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Medical Biostatistics for Complex DiseasesHardback
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- Publisher: Wiley-VCH Verlag GmbH
- Format: Hardback | 412 pages
- Dimensions: 178mm x 246mm x 26mm | 898g
- Publication date: 15 June 2010
- Publication City/Country: Weinheim
- Illustrations note: 100 schwarz-weiße und 50 farbige Abbildungen
- Sales rank: 2,027,148
Product description
A collection of highly valuable statistical and computational approaches designed for developing powerful methods to analyze large-scale high-throughput data derived from studies of complex diseases. Such diseases include cancer and cardiovascular disease, and constitute the major health challenges in industrialized countries. They are characterized by the systems properties of gene networks and their interrelations, instead of individual genes, whose malfunctioning manifests in pathological phenotypes, thus making the analysis of the resulting large data sets particularly challenging. This is why novel approaches are needed to tackle this problem efficiently on a systems level. Written by computational biologists and biostatisticians, this book is an invaluable resource for a large number of researchers working on basic but also applied aspects of biomedical data analysis emphasizing the pathway level.
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Author information
Frank Emmert-Streib studied physics at the University of Siegen, Germany, and received his PhD in theoretical physics from the University of Bremen. He was a postdoctoral research associate in the department for Bioinformatics at the Stowers Institute for Medical Research in Kansas City, USA, and a senior fellow in the departments of Biostatistics and Genome Sciences at the University of Washington, Seattle, USA. Currently he is an assistant professor at the Queen's University Belfast at the Center for Cancer Research and Cell Biology, leading the Computational Biology and Machine Learning group. Frank Emmert-Streib's research interests are in the field of computational biology, biostatistics, network biology and machine learning, focusing on the development and application of methods to analyze high-dimensional, large-scale data from molecular biology. Matthias Dehmer studied mathematics at the University of Siegen, Germany and received his PhD in computer science from the Darmstadt University of Technology. Following this, he was a research fellow at the Vienna Bio Center, Austria, and at the Vienna University of Technology. He is currently an associate professor at UMIT - The Health and Life Sciences University in Hall in Tirol, Austria. His research interests are in bioinformatics, systems biology, complex networks, statistics and information theory. In particular, Matthias Dehmer is working on machine learning-based methods to design new data analysis methods for solving problems in computational and systems biology.
Table of contents
Preface (Emmert-Streib and Dehmer) GENERAL BIOLOGICAL AND STATISTICAL BASICS The biology of MYC in health and disease: a high altitude view (Turner, Bird and Refaeli) Cancer Stem Cells - Finding and Hitting the Roots of Cancer (Buss and Ho) Multiple Testing Methods (Farcomeni) STATISTICAL AND COMPUTATIONAL ANALYSIS METHODS Making Mountains Out of Molehills: Moving from Single Gene to Pathway Based Models of Colon Cancer Progression (Edelman, Garman, Potti, Mukherjee) Gene-Set Expression Analysis: Challenges and Tools (Oron) Hotelling's T-2 multivariate profiling for detecting differential expression in microarrays (Lu, Liu, Deng) Interpreting differential coexpression of gene sets (Ju Han Kim, Sung Bum Cho, Jihun Kim) Multivariate analysis of microarray data: Application of MANOVA (Hwang and Park) Testing Significance of a Class of Genes (Chen and Tsai) Differential dependency network analysis to identify topological changes in biological networks (Zhang, Li, Clarke, Hilakivi-Clarke and Wang) An Introduction to Time-Varying Connectivity Estimation for Gene Regulatory Networks (Fujita, Sato, Almeida Demasi, Miyano, Cleide Sogayar, and Ferreira) A systems biology approach to construct a cancer-perturbed protein-protein interaction network for apoptosis by means of microarray and database mining (Chu and Chen) NN, title not confirmed (Fishel, Ruppin) Kernel Classification Methods for Cancer Microarray Data (Kato and Fujibuchi) Predicting Cancer Survival Using Expression Patterns (Reddy, Kronek, Brannon, Seiler, Ganesan, Rathmell, Bhanot) Integration of microarray data sets (Kim and Rha) Model Averaging For Biological Networks With Prior Information (Mukherjeea, Speed and Hill)


