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|These CD40 antigen deficient mice exhibit impaired immunoglobulin class switching and defective germinal center formation.
Former Names B6.129P2-Tnfrsf5tm1Kik/J (Changed: 30-SEP-05 ) Cd40 (Changed: 15-DEC-04 ) Type Congenic; Targeted Mutation; Additional information on Genetically Engineered and Mutant Mice. Visit our online Nomenclature tutorial. Additional information on Congenic nomenclature. Mating System Homozygote x Homozygote (Female x Male) 01-MAR-06 Species laboratory mouse Background Strain C57BL/6Ncr Donor Strain 129P2 via E14-1 ES cell line Generation N12F34 (10-NOV-08)
Generation Definitions
Donating Investigator Dr. Hitoshi Kikutani, Osaka University
Related Genotype: a/a
Mice homozygous for the targeted mutation are viable and fertile. Homozygous mutant mice are deficient of CD40 antigen and exhibit impaired immunoglobulin class switching. They mount an IgM response but no IgG, IgA, and IgE response to thymus-dependent antigens. However, IgG as well as IgM responses to thymus-independent antigens is normal. Germinal center formation is defective in mutant mice.
|Considerations for Choosing Controls
Strains carrying Cd40tm1Kik allele
002927 CNCr.129P2-Cd40tm1Kik/JView Strains carrying Cd40tm1Kik (1 strain)
View Related Disease (OMIM) TermsRelated Disease (OMIM) Terms provided by MGI
- Potential model based on gene homology relationships. Phenotypic similarity to the human disease has not been tested.Immunodeficiency with Hyper-Igm, Type 3; HIGM3 (CD40)
View Mammalian Phenotype TermsMammalian Phenotype Terms provided by MGIassigned by genotype
- hematopoietic system phenotype
- *normal* hematopoietic system phenotype
- normal thrombogenesis in ferric-chloride-induced injury of mesenteric arterioles (MGI Ref ID J:75152)
- decreased platelet aggregation
- reduced number of rolling platelets and 50% attenuation in platelet adhesion following 1 hour of middle cerebral artery occlusion and 4 hours of reperfusion (MGI Ref ID J:108988)
- immune system phenotype
- abnormal dendritic cell physiology
- increased susceptibility to bacterial infection
- homeostasis/metabolism phenotype
- decreased cerebral infarction size
- significantly reduced infarct volumes (MGI Ref ID J:108988)
- decreased platelet aggregation
- reduced number of rolling platelets and 50% attenuation in platelet adhesion following 1 hour of middle cerebral artery occlusion and 4 hours of reperfusion (MGI Ref ID J:108988)
- nervous system phenotype
- decreased cerebral infarction size
- significantly reduced infarct volumes (MGI Ref ID J:108988)
- skeleton phenotype
- decreased bone mineral density
- significantly reduced (MGI Ref ID J:145330)
- decreased compact bone mass
- significantly reduced (MGI Ref ID J:145330)
- decreased trabecular bone mass
- significantly reduced (MGI Ref ID J:145330)
The following phenotype information is associated with a similar, but not exact match to this JAX® Mice strain.
Cd40tm1Kik/Cd40tm1Kikinvolves: 129P2/OlaHsd * C57BL/6
- hematopoietic system phenotype
- absent spleen germinal center
- failed to form (MGI Ref ID J:25007)
- decreased immunoglobulin level
- decreased IgA level
- decreased IgE level
- decreased IgG1 level
- decreased IgG2a level
- decreased IgG2b level
- decreased IgG3 level
- decreased neutrophil cell number
- in non-SPF facilities compared to wild-type controls (MGI Ref ID J:25007)
- immune system phenotype
- *normal* immune system phenotype
- normal numbers and ratios of T and B cells (MGI Ref ID J:25007)
- abnormal humoral immune response (MGI Ref ID J:25007)
- decreased immunoglobulin level
- decreased IgA level
- decreased IgE level
- decreased IgG1 level
- decreased IgG2a level
- decreased IgG2b level
- decreased IgG3 level
- absent spleen germinal center
- failed to form (MGI Ref ID J:25007)
- decreased neutrophil cell number
- in non-SPF facilities compared to wild-type controls (MGI Ref ID J:25007)
- decreased susceptibility to type II hypersensitivity reaction
- in model of accelerated anti-glomerular basement membrane antibody-mediated glomerulonephritis (MGI Ref ID J:61673)
- deposition of IgG and complement in glomeruli not observed (MGI Ref ID J:61673)
- glomeruli almost normal (MGI Ref ID J:61673)
- fibrin deposition in glomeruli not observed (MGI Ref ID J:61673)
- failure to induce proteinuria (MGI Ref ID J:61673)View Research ApplicationsResearch ApplicationsThis mouse can be used to support research in many areas including:
Cd40tm1Kik related
Sensorineural Research
