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The USPO recently granted two more patents to Sarepta:
1.Oligonucleotide analogues targeting human LMNA. This patent is intended to cure Hutchinson-Gilford progeria syndrome (HGPS), a rare genetic disease that causes young children to prematurely and rapidly age; and
2. Antisense modulation of nuclear hormone receptors. This patent is intended to treat inflammatory diseases without the usual, and sometimes serious side effects like diabetes, osteoporosis and glaucoma caused by glucocorticoids, the current standard of care.
Sr. Director of Trade, Distribution, Contracting and Managed Markets - The individual will be asked to build and execute the global access and reimbursement strategy for our lead candidate, Eteplirsen, along with our DMD portfolio. And:
Medical Science Liaison - Northeast
Medical Science Liaison - Southeast
Medical Science Liaison - Northwest
Medical Science Liaison - Southwest
The newly created Medical Science Liaison (MSL) position will be one of the first field based members of the Medical Affairs team at Sarepta and will play a pivotal role on the development and commercialization of Eteplirsen as well as support for the Sarepta pipeline.
New Positions posted this week:
Director, Reimbursement and Managed Markets Strategy - This individual will be responsible for building and executing the US reimbursement and managed markets strategy for our lead candidate, Eteplirsen, along with our DMD portfolio.
Director, Specialty Distribution & Patient Access - This individual will be responsible for designing, implementing and managing the day-to-day operations of Sarepta's Specialty Distribution and Patient Access programs for our lead product, Eteplirsen. Additionally, this person will be responsible for driving new initiatives post-launch to ensure these programs continue to provide best-in-class support and minimizing reimbursement as a barrier in order to enhance overall patient access to therapy.
Boys aged 4-6 amenable to skipping exon 51with eteplirsen are now being recruited in Los Angeles and Iowa City.
Among other items in the bill, The Council for 21st Century Cures is established to accelerate the discovery, development, and delivery of innovative cures, treatments, and preventive measures. The priority review voucher program for rare pediatric diseases is revised and extended.
And of important significance to the approval of eteplirsen, this bill amends the Federal Food, Drug, and Cosmetic Act to revise the drug approval process, including by: (1) allowing patient experience data to be considered in the risk-benefit assessment of a new drug. HR6. On to the Senate and the President!
Posted Today by the USPO. Wilton, et al are the inventors, though Sarepta and Murdoch University (in Washington State) are the joint applicants.
Pompe Disease is caused by a missing enzyme that would normally break down glycogen (a sugar). When glycogen is not broken down, it accumulates in the heart, liver, nervous system and muscles, eventually causing respiratory failure and death. Sarepta's drug would splice RNA (exon 2) that contains the coding needed to produce the enzyme that will break down the glycogen. Sarepta's work in the Pompe disease area has been highlighted in its recent presentations, though it is not specifically listed as a development program on Sarepta's Pipeline webpage. Expect it soon.
A kickback is used by a drug company to reward a doctor for prescribing a particular pharmaceutical to a patient. The more informed a patient is about drug alternatives, the less successful a doctor is going to be in prescribing the drug and getting a kickback. The DMD community is the most informed group of parents (and kids) about a complex illness and its alternative treatments that I have witnessed. They are the least likely to be fooled by a doctor intentionally steering them towards the wrong drug to make an extra buck.
Putative treatment for DMD took a few steps back today when the National Health Science of England (England's socialized medical care) once again postponed funding treatment for boys. Boys in other parts of Europe are getting treatment. I hope eteplirsen doesn't slam into that same brick wall in America with its private health insurance companies (or Medicaid for that matter). Action Duchenne leaders said of the government decision makers: "it's cowardice" and "a decision that is symptomatic of poor and unfocused leadership of the health services". No mincing words across the lake by duchenne community leaders.
I like your thinking, thigrlsrk - boys too healthy (scored too high on the 6MWT) to qualify for eteplirsen at the start of trial, and now can't walk at all. Thirty seconds of testimony from a couple of boys like that, along with testimony from a couple of boys who have thrived on eteplirsen, will demonstrate, in real life, what all the numbers and charts and words in the NDA really mean.
is scheduled to complete in April 2016. Enrolling 67-72 children, ages 5 and up for 48 weeks at 13 sites in the US and Canada. All but 5 sites are actively enrolling. Efficacy is not a primary endpoint - only safety (incidents of adverse events), especially heart and lung, but also including lab tests studying hematology, biochemistry, and urinalysis parameters. Secondary outcome measurements for efficacy. Offering intermittent dosing of 6mg/kg for those kids that can't tolerate continuous dosing. No minimum duration, as the company probably expects children to drop out because of adverse events. Clinical trial dot gov website last updated March 5, 2015.
I recall that CG said he was not applying for a breakthrough designation for eteplirsen. Not sure why he chose not to apply. The FDA has already "green lighted" eteplirsen by giving Sarepta a go ahead and submit signal. Once Sarepta completes its rolling submission (by mid year), then the FDA will consider whether the submission will be filed as a new drug application. Probably about the same time, assuming a filing is granted, the FDA will likely schedule an ADCOM review of the data and hear from experts, parents, company officials and, hopefully, kids taking eteplirsen. My limited understanding of the process is that it will take about 6 months from time of "filing" until approval (or denial) under priority review. Speaking of priority review, Sarepta should receive a priority review voucher for eteplirsen if the drug is approved ahead of drisapersin (assuming Sarepta included a voucher request in its NDA submission).
Correction: Murdoch, WA (where Murdoch University is located) is not in Washington state. WA is Western Australia (which makes more sense if Wilton is an inventor).
My guess is that Sarepta will make a huge effort to garner proxies from those millions of shares that were not voted at the shareholder's meeting.
The British government essentially blocked treatment of DMD boys using the approved DMD drug, ataluren.
From the New England Journal of Medicine: After only 12 weeks of PRO051, "new dystrophin
expression was observed between approximately 60% and 100% of muscle fibers in
10 of the 12 patients, as measured on post-treatment biopsy, which increased in a
dose-dependent manner to up to 15.6% of the expression in healthy muscle. After the
12-week extension phase, there was a mean (±SD) improvement of 35.2±28.7 m (from the baseline of 384±121 m) on the 6-minute walk test."
This new trial, treating both exons 45 and 53, is labeled as a Phase 3 trial. There will be 99 enrollees: 33 needing exon 45 skipped, 33 needing exon 53 skipped, and then 33 amenable to exon 45 or 53 skipping but receiving placebos (I wonder why not against natural history like our other trials). Duration, 48 weeks. Trial site locations not yet listed.
Bionerd, any safety/adverse events reports on GS/PPMO? Is this a drug that will require lifetime treatment like eteplirsen? Thanks.


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Tuesday, November 20, 2012
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Yesterday was a long day in the car but I still managed to make a meatless Monday dinner. Originally DH was just going to grab something but I had a few minutes to throw something in the crockpot in the afternoon before I left for my PT appoint... Read more
Sunday, November 18, 2012
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I made this as my new recipe last week. It was pretty good. I didn't have green peppers on hand so I just doubled the red pepper. I found it already in the Sparkrecipe data base and they had used all red peppers as well. The only change that I... Read more
Friday, November 16, 2012
3 comments
Some reason I am dragging this morning. Not sure what it is. It could be the lower calories of yesterday. Scale was down to 249.8 this morning. I've got 9.8 lbs to go before I can really celebrate. I have been trying to get to 240 for over 3 y... Read more
Thursday, November 15, 2012
4 comments
So I have been doing some thinking after my bummer of a weighin yesterday. I decided to go back to weighing daily at least for the rest of this month to see if it helps keep me focused on tracking. I know that sometimes that number isn't going... Read more
Wednesday, November 14, 2012
6 comments
Yesterday was an off day. I did get some fitness minutes logged.
