text:
Đăng ký
Tìm việc
- Buồng/ Kho vải/ Giặt là/ VSCC/ Làm vườn
Sơ lược về công ty
MGM Grand Ho Tram
Sơ lược về công ty :
The hotels and casinos of MGM Resorts International are among the most famous and spectacular destinations in the world. The key to the success of MGM Resort's renowned brands is the exceptional guest experience we deliver. And that demands passionate, energetic people in such areas as Food & Beverage, Hotel Operations and Gaming Operations. MGM Grand Ho Tram is the first of five resorts being developed by Asian Coast Development (Canada) Limited on the Ho Tram Strip in Vietnam, and will be ...
Quy mô công ty :
5 sao
Chi tiết công việc
Chức danh :
Assistant Housekeeping Manager
Nội dung tuyển dụng :
This position provides the day to day operation in areas relating to the Housekeeping Department and to administer the supervision of all housekeeping staff in conjunction with the Manager of Housekeeping; assists in general inventories by taking inventories for cleaning and guest supplies, recording all stock, and maintaining control of all issuing and to ensure that the Housekeeping Department operates according to the policies and procedures set forth by MMH. All responsibilities are to be performed in accordance with departmental and company policies, practices and procedures, as well as within the framework and intent of the Vision of the MGM property.
- Open the Housekeeping Department in the morning. Check night report and prepare Room Attendants' daily assignments. Take appropriate action in cases of under or over staffing.
- Check in Room Attendants and issue work assignments.
- Check in Floor Supervisors and issue work and key assignments
- Prepare daily rooms report before 10 A.M. submitting same to Front Desk noting any discrepancies and file copy.
- Supervise directly the cleaning and cleanliness of the Food and Beverage outlets.
- Establish cleaning programs to maintain cleanliness in these areas.
- Check public and staff washrooms to see that they are in good order and that all supplies are kept replenished.
- Check daily for maintenance conditions, make work orders for repairs in triplicate form (urgent reports made at once) and submit two to Engineering and retain one for file and follow-up.
- Check guest floors daily; check suites occupied and vacant; spot check occupied and check-out rooms daily; check all VIP and Special Attention rooms. Inform Floor Supervisors of missing items or work not properly performed. Inspect all back of house areas as well.
- Know all duties set out in all housekeeping job descriptions and ensure that systems are being followed. Check that Housemen and Cleaners vacuum all corridors, and maintain cleanliness in assigned areas. Inform Carpet Cleaner of rooms to be done and keep a record of them.
- Know room setups, color schemes, linens and inventories. No furniture to be removed from rooms unless instructed by the Director of Rooms or Director of Housekeeping.
- Keep open communication with Director of Housekeeping and have regular meetings.
- Be familiar with all operating equipment so as to instruct staff as to its proper usage.
- Responsible for implementing "ongoing" training programs, and projects as assigned.
- Monitor training of new employees.
- To recommend changes in the operating philosophy of the Housekeeping Department.
- To recommend changes in procedures for other departments.
- To oversee the cleanliness and maintenance of guest rooms, public and back of house areas, in accordance with procedures set forth by MMH.
- In the absence of the Executive and Assistant Director of Housekeeping, to be responsible for the smooth running and operation of the Housekeeping Department and all related areas.
- To deal efficiently with all housekeeping personnel.
- To assist in cost control and payroll.
- To maintain good communications with other departments.
- College degree is required.
- Three year of this field experience.
- Must have the proven ability when working with confidential information.
- Must be able to write legibly, complete detailed paperwork and use a computer for extended periods of time.
- Must be well organized.
- Previous hospitality experience preferred.
- Microsoft Office knowledge required.
- Must present a well-groomed appearance.
- Ability to communicate fluently in the Vietnamese language of the workplace and in English both verbally and non verbally.
- Capacity to foster productive relations with peers and assure teamwork is the prevailing way to do business.
- Excellent guest service skills. Must have the ability to respond to handle difficult or stressful situations with tact and diplomacy.
Lĩnh vực làm việc :
Khách sạn/ Khu căn hộ
Nơi làm việc :
Bà Rịa - Vũng Tàu
Thời gian làm việc :
Hành chính
Ngành nghề :
Buồng/ Kho vải/ Giặt là/ VSCC/ Làm vườn
Cấp bậc tối thiểu :
Trợ lý, thư ký
Mức lương :
Thỏa thuận
Số lượng cần tuyển :
Hạn nộp hồ sơ :
Nhận hồ sơ ứng viên bằng:
Tiếng Việt/ Vietnamese
Thông tin liên hệ
Người liên hệ :
Human Resources Department
Email :
Địa chỉ :
Phuoc Thuan Ward, Xuyen Moc District, Ba Ria Vung Tau
xin lưu ý :
Ghi rõ "Biết đến tin tuyển dụng tại Hoteljob.vn" khi nộp hồ sơ cho chúng tôi. Xin cảm ơn!
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Assistant Housekeeping Manager
MGM Grand Ho Tram tuyen dung
MGM Grand Ho Tram tuyen nhan vien
Đánh giá:
Bắt đầu: 25/11/2011
Kết thúc:
The hotels and casinos of MGM Resorts International are among the most famous and spectacular destinations in the world. The key to the success of MGM Resort's renowned brands is the exceptional guest experience we deliver. And that demands passionate, energetic people in such areas as Food & Beverage, Hotel Operations and Gaming Operations. MGM Grand Ho Tram is the first of five resorts being developed by Asian Coast Development (Canada) Limited on the Ho Tram Strip in Vietnam, and will be managed by MGM Hospitality. The MGM Grand Ho Tram will be a luxury integrated resort located approximately 127 kilometers southeast of Ho Chi Minh City. The resort will initially offer 541 luxury guest rooms, a full spectrum of world-class restaurants and amenities, exquisite VIP accommodations, a conference center and a spectacular gaming area for foreign guests. MGM Grand Ho Tram is currently under construction and expected to open in 2013. To prepare for our opening, we are building our team. The following are just some of the many opportunities we have available to work for our prestigious property. If you have the talent and the passion for the service excellence we seek, there's nothing more rewarding than working with MGM Grand Ho Tram, Viet Nam
Địa chỉ: Phuoc Thuan Ward, Xuyen Moc District, Ba Ria Vung Tau
Tel/Fax: +84 64 378 8888
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0983 52 99 55
091 949 0330
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Chăm sóc KV Miền Nam
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Ms. Thanh Hồng
Chăm sóc KV Miền Bắc


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Earlier this week, the Michigan Senate passed anti-bullying legislation that included an exception that allowed religious nuts to bully gay kids if they wanted to. The Michigan Senators who voted for the bill wouldn't characterize it that way, but let's just say those jackasses won't be hosting the Oscars, either.
Yesterday, the Michigan House also passed anti-bullying legislation. This time, there wasn't an exception for those who want to pick on gay kids. House Republicans and Democrats joined on the bill.
As a person who isn't a fan of anti-bullying legislation in the first place, I've kind of been looking at the developments this week with a feeling of: "You see what happens, Michigan?"
One of the problems with trying to regulate personal behavior is that you often end up with an overbroad, unenforceable definition of the behavior you are trying to stamp out.
The Michigan Senate got itself in trouble because, in a fit of homophobia, they wanted to narrow "bullying," which could mean just about anything, so that it was still okay to tell gay kids: "Just FYI, my God thinks you shouldn't be gay and that you are going to hell." They didn't want to make a common statement of
poorly interpreted religious storytelling and fear mongering fact punishable under anti-bullying statutes. Homophobic people don't think bullying gays is "bullying."
Of course, making an exception for gay bullying would render the entire law unenforceable anyway. Some kids get bullied for being gay — but many, many more kids are bullied for "acting gay." Or "looking gay." Or nervously talking to a girl "like you're gay." If I were a bully in Michigan under the state Senate's rules, I'd just claim I gave a kid a good thumping because I perceived he was "turning gay" and I was trying to put him back on course.
So clearly the state Senate was out to lunch and let their own prejudices get in the way of sound policy-making. This would have been a great time for the House to inject some sanity back into the conversation. Unfortunately, they came up with this statement in the Detroit Free Press:
"For many years, people have agreed that bullying is wrong and something needed to be done, but they couldn't find the compassion to compromise, temper their demands and focus on the kids," said House Speaker Jase Bolger, R-Marshall. "Bullying is wrong. It doesn't matter who you are, who you are bullying or why you are doing it."
Be careful with your absolutes there, Speaker Bolger. The lesson from the state Senate should have been that not everybody agrees on what defines "bullying."
Everybody acts like they know bullying when they see it. But what a lot of soccer moms call bullying, a lot of capitalists or biologists might call survival of the fittest. All throughout junior high school, whenever I tried to talk to a girl, some kid would do something to make fun of me. Throw something at me, bump into me on purpose, pull my pants down. These things sucked. At the time, I felt "bullied."
When I grew up a little more (and yeah, by "grow up," I mean "was exposed to an advanced class on natural selection" cause I was a nerd), I learned that the kids weren't "bullying" me; they were competing with me for access to females. Suddenly, everything made sense. It wasn't personal, it was business. Fast forward a freshman week at college and I want to hit on a girl who is being occupied by another guy. I do everything I can to humiliate him and when he doesn't stand up for himself, I (and the girl) realize he's no threat.
And sure, that girl ended up going home with one of my new roommates because I didn't protect my flanks the way I should have, but the point is that if I lived under the Michigan House anti-bullying plan, the original guy would have called the cops as he was being bullied off his mark.
Kids will compete. They will try to get the best of other kids. They will try to destroy those they perceive as threats. Hasn't anyone in Michigan read Lord of the Flies?
You can try, but you can't legislate competition out of mammalian children.
Michigan anti-bullying law protects religious bullies [Washington Post]
Michigan House OKs anti-bullying bill without ifs or buts [Detroit Free Press]
Earlier: Bullying Shouldn't Be A Crime, No Matter How Many Kids Kill Themselves Because of It
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subset: commoncrawl


