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- Northern New York Newspapers
- Watertown
- Ogdensburg
- Massena-Potsdam
- Lowville
- Carthage
- Malone
- NNY Business
- NNY Living
- NNY Ads
An Adams teen was sentenced Friday in Jefferson County Court to 10 years probation for repeatedly sexually abusing three children.
Dakota J. Weaver, 18, whose last known address was 35 S. Main St., Apt. 134, also was sentenced to an unspecified amount of time served at the Metro-Jefferson Public Safety Building and was ordered to register with the state as a Level 3 sex offender for Oct. 23 guilty pleas to three counts of course of sexual conduct against a child.
He admitted that he molested three children under the ages of 10 between March 31, 2009, and March 31, 2011, in Watertown.
In other court activity Friday:
Zachary S. Cushman, 21, Watertown, was sentenced to a year in the PSB for a Dec. 3 guilty plea to fourth-degree criminal possession of a weapon and an admission that he violated probation. He admitted that on July 17 he possessed brass knuckles on North Rutland Street. It was illegal for him to have the weapon because of previous criminal convictions of second-degree criminal trespass in November 2009 and third-degree burglary in August 2010. Information about why he was serving probation was not available from the court, but he violated probation by being convicted of the new crime.
Robert G. Williams, 26, of 86 Public Square, Apt. 202, was sentenced to five days at the PSB, five years probation and a $1,500 fine for a Nov. 30 guilty plea to felony driving while intoxicated. He admitted that he drove while intoxicated April 21 on County Route 42 in the town of Wilna.
He also had his drivers license revoked and was ordered to install an ignition interlock device on any vehicle he owns or operates.
Jeffrey R. Ashwood, 50, of 215 S. Pleasant St., was sentenced to five years probation for a Sept. 14 guilty plea to third-degree attempted criminal sale of a controlled substance. He admitted that, with another person, he tried to sell cocaine April 9.
Derek C. Gamble, 29, Black River, and his wife, Michelle M. Vebber, 22, were sentenced to three years probation for earlier guilty pleas to petit larceny. They admitted that they cashed $5,000 worth of travelers checks that had been stolen from Mr. Gambles mother, Sheila Vance, Ellisburg.
Plumer D. Reed III, 36, address not available, pleaded guilty to third-degree attempted criminal sale of a controlled substance. He admitted that he sold crack cocaine Oct. 19 within the county.
He is expected to be sentenced March 15 to 3� years in state prison, followed by an additional two years of supervision upon his release. He will serve his sentence in the prison systems Willard Drug Treatment program. If an inmate completes the 90-day program, he serves the remainder of his sentence under parole supervision.
William S. Paluzzi, 21, of 31677 Sandy Hollow Road, Philadelphia, pleaded guilty to third-degree rape. He admitted that on Aug. 4, 2011, he had sexual intercourse with a 23-year-old woman without her consent in the town of Theresa. He is due to be sentenced March 15 to 10 years probation and be required to register with the state as a sex offender.
Garet R. David, 26, Massena, pleaded guilty to second-degree criminal possession of marijuana. He admitted that he possessed 15 pounds of the drug during a March 15 traffic stop on Interstate 81 in the town of Watertown. He is expected to be sentenced April 15 to five years probation.
Brooke E. Staniski, 20, Watertown, pleaded guilty to second-degree attempted burglary. She admitted that, with others, she tried to go into the residence of Jacob J. Traynor on James Street in Clayton and steal cash and heroin. She subsequently was sentenced to time served at the PSB and five years probation.
Omar Ramirez, 22, an inmate at Gouverneur Correctional Facility, pleaded guilty to third-degree assault. He admitted that he punched and injured Victor Carpio in November 2011 while both were incarcerated at Cape Vincent Correctional Facility. He subsequently was sentenced to time served and returned to prison, where he is serving a 3�- to 6-year sentenced imposed in 2010 in Suffolk County on drug charges.
Heather L. Soluri, 30, Watertown, admitted violating probation and was resentenced to 30 days in the PSB. She was serving a sentence of five years probation given her in October 2011 for a felony aggravated DWI conviction. She admitted violated probation by being charged with petit larceny for stealing merchandise from Burlington Coat Factory, Salmon Run Mall.
In court activity Thursday, Brian S. Dick, 43, was sentenced to three to six years imprisonment and ordered to pay $7,522 in restitution for violating conditions of Drug Court, a substance abuse rehabilitation program that is designed to serve as an alternative to incarceration.
He was referred to the program in January 2012 for a guilty plea to third-degree criminal possession of stolen property. State police charged him with possessing gold jewelry valued at more than $7,000 that had been stolen from a town of Lorraine residence.
Information about what led to his Drug Court violation was not available from the court. He was sentenced to prison as a second-felony offender, having pleaded guilty in 2004 to fourth-degree criminal possession of stolen property for having a stolen credit card. He was sentenced to five years probation in that case.
Thousands of readers like you have made Northern New York Newspapers the number one ranked website* for local news and sports coverage in the north country.
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Science Friday® is produced by the Science Friday Initiative, a 501(c)(3) nonprofit organization.
Science Friday® and SciFri® are registered service marks of Science Friday, Inc. Site design by Pentagram; engineering by Mediapolis.
He's flown the space shuttle five times, and performed eight spacewalks to service the Hubble telescope. Now astronaut and astrophysicist John Grunsfeld heads up NASA's Science Mission Directorate, where he manages scientific investigations on the home planet--and beyond.

subset: commoncrawl


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Los Angeles Clippers v Brooklyn Nets
The mascot for the Brooklyn Nets, the BrooklyKnight flies in to score... News PhotoBarclays Center - Brooklyn,Basketball - Sport,Borough - District Type,BrooklyKnight,Brooklyn - New York,Brooklyn Nets - Basketball Team,Full Length,Horizontal,Los Angeles Clippers,Making a Basket,Mascot,Match - Sport,NBA,NBA Pro Basketball,New York City,Scoring,Sport,Taking a Shot - Sport,USAPhotographer Bruce BennettCollection: Getty Images Sport 2012 Getty ImagesNEW YORK, NY - NOVEMBER 23: The mascot for the Brooklyn Nets, the BrooklyKnight flies in to score two during a break in the game between the Brooklyn Nets and the Los Angeles Clippers at the Barclays Center on November 23, 2012 in the Brooklyn borough of New York City. NOTE TO USER: User expressly acknowledges and agrees that, by downloading and/or using this photograph, user is consenting to the terms and conditions of the Getty Images License Agreement. The Nets defeated the Clippers 86-76. (Photo by Bruce Bennett/Getty Images)


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Submission Google develops Master API - Web Intents->
GeneralSecretary writes: "Google is developing an API to allow Web Apps to easily share information with other Web Apps with a unified API. For example there would be a default aPI for sharing things which would work with services like Google+, Twitter, and Facebook using a single predefined API. This is like OLE for the Web."
Link to Original Source
Link to Original Source


