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"There is no question that for some patients opioid use is appropriate, but there is also increasing evidence that long-term use can lead to addiction, fatal overdoses, sleep apnea, falls in the elderly, reduced hormone production, and now erectile dysfunction," says Dr. Deyo, who has spent more than 30 years studying treatments for back pain.
For this study, Dr. Deyo and colleagues identified 11,327 men in Oregon and Washington enrolled in the Kaiser Permanente health plan who visited their doctors for back pain during 2004. The researchers examined the men's pharmacy records for six months before and after the back-pain visit to find out if they had filled prescriptions for opioids and for ED medications or testosterone replacement.
Opioid use was categorized as "none" for men who did not receive a prescription for opioids; "acute" for men who took opioids for three months or less; "episodic" for men who took opioids for more than three months, but less than four months and with fewer than 10 refills; and "long-term" for men who took opioids (a) for at least four months or (b) for more than three months with 10 or more refills. Anything more than 120 mg of morphine equivalent was categorized as high-dose use.
More than 19 percent of the men who took high-dose opioids for at least four months also received ED medications or testosterone replacement. More than 12 percent of men who took low-dose opioids (under 120 mg) for at least four months also received ED medications or testosterone replacement. Fewer than 7 percent of men who didn't take opioids received ED medications or testosterone replacement.
Researchers found that age was the factor most significantly associated with receiving ED prescriptions. Men 60 to 69 were 14 times more likely to receive prescriptions for ED medication than men 18 to 29.
Depression, other health conditions (besides bac
|SOURCE Kaiser Permanente
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Guillaume Hoarau (R) and Kevin Gameiro of Paris St-Germain celebrate after scoring against Olympique Lyon during their French Ligue 1 soccer match at the Gerland stadium in Lyon February 25, 2012. (REUTERS/Robert Pratta)
PARIS: An injury-time winner from substitute Kevin Gameiro earned Paris Saint-Germain a narrow 2-1 victory at Dijon on Sunday that preserved their place at the top of the Ligue 1 table.
PSG had Mohamed Sissoko sent off prior to half-time and saw Siaka Tiene's opener cancelled out by Steven Paulle before Gameiro slotted home in the 91st minute after Jeremy Menez led a counter-attack from a Dijon corner.
Dijon upset PSG in the French League Cup in October and they had looked set to hurt them again, but Gameiro's goal means that Carlo Ancelotti's side will remain top even if second-placed Montpellier beat Caen in Sunday's late game.
PSG enjoyed the best of the first half, with Dijon goalkeeper Baptiste Reynet tested by both Javier Pastore and Menez, who also flashed a volley narrowly over the crossbar from Pastore's dinked pass.
Visiting goalkeeper Salvatore Sirigu had to parry a volley from Benjamin Corgnet, however, and the momentum swung in the hosts' favour in the 41st minute when Sissoko was harshly shown a straight red card for a robust challenge on Eric Bautheac.
Despite the setback, PSG went ahead after just four minutes of the second half, with Guillaume Hoarau eluding Chaher Zarour near the byline on the left before crossing for Tiene to tap home his first goal for the club.
Pastore dragged a shot across goal and wide as PSG looked to extend their lead but in the 76th minute Dijon drew level and PSG's fragility at set-pieces was once again exposed.
A right-wing corner from on-loan Chelsea midfielder Gael Kakuta was flicked on at the near post and Paulle arrived unmarked to nod the ball into the net.
With PSG looking shaky in defence, Dijon made the mistake of over-committing men forward for an injury-time corner kick and Gameiro was the beneficiary, drilling the ball home from Menez's pass to claim only his second league goal in 2012.
Compounding Dijon's frustration was the knowledge that a point would have been enough to take them out of the relegation zone, whereas Gameiro's goal meant that they remained in the bottom three.
In Sunday's other early game, fifth-placed Rennes squandered a chance to put pressure on the teams in the Champions League qualifying berths as they were held to a 1-1 draw at home to Auxerre, who climbed off the foot of the table.
On Saturday, Lyon reignited their challenge for a top-three finish by winning 2-1 at third-placed Lille and closing to within four points of a Champions League place.
Fourth-placed Saint-Etienne were also able to capitalise on Lille's slip-up, coming from behind to win 2-1 at Valenciennes and moving to within a point of the defending champions.
