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Year of publication
- 2012 (4) (remove)
- Biofuel (1)
- Butanol (1)
- Ehrlich pathway (1)
- Fermentation (1)
- Genetic engineering (1)
- Isobutanol (1)
- Saccharomyces (1)
- Valine biosynthesis (1)
- Yeast (1)
- bioethanol (1)
- Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae (2012)
- Background: In mixed sugar fermentations with recombinant Saccharomyces cerevisiae strains able to ferment D-xylose and L-arabinose the pentose sugars are normally only utilized after depletion of D-glucose. This has been attributed to competitive inhibition of pentose uptake by D-glucose as pentose sugars are taken up into yeast cells by individual members of the yeast hexose transporter family. We wanted to investigate whether D-glucose inhibits pentose utilization only by blocking its uptake or also by interfering with its further metabolism. Results: To distinguish between inhibitory effects of D-glucose on pentose uptake and pentose catabolism, maltose was used as an alternative carbon source in maltose-pentose co-consumption experiments. Maltose is taken up by a specific maltose transport system and hydrolyzed only intracellularly into two D-glucose molecules. Pentose consumption decreased by about 20 - 30% during the simultaneous utilization of maltose indicating that hexose catabolism can impede pentose utilization. To test whether intracellular D-glucose might impair pentose utilization, hexo-/glucokinase deletion mutants were constructed. Those mutants are known to accumulate intracellular D-glucose when incubated with maltose. However, pentose utilization was not effected in the presence of maltose. Addition of increasing concentrations of D-glucose to the hexo-/glucokinase mutants finally completely blocked D-xylose as well as L-arabinose consumption, indicating a pronounced inhibitory effect of D-glucose on pentose uptake. Nevertheless, constitutive overexpression of pentose-transporting hexose transporters like Hxt7 and Gal2 could improve pentose consumption in the presence of D-glucose. Conclusion: Our results confirm that D-glucose impairs the simultaneous utilization of pentoses mainly due to inhibition of pentose uptake. Whereas intracellular D-glucose does not seem to have an inhibitory effect on pentose utilization, further catabolism of D-glucose can also impede pentose utilization. Nevertheless, the results suggest that co-fermentation of pentoses in the presence of D-glucose can significantly be improved by the overexpression of pentose transporters, especially if they are not inhibited by D-glucose.
- Novel strategies to improve co-fermentation of pentoses with D-glucose by recombinant yeast strains in lignocellulosic hydrolysates (2012)
- Economically feasible production of second-generation biofuels requires efficient co-fermentation of pentose and hexose sugars in lignocellulosic hydrolysates under very harsh conditions. Baker's yeast is an excellent, traditionally used ethanol producer but is naturally not able to utilize pentoses. This is due to the lack of pentose-specific transporter proteins and enzymatic reactions. Thus, natural yeast strains must be modified by genetic engineering. Although the construction of various recombinant yeast strains able to ferment pentose sugars has been described during the last two decades, their rates of pentose utilization is still significantly lower than D-glucose fermentation. Moreover, pentoses are only fermented after D-glucose is exhausted, resulting in an uneconomical increase in the fermentation time. In this addendum, we discuss novel approaches to improve utilization of pentoses by development of specific transporters and substrate channeling in enzyme cascades. Addendum to: T Subtil, E Boles. Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae. Biotechnol Biofuels 2012; 5: 14 PMID: 22424089 DOI: 10.1186/1754-6834-5-14
- Amino acid transporter genes are essential for FLO11-dependent and FLO11-independent biofilm formation and invasive growth in saccharomyces cerevisiae (2012)
- Amino acids can induce yeast cell adhesion but how amino acids are sensed and signal the modulation of the FLO adhesion genes is not clear. We discovered that the budding yeast Saccharomyces cerevisiae CEN.PK evolved invasive growth ability under prolonged nitrogen limitation. Such invasive mutants were used to identify amino acid transporters as regulators of FLO11 and invasive growth. One invasive mutant had elevated levels of FLO11 mRNA and a Q320STOP mutation in the SFL1 gene that encodes a protein kinase A pathway regulated repressor of FLO11. Glutamine-transporter genes DIP5 and GNP1 were essential for FLO11 expression, invasive growth and biofilm formation in this mutant. Invasive growth relied on known regulators of FLO11 and the Ssy1-Ptr3-Ssy5 complex that controls DIP5 and GNP1, suggesting that Dip5 and Gnp1 operates downstream of the Ssy1-Ptr3-Ssy5 complex for regulation of FLO11 expression in a protein kinase A dependent manner. The role of Dip5 and Gnp1 appears to be conserved in the S. cerevisiae strain ∑1278b since the dip5 gnp1 ∑1278b mutant showed no invasive phenotype. Secondly, the amino acid transporter gene GAP1 was found to influence invasive growth through FLO11 as well as other FLO genes. Cells carrying a dominant loss-of-function PTR3647::CWNKNPLSSIN allele had increased transcription of the adhesion genes FLO1, 5, 9, 10, 11 and the amino acid transporter gene GAP1. Deletion of GAP1 caused loss of FLO11 expression and invasive growth. However, deletions of FLO11 and genes encoding components of the mitogen-activated protein kinase pathway or the protein kinase A pathway were not sufficient to abolish invasive growth, suggesting involvement of other FLO genes and alternative pathways. Increased intracellular amino acid pools in the PTR3647::CWNKNPLSSIN-containing strain opens the possibility that Gap1 regulates the FLO genes through alteration of the amino acid pool sizes.
- Cytosolic re-localization and optimization of valine synthesis and catabolism enables increased isobutanol production with the yeast Saccharomyces cerevisiae (2012)
- Background: The branched chain alcohol isobutanol exhibits superior physicochemical properties as an alternative biofuel. The yeast Saccharomyces cerevisiae naturally produces low amounts of isobutanol as a by-product during fermentations, resulting from the catabolism of valine. As S. cerevisiae is widely used in industrial applications and can easily be modified by genetic engineering, this microorganism is a promising host for the fermentative production of higher amounts of isobutanol. Results: Isobutanol production could be improved by re-locating the valine biosynthesis enzymes Ilv2, Ilv5 and Ilv3 from the mitochondrial matrix into the cytosol. To prevent the import of the three enzymes into yeast mitochondria, N-terminally shortened Ilv2, Ilv5 and Ilv3 versions were constructed lacking their mitochondrial targeting sequences. SDS-PAGE and immunofluorescence analyses confirmed expression and re-localization of the truncated enzymes. Growth tests or enzyme assays confirmed enzymatic activities. Isobutanol production was only increased in the absence of valine and the simultaneous blockage of the mitochondrial valine synthesis pathway. Isobutanol production could be even more enhanced after adapting the codon usage of the truncated valine biosynthesis genes to the codon usage of highly expressed glycolytic genes. Finally, a suitable ketoisovalerate decarboxylase, Aro10, and alcohol dehydrogenase, Adh2, were selected and overexpressed. The highest isobutanol titer was 0.63 g/L at a yield of nearly 15 mg per g glucose. Conclusion: A cytosolic isobutanol production pathway was successfully established in yeast by re-localization and optimization of mitochondrial valine synthesis enzymes together with overexpression of Aro10 decarboxylase and Adh2 alcohol dehydrogenase. Driving forces were generated by blocking competition with the mitochondrial valine pathway and by omitting valine from the fermentation medium. Additional deletion of pyruvate decarboxylase genes and engineering of co-factor imbalances should lead to even higher isobutanol production.


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(SportsNetwork.com) - New York Giants running back David Wilson will miss the 2014 season due to a neck injury and his career could be over, according to multiple reports.
Wilson left practice last Tuesday with a burner and was sent to a hospital for tests on his surgically repaired neck. He sat out the remainder of last week's practices and Sunday night's preseason game.
Wilson, 23, announced July 21 that he was cleared to practice after undergoing neck surgery in January to fuse vertebrae and repair a herniated disk. The former first-round pick was hurt in a Week 5 loss to Philadelphia last season.
On Monday morning Wilson met with spine specialist Dr. Frank Cammisa, who performed the surgery on Wilson in January and it was determined that Wilson should not play this season, according to the reports.
In two seasons with the Giants, Wilson has rushed for 504 yards and five touchdowns over 21 games -- including six starts. The Virginia Tech product has also caught six passes for 42 yards and a score.
The Giants will rely on veteran free-agent acquisition Rashad Jennings and rookie Andre Williams if Wilson can't play.

subset: commoncrawl


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Oct 8 2009
Child Sponsorship: Life After Graduation
Tulancingo is located in a semidesert valley in central México. The view is beautiful and green with big cactus trees standing on the horizon.
The area of Tulancingo holds great history from the ancient Toltec and Otomi cultures. Although the inhabitants are mostly dedicated to farming and agriculture, a few other industries are also in…


