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103 Matching Results
Intel Resources for Game DevelopersIntel® HD Graphics and Intel® IrisTM and IrisTM Pro Graphics parts are some of the most commonly used graphics solutions in PCs worldwide. By following the advice on these pages and using the tools we provide, you'll ensure that your game is able to be enjoyed by millions of gamers. We want you to be successful
How Direct3D is Driving Games from Casual to AAA by Chas Boyd (Microsoft)
Watch this talk from Microsoft's Chas Boyd on how DirectX 12 enables casual and indie games to take advantage of the latest and best graphics features to deliver improved performance, better batter
Windows* 8 Tutorial: Writing a Multithreaded Application for the Windows Store* using Intel® Threading Building Blocks.
It is known that the Windows Store apps API is missing some commonly used thread functions, such as function CreateThread() and those that work with TLS keys.
Power ExplorerToday any review of a new processor whether it's used in a desktop computer, a laptop, a tablet or a phone will contain lots of information about how efficient it is and the new technologies that have been used to achieve this performance. Operating system developers spend large amounts of time optimizing improve efficiency and extend battery life, but what can be done by someone who is designing...
High-Performance Games: Addressing Performance Bottlenecks with DirectX*, GPUs, and CPUsThe last decade has seen tremendous advances in the field of computer graphics. This article presents an overview of common graphics pipeline bottlenecks and explains how recent advances in DirectX and graphics hardware are helping to overcome them.
Removing CPU-GPU sync stalls in Galactic Civilizations* 3Galactic Civilizations* 3 is a turn-based 4X strategy game recently released by Stardock Entertainment. This article describes how Intel® INDE Graphics Performance Analyzer's (GPA) Platform Analyzer was used to improve the game's performance by finding and removing several CPU-GPU sync stalls that had caused a loss of parallelism between the CPU and GPU.
Deferred Rendering for Current and Future Rendering PipelinesThis sample demonstrates a number of deferred rendering techniques including conventional deferred shading, deferred lighting and tile-based deferred shading. Tile-based deferred shading is implemented in DirectX 11 Compute Shader and achieves high performance even with many lights by amortizing the light culling overhead over screen tiles as well as grouping lights to avoid wasting memory...
NEW Intel® Iris™, Iris™ Pro, and HD Graphics Driver update posted for Haswell and Broadwell version 188.8.131.5222
Please see the release notes and excerpt below for details.
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For more complete information about compiler optimizations, see our Optimization Notice.


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Monday, 28 Feb 2011 03:53 PM
House Republicans' $61 billion budget-cutting plan would cost 700,000 jobs, according to a report likely to inflame the debate over the U.S. government deficit.
The measure would reduce real economic growth this year by 0.5 percentage points and by 0.2 percentage points next year, resulting in 700,000 fewer jobs by the end of 2012, said Mark Zandi, chief economist for Moody's Analytics.
He said budget-cutters should wait until the U.S. economy is stronger, saying Republicans "would be taking an unnecessary chance with the recovery."
"Significant government spending restraint is vital, but given the economy's halting recovery it would be counterproductive for that restraint to begin until the U.S. is creating enough jobs to lower the unemployment rate," Zandi said.
The House approved its plan Feb. 19. Democrats who control the Senate have said they wouldn't accept the reductions.
A spokesman for House Speaker John Boehner, an Ohio Republican, dismissed Zandi's report.
"The fact that a relentless cheerleader for the failed 'stimulus' — which the Democrats who run Washington claimed would keep unemployment below 8 percent — refuses to understand that ending the spending binge will help the private sector create jobs is sad, but not surprising," said Michael Steel.
The U.S. unemployment rate was 9 percent in January.
Last week, Goldman Sachs said the House budget plan would shave between 1.5 and 2 percentage points off economic growth during the second and third quarters of this year.
Zandi said the proposed spending cuts would come at a particularly inopportune time because the economy is under new pressure from rising oil prices, pushed upward by the unrest in the Middle East. He said the plan would also undo some of the economic boost provided by the Federal Reserve and the $858 billion tax-cut package approved in December by Congress.
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Nutricology, ProGreens, with Advanced Probiotic Formula, 9.27 oz (265 g)
Items 26-30 of 49 total
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Great way to get your greens!
Posted by Reviewer3108583 on Jul 03, 2008
Current nutritional research shows that we should be having at least 5 cups of veggies a day. This is my back up for the days that I don't get enough and my health care provider recommends it as a meal substitute for people who are trying to lose weight as well. It is the best tasting green supplement I have tried and also the most non-allergenic for those of you (like me) with food allergies.
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Note: iHerb does not imply any medical claims from this review. Disclaimer.
Wonderful, broad-spectrum supplement
Posted by Reviewer1352960 on Jan 25, 2007
I've been using Progreens for awhile now (mixed into a small amount of apple juice), and feel that it is a simple way to make sure that I get all the "extras" I need, plus probiotics.
Posted by Reviewer2726790 on Nov 08, 2007
Posted by Reviewer1468278 on Nov 22, 2007
Great stuff, and doctor recommended for health and energy -- please keep it in stock permanently!
Get your greens!
Posted by alison-lane on Dec 20, 2007
Great product. I have loads more energy - some would say too much!


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Richardson played for the Heat summer leauge team in Orlando and Las Vegas. He played in 10 games (six starts), averaging 11.8 points, 2.8 rebounds, 1.7 steals and 1.6 assists in 26.1 minutes per game.
Richardson was selected in the second round (40th overall) of the 2015 NBA Draft. He played four seasons at Tennessee (136 games), averaging 9.2 points, 3.2 rebounds, 1.8 assists, 1.1 steals and 28.2 minutes per game.Analysis:
Anderson was selected 21st overall out of Virginia. He averaged 17.5 points 4.2 rebounds, 1.5 assists and 1.2 steals in Summer League.Analysis:
Hamilton was signed to a 10-day contract in February and later signed for the rest of the season. He averaged 2.7 points, and 1.1 rebounds this year.Analysis:
Douglas averaged 4.3 points and 2.0 assists per game in 12 games for New Orleans last season.Analysis:
Mudiay was the seventh-overall pick in the 2015 NBA Draft.Analysis:
Vujacic played in two games for the Clippers last season. In eight seasons, Vujacic has a career average of 5.6 points per game.Analysis:
Ledo split last season between Dallas and the Knicks, averaging 5.3 points and 2.1 rebounds.Analysis:
The team was criticized for taking Porzingis with the No. 4 overall selection in the 2015 draft. He is considered a project.Analysis:
Miller averaged 4.4 points and 3.5 assists in 81 games for the Wizards and Kings last season.Analysis:


