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Is it a bird? Is it a plane? No… it's the iPad! Will.i.am turned renegade crime fighter after his Bentley was burgled last week in the Hollywood Hills. The villains made off with over $10,000 of the Pea's property including jewelry and his swanky new iPad. Bad move, because the Black Eyed Pea went hi-tech and used the gadget's in-built tracking system to find the bad guys and forwarded the co-ordinates to the cops. The thieves are currently on the run but thanks to Will's – well, the iPad's – crime busting prowess, the cops are right behind them. Great job on using your superpowers for good, and not for evil – aka (alleged) Perez Hilton beat-downs.
One questions though, what the hell was he doing rolling with that much cash and jewelry anyway?
[Photo: Getty Images]


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Posted: August 21, 2014
U.K. rockers Young Guns have dropped a new music video for the upbeat and anthemic "I Want Out," which is the lead single off their upcoming album expected in early 2015.
The song shot straight to No.1 on the iTunes Rock chart on the day of release and remains at the top of the iTunes Viral 50.
The clip below features the band performing in front of various psychedelic, rapidly changing backdrops. What's more, both guitarists just happen to be rocking Gretsch guitars — the G6139CB Falcon™ Center-Block Single Cutaway and the 6139T-CBDC Falcon™ Center-Block Double Cutaway.
Tags: 6139T-CBDC Falcon™ Center-Block Double Cutaway, G6139CB Falcon™ Center-Block Single Cutaway, I Want Out, video, Young Guns
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BROOKSTON (AP) — Indiana State Police say troopers are investigating a pickup truck being shot while driving on Interstate 65 near Lafayette.
Police say three people were inside the truck when it was hit Sunday evening while northbound approaching the Indiana 18 interchange about 15 miles north of Lafayette.
No one was injured.
Police say the bullet went through the passenger-side door window and out the rear window behind the driver.
State police asked that anyone who knows of target shooting or other activity in the rural area to report it to troopers. Police say that the shooting could have caused an accident on the interstate and resulted in injuries and possible deaths.


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Environmental Law Society
The Environmental Law Society promotes an awareness of present and future issues in the field of environmental law. It sponsors programs featuring guest speakers on topics of interest to its members and the community.
Student Leaders
- President: Kelly McBride
- Vice President: Laren VanHook
- Treasurer: Tyler Woolard
- Secretary: Alonzo Provencio


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science that examines more broadly the role of science and scientists in a variety of decision and policy processes (e.g., Brunner and Ascher, 1992; Gunderson, Holling, and Light, 1995; Sarewitz, Pielke, and Byerly, 2000; van Asselt, 2000; Freudenburg and Gramling, 2002; Ascher, 2004). Although this tradition contains useful insights regarding how science is used and misused in policy processes, we did not find it useful for judging which research areas are most likely to produce knowledge that will be used.
The National Academies of Sciences, Engineering, and Medicine
500 Fifth St. N.W. | Washington, D.C. 20001
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"1 Introduction."
Decision Making for the Environment: Social and Behavioral Science Research Priorities.
Washington, DC: The National Academies Press, 2005.
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continued On Thursday, 22 trails were open with four lifts, including the Northwoods Gondola and three chairs closer to the summit: the Topridge Triple, High Peaks Chair and Straight Brook Quad.
Terrain was open for upper-level intermediates and experts only, and some walking was required on the open trails.
Gore Mountain opened the ski season the day after Thanksgiving, but it was rough going after that, with warm temperatures and a lack of snowfall throughout the winter.
"This is my 13th winter at Gore, and this is weather I've never experienced before," Stanton said. "I've talked to a lot of people who've been around a lot longer than me and they say the same. It's been frustrating for us, but at the same time we've been encouraged by all the great words our skiers and riders have told us."
The ski industry throughout the East took a big hit this year. Talking with her competitors and partners in the business, Stanton said many ski centers saw up to a 30 percent drop in business. Luckily, Gore is only 15 percent off its average season.
"This year we were fortunate to have installed 160 new tower guns before opening the '11-12 winter season, and if there's one year that could have been better timed, I can't imagined what it is," Stanton said. "So I know we were able to overcome a lot of challenges with that snowmaking improvement and with our ideal location next to the Hudson River."
After a March 1 snowstorm dumped more than a foot of snow in North Creek, Gore had 100 percent of its trails open for the first and only time this season, for two days. That included the Hudson Chair connection to the North Creek Ski Bowl, a ski center owned by the town of Johnsburg.
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Team pride can be shown on all kinds of different apparel, but there's something special about showing your dedication to your favorite team with a jersey. Your young fan can display their Mets team spirit with pride when they show off this mesh pullover v-neck jersey from Stitches at the next big game. It features a tackle twill team wordmark logo across the front and raglan sleeves for a stylish look that everyone is sure to notice! Now that's how you rep the Mets!
- 100% Polyester fabric
- Contrast striping on collar and cuffs
- Imported
- Officially licensed Mets jersey
- Quality embroidery
- Rib-knit collar & cuffs
- Tight weave mesh
Special event items are produced by manufacturers only after the outcome of a game or event. These are advanced sale items and will ship immediately after they are received in our warehouse.
Manufacturer direct items are shipped directly from the manufacturer. These items are not available for international or expedited shipping.
Customized items can be personalized with options such as your name, your favorite number, and/or designs. Some options may be limited by league rules.


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Yay! Can't wait to try it!
Steam Marines is a Squad-Based Tactical Roguelike being developed by Worthless Bums. It features: - 2D retro-styled art and turn based action. - Procedurally Generated Levels. - A squad of combatants fighting for their lives in monster filled levels. - Use your squad to cover defensive positions or funnel enemies into chokepoints to blow them up. Steampunk spaceship under attack by aliens, you say? The aim of the game is to progress through the various decks of your besieged steampunk spaceship in order to repel the alien invaders and get out of dodge. It features permadeath and will have a recruitment system. Build your squad members into deadly, long-range marksmen, or up-close-and-personal death machines. But no one is invincible, and if someone dies you'll have to replace him/her with a raw recruit. If the entire squad dies it's game over.
Steam Marines v0.5.8a has arrived with new sounds, directional sprites, and other goodies!
Posted by Worthless_Bums on Aug 13th, 2012
Hello, everyone!
Everything is looking great. For v0.5.8a we've got new sounds from Tapio Liukkonen, directional sprites for Detocroix, and gameplay tweaks and changes to alleviate the difficulty concerns of players. There's also some really awesome steampunk music you'll all get to hear on August 30th!
Also a very special thanks to two people - Robert Shenton for making this Steam Marines logo out of the kindness of his heart:
And to Delyth Angharad for taking the time to make a YouTube video of the v0.5.7 alpha build!
I'm sure you'll be seeing their names again! And as usual you can download the latest build of Steam Marines on the official website or on the forums. Thanks for reading!
Yay! Can't wait to try it!
Nice, Looks Good
This, is an excellent update. This compared to 0.5.7, although not much seems to change, the balance is far better. I feel like I'm actually playing the game right now. Things i noticed:
+ There's a some bugs when 1 or more members of your team die. Things like when you enter another deck, your dead comrades are there, with 0 health and actions though, but they still move on Solo-mode, and still block up things
+ I can't really tell at this stage, but do the enemies get tougher with each deck descended? If not, they should :)
+ I'm not sure if you did this on purpose, but on follow-mode, your whole team changes to the colour of the solo-er. If this is intended, i wouldn't reccomend it, you need to be consistent with that kind of thing.
+ Grenades don't seem to do much?
Anyway, great job, looking forward to more!
Hey BaronVengeous,
- I've had reports of the death/deck bug and I'm looking into it.
- The enemies currently do not get tougher and there are only three in-game atm. There were more varied/difficult monsters prior to the steampunk change and I'm waiting on art assets.
- Thanks for reporting the follow mode bug; I didn't know that!
- Grenades should deal aoe damage up to two tiles away. Currently they only trigger if the grenade actually hits a valid target (you can't throw it between two targets yet).
Thank you for the excellent feedback!


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The Annual British Studies Shakespeare Talk and 2011 Cranfill Shakespeare Lecture
Fri, September 23, 2011 • 3:00 PM • Prothro Theatre, Harry Ransom Center
What's for Dinner on a Desert Island: Feast and Famine in The Tempest. Lecture by Professor Leonard Barkan, Princeton University
If one dips below the surface of The Tempest, even slightly, one discovers that the question of food and drink is intriguingly pervasive. No surprise, since the early modern literature about unknown worlds beyond Europe was often obsessed with the question of what (or who) was eaten in those far-off places. Caliban's menu, Stephano's wine cask, the sumptuous banquet that magically appears and disappears in front of the hungry travellers: these add up to a significant dimension of the play.
Leonard Barkan is the Class of 1943 University Professor and Chair of the Department of Comparative Literature at Princeton University where he has taught courses on subjects including Shakespeare, Michelangelo, Narcissus, Word and Image, and Comedy. He is the author of more than a half-dozen books; the most recent, Michelangelo: A Life on Paper, was published in November 2010. He is also a regular contributor to publications in both the U.S. and Italy, where he writes on the subject of food and wine. A recipient of the Morton Dauwen Zabel Award from the American Academy of Arts and Letters, he has been a professor of English and of Art History at universities including Northwestern, Michigan, and N.Y.U.
This event is co-sponsored by the Department of Art & Art History, the Program in British Studies and the Center for European Studies


