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My Style
My Style
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45 adapters, in all their forms.
Tattoo Ideas, Celtic Symbols, Remember This, First Tattoo, 45 Records, A Tattoo, Records Players, 45 Adaptive, Vinyls Records
One of these 45' record inserts will be my first Tattoo, when I turn 45 in a few months...
45 adapters -- Almost makes me want to get a tattoo of #5
Record adapters. Cap tattoo idea
These are not Celtic symbols!
Remember these? 45 vinyl records
I remember this
Adapters to put in the center hole of 45 records to play on record players
Surface noise.
Music, Legends, Johnpeel, Life Ha, John Peel, Vinyls Fees, White Noi, Vinyls Records, Surface Noi
John Peel vinyl quote
"Somebody was trying to tell me that CD's are better than vinyl because they don't have any surface noise. I said, 'Listen, mate, LIFE has surface noise." #vinyl #records #music #love
Different Kitchen Tumblr - The late, legendary John Peel on why music on vinyl is still so great!
love this sound
Vinyls Collection, Collection Vinyls, Album Sales, Crates Dig, Things Vinyls, Listening To Music, Vinyls Collector, 13 Things, Dusty Fingers
Flipping through records in a used bin and having no idea what the next thing you see will be. | 36 Things Vinyl Collectors Love
Album sales in a particular genre of music go up as the music gets simpler. | 13 Things You Probably Didn't Know About Listening To Music
dusty fingers ~
crate digging http://www.discogs.com/seller/RageVinyl
You thumb through every single record bin in every shop because you never know what you might find. | 18 Signs You Are Addicted To Collecting Vinyl
24 Things You Should Know Before Starting A Vinyl Collection
Lover Lover Ring by I Adorn U S+A
Cute Rings, Idea, Initials Rings, Love Rings, Heart Rings, Lovers Rings, Lovers Lovers, Initial Rings, Engagement Rings
#Lover #Love #Ring <3 I LOVE this old fashion idea
Love heart Ring
Lover + Lover Ring = Cute. #tiffany tiffany engagement rings on ebay #tiffany second hand tiffany rings london
Lover Lover Initial Ring Love this idea
Lover Lover Ring... tree carving initials ring
Cute ring
Heirloom Clutch - Rib and Hull
Fashion, Ribs, Heirloom Portfolio, Style, Leather Wallets, Notebooks, Leather Clutches, Leather Accessories, Leather Bags
#leather #accessories
leather bag | Heirloom Portfolio | Cognac
Gorgeous color and style- Just need it in a smaller size, like this one http://www.ribandhull.com/products/wallet-pouch-off-white - Portfolio in Cognac | Rib & Hull
Chic Leather Wallet
Heirloom Portfolio brown leather clutch
HEIRLOOM PORTFOLIO | COGNAC - "This is the perfect pouch for holding your papers, notebooks, iPad or other e-reader. The premium Italian vegetable tanned leather will make it truly stand out from the rest. Best of all the leather will age beautifully."- $160
Gucci Bags, Fashion Merchandi, Mothers Day Gifts, Nada Sawaya, Wooden Clutches, Design Handbags, Fashionmerchandi, Leather Handbags, Clutches Bags
Mother's Day Gift : Wallet. Looking for a gift for you mother, you can always consider a wallet as a gift [Oishi Aktar]
Nada Sawaya/ wooden clutch bags
Mexican Embroidery
Black Backgrounds, Inspiration, Peacock Flowers, Folk Art, Mexico, Colors Palettes, Mexicans Embroidery, Folkart, Crafts
Mexican bird. #colour, #folkart
black background pops this color Mexican embroidery
Mexican embroidery— see what I mean? All regional applications of embroidery in Mexico are so exquisite! I grew up/live in a place where Mexican textiles (some antique!) are abundant, yet I never grow tired of the beauty of Mexican design.
Crafted - Mexican embroidery
mexican embroidery COLOR PALETTE
inspiration - Mexican embroidery.
Folk Art Embroidery
Nice, it is.
Stars War Origami, Centimet Tall, Crafts Ideas, Awesome Origami, Paper Art, Yoda Origami, Origami Yoda, Yoyo Ferro, Starwars
adorable and amazing origami Yoda (StarWars paper art)
Yoyo Ferro, ORigami Yoda, Star wars Origami, Fumiaki Kawahata, sustainable art @The Product Farm
This Awesome Origami Yoda is Just 7 Centimeters Tall! Yoyo Ferro Yoda Origami – Inhabitat - Sustainable Design Innovation, Eco Architecture, Green Building
oh yeah
Vintage Comics, Comics Book, Vintage Music, Vinyls Club, Records Covers, Music Comics, Book Covers, Romances Comics, Vinyls Records
"Vinyl Record Club"...the first rule of Vinyl Club, don't talk about Vinyl Club... VINYL RECORD STUFF
Hi-School Romance comic record cover
Familia H*E*A*L*S*
Memories Tablet, Vinyls, Ideas, Quotes Inspiration, Scrapbook Rooms, Brass, Plaques, In This Houses, Pictures Wall
Have this in a different version hanging on the wall in my scrapbook room!
In this House We do second chances...
Love the idea of doing vinyl or stenciling this on a wall... <3
Clocks Music, Pavel Sidorenko, Clocks Design, Vinyls Art, Wall Clocks, Clever Ideas, Favorite Pin, Awesome Art, Vinyls Clocks
#black #vinyl #art: #scooter and #piano
Omega Vinyl - Vinyl wall clock: Mood, $75.00 (http://www.omegavinyl.com/products/Vinyl-wall-clock:-Mood.html)
Vinyl Clock By Pavel Sidorenko Part 2
design-dautore.com PAVEL SIDORENKO in Clock Design
Vinyls Addiction, Posters Design, Graphics Design, Posters Art, Music Graphics, Vinyls Soul, Music Genre, Soul Music Posters, Posters Ads
Vinyl soul
Posters of musical genres using one graphic element and one typeface
Vermont Wooden Spoon Co.
Beautiful Wooden, Toms Colicchio, Openski Exclusively, Wooden Kitchens, Hands Carvings Wooden, Kitchens Gadgets, Wooden Utensils, Vermont Wooden, Wooden Spoons
Unusual Kitchen Gadgets | Unique Kitchen Gadgets, Utensils, & Accessories / hand-carved wooden ...
Beautiful Wooden Spoons.
OpenSky Exclusive: Vermont Wooden Spoon Co. : If you are a cook, it is something about your wooden utensils that make the experience so much more lovely. This collection had everything that can be used for everything!
Carved wooden kitchen utensils. Love it! Honey... can I use the credit card????
OpenSky Exclusive: Vermont Wooden Spoon Co. from Tom Colicchio on OpenSky
So cute!
Rock Feet, Footprints, Foot Prints, Cute Ideas, Rocks Feet, Step Stones, Gardens, Things, Crafts
happy rock feet. Cute idea for the garden!
#Cute #Garden #Rocks #Feet #Footprints #Simple #Easy #DIY
Rock Footprints Cool Idea :) I have a thing for rocks, and trees. Nature girl I guess. This idea would be awesome in a garden. :)
Rock Feet - fun beach craft! This would be fun for stepping stones in a garden, or embedded into a patio walkway. The link for this doesn't work.
Rock feet! fairy foot prints in the garden :D
I love my silver 45Adapter necklace
Pendants Necklaces, Adaptations Spindle, Rpm Vinyls, Records Adaptations, Spindle Replica, Replica Pendants, Silver Tone, Adaptations Necklaces, Vinyls Records
45 Rpm Vinyl Record Adapter Spindle Replica Pendant Necklace In Silver Tone: Jewelry: Amazon.com
Record adapter necklace
Adina Mills
Design Green, Adina Mills, Mills Design, Gemstone Rings, Chunky Rings, Fluorit Rings, Gorgeous Rings, Green Fluorit, Stones Rings
Gemstone ring adina mills design
pretty stone ring
Love a chunky ring!
Adina Mills Design Green Fluorite Ring i like unique pieces
gorgeous ring
Johnny Cash necklace
Guns, Style, Walks The Line, Close Watches, Johnny Cash Necklaces, Jewelry, Johnny Cash Quotes, Accessories, Johnnycash
oh my Johnny Cash necklace! obsessed! gun necklace - walk the line
Johnny Cash Necklace. ☀CQ Kickin' it Southern Style
Do you keep a close watch on your heart? We all should take some advice from the Man in Black. Wear this powerful mantra close to your heart with this hand-stamped Johnny Cash Necklace. It showcases a hand-stamped brass oval with pewter gun charm — sterling silver box chain. JOHNNY CA
Country Star - Johnny Cash Quote Necklace with Pistol *cute* #jewelry #necklace #gun #fashion #pistol #quote #country
johnny cash necklace #necklace #jewelry #johnnycash
Johnny Cash gun necklace with quote "I keep a close watch on this heart of mine." $47.00 -- accessories. necklace. jewelry. chain and pendant. badass.