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Andras Advertising
448 Julia St. Loft 201
New Orleans, LA 70130
Phone: 504-722-8960
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Lead411 offers quality contact information on a variety of companies including that of 504ward's CEO . The company profile also contains facebook info, linkedin accounts, phone numbers, cfo contacts, and 504ward email addresses with the domain format of @504ward.com. 504ward, is in the Other field. If you sign up for our free trial you will see our email@example.com addresses.
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How to convert your mountain bike to a 1BY drivetrain Between SRAM's groupsets, direct mount cranks, and extended range cogs, there are plenty of options to convert your bike to a 1BY mountain machine In 2013, SRAM shook up the MTB component scene when XX1 hit the market. Rather than the latest-and-greatest drivetrain getting more […]Read More
MTB-Mag's First Look at the Range C 7.1
Ian Collins from MTB-MAG.com just built up the Range C 7.1 he'll be testing. See more of Ian's gorgeous First Look/Bike Porn images here. Stay tuned for the full review!Read More
Sea Otters and Paris Ancasters: An Evan McNeely Blog
Sea Otters and Paris Ancasters By Evan McNeely I had a post titled "The Classic Sea Otter Classic" sitting in my drafts for all of last week. I never got around to finishing it because I was busy littering the exam halls with broken mechanical pencil lead. It is hard to find a point in finishing it […]Read More
Sea Otter Classic – 25th Anniversary Edition
The Sea Otter Classic is always a great time, and the 25th edition was no exception. Sunshine, a Bicycling Magazine Editor's Choice award, and great performances from all the Norco athletes present made for an eventful four days! Here are a couple photos of the highlights from this year's event. Great scenery on the drive […]Read More
Haley Smith's Blog: PanAm Champs – Cota, Colombia
PanAm Champs – Cota, Colombia Well, things sure are wild south of the equator. This past week was my first trip to the Southern Hemisphere, and it was quite the experience. After a brief altitude camp with the National Team in Big Bear, California, we packed up and headed out to Bogota, Colombia. Words can't […]Read More
Steak Sauce Has a New Favourite, Go-To Norco… Do You?
Steak Sauce Weighs in on His New Favourite Ride! by: Pete Stace-Smith, Norco Brand Ambassador For those of you who may not know me, please allow me to introduce myself: my name is Pete SS, or Steak Sauce – as many of my friends and co-workers call me. I've had the privilege of working for […]Read More
Norco Factory Racing: Meet the Team
Introducing: Sam Blenkinsop "I started DH in my home town and I had friends that were racing and they told me to come to a race and from then on loved it. The thing I most love about DH would have to be the speed, every year it seems to get faster and faster. One […]Read More
The Aurum Carbon Killer B Makes Its Debut in the Dusty Hills of Idyllwild, California
Exclusive Media Launch Event Introduces the New Aurum Carbon Downhill Race Bike Last month, we invited a select group of mountain bike media from around the world to experience the Aurum Carbon Killer B at an exclusive pre-launch event in Idyllwild, California. Our goal was to give attendees some spin-free insight into our goals for […]Read More
Norco Factory Team Season Opener – US Cup: Bonelli Park
I'M STILL PARCHED. – Haley Hunter Smith Saturday, March 14, 2015: XC Race: 12th (Full results) Sunday, March 15, 2015: Short Track: 8th (Full results) The 2015 race season is officially underway. Which is pretty bizarre, considering it's only March 16th. Us Canadians are used to a much later start to the calendar (seeing as […]Read More
Thanks Norco – It Has Been a Great Ride!
Looking Back on Seven Years of Innovation by Dustan Sept – Former Marketing Department Supervisor In May of 2008, Norco Bicycles was a much different beast than it is today. I started working with the Norco marketing team nearly seven years ago, and on that first day the bikes, the people and the industry seemed […]Read More


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- Forum: Tour Talk
The word potential doesn't belong in the same sentence, much less the same conversation when talking about Spieth. He shed the potential label years ago because he was a winner since day 1. Potential was shed for "expectations" - and he's steamrolled every expectation since. Schniederjans has shown potential for sure - but to realistically accomplish the resume of Spieth, he'll likely be pushing 30 by the time that happens - if it ever does.


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Neighbor had a pack of Teddy's favorite cigarettes. (imgur.com)
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DIY Earthbound Themed Wallets [Link in comments] (m.imgur.com)
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HOW TO PLAY LUCAS 101 (youtube.com)
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We are doing a play through of Mother 3 for the first time. Come join us! (twitch.tv)
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EarthBound Super Series (self.earthbound)
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I have finished Earthbound. (self.earthbound)
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Mother 3 review blog series (squarecandies.wordpress.com)
Itoi's Letter to Iwata (youtube.com)
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MOOBER 3 (101239.deviantart.com)
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I tried drawing all the different Mother characters interacting with one another! (imgur.com)
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RIP (MOTHER 3 SPOILERS) (youtu.be)
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Just when you thought Giygas couldn't get creepier... (psychic-vr-lab.com)
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"Does he slap people on the face with his shoes?!?!" (self.earthbound)
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I haven't played a single mother game but (self.earthbound)
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[Mother 3 spoilers] I cried... (self.earthbound)
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What would be in a "skip sandwich" in real life? (self.earthbound)
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"You must be so exhausted..." - custom amiibo collaboration with SaiyanSerenityV. (imgur.com)
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Why is there a mini clayman in Bateau's house (Ch. 1)? (imgur.com)
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Ness' Nightmare (self.earthbound)
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Earthbound Reference on Teen Titans GO! (listen to the music at (1:41) (youtu.be)
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1-16 of 333 results for Books : $500-$999 :
Puffin Classics Grimms' Fairy TalesMay 29 2012by Jacob Grimm and Wilhelm Grimm
Clara the Cookie Fairy StorybookJan 28 2014by Make Believe Ideas
The Wonder Smith and His Son: Tales from the World's Golden ChildhoodJul 2 2013by Ella Young and Ken McIntosh
The Stars in the SkySep 22 2009by Leigh OlsenExcerpt
Front Matter : ... ReadersTM (fiction stories that ... puzzling tales where children ...See a random page in this book.
Weighing the ElephantSep 1 1998by Ting-xing Ye and Suzane Langlois
Beyond the Tower (Tangled)Sep 14 2010by Heather Knowles and Jean-Paul Orpinas
The Big Milly-Molly-Mandy StorybookSep 2000by Joyce Lankester BrisleyExcerpt
Front Face : ... delight. These timeless tales will touch a chord with all ...See a random page in this book.
The Key of the KingdomOct 2004by Elizabeth Gmeyner and Joyce Russell
Lift The Flap Fairy Tales Little Red Riding HoodAug 6 2010by Nick Sharratt


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Ready 321 Photography
$79 for an Outdoor On-Location Holiday Themed Photo Shoot from Ready 321 Photography ($200 Value)
The Fine Print
- Expires 90 days after purchase.
- Limit 1 per person, may buy 1 additional as gift. Limit 1 per visit. Appointment required. 24-hr cancellation notice required. Valid only within 20 miles of 90630. Must sign Ready 321 contract prior to shoot.
- See the rules that apply to all deals.


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OCZ Vertex 460 240GB SSD Review - Packaging and Accessories
Packaging and Accessories
OCZ put together an attractive package for the Vertex 460. I'm surprised this is the first time OCZ used the black and blue combination, but I couldn't find another 2.5" drive with this combination before.
Most of the time we just glance over the product packaging, but this one is inspiring when you spend a few minutes with it. '... the Vertex 460 Series is built to provide years of hard drive - humiliating performance. Ditch that spinning HDD for some storage peace of mind." It's not Shakespeare, but it's a bit more entertaining than what we're accustomed to reading on the back of a box.
Inside we found what we started calling the Vertex Standard a few years ago. The drive is packaged well, includes a key for Acronis True Image, paper warranty info, a sticker and desktop adapter bracket (not shown).
Here we see the hardware accessories included.
PRICING: You can find products similar to this one for sale below.
United States: Find other tech and computer products like this over at Amazon's website.
United Kingdom: Find other tech and computer products like this over at Amazon UK's website.
Australia: Find other tech and computer products like this over at PLE Computer's website.
Canada: Find other tech and computer products like this over at Amazon Canada's website.
- Page 1 [Introduction]
- Page 2 [Specifications, Pricing and Availability]
- Page 3 [Packaging and Accessories]
- Page 4 [OCZ Vertex 460 240GB SSD]
- Page 5 [Benchmarks - Test System Setup and ATTO Baseline Performance]
- Page 6 [Benchmarks - Sequential Performance]
- Page 7 [Benchmarks - AIDA64 Random Access Time]
- Page 8 [Benchmarks - Anvil Storage Utilities]
- Page 9 [Benchmarks - CrystalDiskMark]
- Page 10 [Benchmarks - PCMark Vantage Hard Disk Tests]
- Page 11 [Benchmarks - PCMark Vantage - Drives with Data Testing]
- Page 12 [Benchmarks - PCMark 8 Hard Disk Tests]
- Page 13 [Benchmarks - DiskBench]
- Page 14 [Final Thoughts]
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Further Reading: Read and find more Storage content at our Storage reviews, guides and articles index page.
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- Unigen Announces DDR4 Modules


