text:
An expandable medical device has a plurality of elongated struts joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter. At least one of the plurality of struts includes at least one opening extending at least partially through a thickness of said strut. A beneficial agent is loaded into the opening within the strut in layers to achieve desired temporal release kinetics of the agent. Alternatively, the beneficial agent is loaded in a shape which is configured to achieve the desired agent delivery profile. A wide variety of delivery profiles can be achieved including zero order, pulsatile, increasing, decrease, sinusoidal, and other delivery profiles.
1. A method of forming an expandable medical device comprising:
(a) forming a substantially cylindrical expandable medical device body formed of a plurality of struts with a plurality of through openings in the plurality of struts;
(b) forming a first solution of a first beneficial agent, first polymer carrier, and a first solvent;
(c) delivering the first solution into the openings;
(d) evaporating the first solvent to form a solid layer of first beneficial agent and first carrier;
(e) repeating steps (c) and (d); and
(f) forming a second solution of a second beneficial agent, a second polymer carrier, and a second solvent and delivering the second solution into the openings on top of the layers of first beneficial agent, wherein the second beneficial agent is different from the first beneficial agent.
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This application is a continuation of pending U.S. application Ser. No. 10/729,631, filed Dec. 5, 2003, which is a continuation of pending U.S. application Ser. No. 09/948,989, filed Sep. 7, 2001, which claims priority under 35 U.S.C. �119(e) to U.S. Provisional Application Ser. No. 60/314,259, filed Aug. 20, 2001, which is incorporated herein by reference in its entirety.
1. Field of the Invention
The present invention relates to tissue-supporting medical devices, and more particularly to expandable, non-removable devices that are implanted within a bodily lumen of a living animal or human to support the organ and maintain patency, and that can deliver a beneficial agent to the intervention site.
2. Summary of the Related Art
In the past, permanent or biodegradable devices have been developed for implantation within a body passageway to maintain patency of the passageway. These devices are typically introduced percutaneously, and transported transluminally until positioned at a desired location. These devices are then expanded either mechanically, such as by the expansion of a mandrel or balloon positioned inside the device, or expand themselves by releasing stored energy upon actuation within the body. Once expanded within the lumen, these devices, called stents, become encapsulated within the body tissue and remain a permanent implant.
Known stent designs include monofilament wire coil stents (U.S. Pat. No. 4,969,458); welded metal cages (U.S. Pat. Nos. 4,733,665 and 4,776,337); and, most prominently, thin-walled metal cylinders with axial slots formed around the circumference (U.S. Pat. Nos. 4,733,665; 4,739,762; and 4,776,337). Known construction materials for use in stents include polymers, organic fabrics and biocompatible metals, such as, stainless steel, gold, silver, tantalum, titanium, and shape memory alloys such as Nitinol.
U.S. Pat. Nos. 4,733,665; 4,739,762; and 4,776,337 disclose expandable and deformable interluminal vascular grafts in the form of thin-walled tubular members with axial slots allowing the members to be expanded radially outwardly into contact with a body passageway. After insertion, the tubular members are mechanically expanded beyond their elastic limit and thus permanently fixed within the body. U.S. Pat. No. 5,545,210 discloses a thin-walled tubular stent geometrically similar to those discussed above, but constructed of a nickel-titanium shape memory alloy ("Nitinol"), which can be permanently fixed within the body without exceeding its elastic limit. All of these stents share a critical design property: in each design, the features that undergo permanent deformation during stent expansion are prismatic, i.e., the cross sections of these features remain constant or change very gradually along their entire active length. These prismatic structures are ideally suited to providing large amounts of elastic deformation before permanent deformation commences, which in turn leads to sub-optimal device performance in important properties including stent expansion force, stent recoil, strut element stability, stent securement on delivery catheters, and radiopacity.
U.S. Pat. No. 6,241,762, which is incorporated herein by reference in its entirety, discloses a non-prismatic stent design which remedies the above mentioned performance deficiencies of previous stents. In addition, preferred embodiments of this patent provide a stent with large, non-deforming strut and link elements, which can contain holes without compromising the mechanical properties of the strut or link elements, or the device as a whole. Further, these holes may serve as large, protected reservoirs for delivering various beneficial agents to the device implantation site.
Of the many problems that may be addressed through stent-based local delivery of beneficial agents, one of the most important is restenosis. Restenosis is a major complication that can arise following vascular interventions such as angioplasty and the implantation of stents. Simply defined, restenosis is a wound healing process that reduces the vessel lumen diameter by extracellular matrix deposition and vascular smooth muscle cell proliferation, and which may ultimately result in renarrowing or even reocclusion of the lumen. Despite the introduction of improved surgical techniques, devices and pharmaceutical agents, the overall restenosis rate is still reported in the range of 25% to 50% within six to twelve months after an angioplasty procedure. To treat this condition, additional revascularization procedures are frequently required, thereby increasing trauma and risk to the patient.
Some of the techniques under development to address the problem of restenosis include irradiation of the injury site and the use of conventional stents to deliver a variety of beneficial or pharmaceutical agents to the wall of the traumatized vessel. In the latter case, a conventional stent is frequently surface-coated with a beneficial agent (often a drug-impregnated polymer) and implanted at the angioplasty site. Alternatively, an external drug-impregnated polymer sheath is mounted over the stent and co-deployed in the vessel.
While acute outcomes from radiation therapies appeared promising initially, long term beneficial outcomes have been limited to reduction in restenosis occurring within a previously implanted stent, so-called 'in-stent' restenosis. Radiation therapies have not been effective for preventing restenosis in de novo lesions. Polymer sheaths that span stent struts have also proven problematic in human clinical trials due to the danger of blocking flow to branch arteries, incomplete apposition of stent struts to arterial walls and other problems. Unacceptably high levels of MACE (Major Adverse Cardiac Events that include death, heart attack, or the need for a repeat angioplasty or coronary artery bypass surgery) have resulted in early termination of clinical trials for sheath covered stents.
Conventional stents with surface coatings of various beneficial agents, by contrast, have shown promising early results. U.S. Pat. No. 5,716,981, for example, discloses a stent that is surface-coated with a composition comprising a polymer carrier and paclitaxel (a well-known compound that is commonly used in the treatment of cancerous tumors). The patent offers detailed descriptions of methods for coating stent surfaces, such as spraying and dipping, as well as the desired character of the coating itself: it should "coat the stent smoothly and evenly" and "provide a uniform, predictable, prolonged release of the anti-angiogenic factor." Surface coatings, however, can provide little actual control over the release kinetics of beneficial agents. These coatings are necessarily very thin, typically 5 to 8 microns deep. The surface area of the stent, by comparison is very large, so that the entire volume of the beneficial agent has a very short diffusion path to discharge into the surrounding tissue.
Increasing the thickness of the surface coating has the beneficial effects of improving drug release kinetics including the ability to control drug release and to allow increased drug loading. However, the increased coating thickness results in increased overall thickness of the stent wall. This is undesirable for a number of reasons, including increased trauma to the vessel wall during implantation, reduced flow cross-section of the lumen after implantation, and increased vulnerability of the coating to mechanical failure or damage during expansion and implantation. Coating thickness is one of several factors that affect the release kinetics of the beneficial agent, and limitations on thickness thereby limit the range of release rates, durations, and the like that can be achieved.
In addition to sub-optimal release profiles, there are further problems with surface coated stents. The fixed matrix polymer carriers frequently used in the device coatings typically retain approximately 30% of the beneficial agent in the coating indefinitely. Since these beneficial agents are frequently highly cytotoxic, sub-acute and chronic problems such as chronic inflammation, late thrombosis, and late or incomplete healing of the vessel wall may occur. Additionally, the carrier polymers themselves are often highly inflammatory to the tissue of the vessel wall. On the other hand, use of bio-degradable polymer carriers on stent surfaces can result in the creation of "virtual spaces" or voids between the stent and tissue of the vessel wall after the polymer carrier has degraded, which permits differential motion between the stent and adjacent tissue. Resulting problems include micro-abrasion and inflammation, stent drift, and failure to re-endothelialize the vessel wall.
Another significant problem is that expansion of the stent may stress the overlying polymeric coating causing the coating to plastically deform or even to rupture, which may therefore effect drug release kinetics or have other untoward effects. Further, expansion of such a coated stent in an atherosclerotic blood vessel will place circumferential shear forces on the polymeric coating, which may cause the coating to separate from the underlying stent surface. Such separation may again have untoward effects including embolization of coating fragments causing vascular obstruction.
In view of the drawbacks of the prior art, it would be advantageous to provide a stent capable of delivering a relatively large volume of a beneficial agent to a traumatized site in a vessel while avoiding the numerous problems associated with surface coatings containing beneficial agents, without increasing the effective wall thickness of the stent, and without adversely impacting the mechanical expansion properties of the stent.
It would further be advantageous to have such a stent, which also significantly increases the available depth of the beneficial agent reservoir.
It would also be advantageous to have methods of loading various beneficial agents or combinations of beneficial agents into these deep reservoirs, which provided control over the temporal release kinetics of the agents.
In accordance with one aspect of the invention, an expandable medical device includes a plurality of elongated struts, said plurality of elongated struts joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter, said plurality of struts each having a strut width in a circumferential direction and a strut thickness in a radial direction, at least one opening in at least one of the plurality of struts, and at least one beneficial agent provided in the at least one opening in a plurality of layers.
In accordance with a further aspect of the present invention, an expandable medical device includes a plurality of elongated struts, said plurality of elongated struts joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter, said plurality of struts each having a strut width in a circumferential direction and a strut thickness in a radial direction, at least one opening in at least one of the plurality of struts, and at least one beneficial agent provided in the at least one opening. A shape of the beneficial agent is configured to achieve a desired agent delivery profile.
In accordance with another aspect of the present invention, an expandable medical device for treating cardiac arrhythmias includes an expandable cylindrical device having a plurality of struts, a plurality of openings in the plurality of struts, and a chemically ablative agent provided in the openings. The openings are configured to deliver the chemically ablative agent to tissue surrounding the expandable cylindrical device without permanently trapping any agent in the openings.
In accordance with an additional aspect of the present invention, an expandable medical device for treating cardiac arrhythmias includes an expandable cylindrical device having a plurality of struts, a plurality of openings in the plurality of struts, and an anti-arrhythmic drug and a non-biodegradable carrier provided in the openings. The openings are configured to deliver the anti-arrhythmic drug to tissue surrounding the cylindrical device over an extended time period.
In accordance with another aspect of the present invention, a method of forming an expandable medical device includes providing an expandable medical device with a plurality of struts, said plurality of struts joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter, forming at least one opening in at least one of the plurality of struts, and delivering at least one beneficial agent into in the at least one opening in a plurality of layers.
The invention will now be described in greater detail with reference to the preferred embodiments illustrated in the accompanying drawings, in which like elements bear like reference numerals, and wherein:
Referring to
Formed between the slots 16 is a network of axial struts 18 and links 22. The struts 18 and links 22 are provided with openings for receiving and delivering a beneficial agent. As will be described below with respect to
Each individual strut 18 is preferably linked to the rest of the structure through a pair of reduced sections 20, one at each end, which act as stress/strain concentration features. The reduced sections 20 of the struts function as hinges in the cylindrical structure. Since the stress/strain concentration features are designed to operate into the plastic deformation range of generally ductile materials, they are referred to as ductile hinges 20. The ductile hinges 20 are described in further detail in U.S. Pat. No. 6,241,762, which has been incorporated herein by reference.