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Novel particle reagents for light scattering immunoassays are provided. The particle reagents are high refractive index shell-core polymers covalently bonded to compounds of biological interest or analogs thereof. A method of measuring unknown concentrations of these compounds of biological interest by measuring changes in turbidity caused by particle agglutination or its inhibition is also provided.
1. A method for measuring compounds of biological interest comprising the steps of
(A) incubating
(1) a particle reagent having high refractive index consisting essentially of:
(a) a polymer particle having an inner core and an outer shell wherein the inner core is a polymer having a refractive index of not less than 1.54 as measured at the wavelength of the sodium D line and wherein the outer shell is a polymer of
(i) an ethylenically unsaturated monomer having a functional group capable of reacting with a compound of biological interest selected from the group consisting of epoxy, carboxyl, amino, hydroxyl and aldehyde,
(ii) optionally, other ethylenically unsaturated monomers in an amount sufficient to produce water insoluble polymer particles, and
(iii) not more than 10 parts by weight of the outer shell of the monomers of the inner core, said outer shell being formed by polymerization in the presence of said inner core and wherein said polymer particles has approximate diameter range of 0.03-0.1 μm;
and is covalently attached to
(b) an analog of a compound of biological interest;
(2) a liquid suspected of containing the compound of biological interest; and
(3) an agglutinating agent; and
(B) photometrically measuring increased particle size resulting from agglutination.
2. The method of claim 1 wherein during the incubation step (A) there is also present an agglutinating accelerator.
3. The method of claim 2 wherein the agglutinating accelerator is selected from the group consisting of polyethylene glycol and sodium dodecyl sulfate.
This application is a Continuation-in-Part of U.S. patent application Ser. No. 315,922, filed Oct. 28, 1981, now U.S. Pat. No. 4,401,765, issued Aug. 30, 1983, which is a Continuation-in-Part of U.S. patent application Ser. No. 298,473, filed Sept. 1, 1981, now abandoned.
This invention relates to novel particle reagents consisting of shell-core particles in which the high refractive index of the core results in high sensitivity to light scattering measurements and the shell contains functional groups to which compounds of biological interest can be covalently bonded. In particular, the compounds of biological interest are antibodies, antigens, and antigen analogs and the particle reagents are designed for use in light scattering immunoassay.
The agglutination reaction has long been used in visual (semiquantitative) and quantitative assays for a wide variety of bacteria, cell-surface antigens, serum proteins or other analytes of clinical interest. Agglutination results from the reaction of bivalent antibodies with multivalent antigens of interest to produce aggregates which can be detected and/or measured in various ways. Similarly, the same reaction can be utilized for the detection of specific antibodies by the agglutination reaction caused by the addition of the corresponding antigen.
In order to produce large, crosslinked aggregates the number of reactive sites on the antigens must be at least 2. Therefore, when the detection of monovalent haptens was desired, the reaction scheme was modified as follows: A multivalent form of the antigen such as a hapten-protein conjugate was prepared and the hapten present in a sample could compete with its multivalent form for the available binding sites of the antibody thereby reducing the amount of agglutination. This technique is referred to as inhibition of agglutination.
Production of multivalent forms of haptens is old in the art. Frequently the hapten is bonded to a carrier protein as is done in the preparation of immunogens. The stoichiometry of the reaction can be adjusted to place three or more haptens per protein molecule, the exact number being determined by the needs of the particular assay in which the material will be utilized.
Increased sensitivity to visual or instrumental detection of agglutination or its inhibition can be achieved by the use of particle reagents as carriers, rather than soluble proteins or protein conjugates. It has been shown, for example, that antiserum to hen ovalbumin was 2000-fold more sensitive in precipitating hen ovalbumin coated on colloidion particles than in precipitating hen albumin itself; H. N. Eisen, "Immunology", Harper and Row, 1974, page 394.
Antibody particle reagents are also known. A common method for preparation of such reagents is by adsorption of the antibodies onto the surface of suitable adsorbents. Polystyrene-based latex particles have been used extensively for this purpose. For example, U.S. Pat. No. 3,912,805, issued Oct. 14, 1975 to Cayzer, et al., describes an immunological diagnostic reagent wherein antibodies raised to fibrinogen degradation products are adsorbed to latex particles. These reagents, however, are susceptible to desorption during storage or use leading to variations in reagent properties. This, in turn, can adversely affect assay sensitivity and reproducibility.
To overcome the problems of desorption, particle reagents can be prepared by covalent attachment of the compounds of biological interest to the surface of particles. Polystyrene polymers have been modified to include functional groups capable of covalent protein attachment. U.S. Pat. No. 4,064,080, issued Dec. 20, 1977, discloses styrene polymers with terminal aminophenyl groups and proteins attached to them. U.S. Pat. No. 4,181,636, issued Jan. 1, 1980, discloses carboxylated latex polymers coupled to immunologically active materials through a water soluble activating agent and their use as diagnostic reagents in agglutination tests. U.S. Pat. No. 4,210,723, issued July 1, 1980, describes shell-core latex polymer particles of 0.15-1.5 μm diameter having free epoxy groups on the surface of the particles and the coupling of proteins through these epoxy groups.
Other polymeric systems have also been developed for later attachment of immunologically active materials. U.S. Pat. No. 4,264,766, issued Apr. 28, 1981, discloses latex polymers, having a particle size of 0.01-0.9 μm and having active groups such as carboxyl and amino groups to which water soluble polyhydroxy compounds can be attached covalently. Through the utilization of activating agents such as carbodiimides, immunologically active materials were attached to the latex particle/polyhydroxy compound carriers to form diagnostically useful reagents.
There is a need for a stable particle reagent which possesses high sensitivity for use in light-scattering agglutination assays and which can be prepared conveniently by the covalent attachment of compounds of biological interest to a particulate carrier.
The particle reagent of this invention has a high refractive index and consists essentially of:
(A) a polymer particle having an inner core and an outer shell wherein the inner core is a polymer having a refractive index of not less than 1.54 as measured at the wavelength of the sodium D line and wherein the outer shell is a polymer of
(1) an ethylenically unsaturated monomer having a functional group capable of reacting with a compound of biological interest selected from the group consisting of epoxy, carboxyl, amino, hydroxyl and aldehyde,
(2) optionally, other ethylenically unsaturated monomers in an amount sufficient to produce water insoluble polymer particles, and
(3) not more than 10 parts by weight of the outer shell of the monomers of the inner core, said outer shell being formed by polymerization in the presence of said inner core; and wherein said polymer particle has an approximate diameter range of 0.03-0.1 μm and is covalently attached to
(B) a compound of biological interest, its antigen or an analog thereof or its antibody.
The compound of biological interest can be attached to the polymer particle directly or through a proteinaceous material.
A method of this invention for measuring compounds of biological interest comprises the steps of:
(A) incubating
(1) a particle reagent having high refractive index consisting essentially of:
(a) a polymer particle having an inner core and an outer shell wherein the inner core is a polymer having a refractive index of not less than 1.54 as measured at the wavelength of the sodium D line and wherein the outer shell is a polymer of
(i) an ethylenically unsaturated monomer having a functional group capable of reacting with a compound of biological interest selected from the group consisting of epoxy, carboxyl, amino, hydroxyl and aldehyde,
(ii) optionally, other ethylenically unsaturated monomers in an amount sufficient to produce water insoluble polymer particles, and
(iii) not more than 10 parts by weight of the outer shell of the monomers of the inner core, said outer shell being formed by polymerization in the presence of said inner core and wherein said polymer particles has an approximate diameter range of 0.03-0.1 μm and is covalently attached to
(b) the compound of biological interest or an analog thereof or its antibody;
(2) a liquid suspected of containing the compound of biological interest; and
(3) an agglutinating agent; and
(B) photometrically measuring increased particle size resulting from agglutination.
The method of this invention for measuring proteins can be carried out directly without an agglutinating agent with the appropriate complementary particle reagents.
This invention relates to novel particle reagents with optimal properties for use in sensitive light scattering immunoassays. The particle reagents are designed to maximize the sensitivity of the immunoassays by (1) being formed of a core material of high refractive index; (2) possessing a shell material which is capable of covalently binding to compounds of biological interest or analogs thereof; and (3) being of a small particle size for optimal sensitivity in the immunoassays.
By antigen analog or analog of the compound of biological interest is meant any substance or group of substances which share antigenic determinants and, therefore, behaves substantially the same as the compound of biological interest with respect to binding specificity for the antibody to the compound of biological interest.
The light scattering properties of particle suspensions depend on several variables, most importantly the particle size, the refractive indices of the core and the suspension medium, and the wavelength of light used for measurement. Thus, the selection of core material, particle size, and wavelength of detection of the agglutination reaction are all important factors in optimizing assay sensitivity. These factors can be determined by the type of light scattering detection means used.
During visual observation of the agglutination reaction, a broad band of wavelengths, between approximately 400 and 650 nm, is being utilized. Since the light scattering response varies over this wavelength range, the visual observation results in an averaging of the effects of many wavelengths which is less sensitive than choosing the optimum wavelength for a given particle size and refractive index. For particles which are small compared to the wavelength of light, the scattering increases with the inverse 4th power of the wavelength and the magnitude is dependent upon the refractive index. When the wavelength of light approaches an absorption band of the particle, there is an increase of refractive index and thus the light scattering properties are sensitive also to the optical dispersion of the scattering element and the wavelength functionality may exceed the 4th power.
For the turbidimetric detection of particle size change at a given wavelength of measurement it is imperative that the particle size and refractive index be chosen with care since the turbidimetric signal goes through a maximum, producing a double-valued response with little or no sensitivity at the peak. In addition, the slope sensitivity is greater on the small particle size side of the peak than on the large and it increases with increasing refractive index ratio of particle to medium.
For these reasons, small particles of high refractive index with short wavelength detection are preferred for high sensitivity. There is a practical limit in the ultraviolet region for measurement of samples in serum because of light absorption by proteins and other components. Thus, convenient wavelengths are those in excess of approximately 320 nm. Longer wavelengths can be used with less sensitivity. Small particles, that is those with a diameter of less than approximately 0.1 μm, are preferred because of both increased slope sensitivity and reaction rates. For reasons of stability and synthetic convenience, particle sizes greater than approximately 0.03 μm are preferred. In general, particle size range of 0.03-0.1 μm can be utilized in the particle reagent of this invention. Shorter wavelengths, such as 340 nm, give larger signal differences than longer wavelengths, such as 400 nm.
For nephelometric detection, the optimum sensitivity can depend not only on particle size and wavelength, but also on the angle of measurement. Nephelometry refers to the measurement of the light scattered at an angle from the incident beam. The size of the particles for optimum sensitivity will have an angular dependence as well as a wavelength dependence.
Other types of light scattering measurements of the agglutination reaction include particle counting, quasi-elastic light scattering, autocorrelation spectroscopy, and measurements of the dissymmetry or the polarization of the particles. These types of measurements provide different constraints for the particle reagents.
In all types of measurements, however, the higher the refractive index of the particle at the wavelength of choice, the higher the light scattering signal.
A preferred way of measurement of immunological reactions utilizing the particle reagents of this invention is by turbidity since no special equipment is required other than a spectrophotometer which is generally available in clinical laboratories. The spectrophotometer measures increased absorbance which is due to the increasing particle size resulting from the agglutination reaction. This increased absorbance is a direct measure of the agglutination caused by the analyte or an indirect measure of the agglutination inhibition caused by the analyte. To optimize the turbidity change which occurs during agglutination, it is important to select the particle size with care.
During the agglutination reaction, the effective particle size increases. For sensitive measurements it is therefore important to choose the wavelength at which the signal change for a given particle size change is optimal.
Because of the importance of the refractive index for turbidimetric detection of the agglutination reaction, core materials are restricted to those which will produce acceptable signal changes for the desired assay sensitivity. For analytes in high concentrations (μg/mL range), the choice is not critical, but for analytes in the nanogram/mL range, particles having high refractive index are necessary. Thus core polymers with high aromaticity and high atomic weight substituents are preferred over aliphatic polymers and, in general, polymers of high refractive indices are preferred over polymers with lower refractive indices.
The inner core of the polymer particles can be selected from a large group of materials with high refractive index. Preferred are those materials which can be prepared by emulsion polymerization in a manner so that the final particle size is controllable and is substantially uniform. Typical polymers utilized in the inner core of the polymer particles have refractive indices greater than 1.54 (at the Na D line, 569 nm) and are listed in Table 1. Since the refractive index is a function of wavelength, the scattering properties will be dependent upon the wavelength of measurement. In general, the refractive index is greater at shorter wavelengths.