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CHICAGO (MarketWatch) — Large multinationals offer an investment avenue to emerging markets that proponents argue has staying power for years to come.
These companies are the world's "global gorillas," beating their chest for investor attention that's been distracted by developed world problems at the expense of emerging market opportunities.
Optimism returns to China property market
Signs of recovery in China's property market send an optimistic signal for the economy in 2013. The WSJ's Tom Orlik explains what measures helped to spur this recent improvement in outlook.
These behemoths boast all-weather management skills and sizable workforces. But don't limit yourself to companies with established-market footholds, longevity and time-tested brands — or even the M&A flurry that's taken over global consumer giants.
This emerging-market theme is about being nimble despite girth. It's about reach, a willingness to look beyond China, India and Brazil (although not to ignore them) to Vietnam, Malaysia, the Philippines, and parts of Africa where cappuccino-craving and smart phone-dialing consumers are queuing up, or will be soon enough.
Destinations operating below this level of consumerism first need infrastructure, food innovation, and mobile bandwidth. In other words, more potential stock opportunities.
"It's the end of the world as we know it, but certainly not the end of the world. We're in a new world that encompasses globalization, changing demographics, and technology," said David Darst, Morgan Stanley Wealth Management's chief investment strategist.
"So ride the demographic wind. Let it push you rather than fight you." Darst and his Morgan Stanley Smith Barney colleagues put "global gorillas" on their 2013 list of trends to watch, in part because emerging markets are expected to generate about 80% of global growth this year, he said.
Maps and goals
For sure, some companies are loosening the fiscal belt. Their pain period is over and they're thinking growth again. That's exciting. But don't go wild over growth without applying the same sniff test you'd give any big company. Is management sound? If the company pays a dividend, is there yield growth? That's why select stock picking among the healthiest multinationals can offset global economic uncertainty.
Below are a handful of themes and investment ideas that might coax you out of the monkey house and into the wild with the global gorillas. Mind the risks, too.
Few surprises here. The global gorillas are essentially the S&P Global 100 Index and the best way for individual investor exposure is iShares S&P Global 100 ETF IOO, -0.37% . The index does give greater weight to energy and financials. Some of its biggest holdings include: Exxon Mobil Corp. XOM, +0.14% , General Electric Co. GE, +0.09% , and U.S.-listed shares of Nestlé S.A. NSRGY, +1.00% and HSBC Holdings PLC US:HBC . Vanguard's Total World Stock Index ETF VT, -0.31% competes in the same space.
Some big companies are already putting more resources in the emerging corners of the globe, where population and growth are beckoning. German cement-maker Putzmeister Holding, for example, has closed its Southern European plants and is building plants in Turkey and Brazil. And last year, Mondelez International Inc. MDLZ, +0.31% formerly part of Kraft, bought U.K.'s Cadbury for, among other reasons, that multinational's reach in many former British colonies.
Some global gorillas are moving to capture emerging healthier lifestyles. Nestlé, for example, has boosted its food portfolio with traditional fare but last year acquired Pfizer Inc.'s nutrition business in a bet on a better-eating world.
Technology of course is one of the global themes few can argue against. As competition heats up for lower-cost smartphones, therein lies opportunity for both manufacturers and stock investors. For instance, Samsung, in pricing its smartphone below that of Apple Inc. AAPL, +0.30% and other rivals, may easily find loyalty among emerging market buyers whose incomes are rising but not on levels matching the developed world. That's one example of nimble product variety and competitive pricing that will prove key to gaining market share in these still fledgling consumer markets.


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Panoramic Aerial View of Chicago from Lake Michigan, Illinois Photographic Print on Canvas
Limited Edition '2 Blondes' by J Coleman Miller Photographic Print on Wrapped Canvas
Snowtime 6.3' Green Pre-Lit Alaskan Spruce Artificial Christmas Tree with 350 Warm White LEDs
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Weights & Dimensions
|Base Material: Stainless steel
|Counter Material: Wood
|Wheels: No
|Product Care: Wipe with mild soap & water & must oil butcher block top every 2-3 weeks
|Product Type: Prep Table
|Base Finish: Brushed stainless steel
|Counter Finish: American cherry, varnique finish
|Hardware Finish: Zinc coated
|Solid Wood Construction: Yes
|Style: Contemporary
|Shape: Round
|Stools Included: No
|Stemware Storage: No
|Finished Back: Yes
|Commercial Use: Yes
|Country of Manufacture: United States
|Assembly Required: No
|Additional Parts Required: No
|Product Warranty: 1 year limited warranty on workmanship and material
About the ManufacturerJohn Boos & Co. is the oldest industry in Effingham, Illinois. It has been in business continuously since 1887. Conrad Boos Sr. founded the business in 1887 and named it for his son, John. For many years he worked out of the blacksmith shop, which was located at what is now 406 West Jefferson Street in Effingham, Illinois. The wood for his blocks was cut in wooded areas surrounding Effingham and was mostly sycamore lumber. The lumber was processed in his sawmill and sent to his shop for finishing. The plant operated from a blacksmith shop until 1892 and then it moved across town, and began producing the blocks as we know them now.
The blacksmith used a sycamore tree placed on three legs to straighten horseshoes. The wooden block absorbed the shock of the smith's hammer. When the butcher saw the block where the anvil was resting, he realized he could use one in his meat market. So John Boos made him one and the rest is history. In the early days the butcher blocks were built for commercial meat markets. At the turn of the century meat purchased at the local market was not refrigerated or frozen, but hung.
The company currently occupies approximately 150,000 sq.ft. of total production capacity in Effingham, IL and approximately 65,000 sq.ft. of manufacturing capacity in Philipsburg, PA and Suring, WI, which produce wooden school furniture. The company has four dry kilns that will dry up to 210,000 board feet of lumber on a continual basis. There are 140 employees in the Effingham facility. Most of the hardwoods used for manufacturing is shipped from Great Lakes states via truck, while their second largest commodity, stainless steel, comes from steel warehouses and distribution centers in Chicago, Indianapolis, and St.Louis. The company currently is cutting up about five million feet of maple and oak each year.
Current Products & Markets
The wood and metal products are listed with the National Sanitation Foundation, the leader in sanitation agencies for approving equipment to be installed in foodservice and supermarket operations. The products must have approval of various sanitation agencies in order to be accepted by the industry. The stainless steel product group, which continues to expand, now includes stainless steel sinks, shelves, carts, etc. One of the outgrowths of their stainless steel plant and our wood plant is the new Cucina series of foodservice carts made from northern hard rock maple and foodservice grade stainless steel. The product has received instant acceptance from professional, as well as domestic chefs throughout North America. Sales are made through major gourmet catalog companies, as well as foodservice equipment dealers. Mixing the two materials provides John Boos & Co. with a competitive edge as the manufacturing begins and ends in Effingham, IL.
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By RICHARD SHAWSun Advocate publisher
Rising operational costs, lower student enrollment and a growing need for technical training will soon permanently alter the complexion of College of Eastern Utah.
All of the factors led to a perfect educational storm in eastern Utah. Last Thursday, the Utah State Board of Regents decided to merge CEU and the Southeast Applied Technology Center.
Founded in 1938, CEU has primarily been considered an academic institution or a junior college. But CEU has a significant vocational side because of the college's blue collar surroundings.
Until the late 1990s, the school had a viable coal mining training program and several strong vocational programs that were taught at the McDonald Career Center. Students could obtain certificates or pursue an associate's degree in the programs.
But the programs began to change when the CEU administration was altered by hiring a president from outside the local area. Programs like mining were eliminated and vocational education was down played. The custom fit training that had been a function of CEU was separated from the college and became a new type of higher education institution.
SEATC, the newly formed institution, did not have a campus, but operated in rented space or even in businesses that requested educational programs for employees or potential employees.
After the legislature passed a bill in 2001, SEATC and eight similar educational institutions around the state fell under the umbrella of Utah College of Applied Technology.
As a result of demographic changes between baby boomers and younger generations, Utah colleges are seeing trends that have been felt across the nation.
Recently the state office of higher education reported that college enrollment is down as much as a 1,000 students across Utah. About half of the state's higher education institutions are experiencing declining student numbers, while the other half are witnessing increasing enrollments.
CEU was reported to be in the former group ,with a decline of more than 130 students for fall semester 2006 compared to 2005.
Meanwhile, UCAT is gaining in enrollment.
CEU has a campus filled with functional buildings and fewer students.
"The enrollment decline at CEU cannot be sustained at the present rate," said higher education commissioner Richard Kendall during a public meeting last week. "We need to do something to provide a viable, sustainable way of doing things that benefits both colleges."
Last spring, CEU president Ryan Thomas told the state board of higher education that the school would fall $350,000 behind on its budget at the end of the fiscal year on June 30 because of declining enrollment.
During the late 1980s, CEU constructed new dorms in an attempt to attract students out of the area. While the idea initially took off, fewer students have been showing up to occupy the rooms in recent years.
Meanwhile, Carbon and Emery school districts have seen significant declines in the number of students going through the systems as populations grow older. Since about 70 percent of the students at CEU come from the local area, declining enrollment in public schools has impacted the college.
On the other hand, the older population fits into UCAT's mission of custom fit and technical training for people who are working or at the age when they want to start careers.
For younger people, UCAT has provided an alternative for students who may not fit into the regular college programs.
"UCAT is nothing like CEU," said Alice Israelson of Emery County at the public meeting. "My son was brought over to the tech school by rehab and he has succeeded because of it. The program made it so that he could go on to college."
Israelson's son told Kendall and other education officials that, without UCAT, he could have never gone on with his education.
"I was comfortable going there," said Jared Israelson. "I spent a whole year going to classes there and I could have never come onto this campus and done that. Now I have the confidence to come here and take classes."
In recent months, the regents had been studying what to do with two programs, which financially and enrollment-wise seemed to be heading in opposite directions. But combining the two is not an entirely new concept. Ever since the creation of SEATC, CEU has handled many of the tech center's administrative functions.
However, UCAT schools and board view their mission as different because of what they teach and the kinds of students they serve.
The move to combine CEU and SEATC in Carbon County may be only the beginning. According to Kendall, the way Utah has the two systems is an anomaly in the country, not the norm.
"We had a person from the higher education system from the Seattle area visit us recently and she looked at the two tiers of educational systems and wondered what it was," pointed out Kendall at the Monday meeting. "She told me that all those functions were handled by the junior colleges in the area. I have also heard that from others around the country. We are the ones who are operating differently."
The meeting also had attendees who opposed to the change or wanted to consider the possibility for a longer period of time.
"When I wanted to go to school, I didn't want to go to college," said Lisha Israelson. "But after going to the tech school, I then decided I did want to got to CEU and I am here now taking classes."
Ann Evans, director of the Carbon County Chamber of Commerce, pointed out that college is not for everyone and SEATC has offered a viable alternative for many people.
"From the chamber's perspective, not all businesses are looking for someone with a degree," stated Evans. "The ATC has certification programs that businesses can send people through or the individuals can afford to pay for themselves. It provides the flexibility for people like single moms who need to go through school and work at the same time."
Price Mayor Joe Piccolo suggested that, if the merger were to happen, the schools should consider creating a community committee to oversee the process.
One issue raised at the public meeting was the question of how the two higher education institutions' employees would be handled.
Under the CEU program, professors and instructors are compensated based on classes taught and credit hours, while UCAT instructors work based on the 40-hour work week.
With a merger, the differences will have to be rectified and equalized in some way.
Many of the individuals associated with UCAT administration and boards have not been happy about the process in which the merger idea was put together.
Some UCAT representatives feel that the technology college's points of view are being ignored by the decision makers.
"We aren't doing this to save money," said Kendall toward the end of the meeting. "CEU has been doing a lot of the administrative functions for UCAT over the years while they have been leasing space for classes and renting equipment. Together, they can just be more efficient. We don't want to change what UCAT is doing but to find a way to do what both schools do better. The intent of the study was to see if the two schools could work together without competing with each other. We just can't think old school anymore.".


