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Oxford University
News about Oxford University, including commentary and archival articles published in The New York Times.
Chronology of Coverage
Apr. 12, 2015
Men's and women's rowing crews from Oxford and Cambridge race on same course and day for first time. MORE
Mar. 27, 2014
Oxford and Cambridge women's boating teams, which historically have raced on a different day and stretch of the Thames from the men, will face off this spring for the last time on this course; starting in 2015, women will race shortly before men on championship course on the Tideway. MORE
Mar. 23, 2014
Jennifer Moses travel article on Oxford, England; darting between past and present, bookish and bucolic, she peels back layers of the quintessential college town, home to Oxford University. MORE
Sep. 19, 2013
The Bodleian Libraries Chair Competition announces its winner, which is only the third new chair developed specifically for the Bodleian since 1756. MORE
Jul. 12, 2012
University of Oxford announces a $115 million donation from Michael Moritz, an alumnus and a major Silicon Valley venture capitalist, as the cornerstone of a $460 million fund dedicated to reducing debt for disadvantaged students; the first 100 scholarships are to be awarded in the fall of 2012. MORE
Apr. 9, 2012
Memo from London; annual Oxford-Cambridge boat race along a historic stretch of the Thames in London is disrupted after protester swims directly in the path of two boats to protest elitism of the event; incident revives old national debate over issues of class privilege. MORE
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A Gap Lingers in Taiwan's Wartime Memory
Some say a 1945 air raid on Taipei by American bombers has been ignored by the government, with no official events to mark its anniversary and no physical memorial for the dead.
July 15, 2015, Wednesday
MORE ON OXFORD UNIVERSITY AND: Chiang Kai-shek , Ma Ying-jeou , Mao Zedong , Mitter, Rana , China , Hiroshima (Japan) , Nagasaki (Japan) , Taipei (Taiwan) , Taiwan , Chinese Nationalist Party (Taiwan) , Communist Party of China , Oxford University , Monuments and Memorials (Structures) , Veterans , World War II (1939-45)
Simon Armitage, Oxford Poetry Professor, Finds Inspiration in the Mundane
Mr. Armitage, a former probation officer in Manchester, England, has endeared himself to the public by creating poems out of seemingly ordinary life.
July 11, 2015, Saturday
MORE ON OXFORD UNIVERSITY AND: Armitage, Simon , Colleges and Universities , Great Britain , Poetry and Poets , Oxford University
Letter of Recommendation: The Oxford English Dictionary
To own these books is to dwell alongside your own personal Eighth Wonder of the World.
July 5, 2015, Sunday
MORE ON OXFORD UNIVERSITY AND: Dictionaries , English Language , Oxford University Press , Language and Languages
Help for the Signing-Impaired
In hearing-world contexts in which verbal communication fails, I long to say to my hearing companion: "Do you realize that, when your capability to hear fails you, you are essentially disabled?"
June 3, 2015, Wednesday
MORE ON OXFORD UNIVERSITY AND: Callis, Lydia , Oxford University , Deafness , Disabilities , Ears and Hearing , Sign Language
Rowing Crews Break Gender Barrier in England
The gender barrier in one of England's oldest sporting events was broken Saturday when the men's and women's rowing crews from Oxford and Cambridge raced over the same course on the same day for the first time.
April 12, 2015, Sunday
MORE ON OXFORD UNIVERSITY AND: Rowing , Colleges and Universities , Gender , River Thames (England) , Cambridge University , Oxford University
Rhodes Scholarships Expanding to Include Chinese Students
The effort is part of an international push to reshape the program that for more than a century has sent promising students to the University of Oxford.
March 31, 2015, Tuesday
MORE ON OXFORD UNIVERSITY AND: Rhodes Scholarship , China , Scholarships and Fellowships , Oxford University
Study Reveals Genetic Path of Modern Britons
Researchers found that the modern British population falls into 17 clusters that are all very similar but genetically distinguishable.
March 19, 2015, Thursday
MORE ON OXFORD UNIVERSITY AND: Genetics and Heredity , Great Britain , Nature (Journal) , Oxford University
Named Next President of N.Y.U., Oxford's Leader Inherits Challenges From John Sexton
Andrew Hamilton, a British-born chemist, will take over for Dr. Sexton, who has increased the university's prestige while pursuing contentious campus expansions in New York City and abroad.
March 19, 2015, Thursday
MORE ON OXFORD UNIVERSITY AND: Colleges and Universities , Hamilton, Andrew Jr , Sexton, John E , Oxford University , New York City , New York University
How to Get More Women to Join the Debate, Part II
There were great questions to my original post on the lack of female commenters on the New York Times website. Here are some answers.
March 9, 2015, Monday
MORE ON OXFORD UNIVERSITY AND: Kristof, Nicholas D , New York Times , Oxford University , Women and Girls
The Depression's Unheeded Lessons
Economic leaders made the 2008 financial crisis worse through a combination of misinterpreted history and missed opportunities, a new book argues.
January 11, 2015, Sunday
MORE ON OXFORD UNIVERSITY AND: Eichengreen, Barry , Geithner, Timothy F , Hoover, Herbert Clark , Paulson, Henry M Jr , Romer, Christina D , Hall of Mirrors: The Great Depression, The Great Recession, and the Uses-and Misuses-of History (Book) , Books and Literature , Recession and Depression , Great Depression (1930's) , Economic Conditions and Trends , United States Economy , Oxford University Press , Federal Reserve System , Bernanke, Ben S , Bush, George W
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Posted at: 02/19/2013 6:41 PM
By: Brianna Long
(ABC 6 NEWS) -- It's been a hot issue across the area, and Tuesday the debate over Silica Sand mining went from Southeast Minnesota, to the state capitol.
It was a packed house in room 115 at the state capitol today. Opponents of frac sand mining from across the area, including Winona, Filmore, and Wabasha counties testified at the hearing. People from the sand mining industry were also there. One of the main points of concern was regulation.
Two big questions were posed Tuesday during the joint committee meeting in St. Paul. First, how does silica sand mining affect the environment?
"Regarding water; millions of gallons of water per day will be consumed with polycrylamides for washing. We're already facing a drought in Minnesota. We need to get smart about this," said Jody McIlrath with Save our Bluffs.
"When we mine one of our quarries, we'll be reclaiming it and donating it to the city for a water re-use holding pond," said Scott Sustacek, with Jordan Sands.
Second, who should regulate it, state or local governments?
"A town the size of Wabasha doesn't have the personel to monitor the impacts of frac sand businesses," said Wabasha City Council Member Lynn Schoen.
Activists are hoping for a statewide moratorium on new mines so that state organizations can study the impacts on silica sand to the environment, transportation, and health.
"This is really heavy industrial mining at its best and certainly impacts many more people than just the local people"
The mining companies say there are already plenty of regulations in place.
"We feel we have some of the best sand in the best place. It's a mining district, rail line, and everything is in place. Mining has been going on for 60 years," said Mike Caron, with Tiller Corporation.
Tuesday's meeting was just a hearing, giving people on both sides the chance to voice their opinions. The committee will now take all of the information they got today, and see if they need to come up with a bill to present to the House and Senate.


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The Vampire Diaries
The 5 Best Prom Looks From Movies and TV
April showers bring May flowers. They also bring the light at the end of the tunnel, known to us laymen as, the end of the school year. Before we can all jubilantly stand outside throwing our hats up in the air and blasting Twisted Sister, there are still some important milestones yet to come, and we ain't just talking finals. What could possibly be exciting that a calculus test? Prom. Across the globe, folks are getting ready for the big event. For some this means tackling final details (flowers, anyone?). For others there are still big decisions to be made — like what to wear!
Our favorite gaggle of Mystic Falls-ians are gearing up for Prom in The Vampire Diaries Season 4, Episode 19, "Pictures of You." Luckily for them, their prom adventures are already shot and in the can. But don't get too jealous. As history has proven, style has never been a hurdle for Elena, Caroline, Bonnie, or even Rebekah. But just because their prom will prove to be flawless fashion-wise, that doesn't mean they won't have hurdles to jump over... of the life-threatening kind. Still, at least they'll look good doing it! Here are five of our favorite Prom looks from movies and TV to get you psyched for prom.


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Park reopens after explosives scare
Authorities say a park in suburban Birmingham reopened after an explosives scare.
Shelby County sheriff's officials shut down Herdmont Park Sports Complex on Sunday morning after a caller reported a suspicious package.
Deputies decided the item needed to be examined by bomb experts and removed. Sheriff's officials say the package was discovered to be a hoax that didn't contain any explosives.
The park reopened after being searched by law officers.
