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Tuesday, 20 Jul 2010 06:58 AM
Lindsay Lohan is due back in court Tuesday morning to surrender for a 90-day jail sentence that is likely to be whittled down by overcrowding and other credits.
Her stay will be longer than the 84 minutes she spent at a suburban Los Angeles jail in 2006 and marks the beginning of a new phase of punishment for drug and alcohol cases filed that year.
Los Angeles Superior Court Judge Marsha Revel sentenced the "Mean Girls" star to jail, three months in rehab and increased scrutiny by probation officials on July 6 after determining the actress violated her probation by missing seven alcohol education classes since December.
Lohan, 24, burst into tears after hearing the sentence, which came after she tearfully apologized to the judge for not strictly following the terms of her probation.
On Friday celebrity attorney Robert Shapiro signed on to the case after Lohan moved into a sober living facility that he founded. By Monday night, the Los Angeles Times and celebrity website TMZ.com, citing anonymous sources, reported that Shapiro had resigned from the case.
Shapiro met with Revel in a closed meeting late Monday afternoon. The prosecutor handling the case, Danette Meyers, was not present and court officials said there had been no change in requirements for Lohan's surrender.
In an e-mail to The Associated Press sent Monday evening after the meeting, Shapiro said his only comments would be made in open court.
Lohan, a prolific user of the microblogging site Twitter, posted a message roughly 12 hours before her court appearance referencing her looming incarceration.
"The only 'bookings' that I'm familiar with are Disney Films, never thought that I'd be 'booking' into jail eeeks," Lohan posted.
The jail and rehab stints have left some of the actress' projects in limbo, including her planned portrayal of porn star Linda Lovelace in a biopic.
Once considered an up-and-coming star, Lohan has in recent years been better-known as a tabloid staple and for the criminal case she has struggled to put behind her.
Her probation had to be extended for a year to give Lohan more time to complete her alcohol education courses and Revel ordered weekly attendance in December.
But the actress didn't complete the sessions as ordered and missed a court date in May, setting a stage for her return to jail. She is expected to serve her time — probably a quarter of her sentence or less — in isolation at a women's jail in the industrial suburb of Lynwood.
The facility has hosted several female celebrities, including Paris Hilton, Nicole Richie, Michelle Rodriguez, Khloe Kardashian and very briefly, Lohan.
© Copyright 2015 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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text: Hayley Williams Engaged? By Sammie DeanWashingtonLast updated on July 31, 2015TranslationsFrançaisEspañolDeutschItalianoPortuguês中文 Tweeter Did the 26-year-old singer just get engaged?Hayley Williams »See more news, pictures and video. Hot newsBabies July 29, 2015Hayley Williams Pregnant?Money July 30, 2015Hayley Williams is Highest-Paid Singer in the WorldOn Wednesday morning (July 29, 2015) the American Sun-Times reported Hayley Williams and boyfriend, to be shopping for engagement rings.The couple was seen closely eyeing some pricey bling in a couple of major jewelry stores — especially major diamond baubles that could only be described as the kind usually slipped on a woman's left-hand ring finger.UPDATE 31/07/2015 : This story seems to be false. (read more)According to some insiders, they'll soon be engaged.The newspaper also added that people who claim to be close to the couple are "convinced" an engagement is inevitable. "She's madly in love with him," says a source. It is believed the relationship is "heating up".Rumor Explodes on TwitterNaturally, the Sun-Times' article sent Facebook and Twitter into a frenzy. Fans were simultaneously mourning and celebrating the news. "So many people would flip but if the couple at some point announced they were engaged I'd be happy," tweeted one fan. "They're so cute!". Many other fans were crushed because they hoped to marry her...On Thursday, Hayley Williams's rep said "no comment" when asked whether the 26-year-old singer was tying the knot.Has the Sun-Times started a crazy false rumor?© 2015 MediaMass All rights reserved. Do not reproduce (even with permission).Hayley Williams: Recent NewsPets July 25, 2015Hayley Williams's Dog Recovering from SurgeryMusic July 2015Hayley Williams: New Album and 2016 World Tour?International July 31, 2015Hayley Williams, Time's 'Person of the Year' 2015?Celebrity CentralABCDEFGHIJKLMNOPQRSTUVWXYZ

subset: commoncrawl


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From checkin to checkout, we had a fantastic stay. Friendly staff, great breakfast, the coffee is always fresh and the rooms are immaculate. They even have an evening reception on some evenings. I couldn't ask for a better home away from home.
Had a wonderful stay at the Hampton Inn Chambersburg. Rooms were clean, beds comfortable. Quiet even though the hotel is right next to the interstate. Adequate continental breakfast. Would definitely recommend this hotel.
Visited Gettysburg two days. Easy drive. We went early and were able to beat the summer crowds.
Many restaurants close by- Bob Evans, Cracker Barrel, Applebee's, Texas...
Once again, Hampton differentiates their brand by being a cut above their competitors. Rooms are great, breakfast is above par, and staff are knowledgeable and friendly. Wi-fi is fast too. Pricing here is more competitive than other locations along this Interstate
Wow! We really appreciate your review. We want our guests' stay to be as comfortable as possible.
Thank you for choosing to stay with us.
We spent 3 nights at this Hampton Inn and have stayed at Hampton's Inns 4-8 times a year (and stay at hotels 4-6 times per month). This one was very disappointing. First, our non-smoking room smelled of stale smoke. Second, the walls are paper thin and you hear the blinds raising/lowering. , voices, etc. in adjacent rooms like they are...
We apologize that you did not prefer our hotel. We're very sorry that you encountered these issues while staying with us. I'm happy to see that we did extend the 100% Satisfaction Guarantee. We hope that you will continue to choose Hampton.
The hotel staff is both friendly and professional striving to meet the needs of guests. The properly is clean and well maintained. I could not imagine a more accommodating atmosphere. The staff was very flexible, providing a breakfast-to-go for u since we needed to report to work very early in the morning.
Review collected in partnership with Hampton
It is a pleasure for us to have such guests! Thank you for choosing to stay with us.
Had a room on the top floor--clean, airy, and everything for a good night's sleep while on the road. The staff were so personable and accommodating. I could not say enough wonderful things about our stay. Should we stay in the area for more than a drive through, I would definitely stay here!
Thank you for taking your valuable time to place a review! We love what we do. We hope you will continue to choose Hampton.
Great hotel experience - clean comfortable rooms, beds were really comfy, room was decorated nicely, temperature of room was easy to control and adjust, good breakfast with lots of selections, good price. Front desk was very helpful and friendly. Easy to get to from interstate. Will definitely stay here again
What a nice review. Thank you. Our guest's feedback is very important to us.
This is the perfect place to stop for a family traveling through Pennsylvania, unfortunately no pets allowed. Room was very clean and looked newly renovated. Very quiet location. Exactly what we were looking for after a long day of travel.
We're so pleased to know that you felt safe and comfortable with us. Chambersburg is a lovely, friendly community and we appreciate having such great guests choosing to stay with us. Thank you.
I have stayed here several times on business to Chambersburg, PA. This Hampton Inn is quiet with clean rooms. All as expected with a Hampton stay. Close to the interstate exit but away from the main shopping area of town so not a lot of traffic near by, but everything you could need is on exit up.
We appreciate that you continue to choose to stay with us when you're in Chambersburg. Thank you for your review!
This was a great choice in hotels, much better than the Quality Inn chain. Always loved Hampton and by in large they are one of the better brands. Nice breakfast choice (no powdered eggs). Easy access to internet no confusing passwords they just make business travel easy! Love the new decor which makes the hotel feel more upscale. You don't...
We want to thank you for giving us such a nice review!
What room did you happen to stay in?
I normally stay at other Hilton brands like the Hilton Garden but this is the only Hilton property near by my client. I have to say that I am so far pleased with the staff here. The room is clean and comfortable.
The only two issues I have so far and not sure if it is a Hampton Inn thing or not, but not sure why they don't have King or Queen size beds here? The double is pretty small for a guy built like myself.
Also, the room that I am in and the hall smells as if it use to be a smoking allowed hotel in the past. It has that distinct old smokers smell to it.
Thanks for your post Slim P.
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Vacation and Spa Expo 2014 Starts in Sofia
A total of 250 companies and organizations will present their tourism and vacation offers at the "Vacation and Spa Expo 2014" in Sofia, Bulgaria.
The event starts on Thursday at the Inter Expo Center in Sofia and will last until Saturday.
The Altai region in Russia, a leading Turkish company for medical tourism, and software companies offering tourist services from Germany and Greece will be among the participants in the exhibition. There will also be stands of tourist agencies from the neighboring countries.
Traditionally, the companies will be offering tourist packages at discount prices, if booked and paid during the expo.
- » Bulgarians Complete More Holiday Trips, Excursions Abroad in June
- » Balkan Holidays To Launch Glasgow-Varna Flights Next Summer
- » Bulgarian Couple Hitch-hikes to India in 511 Days
- » Low-Cost Carrier easyJet Launches Sofia-London Stansted Flights in Winter
- » Bulgaria Ranks Among Top 3 Most Popular Destinations for TUI Russia This Summer
- » Early Launch of Struma Highway's Lot 4


