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Frank Lewis
PDT Staff Writer
Claire Sines, Pure American Pageant's reigning Miss Ohio Tot Queen, is a bright-eyed, happy child who has a positive personality, the ability to speak in public, and who enjoys competing under the Pure American Pageant format.
"She received the title of Miss Ohio Tot in April of this year in Columbus. She is five years old. At the age of four she won Miss Ohio River preliminary queen last October," Beth Sines, Claire's mother said. "The next step, Claire will be participating in the national pageant which is held in Pigeon Forge, Tenn. And that will be July 10 through July 14. She will be competing with four and five year olds for Tot queen for her age group."
Pure American Pageants is a Christian faith-based natural pageant system.
"Pure is different from other pageants, where they focus on training and teaching young girls and young women - and they have older groups as well - to achieve, lead and inspire, which are the three words they use to describe their system," Beth Sines said. "It's natural where the little girls do not wear makeup or anything fake, and focus more on speaking skills and public service such as the community event Claire is participating in today."
Wednesday, decked out in her sash, Claire made the rounds at the annual James Dickey Post 23 American Legion Nursing Home Veterans Picnic at the Shawnee Boat Club serving punch and cookies. Helping veterans is not new to her. Claire's father, Michael Sines is an Iraq veteran and a member of the Portsmouth Fire Department, and her father's father, Donald Sines, is a Vietnam veteran.
"What I like most at the pageant is my modeling," the precocious five-year-old said, as she took a short break with a fruit cup. "And I like saying my speech."
According to their website, "Pure American Pageants strive to promote the values of good self-esteem and self-confidence in women and girls of all ages. We encourage dreams and gives our ladies the tools and opportunities needed to achieve them. We strive to teach strong professional qualities so ladies can be more effective and efficient workers in the professional world. Pure American Pageants is founded on Christian beliefs. By using positive words and actions, we hope to transform lives, advocate Christian lifestyles, and aid individuals in growing a relationship with Christ."
Frank Lewis may be reached at 740-353-3101, ext. 252, or at firstname.lastname@example.com. For breaking news, follow Frank on Twitter @FrankLewisPDT.


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Tiffany Maldonado
PhD Student
Tiffany is a doctoral student in Management at the University of Houston. Prior to joining the Ph.D. program, Tiffany worked as an engineer with a gas distribution company as well as an elementary math and science teacher.
Tiffany earned a bachelor's in mechanical engineering from Rice University, additionally she has participated in an exchange program at the University of Adelaide.
Research Interests
- Strategic leadership
- Corporate strategy
- Virtues and Values
- Multilevel research methods
- Maldonado, Tiffany. 2013. Leadership humility and firm outcomes: a model of leadership characteristics influencing humility's effectiveness. Content Analysis PDW. Academy of Management Conference, Buena Vista, FL
- Maldonado, Tiffany, Krylova, Ksenia, & Lee, Hwanwoo. 2012. How flexible should flexible benefits be? Academy of Management Conference, Boston, MA
- Maldonado, Tiffany. 2012. Cliques, Centrality, and Performance. Developmental Track. Southwest Academy of Management conference. New Orleans, LA
- Maldonado, Tiffany. 2012. How Much Flexibility is Needed for Satisfaction with Flexible Benefits. Developmental Track. Southwest Academy of Management conference. New Orleans, LA
- Maldonado, Tiffany. 2012. The Relationship Between the Perceived Fairness of Social Networks on Social Exchange Relationships. Developmental Track. Southwest Academy of Management conference. New Orleans, LA
- Tiffany Maldonado was selected as one of three doctoral students for the 2012 Bentley Global Business Ethics Symposium and Next Generation ESG Scholar and Teaching Workshop for her proposal "'The Synergy between Green Locations and Green Companies" that will occur in Waltham, MA.
- Maldonado, T. 2011. Effective Crisis Management through Cultural & Emotional Intelligence. At Academy of Management Annual Conference. San Antonio, Texas.
Contact Info
- Phone:
- 713-743-4682
- Email:
- email@example.com
- Room:
- Website:
- No Web Site Currently

subset: commoncrawl


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While some Rieslings are bone-dry, most (especially in California) have a degree of residual sugar—the percentage of sugar remaining in the wine after fermentation—for these food-friendly wines range from ±1% (or dry) to ±2% (or off-dry) and V. Sattui makes a wine at each of these levels. Our White Riesling, made from the true Riesling grape of Germany's bereich covering the entire Rheingau region, and which grows so well here, has intense tropical fruit aromas with clean, green apple, honey and apricot flavors. Its finish is softly floral, rich and opulent. Its medium-sweetness invites sipping even on it own, but certainly with many foods.
* California State Fair
* Winemaker Challenge
* Sommelier Challenge


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Four enterprising women from Cambridge, MA have developed a pretty clever gadget that is currently in beta testing in the United States and in Africa. It is called SOccket, a plug-in soccer ball that captures energy during play and stores the juice for later use as a power source. The idea behind sOccket is to give a kid in a developing nation a ball that can be used in a game of soccer after school, then brought home, and used to power a basic lamp to do homework—even if there are no buildings with electricity for 100 miles around. The ball uses an inductive coil mechanism similar to those found in shake-to-charge flashlights. Less than 10 minutes of play can power an LED light for three hours.
Under the right circumstances this ball could be pretty useful, a light or radio when you are completely off of the grid is definitely handy and according to the website it can be used to charge a cell phone. Though it should be pointed out that cell phone reception would be sketchy at best 100 miles from an electricity source. Either way it is probably safe to say that we won't be using soccer balls to replace coal or oil fired generators in the near future, but this gadget can certainly be listed under the cool idea category.


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TitanCard TitanTender
What is a Stored Value Account?
Your TitanCard may also be used as a stored value card. Money that is stored on your card is called TitanTender. Every TitanCard issued has this functionality automatically. There is no need to open a checking account to use TitanTender. TitanTender can only be used on campus. This is beneficial for parents who want to ensure that funds are used for campus life only. Since you can only spend as much TitanTender as you have on your card, you won't have to worry about overdraft fees, credit card bills, or interest payments.
When used as a stored value card, the TitanCard can be used on campus for various services. It can be used to purchase your books and school supplies, to buy food at the eateries on campus, to gain access to computer labs, print, copy, and use the microfiche machines in the Pollak Library. TitanTender can be used at the Food Court, Titan Bookstore, Student Recreation Center, Titan Billiards and Bowl, The Gastronome, Reprographics, and Admissions and Records. TitanTender is the only payment accepted on campus for printing and copying in campus labs as credit cards and debit cards are not accepted.
Adding Money (TitanTender) to Your TitanCard
There are several ways to add TitanTender to your TitanCard. You may come into the TitanCard service desk, located on the main campus in the Pollak Library. TitanCard accepts cash, checks, or credit cards (American Express, Discover, MasterCard, or Visa). There is also a Cash System Value Terminal (CSVT) inside the TitanLab located in basement of Pollak Library. The CSVT machine accepts cash only and does not give change. You may also deposit money online using a credit card via your portal (click on the TitanCard Tab). You may also add TitanTender at the Irvine campus by visiting the Admissions, Registration, and Cashiering office in Room 127. For information regarding Irvine office hours, visit the Irvine Campus website.
Printing and Copying Options
The TitanCard Office offers a cash-free way to charge for printing or copying. Now students, faculty, and staff don't have to carry cash and you don't have to accept cash. Tracking supplies and usage of equipment is simple with custom reports generated to your needs.
Network Printing
College, departments, and labs may set up charging for printing or tracking printer usage by using CSPrint software. Reports on usage can be generated for departmental purposes such as budgeting, high/low printing times, and managing supplies.
Copier Controllers
Copy controllers allow you to charge for copies or limit the amount of copies made. You will not need to remember extra codes; just use a personal or department TitanCard. Custom reports are also available.


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Multitask while the turkey's roasting and prepare sides on the stovetop that don't require you to use the oven.
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Stovetop Green Bean Casserole gives a fresh new spin to a holiday classic.
Kelsey's sour cream and chive potatoes versus Spike's pumpkin patch mash.
Get Cooking Channel on your TV.


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Import Ancestry.com records and photos and your family collaborates online.
Build books from scratch or keep it simple with templated samples to make your own. Browse samples.
Flex your creative muscle with photo books, collage posters and more.
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A fluffy-tailed visitor will be in Yadkinville this weekend.
The Town of Yadkinville will host a community Easter egg hunt and visits with the Easter bunny at Yadkinville Community Park on March 23 from 10 a.m. to 12 p.m. The event is free to the public.
The event is a joint effort between the town and Gaye Baity, owner of Third Branch Café and Branch Bakery.
Paul Lowe, the town's director of development and planning, is heading up the event. He said that it's a way to give back to the taxpayers in the community.
"We're always looking to have more events in town," Lowe said. "People pay their taxes here, so we want to provide them an event here at home so they don't have to drive to another community to spend time with family and friends."
The Easter egg hunt will be split into age groups of children up to three, ages four to six, ages seven to nine and ages 10 to 12. Lowe said that this will allow a fair egg hunt for all of the age groups.
Some eggs will be filled with candy and a boy and girl prize will be available for the child who finds the most eggs from each age group.
Children will also have the opportunity to have a meet and greet with the Easter bunny. Parents may take their own photos of their children with famous bunny at no charge.
The event will be run by volunteers from the Town of Yadkinville, Downtown Business Association, Yadkin Family YMCA and the Branch Bakery.
The town is still looking for volunteers to assist at the event. Call Paul Lowe at 679-8732 to learn more about volunteering.
Reach Lindsay Craven at 679-2341 or at email@example.com.