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BANGOR, Maine (NEWS CENTER) -- It's a chance to admire what the outdoors have to offer without having to deal with the cold weather. For the past three days, landscapers have moved their work from outside to inside in preparation for the 2013 Maine Garden Show.
This year's theme is one that we can all relate to. It's 'Our Maine Life,' and landscapers have been busy constructing designs to demonstrate what they feel is Maine life. Trees, flowers, campfires and much more have taken over the floor in the Bangor Auditorium creating a scenic layout with a variety of sights.
Competitors have been working hard since Monday to make sure their designs look like what they had been planning for months.


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|This article needs to be cleaned up to conform to WikiFur style and standards.
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Sexual orientation describes the gender or genders to which an individual feels sexually attracted. The term sexual preference is often used interchangeably, though this term is more broad and broad and includes personal attitudes in between the three most common general categories defined as sexual orientations:
- Heterosexuality (also known as straight) describes exclusive sexual attraction to persons of different gender(s); usually exclusive female attraction to men and vice versa.
- Bisexuality is sexual attraction to two or more genders, or the same and different gender(s).[1]
- Homosexuality (also described as gay) describes exclusive attraction to persons of the same gender
- Pansexuality (also known as omnisexuality) describes attraction to all genders, or without reference to gender
- Asexuality describes a general lack of sexual attraction.[2] Asexuality is often thought of as a spectrum, with orientations on that spectrum including grey-asexuality, meaning experiencing very rare sexual attraction, and demisexuality, experiencing sexual attraction only after a close emotional bond is formed.
Sexual orientation and furry[edit]
Orientation surveys[edit]
- A 2007 University of California at Davis study found that 37.3% of respondents were bisexual, 32.7% heterosexual, 25.5% homosexual, and 8% were uncertain.[3]
- A 2006 FAOD poll showed 25% heterosexual, 20% homosexual, and 55% bisexual (out of 44 polled)[4]
- A Furtopia poll (open 2003 to 2007) stated that 53.4% were heterosexual, 15.5% gay, and 31.1% bisexual out of 885 people polled.[5]
- A poll by Alex Osaki reported that 42.75% were heterosexual, 16.86% were homosexual, 35.29% were bisexual, and 4.71% self-identified as neither.[6]
- Research by Dr. Kathy Gerbasi at Anthrocon 2009 found a significant difference between male and female responses; males were distributed across the Kinsey scale while the females responding only chose from "exclusively heterosexual" to "equally heterosexual and homosexual".[7]
The perception of homosexuality/bisexuality in the furry fandom[edit]
The furry fandom has a larger proportion of non-heterosexual individuals when compared to the general population.[8] A lack of completely reliable survey data exists, though the studies that have been done suggest that the stereotype that many furries are homosexual or bisexual is at least partially true, though not to the large extent it is often suggested.[8] While some furries have suggested various theories as to why this is so, there has yet to be a definitive answer put forth.
Pressed Fur reported that some furries also subscribe to this view.[9] Although he did not advocate the social construct theory, Dr. Alfred Kinsey stated that "Males do not represent two discrete populations, heterosexual and homosexual... The living world is a continuum in each and every one of its aspects."[10] He postulated a scale of sexual preferences from zero to six, zero being exclusively heterosexual.[10]
Rust survey[edit]
There are multiple estimates of the percentage of gays in the furry fandom. It is often thought within the fandom that the number is high, possibly as high as 90%,[8] but polls have shown differences in estimation.
A poll used in The Sociology of Furry Fandom, a 2002 paper by David J. Rust hosted at The Darken Hollow, showed 25% heterosexual, 19% homosexual, and 48% bisexual out of 360 peopled polled.[8] Rust concluded that "Truth be told, there are many more homosexual members of the fandom than in general society."[8]
IFPL poll[edit]
An unscientific poll (of indeterminable date, but before 2005) on the IFPL used the Kinsey scale to rate the measure of homosexuality in respondents:
|Exclusively heterosexual
|Predominately heterosexual, incidentally homosexual
|Predominately heterosexual, more than incidentally homosexual
|Equally heterosexual and homosexual
|Predominately homosexual, more than incidentally heterosexual
|Predominately homosexual, incidentally heterosexual
|Exclusively homosexual
One viable theory involves Mark Merlino, a former chair of ConFurence who co-founded the first furry conventions. Crush Yiff Destroy has suggested that Merlino actively recruited alternative lifestylers into the fandom, and that this influences furry demographics to this day.[11]. Some speculate that the negative social stigma attached to the fandom keeps away heterosexual mundanes who would otherwise feel interested.
David Rust has stated that "The social variations for Furries may seem unusual from a generic, American viewpoint. However, from the position of a group of people who are already predisposed to enjoying anthropomorphic animals, other concepts such as homosexuality... seem somewhat mundane and unimportant by comparison."[8]
- ↑ "What is Bisexuality?" definitions from various bisexual organizations. Retrieved September 21, 2014.
- ↑ Overview on the Asexuality Visibility and Education Network. Retreived September 21, 2014.
- ↑ "Furry Survey Results" from University of California, Davis: Department of Psychology. Published 2007-05-05. Accessed 2007-05-05.
- ↑ FAOD Message Board.
- ↑ Furtopia Message Board retrieved December 19, 2008.
- ↑ Furry Poll Results as of December 30, 2007.
- ↑ Anthrocon 2009 psychological survey team releases preliminary results - GreenReaper, WikiFur News/Flayrah (21 September 2009)
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 The Sociology of Furry Fandom. Retrieved October 19, 2006.
- ↑ "Sitting On the Third Side of the Fence" by Hannah Kincaid from Pressed Fur
- ↑ 10.0 10.1 "Kinsey's Heterosexual-Homosexual Rating Scale" from the Kinsey Institute.
- ↑ "Journey to the Center of Mark Merlino"
See also[edit]
External links[edit]
- Heterosexual
- Bisexual
- Bisexual Furry (bifur) on Steam
- Gay,Furry,and Bi Pride on Facebook
- Bi-Sexual Furry Pride on Facebook
- Furry and Bi. Problem? on Facebook
- Homosexual
- GAY Furry Pride on Facebook
- Gay Furry Pride on Facebook
- Furry Lesbians on Facebook
- Lesbian Furry Hotel on Facebook
- GayFurries on Livejournal
- Lesbian Furs on Livejournal
- Omnisexual
- Pansexual Furrys on Facebook
- Asexual
|This article about an Internet topic is stub - can you improve it?


