text:
Methods of inhibiting vascular smooth muscle cell migration comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independently hydrogen, ##STR2## wherein Ar is optionally substituted phenyl; R2 is pyrrolidino, hexamethyleneimino, or piperidino; and pharmaceutically acceptable salts and solvates thereof.
1. A method of treating vascular smooth muscle cell migration comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula ##STR6## wherein R1 and R3 are independently hydrogen, ##STR7## wherein Ar is optionally substituted phenyl; R2 is pyrrolidino, hexamethyleneimino, or piperidino; and pharmaceutically acceptable salts and solyates thereof.
2. The method of claim 1 wherein said compound is the hydrochloride salt thereof.
3. The method of claim 1 wherein said compound ##STR8## or its hydrochloride salt.
4. The method of claim 1 wherein said administration is for treatment of atherosclerosis, restenosis, inflammation, or malignant invasion.
Cell migration plays an important role in wound healing, inflammation, adult respiratory distress syndrome, and malignant invasion (Savani et al., J, Clin, Invest. 95: 1158-1168, 1995; Kullmann et al.: Am J. Respir. Cell. Mol. Biol. 8: 83-88, 1993; Brooks et al., Cell: 79, 1157-1164, 1994). Migration of vascular smooth muscle cells from media to intima plays a critical role in neointima formation leading to the pathogenesis of vascular disease such as atherosclerosis, restenosis following PTCA, and vein bypass atherosclerosis (Jackson et al., Arteriosclerosis and Thrombosis 13: 1218-1226, 1993; Brown et al., Cardiovascular Res. 28: 1815-1820, 1995; Bell and Madri, Am. J. Pathol. 137: 7-12, 1990). Use of antibodies to growth factors stimulating smooth muscle cell migration or peptides that block integrin mediated cell migration have been found to inhibit neointima formation in animal models of vascular injury (Ferns et al., Science 253: 1129-1132, 1991., Choi et al., J. Vasc. Surg. 19: 125-135, 1994).
Vascular restenosis after percutaneous transluminal coronary angioplasty (PTCA) has been shown to be a tissue response characterized by an early and late phase. Thrombosis and/or vasospasms may contribute to the early phase occuring hours to days after PTCA. The late phase appears to be dominated by SMC migration, proliferation and vascular remodeling. In this disease, the increased SMC accumulation by migration from media to intima contributes significantly to the pathogenesis of the disease. The excessive proliferation and migration of vascular smooth muscle cells may be the primary mechanism to the reocclusion of coronary arteries following PTCA, atherectomy, laser angioplasty and arterial bypass graft surgery. See "Intimal Proliferation of Smooth Muscle Cells as an Explanation for Recurrent Coronary Artery Stenosis after Percutaneous Transluminal Coronary Angioplasty," Austin et al., Journal of the American College of Cardiology 8:369-375 (Aug. 1985).
Vascular restenosis remains a major long term complication following surgical intervention of blocked arteries by percutaneous transluminal coronary angioplasty (PTCA), atherectomy, laser angioplasty and arterial bypass graft surgery. In about 35% of the patients who undergo PTCA, reocclusion occurs within three to six months after the procedure. The current strategies for treating vascular restenosis include mechanical intervention by devices such as stents or pharmacologic therapies including heparin, low molecular weight heparin, coumarin, aspirin, fish oil, calcium antagonist, steroids, and prostacyclin. These strategies have failed to curb the reocclusion rate and have been ineffective for the treatment and prevention of vascular restenosis. See "Prevention of Restenosis after Percutaneous Transluminal Coronary Angioplasty: The Search for a `Magic Bullet`," Hermans et al., American Heart Journal 122: 171-187 (July 1991).
In the pathogenesis of restinosis excessive cell proliferation and migration occurs as a result of growth factors produced by cellular constituents in the blood and the damaged arterial vessel wall which mediate the proliferation of smooth muscle cells in vascular restenosis.
Agents that inhibit the migration of smooth muscle cells are useful in the treatment and prevention of restenosis. The present invention provides for the use of compounds as smooth muscle cell migration inhibitors.
The invention provides a method of inhibiting vascular smooth muscle cell migration in a human or other mammal subject comprising administering to said subject a pharmaceutically effective dose of a compound of the formula ##STR3##
wherein R1 and R3 are independently hydrogen, ##STR4## wherein Ar is optionally substituted phenyl;
R2 is pyrrolidino, hexamethyleneimino, or piperidino; and pharmaceutically acceptable salts and solvates thereof.
The current invention concerns the discovery that a select group of compounds, those of formula I are useful for inhibiting vascular smooth muscle cell migration. The methods of treatment provided by this invention are practiced by administering to a human or other mammal in need a dose of a compound of formula I or II, or a pharmaceutically acceptable salt or solvate thereof, that is effective to inhibit vascular smooth muscle cell migration.
The term "inhibit" is defined to include its generally accepted meaning which includes phrophylactically treating a human subject to incurring smooth muscle cell migration, and holding in check and/or treating existing smooth muscle cell migration. As such, the present method includes both medical therapeutic and/or prophylactic treatment, as appropriate.
Generally, the compound is formulated with common excipients, diluents or carriers, and compressed into tablets, or formulated as elixirs or solutions for convenient oral administration, or administered by the intramuscular or intravenous routes. The compounds can be administered transdermally, and may be formulated as sustained release dosage forms and the like.
The compounds of formula I used in the methods of the current invention can be made according to established procedures, such as those detailed in U.S. Pat. Nos. 4,133,814, 4,418,068, and 4,380,635 all of which are incorporated by reference herein. In general, the process starts with a benzo[b]thiophene having a 6-hydroxyl group and a 2-(4-hydroxyphenyl) group. The starting compound is protected, alkylated, and deprotected to form the formula I compounds. Examples of the preparation of such compounds are provided in the U.S. patents discussed above.
Included in the invention is the use of the following compounds: ##STR5##
Substituted phenyl includes phenyl substituted once or twice with C1 -C6 alkyl, C1 -C4 alkoxy, hydroxy, nitro, chloro, fluoro, or tr(chloro or fluoro)methyl.
The compounds used in the methods of this invention form pharmaceutically acceptable acid and base addition salts with a wide variety of organic and inorganic acids and bases and include the physiologically acceptable salts which are often used in pharmaceutical chemistry. Such salts are also part of this invention. Typical inorganic acids used to form such salts include hydrochloric, hydrobromic, hydroiodic, nitric, sulfuric, phosphoric, hypophosphoric and the like. Salts derived from organic acids, such as aliphatic mono and dicarboxylic acids, phenyl substituted alkanoic acids, hydroxyalkanoic and hydroxyalkandioic acids, aromatic acids, aliphatic and aromatic sulfonic acids, may also be used. Such pharmaceutically acceptable salts thus include acetate, phenylacetate, trifluoroacetate, acrylate, ascorbate, benzoate, chlorobenzoate, dinitrobenzoate, hydroxybenzoate, methoxybenzoate, methylbenzoate, o-acetoxybenzoate, naphthalene-2-benzoate, bromide, isobutyrate, phenylbutyrate, β-hydroxybutyrate, butyne-1,4-dioate, hexyne-1,4-dioate, caprate, caprylate, chloride, cinnamate, citrate, formate, fumarate, glycollate, heptanoate, hippurate, lactate, malate, maleate, hydroxymaleate, malonate, mandelate, mesylate, nicotinate, isonicotinate, nitrate, oxalate, phthalate, teraphthalate, phosphate, monohydrogenphosphate, dihydrogenphosphate, metaphosphate, pyrophosphate, propiolate, propionate, phenylpropionate, salicylate, sebacate, succinate, suberate, sulfate, bisulfate, pyrosulfate, sulfite, bisulfite, sulfonate, benzene-sulfonate, p-bromophenylsulfonate, chlorobenzenesulfonate, ethanesulfonate, 2-hydroxyethanesulfonate, methane-sulfonate, naphthalene-1-sulfonate, naphthalene-2-sulfonate, p-toluenesulfonate, xylenesulfonate, tartarate, and the like. A preferable salt is the hydrochloride salt.
The pharmaceutically acceptable acid addition salts are typically formed by reacting a compound of formula I with an equimolar or excess amount of acid. The reactants are generally combined in a mutual solvent such as diethyl ether or benzene. The salt normally precipitates out of solution within about one hour to 10 days and can be isolated by filtration or the solvent can be stripped off by conventional means.
Bases commonly used for formation of salts include ammonium hydroxide and alkali and alkaline earth metal hydroxides, carbonates and bicarbonates, as well as aliphatic and aromatic amines, aliphatic diamines and hydroxy alkylamines. Bases especially useful in the preparation of addition salts include ammonium hydroxide, potassium carbonate, sodium bicarbonate, calcium hydroxide, methylamine, diethylamine, ethylene diamine, cyclohexylamine and ethanolamine.
The pharmaceutically acceptable salts generally have enhanced solubility characteristics compared to the compound from which they are derived, and thus are often more amenable to formulation as liquids or emulsions.
Pharmaceutical formulations can be prepared by procedures known in the art. For example, the compounds can be formulated with common excipients, diluents, or carriers, and formed into tablets, capsules, suspensions, powders, and the like. Examples of excipients, diluents, and carriers that are suitable for such formulations include the following: fillers and extenders such as starch, sugars, mannitol, and silicic derivatives; binding agents such as carboxymethyl cellulose and other cellulose derivatives, alginates, gelatin, and polyvinyl pyrrolidone; moisturizing agents such as glycerol; disintegrating agents such as agaragar, calcium carbonate, and sodium bicarbonate; agents for retarding dissolution such as paraffin; resorption accelerators such as quaternary ammonium compounds; surface active agents such as cetyl alcohol, glycerol monostearate; adsorptive carriers such as kaolin and bentonite; and lubricants such as talc, calcium and magnesium stearate, and solid polyethyl glycols.
The compounds can also be formulated as elixirs or solutions for convenient oral administration or as solutions appropriate for parenteral administration, for instance by intramuscular, subcutaneous or intravenous routes. Additionally, the compounds are well suited to formulation as sustained release dosage forms and the like. The formulations can be so constituted that they release the active ingredient only or preferably in a particular part of the intestinal tract, possibly over a period of time. The coatings, envelopes, and protective matrices may be made, for example, from polymeric substances or waxes.
The particular dosage of a compound of formula I required to inhibit smooth muscle cell migration according to this invention will depend upon the severity of the condition, the route of administration, and related factors that will be decided by the attending physician. Generally, accepted and effective daily doses will be from about 0.1 to about 1000 mg/day, and more typically from about 50 to about 200 mg/day. Such dosages will be administered to a subject in need of treatment from once to about three times each day, or more often as needed to effectively inhibit smooth muscle cell migration.
The local delivery of inhibitory amounts of active compound for the treatment of vascular smooth muscle cell migration or restinosis can be by a variety of techniques which administer the compound at or near the affected site. Examples of local delivery techniques are not intended to be limiting but to be illustrative of the techniques available. Examples include local delivery catheters, site specific carriers, implants, direct injection, or direct applications.
Local delivery by a catheter allows the administration of a pharmaceutical agent directly to the affected lesion. Examples of local delivery using a balloon catheter are described in EPO 383 492 A2 and U.S. Pat. No. 4,636,195 (Wolinsky, Jan. 13, 1987).
Local delivery by an implant describes the surgical placement of a matrix that contains the pharmaceutical agent into the lesion. The implanted matrix releases the pharmaceutical agent by diffusion, chemical reaction, or solvent activators. Lange, Science 249: 1527-1533 (September, 1990).
An example of local delivery by an implant is the use of a stent. Stents are designed to mechanically prevent the collapse and reocclusion of the coronary arteries. Incorporating a pharmaceutical agent into the stent delivers the drug directly to the affected site. Local delivery by this technique is described in Kohn, Pharmaceutical Technology (October, 1990).
Another example is a delivery system in which a polymer that contains the pharmaceutical agent is injected into the lesion in liquid form. The polymer then cures to form the implant in situ. This technique is described in PCT WO 90/03768 (Donn, Apr. 19, 1990).
Another example is the delivery of a pharmaceutical agent by polymeric endoluminal sealing. This technique uses a catheter to apply a polymeric implant to the interior surface of the lumen. The pharmaceutical agent incorporated into the biodegradable polymer implant is thereby released at the surgical site. It is descibed in PCT WO 90/01969 (Schindler, Aug. 23, 1989).
A final example of local delivery by an implant is by direct injection of vesicles or microparticulates into the affected site. These microparticulates may be composed of substances such as proteins, lipids, carbohydrates or synthetic polymers. These microparticulates have the pharmaceutical agent incorporated throughout the microparticle or over the microparticle as a coating. Delivery systems incorporating microparticulates are described in Lange, Science 249: 1527-1533 (September, 1990) and Mathiowitz, et al., J. App. Poly. Sci., 26:809 (1981).
Local delivery by site specific carriers describes attaching the pharmaceutical agent to a carrier which will direct the drug to the lesion. Examples of this delivery technique includes the use of carriers such as a protein ligand or a monoclonal antibody. Lange, Science 249: 1527-1533 (September).
Local delivery by direct application includes the use of topical applications. An example of a local delivery by direct application is applying the pharmaceutical agent directly to the arterial bypass graft during the surgical procedure.
It is usually preferred to administer a compound of formula I in the form of an acid addition salt, as is customary in the administration of pharmaceuticals bearing a basic group, such as the piperidino ring. It is also advantageous to administer such a compound by the oral route to an aging human (e.g. a post-menopausal female). For such purposes the following oral dosage forms are available.
In the formulations which follow, "Active ingredient" means a compound of formula I.
Hard gelatin capsules are prepared using the following:
______________________________________Ingredient Quantity (mg/capsule)______________________________________Active ingredient 0.1-1000Starch, NF 0-650Starch flowable powder 0-650Silicone fluid 350 centistokes 0-15______________________________________
The ingredients are blended, passed through a No. 45 mesh U.S. sieve, and filled into hard gelatin capsules.
Examples of specific capsule formulations of the compound of formula 1 wherein the compound is raloxifene, include those shown below:
______________________________________Ingredient Quantity (mg/capsule)______________________________________Raloxifene 1Starch, NF 112Starch flowable powder 225.3Silicone fluid 350 centistokes 1.7______________________________________
______________________________________Ingredient Quantity (mg/capsule)______________________________________Raloxifene 5Starch, NF 108Starch flowable powder 225.3Silicone fluid 350 centistokes 1.7______________________________________
______________________________________Ingredient Quantity (mg/capsule)______________________________________Raloxifene 10Starch, NF 103Starch flowable powder 225.3Silicone fluid 350 centistokes 1.7______________________________________
______________________________________Ingredient Quantity (mg/capsule)______________________________________Raloxifene 50Starch, NF 150Starch flowable powder 397Silicone fluid 350 centistokes 3.0______________________________________
The specific formulations above may be changed in compliance with the reasonable variations provided.
A tablet formulation is prepared using the ingredients below:
______________________________________Ingredient Quantity (mg/tablet)______________________________________Active ingredient 0.1-1000Cellulose, microcrystalline 0-650Silicon dioxide, fumed 0-650Stearate acid 0-15______________________________________
The components are blended and compressed to form tablets.
Alternatively, tablets each containing 0.1-1000 mg of active ingredient are made up as follows:
______________________________________Ingredient Quantity (mg/tablet)______________________________________Active ingredient 0.1-1000Starch 45Cellulose, microcrystalline 35Polyvinylpyrrolidone 4(as 10% solution in water)Sodium carboxymethyl cellulose 4.5Magnesium stearate 0.5Talc 1______________________________________
The active ingredient, starch, and cellulose are passed through a No. 45 mesh U.S. sieve and mixed thoroughly. The solution of polyvinylpyrrolidone is mixed with the resultant powders which are then passed through a No. 14 mesh U.S. sieve. The granules so produced are dried at 50�-60� C. and passed through a No. 18 mesh U.S. sieve. The sodium carboxymethyl starch, magnesium stearate, and talc, previously passed through a No. 60 U.S. sieve, are then added to the granules which, after mixing, are compressed on a tablet machine to yield tablets.
Suspensions each containing 0.1-1000 mg of medicament per 5 mL dose are made as follows:
______________________________________Ingredient Quantity (mg/5 ml)______________________________________Active ingredient 0.1-1000 mgSodium carboxymethyl cellulose 50 mgSyrup 1.25 mgBenzoic acid solution 0.10 mLFlavor q.v.Color q.v.Purified water to 5 mL______________________________________
The medicament is passed through a No. 45 mesh U.S. sieve and mixed with the sodium carboxymethyl cellulose and syrup to form a smooth paste. The benzoic acid solution, flavor, and color are diluted with some of the water and added, with stirring. Sufficient water is then added to produce the required volume.
Compounds of the invention have capacity to inhibit vascular smooth cell migration, as evidenced by the following.
Porcine aorta were obtained from freshly slaughtered male castrated hogs at a local slaughterhouse. Smooth muscle cells were prepared using a procedure similar to that described previously (Bonin et al., 1989) Briefly, the aorta was cut longitudinally, and the endothelium was removed by gently scraping the lumen surface with a razor blade. The aorta was then washed several times in sterile growth medium consisting of Dubecco's Modified Eagles Medium (DMEM), 10% Fetal Bovine Serum, L-glutamine (2 mM), penicillin (100 U/ml), and streptomycin (100 ug/ml). The strips of medial smooth muscle cells were then peeled away from the adventitia and cut into 1-2 mm pieces. The explants were placed in 24 well culture dishes containing the above growth medium. Cells were observed growing from the explants within 5-7 days. After 10-14 days, the explants were removed, the cells were trypsinized, and subcultured in T75 flasks containing 15 ml of the growth medium.
Human coronary and aortic smooth muscle cells were purchased from Clonetics Corporation (San Diego, Calif.). Both cell types were cultured in growth medium as described for porcine smooth muscle cells.
Directed migration of smooth muscle cells, derived from porcine and human arteries, toward a gradient of platelet-derived growth factor was performed using a modified Boyden's chamber employing a 96 transwell system and polycarbonate filters with 8 um pores (Neuro Probe, Inc., Cabin John, N.J.). Smooth muscle cells grown in T75 flasks, were transferred to phenol red free Dubecco's Modified Eagles/F12 Medium (DMEM/F-12) containing 2% Fetal Bovine Serum, L-glutamine (2 mM), penicillin (100 U/ml), and streptomycin (100 ug/ml). After 24 hours, cells were trypsinized using phenol red free trypsin/EDTA (Gibco, BRL). The cells (2.5�10-6 cells/ml) were suspended in phenol-red free DMEM/F12 containg 1% platelet poor plasma, and various concentrations of compounds of formula I. One hundred uL of the cell suspension were added to the upper wells of the modified Boyden chamber. The wells of the lower chamber were filled with 43 ul of DMEM/F-12 containg 1% plate poor plasma, 5ng/ml PDGF and various concentration of compounds. The chambers were incubated at 37� C. in 5% CO2 for 5 hours. The migration membrane was removed from the chamber and the cells from the upper side of the membrane were removed with a cotton swab. The cells migrated to the lower side of the membrane were fixed in methanol and stained with Diff-Quick staining solution (Baxter). Cell migration was quantified either spectrophotometically using a microtiter plate reader (ThermoMax, Molecular Dynamics, Inc.) or by counting the cells in a 40� high power field (HPF) using an inverted microscope (Nikon, Inc.).
For the experiments involving preincubation of cells with the compound, drug was placed into the pretreatment medium at the indicated concentrations, in separate flasks, and incubated for 18 hours. The assay conditions of the cells in these pretreatment experiments were exactly the same as those used in the experiments described for acute drug effects.
TABLE I______________________________________Stimulation of Porcine Aortic Smooth Muscle Cell (SMC)Migration by Platelet-Derived Growth Factor (PDGF) SMC MigrationPDGF (ng/ml) (O.D. 650 nm)______________________________________0.04 0.016 � 0.0080.80 0.009 � 0.0031.50 0.013 � 0.0073.00 0.028 � 0.0086.00 0.058 � 0.01012.0 0.052 � 0.00725.0 0.047 � 0.009______________________________________
TABLE II______________________________________Inhibition of PDGF Induced Porcine Aortic SMCMigration by Compound A* and β-EstradiolSMC Migration (O.D. 650 nm)Concentration (nM) Compound A β-Estradiol______________________________________0.0 0.053 � 0.015 0.053 � 0.0150.1 0.035 � 0.005 0.032 � 0.0031.0 0.030 � 0.005 0.023 � 0.00310 0.032 � 0.007 0.034 � 0.006______________________________________ *Compound A is of the Formula I, where R1 and R3 are hydrogen and R2 is pyrrolidino.
Activity in the above indicates that the compounds of the invention are of potential in the inhibition of vascular smooth muscle cell migration and its effects.
Citas de patentes
Otras citas
Citada por
Eventos legales
Imagen original