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Jackfruit Seed Aviyal
This recipe is a healthy recipe as Jackfruit seeds being a main ingredient in it. Jackfruit seeds would give you around 135 kcal/100 gms. It is a rich source of complex carbohydrate, dietary fiber, vitamins like vitamin A, C and certain B vitamins, and minerals like calcium, zinc, and phosphorous. They contain lignans, isoflavones, saponins, that are called phytonutrients and their health benefits are wide-ranging from anti-cancer to antihypertensive, anti-ageing, antioxidant, anti-ulcer, etc. Jackfruit seed powder has the ability to relieve discomfort due to indigestion. Boiled Jackfruit seeds are a very tasty and nutritious snack. Boiled Jackfruit seeds can be used as an alternative to potatoes. Jackfruit seeds, which appeal to all tastes, may be boiled or roasted and eaten, or boiled and preserved in syrup like chestnuts. They can be canned in brine, in curry, and, like baked beans, in tomato sauce. They can also be included in curried dishes. Roasted, dried seeds are ground to make flour which is blended with wheat flour for baking.
|Jackfruit seeds
|1 Cup (16 tbs), sliced
|3 Tablespoon
|1 Teaspoon
|Garlic pod
|1 Small
|Green chillies
|Turmeric powder
|1⁄2 Teaspoon
|2 Teaspoon
|Mustard seeds
|1 Teaspoon
|Urad dal
|1⁄2 Teaspoon
|2 Tablespoon
|To Taste
Grind coconut, jeera, garlic, small onion, curry leaves, green chillies and turmeric powder into coarse paste.
Peel the jackfruit seeds and slice them. If need be used frozen jack fruit seeds, which comes sliced. In a pan, cook jackfruit seeds with salt and just enough water. Once seeds are half cooked add the coconut paste. Cook well till the raw smell goes. In a pan, heat oil and fry mustard seeds, urad dal and curry leaves. Pour these into the seed mixture. Switch off the heat and now add yogurt and mix well. Serve with rice and sambhar.
Recipe Summary
Difficulty Level:Medium
Course:Side Dish
Preparation Time:15 Minutes
Cook Time:30 Minutes
Ready In:45 Minutes
StoryThis dish possibly would have originated by Kerala Iyers. The principle underlying is the use of several vegetables as are available, boiling them together with a souring agent, add ground coconut along with green chilies and later seasoning with raw coconut oil. Depending on different areas of Kerala the souring agents differed. Some of the common souring agents were tamarind, buttermilk and mango. There is a story that the Great Ramaiyan Dalawai formulated this dish when he was employed in the Ootupurai (free mess for brahmins) of Travancore king. In Travancore a special Aviyal is prepared using red amaranth leaves, mango, drumstick and jackfruit seeds.
Jackfruit Seed Aviyal
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Jackfruit Seed Aviyal Recipe, Jackfruit Seed Aviyal

subset: commoncrawl


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Rank #415 on SubscribersLevel 317 Comments: Wizard
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What do you think? Give us your opinion. Anonymous comments allowed.
#13 - pleuradispensor (03/18/2015) [-]
is there ever going to be another installment of "weird **** my rommate does?"
#15 to #13 - chuffberry (03/19/2015) [-]
i didn't know if i should make another one or not. i've been on spring break, so i can post a new one in a few days.
#16 to #15 - pleuradispensor (03/19/2015) [-]I very much enjoyed the first ones
#14 to #13 - pleuradispensor (03/18/2015) [-]
**pleuradispensor used "*roll Magic 8-Ball*"**
**pleuradispensor rolls Cannot predict now**
**pleuradispensor rolls Cannot predict now**
#10 - orgrok ONLINE (03/03/2015) [-]
Is your roommate actually Jewish? If she just claims she is without being born jewish, or properly converted, shes still goy. - A jew
#11 to #10 - chuffberry (03/03/2015) [-]
i'm not entirely sure. i think she is jewish, because she refers to non-jews who date jews as "goy toys".
#9 - oriphiel (03/02/2015) [-]
kelly sounds absolutely awful, you should post a picture of her so we know if she fits the stereotype feminazi image
#8 - arena ONLINE (03/01/2015) [-]
Kelly doesn't sound to nice. How long have you been living with her.
#2 - Spavaloo (09/22/2012) [-]
I find your idiocy regarding Ancient Greek creation myths to be personally offensive.
#1 - thatnerdyguy (07/20/2012) [-]
No comment virginity will be left untaken.
#4 to #1 - rainbowkindness (02/20/2014) [-]
Look back at this comment and look at the date. How much has things changed?
#5 to #4 - thatnerdyguy (02/20/2014) [-]
Well, I still enjoy getting the first comment on a page, simply for the sake of having it. I've changed in a lot of ways, but that is not one of them.
#6 to #5 - rainbowkindness (02/20/2014) [-]
Ah, was not meaning to seem to have that intent. Just sometimes it's nice to look back on old stuff. I know when I do I can usually remember somewhat what happened that day and I can compare to my average day now.
#7 to #6 - thatnerdyguy (02/20/2014) [-]
Yeah, I gotcha. It's pretty weird looking back on some old comments.