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EAST PROVIDENCE – There's a distinct reason why only a few folks in these parts are paying attention to the success of the Bishop Keough High girls' hoop team: They've been programmed not to care.
Even the school itself, located just up Smithfield Avenue from a cemetery, is miniscule in student population, often graduating between nine and 14 seniors every June. People realize the Keough administration and teaching staff is huge on religion and academics; they also realize they view athletics as extracurricular activities that merely bolster students' resumes for higher education.
EAST PROVIDENCE – There's a distinct reason why only a few folks in these parts are paying attention to the success of the Bishop Keough High girls' hoop team: They've been programmed not to care.
Even the school itself, located just up Smithfield Avenue from a cemetery, is miniscule in student population, often graduating between nine and 14 seniors every June. People realize the Keough administration and teaching staff is huge on religion and academics; they also realize they view athletics as extracurricular activities that merely bolster students' resumes for higher education.
No question, academic excellence is integral for the girls to gain admittance to the college or university of their dreams, but few if any can play at even an NCAA Division III or NAIA level.
According to John Roque, in his fourth season at the helm of the Koalas' squad, not many within the school itself have recognized exactly what these young ladies have accomplished in that time, but it's more than significant.
When Roque took over in November 2009, he led Keough – almost always considered a pushover athletically – to a 6-12 overall mark. For most private or public institutions, that would be considered either a disaster or just a rebuilding season. For the Koalas, it proved to be a benchmark, as it had snagged more victories than it had enjoyed in no one knows how long.
During the 2010-11 campaign, the Koalas went 11-7 overall, only to drop a special play-in tilt to the state D-III tournament. And, a year ago, Roque's contingent finished 13-7 overall, landing just a triumph shy of competing for the Rhode Island championship.
Then there's this winter: Prior to Saturday night's 51-38 defeat to powerhouse Juanita Sanchez of Providence, Keough sat in grand position to garner a playoff bid for the third straight year, as it had recorded a 6-3 overall mark and 4-3 league record.
Add those numbers up, and – under Roque – this tiny program has produced an overall mark of 36-29.
Even the head coach expressed surprise at that.
"Hey, that's not bad!" he grinned while his team practiced inside Haven United Methodist Church's small basement gymnasium (that courtesy of assistant Jim Hibbert) on Thursday afternoon. "I never thought I'd be approaching that number. Like I said, it's not bad, but we still have a ton of work to do.
"At the beginning of this season, I thought we'd be able to compete with the (upper echelon) Middletowns and Juanita Sanchezes, but I was wrong," he added. "Last year, we had a lot of seniors, but they graduated, and we only had two returning starters coming back (senior swing Suigly Mendoza and sophomore guard Ashley Correa).
"The reality is we're still really young, and I'm thinking they feel the same way as my players in our first year felt. The bottom line is these girls still have talent, but they need to learn how to become more of a team. Each individual needs to concentrate on the team concept, and not their own personal statistics. If they do that, there's no reason to think we can't make another run."
Truth be told, Roque initially didn't take the job when Athletic Director Rick Simard came to him back in 2009.
"I turned it down twice, and I had a lot of reasons," noted Roque, a Central Falls native who has achieved success while coaching youngsters at the Boys & Girls Club of Pawtucket. "The third time, Rick called me and said, 'Coach, this is the last time I'm going to offer it. If you don't take it, I'll have to shut the (hoop) program down.' That was around Thanksgiving.
"It was always my dream to coach a high school team, but I didn't want to coach girls, and I also didn't want to coach at Keough because it was so small," he continued. "I knew athletics weren't a huge priority there. I felt like I didn't want my first job to be with a school where two or three wins a season was OK, where no one apparently cared.
"I also thought I couldn't change the program given the talent pool that was provided. But then a trusted friend told me after I expressed my concerns, 'If you can change it, maybe people will look at that and see how well you've done.' I also felt guilty, because I knew if I didn't take it, the basketball program would fail to exist; that would mean it happened because I was being too selfish."
Two days later, he accepted.
"When I came in, I met with Rick, and he told me, 'Look, I know this isn't your dream job, but – if you can hang in there for a year – it will give me more time to find another coach; that way, I won't have to shut it down,'" Roque stated. "I just said, 'I'll give you more than a year if you let me coach the way I want to coach.
"He asked, 'What do you mean?' and I just told him I wouldn't be happy with two or three wins a season," he added. "I said I'd be miserable, and so would the girls who I planned on coaching. He gave me the impression I didn't know what I was getting myself into."
At his very first practice, he asked a few girls to line up on the perimeter.
"They looked at me and said, 'What's that?'" he offered. "Some of these girls had been on the team for two years, and they didn't know what the perimeter was. That's when I realized, "John, you're in trouble.'"
At campaign's end, after expressing to the athletes that all he wanted them to do was listen and work hard, the Koalas closed at 6-12. He claimed he was downtrodden, "but the parents looked at me like I was 'Coach K' (Duke University's legendary men's mentor Mike Krzyzewski). They were, like, 'What a great season! You should be proud,' but I was miserable. Deep down, I knew I was winning more (games) with 11-12 year-old boys at the Boys & Girls Club."
The following year, in 2010-11, the squad took to the floor with a slight increase in confidence, and it showed with an 11-7 mark.
"It was the first time Keough had won 10 games in … well, it could be forever," Roque said seriously. "I asked if the school had archives, so I could look up if it had before, but apparently, they weren't kept. Anyway, we finished the season tied for the last playoff spot with Juanita Sanchez, so we had a special play-in game.
"Sanchez had beaten us once in triple overtime at their house, and the next time we lost by 11 or 12 at St. Raphael (Academy's Alumni Hall, its home floor for contests). We ended up beating them by 17 at their gym, and, man, that was a tough crowd.
"It was pure jubiliation," he continued with a mammoth smile. "I had been coaching since 1999, but I knew that win was so important for this program. We ended up in the (D-III) quarterfinal against Central, and we had to play them at their place (the relatively new and massive Providence Career & Technical Academy's fieldhouse).
"When we walked inside, the girls were in awe, despite the fact we had played them there before. They saw the scoreboard clock above the mid-court stripe, and some of the looked really nervous, others were nervous but acted like they weren't. God, I even had to catch myself; I thought, 'God, I'm coaching a playoff game – here?'
"Still, before the game started, I thought about Rick and the conversation we had a year earlier, about me being hesitatant to take the job. Now I was thinking, 'I wouldn't trade this for the world!'"
The Koalas trailed the Knights by 11 at halftime, but Roque issued them some reassurance.
"I looked into their eyes, and I saw them wanting to quit; I saw the 'We're not going to be able to do this' look," he said. "I just went, 'You think it's over? I don't. Girls, we've worked way too hard this year to give up now. They're expecting us to quit, roll over. They're in there saying right now, 'They're going to roll over in the second half. They're Keough. They look defeated,' but prove them wrong! We may lose, but we're not going down without a fight. They don't think we belong here. Trust me, we do!'"
Led by Mendoza and then-6-1 junior center Caroline Guzman, the Koalas battled back but eventually dropped a tight 44-40 decision.
Before the opening of the 2011-12 campaign, Roque returned with the same mantra he had been preaching since Day One.
"Mr first year, I told them, 'Ladies, we'll probably lose most of our games, but I don't care about that. We're going to play basketball the right way. We're going to play hard, we're going to swarm the ball and we're going to push back when they push us,'" he recalled. "We're not going to be a doormat anymore.
"I still tell them, 'We don't have our own gym, and we don't have a team bus or a great deal of support, but we do have ourselves. You don't need a ton of talent to work hard. It's a decision you have to make deep down in your soul. You can either go out there and bust your butts, or be lazy and lose by 40. You work hard, and you'll have a chance to win.'"
Keough began the season with three straight losses, despite the fact Guzman was back for her senior year and Roque added to his roster the talented Correa. Still, two came to the usual league stalwarts, Sanchez and Middletown.
The Koalas, though, went on a seven-game win streak, mustered a 12-6 record and finished third in the league. For earning the third seed, they hosted their first-ever playoff tilt.
"That was a big issue because we had no gym on campus, and St. Ray's had already given us all of our home dates," he said. "God bless them, they were able to squeeze us in after changing some things around."
They responded in kind, eking out a 46-43 quarterfinal triumph over Central, the same club it lost to in the state tourney the winter before. In the process, it earned a bid to the semifinal against Middletown at Rhode Island College.
"We were one game away from playing for the state championship," he chuckled. "Little Bishop Keough, can you believe it? I told the girls the same thing: Work hard, do what you do best, and you can succeed."
His mood changed immediately.
"We started off flat, and – at one point during the first half – we had more turnovers than points," he said. "The pressure was just too much. Once the opening tip went up, I felt 1,000 pounds of pressure on my shoulders, and I think the girls sensed it. I blame most of that loss on me because it was a new atmosphere even for me.
"I still told the girls at the break, 'Remember last year at Central, with all the lights and media attention? You can come back because we've done it before. Give yourselves a chance and fight back. We're a better team this year, no doubt!'
"They went out and clawed their way back into it, and we were down four with about three minutes left," he added. "With two (minutes) and change left, I called my last timeout to plan what to do. I said, 'Girls, this is what we've been fighting for. You know what, those girls are scared over there. They're intimidated, they're worried!'
"All of a sudden, I looked up, and one of my seniors was crying, 'This is my last game, and I'm going to miss you guys!' Next thing I know, most of the others were crying, and then the horn sounded (to return to the floor).
"The emotion of it all, it was like someone pulled out a pin and burst our balloon. We were just deflated."
Keough lost the contest by four, but Roque claims the tide is turning. Keough is becoming a winning program, and Mendoza, one of his three-tri-captains with Correa and sophomore Jailyn Gomes (a transfer from Our Lady of Fatima), knows why.
"We both came in the same year, and Coach told us right away he wanted us to become winners; I thought he was nuts!" Mendoza giggled. "I didn't think we had that much talent. I mean, we only have, like, 65 girls in the whole school. We didn't have enough girls to draw from.
"Now we're actually winning, and it blows my mind," she added. "My freshman year, we won six games, and we thought that was special. As each year passed, we've won more, and it's because Coach has taught us what we need to do on the court and how to think off it.
"He's such a good motivator, even when we're losing. He tells us we should never give up because we'd never know how a game would turn out if we really tried … My freshman year, I was really nervous, and I didn't know what to expect, but you learn from Coach how to play more aggressive defense, how to be more intense, how to shoot the ball more accurately. Those little things add up.
"But I still think we need to work better as a team. I think, with me and Ashley, we don't work together as well as we should. It's because of communication; we need to talk more on the court. If we do that, hopefully we'll win even more."
Offered Gomes: "He can be a tough coach ..." As soon as the words left her mouth, she heard Roque yell, "Do something!" then chuckled.
"That's what I mean," she continued. "He puts a lot of pressure on us because he wants us to work hard all the time. He says if we work hard in practice, it'll translate to games. He also tells us never to give up, no matter the situation.
"He's helped me most with my shooting. He's always saying not to push the ball but to let it roll of my fingers, and to use my legs."
Correa indicated she's surprised, but isn't, at Keough's steady improvement the past few years.
"I didn't think we'd be that good my freshman year because people said Keough isn't that good," she said. "Now we're proving them wrong. It feels great, but I want to keep it up. I like winning!
"Still, we're not going to let anything go to our heads; we have to keep working hard, and we have to move the ball more," she added. "That's one area we need to get better. Sometimes, we have people who want to do too much themselves, including myself. We need to trust each other more.
"I don't think we're playing even close to as well as we can. I also think we haven't realized just how far we can go. I do know this: It all comes with hard work."


