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BOULDER, Colo., Nov. 12 /PRNewswire/ -- Aktiv-Dry LLC has been awarded an SBIR research grant from the Center for Disease Control and Prevention (CDC) to explore the formulation of certain siRNA products as inhalable dry powders that might eventually be used to treat pulmonary disorders such as RSV. Brian Quinn, Ph.D., from Aktiv-Dry, is the principal investigator.
As an intervention strategy for viral infection, new approaches for treating RSV include delivering to the respiratory system short interfering ribonucleic acid oligonucleotides (siRNAs), the molecules that induce RNA interference. Quinn will use Aktiv-Dry's proprietary supercritical carbon dioxide process, CAN-BD, to formulate an oligonucleotide as a powder consisting of micro-scale particles capable of deposition in the lungs.
"The best way to treat an illness is to get the medicine to the principal site of infection, which in the case of RSV is in the lungs," said Quinn, president of Aktiv-Dry. "This proof-of-concept project will attempt to reformulate a siRNA product as a stable, dry powder consisting of particles 1 to 5 microns in diameter. When manufactured under pharmaceutical conditions, infants and children could inhale such particles into their respiratory tracts through the aid of an active dry powder inhaler."
Respiratory syncytial virus (RSV) infects essentially all children within the first two years of life and is the most common cause of bronchiolitis and pneumonia among infants and children under one year of age. It is also a significant cause of morbidity and mortality in the elderly. Each year, RSV infections lead to more than 100,000 hospitalizations and about 2,500 deaths. Current treatment for RSV generally consists of only treating its symptoms, which include fever, runny nose, cough, and sometimes wheezing. No effective drug for treating the RSV infection itself is widely available, nor is there an approved vaccine to prevent RSV.
"If our research is
|SOURCE Aktiv-Dry LLC
Copyright©2007 PR Newswire.
All rights reserved


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Posts Tagged: Belgium and the Belgian-Influenced
Illinois: Sofie 2012, Goose Island Beer, Chicago
Posted by Alan McLeod on Friday, February 22, 2013 in Illinois, Saison and Biere de Garde, Belgium and the Belgian-Influenced, Beer Stores and Beer Shopping - 20 comments
The beer that proves craft v. crafty is a big sloppy fib - and well within the range of possible futures for brewing generally. $8.99 last weekend just across the border. I look for it and its siblings whenever I cross over as it is one of the best values in good beer. • Lemon, pears and fine …
Quebec: Mons Abbey Dubbel, Belgh Brasse, Amos
Posted by Alan McLeod on Friday, November 9, 2012 in Quebec, Belgium and the Belgian-Influenced
Ah, Canada. Nothing like having to travel the 25 miles south from the Thousand Island Bridge border crossing to get your hands on a bottle of beer from the next province to my east. But the bit of the province to the east that is about 400 km due north of here. You see this all the time. Canada …
New York: Scythe & Sickle, Brewery Ommegang
Posted by Alan McLeod on Saturday, October 13, 2012 in New York, Belgium and the Belgian-Influenced, Ingredients, Techniques and Packaging - 2 comments
A harvest ale. An ale with not only four malts but four separate grain species: barley, wheat, oats and rye. And, unlike collaboration beers, you can actually pick out the characteristics each of these partners brings to the beer. There is the spice note of rye in the finish, the grassy tang of … read more »
Belgium: Saison De Pipaix, Brasserie à Vapeur
Posted by Alan McLeod on Friday, September 14, 2012 in Saison and Biere de Garde, Belgium and the Belgian-Influenced
A beer apparently from a shed. OK, if the BAer brewery page is to be believed a one and a half story brick shed in wee Pipaix-Leuze, Belgium. With a steam punk lauter tun. Neato. • The beer pours light caramel under fizz head that resolves to a white rim and foam. Not strong on the nose …
Beer Cocktails: Are Raspberries In Gueuze So Wrong?
Posted by Alan McLeod on Thursday, July 26, 2012 in Beer Cocktails, Belgium and the Belgian-Influenced, Sour Beer Studies, Beer and Food - 4 comments
Not a complex beer cocktail. Just fresh raspberries in Gueuze Cuvée René from Lindemans, the gueuze that our monopolistic overlords allow us at least in the summer. The nice thing about raspberry is that it has a lot in common with gueuze. Dry acidity. OK, that is about it but it's not like I am …
Has The Law Protected A Tradition Or Innovation?
Posted by Alan McLeod on Saturday, July 14, 2012 in California, Belgium and the Belgian-Influenced, Ingredients, Techniques and Packaging, Beer and Law - 4 comments
It is always odd when the law is used to protect something. There are policies at play, interests and stuff that can't quite have a finger put upon it. Which makes one think about this: • Gov. Jerry Brown on Friday signed a bill supported by Democrats and Republicans that ensures certain …
Belgium: Cuvee v.d. Keizer 2011(B), Carolus, Het Anker
Posted by Alan McLeod on Thursday, July 12, 2012 in Belgium and the Belgian-Influenced, Big Bombs - 2 comments
What a name. Fully set out this is Gouden Carolus Cuvee Van De Keizer Blauw 2011 from Brouwerij Het Anker in Mechelen. The Lake Chaubunagungamaug of beer names. • As it is 11% and good for ten years at least this is infanticide at 17 months or so. Yet it is pretty fine stuff. It pours light …
Belgium: Faro, Brouwerij Lindemans, Vlezenbeek
Posted by Alan McLeod on Wednesday, June 27, 2012 in Belgium and the Belgian-Influenced, Sour Beer Studies
I have never had a faro before. Had one in the stash for a while. Then found another. So had no reason to not have one. That is as deep as it gets. G Dot O Dot in TBT confirmed my suspicion that in the past people did not like sour beers more so much as were more comfortable sweetening them. I … read more »
Book Review: Geuze And Kriek, Jef Van den Steen
Posted by Alan McLeod on Monday, February 20, 2012 in Belgium and the Belgian-Influenced, Sour Beer Studies, Books and Book Reviews - 2 comments
Hmm... it's subtitled "The Secret of Lambic." I was a bit concerned before I got past the cover that this would be a book about one secret. Happily, as I worked my way through this book, I realized it was more part of a slightly troubled translation than the actual promise of what lay between the …
Belgium: Mort Subite Kriek / Framboise, Keersmaeker
Posted by Alan McLeod on Saturday, February 11, 2012 in Beer Cocktails, Low Strength Beer, Belgium and the Belgian-Influenced, Sour Beer Studies - 4 comments
Six and a half years ago, I posted a post about sweet lambics that was one of my early entries in my effort to start to understand the world of sour, brackish, funky, tart and otherwise weird beers. You may have noticed on thing from that sentence. Yes, I was drinking sweet to understand sour …

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text: Brett Favre: The Musical A.J. Daulerio and 37 othersEditDelete Invite manuallyPromoteXDismissXUndismissBlock for deadspinHide The New Yorker's faux musical savant, Ben Greenman, used the Gunslinger as his latest subject. Love this verse: And now, the present precipice/I just can't say what happens next/Will I suit up for the Vikings?/Did I send explicit texts?[NewYorker] » 8/05/10 3:45pm 8/05/10 3:45pm


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Average Customer Review
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37 of 38 people found the following review helpful
5.0 out of 5 stars Pure Genius
First of all, the New York influence and Patti Smith comparison has been much overstated by now; PJ Harvey has repeatedly said that Smith has never musically inspired her and that the vocal likeness is coincidental. That out of the way, I must now heartily endorse Stories From the City, Stories From the Sea – a truly great rock album and one of my personal...
Published on 14 Feb. 2004
3 of 5 people found the following review helpful
3.0 out of 5 stars Some Very Good Songs But A Mixed Bag Overall
Typical that PJ's most praised album is also her least interesting. Very clearly a "New York" album much of it sounds like Patti Smith retreads - without any of the spark that Patti brought to her best records (more like retreads of Patti's 80's AOR sadly - at times you start expecting PJ to sing People Have The Power), for that blame the ultra-slick production and...
Published on 15 Jan. 2011 by Amazon Customer
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37 of 38 people found the following review helpful
5.0 out of 5 stars Pure Genius,
By A Customer
This review is from: Stories from the City, Stories from the Sea (Audio CD)
First of all, the New York influence and Patti Smith comparison has been much overstated by now; PJ Harvey has repeatedly said that Smith has never musically inspired her and that the vocal likeness is coincidental. That out of the way, I must now heartily endorse Stories From the City, Stories From the Sea – a truly great rock album and one of my personal favourites of all time.
This LP marks a major musical progression for Ms. Harvey. Like her early albums, these songs are built around the three-piece band dynamic of guitar, drums and bass; but this time around she adds lush layers of melody and reverb by bringing subtle shades of keyboard, E-Bow, accordion and harpsichord into the mix. The resulting sound is rich, graceful, tuneful and quite unlike anything she's done before.