Reading. Always reading.
Books, Choo Reading, Hard Choice, Choose Reading, So True, Bookworm, Reading Win, Hard Decision, True Stories
Such a hard decision! (not really. I choose reading all the time)
It's not a very hard choice...
Reading wins until a drop the book and fall asleep!
.. and I almost always choose reading! So true!:)
True story. Usually reading wins
Boston Terriers
Boston Terriers Love, Pet Portraits, Boston Bull, Dogs Art, Terriers Boston Boards, Boston Terriers, Beautiful Dogs, Animal, Boston Terriers Puppies
Boston Terrier dog art portraits, photographs, information and just plain fun. Also see how artist Kline draws his dog art from only words at drawDOGS.com #drawDOGS
#Boston #terrier #puppy #photography #pets #portraits
The most beautiful dogs on the planet!
1965 Shelby GT350
Sports Cars, Shelby Gt350Sr, Muscle Cars, Ford Mustang, 1965 Shelby, Fast Cars, Mustang Gt500, Dreams Cars, Cars Photography
Ford Mustang GT500
1965 Shelby GT350SR = dream car.
Most Beautiful #Shelby #Gt350 #Car #Photography
1965 Shelby GT350SR. Classic. I just love muscle cars.
fast cars! 1965 Shelby GT350SR
1965 Shelby #celebritys sport cars #customized cars #ferrari vs lamborghini #sport cars #luxury sports cars| http://luxury-sports-cars-nikita.blogspot.com
Iphone Cases, Ali Gulec, Mariachi Prints, Art Prints, Prints 11X14, Of The, Dead, Digital Prints, Day
iphone case
Mariachi print $23.64
Mariachi Feliz dia de Los muertos
Mariachi Art Print by Ali GULEC | Society6
rock photographer Jim Marshall
Photographers Jim, Favorite Photo, Art Photography, Rocks Photographers
On of my most favorite photos of all time, by rock photographer Jim Marshall
rock photographer Jim Marshall
Concerts, The Beatles, Finals, Paul Mccartney, Sanfrancisco, Jim Marshalls, Photo, San Francisco, Candlesticks Parks
Paul McCartney shares never-seen-before photo from The Beatles' final gig at San Francisco's Candlestick Park
The Beatles (Jim Marshall, 1966) San Francisco: Marshall, the official photographer to shoot the Beatles' final live concert, captured the Fab Four -- John, George, Paul and Ringo -- heading for the stage that evening of August 29th in Candlestick Park.
sheet music illustrations by Mike Lemanski
Russian Artists, Music Inspiration, Music Iv, Drawings Art, Illustrations Drawings, Music Illustration, Music Sheet, Mike Lemanski, Sheet Music Art
Russian sheet music IV
Russian Artists Bring Sheet Music to Life
Musical Sheet Cartoons
drawing art on sheet music bringing to life by people too (12)
Juxtapoz Magazine - Sheet Music Art by Mike Lemanski
#PeopleToo | Etude 6. #illustration #drawing


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Yellowstone national park is one of the locations that you need to do is it in your lifetime. Words cannot describe how beautiful this place is.
Don't take my word for it, go...
read more
Yellowstone national park is one of the locations that you need to do is it in your lifetime. Words cannot describe how beautiful this place is.
Don't take my word for it, go and see for yourself.
Over the years the Yellowstone River has cut deep canyons with its strong
current. An upper and a lower waterfall are highlights and a must vista.
Beautiful area of Yellowstone National Park. We hiked to all of the view points and got a different view of the river and the waterfall each time from the North Rim to the South Rim. We even climbed Uncle Tom's staircase which was well worth each tiring step back up!
An absolute must see if visiting Yellowstone National Park. Take some short hikes and get away from the crowds.
The views of the Yellowstone River inside Yellowstone are completely breathtaking! While in Yellowstone be to stop and take in a view or two.
Beautiful river - very wide in some places. We saw several people fishing on the river, using waders. Watch your kiddos - some places are deep & very fast. Gorgeous veiws & a good place to see animals in the park.
Yellowstone River in Yellowstone NP is a bit of a drive, but well worth it for the view. The waterfalls are simply some of the best in the U.S. The staircase walk down to see the Lower Falls is a classic hike offering a beautiful view of the Falls. The short hike to the Upper Falls is easier and the...
Wow! Yellowstone really is nature at its best. Natural beauty everywhere you look.
Lots of driving to get from place to place, in the west side we hiked the bacon grind trail, then drove to the boiling River and stopped at gibbon falls. All this with a 3 month old.
We need to come back so much more to see!
We stopped by the bank to enjoy the scenic beauty for a moment. My husband was trying to teach the kids to skip rocks across the face of the water when, suddenly, all of our attention was drawn to jumping fish and a gorgeous cow Elk lying in the cool grass directly across the river from us. What a great....
Breathtaking, undeniably one of the most scenic parts of our great country...great rafting, fishing and just plain hiking...an absolute must experience
Register now for free — and start getting automatic notification of new reviews, responding to traveler feedback, adding new photos to your listing and much more.
We are coming in on Friday. Where do I go to hike around and see the river and meadow? Do I sign up for a tour, or will people point us in the direction to go? Thanks
See all questions

subset: commoncrawl


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Gaseous Oxygen System Servicing
Aviation Structural Mechanic E2 - How airplanes are built and how to maintain them
The following are general procedures for
servicing a high-pressure oxygen system.
Since aircraft oxygen systems vary in
design, always check the applicable MIM or
maintenance requirements card prior to servicing
an aircraft oxygen system.
1. Prior to servicing (recharging) an aircraft
gaseous oxygen system, ensure that the following
conditions exist on the aircraft and the oxygen
servicing trailer.
The trailer and aircraft should be
properly grounded.
The line valve on the oxygen servicing
hose should be closed.
All six trailer manifold control valves
should be closed.
Both pressure regulators and their
associated shutoff valves should be
All six individual cylinder valves should
be opened and the individual cylinder
pressures noted.
2. Open the cylinder valve and then the
manifold control valve on the cylinder with the
lowest pressure above the aircraft system pressure.
3. Open the two shutoff valves on each side
of the pressure regulator valve that is to be used.
(The oxygen servicing trailer is equipped with two
pressure regulators so that in the event of the
failure of one, the other maybe used.)
4. Slowly open the pressure regulator valve
(by turning the control knob clockwise) and allow
the pressure to buildup to the trailer cylinder
pressure. The set pressure of the regulator may
be noted on the regulator gauge.
A temperature connection charge is
given in the applicable MIM or on the side of the
servicing trailer. This chart is used to determine
the pressure to which the aircraft cylinders should
be filled. This pressure depends on the ambient
temperature, as maybe noted on the thermometer
on the trailer manifold stand.
5. Slowly open the service valve on the
servicing hose, and bleed the hose to ensure that
all loose foreign matter that might be within the
hose is expelled.
6. Close the service valve on the hose, and
attach a high-pressure adapter to the coupling nut
on the servicing valve.
7. Open the access panel to the aircraft
oxygen filler valve. Check the filler valve and the
area around the filler valve for any trace of oil,
grease, or any other foreign material. Clean the
area if necessary. Unscrew the dust cap from the
aircraft filler valve.
8. Connect the service hose high-pressure
adapter to the aircraft filler valve.
9. Slowly open the service valve on the hose.
When there is no longer a flow of gas (lower
manifold gauge is within 15 pounds of the
supply cylinder gauge), close the cylinder valve
and the manifold control valve, and repeat the
process with the cylinder with the next higher
pressure. Work cylinders in increasing order of
their pressure until the aircraft system pressure
has reached the desired reading.
Oxygen under high pressure will
increase in temperature during the servicing
procedure. To obtain the desired pressure in the
aircraft system, cylinders should be filled slightly
above 1,800 psi (+50 to +200 psi), depending
upon the ambient temperature.
10. After fully charging the aircraft system,
close the service hose valve, shutoff valves,
pressure regulator, and associated shutoff valves,
manifold control valves, and cylinder control
valve, in that order.
11. Disconnect the servicing hose from the air-
craft filler valve, and relieve the hose pressure by
opening the service valve on the hose.
12. Close the service valve and stow the hose
in the trailer hose basket.
13. Replace the aircraft filler valve dust cap
and the access plate.