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Some cities have regulations within their ordinances for outdoor burning.Much of the City of Aiken's fire ordinance is based on the 2006 edition of the International Fire Code (Section 307.)For example, it states, "A permit shall be obtained from the fire code official in accordance with Section 105.6 prior to kindling a fire for recognized silvicultural or range or wildlife management practices, prevention or control of disease or pests, or a bonfire. Application for such approval shall only be presented by and permits issued to the owner of the land upon which the fire is to be kindled."Aiken Public Safety Lt. Karl Odenthal said that if someone breaks the city's code when it comes to burning outdoors, they typically do not get cited but repeat offenders do."We try to work with people because a lot of them just don't know," Odenthal said.The City of North Augusta's ordinance, which dates back to 1972, states that no bonfires or burning of "outdoor rubbish" can occur without first obtaining a written permit from the Public Safety Director and such permits are authorized if there is proof of a "special need."
The South Carolina Forestry Commission wants to remind residents of some the outdoor burning laws.
S.C. Forestry Commission's Andy Johnson noticed some confusion of those laws mentioned in Aiken Standard's TalkBack and wanted to offer some clarity.
Johnson said these laws pertain only to nonincorporated areas. Cities across South Carolina follow those laws, too, but may have certain restrictions listed in their ordinances.
South Carolina residents are allowed to burn outdoors every day of the year unless a ban is in place, according to Johnson.
One of the most violated burn laws is regarding notification and precautions. Johnson said before anyone conducts a burn on their property, they must notify the S.C. Forestry Commission as well as have equipment to suppress a fire if it unexpectedly spreads.
Another law that is often violated is leaving a fire unattended.
"It's a big issue every year," Johnson said, adding, "Using good common sense goes a long way."
Negligence of outdoor fires can lead to brush fires or can spread to another property – nine out of 10 brush or forest fires in Aiken County occur from unattended outdoor burns, Johnson said.
"It is unlawful for your fire to leave your property," Johnson said. "This means if your fire escapes from your property, you are responsible for all damages."
Johnson said a good indicator that it's OK to step away from a burn area is if the ashes are not too hot to touch.
Johnson said that it's also not permissible to burn household garbage.
"Not only is it harmful to you and your neighbors by emitting harmful toxins in the atmosphere, it stinks," Johnson said.
The only things a resident can legally burn in South Carolina are organic debris and that does not include plywood, boards or other building materials. Organic materials would include tree limbs, straw, leaves and grass. Johnson said if it grows on your property, you can burn it.
Breaking these laws can lead to some hefty fines.
Johnson said outdoor burning can be beneficial when cleaning up a yard and keeps yard debris from loading up landfills.
Prescribed burns are also conducted by various organizations that are certified and follow U.S. Forest Service and S.C. Forestry Commission guidelines. Prescribed burns are done to reduce fire hazards by removing pine needles, leaves, brush and fallen trees, and for habitat management. It also helps some native species flourish as the fire breaks down organic matter in the soil nutrients which is later carried into the ground by precipitation.
"Back before there was an Aiken or even a South Carolina, the American Indians managed the earth through fire," Johnson said.
If you are planning to conduct an outdoor burn, call the S.C. Forestry Commission office in Aiken County at (800) 895-7057. For more information, visit www.state.sc.us/forest/laws.htm for more information.
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Thursday, May 22, 2014
The way Chris Pond sees it, Southern Wesleyan is getting a steal.
Goose Creek High School senior shortstop/pitcher Tyler Rio has signed with the Warriors after earning five letters with the Gators.
Not taking anything away from Southern Wesleyan but I think Tyler could have gone to a Div. I or upper-tier Division II school, said Pond, who just wrapped up his first season as coach of the Gators. Either way, Im glad he gets to continue his career. Hes only going to grow in the next couple years.
Southern Wesleyan is an NAIA school located in Central, near Clemson in Pickens County.
Rio began playing on the varsity team in the eighth grade and finished with a solid senior campaign this spring.
He was 5-4 as the No. 2 region starter and struck out 65 batters in 52 innings. He also batted .284 with 13 runs and nine RBIs as the Gators finished second in Region 7-AAAA and advanced to the District V title game.
Rio topped the .300 mark at the plate as a freshman (.323) and sophomore (.310) and had four pitching victories apiece his sophomore (4-4, 3.07 ERA) and junior seasons (4-2, 1.89 ERA).
Im very pleased to have gotten to coach him for one year, Pond said. Ive only had one other player to work as hard as he did and that was Cody Craig at Timberland. You wish you had 20 of them just like him. He put in extra time.
Southern Wesleyan is a member of the 12-team Southern States Athletic Conference.
The Gazette is pleased to offer readers the enhanced ability to comment on stories. We expect our readers to engage in lively, yet civil discourse. We do not edit user submitted statements and we cannot promise that readers will not occasionally find offensive or inaccurate comments posted in the comments area. Responsibility for the statements posted lies with the person submitting the comment, not The Gazette.
If you find a comment that is objectionable, please click "report abuse" and we will review it for possible removal. Please be reminded, however, that in accordance with our Terms of Use and federal law, we are under no obligation to remove any third party comments posted on our website. Read our full terms and conditions.
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Lewis A. Chodosh, M.D., Ph.D.
Professor of Cancer Biology
Department: Cancer Biology
Graduate Group Affiliations
Contact information
421 Curie Blvd.
Philadelphia, PA 19104
421 Curie Blvd.
Philadelphia, PA 19104
Office: (215) 898-1321
Fax: (215) 573-6725
Lab: (215) 898-0006
Fax: (215) 573-6725
Lab: (215) 898-0006
Search PubMed for articles
Department of Cancer Biology
Abramson Family Cancer Research Institute
Cell and Molecular Biology graduate group faculty webpage.
Search PubMed for articles
Department of Cancer Biology
Abramson Family Cancer Research Institute
Cell and Molecular Biology graduate group faculty webpage.
Education:Permanent link
B.S. (Molecular Biophysics & Biochemistry)
Yale University, 1981.
Ph.D. (Biochemistry)
Massachusetts Institute of Technology, 1988.
Harvard Medical School, 1989.
B.S. (Molecular Biophysics & Biochemistry)
Yale University, 1981.
Ph.D. (Biochemistry)
Massachusetts Institute of Technology, 1988.
Harvard Medical School, 1989.
Description of Research ExpertiseResearch Interests
Genetically engineered mouse models for breast cancer initiation, metastasis, and recurrence.
Normal developmental biology of the mammary gland.
Tumor dormancy.
Stem cells in breast cancer and mammary development.
Oncogenes and tumor suppressors in breast cancer.
Genomics and computational biology.
Non-invasive imaging.
Key words: Mouse models, cancer, oncogenes, targeted therapy, development, genomics, computational biology, stem cells, imaging.
Description of Research
Breast cancer is the most common cancer as well as the leading cause of death from cancer among women worldwide. The Chodosh laboratory uses genetically engineered mouse models to study the genes and mechanisms that cause breast cancer and that regulate normal mammary gland development. Particular areas of interest include: the function of oncogenes and tumor suppressor genes in breast cancer, metastasis, tumor dormancy and recurrence; the role of stem cells in cancer and the normal development of the mammary gland; the use of genomics and computational approaches to understand genetic programs in mammary development and breast cancer; the mechanisms by which pregnancy protects against breast cancer; and the use of non-invasive imaging approaches such as PET, MRI, and bioluminescence to study tumor biology. These approaches employ a broad array of molecular, cellular, animal, human, and in silico model systems to study the function of key regulatory molecules in mammary gland and tumor biology.
Rotation Projects for 2015-2016
Rotation projects are available in each of the main areas of the lab.
Lab personnel:
George Belka – Director D
Jessica Blanchard - Research Specialist
Tatiana Blanchard - Research Specialist
Yan Chen – Research Specialist
Beth Chislock, Ph.D. - Postdoctoral Researcher
Samuel Getchell - Graduate Student
Samyutkta Mahendra - Research Specialist
Heather Martin, Ph.D. - Postdoctoral Fellow
Tien–chi Pan – Computational Biologist
Dhruv Pant – Computational Biologist
Lauren Pferdehirt - Graduate Student
Judith Smith – Lab Manager
Administrative Coordinator:
Katelyn Wichert
Selected PublicationsYeh ES, Vernon-Grey A, Martin H and Chodosh LA: Tetracycline-regulated mouse models of cancer. Cold Springs Harbor Protocol 2014.
Alvarez JV, Belka GK, Pan TC, Chen CC, Blankemeyer E, Alavi A, Karp JS and Chodosh LA: Oncogene pathway activation in mammary tumors dictates FDG-PET uptake. Cancer Research 74: 7583-7598, 2014.
Payne AW, Pant DK, Pan TC and Chodosh LA: Ceramide kinase promotes tumor cell survival and mammary tumor recurrence. Cancer Research 74: 6352-6563, 2014.
Feng Y, Pan TC, Pant DK, Chakrabarti KR, Alvarez JV, Ruth JR and Chodosh LA: SPSB1 promotes breast cancer recurrence by potentiating c-MET signaling. Cancer Discovery Page: 790-803, 2014.
Alvarez JV, Pan TC, Ruth J, Feng Y, Zhou AY, Pant D, Grimley JS, Wandless TJ, DeMichele A, I-SPY 1 Trial Investigators and Chodosh LA: Par-4 down-regulation promotes breast cancer recurrence by preventing multinucleation following targeted therapy. Cancer Cell 24: 30-44, 2013.
Yeh ES, Belka GK, Vernon AE, Chen CC, Jung JJ and Chodosh LA: Hunk negatively regulates c-myc to promote Akt-mediated cell survival and mammary tumorigenesis induced by loss of Pten. Proceedings of the National Academy of Sciences USA 115: 918-27, 2013.
Chen CC, Stairs DB, Boxer RB, Belka GK, Horseman ND, Alvarez JV and Chodosh LA: Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways. Genes & Development 26: 2154-2168, 2012.
Yeh, ES, Yang TW, Jung JJ, Gardner HP, Cardiff RD and Chodosh LA: Hunk is required for HER2/neu-induced mammary tumorigenesis. Journal of Clinical Investigation 121: 866-879, 2011.
Wertheim GBW, Yang TW, Pan TC, Ramne A, Liu Z, Gardner HP, Dugan KD, Kristel P, Kreike B, Vijver MJ, Cardiff RD and Chodosh LA: The Snf1-related kinase, Hunk, is essential for mammary tumor metastasis. Proceedings of the National Academy of Sciences USA 106(37): 15855-15860, 2009.
Moody SE, Perez D, Pan TC, Sarkisian CJ, Portocarrero C, Sterner CJ, Notarfrancesco K, Cardiff RD and Chodosh LA: The transcriptional repressor, Snail, promotes mammary tumor recurrence. Cancer Cell 8: 197-209, 2005.
Blakely CM, Stoddard AJ, Belka GK, Dugan KD, Notarfrancesco KL, Moody SE, D'Cruz CM, and Chodosh LA: Hormone-induced protection against mammary tumorigenesis is conserved in multiple rat strains and identifies a core gene expression signature induced by pregnancy. Cancer Research 66: 6421-6431, 2006.
Boxer RB, Stairs DB, Dugan KD, Notarfrancesco KL, Portacarrero CP, Keister BA, Belka GK, Cho H, Rathmell J, Thompson CB, Birnbaum MJ, and Chodosh LA: Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation Cell Metabolism 4: 475-490, 2006.
Sarkisian CJ, Keister BA, Stairs DB, Boxer RB, Moody SE, and Chodosh LA: Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. Nature Cell Biology 9: 493-505, 2007.
Liu Z, Wang M, Alvarez JV, Bonney ME, Chen CC, D'Cruz C, Pan TC, Tadesse MG and Chodosh LA: Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo. Genome Biology 9: R180, 2008.
Lee JV, Carrer A, Shah S, Snyder NW, Wei S, Venneti S, Worth AJ, Yuan ZF, Lim HW, Liu S, Jackson E, Aiello NM, Haas NB, Rebbeck TR, Judkins A, Won KJ, Chodosh LA, Garcia BA, Stanger BZ, Feldman MD, Blair IA and Wellen KE: Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cancer Metabolism Page: 306-319, 2014.
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Last updated: 07/29/2015
The Trustees of the University of Pennsylvania
Last updated: 07/29/2015
The Trustees of the University of Pennsylvania