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Nov 2, 2015
Broadway Sings Sara Bareilles
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|U.S. Biomedical Research 'Unsustainable' Prominent Researchers Warn
|Friday April 11, 2014 @09:45PM
|CSIRO Scientists' Aquaculture Holy Grail: Fish-Free Prawn Food
|Tuesday April 08, 2014 @11:15AM
|For the First Time, Organ Regenerated Inside a Living Animal
|Saturday April 05, 2014 @09:03AM
|Scientist Quits Effort To Live-Blog Stem Cell Generation
|Friday April 04, 2014 @05:33PM
|Cheaper Fuel From Self-Destructing Trees
|Thursday April 03, 2014 @03:07PM
|Single-Celled Organism Converted Into Electronic Oscillator For Bio-Computing
|Tuesday April 01, 2014 @11:53PM
|Threatened Pandemics and Laboratory Escapes: Self-fulfilling Prophecies
|Tuesday April 01, 2014 @11:48PM
|Creating "Homo Minutus" — a Benchtop Human To Test Drugs
|Monday March 31, 2014 @03:01PM
|Ancient Virus DNA Discovery Could Be a Breakthrough In How Diseases Are Treated
|Monday March 24, 2014 @04:56PM
|Scientist Live-Blogs His Lab's Attempts To Generate New Type of Stem Cells
|Sunday March 23, 2014 @07:16PM
|MIT Researcher Enlists Bacteria To Assemble Nanotech Materials
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|Monday February 17, 2014 @09:18PM
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The universe seems neither benign nor hostile, merely indifferent. -- Sagan