Weighin today... eh, 251.5. Up almost 2 full pounds. That's what not sticking to my carb goal does to me. I really hate tracking but proof is in the scale, I have to do i... Read more
Tuesday, November 13, 2012
3 comments
Halfway successful day yesterday. Not sure what was wrong with me but I sure wasn't right. Screwed up and stopped at a drivethru on the way home. Should have just kept moving but it was calling my name. Over in calories and carbs for the day ... Read more
Monday, November 12, 2012
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Oh boy, what a weekend. I think I am recovered. I haven't tracked food since Thursday but I think I did alright. I made a point to eat freggies whenever possible. I only logged about half of my movement but I'm okay with that. It was too co... Read more
Friday, November 09, 2012
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Heading out of town in a bit to help my MIL get ready to move. It is going to be an emotional day for my MIL and my husband. I hope that I can help keep the peace and provide some comfort.
Read more
Thursday, November 08, 2012
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Just a tracking blog
11/08/2012 Today I am Thankful for: Sparkpeople and all the tools available for this long journey
Today I had less than 200g carbs: didn't track
Today I moved for: 12 minutes... Read more
Thursday, November 08, 2012
4 comments
Not going to focus on yesterday's failures. The day is over and on to a new one.
Right now I have a spoiled cat curled up next to me and that is my morning joy.
Goals for today:
Read more
Wednesday, November 07, 2012
9 comments
Well, down to 249.7 today. Hopefully this will provide the motivation I need to keep tracking.
Goals for today:
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Tuesday, November 06, 2012
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Happy Election Day! Thank goodness for those of us in the USA, this circus should finally be over tonight. I pray that this is not a close election with weeks of recounts.
Goals for Today:
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Monday, November 05, 2012
7 comments
It was a bit of a weird weekend. It is going to be a stressful weekend next weekend so this week I want to feed myself and my husband well so that if we get caught up in some stress eating we will be okay. We were at a birthday dinner over the... Read more
Saturday, November 03, 2012
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Today's weighin had mixed results. I didn't change my ticker because again I couldn't get the same weight 3 times. Guess since it is fall back day the batteries in the scale are getting refreshed as well.
Read more
Friday, November 02, 2012
3 comments
October Goals were:
Increase yearly fitness minutes to 2700. (530 minutes for the month) Read more


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text: Folkestone Camping and Caravanning Club Site (144 reviews) from £7.70 to £12.95 Per person/night Contact Us Book It Images Video Map Select Section Overview Top site for beaches Cliff-top site popular with birdwatchers, sea anglers and Channel hoppers. Our Folkestone Club campsite is ideally located whether you're holidaying in Kent or taking a day trip to France by Channel Tunnel. The campsite enjoys a dramatic cliff-top position with stunning views of the sea and the chalky cliffs of the Dover-Folkestone Heritage Coast. The campsite is surrounded by the trees and shrubbery of The Warren, a local Nature Reserve and a Site of Special Scientific Interest. Nature trails weave their way through The Warren, an important habitat for many rare plants and animals. Guided walks run from April through until September. This peaceful campsite is well laid out with a mix of grass and hardstand pitches. The excellent facilities include a parent and child room with a baby bath, shower, and a highchair with harness. Walkers and dog owners will enjoy the walks from the campsite along the cliffs and beach. You can walk into Folkestone and Dover using the footpath from the site too. Folkestone has a cobbled High Street, harbour, promenade and a sandy beach next to the harbour. Dover, with its world-famous white cliffs, has an interesting castle. South of the campsite is the seaside resort of Hythe, while Romney Marsh boasts three of the finest family-friendly sandy beaches in Kent – Dymchurch, Greatstone, and St Mary's Bay. The shingle beach at Dungeness is backed by an RSPB Nature Reserve visitor centre and the area is brimming with plant and wild life. Access and SatNav Advice Please note that this site is not suitable if you need to leave for an early ferry, as the site gate does not open until 7am, and there is no parking outside the site. No touring caravans on this site. Long narrow access road to site. Worth Noting Sea Fishing from beach. The site overlooks a great shingle beach – the kids will love it. The site is the ideal location for bird watching and walking. WiFi 100% coverage cannot be guaranteed due to rural location, weather conditions and changing flora. These can cause variable signal strength. Hotspots are available. Prices. Eat Local There are several stalls selling fresh fish in Folkestone. Hythe has good greengrocer shops and fishmongers, all selling local produce. A Farmers' Market is held at Capel-le-Ferne. Facilities Folkestone has the following facilities on or around the site. No caravans allowed Members' and non-members' trailer tents welcome Hardstanding with electric hook-up Difficult access/approach Flushing toilet Washbasins Dedicated accessible facilities Chemical toilet disposal point Motorhome stop-off Dishwashing facilities Gas cylinders Pets welcome Coastal Grass only pitch for larger tents Grass pitch with electric hook-up for larger tents Members' and non-members' motorhomes welcome Members' and non-members' tents welcome Grass pitch with electric hook-up Grass only pitch (no electric) Showers Electric shaver sockets Family shower room Drinking water taps Washing Machines Ice pack freezing Payphone Electric hook-up Club Site Wi-fi Sea/loch view Reviews Review 1 |2 |36 |Next » Expand review Recommended: yes 5 Not a place to stay for an extended period of time unless the weather is exceptionally good... Me (Club Member) stayed Jul 2015 This review is for Folkestone Not a place to stay for an extended period of time unless the weather is exceptionally good and you like sitting in the sun. Five days was ample. The walks around the warren made easier once the paths had been cleared. Towing: Difficult Location: Coastal Suitable For: Older couples,Peaceful break Friendliness: 5 Cleanliness: 5 Facilities: 5 Expand review Recommended: yes 5 my wife and I have been members for only nine years, since our first year the warren became... Jeff Golding (Club Member) stayed Jul 2015 This review is for Folkestone my wife and I have been members for only nine years, since our first year the warren became our very favourite site, stunning position and well managed, until Chris Lovell became manager. In my opinion he was the most bombastic, dictatorial, jobsworth whom it has ever been my misfortune to encounter anywhere. His management style totally ruined this site for me and many other members, and I personally know of four couples who resigned their club membership because of his actions. I am overjoyed to say I have just spent most enjoyable 15 nights at the warren, the managers this year are brilliant, as we as members expect our site managers to be. The site was spotless, the welcome was extremely friendly and the whole management team couldn't do enough to make everyone's stay as perfect as possible, but most of all the camp has regained its friendly welcoming atmosphere, thank you Mark, Natalie, Melvyn and Lynda. And just for Mr Lovells information, just because we were allowed to park our units in whichever direction we want, we did not have our pitches measured out to the inch with your tape measure, we were not banned from using the decking areas between 2100 hrs and 0800 hrs and have to tolerate you removing the site dustbins thus forcing the elderly and disabled to carry their refuse the entire length of the site,I am pleased to say that the Warren has NOT fallen into a state of anarchy and lawlessness. Thanks again to the present team for giving us back our special site. Location: Coastal Suitable For: Families,Older couples,Peaceful break Friendliness: 5 Cleanliness: 5 Facilities: 5 Expand review Recommended: yes 5 As above. David Wolfe (Club Member) stayed Jul 2015 This review is for Folkestone As above. Location: Coastal Suitable For: Older couples,Peaceful break Friendliness: 5 Cleanliness: 5 Facilities: 5 Expand review Recommended: yes 5 Despite only booking one night for a tent with no extras, I was given a wonderful welcome as... Alex Welsh (Club Visitor) stayed Jun 2015 This review is for Folkestone Despite only booking one night for a tent with no extras, I was given a wonderful welcome as thought I had booked my entire summer at the site. I found the facilities excellent and very clean. I was also helped in ordering a delivered take-away from a wonderful Nepalese restaurant, I believe run by ex-Gurkhas. The food was incredible. The sea was just a stones-throw away and the views were magnificent. I can highly recommend this site. Location: Coastal Suitable For: Families,Older couples,Peaceful break,Younger couples Friendliness: 5 Cleanliness: 5 Facilities: 5 1 |2 |36 |Next » Travel Local Travel Nearest bus stop: 0.5 miles from site entrance Nearest train station: Folkestone – 4 miles Get Directions to Folkestone Staying here? Public transport near the site Bike ride? Find cycle routes nearby Sat Nav Download our POI file Safe Directions Print Friendly PDF Widget by Frixo Standard Fees For more information take a look at Pricing explained. Minimum booking periods do apply.


