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The human being is finite in all perfections.
This means that if he is nice, his niceness has a limit; if he is patient, his patience has a limit; if he is forgiving his forgiving has a limit; if he is good, his goodness has a limit. A common stupid mistake we make is to keep taking someone for granted until we place the straw that breaks the camel's back. We should always remember that human beings are finite in all perfections. On the other hand, theologians tell us that God is infinite in all perfections, and we may experience that personally.
On the topic of tiredness, we consider the ordinary human being with a finite human nature living in a world of good and evil, either of which can easily overwhelm the ordinary man's limitations. There is a point that a human being reaches that he or she ends up lying, or cheating, or stealing, or hating, or destroying, or killing, or committing suicide. Nazi-type experimenters on human beings know this all too well. We do not need such evil investigations to understand nature. Common sense and experience of ordinary life suffice to guard our own life and our relationships with other human beings.
Tiredness can come from experiences that are too great or experiences that are too chronic. A student studying to face exams can get tired of studying but the fact that there is an exam date keeps him or her going against the tiredness until the exam date. He or she knows that an opportunity to rest and unwind is at hand. In aspects of life where a definite hurdle in sight can be passed, the possibility of an end restrains one's psyche from "losing it". On the other hand, there are experiences that one may be tired of and there is no light at the end of the tunnel. These are the situations that very often break down human beings, destroy human nature, change people's personalities, or cause humans to turn to evil solutions.
The uncertainty of an end to tiredness turns one to look for distractions from the situation which may be as bad as indulgence in drugs, drink, sex, or extremisms. In unbearable situations, an escape is sought and this can be in irreversible evils such as sabotage, vandalism, murder, or suicide. Overwhelming tiredness can result in the sufferer sinking into definite vice such as envy, anger, hatred, or resentment; or the person out rightly losing it - going depressed, melancholic, rebellious, vicious, malicious, or insane. In present day America, every now and then, somebody takes a gun and goes on a shooting spree. In present day Nigeria, many people at all levels of society gulp public or private funds.
We can get tired of all sorts of experiences and situations: a relationship, loneliness, an environment, a job, joblessness, poverty, difficulties, suffering, pain, lack, interferences, monotony, stereotypes, a family problem, oppression, persecution, victimization, unmet needs and desires, enmities, rivalries, exploitation, as well as religious, social, economic, or political problems. Many of us live with chronic moans and groans.
Tiredness can be physical, emotional, psychological, mental, or spiritual. Physical tiredness is perhaps the easiest to bear and to recover from and usually we know how to recover from such through nourishment, rest, and sleep. Emotional, mental, and spiritual tiredness are not always easy to recognize, to accept, to deal with, or to recover from. Because of this, they are a source of many evils, sudden catastrophes, and irreparable damages in personal lives, in families, and in social life.
Different persons have their own thresholds (or safe limits) for tiredness, whether physical, mental, emotional, or spiritual tiredness. Immaturity is characterized by a low threshold for all these. Commonly, the more mature or the more trained we are within our physical, mental or spiritual capacities, the higher our thresholds and the further we can go without getting tired. For example, an athlete could take the physical strains that most humans cannot undergo. An academic can read technical papers all day long whereas most people would abandon them in in half an hour. A nun might have no need for human love, or children, or personal properties because she is conditioned to live a celibate life whereas most humans would suffer emotionally without these. Sometimes we hear such comments as: "I don't know how she puts up with that man; if I were in her shoes, I would have killed him!" Spouses have sometimes done away with their other half because they got "tired" of some suffering and of having to forgive.
Tiredness of some sort is inevitable along the courses of our lives. It often leads to negative situations such as crises but may be channelled to positive situations such as transitions. Commonly, we seek to escape: a prisoner runs away from prison, a family breaks up, a nation goes into revolution. The plethora of factors that make us tired are very different from one individual to another but the experience of tiredness is still the same thing. We will therefore consider coping with and dealing with physical, mental, emotional, psychological, and spiritual tiredness.
Dr. 'Bola John is a biomedical scientist based in Nigeria and in the USA. For any comments or questions on this column, please Email [email protected] or call 07028338910
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What Boko Haram and NADECO have in common
As we watched troubled President Goodluck Ebele Jonathan in his black kaftan with black cap behind the distraught emir of Kano last week, it was ... Full story


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"If a man with no arms and a man with no legs started learning karate, the same light bulb would appear over every head in Japan. Thats right: Glue them together and see if it can kill a panda."
Honourable Mention (because it was SF not UFC): Daniel Cormier.
Favourite Fighters: A. Silva, Velasquez, Swanson, Bisping, W. Silva, Barnett, Faber, Dos Santos, Manuwa, McCall, Pickett & Poirier
Least-Favourite Fighters: Story, Sylvia, Browne & Lentz
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Neon Hitch Hits The Road With 3OH!3 10/23
British singer and songwriter Neon Hitch will join her pals in 3OH!3 for a series of dates on the electro hip-hop group's current "Streets of Gold" Tour beginning October 23rd. Hitch first worked with the group on "Follow Me Down," which was included on Almost Alice - a companion soundtrack to the Tim Burton film adaptation of Alice in Wonderland.
Signed to Warner Bros. Records by Senior Vice President of A&R Kara DioGuardi, Hitch is currently hard at work on her debut album with executive producer Benny Blanco (Ke$ha, Spank Rock, 3OH!3, Britney Spears). The album is shaping up to be a collection of striking songs that deploy Hitch's soulful, jazz-inflected vocals atop an organic backdrop of eclectic pop melodies and hip-hop tinged beats.
Hitch already has several high-profile songwriting credits to her name. She co-wrote "Blah Blah Blah" on Ke$ha's No. 1 album Animal, "Traces," which will appear on Sky Ferreira's upcoming debut album, as well as "Stupid Love Letter," which is included on the Friday Nights Boys' album Off The Deep End and the When In Rome soundtrack. Hitch has worked with Miike Snow (appearing on Blanco's remix of "Burial"), Greg Kurstin, Sia, Mike Posner, Deadmau5, DJ Chuckie, Toby Gad, and Cathy Dennis.
Check out Neon Hitch on the road with 3OH!3:
10/23 Providence, RI Lupo'd At the Stand
10/24 Montreal, QC Metropolis
10/26 Allentown, PA Crocodile Rock
10/27 Columbus, OH LC Pavilion
10/30 Pittsburgh, PA Ches-A-rena
10/31 Covington, KY Madison Theatre
11/01 Indianapolis, IN Egyptian Room @ Murat Centre
About Author
- Casting Roundup: Sarah Chalke, Kim Raver Headline New Pilots
- ADVENTURE TIME Headed to the Big Screen?
- Pilot Season Roundup: Colm Feore, Daniel Stern, Dave Annable to Star in New Shows
- James Franco to Star in New Fox Comedy, WHY HIM?
- Christopher Meloni to Star in WGN America's Slave Drama UNDERGROUND
- Check Out Alex Dunphy's Full College Essay from Latest MODERN FAMILY Episode
- Photo Flash: HBO Reveals Key Art for GAME OF THRONES Season 5
- Syfy to Honor Leonard Nimoy with Special Programming This Sunday
- Grammy Winner Kelly Clarkson Exclusively Premieres New Music from New Album on MTV, VH1 & CMT First
- CONSTELLATIONS' Jake Gyllenhaal and Ruth Wilson Set for THEATER TALK This Weekend


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Senators Announce GM Bryan Murray Has Cancer
The Ottawa Senators announced today that General Manager and President of Hockey Operations Bryan Murray has been recently diagnosed with cancer. The Sens organization issued the following statement: "Mr. Murray is undergoing further testing and will begin treatment immediately
Senators Send Jason Spezza To Dallas
ESPN's Pierre LeBrun reports that although the deal isn't final yet, the Ottawa Senators have agreed to
Jason Spezza Doesn't Want To Play In Canada
Though the Calgary Flames were set to bid on Jason Spezza, he apparently doesn't want to play there or anywhere else in the country.