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Kristen flies off the handle after speaking to Dr. Chyka, Eric's taken to the hospital, and Nick and Gabi discuss their marriage.
Nicole tends to a feverish Eric in his room in the capital. He comes around and Nicole can't find her cell phone so runs to the concierge to call a doctor. Still in disguise, Kristen's stopped in the lobby by George and a police officer. George points out she didn't pay when she checked in. They assume she's a hooker. The cop prepares to arrest her but Martha walks up and explains this is all a misunderstanding. She forgot to file the paperwork when 'Miss Taylor' registered. Kristen leaves and Nicole rushes out with the news of Eric's collapse. George cringes, knowing they'll have to wait 8 hours just to see a physician at the hospital.
Abby backs away when Chad moves in for a kiss at the cafe. He admits when he asked to 'ride the wild tiger' tonight, he didn't want it to be as friends. He can't get her out of his head and won't give her up without a fight. She claims she didn't see it coming. They discuss hiding the incriminating video of Sami jumping on Bernardi. Chad approves of her morals. She thinks this is about sex but it's not. Still, he finds it special that she wants to save herself for the right guy though he isn't sure that's him.
Arianna bawls at Sonny, Will, and Gabi's apartment. Nick shows up with a mobile for the baby. Sonny thanks Nick and installs it. It works - the baby stops crying. Will accepts another apology from Nick, who thinks Arianna is going to have 'one hell of a father'. Gabi and Nick head out to discuss their marriage while Sonny takes the opportunity to sneak in a kiss with Will. Chad arrives and opens up about what's been going on between him and Abby. What if Cameron's not the right guy for her?
Jenn turns up on Daniel's doorstep to make amends. Talk is overrated, so they start making out. Daniel snaps out of his fantasy. He bumps into Jennifer at work and she shows him the love note he dropped for her. She asks him to trust her to handle her son in her own way but Daniel thinks she has blinders on where JJ's concerned.
Marlena stops by the rectory. She's told Eric already left for the capital.
Marlena arrives at the hospital and interrupts Daniel and Jenn's argument about JJ with talk of work. A call from Nicole interrupts. She tells Dan she's with Eric, on her way in an ambulance to Salem. They arrive moments later. Eric's temperature has soared to 105. Daniel takes him into the ER and examines him. Roman turns up and he and Marlena grow sick with worry. Marlena confronts Nicole, who explains why she went to the capitol in the first place. In Eric's room, Daniel isn't sure if what Eric has is a virus or not since his white blood count is fine. Later, Eric is doing much better but Daniel admits to Nicole if he didn't know better, he'd think Eric was poisoned.
At home, Jennifer ruminates over her argument with Daniel about her son. Abby arrives and calls herself a screw up. She admits she told Cameron she was ready for sex but she's not. She talks about how much fun she had with Chad at "Whoopie World" but Jennifer orders her to stay away from him. Besides, isn't she into Cameron? Abby's unsure of her feelings considering she can't stop thinking about Chad.
Gabi and Nick walk through the square. Things are strained while they discuss his firing. Gabi suggests he go to Sami for work. They rehash the past and Nick says he does care for her. When he asks to be friends, Gabi shakes her head. She cares about him and wants him to get help but she needs to focus on Ari and her brother once he wakes up. She doesn't want to do anything else that may screw that up. Nick tears up. He thinks her decision to move in with Sonny and Will was a good one. They part ways.
Kristen returns to the DiMera mansion and starts watching the video footage of sex with Eric when Dr. Chyka arrives. He tells Kristen the properties of the drug weren't as potent and Eric could remember everything. Kristen swears and throws her drink at him.
Gabi returns home and interrupts Will and Sonny who are close to having sex. She heads for a nap and Will goes to sing to Arianna to help her sleep.
Salem Spoilers for the next Days Of Our Lives:
Eric wakes up and tries to recall what happened.
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Magellan RoadMate for iPhone updated, want a promo code? [give away]
Magellan RoadMate for iPhone has just been updated to version 1.3 and that means a it's received several new features to help you better and more enjoyably navigate from point A to point B:
- Location-based offers and coupons – First branded GPS App to provide relevant offers on-screen while you route to your destination. Users can re-route to the sponsoring store's location or save promotional coupons for redemption at a later time.
- iOS 4.0 support – Multitasking capabilities enable navigation with turn-by-turn instructions and continuous routing to run in the background while using other applications.
- LifeTime real-time traffic information – Included free in the version 1.3 update, users can avoid traffic congestion by comparing current and proposed alternative routes, making well-informed decisions ahead of traffic delays.
- Sharing points of interest – Users can easily share destinations and POIs via email using the RoadMate app.
To celebrate the update Magellan RoadMate is currently on sale in the iTunes App Store: Magellan RoadMate North America is available for $44.99 (regularly $59.99); Magellan RoadMate USA is $34.99 (regularly $49.99); and Magellan RoadMate Canada is $29.99 (regularly $34.99
They've also given us three (3) promo codes to pass on to you, our awesome readers. Details and screen shots after the break!
To enter the give-away just leave a comment in the thread below telling us which of the new features you like best. Make sure to leave a real email address (it won't be public but we'll need it to contact you if you win). As always, promo codes only work in the US App Store (Apple's rule, not ours!)
[gallery link="file" columns="2"]
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Senior Editor at iMore and a practicing therapist specializing in stress and anxiety. She speaks everywhere from conferences to corporations, co-host of Vector, Review, and Isometric podcasts, and should be followed on Twitter @Georgia_Dow.
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Reader comments
Magellan RoadMate for iPhone updated, want a promo code? [give away]
Sharing points of intrest
I like best the idea of location-based offers and coupons. What a great concept!
The traffic updates are an awesome feature! Would love to win this!
I like that I will less likely get lost in a paperbag again. And the location based coupons. Hope this works in multitasking
iOS 4 Support is my favorite new feature by far. Being able to use this as an all-in-one navigation system, listening to Pandora in the background over your car stereo while Magellan Roadmate occasionally pops in to give you turn-by-turn directions... that is the life!
Live trafic updates is awesome!!!!
Location based coupons is a great new feature. I wish a lot more apps would take advantage of smartphone coupons
Coupons sounds good, but I think the email sharing of destinations is the best new feature overall! Love to get this app to compare to Navigon and MotionX!
Real-time traffic updates sound great!!
Got to love the location based coupons, what a great way for businesses to drum up business.
Love the lifetime real time traffic
A life-time of traffic updates is the best new feature. There is nothing more aggravating than being stuck in traffic you could have avoided if you had known in advance. Would love to win one of the promo codes. Keep up the good work TiPB.
Magellan RoadMate for iphone is the hands down #1 navigation app.
I would love to try it out as I have CoPilot, and it is the worst nav app available.
Points of interest (:
I like the traffic information the most. I have to check a separate app now, so it would be convenient to have all of that in one app. The email function and the coupons are also interesting features.
Would love the traffic updates.
Multi-tasking. A GPS app on the iPhone is nearly useless without that capability.
Traffic information is the best!
I like that they added iOS 4.0 support; no more worries about a phone call disrupting my directions.
The two features I like the best are:
1.) Multitasking- I like being able to play music while I'm navigating with the app.
2.) I frequently search for places to eat while I'm navigation. Coupons would come in handy to possibly get some discounts during my travels.
Looks like a solid app!
Location based coupons is a very valuable feature for the consumer. I love that concept.
Without a doubt the 4.0 OS update for multi-tasking! Why? Because as nice as local coupons might be...I doubt the support / list will be big enough at first to make a difference..maybe years from now more will jump on board now that Facebook is doing that (not the first, but the biggest name to get into that market). Multitasking is what it's all about. :)
I like the coupons, also the traffic report feature could be a life saver after or before work.
Man I would love a promo code for this great looking App.
Especially since my GPS was just stolen from my car last week.
This App looks to run circles around that old beast.
Looking forward to my next trip :-)
Traffic updates in the D.C. would be a bit of heaven ;)
Best thing I like: free traffic.
The multitasking feature looks to be the best feature in my book. Having the ability to run the background would be great.
I kinda like the coupon feature of this app. Pick me pick me pick me
Live update is most important to me given that I need navigation to get from gig to gig!
Location-based offers and coupons IS AWESOME. That'd be so useful when you're on a road trip.
Traffic updates for free rocks...
I think the location based offers are a really cool idea and hopefully they are implemented as slickly, not being a distraction what what is the primary goal of the application.
Lifetime traffic updates seem good to me!
Sharing points of interest would be something I would use since i like social networks and iOS 4.0 support sounds great
Like the Traffic Updates
Location based offers and coupons. Just think u stop at chipotle and there was a coupon for a buy one get one free. :-D
Pick me! I need this app! I have Navigon, but this looks possibly better.
Sharing POI's will be great!
Definitely needed is the ALTERNATIVE ROUTES, to avoid the traffic...
Love the LifeTime real-time traffic information - save time.
I like the "LifeTime real-time traffic information" feature the best because it would become really useful on my way to work. I would never have to renew the subscription for it, unlike other navigation apps.
Avoiding traffic, Alternate routs, time saved priceless
I liked "LifeTime real-time traffic information"! :D
I like the lifetime real time traffic being included. At&t says theirs is better because of the traffic updates so the moment fee is worth it. This proves them wrong!
By far the coupons would be the coolest. While on road trips I would love to know that I could save money on lunch by using the in app routing to specials.
Lifetime traffic!
I like the iOS 4 support (multitasking)!
LifeTime real-time traffic information
iOS4 support and multitasking of course.
The real time traffic will be helpful in Atlanta. Looking forward to that feature
Sharing points of intrest
Definitely the multitasking support. It would be nice always having it running in the background in the car when you wanted to use other apps.
Definitely, multitasking is a much needed feature.
iOS 4 compatability would be the best new feature for me, listening to pandora and being navigated in my car would be awesome!!
Real time traffic!!!! Another update today 1.3.1!! Keep them coming!!
The live traffic info is crucial and a welcome addition to what has been one of the navigation leaders for me. Thanks, Magellan!
I'm liking the coupon and location based feature. Could be a useful tool in saving so that I can spend more on the kids for the holidays.
I like "instructions and continuous routing to run in the background while using other applications."
YES! Why is it so hard to understand the desirability of this feature?
I have been a (stand alone) TomTom user for over two years (even updated my hardware), but it's still crashing a great deal out of the blue AND it's one more unit to carry on the two week drive I am taking to visit my son for the Holidays. I could really use software other than TomTom that just works even if I am making/taking a phone call.
Thank you for your consideration,
Traffic Updates, HANDS DOWN the best feature added.
I like that real time traffic updates are included!
I like the traffic report. Would come in handy for me.
LifeTime real-time traffic information! That's fantastic!
Real live traffic that very nice A++++
The real time traffic is a sweet feature! Looks impressive!
traffic information is the best feature i like... especially the fact that it's free!
Hot spots and points of interest please
Coupons and offers - would make it easy to know where/when to pull off the interstate and which hotel to choose!
Free lifetime real time traffic of course!
Multi-tasking definitely. Once you get used to it you can't go back.
Live traffic is nice. Multitasking would be a nice add on.
The traffic information is great, but the killer feature here is the multitasking.
I would love all new features! I'm directionally challenged! Seriously I would love a good GPS app. Maybe I wouldn't be afraid to venture out to new places. Thanks for the opportunity!
Definitely the iOS4 multitasking, that's my favorite. Live realtime traffic would be a close second. Pick me!
Life time traffic updates would be awesome, plus the nice multi-tasking!
Definitely the shared points of interest! Can't wait to put that to use with my family.
Really interested in the multitasking and the ability for the program to continually run in the background.
The multitasking function is awesome
For me, being a courier, the best two are the multitasking support and the real time traffic. Those are absolutely huge for me. I've been wanting to try this app, so come on give me the chance!
Free traffic updates/rerouting
I Love the new ios 4.0 support! Thank goodness for the multitasking.
I love the inclusion of location based deals. As a poor college student, finding ways to save money is always a good thing. With Magellan, it would really help me find the cheapest places to find food!
real-time traffic!
Free real-time traffic information. You have to pay for it on other GPS apps. Coupons is cool add-on since I do like to save money.
I love the lifetime traffic updates! thats amazing. thats one thing that alot of gps programs lack, and we all hate traffic! lol this update looks awesome (as always Chad).
For me the best new feature is the traffic updates. No more getting stuck in traffic in an area I'm completely unfamiliar with! Way to you Magellan!
I like the premise of lifetime traffic...could've saved me a few hours just the other day. :)
It would be great to have real time traffic reports!
Multitasking is always key in my book, especially when phone calls or txt interrupt what your doing.
Traffic updates for life is the best feature!
iOS 4.0 support is a must-have.
Real time traffic!!
Traffic = #1
the lifetime life traffic option would be my fav feature to get around rushhour gridlock
I'm definitely thinking multi-tasking, it would be a great addition.
I love the free for life traffic updates! Probably the best, since all other decent apps that cost $40+ make you pay per month! Best Nav app in the App Store!
Avoiding traffic snarls tops my list.
I don't have $40 for App so I don't know all the features but what I have read from your blog, I would say that ---> Location-based offers and coupons – First branded GPS App to provide relevant offers on-screen while you route to your destination. Users can re-route to the sponsoring store's location or save promotional coupons for redemption at a later time. Thats sick because if your diving and you want a bite to eat or coffee it will give u a coupon, hot awesome!
Really looking forward to the real-time traffic.
Multitasking!!! Points of interest also!
Definitely Real Time Traffic. Commute to work is a chore and this would obviously alleviate the stress.
I like the fact of location based coupons etc. from stores and re routing option to them. I do alot of driving for work and theres many times id like to stop for a coffee , gas, or a store or to and dont know where there located
Multitasking. I can do other stuff while navigating...but not while driving, of course!
Multi-tasking for the win!
I definitely like the real time traffic addition, very handy. I'd love to give it a try with a free promo code :)
Loving the real time traffic!!
Traffic. And of course ios4 support, or it wouldn't do me any good.
Lifetime traffic info for free is the bomb.
Or as Chad would say simply awesome,
Holy crap, the real time traffic update Is incredible! On my drive into Boston, I have radio traffic that is, at best, infrequent. An awesome updated app will finally let me decide if the Pike is worth it or I can chance 495. I want it please!
Having multi-tasking for a navigation app is absolutely critical.
Realtime traffic and the coupons sounds like great features
I like the life-time real-time traffic information and the multitasking.
Definitely the promotions. I would find this useful in my travel.
I like the location based coupon offers.
I love the traffic live updates, to avoid those pesky time wasting roads (not to mention the stress that comes from a 2 hour traffic jam).
No question coupons all the way!!!
LifeTime real-time traffic information!
The other two "big navigation apps" offer paid traffic only. And its only valid one-year at a time. That Magellen offers Free LifeTime Traffic is a huge plus over their competitors.
My favorite feature by far - Go Magellen!
Real time traffic def
Overall, the total package is well worth the purchase. However, I'm going to say that I love the coupons and promotions, so that when I see the traffic in real-time and know I don't want to drive, I can pull over for a a free cup of joe or other something else. Oh, the multi-tasking is nice, too!
Free lifetime traffic is the best feature for this update. It would help me alot in southern california for my commute to work. The traffic is horrible here.
I like the hot dog.
"Computer... where the hot dogs?"
Real time traffic for sure!
c'mon I need a new direction in my life hopefully Magellan will help
The lifetime traffic is killer. Always helpful to know when traffic is an issue to get where your going.
iOS 4.0 support – Multitasking capabilities
What the point without it.
My favorite feature is the sharing points of interest. That's awesome because with all the social networking going on, this is an obvious and great addition and will be I think the most used feature for the app, at least for me it will. Thanks TiPb!!!!
"Location-based offers and coupons " very cool idea.
I like real time traffic the best.
I like the real time traffic. It'll be good for getting around the city.
Real time traffic FTW!
Real time traffic definitely helps in LA traffic!!!
Reliable realtime traffic. Best feature on navigation systems ever.
Real time traffic. Coupons/ads not so much.
Live traffic
I really like the real-time traffic! That will make my commute dramatically smoother!
LifeTime traffic info., definitely, lifetime traffic info.
Although, being a fan of Yelp and UrbanSpoon, I like the shared POI, too!
Lice traffic
Real time traffic? For life!? That sounds awesome!
Real-time traffic is great to have. My regular route to work can get trafficky, so it's good to have suggestions on other routes.
Multi-tasking is the best!
Show me Realtime Traffic!
Real time traffic is a really nice feature!
Lifetime real-time traffic updates. Those are always helpful when driving around. (oh this app for free, too)
The real-time traffic is the most compelling feature for me. This looks like a good gps app and I hope i win!
The traffic feature for sure! Traffic is always a problem in Seattle, I think I need this app to steer clear of it!
LifeTime real-time traffic information sounds great to me.
Multitasking. Really needed for any nav app
coupons deals alright!!!!
Oh Georgia!! iOS 4 Multitasking support is the best!!!!
Owwwwwwwwwww!!!! Wolf call babe!!!!
real time traffic and multi feature sound like a winner
Real Time Traffic! If I can avoid the congestion, I will!
I would love to try this one for the real-time traffic information. Thanks tipb.com for doing this giveaway!
Real time traffic is going to be fantastic. Our old gps system quit on us. I would love to get this for my wife and I with the free promo please :D.
I like how it has free traffic, and not an add on subscription. Makes life easy! I'd love to try it out.
Real time traffic updates
Real-time traffic updates. In Philadelphia, especially with the bridges in and out of town on the East side -- that would be a godsend.
I'm liking that it has lifetime live traffic info!
Lifetime traffic!
I like the whole package. I'm driving all over the west coast for my job and have been using mapquest. Is good, but is missing features. Ie: total distance left & time left till destination.
The real traffic feature is pretty nice.
multitasking all the way!
Real time traffic, that's awesome!
I really like the new multitasking. Cool beans!!!!
Best feature - iOS 4 support, as this brings both a great nav PLUS the knowledge that multitasking is on the way.
Would love this app. The traffic info is key, especially in the traffic jam that is Atlanta.
I like the location based offers and coupons. What a great idea!!
Realtime traffic FTW
The real time traffic!! This can be very useful when going to work!!
Real time traffic! I travel all the time for work and avoiding congestion, especially in unfamiliar areas, would be fantastic!
The location based offers and coupons is a great feature and so is the Life time traffic reports. Overall it looks like a great app -- one that I'd be happy to win a promo code for :)
Multitasking and traffic!!
Of course the most useful feature will be the multitasking to make it a usable app.
Wow, I would love to try this one out!!
1) I love the new backgrounding feature. I can use this foe my daily commute! It'll help me be much more productive.
I'm liking the live traffic option!
Lifetime realtime traffic is great, but if I win this for free that is even better
I really like the coupon feature. Seems to go above what I get with Navigon there!
Gimme gimme gimme!!!! I would love to compare this to Navigon.
Real time traffic. Would be nice to know when and where to go when there is a traffic tieup!
I actually like the coupon feature too. Unique!
I dig the coupons! Only reason I use Foursquare. :)
I could sure use the Avoid Traffic feature here in Seattle.
I've been waiting for multitasking support. That has got to be my favorite new feature!
LifeTime real-time traffic is probably the best!!!
Real time traffic FTW!
Coupons is cool but has to be free live traffic. Awesome!
would be my first GPS app, interested to compare to Maps..
LifeTime real-time traffic.
If its good, its worth buying just for that.
Would love the coupon feature. I'm always looking for a deal!
Speaking of a deal. would LOVE to get a copy of Magellan RoadMate!!!
The real time traffic is the best one
i like the Multi-tasking and real-time traffic! Great Features!!!
Help an old man out
Real time traffic all I can say is yes yes yes!!!!!
Real time traffic sounds great!
Love that it's iOS 4 compatible.
Of the newly added features the traffic included for free is definitely the most useful! Other nav apps charge extra for such services which has led to me going back to the regular old Maps app for my day-to-day navigating and traffic check.
UI is much more compelling then my Tom Tom. Love real time traffic the best out of all the goodies.
Multitasking capabilities is what caught my attention.
Real-time traffic is awesome!
For me it has to be real time traffic!
I like the multitasking capabilities the best.
I really like the multi-tasking support.
Real time traffic does it for me.
I work with adults with developmental disabilities and using the gps to find a nearby starbucks offering coupons would give me the caffeine boost I need to get my morning going!!
Definitely the real time traffic!!!
The ability to share POI's will be great! Road trips in caravans and scavenger hunts in the future
Shared POI looks like the feature I would get the most out of.
Multitasking is a great new feature. This means now you can mount your iPhone in your car use your nav program, listen to the talk radio on your radio app and take phone calls all on one devise at the same time.
The Lifetime traffic update feature rocks!
Real time traffic for sure. I'm really hoping the Magellan app is solid, as I own three of the four big maps on-device players (Navigon, copilot, and Sygic aura) and all fall short in one way or another. Here's to hoping to win one that's worth it!
Coupons sounds awesome
Hoping to win a code. Look forward to the LifeTime real-time traffic information.
I like iOS 4 support. After all, everything is better with multitasking.
I really like the lifetime real traffic information. really helps to avoid traffic especially when there is an accident and unexpected congestion.
Un jeu super
Because of my roadrage issues, I would go with the real-time traffic
Real time traffic!
I actually am excited about the location coupons. Hope I get to try it out.
Lifetime real-time traffic
what could be more important than real-time traffic? Pointing you to the right direction is one thing, getting there on time is another. Thank you Magellan for updating your app.
Multitasking support is the best feature
movies, movies, movies, so i can program and drive it to the nearest theater. that's what i'm talkin about baby!
Multitasking is essential for iPhone GPS. would love to compare with navigon.
I like the real-time traffic
I would have to say real-time traffic update will serve me best. My pastoral duties require quick response to those in need. I can't afford to get stuck in traffic while my parishioner is in crisis.
I like the iOS 4 capabilities.
i like the location based coupon system. couldn't find any other gps that could locate local businesses so well.
I think the multitasking will be a huge improvement! There is a lot to love in this app. Hope I win!
Love the traffic info.
Obviously the multitasking is the big plus here.
Real time traffic , it gets pretty crazy here in Miami...
Multitasking is best
I love the real time traffic feature Its free tired of the crappy google map app which needs an update for route alternatives on traffic this app will really help me skip traffic when I'm heading to work or stop me from getting late.
I'm fairly certain that Magellan was the name of the falsified source in Green Zone...
Real time traffic for me
Multi tasking is nice, but that's easy now. I like being able to know what's around me when I'm in a new place. So location based services are my pick.
I like the idea of being able to multitask while using it
Real Time Traffic is huge for me. But being able fast app switch while still navigating is awesome.
Real time traffic and multi-tasking?? I want it!!
Location based offers for the savings win!!!
Oh if only I'd realized I was getting an iPhone and I would never have even looked at a stand alone gps!
Real-time traffic information and the fact that there is no additional charge for this feature!
real time traffic for $free.99 of course!
Multitasking is it for me.
The freedom to be able to go anywhere at a moments notice is what makes me dig this app, and it's from a trusted GPS brand already. I love the idea of stripping away another device and putting it on my phone.
I was actually about to buy a similar app on Saturday. My girlfriend and I were taking a trip to Atlantic city. I found it curious that there were so many brands that I hadn't heard of. Unfortunately, my girlfriend wouldn't let me get it.
Real TIme Traffic. It's the compelling reason (for me) to get GPS software. I need to know the best route!
Realtime traffic, no vehicle navigation anything should be without real time traffic.