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Hardware Drivers Software
- Status: 7 - Inactive ×
Linux Trip Computer
This program allows the user's laptop to act as a trip computer displaying fuel economy, speed, and other information about a car which is connected through a hardware device to the parallel port.1 weekly downloads
TMS320C6x development tools
The goal of the c6x-tools project is to provide an Open Source development environment for users of the TI TMS320C6x DSP family. This includes (but is not limited to) the following commonly-used devices: 'C6211, 'C6711, 'C6201 and 'C6701.1 weekly downloads
Unofficial LBP-3010 CAPT3 Solaris driver
Unofficial CAPT 3.0 driver for CUPS to support Canon LBP-3010 USB printers. I developed this driver because the official driver is only for Linux and I needed it for Solaris. I reverse engineered the CAPT3.0 protocol to develop this driver.1 weekly downloads
X36 NT Driver
A software package to use/program the Saitek X36 (gameport) joystick under Windows XP/2003/Vista/Seven 32 and 64 bit operating systems.1 weekly downloads
ZyXEL Modem Drivers for OS X/Darwin
This project should bring as much as possible ZyXEL modem drivers to Mac OS X/Darwin.1 weekly downloads
iMON PC remote Linux driver
Linux driver for Soundgraph's iMON PC infrared remote control (http://imon.soundgraph.com) This project is stopped.1 weekly downloads
ACPI for large systems
This project is dedicated for supporting large SMP and cc-NUMA platform configuration using ACPI 2.0 or later, including cc-NUMA configuration support and implementation of various module drivers for hotplug, sleep states and large I/O subsystem.0 weekly downloads
HP Scanjet 2200C USB Driver
HP Scanjet 2200C Driver for SANE - Closed because the scanner is now fully supported in the official SANE distribution.0 weekly downloads
IEEE1394 Digital Camera API
iidcapi provides a standardized interface to control an IEEE1394, IIDC compliant digital camera0 weekly downloads
This project tries to provide an interface to use the Samsung Mobile phone SGH-P200 under GNU/Linux systems.0 weekly downloads
Speech library
This library make it possible to easily access speech synthesis.0 weekly downloads
From-scratch GPL'd firmware for Razer Copperhead/MS HABU mice.0 weekly downloads


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February 7th to March 16th 2013
February 23rd 2013, from 11:00 to 19:30
February 21st to February 24th 2013
February 5th to February 23rd 2013
February 23rd 2013, from 10:00 to 17:30
January 16th to December 31st 2013
February 22nd to February 24th 2013
Hack day
February 22nd to February 23rd 2013
December 13th 2012 to February 24th 2013
December 6th 2012 to February 24th 2013
March 23rd 2011 to December 31st 2015
Know of an event we're not listing? Why not quickly add it? Add an event
Facebook has launched free voice calling as part of its iOS Messenger app in the UK »
How artist Olly Moss and developer Campo Santo illustrated the stunning national park setting of Firewatch »
N++ is the final version of a devastatingly hard freeware PC platform game, exclusive to PS4. With the game out this week, Michael Rundle returns to the glory and tragedy of an old gaming flame. »


text:
Relevant offers
The courtyard of La Mosquee De Paris is a blue-and-white wonderland, complete with mosaics, sculptures and chirping birds. A world away from the Metro strike that consumes Paris the day I visit, the mosque is instantly soothing.
Much like a Mediterranean cafe, the front terrace bar ("salon de the") is awash with the scent of freshly brewed mint tea. A glass-front display case overflows with North African treats but it is the unassuming door behind the cabinet that lures most visitors. A discreet arrow points towards the mosque's hammam and a sign on the door lets you know today is "reserve aux femmes" ladies only.
A Middle Eastern variant of the steam bath, brought to Paris by North African immigrants, hammams are age-old places of social gathering, cleansing and relaxation. The fact that this hammam is in a mosque gives it an enhanced sense of meditation and calm but the worshippers themselves never cross paths with the ladies on a pampering mission.
Built in 1927, the Hispano-Moorish mosque is architecturally spectacular. It also has a restaurant, a souk (market) overflowing with crockery and colourful fabrics and the salon de the. A mixture of tourists and locals slips through the gates but those who visit the hammam the most are Parisian to the core.
Squeezing past the dessert cabinet, I slip into a darkened anteroom with cushioned lounges against each wall. The sweet smell of rose petals and apple fills the room and another door opens to the massage parlour.
A stout woman in a long, white lab coat greets me abruptly, indicating a price list, a menu of different hammam combinations, including massage, gommage (a loofah scrub-down), mint tea and tagine. She bustles towards the counter, selects an orange loofah mitt for my personal scrubbing use and stuffs three tickets into my hand: "un the", "une gommage", "une massage 20 mins". Finally, she slips a sachet of black soap into my hand and indicates the changing rooms. She points out the hammam rooms through the steam and beyond the massage tables, marble columns and blue cushioned mats where a few women are draped, with towels wrapped around their heads and bodies, eyes closed in deep reverie.
In the locker room, a lone woman dries her hair, blissfully nude and oblivious to the new kid on the block. And herein lies the question: to be nude, semi-nude or not to be at all? I'm slightly uncomfortable waltzing into the sauna sporting a string bikini, so I settle for the topless approach and wander into the misty chambers.
In the first chamber, an ample-bodied woman is sprawled across the marble bench, lathered in a black mass of gritty soap from head to toe. She's straddling a hose, shooting water down her back and exfoliating enthusiastically as she chats to her neighbour, a woman equally lathered and frothy.
At one end of the scrubbing room is a small area with two adjacent tables, both of them covered with padded mats. Another stout woman stands guard. She's decked out in an oversized singlet and skirt and is saturated. She ushers me back into chamber one but I get lost and find myself trapped in one shower cubicle, then another, before I follow a side door into the hammam proper and the steam descends.
It's gloriously foggy and the sauna's healing mist engulfs me instantly. It takes a moment before my eyes adjust, as a small skylight above provides the only outside light.
A marble stage is raised in the centre of the room. Off to each side of the stage are partitioned platforms, also raised, with water cascading down the sides.
A plump woman squats on a platform, dipping her bucket into the water and dousing herself. She is surrounded by beauty products, from shampoo to facial cleanser, mud masks and shaving cream.
The third chamber is searingly hot. My nostrils burn as I acclimatise, seeking a space beside the plunge pool as a group of gorgeous French women shriek and splash each other with the cool water.
I slink back to the main room and lie on one of the raised marble slabs, breathing the sauna in deeply. It's a hard surface but as the steam relaxes the muscles, your body sinks in and before too long you drift away.
Soon my reverie is broken by stout woman No. 2 calling "Gommage! mademoiselle, gommage?"
She hustles me onto a table. The padded mat lining squelches beneath my wet body as she dons my orange loofah mitt and starts. This is a thorough scrub-down: there's not so much as a hint of lather to soften her voracious scouring. But the results are remarkable.
She scrapes over my breasts, scratches across my stomach and lifts my arms above my head before tearing over my armpits. She flips me over, slides my briefs down and scrubs my bottom vigorously. Layer upon layer of dead skin rolls from my body.
"Rinse. Apres massage," she barks. And I head for the showers, where I lather myself in the black soap paste and let the water wash away the dead skin cells. I venture into the cool room adjacent to the reception desk, seeking my massage salvation. Two Turkish women stand over the tables, rubbing oil into their clients, massaging their temples, breasts and toes.
I lean against a marble column, dozing off before I am again summoned. I'm basted up like a turkey dinner, dripping oil as stout woman No. 1 pummels and caresses me in rotation.
It is strangely soothing but I'm an oil slick once she's finished.
I head back to the shower for another rinse before reclaiming a sauna room slab for my steam-off finale. The oil sinks into my pores as I in turn sink into the marble. I towel off the oil residue in the locker room before enjoying the mosque's piece de resistance in the courtyard: Un the de menthe at a mosaic-covered table with little birds twittering at my shoulder.
On the Left Bank, La Mosquee (39 Rue Saint-Hilaire, phone +33143313820, see www.la-mosquee.com) is about a 10-minute walk from Ile Saint-Louis or Rue Mouffetard. The closest Metro station is Place Monge.
Opening hours: women, Monday, Wednesday, Thursday, Saturday 10am-9pm, Friday 2pm-9pm; men, Tuesday 2pm-9pm, Sunday 10am-9pm. Full body massage, gommage scrub and baths is €48 (NZ$109).
- Sun-Herald
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Bruno Barreiro Spent Thousands in Campaign Cash on Apple Computers
Like a lot of Apple fanboys, county Commissioner Bruno Barreiro recently spent big at the silicon superstore — nabbing $6,583 worth of electronics at the Lincoln Road and Dadeland Mall outlets. He also reimbursed himself $4,166 for a computer.
He didn't spend his own money on the gadgets; he dipped into his flush campaign coffers. Barreiro hasn't opened a campaign office yet, so Riptide was curious about how the political architect of Miami's most hated baseball stadium deal was using the pricey goods. Were they just personal toys?
Reached on his cell phone, Barreiro denies they're for personal use. He insists he needs top-of-the-line equipment for the August 14 primary, in which he is facing state Rep. Luis Garcia and two other poorly funded challengers. (Barreiro has raised $109,025, while his opponents have raised a combined $14,465.)