Maclean Calls Out Karlsson
Paul Maclean's Ottawa Senators didn't do well this year. They missed the playoffs for the first time in three years. However, Maclean feels that how the Senators go depends on how well Erik Karlsson plays. Karlsson is still recovering
NHL: Ryan Considering Staying In Ottawa
Maybe the deal for Bobby Ryan wasn't so pointless after all. Ryan has now said that he is considering signing with Ottawa long term. He was acquired in the offseason from the Anaheim Ducks who weren't going to resign
NHL: Senators' Maclean Numb After Loss
The Ottawa Senators season can't end soon enough. Their uninspiring season has taken a sharp turn as their play has made their coach "numb." Paul Maclean, in his press conference, has no answers for his teams play except to
NHL: Sens GM Not Commenting On Maclean's Future
Bryan Murray of the Ottawa Senators is not commenting on whether or not the coach who has gotten his team to the playoffs twice in the past two years, Paul Maclean, is going to be staying with the team
VIDEO: Blackhawks Shaw Ejected For Spearing
The Chicago Blackhawks are in a bit of a free fall of late and their frustration is starting to show on the ice. Andrew Shaw was ejected Friday night for spearing Ottawa Senators Zach Smith. Here's the video: For
Bobby Ryan To Miss Rest Of Season
Bobby Ryan's first campaign with the Ottawa Senators has been something of a disappointment, but
Lightning Win Fifth In A Row, Defeat Senators 5-4
Teddy Purell Notches Pair Of Goals To Lead Bolts To Victory


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Great Condo-Priced Right, Last Minute Bookings
Egg Harbor Condo
1 Bedroom / 1 Bathroom / Sleeps 4Condo / 1 Bedroom / Sleeps 4
/ nightEmail Owner
|Per night:
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Our rates are 25% off Landmark Resort rates. The Landmark is the largest condo development in beautiful Door County overlooking Green Bay in Egg Harbor. This newly updated 1 Bedroom woodview, ground floor suite is located in the Flagship Building of the Landmark Resort. The Bedroom...
Outstanding all the way around
August 19, 2014
The title says it all. The booking for this unit was flawless and was as easy as reserving a room at any hotel. Upon arrival the staff was super friendly and courteous, and took care of us right away. The facilities at the Landmark, from the room we stayed in to the grounds, are immaculate. This unit was spotless, and everywhere we went in the resort held up that same standard. The pools are immaculate, the restrooms are spotless, the whirlpool facilities clean, the decks have great outdoor furniture. I can't say enough how impressed I was with the room we rented and all the amenities. i did not use the shuffleboard, basketball or tennis courts but I could see they were in great condition. The Carrington restaurant was outstanding and took care of our request to ensure service in time for a play we went to see. And the food was terrific. I generally like to stay in Door in units with a water view. This unit has a wood-view but the water view is literally just a few steps from the door. And the views, including sunsets, are spectacular. The ultimate recommendation is if you would recommend this unit to someone else - the answer is absolutely.
Steven Savaglio, Aurora, IL


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Join us for 66th Frankfurt Book Fair from 14 to 18 October 2015!
To secure your Trade Visitor Ticket or your Trade Visitor Ticket BUSINESS for this year's Book Fair, select the link below to get to the trade ticket overview and ticket shop.
To the ticket overview and shop
Discover a Fair full of opportunities:
Starting in 2015, the Frankfurt Book Fair will be even more structured according to individual themes and market segments. The new Fair is: more vibrant, more dynamic and more international!
Discover the new Book Fair


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YIELD: Makes 5 small loaves
Into a bowl sift together the flour, the baking powder, the baking soda, and the salt. In a large bowl with an electric mixer cream the butter with the honey and beat in the vanilla, the eggs, 1 at a time, and the buttermilk. Add the flour mixture, beat the batter until it is just combined, and stir in the dates and the pecans. Divide the batter among 5 buttered and floured loaf pans, each 5 3/4 by 3 1/4 by 2 inches, and bake the breads in the middle of a preheated 350°F. oven for 40 to 45 minutes, or until a tester comes out clean. Remove the breads from the pans and let them cool, right sides up, on a rack. The breads keep, wrapped well in plastic wrap and foil, chilled for 1 week or frozen for 1 month.


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sermonsearch's UploadsBack to sermonsearch's channel.
- RewindBuy Now: http://www.sermonsearch.com/videoillustrationdetail.aspx?id=67659
Beneath the surface, we sometimes forget about God's faithful promises to us.sermonsearch2011-01-10T13:53:2016,007 views00:01:41
- Keep Love AliveBuy Now: http://www.sermonsearch.com/videoillustrationdetail.aspx?id=66709 When couples are young it's easy for love to be their #1 priority. As life gets complicated...sermonsearch2011-01-05T18:11:5116,918 views00:02:42
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- When We PrayBuy Now: http://www.sermonsearch.com/videoillustrationdetail.aspx?id=59896 What are we really asking for when we pray for patience, forgiveness, or understanding? Ult...sermonsearch2011-01-03T14:25:4345,931 views00:01:16
- WHY WE CELEBRATE NEW YEARSThe celebration of the end of one year and the beginning of another is the perfect time to focus on the very real need all Christians have to leave the past behind and press on to the future. Buy Now: sermonsearch2010-12-30T13:01:24117,743 views00:02:36
- WorryBuy Now: http://www.sermonsearch.com/videoillustrationdetail.aspx?id=60060 What do you worry about? Your job, your family, losing your home, money, illness? This ...sermonsearch2010-12-22T16:38:2825,814 views00:02:02
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We work so hard to make Christmas happen and it's over in an instant. By the next morning...sermonsearch2010-12-20T16:00:4514,436 views00:01:37
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NHL Rangers' Sather Drops GM Title Steelers Move Toward Super Bowl Bid Arizona State Transitions To Adidas New Balance Launches Global Campaign Arum's Top Rank Sues Haymon, PBC Chevy The Latest Daytona Rising Founding Partner SNY, Citi Present Special Mets Telecast Classified Advertisements Nike's Phil Knight Stepping Down In '16 USOC Praises Boston 2024's Progress
SBD/Issue 82/FinancePrint All
CART Shares Fall 13.9% To Hit 52-Week Low Amid News With ISL
Shares of CART fell 13.9% yesterday after A.G. Edwards "questioned the relationship" between CART and ISL Marketing, according to a report in REUTERS, which notes A.G. Edwards downgraded CART stock to "maintain" on Tuesday "due to uncertainty in regards to our ISL sponsorship guarantee." CART has a nine-year deal with ISL. The stock closed at $16.25, a new 52-week low. The previous low was $18.13. CART CEO Joseph Heitzler said: "Although we are in discussions with ISL, it is premature to comment on the outcome of these discussions or the effect of ISL's management changes and other sports property renegotiations on CART's revenues and marketing plans" (REUTERS, 1/17).
Ignite Sports Receives $17M In Third Round Of Financing
Chicago-based Ignite Sports Media has secured $17M in third-round financing, according to Terry Lefton of TheStandard.com, who wrote the financing is "a development that belies the squeeze on content sites generally, and on second-tier sports sites in particular." New investors "include the AIG Global Sports and Entertainment Fund, whose partners include the Interpublic Group and General Motors." Williams Communications and Comdisco Ventures are also new investors. Ignite CEO Hank Adams said that "the new capital will be used to further Ignite's interactive TV efforts, including a current project dealing with the development of content for a cable TV company that will then package the content for sale to next-generation set-top boxes." Adams added that 50% of Ignite is "now owned by outside investors." Lefton noted that Ignite raised $5M in its prior two financing rounds, and that Ignite plans to use the new funds to "staff up its sales force." As part of the new financing, Octagon Group, the sports marketing division of Interpublic, will "help market Ignite's interactive expertise" (TheStandard.com, 1/17).