Big Exit kicks off the album in glorious, psychedelic, hard-rocking style. It opens with a wall of bellowing loudspeaker vocals, clattering Led Zeppelin drums and staccato electric guitars before melting into a swooning chorus of "Baby baby ain't it true/I'm immortal when I'm with you". The second song Good Fortune is a joyous, romantic, violent Bonnie and Clyde fantasy in which she dreams of going on the run and living a dangerous gypsy existence with her lover. It soon becomes clear that she is celebrating a new type of romantic love and positive energy on this record. Having covered darker territory throughout her career, she enjoys playing with Beatlesque guitar pop and delicate orchestration on songs like A Place Called Home, One Line, This Mess We're In and the ethereal closer We Float. These are soaring, poignant songs of hurt and hope. Beautiful Feeling and Horses in My Dreams are unplugged ballads of raw, stark beauty. In contrast, at least five songs (Big Exit, The Whores Hustle and the Hustlers Whore, Kamikaze, This Is Love and bonus track This Wicked Tongue) are as tough, fierce and hard-rocking as anything off Dry or Rid of Me.
Stories From the City, Stories From the Sea won the Mercury Music Prize, two Grammy nominations, two BRIT nominations, appeared on numerous album-of-the-year polls and prompted Q magazine to vote PJ Harvey the greatest female rock star of all time. For all the critical praise, it met an unusual reaction from some longtime fans. Grumpy doom-and-gloom miserabilists who favoured her darker early work seemed to cynically begrudge Harvey her new-found happiness on this record, and indie snobs felt put out that their "dirty little secret" was now being enjoyed by a wider audience. This has happened to every great rock act who has dared to edge from underground cult worship to mainstream success, from Pixies and Sonic Youth to White Stripes or Queens of the Stone Age. She certainly hasn't gone soft by any means. The fiery spirit, emotional intensity and musical passion are all still there; the heart beats stronger than ever before.
This magnificent album demands to be heard by as many people as possible.
29 of 30 people found the following review helpful
5.0 out of 5 stars A modern rock masterpiece,
This review is from: Stories from the City, Stories from the Sea (Audio CD)
I'm too lazy to bother reviewing many albums here but I had to make an exception for this one. Why? Because it's one of the greatest rock albums I've ever heard and I want new people to know just how good PJ Harvey really is.
Stories From the City, Stories From the Sea is a masterpiece from start to finish. PJ outdoes herself on raw, fiery, hard-rocking guitar cuts like Big Exit, This Is Love, Kamikaze, The Whores Hustle and the Hustlers Whore and the brilliant bonus track This Wicked Tongue. The spectacular opening song Big Exit speeds past on blazing, careening power chords and powerhouse drumming courtesy of master percussionist Rob Ellis. Good Fortune and One Line both have a dizzying romanticism and surging energy that make them similarly irresistible. And listen out for the quaking monster riff that opens This Is Love as PJ lustily declares, "I can't believe life's so complex when I just wanna sit here and watch you undress" - it manages to be an electrifying, deliciously sexy hard-rock song and witty, tongue-in-cheek fun at the same time. These songs see PJ Harvey revisiting the punky, bluesy power-trio days of her early albums Dry and Rid of Me, and they reveal her oft-cited influence of Led Zeppelin, Jimi Hendrix and other classic 70s rock. It's not all bluster and noise though. Gorgeous songs like A Place Called Home, You Said Something, We Float and the heartbreaking Thom Yorke duet This Mess We're In will surprise you with their sparkling melodies and a cleaner production than previous PJ Harvey records. There are also two minimalist, stripped-down acoustic numbers - Beautiful Feeling and Horses in My Dreams - that bring a nicely eerie atmospheric touch to proceedings, nestled in amongst the louder tracks.
The whole album is brilliantly sequenced so that it feels like a loosely conceptual song cycle about a person arriving in a big scary city (Big Exit), finding an exciting but dangerous love (the Bonnie and Clyde references of Good Fortune), then enduring romantic heartache (This Mess We're In) and angry turmoil (Kamikaze) before fading out on a promise to "Take life as it comes" (in We Float). But a few minutes after We Float has reached its dreamy, hopeful end, the head-banging bonus track This Wicked Tongue unexpectedly charges in to bring the record to its bitter, explosive, hardcore finish.
PJ Harvey is a unique, genius-level talent and Stories From the City, Stories From the Sea shows her off at her peak: her voice is brilliantly expressive, her lyrics are unusually poetic, and her guitar playing has a ringing dynamic clarity. She simply has a rare brand of emotional intensity and pure passion that cannot be faked.
I strongly urge all you readers to buy this album now - you will NOT be disappointed!
3 of 3 people found the following review helpful
5.0 out of 5 stars Back to her best,
Peter Lee (Manchester ,United Kingdom) - See all my reviews
This review is from: Stories From the City Stories From the Sea (Audio CD)
After the comparatively low-key "Is This Desire?" and "To Bring You My Love" Polly Harvey has returned to the sound of "Rid of Me" and "Dry" with devsatating effect. This is her strongest set of songs for years and she sounds more confident than ever.
The songs were written in New York and Dorset and are consistently strong. This time around there are no dabblings with tape effects such as the slowed-down "Katherine" which appeared on "Is This Desire?", instead the songs are straighter than ever, mainly up-tempo, always good.
Thom Yorke appears on three tracks (backing vocals on two, and lead vocals on the stunning "This Mess We're In") which is rather appropriate as this has just replaced Radiohead's "Kid A" as my current favourite album of the year. Excellent stuff from start to finish. If you're already a fan you'll love this; if you're not it might just convert you.
2 of 2 people found the following review helpful
5.0 out of 5 stars A definate must,
This review is from: Stories from the City, Stories from the Sea (Audio CD)
If you're new to PJ Harvey then this is the perfect albumn to start off with. Its the most accessable by far of all her albumns, which is not meant either as a praise nor as a negative.
This albumn is often described as more pop then her others, which is somewhat true but should not be a put off for any of the more heavy fans. And anyway it's Polly Jean Harvey, you cant exactly get further away from pop!
For any Thom Yorke fans 'This mess we're in' has Thom singing lead whilst Polly sings and voices over in perfect biting harmony. And thom is also featured both with back up vocals and piano peices in both 'One Line' and 'Beautiful Feeling.'
'This is Love' will probably be one of the ones you've heard before as one of Harvey's more famous works, but this is no means the only standout of the albumn. If im being truly honest i would say that not a single song on this album is redundant.
Polly jean shows she hasnt lost that raw, animalistic edge in such songs like 'this wicked tongue' 'big exit' 'kamikaze' 'this is love' these prove just how perfect polly and a guitar is together. and with peircing lyrics expressed with polly's insane range of chilling highs and just pure awesome lows.
For those who like it softer, but no less great, listen to 'One Line' 'We Float' 'Good furtune'
This is a perfect start point to journey into the depths of polly jean. I say to Rolling Stone who said "the best album of her career" hell no PJ Harvey has a load more to offer, so check out her other albumns; 'Is This Desire?' and 'White Chalk' Trust me you will not be dissapointed. As PJ Harvey says herself she wanted something of 'absolute beauty. I want this album to sing and fly and be full of reverb and lush layers of melody.' -She got it right.
2 of 2 people found the following review helpful
4.0 out of 5 stars Is this PJ at her 'lightest'?,
Brida "izumi" (United Kingdom) - See all my reviews
This review is from: Stories From the City Stories From the Sea (Audio CD)
Before listening to this album, I had heard her other album, TO BRING YOU MY LOVE. That album was intensely dark, really quite disturbing in places. STORIES FROM THE CITY, STORIES FROM THE SEA is quite a change to this dark side of Harvey. Although she is still able to pack a few punches, STORIES is defintiely more accessible than TO BRING YOU MY LOVE.
Love finally seems to be something that can be celebrated, as well as being the bringer of intense pain. In "One Line", Harvey describes such a hopeful love relationship, describing how a connection between two loving hearts may be able to keep the two people safe in todays warring world.
"This is Love" is an incredibly catchy song that also sings about the joys of love (with just a bit of lust thrown in for good measure). It reminds me of a honeymoon period for relationships, where you can't get enough of the other person, and all you want to do is have physical contact with them.
As another reviewer has suggetsed, if you are new to PJ's work, this may be the best place to start. It is a fantastic rock album, providing a different side to PJ. Even when she seems to be celebrating the good points of love and relationships, there is an undoubtable amount of emotion and rawness to make sure that PJ's ture essence of herself remains withing her music.
A great album - recommended.
10 of 11 people found the following review helpful
5.0 out of 5 stars Look Out Ahead I See PJ Come *Classic*,
Phill "thanewdanger" (London) - See all my reviews
This review is from: Stories from the City, Stories from the Sea (Audio CD)
The Mercury music prize winning album "Stories From The City,Stories From The Sea" is one of the best progressive rock albums since i can remember now i have to say my rock knowledge isn't the greatest but i know enough to know that this is a classic.PJ Harvey in the early 90's followed the footsteps of Marianne Faithfull & Patti Smith and brought the feminist image and told the world that women can do rock too!
It starts off with the rather up-beat jingley "Big Exit" probably about paranoia on some level it's one of my favourite PJ songs so far and she sings it with such raw passion.
