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Encinitas attorney who has studied agency extensively gives expert's perspective on clinical trials
The Food and Drug Administration decides which drugs and medical devices can be sold in the United States, based on clinical studies of their safety and efficacy. Biotech and drug companies, clinical researchers and, of course, patients have a strong interest in how the agency does its job.
Attorney Michael Swit has closely studied the FDA for nearly three decades. He's knowledgeable on a wide range of FDA-related subjects, including regulations for clinical trials, product marketing and corporate acquisitions of regulated companies.
Swit tells companies how to avoid common mistakes, advises them on how to keep records correctly, and answers the myriad questions that arise from dealing with a complex regulatory agency.
In short, Swit is the kind of expert drug and medical device companies with hundreds of millions of dollars at stake want on their side.
Swit has published numerous articles about the FDA in legal journals and other publications, frequently gives presentations about trends in life science regulations, and co-designed and directed the first intensive course on the FDA's generic drug approval process.
Moreover, Swit brings an industry perspective to his work. He was the top attorney for major generic drugmaker Par Pharmaceutical in the early 1990s. At Par, Swit dealt with federal and state investigations regarding conduct of previous management. Since then, he has worked for several law firms as well as practicing on his own. He's now special counsel in the San Diego office of Duane Morris LLP.
An Encinitas resident, Swit has just published a book, "Good Clinical Practices: A Review of FDA's Enforcement Activity." At a price of $377, the book isn't meant for casual readers but for those professionally involved with clinical trials.
U-T San Diego asked Swit about the book and other FDA-related matters in a recent interview.
Q: What does the book discuss?
A: It focuses on FDA regulation of clinical studies. It includes a detailed review of "warning letters" the FDA issued over the past 33 months, from January 2010 to September 2012. (Warning letters point out a violation that must be corrected.) Good clinical practices is an absolute necessity, not only for insuring the protection of human subjects, but also the integrity of the data collected so the FDA can rely on it.
Q: What will readers learn from the book?
A: I write about the "hot buttons" — what the FDA focuses on, what are the most common observations alleged in a warning letter, and the circumstances under which the warning letters arose.
Q: The FDA has veered over the years between being more aggressive in getting new drugs to patients who don't have any good alternatives and keeping bad drugs off the market. Which does it now stress more?
A: I think the pendulum right now is clearly on the safety side. This has been evolving since (the painkiller) Vioxx was pulled off the market in September 2004.
There are major concerns over allegations that certain SSRIs (a class of antidepressants) such as Paxil had not been properly labeled for potential suicidal ideation in teenagers. This year we learned about the pharmacy issue with the compounding center. (The New England Compounding Center allegedly caused a meningitis outbreak by distributing contaminated steroids. The Framingham, Mass.-based company filed for bankruptcy in December.)


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Tides of Time: The Uncertain Future of Ecco the Dolphin
Ecco Creator Ed Annunziata talks about his inspiration for the undersea classic, and his goals to bring The Big Blue to the modern era.
by Tyler Winegarner on
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Awesome interview.
So great to see the creator of the original Ecco games and hear him talk.
I didn't know about the Kickstarter project but, even if I did, I don't know if I would have donated. Even after hearing his description and seeing the preview, I have no idea what this game would be.
Would it be available for PC or just portable devices?
Why did he express an interest in helping people to become more aware about the impact they're having on the Earth while having the game set in a future where the negative impact of humans ultimately produced a positive result?
Anyway .. I'll be looking forward to playing Little Blue to see what he has in mind (assuming it'll be available for PC).
Thank you for doing this interview!
PS: If I were rich, I would've donated simply because he's the creator of the original Ecco games.
PPS: I wish he could get the rights to create an Ecco sequel.
this game gave me my fear of drowning
راحت ايامك يا دلفين اتمنى يسون جزء ثالث
اتمنى ذلك
Dam! Just found out about it... if only i knew there was a kickstarter for this game :(((
This literally almost brought me to tears watching this. I love the Ecco the Dolphin series. The Sega CD (Definitive) versions, the soundtracks are mesmerizing. I have them on my iPhone and always listen to them. The Dreamcast version, blew me away at the time and still does to this day. One question though, what is the name of the music playing in this video? It sounds like Carbon Based Lifeforms. I just hope this game makes it's way to consoles instead of the iPhone/Pad.
I notice there was no mention or footage of the Dreamcast game. Did he work on that one?
This guy speaks with real passion towards nature, or he is really good in acting.
I would love to see more games that strive to create the sensation of being an animal, that take us into that alien realm of experience.
i lost a bit of interest when i saw it running on a tablet :/
This man reminds me of george lucas for some reason.
I was once an adventurer like you, but then I took a harpoon to the knee.
I love Dolphins xoxo
omg i remember playing this game and there was a glitch i forgot where but it always froze the game haha good times
Can't believe we live in a world where an Ecco the Dolphin needs a kick starter but CODs sell like hot cakes...
I remember playing these games back in the day. Would love to see how they would play with todays technology.
I remember the part where you have to swim through a DNA looking thing, it was a great game still have great memories when i beat it with my brother last area was a pain.
Ha. Nostalgia. I STILL have this, and actually popped it in last year for laughs. When I think of my Sega Gensis, this is definitely one of the games I think about. I'd love a remake haha..
Just make it an adventure game. Wonderous, beautiful, huge, vivid, detailed, and alive.