"In this day and age, campaigns are relying more and more on Internet communication and websites," Barreiro says. "That is why I made the investment in these products. Apple has better graphics and data-handling capabilities than [Windows] computers and [Android] tablets."
But Robert Jarvis, an ethics professor at Nova Southeastern University's law school, says the spending spree "raises a few eyebrows."
Adds Jarvis: "He needs to show some legitimate reason why these purchases were an appropriate expenditure."
Barreiro says he uses the iPad he bought for $960 last August 16 to collect data from voters when he is knocking on doors. As for the $3,708 MacBook Pro he purchased on February 20 and the $1,747 worth of software, supplies, and accessories, the commissioner says they are used to compile that data.
"There are applications that allow you to gather information more effectively," Barreiro says. "We have been using the computers to put together mailing lists and birthday cards for registered voters."
Barreiro adds that the $10,749 worth of electronics will help him spend less money on campaign consultants. "I'm doing a lot of things in-house."
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truck driver jobs near San Antonio, TX
Truck Driver (Tank) CDL-A, Regional/OTR
Indian River Transport- San Antonio , TX
rejuvenate. As an Indian River CDL-A tank driver you will get the pay and miles you most desire. It is time to embark on the most important journey of your life. Experienced...12 days ago from Indian River Transport
Student Truck Driver - Local Training - #1 Trucking Program
C.R. England- San Antonio , TX
offers the best program to become a cdl truck driver, full benefits, more miles, more ... fast food, or customer service to a full time truck driver while traveling the...6 days ago from C.R. England
Truck Driver - Part-TimeNEW
Army National Guard- San Antonio , TX
as a tractor-trailer, heavy truck, or bus driver. You will: * Operate all wheeled ... tuition assistance. Job training for a Truck Driver consists of 10 weeks of Basic...1 day ago from Army National Guard
CDL-A OTR Company Truck Driver
Bay & Bay Transportation- San Antonio , TX
professional drivers looking for a company truck driving job that leads to something ... of 6 months' employment And with our Driver Referral Program, you can earn even more.7 days ago from Bay & Bay Transportation
Truck Driving - CDL-A OTR Company Team
Tri-national- San Antonio , TX
CDL-A OTR TRUCK DRIVERS: NEW VOLVO TRUCKS, UNBEATABLE HOME TIME & EARNING POWER Attention ... more. We offer drivers: 2014 - 2015 Volvo Truck Fleet Weekly Pay Benefits (Health, Dental...13 days ago from Tri-National
Truck Driver-Class A CDLNEW
Mccoy's Building Supply- New Braunfels , TX
questions when not driving a delivery truck. * Follows Standard Operating ... * Has successfully completed a driver's road test or has presented a copy of his/her comme...3 days ago from McCoy's Building Supply
City Driver F/T
Averitt Express- San Antonio , TX
since you enjoy daily home time as a city driver, this is an ideal position for anyone whose roots at home go deep. **One (1) year of recent Class A tractor trailer driving...12 days ago from Averitt Express
Owner Operator (CDL-A Truck Driver)NEW
USA Truck- San Antonio , TX
USA Truck has great truck driving opportunities for Class A CDL Owner Operators, Independent Contractors & Fleet Owners. Choose your trucking routes, your earnings, your benefits,...20 hours ago from USA Truck
CDL-A Owner Operator Truck Driver with Hazmat endorsement
Central Freight Lines- Alamo Heights , TX
IF YOU ONLY KNEW WHAT CENTRAL FREIGHT CAN DO FOR YOU! Central Freight Lines offers Owner Operators weekends at home and often through the week, average yearly earnings of...14 days ago from Central Freight Lines
CDL Truck Driver Trainer - Up to $91,361 YearlyNEW
C.R. England- San Antonio , TX
C.R. England is now hiring CDL Truck Driver Trainers. Increase your miles and your money by becoming a Trainer C.R. England is the largest refrigerated transportation company in...3 days ago from C.R. England
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The groundhog may have seen his shadow, but the Museum is jumping full steam into spring with its new exhibition, Accidental Genius: Art from the Anthony Petullo Collection. Containing 200 works of modern and contemporary self-taught art from some of … Continue reading
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What's Happening at the Milwaukee Art Museum: April 4-April 11
For you baseball fans, it's Opening Day at Miller Park, so here's an obligatory-yet-enthusiastic GO BREWERS! If you missed Art in Bloom last weekend, be sure to check out the photos on the Museum's Facebook page, as well as on Chelsea Kelly's latest … Continue reading
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Art in Bloom 2011 is in full swing! Huge flower displays are being wheeled through the galleries. Floral designers are snipping, arranging, considering, and re-arranging. Hundreds of garden goodies line the gallerias. There is a gelato cart, yes, you read … Continue reading
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What's Happening at the Milwaukee Art Museum: March 28-April 3
Spring has officially arrived, and that means it is time for Art in Bloom at the Museum. This year's event runs Thursday, March 31 through Sunday, April 3 and includes old favorites and new surprises. This year's event features the … Continue reading
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My mother told me that quote when I was a teenager getting ready to head off to Seattle, to an unknown future. The only thing I knew as I entered the University of Washington was that I was going to write. 672 more words
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I arrived back in November with the plans of staying for two months. Now, here I am 8 months later, the time has finally come and it is bitter sweet. 111 more words
Why Tolerance is Important
I believe that tolerance is one of the most important things when it comes to living a life with a positive affect on others. Without any tolerance not a single person in the world would have any close friends because everyone is different. 312 more words
Back in the Saddle so to Speak
The 119th edition of Cheyenne Frontier Days is in the books and so is my 10 day hiatus from writing for this blog. I hope you enjoyed the guide to eating your way through the Daddy of em All, and thanks for making the biggest post ever on our blog as well. 219 more words
The Little Twiglet gets a Baby Shower
Baby showers can be funny things. I didn't know if I wanted one. But we were privileged to have a very pleasant baby shower thrown for us on Saturday by The Sister-in-law and her helpers. 427 more words
My health is still in recovery, but it is slow and cannot be rushed. No matter how much I want to. It has also been the reason for blogging absence. 432 more words
Handy things to know...
I'm a big fan of Pinterest. I truly believe you can find out anything you want on Pinterest and I regularly go on and have a look. 134 more words


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Kyle Weaver, who helped turn around the Washington State basketball program, was drafted Thursday by the Charlotte Bobcats in the second...
Kyle Weaver, who helped turn around the Washington State basketball program, was drafted Thursday by the Charlotte Bobcats in the second round of the NBA draft.
Weaver, a 6-foot-6 guard, was the 38th overall selection.
Weaver was the ninth of 12 Pac-10 players chosen. The others:
USC guard O.J. Mayo (No. 3, Minnesota, traded to Memphis), UCLA guard Russell Westbrook (4, Sonics), UCLA center Kevin Love (5, Memphis, traded to Minnesota), Stanford centers Brook Lopez (10, New Jersey) and Robin Lopez (15, Phoenix), Arizona guard Jerryd Bayless (11, Indiana, traded to Portland), California forward Ryan Anderson (21, New Jersey), UCLA forward Luc Richard Mbah a Moute (37, Milwaukee), Oregon guard Malik Hairston (48, Phoenix), Cal center DeVon Hardin (50, Sonics), and Oregon forward Maarty Leunen (54, Houston).
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Weaver, an all-conference player, averaged 12.2 points, 5.3 rebounds and 4.3 assists as a senior last season.
Weaver and fellow seniors Derrick Low and Robbie Cowgill led the Cougars to back-to-back NCAA tournament berths.


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Musician, Composer & Engraver
Argentina - Last active: 8 days ago - Tests: 3 - Portfolio: 6
I am a musician based in Buenos Aires, Argentina. I have 8 years of experience in music copying, arranging, composing, recording, song writing and sequencing. I have been working since my first year at college. I have a bachelors degree in Guitar Performance and have studied with some very respected and well known musicians, including Daniel Piazzolla and Mariano Sivori, both 2011 Latin Grammy Award Nominees for "best instrumental album" with Escalandrum for their album "Piazzolla plays Piazzolla" and Daniel Camelo, founder and director of Inmigrantes Big Band. I am fluent in English and Spanish (native). I have at my disposal all the means to provide professional grade products and services. My attention to detail is second to none. I'm available for any work that involves music, guitar related or not. I look forward to working with you!
