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Longitudinal Studies of Brain Structure and Function in MPS Disorders
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Neurobehavioral function and quality of life are compromised in many patients with mucopolysaccharidosis (MPS) disorders. The long-term goals of this research are to: 1) more accurately inform patients/parents regarding potential neurobehavioral outcomes; 2) develop sensitive measures of disease progression and central nervous system (CNS) treatment outcome; and 3) help clinical researchers develop direct treatments for specific brain structures/functions. The investigators hypothesize that specific and localized neuroimaging and neuropsychological findings and their relationship will be distinct for each MPS disorder. It is further hypothesized that without treatment, functions will decline and structure will change over time in a predictable fashion, and will be related to locus of abnormality and stage of disease.
Mucopolysaccharidosis Type I
Mucopolysaccharidosis Type II
Mucopolysaccharidosis Type VI
|Study Type:
|Study Design:
|Observational Model: Cohort
Time Perspective: Prospective
|Official Title:
|Longitudinal Studies of Brain Structure and Function in MPS Disorders
- Change in Cognitive Ability (IQ) [ Time Frame: Baseline, Year 1, Year 2, Year 3, Year 4 ] [ Designated as safety issue: No ]Age-appropriate IQ tests will be administered at baseline and during subject's annual visit.
- Change in Quality of Life [ Time Frame: Baseline, Year 1, Year 2, Year 3, Year 4 ] [ Designated as safety issue: No ]Age-appropriate Quality of Life measures will be administered at baseline and during subject's annual visit.
- Change in Neuropsychological Status [ Time Frame: Baseline, Year 1, Year 2, Year 3, Year 4 ] [ Designated as safety issue: No ]Memory, Attention, Visual Spatial, and Visual Motor functions will be assessed with age-appropriate measures administered at baseline and during subject's annual visit.
- Change in Emotional and Behavioral Health [ Time Frame: Baseline, Year 1, Year 2, Year 3, Year 4 ] [ Designated as safety issue: No ]Age-appropriate measures of emotional and behavioral health will be administered at baseline and during subject's annual visit.
- Change Shown in Magnetic Resonance Imaging of the Brain [ Time Frame: Baseline, Year 1, Year 2, Year 3, Year 4 ] [ Designated as safety issue: No ]Magnetic resonance imaging of each subject's brain will be performed at baseline and during subject's annual visit to acquire volumetric and diffusion tensor imaging (DTI) data. These data will be analyzed to identify any changes occurring over time.
- Change in Adaptive Functions [ Time Frame: Baseline, Year 1, Year 2, Year 3, Year 4 ] [ Designated as safety issue: No ]Vineland Adaptive Behavior Scales, a measure of communication, daily living skills, socialization and motor function, will be administered at baseline and during subject's annual visit.
|Estimated Enrollment:
|Study Start Date:
|September 2009
|Estimated Study Completion Date:
|August 2019
|Estimated Primary Completion Date:
|August 2019 (Final data collection date for primary outcome measure)
MPS IH (Hurler syndrome)
MPS IH (Hurler syndrome) patients who are undergoing hematopoietic cell transplantation, or have had transplant in the past
MPS I Attenuated
Patients diagnosed with either Hurler-Scheie or Scheie syndrome on Enzyme Replacement Therapy (ERT)
Patients with Hunter syndrome who are on Enzyme Replacement Therapy
Patients with Maroteaux-Lamy syndrome who have either had hematopoietic cell transplant, or are on enzyme replacement therapy
Detailed Description:
The mucopolysaccharidoses (MPS diseases) are lysosomal disorders (inborn errors of metabolism) that progressively affect most organ systems in the body, usually beginning in childhood. Recent treatment advances have produced amelioration of some of these malfunctions, but notably brain and bone have been difficult to effectively treat. This research addresses the brain abnormalities in the MPS disorders, about which little is known.
The objectives of this research are:
- to identify abnormalities of central nervous system (CNS) structure and function as well as to measure quality-of-life (QOL) in both treated and untreated MPS patients over time. The investigators will accomplish this through longitudinal studies of enrolled patients in designated centers in North America.
- to develop quantitative measurements of change, including direct measurement of neuropsychological function; surrogate MRI markers; and biomarkers to measure stage of disease and treatment outcomes.
- to examine the degree to which independent variables have an impact on both functional and structural outcome. Independent variables may include, but are not limited to: age at first treatment, severity of disease, types of medical abnormalities, nature of genetic mutation, medical events, and sensory abnormalities.
- to examine how treatments such as Enzyme Replacement Therapy (ERT), Hematopoietic Cell Transplant (HCT), substrate reduction, and other palliative and rehabilitative therapies differentially affect CNS structure and function, as well as the subject's quality of life.
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
Patients who have verified diagnosis of MPS I, II, or VI. There are no age limitations.
Inclusion Criteria:
- Diagnosis of MPS I, II, or VI
- Must be able to undergo neuropsychological testing and MRI examination
Exclusion Criteria:
Presence of:
- Dental braces or other implanted metal that are not safe for MRI scan
- Programmable ventriculoperitoneal shunt
- pacemakers unless documented to be MRI safe
- behavioral abnormalities precluding cooperation
- pregnancy
Please refer to this study by its ClinicalTrials.gov identifier: NCT01870375
|Contact: Kathleen Delaney
|United States, California
|Oakland Children's Hospital
|Oakland, California, United States, 94609
|Contact: Jo Ann Johnson 510-428-3885 ext 5421 firstname.lastname@example.com
|Principal Investigator: Paul Harmatz, M.D.
|University of California San Francisco
|San Francisco, California, United States, 94143
|Contact: Jueleah Expose-Spencer, MBA, MHCM 415-353-1248 email@example.com
|Principal Investigator: Morton J. Cowan, M.D.
|United States, Georgia
|Emory University
|Atlanta, Georgia, United States, 30033
|Contact: Stephanie Cagle, MS 404-778-8421 firstname.lastname@example.com
|Principal Investigator: Suma Shankar, M.D.
|United States, Minnesota
|University of Minnesota
|Enrolling by invitation
|Minneapolis, Minnesota, United States, 55455
|United States, New York
|New York University
|New York, New York, United States, 10016
|Contact: Marissa Ferraris 212-263-0139 firstname.lastname@example.com
|Principal Investigator: Heather Lau, M.D.
|Canada, Ontario
|Hospital for Sick Children
|Toronto, Ontario, Canada, M5G1X8
|Contact: Margaret Macrell, RN 416-813-8367 email@example.com
|Principal Investigator: Julian Raiman, M.D.
|Principal Investigator:
|Chester B. Whitley, M.D., Ph.D.
|University of Minnesota - Clinical and Translational Science Institute
|Study Director:
|Kathleen Delaney
|University of Minnesota - Clinical and Translational Science Institute
|Study Chair:
|Paul Harmatz, M.D.
|Oakland Children's Hospital
|Study Chair:
|Julian Raiman, M.D.
|Hospital for Sick Children, Toronto, Ontario, CA
|Study Chair:
|Morton Cowan, M.D.
|University of California, San Francisco
|Study Chair:
|Suma Shankar, M.D.
|Emory University
|Study Chair:
|Heather Lau, M.D.
|New York University
Additional Information:
Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|University of Minnesota - Clinical and Translational Science Institute
|ClinicalTrials.gov Identifier:
|NCT01870375 History of Changes
|Other Study ID Numbers:
|Study First Received:
|August 2, 2011
|Last Updated:
|December 4, 2014
|Health Authority:
|United States: Institutional Review Board
Keywords provided by University of Minnesota - Clinical and Translational Science Institute:
Maroteaux-Lamy syndrome
Mucopolysaccharidosis type VI
Hurler syndrome
Hunter syndrome
Hurler-Scheie syndrome
Scheie syndrome
Mucopolysaccharidosis type I
Mucopolysaccharidosis type II
Additional relevant MeSH terms:
Mucopolysaccharidosis VI
Mucopolysaccharidosis I
Mucopolysaccharidosis II
Carbohydrate Metabolism, Inborn Errors
Connective Tissue Diseases
Genetic Diseases, Inborn
Genetic Diseases, X-Linked
Heredodegenerative Disorders, Nervous System
Intellectual Disability
Lysosomal Storage Diseases
Mental Retardation, X-Linked
Metabolic Diseases
Metabolism, Inborn Errors
Nervous System Diseases
Neurobehavioral Manifestations
Neurologic Manifestations
ClinicalTrials.gov processed this record on July 05, 2015