"Good Fortune" which was one of the singles lifted from the album is one of the most commercial sounding songs of her career it's a good song although not as good as the rest "A Place Called Home" which is my favourite on the album it's such an enchanting song in a dark sorta way, her voice is very raspy on this one and thats one reason why i love it so, again a more commercial sound from her usual underground style.
"One Line" & Beautiful Feeling" are more mellower tracks the latter a nice chilled out love song which keeps at the same tempo all the way through as opposed to "One Line" where it picks up and gets quite hard but still keeping a still mellow vibe.
One of the highlights is the duet with Thom Yorke of Radiohead on "The Mess We're In" a utter masterpiece they both sound fantastic together i think PJ sounds really beautiful on this one.
"This Is Love" is a cool jumpy rock song reminds me of the Yeah Yeah Yeahs (PJ is probably one of Karen O's inspirations)
and enjoyable song the only song that dosnt grab me and i that i never really listen to is "Kamikaze" is has a rhythm and blues undertone which i was surprised at but even still a song i can't seem to like.
The 6 minute closer is a true highlight "We Float" could be well a truly be a masterpiece in it's own right a throughly enjoyed every minute of this one
Top 5
1.A Place Called Home
2.Big Exit
3.The Mess We're In
4.We Float
5.Beautiful Feeling
PJ is just like all of the great women of rock throughout the world shes an utter legend in her own right bringing back female rock that sorta disappeared for a while in the 80's (although some kept it alive Tina Turner,KD Lang...etc)and revived come 1992
"Stories From The City,Stories From The Sea" is in my top 25 rock albums where it damn well should be
10 of 11 people found the following review helpful
5.0 out of 5 stars A 21st Century masterpiece,
Jason Parkes (Worcester, UK) - See all my reviews
(No. 1 Hall OF FAME REVIEWER)
This review is from: Stories from the City, Stories from the Sea (Audio CD)
Despite lukewarm critical reviews, I warmed to this album. I have not stopped playing it since getting it last December. I had forgotten how great PJ Harvey is...
This is one of those albums that you just end up playing all the time. It is also a return to form, after the slightly patchy 'Is This Desire?'(which is hard work to listen to. Tho' any record that features 'The Sky Lit Up' can't be anywhere close to average).
The early sound of 'Dry' & 'Rid of Me' is recalled on tracks such as 'Big Exit', 'Kamikaze' & 'This Wicked Tongue'. Though sonically this is much better- with the return of Rob Ellis & Birthday Party/Bad Seed/ awesome musician, Mick Harvey.
'Horses in My Dreams' evokes Patti Smith, imagine a blend of 'Birdland' & early tracks like 'Hair'& the demo of 'Legs'. 'The Whores Hustle...' is closer to the sound of 'To Bring You My Love'; while 'You Said Something' sounds like that album's 'The Dancer' backed by REM (not far from the 3rd Liz Phair album).
'Good Fortune' is the catchy signature tune of the album: "talking about time travel & the meaning of it all". The follow-up singles, 'A Place Called Home' & 'This is Love' both possess moments where they just turn into something transcendent. Polly Harvey is one of those fantastic vocalists- her blues are worlds...
Thom Yorke pops up on a few tracks, he is in the background for the morose ballads 'One Line' & 'Beautiful Feeling' (the latter close to 'Is This Desire?' & 'Hardly Wait'). Yorke's duet with Polly is great- better than her duets with Bjork, Nick Cave & Tricky (tho' possibly not Mark Linkous). The key track- & best song of this century so far- is 'We Float'. This song takes Polly's water-obssession to previously uncharted Jungian depths (see 'Water', 'Ectasy','Down By The Water', 'Angelene'). It is notable 'Dry' collaborater Head returns to work on this track. It sounds like an excerpt from a soundtrack- with Polly encapsulating existence as she knows it over the top. She sounds great with just a guitar; she sounds greater with the massive background to 'We Float'. The lyrics are fantastic, definite & unsure- capturing the philosphy of the future in a manner close to Samuel Beckett: "I can't go on. Go on": "This is kind of about you/This is Kind of about me...But one day we'll float/Take Life as it Comes"...
This is true soul music. Great also to see the continued presence of photographer Maria Mochnacz. The only question now is where for PJ Harvey next? (she was rather splendid in Hal Hartley's 'The Book of Life'). Until then, we'll float..................................
3 of 3 people found the following review helpful
5.0 out of 5 stars beautiful,
By A Customer
This review is from: Stories from the City, Stories from the Sea (Audio CD)
I bought this album about two years after i had heard "Good Fortune". I put off buying the whole album because for some i reason i had it in my head that i wouldn't like it. Im usually a fan of more electronic music, and i thought this might be a bit to rocky for me...however i was very wrong.
It is rocky, but it is one of my most favourite CDS. There is a song for every mood in here from "This is love" which will make you want to jump around and scream your head off in true rock style, to "We Float" an absolutely beauticul track, very uplifting...
I reckon if you like music you should buy this, i doubt it will let you down.
I'm actually going to put it on right now...
26 of 29 people found the following review helpful
4.0 out of 5 stars More Hustle than Whore,
Mr. Stuart A. Douglas "SD" - See all my reviews
This review is from: Stories from the City, Stories from the Sea (Audio CD)
Following an unfortunate incident when an idiot ran me off the road a month or so back, the trusty Micra had to go into the garage and, consequently, I had to remove the hundred or so CDs which had accumulated there (this was less because I feared that sticky fingered mechanics would be unable to resist the temptation to pinch a pile of Nusrat Fateh Ali Khan cds and more in case they stood on the cases scattered in the passenger side foot well).
The result of this is that now I have my car back the only CDs as yet available are those in the little rack thing hooked round the driver's sun visor, which I had forgotten all about. And the only thing worth listening to in there (even though I put every CD there at some point) is PJ Harvey's album 'Stories from the City, Stories from the Sea', which I had always dismissed as being a bit too straight up and down rocky to be a good PJH LP.
However, given the choice of listening to 'not at her best' PJ Harvey or, to take a random example of the other CDs available, a Graham Nash live bootleg from 1993, well I've had PJH on the car CD player pretty much constantly for the past week or so.
And it's a truly great album - possibly her very best which really is saying something. From the exultant semi-shout "I'm immortal when I'm with you" in album opener 'Big Exit' to the haunting refrain on the second from last track, 'We Float' ("We float/Take life as it comes"), this is a confident album from an artist at the top of her game.
Where once she asked 'Is this Desire?', now she states 'This is Love'. Which is a pointer to the fact that this is a much happier album than we're used to from Polly Jean. Not that it's exactly the Crazy Frog tune or anything, but it's a long way from 'Plants and Rags' on her first album ("Plants and rags/Ease myself into a bodybag") to this album's 'Beautiful Feeling' ("A smile from San Diego/He's still a boy/Two ends to every rainbow/And a train from Mexico"). 'Good Fortune' continues the positive vibe and even the Thom Yorke duet, 'This Mess we're In", manages to be less than morose (although not a patch on Yorke's earlier duets with Drugstore or Bjork).
For old time fans, the spiky guitar and the confrontation is still there, though - any album with a track called 'The Whores Hustle and the Hustlers Whore' isn't likely to crack the core pre-teen market - but there's a happiness behind it which too often seemed missing in her earlier work. Even the tracks which ostensibly sound like they could be expected to be on the negative or sleazy side often turn out to carry you along on an upbeat guitar line or an unexpected Polly Jean wail (see especially the ending of 'the Whores Hustle' for a wonderful example of Ms Harvey's Yma Sumac-like vocals).
And then, just when you think that the old evil Polly is gone, along comes 'This Wicked Tongue Says', a barely produced burst of pure invective, as Polly curses everyone over almost, but not quite, out of control guitar. This is a track that could fit onto 'Dry' without a problem.
Stand out track for me in an album full of potentials, though, is 'Kamikaze', which is so good that I'm banned from playing it in the car when there's anyone else present, lest I take my hands off the wheel to play the drum rolls on the steering wheel and end up involved in a road traffic incident.
Which is where we came in...
2 of 2 people found the following review helpful
5.0 out of 5 stars We Float,
By A Customer
This review is from: Stories from the City, Stories from the Sea (Audio CD)
Far and away the best album I bought in 2000. This review is obviously fairly superfluous, so I'll keep it brief. The range of Polly's singing appears to have increased on this album, from her usual demanding deliberations to a more sensual expression, possibly due to increased confidence in its capabilities. Thom Yorke's voice is used to astonishingly haunting effect on a few tracks, more so than he manages with his own band, even. I was less than totally enamoured with "Good Fortune" when it was released as a single, and I was reluctant to buy the album as a consequence. However, the song makes total sense and is utterly enjoyable when listened to in sequence with the rest of the album. Is synergy at work here?
It was so good to have finally found an album with a degree of depth last year.
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Stories from the City, Stories from the Sea by PJ Harvey (Audio CD - 2003)
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by Caleb O. Brown, CATO Institute
A former slave, Frederick Douglass did not know his actual birthday. His mother, also a slave, called him "my little Valentine" on her occasional visits to her child. She travelled miles, usually at night, to spend just a few minutes with her son. Douglass chose February 14 to mark his birth.
