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(Lincomycin hydrochloride) THEN AND NOW VOLUME: 2 AT EVERY CORNER OF LIFE. LYNX (Lincomycin) Endorsed by the Medical Profession for over 2 decades Each ampoule undergoes 22 days of stringent tests before release Unmatched quality ensures consistent results LYNX - PENETRATES - LYNX WORKS I N D E X CONTENT page INTRODUCTION TO LYNX . . . . . . . . . . . . . . . . . 02 PART - I LYNX THEN AND NOW Skin And Soft Tissue Infections . . . . . . . . . . . . . . . 03 Bacterial Pneumonia . . . . . . . . . . . . . . . . . . . . . . . 05 Osteomyelitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 06 Tonsillitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 08 Chronic Otitis Media . . . . . . . . . . . . . . . . . . . . . . . 10 Diabetic Foot Ulcer . . . . . . . . . . . . . . . . . . . . . . . . 11 Dental Infections . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Pelvic Inflammatory Disease . . . . . . . . . . . . . . . . . 13 Acne. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 PART - II LYNX TESTIMONIALS. . . . . . . . . . . . . . . . . . . 15-26 CLINICAL ADVANTAGES OF LYNX . . . . . . . . . . 27 LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 1 INTRODUCTION LYNX, containing Lincomycin, is an antibiotic that has been tried, tested and accepted by a growing number of medical practitioners. Amongst these medical practitioners are prominent personalities from various specialities. As LYNX from Wallace Pharma enters its 22nd year, it can be rightly called an antibiotic that has withstood the test of time. We attempted to gauge the standing of LYNX among the medical fraternity by requesting top doctors throughout India to give us their feedback on LYNX. We were pleasantly surprised by the overwhelming response we received. To express our gratitude to all you Doctors who took time off your busy schedule to write to us, a booklet on LYNX with a few of your letters was published earlier. LYNX Then and Now is our modest attempt to further this. This booklet is presented in two parts. Part I is based on various indications for LYNX. It outlines the historical reports and compares it with recent inputs from esteemed doctors in similar indications. Part II presents a few of the many valuable testimonials by eminent doctors. We wish to thank each one of the doctors for their generous contribution. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 2 PART I LYNX THEN AND NOW SKIN AND SOFT TISSUE INFECTIONS LYNX THEN: Skin and soft tissue infections are very common indications seen by General Practitioners and Dermatologists alike. A wide range of antibiotics have been used for their treatment. Koven1, in a report on the use of Lincomycin in surgical infections, used Lincomycin in the treatment of 16 patients with Staphylococcal abscesses and in 5 patients with infected wounds. The results after seven days' treatment with Lincomycin, were reported as excellent in 15 of those with abscesses and improvement was reported in one. There were no failures. In a few patients, Lincomycin was combined with incision and drainage. In all 5 patients treated for wound infections, the results were said to be excellent. Holloway and Scott2 also reported on the use of Lincomycin in the treatment of 13 patients with Staphylococcal wounds and Soft Tissue Infections. The results were good in 12 of the 13 patients treated. The single poor result occurred in a patient in whom the cultures revealed Pseudomonas in addition to S. aureus. Since strains of Pseudomonas are usually resistant to the action of Lincomycin, it is not surprising that a poor result was obtained in this individual. Byakod and his colleagues3 used Lincomycin in 13 patients who were under treatment for Postoperative Wound Infections. In 12 patients, the organism isolated was S. aureus. In 1 patient, Beta-hemolytic Streptococcus and S. aureus were isolated from the wound. These patients were treated for 5 to 15 days and good or excellent results were reported in all 13. These same investigators also treated 4 patients in whom the diagnosis was Pyogenic Abscess. In three, the organism isolated was S. aureus and in the fourth, the organism isolated was Beta-hemolytic Streptococcus. Results were good or excellent in all four patients treated for pyogenic abscess. In a report on the use of Lincomycin in the treatment of Penicillin-resistant Staphylococcal Infections in children, Bentley and Pollock4 successfully treated 4 children for Wound Infections and 3 children for Cervical Abscesses. Each patient received Lincomycin by mouth, either in the form of capsules or a syrup. The total daily dose used was 30 mg per kg. References: 1. Koven. I. H. College of General Practice of Canada Journal, 1-3 March 1967. 2. Holloway, W.J. and Scottt, E.G, Amer. J Med. Sci, 249:691-695,1965 3. Byakod, B.G., Dave, B. T., Gulati, O,D., Gokhale, S.D., and Sayed, B.A, Chemotherapia, 10:53-60, 1965. 4. Bentley, J.F.R and Pollock, D., Arch. Dis Child., 43:58-61, 1968. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 3 LYNX NOW: 1. "LYNX capsules and injections are the best for treating complicated wounds and mixed infections." Dr. (Mrs) Shama Choudhary, B.Sc., M.B.B.S., M.S., Gohalpur, Jabalpur. 2. "I have used Inj. LYNX extensively in my Hospital for superficial wound infections, and as prophylactic for wound care. It is inexpensive but a definite anti-staphylococcal antibiotic on which you can rely. It is safe to be prescribed on an out patient basis by GPs also." Dr. Milind Patwardhan, M.S. (Ortho), FRCS(U.K), D.Ortho, Ratnagiri. 3. "I have used LYNX 500 in Soft Tissue Infections like Boils, cellulitis, Stitch abscess with excellent results. I have also used it with Amikacin in Intra abdominal infections like Appendicitis, and there was no need of Metronidazole. It is a very good molecule which has maintained sensitivity till date and I think it should be used more often by Surgeons." Dr. Zainul Abedin Z. Bhaisaheb, M.S, F.I.C.S, M.B. Mohammed Ali Road, Mumbai 4. "I have been prescribing LYNX (Lincomycin) for last 15 years. I am fully satisfied with results in indication like Soft Tissue Infections. No resistance so far has been noted in my practice. It is a very useful drug in skin as well as soft tissue infection especially in staphylococcal infection. No reaction is noted so far and it is useful in all age group patients" Dr. G. H. Kataria, M.B.B.S, Jamnagar 5. "I am using Capsule LYNX in all types of patients having Skin and Soft tissue infection for years and found a very good efficacy, at a very low cost of therapy. Till today, there is no adverse reaction on using LYNX." Dr. Subhasis Panda, B. H. M.S., (Cal. University), Midnapur LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 4 BACTERIAL PNEUMONIA LYNX THEN: In bacterial pneumonias seen in the outpatient, most cases are attributed to Streptococcus pneumoniae and are not always easy to diagnose. Fever, dyspnea and pleuritic pain may be seen 24 hours before radiologic signs appear. Staphylococcal pneumonia occurs somewhat frequently in postinfluenzal patients and in patients with an impaired host defense system. In this type of pneumonia, abscesses occur and may rupture into the pleural space. Numerous investigators have cited the value of Lincomycin in treating pneumonias, Pneumococci were the primary pathogens involved in these studies. Herrell noted that in Bacterial Pneumonia, the response to Lincomycin, 600 mg four times a day, was either comparable to or slightly inferior to those obtained with penicillin G and that Lincomycin was an adequate substitute in patients who are allergic to penicillin1. In 1981, Severo in Brazil studied 30 patients over 12 years of age with confirmed Acute Lower Respiratory Tract Infection. They received 600 mg Lincomycin intramuscularly every 12 hours for 7 to 15 days. Lincomycin was effective in the treatment of 27 of 30 patients. One patient with Lung Abscess was cured in 15 days.2 References: 1. Herrell WE (1969) Lincomycin Chicago, Modern Scientific Publications. 2. Severo V (1981) Rev Bras Clin Ther 10-681 LYNX NOW: 1. "LYNX is really a wonderful drug. It is not only in reach of everybody but it also has a very fantastic spectrum. I prefer LYNX in Soft Tissue and Skin Infections, Upper Respiratory and Lower Respiratory Infections. I appreciate the efforts of Wallace Pharmaceuticals for providing such a beautiful gift." Dr. Ravinder Gupta, M.B.B.S, M.D., DCH, Jammu 2. "I prescribe LYNX 1ml and 2 ml since 30 years with confidence in many bacterial infections. Now a days, many antibiotics are coming out in market but the price of LYNX is affordable for the lower class. This is being used by me since long years due to success rate of at least 90%." Dr. S. N. Yadava, M.B.B.S, M.D., F.C.G.P., F.C.C.P, Samastipur 3. "I have been using LYNX for nearly last 2-3 years, specially in Respiratory Tract Infections and in patients with Skin and Soft Tissues Infections and found very rewarding results with the drug, especially with Staph. group of organisms." Dr. Manas Chakravarty, M.D (Med), New Delhi 4. "I am prescribing in my day to day practice LYNX caps and injection for U.R.T.I, Skin disease, for period of 7 days. Result is excellent and I am quite satisfied." Dr. A. Chakraborty, M.D (Cal), Kolkata 5. "I have been extensively using LYNX, 2 ml injection in Upper, Lower RTI, Skin and Soft Tissue Infection usually for 5-7 days as OD dose. I am satisfied with the efficacy of this product." Dr. S. N. Sarma, M.D. Medicine, Nalbari LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 5 OSTEOMYELITIS LYNX THEN: In an editorial on the use of Lincomycin in the treatment of Staphylococcal Osteomyelitis, Herrell outlined the following criteria to be used if an antibiotic is to be effective in the treatment of osteomyelitis: 1. It should concentrate well in the bone. 2. It should be highly active against penicillinase producing as well as nonpenicillinase-producing Staphylococci. 3. The development of resistance, if it does occur, should be slow or delayed. 4. It should show little or no cross-resistance with the commonly used antibiotics. 5. It should be relatively nontoxic permitting its prolonged use in the treatment of Chronic Osteomyelitis. Lincomycin satisfies these criteria in that it is well concentrated in the bone. There are also adequate data in the medical literature1,2 suggesting that Lincomycin is an active, effective agent against Staphylococci, both penicillin-sensitive and penicillin-resistant. Kaplan and his colleagues3 have shown that lincomycin resistance develops slowly in vitro, with very few instances of resistance developing in vivo. Cross resistance with other types of antibiotics has not played a significant role in the therapeutic experience with Lincomycin. 