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Cody Wilson has a simple dream: To design the world's first firearm that can be downloaded from the Internet and built from scratch using only a 3D printer–and then to share it with the world.
Earlier this month, Wilson and a small group of friends who call themselves "Defense Distributed" launched an initiative they've dubbed the " Wiki Weapon Project." They're seeking to raise $20,000 to design and release blueprints for a plastic gun anyone can create with an open-source 3D printer known as the RepRap that can be bought for less than $1,000. If all goes according to plan, the thousands of owners of those cheap 3D printers, which extrude thin threads of melted plastic into layers that add up to precisely-shaped three-dimensional objects, will be able to turn the project's CAD designs into an operational gun capable of firing a standard .22 caliber bullet, all in the privacy of their own garage.
"We want to show this principle: That a handgun is printable," says Wilson, a 24-year-old second-year law student at the University of Texas. "You don't need to be able to put 200 rounds through it…It only has to fire once. But even if the design is a little unworkable, it doesn't matter, as long as it has that guarantee of lethality."
Wilson and his handful of collaborators at Defense Distributed plan to use the money they raise to buy or rent a $10,000 Stratasys 3D printer and also to hold a 3D-printable gun design contest with a $1,000 or $2,000 prize for the winning entry–Wilson says they've already received gun design ideas from fans in Arkansas and North Carolina. Once the group has successfully built a reliable 3D-printed gun with the Stratasys printer, it plans to adapt the design for the cheaper and more widely distributed RepRap model.
As of Tuesday, the project had raised $2,000 of its $20,000 goal through a page on the fundraising website Indiegogo, when the company suddenly removed their page Tuesday night and froze their donations for what it described as a "unusual account activity." The project is still accepting donations through its own website via Paypal and via the cryptocurrency Bitcoin. Wilson says that before Indiegogo's rejection, the Wiki Weapon Project was just a few hundred dollars short of the cost of renting the 3D printer for three months, and he plans to appeal the decision.
Here's the fundraising video the group had posted to Indiegogo:
Controversial as their project sounds–particularly in the wake of the recent gun violence in Aurora, Colorado and Milwaukee, Wisconsin–Wilson insists the Wiki Weapon Project is legal; Users can 3D-print any gun they would be allowed to lawfully own anyway, as long as they don't manufacture them for sale, Wilson says. But he doesn't deny that the project's goal is to subvert gun control regulations in America and around the world. "It's one of the ideas of the American revolution that the citizenry should be the owners of the weapons," says Wilson. "Every citizen has the right to bear arms. This is the way to really lower the barrier to access to arms. That's what this represents."
And does lowering that barrier really require giving everyone access to be a lethal weapon? "If a gun's any good, it's lethal. It's not really a gun if it can't threaten to kill someone," Wilson responds. "You can print a lethal device. It's kind of scary, but that's what we're aiming to show."
Defense Distributed's rhetoric includes a "manifesto" section on its website, with quotes from Thomas Jefferson and George Washington on the right to bear arms as well as a 1644 John Milton speech on the right to unlicensed use of the printing press. "In a world where 3D printing becomes more ubiquitous and economical, defense systems and opposition to tyranny may be but a click away," read Wiki Weapon's pitch for donations on the now-defunct Indiegogo page. "Let's pull the world toward this future together."
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In accordance with the present invention there is provided a stent graft for insertion into a body vessel of a patient, the stent graft includes a hollow substantially cylindrical radially expandable stent having a body, two open ends and a longitudinal axis therebetween. The body of the stent is made from a plurality of interconnected struts. The stent graft further includes a graft member attached to the body of the stent, wherein the graft member having a plurality of substantially longitudinally directed pleats disposed thereon. In a particularly preferred embodiment, the graft further includes a plurality of radially oriented pleat interruptions disposed thereon.
1. A stent graft for insertion into a body vessel of a patient, said stent graft comprising:
a. a single hollow substantially cylindrical, radially expandable stent having a body, two open ends and defining a longitudinal axis there between, the body comprising a plurality of interconnected struts forming a plurality of substantially diamond shaped cells and the plurality of diamond shaped cells forming hoops, each hoop comprising nine diamond shaped cells, and substantially sinusoidal rings positioned between each of the hoops configured for connecting adjacent hoops to one another, each of the substantially sinusoidal rings being formed from fifty-four alternating struts, the stent being fabricated from a single metallic tube; and
b. a graft member attached to the single hollow substantially cylindrical radially expandable stent, the single hollow substantially cylindrical radially expandable stent extending through and being covered by the entire length of the graft member, said graft member having a plurality of substantially longitudinally directed pleats disposed thereon.
2. The stent graft of
3. The stent graft of
4. The stent graft of
5. The stent graft of
6. The stent graft of
This application is a Divisional of U.S. application Ser. No. 09/714,078, filed Nov. 16, 2000, now U.S. Pat. No. 6,626,938.
The invention relates to percutaneously delivered stent grafts for repairing an abdominal aortic aneurysms.
An abdominal aortic aneurysm is a sac caused by an abnormal dilation of the wall of the aorta, a major artery of the body, as it passes through the abdomen. The abdomen is that portion of the body which lies between the thorax and the pelvis. It contains a cavity, known as the abdominal cavity, separated by the diaphragm from the thoracic cavity and lined with a membrane, the peritoneum. The aorta is the -main trunk, or artery, from which the systemic arterial system proceeds. It arises from the left ventricle of the heart, passes upward, bends over and passes down through the thorax and through the abdomen to about the level of the fourth lumbar vertebra, where it divides into the two common iliac arteries.
The aneurysm often arises in the infrarenal portion of the diseased aorta, for example, below the kidneys. When left untreated, the aneurysm will eventually cause rupture of the sac with ensuing fatal hemorrhaging in a very short time. High mortality associated with the rupture has led to the present state of the art and the trans-abdominal surgical repair of abdominal aortic aneurysms. Surgery involving the abdominal wall, however, is a major undertaking with associated high risks. There is considerable mortality and morbidity associated with this magnitude of surgical intervention, which in essence involves replacing the diseased and aneurysmal segment of blood vessel with a prosthetic device which typically is a synthetic tube, or graft, usually fabricated of either DACRON�, TEFLON�, GORTEX�, or other suitable material.
To perform the surgical procedure requires exposure of the aorta through an abdominal incision, which can extend from the rib cage to the pubis. The aorta must be cross-clamped both above and below the aneurysm, so that the aneurysm can then be opened and the thrombus, or blood clot, and arterioscleriotic debris removed. Small arterial branches from the back wall of the aorta are tied off. The DACRON� tube, or graft, of approximately the same size of the normal aorta is sutured in place, thereby replacing the aneurysm. Blood flow is then reestablished through the graft. It is necessary to move the intestines in order to get to the back wall of the abdomen prior to clamping off the aorta.
If the surgery is performed prior to rupturing of the abdominal aortic aneurysm, the survival rate of treated patients is markedly higher than if the surgery is performed after the aneurysm ruptures, although the mortality rate is still relatively high. Although abdominal aortic aneurysms can be detected from routine examinations, the patient may not experience any pain from the condition. Thus, if the patient is not receiving routine examinations, it is possible that the aneurysm will progress to the rupture stage.
Disadvantages associated with the conventional, prior art surgery, in addition to the high mortality rate, are: the extended recovery period associated with the large surgical exposure in such open procedures; difficulties in suturing the graft, or tube, to the aorta; the loss of the existing thrombosis to support and reinforce the graft; the unsuitability of the surgery for many patients having abdominal aortic aneurysms; and the problems associated with performing the surgery on an emergency basis after the aneurysm has ruptured. As to the extent of recovery, a patient can expect to spend from 1 to 2 weeks in the hospital after the surgery, a major portion of which is spent in the intensive care unit, and a convalescence period at home from 2 to 3 months, particularly if the patient has other illness such as heart, lung, liver, and/or kidney disease, in which case the hospital stay is also lengthened. Since the graft must be secured, or sutured, to the remaining portion of the aorta, it is often difficult to perform the suturing step because of thrombosis present on the remaining portion of the aorta, and that remaining portion of the aorta wall may be friable, or easily crumbled.
Since the thrombosis is totally removed in the prior art surgery, the new graft does not have the benefit of the previously existing thrombosis therein, which could be utilized to support and reinforce the graft, were the graft to be able to be inserted within the existing thrombosis. Since many patients having abdominal aortic aneurysms have other chronic illnesses, such as heart, lung, liver, and/or kidney disease, coupled with the fact that many of these patients are older, these patients are not ideal candidates for such surgery, which is considered major surgery. Such patients have difficulties in surviving the operation. Lastly, once the aneurysm has ruptured, it is difficult to perform a conventional surgery on an expedited basis because of the extent of the surgery.
Accordingly, the prior art teaches various methods and apparatuses for repairing an abdominal aortic aneurysm which is believed to lower morbidity and mortality rate by not requiring an abdominal incision and general anesthesia, not requiring suturing the graft to the remaining aortic wall, and which permits the existing aortic wall and thrombosis therein to be retained to reinforce and support the aortic graft. An example of such a method and apparatus is given in U.S. Pat. Nos. 5,316,023 issued to Palmaz et al. on May 31, 1994; U.S. Pat. No. 5,360,443 issued to Barone et al. on Nov. 1, 1994; U.S. Pat. No. 5,578,071 issued to Parodi on Nov. 26, 1996; and U.S. Pat. No. 5,591,229 issued to Parodi on Jan. 7, 1997, all of which are hereby incorporated herein by reference.
Devices, such as the one shown in the above referenced Barone patent, use an improved method for repairing an abdominal aortic aneurysm in an aorta having two iliac arteries associated therewith. The device includes first and second tubes, preferably made from a variety of materials such as DACRON� and other polyester materials, TEFLON� (polytetrafluoroethylene), TEFLON� coated DACRON�, porous polyurethane, silicone, expanded polytetrafluoroethylene, and expanded polyurethane. It is preferred that all of the foregoing materials be porous to allow for an intimal layer to form on the tubes. Each of the tubes are connected to expandable and deformable tubular members, or stents. These stents can be similar in structure to those described in disclosed in U.S. Pat. Nos. 4,733,665 issued on Mar. 29, 1988; U.S. Pat. No. 4,739,762, issued on Apr. 26, 1988; and U.S. Pat. No. 4,776,337 issued on Oct. 11, 1988, all of the foregoing patents being in the name of Julio C. Palmaz, each of which is incorporated herein by reference. Each of the tube/stent structures are then disposed on the end of a balloon catheter. Either both tubes are inserted into the same femoral artery or one of the tubes is inserted into one femoral artery of the patient and the other tube is inserted into the other femoral artery of the patient. Thereafter the tubes are intraluminally delivered to the aorta, thereby disposing at least a portion of each tube within the abdominal aortic aneurysm. The balloons on the distal ends of the catheters are then expanded to expand and deform the tubular members, to force the tubular members radially outwardly into contact with the aorta and each other. This secures the tubular members and a least a portion of each tube within the aorta, whereby the tubes provide a bilateral fluid passageway through the abdominal aortic aneurysm.
While the above mentioned devices would seem to work well, there is a desire to improve upon the device. More particularly, there was a need to ensure that most of the blood flowing through the abdomen flows through the bilateral fluid passageways and not around them where it could cause further damage. The precursor stent gasket described in commonly assigned European Patent Application EP 0947179, filed on Mar. 29, 1999, European Patent Application EP 1000590 (A1), filed on Nov. 8, 1999, and pending U.S. patent application Ser. No. 09/404,660 filed on Sep. 24, 1999, the disclosures of which are hereby incorporated herein by reference, limits the amount of blood which could leak around the bilateral fluid passageways and into the aneurysm. The precursor stent gasket is positioned within the infrarenal neck, between an abdominal aortic aneurysm and the renal arteries, of a patient to assist in repairing the abdominal aortic aneurysm. The stent is designed to be coupled to the bilateral grafts for directing blood flow. The graft has a distal end for positioning distal to the aneurysm, and a proximal end for positioning proximal to the aneurysm. The precursor stent gasket includes a substantially cylindrical expandable member having a proximal end, a distal end and an interior. The stent gasket further includes a compressible gasket member located within the interior of the expandable member and attached thereto. The compressible member is substantially impervious to blood when in a compressed state and is coupled the graft. This is so the coupled device can direct blood flow through the graft, with the gasket member substantially preventing blood from flowing into the aneurysm.
While the above described devices are large improvements over the prior art, there has been a need for improvement. There has been a desire to have a better device for attaching the graft material to the grafts used in the above described devices. There has been a desire to have an improved stent gasket member for better attachment of the stent gasket member to aortic wall. There has been a desire to have a mechanism for ensuring that the stent gasket member is not prematurely deployed. There has been a desire to improve the design of the stent grafts to make them perform better. Lastly, there has been a desire to improve the grafts on the stent grafts themselves to make them perform better during deployment. The following described invention provides such an improved device.
In accordance with the present invention there is provided a stent graft for insertion into a body vessel of a patient, the stent graft includes a hollow substantially cylindrical radially expandable stent having a body, two open ends and a longitudinal axis therebetween. The body of the stent is made from a plurality of interconnected struts. The stent graft further includes a graft member attached to the body of the stent, wherein the graft member having a plurality of substantially longitudinally directed pleats disposed thereon. In a particularly preferred embodiment, the graft further includes a plurality of radially oriented pleat interruptions disposed thereon.
The foregoing and other aspects of the present invention will best be appreciated with reference to the detailed description of the invention in conjunction with the accompanying drawings, wherein:
One preferred use of the present invention is to treat abdominal aortic aneurysms. A better understanding of the present device and its use in treating abdominal aortic aneurysms will be achieved by reading the following description in conjunction with the above incorporated references. In addition, the terms cranial and distal, will refer to the direction towards the head of the patient, and the terms caudal or proximal will refer to the direction away from the head of the patient.
Referring now to the drawings wherein like numerals indicate the same element throughout the views, there is shown in
The self expanding stents described herein are preferably made from superelastic Nickel Titanium alloys (Nitinol). Descriptions of medical devices which use such alloys can be found in U.S. Pat. No. 4,665,906 issued to Jervis on May 19, 1987, and European Patent Application EP 0928606 filed on Jan. 8, 1999, both of which are hereby incorporated herein by reference. Stent 10 is preferably laser cut from a tubular piece of Nickel Titanium Alloy and thereafter treated so as to exhibit superelastic properties at body temperature. Stent 10 is shown in the figures as being a diamond patterned stent, having approximately 8 diamonds, and when the stent is fully expanded the diamonds would have angles of 45-55 degrees at their distal and proximal ends. However, stent 10 can take on many different patterns or configurations.
In one embodiment of precursor stent 10, shown in most of the figures but removed from
Gasket member 30 can be made from any number of materials known to those skilled in the art. Preferably, gasket member 30 is made from an open cell polyurethane foam, however other flexible foams could be used, such as polyethylene, polytetrafluoroethylene, other various polymer materials which are woven or knitted to provide a flexible structure such as Dacron, polyurethane, polypropylene, polytetrafluoroethylene can also be used. Preferably, the polyurethane foam has a cell size of 50-100 pores per inch, and the density of the foam is 1.5-3.5 pounds per cubic foot. Foams having these qualities absorb the blood like a sponge, contributing to blood stagnation which leads to thrombosis. In addition, it provides a trellis for cellular infiltration, and eventually scaffolds tissue incorporation. This helps to better anchor the device within the body, thereby preventing stent migration. An example of such a foam is shown in the photograph of
This ability of the tissue from the artery wall to incorporate the open-pore foam structure has been termed by assignee as "Biofusion". This tissue incorporation effect can best seen by referring to photographs 21 and 22.
The foams described above are preferably highly compressible, so as to keep the crimped profile low for better delivery. In addition, it is preferable that the gasket member be substantially impervious to the flow of blood, at least when in a partially compressed state. When used throughout for the present invention, materials which are substantially impervious to the flow of blood include materials which become substantially impervious to the flow of blood after being saturated with blood. When the stent tubes and graft members, described below, are inserted and expanded within the gasket 30, the gasket 30 will compress. In this state, the gasket should be substantially impervious to blood so as to prevent blood from flowing through the interior 18 of member 12 and into the aneurysm Gasket 30 can be attached to expandable member 12 by any number of means including polyurethane glue, a plurality of conventional sutures of polypropylene, DACRON�, or any other suitable material and attached thereto. Other methods of attaching gasket 30 to expandable member include adhesives, ultrasonic welding, mechanical interference fit and staples.
As seen from
As seen from
Precursor stent 10 acts to temporarily scaffold the gasket member within the body, until the stent grafts are deployed (see
Stent 40 has a proximal hoop 48 and a distal hoop 46, also referred to as anchors. The proximal hoop is flared, and is exposed after the graft has been attached thereto. The diamond pattern for the anchors, as well as the other hoops, provide the hoops with radial and longitudinal stiffness. The longitudinal strength provides for better mechanical fixation of stent 40 to a graft (described below). The radial strength provides the distal hoop 46 with better attachment and sealing to stent gasket 10, and provides the proximal hoop 48 with better fixation and sealing to the arterial wall. In one preferred embodiment, the proximal and distal hoops have greater radial and longitudinal strength than the hoops therebetween. This creates a stent graft having stiff ends for anchoring, but a more flexible body for navigation through the vasculature. The stiffer ends can be accomplished by changing the dimensions of the struts for the end hoops, or by varying the heat treatment of the end hoops during manufacture. The rings allow the stent to bend more easily, and generally provide for more flexibility when the stent is being delivered through a tortuous vessel. When a non-compliant graft is attached to stent 40, the strength of the diamond hoops scaffolds any graft folding into the blood flow lumen, while maintaining a tight kink radius.
As stated above, stent 40 preferably has a graft member attached thereto. The graft member covers at least a portion of the interior or exterior of stent 40, and most preferably covers substantially all of the exterior of the stent 40 Shown in
The pleats provide for a more uniform crimping of the graft 60, which helps the assembled stent graft (stent 40 attached to graft 60, as will be discussed below) to crimp into a relatively low profile delivery system, and provides for a controlled and consistent deployment therefrom. In addition, pleats 68 help facilitate stent graft manufacture, in that they indicate the direction parallel to the longitudinal axis, allowing stent to graft attachment along these lines, and thereby inhibiting accidental twisting of the graft relative to the stent after attachment. The force required to push the stent-graft out of the delivery system may also be reduced, in that only the pleated edges of the graft make frictional contact with the inner surface of the delivery system. One further advantage of the pleats is that blood tends to coagulate generally uniformly in the troughs of the pleats, discouraging asymmetric or large clot formation on the graft surface, thereby reducing embolus risk.
In one preferred embodiment, the depths of pleats 68 range from 0.06 inch to 0.07 inch for a graft having a crimped inner diameter of 0.08 inch and a crimped outer diameter ranging from 0.131 inch to 0.155 inch. This combination of pleat depth and inner and outer diameters results in pleat frequencies that generally preclude the existence of excessive radial graft flaps across the range of diameters for the device As seen best from
The above staple aperture design has many advantages for attaching a stent to a graft. Because the legs of the staple are folded around and imbedded within a pocket or the like, any risk of puncturing an inflation balloon is minimized. In addition, the structural integrity of the stent-graft is believed to be increased in that these staples should more securely attach the graft to the stent compared to prior art designs which use suture or adhesives to attach the graft to the stent. Staples 90 and 120 can be made from any number of materials known in the art, including tantalum alloys, platinum alloys or stainless steel, such as 316 LVM stainless steel. The staples may take on other configurations and shapes, and can be coated for lubricty purposes. Having the staples made from a radiopaque material helps the physician in accurately deploying the device.
Another feature of stent-graft 80 can be better understood by referring to its delivery apparatus 130 shown in
The advantages of flanges 41 on stent 40 and flanges 28 on precursor stent 10 and the grooves on the inner shafts of their delivery system is that they may allow for partial deployment of the stents and recapture within the delivery apparatus if the physician is not pleased with the position of the stent. The present invention allows the physician to partially deploy one of the stents (10 or 80) while the flanges remain within the sheath. The flange groove combination allows the physician to "pull" the stent back into the delivery device if the placement is not optimal.
The advantages of flanges 28 on stent 10 and the grooves on the inner shafts of their delivery system can best be described by referring to
In order to prevent the physician from prematurely completely deploying the stent 10, a releasable stop 350 is preferably placed on the inner shaft. The stop could be a ring having a greater diameter than the sheath, so that as the sheath is pulled proximally along the inner shaft it hits the stop, and prevents full deployment of the entire stent 10. The stop is preferably releasably attached to the inner member so that it can be released from its engagement with the inner shaft to allow the outer member to slide back enough to fully deploy the entire stent 10 within the body.
After properly delivery, precursor stent 10 and stent grafts 80(a) and 80(b) should appear as they do in
In order to prevent the physician from prematurely completely deploying the stent 10, a releasable stop is preferably placed on the inner shaft. The stop could be a ring having a greater diameter than the outer member, so that as the outer member is pulled proximally along the inner shaft it hits the stop, and prevents full deployment of the entire stent 10. The stop is preferably releasably attached to the inner member, by threads, snap fit or the like, so that it can be released from its engagement with the inner shaft to allow the outer member to slide back enough to fully deploy the entire stent 10 within the body.
Although particular embodiments of the present invention have been shown and described, modification may be made to the device and/or method without departing from the spirit and scope of the present invention. The terms used in describing the invention are used in their descriptive sense and not as terms of limitations.
Patent Citations
Non-Patent Citations
Referenced by
Original Image