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Brussels. The European Union is weighing the possibility of forcing tobacco companies into packaging cigarettes without prominent branding, a spokesman said Thursday, hours after Australia's highest court ruled that the approach is legal.
"We are working on a proposal to revise the tobacco products directive. Many things are being discussed, including the possibility of plain packaging," European Commission spokesman Antony Gravili told reporters in Brussels.
The proposal is expected to be brought forward in October or November, Gravili said. It would have to be approved by EU member states and the European Parliament in order to become law.
"We are still very much at the start of the thought process.
There's nothing concrete at this point," Gravili noted. "We are looking at a whole range of things." In Australia, legislation approved last year and set to take effect in December would require cigarettes to be sold in almost identical olive-green packs bearing gruesome photographs of the health effects of smoking.
Gravili noted that another option under consideration is to require such dissuasive images to be larger in the EU.
On Thursday, Australia's high court dismissed a challenge by tobacco firms who argued that the country's anti-smoking initiative broke trademark laws.
Deutsche Presse-Agentur


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Brown Sugar Oatmeal Pancakes Recipe
- 1/2 cup plus 2 tablespoons quick-cooking oats
- 1/2 cup whole wheat flour
- 1/2 cup all-purpose flour
- 1/2 teaspoon baking soda
- 1/2 teaspoon salt
- 1/3 cup packed brown sugar
- 1 egg
- 2 tablespoons vegetable oil
- 1 cup buttermilk
- In a small bowl, combine the oats, flours, baking soda, salt and sugar. In another small bowl, beat the egg, oil and buttermilk. Stir into dry ingredients just until moistened.
- Pour batter by 1/3 cupfuls onto a greased hot griddle. Turn when bubbles form on top; cook until the second side is golden brown.
- Freeze option: Freeze cooled pancakes between layers of waxed paper in a resealable plastic freezer bag. To use, place pancakes on an ungreased baking sheet, cover with foil and reheat in a preheated 375° oven 5-10 minutes. Or, place a stack of three pancakes on a microwave-safe plate and microwave on high for 1-1/4 to 1-1/2 minutes or until heated through. Yield: about 10 pancakes.
Reviews for Brown Sugar Oatmeal Pancakes
Sort By :
"Delicious! I did swap out the all purpose flour for buckwheat flour and added a handful of pumpkin seeds, but otherwise made them as written. Definitely tasty enough to forgo the syrup, and very filling."
"The recipe only made 5 pancakes, which was just right for 3 people. They were very filling. They turned out a little dense and dry - I recommend adding more liquid as some others have suggested. Not too sweet, thankfully, because they needed maple syrup for moisture. I will probably look for another pancake recipe to try."
"My family made faces when I told them what I was making. Now, these are the only pancakes they want to have!"
"These are awesome!! Very filling, great tasting pancake. I did find that buttermilk made them almost too thick so I use 1 T lemon juice in 1 C of regular milk. Plan to try adding vanilla as some have suggested and maybe a few chocolate chips. Yum!"
"I make these about 2 times a week. They are delicious and very filling. I leave out the brown sugar and add a little more than 1/4 cup of Craisins and also add 1 teaspoon of vanilla. I have also made them with the brown sugar included, great this way too, but they do brown quicker. They are wonderful served with real Maple syrup!!!"


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COLUMBIA — A fourth sheriff in less than three years is facing criminal charges in South Carolina.
The State grand jury indicted Chesterfield County Sheriff Sam Parker late Tuesday on four counts of misconduct in office and two counts of furnishing contraband to inmates. Each charge is a misdemeanor, carrying up to 10 years in prison.
Parker used state inmates to work on his home and personal property, and in exchange he allowed the inmates to live outside jail, go shopping and eat out at restaurants, prosecutors said.
Authorities did not detail what kind of work the inmates did or how often they were allowed out from behind bars.
A message left for Parker after hours Tuesday was not returned. A sergeant at the sheriff's office said he had not heard of the charges.
State Attorney General's Office spokesman Mark Powell said that as far as he knew, Parker remained sheriff Tuesday evening in Chesterfield County.
Parker is a veteran lawman, having worked for the Chesterfield County Sheriff's Office before taking a job with the S.C. State Law Enforcement Division. He was first sworn in as sheriff in 2003.
Three of the four South Carolina sheriffs who have recently faced criminal charges have been accused of misusing state inmates.
Former Saluda County Sheriff Jason Booth pleaded guilty to misconduct in office last year for using an inmate to build a party shed and other items on his land. Booth paid a $900 fine.
Former Abbeville County Sheriff Charles Goodwin admitted he took kickbacks on repairs on county vehicles and used a state inmate to do personal work, and was sentenced to five years of probation in January.
Former Lee County sheriff E.J. Melvin was arrested in May 2010 and is serving 17 years in federal prison for drug conspiracy and racketeering.
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Today begins the final two months of the Democratic majority in the House, and the large majority in the Senate. Today, two Democrats, Chris Coons and Joe Manchin, will be sworn in as Senators, while Mark Kirk's swearing-in must wait, under Illinois law, until the certification of his election, which will happen later in November. Roland Burris stays a Senator until that time, so for the moment, the split remains 59-41, and will stay that way through Thanksgiving.
So what do Democrats plan to do with that majority, as well as their 255-178 spread in the House? Not a heck of a lot. The lame duck session will be dominated by talk about what to do on the Bush tax cuts, but there are some other issues that are likely to get taken up as well. Since I wrote about the possibilities for the lame duck when the last session ended before the midterms, the focus has narrowed a bit. Let's go over it.
• Bush tax cuts: We know the battle lines here. Democrats want to extend the tax cuts for the middle class, while Republicans want them extended for all tax brackets. They also want the additional tax cuts, like the ones to dividends, the estate tax rates, and a variety of others, set back at Bush-era levels. The terrain where Democrats and Republicans disagree costs about $700 billion dollars, but overall we're arguing arguing whether to blow a $3 trillion or $4 trillion dollar hole in the budget. For reference, the ENTIRE BOWLES-SIMPSON CATFOOD COMMISSION REPORT gets a savings of $4 trillion. Yet "pass nothing on taxes for the next two months" wasn't their preferred recommendation.
It looks like Democrats don't have the votes to pass tax cuts for the middle class only, and the Republicans certainly don't have the votes to get the tax cuts for the rich made permanent. The meet-in-the-middle here looks like a 2 or 3-year extension, which even Jim DeMint floated this weekend. But that is in no way a "compromise," as it gives Republicans everything they want and sets up for another fight down the road on an issue where Democrats have already given ground. . . .
• Expiring measures: The government must pass a spending bill, either as a stopgap or something more, by December 2nd, to avoid a shutdown. The argument is over how long the stopgap will last. Nancy Pelosi wants to fund with a continuing resolution through the fiscal year, to September 30, 2011. Republicans want a shorter stopgap, so they can get a whack at setting spending levels when they take over the House.
There are also a host of other expiring measures that Democrats will try to take up. Unemployment benefits beyond 26 weeks will start to expire unless Congress passes an extension by the end of the month. This wouldn't include any help for the "99ers," but would merely allow the extended benefits currently in place up to 99 weeks to continue at a time of mass unemployment. It's very iffy whether the Senate can get that done. In addition, the "doctor's fix" and a host of tax extensions expire by the end of the year, so we'll see if the tax extenders bill gets revived to deal with that.
• Food safety: This is actually the bill with the most likely chance of passage. Harry Reid already filed cloture on it and two other bills to start off the lame duck session. The other two, on electric vehicles and paycheck fairness, are actually not expected to pass. But the food safety bill, which received a unanimous committee vote last year, has a good chance of getting done. The cloture vote is likely on Wednesday. The bill would increase plant inspections and give the government more authority to institute recalls. Tom Philpott calls it a small step in the right direction. More important to the members of the Senate, it seems to have the votes, and they can wax eloquently about the bipartisanship it fostered.
• Defense authorization bill: I wouldn't expect to see this until December. That's because the Pentagon survey on Don't Ask Don't Tell won't get released until after December 1, and the defense authorization bill includes DADT repeal. So that means that two Republican votes would need to be secured by that time in order to pass the bill. Several have said that they would want to see the survey before making a decision, including Scott Brown, George Voinovich, Olympia Snowe and Judd Gregg.
If it did pass the Senate, then you'd need a House-Senate conference or some mechanism to iron out the differences, with both chambers passing the same bill, all in December, and it's unclear at this point how deep into the month the session will last. So it's going to be a tall order to get the bill passed.
It's also unclear whether Harry Reid will again try to slip the DREAM Act into the defense authorization bill, or whether he will allow a vote as a standalone measure. As a standalone bill, the DREAM Act actually has a shot at passage; Bob Bennett (R-UT) and Dick Lugar (R-IN) have said they would vote for a standalone bill. I do think you'll see a standalone DREAM Act voted on in the House, perhaps as early as this week.
• The Reid omnibus. The House has passed over 400 bills that the Senate has not taken up. Many of them are noncontroversial in nature. It's possible that Reid will combine hundreds of these noncontroversial bills into an omnibus package, which he will then offer for a vote. Tom Coburn, in the past, has put holds on and tried to block these kinds of omnibus bills, and I can see it being controversial. It will depend on whether the Senate leadership wants to take the time needed to get this through.
• Remainders: I've heard talk about taking one last shot at the DISCLOSE Act on campaign finance reform, and I pretty much don't believe it at all.
The White House has made the new START treaty a top priority, and they're trying to bribe Jon Kyl into giving up on his objections to the treaty by promising spending on so-called "nuclear modernization."
On energy and the environment, outside of the Promoting Natural Gas and Electric Vehicles Act of 2010, which will get a cloture vote this week, I wouldn't expect anything.
Lindsey Graham wants a vote on Chinese currency manipulation, perhaps similar to the House bill that passed right before the midterms.
There are also the looming cat food commission recommendations hanging out there. If they actually get 14 of 18 commissioners to sign off, the Senate and House have basically promised a vote.


