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Publications (39)72.36 Total impact
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Article: Single event-related changes in cerebral oxygenated hemoglobin using word game in schizophrenia[Show abstract] [Hide abstract]
ABSTRACT: Neuroimaging studies have been conducted using word generation tasks and have shown greater hypofrontality in patients with schizophrenia compared with healthy subjects. In this study, we compared the characteristics of oxygenated hemoglobin changes involved in both phonological and categorical verbal fluency between 35 outpatients with schizophrenia and 35 healthy subjects during a Japanese "shiritori" task using single-event-related near-infrared spectroscopy. During this task, the schizophrenic patients showed significantly smaller activation in the prefrontal cortex area than the controls. In addition, a significant positive correlation was obtained between oxygenated hemoglobin changes (prefrontal cortex area, inferior parietal area) and the severity of positive psychiatric symptoms. It is possible that hypofrontality of patients may be a diagnostic assistance tool for schizophrenia, and that the relationship between activation and positive syndrome scores may be of help in predicting functional outcome in patients.Neuropsychiatric Disease and Treatment 12/2014; 10:2353-60. DOI:10.2147/NDT.S73975 · 2.15 Impact Factor
Article: Evaluation of P300 components for emotion-loaded visual event-related potential in elderly subjects, including those with dementia[Show abstract] [Hide abstract]
ABSTRACT: In the present study, the P300 component of the emotion-loaded visual event related potential in response to photographs of babies' crying or smiling was measured to evaluate cognitive function in elderly subjects, including those with dementia. The subjects were 48 elderly people who consulted a memory disorder clinic. The visual event-related potential was measured using oddball tasks. Brain waves were recorded from 4 sites. We analyzed the P300 amplitude and latency. Subjects were divided into three groups (dementia with Alzheimer's disease group: AD, intermediate group: MG, healthy group: HG) based on HDS-R, MMSE scores and CDR. For all subjects, there was a significant positive correlation between P300 latency and Z-score of VSRAD for crying or smiling faces. There was a negative correlation between P300 amplitude and Z-score for crying face. MG subjects were divided into two groups (high risk: HRMG, low risk: LRMG) based on Z-scores (HRMG≧2.0). The P300 amplitude of AD was significantly smaller than that of HG, and the P300 latency of AD was significantly longer than those of other groups for crying or smiling faces. The P300 latency of HRMG was significantly longer than that of LRMG for smiling face. Furthermore, the P300 latency when for crying face was significantly shorter than that for smiling face in HG and AD. These findings suggest that analysis of P300 components of the emotion-loaded visual event-related potential may be a useful neuropsychological index for the diagnosis of AD and high-risk subjects.Psychiatry and Clinical Neurosciences 01/2014; 68(7). DOI:10.1111/pcn.12162 · 1.62 Impact Factor
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ABSTRACT: Schizophrenia has been associated with a deficit of the prefrontal cortex, which is involved in attention, executive processes, and working memory. The Trail Making Test (TMT) is administered in two parts, TMT-A and TMT-B. It is suggested that the difference in performance between part A and part B reflects executive processes. In this study, we compared the characteristics of hemodynamic changes during TMT tasks between 14 outpatients with schizophrenia and 14 age- and gender-matched healthy control subjects. Using multichannel near-infrared spectroscopy, we measured relative changes in oxygenated hemoglobin concentration, which reflects brain activity of the prefrontal cortex during this task. In both tasks, patients showed significantly smaller activation than controls and, in an assessment of executive functions, a subtraction of oxygenated hemoglobin (oxy-Hb) changes during TMT-A from those of TMT-B showed a decrease in cerebral lateralization and hypoactivity in patients. There was a significant negative correlation between oxy-Hb changes and the severity of psychiatric symptoms. These findings may characterize disease-related features, suggesting the usefulness of oxy-Hb change measurement during TMT tasks for assessing functional outcomes in schizophrenic patients.Neuropsychiatric Disease and Treatment 05/2013; 9:675-85. DOI:10.2147/NDT.S43137 · 2.15 Impact Factor
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ABSTRACT: Objective: Previous eye-tracking studies using an eye mark recorder have reported that disturbances in exploratory eye movements in adult schizophrenic patients are associated with social functioning. The current study sought to determine whether exploratory eye-movement disturbances are present in children with Asperger's syndrome (AS) compared with typically developing (TD) children. Materials/Participants: The participants were 23 children with AS and 23 age-matched TD children. We measured exploratory eye movements using an EMR-8B eye mark recorder and an exploratory eye movement-measuring device. Method: Eye movements were recorded while participants freely observed a geometric figure (free viewing task), and while they complied with the instructions of an experimenter (repeat-comparison task). We assessed eye fixation points (EFPs) and total eye scanning length (TESL) in all tasks, and measured the responsive search score (RSS) in the repeat-comparison task. Results: In the free viewing task, children with AS exhibited significantly shorter TESL compared with TD children. In the repeat-comparison task, children with AS exhibited significantly lower RSS. Autism Spectrum Screening Questionnaire scores were negatively correlated with both EFP and TESL, but not RSS. Conclusion: The current results revealed that children with AS exhibited dysfunction in exploratory eye movements. Thus, assessing exploratory eye movements in a repeat-comparison task may be useful for detecting social impairment among children with AS.Brain & development 05/2013; DOI:10.1016/j.braindev.2013.04.005 · 1.54 Impact Factor
Article: [Characteristics of single event-related cerebral hemodynamics during verbal task in emotionally charged state measured by multi-channel near-infrared spectroscopy (NIRS) in patients with schizophrenia: comparison with healthy subjects].[Show abstract] [Hide abstract]
ABSTRACT: Neared infrared spectroscopy (NIRS) is one of the recently developed methodologies which can measure cerebral blood volumes to determine the blood hemoglobin (Hb) concentration simultaneously at multiple points with marked time resolution. Monitoring the changes in the Hb concentration yields site-specific readings on blood flow and, thus, on neural activities. The aim of this study was to examine the characteristics of a single event-related oxyhemoglobin concentration [oxy-Hb] changes in patients with schizophrenia using multi-channel NIRS during a word generation task, Japanese 'Shiritori', and single-word generation task in an emotionally charged state induced by three facial expressions of "crying", "neutral", and "smiling" babies' photographs. Thirty-four patients with schizophrenia and 34 age-matched healthy controls participated in the present study after giving consent. In healthy controls, [oxy-Hb] changes when viewing the "crying" baby's photograph were significantly larger than when viewing the "smiling" baby's photograph. On the other hand, in patients with schizophrenia, [oxy-Hb] changes when viewing the "smiling" baby's photograph were significantly larger than when viewing the "crying" baby's photograph. These results suggest that cautions/execution functions in patients with schizophrenia during the single event word "Shiritori" task measured by multi-channel NIRS were impaired. It was also suggested that, in patients with schizophrenia, the affective reaction influenced by each photograph may be different from healthy controls (mismatch). Multi-channel NIRS can be a useful tool for research and clinical purposes in psychiatry.Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 01/2013; 115(8):853-62.
- Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 01/2013; 115(1):3-9.
Article: State and trait markers of emotionally charged visual event-related potentials (P300) in drug-naive schizophrenia[Show abstract] [Hide abstract]
ABSTRACT: In the present study, we investigated the changes in P3 component in the emotionally charged visual event-related potentials (ERP) in 30 drug-naïve schizophrenic patients for up to 1 year. Visual oddball event-related potential was recorded from six recording sites for crying baby or smiling baby photographs. ERP were recorded before the treatment (session 1 [S1]), after 3 months (session 2 [S2]), and after 12 months (session 3 [S3]), as well as in 30 healthy subjects. Before taking medicine, there were no significant differences in the P300 amplitude between viewing photographs of a crying and a smiling baby. The P300 amplitude was significantly larger at S2 and S3 than at S1 for a crying baby, while there was no significant difference among sessions for a smiling baby after medication. A significant difference of the P300 amplitude was only observed between S3 and healthy subjects for a smiling baby. The P300 latency only when viewing a smiling face became significantly longer at S3 than those at S1 and S2. A significant negative correlation was obtained between the P300 amplitude changes upon viewing crying faces and negative syndrome score changes at the Pz site. The P300 amplitude induced by crying-face stimuli may be a state marker and the P300 amplitude caused by smiling-face stimuli may be a trait marker during recovery in schizophrenic patients. Atypical antipsychotic medications may be useful and may recover cognitive function reflected by the emotionally charged visual P300 components in schizophrenic patients.Psychiatry and Clinical Neurosciences 06/2012; 66(4):261-9. DOI:10.1111/j.1440-1819.2012.02345.x · 1.62 Impact Factor
Article: Relationships between exploratory eye movement dysfunction and clinical symptoms in schizophrenia[Show abstract] [Hide abstract]
ABSTRACT: Many psychophysiological tests have been widely researched in the search for a biological marker of schizophrenia. The exploratory eye movement (EEM) test involves the monitoring of eye movements while subjects freely view geometric figures. Suzuki et al. (2009) performed discriminant analysis between schizophrenia and non-schizophrenia subjects using EEM test data; consequently, clinically diagnosed schizophrenia patients were identified as having schizophrenia with high probability (73.3%). The aim of the present study was to investigate the characteristics of schizophrenia patients who were identified as having schizophrenia on EEM discriminant analysis (SPDSE) or schizophrenia patients who were identified as not having schizophrenia on EEM discriminant analysis (SPDNSE). The data for the 251 schizophrenia subjects used in the previous discriminant-analytic study were analyzed, and the demographic or symptomatic characteristics of SPDSE and SPDNSE were investigated. As for the symptomatic features, a factor analysis of the Brief Psychiatric Rating Scale (BPRS) rating from the schizophrenia subjects was carried out. Five factors were found for schizophrenia symptoms: excitement/hostility; negative symptoms; depression/anxiety; positive symptoms; and disorganization. SPDSE had significantly higher factor scores for excitement/hostility, negative symptoms and disorganization than SPDNSE. Furthermore, the BPRS total score for the SPDSE was significantly higher than that for the SPDNSE. SPDSE may be a disease subtype of schizophrenia with severe symptoms related to excitement/hostility, negative symptoms and disorganization, and EEM parameters may detect this subtype. Therefore, the EEM test may be one of the contributors to the simplification of the heterogeneity of schizophrenia.Psychiatry and Clinical Neurosciences 02/2012; 66(3):187-94. DOI:10.1111/j.1440-1819.2011.02314.x · 1.62 Impact Factor
Article: Left Eye Scanning Deficit in Schizophrenia Patients under Emotional Loading Task: Comparison with Healthy Controls.[Show abstract] [Hide abstract]
ABSTRACT: The aim of the present study was to evaluate and characterize visual cognitive function and the effect of emotion in patients with schizophrenia.We recorded exploratory eye movements as biologic markers in 40 schizophrenic patients and 40 age-matched healthy controls. Total eye scanning length (TESL), total number of gaze points (TNGP), and TNGP in right (right TNGP) and left (left TNGP) visual fields on screen were calculated as subjects viewed affectively charged pictures (smiling and crying babies) with fitting sounds.TESL of patients was shorter than that of controls when viewing pictures of smiling babies while recalling pleasurable events, and significantly decreased under negative emotional loading when viewing crying babies while recalling sad events. TESL recovered to the original values after loading positive emotion again in the controls. However, TESL did not recover to the original values in schizophrenic patients. TNGP showed similar alterations in the emotional loading task. When TNGP was evaluated in left and right fields, in patients, the non-recovery of TNGP was only observed in the left side. TESL and left TNGP were negatively correlated with negative symptom scores on PANSS.Schizophrenic patients'eye movements in the left visual field screen during the emotional loading task were different from those of controls, which suggests that visual cognitive function is impaired in the right brain in schizophrenic patients. Exploratory eye movements are a useful marker of visual cognitive function, and are a useful tool to evaluate the influence of emotion in schizophrenic patients.The Kurume Medical Journal 01/2012; 59(1-2):17-24. DOI:10.2739/kurumemedj.59.17
Article: Characteristics of Cortical Activation in Schizophrenia during the Card Game "Concentration"[Show abstract] [Hide abstract]
ABSTRACT: Various functional imaging studies have demonstrated reduced lateralization of cortical activation during neurocognitive tasks in schizophrenia. -A well-known card game, "concentration" , reflects working memory (WM). We compared characteristics of hemodynamic changes in the prefrontal to temporo-parietal areas of the brain during this card game between 24 outpatients with schizophrenia and 24 age- and gender-matched healthy control subjects. Using multi-channel near-infrared spectroscopy, we measured relative changes in oxygenated hemoglobin concentration (oxy-Hb changes), which reflects brain activity during this task. Patients showed reduced lateralization in the midfrontal area, which is involved in executive functions, and in the inferior parietal area, involved in WM subcomponents. We also found a significant negative correlation between left midfrontal region oxy-Hb changes and severity of negative symptoms of schizophrenia. Our results characterized disease-related features, suggesting the usefulness of oxy-Hb change measurement during this card game for assessing functional outcome in schizophrenic patients.The Kurume Medical Journal 01/2012; 59(3.4):53-60. DOI:10.2739/kurumemedj.59.53
