels and some pretty good artwork she's painted. Animal print fabrics and heirloom antiques pepper the guest sitting room, formal dining room and the four upstairs guest rooms. Rates are $95 to $125 a night (free Wi-Fi). Just like staying at your parent's house, bank on really good home cooking and sometimes hearing their favorite television show in your bedroom upstairs (the owner's TV den is below the king bedroom).


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Officials in Michigan have finally ended a lucrative scam: attending college and collecting food stamps on the grounds of need. College kids in Michigan have been cheating the taxpayers by claiming they were too poor to buy food.
No longer. The Detroit News reported on Monday that Human Service Director Maura Corrigan has tossed 30,000 college students off the food dole, which will save the state $75 million annually.
Naturally, food stamp devotees want as many college students on the program as possible. But almost everyone, including Kwame Kilpatrick, the former Mayor of Detroit, knows that using food stamps while in college is a scam on the taxpayers.
Click here to read the entire article.


text: Returning undergraduate students are able to indicate a gender neutral assignment preference during Reapplication. This will allow students to form room selection groups and/or select spaces without regard to legal sex. Please read the FAQs below to learn more about this option that is being offered in the Undergraduate Reapplication and Room Selection process.


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The country is still shocked and saddened over the Boston bombing which left three dead and hundreds injured.
On Tuesday, Mark Wahlberg stopped by "Jimmy Kimmel Live" to promote his latest flick "Pain & Gain," but also opened up about the tragedy which took place in his hometown.
Check out the clip above to see what the Boston native said about how his family is doing and if he knows anyone affected by the horrific act of terror.
The actor asked that everyone "please pray for Boston," adding, "and we have to do everything we can to protect our women and children, our people in the country."
After opening up about the bombings, Wahlberg concluded "It's a crazy world we're living in," he sighed. Unfortunately, we have to agree with his sentiments.
Our thoughts and prayers are with everyone affected by the bombings.
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Desktop image
The desktop image allows you to try Kubuntu-Active without changing your computer at all, and at your option to install it permanently later. This type of image is what most people will want to use. You will need at least 384MiB of RAM to install from this image.
There is one image available:
- PC (Intel x86) desktop image
- For almost all PCs. This includes most machines with Intel/AMD/etc type processors and almost all computers that run Microsoft Windows, as well as newer Apple Macintosh systems based on Intel processors. Choose this if you are at all unsure.
A full list of available files, including BitTorrent files, can be found below.
If you need help burning these images to disk, see the Image Burning Guide.
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Parent Directory - MD5SUMS 18-Oct-2012 11:36 72 MD5SUMS-metalink 18-Oct-2012 11:36 77 MD5SUMS-metalink.gpg 18-Oct-2012 11:36 198 MD5SUMS.gpg 18-Oct-2012 11:36 198 SHA1SUMS 18-Oct-2012 11:36 80 SHA1SUMS.gpg 18-Oct-2012 11:36 198 SHA256SUMS 18-Oct-2012 11:36 104 SHA256SUMS.gpg 18-Oct-2012 11:36 198 kubuntu-active-12.10-desktop-i386.iso 17-Oct-2012 17:28 1.0G Desktop image for PC (Intel x86) computers (standard download) kubuntu-active-12.10-desktop-i386.iso.torrent 18-Oct-2012 11:36 40K Desktop image for PC (Intel x86) computers (BitTorrent download) kubuntu-active-12.10-desktop-i386.iso.zsync 18-Oct-2012 11:36 2.0M Desktop image for PC (Intel x86) computers (zsync metafile) kubuntu-active-12.10-desktop-i386.list 17-Oct-2012 17:28 2.8K Desktop image for PC (Intel x86) computers (file listing) kubuntu-active-12.10-desktop-i386.manifest 17-Oct-2012 17:26 40K Desktop image for PC (Intel x86) computers (contents of live filesystem) kubuntu-active-12.10-desktop-i386.metalink 18-Oct-2012 11:36 1.0K


