text:
Chewable medicament tablets are made from coated granules of a medicament wherein the coating on said granules comprises a blend of cellulose actate and/or cellulose acetate butyrate and hydroxypropyl cellulose and a process for making such tablets and a method of providing sustained release of medicaments utilizing such coated granules in a tablet.
1. A chewable tablet of a medicament comprising compressed coated granules, said coated granules individually comprising medicament coated with from about 5 to about 28% of the total dry weight of the coated medicament granule of a polymer blend of: (a) cellulose acetate, cellulose acetate butyrate and combinations thereof; and (b) hydroxypropyl cellulose wherein the ratio of cellulose acetate, cellulose acetate butyrate and combinations thereof to hydroxypropyl cellulose is in the range of about 97/3 to about 50/50.
2. The chewable tablet of claim 1 wherein the medicament is selected from the group consisting of ibuprofen, acetaminophen, aspirin, naproxen, pseudoephedrine, dextromethorphan, chlorpheniramine, loperamide, diphenhydramine, famotidine, cimetidine, ranitidine, nizatidine, salts thereof, and combinations thereof.
3. The chewable tablet of claim 1 wherein the polymer blend is intended for sustained release and contains from about 3 to about 15 weight percent of hydroxypropyl cellulose.
4. The chewable tablet of claim 1 wherein the coated granules are intended for sustained release and contain from about 16 to about 28 percent of said polymer blend.
5. The chewable tablet of claim 1 wherein the coated granules are intended for taste mask and contain from about 8 to about 15 weight percent of the polymer blend.
6. The chewable tablet of claim 1 wherein the medicament comprises ibuprofen.
7. The chewable tablet of claim 1 wherein the medicament comprises dexibuprofen lysine.
8. The chewable table of claim 1 wherein the medicament comprises ibuprofen.
9. The chewable table of claim 1 wherein the medicament comprises a combination of ibuprofen and pseudoephedrine.
10. The chewable table of claim 1 wherein the medicament comprises loperamide.
11. The chewable tablet of claim 1 wherein the medicament comprises acetaminophen and diphenhydramine hydrochloride or citrate.
12. The chewable tablet of claim 1 wherein the medicament comprises a combination of acetaminophen, pseudoephedrine, dextromethorphan and chlorpheniramine.
13. The chewable tablet of claim 1 wherein the medicament is a combination of an analgesic selected from the group consisting of ibuprofen, acetaminophen and aspirin; with pseudoephedrine; chlorpheniramine, and dextromethorphan.
14. A process of preparing a chewable medicament tablet comprising the steps of:
coating medicament granules with from about 5 to about 28% of the total dry weight of the coated medicament granule with a polymer blend of cellulose acetate, cellulose acetate butyrate or a combination thereof and hydroxypropyl cellulose wherein the ratio of cellulose acetate, cellulose acetate butyrate and combinations thereof to hydroxypropyl cellulose is in the range of about 97/3 to about 50/50; and forming a chewable tablet by compressing the coated medicament in the presence of excipients.
15. A method for taste masking medicaments comprising coating a medicament composition with a taste masking effective amount of a polymer blend of cellulose acetate, cellulose acetate butyrate, or combination thereof and hydroxypropyl cellulose.
16. The method of claim 15 wherein the medicament coated is selected from the group consisting of ibuprofen, aspirin, naproxen, acetaminophen, loperamide, pseudoephedrine, dextromethorphan, chlorpheniramine, diphenhydramine, famotidine, cimetidine, ranitidine, nizatidine, salts thereof, and mixtures thereof.
17. The method of claim 15 wherein the medicament is dexibuprofen lysine.
18. A method of providing sustained release of a medicament comprising coating a medicament with a sustained release effective amount of a polymer blend of cellulose acetate, cellulose acetate butyrate or combination thereof and hydroxypropyl cellulose.
19. The method of claim 18 wherein the medicament is selected from the group consisting of ibuprofen, aspirin, naproxen, acetaminophen, loperamide, pseudoephedrine, dextromethorphan, chlorpheniramine, diphenhydramine, famotidine, cimetidine, ranitidine, nizatidine, salts thereof, and mixtures thereof.
This invention relates to tablets containing means to mask the taste of active ingredients and/or provide sustained release of such ingredients. More particularly, the means of providing taste masking and/or sustained release of active ingredients are coatings comprising blends of hydroxypropyl cellulose with cellulose acetate and/or cellulose acetate butyrate.
Orally administered medicaments are given to the patient in many forms, such as liquid solutions, emulsions, or suspensions, or in solid form such as capsules or tablets (as used herein, the term "tablet" means any shaped and compressed solid dosage form, including caplets). Medicaments administered in tablet or capsule form are usually intended to be swallowed whole. Therefore, the often disagreeable taste of the active ingredient need not be taken into account in formulating the medicine, except for the provision of means to prevent the taste from being apparent during the short time that the medicine is in the mouth. Such means may include the provision of an appropriately thin and quickly dissolving coating on the tablet, the use of the gelatin capsule form (the gelatin outer shell of the capsule keeps the active ingredient inside until the capsule has been swallowed), or simply compressing a tablet firmly so that it will not begin to disintegrate during the short time that it is intended to be in the mouth.
Children, older persons, and many other persons have trouble swallowing whole tablets and even capsules. Therefore, in cases where the dosage to be administered cannot be made into a very small tablet or capsule, it is desirable to provide the medicine either in liquid form or in a chewable solid form, in addition to the tablet or capsule that is designed to be swallowed whole. Even where the medicine can be formulated as a liquid, it is desirable also to be able to provide a chewable solid form because it is usually more convenient to carry a supply of tablets with oneself all day than a container of liquid medicine.
A common problem with chewable tablet forms is the often disagreeable taste of the active ingredient which manifests itself during chewing. In some cases, the taste of the active medicament in a tablet can be overpowered by adding flavoring ingredients to the tablet so that when it is chewed the taste of the active ingredient is simply overpowered. For instance, this has been done with children's aspirin where the dosage is small enough so that the amount of flavoring agents needed to mask the taste of the medicine is not so great that the tablet becomes unreasonably large. A children's size tablet of acetaminophen (acetyl para-aminophenol or "APAP") is available commercially wherein the APAP is present in, granules that are coated with ethyl cellulose. A significant proportion of the APAP remains shielded by the coating (and therefore does not contribute to taste) while the tablet is in the mouth, despite some breakage of the ethyl cellulose coating during compression of the tablet and some additional breakage of the coating during chewing. The APAP becomes bioavailable via permeation through the coating (although ethyl cellulose is not soluble in aqueous fluids, water does permeate through the coating) and from the granules wherein the coating was broken.
Co-pending U.S. Pat. application Ser. No. 214,265 filed June 30, 1988 as a continuation-in-part application of Ser. No. 121,692 filed Nov. 16, 1987, now abandoned, by Thomas N. Julian and Galen W. Radebaugh discloses chewable medicament tablets wherein the granules of active ingredient are coated with a blend of cellulose acetate or cellulose acetate butyrate and polyvinyl pyrrolidone (PVP).
The present invention is directed to the discovery of a coating that can be used to coat granules of active medicament and which can achieve a better balance between taste masking and control of bioavailability than can be achieved with ethyl cellulose or other previously known combinations. Further, the coating of the invention can provide a sustained release coating for medicaments.
As embodied and fully described herein the present invention provides a medicament coating comprising a blend of cellulose acetate (CA) and/or cellulose acetate butyrate (CAB) and hydroxypropyl cellulose (HPC). The coating provides excellent taste masking while still permitting acceptable bioavailability of the active ingredient. Further, the coating can provide for sustained release of the medicament.
In preferred embodiments of the invention the coated medicament is included in a chewable tablet comprising compressed individual particles of medicament particles coated with a blend of CA and/or CAB and HPC.
In further preferred embodiments, ibuprofen particles are coated with a blend of CA and/or CAB and HPC and are then compressed into tablet form together with flavoring agents and other ingredients that are customarily used in making such chewable tablets.
The invention also provides a process of making and methods using the chewable tablets, as well as, a method of using the coated medicament particles for sustained release of the active ingredients.
The invention will now be described specifically in terms of its most preferred embodiments which is the preparation of chewable tablets of ibuprofen, a medicament used in both over-the-counter preparations and in prescription drugs for analgesic and antipyretic purposes. Reference will also be made in detail herein to other preferred embodiments of the compositions, processes and methods of the invention.
In the preferred embodiment of the process of the invention, medicament, preferably ibuprofen in granular form, is coated with a blend of HPC and CA and/or CAB so that the granules are coated with the polymer blend. The coated granules, together with other ingredients such as flavoring agents, extenders, exipients, and the like, are compressed into tablet form. (As used herein, the term "granule" refers to individual particles or to agglomerates of individual Particles of the medicament.) A high enough proportion of the coating remains effectively intact on the ibuprofen granules through the compression of the tablet and through normal chewing in the mouth to permit effective taste masking of the normally bitter tasting ibuprofen. The term "effectively intact" means that the coating remains sufficiently integral to mask the taste or flavor of the medicament detectable through the coating. This taste masking provides a mean to limit the quantity of other flavoring agents in the tablet is not be so large that an excessively large tablet is required to overpower rather than mask the unpleasant flavor of the medicament.
When the coated granules are swallowed, the active medicament becomes bioavailable via permeation through the coating. Permeation can occur through the intact coating as well as through the coating that has become porous through dissolution of the water soluble HPC component of the coating; the CA and CAB components are water insoluble. Permeation also occurs via disintegration of the coating, which is caused in part by chewing, in part by processing of the tablet (compression), and in part by removal of the HPC component of the coating by dissolution.
The coating may be designed so that the medicament is released relatively rapidly or in a sustained release mode, depending on the proportion of coating to medicament in the granules, or the proportion of the CA and/or CAB to HPC in the coating, or their combination. Generally, higher proportions of HPC used in the coating leads to more rapid release of the medicament.
Cellulose acetate and cellulose acetate butyrate are quite water insoluble but are soluble in organic solvents. They can provide good taste masking properties since they do not dissolve in the mouth and are tough enough to remain effectively intact during processing and normal chewing in the mouth. If used alone, however, a coating of CA and/or CAB would not provide adequate bioavailability of the active ingredient after swallowing the chewed tablet. To provide the requisite bioavailability, HPC is added. HPC is a polymer which is soluble in both water and organic solvents. The water solubility of HPC provides the bioavailability of the active medicament in the GI tract via the mechanisms discussed above. The solubility of HPC in organic solvents permits ready mixing with CA or CAB during the production of the coated granules, since CA and CAB are not very soluble, if at all, in water, and are most conveniently applied from an organic solvent solution. HPC and CA and/or CAB form clear compatible solutions in organic solvents, preferably acetone/methanol mixtures, which are suitable for pharmaceutical coating. The blend of CA and/or CAB and HPC provides the balance needed for good taste masking while being chewed in the mouth, along with either rapid or sustained bioavailability of the active medicament in the GI tract after swallowing.
The HPC and CA and/or CAB blends of the invention have been found to be more versatile than the PVP blends of Julian and Radebaugh discussed earlier. Due to the superior flexibility of HPC polymer as compared to PVP, higher percentages of HPC (up to 50%) can be used than is recommended by Julian and Radebaugh for PVP (3 to 30%). Higher amounts of the water soluble component HPC increases the rate and extent of disintegration of the coating thus increasing the porosity of the coating. Presence of such higher amount of the water soluble component HPC advantageously increases the bioavailability of the coated medicaments.
The coating used is preferably a blend containing about 50 to about 97 percent of CA and/or CAB, by weight of the coating, and about 3 to about 50 percent HPC. Within the range indicated, if sustained release of the medicament is desired, a lower proportion of the water soluble HPC may be used. When rapid release of the medicament is desired, a higher proportion of the water soluble HPC is used, i.e. up to 50 percent. Routine experimentation will suffice to determine the appropriate proportions of the two polymers to use in individual cases, as is more specifically illustrated below. The upper limit of about 50 percent HPC is limited by practical processing considerations. The tackiness of the coating solution increases in the higher range amounts of HPC and amounts over 50 percent may lead to particle agglomeration during the coating process. Further, the rate of release can be controlled by use of HPC of specific molecular weight, whereby, higher molecular weight HPC leads to a slower release of medicament.
The coated granules may be made by coating the granules of medicament with an organic solvent solution of the polymers in a fluidized bed coating operation. A wide variety of organic solvents may be used to prepare the organic solvent solution of the coating polymers. For instance, a preferred solvent is acetone-methanol, but other solvent systems may also be used, including methylene chloride-methanol (e.g. 9:1), acetone-ethyl acetate, toluene-ethanol, and others. As a general rule, the proportion of polymer in the solvent solution will be from about 5 to 20 and preferably 8 to 15 weight percent for optimal taste masking and rapid release of drug depending upon the specific solvents used and other similar considerations.
The polymers are dissolved in the solvent and the polymer solution is then coated onto ibuprofen or other medicament active ingredient or combination of ingredients granules, using a fluidized bed coater. Air (which may be heated) passes through a bed of the medicament granules to fluidize them, and the solvent solution of the two polymers is sprayed onto the fluidized bed and thereby coats the granules. The air passing through the bed dries the coated granules, so that a dry coated granule is obtained. The coated granules are then used in combination with various excipients, flavors, and colors to make a chewable tablet.
The dried coating as thus applied usually constitutes about 5-28 % of the total dry weight of the coated ibuprofen granule. The exact proportions of coating to medicament desired for individual cases can be determined by routine experimentation. The amount of coating may be varied in light of the intended application and desired bulk of the products. Chewable tablets can be acceptable in larger sizes than swallowed tablets since chewing will reduce the size of the tablets in the mouth. Further, tablets intended for pediatric use generally comprise reduced dosage amounts and less bulk. Larger proportions of coating may be used to provide a sustained release or better taste formulation.