Article: Effects of emotionally affect adult and baby' photographs in healthy controls and schizophrenic patients evaluating by exploratory eye movements.[Show abstract] [Hide abstract]
ABSTRACT: The relationship between mother and baby is of fundamental importance in the development of cognitive function and emotion. In this study we investigated the effects of affective photographs of a mother and baby (crying or smiling faces) and other stimuli (neutral mother or baby faces) on visual cognitive function in schizophrenic patents. We recorded exploratory eye movements in 22 healthy controls and 22 age-matched schizophrenic patients. Total number of right and left field gaze points (right TNGP, left TNGP) in the visual fields were determined using an eye-mark recorder as subjects viewed affectively charged or neutral photographs (crying, smiling or neutral faces). Left TNGP for all mother photographs (crying, smiling or neutral) were significantly larger in controls than patients, and right TNGP for neutral mother photographs were significantly larger in controls than in patients. Right TNGP for photographs of smiling babies were significantly larger in controls than patients, and left TNGP for photographs of both smiling and crying babies were significantly larger in controls than patients. Within the patient group, right TNGP were significantly larger than left TNGP for all mother photographs (crying, smiling or neutral). Left TNGP for photographs of mothers and babies correlated negatively with negative symptom scores. These results suggest that exploratory eye movements when viewing emotionally laded twin stimuli such as photographs of a mother and baby are a useful marker of visual cognitive function in both healthy controls and schizophrenic patients.The Kurume Medical Journal 01/2011; 58(1):27-33. DOI:10.2739/kurumemedj.58.27
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ABSTRACT: Shiritori is a popular Japanese word chain game that resembles verbal fluency tasks used in Western countries. Recently, shiritori has been used to determine the dominant hemisphere for language and as a rehabilitation tool. However, there are few reports of neuroimaging during shiritori. We used functional magnetic resonance imaging (fMRI) to conduct a detailed study of brain activities during shiritori and observed activation not only of the left inferior frontal gyrus (including the pars opecularis, the pars triangularis and the pars orbitalis), which is a language-related area, but also of the left superior and middle frontal gyri, the right pars orbitalis (inferior frontal gyrus), and the right cerebellar hemisphere. Shiritori is a useful tool for psychological study and rehabilitation.The Kurume Medical Journal 01/2011; 57(4):109-15. DOI:10.2739/kurumemedj.57.109
Article: Changes in task-associated cerebral blood induced by role lettering: measurement by multichannel near-infrared spectroscopy.[Show abstract] [Hide abstract]
ABSTRACT: Using optical topography (near-infrared spectroscopy: NIRS), relative changes in oxidized hemoglobin (oxy-Hb) were measured before and after the introduction of Role lettering. Tasks performed during measurements included antegrade (from the subject to other persons) and retrograde (from other persons to the subject) mental imaging and writing tasks. All subjects were junior high school students. Relative changes in oxy-Hb were measured before and 3, 6, and 12 months after the start of Role lettering. The region of interest (ROI) was determined based upon the motor cortex region of hand movement and upon relative oxy-Hb changes noted before any Role lettering. For antegrade mental tasks, oxy-Hb increased significantly in right-sided ROI after 3 months; this increase persisted at 1 year. For retrograde mental tasks, oxy-Hb significantly increased bilaterally at 3 months, an effect that also persisted at 1 year. With the antegrade writing task, no significant difference was observed throughout the study; with the retrograde writing task, oxy-Hb level decreased significantly in right lateral ROI after 6 months; the decrease persisted at 1 year. The number of words produced after Role lettering increased significantly in both antegrade and retrograde writing tasks at 1 year, compared with the number before Role lettering. Role lettering thus altered mental activity, particularly in the right hemisphere. Retrograde writing tasks, similar to those employed in the actual practice of Role lettering, reduced right hemispheric function; continuation of the task enhanced performance. Role lettering studies using NIRS may provide useful psychophysiologic indices.The Kurume Medical Journal 10/2010; 57(3):51-8. DOI:10.1016/S1388-2457(10)60607-4
Article: [Development of human visual cognitive function in childhood: evaluation by exploratory eye movements to a picture of a smiling face].[Show abstract] [Hide abstract]
ABSTRACT: To evaluate the development of human visual cognitive function in childhood, we examined exploratory eye movements in 78 healthy subjects using affective pictures. We divided them into six groups, each of which comprised 14 subjects (7 boys or men, 7 girls or women) at the indicated ages. Exploratory eye movements were recorded via gazing points using an eye-mark recorder. The total eye scanning length (TESL) of gaze points increased significantly with age, and the mean eye scanning length, in 4-6-year-olds was significantly shorter than in the others groups. The total number of gaze points (TNGP) on the left half of the screen increased significantly with age. The left TNGP in 4-6-year-olds was significantly smaller than in the other groups. The response search score (RSS) measured in 8 areas of the screen increased significantly with age. It was concluded that exploratory eye movements are useful markers to estimate the development of human visual cognitive function in childhood.No to hattatsu. Brain and development 09/2010; 42(5):340-5.
Article: Characteristics of exploratory eye movements in elderly people: possibility of early diagnosis of dementia.[Show abstract] [Hide abstract]
ABSTRACT: Visual cognitive dysfunction is one of the most important signs indicating the early stage of dementia. Thus, visual testing could be used as an aid to the clinical diagnosis of dementia. In the present study, exploratory eye movement was measured to evaluate visual cognitive function in elderly subjects, including those with dementia. We analyzed responsive search scores (RSS) from exploratory eye movements of 300 subjects who were examined with an eye mark recorder while viewing S shaped figures. Subjects were divided into three groups (dementia, intermediate, healthy) from the values of the Revised Hasegawa Dementia Scale (HDS-R), the Mini-Mental State Examination (MMSE) and the Clinical Dementia Rating. We further divided the intermediate groups into two subgroups, the high score and low score groups, based on RSS. In 202 subjects, Z-scores of voxel-based specific regional analysis system for Alzheimer's disease (VSRAD) were obtained from magnetic resonance imaging (MRI). RSS of the dementia group were significantly lower than those in the intermediate and healthy groups, in order: dementia < intermediate < healthy groups. RSS of the low score intermediate group was significantly lower than that of the high score intermediate group. There was no significant difference between the low score intermediate and dementia groups, or between the high score intermediate and healthy groups. No significant differences of either HSD-R or MMSE were observed between the low score and the high score intermediate groups. The Z-score of VSRAD using MRI in the low score intermediate group was significantly higher than that in the high score intermediate group. These findings suggest that RSS using an eye mark recorder is a useful psychophysiological marker to evaluate the early stage of dementia as well as at-risk elderly people.Psychogeriatrics 09/2010; 10(3):124-30. DOI:10.1111/j.1479-8301.2010.00327.x · 1.22 Impact Factor
Article: Neurophysiological analyses in different color environments of cognitive function in patients with traumatic brain injury.[Show abstract] [Hide abstract]
ABSTRACT: Colors are thought to elicit various emotional effects. Red, with its high likelihood of attracting attention, is considered to have an exciting, active effect; whereas green, with its low attention value, is considered to have a relaxing, sedative effect. Colors are also thought to affect human cognition and emotion. However, there have been few studies of the influence of colors in one's surroundings (e.g., the color environment and its effect on cognitive function). In this study, we investigated the influence of differences in color environments (red, green, or darkness) on cognitive function by analyzing the P300 component of event-related potentials (ERPs) elicited by oddball visual paradigms as a measure of cognitive characteristics in patients who had sustained traumatic brain injury (TBI). In 18 patients with TBI and 18 age-matched control subjects, ERPs were recorded in response to photographs of crying babies. We found that P300 amplitudes in the red environment were significantly larger in controls than in TBI patients, while those in both the green environment and darkness showed no difference between controls and patients. P300 latencies in the red environment and in darkness were significantly longer in patients than in controls. P300 latency in the red environment was significantly shorter than that in darkness. However, P300 latency in the green environment showed no difference between controls and patients. In healthy individuals, the emotional effects of the red environment enhanced cognitive function. In patients with TBI, however, cognitive function was reduced in the red environment. Furthermore, P300 amplitude and latency were strongly correlated with the time on the Trail Making Test (TMT), and the value of the intelligence quotient of the Wechsler Adult Intelligence Scale-III (WAIS-III). These findings suggest that P300 amplitude and latency are useful indexes for the evaluation of TBI patients, and that color environments affect cognitive function.Journal of neurotrauma 09/2010; 27(9):1577-84. DOI:10.1089/neu.2009.1119 · 3.97 Impact Factor
- Psychiatry and Clinical Neurosciences 05/2009; 63(2):253-4. DOI:10.1111/j.1440-1819.2008.01915.x · 1.62 Impact Factor
Article: Exploratory eye movement dysfunction as a discriminator for schizophrenia : a large sample study using a newly developed digital computerized system.[Show abstract] [Hide abstract]
ABSTRACT: In our previous studies, we identified that exploratory eye movement (EEM) dysfunction appears to be specific to schizophrenia. The availability of a biological marker specific to schizophrenia would be useful for clinical diagnosis of schizophrenia. Consequently, we performed the discriminant analysis between schizophrenics and non-schizophrenics on a large sample using the EEM test data and examined an application of the EEM for clinical diagnosis of schizophrenia. EEM performances were recorded in 251 schizophrenics and 389 non-schizophrenics (111 patients with mood disorders, 28 patients with neurotic disorders and 250 normal controls). The patients were recruited from eight university hospitals and three affiliated hospitals. For this study with a large sample, we developed a new digital computerized version of the EEM test, which automatically handled large amounts of data. We measured four parameters: number of eye fixations (NEF), total eye scanning length (TESL), mean eye scanning length (MESL) and responsive search score (RSS). These parameters of schizophrenics differed significantly from those of the other three groups. The stepwise regression analysis selected the TESL and the RSS as the valid parameters for discriminating between schizophrenics and non-schizophrenics. In the discriminant analysis using the RSS and TESL as prediction parameters, 184 of the 251 clinically diagnosed schizophrenics were discriminated as having schizophrenia (sensitivity 73.3%); and 308 of the 389 clinically diagnosed non-schizophrenic subjects were discriminated as non-schizophrenics (specificity 79.2%). Based on our findings we believe that the EEM measures may be useful for the clinical diagnosis of schizophrenia.European Archives of Psychiatry and Clinical Neuroscience 02/2009; 259(3):186-94. DOI:10.1007/s00406-008-0850-7 · 3.36 Impact Factor
Article: Developmental characteristics of visual cognitive function during childhood according to exploratory eye movements[Show abstract] [Hide abstract]
ABSTRACT: To evaluate the development of visual cognitive function in childhood, we examined exploratory eye movements in 84 healthy subjects viewing picture-based stimuli. Age-defined groups included 4- to 6-year-olds, 7-year-olds, 10-year-olds, 14-year-olds, 16-year-olds, and adults. In each group, 7 subjects were male and 7 were female. Exploratory eye movements, recorded as gaze points using an eye-mark recorder, were analyzed in terms of the total number of gaze points (TNGP); total eye-scanning length of gaze points (TESL); total number of gaze points on the left (l TNGP) and right (r TNGP) of the screen; and responsive search score (RSS) on the left (l RSS) and right (r RSS) of the screen. Both the TESL and TNGP increased significantly with age. The TESL and TNGP of 16-year-olds and adults viewing a repeat-comparison figure were significantly greater than when viewing a comparison figure. During the repeat-comparisons, the TNGP in 4- to 6-year-olds was greater on the right than the left; the opposite was true in 16-year-olds and adults. The RSS in 4- to 10-year-olds was greater on the right than the left; 16-year-olds and adults showed the reverse findings. Thus, in the repeat-comparison task, TNGP, TESL, TNGP, and RSS differences between left and right visual fields are useful biologic markers for estimating the development of visual cognitive function.Brain & development 02/2009; 31(10):750-7. DOI:10.1016/j.braindev.2008.12.002 · 1.54 Impact Factor
Article: Characteristics of a cognitive function during the concentration (card game) task by using fMRINeuroscience Research 01/2009; 65. DOI:10.1016/j.neures.2009.09.632 · 2.15 Impact Factor
Top Journals
Kurume University
Куруме, Fukuoka, Japan
- • Department of Neuropsychiatry
- • Cognitive and Molecular Research Institute of Brain Diseases
Fukuoka Prefectural UniversityTakawa, Fukuoka, Japan


