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Benign sinonasal masses presentation & management-1
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Transcript of "Benign sinonasal masses presentation & management-1"
1. DR Kamlesh Dubey AIIMS NEW DELHI
Epithelial: Sinonasal gland tumors Pleomorphic adenoma Myoepithelioma Oncocytoma Schneiderian papilloma Warts Neuroectodermal tumors: Paraganglioma Schwannoma Neurofibroma
Bone & Cartilage tumors: Osteoma Osteoid osteoma Fibrous dysplasia Ossifying fibroma Osteoblastoma Ameloblastoma nasal chondromesenchymal hamartoma giant cell lesion giant cell tumor Chondroblastoma chondroma
Displaced neural lesions(ectopic site): Nasal glioma Pituitary adenoma Soft tissue tumors: Vascular tumors: Juvenile nasopharyngeal angiofibroma(JNA) Hemangioma Hemangiopericytoma Fibrous : Nasal fibroma Muscle tumors: Leiomyoma Rhabdomyoma
In 1600s C. Victor Schneider demonstrated nasal mucosa : Produces catarrh not csf Ectodermal origin 1854 Ward first described Schneiderian papillomas (SPs) of the nose (i.e., sinonasal papilloma) Kramer and Som classified SPs as true nasal neoplasms and described them as true papillomas Ringertz was the first to identify the tendency of SPs to invert into the underlying connective tissue stroma, which differs from other types of papillomas
Fungiform: 50% , nasal septum Cylindrical: 3%, lateral wall/sinuses Inverted: 47%, lateral wall
arise in the nasal septum " exophytic growth pattern " do not grow down into the underlying normal stroma " associated with human papillomavirus " do not have a tendency to recur >57% HPV DNA positivity
ragged, beefy appearance and " histologically : composed of columnar cells " pink cytoplasm " nuclei are oval or round " many areas of mucin cysts " actually act very similar to inverted papillomas More chances of malignancy
The US National Cancer Institute has defined inverted papilloma as a type of tumor in which surface epithelial cells grow downward into the underlying supportive tissue Inverted papillomas arise from the Schneiderian membrane, which is an invagination of the olfactory ectoderm that occurs during the fourth week of embryonic development. The mucosa creates a transitional zone between the endo-dermally derived respiratory epithelium of the nasopharynx and keratinizing squamous epithelium with the nasal vestibule
Locally aggressive sinonasal tumor " Arises from nasal respiratory epithelium,, which undergoes metaplastic change and proliferation " characterized best by its local invasion, tendency for recurrence, and association with malignancy
Schneiderian papilloma Schneider papilloma Inverting papilloma, Inverted papilloma Ringertz tumor epithelial papilloma Transitional cell papilloma
Benign/intermediate 0.5% to 4% of sinonasal tumor Site of origin Age/Sex: male, 5-6th decades
Exophytic (tree) Inverted (nodule)
appearance of the epithelium inverting into the stroma with a distinct and intact basement membrane that separates and defines the epithelial component from the underlying connective tissue May be associated with: Atypia Ca in situ Carcinoma: Scc, transitional cell carcinoma, adenocarcinoma Mucoepidermoid ca, verrucous ca
Etiology : association between common papillomas and the human papillomavirus (HPV) " HPV types 6 and 11 Kusiak and Hudson described the presence of intracytoplasmic and intranuclear inclusion bodies in SPs air pollution and industrial carcinogens " male: female ratio of 3:1. . " average age was 54.3 years " most common in the fifth and sixth decades Respler DS, Jahn A, Pater A, Pater MM. Isolation and characterization of papillomavirus DNA from nasal inverting (schneiderian) papillomas. Ann Otol Rhinol Laryngol. Mar- Apr 1987;96(2 Pt 1):170-3 Weber RS, Shillitoe EJ, Robbins KT, Luna MA, Batsakis JG, Donovan DT, et al. Prevalence of human papillomavirus in inverted nasal papillomas. Arch Otolaryngol Head Neck Surg. Jan 1988;114(1):23-6
Grossly :: exophytic and polypoid " more vascular than an inflammatory polyp " gray to pink " frond--like projections that extend from the main bulk of the specimen " Epithelium inverts into underlying stroma
epithelium distinct from the respiratory (pseudostratified ciliated columnar) mucosa of the sinonasal cavity -- may be squamous, transitional or respiratory -- epithelium proliferative and thickened -- lacks mucus--secreting cells and eosinophils
Tendency to recur Destructive capacity to surrounding structures Propensity to be associated with malignancy
They are associated with malignancy, 5% to 15% malignancy rates are most generally accepted. Inverted papillomas are more commonly associated with squamous cell carcinomas. There are four types of association: Metachronous squamous cell carcinoma. Carcinoma in situ within the IP Synchronous lesions Malignant transformation
unilateral nasal obstruction (58%) " epistaxis (17%) " nasal drainage (14%) " bilateral nasal obstruction (12%) " nasal mass (9%) " sinusitis (9%) " headache " diplopia " facial numbness " facial swelling " anosmia
Krouse summarized from 1967 to 1997 primary sites of IP " lateral nasal wall (82%) " maxillary sinus (53.9%) " ethmoid sinus (31.6%) " septum (9.9%) " frontal sinus (6.5%) " sphenoid sinus (3.9%)
KrouseType 1: Tumour totally confined to the nasal cavity. The tumour can be localized to one wall or region of the nasal cavity, or can be bulky and extensive within the nasal cavity, but must not extend into the sinuses or into any extranasal compartment. There must be no concurrent malignancy. Type 2: Tumour involving the ostiomeatal complex, and ethmoid sinuses, and / or the medial portion of the maxillary sinus, with or without involvement of the nasal cavity. There must be no concurrent malignancy. Type 3: Tumour involving the lateral, inferior, superior, anterior, or posterior walls of the maxillary sinus, the sphenoid sinus, and / or the frontal sinus, with or without involvement of the medial portion of the maxillary sinus, the ethmoid sinuses, or the nasal cavity. There must be no concurrent malignancy. Type 4: All Tumours with any extranasal / extrasinus extension to involve adjacent, contiguous structures such as the orbit, the intracranial compartment, or the pterygomaxillary space. All tumours associated with malignancy
Han et al. Group 1: Tumour involvement limited to the nasal cavity, lateral nasal wall, medial maxillary sinus, ethmoid sinus, and sphenoid sinus. Group 2: Same as group 1 except that tumour extends lateral to the medial maxillary wall. Group 3: Tumour extends to involve the frontal sinus. Group 4: Tumour extends outside the sinonasal cavities (i.e., orbital or intracranial extension).
