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The Bank: LendingTuesday, 7th July 2015 21:00 - BBC TwoThe final episode of The Bank explore our need to borrow more money to buy anything from mortgages to plastic surgery. Read more: The Bank: Lending
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Challenging ideas in mental health
Take a new and different look at mental health. This unit invites you to think...
Take a new and different look at mental health. This unit invites you to think differently about life's dilemmas by taking account of the views of all concerned, especially people experiencing mental distress. It explores ideas and practice in mental health, and will appeal to a wide range of people.
By the end of this unit you should be able to understand:
- the complexity and dilemmas of diverse perspectives in the field of mental health and distress;
- the importance of service users'/survivors' experiences and perspectives;
- how mental health issues affect everyone;
- the range of risks faced by service users'/survivors' in their everyday lives.
- Duration 18 hours
- Updated Thursday 13th March 2014
- Intermediate level
- Posted under Health
- Current section: Introduction
- Learning outcomes
- 1 Extract 1: Boundaries of explanation
- 2 Extract 2: Whose risk is it anyway?
- 3 Extract 3: The business of madness
- References
- Acknowledgements
Study this free course
Enrol to access the full course, get recognition for the skills you learn, track your progress and on completion gain a statement of participation to demonstrate your learning to others. Make your learning visible!
Challenging ideas in mental health
This unit takes you on a journey of discovery where you are invited to challenge ideas, both new and old, in relation to mental health. It is made up of a series of three extracts. The first extract, 'Boundaries of explanation', sets out the theme of boundaries: boundaries within and between groups; within and between explanatory frameworks; and within and between experiences of mental health and distress. The second extract, 'Whose risk is it anyway?', considers a critical account of the increasing focus on risk (particularly risk to others) in policies and professional practice since the 1980s. The third extract, 'The business of madness', looks at two controversial areas of mental health: the growth of mental health as a business, driven in part by market forces, and the profit motive.
This free course is an adapted extract relevant to The Open University course K272 Challenging ideas in mental health, which is no longer taught by the University. If you want to study formally with us, you may wish to explore other courses we offer in this subject area [Tip: hold Ctrl and click a link to open it in a new tab. (Hide tip)] .
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Publication details
Originally published: Friday, 20th May 2011
Last updated on: Thursday, 13th March 2014
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Products/Services for Composite Worktop
Furniture - (819 companies)...a table with a drawer or shelf underneath. Tables are furniture made from wood, aluminum, and stainless steel. Despite the base material, the top may be covered in composite wood, a laminate, steel, or a rounded-edge maple top. Cabinets. Office... Learn More
Composites and Composite Materials - (266 companies)Composites and composite materials typically consist of a matrix and a dispersed, fibrous or continuous second phase. The second phase may reinforce the material, alter electrical or magnetic properties, or enhance wear or erosion resistance... Learn More
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Composite Technology environmental advantages over traditional thermosets due to its recyclability and emitting no or low VOCs. Crown Plastics applies its proven expertise in continuous sheet manufacturing to thermoplastic composite technology. We offer the following capabilities: • Continuous belt press (unlimited lengths*). * Dependent upon composite components. • 700 º F temperature capability. • 30 ″ width (with 48 ″ expandability). • Up to .125 ″ thick cross sectional molding... (read more)Browse Polymer and Plastic Composites Datasheets for Crown Plastics Co., Inc.
Novaflex Group
Pumpflex Composite Hose Novaflex Pump-Flex Composite Hose is specifically designed for the Pump Rental Industry. This suction & discharge hose provides extreme flexibility, light-weight handling and excellent service life. Excellent for the transfer of water, dirty oily water, and light chemicals. (Consult Novaflex Chemical resistance chart for chemical compatibility before use). Advantages: Crimped couplings absorbs pump pulsations. Less manpower to install than rubber hose. Easy to package for shipping &... (read more)Browse Industrial Hose Datasheets for Novaflex Group
ESDU Composite Series Solutions to strength analysis problems which are met in the design of fibre-reinforced laminated composite structures. Validated Methods and Software. The ESDU Composite series provide a collection of data for use in the design of fibre-reinforced laminated composite materials. The information provided is primarily for use in aerospace, but has wide application to other areas of engineering where composite materials offer benefits. The information is accepted by the Federal Aviation... (read more)Browse Standards and Technical Documents Datasheets for IHS ESDU
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KDP Composite Plates Lapmaster series KDP Composite Plates for Diamond Lapping and Polishing. Materials available include Iron (primary lapping/roughing), Copper (all-around lap or polish processing), Ceramic (intermediate lap or polish with reduced staining, corrosion and conductivity attributes), Tin-Lead (finish polish) or XP (finish polish). Available in standard diameters of 12" to 36", although custom sizes (smaller and larger) and shapes available. Can be configured in most standard groove patterns including... (read more)
Osborne Industries, Inc.
Metal Fabricating for Composite Parts Osborne Industries is an OEM supplier of thermoset plastic parts utilizing Reaction Injection Molding (RIM) and Resin Transfer Molding (RTM) processes. To support its plastic composite molding, Osborne Industries has a large metal fabrication department that can perform secondary operations. The metal fabrication department contains a large variety of presses with the capability to bend, punch and shear all types of metal. Osborne Industries also has large metal saws, numerous welding stations... (read more)Browse Composite and Fiberglass Molding Services Datasheets for Osborne Industries, Inc.
Ethernet Extension Experts (Enable-IT, Inc.)
650 Composite Extension Kit Includes the Following. (2) 650 Composite A/V units. (1) 650 A/V Extender Installation Guide. (1) Set of mounting hardware. The Enable-IT ™ 650 Composite A/V Extender is a RG59 coax Video and RCA jack stereo solution that drives your signals up to 657ft or 200m. This A/V extender kit combines both video and audio feeds into a RJ-45 Ethernet jack for transport over any Category rated Ethernet cabling such as CAT5e/CAT6 between the Enable-IT 650 units. Enable-IT 650 A/V Extenders... (read more)
McClean Anderson
Perfect for composite part development. The Little Hornet. Our basic winder, perfect for composite part development. The Little Hornet is McClean Anderson's answer to affordable "use it right out of the box" technology. The Little Hornet features 2-axes of computer controlled motion and is driven by the Windows ® based Flexwind machine control. The system is further enhanced with our Windows ®-based Composite Designer winding pattern development software. The WLH is uniquely matched for both R &D and high production. All... (read more)Browse Filament Winding Machines Datasheets for McClean Anderson
Despatch Industries
Composite Curing Ovens The Despatch S-Series walk-in oven is designed for industrial process versatility, dependability and economical utilization of facility space. These walk-in ovens are typically used for aging, curing, bonding, annealing, drying, baking and heat treating. Despatch's design integrity, manufacturing experience and overall emphasis on quality and innovation ensure your exact requirements will be met. S-Ovens offer customers a variety of beneficial features, including vacuum ports, lift doors, and... (read more)Browse Ovens (industrial) Datasheets for Despatch Industries
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ASCO Composite Solenoid Valves ASCO Introduces Composite Solenoid Valve for Water Purification and Conditioning Applications. FLORHAM PARK, NEW JERSEY, U.S.A., September 27, 2012 – ASCO Numatics, the world 's leading manufacturer of comprehensive fluid automation, flow control, and pneumatics solutions, has introduced the 212 Series of composite solenoid valves that incorporate the new FasNTM universal connection system. The 212 Series has been designed specifically for water purification and conditioning systems... (read more)Browse Solenoid Valves Datasheets for ASCO Valve, Inc.
Daemar Inc.
CJ Composite Bushings traditional metals corrode and fail. You 'll find CJ bearing materials in heavy-duty agricultural, automotive, construction, industrial, marine, railway, and material handling equipment. CJ composites possess a modulus of elasticity that falls between rigid metals and soft plastics. CJ components are rigid enough to support heavy loads, yet compliant enough to tolerate moderate amounts of shaft misalignment without highly stressing the ends. The composite wall acts like a spring and the thicker... (read more)Browse Plain Bearings and Sleeve Bearings Datasheets for Daemar Inc.
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..."b) + c)\n","5.\nex 4203 29 Clothing accessories made of natural or composite leather.\nOf which... ...which only chipboard\nboards without surface finish, boards laminated or\nvarnished for general purposes including worktops .\nFibreboard boards or...
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The coated panels are mostly used for furniture, educational establishment laboratories kitchen cabinets, and worktops , etc. ...analysis is important to determine the adhesive and coating properties of wood and wood-based composite surfaces.
PANOLITE™ is a lightweight composite panel made of two surface board layers and a honeycomb core. ...even more when superposing several panels, allows the creation of distinctive furniture, shelves, worktops and countertops or...