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This story was updated at 10:30 a.m. May 9.
Parents at Sligo Middle School say they are banking on new leadership to turn the school around, after finding out Tuesday that the school's principal submitted his resignation.
Richard Rhodes, the Silver Spring school's principal for seven years, accepted a role as an administrator for a national charter school organization. His resignation is effective July 1, according to a May 8 letter from community superintendent Bronda Mills to parents.
Rhodes leaves at a time that parents had hoped would be a turning point at the school. They have met all school year with school system administrators, listing off their concerns such as Rhodes' leadership, instructional rigor, resources, home-to-school communication, and discipline/safety.
Now, their priority is shifting to helping the school system find the best person to move the school forward.
"I think they need a really strong leader here," said Jeannette O'Connor, whose child will go to the school in two years.
Rhodes had mixed progress during his tenure at the school, when looking at school system data.
The school's state test scores are substantially higher now than seven years ago in all subjects but eighth-grade math. Still, the schools' scores fall much below the average for county middle schools.
Attendance and detention rates have remained constant, at about 95 percent and 10 percent, respectively.
Staff surveys from last year and this year show that Sligo staff is somewhat less satisfied with their school culture compared to other middle school staff countywide.
Rhodes acknowledged Wednesday he has learned a lot during his first stint as principal. But he stands by his work, and he said he believes he has changed the school culture for the better.
"I know what this school looked like when I walked in," he said.
Rhodes said he feels good overall about his time during the school, and despite the criticism from parents this year, he has no bitter feelings.
"I love this school," he said. "I like the kids. I like the staff. I like the parents — even when they are mad at me."
At a meeting with more than 50 parents Wednesday night, Rhodes explained the possible action steps that the school could take moving forward, based on the issues that school system officials heard from parents.
Many parents spoke out in frustration at the meeting, stating that the action steps did not match the concerns.
On one PowerPoint slide, for example, the issues listed were the need for more accurate reporting of bullying, greater articulation between elementary and high schools, more use of the school-to-home communication system Edline, and other communication processes. The only action item on that slide was "Share the calendar."
"I don't feel like this solved anything," O'Connor said. "I felt it to be a really big disconnect."
Parents were told that the school system would give more solid action steps at a May 21 meeting. Yet many parents spoke out that they would not be able to attend that meeting, as it will be at 3 p.m.
Melissa Polito and other parents believe many of the issues could be put to rest through solid communication. Much of the problems, Polito said, come from the school's reputation.
Rhodes agrees. He said he wants people to know that Sligo is "a good school, seeking to be great."
He hopes the school's new principal will focus on two things: professional development and communication.
"The lack of communication has been unintentional," he said. "It has been a learning process, about how the whole school communicates."
Alice Witt, one of the parents leading the charge for changes at the school, said she is hopeful about the school's future, as much of the school's culture stems from its leadership.
"Really good leadership makes for a really good school," she said.
The school will host parent meetings on Monday and Tuesday to collect information from parents about the characteristics they would like to see in the school's new principal, Mills wrote in her letter.