4 Murdoch et al5 make reference to 52 patients who had been treated with Lincomycin. Of 16 of these patients with Acute Osteomyelitis, 15 achieved successful outcome and one was considered a failure. In 36 patients with Chronic Osteomyelitis, 28 were considered good results and 8 were treatment failures. Of the treatment failures, 3 patients experienced superinfection with Gram negative organisms, three patients had a prosthesis as the underlying reason for failure, and in two there was severe underlying rheumatoid arthritis which prevented successful outcome of therapy. Murdoch states that in view of their experience in the treatment of Osteomyelitis, Lincomycin hydrochloride would appear to be the drug of first choice in Acute or Chronic Staphylococcal bone or joint disease. He further reports that Lincomycin resistance is not rapidly acquired by Staphylococci and the antibiotics are also active against L-forms. Because of its high bone and joint penetration and its lack of toxicity, Murdoch implies that Lincomycin may be given for prolonged periods of time to patients with long standing Chronic Suppurative Osteomyelitis owing to S. aureus. Hnatko6 reported on 15 patients with Osteomyelitis caused by S. aureus treated with Lincomycin. 5 patients had Acute Osteomyelitis; in all of these, the results were good. He also treated 10 patients with Chronic Osteomyelitis who had an average duration of disease of 7.5 years. 7 of the 10 patients recovered completely while 3 showed improvement during Lincomycin therapy. The average total dose of Lincomycin given to these patients was 160 gm. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 6 LYNX NOW: 1. "In our experience Capsule LYNX (Lincomycin) is found to be very useful antibiotic in Chronic Osteomyelitis. Patient R.P. was prescribed Cap. LYNX 500 mg tid for 3 weeks for Atrophic Infected Non-union, with implant exposed outside is now cured without any side effect." Dr. Praful Pandya M.B.B.S., M.S (Ortho)., Bharuch 2. "This is to share my experience of Inj. LYNX (Lincomycin) for the last seven years. I have mostly used Inj. LYNX 2cc Intramuscular once/day in Chronic Osteomyelitis especially. Staph aureus infection, in most of the Compound Fractures in combination with Amikacin and used oral lincomycin 250 mg in children with bicycle foot injuries. Most of the time, I have got excellent results within seven days." Dr. Umang Gandhi M.S (Ortho) Vadodara, Gujarat. 3. "I have been using LYNX Inj and tablet since about 15 years. I am quite satisfied with the result and have been using it mostly for Bone Infection and Osteomyelitis". Dr. Navin Prasad Singh MBBS(PU), MS(PU), FICS, FIAM, Darbhanga 4. "I am using Cap. LYNX 500, 8 hourly in patients of Acute & Chronic Osteomyelitis. The result is satisfactory to excellent after treatment for 6-8 weeks." Dr. Mahesh B. Patel M.S. (Ortho), Baroda 5. "I have used Cap. LYNX as well as Inj. LYNX in Chronic Osteomyelitis and primary clean surgery. I found the drug to be very effective and cost friendly. It gives excellent result against Staphlococcus which are sensitive to Lincomycin. It is very cheap compared to other antibiotics and so can be given for long time. It does not give any side effects." Dr. Tushar P. Modi M.S (Ortho), Vadodara 6. "I am using Cap. LYNX (Lincomycin Injection and Capsule) since last 13-14 years for Acute Osteomyelitis and it is very safe to give without much fear of side effects." Dr. Ashok G. Shah, M.S. (Ortho), Ahmedabad References: 1. Herrell, W.E, Clinical Medicine, 5:17-19, 1968 2. Bentley, J.F.R., and Pollock, D., Arch. Dis. Child., 43:58-61, 1968 3. Kaplan, K., Chew, W.H.,Weinstein, L., Amer. J. Med. Sci., 250:137-146, 1965 4. MacLeod, A. J., Ross, H. B. Ozere, R.L. Digout, G., and Van Rooyen, C.E., Canad. Med. Ass. I., 91:1056-1060, 1964 5. Murdoch, J. McC., Geddes, A.M., and Munro, J.F.,S. Afr. Med. J., 42:54-57, 1968 6. Hnatko, S.I., Canad. Med. Ass. J., 97:580-584, 1967. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 7 TONSILLITIS LYNX THEN: The reports of Breese and colleagues1, Jackson and associates2 and Randolph and DeHaan3 clearly indicate that, under controlled conditions, patients with Group A Beta-hemolytic Streptococcal Infections, e.g. Pharyngitis, Tonsillitis, or both, with and without Cervical Adenitis, responded to treatment with Lincomycin essentially in the same manner as those patients treated with penicillin G. Breese and his colleagues1 compared the results of 100 patients of tonsillitis who received Lincomycin to two other similar groups, one receiving penicillin G and the other, ampicillin. Assessment was made using both subjective and objective criteria of defervescence, loss of symptoms, and bacteriologic cure. No significant differences in those measured parameters were noted and all three drugs were thought to be equally effective. The Lincomycin group contained fewer failures, however. They were further elucidated in another study by Breese and co-worker4. After his first study, Breese noted that there were fewer bacteriologic recurrences in the Lincomycin treated group than in the penicillin treated group. In the study of Randolph and DeHaan3 this same difference was noted. In addition, the recurrences tended to develop earlier in the group treated with penicillin than in the patients who received Lincomycin, i.e., within the first 28 days after initial treatment. Moreover, the cultures of penicillin treated patients with recurrences quantitatively contained more organisms than did those of the group treated with Lincomycin. Enough evidence is also available from these studies to indicate that most dosage forms of Lincomycin are associated with equal efficacy, so that liquid suspensions, syrup, or drops can be employed and the same degree of response can be expected as with the capsule form. The recommended duration of therapy for mild to moderate infections continues to be 10 days and an adequate dosage schedule is 250 mg. four times daily for children of school age or 20 to 30 mg per kg daily in divided dosages for infants. In severe infections, intramuscular injection of 10 mg per kg. every 12 hours seems appropriate. References: 1. Breese, B. Disney, F., and Talpey, W., imer. J. Dis Child., 112-21-27, 1966. 2. Jackson, H. Cooper, J. Mellinger, W., and Olsen, A., J.A.M.A., 194:1189-1192,1965 3. Randolph, M., and Dehaan, R., Delaware Med. J., 2:51-62, 1969. 4. Breese, N., Disney, F., Talpey, W., and Green, J., Amer. J. Dis. Child., 117:149-152,1969. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 8 LYNX NOW: 1. "Injection LYNX is indicated for Acute Follicular Tonsillitis and Severe Granular Pharyngitis with Peritonsillar Abscess. Injection Lynx has excellent result in Acute and Chronic Tonsillitis with Upper Respiratory Tract Infection. Cap. Lynx is also helpful for follow up therapy after giving injection Lynx." Dr. Bharat Shah M.S. (E.N.T), D.L.O, Dahod 2. "LYNX (Lincomycin) is very effective in Acute Tonsillitis, it gives dramatic responses when given in injectable form within 24-48 hours. I have hardly encountered any untoward effects, have used in at least 30- 40 patients." Dr. R. K. Shah M.S.(ENT), Ahmedabad 3. "As a Allopathic Doctor I am using LYNX (Lincomycin) for my Paediatric and Adult patients since 12 years of my practice. I prefer this drug in a Pharyngitis, Tonsillitis and Acne Vulgaris. I prefer 500 mg tid or qid in adults and 30 mg/kg/day for children. I feel it is very excellent drug to be prescribed." Dr. Anand Bhokray M.B.B.S, Warangal 4. "Many a times, as an ENT Consultant come across patients with Acute Tonsillitis who do not respond to many recommended, extensively used antibiotics. In such, I was tempted to use LYNX (Lincomycin) Inj. once / day for five days. It is rightly painless and effective. Least abused molecule." Dr. Ashraf Master M. B. B.S, D.L.O, Surat 5. "In my clinical practice, I am using LYNX (Lincomycin) for more than 15 years in mainly Follicular Tonsillitis. It is a very convenient dose, once a day, given I.M. Efficacy wise 395 days is good enough to get desired results. This molecule scores over better than any antibiotic in this particular indications, rather 100% cure rate." Dr. Kailash Chaudhry M.B.B.S, Dc. CH. Ex. P.C.M.S, M.A.G.S. (USA), Chandigarh LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 9 CHRONIC OTITIS MEDIA LYNX THEN: The acute phase of otitis media is usually caused by aerobic bacteria and is easily treated. However, the chronic phase is a major therapeutic problem since its etiology involves both aerobic and anaerobic pathogens. In chronic otitis media, purulent material causes damage to the bony structures of the ear and leads to infectious complications of surrounding tissues. Symptoms include persistent elevated temperature, pain in the mastoid area and deafness. Anaerobic pathogens may be responsible for the chronic inflammation and bone erosion often observed in this disease. In a 1979 Japanese study, Sugita1 isolated the causative organisms of Chronic Otitis Media. Predominant aerobic isolates were Staphylococcus aureus, Proteus, Staphylococcus epidermidis and Pseudomonas aeruginosa. Also isolated were nine species and 81 strains of anaerobes from 62 of 760 patients with otitis media. 56 of those 62 patients exhibited mixed aerobes and anaerobes. Brook2, in another study in 1980, obtained aerobic and anaerobic cultures in 28 pediatric patients and found anaerobic bacteria in 86%. There were 26 isolates of anaerobic gram-positive cocci and 11 Bacteroides species including 4 Bacteroides fragilis and five Bacteroides melaninogenicus. These findings suggest that anaerobes, both alone and in combination with aerobes, play an important part in the etiology of Chronic Otitis Media2. In such patients, Lincomycin offers a distinct advantage by covering Staphylococcus aureus, other gram-positive aerobes and most anaerobes. References: 1. Sugita R et al (1979)(Jap)72:379 2. Brook I (1980) J. Laryngol Otol 94:607 LYNX NOW: 1. "LYNX is used in resistant case of Chronic Suppurative Otitis Media (CSOM); Acute Severe Tonsillo-Pharyngitis; Quinsy (peritonsillar abscess), CSOM with Acute Mastoiditis, Acute Pharyngitis with LRT Infection. Dosage-Adults 2ml for 7 to 10 days, Children 1ml for 7 days. Results 99% success rate Opinion-good drug". Dr. S. V. S. Suryanarayana Murthy, B.Sc, M.S. D.L.O, Razole 2. "I use LYNX 500 in Acute Tonsillopharyngitis, Chronic Suppurative Otitis Media, Dosage: T.I.D for 7 days Result: Excellent with occasional concomitant use of Aminoglycosides". Dr. Sekhar Bandyopadhyay, MBBS, D.L.O, M.S, Raiganj 3. "I am using Inj. LYNX 600 mg in Chronic Suppurative Otitis Media and in ease of chronic Purulent Maxillary Sinusitis with excellent result." Dr. R. K. Mishra, M.S., Khandwa 4. " I am writing LYNX (Lincomycin) for last 20 years in CSOM and Tonsillitis (Pediatric and Adult Patient), 30 to 50 mg/kg body weight in divided dose for 7 days." Dr. Bijoyes Ch. Kumar, Sr. ENT Surgeon, Mushidabad. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 10 DIABETIC FOOT ULCER LYNX THEN: Diabetic ulcers are the most common foot injuries leading to lower extremity amputation. Management of the diabetic foot requires a thorough knowledge of the major risk factors for amputation, frequent routine evaluation and meticulous preventive maintenance1. The majority of diabetic foot complications resulting in amputation begin with the formation of skin ulcers. Early detection and appropriate treatment of these ulcers may prevent upto 85 percent of amputations.2 Polymicrobial infections predominant in severe diabetic foot infections and include a variety of aerobic gram-positive cocci, gram negative bacteria, and anaerobes.3 Lincomycin, as it covers these group of organisms proves to be beneficial in the management of diabetic foot ulcers. References: 1. Armstrong DG, Lavery LA. Diabetic Foot Ulcers. Prevetion, Diagnosis and Classification. American Family Physician. 1998, March;1325-1336 2. Edmonds Mt. Experience in a multidisciplinary diabetic foot clinic. Jn. Connon H, Boulton AJ, Ward JD, eds. The foot in diabetes proceedings of the 1st National Conference on the Diabetic Foot, Malvern, May 1986. Chichester, N.Y:Wiley;1987:121-31. 3. Caballero E, Frykberg RG, Diabetic foot infections. J. Foot Ankle Surg.1998; 37:248-55 LYNX NOW: 1. "I am using LYNX (Lincomycin) Tab and Inj. Mainly I have used this drug in Chronic Diabetic Wounds not responding to other antibiotics and I am very happy with the result." Dr. B. T. Kurane, M.S., Pargaon. 2. "I have been using Inj. LYNX (Lincomycin) since the last 12-15 years mainly for suspected gram positive infections if Pencillin is not favoured by the patient or is allergic. The results have been gratifying especially in Multiple Abscess / Diabetic Foot / Cellulitis" Dr. S. B. Gogia, MBBS, New Delhi 3. "I am using LYNX 2ml/1ml LYNX Group from last 10 years in all types of patients without side effects. For e.g. (1) Skin & Soft Tissue Infections (2) Tonsillitis (3) Diabetic Foot Ulcer. I am fully satisfied with this product." Dr. Harsh S. Gurnani, D.H.M.S, Ulhasnagar 4. "I have been using Lynx (Inj / Oral) since last 10-15 years for Diabetic foot management. It has withstood the test of the time and still works well." Dr. Abhay Srivastav, M.S. Jabalpur 5. "Cap. Lynx 500 mg/ 250 mg found to be very useful for treatment of Non Healing Ulcers. I have rarely encountered any side effect in my surgical practice and found LYNX to be safe and effective antibiotic in both children and adults". Dr. G. Manohar, MBBS, M.S, - Vishakhpatnam LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 11 DENTAL INFECTIONS LYNX THEN: Odontogenic infection may be primary or secondary to Periodontal, Pericoronal, Traumatic or Post Surgical Infections.1 Complications of dental infections include sepsis and airway compromise (e.g. Ludwig angina, Retropharyngeal Abscess). In addition, odontogenic infections carry significant morbidity of pain and cosmetic defect. Common organism implicated are serotypes of S.mutans, Streptococci and anaerobes like Peptostreptococci, Bacteroides organisms and Fusobacterium2. Lincomycin, has a spectrum that cover all these organisms, thus proving beneficial in dental infections. References: 1. Reznick J. Infections of Odontogenic Origin Oral Health 1993, 1-6 2. Sands T, Pynn BR, et. Al. Odontogenic infections: Part two Mircobiology, antibiotics and management. Oral Health 1995;85(6):11-4 LYNX NOW: 1. "During my seven years of clinical practice, I have found excellent results with Lynx (Lincomycin). I would like to say that LYNX (Lincomycin) is meant for the Dental Infection whether Periodontal, Paediodental or Arthodental Abscess. It is very much effective against the Gram+ve organisms (such as Staph and Strep). It is economical therapy treatment per day as compared to other injectables. It has an excellent dosage convenience" Dr. Mohammad Yaqoob, MDS, Lucknow 2. "This is with reference to your excellent product Inj. LYNX (Lincomycin). I have observed excellent results in Oropharyngeal and Dental Infections and Parotitis to such extent that few dental surgeries could be avoided because of timely use of Inj. Lynx." Dr. Vidyadhar M. Bodas, MBBS, Pune 3. "LYNX (Lincomycin) is used for oral infection caused by Staph aureus and Streptococcus I use it in Acute Dental Infection with Periodontal Involvement, especially in Bone Infection in Dental Abscess and Osteomyelitis, (600 mg i.m. x daily x 5 days). It is very helpful in Mixed Dental Infection and as a Prophylactic Measure Before and After Dental Extraction." Dr. Mohammad Ayub, B.Sc, B.D.S, Srinagar 4. "We are using Inj. Lynx since last 6 years regularly in Dental practice. The main indication of injection LYNX is in severe case of Dental Infection with Abscess. After use of Inj. LYNX 2cc. IM patients get very good control and relief from infection. The total dose used is 2cc IM for 3 days. The result is all type of dental infections is always above the expectations." Dr. Tushar K. Bharwada, BDS, FPFA(USA), Surat 5. "I have been writing Inj. Lynx for a period of last 5 years, in my day to day practice. I have found that it has done wonders in patients who were not responding to antibiotics (injection) of ceftriaxone or any other ranges. I have used it in acute conditions of Oro-dental Infections, both in soft and hard tissue infections. Its results are wonderful and you can call it a wonder drug." Dr. Javaid A. Ahangar, B.Sc, B.D.S (Kud), MIDA, Srinagar LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 12 PELVIC INFLAMMATORY DISEASE LYNX THEN: Pelvic Inflammatory Disease (P.I.D) is one of the most common serious infections in women aged 16-25 years, and the morbidity produced by it exceeds that produced by all other infections combined for this age group1. Due to the polymicrobial etiology of acute PID, the optimal approach in the management of such mixed aerobic and anaerobic infections, is to use a combination of antimicrobial agents. Keeping this in mind, an open randomized, comparative study was carried out using LYNX (Lincomycin) and Amikacin in one group and Metronidazole and Amikacin in the other2. The study concluded that the combination of Lincomycin plus Amikacin was equiefficacious and better tolerated in comparison to Metronidazole plus Amikacin in acute PID patients. References: 1. Martens M. G. Pelvic Inflammatory Disease. In, Telinde's Operative Gynaecology, Rock JA, Thompson JD, eds. 8th Ed., Rippincott Raven, New York, 657-683, 1996. 2. Kulkarni S, Rao S, et.al. Efficacy and safety of Lincomycin versus Metronidazole and Amikacin in the treatment of Acute Pelvic Inflammatory Disease (PID). Indian Medical Gazette. 2003, vol.CXXXVII (8):316-324 LYNX NOW: 1. "This is to state that Inj. LYNX has good response in cases of PID (Pelvic Inflammatory Disease) and also in prophylaxis against post traumatic infection. At the same time it is economical, well tolerated and accepted by patients." Dr. (Mrs.) Chhaya Budhwani, M.D (Bom), F.C.P.S, D.G.O, DFP Hospital, Bhopal 2. "I am using Cap. LYNX in PID cases and Post Operative cases. I find very good results." Dr. Mahendra Singh, M.B.B.S, D.G.O., Satna, (M.P) 3. "Indication PID, Preoperative minor surgeries as prophylaxis as in M.T.P, D&C, L.T.T. Advantages (1) Single dose therapy, (2) Wide coverage of gram +ve organisms along with anaerobes" Dr.(Mrs) S. Zadgaonkar, M.B.B.S., M.S, Jabalpur. 4. "Capsule LYNX is very effective in post delivery with episiotomy, PID infection and post Incision & Drainage cases. Results are excellent." Dr. Neelam Gupta, M.B.B.S, Katni (M.P) LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 13 ACNE LYNX THEN: Acne is a very common infection seen by Dermatologists and General Practitioners. The currently applied topical antibiotics include Erythromycin and Clindamycin. However, due to widespread use, resistance has been developed to the commonly used antibiotics1. Hence, there is an acute need for newer topical antibiotics. An earlier in-vitro study had demonstrated that Lincomycin could inhibit the growth and extracellular lipase production by Propionibacteria.2 Thus, a recent study was conducted using topical Lincomycin for the treatment of acne.3 The trial concluded that LYNX (Lincomycin) hydrochloride gel is an effective and safe treatment option for mild to moderate Acne vulgaris. References: 1. Eady EA,Cove JH. Erythromycin resistant Propionobacteria in antibiotic treated acne patients : Association with therapeutic failure. Br J Dermatol. 1989;121: 51-57. 2. Unkles SE, Gemmell CG. Effect of clindamycin, erythromycin, lincomycin, and tetracycline on growth and extracellular lipase production by propionibacteria in vitro. Antimicrob Agents Chemother. 1982 Jan;21(1):39-43. 3. Sharma A et al. Topical Lincomycin gel in Acne vulgaris: A Multicentric Placebo Controlled Study. Ind J Dermat Venereol Lep. 2003; 69 (4): 271-273. LYNX NOW: 1. "I have used LYNX Gel and LYNX Injections extensively in my Derma practice and have come to conclude that it is best possible molecule to effectively treat Pyodermas and Acne of all varieties. Its cost effectiveness makes it more useful drug to all groups of people." Dr. Rajinder Singh, M.B.B.S, M.D (General Medicine:Heart & Chest), Ex.DRHO (Skin & V.D), Ex. C.A.S., Jammu 2. "I am very glad to give my feedback on LYNX, both injection and gel form. I have been using it for past many years since the launch. I have experienced encouraging results in Pyodermas and Acne vulgaris. I have not had any complaints of related side effects that are usually associated with other antibiotics. This has further strengthened my faith in the safe and effective products offered by Wallace Pharma." Dr. Vipin Gupta M.D Jammu. 3. "Safest and effective local antibiotic for acne is only LYNX Gel and of course capsules also." Dr. Sanjeev J. Aurangabadkar, M. B. B. S, M.D (Skin), Hyderabad. 4. "I am prescribing LYNX Gel in Acne Vulgaris (from 1st to 5th grade) for last nearly 2/3 years as topical therapy. I have found excellent results with this. I appreciate this product." Dr. K. N. Gupta, M.B.B.S, M.D., Gangapur city. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 14 PART II LYNX TESTIMONIALS GENERAL PRACTITIONERS "I am using LYNX (Lincomycin) in case there is no or poor response to routine antibiotics. The following are the indications wherein it was used: 1. Trophic ulcers of foot. 2. Diabetic non-healing ulcers. 