Ecco: The Dolphin.
wtf forgot all about that crap
Seriously, can we please get an awesome remake of Ecco?! Just remake and redo the 2D version and then make a 3D game to come along with it.
Haha, worst mega game drive ever!!!!
I would love a true next gen Echo game. The one on the Dreamcast looked AMAZING for its time. Imagine what could be done now.
I'm not too into his vision for the future though, that happens to have dolphins in.
A true echo game though? Of course!!!
Would also love a new Panzer Dragoon
Yes! Very interesting game that was, and it had very interesting graphics as well. Both my daughter and I play it on the Sonic Ultimate Sega collection disc all of the time. The new game could could make good use of the next gen power
very well done vid! good idea shooting it at the sf aquarium, it's near to impossible for footage of jellyfish to make anyone bored XD
hell yes
I ADORE Ecco! Haven't played Defender of the Future (though it looked very interesting and clearly followed in the same unnerving weirdness as its predecessors), but the first two games are great. You never forget your first foray into 'Welcome to the Machine' (swiftly followed by your second, then your tenth, then your twentieth...)
Loveeeed this as a kid.
Pleeease make another game like Defender of the Future. That game was dooope
Ecco is a classic now? Doesn't a "Classic" have to be universally praised by critics and consumers alike to actually be a classic? Because that game wasn't that.
You know, in a million years, dolphins would not be the same species we call dolphins, they actually might walk on land, or have wings, but the end result won't be dolphins. It's too bad the kickstarter didn't make it. The advertising was missing from this crowd funding, I didn't even know until today this was going on, big mistake. Well, best of luck to them, maybe Sony can fund it, they funded Journey, and look how great that game is.
Give it multiplayer, ranks, prestiging and kill streaks and idiots will buy it...
Great reporting! Excellent filming and it's awesome to hear from someone responsible for creating one of gaming's legends. Inspiring! I hope his work flourishes. Thanks Gamespot!
Making a good video game is hard enough, making one about a dolphin seems like it would be even tougher.(although he does have something to go off of) Kudos to him if he can pull it off.
Euh ... man I thought that game was a relic from the past and I'm surprise they ever thought of bringing it back ... this is something that I find wierd this gen ... we don't need a reboot or a HD version of everything made in the past ...
@lostn As far I know, he did not work on the Dreamcast game. The people who created the Dreamcast game clearly tried to capture the spirit of his two Ecco games though.
@Chris_Watters Seeing a new perspective is always a satisfying experience. And the world of the mundane to one person is an absolute mystery to others. Game designers should always test the boundaries of what becomes familiar and alien when they are creating or revitalizing an idea. Ecco has always been a new experience, and I look forwards to seeing what they can do with it with modern graphics.
@TheFallen924 agreed
@jazilla No, a classic doesn't always need to have everyone's approval. Speaking as a long time fan, Ecco had it's flaws, the two biggest being that the level design had an annoying tendency to resort to mazes and there were far to many enemies in certain stages, but it was unique and largely well made, not to mention it has a pretty large fan base.
So for all intents and purposes it is a classic.
@Ryuuken27Great White sharks have remained the same for over a million years. Bottlenose dolphins could too. Currently they are being poisoned badly by humans though, so they, like millions of other species, may go extinct before they can further evolve.
Interesting side note: In Ecco: Tides of Time, the dolphins of the future have evolved to have the ability to fly (among other things).
@rocketsatdawn To be honest I don't think it's going to work, I love ecco and would like to see a return, but I don't think enough people aside from the fans do.
They really should have stirred up some hype before just going for crowd funding.
@Coco_pierrot Well, I kinda agree with you there. I mean, I Iike reboots because they keep my childhood favorites alive and available on newer systems. But It does kinda bug me when there are nothing but reboots for a certain time period. For me an Echo game refit into a new game sounds interesting to me, because it's the only game I know where I play a marine sea creature as a main character and if they adapt the title right, can be a very refreshing game than what we've been playing.
@penpusher I think the term "classic" should be reserved for those games that are universally praised. When my friends and I talk about classic games, Ecco doesn't even come up in the discussion. Games like Perfect Dark 64 and Zelda and Tomb Raider and Resident Evil and Super Mario Bros. come up in convos though. Those are classics.
@BeKindXII I was just being fictitious about it. Who knows when the next ice age is going to hit the planet, or what will happen when the poles shift position, what kind of hell it's going to create. A lot of animals on land are going to become extinct, that's for damn sure.
@penpusher @rocketsatdawn I would have liked to have seen a true echo game. Not one just based off a game under the sea, with life etc, that happens to have dolphins in it.
@Rizer Yeah you are right that it will be refreshing in this FPS plagued world even if it is the second reboot
@penpusher @jazilla dito to that ^^. Resident Evil a classic? Really?
@jazilla All I can say to that is that it's a good job that what you think, and what actually is, are two very different things. Just because you personally don't think it is a classic, doesn't mean it isn't.
@RoOhDiNi @jazilla @penpusher ^^this
When I think about SEGA, I think about Sonic, Ecco, Panzer Dragoon, Jet Set Radio - So yeah, it is a classic to me.
Shenmue also wasn't praised or even experienced by many - still it is a classic SEGA game for it pretty much sums up what the Dreamcast was all about and perfectly reflects the console's ambitious nature!