The park is located of Alabama 119.


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by Eric Englund
July 9, 2007
Two hedge funds, managed by Bear Stearns, are on the verge of liquidation due to making highly leveraged bets on securities backed by subprime mortgages. Bear Stearns� woes have investors worried that any negative developments in the credit markets will also drag down the stock market � which has become quite volatile since the bad news, from Bear Stearns, surfaced. To be sure, the ripple effects of the subprime-mortgage implosion will continue to roil the credit and stock markets. But is the subprime-mortgage bust truly large enough to drag down Wall Street, and its precious Dow Jones Industrial Average, with it? If the recent performance of General Motors� stock is an indicator, the Working Group on Financial Markets (aka: the Plunge Protection Team) is answering this question with a resounding "yes."
As Karen De Coster and I asserted in our essay General Motors, Market Engineering, and "Confidence" Protection, the Working Group manipulates General Motors� stock in order to prop up the Dow Jones Industrial Average so as to maintain investor confidence in the stock market, Wall Street, and the economy in general. Indeed, based upon our assertion, General Motors� stock definitely has big shoes to fill. In light of GM�s stunning performance, during the exact period of Bear Stearns� hedge fund catastrophes, the "General" is strutting up and down Wall Street as if he is Sasquatch�with members of the Plunge Protection Team peering from behind the curtain in delight.
This past quarter � April 1, 2007 to June 30, 2007 � has been a barnburner for GM�s stock. Through this period, the Dow Jones Industrial Average was up by 8.5% while GM was up by nearly 23%; talk about market leadership. During the trading week of June 25th, when Wall Street was really feeling the heat of Bear Stearns� meltdown, General Motors� stock closed the week up by 6.6%. This isn't just leadership; no, the General is fearlessly spearheading the stock market�s charge upward. And it gets even better; for during this hard-charging week, GM�s stock hit a 52-week high which tallies up to nearly a 43% gain from its 52-week low. General Motors� stock, most certainly, closed this last quarter with a magnificent performance that served to steady a jittery stock market.
Interestingly enough, this magical week began with an upgrade from a Wall Street brokerage powerhouse. On June 25th, Goldman Sachs analyst Robert Barry put out a "buy" recommendation on General Motors citing his rather dull insight that "GM can make a compelling case to UAW members that material wage and benefit cuts are needed�And we suspect members and retirees are increasingly amenable to such cuts." Although this won't go down as an awe-inspiring recommendation, the reasoning is much less important than putting the prestige of Goldman Sachs� name behind General Motors� stock. And this is where, in my opinion, the heavy hand of the Plunge Protection Team has been exposed yet again.
So let's connect a few important dots here. For openers, the four key members of the Plunge Protection Team (which reports directly to the President of the United States) are the Secretary of the Treasury, the Chairman of the Federal Reserve, the Chairman of the Securities and Exchange Commission, and the Chairman of the Commodity Futures Trading Commission. Henry M. Paulson is the current Secretary of the Treasury. Before being sworn in as the Secretary of the Treasury last year, Mr. Paulson was the Chairman and Chief Executive Officer of � you guessed it � Goldman Sachs. Thus, Henry Paulson was once the aforementioned Robert Barry�s boss. In light of this, it is highly plausible that Goldman Sachs� buy recommendation � regarding GM stock � was a political favor to help the Plunge Protection Team do damage control on Wall Street.
Now, let's look a little deeper into the company whose common stock Robert Barry so uninspiringly recommended to American investors. Upon reviewing GM�s December 31, 2006 fiscal year-end audited financial statement, I certainly can see why Mr. Barry was so bland. To analyze General Motors� 12/31/06 FYE financial statement is to understand that this once great company is likely heading towards bankruptcy. Here are the gruesome details:
- GM�s "as stated" net worth is negative $5.4 billion
- By fully discounting intangible assets, which includes deferred tax assets, GM�s net worth is arguably negative $48.5 billion (refer to Note 13 of GM�s 12/31/06 financial statement)
- GM�s as stated working capital is negative $3.7 billion
- By fully discounting current deferred tax assets, GM�s working capital drops to negative $14 billion
- General Motors� total liabilities amount to a staggering $190.4 billion
- GM�s net loss, in 2006, was nearly $2 billion
In spite of the "General�s" ill financial health, Robert Barry proclaimed a 52-week target price of $42 per share. This target price was simply pulled out of thin air. Without earnings and without a tangible net worth, it is impossible to apply basic analytical tools � such as a price-to-earnings ratio and a price-to-book-value ratio � in order to derive a rational target price-per-share for General Motors� common stock. Since most "investors" are financially illiterate, it is easy for Wall Street analysts to get away with making such absurd proclamations.
This is not to say that Robert Barry didn't comprehend the gravity of GM�s financial condition. When Barry stated that "GM can make a compelling case to UAW members that material wage and benefit cuts are needed" he clearly understood the grim reality of General Motors� financial situation. In essence, Barry�s "buy" recommendation is based upon the bizarre logic that although GM�s acute financial weakness may be a "strength" when bargaining for concessions from the UAW, that investors should ignore this extreme financial fragility � but the UAW should not � so go out and purchase GM stock today. After all, this company just may survive if its negotiations, with the UAW, go exceedingly well. And what if the UAW doesn't give an inch? Heck, let's not spoil the convincing case (wink, wink, nod, nod) made by Goldman Sachs� star auto-industry analyst.
There is little doubt that Robert Barry "took one for the team"�the Plunge Protection Team that is. Typically, a "buy" recommendation is accompanied by exciting and positive developments regarding the company being analyzed. All Barry could muster was tortured logic intertwined into an insipid endorsement of a company teetering on failure. But the deed was done. Goldman Sachs� endorsement, of GM, gave the Plunge Protection Team the cover it desired to continue pushing GM�s share price higher; thereby providing market leadership investors yearn for when instability is afoot.
As I see it, the intense manipulation of GM�s stock indicates that the Plunge Protection Team is frightfully worried about the damage subprime mortgages will inflict upon Wall Street. In the end, it is quite ironic that General Motors� financial condition really isn't substantially different relative to the financially-strapped individuals who are defaulting on the very mortgages that toppled Bear Stearns� hedge funds.
© 2007 Eric Englund
Eric Englund has an MBA from Boise State University and lives in the state of Oregon. He is the publisher of The Hyperinflation Survival Guide by Dr. Gerald Swanson. You are invited to visit Hyperinflation.net.
Contact Information
Eric Englund
Author, Hyper Inflation Survival Guide


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Pic: Wiki
|An archaeological survey on the famous Scots isle of Iona – where St Columba landed 1450 years ago to spread Christianity in Scotland – has shown signs of ancient burials reports the Scotsman. This is the first geophysical investigation to be undertaken away from the core focus of the Columban monastic enclosure and the Benedictine Abbey. The surveys were carried out on National Trust for Scotland land on the island by Dr Sue Ovenden and Alastair Wilson of Rose Geophysical Consultants.
The pair examined two areas in the fields to the south of the village – one close to the current village hall and south of the Nunnery and the other at Martyr's Bay. The area close to the village hall seems to show features of recent or natural origin which will be excavated later this year. However, the more interesting result came from Martyr's Bay where there is a mound beside the road where skeletal remains were excavated in the 1960s.
Derek Alexander, the Trust's Head of Archaeology Derek, said:
The geophysical survey shows that on the landward side, this mound may have been revetted by stones and surrounded by a shallow ditch. This could be a sign of burials. It has always been suggested that there are numerous burial sites on Iona and there have been various finds over the years, the most famous of which is in the graveyard at Relig Odhrain to the south of the Abbey.
The burials that have been discovered so far are absolutely fascinating. For example, those unearthed by excavations at Martyr's Bay in the 1960s were quite unusual – there were some 40 skeletons packed into an area about 4m long by 2m wide. These appeared quite jumbled and many may have been reburied, especially as the carbon dating showed that one skeleton dating from the 13 – 15th century was below one dating from the 6 – 8th century.
It's possible that this mound has some connection to another graveyard that's marked on an old map, known as Clad Nan Druineach. We plan to investigate the area further in September, and hope that the findings will add more to what we already know about this fascinating island's cultural and spiritual story.
The findings are revealed as the island prepares for a special Service of Thanksgiving at Iona Abbey to mark the 1450th anniversary of Columba's arrival on Iona.
Read more about the story and the service on The Scotsman website.
You can also now download a Celtic Myth Podshow App from the iTunes store. This is the most convenient and reliable way to access the Celtic Myth Podshow on your iPhone or iPod Touch. You're always connected to the latest episode, and our App users have access to exclusive bonus content, just touch and play! To find out more visit the iTunes Store or our Description Page.