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36 People Injured At Avicii Show
It's been a rough year for EDM music, and music festivals. People keep getting injured, or even dying at concerts and festivals. The latest is from Wednesday night in Boston, 36 people were hospitalized after the show. Read about it here
This is the video for Avicii's latest song- Addicted to You


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|« Back to Article
Police arrest man wanted in shooting
By Michelle Mondo : February 18, 2013 : Updated: February 20, 2013 5:13pm
DeVante Jackson, 19, is accused of preventing a man from helping a fatal shooting victim.
More Information
suspect sought in slaying
Devante Jerome Jackson isn't accused of firing the shot that killed Anthony Melvin, but he's been arrested in connection with his death Thursday for allegedly stopping someone from helping the victim.
Jackson, 19, was charged with murder on Monday and given a $100,000 bail, records show.
He was named as the suspected shooter in the police report but is being charged as a party to the crime, according to the arrest warrant affidavit. The affidavit lists the person who shot Melvin as an unknown male.
The motive for the shooting isn't clear.
Jackson and the unknown shooter arrived together at a house in the 2600 block of Corian Drive, then went into the garage with Melvin, 27, and another man, who then lowered the door halfway.
At some point the man with Jackson said, "I don't like the way that white boy is acting," pulled out a gun and pointed it at Melvin, the affidavit states.
The witness tried to get him to put down the gun, but he started firing. During this time, Jackson reportedly slammed the witness against a car and put him in a chokehold and prevented him from helping Melvin, who was hit in the hip, the affidavit said.
As they fled, the man Jackson restrained eventually got his own gun and fired at them. Melvin died in surgery.


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I don't hear Joyce ... | posted Jun 24, 2013 - 2:24:52pm
Joyce when are you going to start some dialog with the European American community about the large amount of crime that is committed against members of the European American community by members of the African American community? Why can we not have some dialog about what is true? Because if you speak the truth you are called a racist.
"While people of color make up about 30 percent of the United States' population, they account for 60 percent of those imprisoned." "Blacks are 39 times more likely to commit a violent crime against whites then vice versa, and 136 times more likely to commit a robbery." NOT MY NUMBERS...YOU TOO CAN LOOK THEM UP JOYCE....
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Pacific Basin Institute's Frank Gibney Talks About the 50th Anniversary Reprinting of His Classic Book
Published in 1953, Five Gentlemen of Japan: The Portrait of a Nation's Character provided a nation with insights into a country and culture that had recently been a mysterious and deadly enemy. Written by Frank Gibney, a former U.S. Navy intelligence officer and now professor of history and president of the Pacific Basin Institute at Pomona College, the classic was reprinted by D'Asia Vu Reprint Library, in December 2003, on the occasion of its 50th anniversary.
Five Gentlemen was the book that "began to inform an entire generation about what had been to many an inscrutable Japan," says Richard Halloran, a former New York Times correspondent in Asia. "Over the years, a few books have equaled it, but none has surpassed it." "Many people remember [the book] as their first introduction to Asia and Japanese society."
"Really a series of snapshots taken at a particular time in history, the book...was extraordinary because it was the really first to describe the Japanese in Japan during and after the war and what they were dealing with," says Gibney. "It was one of the first three or four books about Japan and the Japanese to come out after the war."
The account of "the makers of New Japan" tells the life stories of a journalist, an ex-Navy vice-admiral, a steel worker, a farmer and Emperor Hirohito. In the late 1940s and early 1950s, Japan was a poor, broken and troubled society. Many in both Japan and the West assumed that it would always be so. "But Gibney, who was a wartime intelligence officer and later journalist based in Asia, reported on Japan in such telling detail that readers can see in this book both the now forgotten atmosphere of that time and the basis for the 'Japanese miracle' to follow," explains the publisher. "He reported what it was really like at the time, how places looked, how people felt, what they knew and what they did not."
The author says he hasn't changed his mind about Japan in the intervening years. "Japan remains a very closely knit society of mutual responsibilities, obligations and associations," says Gibney. He does accede however, that "it might have been a bit more measured if I hadn't been 27 at the time."
Five Gentlemen of Japan is one of D'Asia Vu's first three books "partly because it was written so shortly after the war and because so few people knew anything about Japan, while he knew so much, says Douglas Merwin, founder of EastBridge Press (home of D'Asia VU). "The other remarkable thing about the book is that it has held up so well over time."
The goal of the D'Asia Vu Reprint Library is to republish classic books about Asia so that readers can "critically appreciate the range of views and how those views changed over time," explains Merwin. "We put a special focus on books that are effective in the classroom, books that make their many Asias vivid and personal."
Following Five Gentlemen of Japan, Gibney wrote eleven more books, including Korea's Quiet Revolution (1992), The Pacific Century (1992), and Japan: The Fragile Superpower (1975, 3rd ed., 1996). His edited books include Senso: The Japanese Remember the Pacific War (Sharpe, 1995) and, with Col. Hiromichi Yahara, The Battle for Okinawa (1995).
Gibney graduated from the U.S. Navy Japanese Language School and served during World War II as an intelligence officer in the Pacific theater and later in occupied Japan. He left the Navy in 1946 and became a Time magazine correspondent during the American Occupation of Japan. He first came to prominence reporting the Korean War in 1950, when he was Tokyo Bureau Chief for Time. He later edited at Time, Newsweek, and Life, before becoming publisher of Show in 1961. After joining the Encyclopedia Britannica in 1966, he spent ten years in charge of Britannica's business and editorial operations in East Asia. Since 1988 he has been an officer or director of the U.S. Pacific Economic Cooperation Committee.
Over the years, Gibney became a major interpreter of Japan to Americans and America to Japanese, known as a knowledgeable, genial presence in the PBS series "Pacific Century."
In 1979, he established the Pacific Basin Institute in Santa Barbara, California, which has served as a bridge between the United States and East and Southeast Asia for more than 20 years, sponsoring numerous interdisciplinary conferences, workshops and study groups that explore aspects of the growing Pacific community. In 1997, Gibney and PBI moved to Pomona, where the Institute and its unique Asia/Pacific film archive and production facilities play an integral role in the life and academic activities of the college. (More information on the Pacific Basin Institute and its events can be found at http://www.pomona.edu/pbi/.)
Frank Gibney
The Pacific Basin Institute at Pomona College
(909) 607-7467
Email: firstname.lastname@example.com
Douglas Merwin
Publisher, EastBridge Press
(914) 592-8718
Email: email@example.com