Cancer Research
Growth Factors/Receptors/Cytokines
Immunology, Inflammation and Autoimmunity Research
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Growth Factors/Receptors/Cytokines
|Allele Symbol
|Allele Name
|targeted mutation 1, Hitoshi Kikutani
|Allele Type
|Targeted (Null/Knockout)
|Common Name(s)
|CD40 Ko; CD40-; CD40KO; Tnfrsf5-; Tnfrsf5tm1Kik;
|Mutation Made By
|Dr. Hitoshi Kikutani, Osaka University
|Strain of Origin
|ES Cell Line Name
|ES Cell Line Strain
|Gene Symbol and Name
|Cd40, CD40 antigen
|Gene Common Name(s)
|AI326936; Bp50; CDW40; TNFRSF5; Tnfrsf5; expressed sequence AI326936; p50; tumor necrosis factor receptor superfamily, member 5;
|Molecular Note
|A neomycin cassette was inserted into exon 3. Disruption of the functionality of the protein was confirmed by a surface expression assay in spleen cells in which no binding of Tnfsf5 to ligand was observed. [MGI Ref ID J:25007]
Genotyping ProtocolsCd40tm1Kik, Standard PCR
Helpful LinksGenotyping resources and troubleshooting
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Vieyra M; Leisman S; Raedler H; Kwan WH; Yang M; Strainic MG; Medof ME; Heeger PS. 2011. Complement regulates CD4 T-cell help to CD8 T cells required for murine allograft rejection. Am J Pathol 179(2):766-74. [PubMed: 21704012] [MGI Ref ID J:174402]
Vitry MA; De Trez C; Goriely S; Dumoutier L; Akira S; Ryffel B; Carlier Y; Letesson JJ; Muraille E. 2012. Crucial role of gamma interferon-producing CD4+ Th1 cells but dispensable function of CD8+ T cell, B cell, Th2, and Th17 responses in the control of Brucella melitensis infection in mice. Infect Immun 80(12):4271-80. [PubMed: 23006848] [MGI Ref ID J:190620]
Vowinkel T; Anthoni C; Wood KC; Stokes KY; Russell J; Gray L; Bharwani S; Senninger N; Alexander JS; Krieglstein CF; Grisham MB; Granger DN. 2007. CD40-CD40 ligand mediates the recruitment of leukocytes and platelets in the inflamed murine colon. Gastroenterology 132(3):955-65. [PubMed: 17324402] [MGI Ref ID J:128219]
Vowinkel T; Wood KC; Stokes KY; Russell J; Krieglstein CF; Granger DN. 2006. Differential expression and regulation of murine CD40 in regional vascular beds. Am J Physiol Heart Circ Physiol 290(2):H631-9. [PubMed: 16172156] [MGI Ref ID J:106724]
Wakayama H; Hasegawa Y; Kawabe T; Hara T; Matsuo S; Mizuno M; Takai T; Kikutani H; Shimokata K. 2000. Abolition of anti-glomerular basement membrane antibody-mediated glomerulonephritis in FcRgamma-deficient mice. Eur J Immunol 30(4):1182-90. [PubMed: 10760808] [MGI Ref ID J:61673]
Wang X; Li H; Matte-Martone C; Cui W; Li N; Tan HS; Roopenian D; Shlomchik WD. 2011. Mechanisms of antigen presentation to T cells in murine graft-versus-host disease: cross-presentation and the appearance of cross-presentation. Blood 118(24):6426-37. [PubMed: 21963602] [MGI Ref ID J:179099]
White AJ; Withers DR; Parnell SM; Scott HS; Finke D; Lane PJ; Jenkinson EJ; Anderson G. 2008. Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input. Eur J Immunol 38(4):942-7. [PubMed: 18350550] [MGI Ref ID J:133775]
Wiesel M; Joller N; Ehlert AK; Crouse J; Sporri R; Bachmann MF; Oxenius A. 2010. Th cells act via two synergistic pathways to promote antiviral CD8+ T cell responses. J Immunol 185(9):5188-97. [PubMed: 20881183] [MGI Ref ID J:165190]
Willer DO; Speck SH. 2005. Establishment and maintenance of long-term murine gammaherpesvirus 68 latency in B cells in the absence of CD40. J Virol 79(5):2891-9. [PubMed: 15709008] [MGI Ref ID J:96699]
Williams JA; Zhang J; Jeon H; Nitta T; Ohigashi I; Klug D; Kruhlak MJ; Choudhury B; Sharrow SO; Granger L; Adams A; Eckhaus MA; Jenkinson SR; Richie ER; Gress RE; Takahama Y; Hodes RJ. 2014. Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways. J Immunol 192(2):630-40. [PubMed: 24337745] [MGI Ref ID J:207324]
Wong KL; Lew FC; MacAry PA; Kemeny DM. 2008. CD40L-expressing CD8 T cells prime CD8alpha(+) DC for IL-12p70 production. Eur J Immunol 38(8):2251-62. [PubMed: 18600823] [MGI Ref ID J:138592]
Wuthrich M; Fisette PL; Filutowicz HI; Klein BS. 2006. Differential requirements of T cell subsets for CD40 costimulation in immunity to Blastomyces dermatitidis. J Immunol 176(9):5538-47. [PubMed: 16622023] [MGI Ref ID J:131650]
Wykes M; MacPherson G. 2000. Dendritic cell-B-cell interaction: dendritic cells provide B cells with CD40-independent proliferation signals and CD40-dependent survival signals. Immunology 100(1):1-3. [PubMed: 10809952] [MGI Ref ID J:110408]