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Now Jennifer has all she ever wanted, only to discover that there is a dark side to the glitz and number one hits. She will have to decide whether to sing her pain to a loving audience or find the courage to face the music in the private studio of her heart.
CBA best-selling author Julie L. Cannon is a native of Tennessee. She is the author of five published novels, including the award-winning Homegrown Series, described as 'Southern Fried Soul Food.' Her books include a finalist for the Townsend Prize for Fiction and for the SIBA Book Award. Truelove & Homegrown Tomatoes was named by Good Housekeeping as one of '20 Books to Tote on Vacation.' The Romance Readers' Book Club was chosen as a Target Breakout Book, and I'll Be Home for Christmas was named a Top Pick of Fall 2010 releases by CBA Retailers & Resources Magazine, in addition to being included in Nielsen's Top 50 Inspirational Titles. Along with writing novels and listening to Country music, Jule is an inspirational speaker and teaches various creative writing workshops. She lives in Watkinsville, Georgia, with her husband and youngest son.
Favorite Verse: Matthew 6:33 (KJV) "But seek ye first the kingdom of God, and his righteousness; and all these things shall be added unto you."
Please tell us a bit about yourself. I've had a love affair with words as long as I can remember. As a child I lived for those days of summer when we'd pile in the car and head to Mee-maw's farm in Armuchee, Georgia. It felt like pure heaven as us cousins rode horses bare-back down through the river bottoms, plucking blackberries and hunting arrowheads along the Ooestenaula River. In the evenings, I'd sit very still out on the porch, listening to my kinfolks indulging in that wonderful southern tradition of oral storytelling. Their stories were fabulous, truly stranger than fiction, and I was collecting them like lightning bugs.
Mama claims that as soon as I was able to string words together, I was telling my own stories. In grammar school, I began writing them down into little books crudely fashioned from construction paper. As I moved to middle school, then to high school, English teachers would put encouraging notes on my report cards, and for me, a particularly nerdy child, it was a way to hold my head up a bit even if I was picked last for teams during P.E..
In 1985, I earned a degree in Journalism from the University of Georgia, and landed in a string of torturous sales jobs. A closet writer, I still penned poems and stories every chance I got. Along came marriage, and a baby carriage, actually three of them, and yet, my insatiable need to create stories did not subside. In October of 1998, I entered and won a short story contest. To make a long story short, Hill Street Press, sponsor of the contest subsequently published my novel, Truelove & Homegrown Tomatoes in the spring of 2001. It became a southern bestseller and they sold the paperback rights to Simon & Schuster, who bought the rights to my second and third novels. Since then I've been published by Penguin, Summerside, and Abingdon Press. In addition to telling stories, my favorite things include growing flowers and tomatoes, reading novels, listening to country music, painting pictures, having coffee with friends, and spending time with my family.
What is your favorite Bible Verse: translation too please? Why?
It's changed many times over the years, and I'm sure it'll change again, but right now my favorite Bible Verse is Matthew 6:33, in the King James Version. "But seek ye first the kingdom of God, and his righteousness; and all these things shall be added unto you."
It's my favorite because it encapsulates the best way to live. If I stay focused on God, everything else just falls into place; spiritual, physical, emotional, and mental.
What was your inspiration to write Twang?
I'm often asked about where my story ideas come from, but it's a very mysterious process even to me when something gets transformed from an idea or thought into a story. I firmly believe the aptitude to write is a gift and entrustment from God and I take very seriously the commitment to co-create stories He won't be ashamed of. I love country music and I once read a comment from Merle Haggard about his music that struck me as how I feel about my writing. He said, "Music is a positive vibration we all need. It comes through me and I believe it comes from God. The Lord is just using me as an instrument and I'm just doing the best I can to respond to what He wants."
A lot of the plot for Twang fell in place when I read this quote by Conway Twitty, "A good country song takes a page out of somebody's life and puts it to music." I know that some singers do live out their songs. Take Tammy Wynette and D-I-V-O-R-C-E.
I thought about how certain country songs reduce me to tears. Songs such as "Jesus and Mama Always Loved Me," by Confederate Railroad. Then I got to thinking about the way people like to say, "To be a good country music artist, you gotta have tragedy in your life. Travail and hardship and all that stuff. You can't be happy and be a good country music singer."
So, I began to write about a very gifted young girl with a childhood straight out of a sad country song. Jennifer Clodfelter hightails it out of Blueridge, Georgia. She gets herself to Nashville, the so-called womb of Country music, determined to fulfill her destiny as a country music star. But, here's the thing about Jennifer, she is also determined to forget her dark and disturbing past. Her inner conviction is that she can bury her past and it won't hurt her.
How much of Twang comes from your personal experience?
How I wish I could say the singing, songwriting and playing the guitar did, but alas, every cent my folks shelled out for piano lessons went right down the drain. And, it wasn't the dysfunctional family. I had one of those childhoods you see in a Norman Rockwell painting. I used to joke my parents had halos floating above their heads, but I wasn't really joking. So, it wasn't the music and it wasn't the pitiful parents in Twang I could write from my own experience. But, like most people, at least most my age (pushing 50) there's plenty of things I'd like to bury and leave in the past.
But as a writer, I have found that those dark things, those unmentionable times I thought were purposeless, can become powerful stories if you show what you've learned, what sweet Grace you've tasted despite them. Plus, they can sure touch an audience.
In addition, the very act of writing (songs and stories) about experiences that were painful is cathartic. God can redeem the unredeemable. So, to the extent that God's used a lot of my dark times, redeemed them into art, that's what I drew from personally to write Twang.
How much research did Twang take?
I have three notebooks bulging with research! When I began writing, all I knew about the journey of a country music star was what I'd read in the tabloids. I knew nothing about writing songs. Thus, I spent hours studying the internet and reading books and biographies about the country music industry and stars and song-writing. But the pinnacle of all my research was a wonderful long weekend I spent in Nashville, Tennessee, sponsored by my publisher, Abingdon!
Ramona Richards, my editor, took me from Music Row to the Broadway honky-tonks to the Bluebird Café to Riverfront Park and the Cumberland River. We went to the Grand Ole Opry to hear Little Jimmy Dickens, and Vince Gill and Josh Turner. Josh sang one of my favorite songs in the world, Long Black Train. I filled an entire notebook on just that weekend tour, and since I wanted my story to be authentic in regard to Music City, I poured over those notes as I wrote.
What are the most interesting facts that you learned while researching and writing Twang?
The city of Nashville sits along the banks of the Cumberland River, a beautiful sight on my tour of Nashville. So, what knocked my socks off was hearing the horrible details about the May 2010 flood! Known as the "Thousand Year Flood," and called the single largest disaster to hit Tennessee since the Civil War, it was tragic. On May 1, 2010, it started to rain. It rained and rained and rained. Nearly 14 inches in two days, causing massive flooding. Homes were ruined, people evacuated, businesses shut down, schools cancelled. 21 deaths were recorded in Tennessee, and President Obama declared it a disaster area. What was really interesting was hearing how the city responded to this disaster. Tennessee is the Volunteer State, and if there was ever a time you could see people living that name out, it was after the flood. Country music artists and citizens alike joined together to rebuild Music City. Nashville celebrities such as Taylor Swift and Garth Brooks made significant donations to relief efforts, and the Country Music Association donated 100% of CMA Festival proceeds to flood relief. Hundreds of Nashvillians joined official crews helping families recover from the devastation. The country music community is very strong, they care, and the flood brought out the good in this community.
What are some of the challenges you face as an author?
It used to be laliaphobia, or the fear of public speaking. I thought authors were hermits who wrote their stories and then sent them out into the world via bookstores and libraries. However, it wasn't long after my first novel came out that I realized the error of that thinking! I had dozens and dozens of public speaking engagements to handle. And, by the grace of God (lots of PRAyer and PRActice), I'm now a professional (paid) keynote speaker, a writing workshop instructor, and I appear at numerous author seminars, on panels, etc…
My current biggest challenge is probably dealing with new technology. The opportunities for social-networking and social media increase daily and it can feel overwhelming. I try to keep up with all the new ways to interact with fans, fellow authors, and students in my writing classes. What aspects of being a writer do you enjoy the most?
I literally lose myself when I'm telling stories. I'm lifted up out of reality, and hours can fly by if a scene is going well. Writing is my passion/obsession and my bliss, my gift from God. What I loved about Twang was that it gave me the perfect excuse to read bios about my favorite artists – from Tammy Wynette to Alan Jackson to Faith Hill. I got to sit around listening to Josh Turner and Vince Gill and Blake Shelton, all in the name of research!!
What message would you like your readers to take from reading Twang?
That in the long run, it's very unhealthy to bury things. If you do it in the right way, i.e. with God's help, it's cathartic to pull things up and look them in the eye. Sometimes it even helps to write about them. God is in the business of redeeming the unredeemable.
What do you do to get away from it all?
I like to hang out with my family. Spending time with them is my favorite thing, even if it's just a walk through the woods or sharing a meal. I also adore going to the beach, reading fiction, listening to country music, actually lots of different types of music, drinking coffee with friends, and people watching and ….
Is there anything else you'd like to add?
Uhm, yes! The Catawba/Catalpa worm scene came from one of my personal journals. Brad Paisley said, "As a songwriter heartbreak is important."
Miranda Lambert said, "Being happy is horrible for songwriting, especially for country music. We just want to write about leaving and sadness."
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Programs aim to increase appetite for locally made food: Some say cost is a factor in supporting local farmers
By Sam Boykin When musician Jack Johnson rolls into town Sunday for his concert at the Verizon Wireless Amphitheater, he'll be urging his fans to support family farmers and to eat locally grown food. While a lofty goal that would benefit the Charlotte metro area's economy and health, it's also easier said than done. Today, when many folks are strapped for cash and time, it can be tempting to swing into the nearest fast-food drive-in and get dinner for a couple of bucks. But there are a growing number of Charlotte restaurants, farmers markets and organizations trying to make eating healthier easier — although some lament that at times it can be cost-prohibitive to put local items on their menu. "Unfortunately, I can't find a lot of local meat products that I can affordably put on my menu," said Bruce Moffett, owner and chef of Barrington's restaurant. Moffett uses fresh, locally grown fruits and vegetables at the Charlotte restaurant, "but you have to walk that fine line between running a business and putting a roof over your family's head and supporting local farmers." To help spread his "eat local" message during his 31-city tour, Johnson partnered with the Eat Well Guide, a New York-based nonprofit and online directory for anyone in search of fresh, locally grown and organic food in the United States. The Eat Well Guide has put together guides for dozens of U.S. cities, including Charlotte.