Kamel et al. Type 1: Tumour originating from the nasal septum or lateral nasal wall. Type 2: Tumour originating from the maxillary sinus. [This classification focuses on origin and not size / extent of tumour-does not analyze frontal sinus separately]
Oikawa et al. T1: Tumour limited to nasal cavity. T2: Tumour limited to ethmoid sinus and / or medial and superior portions of maxillary sinus. T3: Tumour involves lateral, inferior, anterior, or posterior walls of maxillary sinus, sphenoid sinus, or frontal sinus. T3-A: without extension to frontal sinus or supraorbital recess. T3-B: involving frontal sinus or supraorbital recess. T4: Tumour extends outside sinonasal cavities (orbital or intracranial extension) or associated with malignancy
cannady et al. Group A: Inverted papilloma confined to the nasal cavity, ethmoid sinuses, or medial maxillary wall. Group B: Inverted papilloma with involvement of any maxillary wall (other than the medial wall), or frontal sinus, or sphenoid sinus. Group C: Inverted papilloma with extension beyond the paranasal sinuses
Typical presentation : unilat.polyps " antral choanal polyp " allergic fungal sinusitis " squamous cell carcinoma " adenocarcinoma " esthesioblastoma
" CT and MRI are the common modalities " CT is the most widely performed study " bony changes " bowing of the bones near the soft tissue mass
convoluted cerebriform pattern on T2- or enhanced T1-weighted images suggests inverted papilloma as a histologic diagnosis Necrosis in a mass with such an appearance strongly suggests coexistent carcinoma columnar pattern is a reliable MRI indicator of IP and reflects its histological architecture (positive predictive value of 95.8%) combination of this finding with the absence of extended bone erosion allows for the confident discrimination of IPs from malignant tumors
Surgery " Radiation therapy
Surgical approaches: • Headlight intranasal polpectomy • Caldwell Luc procedure • Medial maxillectomy • Lateral rhinotomy • External procedures of the frontal sinus • Endoscopic intranasal polypectomy • Endoscopic maxillary antrostomy/ethmoidectomy, Sphenoidotomy • Endoscopic medial maxillectomy • Median drainage procedure to gain access to the frontal sinus
Stammberger reported the first purely endoscopic approach for treatment of SP, which was performed in 15 patients in 1981 Most reported endoscopic resections have involved piecemeal resection of the inverting papilloma followed by piecemeal resection of the lateral nasal wall
Contraindicated in: massive involvement of the mucosa of the frontal sinus and/or of a supraorbital cells intradural extension or transorbital extension concomitant presence of a malignancy presence of abundant scar tissue from previous surgery
Key point: to dissect the involved mucosa along the subperiosteal plane to drill the underlying bone whenever required by imaging and/or intraoperative finding Extent surgery: site of the lesion area of mucosa involved by the lesion
Initially via transnasal resection: 50-80% recurrence Medial Maxillectomy via lateral rhinotomy: Gold Standard 10-20% Endoscopic medial maxillectomy: Key concepts: Identify the origin of the papilloma Bony removal of this region Recurrent lesions: Via medial maxillectomy vs. Endoscopic resection 22%
Predisposing factors: Tumor location Histology Multicentricity Method of removal Length of follow up Main factor: thoroughness of removal
Bielamowicz et al: found a statistically significant difference between the recurrence rates in patients treated with medial maxillectomy (20%) versus those treated with a conservative resection (47%). Mirza et al: found that recurrence rates in 63 case series was 12.8% for endoscopic procedures (n = 484), 17.0% for lateral rhinotomy with medial maxillectomy (n = 1025) 34.2% forlimited resections such as nasal polypectomy (n = 600)
Surgical approach Recurrence/case series Percentage Mean –follow up Endoscopic resection 173/1190 14.5% 3 years 1month Lateral rhinotomy with medial maxillectomy 207/1239 16.7% 5 years 2 month Limited resection such as nasal polypectomy 208/606 34.4% Inadequate
Classic entities: Osteoma Fibrous dysplasia Ossifying fibroma
Definition : Benign condition in which normal bone is replaced by fibrous connective tissue due to a defect in osteoblast differentiation and maturation
Pensler et al: investigated cultures derived from the involved bone in two children with MFD and in one child with Albright's syndrome showed a two- to threefold increased level of estrogen and progesterone receptors by radioimmunoassay and immunocytochemical assay concluded that estrogen may play a major role in the bony metabolism of FD
Actual cause: set of mutations in the GNAS1 gene located on chromosome 20q13.2 that normally codes for the alpha subunit of the G- protein
Genetically based developmental anomaly Defect in osteoblastic differentiation and maturation replacement of normal bony tissue by fibrous tissue of variable cellularity and immature woven bone Histology: slow replacement of medullary bone by abnormal fibrous tissue with different stages of bone metaplasia
Incidence not known Females > males No race predilection Initial symptoms manifest age 3-15 Not heritable Questionable genetic transformation Malignant transformation in < 1%
Cystic (21%) - Radiolucency surrounded by solid rim Sclerotic (23%) - Dense and homogenous Mixed (56%) - "Ground glass appearance"
Monostotic - Most common - 25% involve head and neck Polyostotic - 15% of cases - 50% involve head and neck
Eosinophilic granuloma Nonossifying fibroma Bone hemangioma Hyperparathyroidism Paget's disease Brown's tumor Aneurysmal bone cyst
Polyostotic fibrous dysplasia Café-au-lait spots Endocrinopathology: - Hyperthyroidism - Precocious puberty in females
" fibrous dysplasia characteristically has a ground glass appearance on CT images. . It generally presents in younger patients (children and adolescents), and its growth rate may decrease or stop after puberty
Surgery: intended to relieve symptoms : visual impairment due to compression of the optic nerve to correct aesthetic deformities but not to remove the entire lesion Radiotherapy is contraindicated Medical treatment : bisphosphonates (i.e., pamidronate) with success in patients with extensive lesions associated with significant disfigurement and pain Octreotide, anti hyperthyroid agents, antiandrogens
a true benign neoplasm occurs in the third and fourth decades of life preferentially in black women Manifestation: space-occupying lesion in the nasal cavity evident at endoscopic examination
Aetiology: so far not been clarified. Trauma has been reported to play a major role in the development of OF, especially of the cemento-ossifying fibroma Histology: demarcated margins consisting of fibrous tissue with varying amounts of mineralized or calcified psammomatoid bodies
present between the second and fourth decades of life female incidence is more frequent than male incidence a male to female ratio of 1:5 Ossifying fibroma of the mandible is usually asymptomatic Depending on its extent: facial pain Swelling nasal obstruction Rhinosinusitis ocular symptoms
Differs from common OF by age (younger), location (maxilla) & biologic behavior (sometime aggressive and/or recurrent). Two microscopic types; trabecular & psammomatoid; age at diagnosis 11 and 22 respectively. Maxilla often with impingement on sinuses, orbit, nose and cranium.