text:
The amounts of "material unaccounted for" were classified by the AEC.
Using this device he was able to store hundreds of thousands of classified documents in decrypted form.
He put American and other lives at risk with some of his 2010 leaks of classified military material.
"arranged in classes," 1828, past participle adjective from classify. Meaning "secret" (of government information) is from 1941, American English. Classifieds (n.) "newspaper advertisements arranged by classes," 1913, is short for classified advertisements
1782, from French classifier, from classe (see class (n.)) + -fier (see -fy). Related: Classified; classifying.


text:
Advent Introit and Amen
By Ralph Manuel
Advent Introit and Amen composed by Ralph Manuel. For SATB choir, keyboard. Advent, Gathering/Processional. Moderately Easy. Octavo. Published by MorningStar Music Publishers (MN.50-0042).
This anthem helps us affirm our faith in God and his promises, and comforts us with the reminder that soon God's Anointed will come. As you sing this anthem, imagine God's smile as he embraces us in his arms and tells us of the peace that awaits us.


text:
I'm running os x lion. A version of ruby was installed when I installed the OS. I then installed RVM and then installed ruby 1.9.2 and made it the default for new shells.
Default Ruby (for new shells)
ruby-1.9.2-p290 [ x86_64 ]
What happend to the older version of Ruby that was already on my system and how can I remove it since RVM doesn't see it?
When I try to use the new hash syntax in code written in textmate or sublime text 2 it fails. When the same code is run in the shell it works. So how do I make ruby 1.9.2 the only ruby installed on my system?


text:
I am from India.
A new version of the ZTE tab has been launched here as Reliance 3g Tab.
It is a Android 2.3.4 but it is not supporting Flash Player..
I searched on net and it is saying that tablet has 800Mhz processor so its not supporting.
Details about the tablet:
Model number: V9C
Android version: 2.3.4
Baseband version: V9CB01
Kernel version: 22.214.171.124-perf+zte-kernel@Zdroid-SMT
Build number: GB_RLNC_V9CV 1.0.0B03
Anyone plz help how to get the flash player work on the websites
Edited by Jayshree, 07 December 2011 - 09:13 AM.