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Blondes suck at math, pugs rock at climbing, and sharks rock at EVERYTHING!
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text: Vintage Style First Aid Box by Garden Trading £28$60.67€41.43$46.06 In stock This item is not available for delivery to United States. International delivery available quantity by Garden Trading Location: Oxon, GB read seller's profile see seller's complete range more items from this seller Aldsworth Outdoor Storage Box Large £195$422.56€288.58$320.81 Garden Barn Lamp £45$97.51€66.59$74.03 Grand Paris Pendant Light £65$140.85€96.19$106.93 Outdoor Swinbrook Lamp £60$130.02€88.79$98.71 Mini Bin £24$52€35.51$39.48 Square Glass Storage Jars £3.50$7.58€5.17$5.75 view all you may also like PRODUCT DETAILS CUSTOMER REVIEWS DELIVERY RETURNS ask seller a question save for later An ideal storage solution for your first aid needs. Have plasters, antiseptic and other first aid essentials to hand whenever you need them. Complete with a lift out tray and compartments to separate pills, plasters and bandages. Lightweight and fitted with easy-to-hold handles, it can be carried anywhere in the garden or home to administer relief to a patient. made from: Made from powder coated steel dimensions: H23 x W24 x D19cm product code: 217466 2 customer reviews Tue 17 Feb 2015 This box is what I wanted for storing all our medicines etc, however I do think slightly on the pricey side. Fri 05 Jul 2013 Lovely tin & looks like it will withstand the test of time so a good investment buy read about our product rating system ratings guide trusted independent customer feedbackforum excellent bad good poor This product is dispatched to you by Garden Trading. MAINLAND UK order now and receive this item on or before price Standard Delivery Wednesday 5 August £5.95$12.89€8.80$9.78 Express Next Day Friday 31 July £10.90$23.62€16.13$17.93 NON-MAINLAND UK estimated delivery price Highlands & Islands of Scotland 2-5 working daysfrom dispatch £5.95$12.89€8.80$9.78 Northern Ireland 2-5 working daysfrom dispatch £5.95$12.89€8.80$9.78 Other UK Islands 2-5 working daysfrom dispatch £14.95$32.39€22.12$24.59 INTERNATIONAL DELIVERY estimated delivery price Western Europe 2-5 working daysfrom dispatch £20.00$43.34€29.59$32.90 Rest of Europe 5-10 working daysfrom dispatch £20.00$43.34€29.59$32.90 You have 28 days, from receipt of cancellable goods, to notify the seller if you wish to cancel your order or exchange an item. Please note: goods that are personalised, bespoke or made-to-order to your specific requirements, perishable products and personal items sold with a hygiene seal (cosmetics, underwear) in instances where the seal is broken are non-refundable, unless faulty. Read more about our returns policy.Should you choose to return or exchange your order you will need to deliver the item(s) to the UK, where this seller is based. Garden Trading's return policy


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Pierre & Vacances Résidence Les Rivages du Parc - Menton, Menton
- Free WiFi in lobby
Main amenities
- 86 guestrooms
- Near the beach
- Self parking
- Garden
- Self-serve laundry
- Multilingual staff
- Porter/bellhop
What's around
- Heart of Menton
- Jean Cocteau Museum (0.6 mi / 1 km)
- Chapel of the Penitents-Blancs (0.7 mi / 1.1 km)
- Church of St Michel (0.7 mi / 1.1 km)
The location, close to beach and center and rooms has been super! There was just a little…
It's not fancy. But for the price it's okay. There was what we needed like towels and…
Enter dates to check prices
Hotel Info: 866-539-8117from $178
- Studio, 2-3
- One Bedroom Apartment, with Balcony (3, 4 people)
- Studio, 4-5
- Double Room
- Single Room
- Studio
Recommended hotels
At a glance
Key facts
Hotel size
- This hotel has 86 rooms
- This hotel is arranged over 9 floors
- Check-in time 5 PM-7 PM
- Check-out time is 10 AM
- Sunday - Friday: 9 AM - Noon
- Sunday - Friday: 3 PM - 7 PM
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- Pets allowed *
- Free WiFi in public areas
- WiFi in rooms *
- Self parking *
Nearby Three Star Menton hotels
In the hotel
- Golf lessons available nearby
- Golfing nearby
- Hiking/biking trails nearby
- Sailing nearby
- Surfing/boogie boarding nearby
- Water skiing nearby
- Windsurfing nearby
- Laundry facilities
- Elevator/lift
- Garden
In the room
- Iron/ironing board (on request)
- Blackout drapes/curtains
- Separate dining area
- Private bathroom
- Bathtub only
- Free toiletries
- Hair dryer (on request)
- Cable TV channels
- WiFi (surcharge)
- Phone
- Refrigerator
- Kitchenette
- Cookware, dishware, and utensils
- Dishwasher
- Housekeeping - once per stay
- In-room safe
Top Menton hotels
Recently reviewed hotels in Menton
- Hôtel Nice Excelsior Châteaux & Hôtels CollectionFrom
"The room was nice and the front desk staff was very helpful. However the AC didn't work, even after they "fixed" it. The cleaning staff never did a full cleaning. For example, one…"Jul 26, 2015
- Hôtel La Villa Nice Victor HugoFrom
"Our family of four happily shared one big, comfortable, clean room at La Villa. Everything was great and we would definitely stay there again."Jul 26, 2015
- Novotel Nice CentreFrom
"We enjoyed our stay at the Novotel in Nice, Centre. The breakfast in the hotel was great. Great hotel for family or for business."Jul 26, 2015
- Hotel DuranteFrom
"Difficult to find hotel by car due to one way streets. Slight odor in hallway to our room. Free parking was the big plus. Also liked the garden courtyard."Jul 25, 2015
Nearby hotels
Pierre & Vacances Résidence Les Rivages du Parc - Menton, Menton's small print
Also known as
- Pierre & Vacances RΘsidence Rivages Parc
- Pierre & Vacances RΘsidence Rivages Parc House
- Pierre & Vacances RΘsidence Rivages Parc House Menton
- Pierre & Vacances RΘsidence Rivages Parc Menton
- Pierre & Vacances Residence - Les Rivages Du Parc Hotel Menton
- Pierre & Vacances Residence Les Rivages du Parc Menton
- Pierre & Vacances Residence Les Rivages du Parc Menton Monaco
Mandatory fees
You'll be asked to pay the following charges at check in or check out:
- A tax is imposed by the city: EUR 1.50 per person, per night. This tax does not apply to children under 14 years of age.
Deposit: EUR 200 per stay
Optional extras
Late check-out can be arranged for an extra charge
Self parking costs EUR 8 per night
Safes in guestrooms can be used for EUR 3.50 per day
Cribs/Infant beds are available for EUR 40 per week
Pets are allowed for an extra charge of EUR 9 per pet, per night
WiFi is available in guestrooms for EUR 5 per night (rates may vary)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.