Treatment of choice is dependent on the site of tumour location Tumours invading the midfacial portion and the sinonasal tract: more aggressive behavior need surgical resection surgical treatment : requires radical resection/when possible a total removal of the tumour: high rate of relapses aggressive behavior of recurring tumors :with local destruction and potential invasion of adjacent vital structures
Since OF is very rare, larger series on pure endonasal resection are not reported In case reports, some authors have achieved tumour resection via an endoscopic approach Draf et al. (480) reported on endonasal microendoscopic resection of four OF without any complications OF with a large extension, most authors recommend a combined approach including craniofacial resection
Introduction: Sinonasal osteomas are common entity seen in patients. Rhinosinus osteomas are commonly asymptomatic and are incidental findings on imaging studies. History: Viega was the first to document sinus osteoma in 1506. In 1733, Vallisnieri described frontal sinus osteoma that protruded into the brain. Epidemiology: Ostomas are the most common benign tumors of paranasal sinuses. This condition is more common in males. It is common in patients between their second and third decades of life.
Three accepted theories of etiology of osteomas are: 1. Developmental 2. Traumatic 3. Infectious Developmental : Adult tissue contains embryonic remnants usually remaining dormant Could be the reason for occurrence near frontoethmoidal suture lines
Traumatic : Inflammatory process as the initiating force Bony trauma could be the root cause Could account for male preponderance Infectious : This theory suggests that ostietis resulting from chronic infections could lead to osteoma formation in paranasal sinuses.
possible aetio-pathogenetic role of traumatic and inflammatory factors: Moretti A, Croce A, Leone O, D'Agostino L. Osteoma of maxillary sinus: case report. Acta Otorhinolaryngologica Italica2004;24(4):219-22 Naraghi M, Kashfi A. Endonasal endoscopic resection of ethmoido-orbital osteoma compressing the optic nerve. American Journal of Otolaryngology 2003;24(6):408-12. Sayan NB, Ucok C, Karasu HA, Gunhan O. Peripheral osteoma of the oral and maxillofacial region: a study of 35 new cases. Journal of Oral & Maxillofacial Surgery 2002;60(11):1299-301.
Fu and Perzin classification: 1. Ivory / compact osteoma: Otherwise also known as eburnated osteoma. In this type of osteoma the bone is very dense and lacks haversian canals. These osteomas develop from membranous elements. 2. Osteoma spongiosum: Also known as mature osteoma is composed of softer bone. This type of osteomas are known to arise from cartilaginous elements. These osteomas have little medullary component containing fibrofatty tissue. 3.Mixed
Behavior: Osteomas are very slow growing and are mostly asymptomatic. They always stay benign and don't recur after excision. The growth rate of osteomas of the paranasal sinuses Koivunen P et.al. Clin. Otolaryng Allied Sci 1997Apr;22(2):111-4 mean growth rate: 1.61mm/yr range 0.44 to 6.0 mm/yr Common sites: 95% osteomas in the sinonasal region arise from the frontoethmoidal region. 80% of osteomas in the sinus region arise from the floor of frontal sinus
Plain sinus radiographs are adequate for detecting osteomas of paranasal sinuses.
most commonly localized to the frontal sinus " slow growing and well circumscribed " symptoms attributable obstruction of the drainage pathway of nearby sinuses " On endoscopy : firm masses with a smooth mucosal covering
Wait ,watch n scan Surgery: Indications: Rapid growth of tumor Symptomatic patients with chronic rhinosinusitis due to tumor obstruction Massive headache Facial deformity Smith & Calcaterra et al: Surgery if tumor occupies more than 50% of frontal sinus Approaches : Endonasal External Combined approach
Frontoethmoidal and intraorbital osteomas: exploring the limits of the endoscopic approach (Turri-Zannoni et. al Arch. Otolar Head Neck Surg.2012 May) Conclusion: The size of the osteoma, far lateral extension of the tumor in the frontal sinus beyond the lamina papyracea, and intraorbital involvement are no longer absolute contraindications for purely transnasal endoscopic resection. What is important is that the surgeon should not be dogmatic but rather be ready to change his or her mind during surgery, shifting to an external approach when required.
Exceptions: scarring of the frontal recess Distortion from previous surgery, very advanced disease and associated malignancy
Displaced/Ectopic tumors
made of neuroglial elements consisting of glial cells in a connective tissue matrix with or without a fibrous connection to the dura " no fluid filled space connected to the subarachnoid space
" present as a red or bluish lump at or along the nasomaxillary suture, or as an intranasal mass. " firm, noncompressible " not increase in size with crying, and do not transilluminate " not enlarge with bilateral compression of the internal jugular veins (Furstenberg test) " associated with a widened nose or with hypertelorism secondary to growth of the mass
arise from the lateral wall of the nose or less often from the nasal septum. " 60%extranasal " 30% intranasal " 10% are both " 15% are connected to the dura " intranasal type associated with dural attachment (35%) > extranasal type (9%).
development similar to nasal dermoids. " Abnormal closure of the fonticulus Develop from extracranial rests of glial tissue Abnormal closure of fonticulus nasofrontalis, possibly encephaloceles which have lost CSF connection tissue being left extracranially. " not always an intracranial connection to a glioma
Bluish, soft, compressible, transilluminate, pulsatile Enlarge with crying Positive Furstenberg test (bilateral compression of internal jugular veins) Originate medially in the nose May have associated CSF leak
4% are found within the paranasal sinuses Schwannoma Neurofibroma Treatment via surgical resection When associated with Von Recklinghausen's syndrome: more aggressive (30% 5yr survival).
Shrinivas SC, Deshmukh S, Pawar V, et al. Case Study of Clinicopathological correlation of benign sinonasal masses. World Articles in Ear, Nose and Throat 2012;5(1) :showed nasal schwannoma accounting for 2.4% of benign nasal masses Vaideeswar P et al : schwannoma formed 2.5% (three cases) of all Sinonasal tumors
slowly growing mass arise more frequently from the ophthalmic and maxillary divisions of the trigeminal nerves also originate from sympathetic fibers of the carotid plexus or parasympathetic fibers of the pterygopalatine ganglion Symptoms depend on the location : progressive nasal obstruction ± epistaxis anosmia / hyposmia headache facial swelling and proptosis
Macroscopically: well-delineated but nonencapsulated globular firm to rubbery yellow-tan mass Histologically: cellular Antoni A areas with Verocay bodies hypocellular myxoid Antoni B areas Immunocytohistochemistry: strongly and diffusely immunoreactive for S-100 protein
Mey KH et al in a case series of five nasal schwannoma Buob et al in a series of nasal schwannoma cases Unlike other areas nasal schwannoma is usually not encapsulated According to these authors this peculiarity could be explained by the development of these tumours from Sinonasal mucosal autonomic nervous system fibres which are devoid of perineural cells similar to the case of gastric Schwannoma
Immunohistochemistry : Positive stains: S100 Negative stains: EMA, CD34, Ki-67/MIB1 (1- 5%) Treatment: radical surgical resection; no recurrence or metastases
Rare, frequently misclassified Mean age 48 years, range 13-88 years; no gender preference Usually primary intranasal or paranasal mass; may also be an intracranial tumor invading sphenoid or frontal sinuses Primary extracranial tumors have a good prognosis; intracranial lesions invading into upper respiratory tract are difficult to excise Positive stains: EMA, vimentin Negative stains: S100 (usually)
JNA Hemangioma
The term hemangioma has traditionally been used to describe a variety of developmental vascular anomalies. Currently, hemangiomas are considered to be benign tumors of infancy that are characterized by a rapid growth phase with endothelial cell proliferation, followed by a gradual involution. Most cannot be recognized at birth but make their appearance in most instances during the first 8 weeks of life. Vascular malformations are structural anomalies of blood vessels without endothelial proliferation and are present at birth and persist throughout life.