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Are you Ming-Hsun Wu?Claim your profile
Publications (30)67.95 Total impact
Article: VEGF-D and A Preoperative Serum Levels Predict Nodal and Distant Metastases in Differentiated Thyroid Cancer Patients[Show abstract] [Hide abstract]
ABSTRACT: Preoperative tumor aggressiveness biomarkers may help surgeons decide the extent of an operation. However, whether serum angiogenetic factors can be used to predict the prognosis of patients with differentiated thyroid cancer is still unclear. Seventy-six DTC patients were prospectively recruited. Preoperative serum samples were collected and measured for Tie-2, Ang-1, Ang-2, VEGF-A, and VEGF-D levels. The potential correlations between their serum levels and clinicopathologic features as well as their prognoses were analyzed. Older age (>45 years old) and higher VEGF-A serum levels were independent predictors of extrathyroidal extension. The VEGF-D serum level was an independent factor for lymph node metastases and VEGF-A was an independent factor for distant metastases. None of these serum angiogenetic factors were significantly different between patients who were disease free and those with recurrences. The presence of lymph node metastases was the only independent factor for recurrence over the 2-year follow-up. Preoperative serum VEGF-A and VEGF-D levels were significantly elevated in DTC patients with distant and lymph node metastases. These findings, when combined with other clinicopathological factors, may help in surgical decisions.World Journal of Surgery 02/2015; 39(7). DOI:10.1007/s00268-015-3016-6 · 2.35 Impact Factor
Article: Prospective double-blind randomized study on the efficacy and safety of an n-3 fatty acid enriched intravenous fat emulsion in postsurgical gastric and colorectal cancer patients[Show abstract] [Hide abstract]
ABSTRACT: A lipid emulsion composed of soybean oil (long-chain triglycerides, LCT), medium-chain triglycerides (MCT) and n-3 poly-unsaturated fatty acids (PUFAs) was evaluated for immune-modulation efficacy, safety, and tolerance in patients undergoing major surgery for gastric and colorectal cancer. In a prospective, randomized, double-blind study, 99 patients with gastric and colorectal cancer receiving elective surgery were recruited and randomly assigned to either the study group, receiving the n-3 PUFAs enriched intravenous fat emulsion (IVFE), or the control group, receiving a lipid emulsion comprised of soybean oil and MCTs (0.8 - 1.5 g . kg-1 . day-1) as part of total parenteral nutrition (TPN) regimen from surgery (day -1) up to post-operative day 7. Safety and efficacy parameters were assessed on day -1 and post-operative visits on day 1, 3, and 7. Adverse events were documented daily and compared between the groups. Pro-inflammatory markers, laboratory parameters, and adverse events did not differ prominently between the 2 groups, with the exception of net changes (day 7 minus day -1) of free fatty acids (FFAs), triglyceride, and high-density lipoprotein (HDL). Net decrease of FFAs was remarkably higher in the study group, while the net increase of triglyceride and decrease of HDL was significantly lower. The n-3 PUFA-enriched IVFE showed improvements in lipid metabolism. In respect of efficacy, safety and tolerance both IVFE were comparable. In patients with severe stress, there is an inflammation-attenuating effect of n-3 PUFAs. Further, adequately powered clinical trials will be necessary to address this question in postsurgical GI cancer patients.Trial registration: US ClinicalTrials.gov NCT00798447.Nutrition Journal 01/2015; 14(1):9. DOI:10.1186/1475-2891-14-9 · 2.64 Impact Factor
- The American Journal of the Medical Sciences 01/2015; 349(4). DOI:10.1097/MAJ.0000000000000404 · 1.52 Impact Factor
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ABSTRACT: To test whether computerized quantification of ultrasonic heterogeneity can be of help in the diagnosis of thyroid malignancy, we evaluated ultrasonic heterogeneity with an objective and quantitative computerized method in a prospective setting. A total of 400 nodules including 271 benign thyroid nodules and 129 malignant thyroid nodules were evaluated. Patient clinical data were collected, and the grading of heterogeneity on conventional gray-scale ultrasound images was retrospectively reviewed by a thyroid specialist. Quantification of ultrasonic heterogeneity (heterogeneity index, HI) was performed by a proprietary program implemented with methods proposed in this article. HI values differed significantly between benign and malignant nodules, diagnosed by a combination of fine-needle aspiration and surgical pathology results (p < 0.001, area under the curve = 0.714). The ultrasonic heterogeneity of these samples, as assessed by an experienced clinician, could not significantly differentiate between benign and malignant thyroid nodules. However, nodules with marked ultrasonic heterogeneity had higher HI values than nodules with homogeneous nodules. These results indicate that the new computer-aided diagnosis method for evaluation of the ultrasonic heterogeneity of thyroid nodules is an objective and quantitative method that is correlated with conventional ultrasonic heterogeneity assessment, but can better aid in the diagnosis of thyroid malignancy.Ultrasound in Medicine & Biology 09/2014; 40(11). DOI:10.1016/j.ultrasmedbio.2014.06.009 · 2.10 Impact Factor
Article: Glutamine Supplementation Attenuates Expressions of Adhesion Molecules and Chemokine Receptors on T Cells in a Murine Model of Acute Colitis[Show abstract] [Hide abstract]
ABSTRACT: Background. Migration of T cells into the colon plays a major role in the pathogenesis in inflammatory bowel disease. This study investigated the effects of glutamine (Gln) supplementation on chemokine receptors and adhesion molecules expressed by T cells in mice with dextran sulfate sodium- (DSS-) induced colitis. Methods. C57BL/6 mice were fed either a standard diet or a Gln diet replacing 25% of the total nitrogen. After being fed the diets for 5 days, half of the mice from both groups were given 1.5% DSS in drinking water to induce colitis. Mice were killed after 5 days of DSS exposure. Results. DSS colitis resulted in higher expression levels of P-selectin glycoprotein ligand- (PSGL-) 1, leukocyte function-associated antigen- (LFA-) 1, and C-C chemokine receptor type 9 (CCR9) by T helper (Th) and cytotoxic T (Tc) cells, and mRNA levels of endothelial adhesion molecules in colons were upregulated. Gln supplementation decreased expressions of PSGL-1, LFA-1, and CCR9 by Th cells. Colonic gene expressions of endothelial adhesion molecules were also lower in Gln-colitis mice. Histological finding showed that colon infiltrating Th cells were less in the DSS group with Gln administration. Conclusions. Gln supplementation may ameliorate the inflammation of colitis possibly via suppression of T cell migration.Mediators of Inflammation 05/2014; 2014:837107. DOI:10.1155/2014/837107 · 2.42 Impact Factor
Article: Randomized Clinical Trial of New Intravenous Lipid (SMOFlipid(R) 20%) Versus MCT/LCT in Adult Patients Undergoing Gastrointestinal Surgery.[Show abstract] [Hide abstract]
ABSTRACT: Background: SMOFlipid® 20% is intravenous lipid emulsion (ILE) containing long-chain triglycerides (LCT), medium-chain triglycerides (MCT), olive oil, and fish oil as a mixed emulsion containing α-tocopherol. The aim was to assess the efficacy of this new ILE in gastrointestinal surgery compared with MCT/LCT. Methods: In this prospective study, 40 patients were randomized to SMOFlipid® 20% or MCT/LCT (Lipovenoes® 20%) group. Clinical and biochemistry data were collected. Inflammatory markers (CRP, IL-6, IL-10, TNF-α, TGF-β1) and oxidative stress (ROS and superoxide) were measured. Results: Thirty-five patients (17 males and 18 females) with a mean age of 57 years completed the study. The patients' demographic characteristics (age, gender, height, body weight, and BMI) were similar without significant differences between groups. The increment of triglyceride on day 6 from baseline was significantly lower in SMOFlipid® group than in Lipovenoes® MCT/LCT group. Inflammatory markers, as well as superoxide radical and total oxygen radical were not different between groups. Conclusions: Despite the comparable effect on inflammatory response, because of its well-balanced fatty acid pattern, relatively low n-6:n-3 ratio, and high vitamin E content, SMOFlipid® had a better triglyceride-lowering effect as compared with MCT/LCT in adult patients undergoing gastrointestinal surgery.Journal of Parenteral and Enteral Nutrition 11/2013; 38(7). DOI:10.1177/0148607113512869 · 3.14 Impact Factor