text:
American Liver Foundation
Gastro—American Gastroenterological Association
Canadian Liver Foundation
Health Canada
Bilirubin. American Association for Clinical Chemistry Lab Tests Online website. Available at:
http://labtestsonline.org/understanding/analytes/bilirubin/tab/glance. Updated March 18, 2013. Accessed April 23, 2013.
Abnormal liver function tests—differential diagnosis. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated February 14, 2012. Accessed April 24, 2013.
Neonatal hyperbilirubinemia. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed. Updated February 15, 2013. Accessed April 24, 2013.
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
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text:
Friday, May 17, 2013
Coosaw Creek hosted and won the sixth match of the Charleston Area Men's Interclub Golf Association season.
Coosaw prevailed with 31 points May 6 to vault into first place in the yearlong standings. Berkeley was second with 24 points and Pine Forest third with 10 points. Trailing were Charleston National (6), Crowfield (2), Dunes West (1), Legend Oaks and Shadowmoss (both with -4), Miler and Wescott (both with -13), Stono Ferry (-17), Rivertowne (-21) and Charleston Municipal (-22).
Individual honors went to Jeremiah Evers of Stono Ferry who placed first with 11 points. Steve Bernard of Pine Forest, Sal Acosta of Coosaw Creek and Hank Miro of Crowfield all tied for second place with 9 points.
Full results can be found on chsinterclub.org.
Coosaw now sits on top of the season standings with 64.5 points but Pine Forest is right behind with 60.5. Trailing are Shadowmoss (52.5), Charleston National (47), Wescott (46) Crowfield (45.5), Dunes West (41.5), Miler (41.5), Miler (41.5), Rivertowne (36), Charleston Municipal (34), Legend Oaks (34), Berkeley (28) and Stono Ferry (27).
The next match is scheduled for 9 a.m. June 3 at Legend Oaks.
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text:
Wind: 3 mph
Sally J. Tremblay, 80, of Village Woods, Waitsfield, passed away on Tuesday, December 18, 2012. Born in Waitsfield on August 26, 1932, she was the daughter of the late Claude and Reta Wimble. On September 6, 1952, Sally married J. Edgar Tremblay in Moretown. Edgar predeceased Sally on December 2, 1997.
Sally began work part-time as an operator, while in school, at the Waitsfield Telephone Co. Following her graduation from Waitsfield High School, she continued in that vocation in Albany, NY, for two years and then again in Waitsfield. When she and Edgar married they owned and operated the Verd-Mont Dairy Farm in Waitsfield for the next 12 years before converting the large farmhouse into the Verd-Mont Farm Ski Lodge. Sally managed the ski lodge in addition to being the bookkeeper for Edgar's plumbing and heating business. Always the entrepreneurs, Sally and Edgar also developed and owned the Verd-Mont Trailer Park, which was part of the original farm.
A woman of strong faith, Sally was an active and devoted parishioner of Our Lady of the Snows Catholic Church of Waitsfield, was a member of the Couples Club in Waitsfield, was a member of the Mad River Valley American Legion Auxiliary Unit #75 and most recently a member of the Harry N. Cutting American Legion Auxiliary Unit #59.
Sally, simply put, was a people person. Gregarious, outgoing and a woman with strong opinions and a willingness to share them, she will be fondly remembered throughout the Mad River Valley as someone who was always willing to help another person no matter what the need. She embraced her entire family with love and caring that will remain with her children, their families and her special ones who called her "Grandma Sally."
In her leisure time, she enjoyed reading and cooking and was well renowned for her delicious baked beans.
Sally is survived by her children, Rita Jane Viens and her husband Stanley of Waitsfield and Thomas E. Tremblay and his wife Debra of Waitsfield; three grandchildren, Christopher Bombard, Andrew Bombard and Kari Ann Tremblay; five great-grandchildren, Cheyenne Borthwick, Abby Borthwick, Jonathan Bombard, Connor Bombard and Jordan Ashley Bombard; her brother, Calvin Wimble, and his wife Norma of Waitsfield; as well as nieces, nephews and extended family. Sally was predeceased by six brothers, Owen "Bud" Sr., Edward "Bunker," Kenneth, Robert, Leo and Donald, and four sisters, Sylvia, Kathleen, Caroline and Hannah.
A Mass of Christian Burial will be celebrated from Our Lady of the Snows Catholic Church in Waitsfield on December 29, 2012, at 10 a.m. with a reception to follow in the church parish hall. Inurnment will take place in Holy Cross Cemetery, Duxbury. The family requests that instead of flowers, memorial contributions would be appreciated to Central Vermont Home Health and Hospice, 600 Granger Road, Barre, VT 05641 (www.cvhhh.org) or to the Mad River Valley Ambulance Service, P.O. Box 305, Waitsfield, VT 05673. Assisting the family is the Perkins-Parker Funeral Home and Cremation Service in Waterbury. To send online condolences visit www.perkinsparker.com and Facebook.