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Cloud Architect - DevOps
Ukraine - Last active: 1 day ago - Tests: 6 - Portfolio: 5
System and network expert with strong work ethic and large experience in various IT fluids. Team player in big and small project - join fast and effective cooperate with different professionals. 13 year - total IT experience. 7 year - network and system administrator 5 year - Cloud expert 3 year - Streaming expert Last two year - active freelancer experience Streming Wowza, nginx-rtmp Scripting Python,Chef, PowerShell, PHP Deployment Chef, Capistrano, Puppet MySQL, Cassandra, MSSQL, Postgresql, MongoDB CouchDB WWW Apache,Tomcat, Nginx, IIS, LightHTTPd, HAProxy, Squid, Mail Sendmail Exchange Postfix Qmaill pop3 imap Monitoring Nagios Casti Zabix Windows Server 2008 R2 2003 2000 NT, Linux Debian Ubuntu RadHat CentOS SUN Oracle Solaris, BSDi, FreeBSD NAS, SUN, iSCSI, Big data backup DNS, DHCP, SMTP, SNMP H323,SIP, Asterix, Elastic, FreePBX, MySQL MSSQL Oracle Virtualizations. VmWare VSphere ESXi XEN KVM Project manager, Web Optimization, High Availability, Load Balancing Live Streaming solution. Video on Demand, IP TV, Media Server,
- Linux System Administration
- Apache administration
- Wowza Media Server
- LAMP Administration
- Nginx
- Unix System Administration
- Video Streaming
- Amazon EC2
- MySQL Administration
- Microsoft Windows Powershell
- DevOps
Associated with: emyoli Agency
Senior UNIX System Engineer, LAMP, LEMP, Network Security, Cloud.
United States - Last active: 4 days ago - Tests: 7 - Portfolio: 1
Expert UNIX system administrator and network engineer. Got a problem? I can solve it! For more than 15 years I have been the I.T. backbone and support for many online companies. I use the most up to date standards for any project I am involved in. I work extremely quick and efficiently. If you have a problem let me help you solve it. OS: Linux - Expert, FreeBSD - Expert, AIX - Expert, HP-UX - Expert, Macintosh OS/X - Expert, Windows Server - Proficient Cloud services: AWS, Rackspace, OpSource, Linode Web servers: Apache, Nginx, Tomcat Database servers: Mysql, Postgresql Monitoring: Nagios, Monit, Munin, Cacti Scripting: bash, perl, shell Virtualization: OpenVZ, Xen, SolusVM Mail servers: Postfix, Exim, Sendmail, Dovecot Control panels: cPanel, Plesk, Direct Admin, Webmin/Virtualmin, ISPconfig, OpenPanel Other: standard network services (DNS, DHCP, LDAP, Samba, SVN/Git, http proxy, jabber, backups, monitoring etc), firewalls (iptables, ipfw, pf)
- Network Administration
- Technical writing
- Data Entry
- CPanel
- Plesk
- Nagios
- WordPress
- Microsoft Excel
- Microsoft Word
- Adobe Dreamweaver
- Apache administration
- FreeBSD
- OpenBSD
- Linux System Administration
- Solaris Administration
- Rackspace Cloud Servers
- Exim
- Postfix SMTP Server
- Bash
- Unix shell
- Operating Systems Development
- Amazon EC2
- Amazon Web Services
- Eucalyptus Cloud
- CentOS
- LAMP Administration
- MySQL Administration
- phpMyAdmin
- Domain Migration
- Apache Tomcat
- Load Balancing
- Virtualization
- WordPress e-Commerce
- Joomla!
- Magento
- Git
- GitHub
- Apache Subversion (SVN)
- PCI Compliance
- Mac OS App Development
Associated with: Bass Designs Agency
Senior PHP Developer / Magento Expert
Poland - Last active: 4 days ago - Tests: 2
Hey there. Let me introduce my self. I work as web-developer during last 6 years and I learn programming sciences for a 12 years. Magento is my main are of expertise because I used to work in Magento inc. during 2 years.
Senior Systems/Business Analyst (15 years Exp.)
Brazil - Last active: 07/18/2013 - Tests: 2 - Portfolio: 6
Experienced Business and Systems Analyst, J2EE Certified Architect and Programmer. Post Graduate degree in Web-Based Software Development. Have been working with system development for the last 15 years, 8 of it eliciting requirements and building knowledge base for IT systems. Expertise in business, functional and technical levels. Also a specialist in requirements management, traceability, impact analysis and reverse engineering from source code. Strong ability to communicate with developers, management and customers, to keep every party at the same page, while detailing and approving the given solution. Technical Writing skills and 4 years work using English. Also a committed and collaborative professional who fits very well with the culture of remote teamwork. Primary services : ► System design using UML 2.0 diagrams (structure and behavior) : Use Case, Class, Sequence, Component, Deployment. ► Business process modeling using BPMN 2.0 ► Requirements gathering to use cases and user stories. ► Software Requirements Specification ► Agile-related: Product backlog, sprint planning, sizing, review and management. ► Requirements management and Integrated Change Control ► Create traceability between documentation and source code ► Reverse engineer legacy code to documentation ► Work in Strategic Planning and Project Management areas
- Business Process Modeling
- Java
- Business Analysis
- Requirements analysis
- Technical writing
- Technical Documentation
- Requirement Management
- Rational Unified Process (RUP)
- Project management
- Strategic planning
- Scenario Planning
- Oracle PL/SQL
- JavaScript
- Enterprise JavaBeans (EJB)
- JBoss Seam
- Hibernate
- Apache Struts
- JMeter
- JavaServer Faces (JSF)
- Java Servlets Development
- Selenium WebDriver
- Selenium
- Apache Subversion (SVN)
- Agile software developmennt
- Scrum
- JDeveloper
- Eclipse
- Sparx Systems Enterprise Architect
- IBM Rational Rose
- IBM WebSphere
- JBoss
- NetBeans
- Oracle WebLogic
- Internet Information Services (IIS)
- Apache Ant
- Apache administration
- Oracle database
- MySQL Administration
- PostgreSQL Administration
- Microsoft SQL Server Programming


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BERLIN — A German court on Tuesday threw out the case against a former SS man accused of involvement in the largest civilian massacre in Nazi-occupied France, saying there was not enough evidence to bring the 89-year-old to trial.
Cologne resident Werner C., whose last name has not been revealed in accordance with German privacy laws, was charged with murder and accessory to murder in connection with the 1944 slaughter of 642 civilians in Oradour-sur-Glane in southwestern France.
BERLIN - Air France and Germany's two largest airlines on Wednesday canceled more flights to Tel Aviv because of safety concerns amid the fighting between Israel and Hamas.
BERLIN (AP) - A 94-year-old man deported from the U.S. for lying about his Nazi past is unfit for trial on allegations that he was an accessory to thousands of murders as an SS guard at Auschwitz, a German court said Friday.
NAIROBI, Kenya - Kenya's president proclaimed victory Tuesday over the terrorists who stormed a Nairobi mall, saying security forces had "ashamed and defeated our attackers" following a bloody four-day siege in which dozens of civilians were killed.
BERLIN — Rochus Misch, who served as Adolf Hitler's devoted bodyguard for most of World War II and was the last remaining witness to the Nazi leader's final hours in his Berlin bunker, has died. He was 96.
KABUL, Afghanistan - A Taliban attack at the gates of the Afghan presidential palace cast a cold light Tuesday on the course of a war that Washington remains committed to ending.
BERLIN - As a 22-year-old German army lieutenant, Ewald-Heinrich von Kleist volunteered to wear a suicide vest to a meeting with Adolf Hitler and to blow himself up along with the Nazi dictator.
BERLIN - German pastor Gabriele Stangl says she will never forget the harrowing confession she heard in 1999. A woman said she had been brutally raped, got pregnant and had a baby. Then she killed it and buried it in the woods near Berlin.
BERLIN — Germany has launched a war crimes investigation against an 87-year-old Philadelphia man it accuses of serving as an SS guard at the Auschwitz death camp, The Associated Press has learned, following years of failed U.S. Justice Department efforts to have the man stripped of his American citizenship and deported.
Johann "Hans" Breyer, a retired toolmaker, admits he was a guard at Auschwitz during World War II, but told the AP he was stationed outside the facility and had nothing to do with the wholesale slaughter of some 1.5 million Jews and others behind the gates.
BERLIN — Rabbi David Goldberg had performed about 25 ritual circumcisions this year before a regional court ruled in June that the practice amounted to causing criminal bodily harm.
Despite the decision, he expects to perform the same number in the second half of the year.
"I haven't changed anything," said Goldberg, one of Germany's few mohels — a person trained in the Jewish ritual of circumcision.
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Cambridge, MA (PRWEB) August 26, 2014
The 20 ambassadors representing the ALS Therapy Development Institute's Young Faces of ALS (YFALS) community issued the following statement on Facebook today regarding the global Ice Bucket Challenge movement bringing awareness and driving new funding specifically for ALS research:
"Who would have thought that a bucket of water and some ice would raise all this awareness and funding toward ALS research! We each, together with our families, and on behalf of the entire ALS community, would like to express our deep gratitude to everyone who has accepted the Ice Bucket Challenge so far and encourage people to stay involved in the ultimate challenge to end ALS. Every time a person accepts the Ice Bucket Challenge and posts it on Facebook, Twitter, Instagram or YouTube, you give us new strength and hope. Every donation is moving the needle on important research leading to the development of effective treatments and a cure for ALS. Thank you!"
To see who YFALS Ambassadors have challenged to accept the Ice Bucket Challenge, visit http://www.als.net/icebucketchallenge.
2014 Ambassadors:
To learn more about the YFALS community and the 2014 YFALS Ambassadors, please visit http://www.facebook.com/YoungFacesOfALS.
About ALS
Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease) is a progressive neurodegenerative disease that leads to paralysis, due to the death of motor neurons in the spinal cord and brain. There is no known cure for the disease. About 5,000 people in the US are diagnosed with ALS each year; the incidence is similar to multiple sclerosis. However, with no effective treatment, the average patient survives only 2-5 years following diagnosis. While exact figures are unknown, it is estimated that there are about 30,000 people in the US diagnosed with ALS today. The worldwide population of ALS patients is estimated at 450,000.
About ALS Therapy Development Institute (ALS TDI)
The mission of the ALS Therapy Development Institute (ALS TDI) is to discover and develop effective treatments for ALS patients today as soon as possible. ALS TDI is the world's largest independent ALS/MND drug development-focused nonprofit organization. In addition to more than 30 internal therapeutic aimed programs, the world's first nonprofit biotech partners with dozens of pharmaceutical and biotechnology companies worldwide in order to advance potential treatments into the clinic. Its lead ALS therapeutic candidate, Novartis' (Switzerland) Gilenya (TDI-132), is in Phase 2A clinical trial for ALS. For more information on its drug development programs, visit http://www.als.net.
About ALS TDI's Young Faces of ALS (YFALS)
ALS TDI's Young Faces of ALS (YFALS) program is driven by several ALS patients diagnosed with the disease before or around the age of 30, along with family members and friends of people living with ALS. The young men and women selected to lead the campaign are called "YFALS Ambassadors," and together they participate in awareness campaigns via the YFALS Facebook page, YFALS website, and within their communities. Additionally, these ambassadors hope to encourage greater action to support ongoing drug development at ALS TDI, which has the sole mission to discover and develop effective treatments for ALS patients today.
Media Contact: Mari Cody, ALS TDI, mcody(at)als(dot)net, 617-441-7220