Here is Cato adjunct Robert McDonald detailing the life of one of liberty's greatest champions.
Here's text based on MacDonald's speech and more from Libertarianism.org on Frederick Douglass's story and his impact on the rights of women and the libertarian tradition. Most importantly, here are three short essays by Douglass worthy of your consideration.
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Chateau Grand Corbin D'espagne St. Emilion 2004
Chateau Grand Corbin D'espagne - Bordeaux - France - Saint Emilion
Professional Wine Reviews for Chateau Grand Corbin D'espagne St. Emilion 2004
Rated 90 by Robert Parker
The Despagne family has accomplished terrific things at this estate since 1988, and the 2004 is another sleeper of the vintage. Opulently-styled with a dense purple color as well as sweet blueberry, blackberry, cedar, and spice characteristics, this medium-bodied, pure, ripe St.-Emilion is approachable, but promises to evolve for 10-15 years.
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Additional Information on Chateau Grand Corbin D'espagne St. Emilion 2004
Chateau Grand Corbin D'espagne
Varietal: Red Bordeaux
Bordeaux red wines are widely regarded as being the finest red wines produced anywhere in the world, regularly topping awards lists and generally being amongst the most sought after and collectable bottles available. The secret to their success and their particularly memorable and refined characteristics is the fact that Bordeaux red wines are made from a blend of grape varietals, most commonly from Cabernet Sauvignon and Merlot grapes, helped by a touch of Petit Verdot or Cabernet Franc. The other two key Bordeaux grape varietals which are also used in the blend of many of these excellent wines are Malbec and Carménere, although it is becoming less common to see these in use today. The art of blending primarily Cabernet Sauvignon and Merlot grape varietals is something which has been much imitated around the world, as it produces a wonderfully balanced, rounded yet massively complex and flavorful wine, ideal for oak aging The acid and tannin levels in each of these grape varietals is balanced and tempered by the blend, and generations of expertise has gone into the careful selection and cultivation of such quality grapes.
Region: Bordeaux
The Bordeaux region of France is possibly the most famous and widely respected wine region in the world. Known primarily for its exceptional blended red wines, made most commonly with Cabernet Sauvigon, Merlot and Petit Verdot grape varietals, it also produces superb dry white wines (both blended and single variety), alongside the highly esteemed sweet wines of Sauternes. All of these wine types use a careful mix of traditional wine-making methods alongside modern techniques, as well as more experimental and unorthodox practices such as turning their grapes over to the noble rot which intensifies the flavors in the sweet wines. Bordeaux benefits greatly from its position amongst wide river basins, and the cooling Atlantic breezes which blow across the rolling vineyards which cover this region.
Country: France
French winemakers are subjected to several laws and regulations regarding the wines they produce, and how they can be labeled and sold. Such procedures are designed to increase the overall quality of the country's produce, and also to ensure that wines made in each particular region or appellation are of a character and type which is representative of the area. Thankfully for consumers of wine world-wide, the French have a particularly high reputation to uphold, and seem to do so flawlessly. Every year, wineries from all over France produce millions upon millions of bottles of fine wine, making the most of their native grape varieties and the excellent terrain which covers most of the country. From the expensive and exquisite red wines of Bordeaux and Burgundy, to the white wines and cremants of central France, the French are dedicated to providing the world with wines of the highest quality and most distinctive character.
Appellation: Saint Emilion
Saint Emilion is a very special sub-region found in France's Bordeaux, and is situated on the highly esteemed and world renowned right bank of the Gironde river. Here, the mineral rich gravel and clay based soils provide plenty of nutrition and character to the grape varietals which are grown, and the warm and sunny climate helps them ripen each year to their fullest. The majority of the chateaus in Saint Emilion produce blended red wines, using a carefully balanced blend of Cabernet Sauvignon, Cabernet Franc and Merlot grapes. The result is something truly wonderful – finely crafted red wines which express all of the finest points of each varietal, and holding plenty of fascinating and complex character, flavors and aromas which have helped make this sub-region one of the best in the world.
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A favorite of the local arty set, and also of office workers dropping in for after-work drinks and dinner, this sharp-edged suit-grey eatery serves up modern French bistro food with a Japanese twist. Don't miss the Wagyu beef with beets, artichoke, and chicory. The bar, which stays open late, serves coffee from 10 am, and has a range of light meals including spiced crisp pig's ear with fresh apple and garlic chive.
1 Flinders La., Melbourne, Victoria, 3000, Australia
Website: www.vergerestaurant.com.au
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By James Curcio
As luck would have it, Google had just launched SnuggleNet, billing it as "an iPhone you could snuggle." And you were getting no kind of affection from virtual friendships. It seemed a worthwhile purchase.
SnuggleNet is a peripheral, already connected to all the social networks you've been a part of since you were a child. "It knows what you need and when you need it," the advertisements said.
After a difficult day of work, it will wrap you in a warm embrace and say, "hey, you need to watch some Venture Brothers. And fuck that, you know, thing that piece of shit @heretic357 was saying about you on Twitter—"
You will quickly discover SnuggleNet is kind of a notorious shit mouth.


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Basic Stir Fried Gravy
10 Jul 2009
This basic stir fry gravy is so simple yet lends loads of flavor to your stir fries! Made with a blend of asian ingredients like soy sauce, oyster sauce and rice wine along with sesame and soybean oil, the basic stir fry gravy is easy to prep and add to your recipes of choice.
|Chicken bouillon/Chicken broth
|3⁄4 Cup (12 tbs)
|1 Teaspoon
|Soy sauce
|1 Tablespoon
|Oyster sauce
|2 Tablespoon
|Chinese rice wine/Pale dry sherry
|1 Tablespoon
|Black pepper
|1⁄8 Teaspoon
|Sesame oil
|1 Teaspoon, blended with soybean oil
|1 Tablespoon, dissolved in 2 tablespoon cold water
|Cold water
|2 Tablespoon
Note: Flavour your wok oil by frying 4 slices peeled fresh ginger root about 1 inch in diameter and 1 /8 inch thick and 1 clove of chopped garlic in it before you start frying anything; this adds to the flavour of the gravy.
Combine all ingredients and stir well.
When your stir fry is cooked, pour the well mixed gravy over the fried ingredients still over a medium to high temperature and stir the gravy until it thickens and clears.
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Basic Stir Fried Gravy Recipe


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A locator or signaling device and a detector system for locating lost dentures includes a button or insert that can be mounted on the surface of an existing denture. An insert can also be implanted in a new denture. The internal signaling component is surrounded by a resin layer that can be used to bond the locator button to the existing denture and will also isolate the internal signaling component form the denture wearer's oral cavity. The internal signaling component is responsive to an electromagnetic field and emits a detectable signal when the denture is located with a specified interrogation zone or search area. Signaling components having magnetic characteristics that are altered by an incident variable electromagnetic field can be employed. The preferred location for the locator, locator strip, marker or button is on the interior lingual surface of the flange of a mandibular or lower denture. The denture can also include an RF passive transponder embedded therein which can be detected at short range by a portable detector. The RF passive transponder includes a logic component having a unique code that is transmitted when the denture is subjected to an electromagnetic field emitted by the portable detector.
1. A system for locating a lost denture comprising an RF passive transponder containing an integrated circuit device connected to a coil and a portable reader having a transceiver for emitting an electromagnetic field to generate a voltage in the coil so that a code stored on the integrated circuit device is then transmitted through the coil to the transceiver for initially detecting the presence of a lost denture containing an RF passive transponder in a localized area larger than the area in which the code stored in the integrated circuit device can be read wherein the denture also includes a magnetic member embedded in the denture and a stationary transmitter-detector for detecting the presence of the magnetic member in the lost denture, the range at which the magnetic member can be detected being greater that the range at which the RF passive transponder can be detected.
2. The system of
3. The system of
4. The system of
5. A denture that can be located and identified when lost, comprising:
a radio frequency transponder embedded within the denture, the transponder emitting a coded radio frequency signal when activated by an external electromagnetic field, the coded radio frequency signal comprising means for identifying a specific denture; and
an electromagnetically actuated device also embedded within the denture, the electromagnetically actuated device emitting an electromagnetic signal when activated by an external electromagnetic field, the electromagnetic signal emitted by the electromagnetically actuated device being stronger than the coded radio frequency signal emitted by the radio frequency transponder so that the presence of the denture can be detected at a greater distance than possible for identifying the coded radio frequency signal.
6. The denture of
7. The denture of
8. An assembly for locating a lost denture comprising:
at least one signaling device secured to the denture, the device emitting a signal when the denture is located within an external electromagnetic field;
a portable transmitter-receiver emitting a first electromagnetic field that activates a signaling device to emit a signal detectable by the portable transmitter-receiver when a signaling device is within a first distance from the portable transmitter-receiver; and
a stationary transmitter-receiver emitting a second electromagnetic field that activates a signaling device to emit a signal detectable by the stationary transmitter-receiver when a signaling device is within a second distance from the stationary transmitter-receiver, the second distance being greater than the first distance so that the portable transmitter-receiver comprises means for searching for a lost denture and the stationary transmitter-receiver comprises means for detecting the denture passing through a fixed location prior to realization that the denture has been lost or misplaced.