With reference to the drawings and the discussion, the width of any feature is defined as its dimension in the circumferential direction of the cylinder. The length of any feature is defined as its dimension in the axial direction of the cylinder. The thickness Of any feature is defined as the wall thickness of the cylinder.
The presence of the ductile hinges 20 allows all of the remaining features in the tissue supporting device to be increased in width or the circumferentially oriented component of their respective rectangular moments of inertia—thus greatly increasing the strength and rigidity of these features. The net result is that elastic, and then plastic deformation commence and propagate in the ductile hinges 20 before other structural elements of the device undergo any significant elastic deformation. The force required to expand the tissue supporting device 10 becomes a function of the geometry of the ductile hinges 20, rather than the device structure as a whole, and arbitrarily small expansion forces can be specified by changing hinge geometry for virtually any material wall thickness. The ability to increase the width and thickness of the struts 18 and links 22 provides additional area and depth for the beneficial agent receiving openings.
In the preferred embodiment of
The ductile hinge 20 illustrated in
Although a tissue supporting device configuration has been illustrated in
As shown in
The behavior of the struts 18 in bending is analogous to the behavior of an I-beam or truss. The outer edge elements 32 of the struts 18, shown in
The openings 24, 26 in the struts 18 may promote the healing of the intervention site by promoting regrowth of the endothelial cells. By providing the openings 24, 26 in the struts, 18, the cross section of the strut is effectively reduced without decreasing the strength and integrity of the strut, as described above. As a result, the overall distance across which endothelial cell regrowth must occur is also reduced to approximately 0.0025–0.0035 inches, which is approximately one-half of the thickness of a conventional stent. It is further believed that during insertion of the expandable medical device, cells from the endothelial layer may be scraped from the inner wall of the vessel by the openings 24, 26 and remain therein after implantation. The presence of such endothelial cells would thus provide a basis for the healing of the vessel wall.
The openings 24, 26 are loaded with an agent, most preferably a beneficial agent, for delivery to the vessel wall which the tissue supporting device 10 is supporting.
The terms "agent" and "beneficial agent" as used herein are intended to have their broadest possible interpretation and are used to include any therapeutic agent or drug, as well as inactive agents such as barrier layers or carrier layers. The terms "drug" and "therapeutic agent" are used interchangeably to refer to any therapeutically active substance that is delivered to a bodily conduit of a living being to produce a desired, usually beneficial, effect. The present invention is particularly well suited for the delivery of antiproliferatives (anti-restenosis agents) such as paclitaxel and rapamycin for example, and antithrombins such as heparin, for example.
The beneficial agents used in the present invention include classical small molecular weight therapeutic agents commonly referred to as drugs including all classes of action as exemplified by, but not limited to: antiproliferatives, antithrombins, antiplatelet, antilipid, anti-inflammatory, and anti-angiogenic, vitamins, ACE inhibitors, vasoactive substances, antimitotics, metello-proteinase inhibitors, NO donors, estradiols, anti-sclerosing agents, alone or in combination. Beneficial agent also includes larger molecular weight substances with drug like effects on target tissue sometimes called biologic agents including but not limited to: peptides, lipids, protein drugs, enzymes, oligonucleotides, ribozymes, genetic material, prions, virus, bacteria, and eucaryotic cells such as endothelial cells, monocyte/macrophages or vascular smooth muscle cells to name but a few examples. Other beneficial agents may include but not be limited to physical agents such as microspheres, microbubbles, liposomes, radioactive isotopes, or agents activated by some other form of energy such as light or ultrasonic energy, or by other circulating molecules that can be systemically administered.
The embodiment of the invention shown in
At intervals along the neutral axis of the struts 18, at least one and more preferably a series of openings 24′ are formed by laser drilling or any other means known to one skilled in the art. Similarly, at least one and preferably a series of openings 26′ are formed at selected locations in the links 22. Although the use of openings 24′, 26′ in both the struts 18 and links 22 is preferred, it should be clear to one skilled in the art that openings could be formed in only one of the struts and links. In the illustrated embodiment, the openings 24′ in the struts 18 are generally rectangular whereas the openings 26′ in the links 22 are polygonal. It should be apparent to one skilled in the art, however, that openings of any geometrical shape or configuration could of course be used, and that the shape of openings 24, 24′ may be the same or different from the shape of openings 26, 26′, without departing from the scope of the present invention. As described in detail above, the openings 24′, 26′ may be loaded with an agent, most preferably a beneficial agent, for delivery to the vessel in which the tissue support device 100 is deployed. Although the openings 24′, 26′are preferably through openings, they may also be recesses extending only partially through the thickness of the struts and links.
The relatively large, protected openings 24, 24′, 26, 26′, as described above, make the expandable medical device of the present invention particularly suitable for delivering agents having more esoteric larger molecules or genetic or cellular agents, such as, for example, protein drugs, enzymes, antibodies, antisense oligonucleotides, ribozymes, gene/vector constructs, and cells (including but not limited to cultures of a patient's own endothelial cells). Many of these types of agents are biodegradable or fragile, have a very short or no shelf life, must be prepared at the time of use, or cannot be pre-loaded into delivery devices such as stents during the manufacture thereof for some other reason. The large through-openings in the expandable device of the present invention form protected areas or receptors to facilitate the loading of such an agent either at the time of use or prior to use, and to protect the agent from abrasion and extrusion during delivery and implantation.
The volume of beneficial agent that can be delivered using through openings is about 3 to 10 times greater than the volume of a 5 micron coating covering a stent with the same stent/vessel wall coverage ratio. This much larger beneficial agent capacity provides several advantages. The larger capacity can be used to deliver multi-drug combinations, each with independent release profiles, for improved efficacy. Also, larger capacity can be used to provide larger quantities of less aggressive drugs and to achieve clinical efficacy without the undesirable side-effects of more potent drugs, such as retarded healing of the endothelial layer.
Through openings also decrease the surface area of the beneficial agent bearing compounds to which the vessel wall surface is exposed. For typical devices with beneficial agent openings, this exposure decreases by a factors ranging from about 6:1 to 8:1, by comparison with surface coated stents. This dramatically reduces the exposure of vessel wall tissue to polymer carriers and other agents that can cause inflammation, while simultaneously increasing the quantity of beneficial agent delivered, and improving control of release kinetics.
In a typical embodiment, the total depth of the opening 24 is about 125 to about 140 microns, and the typical layer thickness would be about 2 to about 50 microns, preferably about 12 microns. Each typical layer is thus individually about twice as thick as the typical coating applied to surface-coated stents. There would be at least two and preferably about ten to twelve such layers in a typical opening, with a total beneficial agent thickness about 25 to 28 times greater than a typical surface coating. According to one preferred embodiment of the present invention, the openings have an area of at least 5�10−6 square inches, and preferably at least 7�10−6 square inches.
Since each layer is created independently, individual chemical compositions and pharmacokinetic properties can be imparted to each layer. Numerous useful arrangements of such layers can be formed, some of which will be described below. Each of the layers may include one or more agents in the same or different proportions from layer to layer. The layers may be solid, porous, or filled with other drugs or excipients.
The advantage of complete erosion using the through openings over surface coated stents opens up new possibilities for stent-based therapies. In the treatment of cardiac arrhythmias, such as atrial fibrillation both sustained and paroxysmal, sustained ventricular tachycardia, super ventricular tachycardia including reentrant and ectopic, and sinus tachycardia, a number of techniques under development attempt to ablate tissue in the pulmonary veins or some other critical location using various energy sources, e.g. microwaves, generally referred to as radio-frequency ablation, to create a barrier to the propagation of undesired electrical signals in the form of scar tissue. These techniques have proven difficult to control accurately. A stent based therapy using through openings, biodegradable carriers, and associated techniques described herein could be used to deliver a chemically ablative agent in a specific, precise pattern to a specific area for treatment of atrial fibrillation, while guaranteeing that none of the inherently cytotoxic ablating agent could be permanently trapped in contact with the tissue of the vessel wall.
If, on the other hand, the goal of a particular therapy is to provide a long term effect, beneficial agents located in openings provide an equally dramatic advantage over surface coated devices. In this case, a composition comprising a beneficial agent and a non-biodegradable carrier would be loaded into the through openings, preferably in combination with a diffusion barrier layer as described below. To continue the cardiac arrhythmias example, it might be desirable to introduce a long-term anti-arrhythmic drug near the ostia of the pulmonary veins or some other critical location. The transient diffusion behavior of a beneficial agent through a non-biodegradable carrier matrix can be generally described by Fick's second law:
Beneficial agent that is released to the radially innermost or inwardly facing surface known as the lumen facing surface of an expanded device may be rapidly carried away from the targeted area, for example by the bloodstream, and thus lost. Up to half of the total agent loaded in such situations may have no therapeutic effect due to being carried away by the bloodstream. This is probably the case for all surface coated stents as well as the through opening device of
Barrier layers can be used to control beneficial agent release kinetics in more sophisticated ways. A barrier layer 52 with a pre-determined degradation time could be used to deliberately terminate the beneficial agent therapy at a pre-determined time, by exposing the underlying layers to more rapid biodegradation from both sides. Barrier layers can also be formulated to be activated by a separate, systemically applied agent. Such systemically applied agent could change the porosity of the barrier layer and/or change the rate of biodegradation of the barrier layer or the bulk beneficial agent carrier. In each case, release of the beneficial agent could be activated by the physician at will by delivery of the systemically applied agent. A further embodiment of physician activated therapy would utilize a beneficial agent encapsulated in micro-bubbles and loaded into device openings. Application of ultrasonic energy from an exterior of the body could be used to collapse the bubbles at a desired time, releasing the beneficial agent to diffuse to the outwardly facing surface of the reservoirs. These activation techniques can be used in conjunction with the release kinetics control techniques described herein to achieve a desired drug release profile that can be activated and/or terminated at selectable points in time.
Alternatively, different layers could be comprised of different beneficial agents altogether, creating the ability to release different beneficial agents at different points in time, as shown in
A further alternative is illustrated in
Another general method for controlling beneficial agent release kinetics is to alter the beneficial agent flux by changing the surface area of drug elution sources as a function of time. This follows from Fick's First Law, which states that the instantaneous molecular flux is proportional to surface area, among other factors:
In the embodiment of
A second general method for varying drug eluting surface area as a function of time is to change the shape or cross-sectional area of the drug-bearing element along the axis of the opening.
The changing cross section openings 70 of
The process of preforming the beneficial agent plug 82 to a special shape, inserting in a through opening, and back-filling with a second material can yield more complex release kinetics as well.
An alternative embodiment of
In the embodiment of
While the invention has been described in detail with reference to the preferred embodiments thereof, it will be apparent to one skilled in the art that various changes and modifications can be made and equivalents employed, without departing from the present invention.
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We had a great day at the zoo!!! Here are some highlights!
All of the kids together
(from left to right is Hunter standing, then Dalton in his stroller, Will standing leaning in with Ethan in his stroller. Thats Stephan out front in the wagon, then you have Andrew and Elizabeth standing then Grace sitting on the ground)
All of the Mommies together
(from left to right: Meg, Jennifer, Lori, Cassie)
Elizabeth, Will and Andrew of the Elephant
Hunter, WIll and Andrew playing with their animal toys from the gift shop
Dalton with the cutest little curls you have ever seen!
Will, Elizabeth and Andrew in the penguin cave. (yes, they were sweating THAT much!)