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Interest Master
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You need not rely on someone else every time you have to complete your everyday activities. Take change and learn to do things all by yourself. This interest caters to all those seeking handy and quick assistance to make things simpler. Join and read tips on how to do basic things without hassle. Post your stories and read what others are talking about.
|Swing to the tunes of Phantom's latest
|US Church to be renovated as a Gurudwara
|This man teaches us all about honesty!


text:
EU Exempts Long-Haul Flights from ETS Until 2017
The European Parliament yesterday postponed, to 2017, the date by which the EU's Emissions Trading System will apply to the entire length of flights in and out of Europe.
The 458-120 vote brings three decades of contentious negotiation to a close, Reuters reports.
EU rules bringing aviation into the ETS, with airlines required to cover the entire length of flights starting from or ending in Europe, originally took effect in 2012. A number of nations protested, with China and the US threatening retaliation.
In November 2012, the European Commission announced it would "stop the clock" for one year on the rules, following a decision by the International Civil Aviation Organization to consider a global market-based mechanism. And last October, the ICAO agreed to create such a market-based program starting in 2020, although details won't decided in 2016.
With yesterday's vote, only the portions of flights within the EU will be included in the ETS, at least until 2017. The parliament picked that end-date because the European Commission hopes the ICAO will hammer out its deal by then, the BBC reports.
The vote also delays a deadline to cover 2013 emissions, by one year, to April 2015. And the new rules require EU member states to report how they spend revenues from the ETS, in an effort to ensure that this money is used to combat climate change.
EU governments had wanted to extend the long-haul exemption to run until 2020. The parliament's decision also runs counter to a vote by its environment committee. That panel rejected a long-haul flight exemption, running until 2016, which had been brokered by EU diplomats. At the time it seemed the exemption proposal might not have enough votes to pass the full parliament.
The European Low Fares Airline Association, which represents airlines such as Ryanair and Easyjet that fly almost entirely within Europe, criticized the vote. It said that unless the EU reverses its decision, ELFAA will have no choice but to revive a legal challenge.
Emissions trading offers the best and most cost-effective way of mitigating aviation emissions and climate impact by 2050, according to a report by Manchester Metropolitan University's Centre for Air Transport and Environment.
An analysis by Bloomberg New Energy Finance and the Environmental Defense Fund found the aviation industry could achieve its goal of carbon-neutral growth from 2020 by tapping into the available supply of carbon credits, at a cost to the industry as low as $4 per metric ton of CO2.
Picture credit: Kuster & Wildhaber via Flickr
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World wide aiation industry should work on aciheving its goal of carben neutral by invoation – Bio fuel – Solar PV
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This property allows you to book online with a credit card. After submitting a reservation request, the owner or manager has 24 hours to accept, at which time your card will be charged and you will receive an email confirmation
Other areas nearby to Bridgman:
Recent Southwest reviews
"The house was clean and nicely furnished. It had everything we needed. We really enjoyed being able to walk to town. We would definitely recommend this house to others!"Guest: Jill H. Date of Stay: July 2015 Review Submitted: July 20, 2015View listing
"We took entire family from age 3 to 65. There was something for everyone. The cabin was lovely and the grounds were beautiful. We would all love to go back"Guest: Ellen S. Date of Stay: July 2015 Review Submitted: July 22, 2015View listing
"We loved Haven of Bliss. It was so comfortable and relaxing. Everything we could have needed was graciously provided. My favorite place for the week - the tiny sunroom just off the kitchen. Our time at the cottage was just what we needed!"Guest: Carol M. Date of Stay: June 2015 Review Submitted: June 19, 2015View listing
"Lots of room, great pool and patio area, close to beach, dunes, etc. Very comfortable for 14 people. We had a great time relaxing in this beautiful home."Guest: dh Date of Stay: June 2015 Review Submitted: July 14, 2015View listing
Featured Destinations: Estes Park Cabins, Cabins in Colorado, Starved Rock Cabins, Wisconsin Dells Cabins