text:
$14,114 – $17,420 Invoice
25 / 31 MPG City/Hwy
Enter your information and a representative will contact you for this 2006 Toyota Matrix !
What's New
Aside from the addition of a JBL premium sound system to the mid-range XR's option list, the Matrix is unchanged for 2006.
Now in its fourth model year, the Toyota Matrix is one of a growing class of models that combines the high seating position and large cargo bay of an SUV with the size, fuel economy, and sporty nature of a compact sedan. The Matrix was developed in conjunction with (and is mechanically identical to) the Pontiac Vibe, though the Matrix is built in Canada while the Pontiac Vibe is built alongside the Toyota Corolla at a joint Toyota-GM plant in Fremont, California. Despite its small size, the Matrix offers several SUV-like characteristics, such as a cargo area with a washable flat floor and a rear window that lifts independently of the tailgate. The rear seat splits and folds 60/40, and the front passenger seat can be folded down to serve as a table or increase carrying capacity. The Matrix's tall, upright front seating position gives the driver a commanding view of the road. And, like many SUVs, the Matrix offers the option of all-wheel drive (AWD).
The Matrix is available in Standard, XR, and XRS trim levels; all come with standard air conditioning, a CD player, and power mirrors. The XR adds power windows and locks, remote keyless entry, a height-adjustable driver's seat, and a rear wiper; many of these features are optional on the Standard model. Safety-related options include Toyota's Vehicle Stability Control system (automatic transmission only), side air bags, and anti-lock brakes. Power for the Standard and XR models comes from a 126-hp, 1.8L four-cylinder engine with variable valve timing. Front-wheel-drive models are available with either a 5-speed manual or 4-speed automatic transmission, while AWD models are exclusively equipped with automatics.
The XRS is the hot rod of the Matrix lineup. It has a 164-hp version of the 1.8L engine with a higher redline (7,800 RPM versus 6,000 for Standard and XR) and a variable valve-timing system tuned for high RPM power. A 6-speed manual is the sole transmission choice, and the XRS is available only with front-wheel drive. The XRS features the same standard equipment as the XR and adds four-wheel anti-lock disc brakes, a sport-tuned suspension, 16-inch alloy wheels, fog lamps, and special body trim bits to complete the go-faster look.
The Competition
The Toyota Matrix competes in the Compact Conventional segment against 17 other models from 14 different manufacturers. Entries in this segment continue to offer an ever-increasing package of safety, value, and comfort/convenience features while still delivering excellent fuel economy.
According to the J.D. Power and Associates Sales Report,SM calendar year 2005 sales leaders in this segment were the Honda Civic (308,415 units sold), the Matrix's platform mate Toyota Corolla (244,032), followed by the Chevrolet Cobalt (212,667). The Matrix finished 2005 just out of the top 10, selling 90,258 units during the calendar year to rank 11th in the segment.Other top sellers in the segment include the Ford Focus, Nissan Sentra, Hyundai Elantra, Toyota Prius, Volkswagen Jetta, Saturn ION, and Mazda3.
|City/Hwy MPG
|Base (M5)
|5 speed manual
|126-hp / 1.8L 4-cyl
|5 speed manual
|126-hp / 1.8L 4-cyl
|6 speed manual
|164-hp / 1.8L 4-cyl
$14,105–$17,880 Base MSRP
$13,047–$16,179 Invoice
26/34 MPG City/Hwy
$14,465–$16,315 Base MSRP
$13,525–$15,092 Invoice
24/32 MPG City/Hwy
$14,065–$15,915 Base MSRP
$13,151–$14,722 Invoice
24/32 MPG City/Hwy
$14,560–$22,240 Base MSRP
$13,327–$20,332 Invoice
23/32 MPG City/Hwy
$14,760–$24,440 Base MSRP
$13,509–$22,719 Invoice
28/38 MPG City/Hwy
$22,150–$23,650 Base MSRP
$20,250–$21,619 Invoice
49/51 MPG City/Hwy