subset: commoncrawl


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Front Skirt Pleated Dress
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With leather straps and a drop-waist A-line skirt, this bebe dress offers an edgy and flirty take on the classic little black dress. Try it with a pair of studded pumps to finish the look.
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- Center back to hem: 37" (94 cm)
- Leather Contrast
- Jersey lining
- Invisible zipper
- Dry clean
- Imported
- Model is 5'9" and is wearing a US size S


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The following graphic compares the cost of living between Coatzacoalcos, Mexico and the Acapulco, Mexico and assumes earnings of $50,000 in the base city.
If you are earning 50,000 Mexican Pesos in Coatzacoalcos, Mexico you would need to earn 48,364 Mexican Pesos in the Acapulco, Mexico to maintain the same standard of living.
Currency in Mexican Pesos


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Price: $40.00
The Gospels of the New Testament describe the life of Jesus of Nazareth, from his birth in Bethlehem and his travels through Galilee to his trial and death in Jerusalem. In the Footsteps of Jesus goes even deeper into the story of Jesus' life by following his path through the Holy Land on richly detailed maps and bringing each pivotal place to life through the latest archaeological and historical discoveries. Breathtaking photography and unique period artifacts complement fascinating text and specially created maps by National Geographic cartographers.
In the Footsteps of Jesus illustrates not only the stories of Jesus' life but also the characters and events that shaped his journey and ultimately made him one of the most famous figures the world has ever known. This compelling and beautiful book traces Jesus' path from Bethlehem to Nazareth; throughout his "mission triangle" of Lower Galilee and into the Decapolis; and ultimately on his journey to Jerusalem, the Garden of Gethsemane, and Golgotha.
Expertly crafted text describes what is known and speculated about Jesus' youth, life, and work while showing the larger events that combined to shape the world in which he lived. Both the text and sidebars describe the places in Jesus' world that can still be experienced by visitors, as well as key sites that have since disappeared but can be reconstructed by forensic means.
Captivating elements include quotes attributed to Jesus; historical data derived from Jewish sources such as the Mishnah, and Roman sources such as Josephus; census data and other documents; key facts, and insightful main text. Newcomers to biblical history as well as the devoted will find this an invaluable reference and a gorgeous book for the home library.
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By JEANNINE
from WELLSVILLE NEW YORK
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Comments about In the Footsteps of Jesus:
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More than footsteps
By Dick
from Silver Spring, MD
I thought this was a DVD when I ordered, but jumped right in reading when it arrived. Not really footsteps (since we can't quite know), but very good historical context to what was happening at this time.
Stunningly beautiful book!
By Mikee
from Minden, Nevada
About Me Casual Reader
It is an inspiring book, fascinating!
(1 of 1 customers found this review helpful)
In The Footsteps Of Jesus
By SparkleGreen
from Toronto, Ontario Canada
Engaging Photography, pleasing to the eyes. It captivated my attention from the beginning to the end of the book.
(6 of 6 customers found this review helpful)
Great History!
By altodeborah
from Alto, NM
I loved this book so much that I have already given one as a gift. Being able to put the history of what was going on at the time Jesus would have been alive is amazing! There are so many things in the Bible that are hard to understand without having the history! Loved it!
(4 of 4 customers found this review helpful)
Marvelous read
By Shirley Girl Two
from Dillsburg, Pa.
I'm not done reading this book yet as it is rather large but so far it is very interesting. I'm learning so much about our Lord, it is so interesting to see where He walked when He was on earth. When I start reading I have a terrible time putting it down, that's how interesting it is. Not only is it interesting but very knowledgeable. The photography is gorgeous.
Illuminating Book! Beautifully done!
By OWH
from Minneapolis, MN
Even though I wish I had seen this before I went to Israel it is a wonderful tool for reinforcing and giving considerable depth to that memorable personal experience.
(2 of 8 customers found this review helpful)
Book is fine, paper cover cut on 2 of 3
By Will not order anymore books with sleeve
from Ontario, CA
Like the maps and pictures
Bottom Line No, I would not recommend this to a friend
Extremely well written . Excellent !
By Jim the seeker
from Pueblo , Colorado
Affirmed my beliefs and faith .