Recording, Mix & Mastering Engineer, Sound Designer, Composer/Arranger
Turkey - Last active: 1 month ago - Tests: 2
I am a music Producer, Recording, Mix & Mastering Engineer, DJ, sound designer, and composer with over 5 years of professional experience doing work for Pop, Jazz, Fusion, Rock, Metal, Urban (HipHop), R&B, Electro, Dance music genres, long and short film scoring, drum and synth programming, sound design for films and games and audio restoration. I own a studio called ''iCan Studios'' where I use it for professional works. I have SSL AWS900+ mixing desk (legendary SSL G series EQ), Pro Tools HD3 system, Waves mercury bundle, lots of plugins, Summit Audio, Rupert Neve, T.C outboad fx gears. Dynaudio AIR15 5.1 monitor setup, Event Opal, Yamaha HS80, Yamaha NS10, Mixcube, Event Alp5. For mastering 3-way Genelec 1037C and PMC TB2S-A. I'm very interested in different genres and enjoy working on interesting projects also I am into sound design for other mediums (such as games, mobile apps etc.), as well as getting a broader client base for the editing, composing, mixing, and design work that I do. Services: • MIXING & MASTERING • SOUND EDITING • MUSIC PRODUCTION • POST-PRODUCTION • SURROUND MIXING • MOBILE SOUND DESIGN • AUDIO BOOK PRODUCTION • SOUNDTRACKS AND JINGLES FOR COMMERCIALS • SOUND LOGOS • SOUND DESIGN • RADIO STATION ID'S • MUSIC FOR WEBSITE • MUSIC FOR VIDEO GAMES • MUSIC FOR PODCAST • MUSIC FOR AUDIOBOOKS • RINGTONES • SOUNDTRACKS FOR SERIALS • SOUNDTRACK FOR MOVIE TRAILERS • SOUNDTRACK FOR MOVIES • MOTIVATION & PRESENTATION MUSIC FOR COMPANIES • MUSIC FOR CALL CENTER • MUSIC FOR THEATER AND BALLET • MUSIC FOR EVENT PROMOS • MUSIC FOR FASHION SHOW AND ORGANISATION
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Creative Director, Producer, Web Hero
Singapore - Last active: 4 months ago - Tests: 2 - Portfolio: 7
15 years of experience in web development, UI/UX, web marketing strategist. 8 years of experience with MySQL, PHP, CSS, HTML and Javascript. 9 years of experience in music making. 8 music awards. Very good experience with Codeigniter and Wordpress. I'm a producer, web hero, entrepreneur who loves to create new things. With a few music awards under my name, I believe in the concept of fun, ease of learning, and the balance of complicated & easy ideas. All my creative work rely on these - especially when it comes to interfaces and experience for users & customers. I code, consult, write & sing. I believe that anything worth doing, is worth over-doing. I released my debut album in Taiwan, 2010. (See: http://fb.me/jericbook) I consulted for http://Garena.com for their online shop, helped design http://Shownearby.com, and built Zion / http://DotaPod.com from scratch, a gaming platform for gamers, with 190,000 members. Fluent in English & Chinese~ 真的。 I am currently Creative Director and Producer at CLE Media Productions, Singapore/Taiwan, and I run my own Web/Audio/Video Production Studio. I look forward to working with you.
Musician-audio producer
Serbia - Last active: 08/01/2013
I have many years experience with music programs such as: Cakewalk, Nuendo, Sound Forge, Pro Tool, Garage Band, FL Studio And thousands of VST plugins, of course legal and duly paid. I worked on the production of a various genres such as house, hip-hop, dub, and my favorite metal (djent, core, death). I'm not just a producer and arranger, but also the guitar, bass, drumm and keyboard player, so you can use all of my knowledge. I'm also working and in programs such as photoshop,coreldraw for logos desing. If anyone wants to contact me I promise professional, with maximum engagement, and fast implementation of business. P.S. M.Trajic
Graphic & Web Designer
United Kingdom - Last active: 06/19/2014 - Tests: 5 - Portfolio: 26
I'm a Graphic and Web Designer based in London. I worked as a freelance and as a in-house Graphic and Web designer for STAPLES from 2007 to 2011. I'm a Mac user, passionate, quick and accurate. I love fresh and clear design. My motto is less for more.
computer scientist student
Germany - Last active: 1 day ago
- allround musician - student of Applied Informatics (Bachelor of Science) - formerly student employee (IT Development - back office) for a ~200 employees print-online-publisher
Freelance Sound Engineer
South Africa - Last active: 6 months ago - Tests: 1 - Portfolio: 8
I love my family, I love life, I love music. In 2000 I started my own project recording studio and in 2013, I closed the studio to venture in to audio post-production. In the period 2000 – 2013, I've recorded from Gospel Choirs to Hip Hop. You can say that I was involved in a wide genre spectrum. My preferred genres however are POP, ROCK and Light Classical. My primary work was recording and mixing, but I also did arrangements and produced and co-produced over 120 albums. I'm currently doing freelance work with my focus on audio post-production. Some of my latest projects were PS 4 and Durex commercials and is busy with a full length and a short film. I mainly use Pro-Tools for recording and mixing and do a lot of sequencing with Reason, but also like to use some of Pro-Tool's in-house facilities. In 1996 I graduated with a diploma in T3 Light Current Electrical Engineering, which is of huge help in understanding filters, equalization and sound as a general. I consider myself to be a loyal, committed and helpful person. One of my strengths is that I am persistent when it comes to problem solving. What started off as a hobby years ago, is now my work, and I still enjoy every minute of it. You are more than welcome to contact me for any further details. There is a saying that says "Music is what feelings sound like", and I believe that is the closes you can describe music. Regards Ettienne
- Music Arrangement
- Avid Pro Tools
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Web dev, Python specialist, team leader
Brazil - Last active: 7 days ago - Portfolio: 5
I am a systems analyst who has been specializing in Python since 2007. I am an enthusiast of the Scrum and Extreme Programming agile methodologies, having been working with these since 2010. I have been polishing my skills as a development team leader. Web frameworks? I have been using Pyramid, Flask, Google App Engine (with ndb), CherryPy, even Django. I have also been developing desktop applications in Python (with PySide / PyQt). Passionate about open source, I develop on Ubuntu Linux. Everyone should know why Python is important. Hey, let me tell you that right now. Python is so good because it is the most readable language available. It reads almost like English. Code is read more often than it is written; making sense of code is what a programmer does most of the time. Of course Python has other strong points -- it is very expressive and reflective -- but readability is the most important thing. As a native Brazilian, I can write perfectly in Portuguese. I also speak English fluently, having scored 106/120 on TOEFL IBT. I am a perfectionist -- a developer who loves Python and always delivers quality, documented, highly readable code. I write well-factored object-oriented code that is compatible with both Python 2 and Python 3. I have a keen interest in software architecture and I am familiar with MVC, 3-tier, design patterns, localization and internationalization. I possess profound knowledge of web standards such as HTML 5, XHTML, CSS, Javascript, AJAX, JSON, tableless design, HTTP, REST, MIME... I also know a lot about Python libraries such as SQLAlchemy, Babel, Celery, Deform, Colander, BeautifulSoup, PyParsing, Celery, a few templating languages (Kajiki, Genshi, Chameleon, Jinja2 etc.) I have been using bootstrap and AngularJS in latest projects. I am an advanced user of both git and hg (Mercurial). If you know Python you can see I am good in this language by taking a look at my github: - https://github.com/nandoflorestan Here are my most important open source projects: - https://pypi.python.org/pypi/releaser - https://pypi.python.org/pypi/Kajiki - https://pypi.python.org/pypi/nine - https://pypi.python.org/pypi/bag - https://pypi.python.org/pypi/deform_bootstrap_extra - https://pypi.python.org/pypi/poorbox - http://sourceforge.net/projects/backalaika/ Before discovering Python, I worked with C# for 4 years. Back then I wrote a recursive MIME parser in C#: - http://sourceforge.net/projects/nandof/ You can expect for your project this kind of clarity, readability and passion! Please note I won't use Upwork Hourly Protection because I think taking screenshots of my computer is too invasive.
- System Programming
- Python
- JavaScript
- AngularJS
- Git
- Management Skills
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Associated with: Oui Software
Xaman Tech Developer
Mexico - Last active: 1 day ago - Tests: 1
I am a Web developer with experience in various technologies such as Adobe Flash and HTML5. I have developed several projects in the area of causal games. Complement my services with long experience in multimedia, editing: audio, video and image. Also professional musician and music for games. Specialist MiklyTracker, music for Unity3D In my experience, ***good communication and punctuality*** are the basis for a successful project. Warmly will attend any questions ;-)
Versatile Full Stack Web Developer
France - Last active: 4 days ago - Tests: 10 - Portfolio: 6
I am a "versatile" full stack web developer. I can perform those tasks (in order of proficiency): - web development and integration (phpMysql, html5/css3, ajax) - network, system and web server administration (git/ssh, apache2, nGinx) - domain names and web hosting management - psd to htm conversion I mainly know how to use 4 services of AWS: - EC2 - S3 (which I generally use to store photos for instance) - How to create IAM roles linked to an EC2 instance to communicate and interacting with s3 content (My website for instance use aws php sdk to display photos from my s3 bucket) - I know about cloudfront (and use geographic restriction on my website also) - I already made route 53 configurations My methods of code deployment, backup and maintenance are fast and safe since I will have a git repo of your project on bitbucket, locally on my machine and preferably on a compute cloud service (AWS). My speed inet connection is 5mbs. ps: sorry I am not interested in working with social network API.