When two or more medicaments are utilized in a tablet the coatings may be varied to provide a slower release of one medicament over another. This is especially advantageous for dosing a combination of medicaments that are more effectively released in different parts of the digestive tract or are better released separately in the digestive tract to avoid interference with each other or other incompatibility. Further, the same medicament may be subject to different coating composition and amounts to provide for sustained release of some portion of the medicament and immediate release of another portion of the medicament to achieve an optimal dosing versus time profile. Obtaining such optimal dosing/time profiles depends upon the particular medicaments and medical needs required. The exact proportions of coating materials used to achieve these profiles can be determined by routine experimentation.
While exact size of the coated granules has not been found to be critical, the coated granules will usually be sized to pass between between about a 10 and 200 mesh sieve screen (U. S. Sieve Series). In the usual case, the coated granules will be sized from about 40 to 60 mesh.
In addition to ibuprofen, any solid medication in need of taste masking can be used in the invention. Illustrative examples include aspirin, naproxen, acetaminophen, pseudoephedrine, substantially pure dexibuprofen (i.e. less than 20% of the inactive R-antipode), dexibuprofen lysine, cimetidine, ranitidine, nizatidine, psuedoephedrine hydrochloride, chlorpheniramine maleate, dextromethorphan hydrobromide, diphenhydramine hydrochloride or citrate, dextromethorphan, chlorpheniramine, loperimide, simethicone, salts thereof and combinations thereof. Identification of medicaments herein is intended to apply to pharmaceutically acceptable salts thereof as well. Further, the coating of the invention provides a convenient means for providing sustained release of medicaments and for presenting a viable dosage form for combination medicaments which are incompatible before (during storage) or after administration or for medicaments which are desirably released in the GI tract at various times or in various places thereof.
The following procedure and Examples provide examples of preferred method and materials for practicing the present invention. These Examples should be considered illustrative only and not limitative of the present invention.
An illustrative preferred procedure for preparing the coated granules of medicament in accordance with the invention is the following:
A solution of the coating polymers is prepared in an organic solvent by simply adding the polymers to the solvent with stirring. The medicament, in granular form, is placed in a fluidized bed coater and is fluidized by a flow of warm air. The temperature of the air has not been found to be narrowly critical, and can vary over a wide range, keeping in mind the fact that the temperature should not be high enough to cause decomposition, sintering, or melting of the medicament granules. When coating ibuprofen granules, a temperature of from about 55� to 75� C. is suitable but such temperature ranges will change depending on the medicament being coated. The rate of air flow is adjusted so as to fluidize the granules. Such flow will vary depending on factors such as the specific equipment used, the size of the charge of granules, the size of the individual granules, the apparent specific gravity of the granules, and other factors that are known to the worker in the arts relating to fluidized bed coating.
After the medicament has been fluidized, the polymer solution is sprayed on top of the fluidized bed. The air flow through the bed is continued until the amount of solvent remaining in the coating has been reduced to parts per million levels. The granules are actually dry to the touch within a very short time after the coating solution has been sprayed onto the granules of medicament; a matter of a few seconds in some cases. However, the total drying time required to ensure that the organic solvent content of the coating has been reduced to the level desired may take much longer, depending on the temperature of the air, the size of the batch, and the like. For batches of ibuprofen weighing four to six kilograms, total drying times of the order of one to three hours have been used. Routine experimentation will suffice to determine the appropriate air temperatures and total times required in the fluidized bed coaters in individual cases.
The Examples below set forth the ingredients and proportions for typical laboratory scale preparations of coated medicament granules. The materials used are the following:
Ibuprofen--In the form of granules having a particle size of about 60 mesh;
Loperamide (HCl salt)--In the form of granules having a particle size of about 40-80 mesh;
APAP--Acetaminophen USP granules having a particle size of about 170-270 microns;
Famotidine--In the form of granules having a particle size of about 170-270 microns;
Dexibuprofen lysine--substantially pure granules of S-ibuprofen lysine salt with less than 20 and preferably less than 10% of the inactive R-ibuprofen antipode present.
CA--Cellulose acetate NF powder, for example, CA 398-10 or CA-320S available from the Food and Pharmaceutical Products Division of FMC may be used. The CA 398-10 polymer has an acetyl content of about 39.8%, by weight, a hydroxyl content of 3.4%, by weight, a degree of substitution of 2.7, and a solution viscosity of about 38 poises or 10 seconds, determined by ASTM Method D 1343 in the solution described as Formula A, ASTM Method D 871. According to the manufacturer, the typical weight average molecular weight is 177,000 and the typical number average molecular weight is 58,500. The CA-320-S polymer has an acetyl content of about 32.0%, by weight, a hydroxyl content of about 9.0%, by weight, and a degree of substitution of 2.1. The manufacturer reports a solution viscosity in 90:10 CH2 Cl2 :methanol, at 4% (w/w) concentration, of 50 cps. Typical weight average molecular weight is 100,500 and typical number average molecular weight is 63,500, according to the manufacturer. (Viscosities in poises are converted to ASTM seconds equivalent to values obtained under ASTM Method D 871.);
CAT--Cellulose triacetate powder, CA-435-75S is also available from FMC. This CAT's acetyl content is 43.5 and the solution viscosity is 68 seconds, determined by the "Ball Drop Method" of ASTM D 1343, using the solution designated "Formula D" in Table 2 of ASTM D 871;
CAB--Cellulose acetate butyrate, CAB 171-15S from FMC. The polymer has a butyryl content of 17 weight percent, an acetyl content of 29.5 weight percent, and a viscosity of 24 cps in a 4 weight percent solution in methylene chloride:methanol (90:10) one day after solution preparation. The viscosity is taken at about 25� C.;
HPC--Hydroxypropyl cellulose having a molecular weight of about 80,000 to about 370,000. Suitable HPC includes those available from Aqualon in the grades known by the tradenames KLUCEL EF, LF, JF or GF.
The term "total coat" refers to the proportion of coating to medicament in the coated granule product, "charge" to the weight of medicament, "polymer solution" to the proportion of polymer in the organic solvent solution, and "total batch" to the weight of medicament plus coating.
Examples I-X, below, display the identity of medicament(s), coating polymers, organic solvents and organic solvent solutions of coating polymers, and the proportions of all of these materials for typical laboratory scale batches of coated medicament granules for use in the invention in accordance with the preferred procedure for preparing coated granules of medicament as described above.
Form of Active--Granular APAP with particle size of 170-270 microns.
Coating Solution--Cellulose Acetate 398-10/ Klucel LF in Acetone/Methanol 80/20 at 8-12% solids.
Note: Klucel LF has a weight average molecular weight of 95,000. Klucel EF (Molecular Weight 80,000) can also be used.
Blend Ratio
70/30 to 90/10 (CA/HPC) for taste masking.
85/15 to 97/3 for sustained release.
Coat Level
10-15% for taste masking.
16-28% for sustained release.
Form of Active--Rotogranulated APAP with smooth, approximately spherical shape. Size of 170-270 microns.
Otherwise same as above for I.
Form of Active--Rotogranulated with a carrier such as lactose which results in a smooth, approximately spherical shape. Binders such as povidone can be included in the Rotogranulated particles at levels of 1-10%. Same granular size as in I.
Coat Level 7-15% for taste masking.
Otherwise same as above for I.
Active-Dexibuprofen lysine (or other salts of ibuprofen such as Sodium Ibuprofen)
Form of Active--Rotogranulated particles can include a binder such as Povidone at levels of 1-10%. Granular size of 170-270 microns.
Coat Level: 10-18% for taste masking.
Active--Naproxen Sodium
Form of Active--Rotogranulated as in Example IV.
Otherwise same as above for IV.
______________________________________Total Coat 12% w/wCharge 4000 gms ibuprofenTotal Polymer 545.45 gmsPolymer 1 65% w/w CA 354.54 gmsPolymer 2 10% w/w CAB 54.55 gmsPolymer 3 25% w/w HPC 136.36 gmsPolymer Soln 10% w/w 5454.55 gmsSolvent 1 80% w/w acetone 3927.27 gmsSolvent 2 20% w/w methanol 981.82 gmsTotal Batch 4545.45 gms______________________________________
______________________________________Total Coat 12% w/wCharge 4000 gms ibuprofen 480 gms pseudoephedrineTotal Polymer 545.45 gmsPolymer 1 60% w/w CA 327.27 gmsPolymer 2 40% w/w HPC 218.18 gmsPolymer Soln 8% w/w 6818.18 gmsSolvent 1 80% w/w acetone 5018.18 gmsSolvent 2 20% w/w methanol 1254.55 gmsTotal Batch 5025.45 gms______________________________________
______________________________________Total Coat 12% w/wCharge 4000 gms APAP 480 gms pseudoephedrine 32 gms chlorpheniramine 240 gms dextromethorphanTotal Polymer 545.45 gmsPolymer 1 70% w/w CA 381.82 gmsPolymer 2 30% w/w HPC 163.63 gmsPolymer Soln 10% w/w 5454.55 gmsSolvent 1 80% w/w acetone 3927.27 gmsSolvent 2 20% w/w methanol 981.82 gmsTotal Batch 5297.45 gms______________________________________
______________________________________Total Coat 12% w/wCharge 4000 gms aspirinTotal Polymer 545.45 gmsPolymer 1 85% w/w CA 463.64 gmsPolymer 2 15% w/w HPC 81.82 gmsPolymer Soln 8% w/w 6818.18 gmsSolvent 1 90% w/w acetone 5645.45 gmsSolvent 2 10% w/w ethyl acetate 627.27 gmsTotal Batch 4545.45 gms______________________________________
______________________________________Total Coat 12% w/wCharge 4000 gms loperamide HClTotal Polymer 545.45 gmsPolymer 1 80% w/w CA 436.36 gmsPolymer 2 20% w/w HPC 109.09 gmsPolymer Soln 8% w/w 6818.18 gmsSolvent 1 80% w/w acetone 5018.18 gmsSolvent 2 20% w/w methanol 1254.55 gmsTotal Batch 4545.45 gms______________________________________
______________________________________Total Coat 12% w/wCharge 4000 gms APAPTotal Polymer 545.45 gmsPolymer 1 85% w/w CAB 463.64 gmsPolymer 2 15% w/w HPC 81.82 gmsPolymer Soln 8% w/w 6818.18 gmsSolvent 1 80% w/w CH2 Cl2 5018.18 gmsSolvent 2 20% w/w methanol 1254.55 gmsTotal Batch 4545.45 gms______________________________________
Various other medicament combinations are prepared by coating desirable dosage ranges of medicaments cimetidine, ranitidine and nizatidine and combinations of two or more of pseudeuphedrine HCl, chlorpheniramine maleate, dextromethorphan HBr, diphenhydramine HCl or citrate, acetaminophen, ibuprofen and naproxen in accordance with the procedure and coatings of any of Examples I-XI
While the use of fluidized bed coating has been described in some detail as one preferred method for making the coated granules that are utilized in the invention, other techniques for making the coated granules may be used. Such other techniques include various microencapsulation techniques such as coacervation and solvent evaporation.
The following examples XI-XIV describes preparation of chewable tablets.
The ingredients displayed below, are sieved, dry blended, and compressed by standard procedures into round (disc shaped) chewable tablets, each weighing 1100 milligrams. The tablets had diameters of 9/16 inch, thicknesses of 0.573 centimeter, and had volumes of 0.919 cubic centimeter. Each tablet contained 200 milligrams of active ibuprofen per tablet, from coated granules prepared in accordance with the procedure of Example 1 containing 15 weight percent coating in which the proportion of CA:HPC was 85:15% w/w. The table below displays the ingredients, mg/tablet, percent, and grams/batch sufficient to make 10,000 tablets.
______________________________________Component mg/Tablet Percent Gms/Batch______________________________________mannitol 611.79 64.75 6117.94AVICEL PH101 71.76 7.59 717.65aspartame 11.84 1.25 118.41citric acid (anhyd) 5.74 0.61 57.41flavor 4.31 0.46 43.06PROSWEET 2.87 0.30 28.71Mg stearate 9.33 0.98 93.29coated ibuprofen 227.27 24.05 2272.70______________________________________
The following table displays some typical proportion ranges for the ingredients that were used in Examples XIII:
TABLE______________________________________Component Range of Proportions, %______________________________________mannitol 30-70AVICEL PH101 5-12aspartame 0.5-3citric acid 0.1-2flavor 0.2-2PROSWEET 0.1-2mg stearate 0.4-2coated ibuprofen 10-50______________________________________
The functions of the several ingredients and some typical replacements for them are as follows:
Mannitol is a sweetener. It can be replaced by dextrose, fructose, sorbitol, compressible sugar, or lactose;
Avicel PH101 is microcrystalline cellulose. It is used as a tabletting aid, e.g. to impart hardness. It may be replaced with tricalcium phosphate;
Aspartame is an artificial sweetener. It can be replaced with others such as saccharin;
Citric acid is used as an acidifying agent to enhance the taste. It can be replaced by other acidifying agents such as malic acid;
The flavoring agent can be any flavoring agents such as vanilla, peppermint, orange, cherry, or spearmint;
Prosweet is another sweetener. It can be replaced with other materials such as saccharin, aspartame, natural sugars; and
Magnesium stearate is a lubricant (to lubricate the dye walls and punches used during the tablet compression procedure). It can be replaced by talc, stearic acid, calcium stearate, zinc stearate, or the like.
The scope of the present invention is not limited by the description, examples and suggested used herein and modifications can be made without departing from the spirit of the invention. For example, other components may be added to the tablets including additional actives, various flavorings, preservatives and other pharmaceutical excipients. The present invention may also be used to provide a sustained release and/or chewable form for vitamins, minerals or other nutrients.
Application of the compositions and processes of the present invention for medical and pharmaceutical uses can be accomplished by any clinical, medical and pharmaceutical methods and techniques as are presently and prospectively known to those skilled in the art. Thus it is intended that the present invention cover the modifications and variations of this invention provided that they come within the scope of the appended claims and their equivalents.
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Ken Florance, Director of Content Delivery for Netflix, posted this on Wednesday on Netflix's techie blog with, as promised, separate lines for AT&T and Verizon fiber-optic offerings from their DSL offerings. Florance writes, "The chart now gives a fairly complete look at performance on top networks, with additional insight into how different technologies (DSL, Cable, FTTx) impact potential throughput."
As expected, there's a significant separation between DSL and cable and cable and fiber to the home/curb, but wait…why is AT&T's fiber network performance mired among everyone else's cable network?
One explanation I got to a question at the Netflix tech blog is that AT&T's U-verse "fiber optic" offering is fiber only to "the node," or a box outside near people's homes, with DSL carrying the signal the rest of the way. So it shouldn't be compared to Verizon's FiOS, which is glass all the way to the home.
update: This graph has generated a ton of comments on Reddit, as apparently there are a ton of unhappy AT&T U-verse customers out there. U-verse is AT&T's fiber broadband offering. Its "elite package" at $74 a month gets you download speeds of up to 6 megabits per second. They quote you the high; normal mileage is almost always less, but the roughly 2.25 megabits per second that Netflix is showing is quite less.
jfasi on Reddit was happy to see this chart:
Netflix is doing something excellent here. They are using their rather unique position to keep tabs on ISP shenanigans. By making this data public, they are pressuring the ISPs both to remove any and all restrictions on their own service, as well as highlighting genuinely measured data about various providers.
This sort of negative publicity is exactly what is needed to highlight and combat net neutrality violations. Well done, Netflix.