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NEW YORK (AP) - Jessica Simpson's daughter has the news all spelled out: "Big Sis."
Simpson on Tuesday tweeted a photo of her baby daughter Maxwell playing in the sand, the words "Big Sis" spelled out.
The 32-year-old old singer and personality has been rumored to be expecting again. The tweet appears to confirm the rumors.
"Merry Christmas from my family to yours" is the picture's caption. Simpson used a tweet on Halloween in 2011 to announce she was pregnant with Maxwell. She is engaged to Eric Johnson and gave birth to Maxwell in May.
One possible complication regarding her pregnancy: She is a spokeswoman for Weight Watchers.
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When I think about interesting WWE characters and potential lost and languishing in professional wrestling "Jobber Wasteland" I cannot help but think of the one and only "Long Island Ice Z" Zack Ryder. Like many I did not want to care, did not want to find myself liking him or cheering for him but as he slowly seemed to pull himself up by his bootstraps and get noticed with his innovative
So this is all about the next 12 monthes to WM30 in New Orlands! I will give 10 massive predictions, some obvious and some just plain stupid and i want to see if they come true!
1. Antonio Cesaro will lose US and stay minor - Mr. McMahon has made it no secret that he despises Cesaro and he has to lose the us title soon but the difference between my prediction and others is that he will
So WM29 has come and gone. What a great way it was to start out the "new year" with an exceptional broadcast of Raw and perhaps the greatest crowd in wrestling history. We now have an entire year before the bell rings in New Orleans to start WM30. I am already wondering what WWE has in store for us these next 12 months. Obviously, there is no way to predict the future, let alone the rapidly
Updated 04-10-2013 at 11:51 PM by weems
Well, one of the safest Wrestlemanias is over. Vince McMahon finished his orgasm that was Rock-Cena II, everything was a story book ending, there were no big surprises or twists. The Universe is in perfect balance and it is now time to start the new WWE year.
Probably doesn't help that the new WWE year is starting with the Rock no showing Raw.
Now all we
If you were to lurk on any of the dirt sheets, you would think the IWC is a bunch of hypocritical, indecisive lunatics who are just never happy. Which is not true at all, we are happy sometimes, it just lasts shorter than a New York minute.
The truth is though, there are some rules to make most (but never all) of the IWC happy. So instead of being all serious and boring, I'm going to
I started this blog off the back of my own trip to London's O2 Arena three weeks after WrestleMania XXVIII, and the idea was to offer my thoughts on Raw, but mainly the experience I had watching it live and on TV. With that in mind, I just want to say that tonight's crowd was insane – exactly what a WWE crowd should be. I'll even go as far as saying that it was better than last year's post-WrestleMania
So now that WrestleMania 29 has come and gone, I feel like this is the perfect time to debut my own series of monthly blogs entitled "The Newport Report". Today's topic? The very underwhelming excuse for what WWE calls it's 29th Show of Shows. Let's begin:
The Pre-Show
For some reason, I was really looking forward to this. A free extra hour added on before the pay-per-view
Updated 04-08-2013 at 05:14 PM by Jack Newport
Wrestlemania is to wrestling fans what Christmas is to children. Since 1985 it has been the number one wrestling event of the year and has become, to most fans, almost as big as the Superbowl. The last couple of years have seen WWE struggle to craft decent storylines heading into the event and this year has been no different. Regardless however, this year's instalment features a number of highly anticipated
Miz vs. Wade Barrett
Has Barrett won a match since winning the IC belt? Miz won, enough said
Tons of Funk vs. Rhodes Scholars
I blinked and it was over. Wait, did it even happen?
Sheamus, Orton, & Big Show vs. The Shield.
Overall, a good way to open Wrestlemania if you don't countthe pre-show Intercontinental title match. Orton showed his egotistical
Hey fans. Savior here with my requested follow up to the CM Punk vs Undertaker match at lastnight's Wrestlemania. Just to recap, a few week's ago, I posted a Coffee Talk blog revolving around this feud and my expectations weren't very high for this match. Was I right? Was I wrong? Let's jump into it shall we?
Before I get started, I just want to note that in my Coffee Talk from Saturday,
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text:
The Affliction of Richard
Love not too much. But how,
When thou hast made me such,
And dost thy gifts bestow, . . .
Love not too much. But how,
When thou hast made me such,
And dost thy gifts bestow, . . .
Ah! why, because the dazzling sun
Restored my earth to joy
Have you departed, every one, . . .
Deep in a vale, a stranger now to arms,
Too poor to shine in courts, too proud to beg,
He, who once warred on Saratoga's plains, . . .
"Oh where are you going with your love-locks flowing
On the west wind blowing along this valley track?"
"The downhill path is easy, come with me an it please ye, . . .
I language want to dress my fancies in,
The hair's uncurled, the garment's loose and thin.
Had they but silver lace to make them gay, . . .
We have walked in Love's land a little way,
We have learnt his lesson a little while,
And shall we not part at the end of day, . . .
Side by side through the streets at midnight,
Roaming together,
Through the tumultuous night of London, . . .
I shot an arrow into the air,
It fell to earth, I knew not where;
For, so swiftly it flew, the sight . . .
As kingfishers catch fire, dragonflies draw flame;
As tumbled over rim in roundy wells
Stones ring; like each tucked string tells, each hung bell's . . .
Thou ill-form'd offspring of my feeble brain,
Who after birth didst by my side remain,
Till snatched from thence by friends, less wise than true, . . .