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17 U.S. Code § 701 - The Copyright Office: General responsibilities and organization
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(a) All administrative functions and duties under this title, except as otherwise specified, are the responsibility of the Register of Copyrights as director of the Copyright Office of the Library of Congress. The Register of Copyrights, together with the subordinate officers and employees of the Copyright Office, shall be appointed by the Librarian of Congress, and shall act under the Librarian's general direction and supervision.
(b) In addition to the functions and duties set out elsewhere in this chapter, the Register of Copyrights shall perform the following functions:
(1) Advise Congress on national and international issues relating to copyright, other matters arising under this title, and related matters.
(2) Provide information and assistance to Federal departments and agencies and the Judiciary on national and international issues relating to copyright, other matters arising under this title, and related matters.
(3) Participate in meetings of international intergovernmental organizations and meetings with foreign government officials relating to copyright, other matters arising under this title, and related matters, including as a member of United States delegations as authorized by the appropriate Executive branch authority.
(4) Conduct studies and programs regarding copyright, other matters arising under this title, and related matters, the administration of the Copyright Office, or any function vested in the Copyright Office by law, including educational programs conducted cooperatively with foreign intellectual property offices and international intergovernmental organizations.
(c) The Register of Copyrights shall adopt a seal to be used on and after January 1, 1978, to authenticate all certified documents issued by the Copyright Office.
(d) The Register of Copyrights shall make an annual report to the Librarian of Congress of the work and accomplishments of the Copyright Office during the previous fiscal year. The annual report of the Register of Copyrights shall be published separately and as a part of the annual report of the Librarian of Congress.
(e) Except as provided by section 706 (b) and the regulations issued thereunder, all actions taken by the Register of Copyrights under this title are subject to the provisions of the Administrative Procedure Act of June 11, 1946, as amended (c. 324, 60 Stat. 237, title 5, United States Code, Chapter 5, Subchapter II and Chapter 7).
(f) The Register of Copyrights shall be compensated at the rate of pay in effect for level III of the Executive Schedule under section 5314 of title 5. The Librarian of Congress shall establish not more than four positions for Associate Registers of Copyrights, in accordance with the recommendations of the Register of Copyrights. The Librarian shall make appointments to such positions after consultation with the Register of Copyrights. Each Associate Register of Copyrights shall be paid at a rate not to exceed the maximum annual rate of basic pay payable for GS–18 of the General Schedule under section 5332 of title 5.
Source(Pub. L. 94–553, title I, § 101,Oct. 19, 1976, 90 Stat. 2591; Pub. L. 101–319, § 2(b),July 3, 1990, 104 Stat. 290; Pub. L. 105–304, title IV, § 401(a)(2), (b),Oct. 28, 1998, 112 Stat. 2887.)
References in Text
The Administrative Procedure Act of June 11, 1946, referred to in subsec. (e), was repealed and the provisions thereof were reenacted as subchapter II of chapter 5, and chapter 7, of Title 5, Government Organization and Employees, by Pub. L. 89–554, Sept. 6, 1966, 80 Stat. 278.
1998—Subsecs. (b) to (e). Pub. L. 105–304, § 401(b)(1), added subsec. (b) and redesignated former subsecs. (b) to (d) as (c) to (e), respectively. Former subsec. (e) redesignated (f).
Subsec. (f). Pub. L. 105–304redesignated subsec. (e) as (f) and substituted "III" for "IV" and "5314" for "5315" in first sentence.
1990—Subsec. (e). Pub. L. 101–319added subsec. (e).
Effective Date of 1990 Amendment
Pub. L. 101–319, § 5,July 3, 1990, 104 Stat. 291, provided that:
"(a) Effective Date.—The amendments made by this Act [amending this section and section 802 of this title and sections 5315 and 5316 of Title 5, Government Organization and Employees, and enacting provisions set out as a note under section 101 of this title] shall take effect on the date of the enactment of this Act [July 3, 1990].
"(b) Budget Act.—Any new spending authority (within the meaning of section 401 of the Congressional Budget Act of 1974 [2 U.S.C. 651]) which is provided under this Act shall be effective for any fiscal year only to the extent or in such amounts as are provided in appropriations Acts."
References in Other Laws to GS–16, 17, or 18 Pay Rates
References in laws to the rates of pay for GS–16, 17, or 18, or to maximum rates of pay under the General Schedule, to be considered references to rates payable under specified sections of Title 5, Government Organization and Employees, see section 529 [title I, § 101(c)(1)] of Pub. L. 101–509, set out in a note under section 5376 of Title 5.
National Commission on New Technological Uses of Copyrighted Works
Pub. L. 93–573, title II, §§ 201–208,Dec. 31, 1974, 88 Stat. 1873–1875, as amended by Pub. L. 94–314, June 21, 1976, 90 Stat. 692; Pub. L. 95–146, Oct. 28, 1977, 91 Stat. 1226, created in the Library of Congress a National Commission on New Technological Uses of Copyrighted Works to study and compile data on (1) the reproduction and use of copyrighted works of authorship (A) in conjunction with automatic systems capable of storing, processing, retrieving, and transferring information, and (B) by various forms of machine reproduction, not including reproduction by or at the request of instructors for use in face-to-face teaching activities, and (2) the creation of new works by the application or intervention of such automatic systems or machine reproduction, required the Commission to submit a final report to the President and Congress on or before July 31, 1978, and provided that the Commission terminated the sixtieth day after submitting the final report.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


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What's So Hot About...
3D TV – Coming to a Home Near You!
From the lush forests of Pandora in Avatar to Woody and Buzz's hair-raising adventures in Toy Story 3 to the epically comic battle to save Metro City in Megamind, 3D has become the technology of choice for film makers and movie lovers around the world. This love for 3D technology on the silver screen has stirred a rising demand for the 3D experience at home – for movies, TV shows and live sports, too.
Cox at the Forefront of 3D Broadcasting
To satisfy this demand and complement ongoing advancements in digital technology, Cox has broadcast several live 3D sport events recently, including the 2010 Masters Tournament, the PGA Championship and a Ducks-California Golden Bears college football game. To stay on the forefront of this exciting technology, we are partnering with networks to provide more 3D sports, movies and entertainment through the year.
The Basics of Enjoying the Home 3D Experience
3D TVs rolled out for sale in March 2010 and the demand has grown exponentially since. But bringing the 3D experience to your home is more than just buying a new TV, getting the special glasses and switching it on. Before you bring the 3D experience into your home, carefully consider the following:
- Your 3D TV
Your first important step for experiencing 3D TV, you will need an HDTV with 3D functionality that was manufactured after January 2010. These new models allow you to watch regular TV as you always do, but they will shift into 3D mode when 3D programming is detected. As for price, the current retail pricing for 3D-capable TVs range from $2,400 to $3,000.
- 3D TV cable set up
Make sure that your Cox HD or HD DVR receiver, or the receiver from your current cable provider, has an HDMI output connection and that the receiver is connected to your 3D TV's HDMI input via an HDMI cable.
- 3D glasses
To get the full 3D experience, you will need a pair of special glasses. Many 3D TVs come with at least one pair, but for family and guests, you're going to have to buy more separately. On average, the price for one pair is $150.
- Availability of 3D Content on TV
Right now, there are few 3D programs on TV, but more are being offered every day. As mentioned above, Cox recently broadcast several live 3D sports events in 2010. Our plan is to offer more 3D sports as well as 3D movies, TV shows and live entertainment throughout the year.
- Watching pre-recorded 3D movies
To watch the latest recorded 3D movies on your 3D set, you'll need to buy a late-model 3D Blu-ray player. The price for one of these is about $400.
Cox is excited about providing this latest achievement in TV viewing to our customers. For more information on our 3D service, click here.
Maximize your at-home viewing experience with a home theater.
Get ready for a lesson in what's so hot about sports with Cox... and a healthy dose of smack talk.
Forget the movie theater! Experience 3D at home with Cox Advanced TV.
People love Facebook or they hate Facebook. Whatevs, as the kids say.
Get pointers on how to best use your clicker.
Learn how to get the most from your TV service with the pros at Cox.
The pros at Cox give their tips on setting up your home network.
Maximize your at-home viewing experience with a home theater.
Learn how to get the most from the Web with the pros at Cox Communications.
Setting up parental controls is easy with Cox.
Worried about online safety? Learn about security from the Cox pros.
Let your Cox services help keep your family bond strong, even if you're not all under the same roof.
Find out how this family stays connected across the country.
Find out how this family uses Cox services to stay ahead of the curve.
Bring it all together to stay in touch with the world.
If music is your life, Cox services can help you live it.
How can you keep your kids safe with so much out there?
Get ready for a lesson in what's so hot about sports with Cox... and a healthy dose of smack talk.