subset: commoncrawl


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Sunday Link Love, Volume #131
Happy Sunday!
Hope you've been having a lovely weekend! We spent our Saturday with my husband's family to celebrate his mom's birthday. Mellan went on vacation to my parent's house, and we'll be picking him up after lunch. Whether or not he'll want to come home, well… To say he is spoiled by mom is an understatement!
- Muse looks at Maybelline's new Coral Burst Blush [Musings of a Muse]
- Sugar and Spice and Everything Nice with Jo Malone — or maybe not so nice [Kafkaesque]
- Estee Lauder's new cream eyeshadows are a pass [Dustin Hunter]
- Fashion Week hair that you can try now [Refinery29]
- One more reason to buy Guerlain's Coup de Foudre [Cafe Makeup]
- The nails at Gareth Pugh [The Cut]
- A new Bobbi Brown Shimmer Brick — Lilac Rose [The Beauty Look Book]
- How Charlotte gets her skin looking flawless [Lipglossiping]
Discussion and debate are highly encouraged, and we expect community members to participate respectfully. When asking a question, please check the FAQ section (above) for information about purchasing, price, dupes, and the like. If you have general feedback or need technical support, please contact us.
Comments that include advertisements, self-promotion, insults, etc. may be in violation of our comment policy and subject to deletion. Please see our comment policy for more information.