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ABSTRACT: To clarify and determine whether power Doppler sonograms are useful for the detection of malignant thyroid nodules, a computerized quantification method was used to evaluate the vascular density of a thyroid nodule in a prospective setting. Sonographic power Doppler images were collected in consecutive frames (45 frames of images), and a proprietary program (AmCAD-UV) was implemented using methods proposed in this article automatically calculated a quantified power Doppler vascular index (PDVI). The minimum PDVI value (PDVImin) was suggested as a measure of the vascular density of the nodule. The vascular densities of the peripheral and central areas of the nodule, referred to as central PDVImin and Ring PDVImin, respectively, were also evaluated. For 238 tumors (79 malignant and 159 benign) from 208 patients, all of the proposed indices of benign lesions were significantly higher than those of the malignant lesions. The area under the receiver operating characteristic curve (AUC) reaches 71% with the PDVImin. When the vascular patterns were further classified into intra-nodular and peripheral vascularity types, no vascularity type was observed significantly more frequently in malignant nodules than in benign nodules. These proposed computerized vascular indices provide a quantification method to objectively evaluate thyroid nodules and have potential as predictors of thyroid malignancy. The conventional vascular characterizations of malign nodules, that is, more vessels are observed in malignant nodules than in benign nodules, are shown to be unreliable in our study. Instead, a higher value of the quantified power Doppler vascular density was observed in benign nodules.Ultrasound in medicine & biology 06/2013; 39(9). DOI:10.1016/j.ultrasmedbio.2013.03.009 · 2.10 Impact Factor
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ABSTRACT: Background/Aims: It has been a matter of debate whether the advantage of gasless laparoscope setting is obvious when compared with the conventional operation. Thus, we compare the systemic response of proinflammatory markers and the adhesion molecules in serum levels after surgery between these two procedures. Methodology: There were 23 patients in the gasless laparoscopy (GL) group, and 12 patients in the open surgery (OS) group. Results: The created wound length was smaller in the GL group (5.3±0.3cm vs. 8.9±0.5cm), the post operative recovery including the visual analog pain score on op day and day 1, flatus day, and hospital stay were also shown less in GL group. The levels of IL-6, IL-8 and ICAM were significantly lower in the GL group. Conclusions: Immune response is less in gasless laparoscopy-assisted gastrectomy (GLAG) when compared with traditional approach, and the difference may have effects on the post operative recovery.Hepato-gastroenterology 11/2012; 60(125). DOI:10.5754/hge12944 · 0.91 Impact Factor
Article: Parenteral Glutamine Supplement has Synergic Effects in Minimally Invasive Surgery a Subtotal Gastrectomy Patients[Show abstract] [Hide abstract]
ABSTRACT: Background/Aims: Exogenous glutamine supplement is known to improve morbidity and mortality of critically-ill patients. This study was conducted to elucidate the role of glutamine in minimally invasive surgery. Methodology: We retrospectively reviewed subtotal gastrectomy patients in National Taiwan University Hospital from Dec 2005 to Dec 2008. The patients were divided into three groups. Group 1 underwent subtotal gastrectomy by laparotomy without glutamine supplement, group 2 underwent subtotal gastrectomy by laparotomy with glutamine supplement and group 3 underwent gasless laparoscopy-assisted subtotal gastrectomy with parenteral glutamine supplement. Results: There were 155 patients in total; 85 patients in group 1, 17 in group 2 and 53 in group 3. The mean flatus days after operation are 3.6, 3.1 and 2.8 for groups 1, 2 and 3, respectively (p=0.001). Oral intake after operation was commenced after 6.7, 5.0 and 4.7 days (p=0.006). The body temperature had borderline differences between groups 3 and 1. There were significant differences in postoperative systemic responses including heart rates (p<0.001) and tenderness (p=0.011) 5 days after operation for group 3 vs. group 1. Minimally invasive surgery was a negative factor for postoperative body temperature change. Glutamine was a significant factor for postoperative heart rate change and reduction of tenderness. Conclusions: Glutamine supplement may have synergic effects of rapid recovery in minimal invasive surgery for subtotal gastrectomy patients by minimizing the postoperative systemic response and accelerating recovery.Hepato-gastroenterology 09/2012; 59(118):1776-9. DOI:10.5754/hge10270 · 0.91 Impact Factor
Article: Eicosapentaenoic acid and docosahexaenoic acid inhibit macrophage-induced gastric cancer cell migration by attenuating the expression of matrix metalloproteinase 10[Show abstract] [Hide abstract]
ABSTRACT: Uptake of docosahexaenoic acid (DHA)/eicosapentaenoic acid (EPA) improves the treatment of cancer and reduces tumor-associated macrophage count. However, the mechanism of this relationship is still unclear. In this study, macrophages enhanced gastric cancer cell migration ability and induced the differentially expressed matrix metalloproteinase genes (MMP1, MMP3 and MMP10) of N87 as identified by polymerase chain reaction array. Furthermore, DHA and EPA inhibited macrophage-enhanced cancer cell migration and attenuated MMP10 at both the RNA and protein level. The suppression of MMP10 expression was further verified by zymography and antibody blocking experiments. Additionally, DHA and EPA attenuated expression of macrophage-activated extracellular-signal-regulated kinase (ERK) and signal transducers and activators of transcription 3 (STAT3) in cancer cells. Attenuation was verified by demonstrating blockade with specific inhibitors and thereby increased MMP10 expression. Accordingly, we hypothesized that macrophage enhances cancer cell migration through ERK and STAT3 phosphorylation and subsequent increased MMP10 expression and that DHA and EPA could attenuate these signals. These findings not only explain the beneficial effects of DHA/EPA, but also point to ERK/STAT3/MMP10 as the potential targets for gastric cancer treatment.The Journal of nutritional biochemistry 01/2012; 23(11):1434-9. DOI:10.1016/j.jnutbio.2011.09.004 · 4.59 Impact Factor
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ABSTRACT: To improve the ultrasonographic detection rates of thyroid cancers with microcalcifications, we propose to enhance the sensitivity of sonographic calcifications detection and to avoid interobserver variation by a computerized quantification method in a prospective setting. A total of 227 participants with 258 nodules were evaluated. Among them, two nodules were excluded for suspicious aspiration cytology results without pathologic proof. Among the remaining 256 nodules, the diagnosis of 181 nodules was verified by surgical pathology and the diagnosis of 75 was based on fine needle aspiration (FNA) biopsy results. There were 173 benign thyroid nodules and 83 malignant thyroid nodules, which included 74 papillary carcinomas. Patient clinical data were collected and the presence of calcifications on conventional gray-scale ultrasound images was retrospectively reviewed by a thyroid specialist. Quantification of cystic components and calcifications was automatically performed by a proprietary program (AmCAD-UT) implemented with methods proposed in this article. The calcification index (CI) was calculated after the cystic component was excluded. The CI between benign and malignant nodules diagnosed by combined FNA biopsy and surgical pathology results (total number, 256) showed a significant difference (p < 0.0001, AUC = 0.746). Furthermore, we excluded patients without surgical pathology results for further validation and the CI between benign and malignant nodules confirmed by pathology results (total number, 181) showed a significant difference (p < 0.0001, AUC = 0.763). To learn whether our computer program increased our diagnostic capabilities, we analyzed human investigators and their abilities to detect and evaluate. In this study, calcifications were noted in 48.19% (40 of 83) of malignant thyroid nodules and in 10.98% (19 of 173) of benign nodules. This new computer-aided diagnosis method to evaluate the sonographic calcifications of thyroid nodules is a more sensitive and more objective method. It can provide better sensitivity than conventional methods in the diagnosis of thyroid malignancies containing microcalcifications.Ultrasound in medicine & biology 06/2011; 37(6):870-8. DOI:10.1016/j.ultrasmedbio.2011.03.002 · 2.10 Impact Factor