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Quality Assurance Engineer III
United States - Last active: 12 days ago - Tests: 2
I am an experienced quality assurance engineer, 10+ years in the industry. I work extremely well as an independent detail-oriented player. My work history includes black box and white box testing. Can create test cases based on existing test plans as well as create test plans and cases for new feature additions. Knowledge of levels of black box testing (simple and general functionality, boundary, etc.) and ability to write corresponding test cases. Can run tests both manually and through automation. Use python skills for command line based automation and Javascript (with Selenium) for testing of web applications. Can integrate new tests into existing automation harnesses as well as implement new ones.
Danish Shaukat
Pakistan - Last active: 25 days ago - Tests: 8 - Portfolio: 5
Professional Summary ================= - Extensive experience in Software Quality Assurance and managing multiple QA Team and multiple QA Projects. - Extensive Experience in Data Entry, Email Handling and Responses, Virtual Assistance and Customer Support and Representation. - Experience in Mobile application development Android and iPhone and delivered many successful projects with great quality. o Web Base Quality Assurance o Desktop Applications o iPhone Applications and Games o Android Applications and Games o Windows Mobile Applications and Games o Performance Testing, Load Testing, Stress Testing, System Testing o Test Strategies, Planning, Budgeting, Use Cases etc - An efficient and reliable Associate Project Manager and Project Coordinator with 3 years experience of Managing iOS/Android Games and Applications. Strong track record in project delivery from both an execution and stakeholder management perspective. Managing Quality Teams, Project and Resource budgeting. - Expert in Data Entry, Email Responses and Customer Support - Expert in Translation from English to Urdu, English to Punjabi, English to Arabic EXPERIENCE OUTLOOK Position Company Experience Project Manager / QA Head of Dept (iPhone/Android) Game View Studios Pvt Limited Pakistan May 2013 – onwards Project Coordinator and Principal SQA Engineer (iPhone/Android) Game View Studios Pvt Limited Pakistan, Subsidary DeNA Japan July 2011 – April 2013 Principal SQA Engineer/Team Lead Quality Assurance Game View Studios Pvt Limited Pakistan, Subsidary DeNA Japan July 2010 – June 2011 Senior SQA Engineer/Team Lead Quality Assurance Cambridge Docs, Pvt Limited Pakistan December 2007 – July 2010 Software Quality Assurance Engineer/Team Lead Softech Systems Pvt Ltd November 2005 – November 2007 SKILLS Computer Related Concepts: • Extensive experience in iOS, Android, Window Applications and Game Testing, Feature Designing and Metadata designing and Developement. • Experience in testing Web based Application, desktop applications, iPhone applications, Android applications, Blackberry and Nokia applications and expert in Games testing. • Experience Project Manager and has experience of Project Management methodologies and has lead many teams and successful projects. • Languages: C/C++, VC, Vb.Net, Asp, Php • Preparing Test scenarios / Test cases / Test scripts / Test Sizing / User Manuals, Getting started Documents, Technical Docs • Microsoft Visio, Bugzilla, Oracle, Rational Rose, Front Page, Unfuddle, • Good Command Over Software Engineering especially Software Quality Assurance • Good Communication, Analytical, Administrative Skills • Testing Technologies – Black Box (Functional, Regression, Acceptance, Performance, Boundary Value, Integration, Stress, Load, Connectivity etc.) • Good Data Structures, Algorithms , Compiler concepts. Business Administration Concepts: • Marketing concepts • Human Resource Management and Organizational Behavior Concepts • Operational Management Concepts • Financial and Managerial Accounting Concepts EDUCATION Degree College / University Passing Year Masters in Business Administration – Majors in Finance and HR Institute of Management Sciences (Pak-Aims) 2007 (CGPA: 3.65) BS Computer Sciences (BCS) – Majors in Software Engineering Institute of Management Sciences (Pak-Aims) 2005 (CGPA: 3.08) BA – Journalism, Education Private 2005 PROFESSIONAL PROJECTS DreamFish (iOS, Android Social Game) Project Description DreamFish is a famous aquarium-based iPhone and Android Social game. 'Tap Fish' which was at the top of the charts in iOS and Android with millions of active users. Project Type iOS and Android Social Game Role Project Manager and Head of Quality Department of the Project Responsibility Development of New Features, Client and Resource handling and Management, Team Lead, Test Estimates, Assigning Team Tasks and Roles, Test Plans, Reviewing other test cases, Performance Testing, Regression Testing, Connectivity Testing, Memory Testing and Mobile Level Testing HayRide (iOS, Android, Windows Social Game) Project Description HAYRIDE is a farming game with smooth controls. You will grow crops and fruits, raise livestock animals, produce goods, fill orders from the townsfolk, sell your goods at the roadside shop, and even visit other farms. And you will have many followers if you decorate your farm nicely! Project Type iOS, Windows and Android Social Game Role Project Manager and Head of Quality Department of the Project Responsibility Development of New Features, Client and Resource handling and Management, Team Lead, Test Estimates, Assigning Team Tasks and Roles, Test Plans, Reviewing other test cases, Performance Testing, Regression Testing, Connectivity Testing, Memory Testing and Mobile Level Testing
.: Top Expert IOS Professional Developer:.
United Arab Emirates - Last active: 5 days ago - Tests: 3 - Portfolio: 4
I am an expert developer with 4 year experience of IOS games and apps.I have excellent command over cocos2d and cocoa touch along with open source libraries.My speciality lies in quality work and I believe in total customer satisfaction by doing job before time. My core competency lies in developing top notch apps, which gain maximum market shares.It is my passion to develop user friendly UI with eye catching graphics to get final product with maximum business shares in market. Besides that I am IT consultant and entrepreneur. I am seeking oppourtunities to get good business for you and your company. Thanks for your time
- Objective-C
- Mobile App Development
- Cocoa Touch
- Cocos2d
- xml web services
- Game Development
- MySQL Administration
- Game Testing
- iOS Jailbreaking
- Apple Xcode
- Apple UIKit Framework
- iOS Development
- Education Technology
- Home Automation
- GUI Design
- User interface design
- Graphic design
- Project management
- TeamViewer
- Assembly Language
- iPhone App Development
- Internet Marketing
- Social Media Marketing
- Computer Networking
- Embedded Systems
- Systems Development
- Business Development
- Website Development
Groups: BoonEx
Associated with: skoolofapps
C++/C#/Java/Obj-C/PHP, BES, UC, Exchange/Domino, Cisco
South Africa - Last active: 02/21/2013 - Tests: 11
Over the last 9 years, I have developed software for various platforms, including desktop, web and mobile using C++, C#, Java and Objective C. I have also managed complete computer network deployments for various companies, based on Windows, Linux, Mac OS X and Solaris platforms. I am also experienced with network infrastructure, routing & switching, unified communications and messaging. Proficient in Cisco router & switch administration, CUCM, CCME, Unity and security appliances. My skills also extend to Microsoft UC (Lync Server/OCS), Exchange, BlackBerry Enterprise Server and IBM Lotus Domino.
- Blackberry app development
- Android App Development
- iPhone App Development
- Pocket PC
- Java
- MySQL Administration
- .NET Framework
Maasss Technologies
India - Last active: 3 months ago - Tests: 1 - Portfolio: 18
Maasss Technologies is a software development firm focused on providing an integrated service offering that includes data center services, software development, mobile application development and e-commerce solutions. We believe in client engagement, our first intention is to first understand your business, then perform a detailed due diligence. We suggest innovative and creative designs that can effectively communicate with your potential clients or daily visitors. We continuously update our web development and deployment technology. Our seamless solutions are administered using: 1. LAMP Stack (Linux, Apache, MySQL, PHP) 2. Microsoft technologies (Dot Net, SQL Server, SharePoint) 3. Joomla and Wordpress 4. HTML5 5. CSS Our Enterprise CMS Website Development services are diverse, easy to use, and loaded with features. We provide Content Management System Services with SEO compatible URLs. Our team of hard core professionals provides seamless integration of website with open source CMS application. PHP based CMS is available with easy to use interface that is conveniently used by technical as well as non-technical users. You not only smoothly manage your web content but also achieve digital marketing success. Client engagement is our forte; our team guides you through all features and functionalities of CMS. This approach of ours helps you seamlessly start using CMS. We believe that being a customer driven entity we have the capacity and capability to carry on any type of a project with an expertise and efficiency that cannot be matched by a freelancer. With us you get: 1.) 2+ years of experience 2.) Post-delivery support 3.) Prompt communication 4.) Cutting edge web technology practices 5.) Full value of your investment 6.) Shorter turnaround time Web & Mobile Application Technologies PHP, ASP.NET, Android, Blackberry, Windows Mobile, iOS Database Platform MySQL, MSSQL Server, Oracle, MS Access Operating Systems Linux, Windows, Sun Solaris, Novell NetWare, Macintosh Design Studios Dreamweaver, Flash, Photoshop, CorelDraw, Illustrator, Fireworks, Aftereffects, 3D Studio etc.
iOS Developer
Tunisia - Last active: 1 month ago - Tests: 1
I have been developing for the iOS platform for more than 2 years that i have obtained a great experiance in mobile apps development
Expert iPhone/iPad/Android developer with objective c,c,Xcode,sqlite,c
India - Last active: 4 days ago - Tests: 3 - Portfolio: 3
Experienced iPhone, Android and iPad Developer with over 4 years general(desktop/mobile/emedded) programming. Programming languages:Java,Android,objectice c, cocoa, C/C++, PHP, HTML, asm. Fluent use of any new frameworks. Can work as standalone programmer with minimum directions from Your side, also as a good team worker with co-operations and agile management. Sphere of experience: Android/Windows/DSP/Web development; User Interface design;User Experience; Data protocol creation and management; Feedback control system development; SCADA design; Engineering and design of control systems robots and machines; Analysis. Strong mathematical and system control knowledge. Additional UI/UX design skills. Available at: skype/gtalk/Yahoo/Facebook
- Objective-C
- Apple Xcode
- Google Maps API
- Mac OS App Development
- iPhone App Development
- Android App Development
- SQLite Administration
- Core Java
- Cocoa
- Cocoa Touch
- Cocos2d
Associated with: KBIHM Consulting Pvt.Ltd.
Solution Summit (Website designing and Development, 3-D, Graphics)
Pakistan - Last active: 1 day ago - Tests: 2 - Portfolio: 1
My objective is to make a chain of satisfied potential clients with a mixture of quality and low cost solutions.
Mobile App Developer (iPhone, Android, BlackBerry, Windows)
India - Last active: 6 days ago - Tests: 2 - Portfolio: 4
Over the last few years, I have developed a wide range of mobile apps for iPhone, Android, Blackberry, Windows, Samsung Bada, WAP, Mobile Supported Website and Development, Web Services using latest tools and technology including apps for startup companies and small businesses. My core competency lies in complete end-end management of a new mobile application, mobile web application, website development project, and I am seeking opportunities to build mobile applications, mobile web applications from the ground up for you or your business. I also have some experience in the following areas: MySQL, MSSQL, Web Services, jQTouch, jQuery, HTML 5, Ajax, OOP, and software design and testing.
- iPhone App Development
- Android App Development
- Blackberry app development
- Windows Phone
- JavaScript
- Software QA Testing
Apple SmartWatch Expert | iOS Expert | Sr. iOS Developer | iOS Archite
India - Last active: 1 month ago - Tests: 2 - Portfolio: 5
"TOGAF9 Certified | Mobility Architect | iOS Architect | Mobile Banking Security Expert | " Mobile Solutions Architect, with over 7+ years of experience in the design and development of mobile solutions, seeks an opportunity to further get to the core of mobile solutions architecture, and breed a foundation for technological advancement. Profile Summary: 1. Delivered 180+ world class iOS Apps. 2. Executed fundamental functions pertaining to complete systems lifecycle management, ensuring high quality deliverables 3. Determined project requirements, established quality standards, and implemented IT solutions Developed mobile application architectures for successful business expansion 4. High degree of involvement in project management; developed and applied IT solutions and techniques to increase productivity and mitigate potential risks 5. Controlled and guided mobile technologies, extended business solutions, in order to facilitate optimal implementation of business process strategies 6. Experienced in determining mobile application roadmaps and systems integration 7. Designed and developed integration patterns, aimed at spanning systems hardware, networking environments, business processes and platforms Key Skills: 1. Experienced in leading cross-functional projects 2. In depth knowledge of web services and portals 3. Closely familiar with enterprise service interoperability 4. Proficient in data security and the improvement of information accessibility, aiding the process of decision making and the prevention of data loss 5. Functional and developmental knowledge of HTML5, Android OS, Windows Mobile, and Blackberry OS 6. Sound knowledge in the implementation of agile methodology
- Objective-C
- iPhone App Development
- SQLite Administration
- Architecture
- iOS Development
- iOS Jailbreaking
- Mobile Development Framework
- Internet Security
Associated with: uInnoTech Solutions Pvt. Ltd Agency


text:
"The only chili recipe I use! I add a can of corn. My secret to making this man-approved is to add one bottle/can of beer for extra liquid. Great on game days!" – Sewdomestic14
Recipe of the Day
Slow Cooker Italian Beef
Roast beef simmered with Italian-style spices, pepperoncini and beef broth for a tasty sandwich.
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Tying the roast, and cooking at high heat, ensure even roasting.