Yacoub D; Hachem A; Theoret JF; Gillis MA; Mourad W; Merhi Y. 2010. Enhanced levels of soluble CD40 ligand exacerbate platelet aggregation and thrombus formation through a CD40-dependent tumor necrosis factor receptor-associated factor-2/Rac1/p38 mitogen-activated protein kinase signaling pathway. Arterioscler Thromb Vasc Biol 30(12):2424-33. [PubMed: 21071692] [MGI Ref ID J:183202]
Yanaba K; Bouaziz JD; Matsushita T; Tsubata T; Tedder TF. 2009. The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. J Immunol 182(12):7459-72. [PubMed: 19494269] [MGI Ref ID J:149301]
Yasui T; Muraoka M; Takaoka-Shichijo Y; Ishida I; Takegahara N; Uchida J; Kumanogoh A; Suematsu S; Suzuki M; Kikutani H. 2002. Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals. Int Immunol 14(3):319-29. [PubMed: 11867568] [MGI Ref ID J:113575]
Yoshizaki A; Miyagaki T; DiLillo DJ; Matsushita T; Horikawa M; Kountikov EI; Spolski R; Poe JC; Leonard WJ; Tedder TF. 2012. Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions. Nature 491(7423):264-8. [PubMed: 23064231] [MGI Ref ID J:189218]
Zhao Y; Wilson D; Matthews S; Yap GS. 2007. Rapid elimination of Toxoplasma gondii by gamma interferon-primed mouse macrophages is independent of CD40 signaling. Infect Immun 75(10):4799-803. [PubMed: 17682046] [MGI Ref ID J:125278]
Zirlik A; Maier C; Gerdes N; MacFarlane L; Soosairajah J; Bavendiek U; Ahrens I; Ernst S; Bassler N; Missiou A; Patko Z; Aikawa M; Schonbeck U; Bode C; Libby P; Peter K. 2007. CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1. Circulation 115(12):1571-80. [PubMed: 17372166] [MGI Ref ID J:133045]
Animal Health ReportsRoom Number AX11
Colony Maintenance
Mating System Homozygote x Homozygote (Female x Male) 01-MAR-06 Diet Information LabDiet® 5K52/5K67
|Pricing for USA, Canada and Mexico shipping destinations
Price per mouse (US dollars $) Gender Genotypes Provided Individual Mouse $205.90 Female or Male Homozygous for Cd40tm1Kik
Price per Pair (US dollars $) Pair Genotype $411.80 Homozygous for Cd40tm1Kik x Homozygous for Cd40tm1Kik
Standard Supply
Repository-Live represents an exclusive set of over 1800 unique mouse models across a vast array of research areas. Breeding colonies provide mice for large and small orders and fluctuate in size depending on current research demand. If a strain is not immediately available, you will receive an estimated availability timeframe for your inquiry or order in 2-3 business days. Repository strains typically are delivered at 4 to 8 weeks of age. Requests for specific ages will be noted but not guaranteed and we do not accept age requests for breeder pairs. However, if cohorts of mice (5 or more of one gender) are needed at a specific age range for experiments, we will do our best to accommodate your age request.
|Pricing for International shipping destinations
Price per mouse (US dollars $) Gender Genotypes Provided Individual Mouse $267.70 Female or Male Homozygous for Cd40tm1Kik
Price per Pair (US dollars $) Pair Genotype $535.40 Homozygous for Cd40tm1Kik x Homozygous for Cd40tm1Kik
Standard Supply
Repository-Live represents an exclusive set of over 1800 unique mouse models across a vast array of research areas. Breeding colonies provide mice for large and small orders and fluctuate in size depending on current research demand. If a strain is not immediately available, you will receive an estimated availability timeframe for your inquiry or order in 2-3 business days. Repository strains typically are delivered at 4 to 8 weeks of age. Requests for specific ages will be noted but not guaranteed and we do not accept age requests for breeder pairs. However, if cohorts of mice (5 or more of one gender) are needed at a specific age range for experiments, we will do our best to accommodate your age request.
Repository-Live represents an exclusive set of over 1800 unique mouse models across a vast array of research areas. Breeding colonies provide mice for large and small orders and fluctuate in size depending on current research demand. If a strain is not immediately available, you will receive an estimated availability timeframe for your inquiry or order in 2-3 business days. Repository strains typically are delivered at 4 to 8 weeks of age. Requests for specific ages will be noted but not guaranteed and we do not accept age requests for breeder pairs. However, if cohorts of mice (5 or more of one gender) are needed at a specific age range for experiments, we will do our best to accommodate your age request.
|Considerations for Choosing Controls
|Control Pricing Information for Genetically Engineered Mutant Strains.