subset: commoncrawl


text:
Below is the poem entitled Wonderland which was written by poet
Valencia. Please feel free to comment on this poem. However, please remember, PoetrySoup is a place of encouragement and growth.
Read Poems by
Deeana Valencia
Take me by the hand
Come with me to this far away land.
Where life as we know it comes to an end.let
We journey back in time
To a place that lives only in our minds.
Where the light shines so bright that it blinds.
The feelings of love ignite.
Let your mind lose control and take flight.
Begin this journey with me to Wonderland.
We travel hand in hand,
Without judgement, together we unite,
Without fear, we join for just one night.
The feeling of peace in the air,
Forget about worries,
Life without care.
Let the music take you there.
Move your feet to the rythym of the beat
Lose control for just one night.
Journey with me through Wonderland
A place never to forget.
Wonderland lives on tonight.
In my dreams,
I close my eyes and look towards the light.
A comment has not been posted for this poem. Encourage a poet by being the first to comment.


text:
A CG animation made as a joint project with Newcastle City Council, United Kingdom.
Following an initial team effort, a joint project was propose to stir public engagement in climate change policies. The discourse is targeted to the life style improvements deriving from insulation. Three clips are to be presented, each one of them considering aspects of how insulation means comfort whilst preserving an architectural uniqueness of the chosen spot.
Featured video considers technical aspects regarding insulation process, whilst giving subtle messages on improvement of quality of life.
You can find a formal analysis followed by conceptual storyboard after the break.
I have been invited to participate on ArchaID, a blog specialising on space interaction design and broader topics stemming from digital architecture. In my first post, I make an analysis on the topic of originality when considered in a computer aided perspective of design. Please read it in full here
In the featured image, me beautifully captured in a point cloud using a combination of depth and greyscale images.
Following an initial group effort, an actuated system was defined to be embeded in a rain harvesting system. As water collection is dependent upon the quality of runoff surface, the system would incorporate a mechanism to only open in the presence of rain. When closed, the structure would insulate catchment surface, this improving collected water quality.
This project functions as the input subsystem in order to equip the system with a sensing capability—the structure will be aware of when it is raining. Once a threshold is surpassed, a virtual and physical model is actuated.
Research paper after the break.
3d Production // lighting & rendering
Video portfolio of my work
Photography // Silver 35 mm
3D & Animation // Modelling, texturing & rendering


text:
Omni Scottsdale Resort & Spa at Montelucia
Near Camelback Mountain
In Arizona's Paradise Valley, Omni Scottsdale Resort & Spa at Montelucia places you a 10-minute drive from Camelback Mountain and 20 minutes by car from Phoenix Mountains Preserve. Downtown Scottsdale and The Scottsdale Museum of Contemporary Art are a 15-minute drive southeast.
Hike, climb, drive
You can hike remote, visually arresting trails, climb Camelback Mountain, or stroll among endemic flora at the Desert Botanical Garden, 17 minutes by car. Bob Bondurant School of High Performance Driving, a 40-minute drive south, offers high-octane track and karting experiences.
Spa indulgence
There are 3 pools on site, one at Joya Spa, which also offers a sauna, steam room, and hot tub; there's also a fitness center and extensive yoga program. Dining options include the AAA Four Diamond Prador restaurant, Mbar with tapas and live music, and CENTRO Lounge.
A divine night's sleep
The hotel's 293 rooms have WiFi, 42-inch HDTVs with iPod® docking stations, and feature patios or balconies with a chaise longue. Custom Devine Beds feature 300-thread-count Egyptian cotton sheets; bathrooms offer separate showers with deep soaking bathtubs. Self-parking at this hotel is complimentary.
Better than average property - not a 5* resort
Four nights here sadly reduced to three due to flight delay. A fantastic resort location…
Enter dates to check prices
Hotel Info: 800 1205131from S$172
- Premium Room, 1 King Bed (Camelback View )
- Premium Room, 2 Queen Beds (Camelback View)
- 1 King Bed, ADA Resort View Room
- Room, 1 King Bed, Accessible, Resort View
- 1 King Bed, Oasis Poolside Room
- Deluxe Room, 1 King Bed, Resort View
- Montelucia Signature Suite
- Montelucia Mountain View
- Executive Suite, One Sleeper Sofa Bed
- Camelback View Room One King Bed
- Grand Room, 1 King Bed, Mountain View
- 1 King Bed, Poolside Room
- Deluxe Room
- 1 King Bed, Camelback View Room
- 2 Queen Beds, Resort View Room
- Exclusive Room, 1 King Bed, Poolside
- Deluxe Room, 1 King Bed, Poolside
- Run of House (Limited Time Offer!)
- 2 Queen Beds, Oasis Poolside Room
- Room, 2 Queen Beds, Poolside
- 2 Queen Beds, Camelback View Room
- Room, Accessible, Resort View
- 1 King Bed, Resort View Suite
- Montelucia Resort View 2 Queens
- 1 King Bed, Oasis Poolside Suite
- 1 King Bed, Grand Mountain View Room
- Resort View
- 1 King Bed, Resort View Room
Recommended hotels
At a glance
Key facts
Hotel size
- This hotel has 293 rooms
- This hotel is arranged over 2 floors
- Check-in time starts at 4 PM
- Check-out time is noon
- Express check-out
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- Babysitting/childcare *
- Pets allowed *
- WiFi in public areas *
- WiFi in rooms *
- Free self parking
- Valet parking *
- Accessible parking
Nearby Five Star Paradise Valley hotels
In the hotel
- Cooked-to-order breakfast daily (surcharge)
- 5 restaurants
- Bar/lounge
- Coffee shop/café
- 24-hour room service
- Number of outdoor pools - 3
- 24-hour fitness facilities
- Full-service spa
- Spa treatment room(s)
- Bicycle rentals on site
- Hiking/biking trails nearby
- Health club
- Spa tub
- Steam room
- Sauna
- Business center
- Conference space
- Meeting rooms 23
- Conference space size (feet) - 27000
- Conference space size (meters) - 2508
- Conference center
- Computer station
- 24-hour front desk
- Concierge services
- Dry cleaning/laundry service
- Laundry facilities
- Hair salon
- Free newspapers in lobby
- Luggage storage
- Wedding services
- Elevator/lift
- ATM/banking
- Safe-deposit box at front desk
- Disabled parking
- Accessible path of travel
- Braille or raised signage
- Accessibility equipment for the deaf
- Accessible bathroom
- In-room accessibility
- Roll-in shower
In the room
- Climate control
- Air conditioning
- Ceiling fan
- Minibar
- Coffee/tea maker
- Bathrobes
- Iron/ironing board
- Blackout drapes/curtains
- Sofa bed size double
- Pillowtop mattress
- In-room massage available
- Furnished balcony or patio
- Private bathroom
- Deep soaking bathtub
- Rainfall showerhead
- Free toiletries
- Hair dryer
- 42-inch TV
- Pay movies
- Premium TV channels
- IPod docking station
- Free newspaper
- WiFi (surcharge)
- Phone
- Refrigerator (on request)
- Microwave (on request)
- Daily housekeeping
- In-room safe
- Connecting/adjoining rooms available
- Access via exterior corridors
Top Paradise Valley hotels
Recently reviewed hotels in Paradise Valley
- Fairfield Inn & Suites by Marriott Phoenix AirportFrom
"2-way free airport shuttle was good. Room was clean & bed was comfortable. Only negative is Hotel does not provide complimentary bottled water."Jun 22, 2015
- Holiday Inn Express Hotel & Suites Phoenix Downtown-BallparkFrom
"This is our 1st time in Arizona and the hotel is good. Will be back again."Jan 6, 2015
- Four Points by Sheraton Phoenix South MountainFrom
"This is a wonderful hotel for travellers like us who came from a right-hand driven vehicle country and do not wish to take the challenge of left-hand driving in a foreign land! We…"Dec 16, 2014
- Phoenix Marriott Tempe at The ButtesFrom
"Excellent! Will stay there again."Oct 31, 2014
Nearby hotels
Special features
Joya Spa has 19 treatment rooms including rooms for couples. Services include deep-tissue massages, hot stone massages, sports massages, and Swedish massages. A variety of treatment therapies are provided, including aromatherapy, hydrotherapy, and reflexology. The spa is equipped with a sauna, a spa tub, a steam room, and Turkish bath/hammam.
Children under 18 years old are not allowed in the spa without adult supervision. Guests under 16 years old are not allowed in the spa.
DiningPrado - This fine-dining restaurant specializes in Mediterranean cuisine and serves breakfast, lunch, and dinner.
Mbar - This bar specializes in Mediterranean cuisine and serves light fare only. Happy hour is offered.
Centro - This poolside restaurant serves light fare only. A children's menu is available.
Crave Cafe - This café serves breakfast and lunch.
Joya Terrace - This café serves breakfast and light fare.
Omni Scottsdale Resort & Spa at Montelucia's small print
Also known as
- Montelucia
- Scottsdale Resort Montelucia
- Intercontinental Montelucia Hotel
- Intercontinental Paradise Valley
- Montelucia Hotel Paradise Valley
- Montelucia Resort And Spa
- Montelucia Omni
- Montelucia Resort
- Montelucia Resort Scottsdale
- Montelucia Scottsdale Resort
- Omni Resort Montelucia
- Omni Scottsdale
- Omni Scottsdale Montelucia
- Omni Scottsdale Resort Montelucia
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
Children under 18 years old are not allowed in the spa without adult supervision.
Guests under 16 years old are not allowed in the spa.
Reservations are required for massage services and spa treatments and can be made by contacting the property before arrival at the number on the booking confirmation.
Mandatory fees
Pet deposit: USD 100
Optional extras
Valet parking costs USD 19.00 per night with in/out privileges
Rollaway beds are available for an additional charge
Cooked-to-order breakfast is offered for an extra charge of USD 15 per person (approximately)
Pets are allowed for an extra charge of USD 100.00 per pet, per stay
WiFi is available in guestrooms for USD 9.95 per night (rates may vary)
WiFi is available in public areas for USD 9.95 per day (rates may vary)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.