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In a 2008 interview with Mike Kelley, writer Glenn O'Brien described the experimental art and music collective Destroy All Monsters—which Kelley founded in 1973 with fellow University of Michigan students Niagara (Lynn Rovner) and Jim Shaw and filmmaker Cary Loren—as "a mythic band. . . . It almost seemed like a great publicity stunt because . . . they never came to your town and there were no records." Indeed, the Ann Arbor "anti-rock band" performed only a handful of times, staging impromptu gigs at parties they were usually thrown out of. Their first release was a sixty-minute cassette tape of "distorto, psychedelic, chaotic, insanity, high energy level music," advertised for two dollars in their similarly riotous zine.
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I think it is time to feed. In Fact, I know that it is time. As the sun falls and the coldness of the night rises, my throat aches with thirst and my stomach rumbles with hunger. I am Morbius. Micheal Morbius. And I am cursed to forever feed on the lifes blood of others. The Smells hit me instantly. I can smell the trash in the alleys, the baking of fresh dough at the nearest Pizza Parlor, and the blood. The blood. Damn what a scent. It is sex and money. Cake and Ice Cream. It is the only thing that makes me feel alive. Makes me feel, ''human", for it is the only thing I actually desire.
I stand on a building. Watching. Waiting for what shall sustain me until the hunger rises within me again. And, as always. I find what I require. She is stunning. Raven of hair, tanned of skin. And full of breast and bottom. Italian if I ever saw one. I can smell the beauty. But Most importantly, I can sense what she truly has to offer one such as I. She walks into an alley, and my mouth begins to water. Yes. The hunger grows. And then, like always, the girl finds herself afraid and in danger.
Not from me of course. I swore off ''innocent blood" years ago. But like most New Yorkers, I know the danger this city holds, and as I'd hoped, the danger made it's presence known. I see them. Three men. Early to mid-thirties. Perfect prey. ''Yo babe, you lost?" A short man ask. I can not see his face. But, he is no more then 5'5. However his voice is deep. And full of New York bravado. ''I think i'm lost." The young woman responds. And I think to myself...Yes. Yes you are. Another lostsoul.However death would not find her on this night. Nor would shame or rape. Because Morbius hungers. And that is the driving force of my existence. ''Well check it out. Me and my n!ggaz, dont mind helping you out. For a price." The short man continues. She say's that she dose not have money. And they respond as expected. Money was never the objective here. I interfere of course. And the taste of blood sends a electromatic shockwave of euphoria through my veins. Reaching my soul. Bearhugging my heart. The hunger has been quenched. For now.