In case of dissatisfaction for a valid reason and claimed in writing by a purchaser within ninety (90) days of receipt of mice, products or services, JACKSON will, at its option, provide credit or replacement for the mice or product received or the services provided.
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Acceptance of delivery of MICE, PRODUCTS or services shall be deemed agreement to these terms and conditions. No purchase order or other document transmitted by purchaser or recipient that may modify the terms and conditions hereof, shall be in any way binding on JACKSON, and instead the terms and conditions set forth herein, including any special terms and conditions set forth separately, shall govern the sale of MICE, PRODUCTS or services by JACKSON.


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Melody Biringer
Self-avowed "start-up junkie," Melody has built companies that range from Biringer Farm, a family-run specialty food business to home furnishings to a fitness studio. Now she runs the CRAVEcompany, a network of companies designed to innovatively connect entrepreneurs who approach business in a fresh, new way with the stylish consumers they desire.
Monthly Archive for January, 2011
5 Reasons to Take More Risks in Your Business
Risk isn't about being careless or reckless. The risks you want to take are calculated risks. And while there is no guarantee even for calculated risks, if you're not willing to try something your business will stagnate. [Read More]
Why You Should Build a Business You "Know"
There is a famous adage that new writers should "Write what they know." The thinking being that your writing will be believable, authentic and that, when you have passion for a subject you know really well, it is much easier for the words to flow. [Read More]
Risk Taking: Should You Dare?
We're ringing in the new year at CRAVE with a question for all you women business owners out there… Do you dare? Is 2011 going to be a year of taking risks with your business, holding back, or a combination of both? [Read More]
Show More

subset: commoncrawl


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Below is the poem entitled The way... which was written by poet
Sackman. Please feel free to comment on this poem. However, please remember, PoetrySoup is a place of encouragement and growth.
Read Poems by
Shawn Sackman
The way your pajama bottoms don't match the tops
The way you exercise to ensure 'proper fitting pants'
The way our dogs wait for you to walk
The way our kids tease you just to hear you laugh
The way you keep on the move so you don't fall asleep
The way you do things for all of us, unasked
The way you take time to listen to a friend
The way you persevere when life sometimes makes you weary
It's all this and more that keep me …… well, it's just your way


text:
Home ⋅ Holiday & Christmas Birth Announcements ⋅ Christmas & Holiday Birth Announcements: Contemporary Collection ⋅ Studio Basics ⋅ $
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Get the latest on trends, deals and promotions
Leather Wrap BraceletBrought to you by Creativebug
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You don't have to be a chef or even experienced in the kitchen to decorate a cake, cookie, cupcake or brownie. The Wilton Method of Cake Decorating will teach you the techniques for making treats that will amaze your friends and family.
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Join us on an imaginary seven-week road trip from the beach to the county fair and beyond, with fun kids crafts at each stop. Registration starts April 25th and adventures begin in June.
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1) Schedule your Party 2) Pick a project 3) Celebrate the day!
We specialize in one-of-a-kind wishes and will create a party project just for your child.
Michaels makes your child's party easy, affordable and, most of all, fun!


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Sunday Link Love, Volume #172
Happy Sunday!
What have you been up to this weekend? Have you done anything fun or interesting? I can't say much in the way of interesting has happened this weekend, but it's been a nice weekend regardless! The weather is surprisingly warm for this time of year, so we took advantage of it yesterday by going for a long walk with Mellan. Today, playoffs, so we'll be watching a lot of football! I'll be getting through all of the comments and questions that are outstanding during the games, too.
- A fragrance that begins as a jasmine lover's dream [Kafkaesque]
- Some thoughts on the new MAC Huggable Lipcolours [Cafe Makeup]
- A look at the newest palette from Tarte [Musings of a Muse]
- Burberry's Primrose Hill Pink is a stunning shade [The Makeup Edition]
- Someone's in love with NARS' Adelaide Illuminator [Hello Jaa]
- A stunning shimmery bronze cream eyeshadow [The Beauty Look Book]
- Have you considered a coral lip with your smoky eye? [Weekend Ramblings]
Discussion and debate are highly encouraged, and we expect community members to participate respectfully. When asking a question, please check the FAQ section (above) for information about purchasing, price, dupes, and the like. If you have general feedback or need technical support, please contact us.
Comments that include advertisements, self-promotion, insults, etc. may be in violation of our comment policy and subject to deletion. Please see our comment policy for more information.


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- Musician's Friend Best Selection, Price & Service. Guaranteed.