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Calling all Ct Moms!! Connecting moms in the state of Ct for parenting advice, womens issues and support. Being connected makes a difference :)
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List your blog and Twitter ID here so we can follow each other. We need to get CT on the map!My Blog- http://rachelferrucci.comTwitter -…Continue
Started by Paola S. Kaoud. Last reply by Jean Myles Sep 24, 2010. 3 Replies 0 Likes
Critter Caravan is coming to Tickles.On Saturday September 25th, 2010 at 3:15 pm Kathryn from Critter Caravan will be visiting Tickles. Critter Caravan brings a wide assortment of exotic small…Continue
Started by Paola S. Kaoud Sep 8, 2010. 0 Replies 0 Likes
Critter Caravan is coming to Tickles.On Saturday September 25th, 2010 at 3:15 pm Kathryn from Critter Caravan will be visiting Tickles.Critter Caravan brings a wide assortment of exotic small…Continue
Started by Paola S. Kaoud. Last reply by Lisa Hawkins Jul 13, 2010. 2 Replies 0 Likes
Summer Festival & Sidewalk SaleSummer Festival & Sidewalk Sale This coming weekend is The 31st Annual Summer Festival and Sidewalk Salein historic downtown Bethel, featuring live music,…Continue
Hi, I'm Kristen. I'm new here, but also a CT blogger. My blog is called A Thrifter in Disguise and my Twitter handle is ThriftDisguise. I'm also looking to build up my Instagram community krosiepowers--if anyone else is on IG, follow me and I'll follow back!
To all CT Moms if your daughter loves fairytale princesses you need to read this post! I promise you it will be a day of you will soon not forget. Our show is enjoyed by all ages and the meet and greet is amazing. You can also have your birthday party at The Princess Place
The Princess Place
Hear Ye! Hear Ye!
It's the most magical place in the entire Connecticut Kingdom — The Princess Place…where a smile fills your heart.
The Princess Place delights in opening its Royal Doors on Saturday March 16th 2013 and welcomes one and all to this enchanting experience!
Take a step inside a magical carriage and a theatre filled with fairytale whimsy. Be charmed by this season's musical presentation, Eugenia, A Princess Story — The Bijou's very own reluctant princess.
After Eugenia takes the stage and as the royal bugle sounds, the storybook fantasies continue as guests of the kingdom are greeted by the Belles of the Ball. A missing glass slipper and a kiss from a true love bring all of these fairytale Princesses to life for individual photos and autographs with guests.
Saturdays beginning March 16th two performances each day at 11:00 AM and 2:30PM. Doors will open one half hour prior to each performance.
($20.00) Includes admission for one person. Applies to all ages and all seats.
(10% Discount) Groups of fifteen (15) or more who reserve theater or cabaret seating will receive a 10% discount off each ticket.
($15.00) Includes one (1) large popcorn, one (1) non-alcoholic drink, and one (1) princess crown.
Includes premiere cabaret seating, beverages, pizza, cupcakes and a Princess Birthday serenade. Email email@example.com pricing and availability.
To purchase tickets online click here. To inquire about a birthday party or make group reservations, please call the box office at 203-332-3228. See you at The Princess Place!
Welcome Lexi! Just stopped by and followed your blog! My blog is here: www.MommyToTwoBoys.com
Hi everyone!
I am looking for solutions to my storage problem. I created a link party in hopes that someone out there in blog land can help me. if you can please stop by.
Hi Everyone, I am a new blogger from CT. I am not a mom yet but will be soon ;)
check out my blog sometime
I'm a new blogger and a wilton, ct resident. Check out my blog at www.9monthsofstyle.net, I'm always looking for feedback!


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Our Approach
At Drupal Connect, we build brilliant web and mobile experiences for the likes of Sony, GE, NBC, Stanford, Harvard, and the UN. Why do such universally respected companies choose to work with us? Like most web firms, we provide design, development and consulting services. What sets us apart? We're the top Drupal development and support company in North America. And we're led and staffed by an integrated team that's adept at everything from performance to complex data migration to eCommerce and more.
Let us Drupal something for you. Contact us or view our work.


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Community Standards
Learn the Code. Live the Code.
In keeping with the Catholic, Jesuit, and humanistic philosophies, Gonzaga University holds a high standard of conduct for its students and community members. The spirit of Jesuit education is to consistently strive for the magis, meaning excellence in all that we do, and to do so with attention to the whole of a person—intellectual, spiritual, physical, and emotional. Gonzaga's expectations of conduct are designed to develop students into persons who lead lives of leadership and service for the common good. This is a high calling, beyond the basic standards of our society.
The Office of Community Standards provides resources, education, and processes regarding the University's conduct expectations. We strive to equip students with the capacity to respect the dignity of all members of the community, respond with honesty and integrity, and accept responsibility for their actions. We work to maintain a balance between individual needs and the Gonzaga University community.
The Student Handbook outlines expectations for student conduct and includes topics such as:
- University Standards, including policies such as:
Alcohol Policy
Drug Policy
Harassment and Anti-Discrimination Policy
Housing and Residence Life Policies
Prohibited Conduct
Sexual Harassment and Sexual Misconduct Policy
- University Resources
- University Conduct Process
Paula Smith
Director of Student Conduct
Jae Webb
Assistant Director of Student Conduct
Cortney Brewer
Conduct Specialist
Nicole Bucher
Program Assistant
Office of Community Standards
Crosby Center 202
Spokane, WA 99258-0094


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THIS WEEK: The New Mexico State baseball team faces Texas Tech in a single game Monday, March 25 before hitting the road, Thursday through Saturday, March 28-30, to play CSU-Bakersfield in a three-game WAC series.
Monday's game versus Texas Tech begins at 6:05 p.m. (MT). Thursday and Friday's games start 7:00 p.m. (MT) with the series finale against CSU-Bakersfield beginning at 2:00 p.m. (MT).
MEDIA COVERAGE: NM State baseball fans will have plenty of opportunities to follow their Aggies on the radio again this season with the voice of Aggie baseball, Jeff Matthews on KSNM AM 570. The Aggies are scheduled to broadcast 34 games this season, plus any in the post season.
The game against Texas Tech is scheduled to air on the radio in Las Cruces on KSNM AM 570, with Jeff Matthews.
Fans can also listen to the Texas Tech game live on the Internet by clicking on the live events link on www.NMStateSports.com for a fee.
Live stats are available all season long by going to www.NMStateSports.com and clicking on the live events tab. Live stats are free of charge all season.
SOCIAL MEDIA: Fans can keep up with score updates and other information by logging on to Twitter @NMStateAggies. Fans can find out about promotions and everything else Aggie by going on Facebook and searching for NMSU Athletics as well as The Aggie Student-Athlete.
PROMOTIONS: Monday night will be Baseball Bingo Night. Aggie fans are encouraged to head out to Presley Askew Field to win great Aggie prizes. Kid 12 and under get into the game free while adult tickets are only $6. Call 646-1420 to purchase your tickets or buy them at the ticket booth located at the ballpark.
MONDAY'S OPPONENT: The Aggies take on Texas Tech for the 56 time with TTU leading the series 39-16. NM State lost the most recent match-up, 12-7 in Las Cruces, May 1, 2012. According to the NM State media guide, the two teams first met in 1965.
MONDAY'S STARTING PITCHER: Sophomore left-hander Trey Higginbotham gets the start for the Aggies against Texas Tech on Monday. This will be just his second start of the year and career. His first career start came against Alabama A&M on March 16 when he worked 5.0 innings and struck out a career-high seven batters. The Aggies won 5-3 in the seven-inning affair while the two runs Higginbotham gave up were unearned.
PLAYERS TO WATCH: Senior center fielder Kyle Phillips hit .500 against Texas State last week going 6-of-12 at the dish. He posted two doubles and a home run while finishing the week with five RBI. Phillips has now boosted his batting average to .289 on the year with seven doubles, a triple and a home run. He has 12 RBI's and 26 runs scored this season while taking control of the Aggie defense in centerfield.
Senior infielder Bobby Lecount hit .417 in the weekend series against Texas State with a double, a home run and a .750 slugging percentage. He is hitting .358 on the season with a team-high five home runs and a team-high .593 slugging percentage. Lecount blasted a home run over the leftfield wall in the series finale against Texas State to tie the game 2-2 in the bottom of the first inning.


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Google Music Player is a Google Desktop gadget that lets you search and play the music from your computer. Google Desktop indexes your music, but the browser is not the best place to play your music. This gadget is an easy way to build a playlist by repeatedly searching for your favorite songs, to listen an album or all the songs that match your query.
Although the player is a pretty nice exercise, Google didn't read my post from May.
Workin' In A Cocktail Bar
4 hours ago


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Call Us Toll-Free @ 866-539-4278866-539-4278
Cart (0)
EuroGraphics is the leading distributor of art in North America. These jigsaw puzzles have incredible imagery of art history, American history, world history and even educational compilations.
Use the filters to the left or simply scroll down to begin viewing all pages.
Free shipping and flat rate offers for US only but excludes HI and AK.
Need to return or exchange a puzzle? It's easy. Simply call us at 866-539-4278 or email firstname.lastname@example.com to request a Return Authorization Number, and we will send you a prepaid return label for the item.
Please note:
Copyright © 2015, Puzzle Warehouse, All rights reserved. St. Louis Jigsaw Puzzles
Puzzle Warehouse recycles everything it can to save the environment and to keep costs and prices low.