3. Chronic pyodermas/eczemas. 4. LRTI associated with Koch's/ COPDs/ immunocompromised conditions like HIV. 5. Post operative wounds. 6. Post operative prophylaxis. 7. Pelvic Inflammatory Disease. 8. Chronic Osteomyelitis. The results are excellent." Dr. P.R. Kulkarni. B.Sc., M.B.B.S. Station Road, Miraj, Maharashtra. "I have been using Lynx (1 ml and 2 ml) since about 8 years. It is giving good results specially in Acute Bronchitis, Furunculosis, Acute Pharyngitis. It is easier to give one injection once a day. I have not found any adverse reaction. I have been practicing for more than 40 years." Dr. S. N.Chaubey. B.Sc., M.B.B.S. Sipri Bazar, Jhansi. "I am using Lynx injection and capsule for last 20-25 years in cases of Furunculosis and URTI and it is giving excellent results." Dr. Krishnakumar Shetty. M.B.B.S. Goregaon, Mumbai. "I have used widely your Lynx injection, syrup and gel in my practice for the last 10 years. I have found LYNX to be of utmost importance specially in Skin and ENT where I have got upto 90 % results. I thank you for providing such a good product for my patients." Dr. Sunil Chawla. B.A.M.S., BEHL, Bhiwani. "It is enough to say that I am using LYNX (Lincomycin) for the last 30 years that justifies my faith in its efficacy." Dr. S. Prakash. M.B.B.S., R.Z.M.C. (Lusaka), Pritam Pura, Delhi. "I am using Lynx Capsules and gel for a long time in case of Tonsillitis, Soft Tissue Infection, Furunculosis, and Chronic Suppurative Otitis Media and the results are excellent in comparison to other antibiotics." Dr. D.K. Sur, M.B.B.S., DTMH & H,C.Ac, F.C.I.P., Garifa. "I prescribe Lynx in the following conditions: 1. Tonsillitis 2.Skin and soft tissue infections. 3. Bone and joint infections. I prescribe one injection daily for 5 days. I am prescribing because of the patients compliance due to cost of therapy and also for convenient dosage schedule. I feel it is the best antibiotic for poor patients." Dr. Lalit KR. Singh. M.B.B.S., PGDCH. Mahisauri, Jamui. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 15 LYNX TESTIMONIALS GENERAL PRACTITIONERS Also Endorsed by: Dr. Naib Singh, Mullana. Dr. Arnab Ranjan Ghosh, South 24 Parganas. Dr. Avinash Chavan, Kandivli, Mumbai - 101. Dr. Ramesh Shripat, Solapur - 5 Dr. Savita Ghotikar Tanksale, Vile Parle (E), Mumbai - 99. Dr. M P Singh, Mahnar. Dr. Nandlal Jotangia, Goregaon (E), Mumbai - 63. Dr. (Mrs) Anuradha, Mahnar. Dr. Bharat Shah, Andheri (W), Mumbai - 58. Dr. B K Singh, Bidupur. Dr. Bharati Machhar, Malad (W), Mumbai - 64. Dr. B Thakur, Jamui. Dr. S. N. Sanyal, Kharagpur. Dr. Shailendra Kumar Sinha, Begusarai. Dr. Bharat Shah, Ahmedabad - 15. Dr. Arshad Hussain, Araria - 854 311. Dr. R.K. Gupta, New Delhi - 110046. Dr. N K Chatterjee, MBBS. Dr. Vivek Handa, New Delhi - 018. Dr. Hari Narayan Singh, Begusarai. Dr. Jaideep Rohatgi, New Delhi - 110006. Dr. Kishore Mhaske, Ahmednagar. Dr. GRVR Reddy, New Delhi - 018. Dr. Sagar Doshi, Indapur. Dr. U.K.Pandhya, Gotegaon - 487118. Dr. Ashok H Shah, Pune - 411042. Dr. N Y Beg, Sitapur. Dr. Mrs Anjali Ballal, Pune - 411 042. Dr. GS Singh, North 24 Parganas. Dr. S G Rai, Ganjipur (U.P). Dr. Himanshu Shukla, Sitapur. Dr. Yeshwanth N Nayak, Boloor. Dr. AS Chavan, Narsingpur. Dr. T D Ramamurthy, Mangalore - 575003. Dr. NN Srivastav, Bahraich. Dr. H Kamalesh Singh, Bangalore - 67. Dr. Ganesh Bedajna, Calcutta - 004. Dr. Umesh S N, Bangalore - 560029. Dr. Firdous Rahman, Kolkatta. Dr. M A Bindu Rani, Bangalore - 67. Dr. SK Baksh, Kolkata. Dr. B R Srinivas, Kolar Dr. SI Ansari, Kolkata. Dr. Chandrashekar N, Bangalore - 28. Dr. Vikram Atavale, Pune. Dr. B V Gopalakrishna, Bangalore - 53. Dr. VV Chavan, Pune. Dr. C U Jayaram, Mysore - 23. Dr. Sunil Sangvi, Pune -18. Dr. A Neelankanta Murthy, Mysore - 008. Dr. VVLN Rao, Behrampur. Dr. Kantha Raju, Mysore - 570 007. Dr. K S Thumar, Dhoraji. Dr. Sachin D Bonde, Dombivli (W). Dr. R N Das, Basirhat. Dr. S N Krishnan, Dombivli (W) - 421202. Dr. K B Saha, 24 Parganas (N). Dr. X. Madeline Mary Pax, Madurai - 625 001. Dr. P Ghoshal, Kolkata - 56. GYNAECOLOGIST "I have been using LYNX (Lincomycin) capsules since last 10 years. It is quite effective in P.I.D." Dr. Honey Gupta, M.S, Kota Also Endorsed by: Dr. Narendra Pawar, Vellarikundu - 671533. Dr. Hemavathi, Kolar. Dr. Mughda Kulkarni, Madhya Pradesh. Dr. Poonam Kohli, Lucknow. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 16 LYNX TESTIMONIALS GENERAL MEDICINE "Patient diagnosed with Acute Lymphangitis was prescribed Cap Lynx (500 mg) 1 capsule three times a day for 5 days. Patient responded very well to the treatment. Patient was symptom free after 5 days and there was no recurrence after 3 months. Another patient of Diabetic foot responded well after treatment with Lynx (500 mg) TDS. Patient was already on Inj. Amikacin. There was no recurrence. A patient with multiple boils on both lower limbs was given Cap Lynx (250 mg) TDS for 7 days. Patient was completely symptom free after 7 days." Dr. Tejinder Pal Singh M.B.B.S., M.D. Mansarovar Garden,New Delhi. Also Endorsed by: Dr. Anand Kumar, Samastipur. Dr. BC Patnaik, Bhubaneshwar. Dr. A R Pal, Midnapore. Dr. P R Sharma, Jammu. Dr. B Bera, Midnapore. Dr. Baljit Singh, Jammu - 180 012. Dr. Vinod Kumar Tripathi, Sitapur. Dr. V Gopalakrishna Rao, Amalapuram - 533201. Dr. Satish Mahawar, Maholi. Dr. G R K Gupta, Visakhapatnam. Dr. SS Mondal, Sirocoal. Dr. Rajesh Singal, New Delhi. Dr. NC Jain, Aashind. Dr. S Raju, Hunsur. Dr. Laxmikant Kabra, Pune. Dr. Dinesh Rajvaiwya, Pachore. Dr. BM Nene, Pune. Dr. V Radhakrishnan, Cumbum - 625 516. OPTHALMOLOGIST Endorsed by: Dr. Sanjay Bhatnagar, Patiala. Dr. S K Jha, Purnea - 2854301. Dr. Manoj Kumar, Darbhanga - 846003. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 17 LYNX TESTIMONIALS ORTHOPAEDICS "I have been using Lincomycin with brand name of LYNX, Inj. and capsules since last 15 years, particularly in contaminated road side accident and after culture sensitivity test. I have found it very effective against Staphlococcus aureus. It is true to my opinion." Dr. Atul G. Bhatt, M.S.(Ortho), Ahmedabad. "Excellent gram positive coverage with anaerobic coverage, assuring superb compliance due to once a day injectable regimen, costing very affordable- makes it my first drug of antibiotic choice (unless indicated otherwise by culture report)." Dr. Abhay Manchanda. M.S., P.G.C.R., Anup Nagar, Indore. "Why I prescribe Lynx (Injection, particularly) in general Orthopaedics practice-1. Once in a day schedule. 2. It covers most of the common pathogens one comes across in day to day practice. 3. Well suited for small hospital units where there is a shortage of trained staff, due to once a day schedule. 4. Cost effective." Dr. S.K.Jain. M.S. (Ortho), Satna. "I have been using Lynx since 2 years mainly for septic arthritis and post operative cases. Dosage schedule is 500 mg twice a day for 7-10 days. The results seem to be very good." Dr. M. Sankara Rao. M.S.(Ortho). Vizianagaram. "I have been using LYNX (Lincomycin) for the last 10 years. The indications for which I am prescribing are Chronic Osteomyelitis and Soft Tissue Infections like Cellulitis of varied aetiology. I am prescribing 500 mg twice a day for 7 days or 1 ampoule of 600 mg for 1 week with which I am getting good results. I have not observed any side effects nor any resistant cases." Dr. P. Ashok Kumar. M.S. (Ortho)., Vishakapatnam. Also Endorsed by: Dr. HS Sohal, Patials -147001. Dr. N P Singh, Purnea. Dr. B Sudhakar Rao, Paloncha - 507115. Dr. L N Mandal, Katihar - 854 105. Dr. Amirul Koda, Samastipur. Dr. P M Dhole, Ahmednager - 814 003. Dr. K.K.Das, Midnapore -721101 Dr. Amit Kumar Tripathi, Reva. Dr. Pramod Maheshwari, Madhya Pradesh Dr. Man Mohan Singh, Rewa. Dr. V.K.Kataria, New Delhi -110046. Dr. Avadhesh Kumar, Jaunpur (U.P.) Dr. Atul Chandra Agarwal, Allahabad. Dr. S N Prasad, Ganjipur Dr. Tapash Ranjan Bag, Arambagh S.D. Hospital. Dr. Shridhar Shetty, Mangalore - 575001. Dr. Jayant S Shah, Pune - 411 002. Dr. Dinesh Kumar Shetty, Karnataka - 201. Dr. Naresh Pandita, MS (Ortho). Dr. Nikhil Kumar Rai, Kundapura. Dr. Rajeev Tanwar, Hisar - 125005. Dr. Satish Babu, Palani. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 18 LYNX TESTIMONIALS GENERAL SURGERY "I am in practice for 29 years. I am using Lynx (Lincomycin injections as well as capsules) for the last 10 years in a variety of Skin and Soft Tissue Infections as well as Osteomyelitis cases. To name a few 1. Release of burn contractures and skin grafting (5 days). 2. Flap procedures (7 days). 3. Finger tip injuries with exposed bone (5 days). 4. Pulp abscess (finger) with impending osteomyelitis (7 days). 5. Trophic ulcer (Diabetes and Leprosy) with/out Osteomyelitis of tarsals and /or metatarsals in foot, (7 days). 600 mg daily intramuscularly in adults and 10 mg/kg I.M. in children for 5 to 7 days depending upon severity has given satisfactory control of infection without any side-effects." Dr. J.J.Kashalikar M.S. Plastic Reconstructive and Cosmetic Surgeon. Miraj. "We are regular prescribers of Inj Lynx since last 4 years. We are very much satisfied with the result. Where nothing works, Lynx works." Dr. Anil Singh M.S.(G. Surgery) Dr. Sunita Singh D.G.O. Itarsi. "I have been using LYNX (Lincomycin) for the last 7 years in the following indications. 1.Soft tissue infections (2 ml BD for 5 days, 250 mg capsule TID for 5 days) , 2. Upper Respiratory Tract Infection (same as above), 3. Post operative surgical case (along with Gentamicin) (2 ml for 5 days followed by 250 mg capsule TID for 5 days. I am very happy with the results. I have not seen any side effects with the above dosage as I have used in more than 4000 patients in these 7 years." Dr. P. Viswanadham M.S., Srikakulam, Andhra Pradesh "I am using Cap Lynx 500 mg 8 hourly in almost all rectal surgeries and find it works fantastically. Patients are very happy." Dr. Damodar M. Kashikar M.S.(G. Surgery) Warangal. "I write Lynx for 1. Earliest indication in any post operative erythema/wound infection- the wound heals within 72 hours. 2. Hernioplasty (mesh repair)- all cases- so no chance of mesh infection by Staphlococcus. 3. Cellulitis/Abscesses- Avoids undue I & D. 4. Resistant URTI and LRTI- especially those cases who cannot and do not want admission and injection- once a day can be taken even in any peripheral village." Dr. Nishith Gagrani. M.B.B.S., M.S. , F.A.I.S., Devas. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 19 LYNX TESTIMONIALS GENERAL SURGERY "I have been using LYNX for the last 15 years for 1. Prevention of postpartum infection. 2. Skin and soft tissue infections. 3. URTI and LRTI 4. Bone and joint infections. 