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Chemical Week Magazine :: Regulatory
Cefic: Europe needs competitive energy and an affordable climate policy
February 20, 2014 | Michael Ravenscroft
Cefic has called for competitive energy and an affordable climate policy, on the eve of a European Council meeting on competitiveness. Gas and electricity costs in the United States are one third and half, respectively, of those in the European Union, according to Cefic. "If the EU wants to raise industry's contribution to EU GDP to as much as 20% by 2020, industry should not be saddled with additional policy costs," Cefic says. "The commissions greenhouse gas (GHG) emission reduction proposals would mean a 70% reduction from 1990 levels for...
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Quick View
CastelrossoThis tri-layered Italian wonder is a cross between a smooth, creamy-driven French tomme and a firm, curdy English cheddar. Read More
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Bellwether Farms
San AndreasThis nicely balanced raw farmstead sheep tomme is made in California, near the fault line for which it is named. Nutty with subtle hints of buttercups and moss. Read More
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Toma WalserNEW ARRIVAL! The Walsers were a Germanic people that wound up settling throughout the Alps, including the Piedmont region of northern Italy. This sweet smelling, ivory-colored gem is named for them. Read More


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Bortezomib in Treating Patients With Stage IIIB or Stage IV Lung Cancer
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
This phase II trial is studying how well bortezomib works in treating patients with stage IIIB or stage IV lung cancer. Bortezomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Adenocarcinoma of the Lung
Bronchoalveolar Cell Lung Cancer
Non-small Cell Lung Cancer
Recurrent Non-small Cell Lung Cancer
Stage IIIB Non-small Cell Lung Cancer
Stage IV Non-small Cell Lung Cancer
Drug: bortezomib
Phase 2
|Study Type:
|Study Design:
|Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|Phase II Study of Bortezomib (PS-341) for Patients With Advanced Bronchiolo-Alveolar Carcinoma (BAC) or Adenocarcinoma With BAC Features
- Objective Response Rate With Bortezomib Evaluated by Both RECIST Criteria and Computer-assisted Image Analysis. [ Time Frame: Up to 5 years ] [ Designated as safety issue: No ]A response rate of 20% or more with bortezomib would be of interest for further evaluation, whereas a response rate of less than 5% would be of no interest. Response defined as a confirmed CR or PR.
- Progression-free Survival [ Time Frame: Up to 5 years ] [ Designated as safety issue: No ]Progression Free Survival using the product-limit method of Kaplan and Meier
- Overall Survival [ Time Frame: Up to 5 years ] [ Designated as safety issue: No ]Overall Suvival using the product-limit method of Kaplan and Meier.
|Study Start Date:
|June 2005
|Study Completion Date:
|December 2010
|Primary Completion Date:
|December 2010 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Arm I
Patients receive bortezomib IV over 3-5 seconds on days 1 and 8.
Drug: bortezomib
Given IV
Detailed Description:
I. Determine the objective response rate in patients with stage IIIB or IV bronchoalveolar carcinoma (BAC) or adencarcinoma of the lung with BAC features treated with bortezomib.
I. Determine the progression-free and overall survival of patients treated with this drug.
II. Determine the time to disease progression in patients treated with this drug.
III. Determine predictors of response, based on molecular correlative studies of tumor and blood, in patients with treated with this drug.
OUTLINE: This is a multicenter study. Patients are stratified according to prior epidermal growth factor receptor inhibitor therapy (yes vs no).
Patients receive bortezomib IV over 3-5 seconds on days 1 and 8. Courses repeat every 21 days in the absence of disease progression or unacceptable toxicity.
After completion of study treatment, patients are followed for survival.
|Ages Eligible for Study:
|18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Histologically confirmed bronchoalveolar carcinoma (BAC) or adenocarcinoma of the lung with BAC features:
- Stage IIIB or IV disease:
- Patients with stage IIIB disease must be ineligible for definitive combined modality treatment with radiotherapy and chemotherapy
Measurable disease, defined as >= 1 unidimensionally measurable lesion >= 20 mm by conventional techniques or >= 10 mm by spiral CT scan:
- Previously irradiated lesions are considered measurable only if lesion progressed after completion of radiotherapy
No unstable brain metastases:
- Brain metastases that are stable for ≥ 1 month after completion of prior radiotherapy, stereotactic surgery, or surgery are allowed
Performance status:
- Life expectancy >3 months
- Bilirubin normal
- AST and ALT =< 2.5 times upper limit of normal
- Creatinine normal OR creatinine clearance >= 60 mL/min
- No symptomatic congestive heart failure
- No unstable angina pectoris
- No cardiac arrhythmias
No more than 1 prior chemotherapy regimen for advanced BAC:
- Prior gefitinib or other known epidermal growth factor receptor (EGFR) inhibitors are not considered a systemic chemotherapy regimen
- At least 3 weeks since prior chemotherapy (6 weeks for nitrosoureas or mitomycin)
- At least 4 weeks since prior corticosteroids
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must use effective contraception before, during, and for 30 days after completion of study treatment
- No ongoing or active infection
- No other malignancy within the past 3 years except adequately treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix, or adequately treated stage I or II cancer that is in complete remission
- No peripheral neuropathy >= grade 2
- No known hypersensitivity to bortezomib, boron, or mannitol
- No psychiatric illness or social situation that would preclude study compliance
- No other uncontrolled illness
- No concurrent routine granulocyte colony-stimulating factors (e.g., filgrastim [G-CSF] or sargramostim [GM-CSF])
- At least 2 weeks since prior radiotherapy
- Recovered from prior therapy (alopecia allowed)
- At least 2 weeks since prior EGFR inhibitors
- At least 4 weeks since prior anticonvulsants
- No prior bortezomib
- No concurrent antiretroviral therapy for HIV-positive patients
- No other concurrent investigational agents
- No other concurrent anticancer therapy
- Concurrent bisphosphonates for bone metastases allowed
- Absolute neutrophil count >= 1,500/mm3
- Platelet count >= 100,000/mm3
Please refer to this study by its ClinicalTrials.gov identifier: NCT00118144
|United States, California
|City of Hope
|Duarte, California, United States, 91010
|Principal Investigator:
|David Gandara
|Beckman Research Institute
No publications provided
|Responsible Party:
|National Cancer Institute (NCI)
|ClinicalTrials.gov Identifier:
|NCT00118144 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 8, 2005
|Results First Received:
|August 4, 2014
|Last Updated:
|August 4, 2014
|Health Authority:
|United States: Food and Drug Administration
Additional relevant MeSH terms:
Adenocarcinoma, Bronchiolo-Alveolar
Carcinoma, Non-Small-Cell Lung
Lung Neoplasms
Bronchial Neoplasms
Carcinoma, Bronchogenic
Lung Diseases
Neoplasms by Histologic Type
Neoplasms by Site
Neoplasms, Glandular and Epithelial
Respiratory Tract Diseases
Respiratory Tract Neoplasms
Thoracic Neoplasms
Antineoplastic Agents
Pharmacologic Actions
Therapeutic Uses
ClinicalTrials.gov processed this record on October 09, 2015


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KARINA Bobbies Collection Dot
We know you want the goods as soon as possible, which is why orders received by 3pm ET leave our warehouse the very same day. We'll send you an email that day to confirm shipment and the email will include your tracking information.
Our warehouse is closed Saturday & Sunday, so orders received after 3pm ET on Fridays will not ship out until Monday.
Based on 1 Review
MandiDallasHairBlondeDry HairColor Treated HairFine or Thin HairThick or Coarse HairCute & Colorful Bobbies -- Just For FunI bought these brightly colored (2 ½ inch long) bobby pins to pull up the long layers of my thick, long blonde hair & add a little pop of color. These do not slip but since I have very thick hair, I need two to hold my hair back in a half up/half down undo. These hold well but they don't appear to be any better made or markedly different than the other brands I've owned & in time, I imagine they'll become less taut & reliable as they become stretched.
As a blonde, the blue is looks the prettiest against my light blonde hair but I am disappointed that the pink was a touch too bright (but it would look quite lovely worn in darker hair). While the dotted black & white is sweet, the white is the flat & a tad uninspiring. I will use this every so often but wanted a little more 'oomph'.9 out of 10 shoppers thought this review was helpful.
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There's one thing on my mind from quite some time. I often see people rocket jumping through the map, going around in seconds, never hitting a wall or a corner. It feels they are following a path on auto, if you know what i mean.
I try really hard to calculate where my next rocket should go so I can continue going forward with high speed (tunnels, doors etc.) but somehow I always hit a corner or something and bam, stop.
Do you have any tips how I can improve that? Any videos with voiceover? Anything to read? Anything that will help me improve moving through the map, full speed rocket jumping?
Best wishes,
i'm talking about this kind of behavior