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"Team loves the new jerseys. They are comfortable, light weight and nice looking. The price was awesome! We've only worn the jersey for 2 weeks so far so I know if colors will fade with continuous washings but they do clean up nicely. Grass stains and mud have come out in a single wash.
Sizes do run big. I am 5'5" and about 185lb. I ordered a large and I feel like I'm swimming in it (and I do like my shirts loose)
We ordered these shirts in "cardinal" color and I would recommend choosing a white or black sock to go with them rather than the "Cardinal" pro feet socks that I chose. Dye lots are definitely different." (E2162)
"great price,great for agility drills" (E1756)
"Very comfortable. Great fit." (E14519)
Epic Sports
Susan G. Komen Cure Soccer Balls (3,4,5) [E27315]


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Targets & Baskets :: Recreational Full Size
|View cart Checkout
The Ground Anchor for the Freedom and Liberty baskets is designed to keep your target secure while providing altnerate basket locations. Cement the anchor into the ground, and insert any in-ground-ready Freedom or Liberty (not included) for a padlock-ready... more
Number your Freedom or Liberty! For the extra iconic basket vibe or for course installations, we offer a number plate with sticker kit that allows each individual basket to be numbered 1-21 (includes vinyl numbers, "0-9" plus an additional "1" per kit). The... more
This Permanent Mount for the Freedom and Liberty baskets is designed to keep your target secure and allow easy relocation to another sleeve (extra sleeves sold separately as the Ground Anchor for Freedom and Liberty). Cement the lower section of the sleeve... more
Is the canvas shot on your Skillshot Shot? Then the Canvas Skillshot replacement skin is just what the doctor ordered. This item includes top and bottom canvas replacement skins for your Skillshot, and bears the "Innova" logo that appeared on the original... more


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Who has the prettiest bangs?
From Karlie Kloss to the FLOTUS, bold bangs keep cropping up everywhere. Can you guess, based on popular vote, who rocks the feathery effect best?
Your score: 0
Which star looks better with bangs?
See how many out of 20 you can get right. Score by clicking on the photo with the most votes.
Good luck!


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Through clever songs, sounds, and baby-friendly tools, The Talking Mechanic car teaches Baby about the different parts on a car, and how to fix it! This interactive bilingual toy comes complete with two tools that help kids develop hand-eye coordination. With 50+ activities, the Talking Mechanic is sure to fascinate and delight young ones! Includes 3 play modes:
- 1. Engine sounds: real-life engine sounds to make playing with the vehicle even more enjoyable.
- 2. Sing and learn: songs, sound effects and phrases that invite toddlers to "fix" certain vehicle components and learn how to identify car parts in English and Spanish.
- 3. Quizzes: entertaining sound effects, riddles and quiz questions on colors, shapes, the alphabet and numbers.
- Requires: 2 x AA 1.5V batteries (included)
- Age: 2Y+


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choose a subscription:
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Weekend shooting drug related
HUNTINGTON — A Saturday night shooting was a drug-related, targeted incident between a teenage victim and assailants known to each other, according to a Monday afternoon update provided by Huntington Police Lt. John Williams.
The victim, 17, remained sedated and seriously injured Monday afternoon with three gunshot wounds, but her condition is improving, Williams said.
Anyone with more information about the incident should call Huntington Police at 304-696-4444.
The incident occurred just before 10 p.m. Saturday at the intersection of 19th Street and West 5th Avenue. Police responded to the scene and found the girl, whose name was not released, on the ground in the middle of the intersection, according to Huntington Police Lt. John Williams. She had suffered multiple gunshot wounds to her upper body.
Rumors that the girl was found naked in the intersection are not true, Williams said. She was taken to a local hospital, where she underwent surgery early Sunday.
The girl, a Huntington resident, had spent much of the evening at a friend's house about a half-block east of the shooting, Williams said. The girl told her friends she had to leave the house to do something and would be back. A few minutes later, the girl's friends heard gunshots, Williams said.
"Her friends said she hasn't had problems with anyone recently," Williams said. "No one really knows why or they're not saying."
Williams said early Sunday evening that the girl was sedated and in intensive care at a local hospital.
"I'm sure she will be able to clarify a lot of things," Williams said. "We're kind of in a holding pattern until we can interview her and figure out which way to go with this."
A handgun and shell casings were found at the scene, and motorists who were driving through the intersection during the shooting provided a general description of two suspects, Williams said.
They are described as a black male and a white male. Both are believed to be in their teens with average builds and wearing dark clothing at the time of the incident. They fled south on foot, Williams said.
Anyone with information is asked to call the Police Department at 304-696-4444.
Follow H-D reporter Bryan Chambers on Facebook or Twitter @BryanChambersHD.
The Herald-Dispatch welcomes your comments on this article, but please be civil. Avoid profanity, obscenity, personal attacks, accusations of criminal activity, name-calling or insults to the other posters. Herald-dispatch.com does not control or monitor comments as they are posted, but if you find a comment offensive or uncivil, hover your mouse over the comment and click the X that appears in the upper right of the comment. If you do not want your comment to post to your personal Facebook page, uncheck the box below the comment.


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Standard Issue Ladies
|White Dial / Bi-Color Bracelet
|» More Images
Swiss quartz
100m (330 ft.)
Stainless steel
Hands and markers
Date display
18K PVD gold-plated accents
3-Year limited warranty
3-Link stainless steel bracelet
Diver's buckle and safety clasp
Dont let the name fool you. Theres nothing standard about this collection. One of the first watches Wenger ever made, the Standard Issue quickly became a signature series. A quick look at the Standard Issue Ladies 70609 demonstrates why it remains so today. Clearly, classic style enjoys longevity. Especially when enhanced by meticulous redesign, resulting in a series that is literally bigger and more impressive than its worthy predecessor.
Learn more about the PVD process.
Standard Issue Ladies 70609 Swiss Watch. Check out all Wenger Swiss Watches.
Product Specifications
Product Manual
Standard Manual (2 MB pdf file)
More About This Item


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Buy with confidence
- Money-back Guarantee
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- Superb Customer Service
More from Intelligent Nutrients
Chill without pills. Sweet orange, white grapefruit and mandarin are used to create a soothing combination as they mingle with warm, tranquil floral notes of neroli and petigrain. This multifunctional certified organic oil uses our Intellimune seed oil and other essential oils to take care of the cells and the system while it makes skin smooth. And that's sexy. Completely free of mineral oil or other petrochemicals. Also available in certified organic mist form for daily personal aroma. Smells like: A clean citrus by way of Morocco. Feels like: You actually do manage to meditate-and just did.


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View my Wish List
$ 65.00
Available at local Chamilia retailers.
Add to Wish List
Article no.: 2083-0456
Sterling Silver,
Crystals and Stones
Just like flowers plucked from the garden, the Daisy Bouquet bead adds whimsy and color to your jewelry. The floral design sparkles in red and yellow crystal.
Jeweled Kaleidoscope Bead - Yellow Swarovski
$ 70.00
Royal Petals - Red And Yellow Bead
$ 75.00


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The improvements are nice but useless without cross platform support. I mean, so useless as to actually irritate me. Photo Stream means nothing without being able to translate to something view-able on Android and PCs.
App. web app (blech), web site; something needs to make this accessible to people's friends who use Android. The people who I want to share with are a mix between feature phones, iPhones, and Android devices (and I expect that I am far, far from alone there). Using Photo Stream would mean I'd need to share twice and have responses in two different spots.
At least iMessage is baked in to SMS. But already there I've switched to Google Hangouts for a lot of conversing because so many of my friends have different ways of communicating that Apple won't address.