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After you establish a virtual private network (VPN) connection with a server, you cannot connect to any shares on the server. You can ping the server by name and Internet Protocol (IP) address, but cannot connect to shares on the server. Net View and Net Use commands fail with one of the following error messages:
System error 121. The semaphore timeout period has expired
System error 53. The network path was not found.
System error 64. The specified network name is no longer available.
This problem occurs because the TCP window size for the TCP connection for the VPN client is 0 (zero).
Service Pack InformationTo resolve this problem, obtain the latest service pack for Microsoft Windows 2000. For additional information, click the following article number to view the article in the Microsoft Knowledge Base:
(https://support.microsoft.com/kb/260910/EN-US/ )How to Obtain the Latest Windows 2000 Service Pack
Hotfix InformationA supported hotfix is available from Microsoft. However, this hotfix is intended to correct only the problem that is described in this article. Apply this hotfix only to systems that are experiencing this specific problem.
If the hotfix is available for download, there is a "Hotfix download available" section at the top of this Knowledge Base article. If this section does not appear, submit a request to Microsoft Customer Service and Support to obtain the hotfix.
Note If additional issues occur or if any troubleshooting is required, you might have to create a separate service request. The usual support costs will apply to additional support questions and issues that do not qualify for this specific hotfix. For a complete list of Microsoft Customer Service and Support telephone numbers or to create a separate service request, visit the following Microsoft Web site:
http://support.microsoft.com/contactus/?ws=supportNote The "Hotfix download available" form displays the languages for which the hotfix is available. If you do not see your language, it is because a hotfix is not available for that language.
The English version of this fix has the file attributes (or later) that are listed in the following table. The dates and times for these files are listed in coordinated universal time (UTC). When you view the file information, it is converted to local time. To find the difference between UTC and local time, use the Time Zone tab in the Date and Time tool in Control Panel.
Date Time Version Size File name -------------------------------------------------------------- 17-Mar-2003 17:11 5.0.2195.6687 119,024 Afd.sys 20-Mar-2003 09:14 5.0.2195.6602 108,816 Msafd.dll 20-Mar-2003 09:14 5.0.2195.6691 314,704 Tcpip.sys 15-Jan-2003 10:56 5.0.2195.6655 16,240 Tdi.sys 20-Mar-2003 09:14 5.0.2195.6601 17,680 Wshtcpip.dll
Microsoft has confirmed that this is a problem in the Microsoft products that are listed at the beginning of this article. This problem was first corrected in Microsoft Windows 2000 Service Pack 4.
For additional information about how to obtain a hotfix for Windows 2000 Datacenter Server, click the article number below to view the article in the Microsoft Knowledge Base:
(https://support.microsoft.com/kb/265173/EN-US/ )The Datacenter Program and Windows 2000 Datacenter Server Product
Article ID: 817069 - Last Review: February 19, 2007 - Revision: 1.8
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Cancer is a leading cause of death worldwide, accounting for over 560,000 deaths in 2009. Because cancer is a collective term for a variety of diseases resulting from an abnormal cell growth, there are numerous causes and risk factors for cancer. The Cancer Subcommittee was established to better understand and improve cancer surveillance.
In 1998, CSTE passed a position statement, 98-CD-04, to include cancer screening indicators in the National Public Health Surveillance System. Since then, cancer screening indicators have included in the collection of chronic disease indicators, and standardized cancer reporting definitions were emphasized in 2009 with position statement 09-CD-01.
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JANESVILLE — Paul Ryan of Janesville, Wisconsin was on the ballot twice Tuesday, November 6th for some Wisconsin voters. Ryan won one race, and lost the other. Ryan was on the presidential ticket as Republican Mitt Romney's running mate, and also running for re-election in the 1st Congressional District.
On Tuesday night, Ryan appeared at a Janesville watch party via video screen, where he thanked supporters following the announcement of his win in the Congressional race. Many said they were disappointed to see a Romney/Ryan loss Tuesday night.
The Secret Service remained posted outside Paul Ryan's Janesville home Wednesday, November 7th, but with the 2012 elections now over, neighbor Douglas Barrette had already removed his Republican-backing political signage.
Next door, some signs remained Wednesday, as Barrette's neighbors continued to show their Democratic support.
"That's the great thing about our country is that we can have opposing views and still be good neighbors and still get along with each other," Barrette said.
"We noticed that our Obama sign got stolen. I tried to make a sign before I went to be that congratulated Wisconsin on our Democratic victory," Patrick Foelker said.
Foelker said his makeshift sign also shows his appreciation for all those who voted — regardless of candidate choice or party affiliation.
"We all have our own personal views. That's what makes America what it is," Foelker said.
Neighbors told FOX6 News they're anxious to see whether Paul Ryan makes a run for the presidency in 2016.
CLICK HERE for additional presidential election coverage via FOX6Now.com.
CLICK HERE for additional Election Day coverage via FOX6Now.com.


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School menus
LEE COUNTY — Monday: Corndog nuggets or toasted cheese sandwich, corn, green beans, California blend veggies, fresh fruit, mixed fruit; Tuesday: Nachos or turkey and cheese sandwich, manager's choice of vegetable, pinto beans, mandarin oranges, sliced pears; Wednesday: Chicken fajita or pork roast on whole wheat bun, baked beans, coleslaw, sliced peaches, fruit cocktail; Thursday: Hot dog or cheeseburger on whole wheat bun, tater tots, glazed carrots, blueberry cup, applesauce; Friday: Pizza or manager's choice, candied yams, steamed broccoli with cheese, baked apples, pineapple tidbits.
GRACE CHRISTIAN — Monday: Chicken nuggets, mashed potatoes, butterbeans, roll, fruit, milk; Tuesday: Baked ziti with meat sauce, corn, garlic bread, fruit, milk; Wednesday: Pizza, lettuce and tomato salad, fruit, milk; Thursday: Chicken dumplings, green beans, roll, fruit, milk; Friday: BBQ sandwich, cole slaw, baked beans, deli spear, fruit, ice cream, milk.
LEE CHRISTIAN — Monday: Chicken filet sandwich, lettuce, tomatoes, potato chips, fruit; Tuesday: Sausage patties, mac-n-cheese, pinto beans, cornbread muffins; Wednesday: Tacos, lettuce, tomatoes, cheese, sour cream, fruit; Thursday: Chicken parmesan, buttered noodles, lima beans, garlic bread; Friday: Pizza, tossed salad, fruit.