text:
PRINCETON, N.J. – The Holy Cross men's rowing team competed in two races at the Princeton Chase Regatta on Lake Carnegie on Sunday.
Holy Cross "A" placed 24th out of 38 boats in the varsity heavyweight eight race with a time of 14:02.243, while Holy Cross "B" finished 32nd with a time of 14:29.085. Princeton "A" won with a time of 13:06.187. The Crusaders (15:26.626) finished 26th out of 33 boats in the freshman eight race as Princeton "A" (13:23.992) placed first.
"We had a pretty good day at Princeton," said Holy Cross head coach Todd Pearson. "The varsity made up a lot of time on our competition compared to last week and if not for an equipment issue, could have been even faster. I was especially happy with the performance of the second varsity as it was probably the best showing by a HC second varsity since 2006-2007 and definitely the best during my tenure as head coach. They raced hard and beat a lot of really good crews. Our freshmen got their first taste of EARC competition and continue to improve every time they go out on the water. Racing this weekend should prepare them well for next weekend's green monster regatta."
The Crusaders return to action when they conclude the fall season at the Green Monster Regatta on Saturday, Nov. 6, in Hanover, N.H.
Varsity Heavyweight Eight Race
Holy Cross "A": Mary Carol Madigan (coxswain), Colin Hayes, Tom Gallant, Peter Dwyer, Trevor Zaleski, Peter Prominski, Dan Ryan, Nick Forgione, Kevin Moran.
Holy Cross "B": Steve Burison (coxswain), Paul Gaffney, Pat Rapuano, Mike Walker, Richard Sullivan, Andrew Cecchetti, Kevin Smith, Steve Raiola, Pete Haney.
Freshman Eight Race
Holy Cross: John Gentile (coxswain), Jordan Traub, Anthony Curro, Mike Lindsay, Leo Kennedy, Thomas Schoenberger, Henry Van Damme, Bryan Ptucha, Calvin Joewono.


text: All Duke players eligible for this year's draft—seniors Mason Plumlee , Seth Curry and Ryan Kelly —have received three of the 61 invitations to the NBA Combine, the league announced Thursday night. Curry and Kelly, both recovering from offseason surgeries, will not participate in workouts. Here is a list of all the ACC alumni headed to the May 15-19 workout in Chicago:


text:
LFO lead singer, Rich Cronin, passed away yesterday at a hospital. He had been battling leukemia for a while, and finally succumbed to a stroke. Rich was only 35 years old. This totally breaks our boy band loving heart. We're not ashamed to admit to being LFO fans; the three totally cute dudes popped up in the late 90's and their ridiculously catchy tune Summer Girls had us dancing at house parties all year. What would our teens have been without them? Our condolences to Rich's family and friends.
[Photo: Getty Images]


text:
Xavier enters the Golden Dome Invitational, hosted by Notre Dame, winners of its last two matches.
Sept. 13, 2012
CINCINNATI- Xavier travels to South Bend, Ind., for the Golden Dome Invitational, with matches against Notre Dame, Kansas and Loyola Marymount on the schedule. The Musketeers (7-4) will go for their third-straight win when they open play against Notre Dame on Friday night at 7:30 p.m.
The Last Meeting
September 4, 2009
Cintas Center
The Last Meeting
August 29, 2009
Murfreesboro, Tenn.
XU closes the tournament with two matches on Saturday, Kansas at 10:30 a.m. and Loyola Marymount at 7 p.m. Live stats for all matches and a live video stream for all matches against Notre Dame will be available.
Last Time Out
Xavier earned a runner-up finish in the University of Delaware Invitational last weekend. The Musketeers lost to Texas A&M in their opening match and won the last two contests against Columbia and Delaware in straight sets.
Agin Moves to Middle-Blocker
Makayla Agin made the switch from outside hitter to middle blocker prior to last Tuesday's match against Miami (OH). Agin is hitting .353 from her new position and has helped Xavier to a 3-1 record since changing positions
Dealing Aces
XU ranks third in the Atlantic 10 in aces (1.49 aces/s), with three Musketeers ranking in the top four individually: No. 1 Alex Blair (.42), No. 3 Sarah Brown (.41) and t-4th Aubree Smith (.38).
Scouting the Opposition - Notre Dame
• Notre Dame is 5-4, but three of the team's four losses have come to ranked opponents. ND lost to No. 17 San Diego and No. 5 USC in its last two matches.
• Team Leaders: Toni Alubgue (4.03 k/s), Maggie Brindock (7.62 a/s), Taylor Morey (4.56 d/s) and Marie Roof (.97 b/s).
• The Fighting Irish are hitting .248 and allowing opponents to hit .179 on the season.
Scouting the Opposition - Kansas
• The Jayhawks enter the Golden Dome Invitational on a seven-match winning streak, which includes winning the Jayhawk Invitational and the Kansas Volleyball Invitational.
• Team Leaders: Carolina Jarmoc (3.91 k/s and 1.41 b/s), Erin McNorton (12.50 a/s) and Brianne Riley (5.68 d/s).
• Kansas sports a .281 hitting percentage and limits opponents to only .145 hitting.
Scouting the Opposition - Loyola Marymount
• The Lions enter the Golden Dome Invitational with 6-3 record, winning their last two matches against George Mason and High Point.
• Team Leaders: Kathleen Luft (4.31 k/s), Hannah Tedrow (9.22 a/s), Betsi Metter (5.47 d/s) and Litara Keil (1.03 b/s).
• Loyola Marymount hits .251 and allows opponents to hit only .153.


text:
Legal Trade
A blog about lawyering with Mary Flood.
Monthly Archive for July, 2009
Still no local U.S. Attorney appointment
So while I was on vacation, a committee of lawyers met with six candidates for U.S. Attorney here in Houston. This is an updated version of the committee our two GOP U.S. Senators had back when a Republican was in the White House. Since a Democrat is now in the White House, one would think […] [Read More]


text:
Hang tight!
Recipe by GAIL BOYD
"Kids like this and will gobble it up!"
Hmm. None of these ingredients are on sale today.
Show ingredients on sale
Sort stores by
Save money at local stores when ingredients are on sale!
Watch video tips and tricks
1 tablespoon
vegetable oil
1/4 cup
chopped onion
hot dogs, sliced
1 (28 ounce) can
baked beans with pork
1 cup
1 tablespoon
prepared mustard
2 tablespoons
1/4 teaspoon
ground ginger
3/4 cup
shredded Cheddar cheese
I totally altered this recipe. My mother used to mix just the beans and hot dogs but I knew I wanted to add something else. I mixed all the ingredients except onion because I didn't have any into a casserole dish and I microwaved it til cooked through. I served it with brown bread. I really liked it with the applesauce and mustard. It gave it a sweet and sour taste. I gave it four stars because I'm not fond of hotdogs but the kids liked it. Very good.
This one has too much going on in it. The cheese and mustard flavors seemed out of place. Applesauce made it runny. Son picked out hot dogs and husband could hardly eat.
30 Ratings
My five year old said yum! five times, which rarely happens. I mixed up a box of Jiffy corn bread mix and put that on top of the beans THEN layed shredded pizza blend cheese on the top of that and mixed it into the cornbread just barely. Forty minutes and it made a casserole that fed three with leftovers. Very easy weeknight meal.
My kids gobbled this stuff up! Great meal for quick eats. Definately give this a thumbs up!
Excellent quick meal, very easy to do
I highly recommend using Bush's Steakhouse beans with this meal. The flavors all end up complimenting each other really well.
I liked it, my boys didn't. I did things a little differently- I sauteed a whole, small onion along with two large cloves of garlic until tender then added the thinly sliced hot dogs. Cooked until all was lightly browned then took it off the heat. For the sauce/bean portion I used one regular sized can of original recipe beans with pork, 3/4 cup homemade chai spiced applesauce, 1 tablespoon each Dijon style mustard/ketchup/maple bbq sauce and a little liquid smoke. Whisked it all up then stirred in the hot dog/onion/garlic mixture. Topped with cheese. I likely won't make this again since I'm the only one who will eat it ;) But if there were a next time, I wouldn't use the bbq sauce, liquid smoke or cheese. I'd keep the rest as I mentioned the same. Served with cornbread muffins.
Made it for the first time tonight while suffering from an Beanie-Weenie craving, and it was good! I used turkey franks and left the cheese off to bring the fat down, and dried onions instead of fresh since that's what I had.
It did turn out soupy, however, so I think next time I will make it on the stovetop and let it cook down a bit - that's the reason for the 4 instead of 5 stars.
* Percent Daily Values are based on a 2,000 calorie diet.
Beans and Franks Applesauce Bake
Serving Size: 1/6 of a recipe
Servings Per Recipe: 6
Amount Per Serving
Calories: 441
Calories from Fat: 233
Kale is the healthy, green leaf that transforms into a crunchy snack chip in your oven.
You can't go wrong choosing from over 400 pork chop recipes with ratings and tips!
Delicious recipes, party ideas, and cooking tips! Get a year of Allrecipes magazine for $7.99!
See how to make baked beans with bacon, diced apples, and brown sugar.
A perfect recipe for indoor BBQ chicken.
See how to make a simple breakfast casserole with eggs, ham, cheese, and veggies.