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Donald Lokuta: Plato's Cave – Segal's Studio
August 6, 2013 (All day) - September 12, 2013 (All day)
Urban Arts Space, 50 W. Town St.
Donald Lokuta: Plato's Cave – Segal's Studio is the first exhibition of the work of Donald Lokuta (PhD The Ohio State University 1975) to explore the shared themes between two series of work, juxtaposing Lokuta's painted photographs based on Plato's analogy of the cave with large-scale photographic prints of the studio of sculptor George Segal.
Reception: Thursday, August 29, 5-7 pm
For more info, visit uas.osu.edu.
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Plus Blog
November 12, 2009
Thursday, November 12, 2009
Maths in a minute - combinatorics
And while we're on the topic of probability, let's answer one of those important mathematical question: how likely are you to win the lottery?
In the UK lottery you have to choose 6 numbers out of 49, and for a chance at the jackpot you need all of your 6 numbers to come up in the main draw. So the question is really how many possible combinations of 6 numbers can be drawn out of 49? There are 49 possibilities for the first number, 48 for the second, and so on to 44 possibilities for the sixth number, so there are 49 x 48 x 47 x 46 x 45 x 44 = 10068347520 ways of choosing those six numbers... in that order. But we don't care which order our numbers are picked, and the number of different ways of picking 6 numbers are 6 x 5 x 4 x 3 x 2 x 1 = 6! = 720. Therefore our six numbers are one of 49 x 48 x 47 x 46 x 45 x 44 / 6! = 13983816 so we have about a one in 14 million chance of hitting the jackpot. Hmmm...
But on a brighter note, we have just discovered a very useful mathematical fact: the number of combinations of size k (sets of objects in which order doesn't matter) from a larger set of size n is n! / (n-k)! / k!.
This sort of argument lies at the heart of combinatorics, the mathematics of counting. It might not help you win lotto, but it might keep you healthy. It is used to understand how viruses such as influenza reproduce and mutate, by assessing the chances of creating viable viruses from random recombination of genetic segments.
You can read more on combinatorics, including money (lotto), love (well kissing frogs) and fun (juggling and rubiks cubes) on Plus.
posted by Plus @ 1:18 PM
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November 6, 2009
Friday, November 06, 2009
Maths Inspiration event in Cambridge — November 24th
There are still places left at the Maths Inspiration morning event in Cambridge on 24th November, organised by Rob Eastaway. All Maths Inspiration events are aimed at sixth formers and more able Year 11 students.
The Cambridge events will be held in West Road Concert Hall on 24th November 2009, 9.45am - 12.30, repeated 1pm - 3.45pm. Speakers include Claire Ellis, Professor Chris Budd, Dr Hugh Hunt and Professor David Spiegelhalter, with talks including What have mathematicians ever done for us?, The Maths of breakfast, and The subtle science of uncertainty.
Tickets are £6 per attendee at all events with one teacher entitled to free entry for every ten students.
For full details of all events and to book tickets, please see the Maths Inspiration website, or contact email@example.com.
posted by Plus @ 2:24 PM
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November 2, 2009
Monday, November 02, 2009
What would you like to know about your Universe — The last online poll
This poll is now closed. The most popular question was: "How long is a day?" We will publish the answer in an article on Plus shortly. Thank you for taking part!
This is the last online poll in our series to celebrate the International Year of Astronomy 2009. Choose your favourite question from the list on the right, and we'll put the one that proves most popular to world-leading astronomers and cosmologists. The poll will remain open for a month and the answer will be published in a Plus article and possibly a podcast soon after.
The winning questions in our previous polls have been
The answer to the last question will be published on Plus shortly.
Labels: IYA2009
posted by Plus @ 4:10 PM
0 Comments:
October 27, 2009
Tuesday, October 27, 2009
Cancer is one of the major causes of death in the world (particularly the developed world), with around 11 million people diagnosed and around 7 million people dying each year. The World Health Organisation predicts that current trends show around 9 million will die in 2015, with the number rising to 11.5 million in 2030.
Cancer is the focus of much medical research, but perhaps surprisingly, mathematical research is also playing its part. Mathematician Mark Chaplain and an interdisciplinary team at the University of Dundee, have been awarded 1.7 million euros to develop a virtual model of cancer growth and spread.
Labels: Health and medicine, Latest news
posted by Plus @ 2:03 PM
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October 23, 2009
Friday, October 23, 2009
Maths student poster competition just launched!
If you're a maths student and feel like enthusing the next generation with your favourite bit of maths, then why not take part in the Further Mathematics Support Programme (FMSP) and Rolls–Royce plc third national poster competition.
Undergraduate or PGCE mathematics students are invited to design a poster, individually or as a group, which conveys the essence of a mathematical topic that has been covered at university by the designer(s). The poster should be targeted at school and college students studying AS or A level mathematics. Two winners will be chosen and receive £100 each, and their designs will be printed and sent out to over 2000 schools and colleges. The closing date is the 31st of March 2010. See the FMSP website for previous winners.
If this sounds interesting, then here are the rules. The poster should be mathematically accurate, attractively laid out, capable of enriching a course in AS or A level mathematics, and likely to attract school/college students to take mathematics (or mathematics-related subjects) at university. You can design your poster in any readily available software. Ideally, the page layout should be set to 59.4cm × 42.0cm, using either landscape or portrait format. The university's logo should appear in the top left corner and there should be a space 7cm high x 5cm wide in the top right corner for the FMSP logo. The bottom 2cm of the poster should be left blank. All images should be at least 300dpi.
Entries, as well as any questions about the competition, should be emailed to Richard Browne at firstname.lastname@example.com. The email must include the name(s) and full contact details of the designer(s). The poster design should be attached to the e-mail, in the form of an editable file. The FMSP reserves the right to edit the winning designs before printing.
Happy designing!
posted by Plus @ 9:45 AM
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October 22, 2009
Thursday, October 22, 2009
The idea that economics is all about the markets has been challenged by this year's award of the Nobel Prize in Economics. One half of the prize has gone to the political scientist Elinor Ostrom for showing that natural resources, like fish stocks or woodlands, can be commonly owned and still managed successfully. The other half of the prize has been awarded to the economist Oliver E. Williamson for demonstrating that the internal structures of firms and companies can be better at resolving conflicts than the open market. The award of the prize shows that economic theory can shed light not just on hard business transactions, but also on other forms of social organisation.
Labels: Latest news
posted by Plus @ 1:26 PM
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text:
Sunday, April 13, 2014
The Santee Cooper Board of Directors has named Fourth Circuit Judge J. Michael Baxley as senior vice president and general counsel, effective July 1. Baxley will replace James E. Brogdon, who retires June 30.
Baxley was elected resident judge in the Fourth Circuit in 2000, where he represents Darlington, Marlboro, Dillon and Chesterfield counties and has responsibilities for criminal and civil dockets for the circuit. Prior to becoming a judge, Baxley was managing partner of Driggers & Baxley law firm in Hartsville. He has been a practicing attorney in South Carolina since 1982.
Baxley has a bachelor of arts in political science from Clemson University and a juris doctor from the University of South Carolina. He is a member of the South Carolina, Darlington and American bar associations. He is married to Kristina Young Baxley.
Santee Cooper is South Carolinas largest power producer, the largest Green Power generator and the ultimate source of electricity for 2 million people across the state. To learn more, visit www.santeecooper.com.
The Gazette is pleased to offer readers the enhanced ability to comment on stories. We expect our readers to engage in lively, yet civil discourse. We do not edit user submitted statements and we cannot promise that readers will not occasionally find offensive or inaccurate comments posted in the comments area. Responsibility for the statements posted lies with the person submitting the comment, not The Gazette.
If you find a comment that is objectionable, please click "report abuse" and we will review it for possible removal. Please be reminded, however, that in accordance with our Terms of Use and federal law, we are under no obligation to remove any third party comments posted on our website. Read our full terms and conditions.
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text:
I want one of these. .40CAL is the next main military ammo which will be used through out. And, there is going to be plenty of it around in the future.
Rock River Arms: RRA LAR-40 .40 S&W
I want one of these. .40CAL is the next main military ammo which will be used through out. And, there is going to be plenty of it around in the future.
Rock River Arms: RRA LAR-40 .40 S&W
there is a fellow in the classified section today with three LPKs!
assembling an AR is very easy. and you save a lot of money as well as opposed to buying one.
lets do a run down complete upper from JSE $430 when in stock--
LPK $83 from classifieds--
m4 stock kit $55
out of that you'll need a lower, and some mags there are still some good mags around for say $28 each --expensive but not insane like the $100 prices some places are asking-- you might get lucky and get some mags retail as they do pop up for about retail price of $18 from time to time.
so were at about $560 + 100 for three mags that is $660 + a lower
and the lower is a snag --they do sometimes come up for sale at around $200
sights.slings, free float quad rails and so on all extra price--LOL
so if you build one today with three mags and reasonably good mags --it is probably going to set you back $880-$900+
one of those $500 a1 kits is going to need a barrel --say $160, or does it come with a barrel? then a lower --lets say $200 and mags another $100
so $500+ $200+$100 = $800 that is if they come with a barrel-- the a1 might be the cheapest option.
the big snags are LPKs, lowers, and finding a complete upper in stock anywhere at a retail price.
I know a man who has 2 M4s. He says he is thinking of selling them before the government thugs ban them. He also has a lot of ammo. He claims to have around 50 high cap mags for them. He also has a lot of spare parts. I'm sure that he would want $4,000 and up for the whole pile. If I can come up with the money, I may try to buy the whole pile.
Are they high cap mags or standard capacity mags meaning what the gun was meant to fire?
"What country can preserve its liberties if its rulers are not warned from time to time that their people preserve the spirit of resistance?" -Thomas Jefferson-
"Our rights come from our humanity and may not be legislated away -- not by a vote of Congress, not by the consensus of our neighbors, not even by agreement of all Americans but one." Judge Andrew P. Napolitano
I'm sure that they are the standard mags-30 shot! I just get in the habit of saying hi cap so that everybody knows. But, you are right! We should call them what they are-"Standard M4 magazines!
well mags ain't all that short--
the things that are very short supply in order of importance for an ar-15 set up
#1 AMMO --223/5.56 is very short supply and very expensive --the outlook for the future is not good.
#2 lowers & LPKs --there overpriced and scarce
#3 everything else mags, uppers parts--they were plentiful last year few around today and their no deals anymore.
you pal with the ar-15s could be a deal if he has got enough ammo--LOL
today it ain't gonna take all that much ammo to make a $1,000 worth!
For several years (while I was working) I purchased a few boxes of ammo every payday. One time it was .223/5.56. Another time .308. Sometimes I would buy a few boxes for my various handguns. I bought a lot of .22LR. I also purchased a number of boxes of 12 gauge ammo for my shotguns. I have several cases of 7.62X39 for my AK and SKS. So, I think that I now have enough ammo to last me the rest of my life if I don't waste it. I'll use my .22s for practice.