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The Jewish Network
The Social Network meta reviews
By: Culture Staff
The most talked about movie since Avatar is being released this week and it couldn't be any more Jewish. The Social Network, based on the book The Accidental Billionaires by Ben Mezrich, is the story of the early beginning of Faceook, the largest social media site in the world.
The movie's written by Aaron Sorkin, the veteran television writer whose credits include the West Wing and the upcoming Brad Pitt feature, Moneyball and directed by David Fincher, of Fight Club fame. Playing Facebook's founder, Mark Zuckerberg is Jesse Eisenberg, whose recently released movie Holly Rollers introduced audiences to drug dealing Hasidic Jews.
So we have a Jewish book author, Jewish film author, Jewish director and a Jewish actor playing a Jewish hero. This would usually either lead to a Woody Allen movie, of which none have been good in recent years, or a Coen Brothers movie, which would put most audiences to sleep.
However, the consensus here is that The Social Network is one of the best movies of the year. Here are snippets of some early reviews:
"Smartly written by Aaron Sorkin, directed to within an inch of its life by David Fincher and anchored by a perfectly pitched performance by Jesse Eisenberg, The Social Network is a barn-burner of a tale that unfolds at a splendid clip" – Kenneth Turan: Los Angeles Times
"The social Network has everything you want in a thriller for the brain: huge doses of ego and duplicity, corporate backstabbing, and some very layered performances." – Owen Gleiberman: Entertainment Weekly
"Brilliantly directed by David Fincher, this provocative film probes the impetus for invention, the changing face of social interaction and the limits of friendship – the old-fashioned kind and the version linking 500 million Facebook users" – Caludia Puig: USA Today
"David Fincher's film has the rare quality of being not only as smart as its brilliant hero, but in the same way. It is cocksure, impatient, cold, exciting and instinctively perceptive." – Roger Ebert: Chicago Sun-Times
The Social Network opens in theaters nationwide on Friday, Oct 1st, 2010.
Anti-Violence Rallies Taking Place Across Israel TodayAugust 01, 2015 | By Noam 'Dabul' Dvir, Roi Yanovsky, Ahiya Raved, and Gilad Morag
Following two blood-soaked days, in which a Palestinian infant was killed and his parents and sibling were critically wounded in a fire and six people were hurt in a stabbing at Jerusalem's gay pride parade, thousands are expected to protest in Tel Aviv, Jerusalem, and Haifa
Report: 53% Rise in Anti-Semitic Incidents in the UKAugust 01, 2015 | By B. Shane Morganstein
Government officials are speaking out against anti-Semitism after new report finds rapid increase in anti-Semitic incidents
Film to be Made about Jonathan PollardAugust 01, 2015 | By B. Shane Morganstein
The American jailed for passing sensitive information to Israel will have his story adapted for the big screen
Over 100 Jewish Gravestones Toppled in PhiladelphiaAugust 01, 2015 | By Maria Cruz
Some of the headstones date back 160 years
Woody Allen Speaks Out About NetanyahuAugust 01, 2015 | By Maria Cruz
The director thinks the Prime Minister's decision on Iran deal could be "foolish"
WATCH: Jon Stewart Addresses Uproar over his "Secret" Meeting with President ObamaJuly 30, 2015 | By Daina Goldfinger
"Something is not a secret just because you don't know about it"
Canadian Couple: Killing Young Jews Will Save Them from HellJuly 30, 2015 | By B. Shane Morganstein
The couple, convicted of trying to bomb the British Columbia Legislature, hoped to save Jews from growing up and going to "eternal hell"
WATCH: Viral Video of Israeli Father Shaving his Beard for First Time in 14 YearsJuly 30, 2015 | By B. Shane Morganstein
People are going crazy for this family's reaction to a man named Mooki shaving his beard
The Ten Most Famous Jewish Porn Stars Culture » Society » News


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U.S. Marine Corps Ceramic Travel Mug
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Semper fi! The Marine Corps motto resonates down through the generations and throughout the world. A Marine is always faithful, and proud of it. Our ceramic travel mug pays tribute to these American heroes.
- Dolomite ceramic
- Acrylic, twist-lock lid
- 6.25" T x 2.5" dia (17.8 x 8.3 cm)
- Holds 16 fl. oz. (473 ml)
- Made in China
For bulk pricing on these and other items, please contact our Customer Service department at email@example.com.
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Recent reviews:
January 2, 2014 - Bought this for my husband for Christmas he loves it, but the lid doesn't fit properly I called and they are sending me a new one,very good customer service.
December 24, 2012 - every thing i thought
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Building on widespread use of the C++ programming language in industry and education, this book provides a broad-based and case-driven study of data structures -- and the algorithms associated with them -- using C++ as the language of implementation.
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The premier destination for delicious pizza, Hope General Store in Hope is one of the area's top-rated restaurants. It's an ideal choice for visitors looking for good food.
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NAR Top Articles - RNA
June 2015
Predominance of spliceosomal complex formation over polyadenylation site selection in TDP-43 autoregulation
Bembich, S; Herzog, JS; De Conti, L; Stuani, C; Avendano-Vazquez, SE; Buratti, E; Baralle, M; Baralle, FE
Nucleic Acids Res. 2014, 42, 3362-3371
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TDP-43 is a nuclear protein involved in many aspects of RNA metabolism. To ensure cellular viability, its expression levels within cells must be tightly regulated. We have previously demonstrated that TDP-43 autoregulation occurs through the activation of a normally silent intron in its 3'-UTR sequence that results in the use of alternative polyadenylation sites. In this work, we analyse which is the dominant event in autoregulation: the recognition of the splice sites of 3'-UTR intron 7 or the intrinsic quality of the alternative polyadenylation sites. A panel of minigene constructs was tested for autoregulation functionality, protein production and subcellular messenger RNA localization. Our data clearly indicate that constitutive spliceosome complex formation across intron 7 does not lead to high protein production but, on the contrary, to lower TDP-43 messenger RNA and protein levels. This is due to altered nucleocytoplasmic distribution of the RNA that is mostly retained in the nucleus and degraded. This study provides a novel in-depth characterization of how RNA binding proteins can autoregulate their own levels...
Translation rate is controlled by coupled trade-offs between site accessibility, selective RNA unfolding and sliding at upstream standby sites
Borujeni, AE; Channarasappa, AS; Salis, HM
Nucleic Acids Res. 2014, 42, 2646-2659
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The ribosome's interactions with mRNA govern its translation rate and the effects of post-transcriptional regulation. Long, structured 5' untranslated regions (5' UTRs) are commonly found in bacterial mRNAs, though the physical mechanisms that determine how the ribosome binds these upstream regions remain poorly defined. Here, we systematically investigate the ribosome's interactions with structured standby sites, upstream of Shine-Dalgarno sequences, and show that these interactions can modulate translation initiation rates by over 100-fold. We find that an mRNA's translation initiation rate is controlled by the amount of single-stranded surface area, the partial unfolding of RNA structures to minimize the ribosome's binding free energy penalty, the absence of cooperative binding and the potential for ribosomal sliding. We develop a biophysical model employing thermodynamic first principles and a four-parameter free energy model to accurately predict the ribosome's translation initiation rates for 136 synthetic 5' UTRs with large structures, diverse shapes and multiple standby site modules...
Negative regulation of the interferon response by an interferon-induced long non-coding RNA
Kambara, H; Niazi, F; Kostadinova, L; Moonka, DK; Siegel, CT; Post, AB; Carnero, E; Barriocanal, M; Fortes, P; Anthony, DD; Valadkhan, S
Nucleic Acids Res. 2014, 42, 10668-10680
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Long non-coding RNAs (lncRNAs) play critical roles in diverse cellular processes; however, their involvement in many critical aspects of the immune response including the interferon (IFN) response remains poorly understood. To address this gap, we compared the global gene expression pattern of primary human hepatocytes before and at three time points after treatment with IFN-alpha. Among similar to 200 IFN-induced lncRNAs, one transcript showed similar to 100-fold induction. This RNA, which we named lncRNA-CMPK2, was a spliced, polyadenylated nuclear transcript that was induced by IFN in diverse cell types from human and mouse. Similar to protein-coding IFN-stimulated genes (ISGs), its induction was dependent on JAK-STAT signaling. Intriguingly, knockdown of lncRNA-CMPK2 resulted in a marked reduction in HCV replication in IFN-stimulated hepatocytes, suggesting that it could affect the antiviral role of IFN. We could show that lncRNA-CMPK2 knockdown resulted in upregulation of several protein-coding antiviral ISGs...