text:
Are you Carlo M Croce?Claim your profile
Publications (706)6453.61 Total impact
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ABSTRACT: B-cell chronic lymphocytic leukemia (CLL) is the most common human leukemia occurring as indolent or aggressive form. CLL clinical features and genetic abnormalities are well documented, but molecular details are still under investigation. MicroRNAs are small non-coding RNAs involved in several cellular processes and expressed in a tissue-specific manner. MicroRNAs regulate gene expression, and their deregulation can alter expression levels of genes involved in development/progression of tumors. In CLL, microRNAs can function as oncogenes or tumor suppressors and can also serve as markers for CLL onset/progression. Here, we discuss the most recent findings about the role of microRNAs in CLL and how this knowledge can be used to identify new biomarkers and treatment approaches.Journal of Hematology & Oncology 12/2015; 8(1). DOI:10.1186/s13045-015-0112-x · 4.93 Impact Factor
- Proceedings of the National Academy of Sciences 07/2015; DOI:10.1073/pnas.1502068112 · 9.81 Impact Factor
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ABSTRACT: MicroRNAs (miRNAs) are short noncoding RNAs with a length of approximately 22 nucleotides that are involved in posttranscriptional regulation of gene expression. miRNAs cover an important role in all biological processes, and aberrant miRNA expression is commonly associated with cancer. Recent discoveries have associated the involvement of miRNA in an increasingly large number of biological processes, including cachexia. The cachexia syndrome is a debilitating state of cancer that is, at least in part, associated with apoptosis. The mechanism through which tumors promote the characteristic distal loss of muscle and fat mass during the cachectic process is still not deeply investigated. In this review, we briefly describe the role of miRNAs in cancer development and cachexia. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: firstname.lastname@example.com Journal of Infectious Diseases 07/2015; 212(suppl 1). DOI:10.1093/infdis/jiv197 · 5.78 Impact Factor
Article: The role of p19 and p21 H-Ras proteins and mutants in miRNA expression in cancer and a Costello syndrome cell model[Show abstract] [Hide abstract]
ABSTRACT: P19 H-Ras, a second product derived from the H-Ras gene by alternative splicing, induces a G1/S phase delay, thereby maintaining cells in a reversible quiescence state. When P21 H-Ras is mutated in tumour cells, the alternative protein P19 H-Ras is also mutated. The H-Ras mutation Q61L is frequently detected in different tumours, which acts as constitutive activator of Ras functions and is considered to be a strong activating mutant. Additionally, a rare congenital disorder named Costello Syndrome, is described as a H-Ras disorder in children, mainly due to mutation G12S in p19 and p21 H-Ras proteins, which is present in 90 % of the Costello Syndrome patients. Our aim is to better understand the role of p19 and p21 H-Ras proteins in the cancer and Costello Syndrome development, concerning the miRNAs expression. Total miRNAs expression regulated by H-Ras proteins were first analyzed in human miRNA microarrays assays. Previously selected miRNAs, were further analyzed in developed cell lines containing H-Ras protein mutants, that included the G12S Costello Syndrome mutant, with PCR Real-Time Taq Man miRNA Assays primers. This study describes how p19 affects the RNA world and shows that: i) miR-342, miR-206, miR-330, miR-138 and miR-99b are upregulated by p19 but not by p19W164A mutant; ii) anti-miR-206 can restore the G2 phase in the presence of p19; iii) p19 and p21Q61L regulate their own alternative splicing; iv) miR-206 and miR-138 are differentially regulated by p19 and p21 H-Ras and v) P19G12S Costello mutants show a clear upregulation of miR-374, miR-126, miR-342, miR-330, miR-335 and let-7. These results allow us to conclude that the H-Ras G12S mutation plays an important role in miRNA expression and open up a new line of study to understand the consequences of this mutation on Costello syndrome. Furthermore, they suggest that oncogenes may have a sufficiently important impact on miRNA expression to promote the development of numerous cancers.BMC Medical Genetics 07/2015; 16(1):46. DOI:10.1186/s12881-015-0184-z · 2.45 Impact Factor
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ABSTRACT: TRAIL (TNF-related apoptosis-inducing ligand) is a promising anticancer agent that can be potentially used as an alternative or complementary therapy because of its specific antitumor activity. However, TRAIL can also stimulate the proliferation of cancer cells through the activation of NF-κB, but the exact mechanism is still poorly understood. In this study, we show that chronic exposure to subtoxic concentrations of TRAIL results in acquired resistance. This resistance is associated with the increase in miR-21, miR-30c, and miR-100 expression, which target tumor-suppressor genes fundamental in the response to TRAIL. Importantly, down-regulation of caspase-8 by miR-21 blocks receptor interacting protein-1 cleavage and induces the activation of NF-κB, which regulates these miRNAs. Thus, TRAIL activates a positive feedback loop that sustains the acquired resistance and causes an aggressive phenotype. Finally, we prove that combinatory treatment of NF-κB inhibitors and TRAIL is able to revert resistance and reduce tumor growth, with important consequences for the clinical practice.Proceedings of the National Academy of Sciences 06/2015; 112(26). DOI:10.1073/pnas.1504630112 · 9.81 Impact Factor
Article: miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model.[Show abstract] [Hide abstract]
ABSTRACT: The involvement of microRNAs (miRNAs) in chronic lymphocytic leukemia (CLL) pathogenesis suggests the possibility of anti-CLL therapeutic approaches based on miRNAs. Here, we used the Eµ-TCL1 transgenic mouse model, which reproduces leukemia with a similar course and distinct immunophenotype as human B-CLL, to test miR-181b as a therapeutic agent.In vitro enforced expression of miR-181b mimics induced significant apoptotic effects in human B-cell lines (RAJI, EHEB), as well as in mouse Eµ-TCL1 leukemic splenocytes. Molecular analyses revealed that miR-181b not only affected the expression of TCL1, Bcl2 and Mcl1 anti-apoptotic proteins, but also reduced the levels of Akt and phospho-Erk1/2. Notably, a siRNA anti-TCL1 could similarly down-modulate TCL1, but exhibited a reduced or absent activity in other relevant proteins, as well as a reduced effect on cell apoptosis and viability. In vivo studies demonstrated the capability of miR-181b to reduce leukemic cell expansion and to increase survival of treated mice.These data indicate that miR-181b exerts a broad range of actions, affecting proliferative, survival and apoptotic pathways, both in mice and human cells, and can potentially be used to reduce expansion of B-CLL leukemic cells.Oncotarget 06/2015; · 6.63 Impact Factor
Article: Mechanisms of PD-L1/PD-1 mediated CD8 T-cell dysfunction in the context of aging-related immune defects in the E -TCL1 CLL mouse model[Show abstract] [Hide abstract]
ABSTRACT: T-cell defects, immune suppression and poor anti-tumor immune responses are hallmarks of Chronic Lymphocytic Leukemia (CLL), and PD-1/PD-L1 inhibitory signaling has emerged as a major immunosuppressive mechanism. However, the effect of different microenvironments and the confounding influence of aging are poorly understood. The current study uses the Eμ-TCL1 mouse model, which replicates human T-cell defects, as a preclinical platform to longitudinally examine patterns of T-cell dysfunction alongside developing CLL and in different microenvironments, with a focus on PD-1/PD-L1 interactions. The development of CLL was significantly associated with changes in T-cell phenotype across all organs and function. Although partly mirrored in aging wild-type mice, CLL-specific T-cell changes were identified. Murine CLL cells highly expressed PD-L1 and PD-L2 in all organs, with high PD-L1 expression in spleen. CD3(+)CD8(+) T-cells from leukemic and aging healthy mice highly expressed PD-1, identifying aging as a confounder, but adoptive transfer experiments demonstrated CLL-specific PD-1 induction. Direct comparisons of PD-1 expression and function between aging CLL mice and controls identified PD-1(+) T cells in CLL as a heterogeneous population with variable effector function. This is highly relevant for therapeutic targeting of CD8(+) T-cells, showing the potential of reprogramming and selective subset expansion to restore anti-tumor immunity. Copyright © 2015 American Society of Hematology.Blood 05/2015; DOI:10.1182/blood-2015-02-626754 · 10.43 Impact Factor
Dataset: 3909-54134-1-SP (1)
Article: MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression[Show abstract] [Hide abstract]
ABSTRACT: The transcription factor MYC is a proto-oncogene regulating cell proliferation, cell cycle, apoptosis and metabolism. The recent identification of MYC-regulated long noncoding RNAs (lncRNAs) expands our knowledge of the role of lncRNAs in MYC functions. Here, we identify MYC-repressed lncRNAs named MYCLo-4, -5 and -6 by comparing 3 categories of lncRNAs (downregulated in highly MYC-expressing colorectal cancer, up-regulated by MYC knockdown in HCT116, upregulated by MYC knockdown in RKO). The MYC-repressed MYCLos are implicated in MYC-modulated cell proliferation through cell cycle regulation. By screening cell cycle-related genes regulated by MYC and the MYC-repressed MYCLos, we identified the MYC-repressed gene GADD45A as a target gene of the MYC-repressed MYCLos such as MYCLo-4 and MYCLo-6.Oncotarget 05/2015; · 6.63 Impact Factor
Article: Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature[Show abstract] [Hide abstract]
ABSTRACT: Differentiation of lung vascular smooth muscle cells (vSMCs) is tightly regulated during development or in response to challenges in a vessel specific manner. Aberrant vSMCs specifically associated with distal pulmonary arteries have been implicated in the pathogenesis of respiratory diseases, such as pulmonary arterial hypertension (PAH), a progressive and fatal disease, with no effective treatment. Therefore, it is highly relevant to understand the underlying mechanisms of lung vSMC differentiation. miRNAs are known to play critical roles in vSMC maturation and function of systemic vessels; however, little is known regarding the role of miRNAs in lung vSMCs. Here, we report that miR-29 family members are the most abundant miRNAs in adult mouse lungs. Moreover, high levels of miR-29 expression are selectively associated with vSMCs of distal vessels in both mouse and human lungs. Furthermore, we have shown that disruption of miR-29 in vivo leads to immature/synthetic vSMC phenotype specifically associated with distal lung vasculature, at least partially due to the derepression of KLF4, components of the PDGF pathway and ECM-related genes associated with synthetic phenotype. Moreover, we found that expression of FBXO32 in vSMCs is significantly upregulated in the distal vasculature of miR-29 null lungs. This indicates a potential important role of miR-29 in smooth muscle cell function by regulating FBXO32 and SMC protein degradation. These results are strongly supported by findings of a cell autonomous role of endogenous miR-29 in promoting SMC differentiation in vitro. Together, our findings suggested a vessel specific role of miR-29 in vSMC differentiation and function by targeting several key negative regulators.PLoS Genetics 05/2015; 11(5):e1005238. DOI:10.1371/journal.pgen.1005238 · 8.17 Impact Factor
Article: Retraction notice to "Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice" [Eur J Cancer 47 (2011) 470–478]European Journal of Cancer 04/2015; 51(6). DOI:10.1016/j.ejca.2015.03.001 · 4.82 Impact Factor
Article: Genetic Manipulation of Homologous Recombination In Vivo Attenuates Intestinal Tumorigenesis[Show abstract] [Hide abstract]
ABSTRACT: Although disruption of DNA repair capacity is unquestionably associated with cancer susceptibility in humans and model organisms, it remains unclear if the inherent tumor phenotypes of DNA repair deficiency syndromes can be regulated by manipulating DNA repair pathways. Loss-of-function mutations in BLM, a member of the RecQ helicase family, cause Bloom's syndrome (BS), a rare, recessive genetic disorder that predisposes to many types of cancer. BLM functions in many aspects of DNA homeostasis, including the suppression of homologous recombination (HR) in somatic cells. We investigated whether BLM overexpression, in contrast to loss-of-function mutations, attenuated the intestinal tumor phenotypes of ApcMin/+ and ApcMin/+;Msh2-/- mice, animal models of familial adenomatous polyposis coli (FAP). We constructed a transgenic mouse line expressing human BLM (BLM-Tg) and crossed it onto both backgrounds. BLM-Tg decreased adenoma incidence in a dose-dependent manner in our ApcMin/+ model of FAP, although levels of GIN were unaffected, and concomitantly increased animal survival over 50%. It did not reduce intestinal tumorigenesis in ApcMin/+;Msh2-/- mice. We used the pink-eyed unstable (pun) mouse model to demonstrate that increasing BLM dosage in vivo lowered endogenous levels of HR by two-fold. Our data suggests that attenuation of the Min phenotype is achieved through a direct effect of BLM-Tg on the HR repair pathway. These findings demonstrate that HR can be manipulated in vivo to modulate tumor formation at the organismal level. Our data suggests that lowering HR frequencies may have positive therapeutic outcomes in the context of specific hereditary cancer predisposition syndromes, exemplified by FAP. Copyright © 2015, American Association for Cancer Research.Cancer Prevention Research 04/2015; 8(7). DOI:10.1158/1940-6207.CAPR-15-0001-T · 5.27 Impact Factor
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ABSTRACT: Invariant natural killer T cells (iNKT cells) are CD1d-restricted, lipid antigen-reactive T lymphocytes with immunoregulatory functions. iNKT cell development in the thymus proceeds through subsequent stages, defined by the expression of CD44 and NK1.1, and is dictated by a unique gene expression program, including microRNAs. Here, we investigated whether miR-155, a microRNA involved in differentiation of most hematopoietic cells, played any role in iNKT cell development. To this end, we assessed the expression of miR-155 along iNKT cell maturation in the thymus, and studied the effects of miR-155 on iNKT cell development using Lck-miR-155 transgenic mice, which over express miR-155 in T cell lineage under the lymphocyte-specific protein tyrosine kinase (Lck) promoter. We show that miR-155 is expressed by newly selected immature wild-type iNKT cells and turned off along iNKT cells differentiation. In transgenic mice, miR-155 over-expression resulted in a substantial block of iNKT cell maturation at Stage 2, in the thymus toward an overall reduction of peripheral iNKT cells, unlike mainstream T cells. Furthermore, the effects of miR-155 over-expression on iNKT cell differentiation were cell autonomous. Finally, we identified Ets1 and ITK transcripts as relevant targets of miR-155 in iNKT cell differentiation. Altogether, these results demonstrate that a tight control of miR-155 expression is required for the development of iNKT cells.Frontiers in Immunology 03/2015; 6:140. DOI:10.3389/fimmu.2015.00140
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ABSTRACT: Systemic siRNA administration to target and treat glioblastoma, one of the most deadly cancers, requires robust and efficient delivery platform without immunogenicity. Here we report newly emerged multivalent naked RNA nanoparticle (RNP) based on pRNA 3-way-junction (3WJ) from bacteriophage phi29 to target glioblastoma cells with folate (FA) ligand and deliver siRNA for gene silencing. Systemically injected FA-pRNA-3WJ RNPs successfully targeted and delivered siRNA into brain tumor cells in mice, and efficiently reduced luciferase reporter gene expression (4-fold lower than control). The FA-pRNA-3WJ RNP also can target human patient-derived glioblastoma stem cells, thought to be responsible for tumor initiation and deadly recurrence, without accumulation in adjacent normal brain cells, nor other major internal organs. This study provides possible application of pRNA-3WJ RNP for specific delivery of therapeutics such as siRNA, microRNA and/or chemotherapeutic drugs into glioblastoma cells without inflicting collateral damage to healthy tissues.Oncotarget 03/2015; · 6.63 Impact Factor