9. The assembly of
10. A method of mounting a passive transponder in a denture comprising the steps of evacuating a trench in an area of a denture base adjacent molars on the denture, the trench extending to a rear edge of the denture base so that one end of the trench is open, followed by the steps of placing the transponder in the trench and then filling the trench to secure the transponder in the denture base, wherein a syringe is used to place the transponder in the trench.
11. The method of
12. The method of
This application claims the benefit of prior co-pending Provisional Patent Application Serial No. 60/224,268 filed Aug. 10, 2000.
1. Field of the Invention
This invention is related to dentures and to an apparatus and method for locating lost dentures. This invention is also related to a signaling device that can be mounted in existing dentures or incorporated in new dentures and to a detector for locating the signaling device, attached to the lost denture within a certain area or an interrogation zone. The detector area or interrogation zone could be located at a building exit leading to a trash disposal collection area.
2. Description of the Prior Art
Medical institutions and long term care facilities in which patients and residents may suffer from diminished mental capacity or simple forgetfulness frequently have difficulty locating personal articles that have been misplaced or lost. One problem that is often encountered is that the patients or residents tend to lose or misplace their dentures. Patients or residents in such facilities often inadvertently throw their dentures in trash receptacles, leave them in pockets of clothing that is taken to a laundry facility or leave then on serving trays after meals. In rest homes and nursing care facilities, the resident may also place the dentures under sheets, in closets or in drawers where they can be difficult to locate. In some cases, the dentures are subsequently located by the institution's personnel, who cannot identify the owner. In other situations the lost dentures are inadvertently disposed of in the trash or simply cannot be found within a reasonable time.
Although this problem occurs even when the institutions personnel are vigilant, it is especially upsetting to the residents and to their relatives. Lost dentures can be costly to replace, and relatives can be especially upset that the institution cannot keep track of their older relative's dentures. In many cases, the institution must replace the dentures and is not reimbursed.
Medical institutions do encounter problems with lost articles in other contexts. For example, U.S. Pat. No. 5,923,001 discloses a surgical sponge detection system for use in an operating room in which detectable RF tags are attached to the sponges. U.S. Pat. No. 5,664,582 discloses a marker that can be used on a surgical instrument. However, these devices are used only within a controlled environment, and the problem of lost dentures arises because it is not possible to control the environment in which the loss may occur.
U.S. Pat. No. 4,160,971 discloses a passive transponder without a local power supply that is remotely powered by received transmissions. This device is primarily intended to measure pressure on dental plates. However, this device is intended to provide telemetry instead of a locator signal and it does not appear to be adapted for incorporation into denture that would be used for an extended period of time by an ordinary denture wearer. It also does not to be adapted for use with an existing denture.
Implants for use in a prosthesis are shown in U.S. Pat. No. 5,300,609 and in U.S. Pat. No. 5,855,909. However, these devices are also intended for data transmission instead of as a locator, and as such would not have the range to locate lost dentures.
A denture in accordance with the instant invention has base and teeth, including molar teeth, with a cylindrical glass encapsulated transponder embedded in the lingual flange of the denture adjacent molars mounted on the denture base. The transponder is covered by a denture material conforming to the contour of surrounding areas of the denture base, and the transponder emits a signal that can be remotely detected so that the denture can be found when lost.
The passive transponder can be mounted in a denture by forming a trench in a lingual area of a denture base adjacent molars on the dentures. The trench extends to a rear edge of the denture base. The transponder is then placed in the trench, and the trend is then filled to secure the transponder in the denture base.
This denture with a passive RF transponder can then be used in a system for locating a lost denture. The RF passive transponder contains an integrated circuit device connected to a coil. A reader having a transceiver for emitting an electromagnetic field is also used in the system. The electromagnetic field results in the generation of a voltage in the coil so that a code stored on the integrated circuit device is then transmitted through the coil to the transceiver for detecting the presence of a lost denture containing an RF passive transponder within a localized area.
FIG. 1 is a schematic view of a portable detection unit that would be used to locate a lost denture which includes a device emitting a signal in response to a field transmitted by the detection unit.
FIG. 2 is a view of the interior of a maxillary or upper denture showing an area in which a device can be mounted without adverse effects on the user's oral cavity or tongue.
FIG. 3 is a view of a representative passive device mounted in the palatal vault of a maxillary denture.
FIGS. 4A and 4B are views of another location in which another representative passive device can be located on the interior of the lingual flange area of a maxillary or upper denture.
FIGS. 5A and 5B are views of a cavity that can be located below the molar teeth area of a maxillary denture, and which can provide space for a representative passive signaling device.
FIGS. 6A and 6B are views of a representative device located on the lingual flange area of a mandibular or lower denture.
FIG. 7 is a view of a cavity in the molar teeth area of a mandibular denture in which a representative device responsive to an interrogation field can be located.
FIG. 8 is a view of another signaling device that can be mounted along one side of the lower denture.
FIG. 9 is a view of a passive signaling device including a magnetic strip whose presence can be detected by its response to variations in an external electromagnetic field, and also includes a number of other magnetic elements that can be used to deactivate the primary magnetic strip.
FIGS. 10A, 10B, and 10C are views showing the exterior of a representative insert or button that would be placed on a preexisting denture. FIG. 10A shows a roughened face of the insert that will be bonded to the denture. FIG. 10B shows a smooth surface on the opposite side that would be exposed and will conform to the shape of the denture. FIG. 10C is an edge view of the denture showing a shape that would correspond to the shape of a portion of the denture.
FIG. 11 is a view of two stationery transmitter-detector units that can be placed adjacent a trash or laundry facility or adjacent a door or entry into a trash or laundry area.
FIGS. 12A-C show the steps in forming a signaling or locating device using a magnetomechanical or magnetostrictive sensor element embedded in resin outer layers in which a gap or channel is formed between the sensor element and the resin layers by volumetric contraction of the resin as it solidifies.
FIG. 13 is a view of an RFID tag that can be mounted in a denture.
FIG. 14 is a view of a portable reader that can be used to locate an RFID tag, of the type shown in FIG. 13, embedded in a denture.
FIG. 15A is a view of an upper or maxillary denture in which a trough has been evacuated to receive an RFID, of the type shown in FIG. 13. FIG. 15B shows the same maxillary denture after the RFID tag has been embedded in the denture by refilling the trench to form a smooth denture surface.
FIG. 16A is a view of a lower or mandibular denture in which a trough has been evacuated to receive an RFID tag, of the type shown in FIG. 13. FIG. 16B is a view of the same mandibular denture after the RFID tag has been embedded in the denture by refilling the trench to form a smooth denture surface.
FIG. 17 is a view of a maxillary denture in which a magnetic conductive strip and an RFID tag have been embedded in different areas of the denture.
FIG. 18 is a view of a mandibular denture in which a magnetic conductive strip and an RFID tag have been embedded in different areas of the denture.
FIG. 1 is a schematic view showing basic components of a system for locating a denture that has been lost by a patient confined to a medical institution. This system includes a transmitter-detector unit or transceiver 2 which is capable of identifying a signaling device, here represented by device 50C, that is mounted on or included in the denture 10. In this representative embodiment, the transmitter-detector 2 emits an electromagnetic field or excitation field, represented by wave fronts 4, which impinge upon the signaling device 50C. The signaling device contains an internal component that is activated by the external electromagnetic field 4 and emits a signal, represented by return wave front 6 which is in turn detected by the detection circuit in the transmitter-detector 2. The strength of the excitation field 4 and the sensitivity of the signaling device 50C are chosen so that the lost denture 10 can be detected if the denture 10 is within a specified interrogation zone, represented by the boundary 8. Preferably this interrogation field has a radius of approximately three feet from the transmitter-detector unit 2 so that a suitable large area can be searched while still keeping the search area small enough to permit an effective search once the lost denture 10 has been detected within the search area. Although a search area having a radius of at least three feet is desirable, this invention is also applicable to systems having either larger or smaller search areas or interrogation zones. Portable transmitter detector units with an even more limited range can be employed because the searcher is mobile and can search a suspected area by placing the detector unit in close proximity to areas where the denture might be located. In a system that also employs stationary detector units, stationary detectors units can be used to monitor areas through which lost denture might be expected to pass, such as an exit to a garbage collection area. The portable units, even with very limited range, can be used to search specific areas, such as a room or closet, where there is a strong possibility that the lost denture might be found.
The preferred embodiment employs a passive signaling device 50 that emits a detectable signal only when subjected to a transmitted excitation field 4. Preferably this passive signaling device 50 does not include its own energy source, such as a battery, because a battery will increase the size of the passive signaling device 50 and a battery will have a finite life. In many cases a relative long time elapses between attachment of the signaling device 50 to the denture or incorporation of the signaling device 50 in the denture and the first time that the denture is lost. There may however be certain limited applications in which an active signaling device could be employed.