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Explore DC's Shaw neighborhood with this walking tour. You'll soon be returning to this hidden gem.
Ben's Chili Bowl Opening Virginia Location
Ben's Chili Bowl, the famous U Street restaurant, is opening its first location across the Potomac River in Virginia.
Bill Cosby Attends Ben's Chili Bowl 55th Anniversary Celebration
Bill Cosby was on hand Thursday to celebrate the 55th anniversary of a Washington institution — Ben's Chili Bowl.


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Flickr photoBox module
Easily add Flickr photos to your Joomla 3 website
- Category: Media Apps
- Release Date: Friday, 31 October 2014
- Filename: mod_hwd_flickr_photobox_3.zip
- Filesize: 34.57 kb
- Checksum: 850bd5de524d613b37154b656534f274aff005fc
Joomla 3 Compatibility
The module works great with all versions of Joomla 2.5 and the new Joomla 3.0.
Multiple Layouts.
Pick from multiple module templates, which are designed for vertical, horizontal, square and grid based layouts.
Easily Customisable.
Customise the photos you want to show from Flickr based on featured, users, albums or keywords.


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Supplement Facts
Serving Size: 25 mg
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But if Hillary Clinton does not run, Biden jumps up to the top, 45, 15, Deval Patrick in at 6. Governor Richardson, you're one of the few people I've talked to who believes that you could actually see a faceoff between Hillary Clinton and Joe Biden. That they both might run.
RICHARDSON: Yeah I think Joe Biden would not defer. I think he would run. Hillary Clinton would be formidable, no question about it. But I've known Biden over the years. He is somebody who's always wanted to be present. He's got the eye of the tiger. I mean he's going to all of these events. You've seen in his speeches, I was with him Friday morning, I think there could be a faceoff, but obviously Secretary Clinton is a formidable candidate who not only is appealing to the Democratic base, but is appealing to a Republican base who acknowledges the great work she did as Secretary of State.
STEPHANOPOULOS: Republican base supporting Hillary Clinton?
DEMINT: I don't think so George. You said it right, I mean she represents a third term of continuing in the same direction. I think Republicans don't need to focus on who's running right now, but what are the ideas that can inspire the American people.
We ran the last campaign on what was wrong with Obama. But it's time for Republicans, particularly conservatives that I represent, to show an inspiring winsome message to the American people. That's my priority at the Heritage Foundation, is not only talk about the right ideas, but to figure out how to connect with the American people.
ROBERTS: I think that third term notion is really strong. And I think it's a tough one for the Democrats. First of all we don't generally give people third terms.
STEPHANOPOULOS: Do you think it would deter Secretary Clinton --
ROBERTS: I don't think it will deter Vice President Biden. I think Secretary Clinton probably has a variety of things she's thinking about before she makes the decision to run. But my husband has convinced me that the historical imperative will make her run.
That she just, that this notion of being the first woman president, and of course everybody is coming to her and saying that. That you need to be the first woman president. You're the one who can do it. And that becomes very, very hard to resist.
STEPHANOPOULOS: That makes sense to me Mary. Do you agree?
MATALIN: No the third term issue is real. Ironically Hillary is to 2016 as George H.W. Bush was to 1992 when we got our clocks cleaned by the Clintons. And I think the reason she's been so successful as a woman will talk her out of it. She knows she can make an impact without it.
ROBERTS: She can make a huge impact.
MATALIN: Women think different and the historical paradigm goes to the way men think. My husband disagrees with that.
CARVILLE: Yeah I think it's more like 1988, when he went for the third term. But look, I have never, (inaudible) I've not seen one Democrat in the country that does not want her to run. And literally now they know that I would be for her and they come up to me and say, God please, please, tell her to run. Look at Nancy Pelosi, look at everything.
It has never been a front runner, a non-incumbent front runner like her since probably Eisenhower. And both parties wanted Eisenhower to run. And then once he said he was running as a Republican, it was all over. I've never seen, I can't tell you, if she ran, who would (inaudible) she is the most prohibitive front runner I have ever seen (inaudible).


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I was writing some native code on Android using NDK(jni).
I want to turn off the gcc compiler optimization.
For now I add
LOCAL_CFLAGS += -O0 to Android.mk, I'm not sure if it is working.
I wrote some code to test the loop overhead like this:
// gettime
for(int i = 0 ; i<10000;i++)
// gettime
The time difference is too small that I'm sure that the loop has been deleted by the compiler.
I can change
i to a volatile variable, but I want to test if I have turned off the compiler optimization correctly.
How can I know the optimization level that is used by gcc(ndk-build), can I set
make to verbose to get all the messages?
Thanks in advance.


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A collection of news and information related to Andy Rooney published by this site and its partners.
Top Andy Rooney Articles
Displaying items 1-11
Chuck Lorre to End His Vanity Card Missives?Story | Oct 7, 2014 | 8:30 AMIs No. 463 the end of the line for Chuck Lorre's famously specific vanity card messages? Since the days of "Dharma & Greg" in the late 1990s, Lorre has penned a new message to run as part of his vanity card slate at the end of every original episode of...
David Letterman: How long can the TV talk host stay on the job?
Yes, we're shallowStory | Jun 27, 2014 | 7:26 AMYears ago, Andy Rooney did his 60 Minutes curmudgeon shtick with the Sunday paper. He took up a Sunday edition of The Cincinnati Enquirer and methodically discarded the sections in which he was not interested, such as the classifieds ("I already have a...
Pop Culture 101: Final Exam 2011
Andy Rooney dies at 92; curmudgeonly commentator on '60 Minutes'
Celebrity deaths of 2011Story | Dec 20, 2011 | 1:35 AM1. Steve Jobs On Oct. 5, the 56-year-old Apple co-founder and CEO died of a rare form of cancer on his pancreas. Following his passing, President Obama said "There may be no greater tribute to Steve's success than the fact that much of the world...
Gone, but not forgotten, in 2011Story | Dec 23, 2011 | 10:57 AMYear-ending memories include those of people who made marks in entertainment before passing. In 2011, they included a significant number of behind-the-scenes talents whose television efforts endure. Andy Rooney: It's a sad irony that the pundit's death...
Small Wonders: Down a runway toward destructionStory | Sep 16, 2011 | 2:29 PMEver since M*A*S*H went off the air, I've been a little disillusioned with TV. That's not to say I don't watch, or like, certain TV shows: "30 Rock" and "Modern Family" stand out. While channel surfing, I will...
Long-time CBS broadcaster Andy Rooney dead at 92
The Crosby Chronicles: Burbank Unified's bulging parent packet
The Morning Fix: Rooney retires. 'Terra Nova' no go. Get your own glasses.Story | Sep 28, 2011The Morning Fix is a roundup of the day's media headlines....


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1974 Dodge W200
1974 W-200 Dodge Crew Cab Powerwagon found at the Talledega, AL Municipal Airport with 34k miles on original motor. Full body paint restoration captured in MOPAR magazine.
... $16,500
1974 Dodge Dart
Automatic transmission. New gas tank & sending unit, new timing chain & gears, new water pump, new radiator & hoses; original rally wheels & center pieces.
1974 Buick Electra
All original RUNS GREAT looks great drives GREAT must see CALL now
... $5000 obo
1974 Cadillac Eldorado
We have a nice caddy up for sale..because were newly business owners..no time..stays in storage for Mn ..weather from Sept - May..only able to drive summer months here (5
... $6000.00 or b.o.
1974 Chevrolet Caprice
I am selling this car for a family member. I drove this car for about 2 hours before writing this review. The car starts and runs perfect. The transmission shifts smoothly
... $7,000
1974 Porsche 911
Targa top, excellent condition, garaged, wide tires, runs great, smokes a little like a typical classic Porsche. Original color was white, could use a back-to-original paint
... $15,000
1974 Volkswagen Beetle
1974 Beetle with Baja finder kit.Stock engine 1600cc dual port, runs good. Trans good. Bob cat style header. No heaters. It's been in storage for 10 years and needs TLC.
... $1,200
1974 Mercury Montego
Take a look at this time capsule right out of the seventies. Only 28,000 miles and from the original family. Always garaged it's entire life. Comes with a 351 Windsor, auto
... $6,850
1974 AMC Gremlin
'74 AMC Gremlin. 232 straight 6 runs and drives. Original paint. 3 speed manual. 110,000 miles. New clutch, fuel pump, and other parts. Originally sold in Denver in 1974.
... $2,900
1974 Datsun 260Z
Beautiful 1974 260z in amazing shape. She has been in the family since the day she was driven off the lot. Body is 100% straight. Interior is excellent. It runs great;
... $6,499
1974 Chevrolet Nova
1974 Nova Custom Hatchback. PS, PB, aircon (not installed), 2.73 rear end. Original 350 motor, 350 trans, & Qjet carb. Motor bored .030 in Nov 1992 Lots of extra
... $3800.00
Stock #230CHIVehicle is located in Tinley Park, IL. 35 miles south/east of downtown Chicago, Off I-57 (708) 444-4488 - (708) 444-43161974 MG MGB for Sale ENGINE: 1798CC
... $15,995
1974 Chevrolet Nova
This is a true original SS Nova Custom Hatchback. My uncle bought this car new and I purchased it from him about 20 years ago. Needs minor restoration inside and out, yellow
... $7500
1974 Chevrolet Nova
1974 Chevrolet Nova..Race Car 2DR HT..Trophy Winner..World of Wheels Show Car..350 Small Block bored to 408..500hp w/High Performance Cam Shaft..Edelbrock Aluminum
... $
1974 Pontiac Grandville
1974 Pontiac Grandville Convertible, car has the original 455 Big Block engine, runs good, car runs and drives...Has nice frame and good floor pans, has a couple of rust
... $3400
1974 Austin Mini
Stock #373LOUVehicle is located in Memphis, IN. 16 miles north of downtown Louisville, off I65.(812) 294-1555 - (812) 294-10551974 Austin Mini for SaleENGINE: 998 CCBODY
... $10,995
1974 Jensen - Healey Roadster
1974 Jensen Healey Hardtop/convertible. 4 speed trans. Approx. 60k miles. Needs completion (brakes, suspension, upholstery - parts included in sale).
... $6,000
1974 Volkswagen Super Beetle
runs good but problem with the clutch. engine is good, always starts. the front hood is squished, all other body panels are in good shape. transmission was recently rebuilt,
... $2,000
1974 Chevrolet Corvette
Stock #288LOUVehicle is located in Memphis, IN. 16 miles north of downtown Louisville, off I65.(812) 294-1555 - (812) 294-10551974 Chevrolet Corvette Convertible for
... $24,995