Call our Gear Heads
at: 800-449-9128
Call our Gear Heads
at: 800-449-9128
Find a similar product below or contact our experts for a recommendation of great alternatives. Call us at 800-449-9128.Similar Items:
Find a similar product below or contact our experts for a recommendation of great alternatives. Call us at 800-449-9128.Similar Items:
The NAV8800 is a powerful, all-in-one loudspeaker controller, matrix mixer, and signal router.
The NAV8800 multi-function DSP unit from Sabine offers full control and fast setup of your audio production rig, easy configuration and secure installation of your commercial or worship sound system, and complete signal routing for multi-room venues--all with Sabine's superior DSP algorithms and robust hardware platform.
The NAV8800 is a complete 8 in/8 out digital system processor. 32-bit (40-bit extended) floating point processors and high-performance 24-bit digital converters represent the latest in signal processing technology.
Navigator Remote Control software provides a heads-up status display of all systems and fast access to all parameters. Equally powerful is the front panel control when you need full access at the rack position.
The FBX Feedback Exterminator is one of many innovations Sabine incorporated into the NAV8800. All DSP functions, including equalization, level control, delay, polarity, routing, multiple crossover selections, and gain management. Industry-standard Analog Devices SHARC processors handle the DSP processing.
Free firmware and software upgrades are easily done by connecting to Sabine's website. Keep your NAV8800 current with newly developed algorithms and functions. Flexible save and recall functions and complete system security round out this rugged unit.
Whether it's in a church, school, theater, or concert hall, your sound system is sure to benefit from the addition of the NAV8800. Call or click to order now.
Our product catalog varies by country due to manufacturer restrictions. If you change the Ship-To country, some or all of the items in your cart may not ship to the new destination.


text:
Gardener's Lifetime Cape Cod Weeder
Customers Also Bought
Exclusive | Traditional Cape Cod Weeder is the Best Tool for Tackling Tough Weeds
- Knife-like tool slices weeds and loosens crusted soil
- Forged steel blade is securely fastened into a comfortable hardwood handle
- Each tool comes with our exclusive lifetime guarantee
- Choice of right- or left-handed version
Used by generations of New England gardeners, Cape Cod Weeders slice weeds just below the soil line and are great for working in tight spaces. Our Gardener's Lifetime Cape Cod Weeder is hand-forged in Holland from the finest high-carbon Swedish boron steel with a pointed, self-sharpening tip. Unlike flimsy tools that are stamped from thin stainless steel, this weeder is ready for a lifetime of use by serious gardeners. To give it extra strength and durability, a 4" metal tang extends into the handle, which is securely fastened with a welded socket. The handle is made of sustainably grown European ash hardwood. Gardener's Lifetime Tools are handmade for us by a fourth-generation, family-owned business that has been crafting fine gardening tools for more than a century.
- Boron steel blade, FSC European ash wood handle
- 11-1/4" L overall
- Head is 3" L x 3/4" W
- Wooden grip is 4-1/2" L
- Hole in handle for hanging
- Lifetime guarantee
- Gardener's Supply Exclusive
REVIEW SNAPSHOT®by PowerReviews
- Effective (24)
- Easy to use (14)
- Long lasting (12)
- Eco-friendly (9)
- Safe (6)
- Inefficient (3)
Best Uses
- Weeds (28)
- Garden (19)
- Dandelions (11)
- Weeding (4)
- Lawn care (3)
- Reviewer Profile:
- Avid gardener (28), Getting started (5), Master gardener (3)
- Was this a gift?:
- No (18)
Reviewed by 57 customers
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Best Uses
Excellent help for pulling weeds from flower beds.
- Was this a gift?:
- No
- Indispensable
Best Uses
I use many tools for gardening: the large fork, the gardener's shovel, hand shovels, and clippers, but the very best tool for on-the-knees weeding and cleaning of my perennial garden is the Cape Cod weeder. It fits my hand well. The length is just right. The blade is strong and angled to loosen roots. I use it also to pull dead leaves from the base of small bushes. I have purchased two Cape Cod weeders as gifts for the gardeners in my family.
- Was this a gift?:
- No
- Well made
Best Uses
- Digging Out Sod
A friend showed me how useful this tool is and I ordered mine the same day. It works!
- Was this a gift?:
- No
Best Uses
I have three of these Cape Cod weeders, and this one is the best. Perfect weight, nice point on the blade, works perfectly
- Was this a gift?:
- No
Best Uses
Very sturdy and left-handed option a bonus.
- Was this a gift?:
- Yes
Best Uses
This was a replacement for a tool that my husband lost. The only thing I can figure out is it got tossed in with yard rubbish. I had used it for years and years. This one is the same as the one he lost - it is the perfect size for my hand and the perfect shape for digging under a weed to get it out, roots and all. Glad that Gardener's Supply carries it, was difficult to find it anywhere else.
- Was this a gift?:
- No
Best Uses
Great tool for weeding. Love that it's available in a left handed version!
- Was this a gift?:
- No
Best tool I've purchased for gardening. Would recommend and buy again. Used to weed between pavers and to provide leverage to pull up roots.