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Kevin Paul tattooed a Peter Pan design on the star's arm but claims he told him not to have it done after he decided he hated it
The Imitation Game actor was joined by his stylish wife-to-be at the British Independent Film Awards
Gaga Face isn't the only sleb we've seen who looks like one of Walt Disney's creations
The screaming holiday makers had to be rescued by a second boat after their dive vessel got into trouble
The victim was left with two broken arms and head injuries
Soap favourite now treading the boards in Royal Shakespeare Company's Christmas panto as Captain Hook
Editor Ian Katz said he had dispatched a producer to take the pair out of the building through different exits
West Wales proves a huge thrill for Tom Bryant and his family
If you think that a trip to Disneyland Paris was just for the kids? Think again, says Mel Brodie
Plus The Best of Men, Jennifer Saunders: Back in the Saddle, Emmerdale, EastEnders and Coronation Street
Watch Daniel Craig pay a visit to Buckingham Palace for Danny Boyle's show-stopping London 2012 curtain raiser
Older cars are cheaper to fix and 10% less likely to break down than expensive new ones, a study out today reveals.
Something tells us Harry Derbidge wouldn't stand much of a chance against Phil, or Hook, or anyone for that matter.
You can check the solution for today's cryptic crossword by calling 0901 562 8767 (RoI 1550 927 614).
Kate Middleton may not have been at tonight's British Fashion Awards but the Duchess of Cambridge certainly pulled out all the fashion stops in luxe Brit' label Mulberry.
Victoria Beckham has touched down at Heathrow airport looking suitably stylish ahead of tonight's British Fashion Awards.
A tattoo of the tiny fairy Tinkerbell on Liz Clare's tummy is a poignant reminder of the love of her life.
RYAN RHODES first won the British light-middleweight title in 1996 – and the Peter Pan of boxing is still the No.
There's no doubt about it, Peter Pan collar dresses are having a fashion moment right now.
Disney artist Mary Blair has today been celebrated with a Google Doodle.
It can be a dog's life on the X Factor so the contestants took a break from rehearsals to enjoy some puppy love.
STARS including Bono, Anna Friel and Jerry Hall climbed into fancy dress for Bob Geldof's Peter Pan-themed 60th birthday party.
ACTRESS Joanna Lumley has launched a £4million campaign to save the home that inspired JM Barrie to create Peter Pan.
music legend Sir Cliff Richard has threatened to start his own radio station in a desperate bid to get his hits played on the airwaves.
OVER the years I have seen some pretty awful pantomimes, so the thought of witnessing David Hasselhoff and Louie Spence crucify Peter Pan at my local theatre wasn't an option.
'Yes, I've slapped his arse' says Louie
Veteran pop star Sir Cliff Richard is celebrating his 70th birthday with a private party and a day off from performing.
Since when did Peter Pan have a chest rug, isn't he supposed to be nine or something? Only kidding, only kidding – it's Ed Westwick, innit. We're such jokers.
Justin Bieber has set the record straight about his mum - saying rumours that she was offered 50,000 dollars to pose topless in Playboy "grossed" him out.