The transmitter-detector 2 depicted in FIG. 1 is intended to be a portable device that can be used to search several areas, such as different rooms in a medical institution. It should, however, be understood that stationary transmitter-detector units 2 would also be useful. For instance in a long term care facility a stationary unit could be located at the entrances and exits to dining facility, in laundry areas, in a trash disposal facility and near dishwashing facilities. When used in such applications the transmitter-detector units 2 should be activated only at certain times. For instance, when used in a dining area, the transmitter-detector 2 would be activated only when dishes and trays, where lost dentures 10 could likely be inadvertently placed, are removed from the dining area. This capability would limit false alarms as patients wearing dentures enter and exit the dining area. The transmitter-detector 2 is also not limited to devices in which both the transmitter and the detector are located within the same physical structure. Separate transmitter and detection units could also be employed. For example a transmitter could be located on one side of a doorway and the detector could be place on the opposite side. For portable units, one of two separate units could be located at one point while the other unit would be moved in a circle around the unit that is not moved. FIG. 1 shows only a single denture within the interrogation zone 8. However in many cases, both the upper and lower denture would be lost and by including signaling devices or locators or both dentures, the overall size of the locator could be greater than would be practical for a single locator of a size suitable for one denture, and therefore for some detection technologies, the size of the interrogation zone or search area could be larger.
Although signaling devices 50 could be embedded in a dentures when they are initially fabricated, the typical use of this system will be to detect previously fabricated dentures. This is especially true because the most frequent application of this device will be in a medical care facility, and most denture wearers will be fitted with artificial dentures long prior to entry into such a facility. FIGS. 2-7 show areas in which signaling devices 50 can be mounted on or encapsulated in either a maxillary or upper dentures 10 or mandibular or lower dentures 20.
FIG. 2 shows the lower or exposed area of a maxillary denture 10. The area 12 outlined at the rear of the denture 10 is located in the palatal vault area of the upper denture 10. If a signaling device 50 is mounted in this area, it will not irritate the oral cavity or the tongue of the denture wearer, provided that the signaling device 50 is not too thick and does not protrude substantially from the adjacent surface of the palatal vault area. A locator or signaling device 50 positioned within this area could have different shapes.
A signaling device 50A in the form of a button or insert having dimension of 3 mm�8 mm�40 mm could be located adjacent to and along the rear edge of the palatal vault area of the maxillary denture 10 in the manner shown in FIG. 3. This area would extend generally between the rearmost molars 14 on this upper denture 10. The thickness of this locator 50A would be less than the local thickness of the denture where the locator would be positioned. FIGS. 4A and 4B shows a signaling device 50B located along the interior lingual flange on one side of the maxillary denture 14. A signaling device 50B could also be located on the opposite side of the palatal vault area. A signaling device 50B having the dimensions of 7 mm�20 mm�2 mm could be located in this area. A device 50B located in this area could would be located along a flat surface of the posterior palate, but signaling device 50B cannot be allowed to intrude in the normal space for the dorsal side of the tongue and signaling device 50B cannot penetrate the palatal surface since this would cause irritation of the dense palatal tissue of the denture wearer. Both buttons 50A and 50B are shaped so that the exposed surface generally conforms to the local surface 18 of the denture 10, so that the button 50A can be firmly affixed to the denture without protruding too far into the denture wearer's oral cavity.
An alternative location for a signaling device 50 in the form of a button or insert is shown in FIGS. 5A and 5B where a signaling device 50C is located between the molar teeth and the gum surface of the maxillary denture. This location would be especially suitable for a denture in which the signaling device is positioned in the denture when the denture is initially manufactured in a dental lab.
Signaling devices can also be mounted on a mandibular or lower denture 20 as shown in FIGS. 6-8. The device 50D, shown in FIGS. 6A and 6B, is positioned on the lingual surface of the flange of the mandibular denture 20 in the base portion of the denture below the teeth.
FIG. 7 is another view of a button 50E located on the lower denture 20. This button 50E is located within a molar cavity 26 formed between lower molars 24 on one side of the denture 20 and the gum surface of the denture. As with the configuration shown in FIGS. 5A and 5B, material is removed from the denture behind the molars 24 to form the cavity 26. The signaling device 50E is then placed in the cavity 26 and a previously fabricated mold is used to restore the exterior surface of the molars 26.
FIG. 8 shows a third zone in which a signaling button 50F can be mounted on the lingual surface of the flange of the mandibular denture 20. It can be seen that the signaling button 50F is longer than the signaling button 50D shown in FIGS. 6A and 6B. FIG. 8 shows that some material can be removed from the lingual flange of the mandibular denture adjacent the front of the denture so that the button 50F will not protrude form the inner surface of the front denture at this location causing discomfort to the denture wearer.
FIG. 9 shows a passive magnetic strip 60 that is used in the preferred embodiment of this invention. These magnetic strips are commercially available from Sentry Technology Corporation and its subsidiary Knogo North America, Inc. and are referred to as Micro Magnetic strips. Micro Magnetic is believed to be a trademark of Sentry Technology Corporation. The magnetic strip 60 comprises two layers. The first layer 62 is a continuous thin strip formed from a soft magnetic material that has a relatively low coercivity so that the magnetic state of this strip 60 can be changed by the alternating magnetic field imposed by the varying electromagnetic field emitted by the transmitters in the transmitter-detector units. The second overlapping layer comprises a series of segments 64 that are formed from a second material that can occupy two different magnetic states. In one state, the low coercivity magnetic strip 62 is unaffected by the segments 64. When the segments 64 are in a second magnetic state, the magnetic field exerted by the segments 64 effectively prevents any changes in the magnetic state of the strip 62. Since the magnetic state of the strip 62 remains constant, no detectable signals are emitted by the strip 62 in response to a varying magnetic field to which the magnetic strip 60 is subjected. In one version of magnetic strips of this general type, the segments 64 can be magnetized so that the magnetic field exerted by the segments 64 is larger than the peak magnetic field exerted by the incident electromagnetic field on the strip 60. Thus the incident magnetic field is not strong enough to change the state of the soft magnetic material in strip 62. In alternative magnetic devices of this type, the magnetic field exerted by the second segments or strips on the variable magnetic strip, will bias the primary magnetic strip so that a distinctive response will be generated.
The segments 64 can be activated and deactivated by a separate apparatus that can be used to change the magnetic state of the segments 64 between an active and an inactive state. Typically the segments would be placed in a state corresponding to a device inactive state when the denture wearer would not be residing in a medical care facility to prevent inadvertent activation of transmitter-detector units that might be used for other purposes. The magnetic device 60 would be activated when the denture wearer is in a health care institution equipped with transmitter detector units to prevent inadvertent loss by the denture wearer. A system of this type would therefore permit installation of a signaling device 50 in a denture before the denture wearer moves to a health care facility. Of course this description applies to only one representative embodiment of magnetic strip signaling units that can be employed with this invention. For instance harmonic magnetic strips can be employed in addition to other configurations in which the magnetic field in altered when in the presence of a varying electromagnetic field.
There are a number of different materials that can be employed to fabricate the magnetic strip 62, or their equivalents, and the secondary segments 64, or their equivalents. Permalloy is one material that has been used for the primary magnetic strip, such as strip 62. Other similar strips use a material marketed by Allied Signal or Honeywell under the trademark Metglas. U.S. Pat. No. 5,029,291 discloses a cobalt alloy that can exhibit an asymmetric hysteresis characteristic and the response can be detected when subjected to a variable incident magnetic field. One material that can be used to form the segments 64 is iron oxide. Other material for fabricating magnetic detector strips of this type are also known to those of ordinary skill in the art.
FIGS. 10A through 10B show a dental locator strip 50 that employs the magnetic strip 60. The dental locator strip 50 includes a resin layer that encapsulates the magnetic locator strip 60 to protect both the denture wearer form the magnetic locator strip 60 and the strip form the acids or other contaminates that may be present in the denture wearer's oral cavity of from fluids that may be used to clean the denture. The resin used in the dental locator 50 can comprise a resin of the type typically used in dentures. The preferred embodiment of this invention employs methyl methacrylate as the resin surrounding the magnetic locator strip 60. The methyl methacrylate also serves to bond the dental locator 50 to the denture. An alternate material is (2-2-bis(4-(2-hydroxy-3-methacryloyloxy propoxy)phenyl)propane, commonly referred to as bis-GMA. Neither of these resins is ferromagnetic and the electromagnetic field can penetrate either resin so that the magnetic strip 60 will still be subjected to the incident variable electromagnetic field.
The interior side 54 of the dental locator strip 50, shown in FIG. 10A would either have a generally rough texture, or would be roughened prior to attachment to the denture so that the resin can be bonded to the denture. FIG. 10B shows the exterior smooth surface 52 of the dental locator 50 that will be exposed when the dental locator is bonded to the denture. This surface 62 will have a contour that will confirm to the local contour of the denture to which the dental locator 50 will be bonded. FIG. 10C shows that the exterior surface 52 will have a generally concave contour, although the precise shape of each dental locator 50 will conform to the local contour of the individual denture. The manner in which this shape is formed will be subsequently discussed in greater detail.