text:
More Info: www.facebook.com/Ak47Musical , The house scene today would be unimaginable without DJ Antoine. Always well turned out and being wooed by top sponsors (DaimlerChrysler, Campari, SKYY Vodka, Moonlight, Chupa Chups, J. Lindeberg, ..
Yves Larock is a frenzied self-taught producer and international DJ who has developed a highly distinctive and personal style in the last two years, with "Zookey" in 2005, "Rise up" in 2007 and the release of his new single "By your side" i..
Spring 2006: A team of DJs is celebrating its tenth anniversary and can look back on a decade in which one high was topped by the next. First they conquered Stuttgart, their home base, followed by the rest of Germany and then Ibiza. They ha..
Jaybee Während der ersten grossen Housewelle Mitte der 80er Jahre waren die legendären Zürcher Clubs "Flamingo" und "The Club" (heutiges OXA) Jaybee's zweite Heimat. Mit der damals schweizweit bekannten Break Dance Gruppe "Planet Force" ta..


text:
Incoming Students: Welcome to Marquette! If you're interested in learning more about the accommodations process, please call our office (414-288-1645). Our staff can help to explain the documentation necessary, the steps involved in requesting accommodations, and answer any questions you may have. If you're coming to campus, and would like to meet in-person, please call ahead so that we can set time aside to meet with you.
Current Students: Summer Accommodations -- If you're enrolled in summer session courses and would like to set up accommodations, please call the office!
Would you like to visit the office and learn about our services? Contact us


text:
Register now for free, or sign in with any of these services:
The luddites lost....and get ready for four more years republicants.
Sure, it's always the corporation or someone else's fault.
You betcha.
Where are the parents of these lovely teenagers?
In Jail?
Tough being a speck of red in a sea of blue eh?
Again, a total waste of a half million dollars each and every year....when will we learn.....the pyramid organizational structure that moves money to the top of the organization is history....get rid of the chancellor's office completely...move the money and decision making power down in the organization...where it belongs.
Whine, whine, whine.....the duckies got home field advantage for what reason?
Uncle Phil.
Bringing the brooms out in Corvallis was fun eh duckies?
Go Kent State!
Oh no! Lies, Lies and damned lies!
Sure, you betcha.
Jimmy, did you smoke your bong before posting?
What a ridiculous waste of space and time.
Now look Jimmy....reefer madness arguments just seem to come mostly from old folks like yourself...and yes, I am older than you Jimmy....so last year near Albany 600 folks were laid off from the paper mill and it is being torn down as we speak. The same technology could have been used to turn the mill into a hemp fiber processing plant. And no Jimmy....one can't get high off the hemp fiber.....and if we take a look at all of the low yield areas of our local farm land it would be easy to grow hemp....not dope Jimmy...hemp. Do your research Jimmy....reefer madness mentality is old school....very old.
Bring back Jack.
The Blazers are just a play thing to the billionaire.....and as long as the fans continue to purchase the mediocre product he has no incentive to change anything about his management style....and he won't.
So stop buying the tickets and watch what happens.
Yeah Sure JJJ....only in your conservative mind.
I'll stand up for Oregonians First Amendment rights anytime.
And a NIMBY is just a NIMBY.
You disgust me....you have absolutely no knowledge of mental health illness whatsoever...go crawl back into your hole and smoke your bong idiot.
"Mental health workers deal with the scariest, diseased, societal throw aways that none of you out there would dare say hello to"
Then you should quit immediately if you are still working for mental health.....your attitude is the issue. How dare you call my son, who has been on his meds and working with mental health to deal with schizophrenia on a daily basis for twenty years a societal throw away....you disgust me....leave the system, please.
Guess what...no one will look at any of your links...you are just wasting time.....get to work ok?
Not the same at all...occupations is a huge stretch...and a bigot is just a bigot.
Oh you mean the same book that the priests who abused my son read?
Take your 13th century "religion" and your views and put your head back into the sand...where it belongs.
Oregonians supported this bi partisan effort led by Tom McCall....you think that Oregonians would support your communist efforts at taking over residential homes owned by banks for public use? Get real...you couldn't hold Tom McCalls jock strap.
It's the banks house..get real....you want to live in a communist environment start your own commune....be your own guru and move to Antelope...oh, that's right....it was tried already...oh well.
You poor things!
Multiple what?
MBA, PHD. Bronze Star, 30 years at Hewlett Packard, retired with 4 million in the bank.....and you have no cred at all.
This is is so stupid....quit shooting from the hip with absolutely no research to support your bogus opinions....you are just a troller looking for attention.
Go on back to the dark ages please...the luddites lost.


text:
Easton Intermediate Stealth Speed Catcher's Chest Protector
$71.93 $119.99*
Save $48.06 (40%)
Product Information:
Take your protection behind the plate seriously with the Easton® Stealth Speed Chest Protector. This revolutionary design takes catcher's equipment to an entirely new level. The Stealth Speed Series has been anatomically engineered to ensure superior mobility and protection. Bio-Dri® fabric lining ensures you will stay cool and comfortable on those hot days, while ventilation portals help reduce the overall weight of the chest protector.
- Length: 16"
- Form-fitting, shoulder arch design provides maximum comfort, enhanced mobility and protective coverage
- Ultra-lightweight, maximum protective inner foams
- Comfort form memory foam layer to deaden a ball on impact
- Ventilation portals provide maximum weight reduction and cooling
- Bio-Dri® lining wicks away moisture for cool, dry comfort
- Double back adjustment offers custom fit
- Removable shoulder caps
- Removable/adjustable contoured throat shield
- Size: Intermediate (players ages 13-15)
- Model: A165062
- Easton
Country of Origin: ChinaWeb ID: 3984081
Customer Reviews:
Rated 4.5 out of 5�by 2 reviewers.
Rated 4 out of 5�by Dave Good buy Seems to be a good product only used twice since the purchase. May 25, 2013
Rated 5 out of 5�by chan i d buy it again son said its the best one he has ever had April 10, 2011
1-2 of 2


text:
Animal & Veterinary Science
Agricultural Sciences Bldg.
Phone: (208) 885-6345
Mailing Address:
Animal & Veterinary Science
University of Idaho
875 Perimeter Drive MS 2330
Moscow, ID 83844-2330
I joined the faculty of the Animal and Veterinary Science Department in 1985; at that time it was the Animal Science Department. My appointment for the first 20 years at the University of Idaho was 50 percent teaching and 50 percent research. For the last 5 years it has been my privilege to serve as the head of the Animal and Veterinary Science Department.
As a research and teaching faculty member, I was engaged in a broad spectrum of teaching and research activities that involved applied aspects of ruminant nutrition with particular emphasis on beef cattle. My teaching contributions have largely been in the following courses: Introductory Animal Nutrition, Feeds and Ration Formulation, Beef Cattle Science, and Feedlot Management. My research interests and accomplishments have included: 1) evaluation of fiber quality of forages and methods to enhance the digestibility of fibrous forages, 2) genetic factors associated with principle feed ingredients such as corn, corn silage and barley grain, and 3) characteristics of grain starch fermentability as affected by genetics and processing. Whereas my research program was very applied in nature it was fully integrated with teaching activities and my most significant contributions continue to be helping students acquire the skills needed to succeed in career positions. A less tangible contribution I have provided has been to provide our students with an abundance of relevant, outside-the-classroom learning experiences. Students enrolled in the degree programs in Animal and Veterinary Science have the opportunity to acquire vast technical knowledge complemented with applied understanding of animal agriculture and I am proud to be a part of their many successes.
Regardless of my appointment as a research and teaching faculty or as a department administrator, I have always felt it is my obligation and privilege to serve those who are engaged in animal agriculture throughout the state, region, and nation. I have a strong commitment to the three land-grant foundation missions of research, teaching and outreach. The Animal and Veterinary Department will strive to remain committed to those who are counting on us!


text:
Female , 16-17
Hi! I'm not your average teenager. I love Broadway and musicals of all kinds. I love my friends and family. Proudly a geek. Stick around for some of my life stories. Brian Sears thinks I'm brilliant. Rory O'Malley thanked me. So did Asmeret. And Nikki James. Kevin Duda thinks I'm awkward.
Last Seen Mar 7, 2013
Member Since May 03, 2012
Favorite Quote Life isn't about waiting for the storm to pass; it's about learning to dance in the rain.
- 100% Canadian
Horoscope Capricorn
Special day 3-24
Books Any.
Music Broadway, Great Big Sea, Mumford & Sons, anything indie/alternative. Oh and Rory O'Malley. And Andrew Rannells.
Movies Iron Man (BOTH!), Sherlock Holmes, HP, Star Wars, any musical.
Local Time July 29th, 3:25 AM
Think about me? Because you're constantly on my mind. I actually dreamt of you last night and I woke up happier than I have in a long time.So do you think about me? [more]
I Don't Care If Your Gay Or Straight Or BiHe's The Greatest. A friend of mine recently came out to me unintentionally. I asked him what was wrong via Tumblr, since he had posted that he wasn't feeling good. He went on to tell me that he had just b… [more]
I Am Never Going to Be Normal, Deal With ItHonestly? You want me to normal, be like everybody else. Do what they do, listen to their music, dress like them, be a regular girl who just follows the trends. Umm, how about hell no? … [more]
Yes, Of Course. I honestly believe that anyone who doesn't support gay rights has no respect for human beings in general. I mean, it's a personal choice, right? Personally, I'm straight but I know peopl… [more]
I Have A Friend Who Self HarmsDisbelief. I was sitting around at my house and I decided to go on Tumblr to see if any of my friends had it. So, by letting it look through my contacts on my iPod, it found a few. One of which was my good frien… [more]


text:
I grabbed this off the internet because Steve Colbert mentions the 110 birthday party of the light bulb.
Loading more stuff…
Hmm…it looks like things are taking a while to load. Try again?
TM + © 2015 Vimeo, LLC. All rights reserved.
Made with k in NYC.
Your content preferences apply to any Vimeo videos you view. Learn more about content preferences in our FAQ.