5. Post operative below umbilical surgeries. For PPI I am giving LYNX 600 mg OD for two days before delivery and 3 days after the delivery both in normal and episiotomy deliveries. In post operative, below umbilical surgeries like appendicectomy, hernia, hydrocoele, piles, fistulae, hysterectomy, etc., I have found excellent wound healing without any infection with 600 mg Lincomycin IM BID on the first day followed by 600 mg IM OD for the next 6 days. In URTI and LRTI 600 mg IM OD for 5-7 days has been giving excellent results. In bone and joint infections, LYNX 600 mg IM OD for 10 days has been giving excellent results. In these 15 years I have used Lincomycin for more than 10,000 patients. I have not found any side effects and it has given excellent results." Dr. Seshagiri Rao. M.B.B.S., D.O., MAMS, Srikakulam Also Endorsed by: Dr. K S Kamath, Kasaragod - 671121. Dr. V Ananda Rao, Visakhapatnam - 13. Dr. Amarjit Singh, Patiala - 147001. Dr. D Venkateswara Rao, Visakhapatnam - 530020. Dr. Samir Kumar Dey, Calcutta. Dr. N Subba Rao, Visakhapatnam - 530 002. Dr. G K Ghosh, Contai. Dr. Vandana S Rao, Srikakulam - 532001. Dr. Navin Prasad Singh, Darbhanga - 846003. Dr. T Narayana Rao, Visakhapatnam. Dr. Atul Puranik, Mumbai-64. Dr. G Manohar, Visakhapatnam. Dr. Sarita Bhagwat, Mumbai - 14. Dr. S K Roy, Sub -Divisional Hospital. Dr. Manisha Garg, Bhopal - 462001. Dr. Arun Murari, Patna - 800 004. Dr. Nishith Gagrani, Madhya Pradesh. Dr. H Ravikumar, Bangalore - 560010. Dr. Lalit Machhar, Vadodara - 2. Dr. K.S.Gunjyal, Goa - 2514883. Dr. MA Chaudhary, Tabalpur. Dr. Dinesh Luthra, Maheshpur Chowk. Dr. Alok Kashiv, Narsingpur. Dr. R. S. Chowdhary, Aligarh. Dr. MM Bagati, Delhi - 110096. Dr. Anil Dube, Naewa Junction. Dr. Rajendra Jathar, Pune - 37. Dr. L. A. Kapadia, Ujjain, M. P. Dr. Jayaram Patro, Bhubaneshwar. Dr. V. Mahadevan, Madurai - 2. Dr. H K Dobaria, Rajkot. Dr. A. Natarajan, Palani - 624 601. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 20 LYNX TESTIMONIALS PAEDIATRICS "I am using Lynx syrup/injections for Neonatal Pustular Dermatitis, Secondary Infected Eczema, Arthritis, Scalp Cellulitis and Pyodermas with good results." Dr. Vivek Despande M.D.(Paediatrics). Ahmednagar. "I have been using Lincomycin in my practice (as Lynx) in upper Respiratory tract, Lower respiratory Tract, skin and soft tissue infections in the form of syrup, capsule and injections over a period of more than 10 years and found that the results are convincingly excellent, even if it was prescribed as lone antibiotic in all the cases (number being more than 1000)." Dr. Jitendra Agarwal M.B.B.S., M.D. (Paeds), MAMS, Ambala. "Though it has been stated in books about the serious side effects of Lincomycin, I was reluctant to prescribe it, but after seeing various references, I tried it on my patients and now I have to say- there is no need of giving any painful, hypersensitivity prone Inj. PPF. I will request all doctors to use Lynx for Multiple boils, Impetigo, Furuncles, this is having excellent result in URTI (bacterial), infected wounds, impending abscesses, cellulitis, Otitis Media, Sinusitis. As it is dose convenient and economical it makes patient compliance better, I wish success of this product." Dr. Prabhakar Avtade. M.B.B.S., D.M.C.H., Bhilwada Also Endorsed by: Dr. Mahesh Nawani, Bhopal. Dr. G S Haque, Begusarai - 851 101. Dr. M.B.De, Midnapur- 721 101. Dr. Ashwini Kumar, Gajipur. Dr. Harish Seth, Delhi - 110006. Dr. Suresh Kumar N L, Mysore - 007. Dr.NP Jain, Raipur. Dr. A. Neville Carvalho, Goa. Dr. Ashok Kumar nayak, Kandeli. Dr. Nishikant Patange, Dombivli (W) - 421202. Dr. K.K. Varma, Bharaich. Dr. Pramod Bejkar, Dombivli (W) - 421 202. Dr. R K Goel, Jammu. Dr. R S Manawat, Chomu (Jaipur). Dr. Nissar Ahmad, Jammu. Dr. R. Mahalingam, Madurai - 625 009. Dr. Gurdip Singh, Jammu. Dr. P. Ilangovan, Madurai - 20. Dr. A Razzak, Barasat. Dr. A. Jaffarullah, Palani - 624 601. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 21 LYNX TESTIMONIALS DERMATOLOGY "I am using LYNX capsules in Sexually Transmitted Diseases especially when I am confused in diagnosis or multiple STDs together. And always I am getting dramatic improvement." Dr. Kalpesh A. Shah M.D. (Dermatology & STD) Ahmedabad "I have been recommending LYNX (Lincomycin) oral and injection from 1982. I have been prescribing this drug for Chronic Superficial Folliculitis and Cellulitis and Hidradenitis suppurativa. For Chronic superficial folliculitis, I prescribe injection 600mg twice a day for 3 days followed by cap 500mg for 7-14 days. For Cellulitis, I prescribe this drug for 7-10 days. (500mg). For Hidradenitis suppurativa I advise this drug (oral)500mg for 10-14 days. I never encountered any major adverse effects in my patients except for minor G.I. disturbance. I am happy with the results in all of my patients." Dr. T. Narayana Rao M.D., D.V.D., Visakhapatanam "I have been using LYNX (Lincomycin) for the past 18-20 years. This is my drug of choice in for the following conditions. a) Gram positive infections especially i) Folliculitis ii) Superficial pustular folliculitis iii) Cellulitis iv) Impetigo b) Filarial lymphangitis where there is severe streptococcal infection. c) Hidradenitis suppurativa d) Eczematous disorders associated with severe infection. E.g. Infectious eczematous dermatitis. Treatment - 5 - 7 days 1 ampoule 600mg I.M one time in a day. Results are excellent and never I faced resistance. Only side effect is an occasional diarrhoea. One of the outstanding drug in treating gram + ve coccal infections." Dr. B.V. Ramachandra M.D.(Derm. & Ven.) Visakhapatanam "I don't hesitate to say emphatically that LYNX (Lincomycin)/500mg cap and 2ml injections) are very effective in the treatment of: 1. S.P.F. Dosage 300mg cap 1TID - 7-10 days 2. Sycosis barbe - do - 7-10 days 3. Hidradenitis suppurativa 2ml. 1 BD 2 days followed by 1 TID 500mg cap 7-10 days and I did not come across any significant side effects with LYNX (Lincomycin) during my last 15 years of its usage." Dr.T.V. Ramanarao M.D. Srikakulam (A.P) continued on page 23........ LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 22 LYNX TESTIMONIALS continued from page 22........ DERMATOLOGY "I have been using Lynx both in Adults & children for the past 15 years in more than 5000 patients. Overall compliance and efficacy of Lincomycin is excellent. No resistance has been observed in any of the patients. Adverse side effects : A small percentage of patients had GI disturbances. These side effects are reversible once the drug is withdrawn. Tolerance: Good." Dr.G. Raghu Rama Rao M.D. (Derm.) Visakhapatanam "We have been using your skin range products since many years. Especially LYNX Capsules (Lincomycin) being exclusively used by us for many Dermatological conditions in more than a thousand patients. We are extremely satisfied with results in following conditions: 1. Recurrent pyodermas 2. Carbuncles 3. Recurrent infected Eczemas 4. Hidradenitis suppurativa 5. Chronic Non-Healing ulcers 6. Bacterial infections in HIV patients 7. Acne vulgaris (Pustular variety) We use Cap. Lynx 500 mg 1BD/1TDS. For 5-7 days accordingly." Dr. Amit Shah & Dr. Bharat C. Shah M.B.B.S., D.V.D., D.N.B., M.B.B.S., D.D.V., M.I.C.A.I, Sangli Sangli Also Endorsed by: Dr. Abdul Latif Iqbal, Warangal. Dr. Yaramati Satyanarayana, Kakinada-533001. Dr. Esufi, Godhra. Dr.P Guru Prasad, Visakhapatnam-530 016. Dr. D.Biswas, Sadar Hospital. Dr. B V Satyanarayana, Visakhapatnam-530002. Dr. Gautam Gupta, Sardar Hospital. Dr. Nihar Ranjan Bhattacharyya, North 24 Parganas. Dr. PK Sen, Khanakal. Dr. N Marappa, Bangalore-50. Dr. Antaryami Sahu, Orissa. Dr. Devaraj, Kolar. Dr. BD Jena, Bhubaneshwar. Dr. Juzer Hussain, Ujjain, M. P. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 23 LYNX TESTIMONIALS E.N.T. "I am using injection Lynx Post operatively after mastoid surgery and Tympanoplasty since last 5-7 years. It gives good results especially in cholesteotoma (mastoid) surgery." Dr. N.D.Jogani M.S. (E.N.T.) Ahmedabad " Lynx 500 TID x 10 days Gives excellent result in Acute Otitis Media, Acute Otitis Externa, Acute URTI, Acute tonsillitis. I am using this drug since last 20 years." Dr. K.N. Pansara M.S.(E.NT.) Jamnagar " Indications for prescribing Lynx - Salivary gland swelling - Recurrent Tonsilitis - Peritonsillar Abscess - Acute Maxillary sinusitis I prefer to write above drug due to very good tissue penetration, no resistance & excellent compliance." Dr. Jayesh Patel (E.N.T.) Rajkot "I have been using Lynx Injection and capsules for the last so many years to my fullest satisfaction. It is very convenient and effective against plethora of microbes." Dr. Jyoti Prakash Gupta M.S.D.L.O., Jammu "As a senior ENT consultant I used your Lynx Injection & Lynx Cap. in - Chronic Suppurative Otitis Media - Acute Follicular tonsillitis - Maxillary sinusitis - Neck Swelling since 8 years. I am happy and getting good results in Injectable form because of once a day dose." Dr. Shailen B. Mody M.S.(E.N.T.)D.L.O., Ahmedabad Also Endorsed by: Dr. Rajiv Jha, Ahmedabad. Dr. Mohammed Lateef, Srinagar. Dr. Hitesh Shah, Ahmedabad-380 008. Dr. Bilal Ahmad Raja, Basant Bagh. Dr. Nigam, Raipur. Dr. P Koteswara Rao, MBBS, MS, ENT. Dr. Dilip Majumdar, Berhampore General Hospital. Dr. GSN Murthy, Kakinada-533003. Dr. Vikram Oak, Pune. Dr. B Kotilinga Murthy, Visakhapatnam - 7. Dr. Vijay Ketkar, Pune. Prof (Dr.) A M Saha, Kolkata-700016. Dr. Tamhare, Pune. Dr. M A Kirne, Shrirampur. Dr. Girish Rajharkut, Sholapur. Dr. H S Satish, Bangalore - 560010. Dr. Himanshu J Thakkar, Rajkot - 360 004. Dr. Rajesh Gupta, Ramnagar. Dr. Pankaj Shah, Bhavnagar. Dr. Pankaj Arora, Mohali Ph:2261900. Dr. Shivanand Jha, Bhavnagar. Dr. Shrenik K Shah, Rajkot. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 24 LYNX TESTIMONIALS DENTAL "I am using Lynx Injections & capsules in my practice for last 15 years. It has always remained a drug of choice in my practice for moderate to severe oral- dental infections. The product is quite affordable to all the categories of patients. It is also available at every corner. Wallace Pharma has done a commendable job by getting this product for the service of ailing mankind. I convey my best wishes to this house for endeavors of similar nature." Dr. R. P. Abrol B.D.S.