You can now also find an Android version of the App which works identically to the iPhone version. You can find it on Handster at http://www.handster.com/celtic_myth.html or by using the QR code opposite. It's also found on the Opera Marketplace in the US.
You can now also find the Windows 8 Phone App in the Windows 8 Phone Store.
If you come to the site and listen or listen from one of our players – have you considered subscribing? It's easy and you automatically get the episodes on your computer when they come out. If you're unsure about the whole RSS/Subscribing thing take a look at our Help page.


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text: The Winnipeg Jets have come to terms on a contract extension with head coach Claude Noel, general manager Kevin Cheveldayoff announced on Monday afternoon. The agreement will extend the term of Noel's contract for one-year. The financial terms of the deal have not been made public at the time of this writing. The coach was entering the final year of his contract in the 2013-14.


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Olympe Bhêly-Quenum was born in Ouidah in 1928. He initially studied in Dahomey (now Bénin) before moving to Accra, Ghana, where he learned English. After working for John Walden (Unilever), he saved enough money to go and study in France, arriving in Marseilles in 1948 and studied at the Collège Littré d'Avranches. He was a keen athlete, excelling, in particularly, at the high jump. He attended the Académie de Caen to which he received a scholarship. He also met his future wife, Maryvonne there. After obtaining a Master's degree he became a teacher, first in Normandy and then in Paris. When Dahomey became independent, President Hubert Maga asked him to train to be a diplomat. He attended the Institut des Hautes Etudes d'Outre-Mer. However, he decided to pursue a literary career, having written stories since meeting André Breton in 1949, who had encouraged him to write down a dream. He became editor of La vie africaine. The magazine closed down but, with his wife, he founded L'Afrique actuelle. However, for much of his career, he worked for UNESCO. As well as his novels, he has written extensive criticism. Note on his name. At his website, he spells his name Bhêly-Quenum. My copy of Un piège sans fin (Snares without End) (in French) spells it Bhêly-Quénum. Various websites spell it Bhély-Quénum or Bhély-Quenum. I am assuming that he knows how to spell his own name.
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HIV Drugs and the HIV Lifecycle
March 2012
Table of Contents
The Basics
HIV drugs cannot cure HIV but they can help you stay healthy by preventing the virus from reproducing (making copies of itself). When HIV cannot reproduce, it cannot infect new cells in your body and your . viral load remains low.
HIV must go through a number of different steps in order to make copies of itself. This is called the HIV lifecycle. All HIV drugs work by interrupting a step in HIV's lifecycle, thereby stopping HIV "in its tracks."
The HIV Lifecycle
Once HIV is in the body, it targets and infects a certain type of white blood cell called a CD4 cell. HIV then takes over or "hijacks" these cells and turns them into factories that produce thousands of copies of the virus. The steps HIV goes through to complete this process are as follows:
Walgreens HIV Centers of Excellence Pharmacies Now Top 500 Nationwide in Areas Most Impacted by HIV/AIDS
This article was provided by The Well Project. Visit The Well Project's Web site to learn more about their resources and initiatives for women living with HIV. The Well Project shares its content with TheBody.com to ensure all people have access to the highest quality treatment information available. The Well Project receives no advertising revenue from TheBody.com or the advertisers on this site. No advertiser on this site has any editorial input into The Well Project's content.
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July 31, 2015
WASHINGTON (AP) Sen. John McCain says the cause of rebels fighting Syria's President Bashar Assad has been obscured in the rapid-fire military and diplomatic events following a chemical weapons attack near Damascus.
McCain says, quote, "I feel very badly for my friends in the Free Syrian Army today."
The Arizona Republican tells MSNBC he's not against negotiating to defuse the chemical weapons issue. But McCain also argues, "There's nothing that will drive Syrians more into the hands of extremists than to feel they have been abandoned by the West."
One of the persistent questions about U.S. policy in war-ravaged Syria is to what extent the terrorist network al-Qaida is involved in the efforts to end Assad's rule. McCain said President Barack Obama should have acted more forcefully against Assad many months ago.
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An ink jet printhead and process for manufacturing same wherein an opening in an orifice plate of the printhead is precisely aligned with a transducer element on a thin film substrate member of the printhead. A barrier layer having an opening therein is aligned with the transducer element and is located on the thin film substrate member adjacent to a metal seed layer. A metal orifice layer is plated on the metal seed layer and over the barrier layer and extends into the opening therein to form a convergent orifice opening. This opening is aligned to both the opening in the barrier layer and the transducer element on the thin film substrate member. Since the transducer element and metal orifice plate layer are both precisely aligned to the opening in the barrier layer, the transducer element and the metal orifice layer are said to be "self-aligning".
1. A process for accurately aligning an orifice opening in an orifice plate of an ink jet printhead with a transducer element on a thin film substrate member of said printhead, which includes the steps of:
a. providing a transducer element within a thin film substrate,
b. providing a metal seed layer having an opening therein on said thin film substrate,
c. providing a barrier layer on said thin film substrate and adjacent said opening in said seed layer,
d. providing an opening in said barrier layer and aligning said opening in said barrier layer with said transducer element in said thin film substrate, and
e. plating a metal orifice layer on said metal seed layer and over said barrier layer to form an orifice opening extending within said opening in said barrier layer and aligned thereto, whereby said orifice opening is aligned to both said opening in said barrier layer and to said transducer element in said thin film substrate.
2. The process defined in claim 1 wherein the plating of said metal orifice layer includes plating a first orifice plate section over a portion of said barrier layer and then plating a second orifice plate section as an extension of said first orifice plate section to form a convergent nozzle opening within said opening in said barrier layer and aligned with said transducer element.
3. An ink jet printhead characterized by the precise alignment of an orifice plate disposed on top of a thin film substrate and comprising:
a. a transducer element located within said substrate and having electrical conductors connected thereto for providing energizing pulses to said transducer element during an ink jet printing operation,
b. a seed layer having an opening therein disposed on said substrate,
c. a barrier layer disposed on said thin film substrate and located adjacent to said opening in said seed layer, said barrier layer having an opening therein aligned with said transducer element, and
d. a metal orifice layer plated up from said seed layer and over said barrier layer and having an orifice opening therein located within and aligned to said opening in said barrier layer, whereby said opening in said orifice plate is also aligned to said transducer element in said thin film substrate.
This is a division of application Ser. No. 07/125,433, filed 11/25/87 U.S. Pat. No. 4,894,664.
This application is a continuation-in-part of my earlier parent application Ser. No. 856,740, filed Apr. 28, 1986.
A prior-art thermal ink jet printhead 2 is shown in FIG. 1. The advancement of thermal ink jet (TIJ) technology stumbles upon an assembly problem: detachment of the nozzle plate 1. Presently, each nozzle plate 1 is individually attached to the resistor structure 3 as shown in FIG. 2A. This costly procedure is problem-prone. For example, this procedure often misaligns the nozzle plate 1. FIG. 2A, a simplified representation of the prior art, omits many of the details. The differences in thermal expansion coefficients among different components of the TIJ printhead 2 tend to debond the nozzle plate 1 during the curing process of the glue. This adhesion problem limits the number of nozzles in the TIJ printhead 2.
The ink refilling rate of prior-art TIJ printhead 2 presents another problem. It limits the printing speed. In prior-art TIJ printheads 2 shown in FIG. 2B, ink reaches the nozzle 6 after traveling through high friction channels 7 which restrict the ink flow.
The invention described in U.S. Pat. No. 4,438,191, Monolithic Ink Jet Print Head, incorporated herein by reference, proposes a monolithic ink jet printhead that would solve some of the problems listed above. However, the fabrication of this device presents additional problems: formation of ink holes, removal of dry film residue from the firing chambers and other locations, proper alignment of the nozzle, and various manufacturing problems. Also, the nozzles of the monolithic printhead do not diverge.
The present invention, a monolithic thermal ink jet printhead with integrated nozzle and ink well and a process for making it, solves the nozzle attachment and ink flow problems of prior-art printheads mentioned above. Also, the present invention reduces manufacturing costs and improves reliability. The reduced manufacturing costs are partially achieved through an automated manufacturing procedure. The increased reliability is partially achieved through longer resistor life and smoother ink flow in the printhead. Without these improvements, page-width TIJ print arrays would not be possible.