text:
Super Cute Sponsor – Oboro Charms
Posted on July 30th 2011 by Marceline in Super Cute Sponsors
Oboro Charms are one of our newest sponsors and make some of the most adorable little charms I have ever seen. Kim has just come out with a new Summer collection, which includes many of my favourite Summer things – I want a sandcastle!
You'll find all kinds of cute charms in the Oboro Charms shop though, including a whole parliament of baby owls, our favourite food with faces, and also some cute stickers and badges. If you've got something else in mind, Kim also takes custom orders so you can have your own personal charm.
More posts in Super Cute Sponsors
2 Responses to Super Cute Sponsor – Oboro Charms
July 31st, 2011 at 12:32 am
Oh!!! These are so, so cute! Critters and food and other cute things with faces–these are my favorite! :-)
August 8th, 2011 at 5:11 pm
They are very colorful!!Nice post here!!


text:
Gorella Back With Distaffers in Just a Game
"We chose this race because it's easier," said trainer Patrick Biancone, who also nominated Gorella to the Manhattan. "We ran her against colts last time because of two reasons. First, there was no money in the Distaff Turf Mile. Second, we wanted to see if she could go a mile and an eighth against top competition. She proved she could. We already know she is a top miler."Mirabilis is owned by Juddmonte Farms and trained by Bobby Frankel, who teamed up to win the Just a Game two years ago with Intercontinental. A filly by Lear Fan, Mirabilis easily defeated the ultra-consistent Wend in the Distaff Turf Mile five weeks ago. Wend is a multiple graded stakes winner on turf who simply did not fire on Kentucky Derby Day. She is likely to produce a better effort Saturday over a course on which she won the New York Handicap (gr. IIT). Wend goes out for trainer Bill Mott. $300,000 Just a Game Handicap (gr. IIT, Race 7, 3:50 p.m.), Fillies & Mares 3 & Up, 1 Mile (Turf)
PP. Horse, Weight, Jockey
1. Ozone Bere (FR), 116, Javier Castellano
2. Gorella (FR), 120, Julien Leparoux
3. Wend (KY), 119, Edgar Prado
4. Bright Abundance (KY), 115, Richard Migliore
5. Mirabilis (KY), 119, Garrett Gomez
6. Pommes Frites (KY), 116, Cornelio Velasquez
Copyright © 2015 The Blood-Horse, Inc. All Rights Reserved.


text:
How do I find out about Shwopping?
Shwopping is an initiative we've launched with Oxfam to help reduce unwanted clothing items going to landfill. You can donate your unwanted items in special Shwop Drop bins in our stores.
For further information see terms and conditions on marksandspencer.com. © 2015 Marks and Spencer plc


text:
Learn to use Adobe Illustrator and Photoshop to create realistic and beautiful aircraft profiles.
Discover how designers and engineers can share files between Illustrator and CAD programs like AutoCAD and SketchUp.
Learn how to use Illustrator to design clever, eye-catching packaging that holds up to the rigors of handling and satisfies your client's needs.
Reimagine your living room. Interior designers and homeowners alike can take advantage of Photoshop's tools to reconfigure a room.
Build a custom map for print or the web in Adobe Illustrator.
Helping you transition your skills from the print to the digital publishing world and select a format (from EPUB to iBooks) for your project.
"There are quite a few things that make lynda.com the best online learning platform. One of the greatest is that you guys listen and respond to your audience and I can't thank you enough for doing so." —Nathan
more from our members »


text:
August 4, 2015
Bryan's Fire Department is inviting the public to a Bagpipes and Drums performance this Sunday at 6 p.m. at Murphy's Law in Downtown Bryan.
Along with the performance, the fire department will also sell memorial t-shirts. The profits from the shirts will help the band travel to the Fallen Firefighter Memorial in Colorado Springs to honor Lieutenants Wallace and Pickard this September.
To comment, the following rules must be followed:
Comments may be monitored for inappropriate content, but the station is under no legal obligation to do so.
If you believe a comment violates the above rules, please use the Flagging Tool to alert a Moderator.
Flagging does not guarantee removal.
Multiple violations may result in account suspension.
Decisions to suspend or unsuspend accounts are made by Station Moderators.
Questions may be sent to firstname.lastname@example.com. Please provide detailed information.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.com.


text:
You have no items in your shopping cart.
Our Metallic Floral Lace is perfect for those projects that need a little bit of vintage style. The lace features a beautiful metallic large rose and leaf embroidery creating a fringe design. The metallic lace is very delicate and should be handled with care. Use this lace to add a fashionable accent to your garments and accessories. Try embellishing the waistline of a long evening gown or hemline of short cocktail dress. Available in metallic silver.
See Larger Image +
Get to Know M&J Trimming
Known worldwide for top quality trimmings and service.
Sign up for emails
Follow Us:
Our New York City Store
Customer Support
Helpful Tools


text:
Register now for free, or sign in with any of these services:
Want to set your local edition?
Select an edition for more focused local news coverage when you visit mlive.
Don't worry. You can change this setting at any time to another local edition.
I just keep getting a kick out of David's musings.
This country is so far in debt and democrats want to continue to spend like drunken sailors while looking for more folks to tax in order to pay for it.
It's high time we limited government to a % of GDP and made the prioritized decisions on what that money will be spent for.
That's why "everything" has to be on the table.
Both sides are hypocritically guilty of favoring their own spending while trying to cut spending favorites of the other side.
And folks like Kolb are still yammering about the war costs. If the political elites would just adopt the proper attitude towards war, it wouldn't cost so damn much. War is hell, let's go in like we mean business and get the job done.
This half assed approach of "winning the hearts and minds" is costing us lives and money. Hit it hard, hit it often and take no prisoners.
Then get out.
Yes David, everything has to be on the table, including the namby-pambyism we've watched unfold the last four years on capitol hill.
Instead of respect for rules policies and elders, we have a lot of parents willing t go to the mat for a kid who has screwed up.
The message? Damn the torpedoes, full speed ahead.
These kids should fear the parents consequences, but instead the parents back the kids against schools and authority. They send the WRONG messages.
Instead of protecting the kids from punishment and dissing the authority figures, they need to teach kids to abide by the rules.
I have friends who like to allow their kids to drink (under 18) and wink, wink, wink at the consequences of their consistent drunken states. Kids mimic parents.
Like John Cougar Mellencamp sang - I fight authority and authority always wins.
He's a beaut, Clark.
I'm sure both women were happy to have him at "the time".
Sometimes though when reality checks in, the truth comes home to roost.
All I can say is: What's next for this guy?
Bring it.
The airport and tourism department needs good, professional leadership.
Face it, the legislature screwed the pooch on this law. It was vaguely written and it set everyone up for a fall.
That being said, the potheads of the state have set out to abuse the law as best they could to exploit a weak statute that would allow them to toke legally.
Time to strengthen the law and make possession of very small amounts a misdemeanor and more a civil offense.
Let the police work on more serious crimes.
This is one Wiener of a column.
Wow. That must be a crazy, mixed up menagerie of thoughts in that mind, David. Inventing reality for yourself works in the mental ward, where others actually get paid to care for you. Oh wait, that's the reality you want for all of us. Uncle Sam paying lots of cash to take care of all of us. They call it "Obamacare" now.
Newsflash: Gingrich was never going to do anything but implode because his ego always leads him to bad judgement, which leads to bad decisions. Check his history. Brilliant man, flawed t the core.
And The Ryan plan isn't going out for recess because the Dems still control the Senate.
What are our choices?
Destroy entitlements or destroy our country with out of control government spending and deficits.
That made up reality world apparently cannot add up the fact that complete confiscation of all the money of the rich people and corporations would only last this country one year under the Obama budgets.
Somebody has to make some tough decisions. We know it won't be the candy-handing free spenders of the Obama administration.
Who will it be?
Stay tuned.
Snyder is getting is budget set up. There have been ZERO implications implemented thus far, but the naysayers are declaring the current system untouchable, and Snyders ideas a composite of "a race to the bottom", a "war on the middle class", and other phony statements because they have no solutions of their own.
They have parroted what we have had, which hasn't been working for some time (look at the evidence) and fear change is it impacts them in the very least.
Elections have consequences and the resulting policy and results will play themselves out. The unionistas have obviously hoisted up their skull and crossbones in an attempt to obfuscate and shout down real change under dubious claims .
This crap about the "wealthy" not paying their fair share is - just that. Crap. The top 5% pay a disprorportionate share of taxes and we are quickly approaching the point at which more than half pay no federal income taxes.
That is the equivalent of giving the kids the keys to the candy store.
And of course the handouts are very, very effective bribes to the recipients.
Its a prepaid ticket to government bankruptcy. The wealthy don't have enough to prepay a bankrupt system although there will be those who vote to make water from whine, and I see many of these kind of thinkers here.
While there a are lot of interesting comments relating to this topic, the theme is essentially liberal/unionista talking points.
The UAW and MEA have run this state for most of 50 years and many of the policies are practices are reminiscent of that control. The wage levels and benefits just need to be adjusted to reflect the realities in this country, which DO reflect on employment in this state.
All employers and jobs in this state will NOT reflect Walmart practices, that statement is a fallacy.
Remember A great number of those working at Walmart are there because their skill levels do not match higher paying jobs, not because all employers expect to lower everyone's wages. There ARE jobs though that LOTS of unskilled people need to take at lower wages, or the cost of living in this country would be astronomical.
The idea that everyone can make a LIVING wage is fallacy. Maybe it will exist someday, but the world economy prevents it from happening today or anytime in the near future.
Those that want to keep wages artificially high in this state will keep this state in decline by inflating the cost of doing business here.
The writer of this article probably also thinks it is good that were very almost at a point where 50% of the people in this country pay no income taxes, and the government knows better how to spend your earnings than you do.
There ARE lots of problems to talk about, but this legislation is going to make this state much more stable and create the right environment for Michigan going forward. It will make Michigan competitive with the rest of the country again and put us back on a growth path by rectifying some structural inequities in our economic system.
Watch and learn.
Under a rock?
Dropping numbers of pupils in districts are the funding issue in recent years.
If you look at the big picture, (last 20 years) education funding has increased dramatically and far exceeding results in student test scores or graduation rates.
Our issues in education are not related to the funds relegated to them. They are related to the waste inherent in public education.
We have built a house of cards.
There is still a ton of structural change, consolidation and cost savings to be realized from education. Preserving the status quo insures the incentive will not be there to make the necessary changes.
The teachers untenable benefits are one administrative and back office consolidation are others along with transportation.
Saying education cannot be cut is the MEA party line. Some money could be restored as tax revenues exceed budgeted projections, but not before.
When you elect incompetent politicians, someone has to come in and clean up the mess.
This country is headed in that direction. We are close to the point where more people are collecting benefits from the government than are paying taxes.
And of course, those folks will elect the candidate who promises to protect those on the dole, continuing the spending.
If you are a ward of the state, you are more of a fief and a thief than an informed voter.
Some folks elect incompetents and refuse to face reality.
And others just write letters because they are union activists and told to write and protest whether they understand all the facts or not.
No, the nation does not want Obamacare. And Romneycare is going to get skewered in the primaries.
The country needs a consumer driven healthcare system, not a federally controlled obamination like was passed.
That bill was a joke, a liberal pipe dream that will drive this country into default.
Nice funny, David. Romney "scoring points" for emphasizing Romneycare?
Romney 6-5 odds?
Romney will get tarred and feathered in the primary for his healthcare plan which is just as unpopular now as it was when passed.
Check in later when Tim Pawlenty and Mitch Daniels duke it out.
The ole' Huckster ain't getting in either.
After raising the US government spending to a modern day high and dwarfing Bush's spending habits (Which were very poor by the way)
Mr. "Hope and Change" is now Mr. "Defend the status Quo against mean/greedy/rich/evil/corrupt Republicans".
Try this on for size...
The only important products in the United States that do not get better and cheaper every year are K–12 education and health care, which are about 97 percent and 55 percent dominated by the government, respectively, and therefore have little consumer-price pressure.
What does Obama want to do with these programs? Expand them of course, and/or bring them under even more federal control.
Hows that Hopey/Changey thing workin' for ya?
Interesting. They told the Wright Brothers man could not fly.
They told the US man could not go to the moon.
So now a rural fire chief tells us there can be no improvements of any kind in public safety through consolidation?
Sounds more than a little self serving and uninformed to me.
There will be challenges, to be sure.
But I suggest someone give this man a drug test.
Whatever pipe he's been smoking must be causing semi-hallucinogenic thoughts.
Frankly Paula: your statements are definitely opposing. If residents of "like" concerns, interests and sentiments are grouped together for representation purposes to be more assured of appropriate representation, the reduction of the number of commissioners would more likely result in aggregation of dis-similar residents being grouped in a district and thereby involve an increase of the number of residents not being represented by a commissioner of their particular viewpoint.
Frankly, if interested folks took a look at the districts as they exist today, you will see significant gerrymandering. I have great distrust that anything good will come out of this next re-districting as it is dominated by the same folks that run the county board and hand pick their political appointees without regard to the interests of the county at large.
The most likely end result of such proceedings will be to assure current commissioners even "safer" districts than they currently come from. The commissioners elections should be non-partisan. As residents of the same community we should be able to elect those who we feel will make decisions that will better the local area rather than a political party.
There should be at minimum a "freeze" on the spending budget for this group, regardless of the final results.
Where was this hue and cry after the first three months of the Granholm regime? Three months and the sky has fallen?
Why my goodness it was in her re-election campaign that she stated we would be "blown away", but Steve - you are right in holding politicians accountable for their promises.
Jennifer said we would be "blown away" and by golly, she kept that campaign promise - to the "T".
The state has been struggling for a long time, and the electorate voted for a different direction. Let's allow it a tad more time, as the first budget has not been approved and 90 days has barely elapsed.
We know there will be pain. There is a constitutional requirement for a balanced budget in this state, and there is a hole in the upcoming budget forecast. Something must be trimmed.
Last I checked, unions are not hiring, unless they are using "stimulus" money. So where would those members become employed?
My guess would be businesses.
Let's talk after say - a year.
Then the tea leaves should start to show some evidence of whether we should have kept the status quo or moved to reinvent Michigan.
Personally, I've been "blown away" long enough to know that dog don't hunt.
While lots of politicians and enviros have "fallen in love" with wind, there is an economic side that is still not squared with the realities.
I'm not against wind, don't get me wrong, but how much are governments supposed to subsidize an "alternative" energy source before it becomes an economic millstone around the neck of the taxpaying public?
Consumers Energy prices its "green" energy at a ridiculous rate of return and the public is required to pay it, because we have "mandated" a percentage of green energy.
Here's a different perspective from the EU where they have adopted more wind than the US.
Zero factual societal harm was shown in this piece, merely an idea that somehow the high earners "might gain from others earning more" (no factual evidence presented) A suggestion that the income tax presented initially was a "tax on the wealthy". I think it had more to do with rasing revenue for the federal government's spending preferences.
This is a shadowy piece that merely infers something wrong with some folks being rich, or earning a lot of money.
What's next? inferring that the color of ones sin or their religion or nationality being somehow wrong?
Somehow some folks have it in their skull that diversity of income is bad, and that there must be some conspiratorial forces at work for that to be so.
They then see others that might benefit from more, and then to some wealth transfer scheme that they think will somehow make things better.
It's envy, and class warfare.
Show facts, empirical evidence and forecast provable overall economic gain.
Thus far, NOBODY has done so... this little piece included.
The ONLY shred folks reach for is raising taxes on the wealthy to improve the federal budget deficit.
But there isn't enough income, even at 100% confiscation to solve that problem.
We have a federal SPENDING problem. We spend FAR TOO MUCH. Until we get that under control, there is no tax system or income redistribution that will matter at all.
And this little socialist piece has left me stunned at it's lack of thought and research.