(Bomb)M.I.A.I.D. Jammu "Using Lynx Injection from so many years with faith and trust. Using in Periapical abscess indication and got satisfactory results from Lynx (Positive ++)." Dr.Vinay Gupta, BDS(DVG) Dental surgeon Udhampur "I am using Lynx since last 16 years in my dental practice. I am using it in dental root abscess and I am getting very goods result as it is economical and convenient in single dose per day to the patients. I wish every practitioner will get some benefit from this as antibiotic in day to day practice." Dr. A. K. Srivastava B.D.S. (Pat), dental surgeon Darbhanga "Lynx (Lincomycin) is a spectrum antibiotic which covers almost entire range of micro organism either it be Gram+ve or anaerobes. I have been prescribing LYNX for the last 5 years and got some tremendous results in the cases like Ludwig's Angina, Cellulitis, Periradicular Abscess and any deep seated soft tissue infections. Apart from that it has some good role in the Gingival Diseases also. So, I think LYNX is the best use antibiotic now a days with least side effects." Dr. A. K. Singh B.D.S. New Delhi "Injection Lynx is used for severe extra oral swelling with Periapical infection of all types dental and osteolytic infection like Ostemyelitils, Cellulitis, Ludwig's Angina, Supramandibular, Submental, Canine space infection. The result is also very prompt and excellent in cases of severe acute, chronic, and recurrent Pericoronitis with severe trismus. I am using Lynx Injection since my internee work job from 1993 onwards. Now in my hospital job and private practice all types of serious cases my 1 st drug of choice is Injection Lynx." Dr. Raibata Gangopadhyay BDS (Cal), Gold Medalist Durgapur LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 25 LYNX TESTIMONIALS DENTAL Also Endorsed by: Dr. M B Halkati, Bagalkot. Dr. A V Khimani, Veraval - 362266. Dr. Ashutosh Nirola, Patiala. Dr. Sajjad Qadir, Hyderpora. Dr. Ch. V R Nageswara Rao, Khammam - 507 001. Dr. Mohammad Ayub, Srinagar. Dr. P Venkateswar Rao, Khammam. Dr. Mohmad Shafi Hakim, Rajouri Kadal Chowk. Dr. Potu Vinod, New Paloncha-507115. Dr. Abdul Wahid Malik, Srinagar. Dr. Rajani Kanth Pulluri, Warangal - 506002. Dr. (Mrs)Veena Chaudhry, Chandigarh. Dr. S K Jha, Laheriasarai. Dr. T J Chiang, Vizianagaram. Dr. CK Jaiswal, Katni. Dr. Kurshid Ahmed, Jamui. Dr. SK Agarwal, Jhansi. Dr. Maslahuddin Khan, Kolar - 563101. Dr. Sakina Jinwala, Godhra. Dr. Sanjay Mohanchandra, Bangalore - 78. Dr. NC Maity, BDS. Dr. Ashish Y Thakore, Mangrol - 362225. Dr. Puneet Mehta, Bharaich. Dr. Ziauddin Ahmad, Aligarh. Dr. LD Gupta, Indore. Dr. R. D. Rajan, Dindigul - 1. We will be very pleased to receive your feedback. Please send your Queries/Comments/Suggestions to : Medical Advisor, Flora Deck Plaza, Off Central MIDC Road, Andheri (E), Mumbai-400 093. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 26 CLINICAL ADVANTAGES OF LYNX + Highly effective against staphylococci, streptococci, pneumococci and anaerobes. + No cross allergenicity with the penicillins or cephalosporins. + Readily penetrates all body tissues including bone in therapeutic concentrations. + Remains active in the presence of bacterial enzymes, pus and necrotic tissue. + Enhances host defense functions. + Available in a full range of dosage forms: oral, intramuscular and intravenous. + Advantage of once daily intramuscular injection which is virtually pain free. + Wide range of therapeutic use. + Backed by outstanding clinical success. LY N X T H E A N T I B I O T I C T H AT P E N E T R AT E S & W O R K S 27 Infections seen in daily practice Tonsillitis/Pharyngitis Dental Infections Bone & Joint Infections Soft Tissue Infections LYNX The First Choice Antibiotic (Lincomycin) For Best Results Start with Stay with LYNX LYNX I.M. INJECTION CAPSULES & SYRUP Flora Deck Plaza, Off Central MIDC Road, Andheri (E), Mumbai-400 093. www.wallacepharma.net Trade Mark Acute PID The Polymicrobial Problem LYNX (Lincomycin HCl - I.M.) plus Amikacin Attacks anaerobes Attacks G-ve aerobes Assures 97% success Start with LYNX I.M. bid Stay with LYNX capsules tid Flora Deck Plaza, Off Central MIDC Road, Andheri (E), Mumbai-400 093. www.wallacepharma.co.in Trade Mark PRESCRIBING INFORMATION COMPOSITION LYNX CAPSULES Each capsule contain Lincomycin Hydrochloride I.P. equivalent to Lincomycin base.........250 mg. Each capsule contain Lincomycin Hydrochloride I.P. equivalent to Lincomycin base.........500 mg. LYNX SYRUP Each 5 ml contain Lincomycin Hydrochloride I.P. equivalent to Lincomycin base...............125 mg. LYNX INJECTION Each ml contain Lincomycin Hydrochloride I.P. equivalent to Lincomycin base..................300 mg. INDICATIONS Lynx is effective in the treatment of infections of the Upper Respiratory Tract, Lower Respiratory Tract, Skin and Soft Tissue, Bone and Joints; and Otitis Media caused by Staphylococci (including penicillinase producing strains), Streptococci, Pneumococci and susceptible anaerobes. Lynx is also effective in Septicaemia and Endocarditis caused by above organisms. Lynx has been demonstrated to be effective in anaerobic wound, soft tissue, pulmonary and bacteraemic infections. The anaerobic spectrum of activity includes Clostridium tetani, Clostridium perfringens, Corynebacterium diptheriae, Corynebacterium acnes, Bacteroides, Fusobacterium, Peptococcus, Peptostreptococcus and Actinomyces. DOSAGE AND ADMINISTRATION Lynx Capsules/Syrup and Lynx Injection: Oral* Intramuscular Intravenous Adults: Mild to moderately 500 mg t.i.d. 600 mg (2 ml) 600 mg (2 ml) to 1 gm. severe infections every 24 hours every 8 to 12 hours. Administer in an infusion of Severe infections 500 mg 600 mg (2 ml) 5% glucose in water or (or more) q.i.d. every 12 hours normal saline Children** Mild to moderately 30 mg/kg/ day in 10 mg/kg 10 to20 mg/kg/ day severe infections 3/4 equal doses every 24 hours in two or three doses at 8-12 hours intervals Severe infections 60 mg/kg/ day in 10 mg/kg Administer as infusion. 3/4 equal doses every 12 hours Dilute as for adults. Lynx Injection should not be injected IV as a bolus. * For optimal absorption, it is recommended that nothing be given by mouth except water for a period of one to two hours before and after oral administration of Lynx. ** Over one month of age All doses may be increased in more severe infections. Doses as high as 8.0 grams per day for seven days in four divided doses of 2000 mg in an infusion of 200 ml of normal saline over a period of 120 minutes were well tolerated in normal volunteers. PRESENTATION LYNX CAPSULES 250/500 mg. - Strip of 10 capsules. 5 strips in a carton. LYNX SYRUP - Bottle of 60 ml. LYNX INJECTION - Ampoules of 2 ml. and 1ml. Flora Deck Plaza, Off Central MIDC Road, Andheri (E), Mumbai-400 093. www.wallacepharma.net Trade Mark
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text:
May 15-17 - Psycho California
June 6 - The Rolling Stones
June 10 - Melvins
June 20 - Blur
June 24-28 - Glastonbury
July 18 - Death Grips?
July 26 - Faith No More
September 25 - Kraftwerk
Happy birthday, Tom and Stephen Sondheim!
2015 Collaborative Playlist on Spotify.
Aren't you dead yet? Congrats on another year of survival.
northside groove...southside groove....eastside groove...westside groove
Paul Simon.
Fans of TheLastGreatMan Accessory Shop
Happy gofuckyourself!
Happy Birthday! Love you tons!
hey thanks everybody.
bryan i haven't quite figured out how this works.
Happy birthday Tom!
5/15 - Muse - Mayan
5/23 - Ceremony - Echoplex (?)
5/26 - Refused - Roxy
5/27 - Neutral Milk Hotel - Warner Grand (?)
5/30 - Spoon - Wiltern (?)
last.fm, if you care
Twitter, if you dare
Tom, i hope you felt this awesome all day and every day:
Happy Birthday!!!
Just, Fuck You, that's all Fuck You!
Wow, 12 step meetings at Coachella, who knew? SOBERCHELLA.COM
I'm a reasonable male, get off my case....
Happy birthday, "Daddy"!! Cheers.
seemed like the only appropriate response for this thread
Whiskey Sour
2 oz blended whiskey
Juice of 1/2 lemon
1/2 tsp powdered sugar
1 cherry
1/2 slice lemon
Shake blended whiskey, juice of lemon, and powdered sugar with ice and strain into a whiskey sour glass. Decorate with the half-slice of lemon, top with the cherry, and serve.

subset: commoncrawl


text:
While waiting for sentencing, to be held July 24, Monsignor William Lynn will cool his heels in a jail cell.
The first highly placed Catholic official convicted in a sex-abuse case will stay in jail while he awaits sentencing, which was moved up to July 24. Common Pleas Court Judge M. Teresa Sarmina on Thursday rejected a request to allow Monsignor William Lynn to live under house arrest in the Lower Northeast home of Rita DeCarolis, an elderly in-law's in-law. The judge also moved up Lynn's sentencing date, which was originally set for Aug. 13. On June 22, a jury found the 61- year-old monsignor guilty of one count of endangering children. He immediately was taken into custody and has been held in the Curran-Fromhold Correctional Facility on State Road. Prosecutors have said they will ask for the maximum sentence of seven years and added they viewed Lynn as a flight risk. Lynn faces from three and a half years to seven years imprisonment. Lynn's attorneys said they planned to appeal the conviction once Sarmina sentences their client.
— Convicted felon Monsignor William Lynn hopes for a taste of freedom before he is sentenced.
Monsignor William Lynn charged on one count of endangering children. Jury deadlocked on verdict for Rev. James Brennan.
The jury in the priest sex abuse trial in Philadelphia sent a note to the judge this morning telling her that it had reached one verdict, but was a hung jury on all other charges.
The Philadelphia Roman Catholic Archdiocese has paid $11.6 million in legal costs in the past two years, mostly stemming from a grand jury report on sexual misconduct by clergy members.


text:
Appeals court stops hearing in Texas arson case
AUSTIN, Texas A state appeals court halted a hearing Thursday that was to determine whether Texas wrongfully executed a man based on faulty arson evidence.
The court granted an emergency stay and ordered District Judge Charlie Baird not to rule on the case. The order gives Innocence Project lawyers seeking to clear Cameron Todd Willingham's name until Oct. 22 to respond.
Willingham was executed in 2004 after being convicted of setting fire to his Corsicana home, killing his three daughters. If he is exonerated, it would mark the first time an official in the nation's most active death penalty state has formally declared that someone was wrongfully executed.
Navarro County District Attorney R. Lowell Thompson, whose office convicted Willingham in 1992, sought the stay after Baird declined to recuse himself. Thompson has questioned Baird's impartiality, noting he received an award this year from the Texas Coalition to Abolish the Death Penalty.
Thompson said he was pleased with the order.
"I don't mean any disrespect to the judge, but I am going to follow procedures," Thompson said.
Innocence Project co-founder Barry Scheck said he is confident the stay will be lifted next week, permitting Baird to issue a ruling on Willingham's guilt or innocence.
"We have great law on our side," Scheck said.