Article: Serum vascular endothelial growth factor-D levels correlate with cervical lymph node metastases in papillary thyroid carcinoma.[Show abstract] [Hide abstract]
ABSTRACT: The aim of this multicenter study was to evaluate the clinical relevance of serum vascular endothelial growth factor-D (VEGF-D) in papillary thyroid carcinoma (PTC). This prospective study consisted of 74 patients with primary PTC and 15 patients with benign thyroid nodules treated from 2008 to 2009. VEGF-D concentration was compared with patient clinicopathologic features and lymph node metastases. There was no significant difference in mean serum VEGF-D levels between the PTC and benign thyroid nodule groups. Within the PTC group, serum VEGF-D levels were significantly higher in patients with lymph node metastases than in patients without metastases (241.92 vs. 213.89 pg/ml, respectively; P = 0.035). Receiver operating characteristic curve analysis revealed that preoperative serum VEGF-D levels were predictive of lymph node metastases in the patients >45 years. Serum VEGF-D level that was correlated with the presence of cervical lymph node metastases in PTC patients might be a useful prognostic indicator.Growth factors (Chur, Switzerland) 02/2011; 29(2-3):57-62. DOI:10.3109/08977194.2011.557373 · 3.09 Impact Factor
Article: Gasless Laparoscopy-Assisted Surgery for Intraabdominal/Retroperitoneal Tumor of Unknown Origin: A Bridge Between Total Laparoscopic Surgery and Conventional Open Surgery[Show abstract] [Hide abstract]
ABSTRACT: Gasless laparoscopy-assisted surgery has been utilized in many abdominal diseases, and it has been proved to be effective and efficient compared with conventional open surgery. The study was conducted to evaluate the efficacy of gasless laparoscopy-assisted surgery in management of intraabdominal/retroperitoneal tumor of unknown origin. From June 2004 to April 2009, nine patients who underwent gasless laparoscopy-assisted surgery for intraabdominal/retroperitoneal tumor of unknown origin were recruited. Intraabdominal/retroperitoneal tumor of unknown origin was defined as (1) diagnosis of enlarged retroperitoneal lymph node; (2) evaluation of peritoneal or mesenteric lesion, or tumor of nondigestive systems; and (3) staging of intraabdominal malignancy. Four patients underwent gasless laparoscopy-assisted surgery for retroperitoneal enlarged lymph nodes, four for evaluation of intraabdominal lesion, and two for staging of the malignancy. Sufficient tissue was obtained from all patients, and the diagnosis was as follows: three lymphomas, three peritoneal carcinomatoses, two chronic imflammations, and one benign tumor. Three purposes can be achieved: a familiar method for the surgeon compared with total laparoscopic surgery, easy accessibility for further oncological management, and intraoperative miniconversion for peritoneal examination. It is a safe and effective way to obtain tissue for pathology and feasible in case of necessary sequential tumor resection.Journal of Laparoendoscopic & Advanced Surgical Techniques 10/2010; 20(10):825-30. DOI:10.1089/lap.2010.0263 · 1.19 Impact Factor
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ABSTRACT: We had developed an innovative method of minimally invasive surgery using gasless laparoscopy in resection of the small bowel lesion. This study aimed at evaluating the feasibility and efficacy of this procedure by comparison with traditional open small bowel surgery. A wedge or segmental resection of the small bowel for removal of the lesion was performed in 25 patients at National Taiwan University Hospital from September 2006 to January 2009. Thirteen patients underwent gasless laparoscopy-assisted surgery (GLAS), and 12 patients underwent open surgery. The perioperative characteristics and clinical results between the two groups were compared. The demographics, clinical data, lesion size, and operative time were comparable between the GLAS and open surgery groups, but the wound length and blood loss were significantly less in the GLAS group (P < 0.001 and P = 0.021, respectively). The time to first postoperative flatus and first oral intake were significantly less in the GLAS group (P = 0.007 and 0.036, respectively). No major complication occurred in either group. No tumor recurrence was found after a median follow-up period of 14 months (range = 1-30) in the GLAS group. GLAS for resection of the small bowel may be a feasible and safe procedure for the small bowel lesions. It has the advantages of better cosmetic outcome, less blood loss, and earlier recovery of bowel movement.Journal of Laparoendoscopic & Advanced Surgical Techniques 10/2010; 20(8):699-703. DOI:10.1089/lap.2009.0417 · 1.19 Impact Factor
Article: Gasless Laparoscopy-Assisted Versus Open Resection for Gastrointestinal Stromal Tumors of the Upper Stomach: Preliminary Results[Show abstract] [Hide abstract]
ABSTRACT: Gastrointestinal stromal tumors (GISTs) are rare neoplasms with malignant potential. Surgery is the definitive management for resectable nonmetastatic lesions. Although minimally invasive resection has been established for GISTs, it is still considered unfeasible when tumors are near the esophagogastric junction. This study aimed to compare the relative efficacy of gasless laparoscopy-assisted (GLA) and open approaches for resection of GISTs. Between January 2006 and December 2008, 28 consecutive patients undergoing surgery for upper GIST were reviewed retrospectively. Among these patients, 15 underwent GLA procedures and 13 underwent open surgeries. Patient demographics, comorbidities, and tumor characteristics (mean tumor size and prognosis) were similar for both groups. All patients underwent wedge resection. The mean operating time (129.6 versus 110.8 minutes), mean estimated blood loss (35.5 versus 40.3 mL), mean day of first flatus (2.7 versus 3.2 days), mean tumor size (2.5 versus 2.6 cm), and tumor prognosis or complication rate (13.3% versus 7.7%) between the GLA and open surgery groups were not significantly different. The length of maximal wound (P < 0.001), visual analog scale on postoperative days 1 (P = 0.001), 2 (P = 0.001), and 3 (P = 0.001), the mean time for resuming oral intake (P = 0.028), and the length of hospital stay (P = 0.005) in the GLA group were significantly lesser than the corresponding values in the open surgery group. None of the patients had dysphagia or died. GLA method is a safe and feasible procedure for resecting GISTs of the upper stomach. In addition, it offers better cosmetic results, less pain, and faster recovery.Journal of Laparoendoscopic & Advanced Surgical Techniques 10/2010; 20(9):725-9. DOI:10.1089/lap.2010.0231 · 1.19 Impact Factor
Article: Technical Innovation: Gasless Laparoscopic Hepatectomy Using Self-Designed Abdominal Lifting System[Show abstract] [Hide abstract]
ABSTRACT: In this article, we describe a new technique for performing a laparoscopic-assisted hepatectomy, using a self-designed abdominal wall-lifting systems. We used this system for 5 patients; 2 were left lateral segmentectomy, 1 was S6 segmentectomy, and 1 was S8 wedge resection, and the other was an extended left hepatectomy. This procedure can minimize the length of the wound, while avoiding the lethal complications associated with the pneumoperitonium. This device and technique can also provide a bridge for young or less-experienced surgeons to be familiar with advanced laparoscopic surgery from open surgery. Also, the patients under such an operation were found to have fast postoperation recovery and short hospital stay.Journal of Laparoendoscopic & Advanced Surgical Techniques 09/2009; 19(4):541-4. DOI:10.1089/lap.2008.0435 · 1.19 Impact Factor
Article: Effects of parenteral glutamine supplementation on modulating the immune response in rats undergoing a total gastrectomy.[Show abstract] [Hide abstract]