TABLE 1______________________________________REFRACTIVE INDICES OF POLYMERSPolymer nD______________________________________Cellulose 1.54Poly(vinyl chloride) 1.54-1.55Urea-formaldehyde resin 1.54-1.56Poly(sec-butyl α-bromoacrylate) 1.542Poly(cyclohexyl α-bromoacrylate) 1.542Poly(2-bromoethyl methacrylate) 1.5426Poly(dihydroabietic acid) 1.544Poly(abietic acid) 1.546Poly(ethylmercaptyl methacrylate) 1.547Poly(N--allyl methacrylamide) 1.5476Poly(1-phenylethyl methacrylate) 1.5487Poly(vinylfuran) 1.55Poly(2-vinyltetrahydrofuran) 1.55Poly(vinyl chloride) + 40% 1.55tricresyl phosphateEpoxy resins 1.55-1.60Poly(p-methoxybenzyl methacrylate) 1.552Poly(isopropyl methacrylate) 1.552Poly(p-isopropylstyrene) 1.554Poly(chloroprene) 1.554-1.55Poly(oxyethylene)-α-benzoate-ω- 1.555methacrylate)Poly(p,p'-xylylenyl dimeth- 1.5559acrylate)Poly(1-phenylallyl methacrylate) 1.5573Poly(p-cyclohexylphenyl 1.5575methacrylate)Poly(2-phenylethyl methacrylate) 1.5592Poly(oxycarbonyloxy-1,4- 1.5602phenylene-1-propyl-butylidene-1,4-phenylene)Poly[1-(o-chlorophenyl)ethyl 1.5624methacrylate]Poly(styrene-co-maleic anhydride) 1.564Poly(1-phenylcyclohexyl 1.5645methacrylate)Poly(oxycarboxyloxy-1,4-phenylene- 1.56711,3-dimethylbutylidene-1,4-phenylene)Poly(methyl α-bromoacrylate) 1.5672Poly(benzyl methacrylate) 1.5680Poly[2-(phenylsulfonyl)ethyl 1.5682methacrylate]Poly(m-cresyl methacrylate) 1.5683Poly(styrene-co-acrylonitrile) 1.57(ca. 75/25) 1.57Poly(oxycarbonyloxy-1,4-phenyl- 1.5702eneisobutylidene-1,4-phenylene)Poly(o-methoxyphenyl methacrylate) 1.5705Poly(phenyl methacrylate) 1.5706Poly(o-cresyl methacrylate) 1.5707Poly(diallyl phthalate) 1.572Poly(2,3-dibromopropyl 1.5739methacrylate)Poly(oxycarbonyloxy-1,4-phenylene- 1.57451-methylbutylidene-1,4-phenylene)Poly(oxy-2,6-dimethylphenylene) 1.575Poly(oxyethyleneoxyterephthalate) 1.575Poly(vinyl benzoate) 1.5775Poly(oxycarbonyloxy-1,4-phenylene- 1.5792butylidene-1,4-phenylene)Poly(1,2-diphenylethyl 1.5816methacrylate)Poly(o-chlorobenzyl methacrylate) 1.5823Poly(oxycarbonyloxy-1,4-phenylene- 1.5827sec-butylidene-1,4-phenylene)Poly(oxypentaerythritoloxyphthalate) 1.584Poly(m-nitrobenzyl methacrylate) 1.5845Poly(oxycarbonyloxy-1,4-phenylene- 1.5850isopropylidene-1,4-phenylene)Poly(N--2-phenylethyl methacrylamide) 1.5857Poly(4-methoxy-2-methylstyrene) 1.5868Poly(o-methylstyrene) 1.5874Poly(styrene) 1.59-1.592Poly(oxycarbonyloxy-1,4-phenylene- 1.5900cyclohexylidene-1,4-phenylene)Poly(o-methoxystyrene) 1.5932Poly(diphenylmethyl methacrylate) 1.5933Poly(oxycarbonyloxy-1,4-phenylene- 1.5937ethylidene-1,4-phenylene)Poly(p-bromophenyl methacrylate) 1.5964Poly(N--benzyl methacrylamide) 1.5965Poly(p-methoxystyrene) 1.5967Hard rubber (32% S) 1.6Poly(vinylidene chloride) 1.60-1.63Poly(sulfides) 1.6-1.7Poly(o-chlorodiphenylmethyl 1.6040methacrylate)Poly[oxycarbonyloxy-1,4-(2,6- 1.6056dichloro)phenylene-isopropyli-dene-1,4-(2,6-dichloro)phenylene)]Poly[oxycarbonyloxybis{1,4-(3,5- 1.6056dichlorophenylene)}]Poly(pentachlorophenyl methacrylate) 1.608Poly(o-chlorostyrene) 1.6098Poly(phenyl α-bromoacrylate 1.612Poly(p-divinylbenzene) 1.6150Poly(N--vinylphthalimide) 1.6200Poly(2,6-dichlorostyrene) 1.6248Poly(β-naphthyl methacrylate) 1.6298Poly(α-naphthyl carbinyl 1.63methacrylate)Poly(sulfone) 1.633Poly(2-vinylthiophene) 1.6376Poly(αnaphthyl methacrylate) 1.6410Poly(oxycarbonyloxy-1,4-phenylene- 1.6539diphenylmethylene-1,4-phenylene)Poly(vinyl phenyl sulfide) 1.6568Butylphenol-formaldehyde resin 1.66Urea-thiourea-formaldehyde resin 1.660Poly(vinylnaphthalene) 1.6818Poly(vinylcarbazole) 1.683Naphthalene-formaldehyde resin 1.696Phenol-formaldehyde resin 1.70Poly(pentabromophenyl methacrylate) 1.71______________________________________
Not all of the polymers listed above can be utilized as the inner core for the particle reagents of this invention since there are additional criteria to be applied to the selection of core monomer materials. Cellulose, for example, is not readily prepared as uniform particle size spheres. Condensation polymers are also not useful since the polymerization process does not lead to spherical particles of the type which can be obtained by emulsion polymerization. Some thermoplastic polymers such as poly(oxyethylene-oxyterephthalate) and some thermosetting resins of the urea-formaldehyde type are not suitable.
The monomers of interest are those which contain vinyl or allyl groups in addition to substituents such as halides, aromatic, heterocyclic, unsaturated or carbocyclic groups which impart high refractivity.
Polymer particles useful for the preparation of the particle reagents of this invention can be prepared preferentially by emulsion polymerization. Staged emulsion polymerization can lead to a core/shell polymer approximating the desired refractive index of not less than nD =1.54. To obtain a polymer of desired refractive index, it is preferred that the shell polymer not exceed approximately 10 parts by weight of the polymer particle.
A convenient way to control particle size of the polymer particles is to first prepare a seed emulsion whose size can be controlled by the amount of surfactant used. After preparation of the seed emulsion, additional monomer and surfactant can be added at a controlled rate to increase the size of the particles in the seed emulsion.
The outer shell polymer of the polymer particle can be prepared from a wide range of ethylenically unsaturated monomers having functional groups capable of reacting with compounds of biological interest. Optionally, the outer shell can also contain other ethylenically unsaturated monomers. The attachment of the shell polymer to the core can be accomplished by graft polymerization of the functional monomer to the residual ethylenically unsaturated groups in the core polymer or the functional monomer can be polymerized around the core to produce a contiguous shell. Preferred monomers include those containing an epoxy group such as glycidyl methacrylate, glycidyl acrylate, vinyl glycidyl ether, and methallyl glycidyl ether. Other functional groups include carboxyl, hydroxyl, amino, and aldehyde.
It is preferable to carry the conversion of the core monomer(s) to substantial completion so that the shell polymer is a homopolymer or a copolymer of known composition rather than a copolymer of unknown composition. Conversions in excess of 98% can be attained by increasing the temperature of the core emulsion to approximately 95� C. at the end of the polymerization. To further reduce the probability of producing particles whose surface is a copolymer of unknown composition, the shell monomer can be added gradually rather than batchwise. In such a manner, the residual core monomer(s) can be consumed during the early stages of the shell polymer formation. When the monomer utilized is one which contains an epoxy group, it is preferred that the shell polymer be a homopolymer although, as a practical matter, monomers of the inner core, up to 10 parts by weight of the outer shell, can be present.
In the case of the shell monomers containing hydroxyl, amino, aldehyde or carboxylic acid groups, care must be taken to avoid the formation of water soluble polymers. Thus, for example, acrolein or methacrylic acid cannot be utilized alone to form a homopolymer shell structure. They can be copolymerized, however, with additional monomers in amounts sufficient to produce water insoluble polymer particles.
It is also possible to modify the outer shell polymer by subsequent treatment to produce a surface capable of covalent attachment by alternative chemical techniques. For example, an epoxy group can be hydrolyzed to form a diol compound capable of reacting with cyanogen bromide which can act as a coupling agent for amine groups in proteins.
Aldehydes can react directly with amines to form a Shiff's base which can be subsequently reduced to form a covalent link. Alternatively, the aldehyde can be oxidized to an acid and carbodiimide can be used for subsequent reaction with amines to form an amide link.
The outer shell is preferably a homopolymer but can contain not more than 10 parts, preferably not more than 5 parts, and even more preferably not more than 2 parts, by weight of the outer shell of the monomers of the inner core. These monomers can be the residual monomers from the polymerization of the inner core.
The particle reagents of this invention can contain several different functional shell materials. A preferred one contains epoxy groups which can be conveniently utilized for the covalent attachment of compounds of biological interest such as haptens, antibodies, proteins or hapten-protein conjugates. Such a reaction results in the particle reagents of this invention.
The preparation of the particle reagents can be carried out as follows: The hapten or proteinaceous material, for example, can be adsorbed onto the surface of the polymer particle, followed by the reaction of the functional group, for example, the epoxide group, under suitable pH conditions, with the complementary functional group of the hapten or the proteinaceous material. A protein which does not interfere with the assay such as human serum albumin can also be included to bind and to block unoccupied sites on the particle surface. Other such blocking agents incude mercaptoethanol, mercaptopropionic acid, cysteine and soluble polymers having amino-functional groups attached. Any unreacted material is then separated from the particle reagent. The conditions of the reaction are such that there should be no substantial crosslinking of particles occurring. That would result in nonuniform reagent particles and unpredictable turbidity changes during the subsequent immunoassay.
There can be two ways of preparing a particle reagent which contains a compound of biological interest or analog thereof covalently attached through a proteinaceous material. The compound of biological interest, such as a hapten, can first be attached to the carrier protein and then attached to the polymer particle. Alternatively, the protein can first be attached to the polymer particle and then the hapten can be attached to the protein. The second approach has the advantage of using the same protein-particle reagent for the synthesis of particle reagents having a variety of compounds of biological interest attached to them. It is also possible to attach the compound of biological interest or its analog directly to the polymer particle.
The surface coverage of the polymer particle by a hapten or proteinaceous material, that is the ratio of the polymer particles to compounds of biological interest, can be varied by reaction time, by dilution of the compounds of biological interest with an inactive diluent or by an additive which aids in the dispersion of the particles. While complete coverage can yield fast agglutination rates, lesser surface coverage can be important in increasing assay sensitivity.
The resulting particle reagent can be suspended in a substantially aqueous medium which can further contain buffer, serum components and surfactants to yield a monodispersed particle reagent for use in light scattering immunoassay.
The present invention is further concerned with an immunologically active, stable particle reagent for use in sensitive light scattering immunoassays for measuring compounds of biological interest. The types of assays include a wide variety of substances in biological fluids, cell and tissue extracts for which an immunological counter reactant can be produced. The compounds of biological interest include serum, plasma, salivary, urinary or milk proteins; drugs, vitamins, hormones, enzymes, antibodies, polysaccharides, bacteria, protozoa, fungi, viruses; cell and tissue antigens and other blood cell or blood fluid substances. Of special interest are those substances for which a quantitative determination is required for the assessment of disease state, as well as various drugs.
The immunoassay can be designed in a variety of ways depending on the type of analyte and the sensitivity required.
For analytes in relatively high concentration such as certain serum proteins, appropriate antibody particle reagents can be used in a direct particle enhanced turbidimetric immunoprecipitation assay. The method of this invention provides increased detectability over conventional immunoprecipitation techniques, corresponding savings in reagent costs, and allows the use of smaller patient sample volumes. Conversely, for the detection of circulating antibodies of interest, the counter reactive antigen or antibody particle reagent can be used in a direct assay.
The inhibition immunoassay method of this invention also requires, in addition to the particle reagent, a bi- or multifunctional agent, hereinafter referred to as an agglutinating agent to cause the agglutination of the particle reagent. It is this agglutination which can be inhibited by the compound of biological interest. The agglutinating agent can be an antibody to the compound of biological interest or its analog or a particle reagent based on a polymer particle, as described above, covalently attached to an antibody of the compound of biological interest. These agglutinating agents are utilized in those situations where the particle reagent utilized in the method contains a covalently attached compound of biological interest or analog thereof.
The agglutinating agent can also be a multivalent conjugate of the compound of biological interest and a protein. Such a conjugate is utilized in situations where the particle reagent utilized in the method of this invention contains a covalently attached antibody of the compound of biological interest.
For the measurement of haptens, several different assay configurations can be utilized. In one such configuration, antigenic particle reagents can be prepared (either hapten-particle or hapten-protein-particle reagents) and the inhibition of the reaction of these particles with antibodies by the compound of biological interest is determined. The reaction can be performed by direct competition between the particle and the patient hapten for the antibody or by sequential reaction of the hapten with antibody followed by addition of the antigen particle reagent. This configuration can also be utilized for the measurement of certain serum proteins. Antigenic particle reagents can be prepared from analogs of compounds of biological interest; for example oubain can be utilized in particle reagents for the detection of digoxin and fibrinogen can be similarly utilized in assays for fibrin degradation products and fibrinogen degradation products.
Another assay configuration for haptens utilizes antibody particle reagents wherein the agglutination of the antibody particle reagents with soluble multi-haptenic protein conjugates is inhibited by the analyte. Such an assay can also be performed in a competitive or sequential mode. In yet another assay, both antibody and antigenic particle reagents can be present, of the same or differing sizes, and the inhibition by haptens can be performed in a competitive or sequential mode.
The agglutination reaction during the method of this invention can be accelerated by the presence of an agglutinating accelerator. Such an accelerator can be a polyethylene glycol or a surfactant such as sodium dodecyl sulfate. This latter is particularly useful in an assay for digoxin utilizing a digoxin-HSA-particle reagent.
The following examples are illustrative of the invention.
(a) A 3-liter roundbottomed flask, equipped with a stirrer and a thermostated heating mantle, is used for the polymerization which is carried out at 70� C. under a nitrogen atmosphere. The seed emulsion is prepared by adding 50 mL of styrene to 2 L of water containing 6 g of "Gafac" RE 610 (an anionic surfactant available from GAF Corp.) and 2 g of potassium persulfate. After one half of one hour, a monomer feed, consisting of 400 mL of styrene, 4 mL allyl methacrylate, and 1.5 g of Aerosol OT-100 (a dioctyl sodium sulfosuccinate, available from American Cyanamid Co.), is started at the rate of 4 mL/min. After the feed is completed, the emulsion is kept at 70� C. for one hour to insure complete conversion of the styrene. The final solids content is 15.9%, the particle size of the core polystyrene emulsion (determined by turbidity measurements at 546 nm) is 0.067 μm, and the surface tension (determined by a tensiometer using the du Nouy Ring method) is 65 dynes/cm2.
(b) A 300-mL roundbottomed flask is used for the preparation of the shell-core polymer. The polymerization is carried out at 80� C. under a nitrogen atmosphere. 200 mL of the core polystyrene emulsion (Example 1a) is added to 50 mL of water containing 0.2 g of potassium persulfate and 0.2 g of anhydrous potassium carbonate, followed by the addition of 3.9 mL of glycidyl methacrylate at a rate of 0.1 mL/min. After 45 min the mixture is cooled. The final shell-core polymer has a particle size of 0.069 μm.
(a) A 3-liter roundbottomed flask, equipped with a stirrer and a thermostated heating mantle, is used for the polymerization. Styrene is purified prior to polymerization by passing through a column packed with basic alumina. The polymerization is performed at 70� C. under a slow stream of nitrogen.
The polymerization is started by adding 45 mL of styrene, 5 mL of ethylene glycol dimethacrylate, 50 mL of a 30% solution of sodium dodecyl sulfate in water, and 2 g of potassium persulfate to 2 L of deionized water. This mixture is allowed to polymerize at 70� C. for 20 min. At this point, the particle size is 0.021 μm and the surface tension is 38.8 dynes/cm2, indicating that substantially all of the surfactant is utilized for particle stabilization.
The particles are then grown to a final size of 0.043 μm by gradually adding 400 mL of styrene and 10 g of "Aerosol" OT-100 at a rate of 4 mL/min. The final size is predicted to be 0.044 μm, based on the initial particle size and the volume of added styrene.
590 mL of seed emulsion, prepared above, is added to 1510 mL of deionized water containing 1.5 g of potassium persulfate and is heated to 70� C. When the mixture reaches 70� C., 340 mL of styrene and 3.4 g of "Aerosol" OT-100 are added at a rate of 4 mL/min. When the feed is complete, the temperature is increased to 95� C. for 0.5 h to insure high conversion of the monomers. The conversion is 98.4% complete, as measured by gas chromatography of an ether extract of the emulsion. The final core size is 0.070 μm. (The predicted value is 0.069 μm, calculated from the initial size and the volume of styrene added.)