text:
The AV Box is a design that brings order to any environment. Crafted in California from solid maple wood, this versatile piece of furniture is built to fit your audio/visual components and last generations. Providing for a useful surface as well as simple storage, this beautifully crafted box—featuring dovetail joints and hand finishing—will add a luxurious element to the living room, and help to keep it tidy too.
Made from California Pacific Coast maple.
This product has no reviews yet. Be the first to review this product. Write a review
Enjoy 10% off your first order*


text:
Register now for free, or sign in with any of these services:
Want to set your local edition?
Select an edition for more focused local news coverage when you visit mlive.
Don't worry. You can change this setting at any time to another local edition.
Obama will need those borders open for the grand opportuity of yet another mass voter fraud
Again, where is our freedom of speech???? This is why I question Obama's stance on being a true and loyal American: he can't find himself to properly place his RIGHT hand over this LEFT (heart) side during the Pledge of Allegance and same goes for his wife.
Absolutely, repeal the whole thing. And when Taxholm and O'bama-lama-ding-dong raised taxes on cigarettes, they failed to learn from JFK who maintained that revenue does not increase with raised taxes!
Tax payers aren't reassured by Local, State or Federal Government!!
SORRY, Belay my Last
If as in Sacred Heart, you mean the Sacred Heart of Our Lord Jesus Christ, the it IS NOT WRONG!
The Holy Roman Catholic Church will NEVER be irrelevant...as Our Lord said: "Thou art Peter and upon this Rock, I will build My Church, and the gates of hell shall not prevail against it"
We're either going to follow this thing in Scripture, or we are, and if you don't then join a cult or something!
If as in Sacred Heart, you mean the Sacred Heart of Our Lord Jesus Christ, the it IS WRONG!
$27,228 extra, really? No wonder why local taxes are so high. Politicians and their support staff are public servants, but obviously we are working for them!
Well if he isn't anti-union, he should be! I'm tired of my tax dollars going to union support. We may have needed the unions at one time, but that time is about 70 years past! It's all about greed now! Greed that hurts consumers and taxpayers alike! The unions DON'T carry the country, the country CARRIES the union and it's high time for the free ride of OVER!
Better use a stun gun on a criminal trying to rob a store than a cop to use it on a teenager, who DIED!!!!!!!!!!!!!! Take the stun guns away from the cops!
Hey Snyder, don't act like the democrap Jennifer Taxholm! You just can't TAX MICHIGAN INTO PROSPERITY!!!!!!!
Brunner didn't do Bay City any good and is problem with Snyder would be????? He's a democrap, and these liberals would complain if you gave them a brand new rope to hang themselves with!
If Snyder is looking to China, perhaps because he knows that who the leading supporter of inflation in the United States is the friggin' unions!!!!
There is this union hall that was actually built by non-union workers. Yea, even the union morons know they're charging WAY too MUCH, for MEDOCRE work!!!
I actually crossed a picket like at CarQuest, because it was the RIGHT thing to do. I didn't buy anything, just stood up AGAINST the UNION JERKS!
How did they find out about who's working building O'Reilly's Auto Parts...seems as if the unions should mind their own ARROGANT business!!!
I actually crossed a picket like at CarQuest, because it was the RIGHT thing to do. I didn't buy anything, just stood up AGAINST the UNION JERKS!
How did they find out about who's working building O'Reilly's Auto Parts...seems as if the unions should mind their own ARROGANT business!!!
Hey, you union people, dig THIS: Non union people have to feed their families TOO! And they are NOT greedy. You union people are ruining the economy of this country by your GREED! Break up the UNIONS before they bankrupt the USA!!!
The Pledge of Allegiance isn't something that has to be voted on, you just do it as an American!
We wouldn't have to worry about buying ANYTHING made overseas, if the unions weren't ruining our economy by their greed!
Brunner is just a Democrat liberal, I really can't think of any other insulting words!
Let them smoke! We have bigger fish to fry!
All these states and local governments saying "WE'RE BROKE", guess what you bottom feeding suckerS of the public gravy trough, WE'RE BROKE TOO!!!!!!!!!!!!!!
It takes 4 weeks because this is more than likely being done by union workers who would absolutely make good dairy farmers..... THEY REALLY KNOW HOW TO MILK IT!!!!


text:
"We haven't been playing well," Coach Stan Heath said. "I'm not pleased with our cohesiveness or our sense of urgency. We have things we need to get fixed. We've lost five of six. I have the utmost respect
Day: March 15, 2005
Bracket Beefs
Who's got legitimate beefs:
Syracuse. A 4 seed for the Big East champs? That seems a little low, especially when the team they beat for the title got a 2. On the upside, though, I think everyone is
Larry Brown has surgery
A recent conversation between Larry Brown and his doctor...
Larry Brown: Doc, what does it mean, um... when fire shoot out your dick?
Doctor: Let me get this right, you're getting a burning sensation
Strahan told to stay away from his wife
I didn't know Strahan was Iking his wife (Definition: Iking; to Ike: verb. To abuse a spouse or significant other, verbally or physically. Word origin: The immortal Ike Turner.) Did I miss a news
Top 100 sports movie quotes
It's not that bad a list that ESPN.com's Page 3 put together. Chances are, I'd have probably had some issues with any list anyone put together. There's way too much Ace Ventura on this list, for example.


