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Gynacological Cancers
Gynaecological cancers are a group of different malignancies of the female reproductive system. The most common types of gynaecologic malignancies are cervical cancer, ovarian cancer, and endometrial (uterus) cancer. There are other less common gynaecological malignancies including cancer of the vagina, cancer of the vulva, gestational trophoblastic tumours, and fallopian tube cancer. Occasionally skin cancers or sarcomas can also be found in the female genitalia. Generally, most gynaecological cancers are found in women aged over 50, though the incidence rates for younger women have been rising.
Cervical Cancer
Endometrial (Uterus) Cancer
Fallopian Tube Cancer
Gestational Trophoblastic Cancer
Ovarian Cancer
Vaginal Cancer
Vulva Cancer
Uterine Sarcoma
Gynecologic Oncology (specialty)
General Gynacological Cancer Resources
Latest Research Publications
General Gynacological Cancer Resources (15 links)
International Gynecologic Cancer Society
A not for profit independent membership organization contributing to the prevention, treatment and study of gynecologic cancer, and improving the quality of life among women suffering from gynecologic cancer. Founded 1985.
Asian Society of Gynecologic Oncology
ASGO was founded in 2009 as the principal organization In Asia contributing to thestudy, Prevention and treatment of gynecological cancer.
Female Genital Tract Pathology
WebPath - Mercer University School of Medicine
Pathology Images - including some cancer related.
A non-profit organisation founded in 1991 to increase awareness and education, support expanded research and training, and provide knowledge and hope for women diagnosed with cancers specific to them.
GYN-ONC - Gynecological Cancers Support Group
Email discussion list
Official publication of the Society of Gynecologic Oncology. An international journal, is devoted to the publication of clinical and investigative articles that concern tumors of the female reproductive tract.
Gynecologic Oncology Case Reports
Peer reviewed online-only, Open Access journal devoted to the rapid publication of case reports in gynecologic oncology.
A non-profit international organization with the purpose of promoting excellence in the quality and integrity of clinical and basic scientific research in the field of Gynecologic malignancies. GOG is funded by the National Cancer Institute (USA).
International Journal of Gynecological Cancer
Lippincott Williams & Wilkins
Journal of the International Gynecologic Cancer Society and the European Society of Gynaecological Oncology.
Journal of Gynecologic Oncology
Korean Society of Gynecologic Oncology
International peer reviewed journal. Official journal of the Asian Society of Gynecologic Oncology (ASGO) and the Korean Society of Gynecologic Oncology (KSGO).
Nätverket mot gynekologisk cancer | Network against gynecologic cancer - Svenska - Translate to English
A non-profit network of patients, family members providing support and raising awareness about gynecological cancers.
Northern Gynaecological Oncology Centre
A specialist surgical service for the diagnosis, staging, treatment and care of women with gynaecological cancer and is a surgical centre for the North of England Cancer Network.
Queensland Centre for Gynaecological Cancer
A state-wide service for the management of women with gynaecological cancer working in partnership with Queensland Health. QCGC also has a reseach branch loctaed in the Royal Brisbane and Women's Hospital.
Society of Gynecologic Nurse Oncologists
Membership organisation with about 600 registered nurses and associates.
Society of Gynecologic Oncology
A professional membership organisation encouraging research, providing education, raising standards of practice, advocating for patients and members and collaborating with other domestic and international organizations. US + international members.
Latest Research Publications
This list of publications is regularly updated (Source: PubMed).
The vaccine and cervical cancer screen (VACCS) project: acceptance of human papillomavirus vaccination in a school-based programme in two provinces of South Africa.
S Afr Med J. 2015; 105(1):40-3 [PubMed] Related Publications
OBJECTIVES: To investigate acceptance of school-based human papillomavirus (HPV) vaccination, as well as the information provided, methods of obtaining consent and assent, and completion rates achieved.
METHODS: Information on cervical cancer and HPV vaccination was provided to 19 primary schools in Western Cape and Gauteng provinces participating in the study. Girls with parental consent and child assent were vaccinated during school hours at their schools.
RESULTS: A total of 3 465 girls were invited to receive HPV vaccine, of whom 2 046 provided written parental consent as well as child assent. At least one dose of vaccine was delivered to 2 030 girls (99.2% of the consented cohort), while a total of 1 782 girls received all three doses. Sufficient vaccination was achieved in 91.6% of the vaccinated cohort. Of all invited girls, 56.9% in Gauteng and 50.7% in the Western Cape were sufficiently vaccinated.
CONCLUSION: This implementation project demonstrated that HPV vaccination is practical and safe in SA schools. Political and community acceptance was good, and positive attitudes towards vaccination were encountered. During the study, which mimicked a governmental vaccine roll-out programme, high completion rates were achieved in spite of several challenges encountered.
Small cell carcinoma of the uterine cervix: a case report and literature review.
Bol Asoc Med P R. 2015 Jan-Mar; 107(1):55-7 [PubMed] Related Publications
Whole-genome characterization of chemoresistant ovarian cancer.
Nature. 2015; 521(7553):489-94 [PubMed] Related Publications
Successful acupuncture treatment of uterine myoma.
Acta Clin Croat. 2014; 53(4):487-9 [PubMed] Related Publications
Clinico-epidemiological study of endometrial hyperplasia--a risk factor for the development of endometrial carcinoma?
Rev Med Chir Soc Med Nat Iasi. 2015 Jan-Mar; 119(1):154-61 [PubMed] Related Publications
MATERIAL AND METHODS: Our study aimed at highlighting objective criteria in establishing the morphological diagnosis and in evaluating the prognostic elements. The studied batch included 875 patients with endometrial hyperplasia and 263 patients with endometrial adenocarcinoma, who were admitted between 2003 and 2007, and the histopathologic diagnosis was obtained by processing the hysterectomy pieces. The presence of this tumour was at its highest level half-way through the study, which was in 2005.
RESULTS: According to the study, there was a higher proportion of patients with endometrial carcinoma from the urban environment (58.2%) than the ones from the rural environment (only 41.8%). Depending on their age, most cases of endometrial adenocarcinoma were diagnosed in 53-year old patients, with an average age of 58.94 years. Our study, made of the two batches of endometrial adenocarcinomas, shows that between the endometrial and non-endometrial adenocarcinoma there are significant differences related to the patients' age, the morphological aspect of the carcinoma, the architectural degree, the nuclear degree of tumours and the invasion in the myometrium.
CONCLUSIONS: Our study proves that endometrial hyperplasia is a frequent diagnosis in peri- and postmenopausal patients and is frequently identified following investigations for an abnormal uterine bleeding. The age of patients with endometrial carcinoma is an important prognostic factor independent of other parameters. The difference between complex hyperplasia with no atypias and complex hyperplasia with atypias is important, because atypical complex hyperplasia is considered the precursor of endometrial adenocarcinoma.
Hypercalcemic type of small cell carcinoma of the ovary.
Vojnosanit Pregl. 2015; 72(3):295-8 [PubMed] Related Publications
CASE REPORT: A 60-year-old woman, Caucasian, came to the doctor because of discomfort in the lower abdomen and pain of greater intensity in last few days. Ultrasound examination and CT scan of the abdomen confirmed the presence of large adnexal masses of cystic-solid appearance with the largest diameter of 13 cm, regular structure of the other gynecological organs, without verifying the existence of metastatic deposits. All the results of laboratory analysis gave normal values, except for calcium, which was elevated. Explorative laparotomy with complete hysterectomy, bilateral salpingo-oophorectomy, dissection of lymph nodes and omentectomy were conducted. Based on pathohistological analysis of the operative material, SCOC at FIGO Ia stage was diag- nosed. No complications were observed in a postsurgery period and after 10 days the patient was discharged in a good condition and with normal calcemia. The treatment was continued with concurrent radiotherapy and chemotherapy. However, in spite of overall treatment, the disease progressed, and the patient died of disseminated metastatic disease, 26 months after the diagnosis.
CONCLUSION: Small cell carcinoma localized in the ovary is generally a tumor category with bad prognosis depending on the stage of the disease.
Unifying screening processes within the PROSPR consortium: a conceptual model for breast, cervical, and colorectal cancer screening.
J Natl Cancer Inst. 2015; 107(6):djv120 [PubMed] Related Publications
Association of 42 SNPs with genetic risk for cervical cancer: an extensive meta-analysis.
BMC Med Genet. 2015; 16:25 [PubMed] Free Access to Full Article Related Publications
METHODS: Electronic searches of PubMed and Embase were conducted for all publications about the association between gene polymorphisms and cervical cancer. One-hundred and sixty-seven association studies were included in our research. For each SNP, three models (the allele, dominant and recessive effect models) were adopted in the meta-analysis. For each model, the effect summary odds ratio (OR) and 95% CI were calculated. Heterogeneity between studies was evaluated by Cochran's Q test. If the p value of Q test was less than 0.01, a random effect model was used; otherwise, a fixed effect model was used.
RESULTS: The results of our meta-analysis showed that: (1) There were 8, 2 and 8 SNPs that were significantly associated with cervical cancer (P < 0.01) in the allele, dominant and recessive effect models, respectively. (2) rs1048943 (CYP1A1 A4889G) showed the strongest association with cervical cancer in the allele effect model (1.83[1.57, 2.13]); in addition, rs1048943 (CYP1A1 A4889G) had a very strong association in the dominant and recessive effect model. (3) 15, 11 and 10 SNPs had high heterogeneity (P < 0.01) in the three models, respectively. (4) There was no published bias for most of the SNPs according to Egger's test (P < 0.01) and Funnel plot analysis. For some SNPs, their association with cervical cancer was only tested in a few studies and, therefore, might have been subjected to published bias. More studies on these loci are required.