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- Rich Cimini, ESPN Staff Writer
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- Comment
'Tis the season for giving, and the New York Jets have given away plenty in the month of December -- a chance for the No. 1 seed in the AFC, a shot at the division title, a first-round bye, etc.
You get the picture, but the purpose here isn't to bash the Jets. After all, they're in the playoffs and, as they proved last season, all it takes is an invitation to become the life of the party.
"It's going to be hard to come back and duplicate what they did last year, but they're still a very good team and I wouldn't be surprised if that offense gets rolling," said an opposing GM, speaking on the condition of anonymity. "They're going to be a tough team to beat. You've got New England and, after that, who can't they beat?"
As they prepare for the relatively meaningless regular-season finale, with an eye on wild-card week, this is what the Jets should be focused on:
• Getting Mark Sanchez right: This means mentally and physically. The latter, of course, refers to his ailing right shoulder. Rex Ryan faces a difficult decision. He doesn't want to disrupt Sanchez's mojo -- two straight solid games against upper-echelon defenses -- but he also wants to make sure the shoulder is as close to 100 percent as possible for the playoffs.
Only Sanchez knows the true extent of the discomfort. His performance in Chicago, where the weather was cold and damp enough to stiffen the aching joint, didn't raise any red flags. As one longtime scout observed, "I saw nothing, live or on tape, that would indicate an arm issue."
Ryan should play Sanchez a few series against the Buffalo Bills. There's risk, but Sanchez's track record suggests he needs practice reps and game action to remain effective. He struggles after long layoffs. He's the Jets' meal ticket in the postseason. Funny how things change. A year ago, Sanchez was along for the ride; now he's driving the bus.
• Go Greene: Over the last two games, Shonn Greene and LaDainian Tomlinson have the same number of carries. Enough of the 50-50 stuff. It's time for the Jets to make Greene the featured back, as they did last season during the playoff run.
Tomlinson still is valuable as a receiver, but his impact in the running game has diminished -- no runs longer than 14 yards over the last nine games. Greene is younger and has fresher legs, and his bruising, north-south running style is conducive to cold-weather football. Inexplicably, the coaches forgot about him in the fourth quarter of Sunday's loss. That should serve as a lesson for upcoming games.
• Copy the Pats: Veteran observers noticed Sunday that the Jets tried to use the same game plan that worked so well for the New England Patriots in their recent rout of the Chicago Bears. In short: a quick-passing game. A lot of slant routes. At least a dozen plays out of the shotgun, including a couple of draw plays. Throwing out of two-tight end packages. Stuff like that.
It worked. It was the Jets' best offensive game in a month, and perhaps their most complete game -- start to finish -- since the win at Buffalo in October. Coordinator Brian Schottenheimer may have found something, and he should stick with it. He doesn't have Tom Brady (or Danny Woodhead, for that matter), but he can copy the Pats' plan.
"I think we're going to be a tough offense to handle," said Ryan, looking ahead to the postseason.
• More Rex on D: It's impossible to tell how much of the play calling on defense is Ryan and how much is coordinator Mike Pettine, who has assumed a larger role in that area. They would have us believe it's one brain and two mouths. Whatever it is, it's not working on a consistent basis. They need to go back to the way it was last season, which means Ryan calling all the plays.
No, the defense isn't in shambles, as some suggested in the aftermath of Sunday's 38-34 loss, but there's no doubt this unit is underachieving. Talent-wise, man for man, it's better on paper than last season's league-leading defense. But the results aren't there. The Jets are ranked 11th in scoring defense and, unlike last season, they can't attribute some of it to Sanchez's pick sixes. In fact, he has none.
There have been too many communication breakdowns (i.e. 10 men on the field), too many bad matchups (Jason Taylor in pass coverage) and too many predictable calls. The Bears said they tried more vertical passes in the second half because they knew the Jets would be in straight man-to-man.
"We got put into situations that weren't the best," linebacker Calvin Pace said after the game, making comments that could be interpreted as veiled criticism of the coaches. "It's frustrating because I know the type of players we have. We're in the playoffs and that's all I have to say about that."
• Forget the gadgets: The fake punt, with Sanchez as the "up" back, was a terrible call on every level. If you put a quarterback in punt formation, you might as well hold up a sign that says, "Here comes the fake." Another head-scratcher was having Brad Smith throw long in the fourth quarter of a four-point game.
The Jets don't need gimmicks. They're a meat-and-potatoes team. And they're a good team. They didn't win 10 games by accident. If the quarterback's shoulder is OK, and if Ryan can fix the defense overnight, the Jets can be more than one-and-done in the playoffs. It'll take a good wing and a prayer.
Rich Cimini covers the Jets for ESPNNewYork.com. Follow him on Twitter.
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The wheels are in motion to stop farmers dragging mud onto South Canterbury roads.
District councils in South Canterbury are working with farmers to keep roads safe and mud free.
The problem arises when farm vehicles working in paddocks during wet conditions become caked with mud which is then dropped on public roads.
Early rains and the change of farming activity in the winter meant it was particularly bad this year.
Waimate District Council roading asset manager Rob Moffat said there were 20 areas in Waimate affected by extreme dumping of mud.
"It is damaging the road in the longer term, damaging the drainage - and the mud [on the roads] is hazardous to the public."
He said it was an ongoing problem that may not be completely resolved, but the council was working with Federated Farmers and road safety co-ordinator Daniel Naude to come up with guidelines of how farmers could prevent it happening.
Roads around the Levels area near Timaru also had the same problem.
Timaru District Council land transport manager Andrew Dixon said it was about working with farmers, not against them.
He said it was a fairly common problem at this time of year but roads needed to be safe.
In a message to its members, South Canterbury Federated Farmers said it had spoken to district council roading engineers and police representatives.
The council, through its bylaws, or the police, through traffic regulations, could issue infringement notices for "the depositing of a substance on the road that could endanger other road users".
It said neither organisation, recognising the problems faced by farmers this year in regards to wet conditions, wanted to start issuing infringement notices.
Some suggestions to combat the problem from Federated Farmers in conjunction with the councils, were the physical removal of the material on the road by the farmers responsible, or, if they were unable to clear it, a council contractor could be arranged to clean the affected area and provide road warning signs.
- The Timaru Herald
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OPINION: Why aren't power prices falling?
From the "history always repeats" department come recent breathless reports that allegedly "lift the lid" on over-charging for electricity over the past 25 years.
Actually, there's nothing new about this claim. It's just that a new generation of journalists has caught up with it.
The argument is this: electricity companies have continually revalued their assets upwards and raised their tariffs accordingly, to reflect reasonable rates of return on capital.
It's a disarmingly simple argument. But it doesn't stack up.
The revaluations were prompted by the fact that every new power station produces electricity at greater cost than the last one. Power prices have been rising to reflect the cost of the next unit of supply.
Of course, many see this as a self-interested scam in a vertically integrated industry that faces no competition from overseas and comparatively little in New Zealand, in what looks like the same cosy arrangements as are alleged of banks and petrol stations.
This version of reality says that if everyone's charging the same price, they must be colluding. The trouble is, the opposite is true of commodities like mortgages, petrol and electricity.
That's why the Electricity Authority's hugely successful "What's My Number?" campaign seeks "price convergence", where every power company charges much the same because price gougers lose customers.
Some critics believe power companies should base their prices on what their assets cost to build - another flawed argument, since no other industry operates that way. They price on the basis of supply and demand and hope to make a margin.
The reality for most of the past 27 years, since the New Zealand Electricity Department stopped being a government department and started being a business, is that demand for electricity has risen.
That meant new power stations were needed, and unless power companies can be sure they will earn a return on new plant, they simply won't build such capital-intensive long-lived assets.
Each new power station has got to the front of the queue simply by being the next cheapest option available.
In the late 1990s and early 2000s, natural gas won that race. More latterly, wind and geothermal options have been the next cheapest options at costs of about $85 to $100 a Megawatt hour.
However, for the past five years, the key element that kept power prices rising has disappeared. There has been virtually no growth in demand.
Although a rash of new wind and geothermal developments has occurred in that time, no major generator plans to build new capacity any time soon, and tumbleweed now blows down the corridors where, just a couple of years ago, bands of engineers worked on the next big project.
Moreover, consumption may weaken before it grows again as industrial electricity users contract or turn to gas and coal. Norske Skog has closed the newsprint plant at its Kawerau facility, while the majority owner of the Bluff aluminium smelter, Rio Tinto, is strong-arming for a lower price on its contracts, which account for about a seventh of total electricity consumption.
It's unlikely the smelter will close, but even reduced production could produce slack in the system for some time to come.
Meanwhile, over the past six to 12 months, wholesale electricity prices have been weak, consistently below the $85 to $100 per MWh "long run marginal price" used to justify new geothermal and wind projects.
In other words, the wholesale market at present isn't delivering the prices on which the power company valuations are based and, for the first time in a long time, the electricity industry looks like a price-taker rather than a price-maker.
So why aren't electricity prices falling yet? The power companies argue, with some justification, that the huge cost of upgrading the national grid, run by the state-owned monopoly Transpower, has to be passed through to consumers, along with rising costs of local distribution.
They also argue, with some justification, that fixed tariffs protect consumers from the sometimes wild swings in the wholesale electricity spot market. With only six weeks of hydro storage, it takes only a prolonged dry spell to push wholesale prices up.
Today, however, those fixed tariffs might be argued to be "protecting" consumers from persistently low wholesale prices. If those price trends are sustained, then the case for higher energy charges is weak.
The Electricity Authority is watching all this closely. At a briefing last week, chief executive Carl Hansen cited both "massive changes in view about weakness of demand" and evidence from the futures market of a "very stable wholesale price outlook".
Futures prices for 2015 had dropped an average 26 per cent in recent months from $120 per Megawatt hour to $90 per MWh and there was "no way" price rises could be justified in that environment.
Of course, when the economic and electricity demand growth resume, that downward pressure will ease. In the meantime, it looks as if the reasons power companies have always given for raising prices are now available to use against them. BusinessDesk
Disclosure: Pattrick Smellie worked for Contact Energy between 2002 and 2008.
- BusinessDesk
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The 'Star Wars: Episode VII -- The Force Awakens' director reveals to Jon Stewart how the Millennium Falcon door that injured Harrison Ford on set also broke Abrams' back.