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New Steve Jobs action figure is ultra-realistic, may not last long
Forbes reports that a new Steve Jobs action figure from Inicon is so realistic, the photos actually make it look real. The action figure comes with the following details.
- one realistic 'head sculpt;'
- two pairs of glasses;
- a 'highly articulated body;'
- three pairs of hands;
- one tiny black turtleneck;
- one tiny pair of blue jeans;
You can purchase the action figure from Inicon's website, however, we're not exactly sure how long Apple's hordes of lawyers will let this one last -- go grab it while it's still up!
(Note: Inicon seems to be down due to the large amount of traffic they've seen)
Have something to say about this story? Leave a comment! Need help with something else? Ask in our forums!
Reader comments
New Steve Jobs action figure is ultra-realistic, may not last long
Wow! Is he completely insertable?
I've got a couple good guesses what the "C" stands for in your name, but I'm going to bite my tongue. You should've done the same.
I didn't say we're not a cult. Did somebody say we're not a cult?
I get to keep my robes, right?
I wouldn't mind picking one of these up just as a collectors item, but the In Icon website has been down since this story originally broke on Gizmodo. I've tried it at all hours of the day, and I can't help but this this may be fake. Cool looking figure if real.
Oh, and when is TiPB going to change back their comment system? It seems the trolls have come out of the woodwork lately.
What I don't understand is how a toy company can nail his likeness so well, while that bovine-jawed, bronze "thing" in Hungary has haunted me with nightmares for days. Clearly they have a better artist.
Andrew, Inicon is a design concept company located in Germany. This is made by In Icons.
I tryed doing this with an apple // and moutain hardware gizmos back in the day ... and failed. technology rocks! now lets implement voice mail on the repeater.
These are great review for us to follow to sustain a proper weight.At first I really don't get the brief explanation of products, but know I already got it,all the products are dietary which will help our body to lose or gain weight safely.Kate Brown Wilson recently posted..VZ 58
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I said something goofy then thuoght of something els and had pressed post to quickly I didn't mean I would by the frame over the iPad I meant it in the sense of I would be the cheaper frame, and continued to say that the price goes up if you get one that can be at all useful and why I click on the video is cause I value Chris' opinion, and I usually agree with him so when we don't agree on something I wait for the piece of information that will change my mind
I don't even know how I ended up here, but I thought this post was great. I do not know who you are but definitely you're going to a famous blogger if you are not already ;) Cheers!