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Local oestrogen therapy: how it differs from conventional HRT
Why might you need local oestrogen therapy?
· At least 50% of women who have been through the menopause suffer from symptoms resulting from changes to their vagina and genital area
· These include:
o Vaginal dryness, soreness, itching or burning
o Vaginal discharge or light spotting of blood
o Discomfort and pain during sex
o Urinary symptoms, such as having to rush to go to the toilet, going frequently or getting up at night more often
o Recurrent urinary tract infections (UTIs)
o Rubbing, discharge or discomfort when using pessaries to treat a prolapse
Why does this happen?
· The female hormone oestrogen, produced by the ovaries, is important in keeping the tissues in and around the vaginal area healthy, supple and moist. It helps the lining of the vagina remain thick and elastic whilst maintaining the right environment to fight infection
· After the menopause, the ovaries stop producing oestrogen so the amount of hormone in a woman's body decreases
· This can lead to the tissues in this area becoming thin, dry, less elastic and generally more delicate
· The vagina & bladder may also be more prone to infection after the menopause
· The combination of these changes is sometimes called vaginal atrophy or atrophic vaginitis
By replacing the oestrogen directly to the vagina, it is possible to reverse some of these changes by restoring the tissues in this area
Are there different types of local oestrogen therapy?
· Yes!
· The most popular type is a slow-release vaginal tablet. This is commonly known as Vagifem. It is a low dose natural oestrogen, which is easy and hygienic to use. One pea-sized tablet is inserted into the vagina using a small disposable applicator. This is usually given every day for the first 2 weeks, and then twice a week for about 3 months
· Vaginal oestrogen creams, such as Gynest, are another way of delivering oestrogen directly to the tissues that need it but some people find it a little more 'messy'
· All types of local oestrogen therapy are equally effective for treating your symptoms
How long does it take to work?
· Most women find that their symptoms start to improve within 2 weeks but to get the full effect takes a couple of months, so persevere!
What is Hormone Replacement Therapy (HRT)? Aren't there risks associated with taking HRT, such as breast cancer?
· HRT is a way of replacing oestrogen, and another hormone called progesterone, once the ovaries stop producing them
· HRT is commonly given as oral tablets or patches on the skin
· It is usually given to reduce menopausal symptoms such as hot flushes and vaginal atrophy as well as protecting women against bone thinning
· There is some evidence that taking HRT for a long time gives women a small increased risk of blood clots in the legs and developing cancer, such as breast cancer
How is local oestrogen therapy different?
· Local therapy supplies oestrogen to the vagina and surrounding areas without giving it to the whole body
· It is delivered directly to the tissues that need it, so lower doses are needed
· Only a very small amount is absorbed into the blood stream and so has less of an effect on the rest of the body. This decreases the risks associated with hormone treatment to almost zero
· Local oestrogen therapy has a similar effect on vaginal and urinary symptoms as systemic (oral) oestrogen therapy but will not help hot flushes, mood swings, night sweats etc.
Because a very small amount of oestrogen is absorbed into the blood stream, manufacturers have traditionally said on the data sheets that local oestrogen therapies carry the same risks as other forms of HRT and so carry the same warnings. There is however no evidence to support this, and for newer preparations, such as Vagifem, the information leaflets are less prescriptive.
How long can I use it for?
· In the UK, vaginal creams are licensed for 3-6 months of continuous use. For Vagifem, this has now been extended to indefinitely at the recommended dose.
What are the side effects of local oestrogen therapy?
· Small amounts of hormone in the blood stream may cause oestrogen-related side effects such as breast tenderness
· Some women experience irritation around the vagina
Who should avoid using oestrogen tablets or creams?
· Women who currently have oestrogen-dependent cancers, such as breast or uterine cancer
· Women with a past history of breast cancer, angina or blood clots in the legs should seek
specialist advice
· Women who are having investigations for post-menopausal bleeding (bleeding from the vagina after having stopped periods) should delay using them until a cause has been found. Local oestrogen may however be a treatment for this in many cases.
Oestrogen – a female hormone, produced by the ovaries
Progesterone – another female hormone produced by the ovaries, which is not contained in local oestrogen therapy
Menopause – commonly known as 'the change'. This is when the ovaries stop producing hormones, such as oestrogen. It happens at around age 50 and is associated with symptoms such as hot flushes and vaginal dryness and soreness
HRT – Hormone Replacement Therapy. This is a way of giving oestrogen and progesterone to the whole body to reduce the symptoms associated with the menopause


text: So my best friends mom has been told for several years they think she has Lupus..several symptoms, but never positive blood work. Not knowing what else it was I am sure. (diagnosis by default) She has taken very good care of herself,and recently, has not been feeling well.Long story short, cardiologist and pulmonologist batted her back and forth..to no avail( she had breathing issues) .She got an appointment with the head of Rheumatology at Columbia Presbyterian Hosp NYC. He was shocked a previous doc told her Lupus, and he did some serious testing for vasculitis..DX Giant Cell Ateritis..very serious. From what I've read it can be part of Lupus...anyone have this?


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Ron Vander Kelen - 1968 Topps #125
Rookie card
Vander Kelen played for the Vikings from 1963 to 1967. The Vikings traded him to the Falcons in 1968, but he did not play a regular season game for the Falcons. Vander Kelen and Pete Beathard were the MVPs of the 1963 Rose Bowl, in which #1 USC beat #2 Wisconsin 42-37.
Estimated value: ex $2, nm $5 explain
Player: Ron Vander Kelen
Pro Team: Atlanta Falcons
Position: quarterback
College: Wisconsin
Hometown: Green Bay, WI
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Last week, GoGrid announced its "any cloud" orchestration engine service, enabling telcos to deliver complex, on-demand solutions, multi-cloud support, and data sovereignty compliance. We received an overwhelmingly positive response to our pioneering technology and unique approach.
But don't just take our word for it. Check out what Light Reading (the premier publication for the telecom industry) had to say in its story, "GoGrid Puts Cloud at a Touch of a Button." As reported by Carol Wilson, the article underscores the reasons why orchestration is so attractive to telcos:
"The attraction is taking the complexity out of provisioning applications, and while GoGrid is initially focused on big data apps, this approach can support other kinds of applications as well, says Caroline Chappell, senior analyst with Heavy Reading. Telecom cloud service providers have been trying to develop this capability themselves so they can offer business customers the ability to stand up a whole range of applications in the cloud without individually engineering each one through a complex process, she says.
"Telecom cloud providers can make the provisioning process part of the service they offer, even if the application itself is run by an app partner in a third-party cloud, Chappell notes. That creates the ability for telecom cloud providers to offer a cloud-based "business in a box" type offer that doesn't require complex provisioning of each individual service."
Orchestration is key for telcos to quickly and easily increase the variety and number of products they offer. It also keeps them focused on what they do best: selling solutions wrapped with value-added services instead of commodity infrastructure. Click here to learn more about GoGrid's orchestration and 1-Button Deploy™ solutions.


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I am the Programme Manager on Food, Agriculture and Rural Development of IBON International. I also provide secretariat support to the People's Coalition on Food Sovereignty (PCFS), a global grassroots groups of small food producers promoting food sovereignty as a campaign and advocacy platform which is currently hosted by IBON.
The FSN Forum is supported by the project Coherent food security responses: incorporating right to food into global and regional food security initiatives.


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A judge's decision Wednesday not to block a voter ID law in Pennsylvania could make the Keystone state — which tends to slightly lean to Democratic Party candidates — a possible key pick-up for Republican presidential candidate Mitt Romney. See the ruling.
Obama at the moment has a 7-point lead in polls of the state, according to the RealClearPolitics average.
A study by the state estimates that about 9% of 8.2 million registered voters do not have a Pennsylvania Department of Transportation issued license. Some of that 9% of course hold other valid ID, like a passport, and Pennsylvania already has taken steps to make it easier for those with lapsed driver's licenses to get new ID.
The impact of some of that 9% not being able to vote is what's in the air. Famously, the head of Pennsylvania's state House Republicans, Mike Turzai, said in June: "Voter ID, which is gonna allow Governor Romney to win the state of Pennsylvania, done."
Turzai was more restrained Wednesday. "The elections in the Commonwealth will be on a more level playing field thanks to voter ID and other recent election reforms," he said in a statement.
The law still could get blocked. The Pennsylvania Supreme Court — which currently consists of three Democrats and three Republicans — almost certainly will hear the case; a majority would be needed to overturn the ruling. Federal lawsuits also are possible.
– Steve Goldstein


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If you are looking for rider support, we are looking for you. There are many levels of support offered, we are helping top level pros as well as the novice rider. We are looking for all different skill levels, all different venues, and different brands of bikes.
Send your resume with race results to:
Precision Concept Racing
6236 Rivercrest Drive Suite I
Riverside, Ca. 92507 or Email Us
Mobile Site


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Recent News Articles
South High Botany Students Visit Christopher Farm and Gardens
South High School Botany classes recently visited Christopher Farm and Gardens along the western shores of Lake Michigan in the scenic Pigeon River Valley of Mosel Township. Christopher Farm & Gardens consists of approximately 400 acres with over 6,000 feet of shoreline on Lake Michigan in which the students participated in learning about various types of plant life and growing conditions, as well as landscaping techniques including vertical gardening.
Sheboygan Area School District Press Release
December 10, 2012
December 10, 2012