(b) 200 mL of water, containing 2 g of potassium carbonate and 2 g of potassium persulfate, is added to the core polymer prepared in (a) above and the reaction temperature is adjusted to 80� C. 50 mL of glycidyl methacrylate is then added at a rate of 1.5 mL/min. A total of 45 min is allowed for the shell polymerization. The final particle size is 0.71 μm and the glycidyl methacrylate conversion is 97.3% (using a gas chromatographic measurement as with the styrene). The final styrene conversion appears to be complete since no styrene is detectable by chromatography.
A 300-mL roundbottomed flask, equipped with a distillation head and a mechanical stirrer, is utilized. 200 mL of water containing 0.5 g of potassium persulfate, 0.5 g of trisodium phosphate dodecahydrate, and 1.5 g of sodium dodecyl sulfate are heated to 70� C. under a nitrogen atmosphere. A seed emulsion is formed by adding 4.5 mL of styrene and 0.5 mL of ethylene glycol dimethacrylate. After 30 min the seed emulsion has a particle size of 0.021 μm and pH of 8.5. A solution of 20 g of vinyl carbazole and one gram of "Aerosol" OT-100 in 10 mL of dichloromethane is then added at a rate of 0.1 mL/min. The dichloromethane is removed by distillation as soon as it is added. After the core emulsion is complete, 0.1 g of potassium persulfate in 10 mL of water is added, and then 2.5 mL of glycidyl methacrylate is added at a feed rate of 0.1 mL/min. 45 min is allowed for the polymerization. The final particle size is 0.041 μm. The final solids content is 10.5%.
(a) The procedure of Example 1(a) is utilized as follows. To 2 L of water containing 2 g of azobisisobutyramidine hydrochloride are added 50 mL of styrene and 2 g of cetyl trimethyl ammonium bromide and allowed to polymerize for 30 min. Then, a mixture of 200 mL of styrene and 2 mL of allyl methacrylate is added at a rate of 4 mL/min. After the addition of 100 mL, and again at the completion of the addition, 0.75 g of cetyl trimethyl ammonium bromide is added. The final solids content is 10.5% and the particle size is 0.106 μm.
(b) A mixture of 200 mL of the core emulsion prepared in Example 4(a) above, 0.2 g of azobisisobutyramidine hydrochloride, and 0.2 g of sodium acetate (anhydrous) dissolved in 10 mL of water is heated to 70� C. under a nitrogen atmosphere. After the temperature is stabilized, 3 mL of glycidyl methacrylate is added at a rate of 0.1 mL/min. 45 min is allowed for the polymerization. The final emulsion has a surface tension of 48.5 dynes/cm2.
(a) Attachment of Fibrinogen to Polymer Particles
A solution containing 25 mg of fibrinogen, 225 mg of human serum albumin (HSA), and 6 mL of polymer particle latex prepared as in Example 4 above in a total volume of 250 mL of 0.015 M tris buffer, pH 8.0, was incubated for 3 days at 4� C. The particles were separated by centrifugation and resuspended in 250 mL of 0.015 M phosphate buffer, pH 8.0, containing 0.1% (w/v) HSA. The mixture was warmed to 70� C. for one hour and then cooled to 4� C. The particles were again separated by centrifugation and resuspended in 240 mL of 0.015 M phosphate buffer, pH 7.8, containing 0.1% (w/v) sodium dodecyl sulfate (SDS). They were again separated by centrifugation and resuspended in 325 mL of 0.015 M glycine buffer, pH 7.7, containing 0.1% (w/v) HSA, 0.1% (w/v) lithium dodecyl sulfate (LDS), and 0.1% (w/v) thimerosal.
(b) Assay for Fibrinogen
The assay was performed at 37� C. on the aca™ discrete clinical analyzer (E. I. du Pont de Nemours and Company). Standards were prepared by adding purified human fibrinogen (available from Kabi Diagnostica) to normal human serum; the zero standard contained 5.0% (w/v) HSA in water. 200-μL samples of each of the standards were added to 4.80 mL of 0.15 M phsophate buffer, pH 7.8, in the filling station of the instrument. 0.05 mL of fibrinogen polymer particle latex prepared in (a) above, 0.125 g PEG-6000, 5 mg SDS, and 6 mg dithioerythritol (DTE) were added at breaker-mixer I, followed by the addition of 0.019 mL of rabbit anti-human fibrinogen antiserum (available from Cappel Laboratories) 3.5 minutes later. The change in turbidity was measured at 340 nm 39 seconds and 56 seconds after antiserum addition. Table 2 shows the rate of change in abosrbance at 340 nm in milliabsorbance units/minute (mAu/min) as a function of fibrinogen concentration.
TABLE 2______________________________________Inhibition of Turbidity by FibrinogenFibrinogenConcentration Rate(μg/mL) (mAu/min at 340/nm)______________________________________ 0 12310 9620 7140 5860 49100 37______________________________________
The assay was performed as described in Example 5(b) above, except that the standards were prepared by adding fibrinogen degradation products to normal human serum. Fibrinogen degradation products were prepared by degrading 200 mg of purified fibrinogen with 25 CU (casein units) of plasminogen, activated by 500 U of streptokinase at 37� C. After 1 hour, the reaction was terminated by the addition of soybean trypsin inhibitor to a final concentration of 1 mg/mL. The zero level standard consisted of 5% (w/v) HSA in water.
Table 3 shows the rate of change in absorbance at 340 nm as a function of fibrinogen degradation products concentration.
TABLE 3______________________________________Inhibition of Turbidity byFibrinogen Degradation ProductsFibrinogenDegradationProducts Rate(μg/mL) (mAu/min at 340/nm)______________________________________ 0 12410 9620 7540 6660 60100 50______________________________________
Since fibrinogen and its degradation products share antigenic determinants, it is possible to use polymer particles with attached fibrinogen for the measurement of fibrinogen degradation products.
The assay was performed as described in Example 5(b) above, except that the standards were prepared by adding fibrin degradation products to normal human serum. Fibrin degradation products were prepared by allowing a fibrin clot to form from 200 mg of purified fibrinogen and then degrading it with 5 Sigma units of human plasmin at 35� C. for 96 hours. The zero level standard was water. Table 4 shows the rate of change in absorbance at 340 nm as a function of fibrin degradation products concentration.
TABLE 4______________________________________Inhibition of Turbidityby Fibrin Degradation ProductsFibrinogenDegradationProducts Rate(μg/mL) (mAu/min at 340/nm)______________________________________ 0 14220 10840 8460 6180 56100 37______________________________________
Since fibrinogen and fibrin degradation products share antigenic determinants, it is possible to use polymer particles with attached fibrinogen for the measurement of fibrin degradation products.
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Wednesday, August 1, 2012
If you would like a shot at serving on the Georgetown County School Board, filing for five of the nine seats starts Wednesday.
The seats that will be on the November ballot are now held by Sarah Elliott (District 1), Sandra Johnson (District 3), Zelma Carr (District 4), Elery Little (District 5) and Teresa Bennani (District 6).
Bennani has announced she is not seeking another term but County Elections Director Donna Mahn said she has been contacted by Pawleys Island resident Richard Kerr who said he is seeking that seat.
It has been a privilege and honor to serve the Pawleys Island community and the citizens of Georgetown County, Bennani said in a letter to the editor that can be found on Page 15A of todays paper.
She also said she feels Kerr, who ran for the board in 2008 and 2010, would be an asset to the panel.
I think he would make a good candidate and serve the area well, Bennani said.
Kerr said he has been involved in the schools for the past few years because he has a 12-year-old in the school system.
He said he feels the school board could use some people who have been in business and have management talent.
Mahn said both Elliott and Carr have told her they are seeking another term. Little told the Georgetown Times Thursday he also wants to serve another four years.
I think things are going well and we need to keep it going, Little said.
Filing for a seat on the board begins at noon Wednesday and continues until noon Aug. 15.
The elections are non-partisan and there is no filing fee.
Anyone wanting to file can stop by the Voter Registration Office at 303 North Hazard Street or call 546-3339 for further details.
By Scott Harper
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Things I liked:This scope feels "well made". Only the test of time will tell. I wish there was an auto off on the lighted rec. My son left it on the first time he looked through it. (Though, do you really need the lighting in an airsoft war?)
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- Willamette
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- Services & Resources
- Faculty Assistance Services Team (FAST)
What is FAST?
WITS employs a group of students who have training, research skills and WITS staff support to help faculty with integrating technology resources into their teaching and research. FAST students work on a wide range of tasks including:
- Developing or upgrading faculty web pages
- Scanning images and documents for class and online presentations
- Creating archives of digital materials
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- Using blogs and wikis
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|Al Monte
|Diary Entries
April 28, 2006
Hi, my name is Al Monte. I am a junior, history major from Philadelphia, Pa. Rowing started for me when I was a freshman in high school and has been a driving force in my life ever since. Rowing is a sport where only the strong survive...literally! With nearly 20 hours per week revolving around the sport, drive, dedication and commitment become paramount among team members. Rowing becomes a lifestyle choice because the sport itself becomes almost all-consuming. It takes a certain type of individual to be on a rowing team because every part of your day from September through May revolves around your next practice and your commitment to the team. Eating and sleeping right become essential in order to maintain one's competitive edge. While rowing is a very team-oriented sport, the pressure on the individual is immense. Each and every team member is dependent on one another to reach and maintain an incredible level of fitness. Whether it be an extra morning workout, lift, or even just regular afternoon practice, every person is asked to perform at their best every day. No individual can win a race single-handedly, and no crew can win a race unless everyone in the boat is as committed as the person in front of and behind them. This is where training steps in and team camaraderie is formed. Members of a rowing team spend so much time together that a strong bond of mutual respect is created. Each team member is aware of what everyone else is going through because we are all going through it together; this forms the basis for that bond, a bond which carries each crew to the finish line. This bond culminates with our annual spring training trip to Gainesville, Ga., home of the 1996 Olympic rowing venue, where we spend seven days preparing for the spring season.
Our spring season officially started on March 18, in Camden, N.J., at the Jesuit Invitational Regatta. This regatta hosts programs such as Georgetown University, Boston College, St. Joseph's University, Fordham, Fairfield and Loyola (Md.) Universities, and of course the College of the Holy Cross. This season opening regatta remains the focus of every winter workout because of the tough competition faced here and also the fact the Holy Cross has never won the Jesuit Cup, the trophy provided to the winners of the men's varsity eight event. After coming off of a very strong season last year with medals at the New England Rowing Championship and the ECAC National Invitational, a 10th place finish at the Eastern Sprints, a prestigious top-tier regatta, as well as being ranked 16th on the U.S. Rowing National Collegiate poll, we entered our season opener with much confidence. We knew the battle would be between ourselves, Georgetown and St. Joe's. With 1000 of 2000 meters to go in the race we sat one boat length down to both Georgetown and St. Joe's. Remaining calm, we kept the focus within our boat and moved into second place, defeating St. Joe's by just over two seconds while simultaneously falling to Georgetown by five seconds. Obviously, this was not the outcome that we had hoped for, but the maturity that our crew showed was the crowning achievement of the day. The varsity lightweight eight and second varsity eight finished third behind two very strong crews from Georgetown and St. Joseph's. Later that afternoon, after very intense morning racing, we went into battle yet again against the University of Delaware. The main focus of this dual was the varsity lightweight eight race in which a team bid for the lightweight events at the Eastern Sprints was at stake. The winner of the varsity lightweight eight would then be eligible to participate in the Eastern Sprints Regatta in May. The Holy Cross lightweight eight unfortunately was unable to defeat the University of Delaware and lost their team bid to the Sprints. In other racing, the varsity heavyweight eight, my boat, and second varsity heavyweight eight were victorious over a very much improved Delaware heavyweight squad. While not the results we were looking for, this proved to be a strong start to the season.
On March 25, our team began its dual racing season, taking on crews from the University of Rhode Island and Boston College. We swept all events except the second freshman eight, which was edged out by only two seconds. The following week, the Holy Cross men went into battle yet again against NERC foes Wesleyan University and USCGA for the perennial awarded Sullivan Cup. The team again came out of this meeting unscathed winning all events, while retaining the Sullivan Cup, the trophy awarded to the winner of the men's varsity eight event.
Our first championship race of the season came on April 2 with the Worcester City Championship. This event included crews from WPI, Clark, Assumption, and of course Holy Cross. This race has been an important event since the inception of Holy Cross rowing back in the 1960s because of the friendly rivalry that has existed between WPI and Holy Cross in the men's varsity eight event. We rowed a very solid race against a much improved Tech crew winning by nearly 10 seconds. This victory marked the sixth year in a row Holy Cross has won the event. We also were able to capture victories in the varsity four-with-coxswain, second varsity eight and the first freshman eight. All in all, it was a great day for Holy Cross rowing.
For the first time on the weekend of April 8 and 9, we traveled to the nationally renowned Knecht Cup Regatta, held annually in Camden, N.J. This meet would prove to be filled with far more competition than we had faced up until this point, with 16 other varsity programs competing the varsity eight event. After winning our preliminary heat, we secured ourselves a top seed in the grand final, the final event where the top six out the 16 crews would race in order to find the champion. After rowing what I would consider a sub-par race, we came up about four seconds short of beating perennial power-house Temple University. The highlight of the day would come with the freshmen eight grand final where the entry from Holy Cross would come out victorious over a very tough crew from Lehigh University. The lightweight varsity eight also competed in the regatta coming in third in their division behind St. Joseph's and Georgia Tech. While the weekend was a mix of both high and low points, we had to refocus our attention to our next race with NERC foes Trinity College and the University of Massachusetts-Amherst. This week of practice focused on regaining our composure which we lacked in the finals of the Knecht Cup.
This race would prove to be one of our closest races of the season. Trinity College, ranked 12th nationally on the U.S. Rowing Collegiate Coaches Poll, is most definitely our biggest rival in the New England Rowing Conference. Last year our crews were within one to three seconds of each other on any given day, so I knew this race was going to be a barn burner! I was proven right. In the varsity eight event, the separation between our crews was a mere 1.4 seconds. In the second varsity eight, the margin was 1.6 seconds. Crews from the University of Massachusetts were represented in both events as well, both securing third place finishes. While these were not the results we wanted, as a team we then knew where we stood in relation to our biggest rival. Also, I was pleased because my boat regained its maturity and composure, battling Trinity with great intensity every stroke but doing it with technique. We will next see Trinity at the New England Rowing Championship on May 7, and again for the ECAC National Invitational on May 13 and 14.
Our last regular season regatta was last weekend against crews from Tufts University, Colby College, Connecticut College and Ithaca College. Again, the crews from Holy Cross came out on top in all events except the varsity four-with-coxswain, who rowed a very tough race against Connecticut College's top four rowers, losing by only two seconds. That afternoon, the Holy Cross crews would go into battle again against crews from RIT and UNH. On the varsity level all of our crews were victorious.
We have had impressive results thus far this season, and I could not be more excited to enter the championship season as a member of this crew!
Until Next Time,
Al Monte