The appeals court order came at the end of an afternoon of testimony in which two fire experts said the blaze that killed Willingham's three daughters was an accident, not arson.
Florida-based fire expert John Lentini ridiculed the findings and testimony of a deputy fire marshal who concluded Willingham set the house fire that killed his 2-year-old daughter and 1-year-old twins. That fire marshal, Manuel Vasquez, has since died.
"The bottom line is all of the evidence is consistent with an accidental fire," Lentini said.
The State Fire Marshal's Office continues to stand behind the arson finding.
Lentini referred to Vasquez as "misinformed" and "totally off the wall" and said his conclusions were "completely without merit, completely unreliable."
Later, Baird seemed to hint at which way he was leaning when he asked fire expert Gerald Hurst, "If we can say it wasn't arson, can we say what it was?"
Hurst replied that he believed the fire was an accident, probably caused by faulty wiring.
San Antonio lawyer Gerry Goldstein also presented evidence that a jailhouse snitch who testified in the original trial that Willingham had confessed later changed his story. Goldstein presented an affidavit showing the informant had recanted. That affidavit had never been part of the case file.
Their testimony was not challenged by anyone because Thompson had left to seek the stay.
Eugenia Willingham, the stepmother of the executed man, told reporters she was grateful for the chance to present new evidence in court.
"I just don't think there are words," she said, her eyes welling.
The hearing was part of an unusual court of inquiry hearing that was granted by Baird, who began the proceeding by declining to recuse himself.
John Bradley, a district attorney who chairs the Texas Forensic Science Commission that is looking into whether fire investigators in the case committed professional misconduct, blasted Baird's decision in an e-mail to The Associated Press.


text:
Home / All Posts
TheLaughButton 14 hrs ago feedproxy.google.com
Well this news bums us out. Paul F. Tompkins has announced that he's ending his excellent interview webseries Speakeasy. Tompkins kicked off the Made Man interview series in 2012 with Ty Burrell conducting in-depth with comedian friends and interesting entertainers over some drinks at a bar. T... [Read More]
Watch Brian McElhaney and Nick Kocher Play Joseph Gordon-Levitt and Anne Hathaway's Superhero Sidekicks
SplitSider 18 hrs ago splitsider.com
Here's a new sketch from Joseph Gordon-Levitt's Pivot series Hit Record on TV written and directed by BriTANicK's Brian McElhaney and Nick Kocher, who also star alongside Gordon-Levitt and Anne Hathaway as two less-than-respected superhero sidekicks who dream of getting promoted ou... [Read More]
TheLaughButton 19 hrs ago feedproxy.google.com
PURCHASE: Amazon | iTunes At the top of the year comedian and actor Taylor Negron passed away from liver cancer at the age of 57. While that news is crushing in and of itself, Negron was always "that guy from that thing." Appearing in movies like Fast Times At Ridgemont High and The Last... [Read More]
TheLaughButton 19 hrs ago feedproxy.google.com
An audience member at a town hall meeting experiences an awkward case of mistaken identity in this preview sketch for the upcoming season of Key & Peele returning to Comedy Central July 8. We can't wait for season 5! Watch this preview sketch from the fifth season of "Key & Peele... [Read More]
SplitSider 19 hrs ago splitsider.com
It's a sad day for people who like great interviews with great actors and comedians. Paul F. Tompkins announced in a Tumblr post today that he's decided to end his web series Speakeasy, which he's hosted since 2012, to focus on other projects: In an effort to devote more time, ener... [Read More]
TheLaughButton 20 hrs ago feedproxy.google.com
Here's your first look at Difficult People starring Julie Klausner (Bob's Burgers) and Billy Eichner (Billy on the Street). The story revolves around best friends living in New York City with their behavior landing them in awkward situations. Watch the trailer here: Here's your fir... [Read More]
SplitSider 20 hrs ago splitsider.com
From jet skiing from Chicago to New Orleans to orchestrating skywriting pranks, comedian Kurt Braunohler is always someone we can count on to bring a little absurdity into our lives. Thankfully, Braunohler kicks off a brand new venture today that might be his weirdest project yet: driving a giant bu... [Read More]
SplitSider 21 hrs ago splitsider.com
Are you in the mood for a bit-off? Because that's apparently what happened recently between comedians Zach Broussard and Rich Vos on a recent episode of the Legion of Skanks podcast, which started when Vos discovered Broussard's joke list "Top 1000 Comedians of 2014." Alongsi... [Read More]
SplitSider 21 hrs ago splitsider.com
'Genie in a Bottle' is a recurring feature where each week a different bottle episode (an episode set entirely in one location, often designed to save money) from a comedy series is examined "Today lunch, tomorrow the world." Bewitched is a classic sitcom telling an age-old s... [Read More]
SplitSider 22 hrs ago splitsider.com
Here's a brand new sketch from Inside Amy Schumer that tackles the age-old question of whether it's the right time to move in with a boyfriend, except in this case things get way more complicated when multiple time-traveling Amy Schumers are thrown into the mix. Ultimately, what matters ... [Read More]


text:
Dinah and the Shechemites
Dinah and the Shechemites
1 Now Dinah, the daughter Leah had borne to Jacob, went out to visit the women of the land.
2 When Shechem son of Hamor the Hivite, the ruler of that area, saw her, he took her and raped her.
3 His heart was drawn to Dinah daughter of Jacob; he loved the young woman and spoke tenderly to her.
4 And Shechem said to his father Hamor, "Get me this girl as my wife."
5 When Jacob heard that his daughter Dinah had been defiled, his sons were in the fields with his livestock; so he did nothing about it until they came home.
30 Then Jacob said to Simeon and Levi, "You have brought trouble on me by making me obnoxious to the Canaanites and Perizzites, the people living in this land. We are few in number, and if they join forces against me and attack me, I and my household will be destroyed."
31 But they replied, "Should he have treated our sister like a prostitute?"
24 All the men who went out of the city gate agreed with Hamor and his son Shechem, and every male in the city was circumcised.
25 Three days later, while all of them were still in pain, two of Jacob's sons, Simeon and Levi, Dinah's brothers, took their swords and attacked the unsuspecting city, killing every male.
26 They put Hamor and his son Shechem to the sword and took Dinah from Shechem's house and left.
27 The sons of Jacob came upon the dead bodies and looted the city where[a] their sister had been defiled.
28 They seized their flocks and herds and donkeys and everything else of theirs in the city and out in the fields.
29 They carried off all their wealth and all their women and children, taking as plunder everything in the houses.
18 Their proposal seemed good to Hamor and his son Shechem.
19 The young man, who was the most honored of all his father's family, lost no time in doing what they said, because he was delighted with Jacob's daughter.
20 So Hamor and his son Shechem went to the gate of their city to speak to the men of their city.
21 "These men are friendly toward us," they said. "Let them live in our land and trade in it; the land has plenty of room for them. We can marry their daughters and they can marry ours.
22 But the men will agree to live with us as one people only on the condition that our males be circumcised, as they themselves are.
23 Won't their livestock, their property and all their other animals become ours? So let us agree to their terms, and they will settle among us."
12 Make the price for the bride and the gift I am to bring as great as you like, and I'll pay whatever you ask me. Only give me the young woman as my wife."
13 Because their sister Dinah had been defiled, Jacob's sons replied deceitfully as they spoke to Shechem and his father Hamor.
14 They said to them, "We can't do such a thing; we can't give our sister to a man who is not circumcised. That would be a disgrace to us.
15 We will enter into an agreement with you on one condition only: that you become like us by circumcising all your males.
16 Then we will give you our daughters and take your daughters for ourselves. We'll settle among you and become one people with you.
17 But if you will not agree to be circumcised, we'll take our sister and go."
6 Then Shechem's father Hamor went out to talk with Jacob.
7 Meanwhile, Jacob's sons had come in from the fields as soon as they heard what had happened. They were shocked and furious, because Shechem had done an outrageous thing in[b] Israel by sleeping with Jacob's daughter—a thing that should not be done.
8 But Hamor said to them, "My son Shechem has his heart set on your daughter. Please give her to him as his wife.
9 Intermarry with us; give us your daughters and take our daughters for yourselves.
10 You can settle among us; the land is open to you. Live in it, trade[c] in it, and acquire property in it."
11 Then Shechem said to Dinah's father and brothers, "Let me find favor in your eyes, and I will give you whatever you ask.
Top 10 sermons on Genesis 34
- A Fathers Blessing
- Culture Shift: Casualties of War
- Weathering the Storms in Life
- Hitting Bottom
- God's kind of love
Copyright © 1973, 1978, 1984, 2011 by Biblica, Inc.®
Used by Permission of Biblica, Inc.® All rights reserved worldwide.


text:
Hull City v Manchester United, 12.45pm
Hull manager Steve Bruce could name an unchanged line-up for a fourth game in a row, but Danny Welbeck is a doubt for United, who are also likely to be without Michael Carrick and Robin van Persie. Read full Hull v Manchester United preview.
Aston Villa v Crystal Palace
Villa welcome back Gabriel Agbonlahor from suspension but are without Ashley Westwood, who serves his own ban, and almost certainly Christian Benteke and Ron Vlaar.
Palace, meanwhile, are without the suspended Marouane Chamakh and have a host of injury worries. Read full Aston Villa v Crystal Palace preview.
Cardiff City v Southampton
Craig Bellamy remains the only injury concern for Cardiff, while Southampton's injury worries are also easing up with Dani Osvaldo, Luke Shaw, Nathaniel Clyne and Kelvin Davis in line for returns to the squad on Boxing Day. Read full Cardiff v Southampton preview.
Chelsea v Swansea City
Chelsea boss Jose Mourinho is set to rotate his squad ahead of the game against Liverpool at the weekend, while Swansea remain without Michu, Michel Vorm and Nathan Dyer. Read full Chelsea v Swansea preview.
Everton v Sunderland
Leighton Baines could return to the Everton squad, as could Nikica Jelavic, while Sunderland are without the suspended Wes Brown and are sweating on the fitness of John O'Shea. Read full Everton v Sunderland preview.
Newcastle United v Stoke City
Hatem Ben Arfa could return for Newcastle in the absence of the suspended Cheick Tiote, while Stoke have Stephen Ireland available again but may decide to start with Charlie Adam after he scored at the weekend. Read full Newcastle v Stoke preview.
Norwich City v Fulham
Norwich have a doubt over Jonny Howson but could welcome back Russell Martin, while Fulham have doubts over Dimitar Berbatov, Philippe Senderos, Brede Hangeland and Matthew Briggs, and are definitely without Hugo Rodallega. Read full Norwich v Fulham preview.
Tottenham Hotspur v West Bromwich Albion
Aaron Lennon has been added to Spurs' injury list ahead of the game, joining the likes of Andros Townsend and Jan Vertonghen on the sidelines, but Mousa Dembele should be fit.
Victor Anichebe, meanwhile, is the only injury concern for West Brom. Read full Tottenham v West Brom preview.
West Ham United v Arsenal
West Ham have Kevin Nolan available again but remain without several other players, while Arsenal could welcome back Laurent Koscielny but are again shorn of the services of the suspended Jack Wilshere. Read full West Ham v Arsenal preview.
Manchester City v Liverpool (5.30pm)
City remain without Pablo Zabaleta, Micah Richards, Sergio Aguero and Matija Nastasic, with Stevan Jovetic again a doubt, while Steven Gerrard, Daniel Sturridge, Jose Enrique and Sebastien Coates are absentees for Liverpool. Read full Manchester City v Liverpool preview.