subset: commoncrawl


text:
General Hospital: Season 1, Episode 12,350
Episode #1.12350 (19 Jul. 2011)
TV Episode | TV-PG | | Drama
(awaiting 5 votes)
Reviews: write review
Carly wins custody of Josslyn, but accuses Sonny of going too far in defaming Jax. Lucky and Elizabeth have family night with Cameron and Aiden when Siobhan shows up. Young Molly discusses love with Sam and Jason.
Director:Scott McKinsey
Writers:Michael Conforti (breakdown writer), Robert Guza Jr. (head writer), 1 more credit »
Stars:Steve Burton, Maurice Benard, Ingo Rademacher | See full cast and crew »


text:
Go from jQuery plugin user to jQuery plugin author in a few steps, by turning existing filters or code into reusable, highly configurable plugins.
Create a promotional, animated marquee for the homepage of your WordPress website. The exercise files and code snippets for this course are free to all members.
Find out how to add stylized dropdown menus in Dreamweaver using HTML, CSS, JavaScript.
Find out how to add stylized dropdown menus to your web site using HTML, CSS, and JavaScript.
"You've got my back. When a customer expects me to know something, I know where I can find it fast and get a clear, simple explanation." —Richard R.
more from our members »


text:
Discover a selection of top forums sanji armageddon on the internet. Come to share your passion on forums sanji armageddon and meet other fans of sanji armageddon. Then, why don't you create your own forum of sanji armageddon ?
A Full Metal Alchemist Roleplay site.
fullmetal, alchemist, text-based, roleplay, anime, #armageddon, brotherhood, text, based, forum, fantasy


text:
148Vim mapping
Expand Messages
- Jan 26, 2006No, this is not about the ":map" command. It's about the Vim Frappr!
map. This is where you can find out where Vim users are located in the
world. For some of them you can even see the size of their house
(this depends on the resolution of the satellite image).
Looking at the "Most Members" list you can see that Vim is the 17th
group in the list now. Not bad eh? See the list here:
Wouldn't it be nice to make it into the top ten? Add yourself!
The map is found here: http://www.frappr.com/vim
The Emacs list only has 12 members, that's not what I call
hundred-and-one symptoms of being an internet addict:
171. You invent another person and chat with yourself in empty chat rooms.
/// Bram Moolenaar -- Bram@... -- http://www.Moolenaar.net \\\
/// sponsor Vim, vote for features -- http://www.Vim.org/sponsor/ \\\
\\\ download, build and distribute -- http://www.A-A-P.org ///
\\\ help me help AIDS victims -- http://www.ICCF.nl ///


text:
Welcome to the forum:
Welcome to the iThemes forum. We've created several tutorial video's to help you get you started with using the forum, please check them out!
Also take note of the forum guidelines.
Support hours:
Our moderators actively respond to forum support requests during normal business hours which are Monday-Friday, 8am - 5pm Central Standard Time, typically within one business day. Although some moderators choose to work during the weekends, we can not guarantee immediate attention to your requests. Thanks for understanding.
What is included with support:
Premium support includes theme/plugin issues such as: bugs encountered under normal operation, how to use basic features, basic WordPress help, and basic help with customization (meaning we point you to resources and will help in more depth as time allows). More information.
4th of July weekend:
Please note that due to the 4th of July celebrations, today, Friday July 3 the iThemes offices are closed. Normal Support will resume on Monday July 6.
Thanks for understanding, and have a great weekend.
Query response
Posted 05 February 2010 - 04:51 AM
is it possible to get a response regarding my queries, please, in the past it has always been rapid, so I am not sure whether my AV has been too rigid
Thanks in advance
Posted 05 February 2010 - 04:56 PM
You'll need to address questions and queries to email@example.com
If you have already emailed sales, or used the contact form, please allow at least 24 hours for a response.
Thank you!


text:
South African Miners' Strike Settled
South African platinum miners have returned to work after reaching a pay agreement which ended a five-month-long strike.
South Africa: Platinum Miners Report to Work
South African Press Association, 25 June 2014
Mineworkers at Lonmin, Anglo American Platinum, and Impala Platinum began returning to work on Wednesday following the resolution of the five-month strike in the sector.read more »
South Africa: Markets React to End of Platinum Strike
Voice of America, 23 June 2014
South Africa's AMCU union declared a five-month platinum strike "officially over" on Monday as thousands of miners roared their approval when leader Joseph Mathunjwa asked if they... read more »
South Africa: Platinum Strike Finally Ends
South African Press Association, 23 June 2014
The five-month-long strike in the platinum sector finally ended on Monday with labour union Amcu accepting the employers' offer.read more »
South Africa: Union Submits New Demands to Platinum Miners
South African Press Association, 19 June 2014
Meetings between Anglo American Platinum (Amplats) and the Association of Mineworkers and Construction Union (Amcu) will continue on Thursday.read more »
South Africa: Union Responds to Mining Companies
South African Press Association, 17 June 2014
Trade union Amcu has submitted a response to platinum mining companies over its latest wage offer and it is being analysed.read more »
South Africa: Platinum Workers 'Lost the Most'
Deutsche Welle, 13 June 2014
South African miners and platinum companies were near to an agreement on Friday to end the longest strike in the country's history.read more »
Armoured police patrol near Lonmin's Marikana mine (file photo).
The miners' strike is likely to end after five months of strained negotiations between platinum producers and unions, along with government mediation efforts. Read more »
Negotiations between platinum producers and striking workers have stalled after mining minister Ngoako Ramatlhodi allegedly abandoned mediation efforts. Read more »


text: No recent wiki edits to this page. Return of the Hero, part 2 of 3. A Zero Hour crossover issue. Triumph, a silver age hero trapped in time, has returned looking for the Justice League of America. Unfortunately, the silver age Justice League no longer exists, and Triumph must make do with the remains of a disbanded Justice League International. Elongated Man and the JLI heroes do not believe Triumph's story. Triumph is worried that if he has returned, then the Plasma Men he was trapped with will come back as well. Triumph fights the Leaguers, which prompts the ancient mage Arion to put a stop to them. Triumph and the former Leaguers make their way to Washington D.C., the site of the Plasma Men attack, while Fire finds founding Justice Leaguer Martian Manhunter. Fire finds the Manhunter, who comes to D.C., but who does not remember Triumph. Thinking the whole thing a trick, Manhunter drops Triumph. However, Triumph was right, and the Plasma Men have returned.


text:
Pamela Gardner, 60, memorial service, Friday, Feb. 22, 10 a.m., Bethlehem Lutheran Church, Brush.
Article ID:
Phoenix firefighters pull man out of chimney
PHOENIX (AP) — Phoenix firefighters have rescued a man who became stuck after trying to re-enter a house through the chimney. Full Story
Celebrity birthdays for the week of July 12-18
July 12: Actor-comedian Bill Cosby is 78. Singer Christine McVie of Fleetwood Mac is 72. Actress Denise Nicholas ("In the Heat of the Night") is 71. Full Story
(Photo by Darren Carroll/Getty Images)
Did Tiger Woods cheat with Amanda Dufner?
Lindsey Vonn reportedly caught golfer with his competitor's ex-wife, which is likely why they aren't dating anymore.


text:
Lance Stephenson throws down a monster jam … on a referee (VIDEO)
Feb 2, 2014, 3:30 PM EDT
Lance Stephenson was admittedly mad about not making the All-Star team, and has vowed to "kill everyone in front of him" in order to prove the coaches who left him off the roster wrong.
Apparently, that includes referees.
After a play was whistled dead and the official came onto the floor into the restricted area to make the call, Stephenson didn't stop, and rose up for the monster jam — inadvertently posterizing the referee in the process.
- vikesdynasty - Feb 2, 2014 at 4:01 PM
Every team has an idiot.
- stadix093 - Feb 2, 2014 at 4:03 PM
So does every comment section. You win today.
- ranfan12 - Feb 2, 2014 at 7:54 PM
people have that don't stop when the whistle blows mentality
- vikesdynasty - Feb 2, 2014 at 7:16 PM
Aww you didn't like me making fun of your self entitled drama queen? He's a future jr smith.
- stadix093 - Feb 2, 2014 at 7:21 PM
I actually couldn't care less, I am a Lakers fan. I just didn't see the need for the insult. The guy is having a pretty good season, why the hate? Also we all know you are the only one that gave yourself a thumbs up, get real man. I am sorry, I just saw an easy joke and I took it. Don't get so hurt brotha.
- vikesdynasty - Feb 2, 2014 at 7:46 PM
I'm on my phone app so I have no idea who has a thumbs up or down. I just think the guys need to say I'm going to kill everyone who gets in his way is borderline idiotic. I say it how it is and most done like it but that's not my problem. The best way to get your point across is just play and a lot of these guys open there mouth way too much.
- canadatude - Feb 2, 2014 at 8:36 PM
That's an All Star play !
- antistratfordian - Feb 3, 2014 at 3:33 AM
I would've given the ref the Kemp-on-Lister point. http://stream1.gifsoup.com/view7/2742615/shawn-kemp-dunks-o.gif
- lalifer - Feb 3, 2014 at 3:24 PM
But seriously. Isn't there another pic of Lance Stephenson somewhere around? It seems as if its always this one they show.
Top Posts
- Spurs reset franchise for post Tim Duncan life in one impressive week 12
- Report: Lakers 'actively discussing' trade for Roy Hibbert with Pacers 39
- LaMarcus Aldridge has chosen to sign with Spurs 85
- Who should Clippers get to replace DeAndre Jordan? How about Blake Griffin. 42
- Report: Tobias Harris reaches four-year, $64 million extension to stay with Orlando 25
- Report: Rajon Rondo agrees to one-year, $9.5 million deal with Sacramento Kings 48
- Report: DeAndre Jordan agrees to four-year, $80 million deal to join Dallas Mavericks 58
- Report: Kings signing Marco Belinelli to three-year, $19 million contract 19
- L. Aldridge (6042)
- D. Wade (4341)
- D. Jordan (3643)
- W. Matthews (3530)
- G. Monroe (3232)