text: Urban Decay Strip Eyeshadow ($17.00 for 0.05 oz.) is described as a "very metallic bluish-silver." The color itself is a silvered, gray-blue with a bright metallic sheen and shine. It's like an overcast sky with blue and silver shot through it. It is less blue than Urban Decay Mary Jane but lighter and less gray compared to Bare Escentuals Vapor. Strip has nice color payoff, too, and when you combine that with a stellar texture, you get an eyeshadow that impresses.


text:
Pretty Little Liars
Watch Pretty Little Liars Online: Season 3, Episode 19 (VIDEO)
The drama on Pretty Little Liars reached a boiling point during Season 3, Episode 19, but if you weren't there to catch the drama unfold in real-time, Wetpaint Entertainment has got you covered.
Watch the full episode below, but in case you need a refresher, here's what's been going down for the Liars in Rosewood.
Spencer is still continuing her downward spiral after she discovered Toby's betrayal. Now, she's taking out her frustrations on Mona, who's doing everything in her power to make her crack -- including telling Wren she's worried about Spencer's mental health.
Meanwhile, in Ezra's absence, Aria and Wesley grow closer, which isn't necessarily the best news for Ezria fans.
As for Hanna, she brings Caleb face-to-face with his father Jamie (previously thought to be his uncle), and although Caleb resists at first, father and son ultimately hit it off. Go Hanna! If only Emily and Jason's venture could have been as successful. After some serious snooping -- and a shocking discovery about CeCe and her connection to Ali -- something goes terribly wrong and Jason has to pay the consequences.
Watch the episode below to find out!


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Web Filtering
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Secure Web Gateway
Bloxx Secure Web Gateway provides unsurpassed Web content filtering with advanced malware protection to minimize Web-based security threats.
Email Filtering
The Bloxx Email Filter isn't just an anti-spam appliance; it effectively manages personal, non-business emails to make email productive again.


text:
Baby Change Stations have been installed in all of the washrooms throughout Rogers Centre. For those seeking extra room or privacy, Family washrooms are available near Sections 134, 238 and 539.
Booster seats for young children are available at all Guest Services locations on a first-come, first-served basis. Guests are asked to leave their driver's license until the seat is returned.
Parents may bring children under the age of two into Rogers Centre for most events without a ticket for the child. These children must sit in the lap of the accompanying adult and not occupy an additional seat. Any guests two years of age or older must have a valid ticket. Children having difficulty seeing from their seat can obtain a booster chair from Guest Services locations, available on a first-come, first-served basis.
Family washrooms are available for all guests requiring a little extra room or privacy. These washrooms are located near Sections 134, 238 and 539. Designated Nursing Rooms can also be found at these locations.
If you have any issues gaining access to either of these areas, please ask a staff member for assistance or visit one of our Guest Services locations to report the inconvenience.
For more information on how to join the Jr. Jays Club and all the benefits our younger fans receive please call the Jr. Jays Club Information Line at 416-341-1715.
2013 Jr. Jays Club membership information will be available shortly!
Kids 14 and under get a day all their own at the ballpark with Jr. Jays Saturdays. At every Saturday home game, kids can visit our Jr. Jays Zones located on the concourse, as well as take part in our Outdoor Program that begins outside Gate 10 from May 25 to August 31. Jr. Jays also have the opportunity to be randomly selected by the J FORCE to participate in our pregame Starting Line-Up and Seventh Inning Stretch.
Upon entrance to the stadium, all parents/guardians are encouraged to visit any one of our Guest Services locations to obtain a Misplaced ACE Wristband. The child's section, row and seat number, along with the parent/guardian's contact number, will be recorded on the wristband by Guest Services staff. All Toronto Blue Jays and Rogers Centre staff are directed to escort lost children wearing a Misplaced ACE Wristband to their seats.
For the benefit of guests wishing to enjoy a Blue Jays game free from alcohol in their section, the club has designated parts of Sections 141/142, 237/238 and 520/521 (First 14 rows only) as non-alcoholic.
On Jr. Jays Saturdays and after other select games, kids 14 and under can come down to the field postgame and run the bases like the pros! Jr. Jays are invited to line up following the game at Sections 108, 208 and 508. Each Jr. Jay must be accompanied by an adult and will be able to run the bases once. Adults must accompany their kids, yet unfortunately are unable to run the bases themselves.
The Toronto Blue Jays and Rogers Centre welcome guests with baby strollers, but kindly ask that all strollers be checked at a Guest Services location and not stored at the guest's seat or at the top of the aisle. Our 500-Level guests who visit the ballpark on the weekend are welcome to stop by our Jr. Jays Stroller Valet, where an Ambassador will gladly check your stroller and provide you with a claim ticket to exchange once you and your family are ready to leave.