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Funding the Future Campaign
Sarah Bush Lincoln Health Foundation supports the Health System by creating a culture of philanthropy. The not-for-profit Foundation is deeply rooted in the community, raising funds and collaborating with others to support the Health System's mission to provide exceptional care for all and create healthy communities.
The Foundation is currently raising funds to support the Funding the Future Campaign. Funding the Future supports Healthy Kids Initiatives, which are designed to reduce childhood obesity and improve the health and wellness of kids, and helps fund the Master Facility Plan which will renovate and expand the Health Center.
In our seven-county service area, more than 9,000 children are overweight or obese, which translates into 33 percent or one in three kids who are battling obesity. We know that when children are overweight, they tend to carry that into adulthood, and are at risk for developing chronic health issues like heart disease and diabetes. It's essential we partner with schools, parents, and local organizations to establish Healthy Kids Initiatives which are targeted at reducing obesity and increasing physical activity. We have the opportunity, responsibility and power to act now, to improve the health of children living in our region.
Additionally, we are preparing Sarah Bush Lincoln for the future by planning a $48 million Master Facility Plan, which will expand and renovate the Health Center. All adult inpatients will have a private room in which to receive care. Access to emergency care will be improved. More than 8,000 total square feet will be added to the Emergency Department, allowing SBL to expand from 19 semi-private treatment stations to 27 private rooms. Surgical suites will be enlarged, laboratory services will be expanded and relocated, and public areas will be modernized. This Master Facility Plan will renovate 120,000 total square feet of the 34-year-old facility and take the community-minded organization well into the future. Our goal is to provide trusted, compassionate, high-quality care for generations to come and to improve the health of children in our region.
The Campaign Goal is to raise $8 million. Of the $8 million,
- $5.5 million will help renovate and expand the Health Center, and
- $2.5 million will help develop Health Kids Initiatives, designed to reduce obesity and improve the health and wellness of kids.
Campaign Committee members represent the community we serve.
Learn more (2.8 MB) about the Campaign.
Learn more about Health Kids Initiatives
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Funding the Future Campaign Video
For more information about the Sarah Bush Lincoln Health Foundation and philanthropic opportunities, call 258- or 348-2511, email firstname.lastname@example.com, or mail to:
Sarah Bush Lincoln Health Foundation
1000 Health Center Drive
P.O. Box 372
Mattoon, Illinois 61938-0372