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News Releases by Email
News Release
Thursday, March 21, 2013
Media contact: Jeff Summers, 386-758-0525
The Florida Fish and Wildlife Conservation Commission (FWC) has lifted boating restrictions on the Santa Fe River, Zone 5. On Wednesday, the river fell below 17 feet at Three Rivers gauge, which meant the FWC could deactivate the zone's restrictions and allow boaters using the river to resume normal operating speeds.
Idle-speed, no-wake restrictions on Zone 5 – a 32-mile segment from River Rise in O'Leno State Park west to the confluence of the Suwannee River – were activated March 3, when the Santa Fe River reached 17 feet on the Three Rivers gauge, where flood stage is 19 feet.
For more information about the flood zones, please call 386-758-0525. To report violations, please call 888-404-3922.
To obtain real-time river level information, visit MySuwanneeRiver.com.
FWC Facts:When divers are out of the water, a dive flag may not be displayed.
Learn More at AskFWC
Get FWC News Feeds
Florida Fish and Wildlife Conservation Commission • Farris Bryant Building
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Roy: 'My Basketball Days Are Numbered'
by Jesse Dorsey
In case there was any doubt left, Brandon Roy has all but confirmed that he's done playing basketball in the NBA . Roy played for the Minnesota Timberwolves this past season, although that's a bit... Read More »
What Brandon Roy Meant to the Blazers and Their Fanbase
by Alex Tam
For five seasons, Brandon Roy dazzled and awed Portland Trail Blazers fans with his late-game heroics that turned him into a bona fide NBA superstar... Read More »
Report: Wolves to Release Roy
by Brian Mazique
The Minnesota Timberwolves have given up on Brandon Roy as a reclamation project, according to the team's public relations Twitter account: It is a logical move for the organization as it i... Read More »
Oden's Comeback Ignores Roy Struggles
by Will Carroll
Greg Oden is getting closer to a comeback. How close is up for debate. At least four teams have made informal offers, while several others have checked in just to see where the former No... Read More »
Will Brandon Roy's Mystery Treatment Give Kevin Love the Help He Needs?
by Maxwell Ogden
Adrian Wojnarowski of Yahoo! Sports reported on December 29, 2012 that Brandon Roy would attempt to continue his injury-plagued NBA career by seeking further treatment... Read More »


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August 4, 2015
NEW YORK (AP) - San Antonio Spurs guard Tony Parker is suing a New York City club and its operators for $20 million over a scratched retina he says he suffered during a fight involving singer Chris Brown and members of hip-hop star Drake's entourage.
The suit was filed in State Supreme Court in Manhattan on Thursday. It says the W.i.P club in SoHo and its operators were negligent in security and supervision, which allowed the fight to take place.
Chris Brown, his girlfriend and his bodyguard were among eight injured during the fight inside the club last week. Police say members of Drake's entourage stopped Brown as he was leaving. The fight escalated and bottles were thrown.
There was no answer at phone numbers listed as affiliated with those named in the lawsuit.
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Parking valet on demand
Queena Kim
Oct 24, 2014 In the "instant gratification" economy, even parking has an app.
How techies are reenvisioning restaurants
Queena Kim
Sep 29, 2014 Hungry? There's an algorithm for that ...
Tech IRL: Apps to get lost in familiar places
Raghu Manavalan
Aug 23, 2014 Marketplace Tech host Ben Johnson talks about a few apps that help you discover a neighborhood and city instead of get from point A to point B.
Silicon Tally: Pizza pushers
Ben Johnson
Aug 22, 2014 How well have you kept up on this week's tech news?
'Sup: The new Yo?
Kai Ryssdal
Aug 12, 2014 Novelty apps are turning over at a ferocious pace. What could go wrong?
Uber ranks drivers... and passengers
David Gura
Jul 28, 2014 For a second there, passengers could find out how they rated.
Using apps to track cattle in Scotland
Ben Johnson
Interview by
Feb 5, 2014 A look at the app designed by Scottish teenagers to help track cattle.
Facebook launches Paper app
Ben Johnson
Interview by
Feb 3, 2014 The new iPhone app seeks to streamline the experience of reading Facebook.
Talking turkey with a techie
Ben Johnson
Interview by
Nov 27, 2013 Scott Heimendinger of the Modernist Cuisine cookbooks talks Thanksgiving and Modernist Cuisine's new cookbook app with Marketplace Tech.
Don't want to wait in line for the new iPhone? There's an app for that.
Conrad Wilson
Sep 20, 2013 With the launch of the iPhone 5s on Friday, a look at placeholder services that offer to stand in line for you in exchange for a fee.