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Marmalade Upside Down Cake
18 Jul 2010
|1⁄4 Cup (4 tbs)
|Brown sugar
|1⁄2 Cup (8 tbs)
|Walnut halves
|1⁄4 Cup (4 tbs)
|Pitted dates
|1⁄4 Cup (4 tbs), halved
|Chopped walnuts
|1⁄4 Cup (4 tbs)
|Sliced pitted dates
|1⁄2 Cup (8 tbs)
|Orange juice
|1⁄2 Cup (8 tbs)
|Yellow cake mix
|16 Ounce (1 Package Loaf-Size)
|Grated orange peel
|2 Teaspoon
Melt butter in a 9xl 1/2-inch round pan.
Blend in sugar, spreading mixture evenly over bottom.
Arrange walnut and date halves in center; sprinkle chopped nuts and sliced dates around edge.
Pour juice over all.
Prepare cake mix according to package directions; stir in orange peel.
Spoon over date-nut mixture.
Bake at 350° for 40 minutes or till done.
Cool slightly; invert on serving plate.
Rate It
0 Comments
Marmalade Upside Down Cake Recipe


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Learn more about Migi Nail Art Neon Polish Set - 8 Colors/4 Pens -Home Manicure Bright Bold:
Manufacturer: Migi Art
Mfg Part#: 105 MIGI NAIL ART - NEON
Sku: 234173037
See more in Nail Polish Sets
|Unique pen/brush allows you to brush on base color, then create amazing designs with the revolutionary pen tip. Set of 8 flashy neon colors: magenta/kelly green, hot pink/royal blue, deep purple/lemon, fiery red/orange. Includes step-by-step instruction book and cleaning pin. Limited edition.
Customer Reviews of Migi Nail Art Neon Polish Set - 8 Colors/4 Pens -Home Manicure Bright Bold
Amazing product!10/10/2012
This Migi nail art set (white neon kit) was exactly what I wanted! They make very fine lines and are great for making tiny designs. The colors are bright and vibrant and the best part is that you can register your product and receive free refills on two colors at a time for life! (shipping not included) Great product for the nail art enthusiast! I would definitely by another in the future!


text: > View Product Details Please select the size of the product. Please enter valid quantity. Alexander McQueen black texture oversize squared sunglasses overview details Retail: $560.00 Reduced: $380.99 10% Off : $342.89 color : We're sorry. This style is sold out. Black / Grey Alexander McQueen has an eye for edge - and proves it with a uniquely cool sunglasses collection. Color: Black / Grey Textured matte acrylic squared frames Graduated brown tinted lens Gunmetal logo plates at temples Grey wood grain patterned acrylic stems Offers full UV protection Case included Front piece measures 5¾'' wide x 2¼'' tall Vendor style #4189/S All measurements are approximate Acrylic; Italy; style#319753501


text:
Classified listings provided by Infoserve
Marks & Spencer
voice(01865) 248075
13 Queen Street, Oxford, OX1 1EJ
51.751696 -1.258725
Yahoo! User Reviews
Write a review Send to a Friend
Dear M&S Oxford's Queen Street branch, Whatever has happened to your cafeteria? I visit often and took 2 friends there on Saturday 8th December. The service, as it has been on the last 4 occasions when I visited, was dreadful! It was 11.30
Read the full review
Thank You!
May I make a suggestion. I love your brucheta (is it) cheese/tomato on bread toasted. But every time I get to your Oxford branch you are sold out, either mid week or week-end. This is usually about two o'clock. Could you save some to put out at
Read the full review


text:
You are using an outdated browser. Please upgrade your browser to improve your ReverbNation experience.
Aug 4
Live Music from Rock Power Trio: Snakebite
Jul 14
Live Blues/Rock from 'The Buzzz'
Jul 1
Charity Fundraising Event - Raising Money for Christies Cancer Research. Live Music from 9 bands including Northwest's Blues Rock Trio 'The Buzzz'
Jun 30
Live Music from NW Power Trio SNAKEBITE
Jun 30
Charity Fundraising Event - Raising Money for Christies Cancer Research. Live Music from 9 bands including Northwest Rock Trio: 'Snakebite' .
Sounds Like: Doyle Bramhall II, David Gray, Jeff Healey, Thin Lizzy
Label: Slindybug Music
Bio: Guitarist/Vocalist - Merseyside based Musician. Former guitarist for Progressive Rock Band 'FULA' www.fula.co.uk & has more recently worked with US based 'Captain Beyond'. Currently writing & recording original material & just released debut album "Dearest Dollymuck" (http://itunes.apple.com/alb...See Full Bio
: I liked a @YouTube video from @texasbluessrv http://t.co/KSToGMJxLm Stevie Ray Vaughan - Best Guitar Player - Sound Check - What?!


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- Filed Under
Ron Ross, who has spent 31 years teaching and coaching youth bowling, was honored by the Green Bay-Bay Area USBC Bowling Association with the Ray Mihm Award.
Ross, who spent the last 22 years working in the Green Bay Youth Bowling Association, received his award at the GBBA 44th annual Hall of Fame banquet Friday at the 1951 Restaurant in Green Bay.
The banquet was highlighted by the induction of Frank Buchachek, Jim Delvoye Sr., Jeff Ernst and Todd Mielke into the hall, bringing the membership to 188 since the hall's inception in 1969. Thirty-one previously enshrined members were on hand to welcome the new inductees.
In addition to Ross receiving the Mihm Award for the betterment and promotion of the sport, the association also handed out its annual accomplishment awards and three youths were presented with scholarships.
Ross started teaching youth bowlers in 1979 in Cheboygan, Mich., and continued when he relocated to Green Bay in 1990. He first worked at Western Lanes, and when that closed moved to the Ashwaubenon Bowling Alley.
In addition, he coached two years in the club program at Green Bay Notre Dame High School before organizing the club high school program at Pulaski High five years ago. He continues to coach that program and heads the middle school program that started two years ago.
"I used to take my children bowling (in Cheboygan) and nobody was available to coach them, so I did," he said. "My daughters (Kellie, who died of cancer at age 17, and Karen) got me into it and I just kept doing it."
Ross is also a good bowler - he has three perfect games - and has a grandson who is threatening to overtake him.
"My daughter Karen's son (William Durfey) has two 299 games," he said.
Ross, who said the award came as a surprise, has no intentions of giving up coaching and working with youth in the near future.
"I'm a Level Two (USBC certified coach) and I hope to climb the ladder to the next level if I can get the schooling in," he said. "This (working with youngsters) is not work to me. It's a joy to be with these kids."
Other awards:
■ Jim Moureau was honored for throwing the best series in the association during the 2011-12 season, an 846 in the St. Pat's League at Village Lanes on Feb. 5.
■ Alex Young, who relocated to Cincinnati at the end of last season, returned to accept the high average award for a 250 in the Procter and Gamble Matinee at Riviera Lanes. He also had the second highest, a 239 in the Green Bay Major at Willow Creek Lanes.
■ Scott Weber was honored for winning the GBBA Masters tournament by beating Matt Orvis in the final match. It was his fourth title.
■ Jake Johnson won the handicap singles title and scratch title in the association's annual tournament. He won the handicap title with a 796, including 27 pins of handicap, and the scratch title with a 769. Tim Czarneski and Mike Adams won the Baker doubles handicap and scratch titles, rolling a 925 scratch and totaling 1,041 with 116 pins of handicap.
■ The Willow Creek Burning Sensations team of Jeremy Jackson, John LePow, Brad Anderson, Dennis Farmer and Scott Karlin won the association's team event, beating the Ashwaubenon Fluid Systems team of Mike Nelson, Ken Piontek, Chad Watermolen, Dave Laundrie and Len Boerboom 1,270-1,210 in the championship match.
■ Aaron Krueger and Megan Devroy, both from Bay Port High, won the 38th annual Al Salmon $1,000 scholarships. The award, named in honor of the former secretary of the GBBA, is co-sponsored by the Green Bay West Side Lions Club and Green Bay Youth Bowling Association. Krueger and Devroy were named to the Press-Gazette junior first team last season after averaging 216 and 194, respectivel,y in the Green Bay Major Youth Traveling League.
Krueger now attends the University of Wisconsin-Platteville and Devroy attends Viterbo University in La Crosse. Both are on their college bowling teams.
■Abigail Kirchman of Green Bay Preble High won the $1,000 Maurice and Rose Lawyer scholarship, named in honor of a couple who spent years instructing youth bowlers. Kirchman now attends UW-La Crosse.