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GIS Specialist | GIS Analysis & Development
India - Last active: 2 days ago - Tests: 2 - Portfolio: 8
Specialized in development of customized full stack webGIS solutions. Worked in GIS environments like ESRI, Google Maps, Mapbox, Geoserver, Mapserver, QGIS. Front end mapping using OpenLayers, Leaflet, MapBox, Google Maps / Fusion Table, D3JS, RaphaelJS and so on. Well efficient with DBMS like Oracle, MS-SQL, PostgreSQL for spatial database management. and also offer consulting services in all phases of the entire webGIS project life-cycle.
Software Engineer
Pakistan - Last active: 1 month ago - Tests: 5 - Portfolio: 13
I have done bachelors in Software Engineering, I am very much enthusiastic to computer languages, by this to develop desktop, web and mobile applications. I am experienced enough especially in JAVA and Android development.
- Core Java
- Android App Development
- JavaScript
- Google Places API
- Facebook Development
Groups: PHPFox
PHPFOX Expert with 7 years of Experience
India - Last active: 4 days ago - Tests: 4 - Portfolio: 24
Over the last 7 years, I have developed a wide range of websites using HTML,PHP, PHPFOX,AJAX,JavaScript and MYSQL. I have done lots of phpfox customization works and ability to satisfy my clients. I also have some experience in the following areas: Ajax, OOPS, PAYPAL INTEGRATION, PAYMENT GATEWAY INTEGRATION, Wordpress, Joomla software design and testing.
- phpfox
- MySQL Administration
- WordPress
- Elgg
- CodeIgniter
- Paypal Integration
- Authorize.Net Development
- Facebook Development
- twitter api
- LinkedIn Development
- PhpBB
- jQuery
- Payment Gateway Integration
- Search Engine Optimization (SEO)
- iPhone App Development
- Android App Development
- PhoneGap
- Google Places API
- Google Maps API
Groups: Bluehost Developers and Designers, PHPFox
Associated with: phpmasterminds
Expert Android,iOS,Java,Swift developer.
Bangladesh - Last active: 3 days ago - Tests: 5 - Portfolio: 10
Expert Android and iOS app developer with 3+ years of experience. Also have proficient knowledge and working expertise of Java,Objective-C, Swift, C#,C++,Sql. Have a bachelor degree in computer science and technology from Bangladesh University of Engineering and Technology. Creative,hard working, passionate and committed software developer.Loves new challenges and opportunities. No compromise about the quality of service provided. Client's satisfaction is a priority.
- Android App Development
- Java
- .NET Framework
- Qt
- JavaScript
- Oracle database
- Oracle PL/SQL
- MySQL Administration
- SQLite Administration
- Google Analytics
- Google App Engine
- Google Apps
- Google Maps API
- GPS Development
- Localization
- Google Places API
- Image Processing
- SAP Crystal Reports
- Microsoft Exchange Server
- Socket Programming
- Artificial Intelligence
- Multithreaded Programming
- Video Streaming
- Database Modeling
- Data Structures
- Data Encoding
- Data Analytics
Groups: Corona Labs
Associated with: Dhrubok Infotech Services Ltd.
Expert iPhone/iPad/Android/Blackberry/C#/ASP.Net Developer
Pakistan - Last active: 12/20/2014 - Tests: 5 - Portfolio: 22
I have 6+ years of experience in mobile application development. Till now I developed 50+ iPhone/iPad/Android/Blackberry/Windows Mobile/Blackberry-Tablet apps. In addition to my development, I have more than 10 years experience of professional Web design/programming using ASP.Net, MS SQLServer, WPF, WCF, .Net Remoting, HTML, CSS, JSP, PHP, JavaScript, AJAX, JSON, RSS, MySQL, Web Services, API, Payment Gateway Integration. I am very fluent in Objective-C/Java /C# and C/C++ application development. I have made use of APIs of SNS(Facebook, Twitter etc.), Google Maps, GPS, In App Purchase, Dynamic contents update from web DB and more. The most important thing for me is a quick and quality work that the customer was satisfied. I specialize in making things intuitive, engaging and enjoyable. A prominent feature of my applications involves writing well organized code. I'm seeking opportunities to develop apps for you and your business.
- Objective-C
- iPhone App Development
- Android App Development
- BlackBerry JDE
- Windows Phone
- .NET Remoting
- Windows Presentation Foundation (WPF)
- Windows Communication Foundation (WCF)
- Transact-SQL
- CakePHP
- Amazon Web Services
- xml web services
- Google Maps API
- Google Places API
- Java
- iOS Development
- Blackberry app development
- Facebook Development
- twitter api
- iPad App Development
- Cocoa Touch
- Cocoa
- Cocos2d
- Multithreaded Programming
- Microsoft Visio
- Git
- Apache Subversion (SVN)
- Tortoise SVN
- Mac OS App Development
- Apple Xcode
- Apple UIKit Framework
- Twilio API
- SQLite Administration
- Visual Basic
Mobile and Desktop Developer
Turkey - Last active: 08/29/2014 - Tests: 7 - Portfolio: 5
Hi Clients, I am a mobile and desktop developer in Turkey. I have rich experiences for 6+ years in Mobile apps and Desktop apps. For last 6 years, I worked on many fields and developed many mobile and desktop apps. I always look for long term relationship and always try to make happy my clients with my skill. Also, I am a hard worker who work 10+ hrs per day and you will be able to touch me at any time you want via Skype or email. My skills and experiences are following 1) Mobile Applications - iPhone/iPad/iPod and Android Phone/Tablet - Web Service, Ajax, XML, JSON, RSS - Image and Video Processing/ Camera related/ Captioning/ Effects - MySQL SERVER, SQLite, HTML5, PHP, JSP - Facebook, Twitter , Instagram, Youtube - Google Map Service, Foursquare - CoreData, CoreGraphics, Animation - Twilio api, VOIP, Parse api ( parse.com) - QR code, Bar code scanning related apps 2) Mobile Games - Cocos2D, OpenGL, Corona, Unity3D - Box2D, Chipmunk - Game Center, In-App Purchase, Multiplayer Game - iAd, Adwirl, Admob, Chartboost, TapJoy, Cerebro - Flurry, Testflight 3) Desktop Applications - Microsoft Visual Studio 6.0 ~ 2013 - Linux gcc, g++ - QT (Linux and Windows) - Java - MySQL and SQL Server connection 4) Reverse Engineering - Reverse Windows PE files and Linux ELF files - Reverse Android apk files - Reverse Mac .app files and iOS .ipa files Let's success with me!!! Thank you.
Sr. Software Developer
United States - Last active: 09/27/2013
Ji Lucas is an mobile/internet entrepreneur whose approach strikes a harmonic blend of technology and philosophy. She is a huge proponent of Social media in general and a highly soughtafter speaker in Mobile Devices & Web 2.0 technologies. Ji has positioned herself as a true agent of change for progressive companies wishing to innovate, virally market, and build engaging and unforgettable experiences on Application.
iPhone App Developer, iPad App Developer and Android App Developer
Pakistan - Last active: 02/27/2014 - Tests: 17 - Portfolio: 12
I have been working on Mobile Apps since 6 years now since Apple Introduced its public APIs for the iOS. Mostly of the part of work is related to Mobile App Development and Server Side Development but as a personal hobby I also design beautiful user interfaces for Mobile Apps and Web Applications. Due to keen interest in UIs employers often ask me take whole project to do everything from UIs, App Development to API Development. All of the client whom I've worked so far are very happy with my work which you see by my feedbacks. Core Experiences and Expertise: - Core Location / GPS - MapKit - GeoLocations / Places API - AVFoundation API / Camera API - API Development and Integration to App - JSON / XML - Facebook API, Twitter API, Youtube API, LinkedIn API Integration, FourSquare API - iAds / AdMob Integration - Designig User Interfaces / User Experience Engineering - Core Data / SQLite - Memory Management - Developing Custom Controls - CoreAnimation API / Animations - File Uploads - RSS - Project Management - Successfully launching Project to Apple App Store / Google Play - Web Application Development - XHTML/CSS - PHP/MySQL - CodeIgniter/Yii - And Many More… What you can Expect from my side: - High quality end Products within deadlines - Meeting Crucial Deadlines - Available for Bug fixes and Future Updates - Always available to contact via Skype or Phone - Flexible to work in a Team or alone
- Objective-C
- iPhone App Development
- iOS Development
- API Development
- Mobile App Development
- Android App Development
- Windows Phone
- MySQL Administration
- CodeIgniter
- Yii
- FourSquare Development
- Facebook Development
- Adobe Photoshop
- jQuery
- WordPress
- Joomla!
- Google Places API
- twitter api
- Cocoa Touch
- Java
- Database design
- Project management
- User interface design
- Apache Subversion (SVN)
- Git
- Amazon EC2
- Amazon Web Services
Associated with: Creative Oxide
Web Developer asp.net - .net - C# - vb.net - SQL server - dropbox api
Egypt - Last active: 11/06/2014 - Tests: 8 - Portfolio: 8
over the last 5 years , I have developed websites using asp.net , c# , vb.net, sql server 2005,2008 , Ajax , JavaScript (JSON, Dom) , Css , jquery , jquery-UI I also have some experience in the following areas: OOP, and software design ,testing ,UML and DotNetNuke
- .NET Framework
- jQuery
- JavaScript
- Dropbox API
- PayPal Development
- Visual Basic
- YouTube Development
- Google Maps API
- Google Places API
- SAP Crystal Reports
- Facebook Development
- Transact-SQL
Groups: AspDotNetStorefront, Microsoft Certified Professionals
Mobile Application Developer
India - Last active: 13 days ago - Tests: 1
Since last 3 years, I have been developing excellent mobile applications on Android for various clients. I have knowledge about core php and database architecture as well. I am passionate about IT field.I have experience with implementation of following concepts, -In-app purchase -PayPal integration -Instant Push notification (Google Cloud Messaging) -APK Decompilation (Reverse Engineering) -Google GDATA API -Google OAuth 2.0 -Google Maps API -Google Plus API -Facebook,Twitter Authentication & Sharing -AdMob integration -JSON/XML data parsing -Download/Upload data to server (video,images,texts) -Multi-threading and Background services I strongly believe in following the standard practices in development of application to provide quality work with timely completion. I assure you the best service with commitment of excellence.


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Welcome to Independent Living
The place for impartial information about products and services to help with mobility and independence.
Whoever you are – OT, physio or other health professional, family carer, individual with a disability, Independent Living can provide the advice you need. Keep up-to-date with the latest information by subscribing for our free weekly newsletter. You can read the latest issue online here, and sign up for your own copy here.
If you are looking for products, the drop-down menu above will take you to a full range of aids to daily living, mobility and independence, grouped together in categories. Products for professional users, such as care home furniture, hoists, postural and pressure management systems, are similarly grouped. Just follow the links under "Independent Living" or "Care Professional"
News Centre
The Independent Living newscentre, also linked from the menu above, includes case studies, new product focus, industry news, podcasts, guest blogs, and our newsletter archives. For advice on various aspects of living with a disability or caring for someone who cannot live independently, including information on benefits; legislation; keeping warm and well; fall prevention; and generally coping with being a carer, the Advice Centre is the place to look.
Independent Living Newsletter
Our weekly newsletter highlights the latest developments of interest to health and social care professionals, family carers and disabled individuals, including new products and services, changes in legislation, etc. You can read the current and archived issues online here, and sign up to receive your own copy by email here
What's New
- June 23 rd Adass: Care budget cuts 1 comment
- June 9 th Carers Week 2015 1 comment
- June 2 nd Polling stations still not accessible 2 comments
- May 26 th Bedroom Tax Update Leave a comment
- May 12 th Should Charity Chiefs Be Paid? Leave a comment
- April 28 th Care Act Principles in Action? Leave a comment
- April 21 st The Care Act – what's changed? 1 comment
- April 13 th Insurance for Mobility Scooters? Leave a comment
- March 24 th Better Care Fund – what's coming Leave a comment
- March 23 rd Cut and Shut Stairlifts Scam Leave a comment
- February 17 th Mobility Scooter Safety – training required? 1 comment
- February 11 th Fear of Dementia trumps Cancer Leave a comment
- January 21 st DLA to PIP, some numbers Leave a comment
- December 29 th Shropshire Council castigated by Ombudsman 1 comment
- December 1 st The Essential Carers Guide To Dementia 3 comments
- November 12 th Access – or the lack of it Leave a comment
- October 14 th Mobility Scooters: Legally Not Vehicles 4 comments
- October 7 th Disabled Access Tube Map Leave a comment
- September 30 th Great British Bucket List! 2 comments
- September 16 th Blue Badges: Where to draw the line? 7 comments


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(All open air activities are subject to weather conditions)
Our class is designed for all levels, and If practiced with consistency, improves flexibility, builds strength and develops control and endurance in the whole human body.
Activity time: 45 minutesMeeting point: The SPAMaximum number of participants: 4 personsNo charge
The ultimate workout. The 1.700 steps to the village of Nocelle, take you step by step through carpets of wildflowers and up to one of the most spectacular views of the Amalfi coast. Trainers or trekking shoes necessary. (If you have a heart condition, we recommend you to abstain from this activity).
Activity time: 2 hours Meeting point: The SPAMaximum number of participants: 10 personsNo charge
We will take you to Praiano where the owner of the factory "Il Gusto della Costa" will introduce you to the world of the Amalfi coast lemons followed by the degustation of their products.
Activity time: about 2 hours Meeting point: Hall on the 5th floorMaximum number of participants: 8 personsNo charge
Join our Maitre d'Hotel who be delighted to introduce you to a selection of the finest cheese made in Italy and in particular in Campania.
Activity time: 1 hour Meeting point: La Sponda restaurant on the 3rd floorMaximum number of participants: 8 personsCost: 20 Euro per person