subset: commoncrawl


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Draft Breakdown Debate: Ryan Lownes vs. Rob Engle
4. Which player's character concern worries you the most? And who of the guys with "questionable" character are you least worried about?
ROB: Ryan Mallett was said by one scout to "think he's Eminem". There are different ways to react to this thought. The immediate reaction I had was to take him off my board completely. And, then the conspiracy theorist kicked in and I thought, what if a team was just trying to knock him down another teams' board? The NFL Draft is all about smokescreens. Watch this interview of Ryan Mallett from the combine provided by CBS Sports (click here) . Of course it's only a short video with some very scripted answers in front of the media, but you can still attempt to read his mannerisms. I can't speak of Mallett's alleged drug use because I don't think anyone but the 32 NFL Teams and people close to Mallett has the answers. But I think the way Mallett tried to quickly move past the questions about drug use rather than addressing them upfront and honestly is alarming and makes me really worry about his future. No matter how impressive he may be as a prospect, I wouldn't touch him at all.??Someone who did use the combine to properly address his character concerns was Colorado Cornerback Jimmy Smith. In his interview from the combine (click here) he takes time out his interview to specifically address his past. While he doesn't want to get into specifics, he does admit to making "young mistakes" that we know was a failed drug test. I think it obviously depends on what the drug he took, but Teams are understanding of a college environment and can get past a players past if they feel comfortable that he has matured. I personally love his confidence and like his mentality and think that the way he addressed his issues at the combine will help his draft stock tremendously.
RYAN: Rob, I'm going to be a little all over the place here, so stay with me. I personally disagree with your ideas on Ryan Mallett's character. While he does not articulate particularly well, he showed intelligence in the way he ran Bobby Petrino's complex offense at Arkansas. His Wonderlic (26) was nothing subpar and I have confidence in his football IQ. Though a bit emotional, I love his competitive nature and it is easy to see that teammates rally around him. He gets a hard time because of that thick Southern accent and the overall way he carries himself, but he has obviously matured a whole lot since his days at Michigan. As with Mallett, I think North Carolina Wide Receiver Greg Little is receiving a bit too much bad press. Though he sat out the entire 2010 season for receiving improper benefits, he acknowledges his mistakes, expresses remorse, and is now looking forward to the NFL. In interviews I have come away impressed by his speaking ability and intelligence does not seem to be a concern (click here). His character does not worry me all too much and I believe he will be a steal for the team that nabs him in the Third Round.
Now, moving on to a couple prospects that do scare me a bit more, we have a couple Defensive Tackles: Auburn's Nick Fairley and North Carolina's Marvin Austin. Like everyone else that closely follows SEC football, it pleased me to see someone play with the ferocity and intensity of Fairley. Unfortunately, Quarterbacks are huge financial investments in the NFL and are protected accordingly by the league's rules. His on-field discipline is certainly worrisome, as he seems to lack control over his emotions. What is more concerning, however, is his lax approach to practice and conditioning. As a guy with a JuCo background, there are serious doubts about his intelligence, and there is reason to believe he is simply not prepared for the rigorous demands of being a professional. Austin, on the other hand, has been described by many as a "punk." He is a player that just does not seem to grasp the importance of maintaining a positive self-image. Like Little, he was another of the Tarheels that missed the 2010 season due to suspension. Though he is an athletic wonder for his size, I worry he may lack the maturity needed to put it together on the field. I wouldn't touch him in the Top 100 picks personally, but it only takes one team to fall in love.
5. Who would you take to be your franchise QB, Cam Newton or Blaine Gabbert?
RYAN: This may be the easiest question of the bunch for me, as I would take Cam Newton every time over Gabbert without hesitation. The Heisman Trophy itself does not point to NFL success, but it is indicative of the best player in college football. Without doubt, Newton was just that. In leading his Tigers to a National Championship, he showed he would do whatever it took to dominate opposing defenses and win games. Everyone knows about his phenomenal physical tools, the excellent size (6'5 244) and rare athletic ability. What few people fail to acknowledge is his success playing through adversity in 2010. As a player that faced heavy scrutiny in the media, Newton had to overcome a lot of distractions to produce the way he did. His ability to improve every week, learn on the fly, and remain focused through turmoil, is encouraging for the team hoping to develop him into a franchise passer.
Currently his mechanics are a little iffy, his footwork is very raw and his throwing mechanics inconsistent in general. Additionally, he is behind the eight-ball in terms of understanding reads, having come from a college spread offense. His talent is undeniable, however. For his size, it is shocking that he can move the way he does and his elusiveness in the pocket is a tremendous asset. He possesses a very strong arm, throws with excellent velocity, and made a number of "wow" throws during his short collegiate career. His accuracy, though often criticized, is better on the field than he is given credit for. It is clear he needs repetition and experience, but he has already made strides in this area. I believe he should be the first overall pick to Carolina and at the worst will not fall past Cincinnati at 4.
Blaine Gabbert, on the other hand, is a prospect I feel has gotten far too much hype in relation to the player he was in college. I see the size and the impressive athleticism. I can acknowledge the guy seems to have a very high football IQ and is great in chalk talk. The word I keep using to describe his draft stock, however, is "manufactured." Never in college was he a dominator or a player that received positive buzz in the media; but upon declaring, many fell all over him. These days I am even hearing him being described as the "safe" pick among Quarterbacks. To me, he has undeniable similarities to former busts: David Carr, Brady Quinn, Alex Smith, and even Joey Harrington. The caveat, of course, is that all of those players were special in college. I think he has the look of a player that will be rushed on to the field at the next level and wind up falling back on bad habits. In college, that bad habit was a lack of comfort and poise in the pocket. My concern is that he will not be mentally tough enough to handle failure and grow as a player. He will surely come off the board in the Top 5, with Buffalo being the best fit at 3; but if you ask me: buyer beware.