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Elite: Dangerous will be an Xbox One exclusive on launch, but will eventually come to PS4 too6 March 2015
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Elite: Dangerous on Oculus Rift preview: Hands-on with the best VR experience we've had13 June 2014
Having not played any of the Alpha phases of Elite: Dangerous, David Braben and his Frontier development studio's reimagination of his original BBC Micro space simulator, we jumped at the chance to check out the latest build of the PC game. And were even... >>
Elite: Dangerous Premium Beta opens, buy your way in for £10010 April 2014
Frontier Developments has launched the Premium Beta phase of Elite: Dangerous, the multiplayer rehash of one of the most famous and revered games of all time. The full Premium Beta, with mutiplayer functionality, isn't due to start until 30 May, but... >>
Zoo Tycoon Xbox One preview: If we could talk with the animals26 August 2013
Switching the development duties for the new Zoo Tycoon game to Frontier seems to be an inspired move. Not only has it plenty of experience with simulation games, having had enormous success with Rollercoaster Tycoon 3 and subsequent expansion packs in... >>


text: The No Longer Alone wiki last edited by catfightfan on 04/30/14 07:20PM View full history When a skirmish between the Hulk and Captain America leaves Rick Jones injured, Cap is left with a choice: bring Jones to safety or pursue the Jade Giant?Captain America tries to reign in and help the Hulk and in the procces gets a new sidekick.> Steve is alone on a quiet empty street when suddenly two massive green hands push thru a wall! The Hulk has just arrived !! The military is once again chasing the Hulk, and Steve changes into Captain America and attempts to help the bewildered Hulk as Rick Jones shows up. The Hulk harms Rick..without meaning to.. and takes off! Cap picks Rick up and takes him to his apartment to recuperate. Cap leaves him sleeping and goes out to his balcony to think. After a while he hears footsteps behind him and turns to face......Bucky? Cap angrily tells Rick to get the costume off and as Rick walks away to do just that, Cap has a change of heart. An alert sounds and now Cap and Bucky are together as a team again!!!!!! They go to a secret underground Hydra lair and fight the hoards of Hydra! Cap and Bucky are split up and a Hydra agent wearing a power vest attacks Cap. The fight is intense as Cap uses his shield to push them both thru a wall! We see Bucky cleverly eluding The hoards, and cut back to the agent in the power vest claiming Caps shield. Cap is defeated??? As Bucky comes charging back in to avenge Cap, the agent reveals himself to be none other than Cap himself!!! Madame Hydra escapes and as Cap and Bucky leave the scene Cap lets him know that he has proved himself to be worthy of wearing the costume of Bucky!!! This is a classic Jim Steranko drawn story!!


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* Indicates a PR sample, contains affiliate links.
1. Gressa Skin's Lip Boosts in Bare and Lavish *
These Lip Boosts are the perfect consistency and the Bare Lip Boost is one of the best my lips but better shades of pink even for my slightly pigmented pout. I also really love the subtle berry shade of Lavish for a nice wash of color that is not only really cute but very moisturizing too!
2. Kari Gran's Tinted Lip Whip *
This is the lip balm I've been keeping reaaaally close to me lately, because it does such a great job at conditioning my extremely dry lips. It goes on a very sheer wash of pink but is a very cute bubblegum pink color in the jar. This lip whip also has a really fresh scent of peppermint that is so refreshing too!
3. RMS Beauty's Defining Mascara
If you read my full review on both the Defining and Volumizing mascara from RMS Beauty then you probably know that the Defining mascara surprisingly thickened up my lashes a lot more than the Volumizing one. So I've definitely been reaching for this one a lot more because I just love how it makes my lashes look! It also separates and lengthens my lashes perfectly too, and you definitely need this in your life if you're still looking for a natural mascara! #whatareyouwaitingfor
4. ILIA Beauty's Tinted Lip Conditioner in Jump
Now this lip conditioner is absolutely gorgeous! It looks amazing on every skin tone imaginable (from what I have seen) and is perfect for the warmer weather we've been having too. It's such a nice balm-like texture like all of ILIA's lip conditioners which makes it super easy to touch up and go when you're out enjoying the beautiful weather. I also love that it can be built up pretty intensely too. Check out my full review of it here.
5. Revolution Organics Beauty Balm in Sunkissed
I have been loving orange blush lately so I have been overdosing on this particular beauty balm this month. It gives my cheeks the perfect sunkissed glow and orange makes me look very bronzey which I love. I've been indulging in the orange makeup trend with this beauty balm and it's been fab! Have you?
6. Kahina Giving Beauty's Night Cream *
I love love love Kahina's Night Cream and I now understand all the hype surrounding this night cream! I won't give away too much since I have a full review of it coming soon but it has the best texture which means I apply it both day and night and it is not at all too heavy. And did I mention that it is anti-aging?
7. RGB's Nail Polish in Too Red
I get tons of compliments on this red nail polish every time I wear it and unlike their polish in Pansy this has the perrrrfect consistency so it's so easy to apply. It also has amazing staying power and has the glossiest finish without a top coat which I don't have at the moment for this particular polish so I love this! This has been on my toes and fingernails the entire month of April and I am completely obsessed.
What have been your faves this month? Have you tried any of these products? If not, these are definitely must tries!
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