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The popular Scribner Writers print series is now available online in eBook form!
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In this elegant, contemporary fountain, water flows down a tempered bronze mirror into a decorative dark copper basin filled with polished river rocks. Designed for both indoor and outdoor use and including an in-line filter, adjustable flow valve and a submersible pump. Easy assembly; no tools required. From Bluworld fountains.
Shipping and Delivery Information - For item EUT1617 if ordered by 1 pm Pacific Time


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At the news of Kang San's imminent financial ruin, Hae Joo goes to Do Hyun and promises to develop the azimuth thruster at Cheonji if Do Hyun will release the seizure of Kang San's company. Chang Hee asks his father, Gee Chul, for help in winning over Geum Hee to his marriage to In Hwa. Jung Woo finds a National Security agent who previously worked with Do Hyun, and Dae Pyung goes to find out the truth about the death of his son, Kang Woon. Dae Pyung then confronts Do Hyun.
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The First Mate Team


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Forty years ago, when Janet Yellen, chairwoman of the US Federal Reserve, was an economist at Harvard University, she was interested in the film Five Easy Pieces. She noted the scene in which a diner waitress refuses to bring Jack Nicholson's character an omelette with coffee and wheat toast because it serves omelettes with cottage fries and rolls. "I know what it comes with, but it's not what I want," he retorts.
© The Financial Times Ltd 2015 FT and 'Financial Times' are trademarks of The Financial Times Ltd.


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WEST SACRAMENTO, CA - Now that Gov. Jerry Brown and the California Federation of Teachers' new compromise tax initiative can start gathering signatures that brings the total number of measures circulating throughout the state to a whopping 69.
Most campaigns are paying workers about $1 per signature they get or an hourly rate of $10 to $12.
"Yes, there's a lot of competition out there," Signature Gatherer Alberto Richard said. "On some days when I work, I can see up to five or six different ones right out here with us."
But since there's so much competition, Brown and teachers group are starting pay at $3 a signature, a pretty high price.
On top of that, they must get nearly a million valid signatures by early May in order to qualify for the November ballot.
And as that deadline approaches, pay could jump up to $5 or $6 a signature.
"We're committed. We're committed to doing whatever it takes in order to get this measure qualified," Senate President Darrell Steinberg, D-Sacramento, said.
Government groups, though, hate the idea of paying so much money for signature gathering.
Citizen initiatives used to be an all-volunteer campaign; however, critics said the process has been hi-jacked by well-financed groups, spending $2 million to $3 million to get their idea on the ballot.
"If you're an everyday citizen, your ability to access the ballot and put an initiative on there is very, very difficult," California Common Cause Phillip Ung said. "You would need either a large special interest backer or a millionaire."
But with the labor market still bad, job seekers say $3 a signature is looking good.
"It's not a lot of money, but it is helpful because when you look at everything that's going on in America with the economy and job situation," Job Seeker Gerald Mayo said. "It is helpful."
Nannette Miranda