These lesions are present from birth and persist throughout life. As with hemangiomas, these lesions tend to darken with age. Low-flow venous malformations typically have a blue color and are easily compressible. Arteriovenous malformations are high-flow lesions that result from persistent direct arterial and venous communications. A palpable thrill or bruit is often noticeable and the overlying skin typically feels warmer to the touch.
Hemangiomas are the most common tumors of infancy. They have a female gender predilection (3:1) and are most common in the White population. 60% of the hemangiomas occur in the head and neck region with 80% of them occurring as single lesions. Multiple lesions may be part of a syndrome. About 50 % of all hemangiomas will show complete resolution by 5 years of age.
Types : depending on size of vessels Capillary Cavernous Mixed Multifocal angiomatosis: when multiple or affecting a large segment of the body
frequently occur in the head and neck region, • uncommon in the nasal cavity and paranasal sinuses, • cavernous and capillary types have been reported in the sinonasal region, • represent less than 20% of all benign nasal cavity tumors, • 80% arise from the nasal septum (Kiesselbach area), 15% arise from the lateral wall of the nasal cavity. • originate from the soft tissues of the nasal cavity • also occur in bones of the inferior or middle turbinate (> 1% bone tumors). • cavernous hemangiomas usually do not present until adulthood (adults) • in both sex with equal frequency, • incidence peaks in the 4th decade of life.
Trauma, viral oncogenes, inflammatory conditions and the production of angiogenic growth factors may play a role in the development hyperplastic, neovascular response to an angiogenic stimulus with imbalance of promoters and inhibitors The occurrence and growth of these lesions during pregnancy may be related to increased blood volume or hormonal influences. Cavernous hemangioma in adults not undergo spontaneous involution such as head and neck hemangioma in the paediatric population
Clinical presentation and symptoms: • epistaxis and/or hemoptysis • enlarging lesion in the nasal cavity Macroscopy: Red-blue, soft, spongy mass or nodule
Differential Diagnosis • Antrochoanal polyp •Inverted papilloma • Hemangiopericytoma • Esthesioneuroblastoma Treatment and prognosis: • surgical resection via transnasal endoscopic approach, • for extensive lesions: preoperative selective embolization, • radiation therapy: for unresectable or inaccessible lesions, • no recurrences after surgical removal have been reported.
misnamed; they are neither infectious nor granulomatous usually occurs in children and young adults solitary, glistening red papule or nodule that is prone to bleeding and ulceration
precise mechanism for the development of pyogenic granuloma is unknown Postulated: Trauma, hormonal influences, viral oncogenes, underlying microscopic arteriovenous malformations, the production of angiogenic growth factors, and cytogenetic Trauma: Nose picking, nasal packing, cauterization, shaving/hair removal, and nonspecific microtrauma Isolated cases: Sturge-Weber or von Hippel- Lindau syndrome
Curettage Cryotherapy Excision: with preop ± embolization EES LASER Sclerotherapy
Cumming's 5th edition Scott-Brown's 7th edition Rhinology journal(Official Journal of the International and European Rhinologic Societies) European Position Paper on Endoscopic Management of Tumours of the Nose, Paranasal Sinuses and Skull Base(Professor Stammberger, Professor Lund) Pubmed medscap
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17 of 23 people found the following review helpful
Warning: If you love etymotic er4p or er6i you will HATE these.,
Verified Purchase(What is this?)
This review is from: Etymotic MC5 In-Ear Earphones - Black (Electronics)
I have and adore etymotic er4p and er4s. I had and semi-adored the slightly cheaper er6i too. Unfortunately my er6i's met with an accident and when i went to find another pair i discovered they were discontinued and that etymotic had replaced them in their range with these, the mc5's. In fact if you go to the er6i page it tells you that these are the newer version of the er6i's. Great! thought i. And bought a pair without hesitating.
When i got them .... omg. Hideous. Gone are the crystal clarities ety are known for and in is mud and mess and in-distinction and so much middle and fuzzy bass that you think you're wearing shure or klipsch. This isn't audiophile; it sounds like the mid 1970s.
If you like what ety used to do ... avoid these like the plague. I hate them.
Tracked by 1 customer
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Showing 1-6 of 6 posts in this discussion
Initial post: 3 Oct 2011 12:08:17 BDT
M. A. Harwood says:
Just wondering if you got a rip-off copy?
In reply to an earlier post on 5 Oct 2011 06:48:22 BDT
Do Amazon sell rip-off copies? No. What I got was the real thing and they aren't a patch on the er6i/s. Ety should stick to what they do (did?) best rather than trying to sound like shure and co..
Posted on 2 Aug 2012 17:50:05 BDT
Androgeos says:
Rubbish review. Luckily I ignored this useless review and bought these anyway. I am a long time owner of a pair of ER6i which I adored. I also own a pair of Shure SE530, which cost 4 times as much as these.
I've had these MC5 for only 1 day and I already adore them. I'm seriously considering selling my SE530, as these are almost as good. Oh, and they are a CLEAR improvement over the ER6i.
Beautiful bass, tight and similar to the one I get with my Dynaudio Focus speakers. Great clarity, these blew me away. They even isolate better than the Shure, using the included flanges.
I will write a full review soon, in the meantime, I think you either didn't insert them properly or you got fake ones.
In reply to an earlier post on 2 Aug 2012 20:56:03 BDT
Last edited by the author on 2 Aug 2012 20:57:14 BDT
If you had read my review and my above comment correctly, Androgeo, you would be aware of the fact that I did not get "fake ones"; i bought them from Amazon and have tried both my own pair and two other pairs of them with the same unsatisfactory result. And I did not insert them incorrectly. These earphones colour the sound. They do not "present it, uncluttered". As such, they are not audiophile quality. I find them significantly inferior to the ER6i which in turn I find inferior to ER4s. I too have owned SE530s and dislike them. Which is why I dislike these MC5s as they sound like an inferior variety of Shure rather than the crisp clear Etymotic presentation I had come to know and love.