The exterior surface 52 of dental locator 50 also includes a visible indicia that will enable a lost denture to be identified when found. A representative bar code 58 is visible on surface 52. This bar code 58 will serve as a unique identifier for both the denture and the denture wearer so that a lost denture can be returned to its owner. In the preferred embodiment of the system of which each dental locator 50 is a part, a central database, including all dentures and denture owners, will be maintained. Of course individual databases could also be maintained at each health care institution.
Irrespective of the type of signaling component used in the signaling device 50, the device can be mounted on an exposed surface of an existing denture in the same manner. First the dental surface to which the signaling button 50 is to be attached is to be cleaned and sterilized. A groove or trench is then cut into the denture. This groove or trench is large enough to at least partially insert the dental locator 50 so that the exposed surface 52 will be substantially flush with the local contour of the denture when bonded to the denture. The surface of the locator zone or trench must then be primed with a liquid monomer of the acrylic that is used to encapsulate the dental locator strip. In most cases the material encapsulating the internal component will be methyl methacrylate, which is available as a liquid monomer and as a polymer powder. A liquid paste of monomer and polymer of the acrylic resin of the denture base and the capsule will be applied to the prepared denture and the previously roughened surface 54 of the dental locator strip 50. The dental locator will then be placed in the prepared zone and cured and finished in a smooth and polished surface in accordance with standard denture finishing procedures. Dentures and dental locators fabricated from methyl methacrylate can be cured in hot water and a chemical bond will be formed between the denture and the button. The button 50 will then be permanently bonded to an external surface of the denture in a location where the denture will not excessively protrude from the surrounding contour of the denture and will not cause discomfort to the denture wearer.
The visible mark, such as the bar code 58, shown in FIG. 10A can be used to identify the owner of each denture after it is found. Such a unique mark can be stored on a computer stored and accessible database which could include information in addition to the identify of the owner. Such an approach would permit entry of information to the database in a manner that the personnel at a medical institution would find familiar and would not require an special procedure for encoding an integrated circuit component or other codeable component. If such information is stored on a computer accessible database, that information can be made available to other institutions. For example if the database is accessible via the INTERNET or via a similar network, other institutions can easily access the information. For example if a nursing home patient is transferred to a hospital, where the denture is lost, the hospital can access data entered at the nursing home to identify the owner of a lost denture after it is found. Furthermore the database can include information that would permit a dentist to fabricate a new denture if the original is damaged beyond repair.
FIGS. 12A-C show the manner in which the marker element 100 can be embedded in methyl methacrylate, a material suitable for use in a denture without adversely affecting the mechanical vibration of the magnetomechanical target, especially a magnetic strip exhibiting vibrations due to the Barkhausen effiect. The first step in this example is to deposit a first layer 102 methyl methacrylate by mixing a liquid monomer with a polymer powder which are mixed in accordance conventional dental procedures. The layer can be deposited in a mold or on a surface or sheet having the same contour as the denture surface on which this signaling device or locator 110 is to be mounted. This layer is deposited in a concentration such that the methyl methacrylate has a soupy consistency. After the first layer of methyl methacrylate is deposited, the target 100 is positioned on the upper surface of this lower layer 102. The lower layer 102 extends beyond the marker 100 on all four lateral sides of the marker 100. The next step in this process is to deposit an upper layer 104 of methyl methacrylate on top of the marker 100. This upper layer 104 can be formed in the same manner as the lower layer 102 by mixing the liquid monomer with the liquid polymer. The upper layer 104 can be initially deposited on a second surface having a shape that will conform to the shape of the lower layer 102. The upper layer 104 is then positioned on top of the marker 110 and in contact with the lower layer 102. The upper layer 104 completely covers the upper surface of the marker 100 and extends beyond it on all sides. The upper layer 104 is also in contact with the lower layer 102 on all four sides so that the upper layer 104 can bond to the lower layer 102 on all four sides. The marker 100 will then be completely isolated, and will not come into contact with the oral cavity of the denture wearer when the locator element 110 is mounted on a denture.
The next step, illustrated in FIG. 12B is to apply pressure to the composite structure before the two layers 102 and 104 of methyl methacrylate polymerize to form a solid structure. Note that some of the methyl methacrylate material is permitted to laterally extrude as the composite structure is flattened and its thickness reduced. It has been demonstrated that a locator element or button 110 having a thickness of 1.30 mm (0.0510 inch) can be fabricated in this manner. The polymerization reaction between the liquid monomer and the power polymer, the constituents from which the methyl methacrylate structure is formed, will continue for both the upper layer 104 and the lower layer 102 until the composite structure solidifies.
Even though the fully polymerized methyl methacrylate in its solid form completely surrounds the magnetic marker, the magnetomechanical material 108 can still vibrate about its resonate frequency because a gap or channel 112 separating the magnetic material 108 from the solid layers 102 and 104 can be formed as illustrated in FIG. 12C. As the polymerization of the methyl methacrylate is completed and it solidifies, the methyl methacrylate will shrink due to the volumetric contraction which occurs during this reaction. The volume of solid polymer methacrylate material is less than the volume of the constituent liquid monomer and powder polymer that form this material. Thus the methyl methacrylate material will tend to shrink away from the embedded target 100 forming the gaps 112, because the methyl methacrylate will not adhere to the plastic material surrounding the magnetic material 108. The size of these gaps or channels 112 is not shown to scale in FIG. C, which is intended to be a schematic illustration only. The two layers 102 and 104 surrounding the strip 100 will not shrink away from each other or separate because they will form a bond as the material cures. In this manner, the strip 100 can be surrounded by a material that is suitable for use in a denture, but the vibration of the magnetomechanical material will not be adversely affected. This approach is believed to be of special importance with magnetic strips in which large mechanical stresses are induced in the magnetic material to enhance the detectable signal.
After the composite structure of the locator or signaling device 110 is formed in this manner, the outer resin layer can be trimmed to size. When installed in a denture, one exterior surface of the composite structure will be roughened and more liquid methyl methacrylate will be applied to bond the signaling device 110 to an exterior surface of the existing denture. Alternatively a roughened surface on a surface of one of the two layers can be formed by depositing the liquid and powder constituent materials on an external surface or in a mold having a roughened contour. Although the preferred embodiment depicted in this example is flat, it should be understood that the composite signaling device can be formed with a curvature that is suitable for securing the device 110 to the contour of a surface of the denture.
FIG. 11 shows stationery transmitter-detector units 120 and 122 that can be used to detect the strips 100 or 110. These stationery transmitter-detector units 120 and 122 are commercially available from Sentry Technology Corporation, and its subsidiary Knogo North America, Inc. and are referred to as Knoscape Micro Magnetic detection panels. Knoscape and Micro Magnetic are trademarks of Sentry Technology Corporation. Each of the transmitter-detector units 120 and 122 are both transmitters and detectors and can be positioned adjacent to a door or entry into a trash or laundry facility or area or any other area where dentures might be inadvertently lost. These transmitter-detector units can also be located adjacent to the trash receptacle or to the laundry apparatus. Two transmitter-detector units 120 and 122 of this type can be positioned at least three feet apart and they are joined by a low power cable 124. One of the units is attached to a standard electrical outlet, and an electronics box, not shown, containing suitable detection circuitry will be connected to the transmitter-detector units which serve as antennas. It has been found that denture units with targets 100 can be detected when large trash receptacles are rolled between transmitter-detector units 120, 122. Denture units with targets 100 attached can also be detected when a box containing the denture unit is thrown between the units 120, 122.
The magnetic locator strips shown in FIGS. 1-12 are not the only markers or tags that can be used to locate lost dentures. A radio frequency identification tag 200 is shown in FIG. 13. This tag 200 can be detected by a reader or detector 210 as shown in FIG. 14. FIGS. 15A and 15B show the manner in which one of these RFID tags 200 can be used with an upper or maxillary denture 220. FIGS. 16A and 16B show the manner in which the RFID tags 200 can be used in a lower or mandibular denture 230. The RFID tag 200 can also be used with a magnetic strip 50B in a maxillary denture as shown in FIG. 17 or with a magnetic strip 50D as shown in FIG. 18.
The radio frequency or RFID tag or passive transponder 200 shown in FIG. 13 includes an integrated circuit chip 206 that is connected to a coil or inductor 202, which surrounds a ferrite core 204. This subassembly is then encapsulated by a glass tube or envelope 208 which isolates the electronic subassembly from the surrounding environment, or conversely is suitable for protecting the vessel or the animate object with which the tag or transponder 200 is used. When the passive transponder 200 is placed in an electromagnetic excitation field generated by a reader or interrogator, such as portable reader 210, energy is inductively coupled through the coil 202 to power the integrated circuit component 206. The integrated circuit 206 comprises a logic component that when energized transmits a steam of pulses to the coil 202 which can in turn be detected by the reader 210. The pulses emitted by the logic component or integrated circuit chip 206 can either be in the form of a signal that is unique to each chip 306 or one that is more readily detectable by the reader 210. A unique ID number can be individually inscribed and programmed on the microchip 206 in the form of an alphanumeric identification code. Transponders of this type are manufactured by a number of different companies including Destron, Avid, Trovan, Nedap, Datamars, and Texas Instruments. These commercial transponders typically transmit an identification signal consisting of a string of ones and zeros in a number of different formats including FSK and PSK bit coding with Manchester and NRZ data encoding at bit rates ranging from 2500 BPS to approximately 8 K BPS. Transmit frequencies on the order of 125 kHz are common. The transmission of data between transponders 200 and readers 210 is described in more detail in U.S. Pat. No. 5,952,935, which is incorporated herein by reference. Transponders of this general type are also described in European Patent Specification 258 415.