ABSTRACT: The present study investigated the effect of parenteral glutamine (Gln) supplementation on cellular adhesion molecule expression and release of chemokines responsible for inflammatory cell recruitment in rats undergoing a total gastrectomy. Normal rats with internal jugular catheters were assigned to one control group and two experimental groups and received total parenteral nutrition (TPN). A total gastrectomy was performed in the experimental groups, whereas the control group received a sham operation (Sham). The TPN solutions were isonitrogenous and identical in nutrient composition except that the Sham group and one of the experimental group received conventional (Conv) TPN solution, whereas the other experimental group received 25% of the amino acid nitrogen as Gln. Half of the rats in each group were killed 1 or 3 d after surgery or the Sham to examine their immune response. The results showed that the surgery produced higher polymorphonuclear leucocyte CD11b/CD18 expressions, and Gln supplementation lowered CD11b/CD18 expressions compared with the Conv group post-operatively. The levels of monocyte chemotactic protein-1 and macrophage inflammatory protein-2 in peritoneal lavage fluid were higher in the Gln group than those in the Conv group 1 d post-operatively; these chemotactic proteins had returned to the levels comparable with those in the Sham group on post-operative day 3. These results suggest that Gln supplementation attenuated polymorphonuclear leucocyte integrin expression. In addition, Gln-enriched parenteral nutrition induced an earlier more intensive and rapid immune response to injury than the Conv parenteral nutrition after a total gastrectomy.The British journal of nutrition 03/2009; 102(4):520-5. DOI:10.1017/S0007114508207257 · 3.34 Impact Factor
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ABSTRACT: Intussusceptions of the small bowel, along with multiple intraluminal metastatic tumors, were noted during surgery. A segmental resection of the small bowel was performed, and the histologic diagnosis of metastatic melanoma was made. Long-term survival remains poor; therefore, complete surgical resection of macroscopic tumors remains the best treatment of choice.American journal of surgery 06/2008; 196(3):e1-2. DOI:10.1016/j.amjsurg.2007.05.062 · 2.41 Impact Factor
- Surgery 06/2008; 143(5):693-4. DOI:10.1016/j.surg.2007.05.013 · 3.11 Impact Factor
Article: Gasless laparoscopy-assisted subtotal gastrectomy for early gastric cancer: A novel minimally invasive surgery[Show abstract] [Hide abstract]
ABSTRACT: Due to the highly invasive nature of traditional surgery and the limitation of gas-filling laparoscopic surgery in gastric cancers, we developed a new method of gasless laparoscope-assisted subtotal gastrectomy (GLASG). This study investigated the technique and clinical results of this procedure and compared it with traditional radical subtotal gastrectomy (TRSG) for early gastric cancers. From December 2004 to January 2006, 41 patients diagnosed with early gastric cancer were included in the study. All cases underwent subtotal gastrectomy with standard radical lymph node dissection. Twenty patients underwent GLASG, whereas the other 21 patients underwent TRSG. In the GLASG group, we performed our newly developed method using three working ports created at the bilateral subcostal and umbilicus, which provided a 3-dimensional sensation by direct vision through a minilaparotomy and laparoscopic view simultaneously. B-II gastrojejunostomy reconstruction was performed by intracorporeal anastomosis using an endostapler. The TRSG group underwent the standard open method used for gastric cancer. Preoperative characteristics and postoperative recovery between the two groups were compared. The operative time was comparable between the two groups, but the bleeding was significantly less severe in the GLASG group. Postoperative pain was significantly less in the GLASG group, as well as body temperature from postoperative day 2 to 7. The number of days to first flatus, first oral intake, and discharge were all significantly less in the GLASG group. No major complications were noted in either group. GLASG may be a feasible and safe procedure for early gastric cancer. Gasless laparoscopic gastrectomy has the advantages of less pain, better cosmetic outcome, and earlier recovery. The newly developed gasless environment may hybridize the advantages of open method and pure laparoscopic method.Journal of Gastrointestinal Surgery 05/2008; 12(4):695-700. DOI:10.1007/s11605-007-0339-0 · 2.39 Impact Factor
Top Journals
National Taiwan University
T'ai-pei, Taipei, Taiwan
- Graduate Institute of Toxicology
National Taiwan University Hospital
T'ai-pei, Taipei, Taiwan
- Department of Surgery
Buddhist Tzu Chi General HospitalT'ai-pei, Taipei, Taiwan


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Thursday, October 16, 2014
Rush Reunion 2015
The Rush Reunion 2015 date has been set. The dates are July 25, 2015 - Aug. 1, 2015. The itinerary hasn't been set yet for daily events but it will be shortly. If you have suggestions please send them in. Also any photos, stories etc that you would like added to the family tree or the family history book please let me know. Over the last 4 years we have lost some of the family but we have memories that will last a lifetime. Also there have been some new additions to the family and we would like to welcome them also. I hope each of you are doing well and look forward meeting may of you in 2015.
Posted by Michelle at 6:55 PM 2 comments:
Tuesday, July 1, 2014
Rush Reunion 2015 Benedicta, Maine
Every five years, the Rush Family Reunion is held in Benedicta for the descendants of Johann Diederich Rasche, 1800-1874, and Sarah Theresa Schmidt, 1812-1856, also known as John D. Rush and Sarah T. Smith.
Johann came to the United States about 1833 from Stelle in the Kingdom of Hannover. His wife, Sarah, came to the U.S. with her parents in 1827 from Alsace, France.
They had 13 children, 12 of whom lived long lives, according to Richard D. Kelly Jr. The 12 each married and gave Johann and Sarah a total of 109 grandchildren, so there are numerous descendants.
When most folks think of Benedicta, they think Irish, Kelly pointed out, but there also were three German families who settled in Benedicta in the 1830s — the Rasches (Rush), the Rövers (Rivers) and the Schmidts (Smith).
Posted by Michelle at 6:47 PM 3 comments:
Photos from the last Rush Reunion
Posted by Michelle at 6:45 PM No comments:
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You may notice on your Windows Server 2003 servers monitored with OpsMgr 2012, that some class properties on Windows Computer instances are not discovered. Organizational Unit, IP Address, Logical Processor, Physical Processor, etc.
Windows Server 2003 machines need a hotfix for this to work, due to some changes that were apparently made to the Windows Computer discovery script in OpsMgr 2012.
The hotfix is http://support.microsoft.com/kb/932370 "The number of physical hyperthreading-enabled processors or the number of physical multicore processors is incorrectly reported in Windows Server 2003"
Once you apply this, changes are made to the Win32_ComputerSystem and Win32_Processor classes in WMI to make them similar to Windows Server 2008 and later. Makes me think that the SCOM team isn't testing a whole lot with Windows Server 2003 anymore.
After applying the hotfix and a reboot, the info comes in quickly.
Thanks to PFE Greg Davies for bringing this to my attention, and credit goes to Cameron Fuller and RobK for finding the solution. Cameron has a quick way of using groups to find out who needs this hotfix quickly.
Apparently Daniele was recommending this ages ago – I am just catching up to these guys.
Thx for bring this up Kevin....Sorta makes u wonder what else may be broken.
Glad the decision was made to run 2012 in parallel with 2008R2 at our installations.
John Bradshaw
hoo-boy, telling customers that they need to patch *their* servers because something isn't working right on SCOM is not going to go over very well.....plus this hotfix requires a reboot. Double-whammy..... :(
Can we hope that Microsoft will incorporate this hotfix into a future Service Pack for Windows 2003?
@Wilson -
While I can totally understand your perspective, it is very common for monitoring platforms to require OS level hotfixes to work correctly. Just look at my hotfix page and you can see many many required or strongly advised hotfixes which should be applied to servers no matter what monitoring tool you are using.