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The Liberty County Board of Commissioners heard an hour-long presentation Tuesday evening by Glenda Roberts, chief assessor with the Liberty County Board of Assessors. The board decided not to make any decision on her request to contract with a commercial tax-assessor company.
The Liberty Transit System will begin operating under the first level of modified services beginning Nov. 16, according to Rachel Hatcher, planning director for the Liberty Consolidated Planning Commission.
Ludowici residents will have to wait for a decision on when an election will be held to fill City Council vacancies.
U.S. Rep. Jack Kingston, R-Ga., awaited election results Tuesday night in Savannah's Mulberry Inn, and he was pleased as staffers colored his territory red on a map that tracked congressional winners.
Incumbent Craig Nobles defeated challenger Darrell Ballance on Tuesday to take the sheriff's race in Long County.
The Coastal Georgia Area Community Action Authority will assist eligible households with heating bills.
Republican presidential hopeful Mitt Romney may have scored Georgia's electoral votes Tuesday, but incumbent President Barack Obama took the nation and historically blue Liberty County.
Liberty County overwhelmingly backed President Barack Obama's bid for re-election, voting 65 percent for the Democrat.
Craig Nobles: 2,580 votes (68.47 percent)
The Liberty County Board of Commissioners will have a different dynamic come January, but only one new face will enter the fold.
ATLANTA - Republican Rep. Jack Kingston of Savannah defeated his Democratic challenger Tuesday to win the U.S. House of Representatives 1st District race and an 11th term in Congress.
Click here to view statewide election results as they are compiled at the Georgia Secretary of State's office.
The Hinesville City Council heard and approved 10 action items during Thursday's meeting, including a bond-resolution request by Chief Financial Officer Kim Ryon as well as zoning-and-development plan requests by Rachel Hatcher of the Liberty Consolidated Planning Commission.
A request to force Ludowici to have municipal elections goes before a Long County Superior Court judge Wednesday.
Long County Board of Education candidate Julie Dawson submitted papers last week challenging the decision of the U.S. District Court for the Southern District of Georgia regarding Long County's new district map. According to Dawson, the new map has an error that places her legal residence in District 3. She said it's in District 5.
The Long County Board of Commissioners still is looking over applicants for the full-time Long County fire chief job to replace former Chief Richard Truman ...
The trial stemming from a wrongful-death lawsuit on behalf of former Liberty Regional Medical Center chief operating room nurse Barbara Porter continues in Liberty County ...
An environmental-law firm has filed a "motion to intervene" in a lawsuit filed by Texas energy company Kinder Morgan, which is seeking to build a ...
Long County schools opened their doors Friday to begin the 2015-16 calendar year.
ST. SIMONS ISLAND - Weekend alcohol sales and building a conference center were among the topics discussed Friday during Hinesville City Council's retreat.
Exactly four years to the day after she was admitted to Liberty Regional Medical Center, a civil trial stemming from a wrongful-death lawsuit on behalf ...
Shoppers will get a break from road construction this weekend to go along with the state's suspension of the sales tax for school supplies ...
ST. SIMONS ISLAND - Staggering Hinesville City Council elections and annexing Fort Stewart's cantonment area were among the topics discussed Thursday during a council retreat.
Hinesville is about to get another traffic light.
Four years after she was admitted to Liberty Regional Medical Center, a wrongful death suit for former LRMC chief operating room nurse Barbara Porter started ...
Liberty County will host its first virtual town-hall meeting from 10-11 a.m. Tuesday.
Dr. Yvette Keel became the newest Liberty County Board of Education member after she was sworn in Tuesday morning.
SAVANNAH ― The Georgia Association of Chiefs of Police has named Hinesville Police Chief George Stagmeier as the recipient of the GACP Meritorious Service Award.
Roads – dirt and paved – were the focus during the Liberty County Board of Commissioners' called meeting Monday evening to discuss how to resurrect the Special ...
The Liberty County Hospital Authority board will enter into a lease agreement with Verizon for a cellphone tower to be placed on top of Liberty ...
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On Monday, U.S. Senator Charles E. Schumer made a direct appeal to the New York Metropolitan Transportation Authority (MTA) asking the agency to kick start plans to bring free wireless Internet to the entire Long Island Rail Road LIRR) system, including all trains, platforms and stations. Plans to bring wireless internet to the LIRR have been in the works for months but the MTA has still not acted.
Schumer said the technology to wire the system is readily available and asked the MTA to fast track the pilot projects and the Request for Proposal and approval process saying that if the MTA acts fast, the project may be eligible for federal funding passed as part of the American Recovery and Reinvestment Act (ARRA).
"The time for high speed Internet on rapid transit is right now. It is long past time to bring the LIRR in to the 21st century and wireless Internet will make commuting more productive and pleasant for LIRR riders. The technology is ready and raring to go so its time for the MTA to get rolling," Schumer said.
Several Internet and media providers have expressed interest in providing wireless Internet service on the LIRR. While the typical procurement process could take months or even years to complete, Schumer asked Interim MTA Executive Director Helena Williams to fast track its approval and consider a implementing a pilot program that could be up and running before the end of the year, adding that there are significant customer benefits of adding wireless Internet service to LIRR trains.
Tier One modernizes 300 stops along two of GRTC's busiest routes with each stop receiving upgrades that include new flags with clearly visible route and bus stop numbers as well as eye-level, easy-to-use printed schedule and map information.
The keynote address, "Driving Excellence" will be delivered on Tuesday, Sept. 29, at 11 a.m. by Mark Aesch, CEO of TransPro, a management consultancy that guides transit systems.
The changes are aimed at improving bus operations and reducing congestion in the terminal that can stretch back out into the inbound Lincoln Tunnel and beyond.
The 8.3-mile route, with a proposed 27 stops, would replace the Capital Area Transportation Authority's current Route 1 from downtown Lansing to the Meridian Mall. Results from the plan's environmental assessment study are expected to be shared at a public hearing this fall.
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Home > Press > BioSante Pharmaceuticals Reports
BioSante Pharmaceuticals, Inc. (NASDAQ: BPAX) today reported its September 30, 2007 cash balance and its financial results for the third quarter and nine months ended September 30, 2007.
The Company's cash, cash equivalents and short-term investments as of September 30, 2007 were approximately $29.4 million, as compared to approximately $11.5 million on December 31, 2006. The Company's cash burn rate in the last quarter of 2007 is expected to be approximately $750,000 per month as its LibiGel® (transdermal testosterone gel) Phase III clinical development progresses for the treatment of female sexual dysfunction.
BioSante incurred a net loss of approximately $1.7 million (or $0.06 per share) for the quarter ended September 30, 2007 and $5.9 million (or $0.24 per share) for the nine months ended September 30, 2007, compared to a net loss of $0.7 million (or $0.03 per share) and $6.2 million (or $0.30 per share) for the same periods in 2006.
About BioSante Pharmaceuticals, Inc.