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Welcome to Heal's
Heal's specialises in well-priced, high quality furniture including designer chairs, dining chairs, dining room benches, stools and bar stools with a modern and contemporary style. With over 90 designs to choose from, you can be assured that your dining room furniture will be unique to you.
From sleek leather to classic wooden chairs and stools, many of our contemporary dining chairs & stools are made and designed in Britain. We also have a wide range of designer dining room furniture, dining tables and dining chairs from leading brands including Vitra, Ligne Roset, Calligaris, Ercol Originals and Kartell.
Read our wood care guide for information how to care for your designer dining chairs and stools. Solid wooden furniture looks great, ages beautifully and, if you look after it, lasts forever.
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This hotel has a great location for either the city or Dartmoor, and sits in delightful gardens. Bedrooms are spacious, all with garden views and some with impressive balconies. There is a choice of d...More about Moorland Garden Hotel
High quality, budget accommodation ideal for both families and business travellers. Spacious, en suite bedrooms feature tea and coffee making facilities, and Freeview TV in most hotels. Internet acces...More about Premier Inn Plymouth East
A historic landmark, this city centre hotel is conveniently located. The spacious public areas include a popular bar, comfortable lounge and multi-functional ballroom. Bedrooms, many with far-reachin...More about BEST WESTERN Duke of Cornwall Hotel
The friendly animals that freely roam the courtyard add to the relaxed country style of this delightful inn. The spacious bedrooms are well equipped, and freshly cooked dinners are available in the ba...More about Crooked Inn
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Julia Roberts Goad
Staff Writer
"Work is something you do, not someplace you go."
That is the motto of Kentucky Teleworks (KT) is a program administered by the Eastern Kentucky Concentrated Employment Program (EKCEP).
Kentucky Teleworks diversifies the local economies of Kentucky by bringing in high-demand, high-growth telework jobs while recruiting and preparing Kentucky workers for those jobs, making it possible for more Kentuckians to have careers while staying in their local communities, raising their families, and contributing to the state's quality of life.
The terms "telework," "telecommuting," "flexible workplace," "remote work," "virtual work," and "mobile work" are all used today to refer to work done outside of a traditional office environment. In most cases, teleworkers work from home on a computer that is linked to their employer.
The advantages of working from home are numerous, and include saving the cost of commuting, reduced child care costs and a better balance between work and your home life.
Employers also benefit from telework. Increased productivity from they're happier employees, reduced operational costs, including real estate, facilities, business travel, and other overhead expenses, and liability and health insurance costs go down.
The flexible working conditions offered by telework make it easier to attract and retain a skilled workforce enhancing productivity, creativity, and the quality of work.
During a period of high unemployment, working from home is an attractive proposition. More than 17,000 work-from-home scams were reported to the Internet Crime Complaint Center in 2011, costing victims more than $20 million. On average, that was two complaints and $2,297 lost per hour.
KT is a way for Kentuckians to find opportunities to work from home for a legitimate company. The jobs listed through the agency are researched thoroughly and are often taken from employment sites that are endorsed by agencies like the Better Business Bureau and the Telework Coalition.
Teleworkers do their work in very much that same way as they would in an office setting today: via a computer linked to their employer's server. An effective home office — including proper furniture, computer equipment and accessories, in a quiet space — will allow you to be a productive and successful teleworker.
Telework jobs cover a wide variety of different skillsets and schedules, just like the traditional workplace. Available jobs range from entry-level work with limited educational and skill requirements to highly skilled professional positions requiring postsecondary degrees and special certifications.
The process begins with registering with KT, which is free of charge. When you sign up you will automatically be given free access to all that Kentucky Teleworks offers. You will also be contacted by a representative of EKCEP and offered some of the free services that EKCEP provides, such as Job Clubs, career advising, resume assistance, skills testing, and training and education assistance.
For more information, visit http://kentuckyteleworks.com, or their Facebook page, http://www.facebook.com/kentuckyteleworks.


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- Brieftaube (3) (remove)
- Biowissenschaften (3) (remove)
- Homing in with GPS (2000)
- Flight tracks of homing pigeons measured with GPS (2001)
- Flight paths of homing pigeons were measured with a newly developed recorder based on GPS. The device consists of a GPS receiver board, a logging facility, an antenna, a power supply, a DCDC converter and a casing. It has a weight of 33g and works reliably with a sampling rate of 1/s with an operation time of about 3 h, providing timeindexed data on geographic positions, ground speed and altitude. The data are downloaded when the bird is recaptured. The devices are fixed to the birds with a harness. The measured complete flight paths show many details: e.g. initial loops flown immediately after release and large detours flown by some pigeons. We are here presenting 3 examples of flight paths from a release site 17.3 km Northeast of the home loft in Frankfurt. Mean speed in flight, duration of breaks and length of the flight path were calculated. The pigeons chose different routes and have different individual tendencies to fly loops over the village close to the release site.
- The GPS flight recorder for homing pigeons works : design and first results (2000)
- This paper describes a first version of the GPS flight recorder for homing pigeons. The GPS recorder consists of a hybrid GPS board, a patch antenna 19*19 mm, a 3 V Lithium battery as power supply, a DCDC converter, a logging facility and an additional microprocessor. It has a weight of 33g. Prototypes were tested and worked reliably with a sampling rate of 1/sec and with an operation time of about 3 h. In first tests on homing pigeons 9 flight paths were recorded, showing details like loops flown immediately after the release, complete routes over 30 km including detours, rest periods and speed.


text: I read this for the first time on the weekend. As a person who spends the majority of the day sitting this really got me thinking. I have been googling it and reading about it. It's been seven years since I became a medical transcriptionist and now I am starting to think that my job is slowly killing me. Between sitting on the ride to work, sitting all day at work and then sitting again on the way home plus sometimes feeling so fatigued that I just want to sit in front of the boob tube when I get home I am kinda thinking maybe I need a new line of work. I do enjoy my job but I care about my health, too. Looks like I better focus on squeezing some more activity into my day unless I want to die early. Has anyone here on the message board heard that expression yet? i.e. "Sitting is the new smoking" or is this just the latest way to get people all riled up?


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Simply season, set and slowly simmer for a hearty meal.
Buy this ingredient
1. Place pork chops and onions and mushrooms in 5 to 6 qt. slow-cooker.
2. Top with condensed cream of mushroom soup and water and season with salt & pepper.
3. Cover and cook on low 6 to 8 hours or until pork is tender.
Tip: Stir in a spoonful of sour cream before serving. Great served over prepared rice or wide egg noodles.
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|Picturebook Playhouse
Event Type: Children's Storytime
Date: 4/30/2014
Start Time: 2:30 PM
End Time: 3:00 PM
Ever wished your favorite stories could come to life? In Picturebook Playhouse, they can! Each week a different picture book is selected and re-enacted. A great way to build group cooperation skills and boost imagination through role play! For ages 4+.Library: Oak Park Public Library Maze Branch
Location: Meeting Room - Maze Branch
Contact: Maze Branch Library
Contact Number: 708.386.4751
Presenter: Jessica B.


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Gear Review
warm but poor fit depending on your legs
- Gender: Male
- Familiarity: I've used it several times
5'8" 150lbs, bought a small. it was a little too long and loose. the fabric does its job but cannot warm what it doesn't cover: the crotch. if you're riding in cold weather, you need cold weather tights/knickers and cannot get by with just these and a pair of gossamer summer shorts.
that said, these did actually warm my legs; the arrangement of windproof panels in front of the knees did work nicely.
even when i wore the warmers under my shorts, they seemed to slip down even on relatively short (10-20 miles) rides in 40 degree weather.
John Heineken
Regarding leg warmer slippage (so irritating)... try this trick offered by mar2596868: use skin balm. I use organic "Badger Balm" made in New Hampshire (avail online or at natural food stores). It works!
View More Details on Pearl Izumi P.R.O. Barrier Leg Warmers


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The Liverpool legend will make his final appearance against Redknapp's men on Sunday, ending a 16-year career.
And Redknapp, who will remain in charge at QPR next season despite the club's relegation to the Championship, has paid tribute to the 35-year-old.
"Jamie Carragher has been one of the great pros. He's a top, top professional and a great guy. He has a great knowledge of the game and is a real leader," he said.
"Everybody would love a Jamie Carragher in their team. If I had him in my team next season we'd get promoted. That's how highly I rate him.
"He's the type of player who will drag the team along for you. There aren't many of them around.
"Liverpool are very lucky to have had him and Steven Gerrard at the club. They've been brilliant.
"Liverpool's his team and I imagine he's never even thought about leaving the club. It will be a full house for him at Anfield.
"He's been massive to Liverpool, one of their most important players. He's up there with all their great players over the years - Tommy Smith, Emlyn Hughes and Phil Thompson."
Redknapp expects to make major changes to his squad this summer, but insists strikers Bobby Zamora and Andrew Johnson will be staying.
"Bobby and Andy have contracts, where are they going to go? I expect them to be here. They're two good players and I'd like to keep them," he added.
"They have contracts so I don't see any reason why they won't be here