- Attractive
- Easy to use
- Great quality
- It Weeds
- Well-made
Best Uses
I use for weeding; i love how easy it is to handle.
- Was this a gift?:
- Yes
- Light
- Loosens The Dirt Well
- Very sharp blade
Best Uses
- Loosens Up Soil
- Weeding A Home Garden
I am always learning new tricks while I am gardening, and this is a Great one. I have a 10' x 15' plot in a Community Garden.
I have never minded weeding, it can be done in a meditative manner and be calming. However there are always many chores to get done so time does matter. Weeding with this tool goes amazingly fast. I work up the soil and it feels like the weeds cannot wait to come out. It keeps the soil nice and loose and my plants have all the room they need to grow.
- Was this a gift?:
- No
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There are no special shipping restrictions or charges associated with this item. For detailed information about our delivery methods and charges, click here.
We're proud of the fact that this item is shipped to you directly from our warehouse in Vermont, by one of our 250 employee-owners. In-stock items are packed with care and shipped within the next business day to ensure prompt delivery to your home and garden!


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"Do You Like Rock Music?" by British Sea Power (2008)
2012 Music Reviews
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"When it's done properly, sure"
British Sea Power's third full-length may sport the most gag-reflex prone title in recent memory but make no mistake, British Sea Power want to be your new favorite rock band and they've made an album full of arena ready barnstormers that will make everyone who hear it sit up and take notice. This may seem strange coming from a British band that up to this point have only a small cult following but that didn't stop a band like Snow Patrol a few years back now did it?
Personally I find it refreshing that a band like British Sea Power has stuck their necks out and gone for broke here on DYLRM. This is certainly their make or break release without a doubt and Rock Music will probably either mark them on their way to becoming "the next U2" alongside other contemporaries like The Arcade Fire or it will end them because this album will certainly disenchant most of their small Indie-Rock fan base who've enjoyed them as their own little secret. I'm hoping for the former, because other than that atrociously bad title, Rock Music is filled to the brim with excellent tracks that scream "turn it up to 11!" Lead vocalist Yan is still a dead ringer for Richard Butler of The Psychedelic Furs and tracks such as "Lights Out For Darker Skies" and "Waving Flags" certainly sound like auditions to be a Bono protégée. But don't sleep on BSP's other lead vocalist Hamilton. On tracks like "No Lucifer" (which is my favorite track he's sung so far period) Hamilton exudes a Robyn Hitchcock quality vocally that perfectly fits this new stadium sound that British Sea Power are diving head first into. Is there room on Rock radio and VH1 for bands that still sound like this? Who knows, but one thing is for sure, I'll be pulling for them all the way.
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text:
Giving a colourful boost to town's market
Last updated at 12:01, Thursday, 14 August 2014
NEARLY 2,000 people shopped at Whitehaven's second market festival, organised through the website, Visit Whitehaven.
Founder Luke Johnston, 16, said: "It was great to see so many people in the Market Place. We want to revive our historic town, and more people than ever turned up to support local businesses."
There was dancing from Stage Stars and singing from Cory Spedding.
Luke added: "It is important to put money back into the local economy. On Saturday there was something for everyone with many crafty stalls, food, jewellery and handmade gifts. This was reflected in the variety of ages who came into the town to shop."
First published at 11:51, Thursday, 14 August 2014
Published by http://www.whitehavennews.co.uk
Have your say
Lee, Great idea for the portaloos on the harbour. I have my own design business and would be more than happy to help you put some designs together to put forward to the Harbour Commision. If this is something you want to look into please add me on FB and then I can communicate my details more securely. Thanks Daniel Wroe LTD
The idea of Lee's Loos (sorry Lee) sound good, especially the portakabin. Perhaps the Harbour Commissioners could come up with some alternative designs that they think would be suitable, rather than just rejecting the idea. That would be a starting point to solving the problem.
View all 8 comments on this article


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Team.Net Mailing Lists
British Cars
MGs - For discussion about all models of MG Sports cars and sedans.
Triumphs - As above, but for Triumphs instead of MGs.
Healeys - Yes, you guessed it, a discussion list about Healeys, as in Austin-Healey, Jensen-Healey.
Pre-war (That's WWII) British cars.
Mini-Baja - Discussions about the SAE Mini Baja program. There's plenty more. Check out a web based
link. For those unfamiliar with how many mailing lists work, there is
To get more information about subscribing to any of the above lists, send mail to
with the word "help" in the body of the message.
Team.Net Automotive Information Archives


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Coaches Corner
Welcome to Coaches Corner, this is where basic skills and tips are described and outlined by the World's best Canoeing experts.
This area is not necessarily about becoming an elite athlete but gives all standards of paddlers the ability to gain valuable information regarding techniques in the sport of Canoeing.
What you find in the Coaches Corner could be in the form of an interview, video or an article including pictures, diagrams, or anything that can explain better the technical subject. The articles can be anything from different areas in training, technique, psychology, nutrition and any other relevant topics.