Further advantages of the present invention include the automatically-aligned nozzle 19, shown in FIG. 3. Prior-art processes misalign the nozzle plate 1 shown in FIG. 1. This misalignment causes dot spread and slanted printing. The new monolithic TIJ printhead 20 reduces resistor failure. In prior-art TIJ printheads shown in FIG. 1, the collapsing bubble and refilling ink impact the resistor surface. The cavitation force eventually destroys the resistor. In the new monolithic TIJ printhead 20 shown in FIG. 3, the collapsing bubble collides with the refilling ink. The ink absorbs most of the cavitation forces. The cantilever beams 12, upon which the heating element, such as a resistor, is built, absorb the remaining cavitation force. The cantilever beams, constructed from ductile nickel, float in a reservoir of ink. The mechanical forces on resistors will be buffered by the flexibility of the cantilever beams as well as the ink itself.
Also, in the present invention printing speed is not limited by the ink refilling rate. The ink well 11 is directly connected to the heating elements 15 as shown in FIG. 3. This direct connection reduces resistance to ink flow. Thus, printing speed is not limited by the ink refilling rate.
Accordingly, a novel feature of the present invention is the provision of a thermal ink jet printhead of the type described wherein an orifice plate is electroplated up and over a barrier layer having an opening therein which was previously aligned with a thermal ink jet heater resistor. Since both the orifice plate and the thermal ink jet heater resistor are both aligned to an opening in the barrier layer, they are aligned to each other or are "self-aligning". A convergent nozzle opening in the orifice plate is precisely aligned with a center line through the heater resistor transducer element. In a preferred embodiment of the invention, the plating of the metal orifice layer includes plating a first orifice plate section over a portion of the barrier layer and then plating a second orifice section as an extension of the first orifice section to form the above described convergent nozzle opening aligned with the heater resistor transducer element.
FIG. 1 shows a prior-art thermal ink jet printhead.
FIG. 2A shows a cross section of a prior-art nozzle.
FIG. 2B shows a top view of a prior-art nozzle, the cut A--A corresponds to the cross section of FIG. 2A.
FIG. 3 shows a cross-section of the preferred embodiment of the invention with cantilever beams.
FIG. 4 shows a top view of the preferred embodiment of the invention with the nozzle removed; the cut A--A corresponds to the cross-section of FIG. 3.
FIGS. 5A-5C show steps in preparing the substrate for masking.
FIGS. 6A-6C show the formation of the cantilever beams and the well.
FIG. 7A shows the formation of the resistor layer and a protective layer.
FIG. 7B shows the formation of the conducting layer for the nozzle and the donut-shaped frame for the nozzle.
FIGS. 8A, 8B, and 8C show the steps taken to construct the nozzle shown in FIG. 3.
FIG. 9 shows an alternate embodiment of the invention without cantilever beams.
FIG. 10 shows a top view of the alternate embodiment shown in FIG. 9.
FIG. 11 is a cut-away isometric view of a thermal ink jet printhead showing only a single cantilevered heater resistor for sake of brevity and cut-away at the center line of the heater resistor. FIG. 11 is taken along lines 11--11 of FIG. 12.
FIG. 12 is a plan view taken along lines 12--12 of FIG. 11.
FIG. 3 shows a cross-section of the preferred embodiment of the invention, a monolithic thermal ink jet printhead with integrated nozzle 19 and ink well 11. FIG. 4 shows a top view of the monolithic printhead 20. Inside the substrate 10 a well 11 resides to hold ink. The heating element, a resistor layer 15, evaporates the ink. The ink (water vapor, glycol, and ink pigment particles) migrates to the nozzle area 17. The compound bore nozzle 19 directs the gaseous ink as it is expelled from the nozzle area 17 by pressure from the accumulated ink.
A thermal barrier layer 21 prevents heat from flowing to the nickel cantilever beams 12 and nickel substrate 40. With this arrangement, heat from the resistive layer 15 heats the ink and is not wasted on the printhead 20. A patterned conducting layer 23 shorts out the resistive layer 15 except on the cantilever beams 12. A protective layer 25 prevents electrical shorts during the nickel plating process to form the nozzle 19. The protective layer 25 also protects layers from chemical and mechanical wear. A conducting layer 27 is deposited during the manufacturing process to provide a surface upon which the nozzle 19 can be constructed.
The process to manufacture monolithic thermal ink jet printheads 20 involves several steps. On a substrate 10 of glass or silicon shown in FIG. 5A, a conducting layer 30 approximately 1000 Å is deposited using a sputter deposition technique. By conducting electricity through the conducting layer 30, a surface is formed to which nickel plating can be attached. Next, a dry film mask 32 is laminated on the conducting layer 30 as shown in FIG. 5B. This mask 32, having a diameter of 2 to 3 mils, defines the location of the cantilever beams 12 in FIG. 3 as well as 13 in FIG. 9. FIG. 5C shows the various shapes a mask 32 can have. Mask 38 corresponds to the printhead 20 shown in FIGS. 3 and 4. Mask 34 corresponds to printhead 60 shown in FIGS. 9 and 10. The mask 39 corresponds to printhead shown in FIGS. 11 and 12.
Next, an electroplating process deposits a nickel layer 40 from 1 to 1.5 mils thick onto the exposed substrate 10. Thus, cantilever beams 12 are formed. After completion of the plating, removal of the dry film mask 38 exposes the cantilever beams 12 shown in FIG. 6B. The well 11 is formed through a multi-step process. First, a sputtering process deposits a protective metal layer 42. This layer is made of gold and has a thickness of 1000 Å. Next, a mask 44 defines the well 11. Then, a wet chemical etching process, such as KOH for silicon or HF for glass, forms the well 11. When the protective layer 42 and the mask layer 44 are removed, the device appears as shown in FIG. 6C. The conductive layer at the bottom of the well 11 is then removed using a selected metal etchant.
Next, a thermal insulating layer 21, made of LPCVD SiO2 or another dielectric, is deposited. It is deposited to a thickness of 1.5 microns on the inside of the well 11, on top of the plated nickel layer 40, and around the cantilever beams 12 as shown in FIGS. 3 and 7A. The thermal insulation layer 21 encourages the efficient operation of the resistor layer 15. On top of the thermal insulating layer 21, a resistive layer 15 made of material such as tantalum-aluminum is deposited to a thickness of 1000 Å to 5000 Å as shown in FIGS. 3 and 7A. Next, a conducting layer 23 made of gold or aluminum to a thickness of 5000 Å is selectively patterned on resistive layer 15 to short out portions of the resistive layer 15. The conducting layer 23 is not present on the cantilever beam 12 so that the resistive layer 15 is operative there. On top of the conducting layer 23, a protective layer 25 made of silicon carbide, SiC, silicon nitride, Si3 N4, or other dielectric material is deposited using a low pressure chemical vapor deposition (LPCVD) process. This layer protects the device from chemical and mechanical wear.
A conducting layer 27, 1000 to 5000 Å thick, is deposited on the protective layer 25. It is formed by sputtering. The conducting layer 27 provides a surface upon which the nozzle 19 can be formed with an electroplating process. Next, portions of the conducting layer 27 are etched away through a wet-etching process as shown in FIG. 7B, so that the only conducting layer 27 remaining is located where the nozzle will be constructed.
Next, donut-shaped dry film blocks 52 are laminated onto the conducting layer 27. These blocks 52 form a frame for the construction of the nozzle 19. In the preferred embodiment of the invention, the nozzle 19 is constructed in a two-step plating process. The results of the first step are shown in FIG. 8A. The base of nozzle 19 is formed by electroplating nickel onto the conducting layer 27 to a thickness of 1.5 mil to 2.0 mil, which equals the height of the nozzle 19. Next, a glass slab or any other flat dielectric material 56 is pressed on the nozzle 19 as shown in FIG. 8B. This slab 56 acts as a nozzle 19 mold for the second part of the nickel plating process. FIG. 8C, the electroplating process is continued to form the nozzle 19. Now that the nozzle 19 is completed, the slab 56 is removed. The resulting product is the printhead 20 shown in FIG. 3. Other methods can be used to form the nozzle 19. For example, the nozzle 19 could be constructed through a one-step plating process without the use of the slab 56.
FIG. 9 shows an alternate embodiment of the printhead 20. A nozzle 19 having this shape is called a compound-bore nozzle 19. It controls the stream of ink ejected from the nozzle 19. The ink stream ejected from a compound-bore nozzle has a narrow diameter and minimum spread. The cantilever beams 13 protrude inward and the heating element 15 rests on top of the cantilever beam 13. This embodiment of the printhead 20 would be formed in the same way as the printhead 20 shown in FIG. 3. The primary difference in the process would be in the type of mask 32 used when layer 40 is placed onto substrate 10. Instead of mask 38 for the cantilever beams 12, a mask similar to mask 34 is used.