BioSante is developing a pipeline of hormone therapy products to treat both men and women. These hormone therapy products are gel formulations for transdermal administration that deliver bioidentical estradiol and testosterone. BioSante's lead products include Elestrin™ (estradiol gel) developed through U.S. Food and Drug Administration (FDA) approval by BioSante indicated for the treatment of moderate-to-severe vasomotor symptoms associated with menopause, marketed in the U.S. by Bradley Pharmaceuticals, Inc., BioSante's licensee, and LibiGel® (transdermal testosterone gel) in Phase III clinical development by BioSante for the treatment of female sexual dysfunction (FSD). Also in development are Bio-T-Gel™, a testosterone gel for male hypogonadism, and an oral contraceptive in Phase II clinical development using BioSante patented technology. The current market in the U.S. for estrogen and testosterone products is approximately $2.5 billion and for oral contraceptives approximately $3.0 billion. The company also is developing its calcium phosphate nanotechnology (CaP) for novel vaccines, drug delivery, and aesthetic medicine. Additional information is available online at http://www.biosantepharma.com .
This news release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The statements regarding BioSante contained in this news release that are not historical in nature, particularly those that utilize terminology such as "may," "will," "should," "would," "likely," "expects," "anticipates," "estimates," "believes," "plans," "hopes," or comparable terminology, are forward-looking statements. The statement regarding BioSante's expected cash burn rate for fourth quarter 2007 is a forward-looking statement. Forward-looking statements are based on current expectations and assumptions, and entail various risks and uncertainties that could cause actual results to differ materially from those expressed in such forward-looking statements. Important factors known to BioSante that could cause actual results to differ materially from those expressed in such forward-looking statements include the difficulty of developing pharmaceutical products, obtaining regulatory and other approvals and achieving market acceptance, the success of clinical testing, and other factors identified and discussed from time to time in BioSante's filings with the Securities and Exchange Commission, including those factors discussed in BioSante's most recent annual report on Form 10-K and subsequent quarterly reports on Form 10-Q, which discussions also are incorporated herein by reference. All forward-looking statements speak only as of the date of this news release. BioSante undertakes no obligation to update or revise any forward-looking statement, whether as a result of new information, future events or otherwise.
For more information, please click here
Alan Zachary, (312) 944-6784 ext. 316
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(540): View more from Virginia
she says it's "been amazing lately"
(540): View more from Virginia
i think basically because i hate her so much i'm trying to break her in half
Tap Here to view the Mobile Optimized TFLN
she says it's "been amazing lately"
i think basically because i hate her so much i'm trying to break her in half
Seeing Harry Potter 3D stoned: Pro- giant redheads w/cute accents. Con-weeping for stoners who only had Pink Floyd laser shows.
I'm pretty sure she sent a group text out saying that I was the one to get with her last night and sorry to everyone who didnt make it.
we were going to warn you, but we veto-ed that idea somewhere between "this is the stupidest thing we've ever done" and "let's order a pizza"
Dude a guy just showed up with alcohol and a bag of double cheese burgers. I think I found my future husband.
The first song on his sex mix was "highway to the danger zone"
Dude, i don't know. I don't remember anything after we started chanting/playing "shot of gin."
its weird that my cat bites every fat chick i bring home. i repeat every fat chick, qhT KINDA FRIEND ARE YOU
we're going to the olympic park to run the 100m yeaaaahhh
Apparently my Ambien addled brain last night actually did decide to go ahead and photoshop you into various animal and human molesting scenarios. That's a hell of a thing to wake up to.
Oh my lord it is too early in the morning to be that horny freak
You know you're a heffer when you discover chocolate frosting on your smoking apparatus
Like how hard is it to come up to me with chocolate and wine and say "hey, you're beautiful. Wanna marathon Doctor Who in sweatpants?" Hell yes!
You're an independent woman who is defined by her own actions and not by whether or not you have a man. You also have great tits.
I have bits of ceiling fan all over now


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About سيكس حريم خليجيات
سيكس حريم خليجيات How to avoid the 7 biggest, most costly mistakes you can make as a Forex trader. سيكس حريم خليجيات So you need great analytics, great marketing skills, great programming and great content production.
35 of the very best, most important Forex day trading tips you need to know to ensure your long-term success. سيكس ضيني
سيكس بنات مع حيوانات So you need great analytics, great marketing skills, great programming and great content production. سيكس ضيني They would also not also work with the vendors to find the best fit for their various offers, or work with them to develop better ones. سيكس بنات مع حيوانات Maybe you�ve bought a forex system or used a trading strategy before and your trading results still weren�t up to scratch, most likely because they where useless curve fitted systems that have no use in real world trading. Also, figures from previous months can be revised. سيكس نيك خلفي موجع We trade with technical analysis and fundamentals. But even they hit the wall when it comes to passing traffic to the vendor, and few are able to impact that side to improve landing pages and the sales funnel.


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Union minister on protest arrested in Jharkhand
Ranchi: Union Tourism Minister and Congress party`s Ranchi Lok Sabha MP Subodh Kant Sahay was arrested on Tuesday as he was protesting the anti-encroachment drive in the Jharkhand capital, police said. On Tuesday, the district administration began to remove encroachments in Islamnagar and Alinagar of Ranchi on the directive of the Jharkhand High Court. In the last two weeks more than 3,000 shops, houses and other illegal buildings have been either demolished or been sealed.
Ranchi witnessed violence as the protesters blocked roads at many places by setting tyres on fire. The protesters blocked main roads and other important roads and also hurled stones on passersby and police.
Sahay along with hundreds of Congress workers, with black ribbons across their lips, staged a sit-in near Karbala Chowk. Police arrested Sahay and sent him to a camp jail.
"Police adopted repressive measures despite our protesting peacefully. Our leader and central tourism minister Subodh Kant Sahay and others were arrested. Police also fired on the mob. Many people have been injured in the firing," Jharkhand Congress spokesperson Shailesh Sinha said.
In many places in the city, police and protesters clashed. At least 13 people were injured. Police also resorted to firing rubber bullets on the crowd.
To control the situation, Ranchi district administration has imposed section 144 that prohibits the gathering of five or more people in the city.
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|Artist Details : Jacqueline Stanhope
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Jacqueline Stanhope
Jacqueline Stanhope was born in 1963 and was educated in Scotland. Facinated by horses and racing she began painting and drawing them at an early age by the young age of 10 she was using oils. She was gifted both academically as well as artistically, she began selling her work in secondary school. She left school at the age of 16 to follow her career in painting on a professional level, chosing this route over a career in medicine. She was facinated by anatomy and science more than art and started freelancing as a graphic and portrait artist. By age 21 she had undertaken work for Walt Disney and had painted football teams. Jacqueline took time out to raise a young family and then re-entered the art world by producing 'Northern Dancer & Sons' a limited edition print. This print led to a rise in her popularity with leaders in the racing world investing in her work. Her work is exhibited annually at Tattersalls December Sales which has also raised her profile with paintings being sold to clients worldwide.
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Rob Miller of ProActive Coaching will speak to the public in the Menomonee Falls High School Auditorium on Tuesday, March 11 at 7 p.m. His topic will be the "The Role of Parents in Athletics".
Falls Athletic Director Ryan Anderson was introduced to the ProActive Coaching program recently and thought it would be good for the public to know about it
"I first was introduced to ProActive Coaching at the Wisconsin Athletic Directors Association's annual conference," said Anderson. "I was immediately impressed with the messages and attitudes they brought forward. ...iit will be worth your time."
The program will be presented with help from the Menomonee Falls High School Booster Club.
Miller will also be speaking to the entire coaching staff (grades 6-12) and will be hosting a session for all members of grades 6-12 at MFHS. His session with the students will take place on Wednesday, March 12 from 1:45-3 p.m.
His session will focus on what it takes to be an athlete in 2014 and in the future. The Athletic Department will provide bussing from North Middle School.