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Karate Instructor
- Join Date
- Jul 2003
- Posts
- 196
Posted On:
7/11/2003 1:34am
I orginally hail from Knoxville, Tennessee. The martial arts community is pretty much 50% Karate, 40% TKD, and 10% Kung Fu. The Karate Community is a dabbling of everything, but Isshinryu is a big one there. There are tiny pockets of other styles and arts, like jujutsu, judo, and kendo, but no formal schools.
Now that I am here in Charleston SC, there is a tiny Isshinryu school (YAY ME!) very few Karate dojos, and a TKD school on every street corner. There are also a few small schools that teach Judo and other ground arts, but that is about it.
- Join Date
- Jan 2003
- Posts
- 538
Posted On:
7/11/2003 2:00am--
Hey Rising Phoenix, where are you staying in Japan?
Getting to Phrost's questions:
*In my immediate neigborhood there are karate, aikido, kendo, and kyudo dojos, and the local university has karate, aikido, kendo, judo, and sumo. Over the city there's probably more karate and aikido than anything else.
*Looking at Tokyo as a whole, you can find anything at all. Japanese, Chinese, Western, Brazilian, Shootfighting, whatever.
*I would guess about 5% of adult males train, maybe 1% of women. However, most boys practiced either judo or kendo at school.
Taking a break
- Join Date
- Oct 2002
- Location
- Bolton, Lancashire, UK
- Posts
- 2,611
Posted On:
7/11/2003 2:30am--
Manchester - England
Damn near every style you can imagine within 50 miles of it. Aikido is way too common, esp. as its mostly the flower arranging style.
WC and MT are both big, karate and tkd have lots of small clubs. There are some big MMA clubs as well. Also lots of fencing and archery, boxing, amateur wrestling and some pro wrestling (very different to USA pro wrestling though)Taking responsibility for my actions since 1989
Badness will not be rewarded
- Join Date
- Apr 2003
- Location
- Montreal, Canada
- Posts
- 4,839
Posted On:
7/11/2003 6:05am--
Hamburg, Germany
Tons of WT/WC/VT - about 40% I would say. 30% Judo and 20% Ju-Jitsu. Only about 10% BJJ, MT, MMA.
My school is only one of 2 (affiliated schools) that teach BJJ. We also do Shooto, JKD, Sambo, Boxing, and Ju-Jitsu.
Probably only about 3% of the people in my area do MA. TKD schools are relatively rare.
Registered Member
- Join Date
- Jul 2003
- Posts
- 2
Posted On:
7/11/2003 8:15am
Phrost I wanted to get a picture of our members, and the environment in which they live, specifically when it comes to martial arts.
*What part of the country do you live in?"
Washington DC Metro/Central VA
*What's the distribution of MA schools in your area, with a rough percentage of the arts represented?
I'm a newbie, but in 30 mile radius from my house there isn't much. mostly TKD (60%), karate, 1 aikido - supposedly very good, just not convinent for me.
But, from a 30 mile radius from DC there are many options... again mostly TKD (thanks to Jun Ree(sp?) :P ), and karate, aikido, kungfu (downtown), and even a coupla Ninjitsu/Taijutsu schools...
Note: I haven't done a thorough investigation so all of this could be way off.
*Are there any unique/uncommon martial arts offered in your area besides the normal TKD/Karate/etc, including MMA/NHB fight teams?
see above, there could be...
*If you had to guess (unless you know for some reason) what percentage of people in the general community in your area are active participants in the martial arts?
Bad guess - 5%, alot of kids... part of the reason I signed up at the local Ishinryu school, my 9 year old has been enrolled for 2 years now. He's getting to the point where I couldn't help him out at home (pratice, pratice, pratice) I thought it best to learn with him.
Community Corrections Officer
- Join Date
- Jun 2003
- Location
- Spokane, WA
- Posts
- 3,621
Posted On:
7/11/2003 8:46am--
Orlando, FL.
There's a huge slew of tkd/karate McDojos (heck, they hold ISKA comps here). Probably 90%. But there's actually a couple nhb/mma type schools here, maybe 5%, 4% other (a kungfu place and a couple Aikido Dojos) and there's one Judo school. That's all off the top of my head, of course.
There's Marcio Simas BJJ (a Gracie Barra school), there's some other BJJ school supposedly too, but I don't know anything about it. Then there's Kokopeli's Kickboxing that has BJJ, Muay Thai, Boxing, submission grappling, etc. And Din Thomas used to have a school here too, though I'm not sure if it's currently in operation or not. There's also a JKD place. And there's at least 1 Kyokushin place around here too.
And I have no idea what percent of the population does MA.
"My cat's name is Mittens."
Ralph Wiggum
Registered Member
- Join Date
- Nov 2002
- Posts
- 467
Posted On:
7/11/2003 8:59am
Style: Aikido and Judo--
South West England.
A high proportion of Karate and TKD. Some Aikido and Judo places. A growing community of MMA and BJJ type MA's. Very little in the way of Chinese arts.
As for unique systems I not all that sure. But the quality of the teaching varies hugely from school to school.
I would say a very small percentage something like 0.5% are involved in MA. Unfortunately there are a lot of Kids in some schools, just not mine. phew.
Registered Member
- Join Date
- Jun 2003
- Posts
- 35
Posted On:
7/11/2003 2:03pm
What the hell, I'm still laid up and I could use a little home work.
According to my local Sacramento, CA Valley Area Yellow pages there are 80 some odd martial arts schools in my area. They break down as follows:
Karate- 13
Kung fu- 9
Kenpo- 7
Miscellanous (no art identified)- 7
Judo- 4
Kick Boxing- 2
Judo- 2
Boxing- 1
Capoeria- 1
Fencing- 1
I found 17 schools that advertised more than one art.
I found it funny that there were 7 schools that had generic names like XYZ Martial Arts Academey and basically gave no infromation on what they taught.
The closest thing to a chain I found was a karate school that have four locations, although that couble be misleading because my school (Kenpo/Wing Chun) has two studios and 5 park and recreation programs but only one number listed in the phone book.
<marquee>Dragon , Snake , Tiger , Leopard , Crane. R.M.F.A.F.T.A.T.! </marquee>


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Eunice Marie Mayo was born January 28, 1917 in Snow to Robert Lee and Verna Bell (Chapman) Joslin. She passed from this life April 12, 2011 in Antlers at the age of 94. Eunice married Albert Mayo on October 16, 1945 in Paris, TX. Eunice, affectionately known as Granny to most people, was of the Baptist faith and was a member of Ethel Missionary Baptist Church. She enjoyed quilting, gardening, and general yardwork. She loved spending time with family and friends. Eunice was preceded in death by her husband: Albert Mayo; son: David Joslin; four stepsons; one stepdaughter; parents: Robert & Verna Joslin; four brothers and four sisters. She is survived by her son: Dwight Mayo of Antlers; step-daughter: Leona Boyd & husband Willie Ray of LA; daughters-in-law: Louise Mayo of Ft. Worth, TX; Peggy Joslin of Antlers; brother: Johnny Joslin & wife June of Oklahoma City; sister: Helen Stobaugh & husband Fred of McAlester; numerous grandchildren; as well as many other relatives and friends. Graveside services were held at 10:00 a.m. on Friday, April 15, 2011 with Reverend Gerald Joslin officiating. Musical selections included: "Lily Of The Valley" and "The Old Rugged Cross" Performed by: Reverend Gerald Joslin. Internment followed at the Finley Cemetery in Finley. Family and friends may send online condolences at www.millscoffey.com [1].
Funeral services conducted by
Mills & Coffey Funeral Home in Antlers
[1] http://www.millscoffey.com


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Photo Albums > Parenting Diary
Parenting Diary (Feet)
Artist name
- Saori Otsuka
Release date
- 2008-11-28
< Set the printer >
Recommended paper type
- Matte Photo Paper
Print Quality
- High
- Portrait
Page Layout
- Borderless
Page Scaling
- None
You can arrange photos and print them out easily by referring to "How to make scrapbooks using photo frames" from the Help section. Alternatively, stick photos you have printed out (4"x6" in size) in your parenting diary directly.
This parenting diary lets you enjoy recording the growth of your baby with photos and comments of memories from Mom and Dad! Place your favorite photos to make a special diary that will turn into a wonderful memory for you and your family! *Place a photo of your baby's cute, tiny feet.