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text: Second time coming to the place and it fit our needs perfectly. Not too expensive and had what you need so you don't have to eat out every meal. Close to Silver Dollar City and close to a public beach although it was closed due to high water. Somewhat dated but functional. If what you are looking for is a... More


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Monasterio de piedras
... depending on their status. Then going into the church part, you see the damage that was done during the different shifts if power. The church literally has no roof. It's quite pretty in the bright sunlight.
After having a picnic lunch, my Spanish friend Demelsa, her boyfriend and I went through the rest of the park. It is a park full of waterfalls, ponds, and green space. You feel like you are walking into a story ...
Tasting the Difference
... I had calamari and papas bravas, but the calamari was thick and chewy and the papas bravas was just fried potato chunks caked in spicy ketchup and mayonnaise, I actually had to search for the potato! The city was like a ghost town from 2pm til 4pm with everyone in the bars enjoying the Spanish siesta. I have to admit it's something I just can't get used to, I feel more tired after a two hour lunch than before! I do like the ...
En route to Barcelona
... the bus with a local guide (Eva) at 5. Big place with a lot of old and new. Drove up to the cathedral which was started in 1882 and still going. Blows your mind away. Gauldi was the architect and was 31 when he started (1883) hedged in a car accident in 1926 at the age of 74, however he had left his drawings and had a model of how he wanted it to look, so they ...
Day 7: Alcala de Henares to Monreal de Ariza
We rolled another 198k under our wheels today but, as before, not all of them have been entirely productive. We woke to rain but thankfully it stopped before we set out at 07:00. The ride to the control town of Guadalajara was uneventful enough apart from having to mend our second puncture of the trip on the hard shoulder of a short motorway section - it seems even the finest kevlar belted tyres are no match for what looked like ...
Los Reyes Magos Parade and the Vineyard visit
... and has a few dried fruit on the top. Inside, there are a couple of surprises to find. One is the good surprise, a little figurine. The other is like a "piece of coal" which means that you get to buy the Roscon next year.
That weekend, we went to the grandparents house to see the parade because it passed right in front. We could watch it from the balcony. There were so many people. It was neat and reminded me of the Santa ...