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- Woodman's shoplifter pulls knife on employee
- Bank robbery suspect in custody
- 90-year-old Menomonee Falls woman celebrates birthday with gym staff
- Menomonee Falls considers updates to comprehensive plan


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Springfield XD9SC 9mm 3" barrel 13/16 Rnds - $489.99 shipped
|Submitted by Mel Rider on Sun, 2013-03-31 08:31
Load additional images
Price: $489.99
@Kyle's GunShop
Springfield XD9SC Black 9mm Sub-Compact 13/16+1 w/ 2 Mags & XD Gear. The Sub-Compact 3" XD pistol is the ultimate in self defense firearms.
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|Slickguns Deal - Kyle's GunShop
Sportsman's has them in stock
Sportsman's has them in stock for $429.99 (check the other listing)
At least $60 over some other
At least $60 over some other advertised prices in the past week so this is not a deal. Should be removed from the site so real deals can be posted.
Right now any kind of XD is
Right now any kind of XD is so hard to find in stock I personally think it is worthwhile to post when someplace has them in stock. It took me forever to find a XDm compact 9mm in stock.
You can find more XDs than
You can find more XDs than Glocks right now. I see Springfield XDs at LGS all day long.
You are exactly right. Anyone
You are exactly right. Anyone needing or wanting an XD doesn't have to search very hard. There other XD 9s listed, cheaper than Kyles, as I type. Not a slick deal.
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text:
Welcome to the new AT&T Community
We've got a fresh look! Take the tour to see what's new.
I have an older house and I have tried all the tricks to improve wireless from my Residential Gateway (3801hgv).
Another friend has the i38hg and plugs "just" into his phone lines and it is plug play and he has 3 around the house for coverage.
On my see attachment...I have a GREEN dsl line from the outside and a phone line....can I install a second 3801hgv and just plug it into a phone jack? Looking for ideas on better reception with this model..tks
No a second 3801 won't help nor would it be possible for a second one to connect on the same vdsl line. You can use the i38hg on a 3801 but they don't operate the same as they do on an INID. On an INID the i38hg used the phone and HPNA over twisted pair to communicate. That is why is is possible for them to communicate using the same phone line. If you do use a i38hg to extend wireless you'll actually have to feed it with an ethernet connection and not a phone line. However, the same thing can be accomplished by using a run of the mill router fed on ethernet from the 3801.
Thanks jpu0822...basically the I38G and the 3801 use a different way (phone/vdsl) of pushing the signal from what I read.
I do not have the option of running a cat 5 from my 3801 (last resort) to say another router or to the actual device (ROKU) I am trying to set up..tough area....So, is there a recommendation for say a wireless repeater or Extender to Amplify the 3801 signal? i.e. as a crow flys the 3801 (downstairs) and Roku (upstairs) are about 53ft apart...again, 1880 home, tile, interesting stuff in the walls...so, I can put a repeater/extender at least anywahere from 10-30 ft from the 8801...just looking at ideas that dont require cabling/wiring or terrible changes to the 3801 setup..thanks in advance!
I would have to agree with him on this one. That would be the easiest way to connect your Roku. If there isn't a STB fed on coax near that TV the next easiest option would probably be to purchase powerline network adapters and use those instead.
aviewer...Help me out here...the 3801 is downstairs....the tv (with roku) is upstairs...and yes the main coax from "wiring closet" feeds all tv's.....STB...I may have to google....
also, for the other post..I use the PLUG LINK but get poor 5mb speed for whatever reason...house was re-wired 10yrs ago..not sure why....playing around....
thanks for the input...help me out aviewer
wow...such a simple solution that WORKS...dang..I am a computer guy and never thought to look at the back of my dvr receiver (yup...dvr is upstairs)...but, I tested it..and it will record, playback, and watch say NETFLIX.
As of now I have not CUT everything out...I have locals with HD through 3 receivers and kept my DVR....so, just playing around....you see any issues with it? Also, I pay for 12mb and typically get 11mb...is it worth the price to pay for higher bandwidth? It's just my wife and me...and daughter when home from COLLEGE...so, we typically watch "1" tv together...againTHANKS.
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Experienced Games Designer and iOS Programmer
United Kingdom - Last active: 3 months ago - Tests: 3 - Portfolio: 3
I'm a games designer and programmer with 10 years experience making top end console games and mobile apps. I worked for Bizarre Creations as a games designer and main document architect for over 7 years, producing titles such as Project Gotham Racing 2, 3 and 4 and Blur. My main responsibilities where to write and maintain the design bible for each project, which was the go to resource for all design related information about the game. The document was used by up to 150 people in the team to make the actual game. I was also responsible for the creation of game levels and game modes inside each of the projects. I was in charge of the difficulty balancing of the game, utilising analytics and focus groups to hone each level in the game to its greatest potential. After leaving Bizarre Creations due to the closure of the studio I went to work in the mobile industry for a company called Moshen. Whilst at Moshen I was again responsible for the creation and maintenance of all app related documentation as well as becoming an experienced programmer. I worked on a number of applications in that capacity including apps for companies such as Breville and Brother. I was involved in a number of top applications, the most prominent of which being Darts Night where I was the lead designer and which achieved over 2 million downloads worldwide. Since the companies closure I have since turned to freelance work and have produced my own iOS applications which have been released on the App Store. These include The Great Big Rock Quiz, The Great Big World Football Quiz and Octogram.
Professional Writer/Editor
India - Last active: 5 months ago - Tests: 2
I am a professional writer/editor with over years of experience in the field of content creation and management. I can produce high quality, SEO friendly content for you - content that will appeal to both human readers and search engine crawlers. Contact me, so I can listen to you and understand your project. I will ask questions and create a game plan tailored to your specific requirements. Then, I will start working on your project and deliver it well within the stipulated deadline. You can reach out to me at anytime before, during or after the final submission. The idea here is to ensure that you are happy with the final product :)
Associated with: Vantage NetServices Pvt. Ltd.
Expert more in Data Entries, Accounting, some Programming.
Philippines - Last active: 09/17/2014 - Tests: 8 - Portfolio: 7
"Seeking a position at ABC Company where I can maximize my training experience, where there is a need for a variety of online management tasks including – computer knowledge, organizational abilities, business intelligence and database program use." • Verbal and written communication. • Client & partner relationship management. • Attention to detail & organized, self-sufficient & proactive, client & partner hospitality. • Decision making, critical thinking, organizing and planning. • Tolerant and flexible to different situations.
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Associated with: KHAZJAVIER
English/French/Serbian translator
Serbia - Last active: 29 days ago
Professional linguist, translator with more than 10 years experience. Translation from English and French to Serbian and vice versa. Specialization fields - economics, business and marketing translation. Trados 2009. Accurate and always on time. Transcription in English, French and Serbian.
Freelancer, Virtual Assistant
Philippines - Last active: 1 month ago - Tests: 3 - Portfolio: 1
I am an Electrical Engineer by profession with passion in technical writing and article writing. I am proficient in Microsoft office tools like Word, Excel, Power point, Outlook, Internet and also AutoCAD. I am hardworking and always strive to meet customer requirements to develop a long term relationship.
Writer/Customer Service/Phone Support/Product Analyst
Philippines - Last active: 8 hours ago
I have been working as a virtual assistant for 2 years already. Most of my jobs in the past were focused on writing, phone support and customer service. However, I also have experience in product analysis and Wordpress Management.
Associated with: CMS
Data Entry, Researcher, CSR, Transcriptionist
Philippines - Last active: 1 day ago - Tests: 7
I am currently working as a Researcher and Data Entry. I worked for 3 years in one of the biggest Call Center Company in the country. Aside from that, I have a bachelor degree in Nursing which will enable me to understand and spell medical terms efficiently
Associated with: VWP Manpower Agency
freelance contractor
Philippines - Last active: 4 days ago - Tests: 4
Seeking a position that will utilize my strong quantitative and communication skills. Particular areas of interest are data processing and research. has knowledge in xml typesetting.