CONCLUSION: Our meta-analysis provides a comprehensive evaluation of cervical cancer association studies.
Effect of structured teaching programme on VIA test for early detection and diagnosis of cervical cancer.
Nurs J India. 2014 Sep-Oct; 105(5):221-4 [PubMed] Related Publications
Increase of nuclear expression of metallothionein I/II in neoplastic transformation of the endomnetrium.
Ginekol Pol. 2015; 86(3):182-7 [PubMed] Related Publications
MATERIAL AND METHODS: The study material included paraffin-embedded endometrial cancer samples from 84 patients. The control group consisted of 52 non-neoplastic endometrium samples. Immunohistochemical reactions were performed using monoclonal antibodies against EGFR, MT 1/11 and Ki-67. Expression intensity of the tested proteins was assessed by computer image analysis software. Chi-square, Spearman's correlation, Mann-Whitney and Kruskal-Wallis tests were used for statistical analysis with Statistica 8.0 PL.
RESULTS: Strong expression of nMT was revealed in endometrial cancer cells in relation to benign hyperplasia (p<0.0017) and normal cells (p<0.001) of the endometrium. Statistically significant but weaker expressions in analogous relationships were observed for cMT Moreover higher grade of histological malignancy G was positively associated with increased expression of nMT (p=0.009).
CONCLUSIONS: Expression of nMT remains in distinct correlation with neoplastic transformation of the endometrium and histologic grades. Our results clearly indicate a need for further research on metallothionein expression in tumor cells.
Ovarian cancer HO-8910 cell apoptosis induced by crocin in vitro.
Nat Prod Commun. 2015; 10(2):249-52 [PubMed] Related Publications
Syringoma of vulva: an unusual presentation. Clinical, morphological and immunohistochemical aspects.
Invest Clin. 2015; 56(1):60-5 [PubMed] Related Publications
Ovarian cancer liver metastases--should we apply the principle of optimal cytoreduction to the liver? A review.
Hepatogastroenterology. 2015 Mar-Apr; 62(138):355-7 [PubMed] Related Publications
Sequential chemotherapy and radiotherapy in the sandwich method for advanced endometrial cancer: a meta-analysis.
Medicine (Baltimore). 2015; 94(16):e672 [PubMed] Related Publications
Correlation of histogram analysis of apparent diffusion coefficient with uterine cervical pathologic finding.
AJR Am J Roentgenol. 2015; 204(5):1125-31 [PubMed] Related Publications
SUBJECTS AND METHODS: This prospective study was approved by the institutional review board, and written informed consent was obtained. Seventy-three patients with cervical cancer (33-69 years old; 35 patients with International Federation of Gynecology and Obstetrics stage IB cervical cancer) and 38 patients (38-61 years old) with normal cervix or cervical benign lesions (control group) were enrolled. All patients underwent 3-T diffusion-weighted imaging (DWI) with b values of 0 and 800 s/mm(2). ADC values of the entire tumor in the patient group and the whole cervix volume in the control group were assessed. Mean ADC, median ADC, 25th and 75th percentiles of ADC, skewness, and kurtosis were calculated. Histogram parameters were compared between different pathologic features, as well as between stage IB cervical cancer and control groups.
RESULTS: Mean ADC, median ADC, and 25th percentile of ADC were significantly higher for adenocarcinoma (p = 0.021, 0.006, and 0.004, respectively), and skewness was significantly higher for squamous cell carcinoma (p = 0.011). Median ADC was statistically significantly higher for well or moderately differentiated tumors (p = 0.044), and skewness was statistically significantly higher for poorly differentiated tumors (p = 0.004). No statistically significant difference of ADC histogram was observed between lymphovascular space invasion subgroups. All histogram parameters differed significantly between stage IB cervical cancer and control groups (p < 0.05).
CONCLUSION: Distribution of ADCs characterized by histogram analysis may help to distinguish early-stage cervical cancer from normal cervix or cervical benign lesions and may be useful for evaluating the different pathologic features of cervical cancer.
Comparable outcome between endometrioid and non-endometrioid tumors in patients with early-stage high-grade endometrial cancer.
J Surg Oncol. 2015; 111(6):790-4 [PubMed] Related Publications
METHODS: A total of 123 patients diagnosed with early-stage high-grade endometrial cancer at the Dutch Comprehensive Cancer Centre South (CCCS) between January 2005 and December 2011 were included. All patients underwent abdominal hysterectomy and bilateral salpingo-oophorectomy. Patient and tumor characteristics, primary and adjuvant treatment, and outcome were analyzed.
RESULTS: After a median follow-up of 27.9 months, 27.6% (n = 34) of patients had recurrent disease. Distant recurrence rate was equal among endometrioid (14.5%), papillary serous (14.8%), and clear cell (15.4%) types. The total DRM was 15.4% (n = 19). The 5 year recurrence-free survival was not significantly different between early-stage high-grade endometrioid versus non-endometrioid endometrial cancer (P = 0.72).
CONCLUSION: Distant recurrence and DRM was high in patients with endometrial cancer regardless of histological type, suggesting the need for different therapies in early-stage high-grade non-endometrioid and endometrioid tumors.
Comparison of two minimally invasive approaches to endometrial cancer staging: a single-surgeon experience.
J Reprod Med. 2015 Mar-Apr; 60(3-4):127-34 [PubMed] Related Publications
STUDY DESIGN: A retrospective review of minimally invasive endometrial cancer staging performed by a single surgeon.
RESULTS: There were no significant differences in operative time, blood loss, surgical complications, or length of hospitalization between laparoscopic (n = 45) and robotic-assisted (n = 77) procedures. On multivariable analysis controlling for surgical chronology, robotic assistance was independently associated with a significantly greater number of lymph nodes (23 vs. 19, p < 0.05; beta 0.163, p < 0.05). When comparing the first chronologic half of robotic-assisted surgeries to the second half, the latter had shorter operative time (208 vs. 246 min, p = 0.01) and a greater number of lymph nodes (27 vs. 19, p = 0.001). Finally, compared to the laparoscopic cases, the second half of robotic-assisted cases had a greater number of total (27 vs. 19, p < 0.001) and pelvic (23 vs. 17, p < 0.001) lymph nodes harvested.
CONCLUSION: There was a learning curve associated with robotic-assisted laparoscopic endometrial cancer staging, with decreased operative time and increased lymph node yield over time. In our study population, robotic assistance was independently associated with a greater lymph node harvest with no increase in operative time or perioperative complications.
Endometrial cancer in a patient with rheumatoid arthritis.
Eur J Gynaecol Oncol. 2015; 36(1):91-3 [PubMed] Related Publications
CASE: The patient, a 60-year-old, postmenopausal Greek woman suffering from rheumatoid arthritis, presented with a complaint of abnormal uterine bleeding. She underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, and pelvic and para-aortic lymphadenectomy. Histopathology revealed endometrial cancer. The final diagnosis was Stage Ib endometrial cancer endometrioid type. She underwent postoperative adjuvant radiotherapy. She remains without evidence of disease, 16 months after initial surgery.
CONCLUSION: Although the present patient was diagnosed at early-stage disease and remains well 16 months after initial surgery, she needs a multidisciplinary treatment approach in order to achieve prolonged survival.
Small cell carcinoma of the ovary of the hypercalcemic type (SCCOHT)--case report.
Eur J Gynaecol Oncol. 2015; 36(1):88-90 [PubMed] Related Publications
Leiomyosarcoma: a rare malignant transformation of a uterine leiomyoma.
Eur J Gynaecol Oncol. 2015; 36(1):84-7 [PubMed] Related Publications
Prevalence of human papillomavirus and the correlation of HPV infection with cervical disease in Weihai, China.
Eur J Gynaecol Oncol. 2015; 36(1):73-7 [PubMed] Related Publications
MATERIALS AND METHODS: A random sample of 9,460 volunteers was simultaneously screened using gene chips and examined by ThinPrep liquid-based cytology test (TCT). Cervical biopsy samples were collected from women with positive HPV-DNA and abnormal TCT for pathological diagnosis.
RESULTS: The overall HPV prevalence was 6.93% (656 of 9,460). A total of 753 subjects were infected with HPV subtypes (including multiple HPV infections). Of those with infections, 688 were infected with high-risk (HR) types (91.37%), and 65 were infected with low-risk subtypes (8.63%). The single-infection rate was 63.1%.The prevalence rates of HPV in women aged 20 to 39 years and 40 to 59 years were 7.29% and 6.71%, respectively. The most common genotype was HPV16. The HR genotypes were associated with cervical diseases such as atypical squamous cells of undetermined significance (ASCUS) (37.9%), atypical squamous cells high grade (ASC-H) (42.5%), low grade squamous intraepithelial lesion (LSIL) (50%), and high grade squamous intraepithelial lesion HSIL (66.7%). Cervical biopsy results show that the HPV detection rate increased in the following biopsy samples: cervical intraepithelial neoplasia (CIN) I (74.11%), CIN II (84.31%), CIN III (90.32%), and squamous-cell carcinoma (SCC) (100%).