text:
This is a good trade if Lopez can be the leadoff hitter we have been looking for. Bowden needs to get a #1 starter with the extra money he has now.
This is a good trade if Lopez can be the leadoff hitter we have been looking for. Bowden needs to get a #1 starter with the extra money he has now.
I don't know about Lopez speed, but I think we may be putting him in the starting line up fast. I think he has to earn it over the likes of Larson or some other move like Larkin to 2B, Boone to SS, Branyan, Larson 3B. We will see. If we get no other pitching this deal stinks IMO, but I hope I'm wrong.
And This One Belongs to the REDS!!!
I like the trade.
We get our SS of the future, and unload Dessens.
Despite his 2002 numbers, Dessens IS NOT a guy who I consider a #1 or #2 starter. I think he had a career year in 2002, and would have receive too much in arbitration to warrant keeping. I agree with Rob Neyer. Dessens would not come close to repeating his 2002 numbers.
What I really wish is that Larkin would move to 2B and let Lopez take over SS so the kid can concentrate on hitting and not learning a new position.
Two years from now, this will turn out to be a GREAT trade. I think it will be a POSITIVE trade this year.
Opinions are like belly buttons. Everybody has one, and they don't want someone else's shoved into their face.
Didn't know if this has been added yet.
"Also, Oakland, Toronto and Cincinnati each sent $333,333 to Arizona."
So...it wasn't a bunch of cash.
I like this deal assuming something else is coming. Lopez is a great young prospect.
Only one things sums it up...welcome to Kansas City.
**I'm just throwing the world curve balls.**
Click here for FalconBlog
Will be won at spring training, according to the interview with Bob Boone. He also mentioned that both Lopez and Larson have option(s).
With a OBP less than .300, and 90 SO in 282 AB's, this guy is NOT a lead off hitter. He is young, but man.
If you wanted a SS that strikes out all the time, but hits a HR once a week or so, why not get Hernadez (of the Brewers) who would have come for free ( as a FA)?
"Is there a problem officers?"
Griffey 30,
What is your SN at fanhome?
Sony High Definition TV: $2000
Digitable Cabe: $50
Watching Peter Gammons "inform" on Baseball Tonight: Priceless
I have no screen name there, i was just looking around.
Seemed like somebody I know at fanhome.
Sony High Definition TV: $2000
Digitable Cabe: $50
Watching Peter Gammons "inform" on Baseball Tonight: Priceless
Classic Bowden of trading players that have reached their all-time highs for players that have high ceilings. We seen it before with Konerko going to the White Sox for Cameron.
Lopez is going to be a gem of a shortstop. You heard it hear from the ole Kruster. I doubt very much Walker and Dessens could improve much more than what they did this past season. Next up to be moved will be Gabe White.
Reds have cleared almost 7 million in payroll to make a trade for a frontline pitcher or possibly sign two B-type free agent pitchers.
People ***** and moan about trading Dessens. But really, is he anything better than a number 3 starter? Lopez might be the next Tejada. If a guy's projected ceiling is at the level, then you make the deal and take the money saved and play the free agent market for a pitcher.
I already mentioned this in a different thread, but this is some food for thought...
Lopez was rated higher than both Dunn and Kearns entering the 2001 season.
Sony High Definition TV: $2000
Digitable Cabe: $50
Watching Peter Gammons "inform" on Baseball Tonight: Priceless
Can you imagine if he does become the next Tejeda? Heck, I would be happy if he could just fill Larkin's shoes.
Not only a great trade for the present and future, but the precursor to what appears to be even more imminent improvements.
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Veterans Memorial of Orange Park, Florida
Veterans Day Ceremony Essay Contest
The Historical Society of Orange Park and the Town of Orange Park hosted the Annual Veterans Day Ceremony on Tuesday, November 11th at the Veterans Memorial in Historic Magnolia Cemetery. The ceremony included the presentation of the winning essays in our Annual Veterans Day Essay Contest.
Following are the students that submitted the winning essays:
Elementary - "What is Veterans Day?"
Melissa Mora, S. Bryan Jennings Elementary
Click here to read Meslissa's essay.
Junior High - "Why do veterans deserve our support, respect and understanding?"
Hailey Smith, Oakleaf Junior High
Click here to read Hailey's essay.
Senior High - "Why do you think it is important to celebrate Veterans Day?"
Hannah Madeline Clark, Clark Christian Academy
Click here to read Hannah's essay.
Purchase a Memorial Brick Paver
You still have an opportunity to honor the Veteran(s) in your life through this important community project by purchasing an inscribed memorial brick paver that will be installed around the memorial.
Pavers (4"x8") $50
Download the Memorial Brick Paver form and mail it with your payment to the Historical Society of Orange Park, P.O. Box 08, Orange Park, FL 32067. Please make your check payable to Historical Society of Orange Park. All proceeds will go toward the new Veterans Memorial.
Download a donation form and mail your contribution to the Historical Society of Orange Park, P.O. Box 08, Orange Park, FL 32067. The Historical Society of Orange Park is a non-profit, 501(c)(3) corporation.
For more details contact Carolyn Ann Day 215-9177 or firstname.lastname@example.com. All proceeds will go toward the new Veterans Memorial.


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Man Steals Tons of Cheese and Then Flees to New Jersey
You can't blame the guy for liking his cheese, all 42,000 pounds of it!
You can't blame the guy for liking his cheese, all 42,000 pounds of it!
Pushy person gets punched......more at 11.
You may not know 56-year-old Peter Robbins, but chances are you know his voice....
"I just robbed a bank. Now I can finally pay for college, and a new car! By the way, I love Green Day."
Another classic story of the unexpected and stupid comes from Toms River!
Everybody knows that I-295 is a real danger due to the overwhelming amount of elephants...
As I was leaving the Irish Pub in Atlantic City Saturday night, I witnessed one of the oddest moments ever.
Principal Tyler Blackmore recently told middle school students at Matawan-Aberdeen Middle School in Asbury Park, that they were in a "no hugging school". What, no hugging? So, what happened next?
The name of the next President of Rutgers University has been a closely guarded secret. Until the cat got out of the bag a little too early.
In Wisconsin, 19-year-old Alexander Hart has been arrested for disorderly conduct after he was photographed "planking" on a police car and on a police memorial to seven dead officers.


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Select Local Merchants
Xtreme Polishing SystemsRead MoreXtreme Polishing Systems invites you to join us at our warehouse to receive personal on-the-spot training with real equipment and tools. Join us at any of our seminars during the year and network with other contractors and manufacturing representatives. Also ask about our concrete polishing business packages, which has been developed through years of research and over 15 years of industry experience. Looking for full service concrete flooring solutions? National Concrete Polishing, our sister company, offers industrial, commercial and residential flooring installations in the state of Florida and New Jersey. Polished concrete is the most cutting-edge and cost-effective flooring solution today! Our Earth-friendly systems eliminate toxic or hazardous chemicals and ensures that your families, business and employees are always protected. For more info please email email@example.com NW 32nd Street Suite 700Deerfield Beach, FL US
Jerry's Artarama Fort LauderdaleRead MoreSince 1968, Jerry's Artarama has stocked shelves with multitudes of tools and supplies and helped artists show off finished work with custom framing. The comprehensive inventory fulfills artists' every need, featuring everything from acid-free blank stretched canvases to Lukas oil colors, which have been transmitting images to paper since 1862. Custom framing services can protect and showcase a diploma, favorite 8"x10," or beloved box of cereal.242 S Federal HwyDeerfield Beach, FL US
Bentley RoofingRead MoreWhen it's raining inside the house, it's time to call on Bentley Roofing. And maybe even before this happens. A roofing specialist guides the client through each process, and even shares a cell-phone number and email address so that they are available at all times to address an issue. Crews arrive onsite and dutifully repairs roofs, whether they're made of shingles, tile, metal, or Lincoln Logs. When the roof is so bad that it needs to be torn off, the team quickly replaces it with high-quality, long-lasting materials.1121 South Military TrailDeerfield Beach, FL US
CleanKing Carpet/Tile CleaningRead MoreCleanKing's technicians scour carpets and clean tile with green-certified products that are nontoxic and biodegradable. For more than 25 years, they've achieved optimal results that are safe for the whole family. The techs also apply their expertise to upholstery and area-rug cleaning, protect carpets with 3M Scotchguard, and and fortify tiled surfaces with sealers.3840 w. Hillsboro #140Deerfield Beach, FL US
Covenant PoolsRead MoreThe licensed technicians at Covenant Pools expertly repair and clean residential pools and related equipment, helping to maintain safe outdoor environments for entertaining, lap swimming, or manatee sleepovers. Visits from the trained team can take place on a daily, weekly, monthly basis if desired, or they can be scheduled as needed.682 nw 44th ter #101Deerfield Beach, FL US
Rack Lighting and Electrical ContractingRead MoreThe silent church seems to lean in with anticipation as Dr. Karen Kennedy raises her arm into the air. With a graceful flick of her baton, the artistic director of Master Chorale of South Florida—an accomplished conductor and teacher—coaxes forth the opening strains of Bach's Magnificat from the flock of singers and musicians in front of her, weaving their voices into a tapestry of crescendos and soaring notes. Since its creation in 2002, Master Chorale of South Florida has performed their awe-inspiring concerts in churches, cathedrals, and high schools across South Florida, delighting audiences with a diverse choral repertoire. Audiences can expect to hear many musical periods represented in each performance, from the baroque stylings of Handel to Debussy's impressionistic melodies and Aaron Copland's epic pieces that blend traditional American folk songs with traditional Bruce Springsteen hits.3601 N Dixie HwyBoca Raton, FL US


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Do you think some people are more liberal in their use of the ER, and why?
ER use/abuse
Do you think some people are more liberal in their use of the ER, and why?
Ain't No Shame In My Game
One wonderful baby, and one on the way.
Five that I know about. Maybe more.
My daughter has been twice and both times she's been completely fine. I'm a terrible first time mom but I do have to pay for ER visits.
Old member, same account.
Sam: mom and Hep B positive. Guess which defines me better.
Clearly a Hufflepuff.
Mom to Angelina (11) - Dx'd w/ T1D March 2013
Are we on Cops again?
Once, and I went in kicking in screaming. I had a kidney stone that was blocking my ureter and causing my kidney to swell. Sometimes when I read some of the posts on BBC about people going to the ER, I am amazed at how liberal some are with the use of their services. A lot of people treat the ER like an urgent care center or a doctor's office.
Never go with a hippie to a second location
I have been to the ER only once in my entire life. It was a freak accident kind of thing. Unfortuantely my student health insurance had just expired a month earlier and my new job wasn't starting for another couple of weeks so I had no insurance. It was also after hours or I would probably have tried a local clinic first. I have been to an urgent care clinic twice.
DD: Emmaline, 2011
DS: Henry, 2014
*~* Jessie *~*
Noah - 3yr old stubborn boy
Tanner is here! 4-15-2013
"Changing the world, one little heartbeat at a time"
Four that I can remember. For my children - none at all yet.
I try to use urgent care whenever possible and the doctor rather than urgent care.
Including with my kid? 5 times.
You think ERs get abused in the US? Try coming up to Canada, it's pathetic. Anyone who doesn't have a regular GP will often show up at the ER with anything from a nosebleed to a hangnail. Obviously they triage the patients, but it still adds to the wait.
And children's ERs are the worrrrsssst. Don't even get me started.
Who is this Rorschach guy, and why did he paint all those pictures of my parents fighting?