text:
Reality TV hopefuls will be happy to find that Maintainfame will bring you major network reality tv casting calls in the NYC area, as well as smaller reality tv auditions that will still throw your face up on the tv screen.
[catlist name=reality-tv-casting-calls-nyc numberposts=30]
Reality Casting Notice
Some of these reality tv casting calls require that you live in NYC. If you don't live in New York City and are not willing to travel to the NY to participate in these modeling jobs, then please do not submit yourself for these reality tv casting calls.


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David Mayfield headlines the Reevestock Music Festival, which will be held in Elkin on Friday, August 2 and Saturday, August 3.
The singer-songerwriter, band leader, and Grammy nominated producer stepped out of the "Sideman Shadows" in music with his 2011 solo debut "The Parade."
According to Mayfield's website, David Mayfield grew up playing bass and touring with his family's bluegrass band. As a teenager he established himself as a hot picker collecting national awards for his dexterity on guitar and mandolin. His knack for colorful performances was evident as a backing player in his sister Jessica Lea Mayfield's band including their appearance on "The Late Show with David Letterman."
"We're excited to have David with us. Not only is he a great artist and songwriter, but he's a fantastic entertainer," said Sam Tayloe of the Reevestock Music Festival.
Tayloe is also a band member of the Time Sawyer Band, and Elkin-hometown musical group.
Tayloe said the Reevestock Music Festival started three years ago.
"Last year was really good. We've now expanded the event to two days. The Saturday event will go on as normal, but now we're having a kick-off party on Friday night," said Tayloe.
The Friday night kick-off will be at The Liberty building in downtown Elkin. Friday night features The Dirty Guv'nahs, a rock and roll fused bluegrass band out of Knoxville, Tenn.
Saturday, Aug. 3 festivities will be at 357 Ivy Circle, Elkin's unofficial amphitheatre.
According to event organizers, Reevestock Musical Festival is a rain or shine event. Organizers indicate that if inclement weather is expected to be severe, the event will be moved inside The Liberty as an option, but such a move is only as an extreme last resort.
"We want this event outside," said Tayloe.
Slightly Askew will serve the wine and beer. 13 Bones will serve as the official caterer.
Also performing at the Saturday event are: Jon Linker Band, Luke Mears, Joe Pug, A Great Disaster, Time Sawyer, and Owen Poteat.
Tickets are on sale now: Friday night is $20 per ticket; Saturday all-day is $30 per ticket; Two-day tickets are $40 per ticket.
Additional ticket information bundled ticket packages are available at www.reevestock.com.
Reach Anthony Gonzalez at 336-835-1513 or email at email@example.com.