CONCLUSIONS: The HPV infection rate with associated cervical disease in Weihai is equal to those in foreign countries but is lower than the average rate in China. The prevalence of HPV was higher in young people. The most common HPV genotype was 16, followed by 52 and 58. HR HPV is the most probable infection factor for cervical diseases.
Epidemiology of ovarian cancer in North Sardinia, Italy, during the period 1992-2010.
Eur J Gynaecol Oncol. 2015; 36(1):69-72 [PubMed] Related Publications
MATERIALS AND METHODS: Data were obtained from the tumor registry of Sassari province which makes part of a wider registry web, coordinated today by the Italian Association for Tumor Registries.
RESULTS: The overall number of ovarian cancer cases registered in the period under investigation was 600. The mean age of the patients was 62 years. The standardized incidence and mortality rates were 11.2/100,000 and 5.1/100,000 respectively. A substantially stable trend in incidence and mortality of ovarian cancer was evidenced. Relative survival at five years from diagnosis was 44.2%.
CONCLUSIONS: The incidence and mortality trends of ovarian cancer in North Sardinia remained relatively stable in the last decades, while prognosis remains relatively poor.
Expressions of survivin, P16(INK4a), COX-2, and Ki-67 in cervical cancer progression reveal the potential clinical application.
Eur J Gynaecol Oncol. 2015; 36(1):62-8 [PubMed] Related Publications
MATERIALS AND METHODS: A retrospective study was performed in 129 cases including 24 squamous carcinoma of the cervix (SCC), 70 cervical intraepithelial neoplasias (CIN), 15 cervical condyloma acuminatum (CCA), ten chronic cervicitis (CC), and ten normal cervix (NC). Protein expressions were evaluated using immunohistochemistry.
RESULTS: Survivin, P16(INK4a); COX-2, and Ki-67 were highly expressed in SCC and CIN compared with others. Their expression rates were gradually increased in CIN I, CIN II, CIN III, and SCC groups, showing 72.00%, 88.00%, 90.00%, and 95.83% for P16(INK4a), 68.00%, 84.00%, 95.00% and 100.00% for COX-2, 76.00%, 96.00%, 100.00%, and 100.00 for Ki-67, respectively. There were significant correlations between survivin and P16(INK4a), COX-2, Ki-67, as well as P16(INK4a) and Ki-67.
CONCLUSION: Survivin, P16(INK4a), COX-2 and Ki-67 play critical roles for development and progression of cervical cancer.
Pyometra in elderly post-menopausal women: a sign of malignity.
Eur J Gynaecol Oncol. 2015; 36(1):59-61 [PubMed] Related Publications
MATERIALS AND METHODS: The authors examined the medical records of 12 patients with pyometra, who were treated between 2009 and 2013.
RESULTS: All patients were post-menopausal, and their mean age was 70.83 ± 6.978 years (min = 61, max = 82). To remove purulent fluid via dilation and because of the probability of malignancy, three patients (25%) underwent cervical biopsy and endometrial curettage; the other nine patients (75%) underwent curettage alone, with suitable antibiotic therapy. Of the 12 patients, nine (75%) had gynecologic malignancy [(endometrial cancer, n = 5, 41.6%), (cervical cancer, n = 3, 25%), (uterine leiomyosarcoma, n = 1, 8.3%)]. In three (25%) patients, the cause of pyometra was benign pathologies, among which the most common were leiomyomas (n = 2, 66.6%).
CONCLUSION: Pyometra diagnosed during the post-menopausal period should be considered a complication caused by gynecological malignancy until proven otherwise.
Combination therapy of liposomal paclitaxel and cisplatin as neoadjuvant chemotherapy in locally advanced cervical cancer.
Eur J Gynaecol Oncol. 2015; 36(1):54-8 [PubMed] Related Publications
MATERIALS AND METHODS: The authors retrospectively reviewed the clinical records of patients with cervical cancer who received NACT with liposomal paclitaxel and cisplatin at Sun Yat-sen University Cancer Center from April 1, 2008 to December 31, 2012. Liposomal paclitaxel and cisplatin was administrated intravenously at a dose of 175 mg/m2 and 75 mg/m2, respectively.
RESULTS: The total response rate was 86.1% (62/72) including a complete response and partial response rate of 27.8% (20/72) and 58.3% (42/72), respectively. Stable disease was observed in 12.5% (9/72) of patients and progressive disease in 1.4% (1/72). Hematological toxicities were the major dose-limiting toxicities. Grade 3/4 neutropenia and anemia developed in 18.1% (13/72) and 6.9% (5/72) of patients, respectively. Peripheral neuropathy occurred in 6.9% (5/72) of patients (all grade 1).
CONCLUSION: The study findings support further evaluation of liposomal paclitaxel with cisplatin as an additional chemotherapy regimen which may be efficacious and tolerable in the NACT of cervical cancer.
Primary peritoneal cancer: study of 14 cases and comparison with epithelial ovarian cancer.
Eur J Gynaecol Oncol. 2015; 36(1):49-53 [PubMed] Related Publications
MATERIALS AND METHODS: The authors retrospectively reviewed data from 14 patients with PPC and 219 patients with EOC treated at the present hospital from January 2005 to December 2012, including demographic data, pathologic findings, treatments, and outcomes.
RESULTS: Patients with PPC were significantly older (62.6 ± 8.4 years) than those with EOC (56.3 ± 11.3 years) (p = 0.045). There was no significant difference in serum CA-125 levels. The five-year survival rates did not differ significantly between patients with PPC (61.1%) and those with EOC (60.3%; p = 0.78); nor between patients with PPC and those with Stage III serous EOC (43.8%; p = 0.40).
CONCLUSIONS: Treatment strategies for EOC applied to PPC apparently led to similar survival patterns among the two patient groups. Cytoreductive surgery combined with pre/postoperative platinum-containing chemotherapy may be effective for PPC patients.
Effect of lentivirus mediated cyclooxygenase-2 gene shorthairpinRNA on invasiveness of endometrial carcinoma.
Eur J Gynaecol Oncol. 2015; 36(1):44-8 [PubMed] Related Publications
MATERIALS AND METHODS: Double-stranded DNA oligonucleotide of COX-2-shRNA was designed and synthesized, and the recombinant lentiviral vector COX-2-ShRNA (LV-COX-2-ShRNA) was constructed. LV-COX-2-ShRNA, pHelper 1, and pHelper 2 were transferred into 293T cells, followed by lentiviral packaging. The virus titer was tested according to expression level of GFP in 293T cells. HEC-1B cells were infected with recombinant lentivirus. The silencing of COX-2 gene was assessed by real-time PCR and western-blot, and the in vivo invasiveness of HEC-1B cells was analyzed by transwell invasion assay.
RESULTS: Recombinant lentiviral vector expressing siRNA targeting COX-2 gene was successfully constructed to harvest the recombinant lentivirus with the concentrated virus suspension titer of 5 x 10(7)Tu/ml. Compared with control group, the inhibitory rate of COX-2 expression in HEC-1B cells in siRNA group were 61.87% and 67.48% at mRNA and protein level, respectively. The mean number of cells penetrating matrigel was 16.6, which was significantly less than the control group 50.2 and non-specific siRNA infection group 47.2, the invasion inhibition rate being 64.8% (p < 0.01).
CONCLUSION: RNA interference can inhibit the invasiveness of HEC-in cells.
The role of mTOR signaling pathway in premalignant and malignant cervical lesions.
Eur J Gynaecol Oncol. 2015; 36(1):36-43 [PubMed] Related Publications
MATERIAL AND METHODS: The study included 38 cases diagnosed as LSIL, 31 cases as HSIL, 29 cases as Ca, and eight control cases from normal cervix. Immunohistochemistry was used to assess the expression of pAkt, p4E-BP1 and pS6.
RESULTS: Statistical analysis revealed significant differences between HSIL and Ca groups compared to controls regarding intensity, positivity, and total scores for all three molecules (p < 0.001). A trend for higher expression with increasing grade of dysplasia was demonstrated.
CONCLUSION: These results strongly support the view that the mTOR signaling pathway is involved in cervical carcinogenesis.
The prognostic significance of pretreatment [18F]FDG-PET/CT imaging in patients with uterine cervical cancer: preliminary results.
Eur J Gynaecol Oncol. 2015; 36(1):30-5 [PubMed] Related Publications
MATERIALS AND METHODS: Patients with cervical cancer in FIGO Stages IB1 to IVB were imaged with PET/CT prior to treatment during one of the staging work-ups. The patients were observed for a median of 31.4 months (range, six to 89 months) after the initial treatment. The standardized uptake value (SUV) max of the primary cervical tumor mass was compared with the prognostic factors. RESULTs: A total of 81 patients who were primarily treated with radical hysterectomy (RH, n = 45) or concurrent chemoradiation (CCRT, n = 36) were analyzed. Multivariate analysis indicated that larger tumor size (> 4 cm, OR 8.694, 95% CI, 1.638-46.146), deep stromal invasion (≥ 1 cm, OR 7.249, 95% CI, 1.141-46.039) by the primary tumor, and pathologically confirmed pelvic lymph node involvement (positive, OR 14.586, 95% CI, 2.072-102.674) were significantly associated with recurrence after treatment. However, pretreatment SUVmax was not a significant independent predictor of disease recurrence (OR 1.058, 95% CI, 0.255-4.398).