They will be added regularly across the spectrum of the sport (e.g. Canoe Slalom, Canoe Sprint, Canoe Polo etc).
Comments or tips can be sent to Heny Ahadpour at: email@example.com
ICF Canoe Sprint Coaching Manual
Download the ICF Canoe Sprint Coaching Manual Level 1 in PDF by clicking here. (right click and "Save as")
Coaches Corner articles
Coaches Corner Canoe Sprint Start
Coaches Corner Winter training
Coaches Corner Whitewater Mayhem Unravelled
Coaches Corner Psycological performance charactristic
Coaches Corner The term of load in canoeing
Coaches Corner Technical Development in the Winter Months
Coaches Corner The Transition Phase
Coaches Corner the YTP Mapping the Year to Peak Performance
Coaches Corner The price of Reaching the Canoeist Olympic Champion Title from the Aspect of a Coach
Coaches Corner The Three Ds Helping You Excel From One Competition to the Next (USOLYMPIC Coach Magazine/Fall 2012)


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Russia could acquire an in-flight refuelling version of the Il-96 in its 2006-15 procurement plan, says Ilyushin director general Viktor Livanov. "A feasibility plan for developing and manufacturing a tanker based on the Il-96-400T is being discussed. Technically, the development of the new tanker is not complicated, and there is a demand for increasing the Russian air force tanker fleet."
Russia's air force command has long been dissatisfied with its fleet size of just 20 Il-78/78M tankers used to support its Tupolev Tu-22M3, Tu-95MS and Tu-160 strategic bombers (Flight International, 4-10 January). It plans by 2010 to have sufficient aircraft available to support its upgraded Sukhoi Su-27SM fighters, which will be capable of in-flight refuelling.
Powered by four Perm PS-90A1 engines, the Il-96-400 meets international noise-abatement, pollution and flight-safety requirements and can be flown by two crew. But the development of an Il-96-based tanker is at a basic stage and financing remains unclear.
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03-18-2002, 10:57 PM #1Bryan Klakamp Guest
Repairing crack in knockdown ceiling
I have a hairline crack in a ceiling with knockdown texturing. What is the best way to repair it? Without redoing the rip joint, I thought about latex caulk in the crack, and then repainting. Good or bad idea?
03-22-2002, 08:50 PM #2Bob H Guest
Re: Repairing crack in knockdown ceiling
What's causing the crack?
03-23-2002, 07:22 PM #3Bryan Klakamp Guest
Re: Repairing crack in knockdown ceiling
I don't know what caused it. We used fiberglass mesh tape and 90 min. easy sand compound to set the tape and first coat. It's on a rip seam and is about 4' long. It is just a hairline crack, no compound has cracked out of it.
The house does shift from winter to summer. I assume that this is the reason for the crack. The homeowner is checking it over the winter and into spring to see if it changes at all. It very well may close up as warm weather gets here. The house is located in NW Ohio. It is in a sandy soil area.
Depending on what it does this summer, I wanted to use something that would give if needed.
Thanks for your help.
03-24-2002, 04:54 PM #4JohnNH Guest
Re: Repairing crack in knockdown ceiling
Bryan,I say it was the fiberglass tape,use paper next time.JohnNH
03-25-2002, 08:10 PM #5Myron Ferguson Guest
Re: Repairing crack in knockdown ceiling
I use paper tape on all my butt seams because it is stronger. For now caulk may work but it will look different when you paint it, so cover it with a thin layer of compound before painting. If you have to retape the seam it is not to hard to blend in a knockdown texture.


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Silver Screen Style // The Lost Boys
Posted on: Thursday, August 1, 2013
I remember being in elementary school and this girl I was friends with, Mallory, brought over a VHS of The Lost Boys and Creepshow. Because of that little slumber party, I will always associate those two movies with the end of summer — and Kiefer Sutherland as an 80s mullet-totin' vampire isn't so bad either, am I right?
1. Sonia Rykiel Ooh La La Tee // 2. Hawaiian Crop Top // 3. Tamou Camo Tee Shirt // 4. Superman iPhone 5 Case // 5. Turban Style Headwrap
1. UNIF Bad Kitty Rider Jacket // 2. Cropped White Tank // 3. Jeffrey Campbell Roscoe Boot // 4. Deborah Lippmann TrueBlood Nail and Lipstick Collection // 5. Bamboo 75 Biker Leather Pants
And for this, all you need is a wicked vampire hangover, a pair of shades, and an angst blood-sucking attitude.
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Amangiri provides guests with unrivalled levels of comfort and exceptional access to the region's geographic, historic and cultural marvels.
Amangiri is located in the southwest region of the USA also known as the Four Corners, where the states of Utah, Colorado, New Mexico and Arizona meet. Boasting one of the most dramatic landscapes in the USA with deep canyons and towering plateaus, the region has been home for centuries to the native Navajo and Hopi tribes yet is sparsely populated and presents the raw landscape for which the American Southwest has become famous.