Associated with: QuickNotes Group
Result-driven branding consultant, copywriter, and sales coach
United States - Last active: 2 months ago - Tests: 2 - Portfolio: 1
Hello! For 14 years I have been growing companies through effective and out-of-the-box marketing strategies. At first it was my own companies. Then friends sought me for advice and I'd get endless invitations to become their partners in existing and upcoming businesses. Before I knew, I had become a marketing consultant and was spending my days helping clients grow their businesses. I could talk about the IT company that I rebranded as technology consultants, and as results, their contracts increased 4 times in price. I could also talk about the tables and chairs company that, without spending a single dollar in advertising, got on the first page of Google, Bing, and Yahoo!, sold to government agencies, including the U.S. Navy, famous universities, and Fortune 500 companies. And I could tell you about other clients' success stories. But I'd prefer to talk about you and how to make yours a success story. --- / --- \ --- Services Description: CLIENT ACQUISITION AND RETENTION We help companies get new clients and keep the current ones. Most marketing agencies and professionals focus solely on helping their customers get new clients. They ignore that it is easier and more profitable to keep current clients satisfied than it is to get new clients. UNCOVERING YOUR REAL NEEDS We start by understanding the real needs and goals of clients and helping them getting there. The main challenge with marketing today is that there are too many choices available; it can be daunting deciding what the best strategy for your firm is. For example, people often think that they need one specific solution, say a beautiful new website. But that might not be what they really need. Chances are your site is fine, and instead of a total makeover you simply need a remodeling. Instead of simply selling you a website, we'd prefer to talk to you and understand your real goals and then create and implement a strategy to get you there. We work with firms of different sizes and budgets. We create beautiful and functional websites that clearly describe what you do, how you will defend/support your clients, and how they can contact you. Then we can get you on top of Google (but it takes time), and bring leads to your site (immediately) through online advertising (pay-per click or display ads). Also, we can increase your reputation online and help you communicate with prospective clients even before they need your services through effective social media marketing. And when you get prospects knocking on your door or calling you, we will teach you how to turn them into paying clients who will tell Here's a list of services that we provide: Branding Marketing Consulting Web Design and Development Sales Coaching Mobile Application Testing, UI/UX Website Conversion Optimization Marketing Planning Copywriting Search Engine Optimization (SEO) Graphic Design Video Production Printing Pay-Per-Click Advertisement campaign creation and management Social Media Management Web Hosting and Security Marketing Audits Branding
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Associated with: Treasurefy Marketing
Marketing Consultant, Copywriter, And Business Development
United States - Last active: 03/03/2014 - Tests: 3
Do you need someone who can make your business vision come to life? Someone who can map out the right path and then drive the implementation along the way. If you need someone who knows how to get the most out of Ontraport (OfficeAutopilot), then I'm your guy. As the former VP of Business Development at Ontraport, I worked directly with the CEO to assist over 1000 companies evaluate and implement the software. I can help you remove just about any bottle neck or implement any marketing strategy with the software. Here's the main problem I see with Ontraport (OfficeAutopilot)... If you don't know how to use the automation and others features, your business strategy is limited to what you did in the past. So you end up using it like an glorified auto-responder. And you're barely scratching the surface of what's possible for your business. I can help you better implement Ontraport in your business. Take a look. http://www.linkedin.com/in/jaymedley Specialties: Strategic Marketing Planning Marketing and Sales Funnel Automation Testing, Tracking and Marketing Optimization Sales Force Automation Hype-Free Copywriting Internet Marketing Strategy Marketing Collateral Development Evergreen Lead Generation Systems Team Building & Management Business Development/Operations Management Want to find out how I can help your next project be more successful? Let's get on the phone for free 30 minute strategy session.
Associated with: ShiftNorth, LLC


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Swedbank CEO Expects Higher Credit Rating
April 23 (Bloomberg) -- Swedbank AB Chief Executive Officer Michael Wolf discusses the company's credit rating, funding costs and the Swedish economy. He speaks with Francine Lacqua from Stockholm on Bloomberg Television's "On the Move." (Source: Bloomberg)
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The Winners and Losers of Clean Energy
34:02 - Bloomberg's Ramy Inocencio discusses the winners and losers of President Barack Obama's Clean Power Plan. He speaks with Bloomberg's Mark Crumpton on "Bloomberg Markets." (Source: Bloomberg)


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Posted by bhatiahitesh on Nov. 27, 2006
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2015 is already halfway over!! We assembled a panel of critics to pick the ...
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Posted by bhatiahitesh on Nov. 27, 2006


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July 29, 2015
A conservative lawmaker launched a provocative but unlikely effort late Tuesday to oust House Speaker John Boehner from his job. Rep. Mark Meadows, R-N.C., introduced a resolution to declare the speakership vacant, citing a series of grievances against the Ohio Republican who has held the gavel since Republicans took control of the chamber following the 2010 election.
Ted Cruz more alienated in Senate than ever
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July 29, 2015
Rand Paul embarrassed Mitch McConnell a few months ago by forcing parts of the PATRIOT Act to expire on the Senate majority leader's watch. But on Tuesday, McConnell rewarded his fellow Kentuckian by tapping him to help lead the charge to defund Planned Parenthood.
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Brand marketing communications manager jobs9,095 Jobs
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- Database Marketing Manager The Database Marketing Manager will be responsible for developing and executing winning strategic marketing plans for the Just Right by Purina (JRBPNestle Purina PetCare Company4.5 508 Reviews Nestle Purina PetCare CompanySaint Louis, MOSponsoredSave
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- Senior Manager Sports Marketing & Brand Communications (Snowboarding) At adidas, interesting, amazing and inspiring aren't just ideas. They are what we do every single day. Purpose: Drive the developmentadidas Group3.7 459 Reviews adidas GroupPortland, OR3 daysSave
- Project Manager-Advertising & Brand Communications- Integrated Marketing Communications #P include but not limited to: Manage all aspects of mass media & creative development (TV, digital video, print, radio etc.) including writing briefsDiscover Financial Services3.6 738 Reviews Discover Financial ServicesRiverwoods, IL2 daysSave
- Brand Marketing Communications Manager AGCO is currently seeking a Brand Marketing CommunicationsAGCO3.2 95 Reviews AGCODuluth, GA23 daysSave
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- Senior Manager, Digital Communications - Creative Brand Marketing Our Company is seeking an experienced, self-motivated individual with 8+ years of experience to manage digital paid media efforts, paid searchSamsung3.1 1,177 Reviews SamsungNew York, NY30 daysSave
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- Senior Manager Sports Marketing & Brand Communications, Snowboarding - Fashion Industry Opportunity Purpose: Drive the development of an integrated sports marketing and marketing communications package to support adidas snowboardings global andAdidas3.7 459 Reviews AdidasNew York, NY1 daySave
- Sr. Manager, Marketing - Brand Communication The Senior Manager, Marketing Brand Communication will lead the company inDexCom3.2 40 Reviews DexComSan Diego, CA30+ daysSave
- Sr. Communications Manager Talent Brand Marketing Our Vision At Capital One, we think big and do big things. We were the first company to develop and offer mass customization and personalization ofCapital One3.6 2,316 Reviews Capital OneMcLean, VA30+ daysSave
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- Database AnalystApply on GlassdoorInternet Retailer, the world's leading publisher of e-commerce news and analysis, seeks an energetic and motivated database analyst to join itsVertical Web MediaVertical Web MediaChicago, IL2 daysSave
- Senior Account ManagerApply on Glassdoor• Manage Day-to-Day Client Services • Be key point of contact – route communication among client, partners, creative, and production servicesGraphiti Associates, IncGraphiti Associates, IncSeattle, WA9 daysSave
- Graphic Designer This person... • Is passionate about design • Is an excellent communicator, bothPerforce Software3.7 18 Reviews Perforce SoftwareAlameda, CA18 daysSave
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- Database Marketing Manager The Database Marketing Manager will be responsible for developing and executing winning strategic marketing plans for the Just Right by Purina (JRBPNestle Purina PetCare Company4.5 508 Reviews Nestle Purina PetCare CompanySaint Louis, MO16 daysSave
- Web Project Manager (Contract-full time)Apply on GlassdoorYou are a Web Project Manager with 3+ years of experience as a Project Manager or Project Lead. You're a self-starter, eager to work as a dedicatedFlickerbox, Inc.Flickerbox, Inc.San Francisco, CA2 daysSave
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Ours is the first generation to be brought up on a diet of pesticides. Already there's been an increase in crippling medical conditions. What do we have to look forward to if the prevalence and consumption of GMOs continues?