text:
Root Catalog
Shop by Brand
6 Items
General Electric / Walmart Style GE-1 Vacuum bags (6pk)$9.99General Electric / Walmart Style GE-1 Vacuum bags are designed to fit all of the GE brand vacuums that require the style GE-1 bags. Learn More
GE UPRIGHT FILTER$17.88This is a GE Upright Bagless Vacuum Cleaner Filter that fits in the dust cup for the 5500 series. Corresponds to GE Filter 61770 Learn More
GE Canister CN-1 Micro Filtration Vacuum Cleaner Bags - 3 in a pack$6.27Micro Filtration vacuum cleaner bags CN1. Fits All Models Using CN-1 vacuum bags such as 6850, 6851, 6852, GE6850, 106766. Learn More
Sandia Raven 10-0197 XP-3 Whisper 6 Quart Microfiltration Vacuum Bag BULK CASE LOT, 50 Pack.$127.50This is BULK CASE LOT purchase of 50 total 6 quart microfiltration vacuum bags for the Sandia 6 quart backpacks. Save BIG off retail price when purchasing bulk. These bags Fit the following Sandia Plastics XP-3 Whisper 6 WERK.20 models; 74-2012, 74-2016, Learn More
Sandia Raven XP-3 Whisper 6 Quart HEPA Filtration Backpack Vacuum Bags, 6 Pk.$25.99These are 6 High quality HEPA filtration vacuum cleaner bags that fit all 6 quart Sandia backpacks. Rather then the standard paper bags which can exhaust microscopic particles, the disposable cloth style of HEPA filtration bag keeps these airborne allerge Learn More
Sandia 6 Series 10-0197 10 Pack Generic Vacuum bags$19.95Sandia 6 Series 10-0197 10 Pack Generic Vacuum bags Better filtration means cleaner air, less dusting, longer secondary filter life, at considerable savings. Learn More
Results 1 - 6 of 6


text:
+Self Employment Opportunities
+Rewarding Salary
+Flexible Hours
On behalf of the State of New Hampshire General Court and the State of New Hampshire Employee Assistance Program, I would like to thank for participating in the Wellness Fair on Friday June 27, 2003. Your contribution to the program was a key element to a successful event benefiting the staff of the general court. Thank ou again...
Located in the bussiest business district area, in the heart of
Manchester, NH
The Massage Clinic
North Eastern Institute of Whole Health
Attention Massage Therapist and Holistic Practitioners!!!
If you chose to work for yourself, you might decide now that you need a space to call your own…
Furnished Massage Clinic with treatment rooms available for rent or lease.
The newly renovated clinic has a reception area, 3 treatment rooms and a private bathroom with shower. Each room is equiped with a massage table and all accessories, ready to use.
With our Competitive rates and Flexible rental options You can… Make your rental choice!
Rent by hour… by half/ whole day… or by weekends…or by any personalized preference…
Rent includes use of furnished treatment room, utilities, wireless Internet, use of reception area and other negotiable options.
Our Massage clinic is a part of one of the largest schools of massage therapy in New England: the North Eastern Institute of Whole Health and is located in the bussiest business district area, right in the heart of Manchester, NH.
For more information about rates, or to schedule a tour, please contact us at
603-512-3444 or by email at
Copyright© 2009 North Eastern Institute of Whole Health22 Bridge StreetManchester, NH 03101(603) 623-5018
Built by NEIWH GROUP


text:
Who Won Our Trip to See Rascal Flatts in Tampa?
Congratulations to Rosanna Sablon! She is the winner of our trip to see Rascal Flatts live at Busch Gardens in Tampa, Florida.
Congratulations to Rosanna Sablon! She is the winner of our trip to see Rascal Flatts live at Busch Gardens in Tampa, Florida.
Florida Georgia Line are one of the biggest acts in country music. Red Rocks one of the most incredible concert venues in the world. We're giving you a chance to experience them both.
The 2014 CMA Music Festival is officially underway, and night two of the country music party was just as sensational as the first. This time, Miranda Lambert, Blake Shelton, and other top-notch country stars thrilled fans with their sets, and a superstar -- the one and only Carrie Underwood -- made a surprise appearance.
Randy Travis stepped out in public -- a rarity since his 2013 stroke -- for his friend Dolly Parton's concert.
Country greats Rascal Flatts are touring again and making a stop in Tampa, FL. We want you to go.
What a hoot, huh? And what a beautiful day for Lubbock's first ever Spring Fest! So glad we brought a camera!
Earlier today Josh Abbott called in and we chatted about the upcoming concert on Saturday at the Lonestar Amphitheater – Spring Fest 2014.
We had a great conversation about the "Lubbock Music Scene" and what it has done for artists such as himself, Pa
Craig Campbell decided to mix things up at WGNA's third Secret Star Acoustic Jam when he sang a country version of pop singer Lorde's "Royals."
George Strait is hanging up his cowboy hat with a final show in Dallas, Texas. If you had a pair of tickets to see the legendary artist, who would you take with you?
Randy Rogers Band is set to headline our first-ever Red Dirt BBQ and Music Festival, on May 3rd, in downtown Tyler, TX. Two weeks before that, on April 15th, their new album "Homemade Tamales" hits stores.
The live album, recorded at Floore's Country Store, features two n
While there are several reasons that I get super excited about warmer weather. Drinks on a patio for happy hour, working in the yard, taking the kids to the park and outdoor concerts!
Mark your calendars for June 1, 2014 for the 16th Annual Wade Bowen Classic in Waco, Texas - Wade's hometown!
Over 200 golfers will come out to participate in the festival style concert and 2-man scramble at $200 per golfer