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Somewhere else is always home to someone.
Beyond responsiveness.
Beyond responsiveness.
International is being at home with your publics
"Domestic and foreign." How many companies still view the world divided this way? In fact, every country is "domestic" to its citizens, and citizens expect equal treatment from any company they are dealing with, for whatever purpose. Effective PR today requires a different vision of the world.
Most companies today understand they must be responsive to public expectations. However, not all understand that, beyond being responsive, they are also expected to behave in a responsible manner. Often, companies are surprised they have become suspect in public opinion, and are soon accused of misbehaviour, whether concerning environmental protection, health and safety, or other areas of public sensitivity.
- Most incidents are the result of misunderstandings, often related to cultural differences. This situation can be avoided - or even used to advantage- with the appropriate guidance from skilled professionals who understand how public opinion is formed. PROI Worldwide is composed of a group of consultancies which are "at home" with your publics worldwide, and which understand their cultures as well as they understand yours.
"Our PROI Partnership gives us access to a great network of independent partner agencies both in the U.S. and globally. Ready access to knowledge of key issues, the policymakers who influence them and the media who cover the action in cities across the globe provides added value to our clients."
Scott Widmeyer
Chairman and CEO
Widmeyer Communications


text:
We no longer carry Susan Ciminelli, however you might like Astara or AHAVA.
The Susan Ciminelli Glow. It's radiant and clear, and everyone can have it. Many of the world's most beautiful women entrust their skin care to Susan Ciminelli and her healing art of beauty. It's all about daily cleansing and protecting your skin with nature's finest ingredients and a healthy dose of intelligent advice.
Enjoy Susan's simple, refreshing daily regimen, and watch your skin improve before your eyes. That's all you need for a lifetime of beautiful skin.
To search Susan Ciminelli products by category, select from the drop-down menu below.


text:
mende1 Feb 10, 2013 3:32 AM
Re: working on iweb from a new mac in response to dooda game
Welcome to the Apple Support Communities
If I have understood, you have a new MacBook and you want to use iWeb with that MacBook. Is this correct?
If that's what you want, you can use Migration Assistant to migrate your files from the iMac to the MacBook, including your applications > http://support.apple.com/kb/HT4889 This will migrate your web info, also, so it's the better option
Old Toad Feb 10, 2013 10:05 AM
Re: working on iweb from a new mac in response to dooda game
Copy the iWeb application from you iMac to the Applications folder of your MB. Copy the Domain.site file from your Users/Home/Library/Application Support/iWeb folder of your iMac to the same folder on your MB. However, since you're running Lion on the MB be aware of the following:
In Lion and Mountain Lion the Home/Library folder is now invisible. To make it permanently visible enter the following in the Terminal application window: chflags nohidden ~/Library and hit the Enter button - 10.7: Un-hide the User Library folder.
To open your domain file in Lion or Mountain Lion or to switch between multiple domain files Cyclosaurus has provided us with the following script that you can make into an Applescript application with Script Editor. Open Script Editor, copy and paste the script below into Script Editor's window and save as an application.
do shell script "/usr/bin/defaults write com.apple.iWeb iWebDefaultsDocumentPath -boolean no"
delay 1
tell application "iWeb" to activate
You can download an already compiled version with this link: iWeb Switch Domain.
Just launch the application, find and select the domain file in your Home/Library/Application Support/iWeb folder that you want to open and it will open with iWeb. It modifies the iWeb preference file each time it's launched so one can switch between domain files.
WARNING: iWeb Switch Domain will overwrite an existing Domain.sites2 file if you select to create a new domain in the same folder. So rename your domain files once they've been created to something other than the default name.


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Summer is busy. Kids are out of school, people go on vacation, people eat lunch outside instead of in front of their computers. That means you might have missed something here on PurseBlog, but on this, the last day of June, we have you covered.
If you've been saving your sale season budget for the biggest markdowns, now's the time to pounce. MATCHESFASHION.COM's sale section is now up to 70% off, and there's still a pretty big selection of good stuff left at those prices, including bags from brands like Chloé, Givenchy, Saint Laurent and Valentino. As always, we recommend swift and decisive action; these are final markdowns, so the numbers aren't going to get any better.
Shop Up to 70% Off at MATCHESFASHION.COM
If you've been contemplating the purchase of a Céline bag for fall, we have some information you're going to want to consider while you plot. We just got ahold of the brand's Winter 2015 lookbook (which, confusingly, is the group of bags debuting with what the industry generally refers to as "fall" collections), and we've got all the images below, plus pricing for each bag.
If you thought sale season was over, think again. We dipped into the sale section at Saks yesterday, and it didn't take very long for us to start filling our shopping carts with totally lust-worthy bags, shoes and accessories, all up to 60% off. If you're looking for a serious deal on a super-fashionable piece at far below regular retail, you'd be smart to give Saks a look ASAP–many of the best items in the sale are 50% off or more, and that means they'll soon be snapped up.
Below, we picked over a dozen of our favorite Saks sale finds to get you started on a little bit of mid-week shopping. Check out our favorites from the bag, shoe and accessories sections below, or shop the full sale via Saks! Read More…
Bag: Valentino My Rockstud Embroidered Flap Bag
Price: $4,395 via Bergdorf Goodman
Why It's the Bag of the Week: Valentino usually reserves its intricate signature embroidery for runway dresses, so it's always a pleasure when some of it makes a jump to bags, as it does on this beautifully detailed top handle.
If Demi Lovato's Saint Laurent Bianca Sandals look familiar, that's because we've spotted her wearing them once before on TalkShoes! Even celebs have love affairs with their shoes. Malone Souliers was one of the designers we told you to keep on your radar this year, and the brand's Fall 2015 collection is making a very big impression in footwear. We also spotted Kiernan Shipka at the Coach 2015 Summer Party (our editor bumped into her there and confirmed how adorable she looked), wearing one of the brand's edgy wedges.
I know two things for sure about Oscar-winning actress Charlize Theron: she loves neutral handbags and hates the paparazzi. Both of those are defensible positions, in my mind, and they're both clearly on display when you thumb through Charlize's public handbag history, as documented by the dreaded paps.
It's always Fashion Week somewhere. Resort shows are barely done, but last week, the menswear world was traversing Europe, debuting Spring 2016 styles left and right. Most men's shows don't put much of an emphasis on accessories, but there is one very notable exception: Louis Vuitton.


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- Trends
- Golden Statements
- The Balsa Collection
- Beachy Blues
- Lightweight Nylon
- Mixed Materials
- Featured Texture
- Vault
- Categories
- Handbags
- Accessories
- Bracelets
- Tech
- Travel
- Gifts
- Graduation
Meet Anna, an updated version of our popular annabelle satchel. Slightly larger in size, with on trend detailing including new zip front pocket with cute tassel zipper. A classic handbag with an updated twist. Featured in brahmin classic croco embossed leather.
We offer free ground shipping and free returns on all orders placed through Brahmin.com. We ship to over thirty countries worldwide with more being added soon.Learn More


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DUSP is proud to announce that four of our IDG faculty have been honored with grants from the MISTI Global Seed Funds and other university partners for the following research proposals:
Dust storms can extensively disrupt socioeconomic activities and pose hazards to human health and the ecosystem; yet no one has made a systematic analysis of dust storms from an economic perspective. Using a case study for Beijing in 2000, we present a preliminary analysis of socioeconomic impacts of yellow-dust storms, integrating regional economic analysis models with environmental-economic evaluation techniques. Our analyses demonstrate that the
Yellow-dust storms (YDSs) have attracted increasing attention worldwide in the past decade. They can extensively disrupt socioeconomic activities and pose hazards to ecosystems, as well as to human health. In recent years, China has invested multi-billions of dollars to mitigate the impact of YDSs. However, the effectiveness of such YDS control programmes has rarely been evaluated. This research develops a causal model to quantify the environmental benefits of YDS control programmes in China, and further employs regional economic models to evaluate the ensuing economic impacts.
Design After Decline: How America Rebuilds Shrinking Citiesby Brent D. RyanUniversity of Pennsylvania Press, 288 pages
Climate change, food security, and energy efficiency have become universal challenges for global economic development and environmental conservation that demand in-depth multidisciplinary research. Biofuels have emerged as a decisive factor in the fight against global warming and air pollution from fossil fuel use, and they can play an important role in the development of poor as well as rich regions. In this work, we investigate the implications of biofuels for regional development in Brazil given its historic experience as an ethanol producer.
Energy is an important input in growing, processing, packaging, distributing, storing, preparing, serving, and disposing of food. Analysis using the two most recent U.S. benchmark input-output accounts and a national energy data system shows that in the United States, use of energy along the food chain for food purchases by or for U.S. households increased between 1997 and 2002 at more than six times the rate of increase in total domestic energy use. This increase in food-related energy flows is over 80 percent of energy flow increases nationwide over the period.
Greater use of renewable energy is being aggressively promoted to combat climate change by the Chinese government and by other governments. Agricultural straw is the kind of renewable energy source that would become a pollution source if it is not well utilized. We select the Shiliquan straw-based electricity generation project in Shandong Province, China as a case and assess environmental externalities of straw utilization in power plants by using life-cycle analysis.


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Jun 18, 2011 - by Steve Gerweck
Real name: Brandi Alexis Runnels
Height: 5'5″
Weight: 115 lbs.
Date of birth: June 23, 1983
Hometown: Ann Arbor, Michigan
Pro debut: April 2011
Trained by: FCW
– Brandi graduated from the University of Michigan. She worked as a TV news reporter in Michigan for two years. She then began modeling, working for Maxim, Hawaiian Tropic and other magazines and pageants.
– In March 2011, Brandi signed a developmental contract with WWE and was later assigned to Florida Championship Wrestling (FCW).
– On July 12, 2011, she made her WWE debut under the name Eden Stiles on WWE NXT as a ring announcer.
– In December 2011, at her request, Brandi was released from her WWE contract.
– On September 12, 2012, Brandi married WWE superstar Cody Rhodes.
– A short time later, she announced her return to the WWE developmental roster.