ROB: Well, if you've read thus far you can probably tell that I'm not the biggest fan of Gabbert. Not that I think Cam Newton is the best QB prospect I've ever seen either, but I like what he brings to the table a lot more. I think he really loves the game and, although he expresses it in a strange way, really wants to be an icon for the NFL. Newton was scrutinized for telling reporters he wanted to be an "entertainer and an icon" but I think he just wants to be a role model for the NFL, which is an entertainment business. As a prospect, Newton's a lot more accurate than he's given credit for, and he has a very compact throwing motion with freakish athletic ability. His footwork is his only major issue.??Now, I understand the fascination with Gabbert, to a point. When you look at him, he's got everything you look for. He's very smart, with great size, mobility, arm strength and pretty good accuracy. What more could you want, right? Unfortunately he just doesn't look like an NFL QB on tape. A complete lack of pocket presence and inconsistent use of his scrambling ability are very evident. Newton looks much more ready to adapt to the NFL game, as long as he has the necessary work ethic.
6. Which Offensive Tackle in the 2011 class grades out most highly?
RYAN: There are a few that I have closely ranked, but give me Gabe Carimi of Wisconsin. No Offensive Line this past college football season was more formidable than the Badgers', led by the Outland Trophy winner, Carimi. The first thing that stands out when you see him play is his enormous mass (6'7 315) and long arms. Though he could do a better job engaging, he shows good anchor strength and upper body power. He can generate movement in the run game, but he must improve his consistency there. At the Combine and Senior Bowl, he flashed the athleticism to block at the second level and to pass block effectively in the NFL. His feet are pretty light for his size, but he has to improve his reaction to the snap at the next level to handle speedier edge rushers. Teams will love his competitiveness on the field and his work-ethic off it. There is a notion that Carimi may be better off on the right side in the NFL, where he would be less likely to face his opponents' quickest pass-rusher. I would not grade him as an elite prospect by any means, but he should offer value to a team in the 15-25 range. On draft day, I expect him to draw consideration as early as 13 (Detroit) and he should not last beyond the Philadelphia Eagles' pick at 23.
ROB: I have my top two Offensive Tackles, Gabe Carimi and Derek Sherrod, rated extremely similarly (numbers 14 and 17 on my board, respectively). Even though I do have Carimi rated higher overall as a prospect, I think Sherrod definitely has more potential to be the "franchise Left Tackle" that people are always looking for. Sherrod is the prototypical 6'5″ offensive tackle with long arms (35 3/8″) and good athleticism that teams covet. One thing that could hold him back is can he handle the mental aspect of being a LT in the NFL? He gave up on some plays earlier than he should have and needs to sustain his blocks better, but overall I think he will end up being the best Left Tackle from this draft class.


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Morrisville-Eaton School District Superintendent Michael Drahos like to think of himself as an optimistic person but he had difficulty maintaining that persona when he shared his concerns with the members of the Morrisville Lions Club last Thursday evening. Drahos presented a slide show on the effect of recent efforts by Governor Paterson to reduce the budget deficit that the state in currently under. He called his presentation "Impending Financial Challenges facing our learning community" and added that the best he could predict for the district is "somewhere between bad and grim."
Drahos said that the state's crisis is part of a much bigger picture that just Morrisville-Eaton, but that changes being asked of school districts will impact smaller districts more heavily. That is because about 70 percent of the district budget comes from State Aid, a complex formula that determines what a district will receive. Some of the larger school districts receive less than half that amount and can deal with reductions a bit more easily. Just last year the state adopted a more reliable predictor of state assistance called Foundation Aid. That aid for Morrisville-Eaton showed a 12 percent increase over three years. Long term contracts and staffing decisions were based on this amount. To add to the problem, Morrisville-Eaton has experienced an unusually large drop in enrollment. The past year the number of students being taught in district buildings has dropped from 875 to 808. Since part of the state aid formula is based on the number of students, M-E is getting a double dose of bad news.
Currently there are discussions in Albany about freezing or cutting the state aid. To get a sense of the size of that impact on Morrisville-Eaton, Drahos said that a 2 percent decrease in state aide would equal $172,000, almost double the entire local tax levy increase for last school year.
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Knitting Pure and Simple Summer Sweater Patterns - 101 - Tank Top for Women and Ann Norling Patterns - 43 - Checkerboard Shell are both similar patterns: 20 (5 sts. / inch) finished gauge, adult tanks and vests garment, for women, and dk (21-24 sts/4 in) yarn gauge.
You may enjoy taking a look at the Juniper Moon Farm Zooey Natsu Cardigan, Juniper Moon Farm Zooey Garmi Pullover, Juniper Moon Farm Zooey Xiaji Dress, and Juniper Moon Farm Zooey Sommer Tank kits all using Juniper Moon Farm The Summer Collection Patterns.
Hopefully our suggested yarn options for The Summer Collection: Yaz Caplet/Cowl can help you come up with your next exciting new project idea!