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ADAMS, Glenn, North Charleston
BEARD, Lewis Jr., Mount Pleasant
BLACK, Sam, North Charleston
BOWMAN, Pernell, Eutawville
CANTEY, Sandra, Simpsonville
CHAVIS, Audrey III, Johns Island
COKER, Maureen, Cross
DANSBY, Geneva, Charleston
DAVIS, Diane, Summerville
FERSNER, Martha, Orangeburg
FITZPATRICK, John, Beaufort
FUTERAL, Irvin, Mount Pleasant
GETHERS, Rachel, Charleston
GLENCAMP, Rebecca, New York
GOFF, Richard, Williams
GREENLEE, Joseph, Indiana
HORLBACK, Moses Jr., Mount Pleasant
JOHNSON, Augustine, Summerville
JORDAN, Robert, St. Helena Island
LIVINGSTON, Dorothy, St. George
MASCARO, Albert Jr., Beaufort
MELTON, Margaret, Goose Creek
OPOULOS, Grant, Summerville
RATCLIFFE, Ronald, New Jersey
RAY, Timothy, Summerville
SESSOMS, Sandra, Summerville
STRICKLAND, Randall, Summerville
STUKES, Floyd Jr., Goose Creek
WESTBROOK, Suzanne, Johns Island
WOODY, Darlene, Oklahoma
- Keywords
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Amherst Comes up Short Against Wesleyan, 6-5
Chris Fitzpatrick anchored the Amherst defense with
a team-high five ground balls against Wesleyan.
Amherst seemingly did everything it needed to pull out a win this afternoon, out-shooting Wesleyan 34-20, winning the ground ball battle 36-31, and going 2-for-4 on man-up opportunities. The Cardinals won 11-of-15 face-offs to control the possession game, and also got 12 big saves from senior Mike Borrero to hold on for the win.
Wesleyan scored the day's first goal with 11:22 to play in the first quarter, as Russ Follansbee netted an unassisted goal past Amherst quad-captain Matt Pietroforte (Brooklyn, NY). Amherst responded with a three-goal run, including back-to-back scores from J.T. Milone (Manhasset, NY). Milone's goals came a little over five minutes apart, with the second one coming on a man-up assist from Alex Fox (Garden City, NY). Amherst's lead grew to 3-1 with 2:27 to play in the first, as senior Brett Miller (Wantagh, NY) assisted junior Tom McDonnell (Manhasset, NY).
The Cardinals battled back with a strong second quarter, scoring the only two goals of the frame early on. Lonny Blumenthal and Follansbee put home the pair of Wesleyan scores with 13:50 and 12:18 to play in the stanza. The duo of unassisted scores tied the game 3-3 heading into halftime.
Wesleyan regained the lead for on a Jon Killeen goal early in the third quarter, as the Cardinal junior finished off a feed from senior Adam Kirk. Just 1:31 later, McDonnell responded for Amherst with the Lord Jeffs' second man-up goal of the game, this time on an assist from Luke Arnold (Lincoln, MA).
The Cardinals' John Froats and Amherst's McDonnell traded even strength goals through the middle of the third quarter, keeping the game deadlocked at 5-5. Killeen put Wesleyan on top 6-5 with 1:52 on Kirk's second assist, providing what would ultimately stand as the game-winner.
The fourth quarter finished scoreless on both sides of this long-standing rivalry, but was not without excitement. Wesleyan's Nate Green was called for a pushing penalty with just 51 seconds to play, giving Amherst a golden opportunity for an equalizer. The Lord Jeffs put heavy pressure on Borrero, who made a trio of big saves in the fourth quarter, with none bigger than a point-blank save on a Milone bid with 17 seconds to play.
Amherst got strong performances in the defensive end of the field, holding Wesleyan well below their 10.58 goals-per-game season average. Senior quad-captain Chris Fitzpatrick (Fort Salonga, NY) and classmate Nick Gilligan (The Woodlands, TX) each had stellar games. Fitzpatrick scooped up a team-high five ground balls, while Gilligan drew a pair of penalties while pushing Amherst's transition game.
The Lord Jeffs will have just a few days to recover from this hard-fought decision before hosting Springfield College on Wednesday evening at 7 p.m.


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Results 1 to 5 of 5
August 20th, 2007 #1
Alan Watts meets Matt Stone and Trey Parker
Alan Watts, one of the great guys of modern times, set to the animation of Matt Stone and Trey Parker. I love Watts, even if he can be a little crazy
For more watts check out:
http://www.alanwattspodcast.comCave House Studios - creative animation and video
What the Sketchbook
Hide this ad by registering as a memberAugust 21st, 2007 #2
Wow! Super strange, I've been thinking about this subject the whole morning. The animation was very funny, especially the visualisation of coaxing.
gadammit it's
The Selenium Six
..seer..alzorath..bunny..max xiantu..liquidjack..beershite..
August 21st, 2007 #3
August 21st, 2007 #4
August 21st, 2007 #5
Awesome link thanks Insect666!
Cave House Studios - creative animation and video
What the Sketchbook


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A Guide to the Secret Heart of Asian Martial Arts
Pressure-point Fighting
A Guide to the Secret Heart of Asian Martial Arts
Pressure-point fighting—the practice of manipulating the body's vital nerve and reflex points for self-defense—offers the unique ability to neutralize attackers without causing any permanent harm. This intricate and temporarily devastating self-defense system has obvious advantages. What it hasn't had is a comprehensive guidebook from the Western perspective. Now martial arts expert Rick Clark offers all the fundamental pressure-point techniques—illustrated with hundreds of photographs and twenty-five detailed pressure-point charts—melding the ancient Asian knowledge with modern Western medicine and science.
Here, at last, contemporary readers can learn to utilize this effective, reliable defensive art on their own terms. With simple step-by-step instructions for how and when to use pressure point fighting to your best advantage, Pressure-Point Fighting: A Guide to the Secret Heart of Asian Martial Arts includes: Core Principles; The Paradigms: Modern and Traditional Chinese Medicine; Analysis; Kata Applications; and The Points.
- Tuttle Publishing |
- 208 pages |
- April 2000


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The Good Wife
Matt Czuchry Talks About 'The Good Wife' Ahead Of Season Finale
In the Season 6 finale of "The Good Wife" on Sunday night, Alicia Florrick, played by Julianna Margulies, faces an uncertain professional future.
'Birdman' Tops Golden Globes With 7 Nominations; Showtime Dominates TV Nods
"Birdman" squawked loudest in the Golden Globes nominations, flying away with a leading seven nods including best picture in the comedy or musical category. Showtime dominated the television nominations with nine.
'Two And A Half Men' Comes To An End While New Shows Premiere
CBS announced today that 'Two and a Half Men', one of television's most successful comedies, will end its 12th and final season with a special one-hour series finale.
Report: Archie Panjabi Leaving 'The Good Wife'
Emmy Award-winning actress Archie Panjabi will be leaving the CBS hit drama after six seasons.
David Hyde Pierce Joins 'The Good Wife'
CBS announced this week that David Hyde Pierce, who many will remember for his award-winning role in the TV series "Frasier," will be joining the cast of "The Good Wife" this season.
Billy Crystal's Somber Tribute To Robin Williams Among Emmy Highlights
The 66th Annual Emmy Awards ceremony took a somber turn as Robin Williams was remembered with restraint and grace by his longtime friend, Billy Crystal.
Westchester County Now On A-List Of Hollywood's Sought-After Shooting Locations
Some really big movies have been filmed in Westchester over the last several years. Now, the county film office hopes to cash in on small-screen productions and lure more television shows to town.
Several CBS Actors To Receive 'Walk Of Fame' Stars
Several actors from hit CBS shows are slated to receive stars on the Hollywood Walk of Fame next year.
"Big Bang Theory" and "The Good Wife" Lead Critics' Choice Awards With 5 Nominations Each
CBS' "The Big Bang Theory" and "The Good Wife" have received the most nods for the fourth annual Critics Choice Television Awards, tying with many cable networks' offerings.
Spoiler Alert: Josh Charles Explains Exit From 'The Good Wife'
Sunday's episode of the show "The Good Wife" featured an unexpected twist that has fans of the series reacting deeply.
CBS Announces Renewals Of 18 Primetime Shows Next Season
Combined with two previously announced renewals, the network has now picked up 20 returning series for 2014-2015.
Mayor de Blasio To Appear On 'The Good Wife'
Mayor Bill de Blasio will be making a guest appearance as himself on an episode of "The Good Wife" next month.
New Bruce Springsteen Songs Featured On 'The Good Wife'
This weekend, fans will be able to hear Bruce's entire album. Following this Sunday's episode of The Good Wife, the album will be available for streaming exclusively at CBS.com.
Cast And Crew Of 'The Good Wife' Take Time To Help Sandy Victims
To celebrate the upcoming hundredth episode of the CBS smash hit The Good Wife, Julianna Margulies, co-stars Chris Noth, Josh Charles, and the entire cast and crew got together to help rebuild six homes in the Rockaways.
Chris Noth Talks Acting, Drama & His Commitment To Hunger Relief
Noth has starred as Peter Florrick on the hit CBS drama for four seasons — but when he's not juggling family and politicall issues on the show, he's keeping busy off screen with charity work.