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Archive for "Pandora's Tower" Tag
Toru Haga – Developer of Pandora's Tower Talks About Some Wii U Ideas
Future Wii U title is now obviously a reality
Pandora's Tower confirmed for US release
Pandora's Tower Review
By Cameron Foster Set in the continent of Imperia, divided into 9 kingdoms, in the wastelands of Akanos. A ta... Read More
Pandora's Tower HD Video Walkthrough | Game Guide
Complete Pandora's Tower's single player campaign with the help of this video guide. ***Please note this wa... Read More
Pandora's Tower Launch Trailer Is Here
We have the launch trailer for Pandora's Tower. In Pandora's Tower you take on the role of Aeron, a soldi... Read More
Pandora's Tower Wallpapers in HD
Check out these Pandora's Tower wallpapers in HD. You can use these wallpapers for your PlayStation 3, iPad, ... Read More
Pandora's Tower releasing in Europe in April
Pandora's Tower, the third of the holy trinity of the Japanese RPGs whose releases everyone's been clamourin... Read More
Promote Xenoblade Chronicles And Win The Last Story And/Or Pandora's Tower
Do you love Xenoblade Chronicles and want to to sing it to the mountains? And would like a shot at winning t... Read More
The Last Story and Pandora's Tower releasing in Europe next year
Nintendo has announced in their updated release schedule for this year and some for next year, that The Last... Read More
Xenoblade, The Last Story and Pandora's Tower will see American releases 'if there are business opportunities'- Reggie Fils-Aime
Some time ago, Nintendo announced that they will not be releasing their three major upcoming games for the W... Read More
RUMOUR CONTROL: Nintendo Localizing Xenobloade, The Last Story and Pandora's Tower in North America
A few weeks ago, that the three new games they'd developed, Xenoblade, The Last Story and Pandora's Tower (w... Read More
Nintendo Unveil Action RPG 'Pandora's Tower' Trailer
[HTML1] In January, Nintendo teased us with a mysterious Wii game on their official website called 'Pandora... Read More


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The National Strategy for Biosurveillance (Strategy) calls for "a coordinated approach that brings together Federal, state, local, and tribal governments; the private sector; nongovernmental organizations; and international partners" to enhance existing biosurveillance capabilities and, where necessary, develop new ones that provide decision makers and responders with the essential information they need to mitigate impacts of threats to health and associated economic, societal, and political consequences. The Strategy recognizes that a well-integrated national biosurveillance enterprise can saves lives by providing essential information for better decision making at all levels. The National Biosurveillance (BSV) Science and Technology (S&T) Roadmap, published in June 2013, identifies and prioritizes the R&D efforts needed to provide decision makers at all levels with the accurate and timely information needed to develop effective responses to incidents that threaten health. The R&D objectives in this Roadmap are designed to facilitate the accomplishment of the core functions and actions identified in the Strategy and Implementation Plan, respectively. Consistent with the Strategy and Homeland Security Presidential Directive (HSPD)-21 entitled Public Health and Medical Preparedness, this Roadmap focuses on S&T for anticipating significant health incidents involving naturally occurring, accidental, or manmade threats; rapidly and accurately identifying and characterizing incidents that occur; and effectively integrating, sharing, and analyzing the information available at each stage. Achieving the S&T objectives in this Roadmap will permit better decision making during an incident, resulting in improved mitigation, response, and recovery that may ultimately save lives and improve health. This symposium will address The National Strategy for Biosurveillance identified core functions which include
Click for more information and to RSVP: http://www.knowledgefoundation.com/viewevents.php?event_id=318&act=evt
We're always happy to get feedback from our users. Please use the Comments form to send us your comments, questions, and observations.
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How Much Do the Real Housewives of New York City Make?
Wondering how much the stars of The Real Housewives of New York get paid? Former star Simon Van Kempen (aka fired Housewife Alex McCord's oddball husband) may have just let slip how much the Housewives are taking home.
Rob Shuter from The Huffington Post talked to Simon about the possibility of returning to RHONY after he and his wife had been dumped from the show. Simon wasn't too enthusiastic about returning, adding that the only thing he missed was "the $300,000 paycheck." Rob notes that this is only the reported paycheck, but if Simon is saying it we are inclined to believe that his wife was getting that sum. But then again, you never know with the McCord-Van Kempens.
There's no word on what the current slate of RHONY Housewives are getting, but reality show paycheck history suggests that the new cast members (Aviva Drescher, Carole Radziwill, and Heather Thomson) are probably not making as much as established cast members Countess LuAnn de Lesseps, Ramona Singer, and Sonja Morgan. The original three were probably getting paid as much as Simon says he and Alex were earning. However, after the premiere of what looks like an exciting, drama-filled season, the new Housewives might be eventually getting a paycheck boost.
Check out all of Wetpaint Entertainment's RHONY coverage.
The Real Housewives of New York Season 5 premieres on Monday, June 4 at 9 p.m. ET/PT on Bravo.
Source: HuffPo
Follow Maria Mercedes Lara on Twitter @maria_mercedes.
For the latest from Wetpaint Entertainment, Like us on our Facebook page at facebook.com/Wetpaint, or Follow us on Twitter at twitter.com/WetpaintTV.


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Unlimited water,Unlimited food
Load or reset the game, then execute the following BASIC commands before running or restarting the program.
Effect Password Unlimited food POKE 13401,165 Unlimited water POKE 13346,165
Contributed By: Dragon King 187.
Know Something We Don't?
You can submit new cheat codes for this game using our Cheat Submission Form.
Have We Been Fooled?
If you see a non-working or fake code in the list above, let us know by using our Problem Submission Form.


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Secondary Education - English
Students applying to the Secondary Education (English) program are accepted for admission in either the fall or the spring semester. Although there are no strict application deadlines, candidates will be best served if applications are received by December 1 for entrance in January and by March 1 for entrance in September.
In general, a candidate for admission to the University of Hartford:
For admission to programs in the Department of Education,16 units of secondary subjects are expected and should include the following as minimal:
English 4 units
Social Studies 2 units
One Language 2 units
Science 2 units
Mathematics 2 units (including 1 unit of algebra)
Other Academic Subjects 4 units
Office of Admissions and Financial Aid:
Students entering the professional phase of their secondary education programs meet faculty for lunch. more


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Pig 'finishing' facility approval
Posted: February 18, 2013|
PLANS to build a 'finishing' facility housing more than 1,000 pigs have been approved.
Mercer Farming, which currently operates from 19 farms in the local area providing Packington Pork for supermarkets, has been given the go ahead for two new pig houses, as part of its outdoor-rearing (freedom foods) operation.
Outdoor-reared pigs are both bred and live outside for the first 12 weeks of life, with the second half of their lives spent indoors on straw bedding.
The sheds which house the pigs for this time are often referred to as "finishing houses".
It is this facility which has been approved for Bonthorne Field, off Dogshead Lane, Barton-under-Needwood.
This will not be used as a slaughterhouse.


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Most recent posts
Teaching English Affectively An Interview with Juan Alberto Lopez Uribe
posted to Vicky Loras's Blog on Wed 25th Sep 13
Juan Alberto Lopez UribeThis new interview shows a lot of things to me and you will see them too: it is with Juan Alberto Lopez Uribe, with whom we have never met in person, but we have collaborated perfectly online! Juan created a video for our children at ...
With all her love for education and collaboration: Interview with Ika Chieka Wibowo
posted to Vicky Loras's Blog on Thu 22nd Aug 13
Ika WibowoI am delighted to present an educator from Indonesia in an interview she has given me: Ika Wibowo from Indonesia! I connected to Ika on Facebook from my first days there, about a year ago and I admire her for her passion to teach, connect and share! ...
Guest post by Dimitris Primalis (@dprimalis) Information gap tasks with the aid of technology
posted to Vicky Loras's Blog on Fri 16th Aug 13
Dimitris PrimalisIt is an honour to host once again on my blog, an educator I am very happy to know, to have worked with and call a friend: Dimitris Primalis. I admire him for his passion for teaching, his integrity, professionalism, support to other educators ...
Most popular posts
Blog Challenge Whats Your Story?
posted to Vicky Loras's Blog on Sun 9th Oct 11
My sister Gina and I, both educators, made a big change in our lives - What's Your Story?I am very happy to announce my first ever blog challenge called: What's Your Story?After writing on my blog about my experience on moving to Switzerland after ...
TESOL France 30th Colloquium Day Two (#TESOLFr)
posted to Vicky Loras's Blog on Fri 11th Nov 11
And after the excitement of Day One…Day Two came along for all of us to learn, connect and have fun!Mike HarrisonI started my day with Mike Harrison's super session Before Words: Ideas for Using Images and Sound in the Classroom. It was the first ...
TESOL France 30th Colloquium Day One (#TESOLFr)
posted to Vicky Loras's Blog on Wed 9th Nov 11
Last year was the first time I attended TESOL France – it was a huge success from many aspects. First of all, the plenaries, workshops and talks were all fantastic and I learned so much. I met a lot of people I had only been interacting with online on ...
Latest posts linking here
33rd ELT Blog Carnival, Using Songs and Music in Class
posted to A Journey in TEFL on Thu 1st Aug 13
Welcome to the 33rd ELT carnival. The theme isUsing Music and Songs in EFL Classes and today I'm happy to introduce a wonderful album to you. If you are ready grab a cup of coffee (hot or cold), put the record on and enjoy …Here we beginSIDE 1From ...
Weekly Round up in ELT 22/02/2013
posted to ELT SquaredELT Squared | Exponential Professional ELT teaching Growth on Fri 22nd Feb 13
Photo Credit: Ludgonious via Compfight ccHi everyone. This week sees the last Weekly roundup before I start my DELTA course [insert dramatic music] As such I have been a bit behind with my reading this week but I did have enough to make a round up of the week. ...
January 2013 in a nutshell or on a post
posted to Doing some thinking on Fri 1st Feb 13
Even though I've been travelling for more than a week now, I was able to have a look at a couple of interesting blog posts prior to getting to the US. As you most certainly know, there are lots of good texts out there. These are just a couple of posts ...