text: UPDATED 09:52 15th July 2014 26-year old Chris joined the club in June as Richard Money began preparations for United's return to the Football League, following promotion at the end of last season.Putting pen to paper on a two-year deal, the 6'5' London-born stopper started his career as a youth at Northampton, progressing to make 110 first team appearances for the Cobblers. Chris moved on to Coventry City during the summer of 2011 and stayed for two years before being snapped up by Yeovil in readiness for the Championship campaign of 2013/14 . Chris kept two clean sheets during eight games last season but, now at the Abbey Stadium, he will vie for the no.1 shirt with Will Norris.


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The Health Benefits of Whey
…Whey Whey protein is unique in that it can help the overweight lose excess fat and help the underweight gain pounds in the form of lean muscle. When you drink a whey protein shake in the morning, it's more than just the initial feeling of fullness that suppresses the urge to eat. Whey protein contains…Read More


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1953 GMC 2 Dr 5 Window Pickup Truck5.7L. 4 Speed Automatic Transmission with OD. Fire Engine Red exterior. Custom grey cloth bench seat interior.... More
1972 GMC 1500 Pickup. Nut and bolt restoration with photo documentation. Show condition. Award winner. Rebuilt 350 - 700R4 Transmission - Narrowed Dana 60... More
Carlyle Motors is pleased to offer this gorgeous 1940 GMC Pickup Truck. Fully restored and gorgeous! Highlights of this wonderful truck are listed below: 350... More
Price Reduced for quick sale! Brighton Motorsports is proud to present this 1983 GMC Caballero PU. Very rare GMC version of the popular Chevy El Camino! Finished... More
The GMC Truck nameplate dates back to 1912. Coincidentally, GMC precedes Chevrolet as the original truck brand within the GM lineup. In 1972 GMC used... More
1994 GMC YUKON "SLE" RARE 2-DOOR "4x4" 1500, 5.7 Liter F.I. V8 Automatic/OD, 4x4 on Demand (Floor) New Air Conditioning (Cold)! All Power Options, Tilt, Cruise, Seats, Bose... More
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Police found blood in accused killer's truck
Tip led police tosuspect's truck,detective says
CORPUS CHRISTI - A detective testified Tuesday that an anonymous tip led police to the truck of a man on trial in a fatal gang-related shooting.
Eriberto Mendez's truck had blood on the passenger seat and floorboard when authorities found it in a storage facility, Detective Tim Rivas said. It appeared as though someone had tried to clean the interior, he said.
Mendez, 45, is being tried on charges of murder, aggravated assault and two counts of engaging in organized criminal activity.
He is one of eight men accused in a July 25, 2008, shooting at a home on Segrest Street.
The shooting killed Danny Villarreal, 21, and sent three children to the hospital. Two were hit with shotgun pellets.
Police have said the blood found in the truck belonged to Eduardo Morales, a man who has admitted to being involved in the shooting.
Morales, who is expected to take the stand Wednesday, testified in two previous trials that he was shot during the incident.
He has said Mendez, who also participated in the shooting, dropped him off near a hospital.
Morales pleaded guilty last year in an agreement for a 20-year sentence in exchange for his testimony.
Jesse Garcia, who was accused of ordering the shooting, was convicted in December and sentenced to 55 years in prison.
Garcia's brother-in-law, Humberto Garcia also was convicted last year and sentenced to life in prison for his role in the shooting. Anthony Gonzales, 36, Rudy Castro, 29, Joe Angel Madero, 27, and Jose Olvera, 28, are awaiting trial.
Mendez's trial will resume at 8:30 a.m. Wednesday in 148th District Judge Marisela Saldaña's court.
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I have spent a great deal of time and money on this research. Research involves travel and many expenses.
Some research "things to do" are not done for years, because I do not have the money to do them.
Please Donate Here to support the ongoing research and to keep this website free.
The tradition in our family is that the Flanagans were from Co.Roscommon and moved to Co.Dublin.
Frank Flanagan said there was a story that the Flanagans were stewards to The O'Conor Don at Clonalis House (or Cloonalis), Castlerea, Co.Roscommon. The original house was early 18th century. See [Irish Country Houses].
The old (early 18th century) "Cloonalis House", Co.Roscommon, on 1829 to 1842 map.
There was a story that the Flanagans were stewards to The O'Conor Don here. But there is no evidence to support this yet.
This house is now gone, replaced by the new "Clonalis House" (built 1878) a bit to the N of this site. See 1887 to 1913 map and modern satellite view and street view of entrance.
There was a story that
Flanagan of Tallaght sheltered people in the
1798 Rising.
This is probably confusion with the 1867 rising.
[Frank Flanagan's memoirs]
say his granduncle was a "lieutenant" of the young rebel
Robert Emmet.
He does not say if it is on the Flanagan (would be an older brother of William below) or on the Maguirk side.
Emmet led an abortive rising on 23 July 1803.
After its failure he fled into hiding around Dublin.
He was captured on 25 Aug 1803.
Frank says "My father's uncle was one of Emmet's lieutenants. Major Sirr, the infamous Town Mayor responsible for the capture and death of Lord Edward Fitzgerald, called at my granduncle's home in Rathmines looking for him when he was riding on his way into Dublin to enquire his whereabouts. He was quite civil to his wife and told her to keep her husband out of his clutches as, if he was found, he would certainly be hanged. He was lucky, as when Emmet was captured, his followers broke up."