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Home > Conferences & Events > Conference Details
FMCAD is the twelfth in a series of international conferences on the theory and applications of formal methods in hardware and system verification.
22 Oct - 25 Oct 2012
Microsoft Research Cambridge
Cambridge, United Kingdom
Gianpiero Cabodi
Dipartimento di Automatica e Informatica
Politecnico di Torino
Corso Duca degli Abruzzi 24
Torino Italy 10129
Please see the conference Web site for full details.
Abstract submission deadline: 09 May 2012
Final submission deadline: 20 May 2012
Notification of acceptance date: 13 Jul 2012


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September 26, 2013
The campaign created buzz by leveraging the Yahoo Mobile homepage that simulated a demonic possession of a user's phone. Upon landing on the homepage of Yahoo Mobile, users' mobile devices started an automatic search, typing "All the activity has led to this." Users were then pushed to a search page where 'Paranormal Activity 4' was featured. Following that, users received an "incoming video call" alert from the film's teenage character. If the user clicked "Accept," they were redirected to a chilling, frantic video call and sent back to the film's homepage. This auto-initiated execution garnered over five million impressions, and interaction rates exceed industry standards by almost 200 percent.
'Paranormal Activity 4' has also received two nominations for the DigiDay Mobi Awards in the Best Mobile Branding Campaign category for work in the US and UK. Winners will be announced on October 9th.
The IAB MIXX Awards elevate interactive advertising by celebrating the world's most creative and high-impact digital executions. http://www.iab.net/mixxawards/gallery2013/
The first annual Mobile Mafia Awards recognizes brands, agencies and media tech companies that are setting new standards of marketing excellence in the mobile advertising world.


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Witton Albion chairman Mark Harris.
Exclusive by Andrew Simpson, Senior Sports Writer / / SportFollow @simmo_on_sport
MARK Harris believes the decision by a newly-formed football club to play its home games in Winsford, and not in Northwich, represents an opportunity missed.
Witton Albion's chairman told the Guardian that a deal had been close to share the pitch at Wincham Park with 1874 Northwich, who will host opponents out of town instead.
They will stay initially for two years at Barton Stadium
"I'm disappointed, because to me it makes total sense for the two teams to play out of one stadium if we're serious about engaging with the community around us," he said.
"The door is not shut, but we respect the decision that has been made."
When invited to, 1874 chairman Paul Stockton declined to share – at least for now – the reasons why an agreement could not be reached.
His opposite number was less reticent.
Harris said: "A deal like this one has to meet certain commercial requirements on both sides. In short, it costs more to run a place like Wincham Park than it does a ground with a lower grading.
"We had a bottom line, the question was always going to be whether the new club were prepared to reach that.
"I must stress we have not been in any way greedy in terms of the amount of money we were seeking; in our view, it was a reasonable sum.
"Of course sharing our pitch would have been a bonus in terms of additional income, but I applaud the financial prudence the supporters trust shown.
"They conducted themselves in a professional way from the moment they first made contact.
"In their shoes, I might have reached the same conclusion."
He said that 1874 Northwich's choice, confirmed to members at a Special General Meeting last night, Tuesday, does not necessarily give Witton an advantage.
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Not in economic terms anyway.
He added: "At the end of the day, the new club will be playing at least three divisions below us so present no immediate threat on the pitch.
"Ever since Northwich Victoria moved away from the town, it's not suddenly opened more revenue streams for Witton Albion.
"Local companies do not have the same discretionary spend anymore in terms of sponsorship, so our challenge is to be attractive in other ways.
"We're ambitious, and have plans to improve our facilities to demonstrate our worth to the local community.
"I believe engagement with people around us that is key to our future, and that of non-league football."
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Comments (2)Please login to enable comment sorting
Witton Albion chairman Mark Harris says a chance has been missed as 1874 Northwich chooses to play in Winsford
"They conducted themselves in a professional way from the moment they first made contact."
Within the local football scene, after recent experiences, what a pleasure to be hear the word 'professional' linked to the name Northwich again.
Within the local football scene, after recent experiences, what a pleasure to be hear the word 'professional' linked to the name Northwich again.
With Mark Harris at the helm, you can always rely on Witton Albion to act in a Professional manor. Mark is very well respected in Footall, like another respected Wittoner, the late Tom Stelfox.
Never say Never.
Never say Never.


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160 People's Plaza, Newark, DE, 19702, US
We are located in the Peoples Plaza Shopping Center in Newark, DE 19702. Next to the Rt.40 & Rt. 896 intersection.
We are also a Shining Star Club representing the Best of Curves in the U.S. and approved by Curves International! Also Cleveland Clinic Certified Approved Coaches.
Peoples Plaza - Phone (302) 834-8004 Newark, DE 19702
We are here for one reason only. To get you results and improve your health while having fun and surrounding yourself with positive people.


text:
Officials in Virginia are bracing for the impact of the federal budget cuts that start trickling down. Lawmakers in the commonwealth disagree about what should be done with the sequestration.
So now they're dealing with the fallout: cuts to education, housing, healthcare, conservation programs – the list is seemingly endless. Virginia Democratic Senator Tim Kaine says many federal workers and contractors in the commonwealth will feel those cuts directly.
President Obama was in Newport News, Virginia today highlighting the impact of pending budget cuts on the state's defense industry. Virginia Republicans are glad the president is highlighting the state's robust defense industry. But Virginia Congressman Randy Forbes says the president's time would have been better spent in Washington negotiating with congressional leaders.


text:
Rambo Iii
Watch Movies Online
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On top of Watch Movies Online, you can also watch your favorite TV-Shows online by browsing our partner websites listed under the TV-Show section of 10StarMovies?
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Watch Rambo Iii Online
Release:May 25, 1988
RunTime:1 hr 41 min
IMDB Rating:5.6/10 (66885 votes)
Director:Peter MacDonaldActors:Sylvester Stallone, Richard Crenna, Marc de Jonge, Kurtwood Smith, Spiros Focás(View All)
Description: Watch Rambo Iii full movie online for free directed by Peter MacDonald produced in 1988. Genres are Action, Adventure, Drama, Thriller.
Fatal error: Allowed memory size of 33554432 bytes exhausted (tried to allocate 13405255 bytes) in /home/star10/public_html/cache-credits/Rambo_III_1988.php on line 1


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Originally written on Fox Sports | Last updated 12/26/12
The San Diego Chargers say they have sold enough tickets to lift the local blackout for Sunday's season-finale against the rival Oakland Raiders. The sellout snaps a string of three straight blackouts for the Chargers, who will miss the playoffs for the third straight season. Overall, the Chargers had four games blacked out this year. The sellout is likely due to interest by Raiders fans in seeing their team's only Southern California appearance of the season. San Diego is 6-9 and the Raiders are 4-11. San Diego is expected to fire coach Norv Turner and likely general manager A.J. Smith. --- Online: http://pro32.ap.org/poll and http://twitter.com/AP-NFL
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NR; 1:40 running time
War, by its very nature, doesn't give you weekends or nights off. So it is in"Declaration of War,"a vibrant and heartfelt French film that captures the mood and the memories of young parents who found themselves in the trenches fighting for the life of their child. Read the full "Declaration of War" movie review
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The Oil Garden Aromatherapy Thyme
Thymus vulgaris herb
Emotional Wellbeing
Thyme has a powerful, penetrating warm spicy and herbal aroma. Thyme is stimulating, energising and provides encouragement.
Physical Wellbeing
The Oil Garden Aromatherapy Thyme Ingredients
Adult: For the relief of symptoms of colds and flu and the temporary relief of bronchial cough and sore throat: add 5 drops to 1L steaming water, cover head and inhale vapour. For relief of muscular cramps and spasms: add 3 drops to 10mL base oil and massage onto affected area. Adults only.
Avoid in cases of high blood pressure, epilepsy and pregnancy. If symptoms persist seek the advice of a health care professional.