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Method for administering dipeptides and tripeptides to mammals for dietary purposes, orally, intragastrointestinally and intravenously. The tripeptides and dipeptides, contain glycine as the amino acid residue which provides the N-terminal amino acid grouping. Other amino acid residues contained in the tripeptide or dipeptide can include leucine, isoleucine, valine, threonine, methionine, phenylalanine, lysine, tryptophan, alanine, arginine, histidine, alanine, proline and glutamic acid.
1. A nutrient composition comprising an aqueous solution containing from one to 20 weight percent of at least two oligopeptides selected from the class consisting of dipeptides and tripeptides,
wherein the said oligopeptides include a single glycine unit which is the N-terminal amino acid residue of the oligopeptide.
2. A nutrient composition of claim 1 wherein the said tripeptides are selected from the class consisting of: Glycine-leucine-leucine, glycine-isoleucine-isoleucine, glycine-valine-valine, glycine-threonine-threonine, glycine-methionine-methionine, glycine-phenylalanine-phenylalanine, glycine-lysine-lysine and glycine-tryptophan-tryptophan.
3. A nutrient composition of claim 1 including other nutrients selected from the class consisting of fats, glucose, oligosaccharides, minerals, trace elements and vitamins.
4. A nutrient composition of claim 1 including oligopeptides having amino acid residues of all the essential amino acids.
5. A nutrient composition including the composition of claim 4 and at least one oligopeptide of non-essential amino acids.
6. A nutrient composition of claim 1 wherein the said dipeptides are selected from the class consisting of: glycine-isoleucine, glycine-leucine, glycine-lysine, glycine-methionine, glycine-phenylalanine, glycine-threonine, glycine-tryptophan and glycine-valine.
7. A method of administering a nutrient composition to a living mammal which comprises orally introducing into the said mammal the aqueous solution of claim 1.
8. The method of administering a nutrient composition to a living mammal which comprises parenterally introducing into said mammal the aqueous solution of claim 1.
9. The method of administering a nutrient composition to a living mammal which comprises intragastrointestinally introducing into said mammal the aqueous solution of claim 1.
10. The method of administering a nutrient composition to a living mammal which comprises intravenously injecting the aqueous solution of claim 1 into a periperal vein of said mammal.
11. The method of administering a nutrient composition to a living mammal which comprises merging a stream of the aqueous solution of claim 1 with a stream of another aqueous parenteral solution and injecting the resulting merged stream intravenously into the said mammal.
12. The method of claim 7 wherein the said living mammal is a living human.
The invention described herein was made in the course of work under a grant or award from the Department of Health, Education and Welfare.
This application is a continuation-in-part of my co-pending U.S. patent application Ser. No. 130,309 filed Mar. 14, 1980, now abandoned.
1. Field of the Invention
This invention relates to nutrient compositions for mammals and more particularly to nutrient compositions containing oligopeptides and methods of administering them to mammals.
2. Description of the Prior Art
Man and other mammals require protein daily to satisfy vital functions. Proteins are converted to amino acids in the digestive system and the resulting amino acids are employed by the body for growth, development, multiplication and metabolic functions. The human body requires a daily supply of the essential amino acids which are lysine, leucine, isoleucine, tryptophan, methionine, valine, phenylalanine, and threonine. There are other amino acids, called "non-essential," which the body employs as a source of nitrogen. The non-essential amino acids are alanine, glycine, serine, proline, histidine, tyrosine and cysteine.
In the absence of the essential amino acids, there is a rapid deterioration of the nutritional state which results in dysfunction of practically every organ in the body with consequent health problems such as liver failure, anemia, infection, diarrhea and retarded growth.
In the absence of protein or in circumstances where a medical patient is unable to assimilate protein, it is possible to supply free amino acids intravenously and intragastrointestinally as a solution. Elemental diets which were popular in the practice of medicine in the 1970's employed such solutions of free amino acids. These solutions are hypertonic. Hypertonic solutions, whether in the intestines or in the blood vessels are not well tolerated and may cause undesirable effects such as diarrhea and dehydration. These problems may be critical in sick patients.
While the body can matabolize amino acids, the body's transport system can more effectively utilize peptides which can be absorbed and thereafter hydrolyzed within the body's cells to amino acids.
More recent discoveries have indicated that the human digestive system includes separate sites for absorption of dipeptides and absorption of tripeptides in the intestinal mucosa. When absorbed, the dipeptides and tripeptides are hydrolyzed into constituent amino acids. The hydrolysis thus occurs after the peptides are within a body cell. See Adibi and Soleimanpour, J. Clin. Invest. 53: 1368-1374 (1974).
The peptide transport system has the following features:
(a) It does not take up amino acids, but instead transports dipeptides and tripeptides.
(b) It has little or no affinity for peptides with more than three amino acids residues.
(c) It has higher maximum rate of uptake than an amino acid carrier system.
(d) It prefers peptides with lipophilic amino acids in the N-terminal position.
(e) Its greatest activity is in the jejunum and its least activity is in the duodenum with the ileum being between these extremes.
The elemental diets employing free amino acids are usually hypertonic. The hypertonicity creates secondary problems in medical patients with gastrointestinal disorders.
There are reports of the administration of a single dipeptide or a single tripeptide for academic clinical evaluation.
However today there remains a problem of supplying adequate amino acid nutrients to a mammal such as a human medical patient, in a form where the amino acid content can be assimilated by the transport system without the adverse effects of hypertonicity.
According to the present invention, a nutrient composition is provided which is an aqueous solution of oligopeptides (dipeptides and/or tripeptides) wherein each of the oligopeptides has a glycine residue as the N-terminal amino acid grouping. The aqueous solution of oligopeptides can be supplied at twice (in the case of dipeptides) or three times (in the case of tripeptides) the concentration of amino acids at the same osmolality as a corresponding solution of free amino acids. Moreover the oligopeptides are readily assimilated by the transport system and readily converted to amino acid residues. Within the body cells, the oligopeptides of this invention have a glycine grouping as the N-terminal grouping of the oligopeptides. The glycine terminated oligopeptides achieve a desirable intact transport of the oligopeptide into a cell. The glycine grouping protects the oligopeptide from hydrolysis into amino acids by the peptidases on a cell membrane. Premature hydrolysis of the oligopeptide into amino acids would upset the osmolality of the system. The glycine grouping is also lipophilic and the oligopeptide has an enhanced transport through the cell membrane. The oligopeptide can be cleaved into its component amino acids inside the body cell.
The glycine-terminated oligopeptides are particularly water-soluble which permits the use of such oligopeptides in high concentrations. This feature is of special importance in treating patients having a restricted-water diet, e.g., certain heart patients and kidney patients. The glycine-terminated oligopeptides have good thermal stability which permits the autoclaving of such materials for sterilization. The glycine-terminated oligopeptides in solution also have good shelf-life stability.
The oligopeptides may be administered intravenously, along with other nutrient compositions such as fats, glucose, saccharides, minerals, trace elements and vitamins. The oligopeptide solution may be introduced orally or by other intragastrointestinal administration techniques, e.g., stomach tubes and insertion tubes elsewhere in the intestinal tract.
The oligopeptide solution contains from about one to twenty percent by weight of the oligopeptides, preferably about one to five percent by weight. The aqueous solution may be an electrolyte solution suitable for intravenous feeding or for intragastrointestinal administration. The aqueous solution itself may contain the other nutrient additives such as fats, glucose, mono- or oligo saccharides, minerals, trace elements and vitamins.
Aqueous dietary compositions are prepared which include at least two tripeptides or at least two dipeptides or mixtures containing at least one dipeptide and at least one tripeptide. The term oligopeptide, as used herein, includes dipeptides and tripeptides. The oligopeptides include a glycine residue and one or two other essential amino acid residues such as lysine, leucine, isoleucine, tryptophan, methionine, valine, phenylalanine, threonine; or non-essential amino acids such as arginine, histidine, alanine, proline and glutamic acid. The glycine residue is the N-terminal residue in the oligopeptide.
The concentration of the oligopeptide in the aqueous solution is from 1 to 20 percent by weight, preferably from 1 to 5 percent by weight. Aqueous solutions containing about 2.5 weight percent of the oligopeptides have useful biological absorption characteristics. The selection of the oligopeptides in the composition depends upon the requirements for essential and non-essential amino acids.
A typical mixture of tripeptides is set forth in Table 1.
The mixture of Table 1 is intended to approximate one 850-mg. portion of a protein of high biological value. The mixture of Table 1, in one liter of water, comprises a useful nutrient composition.
TABLE 1______________________________________One 850-mg. PortionTripeptides Amount (mg)______________________________________glycine-leucine-leucine 77glycine-isoleucine-isoleucine 59glycine-valine-valine 70glycine-threonine-threonine 53glycine-methionine-methionine 71glycine-phenylalanine-phenylalanine 75glycine-lysine-lysine 57glycine-tryptophan-tryptophan 21glycine-alanine-alanine 367______________________________________
The first eight tripeptides of Table 1 provide all of the essential amino acids. The glycine-alanine-alanine tripeptide satisfies a need for non-essential amino acids.
The structural formula for glycine-leucine-leucine is as follows: ##STR1##
The glycine unit ##STR2## supplies the N-terminal grouping in the tripeptide or dipeptide.
A composition of dipeptides is provided in Table 2 for preparing a one-liter aqueous solution of dipeptides which supplies the human daily amino acid requirements. It will be observed that the dipeptides include a glycine residue which is the N-terminal residue.
TABLE 2______________________________________One liter SolutionDipeptide grams______________________________________glycine-isoleucine 2.5glycine-leucine 3.5glycine-lysine 3.1glycine-methionine 3.2glycine-phenylalanine 3.3glycine-threonine 1.6glycine-tryptophan 0.63glycine-valine 2.5glycine-arginine 5.9glycine-histidine 1.5glycine-alanine 5.4glycine-glutamic acid 6.9glycine-proline 5.8______________________________________
The aqueous oligopeptide solution may be ingested orally along with other nutrients such as conventional foods of prepared vitamins, fats, glucose, oligosaccharides, minerals and trace elements. For parenteral administration, a supply of the oligopeptide solution may be merged through a Y-connection with a supply of glucose solution or other parenteral solutions. In appropriate instances, the oligopeptide solution may be mixed with glucose solutions and/or other parenteral solutions to create a mixture which may be administered parenterally.
The same oligopeptide mixture for oral use can also be used for parenteral nutrition. Frequently, in the practice of medicine, situations are encountered in which patients are unable to receive their daily nutrient requirements orally. The development of total parenteral nutrition by Dudrick and colleagues (Dudrick et al, Surgery 64:134-142, 1968) has made possible the intravenous infusion of sufficient energy and essential nutrient requirements. The intravenous solutions currently used are made up of free amino acids which made these solutions hypertonic. Therefore, the solutions must be given through catheters placed in large central veins, frequently considered to be a surgical procedure. Serious complications, such as infection, have been reported to accompany this central vein method of parenteral nutrition. In addition, there could be serious complications as the result of infusion of hypertonic solutions, such as thrombosis of the vein, dehydration, and even coma. The administration of oligopeptides rather than free amino acids allows administration of the same amount of amino acid residue in solutions which are not hypertonic and therefore can be introduced into peripheral veins, which procedure is not considered to be a surgical procedure.
The concentration of the oligopeptides in an intravenous solution should be such that the amino acid composition of the solution is similar to the amino acid composition of the currently-used free amino acid solution which has shown to be satisfactory for maintaining protein nutrition.
The oligopeptides of the present compositions are water-soluble. The composition preferably contains some oligopeptides of non-essential amino acids to supply nitrogen. The composition permits intact transportation of the oligopeptide into the cells followed by intra-cellular hydrolysis.
Intravenous injection of the oligopeptides results in an increase in the insulin output when compared with the output resulting from intravenous injection of corresponding free amino acids. The oligopeptides rapidly disappear following intravenous injection, indicating that they are rapidly utilized. The speed of utilization is particularly rapid with kidney tissue; less rapid with muscle tissue.
Although the invention has been shown in connection with certain specific embodiments, it will be readily apparent to those skilled in the art that various changes in form and arrangement of steps can be made to suit requirements without departing from the spirit and scope of the invention.
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South Carolina goes on the road to face Kentucky today
Frank Martin wouldn't go into detail Saturday on why he accepted the blame for South Carolina's 67-56 home loss to Georgia.
The first-year Gamecock coach said at that time that he didn't do his job well enough, and that he didn't want to elaborate.
Heading into today's difficult road game at Rupp Arena against Kentucky, Martin was more forthcoming as to why he was beating himself up over last week, when the Gamecocks (12-9, 2-6 SEC) also lost by 39 at No. 2 Florida after looking like they'd turned a corner the previous week.
"I talk all the time about not paying attention to winning and losing, paying attention to detail, paying attention to who we are, paying attention to the culture, and we had been playing so good that I got wrapped up with the other team more than our own team," Martin said Monday. "I'm asking our guys to fight every single day for the culture we're trying to build. Well, they've never done that (before), and for me to expect them to do that on their own right now is not fair to them.
"If I don't pay attention to detail, if I don't hold them accountable, if I don't fight for it every day, I can't expect them to do it themselves. We're not there yet as a program. That's what I meant when I said what I said."
Despite shooting below 36 percent in last week's two losses, Martin is more concerned with his team's defensive effort. The Gamecocks allowed 142 points combined against the Gators and Bulldogs.
"After the first seven minutes in the Florida game and the whole Georgia game, our defense was embarrassingly bad, just bad," Martin said. "It's not the defense that we had been playing for three weeks or whatever leading into last week. That's on me. I allowed us to play that way."
He also said that playing teams with length on both the perimeter and on the low block has been a detriment to USC's success this season because it's made it more difficult to pass and set up the offense.
That will be a problem the Gamecocks are likely to run into again today at 9 p.m. on ESPNU at a place where they've only won twice in 26 tries.
Kentucky (15-6, 6-2) is led by a tremendous defensive presence in freshman Nerlens Noel, who swatted 12 shots last week against Ole Miss. His 97 blocks is 40 more than the next best shot blocker in the SEC, and Noel is ranked second in the league with 2.3 steals per game.
"There's not a lot of Nerlens Noels out there. He's a special player and the thing is they just don't have one," Martin said. "They've got two of them, because Willie Cauley blocks shots with the best of them, too."
The defending national champion Wildcats haven't experienced the same kind of success thus far as they did a year ago, but John Calipari's squad is coming off a pair of road wins at Ole Miss and Texas A&M that has UK in better standing.
"I was surprised we were at home this week," Calipari said. "We've been on the road four or five games, I thought we were just a road team. I didn't think we played home games, but it's good to be back."
Five Wildcats average double figures in scoring, and Kyle Wiltjer, who's made 45 3-pointers, is UK's best outside shooting threat on a team putting up 76.2 points per game. Kentucky allows 62.9 per game.
USC is scoring 69.1 points per contest while allowing 67.9 heading into its only regular-season matchup against Calipari's crew.
"Frank's done a good job of putting a team on the floor that's gonna play the best way they can to win games, muck up the game and be really aggressive," said Calipari, whose program has won the last five meetings against the Gamecocks. "And (they) do stuff that they have to do to give them a chance."
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Only 14 percent of the students who attend closing DC Public Schools have re-enrolled in the school system for the fall, schools Chancellor Kaya Henderson said Tuesday.
Only 14 percent of the students who attend closing DC Public Schools have re-enrolled in the school system for the fall, schools Chancellor Kaya Henderson said Tuesday.
The Pontiac school district could be dissolved and students distributed to other districts under legislation being worked on this week in the House of Representatives Education Committee in Lansing.
For now, Chicago Public Schools has legally left the door open to the possibility of halting 10 of its 50 historic school closings, the Chicago Sun-Times reports.
The Albion Public Schools board took its final step to discontinuing teaching high school in its district.
A wealthy school district in Colorado is launching a radical experiment that sets a different pay scale for each category of educator, ensuring that even the best third-grade teacher would never earn as much as a veteran high-school math teacher.
An annual scorecard on the district's performance and greater accountability throughout the system are some of the promises outlined in the first long-term plan for Chicago Public Schools issued since Mayor Rahm Emanuel took office.
Twenty New York City middle schools will add an extra 2.5 hours to the school day of 2,000 sixth-graders starting in September, Schools Chancellor Dennis Walcott and City Council Speaker Christine Quinn said on Monday.
Five years into the second phase of its mission to overhaul America's public schools, the Bill & Melinda Gates Foundation is moving to work more closely with teachers, generating interest but also wariness because of past hostilities.
With two notable exceptions, the 2013 Legislature was marked by the death of a wide range of public school bills, including a push to delay the key impact of Louisiana's new teacher evaluations.
KayLynn McAbee is one of thousands of high school graduates across Colorado slated to take costly remedial courses that do not count toward her college degree. But McAbee will not have to pay for the courses because of a new summer program developed by Denver Public Schools.
Many in Inglewood thought the city's struggling school district had been handed a lifeline last year when the state Department of Education took the reins, hiring new leaders and infusing the school system with $55 million in emergency loans.
When reforms are implemented with little or no input from the community, there is going to be a level of frustration and lack of ownership because there is no buy-in. These conditions do not bode well for the sustainability of any reform, regardless of its intentions.
More than 100 Clark County public schools' ratings were downgraded under Nevada's new school accountability system unveiled Friday morning.
In the past decade, the Seattle School Board chose "discovery math" books for the public schools. The chance to correct these mistaken decisions begins next year with new texts for grades K-5.
The district's new enrollment figure may be inflated, as administrators at some closing schools said that because they were under pressure to get children signed up, they went ahead and enrolled students whose parents could not be contacted.