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|The Expository Genius of John Calvin Media
|Image: Front Cover (high res)
|Image: Back Cover (high res)
He has enlightened these truths for the church now
This is so vital to todays churches who will not hear the pure exposed Word of God. It is sad to have pastors in the pulpit who are ashamed to proclaim the innerancy of Scripture to the sheep who need it. We thank Sovereign God for a man such as this to be bold enough to expose such truth. Amen, and amen. Mobile, Alabama
Refocuses your Preaching
As I read the book I found that it caused me to take a hard look at my own preaching. I was reminded that God's Word is the focus rather than some skillfully crafted sermon that is pleasing to the ears yet lacks true Biblical meat. May God's Word be THE central focus of our ministry.
Remarkably forgettable
I really wanted to appreciate this book. I picked it up, read some, and put it down. Then I picked it up again hoping that my second attempt would give me a fresh perspective. This time I managed to read it all in one sitting (during a flight across the Atlantic from the Sates to Ireland). I am sad to report that this book tells us far more about the personality of the author than about the mind and genius of John Calvin. The real Calvin, from what I have read of his work, was thorough, clear-sighted, aware of his detractors, loved his congregation(s) and was first and foremost committed to loving God. He was also aware that he was a wretched sinner (not just theoretically, but in reality). Whereas, the Calvin presented in this book is a polished up version of what most pastors aspire to be - a performing rhetorician who pretends he knows of what he speaks and attempts to "edify" his listeners with a smattering of religious jargon and a few references to certain obscure words found in the original languages. If you truly desire to be a "great" preacher, don't waste your time reading this. Get a good systematic theology (e.g. Berkhoff), outline the books of the Bible as you read them, memorize lengthy passages on which you can meditate while you cut the lawn ... and by all means, buy and study a good book on Logic. There is no other way to become a "valuable" preacher than to devote a few decades to learning Scripture and learning how to think clearly. Don't read about how others excelled at baseball - get out there and get down on your hands and knees so you can taste the clay.
A call to true ministry.
What a great book. In this time of "seeker friendly and name it and claim it", this is a fresh call to Biblical authority and ministry as well. A must for the serious student of the Word as well as anyone who desires to share God's word in a pure and undefiled manner...as well to God's glory alone. Thank you for this extremely important work.
Love This Book!
Fantastic meditation on Calvin's preaching. A must read for this generation of preachers. Get a copy for your pastor. If he reads it, you will get the benefit!


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Andrea Mandell, USA TODAY
Cory Monteith, 31, died on Saturday at the Fairmont Pacific Rim hotel in downtown Vancouver.
"We are so saddened to confirm that the reports on the death of Cory Monteith are accurate. We are in shock and mourning this tragic loss," confirms his publicist, Melissa Kates, to USA TODAY.
Word began to spread on Twitter at roughly 1 a.m. ET that theGleestar had passed away due to an apparent drug overdose. CTV British Columbia, a local news station based in Vancouver, appeared to report the news first.
MORE:Celeb reaction
Vancouver police said in a news conference on Saturday evening Monteith was found at noon on the hotel's 21st floor. He checked into the hotel on July 6, and was expected to check out on Saturday. When Monteith missed his checkout time at noon, hotel staff went to his room and found him.
"An autopsy is scheduled for Monday," said Vancouver Acting Police Chief Doug LePard. "The coroner will be determining the next steps with respect to establishing cause of death, but all indications are that there was no foul play."
Monteith voluntarilyadmitted himselfinto a rehab facility in March for substance addiction. In late April, the star completed the program and checked out. His last public outing was with his girlfriend andGleeco-star Lea Michele at the Chrysalis Butterfly Ball on June 8.
Monteith even joined in on theSharknadosocial media phenomenon on July 12, asking his 1.5 million followers what exactly "a Sharknado" was.
The actor shot to fame whenGleelaunched in 2009, playing lead hunk and football player-turned-warbler Finn Hudson.
Monteith toldParademagazine in 2011 he was "out of control" as a teen. He revealed that at age 13, he drank, smoked pot and skipped school in Victoria, British Columbia, after his parents divorced. By 16, he said, his drug use had escalated. He was "doing anything and everything, as much as possible." At 19, he entered rehab for the first time.
The actor had been dating Michele for more than a year. The two looked happy together at the June gala, and previously Michele issued a statement of support toPeoplewhen he entered rehab in April. "I love and support Cory and will stand by him through this. I am grateful and proud he made this decision," she told the magazine.
Michele's rep, Jillian Roscoe, issued this statement early Sunday: "We ask that everyone kindly respect Lea's privacy during this devastating time."
It is unclear when the couple was last together. Michele posted vacation pictures from a girls' trip to Cabo San Lucas on Twitter over the July 4 holiday. On July 1, she attended a Beyonce concert in L.A. and posted lyrics from one of singer's love songs,1 +1on her account, with a heart.
"I saw him a few weeks ago in NY, looking so happy. heartbreaking..." wrote Sophia Bush on Twitter.
TheGleecast, including Monteith, assembled as recently as June 28 to shoot promotional photos for the upcoming Season 5 of the Fox series. Adam Shankman, a frequentGleedirector, reacted the the news early Sunday morning.
"Goodbye my amazing and beautiful friend," wrote Shankman on Twitter. "The lights in my world just grew dimmer. The world just lost one of our best. I love u so much..." Kristin Chenoweth, who frequently guest-starred on the show, wrote, "RIP Cory Montieth. You will be loved. Always."
His co-star Mark Salling offered just one word via social media as the news broke.
It was simply "no."