Referring now to FIG. 11, this view is cut-away at the center line of the cantilevered heater resistor 60 which is disposed on top of an insulator material 62. The insulator material 62 is shown as only a single layer in FIG. 11 for sake of brevity, but it will be understood that this insulating material 62 may be formed of multiple insulating and protective layers inthe same manner as described above with reference to earlier figures. The insulating material 62 is formed around the cantilever beam 64 which extends from one side to the other of the ink reservoir walls 66. These walls 66 partially define the ink flow paths on each side of the cantilever beam 64 and these paths receive ink from the lower ink reservoir beneath the heater resistor 60 and defined by the slanted walls of insulating material 68 which cover the previously etched substrate 70. This etching step has been previously described with respect to the fabrication of the structures in FIGS. 3 and 9.
The substrate 70 of either glass or silicon, for example, is initially covered with a flexible support layer 72 of nickel plating which of course is the same material that forms the cantilever beam 64. The heater resistor 60 on the top of the beam 64 is electrically interconnected to a conductive trace or strip 74 which is shown only at one side of the resistor 60, but will also exist at the other side of the resistor 60 and not shown in FIG. 11.
A seed layer is patterned as indicated at 76 to form the necessary nickel seed growth material for the orifice plate to be formed, and a dry polymer film is patterned in a manner previously described to leave an annular ring 78 encircling the cantilevered resistor 60 and its associated ink flow port surrounding the resistor. This annular ring 78 serves to define the upper ink reservoir area over the heater resistor 60. This annular ring 78 may, for example, be fabricated of a polymer material such as RISTON or VACREL available from the DuPont Company, and is used to define the convergent orifice geometry for the upper nickel nozzle plate 80. The nozzle plate 80 may be formed in a two step process as described above to provide the converging orifice surfaces 82 which terminate at the output orifice opening 84 on the outer surface of the orifice plate 80. The preference for this convergent orifice geometry is described in more detail in U.S. Pat. No. 4,694,308 issued to C. S. Chan et al, assigned to the present assignee and incorporated herein by reference.
Thus, from the cut-away isometric view in FIG. 11 and its associated plan view of FIG. 12, it is clearly seen that not only does this printhead structure provide for an improved ink flow rate to the resistive heater 60, but it simultaneously provides for the cooling of the heater resistor 60 and it simultaneously minimizes the cavitation wear received by the heater resistor 60. This is partially the result of the flexible nature of the cantilever beam 64 which allows the surrounding ink to receive and absorb cavitational forces resulting from ink ejection. During the flexing of this cantilever beam 64 during an ink jet printing operation, cavitational forces transmitted to the heater resistor 60 from the output orifice 82, 84 are retransmitted to the surrounding ink where the resistor 60 is simultaneously cooled. And, the cooling of the heater resistor 60 is a very significant feature of present inventio and its ability to maximize resistor and orifice packing density within the ink jet printhead.
Finally, using the polymer masking and nickel electroforming techniques previously described to define the geometry of the orifice plate 80, the center line of the orifice opening 84 may be either precisely aligned with respect to the resistor 60, or in some structures it may be desired to provide a predetermined offset between the center line of the orifice 84 and the mid point of the heater resistor 60.
In the preferred embodiment of the invention, the printhead ejects ink which contains water, glycol, and pigment particles. However, it can be used to eject other substances.
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Paying Your Student Account
- How to Pay
- Fee Payment Due Dates
- Interest Charges
- Financial Blocks
- Returned Payments
Your Student Account Online Statement reflects all charges assessed to your account. You can pay your student account through your bank, credit union or caisse populaire using telephone or online banking.
Although there is not a specific charge on your account for the undergraduate registration deposit (which is part of your tuition fees), housing deposit, or graduate confirmation deposit these can be paid using telephone or on-line banking as well.
- Contact your financial institution (bank, credit union or caisse populaire) in order to set up your bank account(s) for telephone or online banking. The company name/payee is York University.
- Use your York student number as the account number.
- If you are an international student you may pay for course/program fees, residence, health care and UHIP charges appearing on your student account using the bank-to-bank transfer service.
- When you pay through telephone or online banking through a major Canadian bank (TD Canada Trust, RBC Royal Bank, Scotiabank, CIBC or BMO Bank of Montreal), it may take up to four business days for your payment to be transferred to your York student account. Processing times through other banking institutions may be longer.
- Please ensure you allow enough time between your payment and the due date for funds to be posted to your account.
You can check your Student Account Online Statement to view recent transactions. Allow a few days for your payment to be applied to your account.
NEW! You can now convert Aeroplan® Miles to tuition funds through HigherEdPoints.com. 35,000 Aeroplan® Miles can be converted into $250 worth of credits toward your fees. For more information, including how your family members can donate their points, and to set up an account, please visit HigherEdPoints.com.
Are you paying your course/program fees with RESP money? Visit the Request a Letter page for detailed information on how to download a Verification of Enrolment and Registration Letter for submission to your RESP provider with the RESP forms you are required. This form may also be used for other purposes if confirmation of total credits completed and in progress is required.
New for 2015-2016: Tuition fees for full-year courses will be charged over two terms: fifty percent (50%) of full-year course fees will be due in September, and the remaining fifty percent (50%) will be due in January. View an explanation of understanding your monthly statement to estimate your September and January payment obligations.
Statements are run around the 18th of each month and capture course/program enrolment activities, residence fees, meal plan and telecommunication charges as well as payments made since the last statement was run. Each statement calculates a minimum payment due that month and indicates the due date. If there are overdue amounts, an interest charge is also calculated at that time.
Please note that statements are not routinely mailed to students. Review the "minimum payment due this month" on your Student Account Online Statement around the 18th of each month to determine if there is an amount owing.
Normally payments are due as follows:
- the undergraduate registration deposit is due soon after enroling in courses;
- fees for fall and full year undergraduate course enrolments are due September 10;
- fees for program-based undergraduate programs (e.g. BDes) are due September 10;
- half the fees for residence charges and meal plans are due September 10;
- half the fees for residence charges and meal plans are due January 10;
- fees for winter undergraduate course enrolments are due January 10;
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- health plan fees are usually charged in September through November and are due the 10th of the following month.
Osgoode students in their first year of study have different due dates for fee payments. Please refer to information provided by Osgoode.
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Any activity that takes place after a statement is generated will be reflected on the following month's statement. Therefore, if you drop a course after August 18, it will not be reflected on your August statement; it will appear on your September statement and will be part of your amount due on October 10.
Payments on your student account are due on the 10th of each month. If you do not pay the "minimum payment due this month" to the University by this date, you will be subject to interest charges of one per cent monthly on the amount owing from your last statement. The annual interest rate is 12.7 per cent. Interest charges are not assessed on fees for courses that begin in a future academic session or on transactions that appear for the first time on your statement.
Fall/Winter students who have applied for OSAP by York's recommended deadline of June 30, but have not yet received their funds, will not be charged interest on overdue amounts for the months of September, January and/or May.
Students who cannot pay the full amount of their fees by the due date are expected to make regular monthly payments to reduce their outstanding balance as quickly as possible. Students having difficulty meeting their financial obligations should contact Registrarial Services in the Bennett Centre for Student Services as quickly as possible; Glendon students should contact Glendon Student Financial Services.
If you have an overdue balance of more than $75 for undergraduate students or $1,000 for graduate students on your student account at any point after the dates listed below, you will be blocked from adding new courses, changing sections or exchanging one course for another through the online Registration and Enrolment Module (REM); however, you will still be able to drop courses. You will also be blocked from requesting a transcript, and will not be able to receive your diploma upon graduating..
- November 1 - you will be blocked from adding or changing courses in the current session
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In order to remove the block, you must make your payment through telephone or online banking to reduce your account balance to less than $75 for undergraduate students or less than $1,000 for graduate students. Your block will be automatically lifted the day after your payment appears on your Student Account.
Please note: statements are not routinely mailed out to students; to find out how much you owe, view your statement or recent transactions, check your Student Account Online Statements.
If a bank returns your payment for any reason, you are subject to the following penalties:
- a $50 non-refundable administrative charge;
- de-enrolment, if the undergraduate registration deposit is returned;
- de-registration, if any subsequent payments are reversed by the bank.


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Watch Episode 6 of the Follow Me Series: Msgr. Brian Brownsey
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Bipin Chandra Pal was an orator, writer, teacher, journalist and most importantly, popular extremist freedom fighter of India. His logical thinking recognized the advantages that the British rule offered to his country but he was in favor of having a federal India. He practiced his radical beliefs in his public as well as private life. He expressed his disapproval of the foreign rule through extreme actions. He did not mince his words in condemning Gandhi's way of leading the national struggle.