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Our Top Stories
Read all posts tagged Health Care
Kelly Wrote the President About Health Reform -- Today, She's With Him in Nashville.Posted byon July 1, 2015 at 3:09 PM EDT
Today, the President will be speaking in Nashville, Tennessee to talk about the ways health care reform is continuing to help millions of Americans. On his way over, he picked up Kelly Bryant to thank her for the letter she wrote him about the Affordable Care Act and to hear directly from her about how it changed her life.
The Letter the President Carried:Posted byon July 1, 2015 at 1:19 PM EDT
See the original letter that Natoma wrote and the President carried with him during the fight for health care reform.
Weekly Address: The Affordable Care Act Is Here to StayPosted byon June 27, 2015 at 6:00 AM EDT
In this week's address, the President called the Supreme Court's decision on the Affordable Care Act a victory for hardworking Americans, whose lives are more secure because of the passage of the ACA.
West Wing Week: 06/26/15 or, "This Is Healthcare In America"Posted byon June 26, 2015 at 3:31 PM EDT
Welcome to the West Wing Week, your guide to everything that's happening at 1600 Pennsylvania Avenue.
Today's Decision:Posted byon June 25, 2015 at 4:23 PM EDT
Hear from the President on the significance of the King v. Burwell decision, which preserved a key part of the Affordable Care Act.
Live Updates: The Supreme Court Upholds a Key Part of the Affordable Care ActPosted byon June 25, 2015 at 11:59 AM EDT
The President delivers a statement after the Supreme Court ruled to uphold the Affordable Care Act.
Celebrating LGBT Pride MonthPosted byon June 22, 2015 at 6:03 PM EDT
The LGBT community has contributed so much to the rich tapestry of our history, and over the past few years, we have taken historic steps to protect the health and well-being of our family, friends and fellow Americans who are lesbian, gay, bisexual or transgender.
The Faces of Health Care: Cody F.Posted byon June 22, 2015 at 12:31 PM EDT
What has health reform meant to this country? That's a question being answered by millions of Americans every day. Cody is one of them -- and this is his story.
Invest In Your "Healthy Self" (and Post a #HealthySelfie While You're At It)Posted byon June 11, 2015 at 9:47 AM EDT
Today, the Obama Administration is launching the "Healthy Self" campaign, to encourage healthy lifestyles, and connect people to the coverage and care they need.
Men: Take Charge of Your Health this JunePosted byon June 10, 2015 at 8:49 PM EDT
June is Men's Health Month, including Father's Day, and it's a great time to kick-start a new year with your best possible health.


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The temperature may have been a balmy 93 degrees when Cliff Lee threw his first pitch on Tuesday evening, but nobody likely felt the heat more than Brewers' right-hander Zack Greinke. Ever since the organization announced that they would skip his start and allow him to… [More]
Posts Tagged 'Zack Greinke '
Quick Hits: Trade Rumors
By J.P. Breen on July 24, 2012
Here are some brief trade rumors that have been swirling this morning: >> Doug Melvin had resisted tipping his hand in earlier weeks, but this morning's story in The Capital Times has some telling quotations. "And I don't view it as selling, we're just trying… [More]
Brewers scratch Zack Greinke for next two series
By Jaymes Langrehr on July 16, 2012
July is already a month full of wild, baseless speculation. When something like this gets tweeted during most people's lunch hours, things can get a little crazy: Now starting Wednesday vs. StL for the #Brewers will be Tyler Thornburg. Ron will address later. Greinke had… [More]
Mike Fiers, Fastballer
By Nicholas Zettel on July 12, 2012
Mike Fiers is one of the best surprises of the Brewers' 2012 season. As J.P. Breen stated yesterday, Fiers has yet to look back since the Brewers inserted him into their injury-depleted rotation. Even though Fiers has yet to reach his 50th inning pitched in… [More]
Brewers Not Planning On Selling … Yet
By J.P. Breen on July 7, 2012
With just over three weeks until the July 31 Trade Deadline, the Milwaukee Brewers need not rush into a decision regarding their position as a potential seller. More specifically, CBS Sports' Danny Knobler tweeted on Friday evening that the Brewers will not make any decision… [More]
Latest on Greinke Trade Rumors: Rangers, Braves
By J.P. Breen on July 4, 2012
Despite the Brewers' winning four-consecutive games, the trade rumors surrounding Zack Greinke have only intensified. ESPN writes that the Brewers have sent a special assignment scout to Texas' Double-A affiliate. That is where coveted prospect Mike Olt is currently assigned and serves as further proof that the… [More]
Fielding versus Bullpen: Efficiency
By Nicholas Zettel on July 3, 2012
My dad called the other afternoon to talk about the Brewers. He asked me a simple question: is there any one stat that I can use to explain the difference between the 2011 and 2012 Brewers. I hmm'd and haw'd for a bit, before saying,… [More]
Monday Musings: Greinke, All-Star Snubs, International Markets
By J.P. Breen on July 2, 2012
Another morning of haphazard thoughts following a series victory against the Arizona Diamondbacks at Miller Park. *** The Brewers' most recent wins against the Diamondbacks have delayed the Brewers from opening their doors for the trading season, but the remainder of Major League Baseball seems… [More]
Ryan Braun makes 5th All-Star team, Zack Greinke snubbed
By Jaymes Langrehr on July 1, 2012
For the fifth consecutive season, Ryan Braun will be playing in the All-Star Game. For the first time, though, it will not be as a starter. In his first four appearances, Braun was the leading vote-getter among National League outfielders, and was the leading vote-getter… [More]
Trade Winds Begin To Swirl Around Greinke
By J.P. Breen on June 28, 2012
Milwaukee avoided a series sweep in Cincinnati on Wednesday afternoon, taking advantage of a pair of home runs from Rickie Weeks and Cody Ransom en route to an 8-4 victory. With a record of 34-41, the Brewers climbed back to within 7.5 games of the first-place… [More]


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Governor Patrick defends judicial nomination
BOSTON - Governor Deval Patrick defended his nomination of Public Safety Secretary Mary Elizabeth Heffernan to become a district court judge. (Video by Glen Johnson, Globe Staff, 01/04/13)
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text: Submitted by blarime on Sun, 2014-02-23 19:55 Groups audience Ferdinand Hayden - 008 Vote Up Down +131 + Wednesday, March 5th, 2014 - 7:00pm to 9:00pm PST Presented by: The Ferdinand Hayden Chapter of Trout Unlimited at the Pour House in Carbondale, Colorado Refvreshements at 6 PM Film Starts at 7 PM Free and Open to the Public Who's attending this event? There is no one currently attending this event. Log in or register to post comments


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Cheap Home Decor: Crafting with Paper
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Cute as a Button Nightlight Shade
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Make a beaded lampshade for a nightlight, without any sewing. The secret's in the double-sided tape. By day it will look elegant and decorative, and by night it will light the way in a darkened room. This design makes a great gift, home decor, or finished product to sell at a craft fair.
- Self-Adhesive Lampshade Nightlight (Hollywood Lights)
- SEI Simple Set Buttons- Savory
- Paper: Scrappin' Creations Power Pad- Aqua dots, Stripes, Green Dots; Fibermark Cobblestone, Aster, Chai Latte; Blue, Green cardstock
- Green Braided Trim
- Kreinik 094 Star Blue #12 Braid
- Kreinik 008 Green 1/8" Ribbon
- Kreinik 009 Emerald 1/8" Ribbon
- Treasure Tape Shapes- Circles
- Treasure Tape Dots
- Diamond Beadlets
- Shallow pan or tray
Cut your paper into strips of varying width. Make each strip 1" shorter than your shade. Peel off your shade's liner and use it as a guide- trim your strips so they fully cover the design area without overlapping too much, and leave 1/2" above and below the strips for your trim.
Begin applying the strips centered on your shade. When you have finished, press with your fingers to smooth out any air bubbles.
Using your 1/8" ribbon, create a border around the top and bottom of your strips. Next, cover the rest of the exposed shade with your braided trim.
Place your Treasure Tape dots and circle shapes around your design. Peel back the red liners one at a time and position your buttons on them. Using your Star Blue braid, embellish around your buttons.
Finish your design by placing it in a shallow tray or ziploc® bag. Pour Diamond Beadlets over the remaining tape. Tap gently to remove excess beads. Place your shade on your nightlight, and enjoy!
Kreinik threads available through needlework stores or www.kreinik.com.
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kristinejacobs 454 8328
Jan 17, 2014
Ridiculous, every time I see the title of something I want to make there are only instructions and no photograph, so can't make anything.
- WAS THIS HELPFUL? YesNo
kristinejacobs 454 8328
Jan 17, 2014
Tis is ridiculous, each time I click on something I want to sew/make, there are instructions but no picture.
- WAS THIS HELPFUL? YesNo
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Gear Review
Steven Good
The Magic All-in-One Tool
Not, the lightest tool in the bunch, but it is the one with all the tools! This Wave tool is great for any job around the house or great option to keep in the car. I would not recommend for backpacking, as it is a bit heavier, but this is the go-to tool for home repair and a great one to keep on the belt if you need one for work with ample options. The best tools on this are the saw, pliers, and the nice long knife blade to make it quite the verstatile, compact too.
View More Details on Leatherman Wave Multi-Tool


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1. In a small bowl combine sugar, yeast and half a cup of water, mix and leave it to rest.
2. In another bowl combine water and salt, mix until dissolved.
3. In a large bowl pour the flour and make a well in the center, add the yeast, salt water, olive oil and water little at a time.
4. Mix until all ingredients are combined and smooth dough is formed.
5. Transfer the dough on a worktop and continue to knead until the dough becomes smooth and elastic.
6. Once done transfer the kneaded dough back into the bowl, cover it with a tea towel and let it rest in a warm and dry place for 2 hours or until it is double in volume.
7. Make delicious pizza from the dough and serve.