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Glowy Cheeks with Benefit High Beam
Searching for that dewy, glowy look? Benefit High Beam has you covered!
Benefit High Beam ($24.00) is a liquid highlighter that comes in a small bottle. Twist the cap and you'll see a brush applicator–all in all, the packaging and application system looks very much like nail polish. I've found the best application method is to take the brush and dot it on the areas you want to highlight. I usually dotted two or three small-sized dots on my cheek bones, and then I blended it in with MAC's 188 brush.
High Beam can act as a highlighter or illuminizer, which makes it a great, multi-tasking product to keep in your makeup bag. (Because of the packaging, it also makes a nice travel companion!) To use it as an illuminizer, mix a drop or two with your favorite foundation or moisturizer and apply all over to face. If you've used Strobe Cream, it's kind of like that, but you're able to mix to your desired level of lumination. As a highlighter, you use it on the traditional areas where you'd want light to reflect off your face (cheek bones, forehead, nose, chin, and so on). You can also use this on your brow bone — it is especially nice when you're just wearing mascara, because it helps to brighten and wake-up tired eyes with minimal effort.
The best part about High Beam is that it isn't noticeable that you're wearing makeup. It's subtle, soft, and has just this beautiful dewy, glowy finish that looks incredibly natural and yet adds so much more to your complexion. It doesn't look or feel like a typical shimmery highlighter; it feels more like a radiant highlighter, where the luminous feel comes from a soft sheen instead of sparkles or glitter. I've had both my mom (older than me) and sister (deeper skintone) try this, and it looked equally lovely on them.
- Product: 8/10
- Value: 9/10
- Ease of Use: 7/10
- Packaging: 7/10
Recommendation: If you love dewy skin and are looking for a new highlighting option, consider Benefit High Beam. The product itself is high-quality, they give you plenty of it, and it's fairly easy to use. The packaging is functional and cute, though the applicator system could use improvement. Overall, it's a solid product and worth purchasing.
Availability: BenefitCosmetics.com, Sephora.com
Have you tried Benefit's High Beam? Yay or nay?
See a swatch…
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Posted Date:2011-10-10
Company:SupportSpace Inc
SupportSpace Inc. (US Headquarters - South San Francisco, CA), a leader in third party, remote IT technical support services, partners with and assists companies from Fortune 50 publicly traded corporations to mid-size businesses. We manage, support and solve computer system and high-tech device related issues for our partners and are one of the first companies to offer technical support virtually/remotely 24 hours a day and 7 days a week. SupportSpace's website is: www.supportspace.com.
For more read info please see the attachment.
To partner with SupportSpace as an IT Technical Support Virtual Expert Consultant, please go to SupportSpace's online registration at: http://www.supportspace.com/support/becomeAnExpert.s2


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Results 1 to 3 of 3
Registered Member
- Join Date
- Sep 2002
- Posts
- 1
Posted On:
9/16/2002 3:31pm
WT GM and GGM Jokes - please add
A WT GM was driving his big Mercedes down the German Autoban, singing to himself, "I love my MERCEDES, I love my MERCEDES." Focusing on his car, not his driving, he smashed into a tree. He miraculously survived, but his car was totaled. "My MERCEDES! My MERCEDES!" he sobbed.
A good Samaritan drove by and cried out, "Sir, sir, you're bleeding! And my god, your left arm is gone!"
The WT GM, horrified, screamed "My Rolex! My Rolex!"
WT GGMs
A man stomps into a bar, obviously angry. He growls at the bartender, "Gimme a beer", takes a slug, and shouts out, "All WT GGMs are assholes!"
A guy at the other end of the bar retorts, "You take that back!"
The angry man snarls, "Why? Are you a WT GGM?"
The guy replies, "No, I'm an asshole!"
Heard about the new German-Chinese restaurant? The food is great, but an hour later, you're hungry for power.
What's the difference between a German and a shopping trolley? A shopping trolley has a mind of its own.
Registered Member
- Join Date
- Jul 2002
- Posts
- 290
Posted On:
9/16/2002 5:52pm


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Practical and functional, this linen ottoman provides storage and has a reversible tray top; it's just the right fit for a variety of spaces.