CONCLUSION: [18F]Fluorodeoxyglucose (FDG) uptake by the primary tumor showed a significant association with several risk factors that have been identified as treatment predictors. However, a high pretreatment SUVmax was not predictive of recurrence in uter- ine cervical cancer patients.
Laparoscopic ovarian transposition in young women with cervical squamous cell carcinoma treated by primary pelvic irradiation.
Eur J Gynaecol Oncol. 2015; 36(1):25-9 [PubMed] Related Publications
MATERIALS AND METHODS: Twenty-seven premenopausal patients were treated with radiotherapy for a cervical squamous cell carcinoma. Laparoscopic ovarian transposition to paracolic gutters with uterine conservation with pelvic common iliac lymph node and para-aortic lymph node sampling were performed in ten patients at the same time of laparoscopic ovarian transposition. Preservation of ovarian function was assessed by patients' symptoms and serum follicle-stimulating hormone level.
RESULTS: Bilateral or unilateral laparoscopic ovarian transposition was performed in 27 patients: 22 cases Stage IIB, one case Stage IIIA, and four cases Stage IIIB. No immediate intraoperative or postoperative complications were observed. Two of the ten patients were confirmed by lymph node metastases. One patient was lost to follow-up. Ovarian preservation was achieved in 18 (69.2%) of 26 patients. No patient was detected with ovarian metastasis at follow-up.
CONCLUSIONS: Laparoscopic ovarian transposition is a safe and effective procedure for preserving ovarian function. This procedure may be considered in premenopausal women who need to undergo pelvic irradiation for cervical squamous cell carcinoma, especially for those less than 40 years of age. Otherwise, para-aortic lymph node or common iliac lymph nods sampling at the same time of laparoscopic ovarian transposition may preferably guide radiation therapy.


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'Belting out ballads saved my life': Woman, 37, survives collapsed lung because singing made her remaining lung extra strong
- Chez Payne-Annetts had rare condition linked endometriosis which caused womb tissue to develop in her chest causing her right lung collapse
- Her lung collapsed three times before she was finally diagnosed
- Had surgery to remove parts of her lung which were irreparable, clear womb deposits from her chest, and place a wire mesh across diaphragm
- She now has to take strong contraceptives to prevent the condition reoccuring
Chez Payne-Annetts' (pictured) right lung collapsed three times because she has a very rare condition which causes womb tissue to develop in chest
A musician who suffered a collapsed lung was told her life was saved by her love of singing.
Chez Payne-Annetts, 37, struggled to breathe when her right lung repeatedly collapsed because it was penetrated by deposits from her womb.
Surgeons told Mrs Payne-Annetts, who sings in a rock band, that her left lung had become so strong after years of singing that it had made up for the low capacity on her right side.
Mrs Payne-Annetts said: 'I'm a bit like Sam Bailey from X Factor in that big ballads are my speciality. I regularly sang in pubs and clubs with my karaoke equipment, but for a year I had noticed some of the power had dropped off my voice.
'After I had been very poorly for a week, I was sent for a chest X-ray. I had just got home from the appointment when the phone rang and I was asked to go back to hospital urgently.
'My right lung had completely collapsed. The consultant who met me at the hospital said he was amazed I was able to walk into A&E - he expected me to be on the floor.
'A surgeon later said that, because I had been so active with my singing, my other lung had grown very large and had compensated for the lack of capacity.
'In theory, I should have died. When my lung collapsed it should have pushed across the chest cavity, putting pressure on my heart, leading to cardiac arrest.
'It's a very common outcome, which is why collapsed lungs are taken so seriously. But because my other lung was so strong, it didn't happen.'
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Mrs Payne-Annetts was told she probably only survived because singing made her left lung strong enough that it could compensate for her right lung when it collapsed. She is pictured (second from right) with her band
Mrs Payne-Annetts (pictured with her husband, Clint) was only diagnosed after her lung collapsed for a third time in February 2009
Mrs Payne-Annetts was diagnosed with catamenial pneumothorax - a condition closely connected with endometriosis.
The condition occurs when womb tissue develops in the chest.
It is extremely rare and usually occurs within 72 hours of the start of a woman's period.
Catamenial pneumothorax is a rare condition that occurs when womb tissue develops in the chest.
It is closely associated with endometriosis - a common condition in which womb tissue occurs outside of the womb, most commonly on the ovaries and in the pelvis.
It is extremely rare and usually occurs within 72 hours of the start of a woman's period.
It causes air to become trapped in the space surrounding the lungs causing one to collapse.
The exact cause is not understood but some patients suffer numerous lung collapses.
It causes air to become trapped in the space surrounding the lungs causing one to collapse.
The exact cause is not understood but some patients suffer numerous lung collapses.
Mrs Payne-Annetts made repeated trips
to hospital over the winter of 2008 and 2009 before a specialist at
Guy's and St Thomas' Hospital recognised the symptoms.
She was eventually diagnosed in February 2009.
Mrs Payne-Annetts, of Wargrave, Berkshire, said: 'At first it was thought to be pneumonia. It often felt like someone was sat on my chest. I just thought I was eating too much food - too much ice cream, alcohol and too many big meals with my mum.
'After the first lung collapse, they
aspirated my lung and sent me home. But when my lung collapsed for a
second time, it suddenly became very serious.
was due for urgent surgery but after a period of exercise with a chest
drain attached, my lung re-inflated and I was again told I could go
'But then I experienced a familiar feeling - as if popping candy was in my chest - so I went back to hospital.
'A surgeon asked me some seemingly-random questions about my cycle and whether I'd ever been diagnosed with endometriosis.
Mrs Payne-Annetts (pictured singing in a choir) had to have surgery to remove the damaged parts of her lung, to remove womb tissue from her chest and to place a wire mesh over her diaphragm
After her operation, Mrs Payne-Annett had to take six months of work meaning she lost her job and her house
Mrs Payne-Annetts said: 'Today I have three lucky scars (pictured). I was in hospital for seven days and off work for six months. Clint found it hard to see me suffer. I hated putting my family through that stress'
'I was very lucky to have been diagnosed so quickly - I've since spoken to people who have struggled for years before their doctors knew what was going on.'
Five months after she first experienced symptoms Mrs Payne-Annetts had surgery to remove the parts of her right lung which were irreparable, clear the womb deposits from the chest cavity, and place a wire mesh across her diaphragm.
For the following seven months Mrs Payne-Annetts' husband Clint, 33, a local authority Environmental Officer, could only look on as she recovered from the major surgery.
Mrs Payne-Annetts said: 'Today I have three lucky scars. I was in hospital for seven days and off work for six months. Clint found it hard to see me suffer. I hated putting my family through that stress.'
Mrs Payne-Annetts, who runs a business which organises music playgroups for toddlers, now regularly takes high-dose contraceptives to prevent the condition from recurring.
Mrs Payne-Annetts now has to take strong contraceptives to prevent the condition reoccurring
Mrs Payne-Annetts (centre) said: 'I used to mope about my lot in life. But even though we lost a lot that year - I lost my job and we lost our house because I couldn't work - I now realise that life is what you make it'
She said her experiences have spurred her on to continue singing.
She said: 'When I was very ill and low in hospital I wrote out a "bucket list" - one of the items was to sing in a rock band. I've been a member of my band, named Fully Twisted, for more than three years now.
'I used to mope about my lot in life. But even though we lost a lot that year - I lost my job and we lost our house because I couldn't work - I now realise that life is what you make it. We have to make the best of it, and keep trying.
'I'm a lot more carefree. I have a motto now: "Keep Moving Forward". Unexpected things happen, but you've got to keep moving forward.'
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Inspiration for your home | A bathroom with black details - It is not often I look into everyday bathroom details, but after discovering how updating my bathroom with some small black items like i did *here*, can g...
25 January, 2012
New Angel For January ….
Posted by bee bon at 8:25 AM
8 comments:
I like the colours and the originality of this lovely fairy, what a good selection to start the year, this pretty January fair. Well done. Regards Ann SmithReplyDelete
- AnonymousJanuary 25, 2012 at 2:58 PM
I like this.ReplyDelete
Very original, could be used commercially.ReplyDelete
So beautiful Bee! xxxxxxxxReplyDelete
Thank you for the lovely comments on my Angel xxxReplyDelete
Love the new Angel Bee and especially the name. xxReplyDeleteReplies
Hi Erin and Thank you! Do you think i should add Agnus to the card collection?Delete
Such a beautiful angel, Bee!ReplyDelete
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Can not price shop on their website. They want to make you schedule an appointment in order to get prices. I don't have the time to waste on making appointments everywhere just to shop around. FAILLike this review?Yes|Flag Abuse
Meineke Car Care Center
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Great place! I just got new brakes there and they were friendly, knowledgable and affordable. They will be getting all my business!Like this review?Yes|Flag AbuseProvided by Citysearch
I was taking a long trip out of state, I went in to Meineke to have a oil change done before my trip. The guy at the counter walked me to my truck to show me something. I could not believe my eyes when I saw 0ne of my front tires completely bald, and had wires hanging out of the rubber. They advised me to get new tires and for me to have an alignment check. I will be returningLike this review?Yes|Flag AbuseProvided by Citysearch
I needed brakes on my truck, I called every place in town, meineke gave me the best deal. I saved close to $100 dollars with the promotion they were running. I am very happy with the service and the price.Like this review?Yes|Flag AbuseProvided by Citysearch
I got an oil change done for 19.95, the service was good and the people there were very friendly. Although at first I was a little taken back by the suggested repirs that they recommended, I realized that in fact all of the repairs mentioned were necessary. At first I said NO Thanks to their recommended services, a few months went by and I was having some car issues. I went to another shop and they told me the same t... view moreLike this review?Yes|Flag AbuseProvided by Citysearch


text:
Police officers aren't the only people who lie about crimes. That's not the point. The police are supposed to uphold the law. Criminals are supposed be the ones who break it. We should be able to tell the difference between them.