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Journal of molecular biology [journal]
30011 results
- DNA-segment-facilitated dissociation of Fis and NHP6A from DNA detected via single-molecule mechanical response. [JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 25.
The rate of dissociation of a DNA-protein complex is often considered to be a property of that complex, without dependence on other nearby molecules in solution. We study the kinetics of dissociation of the abundant E. coli nucleoid protein Fis from DNA, using a single-molecule mechanics assay. The rate of Fis dissociation from DNA is strongly dependent on the solution concentration of DNA. The off-rate (koff) of Fis from DNA shows an initially linear dependence on solution DNA concentration, characterized by an exchange rate of kex≈9×10(-4)s(-1) (ng/μl)(-1) for 100mM univalent salt buffer, with a very small off-rate at zero DNA concentration. The off-rate saturates at approximately koff,max≈9×10(-3)s(-1) for DNA concentrations above≈20ng/μl. This exchange reaction depends mainly on DNA concentration with little dependence on the length of the DNA molecules in solution or on binding affinity, but does increase with increasing salt concentration. We also show data for the yeast HMGB protein NHP6A showing a similar DNA-concentration-dependent dissociation effect, with faster rates suggesting generally weaker DNA binding by NHP6A relative to Fis. Our results are well-described by a model with an intermediate partially-dissociated state where the protein is susceptible to being captured by a second DNA segment, in the manner of "direct transfer" reactions studied for other DNA-binding proteins. This type of dissociation pathway may be important to protein-DNA binding kinetics in vivo where DNA concentrations are large.
- Structures of the ultra-high affinity protein-protein complexes of pyocins S2 and AP41 and their cognate immunity proteins from Pseudomonas aeruginosa. [JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 24.
- AbstractPublisher Full Text
How ultra-high affinity protein-protein interactions retain high specificity is still poorly understood. The interaction between colicin DNase domains and their inhibitory immunity (Im) proteins is an ultra-high affinity interaction that is essential for the neutralisation of endogenous DNase catalytic activity and for protection against exogenous DNase bacteriocins. The colicin DNase-Im interaction is a model system for the study of high affinity protein-protein interactions. However, despite the fact that closely related colicin-like bacteriocins are widely produced by Gram-negative bacteria this interaction has only been studied using the colicins from Escherichia coli. In this work, we present the first crystal structures of two pyocin DNase-Im complexes from Pseudomonas aeruginosa, pyocin S2 DNase-ImS2 and pyocin AP41 DNase-ImAP41. These structures represent divergent DNase-Im subfamilies and are important in extending our understanding of protein-protein interactions for this important class of high affinity protein complex. A key finding of this work is that mutations within the immunity protein binding energy hotspot, helix III, are tolerated by complementary substitutions at the DNase-immunity protein binding interface. Im helix III is strictly conserved in colicins where an Asp forms polar interactions with the DNase backbone. ImAP41 contains an Asp-to-Gly substitution in helix III and our structures show the role of a co-evolved substitution where Pro in DNase loop 4 occupies the volume vacated and removes the unfulfilled hydrogen bond. We observe the co-evolved mutations in other DNase-immunity pairs that appear to underpin the split of this family into two distinct groups.
- Epigenetic Modulation of Human Podocyte Vitamin D Receptor in HIV milieu. [JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 22.
- AbstractPublisher Full Text
HIV has been reported to induce podocyte injury through down regulation of vitamin D receptor (VDR) and activation of renin angiotensin system (RAS); however, the involved mechanism is not clear. Since HIV has been reported to modulate gene expression via epigenetic phenomena, we asked whether epigenetic factors are contributing to down regulation of VDR. Kidney cells in HIV transgenic mice as well as HIV-infected podocytes (HIV/HPs) displayed enhanced expression of SNAIL, a repressor of VDR. To elucidate the mechanism, we studied the effect of HIV on expression of molecules involved in SNAIL repressor complex formation and demonstrated that HIV enhancesexpression of histone deacetylase (HDAC) 1, DNA methyl transferase (DNMT) 3b and DNMT1. 293T cells, when stably transfected with SNAIL (SNAIL/293T), displayed suppressed transcription and translation of VDR. In SNAIL/293T cells, co-immunoprecipitation studies revealed the association of HDAC1, DNMT3b, DNMT1, and mSin3A with SNAIL. Chromatin immunoprecipitation (ChIP) experiments confirmed the presence of the SNAIL repressor complex at the VDR promoter. Consistent with the enhanced DNA methyl transferase expression in HIV/HPs, there was an increased CpG methylation at the VDR promoter. ChIP assay confirmed occurrence of H3K4 trimethylation on SNAIL promoter. Neither VDR agonist (VDA) nor an HDAC inhibitor (HDACI) nor demethylating agent (DAC) individually could optimally upregulate VDR in HIV milieu. However, VDA and HDACI when combined were successful in de-repressing VDR expression. Our findings demonstrate that SNAIL recruits multiple chromatin enzymes to form a repressor complex in HIV milieu which down regulates VDR expression.
- Structure/function analysis of protein-protein interactions developed by the yeast Pih1 platform protein and its partners in box C/D snoRNP assembly. [JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 22.
- AbstractPublisher Full Text
In eukaryotes, nucleotide post-transcriptional modifications in RNAs play an essential role in cell proliferation by contributing to pre-ribosomal RNA processing, ribosome assembly and activity. box C/D snoRNPs catalyze site-specific 2'-O-methylation of riboses, one of the most prevalent RNA modifications. They contain one guide RNA and four core proteins and their in vivo assembly requires numerous factors including (HUMAN/Yeast): BCD1/Bcd1p, NUFIP1/Rsa1p, ZNHIT3/Hit1p, the R2TP complex composed of proteins PIH1D1/Pih1p, and RPAP3/Tah1p which bridges the R2TP complex to the HSP90/Hsp82 chaperone, and two AAA+ ATPases. We show that Tah1p can stabilize Pih1p in the absence of Hsp82 activity during the stationary phase of growth and consequently that the Tah1p:Pih1p interaction is sufficient for Pih1p stability. This prompted us to establish the solution structure of the Tah1p:Pih1p complex by NMR. The C-terminal tail S93-S111 of Tah1p snakes along Pih1p264-344 folded in a CS domain to form two intermolecular β-sheets and one covering loop. However, a thorough inspection of the NMR and crystal structures revealed structural differences that may be of functional importance. In addition, our NMR and ITC data revealed the formation of direct contacts between Pih1p257-344 and the Hsp82MC domain in the presence of Tah1p. By co-expression in E. coli, we demonstrate that Pih1p has two other direct partners, the Rsa1p assembly factor and the Nop58p core protein, and in vivo and in vitro experiments mapped the required binding domains. Our data suggest that these two interactions are mutually exclusive. The implication of this finding for box C/D snoRNP assembly is discussed.
- Formation of tertiary interactions during rRNA GTPase center folding. [JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 22.
- AbstractPublisher Full Text
The 60 nucleotide GTPase center (GAC) of 23S rRNA has a phylogenetically conserved secondary structure with two hairpin loops and a 3-way junction. It folds into an intricate tertiary structure upon addition of Mg(2+) ions, which is stabilized by the L11 protein in cocrystal structures. Here we monitor the kinetics of its tertiary folding and Mg(2+)-dependent intermediate states by observation of selected nucleobases that contribute specific interactions to the GAC tertiary structure in the cocrystals. The fluorescent nucleobase 2-aminopurine (2AP) replaced three individual adenines, two of which make long-range stacking interactions, and one that also forms hydrogen bonds. Each site reveals a unique response to Mg(2+) addition and temperature, reflecting its environmental change from secondary to tertiary structure. Stopped-flow fluorescence experiments revealed that kinetics of tertiary structure formation upon addition of MgCl2 are also site-specific, with local conformational changes occurring from 5 ms - 4 s, and with global folding from 1- 5 s. Site-specific substitution with (15)N-nucleobases allowed observation of stable hydrogen bond formation by NMR experiments. Equilibrium titration experiments indicate that a stable folding intermediate is present at stoichiometric concentrations of Mg(2+), and suggest that there are two initial sites of Mg(2+) ion association.
- Structures of DegQ from Legionella pneumophila define distinct ON and OFF states. [JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 20.
- AbstractPublisher Full Text
HtrA family proteins play important roles in protein-quality control processes in the bacterial periplasm. A common feature of all members of this family is their modular organisation comprising a chymotrypsin-like protease domain and at least one PDZ domain. All characterized HtrA proteins assemble into complex oligomers consisting of typically 3 to 24 monomers, which allow a tight regulation of proteolytic activity. Here, we provide evidence that the assembly of proteolytically active, higher-order complexes of DegQ from Legionella pneumophila is triggered by the binding of substrate-derived peptides. Crystal structures of inactive 3-mers and active 12-mers of DegQ reveal molecular details of elements of a conserved allosteric activation cascade that defines distinct protease ON and OFF states. Results from DegQLp variants harbouring structure-based amino-acid substitutions indicate that peptide binding to the PDZ1 domain is critical for proteolytic activity but not for the formation of higher-order oligomers. Combining structural, mutagenesis and biochemical data, we show that in contrast to the proteolytic activity, the chaperone function of DegQ is not affected by the state of the activation cascade.
- The modulatable stem cell niche: Tissue interactions during hair and feather follicle regeneration. [REVIEW, JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 18.
- AbstractPublisher Full Text
Hair and feathers are unique because 1) their stem cells are contained within a follicle structure, 2) they undergo cyclic regeneration repetitively throughout life, 3) regeneration occurs physiologically in healthy individuals and 4) regeneration is also induced in response to injury. Precise control of this cyclic regeneration process is essential for maintaining the homeostasis of living organisms. While stem cells are regulated by the intra-follicle adjacent micro-environmental niche, this niche is also modulated dynamically by extra-follicular macro-environmental signals, allowing stem cells to adapt to a larger changing environment and physiological needs. Here we review several examples of macro-environments that communicate with the follicles: intradermal adipose tissue, innate immune system, sex hormones, aging, circadian rhythm and seasonal rhythms. Related diseases are also discussed. Unveiling the mechanisms of how stem cell niches are modulated provides clues for regenerative medicine. Given that stem cells are hard to manipulate, focusing translational therapeutic applications at the environments appears to be a more practical approach.
- Acidic residues in the Hfq chaperone increase the selectivity of sRNA binding and annealing. [JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 18.
- AbstractPublisher Full Text
Hfq facilitates gene regulation by small non-coding RNAs (sRNAs), thereby affecting bacterial attributes such as biofilm formation and virulence. E. coli Hfq recognizes specific U-rich and AAN motifs in sRNAs and target mRNAs, after which an arginine patch on the rim promotes base pairing between their complementary sequences. In the cell, Hfq must discriminate between many similar RNAs. Here, we report that acidic amino acids lining the sRNA binding channel between the inner pore and rim of the Hfq hexamer contribute to the selectivity of Hfq's chaperone activity. RNase footprinting, in vitro binding and stopped-flow fluorescence annealing assays showed that alanine substitution of D9, E18 or E37 strengthened RNA interactions with the rim of Hfq and increased annealing of non-specific or U-tailed RNA oligomers. Although the mutants were less able than WT Hfq to anneal sRNAs with wild type rpoS mRNA, the D9A mutation bypassed recruitment of Hfq to an (AAN)4 motif in rpoS, both in vitro and in vivo. These results suggest that acidic residues normally modulate access of RNAs to the arginine patch. We propose that this selectivity limits indiscriminate target selection by E. coli Hfq, and enforces binding modes that favor genuine sRNA and mRNA pairs.
- A regulated, ubiquitin-independent degron in IκBα. [JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 17.
- AbstractPublisher Full Text
Whereas ubiquitin-dependent degrons have been characterized in some detail, how proteins may be targeted to ubiquitin-independent proteasomal degradation remains unclear. Here we show that IκBα contains a ubiquitin-independent degron whose activity is portable to heterologous proteins such as the globular protein GFP via a proteasome-dependent, ubiquitin-independent, non-lysosomal pathway. The ubiquitin-independent degradation signal resides in a 11 amino acid sequence, which is not only sufficient but also required for IκBα's short half-life. Finally, we show that this degron's activity is regulated by the interaction with NFκB, which controls its solvent exposure, and we demonstrate that this regulation of the degron's activity is critical for IκBα's signaling functions.
- Brainless but Multi-Headed: Decision Making by the Acellular Slime Mould Physarumpolycephalum. [REVIEW, JOURNAL ARTICLE]
- J Mol Biol 2015 Jul 17.
- AbstractPublisher Full Text
Because of its peculiar biology and the ease with which it can be cultured, the acellular slime mould Physarum polycephalum has long been a model organism in a range of disciplines. Due to its macroscopic, syncytial nature, it is no surprise that it has been a favourite amongst cell biologists. Its inclusion in the experimental tool kit of behavioural ecologists is much more recent. These recent studies have certainly paid off. They have shown that, for an organism that lacks a brain or central nervous system, P. polycephalum shows rather complex behaviour. For example, it is capable of finding the shortest path through a maze, it can construct networks as efficient as those designed by humans, it can solve computationally difficult puzzles, it makes multi-objective foraging decisions, it balances its nutrient intake and it even behaves irrationally. Are the slime mould's achievements simply "cute", worthy of mentioning in passing but nothing to take too seriously? Or do they hint at the fundamental processes underlying all decision making? We will address this question after reviewing the decision-making abilities of the slime mould.