A dynamic alternative splicing program regulates gene expression during terminal erythropoiesis
Pimentel, H; Parra, M; Gee, S; Ghanem, D; An, XL; Li, J; Mohandas, N; Pachter, L; Conboy, JG
Nucleic Acids Res. 2014, 42, 4031-4042
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Alternative pre-messenger RNA splicing remodels the human transcriptome in a spatiotemporal manner during normal development and differentiation. Here we explored the landscape of transcript diversity in the erythroid lineage by RNA-seq analysis of five highly purified populations of morphologically distinct human erythroblasts, representing the last four cell divisions before enucleation. In this unique differentiation system, we found evidence of an extensive and dynamic alternative splicing program encompassing genes with many diverse functions. Alternative splicing was particularly enriched in genes controlling cell cycle, organelle organization, chromatin function and RNA processing. Many alternative exons exhibited differentiation-associated switches in splicing efficiency, mostly in late-stage polychromatophilic and orthochromatophilic erythroblasts, in concert with extensive cellular remodeling that precedes enucleation. A subset of alternative splicing switches introduces premature translation termination codons into selected transcripts in a differentiation stage-specific manner...
Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions
Vojtech, L; Woo, S; Hughes, S; Levy, C; Ballweber, L; Sauteraud, RP; Strobl, J; Westerberg, K; Gottardo, R; Tewari, M; Hladik, F
Nucleic Acids Res. 2014, 42, 7290-7304
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Semen contains relatively ill-defined regulatory components that likely aid fertilization, but which could also interfere with defense against infection. Each ejaculate contains trillions of exosomes, membrane-enclosed subcellular microvesicles, which have immunosuppressive effects on cells important in the genital mucosa. Exosomes in general are believed to mediate inter-cellular communication, possibly by transferring small RNA molecules. We found that seminal exosome (SE) preparations contain a substantial amount of RNA from 20 to 100 nucleotides (nts) in length. We sequenced 20-40 and 40-100 nt fractions of SE RNA separately from six semen donors. We found various classes of small non-coding RNA, including microRNA (21.7% of the RNA in the 20-40 nt fraction) as well as abundant Y RNAs and tRNAs present in both fractions. Specific RNAs were consistently present in all donors. For example, 10 (of similar to 2600 known) microRNAs constituted over 40% of mature microRNA in SE. Additionally, tRNA fragments were strongly enriched for 5'-ends of 18-19 or 30-34 nts in length...
Interplay between pre-mRNA splicing and microRNA biogenesis within the supraspliceosome
Agranat-Tamir, L; Shomron, N; Sperling, J; Sperling, R
Nucleic Acids Res. 2014, 42, 4640-4651
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MicroRNAs (miRNAs) are central regulators of gene expression, and a large fraction of them are encoded in introns of RNA polymerase II transcripts. Thus, the biogenesis of intronic miRNAs by the microprocessor and the splicing of their host introns by the spliceosome require coordination between these processing events. This cross-talk is addressed here. We show that key microprocessor proteins Drosha and DGCR8 as well as pre-miRNAs cosediment with supraspliceosomes, where nuclear posttranscriptional processing is executed. We further show that inhibition of splicing increases miRNAs expression, whereas knock-down of Drosha increases splicing. We identified a novel splicing event in intron 13 of MCM7, where the miR-106b-25 cluster is located. The unique splice isoform includes a hosted pre-miRNA in the extended exon and excludes its processing. This indicates a possible mechanism of altering the levels of different miRNAs originating from the same transcript. Altogether, our study indicates interplay between the splicing and microprocessor machineries within a supraspliceosome context.
A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs
Suzuki, T; Suzuki, T
Nucleic Acids Res. 2014, 42, 7346-7357
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In mammalian mitochondria, 22 species of tRNAs encoded in mitochondrial DNA play crucial roles in the translation of 13 essential subunits of the respiratory chain complexes involved in oxidative phosphorylation. Following transcription, mitochondrial tRNAs are modified by nuclear-encoded tRNA-modifying enzymes. These modifications are required for the proper functioning of mitochondrial tRNAs (mt tRNAs), and the absence of these modifications can cause pathological consequences. To date, however, the information available about these modifications has been incomplete. To address this issue, we isolated all 22 species of mt tRNAs from bovine liver and comprehensively determined the post-transcriptional modifications in each tRNA by mass spectrometry. Here, we describe the primary structures with post-transcriptional modifications of seven species of mt tRNAs which were previously uncharacterized, and provide revised information regarding base modifications in five other mt tRNAs. In the complete set of bovine mt tRNAs, we found 15 species of modified nucleosides at 118 positions (7.48% of total bases). This result provides insight into the molecular mechanisms underlying the decoding system in mammalian mitochondria...
Phosphorothioate oligonucleotides can displace NEAT1 RNA and form nuclear paraspeckle-like structures
Shen, W; Liang, XH; Crooke, ST
Nucleic Acids Res. 2014, 42, 8648-8662
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Nuclear paraspeckles are built co-transcriptionally around a long non-coding RNA, NEAT1. Here we report that transfected 20-mer phosphorothioate-modified (PS) antisense oligonucleotides (ASOs) can recruit paraspeckle proteins to form morphologically normal and apparently functional paraspeckle-like structures containing no NEAT1 RNA. PS-ASOs can associate with paraspeckle proteins, including P54nrb, PSF, PSPC1 and hnRNPK. NEAT1 RNA can be displaced by transfected PS-ASO from paraspeckles and rapidly degraded. Co-localization of PS-ASOs with P54nrb was observed in canonical NEAT1-containing paraspeckles, in perinucleolar caps upon transcriptional inhibition, and importantly, in paraspeckle-like or filament structures lacking NEAT1 RNA. The induced formation of paraspeckle-like and filament structures occurred in mouse embryonic stem cells expressing little or no NEAT1 RNA, suggesting that PS-ASOs can serve as seeding molecules to assemble paraspeckle-like foci in the absence of NEAT1 RNA. Moreover, CTN, an RNA reported to be functionally retained in paraspeckles, was also observed to localize to paraspeckle-like structures, implying that paraspeckle-like structures assembled on PS-ASOs are functional...
Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules
Bounedjah, O; Desforges, B; Wu, TD; Pioche-Durieu, C; Marco, S; Hamon, L; Curmi, PA; Guerquin-Kern, JL; Pietrement, O; Pastre, D
Nucleic Acids Res. 2014, 42, 8678-8691
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The sequence of events leading to stress granule assembly in stressed cells remains elusive. We show here, using isotope labeling and ion microprobe, that proportionally more RNA than proteins are present in stress granules than in surrounding cytoplasm. We further demonstrate that the delivery of single strand polynucleotides, mRNA and ssDNA, to the cytoplasm can trigger stress granule assembly. On the other hand, increasing the cytoplasmic level of mRNA-binding proteins like YB-1 can directly prevent the aggregation of mRNA by forming isolated mRNPs, as evidenced by atomic force microscopy. Interestingly, we also discovered that enucleated cells do form stress granules, demonstrating that the translocation to the cytoplasm of nuclear prion-like RNA-binding proteins like TIA-1 is dispensable for stress granule assembly. The results lead to an alternative view on stress granule formation based on the following sequence of events: after the massive dissociation of polysomes during stress, mRNA-stabilizing proteins like YB-1 are outnumbered by the burst of nonpolysomal mRNA...
Cytoplasmic and nuclear quality control and turnover of single-stranded RNA modulate post-transcriptional gene silencing in plants
Moreno, AB; de Alba, AEM; Bardou, F; Crespi, MD; Vaucheret, H; Maizel, A; Mallory, AC
Nucleic Acids Res. 2013, 41, 4699-4708
Free Full Text
Eukaryotic RNA quality control (RQC) uses both endonucleolytic and exonucleolytic degradation to eliminate dysfunctional RNAs. In addition, endogenous and exogenous RNAs are degraded through post-transcriptional gene silencing (PTGS), which is triggered by the production of double-stranded (ds)RNAs and proceeds through short-interfering (si)RNA-directed ARGONAUTE-mediated endonucleolytic cleavage. Compromising cytoplasmic or nuclear 5'-3' exoribonuclease function enhances sense-transgene (S)-PTGS in Arabidopsis, suggesting that these pathways compete for similar RNA substrates. Here, we show that impairing nonsense-mediated decay, deadenylation or exosome activity enhanced S-PTGS, which requires host RNA-dependent RNA polymerase 6 (RDR6/SGS2/SDE1) and SUPPRESSOR OF GENE SILENCING 3 (SGS3) for the transformation of single-stranded RNA into dsRNA to trigger PTGS. However, these RQC mutations had no effect on inverted-repeat-PTGS, which directly produces hairpin dsRNA through transcription. Moreover, we show that these RQC factors are nuclear and cytoplasmic and are found in two RNA degradation foci in the cytoplasm...