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Elizabeth Bishop
The Map - Poem by Elizabeth Bishop
Land lies in water; it is shadowed green.
Shadows, or are they shallows, at its edges
showing the line of long sea-weeded ledges
where weeds hang to the simple blue from green.
Or does the land lean down to lift the sea from under,
drawing it unperturbed around itself?
Along the fine tan sandy shelf
is the land tugging at the sea from under?
The shadow of Newfoundland lies flat and still.
Labrador's yellow, where the moony Eskimo
has oiled it. We can stroke these lovely bays,
under a glass as if they were expected to blossom,
or as if to provide a clean cage for invisible fish.
The names of seashore towns run out to sea,
the names of cities cross the neighboring mountains
-the printer here experiencing the same excitement
as when emotion too far exceeds its cause.
These peninsulas take the water between thumb and finger
like women feeling for the smoothness of yard-goods.
Mapped waters are more quiet than the land is,
lending the land their waves' own conformation:
and Norway's hare runs south in agitation,
profiles investigate the sea, where land is.
Are they assigned, or can the countries pick their colors?
-What suits the character or the native waters best.
Topography displays no favorites; North's as near as West.
More delicate than the historians' are the map-makers' colors.
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text:
A system and method for controlling the rate of electroosmotic flow in capillary electrophoresis. A first high voltage power supply is electrically connected to the inlet end of a capillary tube, while a second high voltage power supply is connected at an outlet end. The potential difference across the capillary tube is therefore the difference between the high voltages. Electroosmotic flow can be controlled by varying the two high voltages correspondingly to maintain the same potential difference but to achieve a different voltage offset relative to ground. Optionally, the voltage offset may be varied during electrophoresis analysis to slow migration during periods in which constituents are closely spaced and to speed migration when constituents are sufficiently spaced apart. A conductive capillary tube coating which is preferably grounded defines an external control area for electroosmotic flow. A detector is located downstream of the external control area, so that the coating is a unitary layer.
1. A method of controlling the rate of electroosmotic flow of a sample solution comprising,
providing an electrophoresis apparatus having a flow region,
inducing an electroosmotic flow of a solution within said flow region,
electrophoretically separating constituents of said solution, including applying a first voltage level to a first end of said flow region and applying a second voltage level to a second end of said flow region,
changing the rate of electroosmotic flow along said flow region during said step of electrophoretically separating constituents by adjusting the voltage levels at each of said first and second ends relative to ground, thereby providing a third voltage level to said first end and providing a fourth voltage level to said second end, the potential difference between said first and second voltage levels being substantially equal to the potential difference between said third and fourth voltage levels, and
continuing said step of electrophoretically separating said constituents at said changed rate of electroosmotic flow.
2. The method of claim 1 wherein said step of providing an electrophoresis apparatus is a step of providing an apparatus having a capillary tube defining said flow region.
3. The method of claim 2 wherein said capillary tube has an inner layer defining an inside diameter and has at least one outer layer, said method further comprising forming an outer layer by coating an area of said capillary tube with a conductive material, said step of forming an outer layer including leaving said first and second ends of said capillary tube free of said conductive coating.
4. The method of claim 3 further comprising electrically grounding said conductive material during said step of electrophoretically separating constituents.
5. The method of claim 3 further comprising detecting spatial separation of said constituents during migration through said capillary tube, said detecting being downstream of said coating and between said first and second ends of said capillary tube.
6. A capillary electrophoresis system comprising,
a capillary tube having a longitudinal axial bore and an outer wall, said capillary tube having an inlet end for introducing a sample solution into said longitudinal axial bore and having an outlet end,
supply means for applying a potential gradient along said longitudinal axial bore of said capillary tube to introduce electrophoretic migration of constituents of sample solution, said supply means generating an axially-directed electrical field along said capillary tube and a radially-directed electrical field perpendicular to said longitudinal axial bore, and
an external control means for affecting the magnitude of said radially-directed electrical field, thereby influencing a surface zeta potential of said capillary tube, said external control means including an electrical conductive coating on a portion of said capillary tube spaced apart from said inlet and outlet ends to leave said inlet and outlet ends free of said conductive coating, said external control means further including an electrical connection of said conductive coating to ground potential.
7. The system of claim wherein said conductive coating has a terminus spaced apart from said outlet end by a distance less than 4 cm.
8. The system of claim 6 wherein said means for applying a potential gradient includes a first high voltage power supply in electrical communication with said inlet end and a second high voltage power supply in electrical communication with said outlet end.
9. The system of claim 6 wherein said conductive coating is a nickel print.
10. The system of claim 6 wherein said capillary tube is a fused silica tube having a nonconductive coating, the outer diameter of said nonconductive coating defining said outer wall of said capillary tube.
11. The system of claim 10 wherein said nonconductive coating is removed at said detection means.
12. An improved electrophoresis system in which electroosmotic flow of a solution and differences in electrophoretic mobilities of solution constituents combine to create spatial separation of said solution constituents along a capillary tube having an inlet end deposited in a first liquid reservoir and having an outlet end deposited in a second liquid reservoir, wherein the improvement comprises,
adjustable means for applying a first high voltage to said first liquid reservoir and applying a second high voltage to said second liquid reservoir for selectively varying the rate of said electroosmotic flow of said solution within said capillary tube, wherein each of said first and second high voltages are selected to provide a desired spatial separation of said solution constituents within said capillary tube.
13. A method of controlling the rate of electroosmotic flow of a sample solution comprising,
providing a capillary tube having first and second ends and having an inner layer defining an inside diameter for the flow of a sample solution there along, said capillary tube having at least one outer layer including a conductive coating along a region of said capillary tube spaced apart from said first and second ends,
electrically connecting a first high voltage supply to said first end,
electrically connecting a second high voltage supply to said second end,
electrically grounding said conductive coating on said capillary tube,
selecting a desired axial potential gradient between said first and second ends of said capillary tube,
selecting a potential difference between said first and second high voltage supplies to achieve said desired axial potential gradient,
selecting magnitudes, relative to ground, of voltages for said first and second high voltage supplies to achieve said potential difference and to generate a desired radially-directed electrical field for spatial separation of constituents in a sample solution, said selecting of magnitudes being a selecting of voltages less than or greater than ground,
applying said selected magnitudes of voltages to said first and second ends, and
detecting said separation of constituents prior to exit of said constituents from said capillary tube.
14. The method of claim 13 further comprising adjusting both of said first and second high voltage supplies during said step of detecting said separation, including selecting adjusted magnitudes of voltages to provide a second rate of separation different from the rate of separation prior to said step of adjusting both of said first and second high voltage supplies.
15. The method of claim 14 wherein said step of adjusting both of said first and second high voltage supplies is a step of providing a corresponding adjustment, thereby maintaining said desired axial potential gradient.
The present invention relates generally to electrophoretic processes and more particularly to controlling electroosmotic flow in capillary electrophoresis.
Applications for electrophoresis, an analytical technique for separating and identifying constituents in a sample, include the determination of a sample's purity, the determination of molecular weights for proteins and nucleic acids, the mapping of nucleic acid primary structures, i.e. DNA and RNA sequence analyses, and the definition of phenotypic variance of a protein at the molecular level. Electrophoretic techniques rely on the fact that each molecular species has a unique combination of mass, size, shape, charge, density and sub-unit structure, all of which result in mobility differences responsive to an electric field. Various electrophoretic techniques use one or more of these properties to cause varying degrees of molecular separation via the migration of molecular species under an electric field.
Capillary electrophoresis is a technique using a capillary tube which is filled with a conductive fluid, as for example a buffer solution. A small amount of sample is introduced at one end of the capillary tube, whereafter a high potential difference is applied across the ends of the tube. Electroosmotic flow and differences in electrophoretic mobilities combine to provide a spatial separation of constituents of the sample solution at the outlet end of the capillary tube.
Electroosmotic flow is the movement of a liquid relative to a stationary charge surface as a result of an electric field applied to the liquid. U.S. Pat. No. 4,936,974 to Rose et al. explains electroosmotic flow as a result of charge accumulation at the capillary surface due to preferential adsorption of anions from the buffer solution that fills the bore of the capillary tube. The negative charge of the anions attracts a thin layer of mobile positively charged buffer ions, which accumulate adjacent to the inner surface. The longitudinally extending electric field that is applied across the capillary tube attracts the positive ions which are hydrated by water toward a grounded outlet end of the capillary tube, viscously dragging other hydrated molecules. This dragging of molecules applies to neutral and negatively charged molecules, as well as positively charged molecules. The result is a bulk flow of the sample in the buffer solution toward the grounded outlet end of the capillary tube. Consequently, electroosmotic flow provides a means for moving neutral and negatively charged constituents of a sample toward a ground electrode.
Electrophoretic migration is the movement of charged constituents in response to an electric field. A positively charged molecule will be accelerated through the electroosmotic flow toward the ground electrode. Negatively charged molecules may be repelled by the ground electrode, but the force of the electroosmotic flow overcomes the repulsion and advances the negatively charged molecules.
As a result, for an analysis in which a positive electrode is applied to the inlet end of the capillary tube and a ground electrode is applied to the outlet end, a spatial separation will occur with positively charged constituents exiting first, followed by neutral constituents and then negatively charged constituents. Each constituent of a sample may be identified by detecting the time required for the constituent to travel through the capillary tube. The quantity of the constituent within the sample is determined by the height and/or area of a signal trace on an electropherogram during a period of detection of that constituent. Ultraviolet detectors placed proximate to the outlet end of the capillary tube are commonly used, but other detectors are known.
Obtaining an accurate analysis requires that each sample constituent be moved to the detection area. Often, the sample is introduced into the inlet end of the capillary tube by insertion of the inlet end into a sample vial, whereafter the inlet end is inserted into a first buffer vial electrically connected to the high voltage electrode. The outlet end of the capillary tube is inserted into a buffer reservoir vial connected to the ground electrode. Upon initiating the separation procedure, a negatively charged molecule may be drawn into the first buffer vial before electroosmotic flow can take full effect. Thus, these molecules will not be detected, rendering the analysis less accurate. Another problem in obtaining an accurate analysis involves resolution of constituent detections. If a sample contains a number of constituents having similar electrophoretic mobilities, an analysis may be susceptible to errors in identifying and in quantifying the constituents. Yet another problem involves external factors, such as atmospheric conditions, that may have an effect on the electrophoretic separation.
It is an object of the present invention to provide a system and a method for increasing the effectiveness and reliability of electrophoretic separation and analysis. Another object is to provide such a system and method which may be used to reduce the setup time for analysis, as well as the migration time required for the analysis.
The above objects have been met by a system and method which, instead of influencing electrophoretic separation of sample constituents by factors directly related to the electrophoretic mobilities of the sample constituents, control the rate of electroosmotic flow. By controlling electroosmotic flow and by removing influences on electroosmotic flow, the analytical procedure is improved.
The system includes a continuous flow electrophoresis apparatus having a separation capillary. The separation capillary, typically a capillary tube, has an inlet end to receive a sample and a buffer solution and has an outlet end. A first adjustable power supply is electrically connected to the inlet end, while a second adjustable power supply is connected to the outlet end. Thus, the potential difference across the capillary tube is the difference between the voltages applied by the first and second power supplies. The potential gradient is then the potential difference divided by the length of the capillary tube between the connections of the capillary tube to the first and second power supplies. In a second embodiment, the second power supply is replaced by a resistive circuit electrically connected in parallel with the capillary tube.
A voltage offset relative to ground is used to control electroosmotic flow generated within the capillary tube. That is, while the potential difference and the resulting potential gradient remain constant, the first and second power supplies are adjusted correspondingly to increase or decrease the rate of electroosmotic flow toward the outlet end of the capillary tube. In a system in which the outlet end is at a lower potential relative to ground, an increase in the voltage offset relative to ground will increase the rate of electroosmotic flow, while a decrease in the voltage offset will decrease the rate of flow.