text:
Meeting Amenities
When you choose to host your event at the Radisson Blu Plaza Resort Phuket Panwa Beach, you'll enjoy access to a myriad of amenities and features. You can choose from on-site catering options to enhance meetings, social events and themed dinners, and the secretarial services and events team will work closely with you to meet all your needs.
Amenities include:
- Conference system
- Dedicated events team
- Digital signage in meeting room foyer
- Free high-speed, wireless Internet
- Full secretarial services
- Laptop rental
- LCD Projector
- Outstanding on-site catering
- Separate meeting entrance


text:
Pitta returns to practice, moves closer to lineup
Pitta on return: "I feel great"
Here's some good news for the Ravens. Dennis Pitta is back at practice. Which means his return to uniform is getting closer.
The Ravens announced Wednesday that Pitta would join them at practice for the first time since suffering his hip injury during training camp that required surgery. Judging from Pitta's comments, it did not sound like he would be ready to play Sunday against the Jets. However, with six games left to play, the Ravens (4-6) clearly hope to activate PItta off the injured-reserve, designated to return list at some point.
The Ravens (4-6) sorely need what Pitta brings to the tight end position. It's hard to quantify just how much the Ravens have missed him, but Pitta's absence has left a huge void. He caught 61 passes for 669 yards and seven touchdowns during the regular season, and he played superb football during the teams' Super Bowl run. Ravens receiver enjoys better chemistry with Joe Flacco. For now, Pitta is glad to rejoin his teammates on the field. And there was no doubt in his mind that he would be in uniform soon.
"I feel great, gonna take it slow though, make sure I can kind of integrate myself back in," Pitta said. "I had no setbacks in my rehab and treatment, and everything has been going well. We've been working hard. Excited to be able to get a little taste of football again."
[RELATED: Doss: "I just have to start making those plays" ]
Asked what barometer he would use to know when he was ready for games, Pitta said, "I gotta be able to play at an elite level. That's what it takes to play in this league. We'll see how the next few weeks go, and see how I progress, and how I'm doing on the field. Not sure, as of right now, of that timetable."
It has been months since Pitta has engaged in live contact on the field, so even Pitta was eager to see how his hip would respond to practice this week. "Things like that, you just can't simulate outside of the football field," Pitta said. "I'll do what I can, and take it slow, make sure we're smart about it and that I'm ready to go when that time comes."
Pitta is in the final year of his contract, but said that isn't factoring into his timetable to return.
"Obviously it's a part of this business, but I'm focused on helping our team win, and doing what I can to get back and contribute."
[RELATED: Search for consistent No. 2 receiver continues ]
Neither Dallas Clark (27 catches, 311 yards, three touchdowns) nor Ed Dickson (12 catches, 140 yards, on touchdowns) has filled the offensive vacuum left by Pitta.
"Versatility," said Dickson, describing what Pitta brings."With him out there, I mean he caught 61 passes last year. If he had gotten a chance to play this year, he might have caught more, the chemistry he has with Joe. He's a dynamic player."
Barring any setbacks, it appears the Ravens will add a key offensive weapon at some point down the stretch.


text:
The Screaming Females said they were embraced by the 'basement show' scene around New Jersey, where bands skip the clubs and play in people's basements.
- Filed Under
There's nothing pretty about Screaming Females, but "pretty" is kind of beside the point.
Eight years as a band, five full-length albums and a whole lot of shows later, this punk trio from New Jersey is more about energy than grace. "I don't want my song in a deodorant commercial," said Marissa Paternoster, whose caustic guitar gives Screaming Females its wired edge.
You'll find the band in the punk and indie sections of record stores, but beyond that, they're hard to categorize. "We never sat down and mulled over what kind of band we were going to be," Paternoster said. "We have lot of similar ...


text:
Venus Williams, who has an auto-immune disease called Sjogren's Syndrome, talks about her strict diet that's based on veggies and raw food. She also notes that she "cheats" from time to time, like the rest of us. Watch the video below:
Video: Venus Williams Diet Tips
June 2, 2012 by Leave a Comment


text:
Brothers formally charged in November double homicide
Prosecutors have filed formal charges against brothers Jacob and Nickolas Mislow, who are accused of shooting and killing two men during a botched drug deal in East Naples in November.
Subscribe to the Naples Daily News
Ready to subscribe to the Naples Daily News? Choose between a Premium or Digital subscription below.
Need Help? Call us at 1-888-878-6842.
Monday-Friday: 6am-6pm / Saturday: 7am-3pm / Sunday: 7am-2pm


text:
My Art and Craft Ideas Gallery
Welcome to my gallery page of art & craft ideas. Now let me begin by saying I use the term 'art' rather loosely, since I definitely do not consider myself a true artist. But I like to dabble and have fun and sometimes things just turn out especially nice:-)
Most of my craft projects are decorations I use in my home. I use lots of different materials: paper, wood, plaster, clay, twigs, chicken wire…… and on and on.
Oh and a special category are the craft projects where I use all kinds of threads: fabric, wool, old clothes, etc.
I also have a fondness for creating rather useless objects just for the fun of creating them. In those I usually use a variety of materials that I refer to all together as 'mixed media'.
Oh and definitely lets not forget my Christmas craft projects. The past years I have made most of my Christmas decorations myself. It is simply my favorite season to decorate and I strongly believe that homemade Christmas decorations are not only cheaper and more personal than store bought, they are also more fun.
I hope you have fun too, browsing through my collection of art and craft ideas.
General Craft Ideas
|Juju Hat Knockoff
|Cupcake Candle Holders
|Christmas Gift Wrap
|See all Craft Projects
Homemade Home Fashion
|Vintage Lampshade
|Sweater Pillows
|Number Pillows
|See all Home Fashion Projects
Mixed Media Art Ideas
|Hearts and Notepads
|Altered Match Boxes
|Gift Cards
|See all Mixed Media Projects
Christmas Craft Ideas
|Nativity Silhouette Lantern
|Pine cone garland
|Christmas Gift Wrap
|See all Christmas Craft Ideas


text:
Conservative activist Larry Klayman first rose to prominence suing the Clinton administration, but when Bush took office he proved himself an equal-opportunity lawsuit machine. ?It's not a left or right issue," says the self-proclaimed conservative libertarian, discussing his new book WHORES: Why and How I Came to Fight the Establishment. Klayman takes on the corporate media establishment and the legal and political systems, but is he really nonpartisan? Check out Laura's interview.
Laura Flanders talks to creative thinkers and change-makers from the worlds of politics, arts and the new economy. The smartest conversations, with the smartest thinkers and doers of our time, distributed in multiple formats on a variety of platforms. Keep abreast of fresh content by following GRITtv, the site Flanders founded, on Twitter @GRITtv.


text:
FeaturedProfiles.com is dedicated to our members' privacy. If a request for the input of personal data occurs on a page within FeaturedProfiles.com, the privacy policy will be available on the bottom bar. We currently only collect email addresses. Information gathered is protected by FeaturedProfiles.com with the utmost respect. Email addresses collected may be transferred and shared in the event of a sale of FeaturedProfiles.com or its owner, StockShark, LLC The email address is only used for email alerts from FeaturedProfiles.com.
DISCLAIMER & RISK DISCLOSURE: FeaturedProfiles.com and StockShark, LLC and our affiliates ("our companies") are not registered investment advisers or broker/dealers. Our companies make no commitment that the purchase of securities of companies profiled or otherwise mentioned in our websites are suitable or advisable for any person or that an investment in such securities will be profitable. In general, given the nature of the companies profiled and the possible lack of liquidity for their securities, investing in such securities is highly speculative and carries a high degree of risk. Never invest based solely on information from this Web site or our email alerts. Our FeaturedProfiles.com Newsletter is our free alert email membership. We profile selected companies on our site. These companies compensate StockShark, LLC for profile coverage. This compensation can be found in the disclosure on the bottom of the page of profiles. This Disclaimer & Risk Disclosure is also at the bottom of profiles. Specific questions on membership or profiles can be obtained by writing the FeaturedProfiles.com at: firstname.lastname@example.com.


text:
- Home
- News
- Sports
- Classifieds
- Obituaries
- Entertainment
- Special Sections
- Games
- June Real Estate Guide
- Summer Life in Whitley County
COLUMBIA CITY — An Ohio company with an office in Fort Wayne has agreed to assist Columbia City in prioritizing the removal of approximately 200 ash trees from the city's street right of way.
Davey Resource Group of Kent, Ohio sent a letter agreeing to help the town with the issue to Mayor Jim Fleck Nov. 24.
The Columbia City Board of Works and Safety agreed to the company's involvement with the project at the regular meeting on Friday.
In the letter, Project Manager Kasey Krouse said the company would "assist Columbia City in prioritizing the phased removal of all 200 ash trees located within the city street right of way."
Krouse said the removal of the ash trees are being done as a result of "emerald ash borers that has swept through northern Indiana killing hundreds of thousands of ash trees."
The company will prioritize the tree removal based on size, condition and location, the letter said.
The trees will be divided and then removed over a four-year period, approximately 50 trees per year.
The company will charge the city $55 per hour, including travel time. Krouse said the estimated time for the company to do the consulting work is 11 hours of field work plus an additional seven hours of data summarization.


text:
Thomas M. Archer, Ph.D.
4-H Agent, Shelby County
Doug Dill
4-H Agent, Champaign County
Eva M. Weber
4-H Agent, Lorain County
Sometimes meetings are very chaotic when making group decisions. Everyone talks at once, trying to sway others to a different point of view. A basic knowledge of parliamentary procedure can make the group decision process more orderly. It is an important skill youth can use throughout life. Parliamentary procedure is used by most groups as they conduct their meetings. A few examples where parliamentary procedure is practiced include Congress, county commissioners, school boards, local fair boards and county 4-H clubs and committees.
It is an organized method for a group to accomplish their goals in an effective, fair, and efficient manner. It is effective by providing an orderly way to conduct the group's business and make decisions. It is fair because it is a democratic process for making a decision. It is efficient by keeping the group focused. One item of business is disposed of before going on to another. Most parliamentary procedure is based on Robert's Rules of Order which describes procedures on how to conduct items of business.
4-H meetings are often the first exposure young people will have to parliamentary procedure. There are volumes of material written on the fine points of parliamentary procedure, but only the basics are necessary for 90% of the business conducted at a local 4-H club meeting. Start with the basics of parliamentary procedure in this fact sheet, then continue to "learn by doing".
One of the basics of parliamentary procedure is how to move and dispose of a motion. Here are the steps to follow:
There are times when members of the group will want to change the motion while it is in the discussion phase. This is called an amendment. It is recommended that only one amendment be permitted per motion. An amendment generally strikes out, adds, or substitutes words in the main motion. A motion has been moved and seconded and is being discussed. To amend a motion:
Tip: For less formal meetings, such as 4-H club meetings, it may be best to introduce complicated ideas by discussion before the motion is made. This eliminates the need for most amendments.
There are times when there is a reason to delay the decision on a motion. Perhaps there is not enough information to make a decision. The procedure to do this is called "laying on the table". This delays a decision until another time.
Tip: Generally, a tabled motion comes back for consideration at the next regular meeting. Don't use the motion to table as a way to "kill" a motion.
Adjournment is used to end the meeting.
A motion to adjourn can be given at any time during a meeting, but hopefully will not be misused by club members to adjourn prematurely when there is important business yet to be addressed.
Robert, Henry M. (1970). Robert's Rules of Order, Newly Revised, Scott, Foresman and Company, Glenview, IL, 1970.
National Association of Parliamentarians Web site http://www.filesource.com/parliamentarians/parlipro.htm.
All educational programs conducted by Ohio State University Extension are available to clientele on a nondiscriminatory basis without regard to race, color, creed, religion, sexual orientation, national origin, gender, age, disability or Vietnam-era veteran status.
Keith L. Smith, Associate Vice President for Ag. Adm. and Director, OSU Extension.
TDD No. 800-589-8292 (Ohio only) or 614-292-6181