- Advances in Biological Regulation 03/2015; 58. DOI:10.1016/j.jbior.2015.02.001
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ABSTRACT: The first transgenic mouse of the TCL1 oncogene was described more than 15 years ago, and since then, the overexpression of the gene in T- and B-cells in vivo has been extensively studied to reveal the molecular details in the pathogenesis of some lymphocytic leukemias. This review discusses the main features of the original TCL1 models and the different lines of research successively developed with particular attention to genetically compound mice and the therapeutic applications in drug development.Gene Expression 02/2015; 16(3). DOI:10.3727/105221615X14181438356256 · 1.67 Impact Factor
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ABSTRACT: This volume provides an overview of RNA bioinformatics methodologies, including basic strategies to predict secondary and tertiary structures, and novel algorithms based on massive RNA sequencing. Interest in RNA bioinformatics has rapidly increased thanks to the recent high-throughput sequencing technologies allowing scientists to investigate complete transcriptomes at single nucleotide resolution. Adopting advanced computational technics, scientists are now able to conduct more in-depth studies and present them to you in this book. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and equipment, step-by-step, readily reproducible bioinformatics protocols, and key tips to avoid known pitfalls. Authoritative and practical, RNA Bioinformatics seeks to aid scientists in the further study of bioinformatics and computational biology of RNA.RNA Bioinformatics, Methods in Molecular Biology edited by Ernesto Picardi, 02/2015: chapter 25: pages 388; Humana Press, Springer., ISBN: ISBN 978-1-4939-2290-1
Article: Decreased miR-199 augments visceral pain in patients with IBS through translational upregulation of TRPV1[Show abstract] [Hide abstract]
ABSTRACT: Many patients with irritable bowel syndrome IBS not only have abdominal pain but also may suffer from visceral hypersensitivity and heighted visceral nociception. Moreover, IBS has few effective therapeutic agents and mechanisms of disease are unclear. Our goals were to (i) identify microRNA (miRNA) expression, signalling and targets in human colon (controls; patients with IBS); (ii) verify in vitro, IBS-associated changes in miRNAs, especially miR-199, which is complementary to the transient receptor potential vanilloid type 1 (TRPV1) gene; and (iii) determine whether modulating the expression of miRNAs in vivo, especially miR-199, reverses associated changes and pathological hallmarks of visceral hypersensitivity via TRPV1 signalling. We evaluated 45 patients with diarrhoea-predominant IBS (IBS-D) and 40 controls with (1) visceral pain severity score and (2) colonoscopy with biopsies. miRNA expression was evaluated in human colon following miRNA array analysis. Luciferase assays were done to confirm relationships between miR-199 and TRPV1 expression. A rat model of visceral hypersensitivity was used to study miR-199 and its target gene (TRPV1) expression in dorsal root ganglion (DRG) and colon in vivo. Gut miR-199a/b expression in IBS-D was significantly decreased, which correlated directly with both increased visceral pain scores and TRPV1 expression. In vivo upregulation of miR-199a by intraperitoneal injection of lenti-miR-199a precursors decreased visceral hypersensitivity via diminished TRPV1 signalling. Decreased colonic miR-199a/b correlates with visceral pain in patients with IBS-D. Similarly, reduced miR-199a expression in rat DRG and colon tissue is associated with heightened visceral hypersensitivity. In vivo upregulation of miR-199a decreases visceral pain via inhibition of TRPV1 signalling. Thus, miR-199 precursors may be promising therapeutic candidates for the treatment in patients with visceral pain. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Gut 02/2015; DOI:10.1136/gutjnl-2013-306464 · 13.32 Impact Factor
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ABSTRACT: Background: The functions of long noncoding RNAs (lncRNAs) have been identified in several cancers, but the roles of lncRNAs in colorectal cancer (CRC) are less well understood. The transcription factor MYC is known to regulate lncRNAs and has been implicated in cancer cell proliferation and tumorigenesis. Methods: CRC cells and tissues were profiled to identify lncRNAs differentially expressed in CRC, from which we further selected MYC-regulated lncRNAs. We used luciferase promoter assay, ChIP, RNA pull-down assay, deletion mapping assay, LC-MS/MS and RNA immunoprecipitation to determine the mechanisms of MYC regulation of lncRNAs. Moreover, soft agar assay and in vivo xenograft experiments (four athymic nude mice per group) provided evidence of MYC-regulated lncRNAs in cancer cell transformation and tumorigenesis. The Kaplan-Meier method was used for survival analyses. All statistical tests were two-sided. Results: We identified lncRNAs differentially expressed in CRC (P < .05, greater than two-fold) and verified four lncRNAs upregulated and two downregulated in CRC cells and tissues. We further identified MYC-regulated lncRNAs, named MYCLos. The MYC-regulated MYCLos may function in cell proliferation and cell cycle by regulating MYC target genes such as CDKN1A (p21) and CDKN2B (p15), suggesting new regulatory mechanisms of MYC-repressed target genes through lncRNAs. RNA binding proteins including HuR and hnRNPK are involved in the function of MYCLos by interacting with MYCLo-1 and MYCLo-2, respectively. Knockdown experiments also showed that MYCLo-2, differentially expressed not only in CRC but also in prostate cancer, has a role in cancer transformation and tumorigenesis. Conclusions: Our results provide novel regulatory mechanisms in MYC function through lncRNAs and new potential lncRNA targets of CRC.JNCI Journal of the National Cancer Institute 02/2015; 107(4):dju505. DOI:10.1093/jnci/dju505 · 15.16 Impact Factor
Article: TCL1 targeting miR-3676 is codeleted with tumor protein p53 in chronic lymphocytic leukemia[Show abstract] [Hide abstract]
ABSTRACT: B-cell chronic lymphocytic leukemia (CLL) is the most common human leukemia and dysregulation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene is a contributing event in the pathogenesis of the aggressive form of this disease based on transgenic mouse studies. To determine a role of microRNAs on the pathogenesis of the aggressive form of CLL we studied regulation of TCL1 expression in CLL by microRNAs. We identified miR-3676 as a regulator of TCL1 expression. We demonstrated that miR-3676 targets three consecutive 28-bp repeats within 3'UTR of TCL1 and showed that miR-3676 is a powerful inhibitor of TCL1. We further showed that miR-3676 expression is significantly down-regulated in four groups of CLL carrying the 11q deletions, 13q deletions, 17p deletions, or a normal karyotype compared with normal CD19(+) cord blood and peripheral blood B cells. In addition, the sequencing of 539 CLL samples revealed five germ-line mutations in six samples (1%) in miR-3676. Two of these mutations were loss-of-function mutations. Because miR-3676 is located at 17p13, only 500-kb centromeric of tumor protein p53 (Tp53), and is codeleted with Tp53, we propose that loss of miR-3676 causes high levels of TCL1 expression contributing to CLL progression.Proceedings of the National Academy of Sciences 02/2015; 112(7):201500010. DOI:10.1073/pnas.1500010112 · 9.81 Impact Factor
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Clendenen Family Vineyards Nebbiolo 'The Pip' 2008
Clendenen Family Vineyards - California - United States - Santa Barbara - Santa Maria Valley
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Additional Information on Clendenen Family Vineyards Nebbiolo 'The Pip' 2008
Clendenen Family Vineyards
Vintage: 2008
2008 saw very high yields across wineries in much of the southern hemisphere, as a result of highly favorable climatic conditions. Although in many areas, these high yields brought with them something of a drop in overall quality, this could not be said for South Australia's wines, which were reportedly excellent. Indeed, the 2008 Shiraz harvest in South Australia is said to be one of the most successful in recent decades, and western Australia's Chardonnays are set to be ones to watch out for. New Zealand's Pinot Noir harvest was also very good, with wineries in Martinborough reportedly very excited about this particular grape and the characteristics it revealed this year. Pinot Noir also grew very well in the United States, and was probably the most successful grape varietal to come out of California in 2008, with Sonoma Coast and Anderson Valley delivering fantastic results from this grape. Elsewhere in United States, Washington State and Oregon had highly successful harvests in 2008 despite some early worries about frost. However, it was France who had the best of the weather and growing conditions in 2008, and this year was one of the great vintages for Champagne, the Médoc in Bordeaux, Languedoc-Roussillon and Provence, with Pinot Noir, Cabernet Sauvignon and Chardonnay grapes leading the way. Italy, too, shared many of these ideal conditions, with the wineries in Tuscany claiming that their Chianti Classicos of 2008 will be ones to collect, and Piedmont's Barberesco and Barolo wines will be recognized as amongst the finest of the past decade.
Varietal: Nebbiolo
The dusty purple grapes of the Nebbiolo variety are widely considered to be amongst the finest in the world, and hold many unique characteristics which have secured their place in wine making history. Indeed, almost all of the most respected and sought after red wines of Italy are made using this grape varietal, and it wasn't long before several New World wineries started experimenting with the fruit of this special vine, too. Nebbiolo grapes are renowned for their ability to age beautifully, with their strong and dense tannins mellowing out and becoming more balanced inside the oak. Alongside this, they hold some of the most complex and exciting flavors to be found in any grape, which range from gorgeous notes of black truffle, to aromatic violets and tobacco tones.
Region: California
California has long been the New World's most important and prodigious wine producing regions, with a history which stretches back to the 18th century and the Spanish pioneers who settled here. Today, California produces vast quantities of wine, and if it were a country, it would be the fourth largest producer of wine on earth. Despite experiencing many problems in the mid 20th century, including a very serious blight which almost crippled the state's wine industry, the ideal terroir and excellent climate ensured that Californian wines soon became the envy of the New World once again. California produces a vast range of wines, and utilizes a long list of fine grape varietals, with many wineries and their produce more closely resembling those of France and other Old World countries in regards to character, practices and flavors
Country: United States
The first European settlers to consider growing grapevines in the United States must have been delighted when they discovered the now famous wine regions within California, Oregon and elsewhere. Not even in the Old World are there such fertile valleys, made ideal for vine cultivation by the blazing sunshine, long, hot summers and oceanic breezes. As such, it comes as little surprise that today more than eighty-nine percent of United States wines are grown in the valleys and on the mountainsides of California, where arguably some of the finest produce in the world is found. However, American wine does not begin and end with California, and due to the vast size of the country and the incredible range of terrains and climates found within the United States, there is probably no other country on earth which produces such a massive diversity of wines. From ice wines in the northern states, to sparkling wines, aromatized wines, fortified wines, reds, whites, rosés and more, the United States has endless surprises in store for lovers of New World wines.
Appellation: Santa Barbara
When it comes to Californian wines, the region of Santa Barbara is highly respected, and has an ever growing fan-base who adore the big, characterful and flavorful wines the region produces. Santa Barbara benefits from the same west coast sunshine the rest of the state does, and has a fine set of soils which help give the wines some of their distinctive flavours. The majority of Santa Barbara wines are red, with Cabernet Sauvignon being an important grape varietal for the dozens of wineries which call the county their home. However, white wine production is very much on the increase in Santa Barbara, as wine-makers discover how good the blend of sunshine and Pacific wind can be for many classic French white wine grape varietals.
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A childcare centre supervisor has been stood down after a distraught two-year-old girl was left behind alone at the centre for almost two hours while staff and children went on a picnic.
The toddler was left behind at the Ta Fesilafai Aoga Amata childcare centre in Beach Haven, on Auckland's North Shore, on Friday morning.
It was only after the toddler's mother arrived at the picnic spot in West Auckland that it was discovered the child was missing.
Police, the Education Ministry and the childcare centre are all investigating the incident.
The childcare centre licensee, Sonny Vagana, said a relative of the mother and a relative of one of the childcare workers smashed open a window at the centre and found the distraught girl.
Mr Vagana held a meeting last night with staff to try to find out what happened.
He had spoken yesterday to the girl's mother, who had complained to police, and was keeping her informed about the centre's investigation.
"Everyone's pretty distraught about it, especially the staff."
Mr Vagana said the supervisor in charge had taken it the worst but he was not making excuses for what happened.
"It's unacceptable, it should never have happened."
The centre already had robust procedures in place to deal with outings by the children but would implement any changes suggested to prevent similar incidents happening.
"We've let the parents down and we're all disappointed."
Bruce Adin, Education Ministry northern regional manager of early childhood and regional education, said the ministry was notified yesterday morning that a child was left unsupervised at the centre.
Two ministry staff had visited the centre in response to a complaint from the toddler's parent.
Officials were still gathering information and were yet to get a full picture of what happened.
Mr Adin said the centre was generally well managed and offered a sound education programme to children who attended the childcare service.
- North Shore Times
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Game changes again on controversial SkyPath
Gardener hopes to see more Kauri
Beach side campground clinches overwhelming public support
'Charismatic' navy commander remembered
Communication breakdown feared over beach reserve meeting
Single, unemployed and disadvantaged
New group hopes to improve bike shed
Police offer $50,000 reward in West Auckland murder case
Baby Leo's father charged with assaulting former trustee
Auckland teacher barred for having sex with student
Man arrested for theft of $10,000 worth of equipment from iMend-iT
Pompe disease sufferer calls for funding
Social media 'overreaction' after alleged abduction of Elm Park student
Sale of dream mansion heartbreaking
Four pulled from burning Auckland house
Family hope to take son back to Kosovo for reunion
Cathay Pacific fined for boarding unauthorised passenger on flight to New Zealand
Are our classrooms becoming overcrowded?