Horses for courses, Androgeo. It is very rude of you to call my review a "rubbish review" simply because your opinion of what is and is not "good sound" differs from mine. As I said, if you like the Shure sound you will like the MC5s. I do not. Therefore I do not like the MC5s and regret Etymotics change of aural direction.
In reply to an earlier post on 3 Aug 2012 01:45:10 BDT
Last edited by the author on 3 Aug 2012 01:51:17 BDT
Androgeos says:
You describe the bass as muddy and messy. I thought the exact opposite: Over the past years I have tried several pairs of IEMs (Klipsch, Shure, Etymotics, Atrio, Phonak, Denon, Sennheiser). The bass on these MC5 is incredibly detailed, not boomy at all, tight.
I've heard the ER4p and they are better - for the price they must be. However these are amazing value and amazing quality for what you pay. No other IEMs I've tried in the price range or even for twice as much have had such an *uncoloured* presentation. And the highs are fantastic in my experience: the cymbals on my Blue Note XRCD24 FLAC rips have never sounded better on similarly priced iems. That includes the ER6i. Again, the bass on acoustic recordings is excellent, textured, tight. On the other hand, some poorly mastered over-compressed cds I own sound poor through these. These are definitely not for brickwalled hip-hop, rock and dance music by the way.
Probably the geometry of your ear canal is very different from mine, hence your opposite findings. It is a possibility that you are not able to get a good fit with these. Also what are your sources and how do you encode your music? Apologies for asking but these are very much "garbage in, garbage out" iems.
Bottom line, as another etymotic lover imho your review is inaccurate and misleading. This product is not the holy grail, but it does not deserve your acrimony.
In reply to an earlier post on 3 Aug 2012 09:44:53 BDT
And there, amidst the personals, we have the kernel of truth. I listen to "rock" on an ipod. These earphones are just plain BAD at that. (And yes, I have sampled at the highest rate and yes i do get a perfect fit as i use and have used similar for decades...) xoxo
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John's Arm
John, the world's only city morgue night watchman with a superhero for a right arm!
It's like a party in your mouth!
Answer strange trivia questions to survive the matches!
Looks good, A team of famous newgrounds animators teaming up seems like a good idea hopefully the animation isnt too confusing with all of the different styles going on.
Try to get some good story structure because I can tell by the teaser and description its going to be pretty random series.
at the beginning when he started to breathe heavily i thought he was going to say "duuuuuuuuude
one word...EPIC! i cant wait to see this! this looks amazing. keep it up.
The loading bar is fake right click press play INSTA PLAY BUTTEN YAYZ
So I am predicting that your fella's [geek] just fantasizing all this in the end? ;)


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Marketing Officer – Communications: Social Business Wales. Location – Caerphilly
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WIP Standard
This document provides the rationale used by the Navigation Function Accessibility Subcommittee (the Subcommittee) for the development and content of a SAE J2364 Recommended Practice: Navigation and Route Guidance Function Accessibility While Driving. It provides both the reasoning for the overall recommended practice as well as each of its elements.
Technical Paper
Abstract The headliner system in a vehicle is an important element in vehicle noise control. In order to predict the performance of the headliner, it is necessary to develop an understanding of the substrate performance, the effect of air gaps, and the contribution from any acoustic pads in the system. Current Statistical Energy Analysis (SEA) models for predicting absorption performance of acoustic absorbers are based on material Biot properties. However, the resources for material Biot property testing are limited and cost is high. In this paper, modeling parameters for the headliner substrate are identified from a set of standard absorption measurements on substrates, using curve fitting and optimization techniques. The parameters are then used together with thickness/design information in a SEA model to predict the vehicle headliner system absorption performance.
Technical Paper
Abstract Sound absorption materials can be key elements for mass-efficient vehicle noise control. They are utilized at multiple locations in the interior and one of the most important areas is the roof. At this location, the acoustic treatment typically comprises a headliner and an air gap up to the body sheet metal. The acoustic performance requirement for such a vehicle subsystem is normally a sound absorption curve. Based on headliner geometry and construction, the sound absorption curve shape can be adjusted to increase absorption in certain frequency ranges. In this paper an overall acoustic metric is developed to relate design parameters to an absorption curve shape which results in improved in-vehicle performance. This metric is based on sound absorption coefficient and articulation index. Johnson-Champoux-Allard equivalent fluid model and diffuse field equations are used. The results are validated using impedance tube measurements.
Technical Paper
Abstract Five parameters are often used in acoustic modeling of porous absorption material, which are air flow resistivity σ, porosity φ, tortuosity α∞, viscous and thermal characteristic lengths Λ and Λ′. These parameters are not easy to be directly tested, especially the latter three parameters. One software capable of identifying inversely these parameters from impedance tube test results becomes increasingly popular. However, its detail stability analysis is rarely reported till now. This paper studies its stability on those porous fiber materials generally applied in vehicle interior trim, such as PET fiber, shoddy, PP/PET mixed fiber. Some conclusions are obtained. (1) The identification of α∞, Λ and Λ′ is always stable when σ and φ are assumed in advance.
Technical Paper
Abstract Passengers' thermal comfort inside a car cabin is mainly provided by the Heating, Ventilation and Air Conditioning (HVAC) module. Air provided by HVAC is blown via a blower, passing through different components: flaps, thermal exchangers, ducts… and then distributed to car cabin areas. Interaction between airflow and HVAC components generates noises that emerge in car cabin. Due to this fact, noise is naturally created and its level is linked to flow rate. Valeo is aiming, though CEVAS project, to develop a prediction tool which will provide HVAC spectrum and sound quality data. This tool will be based, in particular, on aeroacoustic measurements using 2N-ports model and Particle Image Velocimetry methods to provide characteristics of HVAC components.
Technical Paper
Abstract The need in the automotive industry to understand the physical behavior of trims used in a vehicle is high. The PEM (poro-elastic method) was developed to permit an explicit representation of the trims in the FEM full vehicle models and to give tools to diagnose the effect of the trims and test design changes (porous material property, geometry, etc.,). During the last decade, the evolution of software and hardware has allowed the creation of models with highly detailed trim description (porous material using Biot parameters, plastic trims, etc.,). These models can provide good correlation up to 400Hz compared to measurements in contrast to classical NSM (Non Structural Mass) methodology which shows limitations.
Technical Paper
Abstract Several of the exterior noise sources existing around a vehicle can cause airborne noise issues at relatively low frequencies. SEA, traditionally used for airborne sound issues is not suitable for the frequency range of interest. Finite Element analysis has been used. Handling of the non-reflecting condition on the outer boundary of the exterior cavity is an issue. Recently, advances have been made in several commercially available codes, which made the analysis practical. Including the poro-elastic material model for foam-based carpets is also becoming practically possible. The purpose of the current study is to investigate the practical applications of those new developments against test data, and to estimate the feasibility of using these procedures in the vehicle development projects. Measurements were carried out in a new semi-anechoic chamber at Volvo Cars.