"if you put a label on genetically engineered food you might as well put a skull & crossbones on it." -president of Asgrow Seed Co., a subs. of Monsanto. "Monsanto should not have to vouchsafe the safety of biotech food. Our interest in in selling as much of it as possible. Assuring its safety is the FDA's job." -Monsanto's director of corporate
Monsanto - THIS IS BEYOND SAD!!! PLEASE EVERYBODY LEARN ABOUT THIS POISONING OF AMERICA- BOYCOTT GMO'S & ONLY BUY ORGANIC!! SIGN PETITIONS SAY NO TO GMO'S IN THE USA!!!


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RAFTsomes Containing Epitope-MHC-II Complexes Mediated CD4+ T Cell Activation and Antigen-Specific Immune Responses
- Qian Ding,
- Jian Chen,
- Xiaohui Wei,
- Wenqiang Sun,
- Junhua Mai,
- Yanzhu Yang,
- Yuhong Xu
- … show all 7 hide
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To develop a liposome formulation incorporating antigen-presenting cells (APCs) membrane microdomains with enriched epitope/MHC complexes to evaluate the activities of these liposomes (RAFTsomes) to activate T cells and prime immune responses.
We isolated membrane microdomain structures that contained the epitope/MHC complexes from ovalbumin (OVA) primed dendritic cells (DCs), and reconstituted them on liposomes surface by detergent dialysis. The resulted RAFTsomes were purified by density gradient centrifugation. Their T cell activation functions were evaluated by IL-2 secreting and proliferation assays in vitro. In vivo immune responses and the protective effect against OVA expressing EG.7 tumor challenge were also examined.
Membrane microdomains containing enriched epitope/MHC complexes can be reconstituted into liposomes with defined size and composition. The integrity and activities of these complexes after reconstitution were confirmed by in vitro T cell assays. OVA epitope loaded RAFTsomes injected in vivo resulted in high anti-OVA IgG production (predominantly IgG1). The immunized mice were protected from EG.7 tumor cell inoculation challenge.
Based on these findings, we propose that RAFTsomes can be prepared with unique properties that may be used as an antigen delivery system for immunotherapeutic applications.
- Title
- RAFTsomes Containing Epitope-MHC-II Complexes Mediated CD4+ T Cell Activation and Antigen-Specific Immune Responses
- Journal
Pharmaceutical Research
Volume 30, Issue 1 , pp 60-69
- Cover Date
- 2013-01
- 10.1007/s11095-012-0849-7
- Print ISSN
- 0724-8741
- Online ISSN
- Publisher
- Springer US
- Additional Links
- Topics
- Keywords
- dendritic cell
- immunotherapy
- lipid raft
- liposome
- Industry Sectors
- Authors
- Qian Ding (1)
- Jian Chen (1)
- Xiaohui Wei (1)
- Wenqiang Sun (1)
- Junhua Mai (2)
- Yanzhu Yang (1)
- Yuhong Xu (1)
- Author Affiliations
- 1. School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, People's Republic of China
- 2. School of Life Science and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, People's Republic of China


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FlashForward 2009 | TV Show Watchlist
Season 1, Episode 16 Let No Man Put Asunder
First Aired: April 15, 2010
Demetri decides to rush his wedding plans with Zoey after the captured FBI mole confirms his death date; Wedeck helps Aaron infiltrate Jericho in order to rescue Tracy; Olivia's friendship with Lloyd grows stronger.
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Elizabeth Sung Elizabeth Sung Saayo Noh
Milauna Jemai Milauna Jemai Susan
James Gleason James Gleason Rev. David Mullen
Anthony Skordi Anthony Skordi Judge
Michael Massee Michael Massee Dyson Frost
Stefan Marks Stefan Marks Assistant U.S. Attorney
Ryan Wynott Dylan
Lawrence A. Mandley Lawrence A. Mandley Kent Nelson
Lennon Wynn Lennon Wynn Charlie
Lee Thompson Young Agent Gough
Carrie Genzel Carrie Genzel FBI Agent Counter
Barry Shabaka Henley Barry Shabaka Henley Agent Vreede
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- Premiered: September 24, 2009
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in OhioIf barry had sons,they would act like them.
Probably would. My girlfriends and I have wizened up to the BS of the news about obama. 0bama fooled us plenty back in '08. Now I know what it is like to be raped.Romney is our man! He is a hunk too boot!!! <3
More like the right wing fringe. They also wanted to blow up the Federal reserve. Now who is that the target for? They were your typical birther militia crowd.


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Risk Quantitative Analyst. The Risk/Quantitative Analyst role will be broad in nature and will have a wide range of responsibilities, including calculating...
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Cyber Security Analyst, Senior
Applied Memetics LLC (AM LLC) is seeking a Cyber Security Analyst (senior). The successful candidate will be working with security analysts to ensure data protection and system access are properly deployed. Must possess creative problem solving skills and experience in managing teams of security analysts in making certain that the computer systems are secure from hacking and virus attacks, ...
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Articles tagged walter hyatt
14 Feb 2008 // 10:00 PM
What these songs share in common is Hyatt's smooth vocals. He never sings staccato. The lyrics flow like honey from his mouth.READ more
//Mixed media
Dead Rock West "The Price of Love" (video) (premiere) // Music
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A Chat with José González at Newport Folk Festival
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Over 50% of PSU students report having 4 or fewer drinks each week, if they drink at all.
Fact taken from 2015 NH Higher Education on line Alcohol and Drug Survey at PSU.
Fall Sports
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Over 50% of PSU students report having 4 or fewer drinks each week, if they drink at all.
Fact taken from 2015 NH Higher Education on line Alcohol and Drug Survey at PSU.
The contents of this Web site and the resources linked to it are intended for educational and informational purposes only. Nothing you read on this Web site is meant to diagnose, substitute for, or otherwise replace actual face-to-face professional counseling.
To honor her mother's memory, Shaughn Bolton established a scholarship to support environmental science and policy students—tomorrow's environmental leaders.
There's more to PSU's student-athletes than excellent grades and athletic prowess. There's a desire to make a difference in the world. Plymouth State men's hockey coach Craig Russell '09 encourages his team to serve as often as possible. Through the nonprofit organization Team IMPACT, which pairs children with life-threatening or chronic illness with local college […]
Zara Jakubas '16 and her sister Sunny '18 grew up in Califon, New Jersey, a small Victorian-style town of just over 1,000 residents. It's here that the two sisters took up tennis…
Partly Cloudy. Temperature: 75; Wind: WNW at 9; Conditions as of Tue Aug 04 at 03:00 PM EDT courtesy of The PSU Weather Center
Plymouth State University Counseling & Human Relations Center. 17 High Street Across from Hyde Hall, MSC #26. Plymouth New Hampshire 03264-1595 Call: (603) 535-2461.
Plymouth State University. 17 High Street. Plymouth, New Hampshire, 03264-1595. Main Switchboard: (603) 535-5000.