An advantage of the present invention is that the first and second high voltage power supplies may be adjusted to best suit a particular analysis. For example, if a sample has a number of constituents with similar electrophoretic mobilities, a voltage offset that ensures a slow constituent migration past a detector may be established to enhance resolution. On the other hand, the electroosmotic flow may be increased in order to provide a speedy analysis if the electrophoretic mobilities of the various sample constituents vary by sufficient amounts.
Another advantage is that the rate of electroosmotic flow may be varied during the separation procedure. The rate of flow may be increased during analysis of separated constituents having significantly different electrophoretic mobilities and may be decreased during analysis of separated constituents having similar electrophoretic mobilities. This is especially useful in an analysis of a sample having known constituents which are to be quantified.
In a preferred embodiment, the capillary tube has a coating of electrically conductive material on an outside wall of the capillary tube. As noted above, the electroosmotic flow is a result of ionic charge on the walls of the capillary tube. A conductive coating on the exterior of the capillary tube reduces the likelihood of creation of an undesired voltage gradient along the outside wall. A homogeneous field along the outside wall prevents external forces from affecting the ionic charge. An advantage is that the electrophoretic procedure is thereby more reliable. Preferably, the electrically conductive coating is placed at ground potential. This provides a defined reference point to the voltage offset created within the capillary tube. Grounding of the conductive coating can increase the surface zeta potential. Since zeta potential affects electroosmotic flow, increasing the zeta potential will increase the rate of flow for a given voltage offset and a given potential gradient.
Whether the conductive coating is allowed to float or is grounded, the coating reduces the likelihood of electrostatic charges at the outside of the capillary tube. Because of the thinness of a capillary tube, the capillary tube is susceptible to vibrations from electrostatic effects. The elimination of the electrostatic effects by use of the conductive coating provides an undisturbed ultraviolet detection of constituent migration through the capillary tube.
The conductive coating provides an external control area of the capillary tube. A difficulty associated with an external control area involves the optical coupling of a detector to the capillary tube. One solution is to form a window through the coating and to provide a conductive bridge across the coating. The present invention, however, utilizes a unitary external control area and places the detector downstream of that area. Thus, the detector which is coupled to the capillary tube to detect constituent separation while the constituents remain within a capillary tube does not affect electroosmotic flow.
FIG. 1 is a schematic view of a continuous flow electrophoresis system for controlling the rate of electroosmotic flow.
FIG. 2 is a graph showing the effects of varying the voltage offset of the system of FIG. 1.
FIG. 3 is a graph of the time of analysis required for electrophoretic migration with changes in voltage offset.
FIG. 4 is a second embodiment of an electrophoresis system for controlling the rate of electroosmotic flow.
FIG. 5 is a schematic view of an electrophoresis system having an external control area and a detector placed outside the control area.
FIG. 6 is a side sectional view of the capillary tube of FIG. 5.
With reference to FIG. 1, an electrophoretic system 10 is shown as including a capillary tube 12 having an inlet end 14 and an outlet end 16. The capillary tube is of the type known in the art. A fused silica tube having a coating of polyimide may be used. Such a capillary tube is flexible but has a material memory that urges the tube to return into a generally straight condition after flexing. The capillary tube has an inside diameter of 50 microns and an outside diameter that is typically in the range of 140 microns to 360 microns, but these dimensions are not critical.
A detector 18 is located along the length of the capillary tube 12. The polyimide coating is removed from the capillary tube at the optical coupling of the tube to the detector. In capillary zone electrophoresis, ultraviolet absorbance detectors are commonly used, but other detectors are known. For example, detection may also occur using a chemi-luminescence, refractive index, or conductivity detector. The optical coupling of the detector to the capillary tube permits detection of movement within the capillary tube.
The inlet end 14 of the capillary tube 12 is inserted into a container 20 having a sample vial 22. At the opposite side of the detector 18 is a buffer reservoir vial 24 that is in fluid communication with the outlet end 16 of the capillary tube. The buffer reservoir vial is housed within a container 26. The two containers 20 and 26 and the detector 18 rest on a table 28.
A first high voltage power supply 30 is electrically connected to the supply vial 22 via a power line 32 that represents an anode electrode. The first power supply 30 provides a high voltage, shown in FIG. 1 as -10 k volts, at the supply vial 22. However, this high voltage is not the potential difference across the capillary tube 12. The potential difference is determined by the voltage at the buffer reservoir vial 24. This voltage is provided by a second high voltage power supply 34 in electrical communication with the buffer reservoir vial 24 via a power line 36 that represents the cathode electrode. The second power supply 34 is illustrated as being set to provide a second high voltage of -15 k volts. Thus, the potential difference across the capillary tube 12 is 5 k volts. A standard potential gradient in capillary zone electrophoresis is 200 v/cm. To achieve this standard, the length of the capillary tube 12 would then be 25 cm.
Each of the high voltage power supplies 30 and 34 is a bipolar device having a polarity-select switch 38 and 40 to adjust the polarity of the associated electrode 32 and 36. Voltage-adjustment dials 42 and 44 allow a user to accurately set the outputs of the power supplies.
In the prior art, the potential difference of 5 k volts would commonly have been achieved by setting the anode electrode 32 at 5 k volts and the cathode electrode 36 at ground potential. For a given sample in such a system, the direct effect on sample constituents Would be the same as the system shown in FIG. 1. However, by using the first and second power supplies 30 and 34, the present invention provides a voltage offset relative to ground. This voltage offset and its effects are shown graphically in FIGS. 2 and 3. The conventional prior art voltage configuration is shown by line 46 as having an anode electrode 32 at 5 kv and a cathode electrode at 0 v. Line 48 illustrates the voltage gradient established by the configuration of FIG. 1. A third line 50 may be obtained by adjusting the polarities and the voltage outputs of the two power supplies. The voltage offset of the lines relative to ground affects the rate of electroosmotic flow within the capillary tube. That is, a change in the voltage offset changes the electroosmotic flow.
The graph of FIG. 3 illustrates the relationship between the voltage offset and the time required for analysis. Using a capillary tube having an outside diameter of 140 microns, the migration time is approximately 17 minutes if the cathode electrode is set at ground and the anode electrode applies a voltage of 5 k volts. In comparison, the voltage configuration of FIG. 1, in which the respective voltages are -15 k volts and -10 k volts, slows the analysis to one that requires more than 80 minutes. The reduction in speed is a direct result of a decrease in the rate of electroosmotic flow. Such a decrease would be beneficial where a sample to be analyzed includes a number of constituents having similar electrophoretic mobilities, since the resolution would be enhanced by the reduction in flow rate. In comparison, providing a positive voltage offset increases the rate of electroosmotic flow to provide a faster analysis for samples having constituents with electrophoretic mobilities which are sufficiently different that resolution is not a major concern. The effects of increasing the voltage at the cathode electrode while maintaining a potential difference of 5 k volts decrease as the voltage offset moves positively, but the effects are significant.
Also shown in FIG. 3 is a graphing of the results of similar adjustments of the high voltage offset in use with a capillary tube having an outside diameter of 360 microns. The curve is smoother than the graphing of the changes in migration time through the smaller capillary tube. This is at least partially explained by the use of a capillary tube having a grounded outside coating during the result plotting of FIG. 3. The grounded outside coating has less effect on a capillary tube having a thicker inside coating or coatings of dielectric material. The grounding of a capillary coating will be described more fully below.
Referring now to FIG. 4, a second embodiment of an electrophoretic system 52 is shown schematically as including a single bipolar high voltage power supply 54. The high voltage power supply has an adjustment dial 56 and a polarity-select switch 58. The output line 60 of the power supply is connected to the anode end of a capillary tube 62 and to a potentiometer 64. A center tap 66 of the potentiometer and a cathode end of the capillary tube are electrically linked. A resistor 68 provides a ground connection for the center tap and the cathode end. Thus, the voltage offset relatively to ground can be established by setting the desired anode voltage from the power supply 54, and then adjusting the potentiometer 64 to achieve the desired cathode voltage. Optionally, the potentiometer can be replaced with a resistor ladder, so that the resistance adjustment is precisely stepped. Moreover, the electrical connection between a single high voltage power supply and opposite ends of a capillary tube so as to provide first and second high voltages may be accomplished in other manners.
Referring now to FIGS. 5 and 6, electroosmotic flow can be further controlled by providing a conductive coating 70 on the outside wall of a capillary tube 72. Again, first and second high voltage power supplies 74 and 76 are shown connected to a supply vial 78 and a buffer reservoir vial 80 by power lines 92 and 94, respectively. The power supplies include polarity-select switches 96 and 98 and voltage-adjustment dials 100 and 102. The vials are in fluid communication with opposite ends of the capillary tube 72.
The conductive coating 70 on the capillary tube 72 may be allowed to float relative to ground. The conductive coating decreases the likelihood of an electrostatic field developing about the exterior of the capillary tube. Such a field would reduce the reliability of an electrophoretic analysis. Electroosmotic flow is a result of an electrical double layer of ions forming at the capillary interior as an electric field is imposed across the capillary tube. Consequently, any charge at the exterior of the tube has the potential of adversely affecting ion collection on the inside surface. The conductive coating 70 reduces the likelihood of a voltage gradient being created along the exterior wall of the capillary tube 72.
By "conductive coating" what is meant is a coating that may be used to establish or to eliminate an electrical field along the capillary tube, wherein the means of establishing or eliminating the electric field is by electrical conduction. The conductive coating 70 of the capillary tube 72 may be a nickel print on a standard polyimide layer 82 of a fused silica capillary layer 84. Deposition techniques known in the art may be employed. The thickness of the conductive coating 70 is not critical. Likewise, materials other than nickel, such as aluminum and conductive polymers, may be utilized.
In a preferred embodiment, the conductive coating 70 is grounded, as shown by ground lines 86 and 88 of FIG. 5. In addition to creating a reference point to the voltage offset of the tube 72, the grounding of the conductive coating potentially increases the surface zeta potential. Since zeta potential affects electroosmotic flow, increasing the zeta potential increases the rate of flow. As noted above and as shown graphically in FIG. 3, a grounded outside coating has less effect as the distance between the outside coating and inside diameter of the tube 72 is increased.
Returning to FIG. 5, the conductive coating 70 defines an external control area of the capillary tube 72. External control areas in capillary zone electrophoresis typically require users to form a window through the control area in the same manner that a window is formed through polyimide in a standard capillary tube 72. However, in FIG. 5 a detector 90 is placed downstream of the external control area. Preferably, the detector 90 is located within the final four centimeters of the capillary tube. The conductive coating 70 should be terminated at approximately two centimeters from the sample vial 78 to prevent an electrical short circuit to the vial. However, the optimal distance between the conductive coating and the sample vial will vary with the voltage applied to the sample vial. At the detector end, the termination depends upon the type and size of the detector. In use with an ultraviolet detector, if the mechanism can be narrowed to five millimeters in diameter, the termination of the coating would be the two centimeters needed to prevent shorting to the buffer reservoir vial 80, plus the additional 5 millimeters. Because the detector 90 is typically grounded, shorting between the grounded conductive coating 70 and the detector is not a concern.
Whether the conductive coating is allowed to float relative to ground or is grounded as shown in FIG. 5, the conductive coating 70 reduces the likelihood of electrostatic buildup at the outside of the capillary tube 72. Electrostatic buildup can cause vibrations of the capillary tube. By eliminating the electrostatic effects, the conductive coating can provide an undisturbed ultraviolet detection of migration through the capillary tube.
While perhaps the present invention adapts most easily to use in capillary zone electrophoresis, the invention may be used with other electrophoretic separation techniques, such as capillary isoelectric focussing which separates sample constituents by isoelectric point in a pH gradient formed over the length of a capillary. After the separation has been completed, electroosmotic flow may be employed in progressing the separated constituents past a detection device, with the electroosmotic flow being controlled by use of the present invention. This applies equally to isotachophoresis, which separates sample constituents by mobilities, and to micellar electrokinetic capillary chromatography, a form of chromatography which uses a "stationary" phase that is subject to electroosmotic flow.
Moreover, while the separation capillary has been illustrated as a single capillary tube, the separation capillary may include more than one capillary column and/or may have more than one inlet, as in the above-cited U.S. Pat. No. 4,936,974 to Rose et al.
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1. Heat the water in a pan until it starts to simmer.
2. Turn down to medium low and start putting in butter, piece by piece and mixing continuously.
3. If it gets too hot, the sauce will seperate. Make as much of the sauce needed using same amount of water.
4. Add salt, lemon juice and roasted garlic and mix.
5. Serve the dipping sauce with crab legs or lobster.