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$3.99Holiness is one word frequently used to describe the process of drawing closer to God and away from one's natural inclination to sin. This book is intended to provoke thought and to use illustrations from farming and fishing because they were familiar to His hearers. Holiness is a vital subject for anyone who seeks fellowship with Jesus Christ but is subject that may avoid. To some the very
$3.99The Bible warns that everyone who does not believe will learn with a shudder that God is indeed angry. The next realization will be that it's personal, that God is angry with me. By then it will be too late. I seek through the Holy Spirit to introduce you to the ramifications of biblical truth to your personal eternity. This is universal to all people of any era, any race or color, any language,
$3.99Marriage is under assault in most of the world. In the Western world the idea of God as Creator is largely scorned and rejected in intellectual circles. It is then logical for these intellectuals to attack marriage as well because marriage was the first institution that God created. It precedes any form of human government. Now we see some of the results of the assault on marriage. Children suffer
$3.99We know neither the day nor the hour when the Lord Jesus will return, but only that His return is certain. Lying to oneself and to others is also a salient sin of the last days. Already we can see across cultures an avoidance of the Holy Spirit, Who is called the Spirit of Truth in John 15:26. This is reflected in the avoidance of the Holy Bible, the written Word of Truth. It is also reflected in
$3.99Why the title Fight to the Finish? It would be more pleasant and more popular to write of love and peace than of spiritual warfare. Indeed, inner love and peace is a part of the Christian life, and eventually, we will enjoy everlasting love and peace. But there is war ahead before there will be peace. In September 1938, Prime Minister Chamberlain of England claimed that he had negotiated with
$8.69Biblical history and the shorter prophets have lessons for twenty-first century Christians that are too often missed in regular study. Of Kings, Prophets, Families, and the King of Kings examines these often-neglected Scriptures, using various techniques to tell these truths in modern forms for modern times. The historical books and the shorter prophets contain critical teaching concerning human
How Faith Can Help You Win the RaceGod does not give everyone the same race to run. While some are asked to train harder or longer than others, this should be no cause for complaint. God prepares challenges for each individual, and the harder and more intense the training, the greater the ultimate prize. Draw upon real examples from the Bible and modern history in this inspirational guidebook. Youll discover:Why endurance is
$8.69The Holy Scriptures provide a compass to guide us through life. In Warnings of a Watchman, author Thomas Logie calls our attention to the keys in experiencing family joy on earth and eternal joy in heaven by obeying the words written in the Scriptures. Born spiritually dead and a sinner, Logie was changed by God's mercy, and that mercy has prepared him to communicate the Biblical views and
Come Out of Her My People: Persecution BeginsThe Christian Church of America is under attack. The explosive tinderbox of hatred towards Christians by the immoral majority is beginning to ignite. And the persecution of the saints is the final prophecy that will substantiate the assumption that America is the Great Harlot of Revelation.This 2013 Edition includes the complete Fourth Edition of "Come Out of Her My People", as well as "The Last
Understanding Bible Prophecy for YourselfTim LaHaye's bestselling book (more than 110,000 copies sold) has been redesigned to make its content even more accessible to readers and updated to include timely information relevant to biblical prophecy and current events.This easy-to-follow guide offers the tools believers need to accurately interpret biblical prophecy. Includes:solid guidelines for accurately interpreting Bible prophecycharts
The Message of the Old Testament (Foreword by Graeme Goldsworthy)The Old Testament is the story of God's promises to his people. Below its somewhat obscure surface is hidden magnificent truth about the love and power of God. Throughout its pages the reader can find promise after promise from God, all of which are fulfilled in the New Testament-in the incarnation of Jesus Christ. Author Mark Dever introduces readers to the Old Testament as a glorious whole so
$5.39You or someone you know is divorcing, and you've been taught it is a sin. What do you do? The common reaction is avoidance or judgment, especially toward the one initiating a divorce. A change in this attitude is long overdue. The Bill of Divorcement in Bible times represented a clean break between partners who would otherwise be locked in a lifetime of misery, neglect, or abuse. Its original


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Pernilla August
- Birthday
- Feb 13, 1958
A favorite of famed director Ingmar Bergman, Swedish actress Pernilla August has an earthy radiance and formidable talent that translated well from stage to screen when she made a lasting impression in Bergman's directorial swan song, Fanny and Alexander (1982). In the years that followed, August would prove devastating with an award-winning role in the… More Bio:
A favorite of famed director Ingmar Bergman, Swedish actress Pernilla August has an earthy radiance and formidable talent that translated well from stage to screen when she made a lasting impression in Bergman's directorial swan song, Fanny and Alexander (1982). In the years that followed, August would prove devastating with an award-winning role in the Bergman-penned drama The Best Intentions before gaining international recognition with appearances in such popular mainstream American efforts as Star Wars: Episode I -- The Phantom Menace. Though the majority of her foreign roles may have gone unseen by stateside audiences, her reputation as a notable screen talent found August in constant demand overseas.
It was while performing on-stage as a young girl that August first realized the power that a talented actress could wield, and after that epiphany, there was little doubt as to the path she would pursue in life. Spending several years on Swedish television allowed August to develop her onscreen acting skills into something truly special, and after breaking into film in the early '80s, the emerging actress married author Klas Östergren. Alternating between stage and screen in the following years, August's moving performance as Bergman's mother in Bille August's The Best Intentions earned her a Best Actress award at the 1992 Cannes Film Festival, and found her separating from her first husband to marry director August. Her ensuing pregnancy may have prevented Pernilla from appearing in her second husband's 1993 film, The House of the Spirits, though she did act under his direction once again in 1996's Jerusalem before the dissolve of their five-year union. August once again summoned the spirit of Bergman's mother for the 1996 Liv Ullmann telefilm Private Confessions (again penned by Bergman), and her role in the following year's In the Presence of a Clown found her continuing to explore the persona. Despite becoming a familiar face to American audiences with her role in Star Wars: Episode I -- The Phantom Menace and Star Wars: Episode II -- Attack of the Clones, August remained faithful to her Swedish roots with appearances in such efforts as 2004's Dag och natt.
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We recently went on a cruise and hired Ephesus shuttle to provide a guide. They provided a car and driver for us to visit Ephesus and bodrum. The guide, Emre, was absolutely...
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We recently went on a cruise and hired Ephesus shuttle to provide a guide. They provided a car and driver for us to visit Ephesus and bodrum. The guide, Emre, was absolutely fantastic. He was very knowledgeable and made both tours fun and exciting. He took us to the house of the Virgin Mary, the ruins at Ephesus and the...
HIGHLY RECOMMEND!! Ephesus was a stop on our recent cruise. Arzu was an amazing, English was very well spoken and she was extremely energetic!! We arrived at the port she was waiting for the four of us with a sign with our name on it. Our two teenagers both fifteen and nineteen enjoyed the entire day! It was amazing! The...
I love experiancing history, walking in the steps of our ancestors and Ephesus is a very worthwhile trip to take if you like history. The buildings or there remains are magnificant today, I can only imagion what they looked like when they were first built. These people were ahead of their years. A must see!
We travel quite a bit and have seen quite a few ruins, but this one is on our top 10 list!
So much to see here and it's a huge site. I'm glad we had a tour guide with Tayf Tours explaining the history about everything
I would highly recommend this company. We had an excellent day in Ephesus and other sites nearby. We were a family group of mixed needs and ages, including some wheelchair use, though not all parts were accessible. Very helpful and informative, with a good sense of humour.
Fantastic trip and well worth the money. The guide Nazmi from Priene was excellent and his knowledge of the area made for a very informative day. I would recommend the tours as they are about half the price of the cruise ships' own tours! The coach driver even provided free water throughout, which was totally unexpected. Worth a big tip...
Excellent experience of ancient Roman history. The site is still under exploration and has lot of things to be seen.
This review is a year late coming but they were so unbelievably good, I felt really strongly about finally posting a review. Right from the first contact, they were prompt, friendly and helpful in answering all of my questions. I booked online and was surprized how simple and inexpensive it was to have a tour guide AND driver for a...
Brilliant half day trip. Such as amazing trip back in time. Can get a little hot and not much shade. Take water and a good pair of shoes!
I went with the organized tour through Sunway. We enjoyed it and the guide was excellent. There was just the right amount of time to walk around, do the tour with the guide and buy a few souvineers or have a snack. I found the stop at the jewellery store en route back a little annoying. The stuff is overpriced...
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WE are in Kusadasi on emarld princess on wed 20th may 2015,we dock at 8am.can you advse us on yor trips to ephesus and return to ship.ship leaves at 5pm.need to know times and prices.Thankyou Jane
We are trying to decide on a group tour versus private tour. How many people average the group tour?
How do you book ephesus shuttle
I would like to know what is the best private excursion company to use, also how much is the cost for a party of 4 taking in Ephesus, Virgin Mary and the Terrace houses tour? Two of our party are travelling from the United States to the UK and travelling with us on a cruise departing early September and I would really like them to see the best of our Kusadassi visit. Many thanks
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