The 40th Annual National Association of Black Journalists Convention and Career Fair will be held August 5th through August 9th in Minneapolis, Minnesota.
Fearing for your life every time you walk outside, every time you get behind the wheel, every time you see a police officer, every time you breathe, is exhausting. Living in a world in which your blackness and woman-ness makes you less than human -- a hypersexual, angry or subservient caricature, the constant target of catcalling, rape and assault -- is exhausting.
In order to truly make our communities safer, we must make sure that people who have served their time are able to fully and productively engage in our society -- whether through education or employment or some other constructive means.
My professor's perception was rooted in a common false meme that has followed black America since slavery -- the idea that we lack financial acumen, don't know how to build businesses, need to be told what to do with our finances, and are overly reliant on government handouts.
Wouldn't it be great to celebrate black people, just for being black? Nothing is more positive than flipping the script. Where there is oppression, we will uplift. And where there is hate, we'll inject love.
"He that is greatest among you shall be your servant." The late Nelson Mandela, former President of South Africa, modeled servant leadership in action. His leadership focused on the importance of community-building and empowering others to lead social change.
During our weekend together, joy sat right next to pain, our celebration of life right next to our grieving of death. I left feeling affirmed and hopeful.
People of color are dying in custody on a regular basis in this country, but the clearest outrage is being directed against a lion dying at the hands of a hunter in Zimbabwe.
America has always relied on black forgiveness to absolve itself of white guilt. The Charleston massacre was no different. By choosing to highlight the forgiveness of the black faith community, they shifted the burden of responsibility onto the oppressed in a classic display of deflection.
The scarring of war and poverty and racism that Malcolm X spoke of continues. It's time that students learn about the long history of activism that has challenged these deadly triplets.
When I visited Christian Love Baptist Church in Irvington, N.J. on July 19 and heard Johnson speak, six years after her son's death, it wasn't a dramatization of events it was real life. A mother poured her heart out to a congregation, which understood her pain.
While access to culturally diverse providers is low, the cost of mental health treatment remains high, which serves as an additional impediment to bridging the gap between the onset of symptoms and accessing professional care.
When I went to South Africa in 2010 to lead a creative writing club for teenage girls, I made sure to emphasize that word: club. I had never taught writing before, didn't have a teaching assistantship as I earned an MFA in nonfiction. I would not be correcting their grammar, nor assigning homework. Besides, how could I persuade girls to spend their Saturday afternoons in a writing class?
I am sorry for having even an ounce of doubt because I did not want the legacy of America's dad being black to deteriorate. I apologize for being so obsessed with that legacy that it blinded me to any wrongdoing.
No one I knew ever trusted the police. We never believed that they were there to protect and serve us. This became abundantly clear when I was 14 years old.
Getting behind the wheel, Bland had three strikes against her. She was black, female and fearless, a combination that is antithetical to all the vaunted white-centered narratives of driving and freedom in the U.S.
While police brutality affects people of all races and backgrounds in the U.S., it's important to note that black citizens face a unique experience within America's criminal justice system, just as they've faced a unique state of affairs for centuries in the United States.
Dear fellow white feminists, we need to talk about Sandra Bland. More specifically, we need to talk about why we aren't talking about Sandra Bland.
Apparently you are still living in 2009, Jamie Foxx, Kanye West,(KEYSHIA COLE November,2010) along with many other celebrities have had the nude pictures leaked. Did they leak their pictures, Kim K is an celebrity that had a sex tape leak, did Ray J leak it. Now this seem like an outdated article seeing young Chris has scored a number one song, " Deuces" that stay on Billboard for nine weeks. He recently as last month had two songs go platinum, Yeah3x It certified platinum in New Zealand by the RIANZ and 3x platinum in Australia by the ARIA. In the United Kingdom and as of In February 2011, "Yeah 3x" had officially sold one million digital copies in the United States. He also has another single " Look At Me Now" featuring Lil Wayne and Busta Rhymes that is just about Gold with over 444,000 copies sold to date. Maybe people are starting to like him for his talent again, because he isn't by far the only celebrity on twitter that has words with others or speak his mind,not with the likes of Charlie Sheen,Ciara, Rihanna, Soujaboy, 50 cent etc. yet every time young Chris say anything that people don't like, he's then crucified. And in closing, he's still doing well on the radio. Let the man live....
Share a website with you ,
( http://www.agiobase.com )
Believe you will love it.
We accept any form of payment
This comment is so well written there should be no other responses. You said it all. Once again very well! When the whole Rhianna -Chris Brown Hype started; I said to myself as a woman who has three daughters the oldest 20,while he was wrong, they have a lot of growing up to do and their lives are just beginning. Never should the incident or actions of these artist take away from their talent.
this is why i dont send pictures of myself naked to any gal. dont care how naughty her pics are.
His package is all good :)
What chu talkin bout? cleo!!!!!! you seen it? Is he packin girl? I wanna see, let me see, LET ME SEE!!!!!!! LOL.
How u do? LOL! You are silly.:-) That pic is unnecessary. Not sayin he isn't attractive but come on? He knew that this pic was going to leak out? This is just another publicity stunt to promote his new album. Have a good day!
Like I said when Chris first dyed his hair "Blonde", he should be himself. Regardless if it was for a video, I am not feelin it. I feel that he was aware of this pic being out there on the web? This is just another publicity stunt for his upcoming album. I guess he wants to touch his fans in a different way? I really miss the Ol Chris?
Oh dear - Is this what it takes now to promote something?? Sad, so sad!
GUUUUURRRL, Where you been, Paris Hilton, Kim Kardashian, Pamela Anderson, And those are just the ones that come to mind right off the top.


text:
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The hotel main atraction is location. Is close to everything we need in Chihuahua…
The hotel was very modern and greatly located! Loved the room accomodations
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text:
Zdeno Chara
In case you missed it: Tim Thomas had another great night
Dec 15, 2011, 1:15 AM EDT
Check out his nifty "Fungo job."
Canucks GM addresses Bolland comments
Dec 14, 2011, 4:46 PM EDT
The Sedins are plenty tough, says Mike Gillis.
NHL Power Rankings: Not ours, someone else's
Dec 13, 2011, 5:02 PM EDT
Rangers on top, and deservedly so.
Chara might not miss three games after all
Dec 12, 2011, 1:35 PM EDT
On his injured left knee: "It feels better than I expected."
Update: Chara to miss three games with leg injury
Dec 11, 2011, 4:33 PM EDT
Still no word on what the injury is, though.
Chara hurt in Bruins win
Dec 11, 2011, 10:42 AM EDT
Hulking blueliner knocked out with an apparent knee injury.
PHT Morning Skate: Will there be changes in Los Angeles?
Dec 11, 2011, 8:30 AM EDT
Will the Kings be forced to make any changes? Will the Minnesota Wild every be satisfied? Does anyone really know how old Chris Chelios is these days? All this and more in today's Morning Skate…
Enforcers card collection: brilliant, bad timing or both?
Dec 9, 2011, 8:18 PM EDT
ITG is set to release a rather controversial card set, which even includes Wade Belak.
Tyler Seguin, Superstar
Nov 30, 2011, 4:10 PM EDT
So says teammate Chris Kelly.
PHT Morning Skate: Coaching hot seat edition
Nov 28, 2011, 7:00 AM EDTComments Off on PHT Morning Skate: Coaching hot seat edition
What coaches aren't on the hot seat by now? There's a few more to look out for now. That and more in the Morning Skate.
Pacioretty faces Shanahan hearing over Letang hit
Nov 27, 2011, 11:42 AM EDT
Montreal forward will meet with NHL discipline czar on Monday.
Kris Letang gets nose broken, scores game-winner
Nov 26, 2011, 10:30 PM EDT
Kris Letang has his "I am a hockey player" moment.
Match-up to watch: Zdeno Chara vs. Johan Franzen
Nov 25, 2011, 10:57 AM EDTComments Off on Match-up to watch: Zdeno Chara vs. Johan Franzen
One key match-up to watch in this afternoon's Thanksgiving Showdown has the Bruins' top defender and the Red Wings' top sniper.
Today on NBC: Red hot Bruins look to keep rolling against hot Wings
Nov 25, 2011, 9:20 AM EDT
It's the first ever Thanksgiving Showdown and this one has a Bruins team looking to make it 11 wins in a row against a Wings team looking for their fourth straight win.
Fight night in Buffalo: Don't poke the bear
Nov 23, 2011, 8:33 PM EDT
The tables were turned on Wednesday night when a Sabre took a run at a member of the Bruins. Needless to say, the Bruins had a stronger response than the Sabres had when Lucic hit Ryan Miller.
All-Star voting has three Sens among top six
Nov 22, 2011, 5:35 PM EDTComments Off on All-Star voting has three Sens among top six
BTW, the All-Star Game is in Ottawa.
No charges for Chara in Pacioretty incident
Nov 17, 2011, 2:10 PM EDT
Prosecution "not reasonably convinced it could establish evidence of guilt."