As to the service pack, I'd seriously doubt we are going to see another major SP for a 10 year old operating system, that will be N-3 (3 versions old)... but thats just a guess.
My recommendation is for customers to simply add this hoptfix into their monthly patching cycle for their servers, that they already are performing.
Kevin, I see that you said "After applying the hotfix and a reboot, the info comes in quickly." did you have to do anything else? I have installed the patch on several servers and I am not having any luck getting the info to populate.
@Joey -
Nope - I just installed the hotfix, then rebooted, and upon service startup the SCOM agent will run its discoveries. Bounc the SCOM agent service and see if it speeds up.
I just came across this problem also, but not because details were not discovered. After moving a couple of servers to a new subnet the IP address was not updated. In most cases (not all) the IP address and AD Site are discovered. OU is never discovered for 2003 servers.
After digging through the discovery script and finding the faulty WMI query it make sense that the IP address and potentially other attributes will not get changed. What I am confused about is how they got there in the first place. It might make more sense if this was an upgrad from 2007 but the management group is a clean install of 2012. We are multihoming a number of agents so maybe cookdown is playing a role.
Any thoughts?
@Rob - that sure sounds odd.... each management group does not cook down between them - they are distinct.
My 2003 agents do not report their Logical and Physical Processors, but I am still able to view performance data like % Processor Time -Total. Anyone know why that is? Just wanted to know if I can hold off until our next patch maintenance...
@ntguru5 -
That's normal. There is no issue reading simple perfmon data. The issue is discovering specific information out of WMI. The %Processor Time is collected against the Windows Server 2003 Operating System class, which is discovered.
Thanks Kevin for clarifying that for me and also the quick response!
I have a strange issue where the OU information in the SCOM console is changing to just the top level of the domain, and not the full path. Where does SCOM get this information from so I can investigate?


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The Magazine
Budget Gamesmanship
The Republicans are winning the deficit debate.
Apr 25, 2011, Vol. 16, No. 31 • By TOD LINDBERG
Except that this great debate is occurring at a time of generally acknowledged serious fiscal imbalance and economic weakness. The president has conceded his concern. He tried to be blasé about it in the first move of this year's budget game, but it didn't work out for him. He agreed in the end to accept a budget deal for this year with spending cuts. He says there are other areas that can be cut (even if he doesn't mean it or doesn't want to act on it). It will be up to Republicans to press him by putting forward spending reductions outside the context of a grand deal. They will have ample opportunity.
True, the result will not be entitlement reform on a Ryanesque scale. And whatever Republicans propose, Obama will deem excessive. But the president will find a "no cutting" position exceedingly difficult to defend. The most likely outcome will be an argument over how much gets cut. The terms of reference of such an argument will be a powerful indicator of how badly the liberal Democratic position has deteriorated.
That's not to say that profligacy didn't have its day. With a little help from the outgoing Bush administration, the government burned through several trillions in borrowing that might otherwise have helped cushion the Baby Boom retirement bulge. But the current political environment seems to be prohibitive for those who would like to deny the reality of the fiscal problem. Obama tried that, and it was a losing strategy. He will now have to cut more spending—while making the case for a very large tax increase that is either going nowhere or is going to land by default on everybody who enjoyed lower rates thanks to George W. Bush.
The left and right poles of the debate are well-positioned for Republicans.
Tod Lindberg, a research fellow at the Hoover Institution and editor of Policy Review, is a contributing editor to THE WEEKLY STANDARD.
Recent Blog Posts
The Weekly Standard Archives
Browse 19 Years of the Weekly Standard


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Make the information in your Access database more transparent and easier to navigate with forms and reports. These Access tutorials show how to use forms and reports to control the display of data and gather parameters for queries.
Learn to create and manage data, maps, and analytical models with ArcGIS.
Create a better user experience for your Access database. Make it faster, more efficient, and fun with these power tips.
Find out how to get more out of your Access database, using queries—tools that help you translate complex raw data into information you can use to make better decisions.
Shows how to manage data entry and reporting tasks using Access 2007.
Shows how to manage data entry and reporting tasks using Access 2010.
Create and leverage real-world queries and turn raw data into usable information.
Creating and leveraging real-world queries and turning raw data into usable information.
"This $25 was the BEST I could have ever spent! I have spent hours relearning things I had forgotten and solidified my confidence in what I do know." —Claudia W.
more from our members »


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The trade deadline is today and here are some deals that have happened in the last 24 hours.
- The Blue Jays first traded outfielder Travis Snider to the Pirates for right-hander Brad Lincoln
- The Blue Jays also traded Eric Thames to the Mariners for Steve Delabar
- The Mariners traded Brandon League to the Dodgers for a pair of minor leaguers: outfielderLeon Landry and right-hander Logan Bawcom
- The Cubs trade Paul Maholm and Reed Johnson to the Braves for right-handed pitchersArodys Vizcaino and Jaye Chapman
- The Cubs traded Geovany Soto to the Rangers for Jacob Brigham
Here's the worst story of the day.
- One of the Red Sox players most likely to get traded, Ryan Sweeney, punched a door last night and broke his hand (most likely) the night before the deadline. He is getting put on the DL stopping any trade he might be in. That's one way to block a trade.
Read more breaking news at Sports Page
Play Our Fantasy Game Today and Try Your Hand at Winning $250 for FREE


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Saddle up for Halloween fun in this fantastic and officially licensed My Little Pony Pinkie Pie Deluxe child costume. You'll surely win first prize in this pink dress complete with detachable tail, arm warmers, leg warmers and matching character headpiece.
Let your little kitten have a ball on Halloween when you dress her in the Playful Leopard Toddler Costume. This cute, leopard print dress features an attached tail and black skirt with pink trim, complete with a cat ear headband, matching leg warmers and a black choker.
Graze the neighborhood for candy on Halloween in style when you wear this Zebra Tutu Child Costume! Off the shoulder animal print tutu dress adds a splash of pink to mix up the traditional black and white look and comes with leg warmers, wristlets and ears.
The the award for most adorable monster goes to...your little girl when they wear this Aarg Monster Infant Costume. Yellow and pink hooded shrug comes complete with purple tank top, matching skirt and leg warmers.
You're everyone's worst nightmare in the Officially Licensed Freddy Dress Adult Women's Costume. Terrify children and adults alike when you wear this red and black striped skirt with shrug and matching arm and leg warmers, leather-like corset and iconic fedora hat.
This officially licensed Flintstones Pebbles teen costume has you dressed and ready for the Stone Age! Make no bones about it, this is one adorable outfit with a funky animal print top and sawtooth trim on the garments accompanied by a pink wig and matching leg warmers.


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Long-Run Structural Modelling
The paper develops a general framework for identification, estimation, and hypothesis testing in cointegrated systems when the cointegrating coefficients are subject to (possibly) non-linear and cross-equation restrictions, obtained from economic theory or other relevant a priori information. It provides a proof of the consistency of the quasi maximum likelihood estimators (QMLE), establishes the relative rates of convergence of the QMLE of the short-run and the long-run parameters, and derives their asymptotic distributions; thus generalizing the results already available in the literature for the linear case. The paper also develops tests of the over-identifying (possibly) non-linear restrictions on the cointegrating vectors. The estimation and hypothesis testing procedures are applied to an Almost Ideal Demand System estimated on U.K. quarterly observations. Unlike many other studies of consumer demand this application does not treat relative prices and real per capita expenditures as exogenously given.
If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
As the access to this document is restricted, you may want to look for a different version under "Related research" (further below) or search for a different version of it.
Volume (Year): 21 (2002)
Issue (Month): 1 ()
Pages: 49-87
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References listed on IDEAS
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- M. Hashem Pesaran & Ron P. Smith, 1998. "Structural Analysis of Cointegrating VARs," Journal of Economic Surveys, Wiley Blackwell, vol. 12(5), pages 471-505, December.