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ATLANTA (AP) — Well, someone's got to win.
Georgia Tech has lost three straight games, a skid that prompted coach Paul Johnson to fire his defensive coordinator in the middle of the season. Boston College is mired in a four-game skid, a stretch that has really turned up the heat on already embattled coach Frank Spaziani.


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Prestige Total Erase Modular Monthly Calendar System keeps track of important project dates. The three-month display offers a notes area on the bottom of each month and lined daily blocks from Monday to Sunday with the weekends slimmer and shaded. Innovative Total Erase panels easily switch places so the current month stays in the primary position. Ideal in frequently used group environments. Total Erase surface will not stain or ghost and resists dents and scratches, allowing new months to begin with a clean slate. Effectively display information in the generous notes area and date entry space. The patented "Easy Mount" hanging system delivers simple and accurate installation. The calendar includes four Quartet dry-erase markers and a convenient accessory tray. Contemporary, graphite finish frame and modern graphics make a bold impact.
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I've had this board for over 6 years and it's still going strong. I couldn't get by without it. It was every bit worth the money we paid for it. Definitely a quality product.
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JOHN SHINDLEBOWER for The Spencer Magnet
Logan Dunbar looks for a way to the basket in Thursday's matchup with Western Hills. The visiting Wolverines defeated the Bears 86-73 in the game, but Spencer County still sports an impressive 14-5 record on the season.
Spencer County Elementary kindergarten registration will be held March 1–5 from 8 a.m. to 3 p.m. This registration is for children who will be five years old by October 1, 2010 and are not currently enrolled in Spencer County Preschool. To be fully enrolled the following must be on file:
• Proof of residency
• A copy of the original birth certificate (not a hospital certificate)
• A copy of the student's Social Security card
• A current immunization certificate
• A physical examination form
A 22-year-old man has been indicted for murder in the Oct. 18, 2009, traffic incident that caused the death of a Taylorsville man.
Kevin Sullivan, of Mount Washington, is in the Bullitt County Detention Center on a $500,000 cash bond for capital murder and five counts of wanton endangerment.
According to a story in The Pioneer News, Sullivan was traveling north in the southbound lanes of US 31East in Mount Washington.
Twenty-four affordable apartments designed for low-income families has been scheduled to break ground later this spring, according to Roy Lowenstein, vice president of Buckeye Community Hope Foundation.
"These units will be very beautiful," said Lowenstein. "I think it will be an asset to the community."
The $4 million project called Taylorsville Place Apartments will be constructed on three acres located at Turnpike Ave. across from Spencer County Elementary School.
ROBIN BASS/The Spencer Magnet
Deputy U.S. Marshal Craig Smith (left) presented two Taylorsville police officers with certificates of appreciation at the city commission meeting last Tuesday. Lt. Rick Jewell (middle) and Chief Toby Lewis were recognized for assisting the U.S. Marshals in Operation Falcon June 2009. During the operation, multiple police agencies worked together to serve outstanding warrants and their efforts resulted in arresting over 1,000 fugitives in the Eastern district of Kentucky.
Property transfers
The following property transfers were recorded in the Spencer County Clerk's office during the month of November 2009.
The Seasons, LLC, Mt. Eden to Peoples Bank, Taylorsville. Lots 1 through 31 and Lots 33 through 36 Camp Branch Trail Subdivision. $775,000.
I was talking to a person not long ago and he said about the only time a lot of preachers liked to preach from the Old Testament was when they were preaching from Malachi about tithing.
DeMarcus Cousins. School is in, and school will soon be out for Kentucky's precocious big fella. Right? Maybe not.
ESPN's Jimmy 'gaga' Dykes, already suffering from acute John Wall Swoon, unilaterally promoted Cousins last week to second pick overall in Moneyball's June draft. Tall stuff for a kid one year removed from high school senior English.
Many patrons took a second look when they caught sight of the bright red Budweiser truck parked outside Settler's Trace Grocery Wednesday morning. Steve and Joan Killian's convenience store was the first in the county to receive a packaged beer license – and the first to legally sell alcohol – since voters elected to abolish prohibition in November.
Jeremy Tong was one of those patrons that had stopped to fill his car with gas. It was about 8 a.m. and he watched with interest as the driver wheeled in case after case of Bud Light.
Spencer County Community Action Network (C.A.N.) in conjunction with the Spencer County Youth Service Center is sponsoring a "Most Valuable Peer" Poster Contest, formally knows as "Get A Life." This contest is designed to recognize the youth of our community that make positive choices and serve as role models for others. If you know of an outstanding young person in grades 6-12, please complete a nomination packet and return it to the Youth Service Center or to the Cabinet for Community Based Services by Friday, February 26, 2010. Winners will be se
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What to Do in Milwaukee
Your first look at what's happening around Milwaukee. All of the latest events you can't miss in the city.
On Tap Today: New Year's Eve Events in Milwaukee
Want to dance on New Year's Eve? The Get Down at Turner Hall Ballroom is a great option, but there are literally dozens of fun ways to end 2013 in style. Photo by Angela Morgan, courtesy of Turner Hall Ballroom.
We're just hours away now from the end of 2013. Have you made your plans yet?
Still undecided? We're here to help.
Wanna dance?: Consider the Get Down, a dance party featuring '60s and '70s soul and funk spun on original vinyl (including little heard and long forgotten Milwaukee songs), at Turner Hall Ballroom. »Read Full Blog Post(1)