The ecosystem surrounding Amangiri encompasses a remarkable diversity of plants and animal species with arid conditions supporting unique desert vegetation. Amangiri is in the centre of the Grand Circle, surrounded by such iconic attractions as the Grand Canyon, Monument Valley, Grand Staircase – Escalante and Bryce and Zion National Parks. It is also a safe haven for endangered species such as the regal California Condor, whose wingspan approaches three metres (ten feet). Historically, dinosaurs are known to have flourished in the region and footprints and fossils dating back 160 million years are common, with new species recently unearthed. Amidst these vast desert lands is Lake Powell, created in 1956 by the damming of the Colorado River at Glen Canyon. The lake sweeps through a seemingly endless stretch of canyons creating a shoreline longer than the Pacific Coast of the United States. To the south of the dam, the Colorado River runs through the Glen, Marble and Grand Canyons. The Four Corners region has a geographic diversity that is unrivalled, resulting in scenery as captivating as it is majestic.


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|Hyatt Hotels And Resorts Agra hotels are listed below. Search for cheap and discount Hyatt Hotels And Resorts hotel rooms in Agra, India for your group or personal travels. We list the best Hyatt Hotels And Resorts Agra lodging properties so you can review the Agra Hyatt Hotels And Resorts hotel list below to find the perfect place.
Our page will also list Agra, India hotels & motels that get similar quality scores of a Hyatt Hotels And Resorts.
Need 5+ Rooms? Lock in a group rate for Agra India
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Chanel Sari d'Eau Rouge Coco Shine
Chanel Rouge Coco Shine in Sari d'Eau
Chanel Sari d'Eau (44) Rouge Coco Shine ($32.00 for 0.10 oz.) is a semi-opaque orange with tangerine-gold shimmer and a glossy shine. It reads like a darker version of Sari Dore Rouge Coco.
It's actually more opaque than the Rouge Coco formula seems to be touted as, so while I will remove a point off of pigmentation for being too pigmented (I defer to what the brand claims the product should be), I wanted to make it a point to say as whether it's too pigmented for your liking (or maybe, just pigmented enough), may be a bigger deciding factor. It's not opaque like Rouge Allures, but everything I've heard from Chanel artists and read from Chanel pegs these as sheer to semi-sheer. I used about a layer and a half of product (just one pass around the outer edge of both lips, then a little dabbed on the center to ensure I had product everywhere).
It's a lightweight, nearly scent-free (I couldn't distinguish what it was, but it was very faint), and has an emollient base. It applies evenly and smoothly, because it has that balm-like quality. Unfortunately, it only lasts two to three hours on me, but I would say it is on the moisturizing side, though not as moisturizing as my favorite lip balms. I do wish these were the same size as other lipsticks in Chanel's line (like 0.12 oz.), because of the emollient base, it's easy to over-apply the product–and the need for reapplication being every couple of hours means you'll go through a tube much faster than other lipsticks in Chanel's range.
The Glossover
Sari d'Eau
|Sari d'Eau will work best with warmer skin tones, because it does pull very orange. There is, at most, only a hint of coral, but I find it's more like a crushed orange with lighter tangerine and gold shimmer.
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New ad campaign to promote SA's 'hidden jewels'
Locals asked to submit photos, places to visit on Facebook
SAN ANTONIO - "Remember the …" is the new ad campaign being launched in May by the San Antonio Convention and Visitors Bureau to promote "hidden jewels" known most to locals, but seldom experienced or seen by out of town visitors.
"What this is going to do is give us the opportunity to share those stories and memories of San Antonio that makes it so special," said Casandra Matej, CVB executive director.
Matej said CVB is taking its popular "Deep in the Heart" campaign to the next level by asking locals to submit photos to the CVB page on Facebook.
By doing so, Matej said the new national campaign is meant "to embrace the authenticity of people's memories, what people want to share about their own city."
She said those who take part will be eligible for a social media sweepstakes where winners will be selected at random for prizes such as vacation packages and Spurs tickets.
Matej said the first contest will run through May 7, with at least a dozen additional other sweepstakes planned for the remainder of the year that will focus on tourism categories such as cuisine, arts and culture and family activities.
Many tourists on the River Walk said they are eager to find other places to see that are off the beaten path.
"We've been on the mission tour but other than that, I don't know where else to go," said a visitor from Houston.
A group of tourists from Chicago and Nevada said they suggest "old things that would show old San Antonio" or "music, music, we all love music."
One of the visitors said, "We like it here but we've kind of been here and done the same things every time that we've come."
Copyright 2012 by KSAT.com All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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All Evidence Points To Bombings Being Staged
April 28th, 2013
April 28th, 2013
(AJC) – It took a while but the Feds finally came clean to having prior knowledge of deceased bombing suspect Tamerlan Tsarnaev. They also had his mother on a terrorist watch list.
No related posts.
Tags: alex jones, bombing staged, evidence
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