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|By Business Wire
Article Rating:
|December 9, 2013 08:02 AM EST
According to the Centers for Disease Control and Prevention (CDC), diabetes affects 25.8 million Americans. If trends continue, more than a third of the country will have the disease by 2050. In 2012, the estimated total cost of diagnosed diabetes in the United States was $245 billion.
To help patients, physicians, employers, and health plans better address this growing epidemic, Telcare, Inc., the leader in mobile diabetes management solutions, and Health Dialog, a preeminent provider of care management, today announced a strategic partnership. Under terms of the agreement, Telcare's blood glucose monitor (BGM) will integrate with Health Dialog's diabetes management program, providing patients living with diabetes and their healthcare providers a more effective way to manage and control the chronic condition.
"The rising prevalence of diabetes and the associated costs require organizations and patients adopt new, accountable measures for controlling diabetes in order to prevent needless complications," said Dr. Jonathan Javitt, co-founder and CEO of Telcare and the inventor of Telcare's diabetes monitoring system. "Our technology, coupled with the already-successful Health Dialog diabetes management program, will give organizations an innovative way to treat the condition, and we are looking forward to the partnership," said John Dwyer, Telcare's Chairman and co-founder.
Using glucose values transmitted in real-time by the Telcare BGM, patients now have instant access to feedback and coaching for their condition. Caregivers and providers have online access to the same results, allowing them to easily analyze the data and get alerts about potential patient complications. Additionally, patients no longer need to keep a log of their blood glucose readings to convey to their provider. Providers can spend more time during patient appointments focusing on treatment and less time reviewing blood glucose levels.
"Much of healthcare today involves helping people manage conditions, including diabetes, whose outcomes can be greatly influenced by lifestyle or behaviors," said Robert Mandel, M.D., CEO of Health Dialog. "The addition of Telcare's cellular-enabled glucose monitoring device to our proven diabetes management program provides our clients with access to real-time blood glucose data to help patients and caregivers monitor and act in a timely manner and, ultimately, change behavior so that they can live healthier, happier, longer lives."
To learn more about the Telcare and Health Dialog partnership, visit Telcare in booth 813 at the mHealth Summit from December 9-11, 2013, in Washington, D.C. For more information about Telcare and its BGM, visit www.telcare.com. For information about Health Dialog, visit www.healthdialog.com.
About Telcare
Telcare enables health plans and employers to lower costs and improve outcomes for individuals living with diabetes by delivering actionable, real-time insight that promotes greater care coordination and engagement. The company's award-winning mobile health platform combines cellular-enabled technologies with personalized feedback and coaching to increase compliance with care guidelines and prevent complications, thereby improving population health and reducing the cost of care. Telcare is a privately-held company funded by the Qualcomm Life Fund, Sequoia Capital, and private investors. To learn more, visit www.telcare.com.
About Health Dialog Services Corporation:
Health Dialog Services Corporation is a leading provider of healthcare analytics and decision support. The firm is a private, wholly-owned subsidiary of Bupa, a global provider of healthcare services. Health Dialog helps employers, payers, and providers improve healthcare quality while reducing overall costs. Company offerings include health coaching for medical decisions, chronic conditions, and wellness; population analytic solutions; and consulting services. Health Dialog helps individuals participate in their own healthcare decisions, develop more effective relationships with their physicians, and live longer, healthier, happier lives. For more information, visit www.healthdialog.com.
SYS-CON Events announced today that MobiDev, a software development company, will exhibit at the 17th International Cloud Expo®, which will take place November 3–5, 2015, at the Santa Clara Convention Center in Santa Clara, CA. MobiDev is a software development company with representative offices in Atlanta (US), Sheffield (UK) and Würzburg (Germany); and development centers in Ukraine. Since 2009 it has grown from a small group of passionate engineers and business managers to a full-scale mobi...
Aug. 2, 2015 12:00 PM EDT Reads: 323
With SaaS use rampant across organizations, how can IT departments track company data and maintain security? More and more departments are commissioning their own solutions and bypassing IT. A cloud environment is amorphous and powerful, allowing you to set up solutions for all of your user needs: document sharing and collaboration, mobile access, e-mail, even industry-specific applications. In his session at 16th Cloud Expo, Shawn Mills, President and a founder of Green House Data, discussed h...
Aug. 2, 2015 11:45 AM EDT Reads: 469
For IoT to grow as quickly as analyst firms' project, a lot is going to fall on developers to quickly bring applications to market. But the lack of a standard development platform threatens to slow growth and make application development more time consuming and costly, much like we've seen in the mobile space. In his session at @ThingsExpo, Mike Weiner, Product Manager of the Omega DevCloud with KORE Telematics Inc., discussed the evolving requirements for developers as IoT matures and conducte...
Aug. 2, 2015 11:15 AM EDT Reads: 343
There are many considerations when moving applications from on-premise to cloud. It is critical to understand the benefits and also challenges of this migration. A successful migration will result in lower Total Cost of Ownership, yet offer the same or higher level of robustness. In his session at 15th Cloud Expo, Michael Meiner, an Engineering Director at Oracle, Corporation, analyzed a range of cloud offerings (IaaS, PaaS, SaaS) and discussed the benefits/challenges of migrating to each offe...
Aug. 2, 2015 11:00 AM EDT Reads: 152
One of the hottest areas in cloud right now is DRaaS and related offerings. In his session at 16th Cloud Expo, Dale Levesque, Disaster Recovery Product Manager with Windstream's Cloud and Data Center Marketing team, will discuss the benefits of the cloud model, which far outweigh the traditional approach, and how enterprises need to ensure that their needs are properly being met.
Aug. 2, 2015 09:00 AM EDT Reads: 1,695
In their session at 17th Cloud Expo, Hal Schwartz, CEO of Secure Infrastructure & Services (SIAS), and Chuck Paolillo, CTO of Secure Infrastructure & Services (SIAS), provide a study of cloud adoption trends and the power and flexibility of IBM Power and Pureflex cloud solutions. In his role as CEO of Secure Infrastructure & Services (SIAS), Hal Schwartz provides leadership and direction for the company.
Aug. 2, 2015 08:15 AM EDT Reads: 169
In a recent research, analyst firm IDC found that the average cost of a critical application failure is $500,000 to $1 million per hour and the average total cost of unplanned application downtime is $1.25 billion to $2.5 billion per year for Fortune 1000 companies. In addition to the findings on the cost of the downtime, the research also highlighted best practices for development, testing, application support, infrastructure, and operations teams.
Aug. 2, 2015 07:00 AM EDT Reads: 174
"We've just seen a huge influx of new partners coming into our ecosystem, and partners building unique offerings on top of our API set," explained Seth Bostock, Chief Executive Officer at IndependenceIT, in this SYS-CON.tv interview at 16th Cloud Expo, held June 9-11, 2015, at the Javits Center in New York City.
Aug. 1, 2015 09:00 PM EDT Reads: 669
SYS-CON Events announced today that HPM Networks will exhibit at the 17th International Cloud Expo®, which will take place on November 3–5, 2015, at the Santa Clara Convention Center in Santa Clara, CA. For 20 years, HPM Networks has been integrating technology solutions that solve complex business challenges. HPM Networks has designed solutions for both SMB and enterprise customers throughout the San Francisco Bay Area.
Aug. 1, 2015 04:45 PM EDT Reads: 496
The Software Defined Data Center (SDDC), which enables organizations to seamlessly run in a hybrid cloud model (public + private cloud), is here to stay. IDC estimates that the software-defined networking market will be valued at $3.7 billion by 2016. Security is a key component and benefit of the SDDC, and offers an opportunity to build security 'from the ground up' and weave it into the environment from day one. In his session at 16th Cloud Expo, Reuven Harrison, CTO and Co-Founder of Tufin,...
Aug. 1, 2015 03:00 PM EDT Reads: 527
Mobile, social, Big Data, and cloud have fundamentally changed the way we live. "Anytime, anywhere" access to data and information is no longer a luxury; it's a requirement, in both our personal and professional lives. For IT organizations, this means pressure has never been greater to deliver meaningful services to the business and customers.
Aug. 1, 2015 11:15 AM EDT Reads: 191
Container technology is sending shock waves through the world of cloud computing. Heralded as the 'next big thing,' containers provide software owners a consistent way to package their software and dependencies while infrastructure operators benefit from a standard way to deploy and run them. Containers present new challenges for tracking usage due to their dynamic nature. They can also be deployed to bare metal, virtual machines and various cloud platforms. How do software owners track the usag...
Aug. 1, 2015 10:30 AM EDT Reads: 222
The Internet of Everything (IoE) brings together people, process, data and things to make networked connections more relevant and valuable than ever before – transforming information into knowledge and knowledge into wisdom. IoE creates new capabilities, richer experiences, and unprecedented opportunities to improve business and government operations, decision making and mission support capabilities.
Aug. 1, 2015 10:00 AM EDT Reads: 329
Chuck Piluso presented a study of cloud adoption trends and the power and flexibility of IBM Power and Pureflex cloud solutions. Prior to Secure Infrastructure and Services, Mr. Piluso founded North American Telecommunication Corporation, a facilities-based Competitive Local Exchange Carrier licensed by the Public Service Commission in 10 states, serving as the company's chairman and president from 1997 to 2000. Between 1990 and 1997, Mr. Piluso served as chairman & founder of International Te...
Aug. 1, 2015 09:45 AM EDT Reads: 400
Puppet Labs has announced the next major update to its flagship product: Puppet Enterprise 2015.2. This release includes new features providing DevOps teams with clarity, simplicity and additional management capabilities, including an all-new user interface, an interactive graph for visualizing infrastructure code, a new unified agent and broader infrastructure support.
Aug. 1, 2015 09:45 AM EDT Reads: 197