Childhood Days
On November 7th 1858 he was born inHabibganj (Assam). This place is a part of Bangladesh now. He belonged to a wealthy family. His father was a landlord, who exercised significant clout in the neighboring areas. In contrast to the norm of sending children to pathshalas, his father taught him at home. He learnt Persian from a maulavi. He received formal education in Church Mission Society College where later, he became a teacher.
He did not shy away from practicing his progressive views. In order to show his support for widow remarriage, which at the time was a very sensitive issue, he married a widow, Nrityakali Devi in 1881. After her untimely death, he remarried. This time too, the bride was a Brahmin widow, Birajmohini Devi.
Meeting With Eminent Personalities
While he was a student, he got the opportunity of meeting several distinct personalities. These people helped him formulate his radical viewpoints. Anandmohan Bose, Aghoreenath Chatterjee, Dr. Sundarimohan Das and Dwarkanath Ganguli acted as his associates while Keshabchandra Sen led him towards the Brahmo Samaj principles.
Role in Inculcating the Feeling of Nationalism
Bipin Chandra Pal was amongst the first few Indians, who saw through the British policy of Divide and Rule. He joined the Indian National Congress in 1886. In 1905, the British Government divided Bengal. The ostensible purpose was easy administration of the region, as it was too big to be managed under a single one. However, Bipin Chandra Pal along with Lala Lajpat Rai and Bal Gangadhar Tilak (together popularly known as Lal Bal Pal) severely criticized this act of the Government. They knew that the British Raj wanted to extinguish the feeling of nationalism in the people of Bengal. That is why it divided the region to break their unity based on their religions.
Radical Views Clashing with Gandhi's Non-Violent Methods
Bipin Chandra Pal took drastic measures to revolt against the British. He openly boycotted foreign goods by burning them and wholeheartedly, took part in the lockouts in government factories. Along with other national leaders, he launched the Swadeshi Movement. Its motto was to encourage Indians to use products made of domestic produce. He was also a strong supporter of education, as it would have helped remove social evils.
He was a well-known personality of the Indian National Movement when M.K Gandhi joined it. Gandhi's non-violent ways of nationalism did not appeal to him at all and he criticized him on many occasions, once openly in 1921.
The last six years of his life were spent in poverty and utter loneliness. Actually, his closeness to the Khilafat Movement alienated him from the Congress. He passed away in 1932.


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In the last Beauty Bytes post I mentioned my growing obsession with rose scented beauty products. I'm sure it goes back to the days of running around my Grandma's garden, gathering pocketfuls of rose petals then crushing them in water to make my own perfume. Sadly the resulting potion never quite hit the spot but the process itself still holds magical memories.
I was recently sent the new Pure DKNY Rose eau de parfum and given my love of this particular scent, it's a joy to share my thoughts on this fragrance.
Often a spritz of perfume is one of those last minute, hurried additions before hurrying out the door in the morning. For me, Pure DKNY Rose is a prompt to stop, close my eyes and inhale.
The initial hit of rose is beautifully sweet but by time you reach the end of a deep breath in, there's an underlying, modern sultriness to it that I love. After my childhood efforts at playing perfumer, I was intrigued to read how I've ended up with this perfect rose scent.


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Madeline Magee
steven ashford
austin Hampton
Josholynn Hunter
Through this experience we want to explore different careers. Also, as a team we want to learn from each other and learn about one another. From the people we interview we want to learn how they got where they are today. Therefore, we want to know how they got started and how they decided on their career. Most importantly the advice that they will give us will hopefully inspire us to find the career for each one of us in the group.
Career Planning
Caragh Boyles
Home Base:
Mississippi State University Career Center
All Rights Reserved
Last assignment
I enjoyed interviewing different people from different jobs. I learned that you should do something you love and not listen to anyone tell you what you should do. i learned from interviewing that life can be rough with out a degree so we should stay in school and get an education so we can survive.
Written on November 29, 2010 at 10:05am
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text: hey im new to this forum but im not new to the car. i thought i would list this car everywhere to get maximum exposure. i got a mustang locally for a reasonable price with title issues so im parting it out. let me know what your looking for ill have great prices and can ship or arrange local pick up. car is a 1991 5.0 gt automatic. blue hatchback 16 inch pony wheels with good tires all around black and grey inside seats are decent but not perfect all around many good parts email me and i can reply with prices and pictures of whatever your interested in [email protected]


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Games of the II Olympiad
The Games of 1900 were held in Paris as part of the Exposition Universelle Internationale – the Paris World's Fair. The exposition organizers spread the events over five months and de-emphasized their Olympic status. Women made their first appearance in the modern Games in golf, tennis and croquet.
In 1900, no official Canadian team was sent but George Orton, a Canadian from Ontario studying in the United States, won two medals competing on his own. He won gold in the 3,000m steeplechase and bronze in the 400m hurdles event. Orton also finished fifth in the 4,000m steeplechase. He is regarded by the Canadian Olympic Committee as the first Canadian Olympic medallist.


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Richard III
Performance Network
April 24 - June 1, 2014
Posted: April 16, 2014 at 8:53 a.m.
ANN ARBOR - From April 24 through June 1, William Shakespeare's famous history "Richard III" gets an innovative treatment in this boldly re-imagined tale of power, treachery, seduction and fate. Directed by Julia Glander, this revolutionary take on the age-old classic explores the themes and fate of gender, power and government set in the distant yet ominous future. This is an exciting first-time collaboration between student actors and faculty of Eastern Michigan University Theatre and the artists of Performance Network Theatre.
In this gender-fluid rendition of "Richard III," associate artistic director Carla Milarch stars as Richard III, the ruthless and conniving Plantagenet, whose ascent to power is littered with corpses. By casting this show in a gender blind style, Performance Network's production of "Richard III" seeks to examine the relationship between gender, identity and power. Milarch's rendition of Richard III is a transgender man who was born in a female body. Other examples of gender-fluid casting include John Seibert as Queen Margaret and Alysia Kolascz as Hastings. Other characters were cast that matched the gender of the actors, including Terry Heck as the Duchess of York, and Logan Ricket as Catesby.
"The quest for power (the crown) really felt like a means of survival - a perfect setting, actually, for a villain to take advantage of a disheartened people. Make our villain a female who openly identifies as a male, and it opens up possibilities for a time period in which gender fluidity comes to the forefront. I am particularly excited to have Carla Milarch bring a new, outrageous, audacious, and humorous re-imagining to Shakespeare's 'Richard III,'" said Glander.
Performance Network's production of "Richard III" may intrigue students, intellectuals, theater lovers and countless others with this dystopian interpretation of a Shakespearean classic. Patrons will be immersed into the future by set, props, and projections design by Monika Essen, lighting design by Daniel C. Walker, costume design by Katherine Nelson, and sound design by Will Myers.
"Richard III" runs Thursday through Sunday, April 24 - June 1 at Performance Network Theatre. Previews begin Thursday, April 24; opening night is Friday, May 2.
Regular tickets are $27 - $46 with discounts for students, seniors, children under the age of 16, and military. Tickets can be purchased online at www.performancenetwork.org or by calling the box office at 734-663-0681, or at the theater at 120 East Huron in Downtown Ann Arbor.
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Quiz: Do you know which TV bosses gave these pieces of career advice?
Name the famous TV bosses that said these quotes — and get some career advice along the way!
Everything you need to launch the search, rock the interview, land the offer, negotiate pay, and get ahead once you've got the job.


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A Texas Hill Country mom and pop award winner! Low Motel Rates, Great Hotel Value. Enjoy friendly, family-style service, clean, comfy rooms, wireless internet, Direct TV, and more. Interstate 10, Exit 456, Owned by family of U.S. Vets.
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Find great deals on quality Junction, Texas hotels & resorts, or indulge at one of our luxury resorts. Take advantage of the many amenities that can be included with your stay such as in-room internet access, wifi, room service, fitness center, pool, hot tub, steam room, and shuttle services to and from the airport. Browse our Junction, Texas hotels and resorts and plan your Junction, Texas vacation today!


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OTC Guide
Community Pharmacist
Hospital Pharmacist
Student Pharmacist
Pharmacy Technician
Specialty Pharmacist
Resource Centers
Acid Reflux
Acute Coronary Syndrome
Atrial Fibrillation
Bipolar Disorder
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Cough and Cold
Heart Failure
Hepatitis C
Infectious Disease
Pain Management
Pharmacy Management
Type 2 Diabetes
Vitamins and Supplements
Women's Health
Continuing Education
New Specialty Drugs
Stacey Ness, PharmD, RPh, CSP, MSCS, AAHIVP
Published Online:
Thursday, March 13, 2014
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In 2013, many new medications and new indications were approved.