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We bring you the most revealing F30 3-series FEP (final evaluation phase) test car video yet — 2 minutes of spy footage. The video reveals the following things: Fixed piston calipers, Possible lightweight calipers being tested, LED turn signal indicators, Regular bulb brake lights, Appears to be undergoing sound check/testing. Enjoy the video inside.
We bring you the first photos of a red F30 3-series sedan spied, showing the best F30 interior photos yet. The interior photos are telling, revealing a semi-black panel display, lane change assistant, and auto-start stop technology.
See our analysis and photos inside.
Here are some new renders of the F30 3-series sedan, by German publication Auto Test. These are some of the more attractive renders we've seen and are clearly based off the F10 5-series, but with some attention to paid to previous F30 spy photos.
The rear 3/4 view is particular attractive. However, the renders are missing some new styling features revealed in the most recent F30 spy photos, such as the double character lines.
We continue bringing you what may appear to be live coverage of the various F30 3-series FEP test cars driving around the streets of Munich. This new set features in-action photos of a Carbon Black F30 and Alpine White F30. Enjoy the entire gallery inside, now 40+ photos.
We have added yet another set of BMW F30 3-series photos, with the best closeups available yet. This model is an Alpine White F30 325i/328i caught while parked, which provides us some great looks at certain camouflaged elements such as the headlights, grilles, front bumper, side view mirrors, and rear lights. Check out the new set of photos inside.
The F30 3-series FEP (final evaluation phase) stage sedans were out testing in force today! This is the third sighting we are bringing you photos from, and this time the F30 was spotted in Alpine White. Enjoy the photos!
Sometimes when it rains it pours. We bring you even more F30 spy photos today – this time of a black/dark blue F30 335i showing off F30′s double character lines, aggressive front end with squared off angel eyes and some new wheels. Check out the photos inside.
The 2012 F30 3-series sedan has finally dropped its heavy camouflage to reveal a handsome and evolutionary design from the current E90 3-series sedan!
As expected, the F30 3-series retains its sporty and squat design, with short overhangs and wheels pushed to the corners. However, the front end adopts BMWs current design language, with a sleeker sloping front fascia with widened kidney grilles. The rear lights remain classic L-shapes and the car retains the prominent character line throughout its doors.
The F30 3-series sedan is expected to be … CONTINUED
Here is an updated F30 3-series generation debut and sales timeline, as speculated by SCOTT26. The F30 3-series sedan will be announced in November of this year, coinciding with the Olympics. It will then make its public debut at the 2012 Geneva autoshow in March of 2012 and be on sale shortly thereafter.
Catch the rest of the timeline, including some insight into the 3-series Gran Turismo model inside…
The next generation F30 3-series is nearly upon us (we're expecting info on it later this year), so what is your improvements wishlist for the next 3 series? BMW does read the site and comments, so come share… you never know, your wish may be granted.
Here is a new rumor regarding the next generation F30/F32 M3′s powerplant – that a 3.3L V6 tri-turbo motor is a possibility! One turbo would power the motor generally, and the other two turbos would each be dedicated to 3-cylinders each.
Here are some of the clearest shots yet of the F34 3-series GT in testing, from some different perspectives than we've previously posted. We must say, the F34 GT looks much better in motion than at standstill.
Here are a couple new photos of the F34 3-series GT in testing runs on the streets. The 3-series GT will offer a simple hatch function rather than the twin trunk arrangement on the 5er GT. Spotted here is a 6 cylinder turbo version (335i or 335d).
We're excited to bring you the first spy photos of the 3-series Gran Turismo (GT) which will be released with the next generation of 3-series vehicles. With a sleek trunkline and frameless windows, the 3-series GT looks to be much lower and sleeker in shape than the 5-series GT and appears to be generally sportier in nature. The 3-series GT will offer a simple hatch function rather than the twin trunk arrangement on the 5er GT. Spotted here is a 6 cylinder turbo version (335i or … CONTINUED
While BMW continues development of the new F30 3-series set to debut in Spring 2012, German Auto Motor und Sport now reports about an interesting rumor: BMW is said to expand their lineup with a 4-door coupe based on the F30 platform. Internally called F36, BMW seems to consider 4-series for the name of this model. According to AMS, BMW is currently working on a first design model to showcase the car internally. Compared to the F30, the 4er is said to be 4cm or … CONTINUED
Car and Driver renders the F30 3-series sedan, one of the better ones that we have seen. We'll know soon enough as official F30 pics and details should be released by late this year, and its its world public debut just a few months later at the 2012 Geneva autoshow in March of 2012. The F32 coupe will be unveiled a year later in 2013.
Follow our complete F30/F32 coverage at: http://www.bimmerpost.com/3-series/f30/
These are the first pictures of a early hybrid prototype for the next generation 3 series from BMW, as indicated by the "Rescue" stickers on its doors (which has been present on past hybrid BMW test vehicles).
The F30 3-series will be the first 3-series hybrid from BMW and will adopt much of the technology from the upcoming hybrid F10 5-series. The F30 hybrid will be released some time after the diesel and petrol F30 versions are released next year.
Besides serving as proof of an upcoming F30 … CONTINUED
It appears that one of the BMW Vision Efficientdynamics car's more overt and distinguishing design features – the squared-off angel eye lights, will appear on the upcoming F30 3-series. This is the first we have seen this angel eyes design on a production BMW.
We first began seeing the squared-off angel eye lights on the VED concept car, a design concept which flowed down in less radical form to subsequent concept cars such as the Gran Coupe Concept and the 6-series Coupe Concept (all pictured below). … CONTINUED