Technical Paper
Abstract Modern automotive seats require improvements in their design, safety, comfort including sitting and riding comfort. Among those, seat comfort is known to be difficult to evaluate because the comfort is a human feeling. As an approach to evaluate the human comfort in an objective manner, an objective measure is proposed for seat riding comfort evaluation under low frequency vibratory conditions which represents typical roll and pitch motions of driving motor vehicles. The related feeling due to this low frequency vehicle motion is termed 'hold feeling' because the seated body may tend to deviate from the defined seating position under such vehicle motion input. Dynamic pressure measurements have been conducted in the frequency range up to 1.0 Hz to monitor the interface pressure change behavior of the seat-subject body.
Technical Paper
Abstract This paper presents the methodology of predicting vehicle level automotive air-handling system air-rush noise sound quality (SQ) using the sub-system level measurement. Measurement setup in both vehicle level and sub-system levels are described. To assess the air-rush noise SQ, both 1/3 octave band sound pressure level (SPL) and overall Zwicker's loudness are used. The "Sound Quality Correlation Functions (SQCF)" between sub-system level and vehicle level are developed for the specified climate control modes and vehicle segment defined by J.D. Power & Associates, while the Zwicker's loudness is calculated using the un-weighted predicted 1/3 octave band SPL. The predicting models are demonstrated in very good agreement with the measured data. The methodology is applied to the development of sub-system SQ requirement for upfront delivery of the optimum design to meet global customer satisfaction
Journal Article
Abstract Refrigerant flow-induced gurgling noise is perceived in automotive refrigerant systems. In this study, the condition of the gurgling generation is investigated at the vehicle level and the fundamental root cause is identified as the two-phase refrigerant flow entering the TXV for system equipped with variable displacement compressors. By conducting literature reviews, the acoustic characteristics of the flow patterns and the parameters affecting the flow regimes in horizontal and vertical tubes are summarized. Then the gurgling mechanism is explained as the intermittent flow is developed at the evaporator inlet. In the end, the improved and feasible design for avoiding the intermittent flow (slug, plug or churn flow) or minimizing its formation is proposed and verified in refrigerant subsystem (RSS) level. Finally, the guidelines for the attenuation and suppression of the gurgle are provided.
Flow-Induced Whistle in the Joint of Thermal Expansion Valve and Suction Tube in Automotive Refrigerant System
Journal Article
Abstract In the thermal expansion valve (TXV) refrigerant system, transient high-pitched whistle around 6.18 kHz is often perceived following air-conditioning (A/C) compressor engagements when driving at higher vehicle speed or during vehicle acceleration, especially when system equipped with the high-efficiency compressor or variable displacement compressor. The objectives of this paper are to conduct the noise source identification, investigate the key factors affecting the whistle excitation, and understand the mechanism of the whistle generation. The mechanism is hypothesized that the whistle is generated from the flow/acoustic excitation of the turbulent flow past the shallow cavity, reinforced by the acoustic/structural coupling between the tube structural and the transverse acoustic modes, and then transmitted to evaporator. To verify the mechanism, the transverse acoustic mode frequency is calculated and it is coincided to the one from measurement.
Journal Article
For the automotive industry, acoustic comfort is of increasing importance. The market and customer expectation make the HVAC system noise quality a question to be addressed as early as possible in the vehicle development process. On one hand, the so-called traditional sources of annoyance such as engine, road-tires contact, exhaust systems and wind-noise have been significantly reduced for most traditional combustion engine vehicles. On the other hand, considered in the past as secondary noise sources, HVAC systems become the main sources for hybrid and electric and Stop-start vehicles. Previous studies have demonstrated the ability of a CFD/CAA approach based on the Lattice Boltzmann Method (LBM) to predict HVAC system noise including real and complex ducts, registers, mixing unit and blower geometries.
WIP Standard
This document provides an overview on how and why EGR coolers are utilized, defines commonly used nomenclature, discusses design issues and trade-offs, and identifies common failure modes. The reintroduction of exhaust gas into the combustion chamber is just one component of the emission control strategy for internal combustion (IC) engines, both diesel and gasoline, and is useful in reducing exhaust port emission of Nitrogen Oxides (NOx). Other means of reducing NOx exhaust port emissions are briefly mentioned, but beyond the scope of this document.
Hand gesture transfer of information from the center console screen to the head-up display or gauge cluster display is a featured capability shown in a demonstration vehicle.
Touch screens have become a common interface between drivers and their vehicle. But touch screens can also be distracting. In this episode of SAE Eye on Engineering, Senior Editor Lindsay Brooke looks at Continental Automotive's new haptic feedback display.
The company has put its first complete touch display with haptic feedback into demonstrator vehicles as a prelude to production. The unit is a touch-sensitive 8-in flat screen with an integrated haptic actuator system.
Motorists may soon be able to point the headlamps of their cars with just their eyes to see better at night.
This document specifies the minimum recommendations for Blind Spot Monitoring System (BSMS) operational characteristics and elements of the user interface. A visual BSMS indicator is recommended. BSMS detects and conveys to the driver via a visual indicator the presence of a target (e.g., a vehicle), adjacent to the subject vehicle in the "traditional" Adjacent Blind Spot Zone (ABSZ). The BSMS is not intended to replace the need for interior and exterior rear-view mirrors or to reduce mirror size. BSMS is only intended as a supplement to these mirrors and will not take any automatic vehicle control action to prevent possible collisions. While the BSMS will assist drivers in detecting the presence of vehicles in their ABSZ, the absence of a visual indicator will not guarantee that the driver can safely make a lane change maneuver (e.g., vehicles may be approaching rapidly outside the ABSZ area).
The scope of this document is a technology-neutral approach to speech input and audible output system guidelines applicable for OEM and aftermarket systems in light vehicles. These may be stand-alone interfaces or the speech aspects of multi-modal interfaces. This document does not apply to speech input and audible output systems used to interact with automation or automated driving systems in vehicles that are equipped with such systems while they are in use (ref. J3016:JAN2014).
Determine the required minimum oxygen concentration to be breathed prior to, during, and after a loss of cabin pressurization, and determine recommended means necessary to provide the required oxygen concentrations.
This SAE Aerospace Recommended Practice (ARP) defines recommended analysis and test procedures for qualification of pneumatically, electrically, manually, and hydraulically actuated air valves. They may be further defined as valves that function in response to externally applied forces or in response to variations in upstream and/or downstream duct air conditions in order to maintain a calibrated duct air condition (e.g., air flow, air pressure, air temperature, air pressure ratio, or air shutoff). Qualification testing performed on the airplane to verify compatibility of the valve function and stability as part of a complete system is outside the scope of this document. Refer to ARP1270 for design and certification requirements for cabin pressurization control system components. As this document is only a guide, it does not supersede or relieve any requirements contained in detailed Customer specifications.