text:
Leicester Tigers v Sale Sharks - Aviva Premiership match preview
Last Updated: 02/03/13 2:20pm
Tom Croft will captain Leicester Tigers in the Aviva Premiership fixture against Sale Sharks at Welford Road this Saturday.
Back-rower Croft has made a successful return after a neck injury in recent weeks and makes his 100th starting appearance for the club this weekend.
Mathew Tait and Niall Morris return to the backline for Saturday - Leicester's only home fixture during March - while Thomas Waldrom returns from the England squad to take the Tigers No8 shirt.
Tigers are without six players retained by England this weekend, while Anthony Allen, Miles Benjamin, Martin Castrogiovanni, Louis Deacon, Geordan Murphy and Boris Stankovich are unavailable due to injury.
Meanwhile, Sale Sharks travel to Welford Road to play Leicester hoping to bounce back following the 21-30 defeat at home to high-flying Harlequins last Friday.
The Sharks have won their last two away games in all competitions but have not won three in a row on the road in the same season since October 2006.
Scrum-half Will Cliff signed a new deal at the club earlier in the week but is unavailable against the Tigers due to an injury sustained in a freak training ground incident.
Leicester Tigers: 15 Mathew Tait, 14 Niall Morris, 13 Matt Smith, 12 Dan Bowden, 11 Adam Thompstone, 10 George Ford, 9 Sam Harrison, 8 Thomas Waldrom, 7 Julian Salvi, 6 Tom Croft (c), 5 Graham Kitchener, 4 Ed Slater, 3 Logovi'i Mulipola, 2 Rob Hawkins, 1 Marcos Ayerza.
Replacements: 16 George Chuter, 17 Kieran Brookes, 18 Fraser Balmain, 19 Brett Deacon, 20 Jordan Crane, 21 Micky Young, 22 Matt Cornwell, 23 Scott Hamilton.
Sale Sharks: 15 Cameron Shepherd, 14 Tom Brady, 13 Jonny Leota, 12 Sammy Tuitupou, 11 Will Addison, 10 Nick Maclod, 9 Cillian Willis, 8 Richie Vernon, 7 David Seymour (c), 6 Dan Braid, 5 Fraser McKenzie, 4 James Gaskell, 3 Henry Thomas, 2 Marc Jones, 1 Ross Harrison.
Replacements: 16 Tommy Taylor, 17 Al Dickinson, 18 Tony Buckley, 19 Richie Gray, 20 Andy Powell, 21 Nathan Fowles, 22 Danny Cipriani, 23 Jordan Davies.
What they said...
Leicester boss Richard Cockerill
"We've had disappointing results in the last two weeks but in terms of performance we've done some good things," said Cockerill.
"There are still six games remaining so there is a lot of rugby to be played yet and a lot of points still up for grabs. We keep a positive frame of mind and just keep battling away."
Sale wing Will Addison
It's a big game away at Leicester this weekend but they have lost a few players to international call-ups," said Addison.
"We showed what we can do at Welford Road last year and picked up a losing bonus point down there. It's a big ask to go to Leicester and win but if we can bring the different parts of our game together we feel we can do well.
"The important thing to remember is that there are still six games left and a lot of rugby to be played."
Aviva Premiership 2012/13 Round 17
Premiership Round 17
We look back at some of the best images from Round 17 in the Aviva Premiership.
McCall hails winger Strettle
Mark McCall praised winger David Strettle, a try-scorer in Saracens' 35-14 victory over London Welsh on Sunday
Sarries beat Exiles to go top
Saracens took full advantage of Harlequins' slip-up by beating London Welsh 35-14 to return to the top of the table.
- Mallinder's tip for Lancaster
- O'Shea frustrated by defeat
- Cockerill: Croft for England
- Mighty Chiefs take charge
- Elliott the hero for Saints
- Leicester hit Sale for six
- Booth savours derby victory
- Worcester display pleases Hill
- Worcester claim Wasps upset
- Heathcote keeps Bath believing
- Fiddes' Cent
- Quins v Exeter: Teams
- Saracens v L Welsh: Teams
- Northampton v L Irish: Teams
- Worcester v Wasps: Teams
- Bath v Gloucester: Teams
- Timely lift for Steenson
- Bragging rights
- Hopper: No time to relax


text:
Release Date:
August 22, 2006
Released just before his first album for the Gospo Centric label, The Definitive Collection is an overview that covers Dave Hollister's first four solo albums, and it also includes two of his spotlight roles with Blackstreet ("Before I Let You Go," "Falling in Love Again") and one with Force One Network ("Spirit [Does Anybody Care]," from the Boyz N the Hood soundtrack). There can't be a great deal of demand for this disc; Hollister has his followers, most of whom have been with him through 2003's Real Talk, and he placed only eight solo singles on the charts during this period. Nonetheless, this is a representative introduction to a singer who has unjustly remained in the margins. Most of the singles are featured here, along with several choice album cuts. Andy Kellman, Rovi
- Genre: R&B
- Subgenre: R&B/Soul, Hip-Hop/Urban
- Category Contemporary R&B, Urban
- Parental Advisory: Explicit Lyrics
- Artist: Dave Hollister
other Info.
- Online Item #: 11409799
- Store Item Number (DPCI): 244-02-2879
- Made in the USA or Imported