The reader 210 used to locate the transponder 200 employs an antenna 212 and suitable transceiver electronics to both transmit an electromagnetic field at an appropriate excitation frequency and to detect the response from the transponder 200. The reader 210, shown in FIG. 14 is described in more detail in U.S. Pat. No. 5,952,935, which is again incorporated herein by reference. Battery powered reader or detector 210 also includes an on-off switch 214. When a response is received from the transponder 200, an ID number is displayed on an LCD 216. The reader also includes a data port 218 for transmitting data to other data processing equipment, such as a computer. Port 218 can be an RS 232 or EIA232 port.
Transponders 200 are available in different sizes. One commercially available transponder has a length of approximately 8-10 mm. Another transponder has dimensions of 18 mm by 3.5 mm. The smaller transponder can, at least in some circumstances, be detected at a range of up to 12 inches. The larger transponder can be detected, at a distance of 18-20 inches. These transponders or RFID tags conform to current ISO 11784 and ISO 11785 standards for B-Type devices. The transponders 200 can be detected by a representative transceiver or detector 210, shown herein as manufactured by Destron Fearing and referred to as the Pocket Reader EX� model. This particular version is not believed to be capable of detecting the transponder 200 at the maximum extent of these ranges. However, other hand held portable readers or scanners that are also available from Destron Fearing employ a larger antenna and is believed to have a greater range. An 18 mm by 3.5 mm microchip tag embedded in a denture has been detected at range of from 8-12 inches using a 2001F Portable Reader also manufactured by Destron Fearing. Stationary units are also available that have a greater range and it is believed that transponders of this type can be detected within a 24 inch by 24 inch area. Stationary units capable of maximum range are comparatively expensive and are therefore not believed suitable for use in locating lost dentures within a rest home, hospital or other medical or health care institution.
Transponders 200 can be embedded in existing maxillary and mandibular dentures. They can also be embedded in dentures during the original construction of the dentures. FIGS. 15A and 15B show one way in which a transponder 200 can be embedded in a maxillary or upper denture. The thickest portion of the base of a maxillary denture 220 is along the lingual surface on the interior of the molars 222. A trench 224, have a depth and length sufficient to accommodate a transponder 200 can be evacuated along this surface of the denture using conventional tools. The transponder 200 can then be positioned in this trench 224 and denture material such as methyl methacrylate. The filled area can then be smoothed to conform to the original contour of the lingual flange of the 220 denture with the transponder completely embedded in the denture 220. The methyl methacrylate used to fill in the trench 224 and to surround the transponder can be the same color as the rest of the denture so that the transponder will not be as visible as if a clear acrylic had been used, although the outline of the transponder can still be seen so that it can be located for scanning, and a person who finds the denture, when lost, can see that it bears an identifying transponder 200.
Although it is preferred that the transponder 200 be embedded on the interior or along the lingual flange of the maxillary denture, the transponder 200 can also be embedded along the exterior portion of the denture below the molars and adjacent the rear of the denture or adjacent the portion of the denture adjacent to the rear molars. It is possible to embed either the smaller 8-10 mm transponder or tag or the larger 18 mm by 3.5 mm transponder or tag in this area.
One technique for positioning the transponder 200 in the trench 224 is to use a syringe to place the transponder 200 in the trench 224. At least some commercially available transponders of this type are packaged in a syringe. Evacuating the trench 224 to the rear end of the maxillary denture 220 simplifies use of the syringe to place the transponder 200.
FIG. 16A shows the position of a trench 234 in a mandibular or lower denture 230. Here to the trench 234 is located on one lingual surface adjacent to molars 232. For mandibular dentures 230 this area is also the thickest part of the denture base. Trench 234 is also evacuated to a depth and length sufficient for placement of a transponder 200, and the trench extends to the rear edge of denture 230 to simplify placement of the transponder 200 using a syringe. FIG. 16B shows the same mandibular denture after the transponder 200 has been covered by dental acrylic.
The transponder 200 can be easily installed or embedded in a denture in not more than 15 minutes. This includes the step of evacuating the trench or channel followed by the steps of filling the trench or channel with dental acrylic or other suitable material and smoothing the dental acrylic to conform to the surrounding denture. This also includes the time for completion of the polymerization reaction so that the newly deposited material will have essentially the same characteristics as the original denture material. Of course this last step does not require involve a dentist or a dental technician, who is then free to attend to other matters.
The transponder 200 provides a simple method of identifying the specific denture when it is found. The unique code stored in the memory of the integrated circuit can be recorded or cross referenced on a database maintained either locally or on a network accessible database or through the Internet. The portable detector 210 can also be used as a locating device for a denture containing a transponder 200. Although the detectable range may differ, in some cases portable detectors of the general type represented by scanner 210 can be used to detect transponders at a range of 6-8 inches. Perhaps more common is a range of approximately 2 inches. Even this range can be sufficient to find a denture that may have been lost in bed linens, on table tops or under garments in a closet. A portable scanner 210 can also be used to further isolate and find a denture that has been located with a garbage container. In other words, areas where there is a high likelihood that a denture may have been lost can be scanned using the portable detector 210, even with limited range. Short range portable detectors of this type can be especially useful in rest homes or nursing homes, where the denture wearer would commonly not venture from a relatively limited area. The portable detector could still be used for other purposes, for example to locate lost orthodontic devices.
FIGS. 17 and 18 show that a transponder 200 can also be used in conjunction with a magnetic strip 50B in a maxillary denture 10 or with a mandibular denture 20 containing a magnetic strip 50D. In these views the transponder 200 is located on the opposite side of the denture base from the magnetic strips 50B and 50D. Alternatively, both locating tags could be located along the same side. Neither of the two locating tags cause interference that would prevent detection of either tag by the detectors or scanners use separately. This configuration would allow use of a magnetic strip detector that has more range than one of the portable detectors 210 to find lost dentures at a relatively long range. Thus a magnetic strip detector located near a garbage disposal area, or in a laundry or in a kitchen could be used to alert a worker that a denture containing a magnetic strip is present in a large bag or a collection of dirty dishes. A portable scanner or reader 210 could then be used to locate a transponder 200 at closer range, thus eliminating the need to conduct a hand search or all of the garbage or soiled material within a bundle. It is believed that the use of the two separate passive tags or locators is more cost effective. Although transponders 200 may be detectable at the same distance as magnetic strips, the cost of stationary scanners or detectors have the ability to locate transponders as they pass through a doorway may be prohibitive. It may also be necessary to drive scanners for transponders 200 at such an intensity that interference and other problems may be created. Other magnetic components, such as rare earth magnets, can also be detected in the presence of a varying electromagnetic fields, and such devices, which have been used in dentures for other purposes, can increase the detection range.
The magnetic strips and RF transponders depicted herein can also be used to locate other devices, such as eyeglasses and hearing aids, as part of a complimentary system suitable for use in medical and health care institutions.
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Originally written on Pro Sports Daily | Last updated 7/12/12
PITTSBURGH - JANUARY 21: Forward Alexander Semin #28 of the Washington Capitals waits for a face off against the Pittsburgh Penguins on January 21, 2010 at Mellon Arena in Pittsburgh, Pennsylvania. (Photo by Jamie Sabau/Getty Images)
For the past six seasons, the Washington Capitals have counted on Alexander Semin to provide most of their offense from the wing, and he has obliged with 187 goals. Now that they've cut ties with the enigmatic winger, the Caps are hoping free agent acquisition Wojtek Wolski will supply the missing offense. Ironically, Wolski has drawn less-than-flattering comparisons to Semin. Like Semin, Wolski is a first-round draft pick who came into the NHL with great promise, only to fall short of expectations in recent seasons. Semin's goal totals dropped from 40 in 2009-10 to 28 the following year and 21 last season. Wolski's goal totals dropped from a career-high of 23 in 2009-10 to 12 the following year and four last season. That's why he was willing to sign a one-year contract with the Capitals for $600,000, just $100,000 above the NHL minimum. By comparison, Wolski just completed a two-year contract worth $7.6 million. "I had one bad year, and this year was tough with the (sport...
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The AKG KM211/1 Telescoping Boom Arm (Black) is K&M's classic 2-piece telescopic boom arm with 3/8" thread, featuring their non-marring height-adjustment mechanism. The KM211/1 extends from 18.5 to 30.31".
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