A second coolant loop in a Fiat Grande Punto prototype provides liquid cooling of the A/C condenser and turbo intercooler, with potential for including air coolers for engine and transmission oil, power steering fluid and other heat exchangers. Engineers measured a 5% improvement in fuel economy during A/C-on operation during NEDC testing.
WIP Standard
This SAE Recommended Practice applies to both Original Equipment Manufacturer (OEM) and aftermarket route-guidance and navigation system functions for passenger vehicles. This recommended practice provides a method for calculating the time required to complete navigation system-related tasks. These estimates may be used as an aid to assess the safety and usability of alternative navigation and route guidance system interfaces to assist in their design. This document does not consider voice-activated controls, voice output from the navigation system, communication between the driver and others, or passenger operation.
This document defines the method for voltage identification by the use of color-coded insulators at the base of the lamps. Table 1 shows the design volts and corresponding insulator colors. The part numbers shown are for example purposes only, as an option. Insulator colors are to be easily distinguishable as green, yellow, red, and white. Additional colors may be added by a revision process as required.
R-1234yf and R744 Design Criteria and Certification for OEM Mobile Air Conditioning Evaporator and Service Replacements
The intent of this standard is to establish a framework to assure that all evaporators for R-744, R-1234yf, and R-445A mobile air conditioning (MAC) systems meet appropriate testing and labeling requirements. SAE J639 requires vehicle manufacturers to perform assessments to minimize reasonable risks in production MAC systems. The evaporator (as designed and manufactured) shall be part of that risk assessment and it is the responsibility of the vehicle manufacturer to assure all relevant aspects of the evaporator are included. It is the responsibility of all vehicle or evaporator manufacturers to comply with the standards of this document at a minimum. (Substitution of specific test procedures by vehicle manufactures that correlate well to field return data is acceptable.) As appropriate, this standard can be used as a guide to support risk assessments.
The scope of this SAE Standard is to provide methods to determine display optical performance in all typical automotive ambient light illumination - with focus on High Ambient Contrast Ratio, which is critical for display legibility in a sunshine environment. It covers indoor measurements and simulated outdoor lighting. It is not the scope of this document to set threshold values for automotive compliance. However some recommended values are presented for reference.
WIP Standard
Presents the seating accommodation model used to determine seat track length for accommodation in design.
Plastic Material or Materials for Use in Optical Parts Such as Lenses and Reflex Reflectors of Motor Vehicle Lighting Devices
WIP Standard
This SAE Recommended Practice provides test methods and requirements to evaluate the suitability of plastic materials intended for optical applications in motor vehicles. The tests are intended to determine physical and optical characteristics of the material only. Performance expectations of finished assemblies, including plastic components, are to be based on tests for lighting devices, as specified in SAE Standards and Recommended Practices for motor vehicle lighting equipment. Field experience has shown that plastic materials meeting the requirements of this document and molded in accordance with good molding practices will produce durable lighting devices.
Numerical and Experimental Investigation of Thermal Conditions Inside the Engine Compartment of Snowmobiles
Journal Article
Abstract Nowadays, investigating underhood airflow by using numerical simulation is a standard task in the development process of passenger cars and commercial vehicles. Numerous publications exist which deal with simulating the airflow through the engine compartment of road vehicles. However, hardly anything can be found which deals with off-road vehicles and nothing exists which focuses on snowmobiles. In the presented paper the airflow and the thermal conditions inside the engine compartment of a snowmobile are investigated by the usage of computational fluid dynamics (CFD) as well as experimental methods. Field tests at arctic conditions have been conducted on a serial snowmobile to measure temperatures inside the compartment and to gain realistic boundary conditions for the numerical simulation. Thermocouples (type K) were attached under the hood to measure exhaust, air, coolant and surface temperatures of several components at previously defined load cases.
Unmanned Aerial Systems Deploying Next-Generation UAS Platforms with 3U VPX Unmanned Ground Vehicles UGVs - On the Cutting Edge of Thermal Management Unmanned Surface/Underwater Vehicles Controlling the Seas - Introducing a New Concept in Autonomous Surface/Underwater Vehicles Robotics Connectivity in Robotic Systems
Commercial Vehicle
Technical Paper / Journal Article


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Isabella Cruise and Katie Holmes - Isabella Cruise, Katie Holmes and Suri Cruise Monday 21st June 2010 at Manhattan Hotel New York City, USA
Ricki and the Flash is a music comedy drama about the high price of a musician's pursuit of fame.
The new doc comes courtesy of '20 Feet From Stardom' filmmaker Morgan Neville.
Gaz Coombes has reworked the title track from his latest solo album 'Matador' and is planned to be released as a limited edition EP on numbered and...
Pine will star opposite Gal Gadot in the upcoming Warner Bros. comic book movie.
The model turned actress was promoting her new movie 'Paper Towns' on the early morning talk show.
Sweet Baboo (aka Stephen Black) is set to release his fifth studio album The Boombox Ballads on August 14th through Moshi Moshi.


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Shortcake with Peaches and Cream
In the mood for a heavenly summer treat? Combine moist shortcake, sweet peaches, and soft whipped cream.
Total Time:
Level: Easy
Yield: 6 servings
Serves: 6
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- 2 c. biscuit mix
- 0.33 c. sugar
- 0.50 vanilla bean seeds
- 0.33 c. heavy cream
- 0.33 c. cold water
Peaches and Cream
- 4 medium peaches
- 2 tbsp. sugar
- 0.50 vanilla bean seeds
- 0.50 c. heavy cream
- Prepare the shortcake: Preheat oven to 350°F. Mix biscuit mix with sugar and seeds from half of a vanilla bean in a medium bowl. Stir in heavy cream and water. Transfer batter to lightly oiled 8-inch cake pan and bake until a skewer inserted in center of cake comes out clean, about 25 minutes. Set pan on a wire rack and cool for 15 minutes. Release cake from pan and cool completely.
- Meanwhile, peel, pit, and slice 4 medium peaches. Toss with 2 tablespoons sugar and seeds from remaining half of vanilla bean in medium bowl; let sit 15 minutes, to allow peach juices to release. For whipped cream, beat heavy cream to soft peaks. Chill both peaches and cream.
- Cut cake into wedges. Split each piece, spoon peaches onto bottom halves, cover with top halves, and drizzle with juice. Serve with a dollop of whipped cream.