A member of the University System of New Hampshire. © 2006-2015. All rights Reserved.


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- LAST BLUE BUS: 5/15, 6:20 p.m. HC to BMC
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High: 86° Low: 61°
Sunny to partly cloudy
High: 82° Low: 64°
Some sun, then clouds
Google's System Design Change
Some may have noticed that Gmail's menu items (Calendar, Drive, etc.) are no longer appearing at the top of the email window. You will now find the addition features by clicking the "grid" icon in the top right corner of your email, next to your name.
For more information, visit: http://iits.haverford.edu/services/haverapps/.
As always, feel free to contact email@example.com with any questions.


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From The Collaborative International Dictionary of English v.0.48 [gcide]:
Burn \Burn\ (b[^u]rn), verb (used with an object) [imp. & p. p. {Burned} (b[^u]rnd) or {Burnt} (b[^u]rnt); p. pr. & vb. n. {Burning}.] [OE. bernen, brennen, verb (used with an object), early confused with beornen, birnen, verb (used without an object), AS. b[ae]rnan, bernan, verb (used with an object), birnan, verb (used without an object); akin to OS. brinnan, OFries. barna, berna, OHG. brinnan, brennan, G. brennen, OD. bernen, D. branden, Dan. br[ae]nde, Sw. br[aum]nna, brinna, Icel. brenna, Goth. brinnan, brannjan (in comp.), and possibly to E. fervent.]
1. To consume with fire; to reduce to ashes by the action of heat or fire; -- frequently intensified by up: as, to burn up wood. "We'll burn his body in the holy place." --Shak.
2. To injure by fire or heat; to change destructively some property or properties of, by undue exposure to fire or heat; to scorch; to scald; to blister; to singe; to char; to sear; as, to burn steel in forging; to burn one's face in the sun; the sun burns the grass.
3. To perfect or improve by fire or heat; to submit to the action of fire or heat for some economic purpose; to destroy or change some property or properties of, by exposure to fire or heat in due degree for obtaining a desired residuum, product, or effect; to bake; as, to burn clay in making bricks or pottery; to burn wood so as to produce charcoal; to burn limestone for the lime.
4. To make or produce, as an effect or result, by the application of fire or heat; as, to burn a hole; to burn charcoal; to burn letters into a block.
5. To consume, injure, or change the condition of, as if by action of fire or heat; to affect as fire or heat does; as, to burn the mouth with pepper.
This tyrant fever burns me up. --Shak.
This dry sorrow burns up all my tears. --Dryden.
When the cold north wind bloweth, . . . it devoureth the mountains, and burneth the wilderness, and consumeth the ??ass as fire. --Ecclus. xliii. 20, 21.
6. (Surg.) To apply a cautery to; to cauterize.
7. (Chem.) To cause to combine with oxygen or other active agent, with evolution of heat; to consume; to oxidize; as, a man burns a certain amount of carbon at each respiration; to burn iron in oxygen.
{To burn}, {To burn together}, as two surfaces of metal (Engin.), to fuse and unite them by pouring over them a quantity of the same metal in a liquid state.
{To burn a bowl} (Game of Bowls), to displace it accidentally, the bowl so displaced being said to be burned.
{To burn daylight}, to light candles before it is dark; to waste time; to perform superfluous actions. --Shak.
{To burn one's fingers}, to get one's self into unexpected trouble, as by interfering the concerns of others, speculation, etc.
{To burn out}, (a) to destroy or obliterate by burning. "Must you with hot irons burn out mine eyes?" --Shak. (b) to force (people) to flee by burning their homes or places of business; as, the rioters burned out the Chinese businessmen.
{To be burned out}, to suffer loss by fire, as the burning of one's house, store, or shop, with the contents.
{To burn up}, {To burn down}, to burn entirely.
From The Collaborative International Dictionary of English v.0.48 [gcide]:
Burning \Burn"ing\, noun The act of consuming by fire or heat, or of subjecting to the effect of fire or heat; the state of being on fire or excessively heated.
{Burning fluid}, any volatile illuminating oil, as the lighter petroleums (naphtha, benzine), or oil of turpentine (camphine), but esp. a mixture of the latter with alcohol.
{Burning glass}, a convex lens of considerable size, used for producing an intense heat by converging the sun's rays to a focus.
{Burning house} (Metal.), the furnace in which tin ores are calcined, to sublime the sulphur and arsenic from the pyrites. --Weale.
{Burning mirror}, a concave mirror, or a combination of plane mirrors, used for the same purpose as a burning glass.
Syn: Combustion; fire; conflagration; flame; blaze.
From The Collaborative International Dictionary of English v.0.48 [gcide]:
1. That burns; being on fire; excessively hot; fiery.
2. Consuming; intense; inflaming; exciting; vehement; powerful; as, burning zeal.
Like a young hound upon a burning scent. --Dryden.
{Burning bush} (Bot.), an ornamental shrub ({Euonymus atropurpureus}), bearing a crimson berry.
From WordNet (r) 3.0 (2006) [wn]:
1: of immediate import; "burning issues of the day"
1: the act of burning something; "the burning of leaves was prohibited by a town ordinance" [syn: {burning}, {combustion}]
2: pain that feels hot as if it were on fire [syn: {burn}, {burning}]
3: a process in which a substance reacts with oxygen to give heat and light [syn: {combustion}, {burning}]
4: execution by electricity [syn: {electrocution}, {burning}]
5: execution by fire [syn: {burning}, {burning at the stake}]
6: a form of torture in which cigarettes or cigars or other hot implements are used to burn the victim's skin
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From the FCC website, "The Telecommunications Act of 1996 is the first major overhaul of telecommunications law in almost 62 years. The goal of this new law is to let anyone enter any communications business -- to let any communications business compete in any market against any other."
I am a communications business and I want to compete in the C-SPAN HD, C-SPAN2 HD and C-SPAN3 HD online commentary marketplace. Comcast is using it's monopoly position as my cable provider to prevent me from having access to C-SPAN2 HD and C-SPAN3 HD. Therefore, I am unable to compete in the HD Congressional Commentary marketplace. This is bad for DEMOCRACY and it is bad for the INDEPENDENT JOURNALISTS in Comcast's service area. This reduces diversity of opinion in the Congressional Commentary marketplace and leads to the American citizens getting their news only from official sources, such as the major broadcast networks, cable networks and movie companies such as the NBC companies.
Here is a copy of an e-mail I sent to the FCC:
Subject: Comcast refuses to carry C-SPAN2 and C-SPAN3 HD because they are not PROFITABLE.
Date: Mon, 27 Jul 2015 22:44:43 -0700
From: Ken M.
To: firstname.lastname@example.com, email@example.com, email@example.com, email@example.com, email@example.com, email@example.com, email@example.com
Subject: CIMS00005891453 - FCC Consumer Center response from representative TSR58
Date: Tue, 28 Jul 2015 13:13:37 -0400
From: email@example.com
Organization: FCC
To: Ken M.
You are receiving this email in response to your inquiry to the FCC.
Dear Mr. M.,
Thank you for your e-mail to Chairman Tom Wheeler regarding C-Span in HD.
Cable TV companies are not required to carry C-SPAN in HD. C-SPAN is sponsored by the cable TV industry. The letters stand for "Cable Sponsored Public Affairs Network."
Thank You.
You are receiving this e-mail regarding your inquiry/complaint. Please note that this mailbox does not accept inbound e-mail. Do not attempt to respond to this e-mail message.
If you need additional information regarding your inquiry/complaint, our Consumer & Mediation Specialists are available Monday through Friday, 8 a.m. to 5:30 p.m. ET to assist you at 1- 888-CALL-FCC (1-888-225-5322) voice or 1-888-TELL- FCC (1- 888-835-5322) TTY. Please save the case number and refer to it when following up with the FCC.
Representative Number : TSR58