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Cobalt blue dress? Neon booties? Oh, no she di'nt! Those day-glo disasters have us reaching for our sunglasses. Snooki, child, this is just wrong. The pint-size Jersey Shore guidette was at The Grove yesterday, filming an appearance for Extra, when she rocked up in this outfit. We feel like the lady who got photobombed in the picture on the left. It looks like she's staring at Snookums shoes and trying not to giggle. One thing we'll say, though, is that an outfit this mismatched takes commitment (and a genuine misinterpretation of fashion). And she does look like she's owning it.
WTF Fashion!
Scott Disick: Fashionable Or Foolish?
Oh, Scott Disick. You, who single handedly insure Brylcreem stays in business. You, of pointless fame. You, who thinks you're the biggest baller this side of the planet. This is Scott filming a segment of Kim And Kourtney Take New York. Behold his lavender jacket, his icy blue tie and the shoe minus the socks — because he's European like that. We're going to try and not influence your judgement on this outfit. Because we're giggling too hard! Let him have it, ladies and gents. By that we mean, please vote and tell us what you think, of course.
[Photo: Splash News Online]
What's Up With Geri Halliwell's Bridal Couture?
Geri Halliwell probably got the two things mixed up on her head. This was not her wedding, it was a party. And now she's the laughing stock of everyone who's looked at these photos. Geri turned up at the 6th Annual Raisa Gorbachev charity gala in London yesterday dressed like — this. Can we get a "Here Comes the Bride"?
Correct us if we're wrong, but does this not look like a wedding dress? It's a corseted, strapless, layered, tulle white gown. Do the math, Geri. And to add insult to injury, she looks orange. Big fan of the Spice Girls (yeah, so what), but this is something we just can't get on board with. And if this what she wears to a party, can you imagine what she's wear if she actually got married?
Battle Of The Wacky Fashion Week Outfits: Jessie J. Vs. Nicki Minaj
It looks like Jessie J is taking a page right out of Nicki Minaj's wild Harajuku Barbie notebook. Last week Nicki rocked a colorful and crazy ensemble to NY Fashion Week and earlier this week Jessie followed suit and hit London Fashion Week sporting an equally colorful and bizarre outfit. Do you think Jessie was inspired by Minaj's gumballs? Or was the Brit songstress challenging Nicki to a wild fashion duel? Check out our gallery of Jessie J below and tell us which pop diva rocked the crazier outfit to Fashion Week. [Photo: Getty Images]
Presented Without Commentary: Big Bird Gets A Dye Job
That's Richard Simmons heading for one of his workout classes in Beverly Hills. Yes, he is wearing pearls and an orange tutu with weird striped boxers peeking out. We have no other words except, "My EYES"!
The Olsen Twins Sell $35,000 Backpack For Fashion Label The Row
The Olsen twins have always been profoundly interested in fashion (though sometimes it is extremely hard to tell), so it only makes sense they would want the rest of us to be as deeply invested as well. So deeply invested, in fact, that we would consider taking a homeowner's loan to afford their new black leather croc backpack, available through their line The Row. How much does it cost to own such a life-changing bag? Somewhere between $35,000 and $39,000, depending on where it's for sale. Did we mention that it has a drawstring? Did we mention that it's ONE SINGLE BACKPACK?
New York's Barney's will be carrying the bags, and as their fashion director Amanda Brooks told Fashionista.com about the Olsens' backpack, 'I think if you were every going to spend $39,000 on a bag, that's the bag you should buy because I think you'd wear it for a really long time. There's enough design to make it interesting and beautiful but they truly are classic bags–and I think you also might be the only one who has it." Apparently two of the bags have been pre-ordered, which means they won't even be unique, you crazy rich socialites! If the Olsens made these bags as a hilarious prank, then bravo. If not…then these two are certifiable marketing geniuses.
[Photo: Getty Images]
Kourtney Kardashian: Put Away the Jumpsuit
There are so many things wrong with this picture, it's blowing our minds. Kourtney Kardashian is in flats! Which means pigs have officially grown wings. But that's not the real problem here. The problem is the flats with that jumpusit. With all her kurves, Kourtney is rather vertically challenged so a jumpsuit is never a good idea anyway, because it makes the body look squat. That's like Style 101, right there. But the fact that she made it worse by wearing a yellow, floral print is just beyond. And the piece de resistance? The visible black bra at the back. Can we also point out that is an extremely ill-placed belt as well?I It's giving her a very pronounced stomach, hips and a cleavage which we're normally good with, but in this picture, they're all so wrong. Whutup, Kourtney?
[Photo: Splash News Online]
Kellan Lutz Or Cap'n Carrot Top? We'll Let You Decide
We can all agree that Kellan Lutz typically looks pretty fine, particularly in the chest-ular region. However, while visitng the Ciroc Cabana Club in the Hamptons earlier this week, the Twilight star was fighting the hot harder than he fought to get that sailor shirt on over his huge shoulders.
We don't know what's worse…okay, yes we do, it's the bleached perm. Putting the locks aside for a moment, there's also Kellan's orange tan, nautical ensemble and rope belt to be taken into consideration. If you're stranded on a ship at sea and your belt breaks, sure, go crazy. You can use an electrical cord if you want, but on dry land? What do you think? Do you see only Kellan's hotness shining through his questionable clothing choices, or does he in fact look like Carrot Top, if Carrot Top's mom sewed him an outfit out of an old American flag?
[Photo: Splash News Online]
When Lady Gaga Met The Children
Lady Gaga, swathed in a red maxi dress, blue hair and a blazer, swept through Toronto airport yesterday. The blue hair had also made a rather raunchy appearance on Gaga's nether regions the night before at the 2011 MuchMusic Video Awards. The singer's progress towards her space ship was only halted by this little tyke here. We're fans of this girl who looked rather terrified during her encounter with Gaga. This is how we imagine the conversation went.
Lady Gaga: LITTLE MONSTER!
Little Girl: *If I don't look at her directly, maybe she'll disappear*
Lady Gaga: Little monster, It's me, Mamma Monster! Let me cocoon you with the surreal blanket of my love!
Little Girl: *Maybe I'll start backing away slowly*
Lady Gaga: …. We'll change the world one sequin at a time!
Little Girl: *Someone help me*
Lady Gaga: …Don't be a drag, just be a Queen. Like me! To the spaceship!
Little Girl: MOMMY!
[Photo: Splash News Online]
Matthew McConaughey Turns Marlboro Man: Love It Or Hate It?
Howdy, partner! While last night's Bernie premiere wasn't the first time Matthew McConaughey has shown off his new 'stache, his decision to top off his ensemble with a cowboy hat certainly brings out the Marlboro Man vibe—or the John Holmes vibe depending on your cultural reference point. Do you dig the look, or would you rather he bring back the smooth-faced Surfer, Dude aesthetic we've seen for years? Check out the gallery below for shots of mustachioed Mateo with wife Camila Alves and co-stars Jack Black and Shirley MacLaine. You have to assume movie is relatively serious if Jack isn't pulling his Kung Fu Panda craziness on the carpet.
[Photos: Getty Images]


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Tuesday, April 3, 2012
I really was there
The lovely ladies at the OCADU Student Gallery got a pick of me with my work (I wish I could say they were all mine, but no, just the rainbow dream) at the Neon show.
You can check out the rest of the pics from the show on their tumblr.
So much good stuff.
Posted by Brianna Lowe at 4/03/2012 No comments:
Labels: gallery shows, Press
Monday, April 2, 2012
beat it red
Labels: video
the edge of the earth
Labels: video
Subscribe to: Posts (Atom)


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The CI 13 release contains a new Minimap productivity tool and several improvements to servers and deployment.
Included in this release:
- Minimap Provides Source File Overview
- Tomcat Server Connector Fixes
- Additional Connection Protocol for WebSphere
- Context Root Added to Deployment Assembly Properties
- Improved Performance of the PhoneGap Plugin Wizard
- Miscellaneous Key Fixes
Minimap Provides Source File Overview
When you're working with a large amount of code, the Minimap makes it easy to navigate through your source. Most developers have a "mental map" of how their code is formatted. This new view shows you the bigger picture at a glance and allows a quick jump to the section you need. The Minimap works for all source editors including Java, JavaScript, HTML, etc.
Tomcat Server Connector Fixes
A number of fixes were made to the Tomcat server connector to make both auto-deployment and context deployment robust and more intuitive. Several issues around the storage of configuration files in the workspace and changes to the server working directory were fixed.
Additional Connection Protocol for WebSphere
In addition to IPC, SOAP is now available as a connection protocol for all WAS servers.
Several issues have been fixed with the in-workspace deployment mode.
Context Root Added to Deployment Assembly Properties
The deployment page has been reworked for Web projects to handle the context root setting. This puts all Web project related settings like the WebRoot folder, context root and the archive name on a single Properties page.
Improved Performance of the PhoneGap Plugin Wizard
The PhoneGap plugin wizard has been reworked so that it is immediately usable on invocation (prior to this fix, the wizard could take a few minutes to be usable). The list now shows a fixed number of plugins based on your filtering criteria.


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Legendary senior writer, Packers lead blogger & NFC North columnist jclombardi presents Packers headlines.
Packers wouldn't top Bucs' modest offer to Crabtree: Packers tight end Tom Crabtree accepted a two-year, $1.6 million contract with the Tampa Bay Buccaneers, after the Packers would not go higher than their one-year offer. Transition tight ends are common place in the NFL. Also, TE Williams and TE Quarless will do better than the gone cheesedungTV favorite. That's a shame!
With Jennings, Crabtree gone, Finley's future should be in Green Bay: With the loss of Greg Jennings and Tom Crabtree, the Packers will probably keep TE Finley.
Hawk takes pay cut to stay; Francois gets 1-year deal: The Packers see LB A.J. Hawk as a durable reliable player (just a guy too) in their middle defense. In 2013, they were unwilling to pay him $5.45 million in salary and bonuses, so Hawk accepted a pay cut. Shocking!
Jennings signs with Vikings: "It's A Business.": Last season, the Packers offered a contract extension worth about $10 million per year to WR Jennings. He declined it. In 2013, the Packers were not willing to do better, so the writing was on the wall. Jennings knew it pulling a Favre going to the the Vikings. No surprise.
Greg Jennings joins the Vikings: For Greg Jennings, the decision came down to Green Bay Packers and the Minnesota Vikings. The Vikings stepped up to the plate." True!
Jennings picks Minnesota, agrees to five-year deal: Greg Jennings' time with the Packers was over when the put his place up for sale. With the five-year deal with the Minnesota Vikings, his former team can look forward to seeing him twice a year within the NFC North.
Hawk accepts pay cut to return: Inside linebacker A.J. Hawk agreed to a pay cut. USA Today's Mike Garafolo reported Hawk's pay cut countering the planning $7.03 million against the Packers' 2013 salary cap. "Just a guy" stays with the Packers.
LB Brad Jones visits Titans: Free-agent linebacker Brad Jones is visiting the Tennessee Titans.. If he is smart, he will be gone too.
Zombo may not be in Packers' plans: The Packers do not show interest in bringing back restricted free agent outside linebacker Frank Zombo. Shocker! Really?
COMMENTARY: Fans, we do not know what to say, although all the Packers moves are good ones for their free agents. This is all predictable. Marginal backups are resigned and quality talent leave the Packers. Old story. The problem is the competition is catching up and the Packers have not made the moves to address their weaknesses, especially on defense.


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Status: Active
ISBN: 1-56905-231-x
weight: 3.7 lbs
in inches: 11.625 x 11.625 x 2.625
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Product Info
- Ages: 12+
- Players: 2-4
- Playing Time: 90-120 minutes
- Designers: Michael Rieneck, Stefan Stadler
- Art: Michael Menzel
World without End™
England in the early and middle 14th Century!
Journey to Kingsbridge, England, where 200 years ago Prior Phillip oversaw the building of the cathedral renowned as "The Pillars of the Earth." Now farmers, wool dealers, and builders seek wealth and prestige amidst a rivalry between the priory and merchants. As the plague reaches town, nothing remains as it once was.
World Without End is based on Ken Follett's best-selling novel. Strive to navigate turbulent events, ensuring and balancing your food supply, income, and prestige. Piety and loyalty remain vital, for you must cater to the upper classes. And precious medical knowledge is your greatest weapon against the Black Death. So, gather your power and spirit and rise above your rivals into legend!
- 1 game board
- 30 gold markers
- 100 cards (4 summary, 4 event, 48 action, 4 chapter)
- 57 markers (20 med, 11 plague, 12 piety, 14 loyalty, 1 favor)
- 10 die-cut tiles (7 building project, 3 covering)
- 41 wooden resource cubes (25 wood, 15 stone, 1 metal)
- 37 wooden commodity pieces (10 grain, 15 wool, 12 cloth)
- 16 wooden house pieces
- 1 wooden start player piece
- 4 wooden scoring tokens
- 4 player screens
- 1 tax die
- 1 bag
- 1 rulebook
Look for other games in these categories:
Series: Ken Follet