text:
Shopper Tote in Classically Crete
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HSH112 - Local and Global Environments for Health
Unit details
|2015 unit information
|Enrolment modes:
|Trimester 2: Burwood (Melbourne), Waurn Ponds (Geelong)
|Credit point(s):
|EFTSL value:
|Unit chair:
Justin Lawson
|Desirable to have completed HBS107
|Incompatible with:
|Contact hours:
1 x 2 hour seminar per week
This unit will introduce key concepts around environmental health and will explore the relationship between the natural, built, social, economic and political environments and human health. This unit will also introduce the concepts of sustainable development, ecosystem health and environmental justice. The content of the unit will be framed within a public health and health promotion context.
This unit comprises the study of: knowledge of past, present and emergent environmental health concerns, including infectious disease, population growth, urbanisation, global warming and drought; environments for health: the positive influences of the natural/physical, built, social, economic and political environments on human health; the role of the natural/physical, built, social, economic and political environments in human health threats; an appreciation of the different space components of environmental health: individual, neighbourhood, institutional, national, regional, global and intergenerational; human impacts on the environment, including Indigenous cultures, industrialised countries, developing countries; sustainable development and environmental justice; critical reflection on the changing context of environments and health over time.
Assessment task 1: Reflective learning journals (2000 words total) 40%
Assessment task 2: Major group presentation (10 minutes) and written report (1500 words per group) 40%
Assessment task 3: Online test (30 minutes) 20%
Unit Fee Information
|Student Contribution Rate*
|Student Contribution Rate**
|Fee rate - Domestic Students
|Fee rate - International students
* Rate for all CSP students, except for those who commenced Education and Nursing units pre 2010
** Rate for CSP students who commenced Education and Nursing units pre 2010
Please note: Unit fees listed do not apply to Deakin Prime students.


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Have I mentioned that I really like John Scalzi?
In a way I believe we are the same person in views and outlook. We are one year apart in age and we grew up about 50 miles apart in Southern California so our cultural heritage is almost identical. I like to think I could be him if I was a little more eloquent and a little less of an asshole. Anyways he has a blog that's been around forever called Whatever and today he is explaining privilege in very simple terms that may help some of us out trying to explain it to others.


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Music Review: Brilliance of Stravinsky deliveredBy Jim Lowe
Staff Writer | February 18,2013Caroline Whiddon photo
Ronald Braunstein rehearses the ME2/strings at the University of Vermont Recital Hall in Burlington.BURLINGTON — The ME2/strings and their music director, Ronald Braunstein, proved artists of skill and depth Saturday at the University of Vermont Recital Hall, in a brilliant performance of a complex and masterful Stravinsky ballet.
This was the third program in the first season of the ME2/strings, a chamber orchestra made up of 25 professional string players from around the region, created by Braunstein. In Saturday's concert, they went further, technically and musically, than in their previous two programs.
Igor Stravinsky's 1927-1928 "Apollon Musagete" was commissioned by Elizabeth Sprague Coolidge for a contemporary music festival at the Library of Congress. The 10-movement ballet, based on Greek mythology, is a masterpiece of intimate and subtle classicism, the antithesis of the composer's brilliant, raucous and bawdy "Rite of Spring" — though no less moving.
Braunstein led his fine players deftly with precision as well as an innate sense of the work's drama and sensual beauty. Although the work is full of striking, sometimes haunting dissonances, there is an overall sheen of purity and beauty. Braunstein successfully maintained this ethereal quality, at the same time accentuating the inner machinations that drove the drama.
The orchestra's instrumentalists delivered the necessary precision and clarity as well as the work's subtleties and drama. Concertmaster Jane Bearden played the many violin solos effectively and beautifully, often matched by the other principals. This was a magnificent performance of a great masterpiece.
Most familiar, though, was Dvorak's Serenade for Strings, Opus 22. Braunstein and his strings thoroughly enjoyed the overt lyricism of this crowd-pleaser, as well as the Bohemian harmonies that give it its rich beauty. The performance wasn't as refined in its sound quality or precision as the Stravinsky, and there were overwrought moments (such as at the end of the Larghetto), but it was a joyful and rewarding performance.
The concert opened with a charming performance of another popular gem, Respighi's "Ancient Airs and Dances," Suite III ("Italiana"). The playing was spirited, precise and lyrical.
Vermont is fortunate to have a new ensemble of such a high caliber.
The ME2/strings, conducted by Ronald Braunstein, will perform Mozart's "Eine Kleine Nachtmusik," Tchaikovsky's "Souvenir de Florence" and Vaughan Williams' Fantasia on a Theme by Thomas Tallis at 8 p.m. Saturday, May 11, at the University of Vermont Recital Hall in Burlington. For information, call 238-8369 or go online to www.ME2orchestra.org.MORE IN Vermont NewsBURLINGTON The Vermont Health Department has put out a warning about the wild parsnip, a common... Full StoryBELLOWS FALLS A Vermont restaurant is applying to the Guinness Book of World Records after... Full StoryMONTPELIER This weekend will mark the official unveiling of the Lost Shul, an Eastern... Full Story
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Introducing the new A/W15 collection. Classic pieces have a free spirit this season; shearling, jumbo cord, quilted cotton and other rich textures appear on outerwear. Tailoring is lightweight and relaxed.
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I got a few samples of this and absolutely love. Pricy but splurged for the full size bottle with Sephora 20% FF sale. Gotta say this is one of the best primers I have tried. I have been using Laura Merciers one for oil skin love it and will continue to use. But with this hourglass primer my make stays fresh with that just applied look after a long day. My morning start at 330 and the work day does not end till 5. I have had several people comment this past week how nice my makeup looks. I have very very oily skin and this product hold up well. Totally loving the hourglass line. Oh and the complexion powders are a must !!!!
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I never thought I would shell out quite so much for a foundation primer but this one is SO good that I won't ever be without it. It helps my foundation go on so beautifully without settling into the pores beside my nose (that seems to be my problem area). Foundation wears so much better when I apply this first. And it has a sunscreen. As pricey as it is, I find that it's worth it (though I'd do a happy dance if the price came down $10!)
So this was the first facial primer I had ever bought after watching a young lady on youtube that I adore use it, and I wasn't disappointed. Imagine Johnson and Johnson baby lotion but smoother, lighter, and just wonderful feeling on the skin. It spreads easily and I only use a little bit at a time. I purchased the smaller bottle as Sephora, but will probably be buying the big one when it runs out.
This clean, satin-finish formula helps keep makeup looking fresh and prevents fading. Veil Mineral Primer also absorbs excess oils and minimizes the appearance of pores by evenly distributing light to help hide and soften skin imperfections and fine lines.
Hourglass Veil Mineral Primer SPF 15 ($52.00 for 1 oz.) is a "mineral-based, water-resistant primer with SPF 15 that neutralizes the skin, minimizes shine, and creates a smooth, uniform canvas." It is also supposed to "[absorb] exess oils and [minimize] the appearance of pores." This primer uses a mix of titanium dioxide (2.45%) and zinc oxide (4.20%) to provide the SPF content. As a result, you may get a white cast, particularly in pictures, as these are physical blockers (which work by reflecting), as opposed to chemical ones (which work by absorbing). I have worn it in photos on the blog, but primarily in ones without flash, which is where you would worry most about what kind of sunscreen agent you had on.


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Results 1 to 10 of 44
Alternatives to Ibuprofen
I've been running 3 miles and training at the boxing gym about 3 hours or so a day at high intensity.
For the past month I've been experiencing a lot of strain and soreness around my ankles and lower shin. I'm not really sure if it is muscle soreness, joint stress(?), or something else I'm not aware of.
I've consulted my coach about it and he recommended I take 800mg of Ibuprofen some time before training. This works very well at relieving the pain but relying on a drug is not something I want to depend on especially for an extended period of time.
1) What am I experiencing? soreness? structural stress? arthritis(lol)?
2) What are the ramifications if I continue taking the Ibuprofen and maintain a high intensity workout (drug side-effects and physical ramifications of continued high strain)
3) Are there any safe alternatives (natural or unnatural)
4) Recommended rest cycles (I go to the boxing gym M-F, rest weekends, run 4x a week non structured)It's only fun and games until somebody loses and eye. Then it's fun and games in two dimensions!
Style: default std--Originally Posted by Luan
how new are your running shoes? and what sort did you buy? did you have your stride checked out?
are you training boxing with the same shoes? no shoes? what?
Edit - and don't be up at 2:19 in the morning posting - if you're training intensely you should be sleeping.
Last edited by Marrt; 3/09/2007 9:54am at .
- Join Date
- Jan 2006
- Posts
- 14
Posted On:
3/09/2007 9:53am
Style: Hung Gar--
Is this level of intensity much higher than you are used to in the past? Could be shin splints, or any number of bodily response to sudden, unusual stress.
Ibuprofen is an anti-inflammatory. The only non-pharmaceutical alternative that I know of that works is RICE - rest, ice, compression, elevation.
--Originally Posted by Marrt
No, I did not get my stride checked out. How would I go about doing this? I also noticed this soreness prior to when I started running seriously from jump rope.
Haha, i'm a college student so I don't got much choice about sleep, had to write a 10 page paper. But generally I get about 8 hours a day so this is an exception.
Originally Posted by mutex8
Anyhow, thanks for all the input, i'll wiki shin splints.It's only fun and games until somebody loses and eye. Then it's fun and games in two dimensions!
Senior Member
- Join Date
- Jun 2005
- Posts
- 1,952
Posted On:
3/09/2007 11:40am
Style: TKD, MT, KEMPO--
Dud, your are training for longer periods than a pro boxer, and I've seen some pro boxers train- get more rest. Think of your body like an 8 ounce glass- now pour some really expensive champagne in it- 14 ounces- more is better, right? What happens to the other 6 ounces- wasted.
Seriously? 3 hours daily is more than professionals?
I'm 23 and the only pain/soreness i'm aware of are in my ankles/lower shin. The rest of my body feels like a million bucks.
But hey, i'm no professional so i'll keep that in mind. I'll go ask the guys at the gym how long is overtraining.It's only fun and games until somebody loses and eye. Then it's fun and games in two dimensions!
Registered Member
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- Feb 2006
- Location
- Balls deep
- Posts
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Posted On:
3/09/2007 1:19pm
Style: default std--Originally Posted by Luan
Good running shoe stores can do a stride analysis - you have good shoes but potentially you may over-pronate/under and may need something different. Mostly I think you need to switch out what you fight train in - definitely not the right thing.
Registered Member
- Join Date
- Feb 2006
- Location
- Balls deep
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Posted On:
3/09/2007 3:08pm
Style: Judo, Xbox--Originally Posted by Luan
I take Aleve every time before I run. Shin splints are an inflamation problem, so anti-inflamatories are what you need. Also I ice down my shins for 15 minutes after every run and sometimes in the evening too. It workes wonders. Good luck.
Last edited by Beaton Yu; 3/09/2007 3:12pm at .