Are the Bruins villains? If so, should they embrace it?
Nov 15, 2011, 12:26 PM EDT
The Black-and-Gold might as well start wearing the black hats, columnist writes.
Pacioretty gives back to Montreal hospital
Nov 7, 2011, 3:15 PM EDTComments Off on Pacioretty gives back to Montreal hospital
Creates foundation to raise money for a new MRI machine.
Mike Milbury gets the call tonight for a pair of old friends in Isles-Bruins
Nov 7, 2011, 12:04 PM EDT
Mike Milbury gets the call tonight to do color commentary between a pair of teams he knows very well.
Are the big, bad Bruins being targeted by the refs?
Oct 30, 2011, 1:58 PM EDT
Or is Boston's strategy just backfiring now?
Pacioretty faces Chara for the first time tonight
Oct 27, 2011, 12:46 PM EDT
But the Habs and Bruins have bigger worries.
Zdeno Chara might still face criminal charges in Montreal
Oct 26, 2011, 3:08 PM EDT
The hit he laid on Canadiens F Max Pacioretty back in March is still under investigation.
PHT's Morning Skate: Zdeno Chara is your pink nightmare
Oct 26, 2011, 7:00 AM EDT
That's right, it's Zdeno Chara in a pink rabbit costume. Good luck getting that vision out of your head all day.
Should Bruins fans 'thank' Joe Thornton for their Stanley Cup win?
Oct 22, 2011, 3:07 PM EDT
In an abstract and indirect way it helped open up money for the Bruins' rebuild, but for the most part, the answer is "No."
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text:
My husband has been taking Advair and it is very expensive. We need to find a generic for Advair as we are on a very limited income. Thank you bp
Is there a generic for Advair?
- Posted:
- 1 Mar 2010 by missouriboy
Answers (1)
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What is the conversion dose from Advair Diskus 250/50 to the Advair HFA Inhaler?
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text:
Bohally's Kiwi Christmas tale
Relevant offers
A Bohally Intermediate School pupil has performed on stage with some of New Zealand's best-known actors from the small screen.
Caitlyn Woodley was among the group of year 8 pupils who won the ChildFund New Zealand Pens Against Poverty national play-writing competition in August, with their adaptation of the contemporary Kiwi Christmas tale Mary's Christmas Yarn.
The play was performed by professional Kiwi actors Jason Wu, George Henare, Annie Whittle, Laura Hill, Andrew Laing, Rachel Nash and TV One newsreader Peter Williams.
And right up there with them was Caitlyn, as Mary. She got the part after an audition.
Although it involved 12 hours of rehearsals over four days, the experience of meeting, talking, working and performing with professional actors had been "spectacular", Caitlyn said.
"This morning I was so excited I asked my mum if we could go back up to Auckland and do it all again," she said yesterday.
Group members Sammy Jarvis, Morgan Gurr, Emma Gardiner, Chloe Crawford and Grace Williams were among an audience of more than 200 who watched Caitlyn in the show at St Matthew-in-the-City, in Auckland, on Monday night last week.
Seeing the play performed by real actors had been rewarding, Emma said. Morgan hoped their work might lead to Combined Colleges' school productions in Blenheim being written by students.
The pupils were accompanied by family and Bohally Intermediate teacher Rachael Moran. They appeared on TV One's Breakfast and Good Morning shows as well as Nightline on TV3.
A tour of the Shortland Street set, the Mary Poppins musical and visits to the SkyTower and Auckland Zoo were among highlights of the three-day trip, Miss Moran said.
Proceeds from the performance go to ChildFund New Zealand's Christmas Gifts that Grow cause, for gifts to poverty-stricken families in the developing world.
- The Marlborough Express
Sponsored links
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Boundaries set for Marlborough whitebait season
Marlborough Boys' College tells ministry not to rush site decision
Is the region better served by having multiple events over one weekend or spread out throughout the year?Related story: (See story)


text:
Grapevine Firefighters Battle 5-Alarm Blaze
October 12, 2013 9:57 PM
GRAPEVINE (CBSDFW.COM) – A 5-alarm fire started at an apartment complex near Grapevine Mills Mall Saturday night.
It happened at 2311 W. Grapevine Mills Circle at about 8:45 p.m. The apartments are currently under construction. Witnesses reported hearing loud explosions and the blaze can be seen from miles away.
No injuries were reported. This is a developing story. Please stay with CBSDFW.COM and CBS 11 News for updates.
(©2013 CBS Local Media, a division of CBS Radio Inc. All Rights Reserved. This material may not be published, broadcast, rewritten, or redistributed.)
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Dress for (Wedding) Success
Before you go out and enjoy Valentine's evening, check out today's amazing chat on wedding fashion. Julia Lichtman Kepniss and Carin Rosenberg Levine from Hitched in Georgetown tackled everything from veils (they're so expensive—what to do?) to shoes (do they have to be white?) to which designers make short dresses perfect for tearing up the dance floor.
Now a question for you: What kinds of experts do you want to see in future chats? More planners? More fashion pros? E-mail me at firstname.lastname@example.com so I can bring in people who have the advice you're looking for.
Looking for past chat transcripts? Find them here.
To read the latest Bridal Party blog posts, click here.
Posted at 02:25 PM/ET, 02/14/2008 RSS | Print | Permalink | Comments () | Washingtonian.com Blogs
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Bought it for my daughter's first birthday cause she loved it so much at daycarePublished 1 month ago by Ryan
Very disappointed in this Llama book. I bought several Llama books for my toddler because they are fun for me to read. This book has very few words and just felt like a rip off.Published 2 months ago by Amazon Customer
Great book. My son loves it. It was in great condition when it arrived.Published 2 months ago by Joshua P Gossett
Can't get enough reading and waits each day to hear them!!!!Published 3 months ago by Stephen Carden
This is my 14 mo old son's favorite book. He loves the sounds and he brings it to me to read on a daily basis. Read morePublished 4 months ago by Mggc


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A new high-tech unmanned vessel, launched with the help of Google, will use innovative technologies from the boatbuilding and mapping fields to map shorelines and
Bollinger Shipyards has delivered the 14th Fast Response Cutter (FRC), Heriberto Hernandez, to the United States Coast Guard (USCG).
The 154-foot patrol craft
Transas, one of the world's leading providers of integrated navigation solutions, received ECDIS type-approval from the Korean Registry (Korea Marine Equipment Research Institute),
Cranes manufacturer Effer informs its marine crane has recently been installed aboard the U.K. Royal Navy's patrol vessel HMS Mersey.
The new 5s 275M crane,
A Damen RoRo 5612 was launched this month at Halong Shipyard in Vietnam, the shipbuilder announced. The RoRo is one of nine Damen vessels ordered by the Royal
China and Russia will hold joint naval and air defence drills in the Sea of Japan, China said on Thursday, the latest exercises between the two countries which could concern Japan,


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Musika Quick Stats
13 Years
Since We Started
Happy Customers
Cities with Students
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I'm a passionate and experienced musician who has been fortunate to see many aspects of the music world. These include studying classical guitar in a high school conservatory at UNC School of the Arts, collaborating with modern dance companies, and film makers. I'm also a founding member of the alternative rock group Salem Lake which I currently sing and play electric guitar for.
I am a dedicated and loyal educator who loves to teach and motive his students. Music is my love, teaching and educating is my passion. I graduate from Morgan State University with a Bachelors in Music (Trumpet & Voice) and Education. I've had the opportunity to study with Wynton Marsalis and Langston Fitzgerald of the Baltimore Symphony. I enjoyed my time as a performer traveling, but, now dedicated and devote my time to education the youth though and about music.
I am a very enthusiastic individual who loves working with students and sharing my love and passion of music. In 2013, I graduated from the Recording Connections Audio Institute with a Degree in Audio and Recording Engineering. As a musician, audio engineer, consultant, and entreprenuer, I have had the opportunity to work on many platforms across the United States. My experience includes creating successful music and entertainment content within a wide variety of music genres, as well as composing for film, animation and other visual media.
I am a passionate musician. I graduated from the University of West Georgia in 2014 with a percussion performance degree. I have performed with many different groups playing styles such as reggae, rock, punk, jazz, and latin. I have performed for church services, weddings, and operas. Music has been a driving force in my life and I look forward to a long musical life.
I am an experienced music instructor dedicated to the success of my students, striving to impart to them the same passion that I have for music. In 2009, I graduated as valedictorian from Emmanuel College with a degree in Cello Performance and a minor in piano. My studies also focused on music theory, chamber music, and orchestra, as well as string and piano pedagogy. After graduation, I temporarily moved to teach music in a mission school in the Dominican Republic, where I lived for two years and became fluent in Spanish. My family and I now live near Athens, GA, where I continue to teach music and perform with a Chamber Music group for special events.
13 Years
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Happy Customers
Cities with Students
Teachers in Network
Once you've met with your teacher for your risk free trial lesson, continuing with Musika is easy! If you are satisfied with your lesson, all you have to do is register with us to continue! The trial will count as your first lesson if you continue, however, with our Great Match Guarantee™ if for any reason you decide not to continue then the trial is FREE. Go ahead give it a try, you really have nothing to lose.
Don't just take our word for it. We hold the highest possible A+ rating from the nations foremost online reliability source: The BBB. We are proud of this rating and value the message it carries. The BBB has affirmed Musika as a reliable, trustworthy, safe business to work with, and we have the customer feedback to support this. We are continually working to make sure that Musika is a business you can trust.