The year 2013 marked the approval of many new specialty medications, with drug debuts and new indications in areas including oncology, hepatitis C, HIV, multiple sclerosis, and inflammatory disease. This article provides a selection of specialty pharmacy– related FDA approvals and expanded indications for 2013.
(imatinib mesylate; Novartis) received an expanded indication on January 25, 2013, to treat children newly diagnosed with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia in combination with chemotherapy. A kinase inhibitor initially approved in 2001, Gleevec is approved to treat many oncologic conditions.
A new indication was granted to
(lenalidomide; Celgene) on June 5, 2013, when the FDA approved its use in mantle cell lymphoma (MCL) in patients whose disease has relapsed or progressed after 2 prior therapies, 1 of which included bortezomib. It is given orally once daily for 21 days out of a 28-day cycle. Revlimid is only available through a restricted distribution program in conjunction with a risk evaluation and mitigation strategy (REMS) due to potential for embryo-fetal risk.
(obinutuzumab; Genentech) was approved on November 1, 2013, for use in combination with chlorambucil for the treatment of patients with previously untreated chronic lymphocytic leukemia. Gazyva is the first CD20-directed cytolytic antibody to be approved in the United States and is administered as an intravenous infusion.
On November 13, 2013,
(ibrutinib; Pharmacyclics) was approved to treat patients with MCL who have received at least 1 prior therapy. Imbruvica is an inhibitor of Bruton's tyrosine kinase and is dosed as 560 mg (four 140-mg capsules) taken orally once daily with a glass of water.
(efavirenz; Bristol-Myers Squibb) was granted an expanded patient population on May 3, 2013, when the FDA approved a supplemental new drug application that included dosing recommendations for HIV-1–infected pediatric patients aged 3 months to 3 years and weighing at least 3.5 kilograms. As part of the approval for this pediatric population, a once-daily option is available that includes capsule sprinkle administration for those who cannot swallow capsules or tablets. Sustiva was previously approved in the United States in 1998 to treat HIV-1–infected adults and children 3 years or older and weighing at least 10 kg.
On August 12, 2013, the FDA approved
(dolutegravir; GlaxoSmithKline), a new antiretroviral agent to treat HIV-1 infection. Tivicay is an integrase strand transfer inhibitor (INSTI) which interferes with an enzyme necessary for HIV replication and must be taken daily in combination with other antiretroviral drugs. The FDA approved Tivicay for treatment-naïve HIV-infected adults and treatment-experienced HIV-infected adults including those previously treated with other INSTIs, as well as for a pediatric indication in treatment-naïve or treatment-experienced children 12 years and older weighing at least 40 kg who have not had a previous exposure to INSTIs. Dosing is dependent on patient-specific parameters and begins at 50 mg once daily with or without food.
(simeprevir; Janssen) was approved as a new option to treat hepatitis C virus (HCV) on November 22, 2013. Olysio is an HCV NS3/4A protease inhibitor indicated for the treatment of chronic hepatitis C infection as a component of a combination antiviral treatment regimen. Olysio is not to be used as monotherapy, and its efficacy has been established in combination with peginterferon alfa and ribavirin in HCV genotype 1–infected patients. Screening patients with HCV genotype 1a infection for the presence of virus with the NS3 Q80K polymorphism at baseline is strongly recommended, and alternative therapy should be considered for patients infected with HCV genotype 1a containing the Q80K polymorphism. Olysio is dosed as one 150-mg capsule taken once daily with food and should be administered with both peginterferon alfa and ribavirin. The recommended treatment duration of Olysio with peginterferon alfa and ribavirin is 12 weeks, followed by either 12 or 36 additional weeks of peginterferon alfa and ribavirin, depending on prior response status.
On December 6, 2013, the FDA approved
(sofosbuvir; Gilead) as another new option to treat HCV. Sovaldi is an HCV nucleotide analogue NS5B polymerase inhibitor indicated for the treatment of chronic HCV infection as a component of a combination antiviral treatment regimen. Sovaldi has demonstrated efficacy in patients with HCV genotype 1, 2, 3, or 4 infection and is given as one 400-mg tablet once daily with or without food. Sovaldi should be used in combination with ribavirin or in combination with pegylated interferon plus ribavirin. The recommended combination and duration of therapy is dependent on the genotype of the virus and the prescribing information should be consulted for specific details.
Stacey Ness, PharmD, RPh, CSP, MSCS, AAHIVP, is a multiple sclerosis–certified specialist, credentialed HIV pharmacist, and certified specialty pharmacist, and is the director of specialty clinical services at Managed Health Care Associates, Inc, a health care services organization in Florham Park, New Jersey. Dr. Ness is an associate editor for
Specialty Pharmacy Times.
FDA approves Gleevec for children with acute lymphoblastic leukemia [press release]. FDA website. www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm336868.htm. Published January 25, 2013. Accessed January 7, 2014.
US Food and Drug Administration approves Revlimid (lenalidomide) for the treatment of patients with relapsed or refractory mantle cell lymphoma. Celgene; June 5, 2013. Accessed January 7, 2014.
FDA approves Gazyva for chronic lymphocytic leukemia [press release]. FDA website; November 1, 2013. www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm373209.htm. Accessed January 7, 2014.
Gazyva [prescribing information]. Genentech; November 2013. www.gene.com/download/pdf/gazyva_prescribing.pdf. Accessed January 7, 2014.
Imbruvica [prescribing information]. Pharmacyclics; November 2013. www.imbruvica.com/downloads/Prescribing_Information.pdf. Accessed January 7, 2014.
FDA approves Imbruvica for rare blood cancer [press release]. FDA website; November 13, 2013. www.fda.gov/newsevents/newsroom/pressannouncements/ucm374761.htm. Accessed January 7, 2014.
Bristol-Myers Squibb receives US FDA sNDA approval for use of Sustiva (efavirenz) in HIV-1 infected pediatric patients [press release]. Bristol Myers Squibb; May 3, 2013. http://news.bms.com/press-release/rd-news/bristol-myers-squibb-receives-us-fda-snda-approval-use-sustiva-efavirenz-hiv-1. Accessed January 8, 2014.
Tivicay [prescribing information]. Viiv; August 2013. www.viivhealthcare.com/media/58599/us_tivicay.pdf. Accessed January 8, 2014.
FDA approves new drug to treat HIV infection [press release]. FDA website; August 12, 2013. www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm364744.htm. Accessed January 8, 2014.
FDA approves new treatment for hepatitis C virus [press release]. FDA website; November 22, 2013. www.fda.gov/newsevents/newsroom/pressannouncements/ucm376449.htm. Accessed January 8, 2014.
Olysio [prescribing information]. Janssen Therapeutics; November 2013. www.olysio.com/shared/product/olysio/prescribing-information.pdf. Accessed January 8, 2014.
FDA approves Sovaldi for chronic hepatitis C [press release]. FDA website; December 6, 2013. www.fda.gov/newsevents/newsroom/pressannouncements/ucm377888.htm. Accessed January 8, 2014.
Sovaldi [prescribing information]. Gilead; December 2013. www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.pdf. Accessed January 8, 2014.
Related Articles
Merck's Hepatitis C Combination Candidate Receives Priority Review
The FDA has granted priority review to Merck's chronic hepatitis C virus (HCV) treatment candidate grazoprevir/elbasvir.
Hepatitis C Combination Therapy Seeks Label Update
Janssen is asking the FDA to update the label of its once-daily hepatitis C virus (HCV) drug simeprevir (Olysio).
Generic Targretin Now Available in US
The first generic version of Valeant's bexarotene (Targretin) is now available from Mylan.
First Generic Axert Migraine Treatment Launched by Teva
Teva has launched the first generic version of Janssen's Axert migraine treatment.
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Gel Blood In Tube (ref: 12049)
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One tube of fake blood, an ideal accessory for vampires but can be used with any of our Halloween costumes.
November 16, 2014, by Kelly C - Mid Glamorgan, UK - United Kingdom
This was the best fake blood I've ever used. The gloppy consistency was fantastic and made a very realistic addition to the Halloween make up.