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Peter Werth was founded in Islington in 1975. As well as being a great year for us as a company, it was also a great year for cinema. 559 more words
If you need to know more check out the Keshe Foundation online. You can also search this blog - keyword - Keshe to get some background but essentially what he is saying is that the Keshe technology is going to halt future wars starting with a roadmap to peace. This starts on 21 June 2015. This will no doubt upset many who consider themselves elitists, rich, powerful and complacent, but as I have explained in a number of earlier postings, the real power can be seen, or felt with your given senses in nature and nature demands balance. Without it, there is nothing, its really that simple. So heres a link to the Free Ebooks from the Keshe Foundation. They may well be the most celebrated publications that humanity has ever produced. You may recall that I contacted Minister Joyce of National and most other notable politicians and parties when Keshe asked anyone to contact our politicians to send a team of scientists over to Belgium. While they also tried directly, my attempts to get anyone from all parties that I contacted proved futile. That said, it looks as though they will have no choice very soon. To halt corruption and usury sooner than anticipated and learn the truth hidden in the archives of history or in those that remain undamaged by the dumb and dumber, I wonder whom I refer too.


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The Bourne Legacy
A Nightmare on Elm Street
Prelude to a Kiss
Groundhog Day
All Rob Riley films
Movies.com, the ultimate source for everything movies, is your destination for new movie trailers, reviews, photos, times, tickets + more! Stay in the know with the latest movie news and cast interviews at Movies.com.
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The Style Gallery is a great new way for you to view, love, and share outfit photos. It's meant to showcase
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Coach Tour Dress in Houndstooth
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Orea Hotel Voronez - South Moravia (region)
This hotel has 3 restaurants. The bar/lounge is a perfect place to have a drink. Free WiFi is provided so you can check your in-box whenever you like.
Make sure, if it is summer, to request a room on the 9th or 10th floors - the only ones…
poor internet connection
Enter dates to check prices
Hotel Info: 1-844-302-2248from $55
- Standard Single Room
- Standard Double or Twin Room
- Superior Single Room
- Superior Double Room
Recommended hotels
At a glance
Key facts
Hotel size
- This hotel has 368 rooms
- This hotel is arranged over 10 floors
- Check-in time starts at 2 PM
- Check-out time is noon
- Express check-in/out
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
- Minimum check-in age is 18
Travelling with others
- Pets allowed *
- Restrictions apply *
- 2 per room
Extra people
- Roll-away beds available, charges may apply*
- Free WiFi in public areas
- Free WiFi in rooms
- Self parking (limited) *
- Accessible parking
- RV/bus/truck parking *
Other information
- Smoke-free property
- Resort fee included
In the hotel
- Free hot/cold buffet breakfast daily
- 3 restaurants
- Bar/lounge
- Room service
- Coffee/tea in the lobby
- Bicycle rentals nearby
- Hiking/biking trails nearby
- Sailing nearby
- Cross-country skiing nearby
- One meeting room
- Conference center
- 24-hour front desk
- Tours/ticket assistance
- Limo or Town Car service available
- Dry cleaning/laundry service
- Hair salon
- Luggage storage
- Number of buildings/towers - 1
- Year Built 1979
- Elevator/lift
- Safe-deposit box at front desk
- Television in lobby
- Disabled parking
- Accessible path of travel
- Braille or raised signage
- Accessible bathroom
- In-room accessibility
- Roll-in shower
In the room
- Minibar
- Hypo-allergenic bedding available
- Blackout drapes/curtains
- Turndown service
- Separate sitting area
- Private bathroom
- Deep soaking bathtub
- Free toiletries
- Hair dryer
- 66-cm flat-screen TV
- Pay movies
- Satellite TV channels
- Desk
- Free WiFi
- Daily housekeeping
- In-room safe
- Connecting/adjoining rooms available
Special features
DiningA La Carte - This fine-dining restaurant serves dinner only. Guests can enjoy drinks at the bar. A children's menu is available. Open select days.
Grill Bar Gurmet - This restaurant serves breakfast, lunch, and dinner. Guests can enjoy drinks at the bar. A children's menu is available.
Atrium - This restaurant serves breakfast only.
Orea Hotel Voronez - South Moravia (region)'s small print
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
Pet-friendly rooms can be requested by contacting the property at the number on the booking confirmation.
Only registered guests are allowed in the guestrooms.
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation.
Mandatory fees
The charges below are included in the total price displayed:
- Resort fee
Optional extras
Late check-out can be arranged for an extra charge of CZK 18
Rollaway beds are available for CZK 19.00 per day
Pets are allowed for an extra charge of CZK 11.00 per pet, per night
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.