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January 19, 2015
This is a very bright light
November 13, 2014
This product was bought specifically for whilst i am out working in the dark and its serves its purpose without a doubt.
Just right to fit in a pocket for the winter nights and makes good presents
October 28, 2014
Can be used anywhere, hanging facility useful and very bright light
October 26, 2014
Very good portable light
This does not affect your statutory rights
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Select Local Merchants
The Reptile ZooRead MoreThe Reptile Zoo is home to more than 100 exotic species of reptiles, amphibians, and arachnids. Some were rescued and brought here, some were born here, and others hitchhiked here after reading about the zoo's excellent conditions. The zoo invites you to explore and learn about all its many creatures, whether through interactive displays or live presentations. Some hands-on opportunities at the zoo may include wearing an eight-foot Burmese python around your arm or feeding hungry beasts in the hands-on feeding zone. During a visit, you might also meet a celebrity in Frank, a 65-pound lizard better known as Mr. Kipling on The Disney Channel's Jessie.18818 Brookhurst StFountain Valley, CA US
Pacific Marine Mammal CenterRead MoreThe Pacific Marine Mammal Center offers its visitors the chance to add a sea lion to their family trees. Through symbolic adoptions, the non-profit organization funds its mission to locate, rehabilitate, and release injured marine mammals?including seals, sea lions, and dolphins?back home in the wild. After admitting one of these animal patients, the Pacific Marine Mammal Center's animal-care director and a veterinary medical director can administer antibiotics, nurse mammals back to health or go through treatment plans for various diseases and illnesses. Aside from adoptions, the center educates the public about these efforts through programs such as field trips and day camps for kids.20612 Laguna Canyon Rd.Laguna Beach, CA US
ZoomarsRead MoreA rustic Spanish-style farm in the heart of San Juan Capistrano that's been standing since 1890 promises more creatures than just the area's famous swallows. The picturesque estate is part of Zoomars?an all-ages petting zoo that's USDA-approved for cleanliness and the place where more than 200 animals call home. The residents range from the familiar to the exotic: goats, sheep, and kunekune pigs mingle alongside exotic emus, zebus, and zebras that greet visitors for pets and feeding. One of the zoo's most popular areas is the guinea-pig patch, where some of the farm's fuzziest and friendliest creatures reside. Zoomars also features family-friendly attractions ranging from a miniature train and pony rides to the newly installed playground with four slides to the rustic Miner's Gulch, where panning the water reveals rare treasures such as gemstones. Meet the Owner Owner Carolyn Franks started down the path to animal care in college when she created her own line of dog toys. She soon moved from New Jersey to California where her passion snowballed: developing a full line of pet products, hosting an animal show for kids, running a chain of exotic bird stores, and even traveling to Brazil to learn about animal conservation. In 2005, she used her knowledge to take over the Jones Farm petting zoo, expanding its pens and transforming its brand into Zoomars. Franks is joined by a well-trained staff of zookeepers and wranglers who share her vision in entertaining kids?and teaching them how to interact with the animals?as they are in caring for and shepherding mammals and birds.31791 Los Rios St.San Juan Capistrano, CA US
Enchanted Country Trees & PumpkinsRead MoreWhile the rest of the natural world prepares to hibernate for the winter, Enchanted Country Trees & Pumpkins has been at its most active since 1983. Farmers pick the plumpest pumpkins from their patches, displaying them next to bounce houses and trundling John Deere tractors. Barnyard animals deign to be petted in exchange for palmfuls of feed, and ponies accept small riders for afternoon trots. Come winter, the lots fill with Christmas trees.5840 Walnut Ave (at Jeffrey)Irvine, CA US
Rancho Las Lomas Wildlife FoundationRead MoreZiddle and Zaddle the zebras, a alpaca named Cletus, and a Bengal tiger that eats from a zookeeper's hand all sound like characters from a charming children's book?but these animals are the real-life residents of the Rancho Las Lomas Wildlife Foundation. Home to animals from around the world and myriad plant species, the zoo serves as a educational resource for locals and educational establishments. Visitors can take behind-the-scenes tours or explore the grounds for themselves, chatting with macaws, watching the servals play, and staring at a white Bengal tiger until they can see the 3D picture in her stripes.19191 Lawrence CanyonSilverado, CA US
Pumpkin City's Pumpkin FarmRead MoreUnder strings of lanterns and the night's canopy of stars, kids scamper through a field filled with thousands of pumpkins, each one searching for the biggest, roundest one. Finding it is one thing; lifting it is another. The bountiful Pumpkin City's Pumpkin Farm began a bit by happenstance?the owners originally began selling pumpkins out of the back of their pickup and steadily added on amusements as more people came each year. More than 30 years later, the one-month harvest festival sets up each October with attractions ranging from pony rides to puppet shows. As they explore the area amid bales of hay, teepees, character cutouts, and other props, kids can feed baby goats and sheep at the petting zoo or sit on an authentic tractor from 1932. Once guests have procured the perfect pumpkin to carve into the likeness of their favorite monster, they can get their picture taken with Pumpkin Jack, hop on rides such as the Goliath Slide or Pumpkin City Express Train, or visit Gone Fishing, Knock 'Em Down, and other game booths.24203 Avenida De La CarlotaLaguna Hills, CA US


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Meeting Incubus for the second time!
"Aww this is so lovely! The little girl is super cute, haha, mini Incu fan. ^__^"
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Town Square
Creek Cleanup
Original post made by John Guislin, Crescent Park, on May 9, 2007
A group of citizens from Palo Alto and Menlo Park have received approval to cleanup a section of the creek between the Middlefield and Chaucer bridges. Both cities have granted us access rights and Palo Alto Public Works will haul away the trash we remove.
Meet Saturday May 19 at 9am at the creek access ramp on Woodland Ave. in Menlo Park, about 100 yards downstream from the Middlefield bridge. Wear boots, bring a hat and help preserve wildlife and reduce flood risks in one of the few remaining natural creek channels.
Questions: contact firstname.lastname@example.com
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Calave wine bar opens in Palo Alto
By Elena Kadvany | 12 comments | 2,865 views
OK I Changed The Title
By Laura Stec | 21 comments | 1,422 views
Family Outing - Inside Out
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Relay for Life, Menlo Park, August 8
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TORONTO -- Ryan Hanigan returned to the Red Sox quicker than the doctors expected when they told
TORONTO — So caught up in the deflating loss Rick Porcello led the Red Sox to yesterday, we
TORONTO -- At least everyone agreed Wednesday, after Rick Porcello got lit up like a Canada Day f
TORONTO -- When right fielder Jackie Bradley Jr.
TORONTO — With a chance to capture their first four-game winning streak of the season and p
TORONTO -- With the trade deadline approaching at the end of the month, Red Sox owner Joh
TORONTO -- Happy Canada Day!
TORONTO -- It sounds like Hanley Ramirez will return to the Red Sox' lineup
TORONTO -- Clay Buchholz can't stop raving about c
TORONTO — Two games, two runs scored for the Blue Jays' top-ranked offense against th
Jason Mastrodonato has covered the Red Sox since 2011 and joined the Herald in 2015. A graduate of Northeastern University, he previously covered the team for MLB.com and MassLive.com.
Scott Lauber has covered the Red Sox for the Boston Herald since March of 2010. Previously, the Boston University graduate was the Philadelphia Phillies beat reporter for the Wilmington (Del.) News Journal for five seasons, during which time he covered two World Series and co-authored "Phillies Confidential: The Inside Story of the 2008 World Series Champions." A three-time Northeast Regional Associated Press Sports Editors award winner, Lauber also covered the New York Mets' farm system for the Binghamton (N.Y.) Press & Sun-Bulletin and Hockey East for the Concord (N.H.) Monitor.