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Ongoing Reflection is reflection that occurs Before: Setting Goals (Planning) During: Monitoring Progress (Reviewing) After: Self-Evaluation/Reflection (Reporting & Reflection on outcomes) Supervisor Evaluation (Reporting) 1 – Commit to a 3 month training period of 3 sessions per week for one hour per session. 2 – Reduce the fat content of my body from 13.4% to 10%. 3 – Increase weights totals by 50%. 4 – Learn new weight training techniques and exercises. • Increased your awareness of your own strengths and areas for growth. • Undertaken new challenges • Planned and initiated activities. • Worked collaboratively with others. • Shown perseverance and commitment in your activities. • Engaged with issues of global importance. • Considered the ethical implications of your actions. • Developed new skills. Training diary – every weights session I do I write down my totals in my training diary eg Bicep Curls – 10 x 13kg, 10 x 14kg, 8 x 15kg I do this as part of my training , at the end of every exercise as I rest so it becomes natural. After every session I also write a few lines in the weight training journal I have set up in CAS Manager . 06/09/09 - Today I trained chest and biceps. I had a poor nights sleep last night and my energy levels were pretty low but I worked as hard as I could to get over this. I'm starting to feel a lot stronger and can see the reduction in my body fat content already after only 3 weeks! From my training diary figures I can also see that I have increased the amount I'm bench pressing by 15% which is a real achievement. It looks like I may have overestimated my ability though and a 50% overall weights increase over the 3 months is too difficult a goal. I'm therefore going to adapt my goals and change goal number 4 to 30%. It's still a difficult goal but a lot more realistic. •A significant piece of work and the most important part of your CAS activity evidence. • Write a short description of the activity. What you did, where you did it and how long it lasted. • Talk about your goals, not just whether or not you achieved them but how you achieved them. • Talk about the CAS learning outcomes, and how you achieved them Reflect on how this has developed you personally. Use the following questions to help you do this. and use them as the basis for your reflection. In what way has this activity developed me as a person? What have I learned about myself by doing this? What would I have done differently if I had a chance to take part in this activity again? I chose to take part in a weight training activity at the Sultan's School fitness suite. I have trained on a regular basis for years but I haven't trained for a while and I'm starting to become out of shape. I set myself four goals which were simple and easily measureable but still quite hard to achieve. Goal 1 – Commit to a 3 month training period for 3 sessions per week of one hours duration per session. I committed myself to a 3 month programme and I achieved this, I started the activity on the second of January 2009 and finished on the first of April 2009. The second part of the goal of training 3 times per week for one hour per session was not so easily achieved and I have to be honest and say that I didn't always do this. I didn't train 3 times per week on 2 occasions but I'm pretty pleased that for the most part I did what I said I would and feel that overall I have achieved my goal. I have additional evidence of achieving this goal and have uploaded my training diary to show the hours I worked. Goal 2 – Reduce the fat content of my body from 13.4% to 10% or less. My second goal the fat reduction was also achieved and I'm actually down to 9.5% total body fat which for me is great. I achieved this goal by doing the following. • Healthy eating with only a bit of cheating when I've eaten junk food on my cheat day. Eating healthily ALL the time is very hard and so I had a cheat day where I could have a McDonalds or a couple of chocolate bars just to keep me going. I always made sure I didn't eat too much junk though as that would ruin the hard work I'd put in for the rest of the week. • I spent time after my weights workout on the cardio machines and chose a fat burning programme. The Cross Trainer was particularly good for this. Goal 3 – Increase weights totals by 50%. My third goal was to increase the weights from the start of the 3 months to the end by 50% but only 3 weeks in, it became obvious I'd overestimated my ability. I dropped this down to 30% which was a lot more realistic and I have achieved this. Overall I've increased the total amount of weight I use in the gym by 35%. My training diary which I've uploaded onto CAS Manager shows the weights progression over the 3 months. Goal 4 – Learn new weight training techniques and exercises. After years of working in gyms my routine had become a bit boring so I wanted to try new things this time. I spent time on the internet and found quite a few new exercises and techniques I could try. Some of these included • Squats – I've had problems with my knees in the past so I wanted to develop my legs. This worked really well and my legs are much stronger now. • Dead lifts – My back hasn't been developing as well as my chest so I wanted to try something new and the dead lift is supposed to be the best back exercise you can do- it really worked! In reference to the CAS learning outcomes I feel I have achieved all of these too. Awareness of strengths and areas for growth - I gained a better understanding about my strengths and areas for growth. I've found that an area of strength for me in the gym is my triceps which I find very easy but due to rugby injuries my shoulders are a weaker area. I had to adapt my training to fit around this and chose exercises which develop but don't do any additional damage to that particular muscle group. Planned and initiated activities - I planned and initiated activities because I had to organise my training sessions. I had a set routine for each time I trained depending on what day it was. Saturday I did chest and biceps, Monday I did back, shoulders and triceps and Wednesday I did legs. My training diary also really helped me and I knew every session what I had to do next in terms of which weight to use. Worked collaboratively with others - I had a training partner so I had to work collaboratively with others and again this really helped me because we were able to push each other to work with heavier weights and therefore gained strength. It was also good to do this because it's safer to have a partner who can work with you in the gym to help you with the weights, to tell you if you are doing something wrong and to encourage you. Developed new skills - Although this wasn't a new challenge for me I did learn new weight training skills and techniques and also developed existing ones. I'm now very confident in using the Smith machine to do squats and dead lifts and my back and legs have really developed as a result. Show perseverance and commitment - When the training became hard I kept going, missing very few sessions and therefore showed perseverance and commitment. Sometimes if I'd had a bad day or not enough sleep the night before I didn't feel like training but I made myself go. It was also good to have a training partner for this as I would have felt I was letting him down otherwise. Overall I feel I have really benefitted from this activity. I am in much better shape physically and feel a lot more confident in myself. I also feel that as a result of having to plan my sessions with the help of the information I had gathered from previous workouts I am a lot more organised in the gym. I hope this will be of use to me in my schoolwork when planning my time for homework and revision . As far as what I've learned about myself, I think this has taught me that I work well with others and even when things get difficult I don't give up. If I had the chance to do it all again I think I would have put in a bit more time on the cardio machines to lose a little bit more fat. I'd also have spent more time doing abdominal work but I will be starting a new weight training activity in a few weeks and will make sure I do that next time. Remember the evaluation above is the MINIMUM. A really good self evaluation and reflection will not only describe what you did and how you achieved your goals and the IB learning outcomes, but will also aim to develop the reflection aspect. The best way to do this would be to use the additional questions listed below. CAS is all about YOUR personal development so try to focus less on being really descriptive regarding what you did (it's not a long journal entry) and reflect more on how this has developed you personally. •What did you hope to accomplish by participating in this activity? What did you actually accomplish? • What difficulties did you encounter? Did you feel at any stage that you were failing to achieve what you wanted from this activity? •What did you hope to learn from this activity, about yourself, about others, or about academic subjects? (For example: self-confidence, modesty, respect, awareness, responsibility, curiosity, honesty, objectivity, commitment, initiative, determination, new skills and the ability to meet new challenges.) • Did anyone help you during this activity? If so, describe the help given. • How did this activity benefit other people or institutions? (only relevant to Service activities) • What would you change if you did this same activity again? • What would you like to do next if you could continue with this activity? www.cas.tssnet.org
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Eldercare Locator Connects older Americans and their caregivers with sources of information on senior services. Family Caregiver Alliance Founded in 1977, Family Caregiver Alliance was the first community-based nonprofit organization in the country to address the needs of families and friends providing long-term care at home. FCA now offers programs at national, state and local levels to support and sustain caregivers. FamilyCareAmerica.com "This web site offers assistance for families providing home care for the elderly or chronicly ill by providing suggestions of how to deal with the inevitable problems that may crop up. There are fact sheets on topics such as legal issues, emotional issues and long-distance care as well as health and physical issues designed to make the caregiving relationship less stressful." Independent Living This report from AARP presents a new agenda for examining, building and retrofitting our communities to support successful aging. National Alliance for Caregiving The National Alliance for Caregiving is dedicated to providing support to family caregivers and the professionals who help them and to increasing public awareness of issues facing family caregivers. National Family Caregivers The National Family Caregivers Association educates, supports, empowers and speaks up for the more than 50 million Americans who care for loved ones with a chronic illness or disability or the frailties of old age. SeniorLink A site devoted to helping seniors maintain independence in their own homes with safety and dignity.
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Rhythmic - Page 8
Pizza Topped With Frogs, Pigs and Pythons Will Fill You Up and Gross You Out
Two Students Injured in New Mexico Middle School Shooting [UPDATED]
Shots were fired at Berrendo Middle School in Roswell, New Mexico, Tuesday morning.
New Movies: 'The Legend of Hercules,' 'Lone Survivor,' 'Her'
Two of these ('Lone Survivor,' 'Her') aren't technically opening this weekend, but they are expanding to many more theaters. That, along with the year's first Hercules flick (yup, there's another one coming in July) and the recent slew of high-quality holiday releases, make for a very crowded cineplex.