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Needs Based Digital Marketing
When you boil it down to its essence, consumer behavior is dictated by needs and wants. Consumers very rarely buy something solely because of their demographics.
In other words, demographics help us form a picture of who a consumer is who buys a product, but almost never do they tell us why.
This post by Jolina at the Online Marketing Blog talks about moving from targeting Demographics to something called "Momentgraphics" in digital marketing. She also provides a good example of what this means:
"Momentgraphics focuses on the periods of time in which we need to target prospects. For example, someone searching for the phrase 'cold medicine that works in less time' is the prime target for a company producing cold medicine. The demographics of that person are irrelevant because we know they are in a 'target moment' making them the target market. "
While I think "momentgraphics" seems kind of kludgy as a term, the idea behind it is sound, since it brings traditional needs based consumer insights to the digital immediacy of search engine marketing.
2 comments
- 1 Robin { 02.07.08 at 8:31 am }
I agree that focusing on time is important. Looking at this from a slightly different angle, a recent AdAge article talks about the need to look at interplay of consumer's time and risk in marketing:
While I agree that we don't by things only because of our demographics, characteristics like gender, age, geography still dictate many of our needs. (If I live in Alaska, I'm probably going to buy a warm winter coat).
Leave a Comment


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Hold down Control (PC) or Command (Mac) key + mouseclick to select more than one option
|Avg. Dinner Entrée
|Greater than $25
|$18.01 - $25
|$12.01 - $18
|$7.01 - $12
|Less than $7
Posted by Poppi S. on 01/25/2012
Pretty much obsessed with the white sauce and pita... and the buffalo wings! the owner and his daughter were at the registers taking orders. nice family feeling. seating left something to be desired but it's fast food not fine dining, right? so be it.
Posted by Honee1998 on 02/07/2011
Everytime i go back to NY to visit this is a must stop for me. Love the Chicken and regular gyro awesome awesome...going bk next week cant wait my mouth is watering already
Posted by Matt on 09/05/2010
It's like going back in time. My first trip was in 1974 to see the circus at MSG, then I told my friends about it and became required dining before and after concerts at MSG from high school and beyond. I still stop in for a quick lunch once in a while and the taste and preparation are exactly the same as they were 36 years ago and that's good! There is usually enough seating upstairs for the overflow and don't be afraid to share a table with other diners. Costs are very reasonable. I do remember paying around $2.50 for a gyro, but that was a long time ago. Try the Greek fries, they haven't changed either. With the pizza/salad concession opposite the Greek side, there is something for everyone. Enjoy!
Posted by Naomi on 08/02/2010
Been a customer here for over 30 yrs. No question...Gyro II is one of the best places in NYC for satisfying, quality sandwiches/food -worth every dime of their cost! Often crowded, the service is remarkably quick. My biggest challenge (at times) is locating a table/spot to enjoy my purchase!
Posted by Mr. Ty on 06/28/2010
Watery sauce (& too sweet) and the meat tastes wierd.
Posted by TST on 12/17/2009
I read the reviews and was so excited to try this place. I'm guessing the rave reviews are from people who rave about the food at a street fair or shopping mall. This was the most unauthentic gyro I've ever had. First of all, the meat was not even on the rotisserie but rather in an oven. It was orange colored and dry looking. The lettuce was brown. Tomatoes were mushy. Sauce - well you can read the other comments - it tasted like miracle whip to me. Who wants something sugary sweet on a gyro? Where is that tangy, onion-y, garlic-y, cucumber-y tzatziki? It's not even an option? Feta was low-quality. Left me craving a real authentic greek gyro. Astoria, I will never be unfaithful again.
Posted by ERSNY2LA on 11/27/2009
I am in NY visiting, having left 32 years ago for LA. I am looking forward to one of my must-stops when I come east -- a visit to Gyro II for 1 or 2 gyros! It used to be a must-stop en route to Knick games years ago, and I can't find a better gyro in CA. While the sauce may not be as authentic as tzatziki, I grew up on this sauce and make my own whenever I get a gyro at a Greek festival in LA. The person above who approximated the sauce is quite correct: mayo, thinned out with a little vinegar, a pinch of sugar, with some dill and paprika added. Yum! It's all what you are used to: this is part of NY comfort food to me. But I once tried to ask for a "yeero" pronounced the correct way, and I gave up after about 4 tries and said "Jiro". LOL.


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The Lumineers had us at first "Ho Hey," but their visit to VH1 headquarters a few weeks back really got our hearts and feet thumping. Looking the part in soft chambray shirts and suspenders, and with big smiles on their faces, they played a few songs before sitting down to talk about their move west from Brooklyn to Colorado and about hearing their music on television for the first time. All the while our photographer, Lauren Weissler, was tagging along to catch them setting up, hanging out, plugging in, and playing. We've named The Lumineers our You Oughta Know artists for July and August because we just can't get enough of their warm, roots-revival rock; the rest of you, though, who have helped to propel their album to the #3 spot on Billboard's Folk chart and #4 on the Indie chart, might have your own reasons for loving them. But check out the photos below and tell us: aren't you so charmed, too?
But wait, we have a surprise for you! We have a special, free MP3 download of "Big Parade" by The Lumineers here for you!
DOWNLOAD "BIG PARADE" by THE LUMINEERS (right-click, save-as)
[Photo Credit: Lauren Weissler/VH1]


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This edgy green has an interesting background.
One of style editor Michael Penney's favourite paint shades is Farrow & Ball's Arsenic. "The name comes from the toxic chemical originally used to produce this historic colour," he says. "It's a great accent colour, and I just used it to paint out a old console table in a fresh white hallway. It's so fun, but still grounded in history."
See more H&H paint picks in our Editors' Favourite Paint Colours gallery.
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Duke Energy warms customers about bill payment scam
CHARLOTTE– Duke Energy urges its customers in North Carolina and South Carolina to be alert for a new bill payment scam.
Since mid-November, more than 35 Duke Energy small-business and residential customers in the Carolinas have reported that they've been victims of this latest scam.
Some have lost as much as $900.
Under the scam, a customer receives an unsolicited phone call from a fraudulent individual who falsely claims to be a Duke Energy representative.
The fraudulent individual falsely warns that Duke Energy will disconnect the customer's electric service if the customer fails to make an immediate payment – usually within one hour.
The fraudulent individual instructs the customer to purchase a prepaid debit card – widely available at retail stores – then call the fraudulent individual back to supposedly make a payment to Duke Energy.
The fraudulent individual asks the customer for the prepaid debit card's receipt number and PIN number, giving the fraudulent individual instant access to the card's funds and the ability to immediately drain its balance.
In reality, Duke Energy never asks or requires customers who have delinquent accounts to purchase a prepaid debit card to avoid electric service disconnection.
Customers can make payments online, by phone, by automatic bank draft, by mail or in person.
Duke Energy customers who have delinquent accounts receive multiple notifications from the company over the course of several weeks prior to electric service disconnection – never just a single notification one hour before disconnection.
The company urges customers who suspect or experience fraud to hang up and call local police, then call Duke Energy or Progress Energy at the numbers below: Duke Energy customers – 800-777-9898; Progress Energy customers – 800-452-2777.