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Big Blue Frog
Big Blue Frog is the largest Family Entertainment Centre in Calderdale, covering over 8,500 square feet housing a play frame over 6 metres high with huge slides, ball cannon area and sports area!
For younger children from ages 0 to 5 they have also a separate toddlers play frame with slides, interactive play shapes ball pool and soft play area.
There is also a restaurant on site.
If you've had fun on your family day out to Big Blue Frog, tell us about it your visit, so other people will know it's a great place to go as well.
It may be worth checking out Big Blue Frog's website to see if there are any special events or seasonal fun things to do that may be going on during the day.
Stead Street
West Yorkshire
Telephone: 01422 363878
Click below for some other things to do with kids near to Big Blue Frog
Under 12 months enter FREE
Under 4s £3.25
Over 4s £4.50
Adults also enter for FREE Opening Times: 2013 Opening Details:
9.30am until 5.30pm daily.
Click DAYoutWITHtheKIDS logo at the top of this page, to take you back to the homepage for thousands of
family days out all over the country, or click this link to find West Yorkshire kids days out.
Finally. if you fancy a day out in the capital, click this link to find great things to do in london
Also you can find all your local things to do in Halifax for kids
Indoor Play Areas in West Yorkshire | Indoor Play Areas near Halifax
Nearest Counties
Family holidays in South Yorkshire | Places to go in North Yorkshire | Things to do in Lancashire
Places to visit in East Yorkshire | Things to do in Leeds | Family things to do in Cumbria


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CEO Heading Samsung's TV Business May be Asked to Oversee Its Mobile Business
A news report says that, Samsung Electronics may consider an overhaul of its management which could lead to the company's TVs and home appliances head of to oversee the company's mobile business, which is not doing so well. The reshuffling in its management could begin as soon as December.
Amazon Fire TV Stick will offer stiff competition to Neflix and Hulu Plus
Amazon's Fire TV Stick is a new streaming device - just like the Google Chromecast or the Roku Streaming Stick - which plugs into an HDMI port, and is powered by microUSB. Though the Fire TV Stick is essentially a smaller version of Amazon's Fire TV full-fledged streaming device, it is well worth its $40 sticker price.
Lowe's to Introduce Robots in Store for Customer Service
Soon you may not find the hardware man to help you in stores anymore! On Tuesday, one of the largest U. S hardware retailer and DIY stores, Lowe's, said that it is going to introduce its first robot clerk in-stores.
Amazon Should Take Careful Steps after the Fire Phone Flop
On Thursday, Amazon the Seattle based company reported a third-quarter loss along with a disappointing forecast figure for the holiday season sale. From the starting of the year the company has lost twenty eight percent of its value.
Google's Slowing Clicks on Ads Worry Investors and Analysts
On Thursday, Google reported its third-quarter earnings and the figures have raised several questions in the minds of the analysts. The earnings report showed that the Internet giant is revealing signs of a slowdown in its extremely profitable business of search advertising.
Hewlett-Packard to Split Its Business in Two
Reportedly, Hewlett-Packard Co, the robust Silicon Valley company which is trying to adapt to the changing times with the spurt of mobile and online computing, now plans to divide itself into two separate companies. This action will allow it to put in more focus on the fast-growing corporate services market.
Yahoo Urged to Buy Rival AOL Inc.
Marissa Mayer the CEO of the struggling internet company Yahoo seems to be receiving some un-called for advice about measures that could turn around the performance of the company.
Siemens Plans to Acquire Dresser-Rand for $6 billion Says Sources
Sources having knowledge of the matter said on Sunday that Siemens AG the German engineering conglomerate is going in for a multibillion-dollar deal for buying Dresser-Rand Group Inc. the oil-equipment manufacturer of U. S. The deal could be announced as early as Monday said the persons.
iPhone 6 Mobile Payments will be Accepted by Walgreens & CVS
Walgreens-6 Mobile-Payments.jpg
Tuesday is much awaited by all those inquisitive about Apple's iPhone 6, the iWatch as the company is supposed to unveil its features on that day.
The company is preparing for the "special event" in Cupertino, California which s its hometown. It has also invited the media for the September 9 unveiling of its new model and fresh features.


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Results 1 to 7 of 7
November 22nd, 2010 #1Registered User
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Academy of Art University Investigation
We are investigating whether Academy of Art University lied to prospective students about its programs and the benefits of a degree. We also are investigating whether it paid incentive compensation to its sales people (admissions representatives). If you are a student or former student, or a former employee, we would very much appreciate hearing your story and point of view.
Dominic Valerian
Gallo + Associates
Hide this ad by registering as a memberDecember 7th, 2010 #2
Are there any investigations going on with the I.A.D.T. artschools?
December 8th, 2010 #3
If you're going to sue anyone, sue the Art Institutes. That's a flagrant rip-off, and it's ruining people's financial lives as well.
Last edited by SlowDaddie; December 8th, 2010 at 06:52 PM.
December 8th, 2010 #4Registered User
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- Sep 2007
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- Thanked 271 Times in 199 Posts
Last edited by Meloncov; December 8th, 2010 at 11:57 PM.
December 8th, 2010 #5
Even though this is pertaining to AAU (to which I've never attended). I will have to agree with SlowDaddle about the Art Institutes. As a student who attended and quit one of the branches, I must say the amount of debt one can incur for a sub-par education is staggering. Not to say that all are bad necessarily, however, there are questionable ethics.
My two cents.
Last edited by Monkabit; December 9th, 2010 at 12:54 AM.
December 17th, 2010 #6Registered User
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To follow-up on my earlier post, we now suspect that prior to June 2007, AAU was not in compliance with California's ban on paying incentive compensation to admissions representatives. If so, students who enrolled before June 2007 may be entitled to a refund of a substantial portion of their tuition. If you enrolled in AAU prior to June 2007 or have information about AAU's admission representative compensation during this period, we would like to hear from you at email@example.com.
Thank you,
Dominic Valerian
Gallo + Associates
December 17th, 2010 #7The Chaotic Dreamer
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- I Hate, New Jersey
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@SlowDaddie: Craig McKracken and Genndy Tarkosky went to CalArts. In fact, Tarkosky and McKracken became friends because they MET there. XD


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#3 of 39
greeting cards, still life greeting cards, eggs art print greeting cards, lemon art print greeting cards, grapes art print greeting cards, carrots art prints greeting cards, bread art prints greeting cards, garlic art prints greeting cards, tomato art prints greeting cards, onion art print greeting cards, cheese art print greeting cards, wine jar greeting cards
Dalgis explores beauty and ugliness and the gains and losses of life, in her wonderfully complex oil painting cast on regular canvas and wood. She combines a unique poignant style with an abundance of details, intensely rich colors and complex compositions to bridge the expansiveness of emotive expressionism with the realities of the physical world.Drawing from her deep sense of spirituality,dreams and imaginative wanderings, Edelson creates worlds infused with symbolism and meaning meant to probe the intuitive flow of human experience. Inspired by Goya,Dali,Kahlo and the old masters, Edelson's images are dedicated to detailed renderings but also surrealistic, as she uses geometric forms to add layers of meaning to her figures.She takes...
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The awards will be held for the year 2009 on April 18, 2010. Recently, a formal function was held in Bangalore. An expert panel of judges will select the winner. Ambarish will be the brand ambassador for the event. Kaviraj has penned the theme song for the event while Ricky Kej has composed the music for it.
rockline venkatesh, karnataka film chamber of commerce, innovative film awards, zee kannada, ricky kej, kank


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Peas In Creamy Mushroom Sauce
|Frozen peas
|2 Cup (32 tbs)
|2 Tablespoon
|Sliced mushrooms
|1 Cup (16 tbs)
|All purpose flour
|1 Tablespoon
|Milk/Light cream
|1 Cup (16 tbs)
|1 Pinch
Conventional method: In saucepan, bring small amount of water to boil; add peas. Reduce heat to simmer and cook for 4 to 5 minutes or until tender; drain.
Meanwhile, in saucepan, melt butter over medium heat; cook mushrooms for 2 minutes. Sprinkle with flour; cook for 1 minute, stirring constantly. Whisk in milk, salt, pepper and nutmeg; cook for about 4 minutes or until smooth and thickened. Stir in peas.
Microwave method: In microwaveable dish, cover and microwave peas and 2 tbsp (25 ml) water at High for 5 minutes. Let stand for 2 minutes; drain.
In 4-cup (1 L) microwaveable measure, microwave butter at High for 1 minute. Add mushrooms; cover and cook for about 2 minutes or until tender, stirring once. Stir in flour; whisk in milk until smooth. Microwave at High for 2 to 3 minutes or until smooth and thickened, stirring once. Add salt, pepper and nutmeg; stir in peas.


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The "vault" can be accessed through the hidden area in the library.
The Dreadspire Vault lies behind the locked door within the Library. Need to complete the quest Frustrated Functionary in order to be able to open the locked door and proceed to the Mayong event area. The door is far too thick to slip through using illusion trickery.