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School Bus Pre-Trip Study Guide
Remembering every item for a CDL pre-trip inspection isn't easy, but this school bus pre-trip study guide has proven to be an indispensable aid for new drivers. School transportation directors use this bus pre-trip study guide to get new bus drivers trained and up to speed quickly.
Stop struggling with the school bus pre-trip inspection - get this guide now!
School Bus Pre-Trip Study Guide Includes:
Whether you want to become a bus driver yourself or happen to be a school transportation director, this guide will help relieve the pre-trip headaches that come with getting a CDL. Order today and we will ship this handy study guide to you for FREE.
The official eGears School Bus Pre-Trip Inspection Study Guide helps reduce the stress of preparing for the CDL pre-trip test. Drivers can study more efficiently, waste less time retaking the CDL test, and get to work sooner.
Order the School Bus Pre-Trip Inspection Study Guide with FREE priority shipping!
By: Chris D. from Milford, Ohio on 1/20/2014
Excellent complete and systematic in its approach to the "pre-trip" Pick this up now!
By: Salcedo from Los Angeles CA on 8/23/2012
Well put together, easy to read and follow. I can't go wrong with E-Gears at my side.
By: CDL from Stuart FL on 8/13/2012
This is a good CDL checklist
By: Driver from Ann Arbor MI on 7/15/2012
This is great - just what we were looking for. The only thing I would add to it is to make check boxes by each item. Easy for the driver to initial as he checks.
By: Marc from MS on 8/21/2011
I used it as a visual aid and study guide every time I went over the pre-trip leading up to the test. The proctor finally told me, "ok you can quit naming the parts."
By: Patty from birmingham on 8/16/2010
i got this and the brake check and used them both alot, they helped me so much thanks.
School Bus Pre-Trip Inspection Video - Type C
School Bus Pre-Trip Inspection Video - Type D
School Bus Pre-Trip Inspection - DVD Training


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|all photos by Jeremy Kramer
Engagement Photos #2
Shared by Mallory Makes Things at 10:53 AM
Topics: Brian, photography, wedding
4 comments:
- Anonymous10/12/12, 11:31 AM
you look older than him. sorry!ReplyDeleteReplies
I know it, he has such a young face! He's about two years older than I am though, so it's totally fine :)Delete
Aww, these photos are so sweet and fun! Sorry about the bird poop...glad you recovered from it :)ReplyDelete
Aw you two are a great couple, this pics are lovelyReplyDelete
Subscribe to: Post Comments (Atom)


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This year, Scottish Citylink is supporting men's health charity Movember by placing moustaches on the front of several coaches.more
We at Citylink are aware that keeping our staff members hydrated will aid them to perform at their very best throughout the work day. more
Scottish Citylink is Scotland's leading provider of express coach services. Each year, over 3 million passengers travel with us to more than 200 destinations on our fleet of blue and yellow coaches. Our aim is to provide you with a quality, reliable and safe service, delivered with courtesy and value for money.
Position: On-Bus Host/Hostess required
Location: Aberdeen
Responsible to: Customer Service Manager
Main Purpose: To provide hospitality on board Citylink Gold services.
Key Tasks:
Person Specification:
Hours of Work : 43 hours per week
Rate of Pay : Rate begins at £7.00 p/h increasing dependant on hours worked. Overtime available.
Please email covering letter and CV to: firstname.lastname@example.com and quote ref: ABNGOLD
Closing Date: 12noon Friday 11th May.
Careers page


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|« Back to Article
Missions to host pair of job fairs
Staff Report : March 11, 2014 : Updated: March 11, 2014 11:20am
Photo By Billy Calzada/San Antonio Express-NewsFans watch San Antonio Missions starting pitcher Eddie Bonine warm up before Game 2 of the Texas League Championship Series against Arkansas at Wolff Stadium on Wednesday, Sept. 11, 2013.
More Information
Missions website
SAN ANTONIO — The San Antonio Missions will host the first of two job airs on Saturday, March 15, from 10 a.m.-2 p.m. at Wolff Stadium.
The first event will be for jobs with Diamond Creations, the Double-A baseball team's concession service. Applications will be accepted for the following hourly positions — office manager, expeditors, cooks, cashiers and dishwashers. Apply at the Missions' office on the first-base side of the stadium.
On March 22, the Missions will conduct another job fair from 10 a.m.-1 p.m. Positions available include box-office employees, promotion crew members, customer service representatives and fun-zone attendants.


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I have a soft spot in my heart for Seth Green. Not because he's "cute," not because he does voice-overs on Family Guy, but because he played the part of Richie Tozier so damned well on the television production of Stephen King's It way back in the day. He rocked Richie.
Anyway, Seth has gone and tied the knot with his new bride, Clare Grant. Grant, the model/actress, gained her fame appearing in Black Snake Moan with Christina Ricci and currently stars in MTV's $5 Cover, a show about bar-and-club-hopping wannabe musicians.
The two were engaged on New Years' Eve and married this past weekend at George Lucas' Skywalker Ranch in Northern California.
Richie Seth. Congrats.


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Out of Stock
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text: There are a ton of positives in coaching. We get to work with some fabulous kids, talented athletes, the competition, the opportunity to stay in the game, etc. There are a few negatives as well. Poor fields, poor/uneven talent, bad administration. You name it. One of those things I hear all the time as a negative are the parents. Personally I have had a few run ins with parents that ruined my day but in general I've been lucky. I have always made it clear what kind of behavior was expected from them and they have, for the most part behaved themselves. I'd like to hear about your experiences with parents over the years. I'll share one myself to get it started. Just this year, while coaching high school ball, our program came up against a very organized group of parents who seemed to be bent on making the coaches lives difficult. Like I said, I have always been pretty lucky and rarely had parental issues. But this group was ridiculous. They would actually have meetings and come up with a plan on how to get what they wanted that involved multiple parents approaching/calling/e-mailing the coaches and athletic director with there issues. Doesn't sound like much but they would do this over several says, no one parent making there complaint at the same time/day, and all with the same complaint worded slightly differently and phrased as though it was there concern only. Some would be real nice about it but only after the nastygrams came through. Sort of a good cop bad cop thing I guess. We didn't clue in on it right away but some of the other parents who thought it was silly let us know what was up. It actually became kind of comical after awhile.


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Step One: Prevent Equine Insects
Most insects thrive in barns and pastures. Flies flourish in moist, dirty manure piles. Mosquitoes relish standing water in troughs and buckets. Ticks seek longer pasture grasses. It makes sense then that one way to control most species of insects is to eliminate the locations in which they find refuge. Ideal preventive measures include:
Step Two: Reduce Insect Exposure
Step Three: Protect Individual Horses
The Importance of Insect Control
Worse, many insects are carriers of potentially serious diseases. Flies are known to transmit typhoid, dysentery, and tuberculosis. Mosquitoes carry West Nile Virus and equine encephalitis. Ticks can spread Lyme disease. True, some insect-borne diseases have no effect on your horse. However, they can affect you and your family.
Because of their resilience, insect control may seem like a daunting task. However, working to eliminate suitable insect habitats, control the environment around your barn and pasture, and individually protect your horse will offer the best protection possible.


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The Star-Ledger NewsLocal NJ politics, crime & Statehouse coverage from The Star-Ledger
A damaged brain drives a man to obsessively create art.
Learn about Jon Sarkin by viewing the story, photos and video.
Latest user-submitted photos:
- Share the videos you've shot - it's easy!
Please go to http://www.nj.com/starledger/index.ssf?topstories for top daily news and update your bookmarks.
Most residents shun developer's offers
Al Viviano got the letter three weeks ago and immediately gave it to his lawyer, flatly rejecting the offer it contained to swap his Long Branch home for a new condominium in the city.
Rose LaRosa received a similar letter from the developer, and like Viviano, said she's got no intention of giving up her home.
Developers hoping to acquire 36 homes and vacant parcels in the north end of Long Branch for the next phase of the city's oceanfront redevelopment are offering the owners financial incentives to sell so the city will not have to resort to obtaining the properties through eminent domain.
The properties are on Marine Terrace, Ocean Terrace and Seaview Avenue, and in most cases, the owners have refused offers to swap or sell. Several, however, have decided to negotiate with the developer.
Yesterday, U.S. Rep. Frank Pallone (D-6th Dist.) visited the neighborhood to announce his plan to introduce legislation that would prohibit the use of eminent domain in the taking of private property in all but certain extenuating circumstances.
But Pallone, who grew up in Long Branch and maintains a district office in the city, also said the effort could be too late to help a coalition of homeowners who are trying to keep their properties.
The coalition, called the Marine Terrace, Ocean Terrace, Seaview Avenue Alliance, or MTOTSA, represents 24 property owners. The group insists the city is improperly using eminent domain -- the practice that gives government the authority to take private land for public purpose -- to force them out of their modest seaside homes and replace them with about 170 luxury condominiums and townhouses they can't afford.
Although the city has already obtained 120 properties along the oceanfront for its massive redevelopment, this is the first time the developer, Applied Development Co. of Hoboken, has offered a package of financial incentives.
The offer applies to people who live full time on Marine Terrace, Ocean Terrace or Seaview Avenue or use their house as a second home. The offers do not apply to those who rent their homes.
Of the 36 properties slated for the wrecking ball, only 16 qualify for the incentives, city Administrator Howard Woolley Jr. said. None of the 16 property owners has accepted a deal, though a few are negotiating with the developer, he said.
"The city and the developer want to make as many negotiated transactions as possible," said Greg Russo, vice president of Applied Development. "The city has made it clear they want eminent domain to be a last resort. That's why we are offering these various incentives."
In at least one case, a homeowner is negotiating with the developer to "swap" his property for a new condominium.
Woolley said the home, assessed at $330,000, has been appraised at $625,000 and the developer has offered to buy it for more than $800,000. The owner now pays about $7,755 a year in taxes.
As part of the deal, the owner would be able to purchase a new condo for $500,000, the taxes on which would be about $11,750 a year, he said.
But a fund set up by the developer would pay $5,000 of the tax bill for 10 years, even if the taxes increase. The owner would be responsible for the rest. After the 10 years, the homeowner would pay the entire tax bill.
The developer's fund would also pay all maintenance fees, estimated to be about $4,000 a year, for 10 years.
If homeowners don't want to swap their properties, but agree to sell voluntarily, the developer will pay $72,000 on top of the price of the house.
"The developer has been more than fair in the offers to the people who have chosen to negotiate," Woolley said.
Russo said his company can be flexible with the offers to suit individual needs -- if they at least agree to talk.
"Several of the members of (the homeowners coalition) won't even sit down and talk to us, while at the same time saying we're not being fair with the offers," he said.
Viviano, 92, is one of them. Viviano, whose father bought the house on Marine Terrace 73 years ago as a summer home, moved in full time 25 years ago. He said he's not interested in a swap because, in his eyes, it would never be a fair deal.
He said the developer offered him $303,000 to sell the house outright, or would have valued the home at $600,000 toward a swap for a new condominium.
"Our squawk is we don't care about the money. We want to stay here," Viviano said.
LaRosa, however, who lives in the Ocean Terrace house her father bought in 1944, said she doesn't discount Pallone's planned legislation, although it will not be introduced before Congress reconvenes in September.
"I am not giving up ever, ever, until the day they pull me out," she said. "I'm hoping a miracle may happen. I really am."
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The studio will be closed from Oct. 29 till Nov.5th because of urgent sun related business in California.
A Heart A Day will still get some love though…
Archive for October, 2009
Out of the office.Wednesday, October 28th, 2009
The studio will be closed from Oct. 29 till Nov.5th because of urgent sun related business in California.
Visual CultureSunday, October 25th, 2009
Nice little write-up of aheartaday.com over on the Visual Culture blog.
Great site, btw, check it out!
Screwed.Wednesday, October 21st, 2009
For "The Pour", the New York Times' wine section.
About how some Californian restaurants don't serve Californian wine, as it's too overpowering. Supposedly.
AD: Nicki Kalish
hooked.Wednesday, October 21st, 2009
For an article about new phishing scams on the net trying to lure consumers with
antivirus protection, yet they carry their own malware.
PC World, AD: Beth Kamoroff
SPD AnnualFriday, October 9th, 2009
One of some pieces of mine that got accepted in the SPD Annual this year.
It's for Men's Health, for an article about the penis…
There's more on the SPD site, a few spots for Bloomberg Markets Mag, >click here< >and here<
Donkey BusinessFriday, October 9th, 2009
For TJ Tucker at Texas Monthly.
It's about attempting to find the one liberal voter in the town of Guthrie, TX.
A Heart A DayWednesday, October 7th, 2009
Last week I created a new blog, entitled "A Heart A Day".
I will be posting one image from the Love&Hate series every day (except for the weekends).
So, for your daily dose of Love (and Hate), head on over, comment on stuff you like (or not) and keep checking back…
And spread the luv!