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Explore the personal stories of Syrian refugees in Lebanon
Ghana's mixed fortune as a dumping ground for e-waste
16 Aug 2011 20:25 GMT | Latin America, El Salvador
Al Jazeera interviews Mauricio Funes, El Salvador's president, about the dangerous and growing drug trafficking situation in his country and the region.
Funes says that gangs have evolved from loose-knit groups of people without many options to more advanced "task forces in the service of organised crime", which are being used by international drug cartels.
He also discusses the "regional strategy" of confronting cartels, which often have a higher operating budget than several Central American countries combined.
More than $100bn is spent annually on drug trafficking in Central America, compared to El Salvador's annual budget of $4bn.
Source: Al Jazeera
Salvadorian president says gangs in his country are being co-opted by Mexican drug cartels.
Business & Economy, Latin America, El Salvador, Mexico
Mexican gangs suspected of managing the increased smuggling of tonnes of cocaine through country.
Business & Economy, Latin America, Bolivia, Colombia, Honduras
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The United States is leading secret negotiations with 11 other countries over the Trans-Pacific Partnership Agreement.
Asia Pacific, New Zealand, Health
An alarming number of young UK offenders with criminal records were previously in the care of local authorities.
Europe, Child rights, Law
Caught in cycle of poverty feeding off the informal labour market, Mexico poor grow old on the job, have no retirement.
Human Rights, Latin America, Mexico
Forgiveness, reconciliation and an arms embargo are key ingredients for peace in South Sudan, says Bishop Paride Taban.
War & Conflict, Africa, Sudan
Taliban sources tell Al Jazeera that Mullah Akhtar Mansoor is new leader of the group, confirming death of Mullah Omar.
Taliban, Afghanistan
Cairo court adjourns long-running retrial of Peter Greste, Baher Mohamed, and Mohamed Fahmy until August 2.
Media, #FreeAJStaff, Egypt, Middle East
Eyal Weizman explains architecture's key role in the Israeli occupation of Palestine and the evolution of urban warfare.
Human Rights, Israel, Palestine
There is a unique and dangerous commerce system at work in Amazonia, where children risk their lives for a few pennies.
Business & Economy, Latin America, Brazil
We expose the dirty secrets behind Australia's fresh food industry and the widespread exploitation of foreign workers.
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The devastating impact that war and living under the constant threat of drones has had on the people of Afghanistan.
War & Conflict, Health, Afghanistan