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Boys basketball
Schroon 63, Westport 11
Schroon Lake crushed Westport, 63-11, in Mountain and Valley Athletic Conference boys basketball play Jan. 31.
Photo Gallery
Schroon Lake v.s. Westport boys basketball
Schroon Lake win against Westport with a final score 63-11
The Wildcats raced to a 16-3 lead and held a 41-6 edge at the intermission.
Ian Williams scored 21 points for the 'Cats.
Jesse Shaughnessy added 18 points for the winners, while Uriah Harvey had nine points, 12 rebounds and four blocked shots.
Crown Point 43, Wells 41
Nathan Tabor was the hero, hitting a three-pointer at the buzzer, as Crown Point edged Wells, 43-41, in Mountain and Valley Athletic Conference boys basketball play Jan. 31.
The Panthers trailed the entire game until Tabor's game-winning hoop. Crown Point was down by seven points with two minutes remaining, but rallied as Wells missed several free throws that could have iced the game.
Jake Courcy had 14 points and Mike Gould 13 to pace the Panthers. Tabor had eight points.
Girls basketball
AVCS 60, Moriah 35
Moriah fell to AuSable Valley, 60-35, in Champlain Valley Athletic Conference girls basketball play Jan. 31.
The Patriots grabbed an 18-4 lead and never looked back.
Meghan Strong tallied 18 points to pave AVCS
Hayley Waldron scored 17 points and hauled down 10 rebounds for Moriah.
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Stakes are high at greyhound track Saturday
The biggest dog race in Southwest Florida history goes down Saturday in Bonita Springs.
At 7 p.m., the Naples-Fort Myers Greyhound Track kicks off its first derby since 2002, a night of stakes races culminating in a $50,000 competition.
"Saturday is the time to be here for some great greyhound racing," said Larry Mosher, director of racing at the track. "This is the richest stakes race ever at Naples."
The event is the culmination of a two-month-long celebration at the Bonita Springs track, marking the 50th anniversary of its opening. The anniversary day was in December, and the track has had festivities several times a week to mark the occasion.
All of the other 50th anniversary events have had large crowds, so the track is expecting one of its largest turnouts since the turn of the century.
"It should be a fun night," general manager Larry Baldwin said. "This is the $50,000 Anniversary Classic."
In addition to the $50,000 race, four other stakes races with large purses will be held Saturday night. All of the stakes will be of varying distances including a 990-yard supermarathon where the dogs run two and a half laps around the track. Naples-Fort Myers hasn't had a supermarathon since 2002.
The highlight of the evening is the derby, the 11th race of the night starting sometime after 10 p.m. The competition has brought some of the fastest dogs from around the country, whose owners are all after the $50,000 purse. The field has been narrowing for a month in qualification races. The fastest dog in the competition will bring home 50 percent of the purse. The field will split the rest.
The odds-on favorite in the derby is Magic Penny Ante who has won 11 races in a row.
"This is exciting where all eight dogs could win the race," Mosher said.
One of the local favorites is Grey's Swing Gate. The dog is raised by Naples residents and has Naples-Fort Myers as its home track. Gil's Cisco is another dog in the derby that calls Naples-Fort Myers home.
As part of the celebration, the track will have country artist Billy Pierson singing throughout the night, have $50 voucher drawings, prize give-aways and draft beers at two for $5 in the grandstand, where an outdoor BBQ will be held. The clubhouse prime rib buffet is almost sold out at 90 percent reservations.
Naples-Fort Myers used to have an annual derby, which was a big night for the track, but it was discontinued in 2002 after audience interest dwindled. With a big enough turnout on Saturday, track officials hope to launch an annual derby once again.
"We're excited," Mosher said. "It will be a black tie event for us."
Crowds were starting to swell already on Wednesday afternoon, with a larger than usual crowd for the matinee races.
"Everybody likes to come to the dog track," said Bitsy DelVecchio, who lives part-time in Naples. "We just love the track."
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The dogs running in Saturday's $50,000 Anniversary Classic in Bonita Springs, and each dog's odds (as of Wednesday morning):
1. Gil's Cisco, 4-1; 2. Invincible Son, 2-1; 3. Magic Penny Ante, 4-5; 4. Hallo Arouser, 7-1; 5. Grey's Swing Gate, 15-1; 6. BF Roseway, 12-1; 7. Atascocita Jacey, 15-1; 8. Atascocita Primo, 15-1
Subscribe to the Naples Daily News
Need Help? Call us at 1-888-878-6842.
Monday-Friday: 6am-6pm / Saturday: 7am-3pm / Sunday: 7am-2pm


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YIELD: Serves 4
Sauté the onion and garlic in hot olive oil until just soft. Add the rice and seasonings and brown lightly. Add the mushrooms and sausage and enough boiling stock to come 1" above the rice. Cover with a tight lid and bake in a 350°F. oven until the liquid is completely absorbed, about 35 minutes. Sprinkle with grated Parmesan cheese and serve.


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The Mr. Good Lookin' Is Cookin' is a funny apron that is not only a bbq apron, it is a humorous kitchen apron and a great gift idea for your favorite foodie. "Mr. Good Lookin' Is Cookin'" is screen printed onto a generously cut, full sized bib apron made of durable (7 oz.), machine washable 65/35 poly-cotton twill. Avoid the cheaper vinyl transfer BBQ and kitchen aprons; keep the food and the laughs coming with the screen-printed Mr. Good Lookin' Is Cookin' Funny BBQ and Kitchen Apron!
Mr. Good Lookin' Is Cookin' Funny Apron Features:
- Not just a BBQ Apron, is a funny Kitchen Apron
- Screen Printed NOT Cheap Vinyl Transfer
- One Size Fits All
- Machine Washable
- 33" Long x 29" Wide


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Special Offers
Come to The Dunhill Hotel and experience unparalleled service and "modern Southern" cuisine. The Asbury celebrates the best of what the South has to offer in ingredients, technique, creativity, and, of course, hospitality. The Asbury is a tribute to Chef Coleman's Southern roots and the culturally diverse community of the New South. Package includes overnight accommodations, a dining credit of $100 (for use at The Asbury or the lobby bar)*, and our complimentary Artisanal European breakfast. Dining reservations strongly recommended to ensure preferred dining time. Taxes and gratuities are not included.
*Dining credit must be used by checkout. Dining credit does not have cash value and any unused amount will not be refunded.
Indulge in a romantic getaway in the heart of Uptown Charlotte. After you make your reservation, our concierge will call you to help plan an unforgettable evening. We will arrange everything, from dining reservations to horse-drawn carriage rides. A bottle of champagne and our house-made chocolate truffles await you in one of our elegant guest rooms. The romance continues with rose petals sprinkled across your bed during our evening turndown service. In the morning, enjoy a complimentary Artisanal European breakfast.
Package includes overnight accommodations, a welcome amenity from the Bechtler, two Bechtler Museum of Modern Art admission tickets, a special 10% discount in the museum store, a glass of wine for each guest, a sampler of local cheeses at The Dunhill Hotel's lobby bar, and our complimentary Artisanal European breakfast. Please note the museum is closed on Tuesdays.


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Taynara Julianna
Aproveite cada dia como se fosse o último!!! :)
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#whindersonnunes tô aqui por ti hehehe
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Eu ganhei doces no #AniversárioDoGoogle! Pontuação: 106
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Não se envergonhe :))
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Bebe cochilando que lindo!
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Falou tudoo!! Esse programa "Maior brasileiro de todos os tempos" virou uma grande PALHAÇADA!!!! Como pode nós brasileiros acabarmos com nossa propria "imagem"!!! Recomendo que todos vejam esse video!!!!!!!!!!!! :/
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"Porque "já" quer dizer agora, e "já, já" quer dizer daqui a pouco?"
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A fortuna faz amigos. A desgraça prova se eles existem de fato.
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Pikachú es real
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South Plainfield resident accepted $13,000 in windows and doors
Robert A. Berman of South Plainfield, the former Westfield School District business administrator, was given a year of probation Friday for accepting $13,000 in windows and doors from a contractor he recommended be hired by the district.
Berman, 55, received probation from state Superior Court Judge Joseph P. Donohue in Elizabeth. Berman pleaded guilty on Oct. 24 to a charge of third-degree conspiracy to make false representations for a government contract. He was required to forfeit his positions as business administrator and Westfield school board secretary. He was also ordered to pay a $6,000 penalty into the state's Anti-Trust Revolving Fund for anti-trust enforcement efforts.
In pleading guilty, Berman admitted that he accepted the roughly $13,000 worth of window glass and doors installed at his home by Metropolitan Metal Window Co. from 2004 to 2008. He further admitted that, as business administrator, he issued written recommendations that the school board to appoint Metropolitan as the district's "contractor of record" and he approved contracts knowing that they contained false information.
Berman was charged in March as a result of an investigation by the state Division of Criminal Justice Corruption Bureau, which also led to charges against a school district engineer and three contractors. The engineer and two of the contractors have pleaded guilty. Charges are pending against the third contractor, who is the co-owner of Metropolitan.
Suspended Westfield schools' administrator Robert Berman pleads guilty to contractor scheme
The school district engineer, Kenneth Disko, 48, of Mountainside, was the contracted engineer or engineer/architect on record for the Westfield, Tinton Falls and Scotch Plains-Fanwood school districts. Disko pleaded guilty on Oct. 12 before Judge Donohue to taking thousands of dollars in kickbacks from 2001 to 2010 on contracts he recommended that involved rigged bids and fraudulently inflated costs. His sentencing is scheduled for March 2. The state will recommend that Disko be sentenced to three to five years in state prison, pay a penalty of at least $50,000, and be barred from public contracts in New Jersey for 10 years.
Disko admitted that he knowingly prepared fraudulent quotes and estimates in connection with school district contracts, and directed contractors to inflate quotes and estimates. He also admitted that he submitted those quotes and estimates to the Westfield, Tinton Falls and Scotch Plains-Fanwood school districts and recommended approval of the fraudulently bid contracts in exchange for thousands of dollars in kickbacks from contractors.
On Dec. 1, two contractors pleaded guilty to rigging bids and inflating school contracts at the direction of Disko. Martin W. Starr, 45, of Cliffwood Beach, owner of Starr Contracting, and Stephen M. Gallagher, 51, of Cliffwood Beach, owner of East Commercial Construction, pleaded guilty to accusations charging them with third-degree false representations for a government contract before Superior Court Judge John S. Triarsi in Elizabeth.


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This image is presented as a "thumbnail" because it is protected by copyright. The Brooklyn Museum respects the rights of artists who retain the copyright to their work.
The Drape
- Artist: Carl Lewis, American, born 1951
- Medium: Cibachrome print
- Collections:Photography
- Museum Location: This item is not on view
- Accession Number: 87.152.1
- Credit Line: Gift of Foster Goldstrom
- Rights Statement: © artist or artist's estate
- Caption: Carl Lewis (American, born 1951). The Drape. Cibachrome print Brooklyn Museum, Gift of Foster Goldstrom, 87.152.1. © artist or artist's estate
- Image:
- Record Completeness: Adequate (50%)