Background checks available on instructors. Instructor can opt to have a background check on file. You can request to only be connected with teachers that have a check. The choice is yours.
Provided you do not have the space or budget to purchase an acoustic piano, such as an upright or baby grand, then a keyboard is a perfectly acceptable alternative. Keyboards with a weighted hammer action are the best option, as the key touch sensitivity is comparable to that of an acoustic piano. As a rule, more keys are better - at least 61 key pianos are advised. The most popular brands of keyboard are Casio, Roland and Yamaha and can be purchased from most musical instrument retailers. Keyboards offer great convenient due to their price, portability and headphones option.
In home lessons are what 90% of our students request. Not only does this provide a convenient means to study music, but we also notice no difference in the quality of lessons done in home or in studio. They are typically structured the same. The main benefit of in-home lessons is the reduction in travel time to another location, and additionaly the student may be able to focus better in your own home since they are familiar with it. Piano lessons in the home offer a practical choice for your family for learning the skill of playing a musical instrument.
Musika teachers do not adhere to one specific method for all their students. Most teachers will customize their lesson plans to the individual needs and skill level of the student. If you are looking for any specific teaching styles or methods to be used in your lessons, please let us know during the matching process and we can try to assign you to the teacher who will best suit your needs. Generally all lessons will cover topics focused on learning to read music, practice skills, music theory and musicianship, ear training, and rhythm skills.
At Musika, we highly recommend that students looking to learn to play the piano do so with a clear goal in mind. Whether your goal is to learn to play your favourite tunes, reacquaint yourself with the piano, or just to play for fun, our experienced teachers can help you make those goals a reality. Learning, developing and improving technique, co-ordination and theory can actually be quicker during adulthood as the complex thought processes and theory are easier to understand. Adults can also help maintain their fine-motor skills, concentration and listening skills into later life.
Children are recommended to start piano lessons no earlier than age 4 or 5. The attention span and personality of the child are something to consider when thinking of taking lessons. Even if your child has no evident musical inclinations, piano lessons offer a great option for introducing your child to music. During their lessons children will learn how to read music, fundamentals of musicianship and sight reading, music theory techniques, and ear training.


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Hot Links: Paddling Out, Naked Men, and Whole Foods Boycott
Arizona is one of 20 states that allows schools to mete out corporal punishment, most often paddling. Now, an education task force panel is calling for a state ban on paddling in schools. School districts must accept or reject the ban by June 30. School officials say they can't remember the last time -- or in some cases, any time -- corporal punishment has been used in their schools...A man was allegedly dragged naked from his West Valley home last night by three men in a home invasion/kidnapping. Details are sketchy at this point, as the alleged victim is not cooperating with police...Firefighters battled a blaze at a recycling plant in Avondale early this morning. The flames were contained, and no one was injured...The Arizona Department of Public Safety is bracing for cuts if Governor Brewer signs the latest budget proposal. The plan could cut DPS' budget by $10 million. Assistant House Democratic leader Kyrsten Sinema says it would be the largest cut for DPS' budget in history...
Area law enforcement officials announced the arrests of several suspected South Phoenix gang members. Since January, more than 63 suspected gang members have been arrested and charged with crimes ranging from drug trafficking to conspiracy in a project called Operation Tri Dent...Labor Unions have joined the boycott of Whole Foods Market, aimed at protesting Whole Foods CEO John Mackey's criticism of President Obama's health care reform plan. Protestors are also pushing the Bravo cable network to drop Whole Foods as one of its show's sponsors.
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High school roundup: Gateway girls soccer team tops No. 3 Fox Chapel
TribLIVE Sports Videos
Emily Stevens scored on a header off a corner kick in the second half to give Gateway (12-2-1, 10-0-1) a 2-1 Section 3-AAA victory over No. 3-ranked Fox Chapel (14-2, 9-2) on Monday night.
The win also clinched a section title for the Gators.
Fox Chapel struck first with a goal from sophomore Emma Slevin in the 55th minute, but Gateway's Carly Seneca tied the game one minute later.
Norwin 12, Connellsville 0 — Micayla Livingston recorded a hat trick, and Jessica Boydim added two goals for No. 4 Norwin (12-1-2, 10-1) in a Section 1-AAA win.
Franklin Regional 4, Hempfield 0 — Courtney Hanchey scored two goals for Franklin Regional (9-6, 7-4) in a Section 1-AAA victory.
Seneca Valley 3, North Allegheny 1 — Class AAA No. 5 Seneca Valley improved to 14-1 overall and 10-1 in Section 2 with a key victory at North Allegheny (10-4, 6-4).
Pine-Richland 6, North Hills 0 — Lydia Sargent had four goals to lead Pine-Richland (9-5, 5-5) to a Section 2-AAA win.
Canon-McMillan 2, Chartiers Valley 1 — Veronica Rothka scored with nine minutes remaining to give Canon-McMillan (7-5-2, 4-3-2) a Section 5-AAA win.
Laurel Highlands 4, Brashear 1 — In Section 5-AAA, Kaylee Rabatin recorded a hat trick to lead Laurel Highlands (5-8, 2-7).
McKeesport 2, Albert Gallatin 1 — Katie Strohm scored with less than 10 minutes to play to seal a Section 4-AAA win for McKeesport (2-11-1, 1-9-1). Mackenzie Bana recorded six saves.
Derry 3, Uniontown 2 — Senior captain Nichole Klapchar scored twice, and Shauna Wambold added a goal and assist to lead Derry (2-11, 2-8) to victory in Section 1-AA.
Mt. Pleasant 4, Waynesburg 0 — In Section 1-AA, Jordan Toohey scored two goals to lead Mt. Pleasant (8-7, 7-4) to victory.
Yough 6, Greensburg Salem 0 — Mikayla Mance had a hat trick, and Hannah Ponitz (2) and Taylor Hampshire also scored to lead Yough (14-2, 11-0) to a Section 1-AA win. Goalie Kirstin Capenos earned her sixth shutout for the Cougars, who have clinched the section title.
Hopewell 3, Ambridge 0 — Abby Losco scored two goals for Hopewell (10-2-1, 10-0-1) in a Section 3-AA win. Kyra Honeywill recorded two saves.
Quigley Catholic 1, Mohawk 0 — Liz Duer scored the lone goal with 18:40 gone in the second half to lead Quigley Catholic (8-7-1, 7-5-1) to a Section 1-A win. Mia Chis had six saves for her sixth shutout.
South Allegheny 5, Beth-Center 0 — Shannon Wygonik, Amber Brownfield and Melanie Girovski were among the scorers, as No. 4 South Allegheny (13-0, 10-0) clinched the school's first section title in girls soccer in a Section 2-A triumph.
Greensburg Central Catholic 8, Riverview 1 — Frannie Crouse scored three goals and added three assists to lead No. 1 Greensburg Central Catholic (10-1, 10-0) to a Section 4-A win.
Jeannette 3, Geibel 1 — Sydney Pecararo's hat trick keyed a Section 4-A victory for Jeannette (2-10, 2-9).
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Senior Nuclear Security Training Instructor
Duke Energy - North, SC
This job posting is no longer available on Duke Energy. Find similar jobs:Duke Energy jobs
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Duke Energy Carolinas (formerly Duke Power) energizes the Carolinas as well as its parent company's sales. A part of top US power firm...


text: This B+B is walking distance from city centre on nice road. The bed was comfortable, not ensuite but then it was pretty cheap so that's fair enough. Friendly owner Good breakfast. The only downside was that my room was below the bathroom and it was a little noisy whenever anyone flushed the loo! But all in all very good value,... More


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Funeral services for Shirley Taylor Hudson, 77, of Lancaster will be held at 4:00 p.m., Tuesday, June 4, 2013, at Baker Funeral Home, Kershaw. Burial will follow in the Forest Lawn Memorial Park, Camden. The Rev. Stephen Owens and Ben Moorefield will officiate.
Funeral services celebrating the life of Esther Rabon Faulk, 80, of Camden, SC will be held at 11:30 AM, on Tuesday, June 4, 2013 at Kornegay Funeral Home, Camden Chapel. Rev. Brian Ogburn will officiate. Burial will follow in Fort Jackson National Cemetery, Columbia, SC. The family will receive friends from 6:00 -7:30 PM on Monday, June 3, 2013 at Kornegay Funeral Home, Camden Chapel. In lieu of flowers, memorials may be made in Mrs. Faulk's memory to Kershaw Health Hospice, 124 Battleship Road, Camden, SC 29020 or the Springvale Baptist Church Cemetery Fund, P.O ...
Tealie (Buddy) Edwards, Jr., 92, of Ridgeway entered into eternal rest on Saturday, June 1, 2013. He was born January 8, 1921 in Warrenton, North Carolina to the late Tealie Edwards, Sr. and the late Rosa Epps Edwards. He is survived by his wife, Bessie Long Edwards, daughter and granddaughter, Yolanda and Iyona Long of Ridgeway and one sister, Lucy Branch of Warrenton, NC.
Mrs. Daisy Mae Cornish, 91, of 3771 Bethune Road, Bethune, SC, passed on Friday May 31, 2013.
Mrs. Edna Saxton, 71, of 1123 Hwy 1 North, Camden, C, passed on Wednesday, May 29, 2013. Funeral arrangements are incomplete and will be announced at a later date by Haile's Funeral Home.