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Department of Human Resources
The following vacancy exists in the Sheboygan Area School District. All interested persons shall make written application to the Assistant Superintendent of Human Resourcesby 4:00 p.m. on August 13, 2014. The Sheboygan Area School District does not discriminate on the basis of age, handicap, marital or parental status, national origin, pregnancy, race, religion, sex or sexual orientation.
Applications will be accepted only through the Wisconsin Education Career Access Network (WECAN). Go to: http://services.education.wisc.edu/wecan/pub/vList.cfm?inst=7342 to view the vacancy and to submit your application materials.
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|42 posts found
Novice Member
Joined: 12/24/05
i agree with Ms Jonte primarily because i have seen this same dysfunctional behavior in other areas of daily life.
someone always has some kind of drama, some kind of earth shattering or virtual world demolishing news and fears.
frankly, i think its because most people in our culture cannot seem to live without drama. they can't seem to live with the mundane world we inhabit. so they go to a virtual world. but in the end that virtual world becomes mundane in many aspects as well. so what then? well if you aren't being given the drama adrenaline rush you need you create it.
everyone was sure in politics that GWBush was the end of america, now its Obama. before them it was Clinton. every time things seem to be going well some group has to find what the secret drama is so they can then obsess unhealthily over it, get worked up on forums about it, and generally try to piss in everyone's pool in order to prove themselves right.
when you get older you suddenly realize that this is a rather large drain on what little energy you have left at the end of the day.
and when that happens you finally wave goodbye to the dramatis personae (except on occasion when you get really bored >.<).
basically, you get over the drama and you get over yourself and then the world doesn't have to be something exhausting.
"There are at least two kinds of games.
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Advanced Member
Joined: 5/06/10
I said this for the past few years MMO's are dieing, I have ran a community for 14 years, I see more players playing FPS games and most that leave because there isn't enough good games and because they like different types of games. Heck I went to school to get my degree to help game production and wanted to make MMO's and been involved with them. Well sadly publishers want fast cash and will ruin any good chance at a good game.
Now we have indies, some people on this site make rude remarks because some don't look as pretty, they want some thing different, some indies do that but gamers want it all and for nothing, not all gamers but alot say this, I read , blog and listen to all of this.
MMO's are dieing.
Reasons are, Old gamers tired of the games we see, to easy... We are used to UO, DOAC, AC1, and EQ, when MMO's were fun, now they just suck.
New gamers want it all and for free, I listen to this even in my community, and when I blog, OH Sub base!! Never mind, really??? I have to pay are you kidding me, well F2P ruins it, because bad communitys most of the time, and cheaters every where and gold sellers, so people leave.
To many games with this so called end game when people hit max level they quit, and then every person in there guild follows to the next MMO a month or two later, I see that alot in most communitys.
Iphone and ANdroid is where the DEVS with any brains are going , because one its faster to make, and cheaper to make. You can play these games anywhere and cheap.. Plus you can play a silly game for a few mins and don't have to worry about some jerk on the net calling you names and being annoying, sorry but this is true the market is going this way. These are facts, check for your self...
I love MMO's and would like to see better ones , but if people want stop and think, that a good one takes time and money and gamers need to stop throwing fits like a 3 year old maybe a good company would make one.
I personally think it can be an Indie if people would lay off with how dated they look when in fact, AC1 was bad looking but an amazing game, best game I have ever played hands down.
My wife nags me to make a Modern Asheron call . Just maybe one day.
Advanced Member
Joined: 5/06/10
Originally posted by NinjaGaz
So you know many Indies have tried this, but people see full loot and don't want to play it, I have seen games take out full loot with insurance, and people still hate PVP..
The issue is you have people who love that style of combat were others hate it, some love hosuing, some hate it, there is no happy medium today, so that is the hard part.
I hate questing in most MMO's today to much hand holding, I perfer lore base like AC1, sadly we don't have this, if we did people would freak, heck even Secret World tried something like that and look how many what I call new gamers whined and said it was to hard, so I think todays gamers ruin it and make it so hard for devs to make games.
I have blogged and asked gamers what is the perfect game for them combat style,Game play Mechanics, housing or not, PVP or not etc. I get the dumbest comments.
I get make a good game, well what is a good game to you!!! Most people can't answer this because as the poster above me said I think people like to cry about what ever they can, because they can.. They aren't happy unless they can complain, I see this alot as well, I been playing MMO's since the very first one was made...
Hard Core Member
Joined: 7/19/11
It is silly to say that X will kill the genre, but it's certainly the truth that casualization has killed it for me. Over the years, the things I enjoyed were cut out and replaced with convenience features like AHs, teleportation to instances or cities, instances themselves, no meaningful penalties for failure, less of a chance of failure and many others. It all piled up and now i barely even register when a new mmo is announced/hyped up. I wouldn't say it's casual players but rather developers who feel they must cater to this crowd.
Made History
Joined: 7/11/11
Pink, it's like red but not quite.
Originally posted by RudedawgCDN
And the next genre is overdue and likely to arrive any moment now. (And if LoL is the first baby of the next gen, it already has.)
"My ancient favorite will still be around a decade from now, but I won't be playing it because I'll be doing [xxxx] instead..."
Old Blues Fans muttering about the emergence of Elvis...
Self-pity imprisons us in the walls of our own self-absorption. The whole world shrinks down to the size of our problem, and the more we dwell on it, the smaller we are and the larger the problem seems to grow.
Hard Core Member
Joined: 10/10/03
The genre has already died a couple of times, the end was nigh years ago. MMOs today are different games but are still using the same genre title. They are likely to change even more over the next few years so if you like them the way they are now, play them while you can.
Apprentice Member
Joined: 11/22/05
As long as it's alive for me, I don't care if it's dead for you.
Advanced Member
Joined: 6/27/11
From the Article....
"The emergence of movies in the 1920s didn't kill live theater. More people buying radios in the 1930s didn't kill off the movie industry, nor did more people buying televisions in the 1950s. The invention of the computer and the emergence of the Internet hasn't killed any of the entertainment mediums that came before it. Moreover, all of those things has, in decades of Cassandra-like hand wringing, been proclaimed again and again as the imminent killer of the written word. You tell me, how's the publishing industry doing? Are people still reading? You bet they are, and in more convenient and inventive ways than ever."
And these events also changed each of these genres, these things, forever. They were never the same again.
It's not that the MMO Genre will die.... No it will not die...
It is that the MMO Genre will change in ways we older fans do not want, or appreciate, or agree with. For many of us the MMO Genre HAS died... for us personally. I know several People in real life that used to play MMOs years ago, but they did not agree with the changes, or did not like the direction MMOs were going, so they quit. Good Players gone that helped make the genre special.
The MMO Genre is not, nor will ever be, just software and servers, or just Investors dumping their money into it, or great gameplay and graphics. It is all these things plus something much more important.....it's also the Players themselves that make the MMO genre what it is. Without the Players the genre is meaningless. Anything that affects the Players affects the genre.
That's why Changes to MMOs to attract different People than they did before feels like such a Personal Attack... because the business decision to change customer Bases by changing who is attracted to MMOs *IS* a Personal Attack.
That's why for some of us the MMO genre Sky has fallen.
Advanced Member
Joined: 6/27/11
Originally posted by DamonVile
I do care if it's dead for you.
I find it very troubling that you and others hold this attitude, this point of view. That is not a good indicator of the future of this genre OR our collective real life future either.
Advanced Member
Joined: 12/02/04
OP you seems missing the point and not understand what some saying here.
Offcorse when someone say mmo's are dead don't mean they are.
If millions like mmo's with spoonfed gameplay and cookies plus shops you can buy your way to top thats fine but for me and few others mmo's are DEAD.
Understand OP?
New players keep comming and more and more playing becouse of easy acces through all kinds of devices and gameportals you can play games and mmo's.
F2P is defenition of death to mmo's yes...but prolly not for millions who want meaningless spoonfed cash grabbing monsters comming into there lifes and grab there wallets or give them cookies without any sweat or achievement:p
If i shout mmo's are dead there dead for me its THE END prolly not for you OP and many others fine by me have fun.
For me yes:)
Back to solo games which are alive and kicking for me:)
Novice Member
Joined: 6/12/12
The MMO surface has barely been scratched yet. When you boil it all down, EQ 1 - Next, DAoC, WOW, WAR, Conan, GW2, LotR - they're all the same game. MMOs have barely begun. We're still in the infancy stage, and one baby started to walk and fell over.
The reality of millions of humans connected via computers is the ultimate gaming environment. We've only just begun...
Novice Member
Joined: 6/12/12
"not everything on offer will be Tolstoy. Sometimes it'll be Twilight."
It's more like editing the writing in "War and Peace" to appeal to fans of "Twilight". Not only that, but getting rid of all the unedited versions. I know that analogy overstates the difference but I'm not worried that there'll be no games called MMOs in the future. I'm worried that none of them will be things I want to play.
Hard Core Member
Joined: 10/10/03
Originally posted by iridescence
This is close to by main concern, if there is only meaningless crap to consume you are never going to realise that there could be something else. Those who never saw what we had before will assume you can only make MMOs this way. Not that I have a blinkered view of the past, some things about the old gameplay are better left in the past. As gamers have now been replaced by social media types as the market to go for I can see no way that players will end up addressing these issues. At least the solo players were gamers, they had a gaming ethos even if it was not the same as ours.
We are moving into an era where gaming is going to be driven by the preferences of those who only game as an occasional pastime. I doubt it is going to be a bright future.
Hard Core Member
Joined: 10/02/12
The problem with MMOs these days, in my opinion, is that developers are just making the game, and forgetting to make a world. In all the MMOs that most people seem to love, they felt immersed in a world, small things like npc chatter, day/night cycles, large zones to explore, etc... All of this created an experience that no other genre could provide.
Nowadays it feels like we are all playing a lobby game waiting on our pvp/instance queue to pop whilst running circles in a player hub. I truly believe that if just one developer can go back to creating a world to play in, and not just a game to be put down after the first month, people would flock to it.
Novice Member
Joined: 6/14/12
Changes to MMOs kill entertainment about as much as articles like this kill MMO forums.
The emergence of this website, for example, did not deter other game-themed websites from forming.
My analogy is more on-topic than you'd think.
There are game websites (other than MMORPG.com) that scour the web for video game topics, and put those topics on their website solely to generate hits. They carefully wrap their meta data with proper search tags to ensure their websites show up while browsing gaming topics, but they don't offer anything that isn't available somewhere else.
Similarly, there are video games that scour the pre-existing video game world for content, and put that content in their games solely to generate interest. They carefully craft their games' hype & advertising effort with keywords like Innovative and Unprecedented, but don't offer any gameplay that isn't available anywhere else.
The biggest change to the gaming landscape is virtual reality. The nonsense we argue about today will be fodder for tomorrow's "old school gamer" arguments.
Bitter Vet™
Joined: 9/13/06
Fools find no pleasure in understanding, but delight in airing their own opinions. Pvbs 18:2, NIV
Originally posted by Scot
I agree, but think we've been in this mode for a number of years now, but the future still has a few bright spots on the horizon.
In my day MMORPG's were so hard we fought our way through dungeons in the snow, uphill both ways.
Bitter Vet™
Joined: 9/13/06
Fools find no pleasure in understanding, but delight in airing their own opinions. Pvbs 18:2, NIV
Originally posted by 9reesracer9
OK, let's talk about the entertainment/TV analogy.
Say my favorite form of movie back in the day was "the Western".
Now, when movies/TV were young, you could find westerns all over the place, much like early MMORPG's and their more realistic virtual worlds.
But as time moved on, entertainment changed, and you would be hard pressed to find more than 1 or 2 western themed shows/movies in any given year. If I really want to enjoy a lot of westerns, my only option is to back and watch all the old titles and shows, because there's no real modern option.
The MMORPG industry is a lot like this. More entertainment than ever before, but if I really want to play a MMORPG designed the way I like them, I have to go back and play a DAOC free shard set to 2003. (which I've been doing the past 5 or 6 months now)
No, the industry isn't dead, but MMORPG's with the game designs I favor died a long time ago, and yes, it actually was the entry of the more casual gamer into the marketplace that killed them off.
Your not being paranoid if someone really is out to get you.
In my day MMORPG's were so hard we fought our way through dungeons in the snow, uphill both ways.
Hard Core Member
Joined: 6/28/12
Good article!
Our hobby is changing to be sure. More people are playing games than when I started to. I like the mall analogy. When shopping malls started appearing across america and more recently in Europe, people said it was the end of downtowns. To a certain extent, this was true. The traditional downtown stores died but more recently they have begun to flourish as merchants learned to deliver a differentiated shopping experience. Also many failed to realize the malls attracted traffic that other merchants could advantage if they knew how to attract it; e,g did Wow attract more people to the genre. sure it did. Does one need to develop a new "Wow." Absolutely not.. You need something different..
Developers need to build a better experience. They need to learn about what works and what doesn't and apply what is learned. What does that look like? I'm not sure. I don't develop games for a living but if I did here's a few things that I would include:
Why am I excited about ESO? See the list above.. They seem to be on it...
Made History
Joined: 7/11/11
Pink, it's like red but not quite.
Originally posted by Kyleran
Shrug. The number of TV viewers who would prefer Westerns so strongly that nothing else could entice them to turn on their TV is so vanishingly small, TV producers will happily write them off and just move on.
You can rope them in with the once-a-decade primetime reunion special, at least while a couple of the cast members are still alive. (Gunsmoke did theirs in '78)
Self-pity imprisons us in the walls of our own self-absorption. The whole world shrinks down to the size of our problem, and the more we dwell on it, the smaller we are and the larger the problem seems to grow.
Novice Member
Joined: 10/11/11
As a player of WoW, Eq1/2, Lotrs, SWToR, Vanguard, Tera, and previous player of FF11/SWG/DDO/STO, as well as betas of FF14ARR/Rift/STO, I can attest that the genre has gotten extremely stale. We don't even get anything exciting for game content updates anymore~
You wait and wait, and then that anticipated update finally arrives, and its boring, some tiny little isle like WoW's timeless isle, or more raid content!! Whooo....
Well, it isn't like they are to poor and incapable of giving us more, companies just won't give us more. We all love more tradeskill crafting recipes to have fun with, we all love more random fluff like world events, and silly little things or even accept copy/paste geography layouts with copy/pasted npcs. It doesn't all have to be new artwork, it just has to be new dialogue and different quests!
Games come out with cool new features like WoW's scenarios, then abandon them as they make the gear outdated and worthless with Timeless Isle's easier to attain alt loot and new lfrs/raids for better gear! Release some awesome dungeons originally with an expansion, but then never bother to provide harder challenging ones with current equipment standards. Trivialize outdate all previous expansion content with every single game update patch release, so that all of the players move on to the "best shiny new thing" .
Now, we have the technology that we could combine WoW's flexible raids with Lord of the Rings Online skirmish 1,3, or full party system, with Everquest 2's scaling level content. We even have phasing on WoW to up population in zones, however what is the point of killing a world boss when the mounts are non-existant 1% or .025% drop rate, and the gear just got outdated by that brand new content update patch?
Everyone can't always rush off to the new expansion and leave the older ones deserted and empty ghost towns, that is what kills mmos right now. Only the current expansion is "relevant". Only the newest content update is desired.
My boyfriend quit playing mmos because they are all the same stale, however I remain and will always continue to do so (especially since most games are free).