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37 year old man | Salt Lake City, UT, USA | Seeking women 21-35 within 50 miles
Is this really the place.....
*I'm taking a break from online dating so I am not currently a full member. All of these met ups began to feel like job interviews and the routine of running down interests, goals, etc. instead of just enjoying company got old. I will probably join again, but if you are interested pls send a message with contact info and we can take it from there ;) Originally from Montana, I moved to Utah 7 years ago (post college graduation) to pursue my professional career and be closer to friends. Though I love the town where I am from, I needed to get out and stand on my own two feet. Moving to Utah was an easy decision, but adjusting to the local culture proved more challenging. Over the last 7 years I have tried meeting new people, but due to the social dynamic here in Utah, I decided to give match.com a try as a way to meet new people with similar interests. I enjoy the outdoors, especially biking, skiing, and hiking. But I also appreciate a night out on the town. Discovering new places to eat and have a cocktail are among my favorite things to do. I am definitely a "work to live" person…I work hard, but I play hard, too. I like nice things, but they are not important to me. My main focus in life is to avoid the "keeping up with the Jones'" mentality and just enjoy quality time with the people close to me. Of course, I will continue to pursue my professional career in order to better my personal situation. But, my free time will be spent doing the things I enjoy and doing them with the important people in my life. As far as a companion, I'm hoping to find someone who is open to trying new things, who stands their ground, who is caring, and who is just fun to be around.
Camping , Coffee and conversation , Cooking , Dining out , Museums and art , Music and concerts , Exploring new areas , Nightclubs/Dancing , Performing arts , Watching sports
Basketball, Billiards / Pool, Other types of exercise, Skiing, Swimming, Walking / Hiking, Yoga
I exercise 3-4 times per week.
I like Birds, Cats, Dogs, Exotic Pets, Fish, Horses, Other
Some other viewpoint
Z{{Cta}} {{#if HasMoreInfo}} ?{{CtaSecondary}} {{/if}}
|What he is looking for
|6'0" (182cms)
|5'0" (152cms) to 6'11" (210cms)
|Body type:
|About average
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|Graduate degree
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I am not sure yet. Going to have to do more testing.
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text:
Neoseeker : Games : PC : Classic & Puzzle : Puzzle Games : Lego Alpha Team
BackgroundThe sinister Ogel has kidnapped 5 of the 6 Alpha Team members. As the only one still free, you must rescue your comrades and in doing add more characters you must use to master the 60+ puzzle levels that stand between the Alpha Team and Ogel. Use each member's unique skills to explore Ogel's compound.
Hardware Requirements
- Windows® 95/98/ME
- Pentium II 233 MHz (or faster) processor
- 4x speed (or faster) CD/DVD-drive
- 350 MB of free hard drive space
- 8 MB Direct3D Compatible Video Card (capable of 800x600 resolution in 16 bit color mode)
- DirectSound compatible soundcard
- Mouse and keyboard
Editor's Note:
Developed by Lego Media.
Added on: November 10, 2000
Official URLOfficial Site (NA)
Recent threads
endyouall played Lego Alpha Team
endyouall and 1 others own Lego Alpha Team
Jan 08, 01 8:42am
Great game for small (and large) kids
Nice variety of problems to solve. It's addictive in so much as half way through...
Dec 31, 00 12:11pm
Lots of fun
My 8 YO really likes this game. Graphics are really nice.
- Genre: Puzzle Games (PC)
- Developer: Digital Domain
- Publisher: Lego Media
Released North America October 2000 Europe Sep 22, 2000
Lego Series
- LEGO Legends of Chima: Laval's Journey
- LEGO City Undercover: The Chase Begins
- LEGO Harry Potter: Years 5-7
- LEGO Harry Potter: Years 5-7
- Lego Battles
- Lego Batman: The Videogame
- LEGO Star Wars II: The Original Trilogy


text:
"This was a very beautiful card that came out exactly how I imagined. The paper quality was very good and the printing was amazing. Our family and friends loved it!! Would highly recommend!!"
"I loved everything about this card except the size for some reason i thought it would be bigger ? Maybe it was the size i chose"
"I got my invitation yesterday. I'm so excited. They really exceeded my Expectations… Beautiful... The paper quality, the printing, everything is perfect. Customer service was excellent too, they keep me updated of the process and the designer answered my questions on time. The process was really fast, I got them days before the day they offered. So, I recommend TinyPrint 100%. Thanks a lot!"
"Absolutely love this Baptism invitation. It's simple, but elegant. It's the perfect color combination if you're not a fan of pink, but want just a touch."
"I get compliments about this card from everyone we invited to my son's christening! The paper quality is really thick and the colors are vivid. The only downside is I can't download pictures directly from my iPad, so I had to go through the extra process of downloading to Facebook so everyone already saw the really cute pic we chose."