--- Flanagan,
perhaps from Co.Roscommon,
had issue:
John Flanagan listed at Greenhills, Tallaght, in [Thom's, 1854].


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University of Vermont
Are you excited? Nervous? Ready to go?
Wondering what to expect in your first days and weeks on campus?
You're definitely not alone... hopefully this site will answer your questions, but if we missed something please contact us.
Wondering what it all looks like?
Check out last year's recap video:
Last modified February 19 2015 02:09 PM


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Indeed a huge loss for the researcher fraternity as Dr. Rita Levi-Montalcini died in her home at the age of 103. She is known for her consistent efforts in the field of tracking critical chemical tools, which plays a key role in directing cell growth and build nerve networks.
"I don't use these words easily, but her work revolutionized the study of neural development, from how we think about it to how we intervene", said Dr. Gerald D. Fishbach, a neuroscientist and professor emeritus at Columbia, in response to the death of the lady, who never married.
She has apparently started researching about chicken embryos in the bedroom of her house in Turin, Italy, during World War II, and after years of long reseseazrch, she along with Dr. Stanley Cohen, a biochemist also at Washington University, managed to unleash a protein, which further revealed a lot about disorders of neural growth.
It was in 1986 that she along with Dr. Cohen shared the Nobel Prize in Physiology or Medicine for their contribution in understanding diseases like cancer, Alzheimer's disease etc.
She had even opposed a manifesto barring non-Aryan Italians from having professional careers, and continued with her way of life, thereby showing what she was made up of.
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Cliffs Shaft Mine Museum
The Cliffs Shaft Museum in Ishpeming commemorates an underground iron mine that was in operation on this site for a century, from 1867 to 1967.
One of the fascinating features of the old mine is the enormous monumental air shaft,, designed in the form of an Egyptian obelisk! Now, in the 21st century it's a familiar landmark in Ishpeming, and an easy locator for the Cliffs Shaft Mining Museum which is operated out of several nearby mining structures. Touring the museum also allows visitors to explore a portion of the extensive system of underground tunnels that criss-crossed beneath the surface of this community, and allowed for the excavation of untold millions of tons of valuabe ore - from the first iron mines in this region all the way through the 1950s and 1960s.
The walking tour takes visitors underground into one of the close-to-the-surface shafts; maybe if you are a little claustrophobic you might want to wait out this part. It's clean and well-lit with relatively high clearance, but you still know that you're underground. (The deeper parts of the mine have all been closed off.)
The Mine Museum also includes a large number of "static" displays of mining equipment. My favorite is the enormous dumpster truck that was used to haul rock and slag from the pit. Interestingly, it's been replaced by an even larger "tonka" toy!
- Historical Travel
- Museum Visits
National Ski & Snowboard Hall of Fame & Museum
Now some people might be surprised that the premiere American skiing museum should be located in Michigan. And not, say, in Colorado or Idaho. But think "history," people! Ski-ing in North America originated in the late 19th century with local clubs dedicated to ski jumping and cross-country. The members of those clubs were overwhelmingly Scandinavian immigrants, specifically Norwegians. And now surprisingly, these clubs were concentrated in the Upper Midwest, in the well-known "Lutheran latitudes" stretching across Minnesota and Wisconsin into northern Michigan. The first ski-jumping tournament in North America was held in Hematite in 1904.
All this - and more - I learned at the museum. I learned more about ski jumping, X-country and downhill ski-ing in one hour in Hematite, than I had learned in all the rest of my life up to that point. Actually, I've lived in the area for 17 years now, but I have to admit that I've never been to a single ski-jumping event. Next winter!
(This museum originally just focused upon ski-ing, but due to popular demand, snowboarding has been included within its purview.)
Take the mine tour
Have you ever thought about including a tour of an iron mine on your travel agenda? If so, I can strongly recommend the Tilden Mine Tour. The Tilden operates daily tours in the peak travel season, from June 1 to August 15. This is part of American history and life that not too many people get to see. The mines are the largest non-governmental employer in Marquette County, and they are a real living link to the origins of European settlement throughout the area. This mine is operated by Cleveland Cliffs, a corporation based in Ohio which also owns a number of iron pits in the Mesabi Range of northern Minnesota.
After touring Tilden, you'll understand why our local newspaper is the Marquette Mining Journal.
Currently, the pit at Tilden is more than 2 miles long, and about 1/2 mile wide. The depth of the pit is about 800 feet below the surrounding elevation. Operations remove ore from the earty in the form of solid rock (consisting of about 35% iron), which is then taken to a proceessing plant here on the site. On the tour, you see the enormous grinding and crushing mills which separate out the ore, as well as the concentrating "cobbers" and "cyclones" which shape the ore into marble-size pellets which are then shipped out to steel-makers around the midwest.
Things are big here at the Tilden. If as a child you liked to play with Tonka Trucks, you'll be delighted here: for me, there's something inherently fascinating about Great Big Construction Trucks. Generally, most of the excavators and haulers here are the same of large houses. One of the hauling truck's Firestone tires alone weighs 11,600 pounds, has tread which is 4 1/2 feet wide, stands 13 feet tall, and retails for $30,000.