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by Casey Ball, The Sherwin-Williams Company
A master of Italian plasters offers a plain English guide to the materials
The PaintSquare Pro Video Series: An archive of webinars hosted by PaintSquare.com in cooperation with SSPC
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We must center mags party around a heavily decorated tiffany themed table....possibly using paper bkcground if needed! Hawaiian-themed girl birthday party. Absolutely adorable!!!!
Summer birthday-So cute to see this birthday for two girls because this will probably be us someday with my girls' bdays going to be so close!
luau party--- could make this banner from craft paper. Add Chinese lanterns and tissue paper flowers.
cupcake party - How much fun would this be - kids party or ladies night, either could be equally as fun!
hulu cans. This would be cute for a summer party. Guests can decorate their cups so they know it is theirs. Would even work for wine glasses.
Welcome summer with this adorable Aloha Summer Party! Love the candy kabobs the aloha cookies, the drinks, and the colors!


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Strong negotiation and legal drafting skills. Strong leadership, interpersonal, negotiation and legal skills....
Aug 3 - United States
Do you have another job, legal or otherwise? Hire Counsel is proud to be a 100% employee owned company through the HCMC Legal, Inc....
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Legal background or familiarity with legal issues and terminology is preferred. Candidates with a legal background or familiarity with legal processes are...
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Prime Legal has a need for a LEGAL SECRETARY to support attorneys in an elite law firm located. Provide support to attorneys on a variety of non-litigation...
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Corporate Attorney with 1-3 years of business experience
Albany office is seeking an associate for corporate department. Candidate should have 1-3 years of experience working on business and transactional matters.
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Associate Attorney with 1st chair family law experience
Albany office seeks associate attorney with 1-2 years of litigation experience. The candidate will manage family law cases from beginning to end. Should have 1st chair family law experience. Must be licensed to practice law in the state of New York and passed the Bar Exam on the first attempt.
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The Top 10 In Action Sports
01Tragedy in Colorado: Mountain Biker Killed at Enduro World Series in Colorado
02Robby Naish: The Man Who Conquered The Ocean One Competition At A Time
03"Seven Went Up, Only Three Came Down": How The Unsolved Mystery Of The Matterhorn Keeps Our Fascination Alive
04The Indestructibles: New TV Show Coming Soon To Dave, Sponsored by G-SHOCK
05Swapping The Streets of London For Cornish Surf Is Easier Than You Think
06Mad Descents & Lunar Landscapes: Incredible Shots from One of Europe's Best MTB Destinations
07Eccentric Adventures Episode 4: We Risked Life And Shin At The Cotswold Olimpicks
08Why Do We Travel?
09Going Against the Brain: How Ski and Snowboard Head Injuries Re-Shaped Two Young Lives
10#JoinTheRide With Animal And Win A Trip Of A Lifetime
Moto Cribs - Ryan Hughes
Part 2 of our look at Rynoland. In this installment we check out Ryno's Garage. And what a garage it is as well. Many of us would be happy with a house half as good, Ryno's Garage has everything a young aspiring Motocross racer could ever need. Unlike many people you see on MTV Cribs Ryno's Gym certainly aint for show. Let Ryno Guide you round his humble abode. Enjoy and dream.
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etching, 5x7, plate signed
Etching, 1882, 7 1/4 x 9 1/2 inches, plate signed
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Gouache, attributed to Giovanni Giani, circa 1890, image size 12 5/8 x 19 inches in period frame.
Etching, pub. June 15, 1896, by Dreighton, Trafalgar Square, image size 3 5/8 x 6 1/4 inches
This drawing by Dexter Dawes measures 21 1/4 x 14 1/2 inches and is dated "July 7, 1929" on the lower margin. Dawes was born in Englewood, NJ and went on to study at New York City's Art Student League. He summered in Marlboro, NH surrounded by beautiful gardens with views of Mount Monadnock which became the inspiration for many of his lithographs and drawings. He belonged to a number of associations including the National Arts Club


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This property allows you to book online with a credit card. After submitting a reservation request, the owner or manager has 24 hours to accept, at which time your card will be charged and you will receive an email confirmation
Other areas nearby to Colorado Springs:
Recent Colorado Springs reviews
"Owners were very friendly and easily reachable at all times. Helped provide a high chair and 2 pack'n'plays which made traveling with children so much easier. Property was clean and comfortable. Good location in Colorado Springs and it was easy to get to any place in the area. Would recommend"Guest: Voytek S. Date of Stay: June 2015 Review Submitted: June 18, 2015View listing
"Accommodations lovely, clean and convenient to Colorado College, The Incline, Garden of the Gods and beyond. Emily was very helpful, responding quickly to every communication. We found her home to be a very peaceful retreat after hiking, running, and following a variety of events celebrating our son's graduation. We cooked breakfasts and dinners and found everything we needed to prepare delicious meals 'except' a sharp knife. Within hours after our arrival the home manager phoned to make sure we were settled. He asked if there were any concerns. Being a VRBO owner myself, I shared that the chef knife was dull and barely cut butter. I also said very sincerely 'no worries, we will deal with it, there are other smaller knives.' Nevertheless, within 18 hours a new, sharp chef knife appeared! I was impressed! The sounds and views are spectacular. I would definitely return and recommend to others looking to rent in Manitou Springs/Colorado Springs area."Guest: Kathy M. Date of Stay: May 2015 Review Submitted: May 24, 2015View listing
"Our family stayed at The Cottage on the Greens to celebrate a milestone birthday. The home is beautiful, and so well suited for gathering and connecting with others. We found ourselves in small groups gathered on the patio, in the living room, and in the family room. We cooked and had a family meal around the dining room table, and were delighted to find the kitchen stocked with every kind of pot, pan, dish, and utensil that we needed. Steve and Cathy were very gracious, and did all they could to assure that we had a good experience. We had a great experience, and highly recommend this property."Guest: PasKat Date of Stay: June 2015 Review Submitted: July 19, 2015View listing
"This is a great location to rent, particularly for those like us engaging graduation activities at the USAF Academy. We had the additional complication of having our pets along, so this pet-friendly place was ideal. The location is very private, and yet getting to town quickly was simple, and activities at the Academy were 15-20 minutes away maximum! We were able to host many people at our post-graduation get-together and there was ample parking and room for all to comfortably visit! The owners kindly supplied us with extra chairs and a couple of picnic tables to improve our party preparations. We thoroughly enjoyed our stay, and it felt like home to us!"Guest: Rhonda D. Date of Stay: May 2015 Review Submitted: June 11, 2015View listing
Featured Destinations: Breckenridge Lodging, Lake Nacimiento, Smoky Mountain Cabin Rentals, Black Butte Ranch


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1. Some renderings for a potential new Major League Soccer stadium on Manhattan's Pier 40 leaked onto Reddit yesterday.
(Even better, they're legit.)
5. Here's an overhead view of the current area. Dare to dream.
6. After all, you can't beat that view.
Flickr / Creative Commons / Kevin Harber / Via Flickr: 16151021@N00
via Reddit
Preview Your Response
Here Are The Top Stories
- The death penalty should still be considered for Colorado theater shooter James Holmes, a jury decided.
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- California Gov. Jerry Brown called for a state of emergency as wildfires burned thousands of acres by Sunday and forced hundreds of evacuations.


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(Photo by Janette Beckman)
UPDATE: Congrats to all our winners! If you have yet to pass along your govt name to us (either here privately in the comments section or via email) please do so asap so you may claim your tickets for tonight's show at the venue box office. Otherwise we will simply leave your comments author ID & email at the venue. Enjoy the show! Discount Oakley Sunglasses
Hey, good people of New York City! Come celebrate the Red Bull Music Academy World Tour 2011 tomorrow - Tuesday, September 27th - as the "Five Out of Five, NYC" series continues at the Paradise Theater in the Bronx with none other than Slick Rick. That's right, The Ruler is back. Everybody is invited to the free Chairman Mao-moderated discussion tomorrow afternoon with MC Ricky D and special guest D-Nice of BDP as they recount the making of the classic Fake Oakleys The Great Adventures of Slick Rick LP. But that's not all. The first 20 folks who can answer the following question correctly will EACH WIN A PAIR OF FREE tickets to Slick Rick's performance later that night.
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