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I work at a public library and I was surprised to find out that it is difficult to purchase an audiobook of The Shining. I contacted the library department that orders materials and was told:
I would like to get it, but Im having problems finding it. MidwestTape and Amazon are out of stock. And I could not find e-audio versions either.
I even checked his exclusive audio publisher Brilliance Audio, but did not have luck.
It seems to me that with Doctor Sleep coming out, there will be a renewed interest in The Shining in all forms. Not sure what can be done about this but thought I would leave a message here and see if anyone has any idea about why this isn't available.


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The Walking Dead
The Walking Dead Season 4 Premiere Date Is…
UPDATE (July 19): The Walking Dead Season 4 premiere was just confirmed at 2013 San Diego Comic-Con. Mark your calendars for Sunday, October 13 at 9 p.m. ET on AMC.
UPDATE: According to a February 27 report in USA Today, production on The Walking Dead Season 4 will begin May 6 in Atlanta. There will be 16 episodes (just like Season 3). Season 4 will reportedly premiere in October 2013, as expected, and they will likely do the midseason break thing again. We're still waiting on an exact premiere date, so just clear every Sunday in October until further notice!
Original story:
AMC's official renewal of The Walking Dead for Season 4 came at the same time as the shocking news that Glen Mazzara would be leaving as showrunner, replaced by Scott Gimple.
It was such a to-do, we forgot to get excited about Season 4. It was always inevitable, but so what? It's still cool! According to a December 9, 2012, story on TheCitizen.com in Georgia, The Walking Dead will be returning to Senoia, Georgia, for Season 4, and pre-production for the show will probably begin in March 2013. Comic book writer/executive producer Robert Kirkman talked to Entertainment Weekly in a February 10 interview and gave them a Season 4 update: "We're on our second week of writing. We're knee deep in it and we start filming in May."
Season 3 also started filming in May. So when will The Walking Dead Season 4 premiere? Seasons 1, 2, and 3 all premiered in October, so there's no reason why AMC wouldn't stick with that spooky undead timeframe. It ain't broke, so don't break it. The returns have gotten slightly earlier each time, too. TWD Season 1 premiered on Halloween 2010. Season 2 kicked off on October 16, 2011. Season 3 premiered on October 14, 2012. If we had to throw down a guess, we'd say Season 4 will premiere on Sunday, October 13. We'll update the intel with the official news when it comes out.
Meanwhile, if you missed The Walking Dead Season 3 finale read our recap here!
Catch up on all kinds of Walking Dead recaps, spoilers, news, videos and polls at Wetpaint.com/walking-dead.


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A friend tried parking his receiver, this is the first time he did it and I never tried so I can't give him any advice. I don't know exactly what method he used but can find out if needed.
But here's 2 pics of it, the left side has a lighter colored area along the top, the rest seems to have come out even. He said he had to lay it on it's side because his pan wasn't deep enough to cover everything if it was placed upright, he didn't say which side was down though.
So can anyone tell what might have happened to cause the difference in color?


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Director Position Responsibilities
IFC Director Positions Responsibilities (Appointed)
External Relations Director:
- Serve as Co-Director with CPC External Relations Director
- Meet monthly with Chapter Public Relations chairs.
- Write, print, and distribute newsletters including, but not limited to, the Greek Life newsletter and bulletin.
- Assist in IFC fundraising and service events by collaborating with the Vice President of Programming and Fundraising.
- Facilitate and coordinate the Last Lecture Series.
- Host network events with interest groups on campus (i.e. Conservatory, sports teams, etc.).
- Establish and maintain relations with on campus and community organizations.
- Attend all IFC open business meetings, and Executive Board meetings upon request
Greek Sing Director:
- Serve as Co-Director with CPC Greek Sing Director.
- Coordinate and plan schedule of events for annual Greek Sing competition.
- Serve as Greek Sing committee's chair, organizing and overseeing application process and delegating committee responsibilities
- Organize and facilitate meetings with chapter Greek Sing Directors.
- Attend all IFC open business meetings, and Executive Board meetings upon request
Share |


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TAMAQUA — Rifles racks here at Ed's Sports Shop in Tamaqua are usually full.
But now as the president prepares to announce stricter regulations for gun control, they're selling more quickly than ever.
About 150 assault rifles are now all sold.
"In the past month and a half, two months, it`s been unbelievable, everything has been selling. No matter what, people are coming in they`re buying it. They`re concerned as to what`s going on in the country," said Edward Kennedy, owner of Ed's Sports Shop.
The White House is expected to announce about 19 executive actions on guns in the wake of the Sandy Hook tragedy, including a renewal of the assault weapons ban and getting rid of high capacity magazine clips.
Something that frustrates gun owner Nicholas Boyle.
"I think this whole executive order thing is completely negating the whole Democratic process this country was built on. And I think it`s terrible," said Boyle.
Kennedy sells guns every day and believes rules are already strict enough.
"If you have any kind of criminal background you`re not going to get a gun, it`s just not going to happen. So I don`t know how they could strengthen them if that`s what they want to do. Let us know," said Kennedy.
Owners said it`s not just handguns and rifles that are flying off the shelves, these high capacity magazines are selling quick too, and they`re only expecting business to increase.
"Guns in this area are like tools. Just like a mechanic or a baker, everybody, they treat guns as tools, not a mass destruction weapon," said Kennedy.
Richard Magnali is a member of the NRA and strongly believes any new regulations on gun purchases like these won't prevent any more mass shootings.
"And I will say it, Obama`s dancing in the blood of these kids to push his agenda," said Magnali, or Tamaqua.
"If someone`s going to go off the deep end they`re going to do it. You can`t blame the tool," said Boyle.


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Read Me a Story and More @ Foster Library
Submitted by Scribbles on April 14, 2014 - 1:06pm
Early Literacy Workshop
for parents and caregivers of children ages 0-5
Wednesday, April 30 from 6 to 8pm
This ADULTS ONLY event requires advanced registration.
Class size is limited. Sign up at the children's desk or
phone 648-2716 and ask for the children's department.
- Scribbles's blog
- Login to post comments


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The following is a listing of Galesburg Attorneys and lawyers.
If you are looking for lawyers in Galesburg, please choose from the practice areas listed (such as personal injury and criminal). You will then get a list of attorneys in Galesburg. You can browse through the lawyers in the list and find one that suits your needs.
Attorney Locate - The informed way to find Galesburg Attorneys!
Popular Practice Areas for Galesburg Attorneys:


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Offset I O module
Turcks remote I/O system for zone 1 and 2 are used during operation Muelheim for validated connections between he field instrumentations and guidance system. Turck optimized zone 1 remote I/O system excom for application in zone 2. It also expanded system functions with new firmware and a new DTM (Device Type Manager). The modular design device with compact backplane and smaller power supplies increases suitability of installation with lower space in zone 2.
The new firmware and the new DMT enables to operate the excom-system and the connected field instrumentation without prior connection to the process control system. Validated operation and connection between the field installation and the control technology is ensured eliminating any errors from the first point. The user can add new measuring points even during operation.
Other TURCK products
Other products


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I am a 40 year old woman, 2nd pregnancy, with pre-existing high blood pressure currently in my 20th week. I have kept my weight gain to 10 lbs so far, drink lots of water, do not have any of the signs of pre-eclampsia (except pre-existing and my first pregnancy 14 years ago was pre-eclampsia).
Up until a week ago I was also walking 1.5 miles every day to keep the weight down plus the exercise helps control my blood pressure. I was told by my doctor to stop walking due to a 24 hour urine collection that measures the toxins eliminated by the kidneys measured at 89 instead of the average 150.
I can not find any supporting documentation that suggests that exercise has any effect on kidney performance and wonder whether it may be too early to tell me to stop walking. Seems like the benefits would outweigh the problems since I have not officially been diagnosed with pre-eclampsia as of yet. Although I expect my pregnancy could end in bed rest as did my first, I am still very healthy at this point.
What are your thoughts about exercise at this stage? Is there any exercises which I can do? Swimming, Yoga???