Awesome Tour of an Iron Ore Mine
The Cliffs Shaft Mine Museum in Ishpeming is open June - October. Walk back in history, via the Ishpeming Historical Society room, to see local historical artifacts representing the local community during the great mining era. View historical displays of miners and mines past and present, headgear & other safety equipment available to miners of yesteryear, and displays on blasting and diamond drilling equipment. Stop in the Ishpeming Rock and Mineral Club's room and view over 500 minerals from the local area, the Upper Peninsula, Midwest and the world. Take a guided tour of the tunnels that the miners walked to the base of the C-Shaft and listen to the history of mining from those who worked the mines. Follow up the stairs past old underground iron ore cars with a stop at the blacksmith shop. Go outside to view towers 97' to 174' high which were used to lower miners 1250' into the bowels of the earth. Stand beside a 170-ton Iron Ore Truck with tires 12 feet high. Don't forget your camera so you can have a memento of your visit standing inside the 30 ton shovel bucket in front of the Dry building or in front of the 170-ton Iron Ore truck. The museum is located at 501 W. Euclid Street, Ishpeming and open Tuesdays through Saturdays from 10 am to 4 pm with a nominal admission.
- Family Travel
- Museum Visits
- Historical Travel
Hiking, Biking, Hunting, Fishing. . .
Ishpeming is an outdoor lover's paradise. Just make sure the land you are on is secure - there are many "cave-in" grounds scattered around, on the sites of former underground mines. But there are plenty of "safe areas" and many interesting paths and parks and recreation areas to explore - especially in the "hilly" areas of West Ishpeming. Actually, many of the hills are slag heaps from disused mines, but many of them have been partially or mostly "reclaimed" by the forces of nature.
- Eco-Tourism
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Originally posted by TheQuantumForcesThatBe
Ok, I have seen many times when it comes to watching videos of people hunting for bigfoot, were they would try to "communicate" with them by banging a stick against a hardy tree. But they do it as if they are hitting a baseball. Correct me(please) if Im wrong here, but I pretend to think that the strongest point of a sound wave would be paralell from the point of the strike. So I would hit on a tree about nine foot off the ground. It would be ear level to the adult bigfoot. Wouldnt they themselfs strike the tree at this hieght if they really exist and are using this method to communicate?? Shrubs can get big in the forest and can easily muffle a sound if its waist high or even chest high! Any thoughts on this?


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A method for identifying the site of an operation during an operation, in particular using a laser system, with the help of unique data about the operation site. A first copy of the unique data is stored in a laser system, the unique data being located in the vicinity of the operation site and/or directly at said operation site. Before the start of the operation, the first copy and the unique data are compared to verify if they are identical and the result of said verification is forwarded to the laser system. In addition a device for identifying an operation site during an operation includes a laser system having a storage unit for storing data and a reading unit configured to determine unique data about the operation site and to provide a first copy of the unique data to the storage unit. The device also includes a comparator device operably connected to the storage device and configured to compare the first copy and the unique data for identity.
1. A method for identifying an operation site during an operation using a laser system, the method comprising:
identifying unique data about the operation site, the unique data being located in an immediate vicinity of the operation site, wherein the operation site is an eye;
performing an identity check between the unique data and a previously stored copy of unique data so as to create a result of the identity check; and
providing the result to the laser system before the operation begins.
2. The method as recited in
3. The method as recited in
4. The method as recited in
5. The method as recited in
6. The method as recited in
7. The method as recited in
8. A device for identifying an operation site for an operation, the device comprising:
a reading unit configured to perform a first scan of a first eye in the operation site prior to the operation to determine a first representative unique characteristic of the first eye as a first characteristic data set, wherein the reading unit is configured to perform a second scan of a patient eye subsequent to the first scan and prior to the operation to determine a second representative unique characteristic of the patient eye as a second characteristic data set;
a shot data acquisition unit configured to determine shot data for correcting a defect of the first eye;
a mixer stage in operative connection with the reading unit and configured to add the first characteristic data set to the shot data so as to form a complete data set;
a storage device in operative connection with the mixer stage and configured to store the complete data;
a comparator device in operative connection to the storage device and the reading unit and configured to compare the first characteristic data set to the second characteristic data set to determine whether identity exists between the patient eye and the first eye;
a laser device in operative connection with the comparator device and configured to perform the operation, wherein the comparator device enables the laser device to perform the operation only when the identity exists.
9. The device as recited in
10. The device as recited in
The present invention relates to a method and a device for identifying an operation site to be treated, in particular an eye, in laser operations.
In laser operations, in particular of an eye, data allowing individual treatment of an eye is required for controlling the laser. This data is usually acquired or determined as patient data; methods such as eyesight testing, refractometer, measuring the topography, for example, of the cornea or of the lens, as well as the aberration of the eye being used for this purpose. This data is stored, whether in a computer-aided manner or manually in a file. Such data includes name, sphere, cylinder, axis, eye (left/right), topography, aberration, etc.
In a later step, this data is entered (sphere, cylinder, axis) or the shot coordinates for the surgical laser are loaded, which were obtained from calculations of topography-aided data or the derivation of coordinates from measurement of the aberrations of the eye. After that, the laser operation is performed based on the data entered.
Thus, the data acquisition and the use of these data sets are separated in space and time. The association between the data and the patient or the individual eye is accomplished using the patient's personal data such as name, first name, date of birth, etc.
Due to the separation in space and time between the acquisition of the data and its use for a laser operation, a connection between the patient's eye at which the data was obtained and the patient's eye on which the operation is to be performed is only given by way of aids. These aids are predominantly the patient's name, the ID number of the physicians' practices, and information on the eye (left or right) from which the data was obtained.