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• One of six juniors on the 2012-13 squad
• Named to the Southern Conference Academic Honor Roll
• Named to the Chattanooga Dean's List both semesters
• Named to the Chattanooga Athletics Director's Honor Roll both semesters.
Career Highs
• Points: 10 vs. Western Carolina (1/22/11)
• Rebounds: 3 vs. Idaho State (11/24/11)
• Assists: 2 vs. Davidson (2/12/11)
• Steals: 2 (3) last at Samford 1/19/11
• Blocked Shots: 1 (3) last at Furman (2/7/11)
• Minutes: 21 (3) last vs. Western Carolina (1/22/11)
• Field Goals Made: 4 vs. Western Carolina (1/22/11)
• Field Goals Attempted: 9 vs. Western Carolina (1/22/11)
• 3-Point Field Goals Made: 2 vs. Western Carolina (1/22/11)
• 3-Point Field Goals Attempted: 6 vs. Western Carolina (1/22/11)
• Free Throws Made: 3 vs. Idaho State (11/24/11)
• Free Throws Attempted: 5 at Tennessee (11/15/11)
Why do you wear No. 24?
"Kiara Smith originally had my number (32)."
Do you have a nickname? How did you get it?
"Destina- not so sure but Alex [Black] came up with it. DB - from my high school coach; Dest- Short for Destiny, Twin- Taylor [Hall] gave it to me because we dress alike on the court."
What is something people may not know about you?
"I'm a great singer, whenever you can't hear me."
What is your favorite TV show?
"The Voice."
What song gets you pumped up before a game?
"Anything 2 Chainz is on!"
Who is your favorite musical artist?
"Chris Brown"
What is the first thing you purchased from the UTC Bookstore?
"A T-Shirt from the clearance rack."
What is your favorite food?
"Parmesan Crusted Chicken"
Have you ever visited another country? If yes, what one(s)?
"Mexico, last year for our Thanksgiving tournament."
Would you like to be famous?
"Yes, because then I wouldn't have to wait in line for the latest shoes."
Are you a morning or night person?
"I'm a night person for sure!"
What actress would play you in a movie about your life?
"Sandra Bullock because she's hilarious!"
What cartoon character describes you best?
"Myra, according to my mother- she said I use to pester dogs when I was younger."
Do you speak any foreign languages?
"Two years of simple Spanish in high school."
Are you a beach, city or country person?
"I love the city because you can shop so much, but I do like my sun."
If you could live anywhere in the world for one year, were would it be?
"Somewhere overseas, it's so different from what I've heard from former players."
If you knew you could try anything and not fail, what dream would you attempt?
"Become a singer! I love to sing but I'm not very good once I hear myself."
If you didn't play basketball, what other sport would you play?
Name three items you would want most if stranded on a deserted island.
"Unlimited supply of battery life on my phone, bug spray, Smashing Strawberry Minute Maid juice."
Who is the funniest player on the team and WHY?
"To hard to choose one, EVERYBODY is HILARIOUS! I love them."
The 2012-13 regular season tips off November 9 at the McKenzie Arena against Tennessee. Season tickets are on sale now at the McKenzie Arena box office or online at GoMocs.com. Single-game tickets go on sale Monday, October 15.
Join the Mocs Club today and take advantage of your opportunity to purchase up to six tickets to the Lady Mocs game vs. Tennessee on Nov. 9. All Mocs Club members are eligible. New members who join at the Starter Moc level ($75) can take advantage of this offer.


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American Revolution: Continental Congress Photo Gallery and related media
American Revolution: Continental Congress
Drafting the Declaration of Independence, by Jean Leon Ferris
From the left, Benjamin Franklin, John Adams and Thomas Jefferson. Franklin and Adams helped revise the Declaration of Independence, which drew from established political philosophy in justifying the need for independence.
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PRESTONSBURG — An order to freeze former David School director Danny Greene's credit card was issued in Floyd Circuit Court, after the school alleged questionable expenses charged to the account.
On Wednesday, The Times reported on a motion filed Dec. 14 by the David School's attorney, Michael Endicott, which noted an existing credit card account with a bill of over $2,000. Prestonsburg attorney Ned Pillersdorf, who serves as vice chairman of the school's board, said in an affidavit that the charges appear to be mostly unrelated to school functions, and included charges in at least five different states. At least one of the charges listed on the account was a single charge of $32.35 to Adult World Factory Outlet, in Widener, Ark.
During the court hearing Friday, Judge Johnny Ray Harris said the credit card charges were troubling and issued a court order freezing the account.
The motion also called into question some tax liability with which the David School had been saddled. According to Pillersdorf, Greene subjected the school to a tax bill of $33,919.33 by failing to pay withholding tax to the government, even after it had been deducted from employee paychecks, and failing to file required forms.
"I have no hesitancy in representing to the court, that he (Greene) caused these charges," Pillersdorf siad.
Pillersdorf was accompanied in court by attorneys from the state Attorney General's Office, who indicated they would refer the matter of the tax liabilities to the prosecutorial division to address criminal aspects of the case. They also said they would try to help the David School with resolve the matter with the Internal Revenue Service.
A final item of the motion was addressed in court, concerning a piece of property the school bought from Greene in 2005, at a price of $157,000, consisting of two tracts of land. Pillersdorf says that a clerical error only accounted for one tract in the actual deed.
Pillersdorf said that school is currently in negotiations to sell the property and asked that a quitclaim deed be issued to establish both tracts as being part of the property to be sold. Greene and his wife only signed one of the deeds, leaving ownership of the other piece of land in question. The motion asks for Greene and his wife to sign a quitclaim deed for the other piece of land so that the sale could move forward. Judge Harris agreed that the deed in question was for both tracts of land, and entered an order for the Greenes to sign a quitclaim deed.
Pillersdorf added that with the sale of the property, and a resolution to the tax liability issue, the school could be financially on solid footing again.


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We were at a Chicago Wolves game and had no idea they had adoption nights. Between periods we decided to just take a look for fun. We found an adorable 4-month-old puppy by the name of Froyd, fell in love with him, and took him home.
First thing we did was rename him Skates after the Wolves mascot! It seemed fitting. Now, anytime someone meets him and they ask how he got his name we have a great story to tell. He has been the best dog we have ever had!


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Wednesday, October 9, 2013
The Town of Moncks Corner does not like drama.
Especially when preparing its budget for the coming fiscal year.
"We presented our new 2013-2014 budget to council in June and it passed its two required meetings by August," said Town Administrator Marc Hehn.
The process was drama free.
Any debate or discussion about what should stay and what should go was handled quietly and respectfully. The $5.85 million budget went into effect on Oct. 1 without any need for continuances.
"The way we do this is we have more than one budget meeting," said Moncks Corner Mayor Bill Peagler. "We schedule the meetings so that everybody can attend. Holding budget meetings with department heads at 10 in the morning when every member of council is at work is not conducive to a smoothly developed budget."
Included in the new fiscal year budget was the provision for a 2 percent merit increase to go into effect in April 2014 following a mid-year budget review.
"The funds are designated for a merit raise for town employees," said Lisa Hancock, town accountant. "It is not a cost of living increase. The funds are used at the discretion of department heads and are performance based increases."
Hancock added that if funds are not available after the April mid-year review, the 2-percent raises would not occur. An additional $28,595 is needed for the merit increases.
Also included in the FY 2013-2014 budget is $1.98 million for completion of Phase I of the Moncks Corner Regional Recreation Complex; equipment for the Moncks Corner Fire Department; funds for the proposed Moncks Corner Fire Station in Foxbank; and four new patrol cars for the Moncks Corner Police Department.
The mayor said that he is pleased with the progress of the Regional Recreation Complex but as he told the Berkeley County Legislative Delegation, the facility is not just a benefit to the town of Moncks Corner, but to Berkeley County as well.
"I asked them to think outside the box when it came to finding funds for this complex," he said. "This is something that will bring revenue countywide. We don't have enough space in our hotels and restaurants here so when we host tournaments people will also be eating and staying in hotels in Goose Creek and Summerville as well."
With the dry weather, construction has begun on the new concession stand and press box and has continued on the four ball fields.
"Obviously it's moving forward and is accelerating with the dry weather," Peagler said. "I'd rather have had the first phase completed in August so it wouldn't push against the start of the 2014 season, but just to see it advancing is very satisfying."
Peagler added the town's budget philosophy is simple - keep the taxpayers happy.
"We are a conservative council, myself and members of council, and we relay that philosophy to our department heads so we can produce a budget that makes the best economical use of the taxpayers' money," he said. "After all, they are our customers and we need to keep our customers happy."
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Timeout...Check Out New Images From NFL Series 32
Series Includes New Big Head Collector Level Figures
Monday, June 24, 2013
McFarlane SportsPicks' NFL SERIES 32 is definitely offering up a wide mix of NFL superstar favorites, and some new faces never before seen in the SportsPicks universe.
Returning to the line-up, Denver Broncos QB Peyton Manning, Houston Texans RB Arian Foster, Washington Redskins QB Robert Griffin III, and Baltimore ravens WR Ray Rice, each impacted their team and all captured a coveted spot in the 2012 NFL Playoffs.
Making their McFarlane's SportsPicks debut in 2013, San Francisco 49ers TE Vernon Davis, Cincinnati Bengals QB Andy Dalton, Pittsburgh Steelers WR Antonio Brown, and Green Bay Packers WR Jordy Nelson, definitely earned a spot of action figure immortality!
All penalties aside, let's take a look at exclusive images of NFL SERIES 32.
RAY RICE - Baltimore RavensROBERT GRIFFIN III - Washington RedskinsANTONIO BROWN - Pittsburgh SteelersJORDY NELSON - Green Bay PackersVERNON DAVIS - San Francisco 49ersARIAN FOSTER - Houston TexansANDY DALTON - Cincinnati BengalsPEYTON MANNING - Denver BroncosPick up all these NFL SERIES 32 figures at Amazon.com, Big 5, Cardstadium.com, Clarktoys.com, FYE, Hastings Entertainment, Toys 'R' Us, Toys 'R' Us Canada, Toys 'R' Us Express this August!
Stay tuned to www.mcfarlane.com for the latest news and info on all the upcoming products from McFarlane Toys.
McFarlane Toys
McFarlane Toys is the fifth largest action figure manufacturer in the United States. Established in 1994 to manufacture and sell action figures based on founder Todd McFarlane's comic book character Spawn, the international award-winning company has expanded into licensed products to become one of the premiere action figure producers on the planet.
Check out the McFarlane Toys' Catalog, where you can see all of our current figures, previews of upcoming toys, and even a massive archive of every action figure we've ever made.
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