- Pashardes, Panos, 1993. "Bias in Estimating the Almost Ideal Demand System with the Stone Index Approximation," Economic Journal, Royal Economic Society, vol. 103(419), pages 908-15, July.
- Donald W.K. Andrews, 1986. "Consistency in Nonlinear Econometric Models: A Generic Uniform Law of Large Numbers," Cowles Foundation Discussion Papers 790, Cowles Foundation for Research in Economics, Yale University.
- Phillips, P C B, 1991.
"Optimal Inference in Cointegrated Systems,"
Econometric Society, vol. 59(2), pages 283-306, March.
- Peter C.B. Phillips, 1988. "Optimal Inference in Cointegrated Systems," Cowles Foundation Discussion Papers 866R, Cowles Foundation for Research in Economics, Yale University, revised Aug 1989.
- Potscher, Benedikt M. & Prucha, Ingmar R., 1994. "Generic uniform convergence and equicontinuity concepts for random functions : An exploration of the basic structure," Journal of Econometrics, Elsevier, vol. 60(1-2), pages 23-63.
- Johansen, Soren, 1991. "Estimation and Hypothesis Testing of Cointegration Vectors in Gaussian Vector Autoregressive Models," Econometrica, Econometric Society, vol. 59(6), pages 1551-80, November.
- Johansen, Soren, 1995. "Identifying restrictions of linear equations with applications to simultaneous equations and cointegration," Journal of Econometrics, Elsevier, vol. 69(1), pages 111-132, September.
- A Garratt & K Lee & M Pesaran & Yongcheol Shin, 2004.
"A long run structural macroeconometric model of the UK,"
ESE Discussion Papers
35, Edinburgh School of Economics, University of Edinburgh.
- Anthony Garratt & Kevin Lee & M. Hashem Pesaran & Yongcheol Shin, 2003. "A Long run structural macroeconometric model of the UK," Economic Journal, Royal Economic Society, vol. 113(487), pages 412-455, 04.
- Garratt, A. & Lee, K. & Pesaran, M. H. & Shin, Y., 1998. "A Long-run Structural Macro-econometric Model of the UK," Cambridge Working Papers in Economics 9812, Faculty of Economics, University of Cambridge.
- Pesaran, M. H. & Smith, Ron P., 1998. "Structural Analysis of Cointegrating VARs," Cambridge Working Papers in Economics 9811, Faculty of Economics, University of Cambridge.
- Phillips, P.C.B., 1986.
"Testing for a Unit Root in Time Series Regression,"
Cahiers de recherche
8633, Universite de Montreal, Departement de sciences economiques.
- Peter C.B. Phillips & Pierre Perron, 1986. "Testing for a Unit Root in Time Series Regression," Cowles Foundation Discussion Papers 795R, Cowles Foundation for Research in Economics, Yale University, revised Sep 1987.
- Pesaran, M. H. & Shin, Y. & Smith, R. J., 1997.
"Structural Analysis of Vector Error Correction Models with Exogenous I(1) Variables,"
Cambridge Working Papers in Economics
9706, Faculty of Economics, University of Cambridge.
- Pesaran, M. Hashem & Shin, Yongcheol & Smith, Richard J., 2000. "Structural analysis of vector error correction models with exogenous I(1) variables," Journal of Econometrics, Elsevier, vol. 97(2), pages 293-343, August.
- Saikkonen, Pentti, 1993. "Estimation of Cointegration Vectors with Linear Restrictions," Econometric Theory, Cambridge University Press, vol. 9(01), pages 19-35, January.
- Pesaran, M.H., 1996.
"The Role of Economic Theory in Modelling the Long Run,"
Cambridge Working Papers in Economics
9612, Faculty of Economics, University of Cambridge.
- Pesaran, M Hashem, 1997. "The Role of Economic Theory in Modelling the Long Run," Economic Journal, Royal Economic Society, vol. 107(440), pages 178-91, January.
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"Fully Modified Least Squares and Vector Autoregression,"
Econometric Society, vol. 63(5), pages 1023-78, September.
- Peter C.B. Phillips, 1993. "Fully Modified Least Squares and Vector Autoregression," Cowles Foundation Discussion Papers 1047, Cowles Foundation for Research in Economics, Yale University.
- Donald W.K. Andrews, 1990.
"Generic Uniform Convergence,"
Cowles Foundation Discussion Papers
940, Cowles Foundation for Research in Economics, Yale University.
- Andrews, Donald W.K., 1992. "Generic Uniform Convergence," Econometric Theory, Cambridge University Press, vol. 8(02), pages 241-257, June.
- Engle, Robert F & Granger, Clive W J, 1987. "Co-integration and Error Correction: Representation, Estimation, and Testing," Econometrica, Econometric Society, vol. 55(2), pages 251-76, March.
- Johansen, Søren & Juselius, Katarina, 1992. "Testing structural hypotheses in a multivariate cointegration analysis of the PPP and the UIP for UK," Journal of Econometrics, Elsevier, vol. 53(1-3), pages 211-244.
- Saikkonen, Pentti, 1993. "Continuous Weak Convergence and Stochastic Equicontinuity Results for Integrated Processes with an Application to the Estimation of a Regression Model," Econometric Theory, Cambridge University Press, vol. 9(02), pages 155-188, April.
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Bangladeshi Migrants Risk High Seas and Smugglers to Escape Poverty
Though he is only 16 years old, Mohammad Yasin has been through hell and back. He recently survived a hazardous journey by sea, crammed into the cargo-hold of a rudimentary boat along with 115 others.
U.N. Chief Seeks Equity in Paris Climate Change Pact
When the 193-member General Assembly hosted a high level meeting on climate change Monday, Secretary-General Ban Ki-moon warned that any proposed agreement at an upcoming international conference in Paris in December must uphold the principle of equity.
Black Women in the Americas Launch Decade of Struggle
They say they are tired of waiting for justice after centuries of neglect and contempt due to the color of their skin. Black women leaders from 22 countries of the Americas have decided to create a political platform that set a 10-year target for empowering women of African descent and overcoming discrimination.


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31 year old man | Nashville, TN, USA | Seeking men 23-37
Never be bullied into silence...
I have a wicked sense of humor, an arsenal of one liner catch phrases, a purpose and passion for education, and a fun loving spirit. So why aren't I married yet? Perhaps I'm getting ahead of myself. Let's start with a celtics game or a drag show, a beer at a sports bar or a cocktail at a gay dive, or a coffee and slam poetry performance. I am varied and complicated, but that just adds to the excitement. I love of going out and exploring new parts of the city but have a terrible sense of directions, so experienced navigators wanted. Attracted to lots of types of guys, but typically those who have some confidence, a direction, and a socially conscious spirit catch my fancy. Bonus points for tattoos or guitar chops.
Camping , Coffee and conversation , Dining out , Music and concerts , Nightclubs/Dancing , Playing sports , Political interests , Volunteering , Watching sports
Tennis / Racquet sports
I exercise 1-2 times per week.
I like Dogs
Very Liberal
I like to be out and about with good friends and good laughs no matter where that is.
University of Vermont, Burlington, VT
Music: Anything with great lyrics and soul, singer-songwriters, socially conscious hip-hop, angst songs, NOT techno Movies: Dark Comedies and documentaries usually..action movies sometimes. TV shows: sports and bad reality TV
Big sports fan, politics nerd, volunteer, poetry writer, tennis player, and activist.
I just read Bill Clinton's new book..ha I know...who finds pleasure in these things? Also love David Sedaris and Josh Killmer-Purcell.
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|5'10" (177cms)
|5'7" (170cms) to 7'11" (241cms)
|Body type:
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|Black, Blue, Brown, Grey, Green, Hazel
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|Auburn / Red, Black, Light brown, Dark brown, Dark blonde
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I work in higher education administration.
|$50,001 to $75,000
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|Never Married
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