text:
Great Britain: George II gold pattern 2 Guineas 1733,...
2013 January 6-7 Ancient & World Coin Signature Auction - New York #3021
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Waldorf Astoria
301 Park Avenue
New York, NY 10022
|Printable auction results for all items in the 2013 January 6-7 Ancient & World Coin Signature Auction - New York.
A Fabulous Early Georgian Pattern Double-GuineaGeorge II gold pattern 2 Guineas 1733, Young Laureate Head, S-3667, WR-69 (rated R5, 6-10 known), KM-Pn37, plain edge, obverse design by Croker, reverse design not attributed but probably by Tanner, PR63 NGC, a wonderfully choice specimen, amazing quality for a coin that is 280 years old, the image of the king superbly engraved and fully struck showing every minute detail, the reverse shield also fully impressed by the die, each side framed by deep, broad denticles at the rim, while the surfaces glitter with mirrored luster and are flawless other than for light hairlines, with perfect orange-peel texture to the gold, and blessed with gorgeous reddish gold toning. Truly, a coiner's masterpiece -- a major rarity from early in the Milled Coinage period, with stunning eye-appeal and historical importance. Majesty in gold!
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Mountains, Moose, and Miles: a Montanan's Alcan Highway Story
View Single Post
Ridin' in MT
Joined: Oct 2006
Location: Eastern Montana
Oddometer: 1,798
Sunday August 15, 2010 Day 10 Denali
Today is the turn around day. After messing around here in this beautiful north country Im turning around and starting the trek home. As I got in late last night I end up sleeping in a little, plus I need to get some laundry done. A quick stop at a car wash ends up in a chance meeting with another F800GS rider. He has a 2010 model and found some neat tires that I hope to try. Its 11:15 am and Im finally packed up and heading south from Fairbanks toward Denali.
Leaving the forest fire smoke around Fairbanks it is a clear day and Im enjoying the sunshine. The road has some nice views of the forested valleys.
As I get closer to the park, the mountains are getting larger and more rugged. I stopped for gas and see a rider on a CBR with full gear. Talking with the air force serviceman, I find out he has just come from Denali Park, and there were clouds all around but Denali was in full view.
This is the end of the line for the private vehicles. Looking at this bridge I have this funny picture in my head of Gandalf in forest service uniform standing at the end saying You Shall Not Pass. Chuckling to myself I take a few pictures.
An outhouse with a sod roof is a little unique, and the rocky valley behind it is striking.
Down by the river, a caribou is grazing. Its getting later in the day and I need to keep moving. Fly you fools echoes in my mind as I load up and head back out of the park.
It appears that the clouds have moved in and Mount McKinley is hiding again. Like many tourists, I get to point to the clouds and say, it would be right there behind that tree. For those not aware of geography Mount McKinley, or Denali in the native dialect, is the tallest peak in North America at 20,320 feet.
The mountains around the park are still striking and I stop for one more picture before leaving the park.
Out on the highway the aspen are starting to change color out on the mountain sides.
Im taking the highway south to the junction of the Denali Hwy. I stop at this little café along the road. This was a very nice little find as the food was excellent.
They had an amazing halibut steak with rice and fresh beans, and I had the blueberry crisp and ice cream for dessert.
The Denali Highway is a gravel road that goes from Cantwell to Paxton. It provides access to the valley and rivers that drain off of the glaciers on the flanks of Mt Hayes. Im not sure I would designate this road as a highway, but it is going to provide a nice trip for me.
The clouds are moving in behind me, but these mountains are green and stand above the boreal forests in the valley the road winds through.
The road breaks out of the mountains and winds around the ridge on the south side of the valley. To the north Mt Hayes stands out and the sun lights up the slopes while the valley is shadowed by the grey clouds. It was a pretty striking effect.
Hunters were out in force looking for critters. Campers and tents were parked along the approaches and turnouts beside the road.
The road is just a three track and the hunters and myself are travelling along at a fair clip. As I near Paxon it is getting darker, and the clouds are moving in. There is enough light to take one more picture.
I hit the Henderson Highway at Paxon and head north a little ways to find a campsite.
Stats for Day 10: 328 miles, 6.8 gallons of fuel, 8.75 hours
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