A memorial service for Charles William Sims, 73, will be held Friday at 11:00 a.m. at Powers Funeral Home. The family will receive friends one hour prior to the service at the funeral home. In lieu of flowers, memorials may be made to the Walter M. Crowe Animal Shelter, 460 Fair Street, Camden, S.C. 29020.
Funeral service for Cynthia Ann Dabney-Baker, 53, will be held Sunday at 4:00 p.m. at Powers Funeral Home with burial to follow in Kershaw City Cemetery. The Rev. Scott Lewellen will officiate. The family will receive friends Saturday 6-8 p.m. at Powers Funeral Home. Memorials may be made to the Walter M. Crowe Animal Shelter, 460 Fair Street, Camden, S.C. 29020.
A celebration of life service for Robert Wayne Bertram, 46, will be held Saturday at 3:00 p.m. at Trinity Baptist Church. The Rev. Dr. Chuck Everett will officiate. The Family will receive friends Friday from 6 – 8 p.m. at Powers Funeral Home.
Funeral services for Eleanor Baker "Snookie" Watkins, 76, of Bethune will be held at 3:00 p.m. Saturday, June 1, 2013, at Timrod Baptist Church, Bethune. Burial will follow in the church cemetery. The Revs. Jackie Knight and Jim Wallace will officiate.
A service to celebrate the life of Richard James Rochester, 85, will be held Sunday, June 2, 2013 at 2:00 p.m. at Grace Episcopal Church. The Rev. Phillip Whitehead will officiate. The family will receive friends Saturday, June 1, 2013 from 5-7 p.m. at Powers Funeral Home. In lieu of flowers, memorials may be made to the Riverbanks Zoo and Garden or Grace Episcopal Church.
Funeral service for Brenda H. Webb, 61, will be held Thursday at 3:00 p.m. at House of Prayer with Open Arms Church with burial to follow in Boonetown Cemetery. The family will receive friends Wednesday 6-8 p.m. at Powers Funeral Home.
Mr. Johnny Eugene Stover, Sr., 69, of Camden, entered into eternal rest on Saturday, May 18, 2013. Born in Camden, he was the son of the late J.D. and Margaret Jackson Stover and father of Jacques Stover and Johnny Eugene Stover, Jr. A Celebration of Life Services will be held at 1 p.m. Friday, at Union Baptist Church, Rembert, with burial in church cemetery. Mr. Stover will be placed in the church at 12 p.m. for viewing. Brown's Funeral Home, Camden, is serving the Stover family
Moses T. Nelson passed away on May 21, 2013.
Mr. Ernie Mills, 67, of 30 Black River Road, Camden, SC, passed on Friday, May 17, 2013.
Page 87 of 208
Funeral service for Mrs. Maebell Brevard, 73, of Hempstead, New York, formerly of Camden, will be held Saturday, July 25, 2015, 11 a.m. at ...
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Find your wings with us!
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Newbie? AviaStock.com is a dynamic database which aim is to promote aircraft and parts trading on the web. If you are a : • Seller: create your account, add your aircraft, spare parts, avionics or accessories to our database and hit eventual buyers around the world as well as in your neighborhood. All this is currently free then why to go without doing it ? • Buyer: take a glance through our database. If you don't find what you are looking for, two alternatives are available: you can create a "Wanted" add or activate Avialert, automatic notification by e-mail. You can also use our RFQ form. Plane for sale, microlight for sale, helicopter for sale, aircraft sale. • Dealer: by joining AviaStock.com you will get your own dynamic web page describing your offer, that you can update 24 hours a day. Dealers list. Part dealer, subscribe to our RFQ program. • Other aeronautics actor: flying club, maintenance center, manufacturer, etc., add your company to our aviation dedicated links directory.
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Fri, Jul 31,2015 11:38:09PM EST
Also: Cicare 8, Switchblade Update, Beringer Alaskan Bush Gear, Jack Pelton Interview - Final E-I-C Note: Regularly Daily Airborne Unlimited Programming will resume this Monday now that we're (mostly) recovered from OSH15!!! United States Senator James Inhofe is a regular visitor to Oshkosh for AirVenture, but this year he's a man on a mission, as he explained to ANN. NextGen GA Fund Boss, Michael Dyment reports that the GA community seems to finally be taking the pending ADS-B 2020 mandate seriously. In conversation with ANN, Dyment reported that the firm positions taken by FAA Administrator Michael Huerta and other factors are driving the change in attitude. Kitfox has developed a STOL wing for their popular kits. Kitfox president and CEO John McBean told ANN that development of the new wing was largely customer-driven. It's not all about fixed-wing airplanes at AirVenture. And another market-driven development … this time in the rotary-wing arena is the Cicaré 8, which is a follow-on to the company's T-7 single-place helicopter. Cicare President and Chief Commercial Officer Raul Oreste talked with ANN's Jim Campbell. All this -- and MORE in today's episode of Airborne!!!
Fri, Jul 31,2015 02:43:37PM EST
The BD-5 Web Site The official home of the BD-5 network, the purpose of this web site is to provide information about the Bede Aircraft BD-5, an experimental, homebuilt, single-seat high performance aircraft that first flew more than 30 years ago and which to this day continues to draw crowds wherever one lands.
Fri, Jul 31,2015 02:42:39PM EST
A notice containing information (not known sufficiently in advance to publicize by other means) concerning the establishment, condition, or change in any component (facility, service, or procedure of, or hazard in the National Airspace System) the timely knowledge of which is essential to personnel concerned with flight operations.
Fri, Jul 31,2015 02:41:32PM EST
"The fairing separation is one of our very first critical events. If it doesn't work as planned, it's probable the mission cannot continue."Source: Mike Hawes, Lockheed Martin Orion vice president and program manager.
Fri, Jul 31,2015 02:39:02PM EST
Say Hello To Aero-Twitter! Twitter is designed to work on a mobile phone as well as on a computer (and can be accessed via your IM clients). All Twitter messages (called "Tweets", naturally) are limited to 140 characters, so each message can be sent as a single SMS alert. Brevity is a virtue when using Twitter, since you can't say much in 140 characters (then again, the world would probably be a better place if people spent less time reading their cell-phones, anyway).
Fri, Jul 31,2015 02:38:51PM EST
Company To Serve As Official Airline Of TMCF Programs The Thurgood Marshall College Fund (TMCF) has expanded its partnership with United Airlines; and, that the company will be the "official airline"of the organization's programs during 2015, including its award-winning 2015 Leadership Institute.
Fri, Jul 31,2015 02:37:44PM EST
Westby Middle School Educator Mary Beth Marx Helps Her Students Spread Their Wings Those of us in aviation commonly ponder the issue of piquing the interest of young people in the joy, excitement, and gratification of being involved with aviation. Sometimes it seems like we're beating our head against the wall, but here's a story of a middle school educator stepping out to share her passion for aviation.
Fri, Jul 31,2015 02:35:51PM EST
Allows Installation In Multiple Types Of Airbus Helicopters Maxcraft Avionics Ltd announced today that it has been awarded an FAA Approved Model List (AML) Supplemental Type Certificate (STC) for installation of the Garmin G500H Flight Display System in a series of Airbus (Eurocopter) light helicopters.
Fri, Jul 31,2015 02:32:31PM EST
Joe Trustey Was COO Of Summit Partners Business Executive Joe Trustey and his daughter Anna were fatally injured Wednesday night in an accident at Timmerman Airport in Milwaukee, WI.
Fri, Jul 31,2015 02:29:27PM EST
Citizens For Quiet Skies Lose Court Case Against Mile-Hi Skydiving Colorado Judge Judith LaBuda has found in favor of Mile-Hi Skydiving in a case brought by a citizens group complaining about noise from the company's airplanes.
Fri, Jul 31,2015 02:26:04PM EST
Data From First Test Flight Makes Technology Safer, Lighter And More Reliable Testing of design changes made to the NASA Orion spacecraft's fairing separation system have been completed by Lockheed Martin engineers. These changes resulted from data collected during Orion's first test flight on Dec. 5, 2014.
Fri, Jul 31,2015 02:24:32PM EST
Full-Scale Version Of Aquila UAV Has Been Completed Facebook has completed a full-scale version of the UAV it hopes will allow the company to provide internet access to underserved populations worldwide.
Fri, Jul 31,2015 02:21:43PM EST
Beverly Scott Resigned As MBTA General Manager In February The former head of the Massachusetts Bay Transportation Authority has been nominated by President Obama for a position on the NTSB.
Thu, Jul 30,2015 04:23:19PM EST
Precision Targeting, Or Just Blind Luck? FMI: www.klydemorris.com
Thu, Jul 30,2015 04:22:22PM EST
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Buy Us Some Cracker Jack
For baseball fanatics, it feels like forever since the Yanks swiped their 27th World Series title, this time from the Phillies. But opening day has once again dawned on Americas favorite pastime, so off youll go to Mondays 7:10 p.m. Marlins versus Padres ball game, where youll sit in the crowd. Youll buy yourselves peanuts and Cracker Jack while you root on your favorite Fish. But youll want to come back to Sun Life Stadium (2269 Dan Marino Blvd., Miami Gardens) because Hanley Ramirez and the rest of the Florida Marlins will face the Padres up until Wednesday. Tickets start at $9. Visit florida.marlins.mlb.com.
Mon., April 26, 7:10 p.m., 2010
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