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Results 1 to 2 of 2
Thread: BBqlab, seeking help
January 8th, 2011 #1Registered User
- Join Date
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- Italy
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BBqlab, seeking help
Hi ConceptArt
Now, here's the fact: me and a bunch of my friends are currently working on the development of a game for the final exam that we will hopefully have in three years.
We have almost everything: game designer (me), 3d developer, ''story men'', ecc.. but we lack in something fundamental, the artwork maker.
So here am I, seeking the man
If anyone is interested, write a PM or write directly below here!
Cheers, BBQlab
P.S: yes, BBQlab is the name of our ''software house''
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Hide this ad by registering as a memberJanuary 8th, 2011 #2The Penvirates:: Xeon_OND :: PermaN00b:: Kamber Parrk :: Cygear ::Diarum
"Life itself is your teacher, and you are in a state of constant learning." -Bruce Lee


text:
Revlon Colorburst Lip Butter - Pink Truffle
243 reviews
82% would repurchase
Package Quality: 3.9
Price: $$
Package Quality: 3.9
Price: $$
on 11/10/2012 7:11:00 AM
Age: 19-24
Skin: Acne-prone, Fair-Medium, Warm
Hair: Brown, Straight, Medium
Eyes: Brown
Another favorite lip butter! A perfect pink nude lip color for me that's perfect for the fall/winter season. I was afraid this would turn up more brown/mauve but there is a hint of pink. It's moisturizing and is pretty pigmented.
on 10/29/2012 12:52:00 AM
Age: 44-55
Skin: Combination, Other, Not Sure
Hair: Red, Other, Other
Eyes: Hazel
Dry, dry, dry! I LOVE the shade, but the texture is so dry it needs a lip balm underneath or a clear gloss on top, which makes the staying power non-existent. I much prefer Clinique's Butter Shine lipsticks for texture, but have a problem with staying power there as well since they're SO moisturizing. I guess I should just avoid any lip product with "butter' in the name. *sigh*
on 10/15/2012 6:55:00 AM
Age: 44-55
Skin: Dry, Medium, Warm
Hair: Other, Wavy, Coarse
Eyes: Hazel
I've never tried lip butter before so my review score is based on lip butters. As I've matured I've realized the lipsticks I used to wear don't suit me anymore. With the consideration that my upper lip line is fading, darker shades just don't work so I decided to change to natural lighter colours & this was my first attempt. This colour is unusually beautiful. It's a muted pinky light mauve & would go with anything. I absolutely love the subtly of this colour. The reason I wouldn't repurchase is due to its lack of staying power yet it never claimed to have this. I think my next purchase would be a lighter more natural lipstick with the staying power or a pretty lip-gloss that can be applied quickly yet won't show over my lip line. For lip butter, I think this colour is very pretty & would recommend it if you like lip butters.
on 9/30/2012 9:29:00 AM
Age: 19-24
Skin: Normal, Fair, Warm
Hair: Black, Straight, Medium
Eyes: Black
This is the first lip butter I bought but after buying all the other colors this gem was slowly pushed aside. Now that fall's here, I was rummaging through my makeup drawer and saw this. It is a gorgeous brownish pink color, a mylbb shade that doesn't have any shimmers in it. It goes on sheer on one swipe but can easily be built to a good pigmented color. This doesn't stay on and don't be fooled with the name because it won't really give as much moisture as other lips butters or tinted lip balms out there. It is pretty easy to apply and has a faint sugar-y dessert small. Perfect to pop in your bag for quick touch ups.
on 9/30/2012 8:12:00 AM
Age: 36-43
Skin: Combination, Fair, Cool
Hair: Brunette, Other, Other
Eyes: Blue
UPDATE: All my Balm Stains and Lip Butters are getting tossed, as they cause tiny pimples/blackheads on my lipline. Invariably by the end of the day when I wear these. Bizarre, and no thank you!
On me (very fair, pigmented lips) this is a warm, medium pink. Since it's sheer, it's very "neutral" in that it could go with any look. I actually find the formula feels quite moisturizing! Not as much as a treatment balm, but it certainly doesn't actively dry my lips, and is much more moist and smooth than most lipsticks.
Tip: If you find this shade too warm-toned, try the Revlon Just Bitten Balm in Honey. I bought both at the same time and they are all but identical; the Just Bitten has a cooler undertone but they are exactly the same depth of shade and level of coverage.
on 9/27/2012 10:13:00 PM
Age: 30-35
Skin: Normal, Olive, Warm
Hair: Brunette, Other, Other
Eyes: Green
Meh. Milky pink on me. I would imagine it would look nicer on fairer skintones, but tanned ladies or anyone over NC30 should go a bit darker. The formula isn't as great as it was hyped to be.
on 9/27/2012 10:04:00 PM
Age: 25-29
Skin: Normal, Fair-Medium, Warm
Hair: Black, Wavy, Medium
Eyes: Brown
I'm loving this lippie for everyday use. On me its a warm rosy nude color. My lips are lightly pigmented and this is my lips but a bit deeper. I love that this is not glittery and goes on so smoothly.
on 9/26/2012 7:08:00 AM
Age: 19-24
Skin: Combination, Fair, Cool
Hair: Brunette, Wavy, Fine
Eyes: Green
After reading and hearing about how great these things are I thought what the heck and I picked one up from my local drug store. I chose this color because I liked the name and it looked pretty. I like the color I do not find them that moisturizing over all and I hate the taste I was a fan of this up until I got a taste ugh it put me off wearing it now whenever i go to reach for this I remember the taste and I pass over it really is a shame to.
on 9/21/2012 4:43:00 PM
Age: 30-35
Skin: Combination, Fair-Medium, Not Sure
Hair: Brunette, Other, Other
Eyes: Brown
So, after all the wonderful reviews, I ran out and got this. I am a total lip junkie and really do not need any more lip products, but could not wait to try a new one. :) So, on my NW15-NW20, this looks too dark pink. I was hoping for a more neutral color, but you can REALLY see this on my lips. Slightly disappointed for that. Now, I would purchase any of the other lip butters. This was my first and I loved how creamy and glossy it is, and even after the product was off my lips, it gave them a slight tint. It is really nice...
on 9/19/2012 9:17:00 AM
Age: 25-29
Skin: Combination, Other, Not Sure
Hair: Red, Other, Other
Eyes: Green
I can't believe I haven't reviewed this product yet. And how fitting that it would be my 100th review because WOW!! I'm in love with it! It was my first Lip Butter, and I've almost completely used it up despite the hundreds of barely, used, half used, and brand new lippies I have in my collection. It's rare that something like this happens. It's the perfect shade to just throw on to tie everything together. It goes with damn near every eye look. And today? I forgot to wear blush, and I found this in the bottom of my purse. Hello, perfect cream blush shade!! Will definitely be repurchasing.
Popular Lipsticks


text:
User Reviews & Ratings - Bactroban Top
Read user comments about the side effects, benefits, and effectiveness of Bactroban Top.
Overall User Ratings53 Total User Reviews
User Reviews
Learn about
User Reviews
Reviewer: 35-44 Male on Treatment for 2 to less than 5 years (Patient)
Ease of Use
My father and I experience some kind of foot fungas. He said his Doctor said is was in our bodies and would never go away. However, this ointment within days makes my skin like that of a baby! Amazing results! Typically every two to three weeks I give myself a small treatment where needed. So either the fungas is not strong or the medicine is just great. I would defintely recommend it for that kin ... Show Full Comment
Reviewer: wibrowns, 55-64 Male on Treatment for less than 1 month (Patient)
Ease of Use
I first used this product to treat an open wound after surgery. I worked great!! I use oxygen and occassionally get raw skin on my nose or ears from the canula. This clears it up in just a few days. Wonderful product.
Reviewer: ozzie504, 45-54 Female on Treatment for less than 1 month (Patient)
Ease of Use
Reviewer: TErry, 45-54 Male on Treatment for less than 1 month (Patient)
Ease of Use
I have a cut behind my ear and it was infected,in two weeks it was gone.
found this review helpful.
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Reviewer: bactroban, 65-74 Male
Ease of Use
can you use this on shingles
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Undercroft Lyrics
(1-62 of 62 song lyrics)
Selected popular Undercroft song of Friday, July 3 2015 is "They Kill For Me".
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Ruins of Gomorrah
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You Are Blind lyrics
To The Final Battle lyrics
Through The Night's Veil lyrics
They Kill For Me lyrics
The Failure Of The Creation lyrics
The Cartomancer lyrics
Temples Of Carrion lyrics
Sub Race lyrics
Spectral Town lyrics
Son Of Darkness lyrics
Sodom & Gomorra lyrics
Scream Of Immortality lyrics
Sabatical Potion lyrics
Rumanian Impaler lyrics
Under The Broken Sign lyrics
Wake Up From Your Dreams lyrics
Whispers From Other Sky lyrics
Ruins Of Gomorrah lyrics
Spit At Them lyrics
Bleed Me lyrics
My Former Glory lyrics
Enemigo lyrics
Black Magik Witches lyrics
Lies Within lyrics
Dead Human Flesh lyrics
Demonized lyrics
Bury My Burden lyrics
At The Gardens Of Hatred lyrics
Shadows lyrics
Unfit Earth lyrics
Road To Desolation lyrics
Psychopath lyrics
Empire Of Orgies lyrics
Demons Awake lyrics
Dementia lyrics
Dark Water's Captive lyrics
Danza Macabra lyrics
Celebration Of Sin lyrics
Carros De Fuego lyrics
Bridges To Melissa lyrics
Bonebreaker lyrics
Bleed To Death lyrics
Blackening The Sun lyrics
Belfry Of Sorrow lyrics
Behind The Cassock lyrics
Evil Being lyrics
Evilusion lyrics
Fake Messiah lyrics
Perverse Praise lyrics
Oppressor lyrics
Open Your Eyes To The Pain lyrics
Mercy lyrics
Maniakiller lyrics
Lords Of Terror lyrics
Law Of Sacrifice lyrics
Lapidation lyrics
Insane Outcry lyrics
In Join With The Devil lyrics
I'm Prepared To Die lyrics
I Demand Revenge lyrics
I Condemn lyrics
Beheading False Prophets lyrics
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Related Information for Undercroft
is one of the most important Death Metal bands of Chile. The beginning of
is marked by the appearance of their mythical 2 first demos "To Final The Battle" the pioneer one, appeared in May of 1993. Then came "Demons Awake… Revenge is Near" in November of the same year. That led them to the their debut album, called "Twisted Souls", this one was recorded in 1995...
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