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Business Facilities Location Spotlights will educate you about a location's target industries, quality of life, latest news, statistics, and available incentives.
Ak-Chin Indian Community – The Ak-Chin Indian Community has launched its Business Facilities Location Spotlight. The Ak-Chin Indian Community offers low lease rates, substantial tax savings and other economic advantages at its Santa Cruz Commerce Center. With access to a skilled workforce, affordable housing and major transportation corridors, our native environment provides an unparalleled business climate to grow business while reducing costs.
Click here to visit the Ak-Chin Indian Community Location Spotlight.
Buckeye Power – Buckeye Power has unveiled its new Business Facilities Location Spotlight. Buckeye Power provides comprehensive economic development services to 77 of Ohio's 88 counties. This site contains current information to help you make an informed business expansion or relocation decision.
Click here to visit the Buckeye Power Location Spotlight.
City of Brampton – City of Brampton has unveiled its new Business Facilities Location Spotlight. With a population approaching 600,000 Brampton is the 9th largest city in Canada and the 3rd largest in the Greater Toronto Area (GTA). This young, educated, and multicultural workforce of over 190,000 strong and continues to grow at an annual rate of 4.2 per cent or 18,000 new residents per year, making Brampton the 2nd fastest growing city in Canada. Come to Brampton and see what a people-powered economy can do for you.
Click here to visit the City of Brampton Location Spotlight.
Greater Fort Lauderdale/Broward County – Greater Fort Lauderdale Alliance has unveiled its new Business Facilities Location Spotlight. As the primary economic development organization for Greater Fort Lauderdale/Broward County, the Greater Fort Lauderdale Alliance focuses on creating, attracting, expanding and retaining high-wage jobs and capital investment in high value targeted industries, developing more vibrant communities, and improving the quality of life for our area's citizens.
Click here to visit the Greater Fort Lauderdale Alliance Location Spotlight.
Hoosier Energy – Hoosier Energy has unveiled its new Business Facilities Location Spotlight. The Hoosier Energy Power Network's Economic Development team is dedicated to providing valuable site selection information and assistance to companies considering a relocation or expansion in Indiana or Illinois.
Click here to visit the Hoosier Energy Location Spotlight.
Joplin Regional Partnership – Joplin Regional Partnership has launched its new Business Facilities Location Spotlight. The Joplin Region is comprised of Southwest Missouri and Southeast Kansas, where you'll find five counties working in partnership to make your business expansion or location successful and profitable.
Click here to visit the Joplin Regional Partnership Location Spotlight.
Lubbock, Texas – Lubbock, Texas and the Lubbock Economic Development Alliance (LEDA) have unveiled a new Business Facilities Location Spotlight. Lubbock's highly skilled and educated workforce, proximity and connection to major national and international markets, and affordable utility and living costs make it the ideal place to grow a business. Known as the "Hub City" of West Texas, Lubbock's diverse economy is based on manufacturing, agriculture, wholesale and retail trade services, as well as government, education and health care.
Click here to visit the Lubbock, Texas Location Spotlight.
River Bend Center, CT – River Bend Center has launched its new Business Facilities Location Spotlight. River Bend has 40 years of experience and success developing high-tech business campuses in Connecticut, Massachusetts, New Jersey, Ohio, Pennsylvania, California, Canada and United Kingdom. River Bend Center has a proven record of reliability and connectivity, featuring backup generators with uninterruptible power supplies, emergency maintenance response, and carrier neutral access to 10 different fiber-optic providers.
Click here to visit the River Bend Center Location Spotlight.
Topeka, Kansas – Topeka, Kansas has launched its new Business Facilities Location Spotlight. Topeka has the ability to offer valuable incentives to incoming companies with the most aggressive, flexible local incentive package in the Midwest.
Click here to visit the Topeka, Kansas Location Spotlight.
Wheeling, Illinois – Wheeling, Illinois has launched its new Business Facilities Location Spotlight. Located in the heart of Chicago's prestigious northern suburbs, Wheeling is a diverse and dynamic community of 40,000 people, distinguished by its unique balance of industry, commercial development, and residential neighborhoods.
Click here to visit the Wheeling, Illinois Location Spotlight.


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What is a Power of Attorney?
A Power of Attorney is a written document that authorizes another person to perform some lawful act that you could do if you were personally present at the time. The Power of Attorney can only be recognized and accepted by others while you are still alive. And, unless you make the power durable, it will not be recognized or accepted by others when you are incapacitated by coma or mental defect. Some examples of what a Power of Attorney can be used for are as follows: transfer of a car title; transfer of title to land; opening or closing bank accounts; entering into contracts or other business affairs; settling claims for or against you; providing care and maintenance for your family.
The Power of Attorney protects the person who agrees to let someone else transact business for you. Therefore, if the person does not feel adequately protected by the Power of Attorney, they do not have to accept the authority of the person trying to take action on for you. As an example, a judge would not accept a relinquishment of your parental rights signed by someone producing a General Power of Attorney.
There are basically two kinds of Power of Attorney. A General Power and a Special Power. A Special Power of Attorney is preferred because it specifically identifies and limits the authority of the person trying to act on for you. Texas has adopted a Statutory Durable Power of Attorney that allows you to select general or special powers.
A Power of Attorney generally becomes effective on the day you sign it. It will remain in effect until the date of expiration written within the document or upon your death or disability. If you desire to terminate a Power of Attorney that you have given to another person, you must specifically revoke that power. If the original Power of Attorney was recorded in county records then the revocation must also be recorded in county records. You must also deliver a copy of the revocation to the person having your Power of Attorney and provide notice of the revocation to any person who might be expected to conduct business with the person on your behalf.


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Welcome to LUNG FORCE Walk - Columbus
We are a force to be reckoned with. Only A Force of Many Can Stand Up To:
- the frightening rise of lung cancer in women
- the deadly disease that is COPD
- the daily challenges that asthma sufferers face
- pollution that threatens our lungs and our lives
With your participation and help, our LUNG FORCE Walk will make a difference in lives that desperately need it. Register today, because now is the time to raise our voices against lung cancer—and for lung health.
Join us for the LUNG FORCE Walk Columbus on the morning of Saturday, June 6, 2015 at 9:00am. The morning will include a 2.5 mile walk, fitness elements, lung health information, kids' activities, music and MORE! At every LUNG FORCE Walk, we harness our collective power to make a difference for the people we love, and raise our voices for everyone who is touched by lung disease.
Address to Easton Town Center:
160 Easton Town Center, Columbus, OH 43219


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Rising energy prices in Germany are forcing the pharmaceutical and chemical conglomerate Bayer to threaten a move to China. The culprit is Germany's nuclear energy exit bill, passed last month in reaction to Japan's Fukushima nuclear power plant disaster. The bill orders a nuclear phase-out by 2022. Meanwhile, China plans to build 36 new nuclear power plants during the next decade. Germany's Deutsche Welle reports Bayer CEO Marijn Dekkers predicted, "Energy prices will continue to rise, and they are already the highest in the EU." He said in the face of rising prices, "a global business such as Bayer would have to consider relocating its production to countries with lower energy costs." The move would leave 35,000 workers in Germany unemployed.
Countries Bayer is considering include China, Brazil, and India, where the company has already begun significant expansion. According to the World Nuclear Association (WNA), Brazil plans to bring four new large reactors online by 2025, significantly expanding the current 3 percent of its electricity generated by two existing nuclear reactors.
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Extensive meaning details?In my case, the founder partner of my law firm wrote a recommendation for me and sent them directly to the Deans. His letter is kinda general though, since he only knew me briefly and from other partners.I don't know whether that may help or hurt.
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You are here Home Travel tools At the airport Airport check-in times
US Airways closes passenger and baggage check-in 30 minutes prior to departure for domestic travel and 60 minutes prior to departure for international travel. Always get to the airport with plenty of time to check in, get your boarding pass, clear security and get to the gate.
If you're leaving from one of these airports, you must check in at least 45 minutes before departure:
You must check in 20 minutes prior to your scheduled departure (no bags) and 30 minutes prior if you need to check bags.
You must check in 75 minutes prior to your scheduled departure, whether you're checking bags or not.