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N K Sinha, a 1980 batch IAS officer, was yesterday appointed Secretary, Culture Ministry. He is presently serving in his cadre state, Bihar. NEW DELHI: K D Tripathi, who was yesterday appointed as the new Petroleum Secretary, would continue to hold the ...Economic Times, 2 months ago K D Tripathi to hold addl charge of Secretary, DPE Business Standard, 2 months ago
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Nino Alvarez
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This season you may as well put all of your ordinary staple denims in storage because pops of print is having a MAJOR moment! Jenna Dewan Tatum was recently spotted wearing hers during travel.
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1-16 of 308,368 results for "App Store"
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The AppStoreApr 22, 2014by FOM Developer
Product Features
- All Ages
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ProSelect® Control Bowl
Roll over image to zoom in
- Pink Blossom -- ($14.95) 8.5 " diameter x 1.5" H (21.6 x 3.8 cm) and holds 1 1/4 cups
- Blue Mist -- ($20.95) -- 11.5" diameter x 2.5" H (29.2 x 6.4 cm) and holds 4 cups
- Jet Black -- ($26.95) -- 14.5" diameter x 3" H (36.8 x 7.6 cm) and holds 7 cups
- 100% Melamine
- Four convenient notches around the bowl's rim allow for easy pick up off the floor
- Non-skid rubber rim
- Dishwasher-safe
- Imported
This item ships from a third party and may be excluded from certain promotions. Please see the Current Promotions page for details.
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August 13, 2013 - I have a hound dog who vacuums up his food before I barely get it put down. This bowls works GREAT! It was exactly what I was looking for and makes him slow down and eat at a normal healthy pace. Thank you so much for making these. Plus, it is made of a very heavy plastic that seems unbreakable, and it stays very clean, I barely have to rinse it. I highly recommend these bowls if you have a fast eater.
January 8, 2013 - Heavy, Durable & undoubtedly awesome for my male black lab who inhales his food. The Blue Mist size was ample enough for us & I am glad I did not get the black, which would have been way too big.
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Herb Pharm, Witch Hazel, 1 fl oz (29.6 ml)
Items 1-3 of 3 total
Herb Witch Hazel
2 people found the following review helpful
Posted by Reviewer1848228 on Sep 06, 2011
This is great for pets ! I put a little on a cotton ball and clean their ears. My daughters uses it for bug bites it stops the itch !
Was this review helpful to you?
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Note: iHerb does not imply any medical claims from this review. Disclaimer.
Debbie in Arizona
1 person found the following review helpful
Posted by Reviewer2138857 on Sep 13, 2008
Like this product. My son that doesn't use the Source Naturals Skin Eternal cream, gets eaten by mosquitos and uses this product to stop the itching.
Great product and great price
Posted by Reviewer1789145 on Jul 09, 2013
I use this in a herbal formulation and get great results


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Spring Hill News
Local news for Spring Hill, TN continually updated from thousands of sources on the web.
Correction for HarMoniX story
22 hrs ago | Columbia Daily Herald | Comment?
Local governments prepare for same-sex marriage benefits
Wednesday Jul 29 | Columbia Daily Herald | Comment?
Success of TN Promise hinges on student retention
Friday Jul 24 | WBIR-TV Knoxville | Comment?
LIFT and LEAP launch science teacher program
Thursday Jul 23 | Lebanon Democrat | Comment?
Flags stand in a make-shift memorial as people gather at the scene of ...
Tuesday Jul 21 | ABC 27 | Comment?
Spring Hill approves site for Bojangles restaurant
Sunday Jul 19 | Columbia Daily Herald | Comment?
What 41 Female Celebs REALLY Weigh
Same Sex Marriage: It's Officially Legal
Legislation 835
Loosing Innocent Lives In An Airstrike: Do the Pros Out...
news 620
Homeowner Accused of Hiding Sinkhole from Homebuyer
Friday Jul 17 | ABC News | Comment?
Budget committee suggests 12-cent county tax hike
Wednesday Jul 15 | Columbia Daily Herald | Comment?
Study shows large increase in Tennesseea s vehicle exports
Sunday Jul 12 | WATE-TV Knoxville | Comment?
Spring Hill student to compete in national rodeo finals
Thursday Jul 9 | Columbia Daily Herald | Comment?
Goodwill to host job fair today
Monday Jul 6 | Columbia Daily Herald | Comment?
Updated: Sat Aug 01, 2015 10:34 pm
Copyright © 2015 Topix LLC


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Neil Young & Crazy Horse Perform at Hurricane Sandy Benefit Concert Tonight
Neil Young & Crazy Horse have announced that they will perform a special benefit concert tonight, December 6th, 2012, at Borgata Hotel Casino & Spa in Atlantic City, NJ, with proceeds going to aid victims of Superstorm Sandy. Devastated by the damage and displacement caused by hurricane, Young urged: "Come on down here and join in the relief effort."
Proceeds will go to the AMERICAN RED CROSS HURRICANE SANDY relief effort. For more info go to: redcross.org/hurricane-sandy
Tickets for the event, billed as "A Special Evening With Neil Young & Crazy Horse," go on sale Friday, November 30 at 10am at TheBorgata.com or by-phone at 866-900-4TIX (4849) and will be priced at $75 and $150. All seating is general admission. Everest will open the show. Young will be available for a select number of interviews regarding the Hurricane relief.
Crazy Horse, which is Young, Billy Talbot, Ralph Molina, and Poncho Sampredo, has been touring North America this in support of its latest album Psychedelic Pill.
About Author
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Thu, 10/01/2013 - 16:22
Sidley Austin has appointed Michael J O'Brien as a partner in its New York office.
O'Brien will be a member of the firm's M&A and private equity group.
O'Brien focuses his practice on mergers and acquisitions, private equity and joint venture transactions. For over 30 years, O'Brien has provided strategic counsel to clients including private equity firms and financial institutions on both public and private investment transactions. He has also represented public and private companies in domestic and international joint ventures, financing transactions and corporate and securities matters. His private equity experience ranges from advising clients on start-up capital investments strategies to large leveraged buyouts.
"We are excited to welcome Mike to our talented team of lawyers here in New York," says Michael J Schmidtberger, managing partner of Sidley's New York office. "His extensive experience in all forms of M&A and private equity transactions will allow us immediately to further expand our offerings to clients engaging in these types of opportunities."
"In my estimation, there are few firms that have the breadth of resources Sidley makes available to its M&A and private equity clients," says O'Brien. "I am pleased to have the opportunity to add further value to the services provided by its worldwide team."
See interviews and presentation at the Wealth Adviser 2015 awards ceremony, held at Sketch, Mayfair on the 15th May .... »
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Tue, 28 Jul 2015 00:00:00 GMTExecutive Assistant
Tue, 28 Jul 2015 00:00:00 GMTTrade Support Engineer - Leading Broker-Dealer
Tue, 28 Jul 2015 00:00:00 GMT