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TUCSON, ARIZ. (Jan. 26) - The New Mexico State men's tennis team suffered its first loss of the season to University of Arizona 4-2 on Saturday afternoon after poor weather delayed the match in Tucson, Ariz. The Aggies now move to 2-1 on the season.
Due to inclement weather, the doubles matches did not take place, as there was rain that washed out the three matches. However, once the storm cleared, the teams took to the court for singles play where the Aggies fell at the No. 2, 4, 5 and 6 spots.
"Once we got going after the rain, I thought the team played well," head coach Carlos Vargas said. "This was a tough match and we knew that going into today. It was good preparation for what we have coming up the rest of the season."
Louis Ramirez led things off for the Aggies at the top spot. The lone senior claimed a 6-3, 6-1 victory against Wildcat Andre Vidaller. Daniel Fernandez picked up the other Aggie point at the third position, 6-0, 6-2. The Wildcats took the point on each of the other four courts in straight sets.
The Aggies now continue on the road as they head to Las Vegas, Nev., to meet UC Riverside, host UNLV and Southern Miss in three days of competition.


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Psychologist - but sometimes i'm conjured with Ouiji boards and say hello!!. I'm a Chocoholic ghost living in hell and i can be your worst nightmare....
I am who I am. I like what I like. I love what I love. I do what I want. Get off my back and deal with it. It's my life, not yours!.
I don't mind who you are or what kind of a person you are if it be goth, emo, rocker, trendie, gay, straight or bi!, if your a nice person, then thats all that matters.
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Honestly, i'm an Angel..... The horns are just to keep my "Halo" up straight.
ask me XD
I have always had a heart towards animals. When I feel down they bring me up. Knowing when someone says something to me that scars me for life I know all I have to do is hug my animals. Paul McCartney is my hero. I have liked him since the beginning of fourth grade. When he was a vegetarian I looked him up and I came to Peta. I am addicted to animals, Paul McCartney, and Peta2. I am a huge fan of One Direction. I'm a vegetarian and I love lions and SEALS! Add me!
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Rumors of the death of Sony's PS4 controller thumbsticks are—hopefully—greatly exaggerated.
I know I've said we should abandon all this next-gen rumor-mongering, but I simply must comment on this latest bit of possible information on the redesigned PS4 "SplitShock" controller, even if it is all rumor and speculation stemming from questionable sources that are likely just trying to punk news outlets.
We've heard already that the controller will likely have touch support, either on the front or rear (or both) of the controller, leading to some of the buttons being moved around a bit. Apparently the controller will look and feel rather similar to the DualShock, but will have other changes as well.
Now VGRevolution is reporting that the PS4 controller may abandon thumbsticks altogether in favor of those rumored front-facing touch pads, if their source (apparently an ad
PR agency) is accurate.
From the item sent to VGRevolution:
The first and most immediate change when a consumer looks at the SplitShock is the removal of the analogue sticks and the inclusion of touchpads in their place. The touchpads serve the same function as the analogue sticks.
When a consumer is not playing a game, the SplitShock touchpads function as a track pad with both halves making a larger area to swipe and select items. The touchpads are also fully programmable by developers. This gives them the freedom to use the touchpads as they see fit. For example, if the game doesn't require analogue controls, the touchpads can be used as an alternate input device. This allows games ported from IOS or Android the ability to retain their original control scheme.
Meanwhile, it would render PS4 games almost as useless as the vast majority of touch-based mobile games out there.
This would be an abomination of the highest order. If Sony goes this route, they're making a huge, unforgivable mistake.
I don't care how well the touch pads work; the thing that makes even the Vita itself an attractive piece of hardware are the thumbsticks. You simply cannot achieve the same level of accuracy with touch that you can with a pair of thumbsticks. The shooter genre would die a grizzly death on PS4 if this is true; action-combat games like Demon's Souls would also be woefully hard to play.
The lack of dual thumbsticks is why I'm irritated to no end trying to play games with the Wii nunchuck set-up (or, rather, one reason the Wii controllers irritate me so much.)
A PlayStation controller with no thumbsticks? That's like a sandwich without bread, or beer without alcohol.
I hope—and suspect—this is a bad prank. If Sony is at all serious about catering to the so-called "hardcore" gaming crowd, they'd be courting disaster with such a bizarre design decision. I've reached out to Sony to see if they can comment, but I wouldn't expect anything solid at all until the 20th (if then.)
P.S. I'm intentionally invoking Betteridge's Law with this post's headline.
P.P.S. Some people have asked why I'm "reporting" on such an obviously fake "story." So to be absolutely clear: sometimes these prank stories are frightening reflections of real business decisions made by big companies in the gaming and tech world. For instance, motion controllers were taken very seriously for some time, even though there's no way any of them are anywhere as accurate or as fun to use as a traditional controller. Likewise, touch-screen gaming and various other trends are constantly taking the industry by storm. So is this a ludicrous and almost certainly fake story? Yes indeed. Is it worth pointing out why this would be a terrible idea? I think so. Truth can be stranger than fiction, after all. And sometimes it's just fun to post a little rant….


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True Crime spree hitting Hong Kong in Q4 2010
[UPDATE] Activision brings back open-world action series in Chinese metropolis; ModNation Racers studio United Front Games at the wheel; PS3, 360 now confirmed.
[UPDATE] Activision brings back open-world action series in Chinese metropolis; ModNation Racers studio United Front Games at the wheel; PS3, 360 now confirmed.
Rapper's insistence on game console contributes to tardiness at New York charity event.
Latest update pushes number of backward-compatible games past 250; 39 games added to list, nine games receive updated support.
Popular Xbox titles to sell for $9.99; Microsoft confirms 16 participating games in program's "first wave."
The expanded, non-console version of Activision's action game has arrived in stores.
First non-console version of the popular driving-shooting-fighting game arrives at the factory.
The PC version of Activision's driving/fighting/shooting game is nearly finished, and we get a final chance to check it out in development.
Activision's upcoming crime action game for the PC will feature several exclusive character skins. Producer Brian Clarke takes us behind the scenes.
Activision's successful console crime drama is coming to the PC, with PC-only features like multiplay and an even better soundtrack.
Activision confirms a PC version of its best-seller is in the works.
This guide to True Crime Streets of LA includes walkthroughs for every mission, including alternate missions and episodes, as well as cheats, and advice for picking out upgrades.
Declining television ratings are prompting advertisers to reach the coveted young male demographic through games.
Jeff Gerstmann delivers the final word on True Crime: Streets of LA.
Activision confirms West Coast rapper will be playable in its upcoming Streets of LA
We try out Activision's upcoming Los Angeles-based action game.
Cell phone versions of two upcoming Activision games planned.
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