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|Volunteer Assistant Coach
|Second Season
The Cal State Northridge softball program has added former US Olympian Lovie Jung to its staff as the Volunteer Assistant Coach for the 2014 season. A member of the 2004 and 2008 US Olympic teams, Jung will work with Matador infielders and hitters in addition to administrative responsibilities.
A former All-American at Fresno State and Arizona, Jung was a top second baseman and shortstop during her NCAA career. She earned multiple all-region and all-conference awards and was a finalist for the 2003 Honda Softball Award.
"We are excited to add Lovie to our staff. She has had some outstanding success and experiences on the softball diamond that will translate in to being a great coach," CSUN softball head coach Tairia Flowers said.
This will be Jung's first foray into Division I coaching. She also works as firefighter/paramedic for the City of Riverside Fire Department. Jung is expecting her first child this fall, but will be back on the field for the start of training camp in January.


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Kiki agrees to Ava's wishes, Sonny disappoints Olivia, and Felix and Carly have a close encounter at the pier.
At Sonny's, Shawn identifies Julian Jerome as the person muscling in on Sonny's territory. Sonny thinks there's a problem since Julian Jerome is dead. Shawn's sure Vince was telling the truth. Sonny gets angry since Shawn let Vince go. Olivia wants to know what's going on as Shawn leaves. She doesn't think it's a stretch to believe Julian's alive after two people named Jerome moved to Port Charles. Sonny shares what he knows about Ava and is pleased that she wants to throw the kids a party. Olivia finds it poorly timed since they are burying Connie tomorrow. Sonny agrees to take his meds later but throws out the bottle when Olivia leaves.
Alexis interrogates Silas and Sam at GH when she catches them conversing privately. Silas admits they were making plans for dinner. Alexis and Silas try to sort out the differences they had before he saved Danny's life. He admits he couldn't have been more wrong in the way he handled things with Sam and Rafe. He knows now that Sam is a great mother. He doesn't believe he'd make a good parent. Sam tries to convince him otherwise after all the progress he's made with Rafe. She realizes he's worried about Kiki. He has to go and promises to call about dinner. Privately, Sam wonders if she's crazy for her interest in Silas but Alexis is glad she's putting herself out there even if Silas hasn't proven himself totally yet. Sam agrees, even if Silas isn't perfect like Derek Wells.
At the Metro Court, Carly and Felix wonder who's in Franco's room when Franco joins them outside his door. He doesn't want them to enter and Felix believes Franco has a prisoner in his room. Franco confesses it's a woman. Carly's angry but claims it doesn't matter to her since it's not like he would get a chance with her anytime soon. She says he can stay but he needs to provide a working credit card. She and Felix leave muttering about I told you so's. Franco brings Heather her BLT and asks her to leave for ruining his life. Carly now thinks he's a sleaze. Heather complains about the sandwich being pre-owned and cuts off the bitten part. She asks, "Who cares what Carly thinks?" She believes Franco dodged a bullet if Carly's not interested in him. Franco gets sappy dreaming about a normal life. Heather cheerily admits she still loves him.
At the pier, Derek's eager to get to the hospital but Ava reminds him that he's been given up to Sonny's goons. Derek's confident that Sonny believes 'Julian's' dead. Derek has a new identity and face. Sonny won't know what hit him. He needs Sonny out of the way when he hijacks his shipment. Ava brags about solving that problem. She and Sonny are having a party for their kids the same night. Derek's not happy to learn Ava met with Sonny against his wishes. Ava makes it clear that he's not her boss. Derek worries that Sonny could start to put two and two together. Nearby, Carly shushes Felix when she sees Derek and Ava. Felix asks why she's not saying hello. Carly can't stand Ava because the first time she laid eyes on her she was kissing Franco. Carly's certain Ava is up to something with Derek as sure as she was up to something with Franco before. Meanwhile, Ava knows about Sonny's bi-polar condition. Derek likes the sound of a mob-boss off his meds. She leaves and Derek hears a noise. Carly starts a fake argument with Felix and hits him as Derek finds them. Alone Felix wonders if Derek bought their story. Carly doesn't care. She thinks Derek needs to worry about if they bought his.
In the cabin, Kiki walks in on Morgan playing poker online. She announces she and Morgan have been voted off the Quartermaine property like Franco. Morgan wants her to ask Silas for help but she's not ready to get to know him. He's sorry the situation is so screwed up but doesn't think she can blame Silas for what happened with Franco. She agrees and answers the knock at the door. Silas is there to say hello. He's glad to see her since he can focus on other areas of his life now that Danny is better. Ava arrives and tries to convince Kiki to allow her and Sonny to throw them a party. Kiki doesn't trust her mother but Morgan thinks it's just a party. Kiki agrees if she can invite the father of the bride. Silas tells Kiki he will be there.
Derek meets Alexis and Sam at GH and is confident about something he is working on.
Tomorrow's Port Charles spoilers for General Hospital:
People who cross Maxie live to regret it.
Lulu meets with Anna about Maxie
Carly needs Spinelli to investigate someone.
Olivia tells Dante what Sonny was told about Julian Jerome.
Michael confronts Sonny about taking his meds.
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Financial Aid Office
Despite the fact that Walsh is one of the most competitively priced private Catholic universities in Ohio, we fully recognize the fact that finances may play an integral part in a student's ultimate enrollment decision. As a result, our financial aid staff will not only guide you through the financial aid application process, but are also available to counsel you on the various aid programs and to help you determine how these programs can best assist you in financing your educational expenses.
If you are a prospective student with questions about how we might be able to help you with your financial needs, please contact the Office of Admissions at (330) 490-7172.
Our financial aid office can be reached by calling (330) 490-7367.
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Isn't he cute? Or she. A little thick around the middle wouldn't you say? We had a nice trip through Amish Country. Its refreshing and beautiful, and I'm pretty convinced I could fit right in. Except I'd like a washer and dryer, and a hot water heater, and a microwave. I bought some cute fabric, mostly restocking favorites I'd used up, but I forgot to take a pic so that will come later.
I jumped on the band-wagon late, but I've decided to join Amanda Jean's 9 patch quilt along.
And of course another project, because I wouldn't feel complete without multiple unfinished projects in the sewing space.


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I wonder if it work with other cases and accessories
Capta mount gains Kickstarter funding, an all in one stand, cable management and tripod mount [video]
The Capta mount is an all in one stand, cable management and tripod mount designed for the iPhone and other smartphones. It has just received Kickstarter funding with double the pledges required and there are still seven days to go.
Designed by two freelance designers, Bojan Smiljanic and Adewale Adelusi-Adeluyi they set about originally creating a simple and elegant tripod mount. That has now expanded and the Capta can be used for many more things. The Capta is made from airplane grade aluminium and has a adhesive pad that can hold an iPhone securely. There is also a groove for cable management as well as threaded hole for a tripod attachment.
According to Smiljanic, "With the form factor and technology of smartphones always changing we designed Capta to be the hybrid accessory that could keep up with those changes. For example for iPhone users regardless of generation, Capta replaces the iPhone tripod mount, iPhone stand and iPhone cable management with one simple device. Capta has exceeded our original expectations and when paired with a suction cup or tripod mount the uses increase exponentially. We are humbled by how versatile Capta truly is."
If you want to be an early adopter, you can still head over to the Kickstarter page and make a pledge; $20 will get you a silver version. If you are really impressed, you could pledge the maximum $265 and get two exclusive black Capta's as well as a lot of extras too.
Source: Kickstarter
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Reader comments
Capta mount gains Kickstarter funding, an all in one stand, cable management and tripod mount [video]
I asked the same question because i have a 3gs as well and then i saw this test with 13 different phone sin their updates section. http://www.kickstarter.com/projects/1689824368/capta-stick-it-lean-it-wr...