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Outdoor Rug
Beautiful colors exactly as pictured and great quality that I would have paid triple for!
Wonderful rug
This beautiful rug has transformed our porch. It is well made, did not have any strong odor, and unrolled quickly. The colors are vibrant. I was pleasantly surprised at how soft it is. I had expected an indoor/outdoor rug to be stiff or plastic-y, but it is not. It would be suitable as an indoor rug also.
- How did the color on site compare with the actual product? very well
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From Justin To Kelly 2003 | Movie Watchlist
Set in during Spring Break revels and thrown together in record time some five months from start of principal photography to release this fluffy musical showcase for first-generation American Idol stars Kelly Clarkson and Justin Guarini is in constant danger of wafting away on an ocean breeze. Three Texas gal pals and three righteous dudes from Pennsylvania head to Miami in search of fun, sun and sex (though for all the skimpy outfits, the film's language and depiction of dating rituals wouldn't be out of place in a '60s beach party movie). The Lone Star sweeties are nice girl Kelly (Clarkson, who looks strikingly like a slightly plump, teenage Patty Duke), smart and sassy Kaya (Anika Noni Rose) and rich, back-stabbing barracuda Alexa (Katherine Bailess). The Penn State posse comprises nerd-boy Eddie (Brien Dietzen), wild man Brandon (Greg Siff) and reformed party animal Justin (Guarini). Justin and Brandon run BR&J party promotions and throw the wildest events in town, from whipped-cream bikini contests to tropical pool parties. When Justin and Kelly meet, it's kismet. But things keep messing up their romance, most of them engineered by self-proclaimed "Queen of Conniving" Alexa, who wants Justin for herself. Meanwhile Kaya falls for a sweet-natured Cuban waiter (Jason Yribar) and Brandon keeps running afoul of a local cop (Theresa San Nicholas) who needs only let down her hair and trade her starchy uniform for a sarong to undergo an "Officer Cutler, you're gorgeous" transformation. Poor Eddie is constantly thwarted in his efforts to find his cyber-crush, Lizzie (Toi Svan Stepp); the two have arranged to meet face-to-face after a year of online flirting, but keep missing each other. Directed by Robert Iscove (who lost the opportunity to direct CHICAGO to Rob Marshall and apparently doesn't care who knows he's mad about it), this too-many-generations-removed copy of WHERE THE BOYS ARE (1960) is crammed with energetic but artless musical numbers that feature lip-synching multitudes and uninspired choreography. Clarkson and Guarini are both charmingly unaffected, but they're not movie stars; without the American Idol stamp of approval they'd be lucky to get cast as best friend. The music is lavishly overproduced pop pablum of the first order, and there's a deeply shallow irony in the fact the film's most memorable tune, KC and the Sunshine Band's 28-year-old "That's the Way I Like It," is easily twice the age of its target audience.
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- Released: 2003
- Rating: PG
- User Rating:
- Review: Set in during Spring Break revels and thrown together in record time some five months from start of principal photography to release this fluffy musical showcase for first-generation American Idol stars Kelly Clarkson and Justin Guarini is in… (more)
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The annual SIGGRAPH conference is a five-day interdisciplinary educational experience in the latest computer graphics and interactive techniques including a three-day commercial exhibition that attracts hundreds of exhibitors from around the world.
Advance Program
Detailed information on who's speaking and what's happening when in most programs and events. A great planning resource for a week of learning and interaction with tomorrow's technologies.
Technical Papers
Lights, shadows, forms, flows, algorithms, physics, math, elegant aesthetics, and intellectual adventures.
Production Sessions
The world's most elite and talented computer graphics experts explain their processes and techniques for creating compelling content.
SIGGRAPH Next
Distinguished thought-leaders assess how SIGGRAPH technologies will play an impactful role in tomorrow's reality.
Register Online Today
Meet your friends and colleagues at the "Xroads of Discovery" for a week of robust learning, exploration, and inspiration. Register early and save!
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Los Angeles
Downtown Los Angeles is enjoying a remarkable revitalization. Among the palm trees and sunshine are a number of residential and commercial endeavors, fantastic restaurants, and a new zest for life.
@borisfx teams with @ImagineerSys to present awesome new time-saving technologies and #vfx tools. http://t.co/PayJIq6UW8 #SIGGRAPH2015
@Disney RSR presents a sampling-based FWK for processing video enabling HQ #VFX in the presence of errors in depth. http://t.co/byAwOJTY6r
#TechTip: Learn how to use plane tracking in @blender3d & experiment w/ the possibilities it gives for quick #VFX. http://t.co/a74MkE3inw
#SIGGRAPH2015's Games Focus Program looks at the synergy btw the games industry and the #CG Comm to deliver content. http://t.co/C6VQz1heiy
There's a lot to see at #SIGGRAPH2015! Download the official SIGGRAPH mobile app & plan your time at the Conference. http://t.co/pnmSVD5WiD
#SIGGRAPH2015 Studio Chair Reid Baker invites you to explore alternative fields utilizing new foundations in #CG. http://t.co/LANya7lyYf
Floating b/w jobs? Register w/the #SIGGRAPH2015 Unemployed Discount: http://t.co/0YD5k4NkU5. {Then, check out the Job Fair!}
.@DisneyPixar's "Lava" gets limited DMA release: http://t.co/RETApaSKch. {So you can watch it b4 #SIGGRAPH2015's Production Session!}
8 days till we're together in L.A.! More about our host city: http://t.co/00vWbkGwJn. #SIGGRAPH2015 #DiscoverLA @ConventionLA
VR: A Beyond Games game-changer. http://t.co/ki5X8xdINo {Just wait till #SIGGRAPH2015...} [cc: @FastCompany]
Days Until SIGGRAPH 2015
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