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Questions & Answers
Do you have questions about this product?
Get answers from real customers and in-house experts with AnswerBox.
Q:Is it safe to use as a moisturizer for your hairAsked on 7/25/2015 by R from Tampa, Florida
2 answers
A:I have never heard of it being used for that purpose before, however R&B hair moisturizer is a great alternative if you want something made specifically for that purpose, best of luck!Answered on 7/28/2015 by Rachel from Midwest
A:The avocado oil might be a bit tricky to remove from your hair, but I don't see why not! This might be a better treatment that you wash out of your hair with shampoo, then condition as normal.Answered on 7/26/2015 by Alexander from Lush Direct
Q:Is this good for people (especially young children) with eczema?Asked on 6/26/2015 by checkered
3 answers
A:Hi, well I absolutely LOVE King of Skin Body Butter for my super dry skin!
However, I do not have eczema and can not answer your question. Sorry and
I hope you find your answer.Answered on 6/30/2015 by Anonymous
A:It wouldn't be the best for it, I recommend something like Self Preserving Dream Cream for dry, sensitive skin!Answered on 6/30/2015 by Pauline
A:Fresh avocado is going to moisturize and soften and real cocoa butter is going to perfectly hydrate the skin in the gentlest way! There are no preservatives in this formula which can usually be irritating to sensitive skins.Answered on 6/30/2015 by Alexander from Lush Direct
Q:With using this product about every day about how long will it last for??Asked on 12/21/2014 by NRr
2 answers
A:I agree with the answer below, it really depends on how you use it though! If you use it after a shower on wet/damp skin, I would say it would last at least 3-4 weeks.Answered on 12/30/2014 by Elizabeth from LUSH Direct
A:If you use it in the shower with the water running over it, maybe a month of daily use. You will get more out of it if you turn off the water when done, apply it and just simply towel dry. I want to say maybe a month and a half. My massage bar that I keep away from the shower last longer. This one is just so moisturizing that I find myself wanting to buy it again.Answered on 12/27/2014 by mke lushie from Bedminster, NJ
Q:Do I need to use lotion after using this, or does this act like Ro's Argan and I don't need to moisturize after showering? Thank you!Asked on 11/22/2014 by Rachel from Minneapolis
3 answers
A:The king of skin is amazing. No lotion needed. I have never used anything like it. It makes your skin feel, look, and smell amazing.
Sent from my iPhoneAnswered on 11/25/2014 by Anonymous
A:You don't need to use a lotion after using King of Skin. It's very moisturizing!Answered on 11/25/2014 by Serena from LUSH Direct
A:No, you don't need to use any lotion after using this. Use it in the
shower, then pat yourself dry. It's all you need.Answered on 11/22/2014 by Anonymous
Q:What is the shelf life for KOS once it has been purchased?Asked on 8/20/2014 by Cturlo
1 answer
A:The shelf life for King of Skin is 14 months!Answered on 9/25/2014 by Kayla from LUSH DIRECT
Q:Most products have a "use by" date. How long can KOS be stored before use?Asked on 8/17/2014 by Cturlo from Huntington Beach, CA
1 answer
A:King of Skin has a shelf life of 14 months!Answered on 9/25/2014 by Kayla from LUSH DIRECT
Q:Do any other products smell like this?Asked on 6/28/2014 by Curious
2 answers
A:If your looking for that vanilla smell, I'd suggest Butterball Bathbomb, Vanilla Puff Powder, or Vanilla Dee-lite.Answered on 7/28/2015 by Rachel from Midwest
A:Scent-wise, Sympathy for the Skin is probably the closest to King of Skin, although they are not exactly the same.Answered on 9/25/2014 by Melissa S from LUSH Direct
Q:Are you supposed to rinse this off?Asked on 8/25/2013 by Tessica Jazzy
2 answers
A:Right after I turn my shower off and my skin is still wet, I glide this over and then pat dry with a towel. This works really well if your in search of some extra hydration, hope this helps!Answered on 7/28/2015 by Rachel from Midwest
A:King of Skin is best used in the shower or bath. Once you have massaged the oil into your wet skin, lightly rinse off, but ideally most of the oil will remain on your skin and absorb once you are out of the shower or bath. Pat dry gently so the oil stays on your skin and not on your towel! You can either apply the bar directly to your skin, or rub the bar between your hands and then apply the oil to your body.Answered on 9/25/2013 by Anonymous
Q:My Dad has vascular disease and needs to put lotion on his skin every day. His skin is so dry that its scaly. Would king of skin body butter work? Also, what soap would help him?Asked on 7/2/2013 by Kristal
1 answer
A:King of Skin is a great option to use in the shower or bath! You could try Honey I Washed the Kids or Sultana of Soap, which are both really gentle and moisturizing options. Taking a look at one of our shower smoothies, like Dream Wash could also be really helpful!Answered on 8/21/2013 by Anonymous
Q:Can you refrigerate this? I have no air conditioning and I am saving this as a gift for Mother's Day. It seems oily and I keep thinking that it's meltingAsked on 5/6/2013 by Heather from Portland, OR
2 answers
A:The body butters are made up of a combination of cocoa and shea butters, along with essential oils, so it does tend to melt down in warmer temperatures. You can absolutely store it in the fridge if you like, as it will not change the make up of the product at all.Answered on 9/20/2013 by Melissa S from LUSH Direct
A:Yes, I would! It takes a bit longer to melt on your skin but better that than a melted mess!Answered on 6/11/2013 by Dengail from Michigan
Q:Can this product be used on the face?Asked on 2/23/2013 by megan
1 answer
A:We do not suggest using King of Skin on the face, as it is formulated for use on the body. The skin on the face and body are very different, and therefore have different needs. For the face, we recommend sticking with the facial moisturizers and/or facial serum.Answered on 8/16/2013 by Melissa S from LUSH Direct
Q:How do I fit it in my body butter tin?Asked on 1/9/2013 by Anonymous
1 answer
A:Unfortunately, because of its shape, King of Skin does not fit in the body butter tin until you have used it and melted it down a couple of times. In the meantime, just make sure that you are storing it in a cool, dry place to ensure that it doesn't melt.Answered on 3/5/2013 by Melissa S from LUSH Direct
Q:How do I keep my hair from getting greasy? Since I have this on my back and hands, when I tried to dry my hair it was greasy and wet from this product.Asked on 2/25/2012 by Anonymous
4 answers
A:I'd recommend washing your hands with your favourite LUSH Soap after using the King of Skin and prior to touching the hair. If you are using it in the shower and finding your hair becomes greasy, I'd recommend applying the King of Skin on your body, first, and then shampooing and conditioning your hair. Be careful to avoid using the King of Skin bar on the neck, shoulders, or upper back where the hair may sit.Answered on 2/27/2012 by Megan from LUSH
A:try and wash your hands before you dry your hair! or try to pat some grease off with a spare towel after a few minutes of letting the oils soak into your skin!Answered on 4/3/2012 by clarrz from Illinois
A:I use body butter last in the shower, rinse off, wrap my hair in a towel, and use a 2nd towel to dry off. hope this helps!Answered on 5/4/2012 by Reannon from Bucks County, Pa
A:I had the same problem at first! I always put on King of Skin after I get out of the shower. First I put my hair up in a towel. Then, I lather on the KOS and put on my pjs (covering my back and shoulders). Then I wash my hands before I take down my hair and dry it. Grease problem solved! Hope this helps! :)Answered on 2/20/2013 by Danielle from San Diego, CA


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The Hendor Group's name has become synonymous with dedication, commitment and service excellence. Since its inception in 2000, Hendor has built up and enviable reputation within the transport industry. Driven By the vision to offer its clients the full spectrum of services, the company has over the years expanded its operations to include:
Under the careful leadership of a highly experienced and dedicated management team, the Hendor Group has significantly expanded its assets and customer base. Through the expertise, the group has experienced phenomenal growth and expansion and has evolved into a company which is capable of handling multi-million rand contracts with the same dedication , care and flawless capabilities as the smallest contract.
What separates Hendor from its competitors is its ability to partner with its clients in the true sense of the word, often becoming an extension of its clients business. Over the years Hendor has established phenomenal client relationships with all of its clients, big and small.
Over the past few years Hendor Transport has cemented its reputation as a reliable innovative and proactive transport solution company.
Since our inception in 2000, HENDOR has significantly expanded our asset and customer base and has accumulated vast experience and expertise in all facets of the transport industry.
View our Company Services
• Break Bulk: Clients are provided with a full logistics transport solution which operates nationwide and cross-border with the ability to transport any load from 1 ton to 34 tons.
• Cross-Border: These include a number of African countries such as Botswana, Lesotho, Swaziland, Mozambique, Angola, Maintain, Zambia, Zimbabwe and the Democratic Republic of Congo.
• Specialised Transport: The specialised transport services include the delivery of abnormal loads which are intended to use by the construction and mining industry. This includes the utilisation of specialised vehicles such as Trucks, Abnormal and Low Bed Vehicles, Containerised Cargo as well as Hazchem certified vehicles for the chemical industry.
• Port-to-Port: Need Transport offers a range of sea cargo services and has established strong relationships with the world's major shipping lines. Services include port-to-port delivery as well as transshipment for time-sensitive orders.
Reliability , efficiency and service excellence form the cornerstone of the Hendor Transport business and through the dedicated application of these principles, Hendor Transport is able to guarantee business success though on-time and accurate delivery schedules.
• Bulk blasting
• Drilling
• Quarry Blasting
• Trenching
• Pre-Split Blasting
• Sensitive Blasting
• Open Casting
Certified and Qualified to utilise NoneXTM, breaking rock and concrete in confined and sensitive areas is carried out effortlessly and with utmost care. Unwavering determination; the commitment to meeting client requirements and the ability to take on contacts both large and small with the same dedication and enthusiasm - has made Hendor Drilling and blasting the contractor of choice for some of the most intricate projects in South Africa. We have successfully completed many projects in the Civil and Road Construction industry. Hendor is a certified and qualified service provider in the civil construction industry. Our team of blasters are qualified to perform highly skilled drilling and blasting. We use high quality blasting products and accessories from reputable manufacturing companies in South Africa. We believe this contributes to the success of each project.
Hendor Drilling and Blasting is a level 4 BBBEE Company. We offer a dedicated and specialised drilling and blasting service to local - governmental and non-governmental, as well as international clients, involved in the civil construction and engineering industries.
Backed by vast years of collective experience, Hendor Drilling and blasting's management team provides a comprehensive support system to assist clients with contracts and deadlines.
With an impressive fleet of plant and equipment, the company offers a complete solution for each and every drilling and blasting requirement.
To supplement the Hendor Group's phenomenal and comprehensive service offering, the group established a new entity in March 2011, Known as the Hendor Corrosion Protection. the Piping, Painting and Lining division was added to compliment the turnkey solutions offered by Corrosion Protection division. Under the superb leadership of Janet Williamson, one of the first woman to head up a company in this specialised industry. The company pride itself in maintaining a professional, yet personal relationship with its clients. the ability to assist clients at short notice and ensure the timely delivery of high quality projects, regardless the project's size, has fostered unparalleled trust and loyalty from clients.
Hendor Corrosion Protection began with just a small group of experienced staff but has flourished and already experienced phenomenal growth in an exceptionally short period of time and currently employs 65 people.
View our Photo Gallery
Projects that have been completed in engineering, mining, governmental and non -governmental industries include work on structural steel, plate work and piping projects, locally as well as in Botswana, Namibia and Mozambique.Hendor Corrosion Protection adheres to high quality standards in the preparation of , as well as, the corrosion protection process. Its abrasive sandblasting and specialised coating is ideal for the petro-chemical, protective corrosive and mining industries. Hendor Corrosion Protection offers transport from the fabrication plant to its corrosion protection facility as well as any site locally, cross-border or abroad through its own in-house transport division. a team of qualified blasters are capable of blasting a SA2.5 or SA3, dependant of the clients specification. The blast room is equipped with nine 200 litre blast pots and a comprehensive safety system has been introduced to ensure the safety of all blasters.
For specialised coating Hendor corrosion Protection has eleven spray painters, each with their own assistant to ensure that the sanding and stripe coating is done prior to the paint being applied. All spray painters are trained and certified to Stoncor Africa (Pty) Ltd. Through this Hendor Corrosion ensures that client specifications are strictly adhered to. Furthermore weekly inspections are carried out by Stoncore and Sigma coatings. Hendor Corrosion Protection also provides rubber lining, ceramic lining and flow line services through specialise sub-contractors. All end products are of the highest quality and clients can feel complete peace of mind in the knowledge that a highly qualified team conducts all the humidity, dust and debris , blast profile readings and DFT readings between coasts. all of the aforementioned is followed as prescribed by Blastrite and Stoncore product data sheets. Hendor Corrosion and Protection is proud to be an approved supplier to major mining houses and subsequent fabricators.
Plot 230, 5th Road
Witpoort Estate, Brakpan, Minnebron
Tel: 011 743 2974 Fax: 011 743 2677