Therefore, this can result in an incorrect association between the data set of the correction and the specific eye under operation. This may be due to the system software used for maintaining the data sets, or else to human failure. In particular, the right and left eyes of the same patient can easily be confused, even when acting in the most careful manner during data acquisition. Confusion of patients with each other (similarity of names, inattentiveness during data acquisition, etc.) is also possible.
An object of the present invention is to provide a method and a device for identifying an operation site, in particular an eye, during a laser operation, which prevent the risk of operations of the wrong operation site or eye.
The present invention provides a method for identifying an operation site during an operation, in particular using a laser system, with the help of unique data about the operation site, a first copy of the unique data being stored in the laser system, the unique data being located in the immediate vicinity of the operation site and/or at the operation site, the first copy and the unique data being checked for their identity before the operation begins, and the result of the identity check being passed on to the laser system. This enables the individual operation site, mainly the eye, to be uniquely identified as the correct one for which the shot positions are provided in the laser. In this way, it is prevented that a patient is treated with incorrect shot data and, thus, that corrections, for example, of his/her eye are made that were calculated for a different patient.
Laser systems are understood to mean surgical systems having a laser, for example, an excimer laser such as a spot scanning excimer laser. Preferably, these laser systems also include computers to carry out the treatment in a computer-aided manner. Particularly preferably, accessory systems such as eye-tracking systems are also provided, as well as lighting devices for the operation site, i.e., especially for the eye.
The unique data is unique with respect to the operation site. Therefore, it is possible for an operation site to be uniquely distinguished from another operation site on the basis of this unique data.
The first copy of the unique data is a copy of the relevant data content that uniquely identifies the eye. This first copy can be stored in the laser system and is thus available to the laser system in the later course of the operation. This unique data is particularly preferably determined prior to the operation and is then available in the further course of the operation.
The unique data is particularly preferably located in the immediate vicinity of the operation site and/or at the operation site. Therefore, it is particularly preferred for this unique data to be immediately next to the eye or even in the eye. The data here can preferably be additionally attached data or data that is already available directly in the operation site or eye. Thus, for example, it is possible for this unique data to be spatially and temporally bound to the eye in a fixed manner, for example, using a sticker, a color marking, preferably as a bar code, a microchip firmly connected to the eyebrow, etc., or the unique data is data that is already located at the operation site, i.e., fixed parameters which uniquely define this operation site, in particular the eye, such as a fingerprint defines a thumb.
Preferably, the first copy of the unique data is then compared to the unique data before the operation begins, thus performing an identity check. Then, the result of this identity check is preferably passed on to the laser system. The further procedure can then be made dependent on the result of this identity check. Thus, for example, it is possible not to permit the operation at all unless the identity check has been completed successfully. Moreover, it is conceivable to inform the operator of a failed identity check before the operation begins.
According to a preferred exemplary embodiment of the present invention, the unique data includes the patient's name, the patient's first name, the patient's data of birth, patient ID, physician ID, information about the operation site, or a combination of individual pieces or all of this data. Thus, for example, it is possible to generate a character string containing information about the specific eye of a specific patient, thus making this eye unique. However, it is particularly preferred to use information about the operation site itself, in particular, vessel patterns and/or patterns of the iris. For this purpose, it is particularly preferred to use vessel patterns of the fundus of the eye, which are different for each eye, even of the same patient, and which have the most individual characteristics uniquely identifying the eye. The pattern of the iris is particularly preferred as well. These patterns are unique as well as stable in time and space. This information about the eye has the further advantage that many laser systems already contain measuring devices with possibilities to record images as well as image-processing components (topography devices, aberrometers, etc.). Thus, the characteristic or the unique data can be determined and stored with the data set particularly preferably concurrently with the data acquisition. On the side of the operation device, image-processing systems (eye-tracking systems) are frequently used as well. Using these systems, it is now possible for the characteristic or the unique data to be determined from the eye currently present for the operation and to be compared to the characteristic in the data set. If the characteristic is identical, then the unique association is given.
In particularly preferred exemplary embodiments of the present invention, the unique data is embodied as a bar code, microchip, character strings, or a combination of these types of representation. This unique data, which is then preferably arranged in the immediate vicinity of the operation site can, for example, be stuck, drawn, applied, or painted on.
Moreover, the present invention is achieved by a device for identifying an operation site during an operation, particularly preferrably for carrying out one of the methods according to the present invention, containing a laser system having a storage unit with a storage of unique data about the operation site and a laser unit, the unique data being determinable using the laser unit, a first copy of the unique data being storable in the storage unit, and provision being made for a comparator device which allows the first copy and the unique data to be checked for their identity. Using such a device, it is possible both to acquire unique data using a laser unit, such as a bar code laser or an image sensing unit, and to store this unique data in the form of a copy in the storage unit so that it can later be checked with the unique data using a comparator device.
This device guarantees that the obtained data is always uniquely associated with the eye from which it was obtained.
Confusion of names, etc., no longer matter because, primarily, the data is always linked to eye and not to the name. Moreover, these solutions can preferably be used actively or passively.
In the case of passive use, the data set is selected as before using patient names, etc.; immediately thereafter, the laser unit or an identification unit looks for the characteristic or the unique data at the eye and compares it to the data set. In case of discrepancy between the characteristics, operation is not permitted.
In the case of active use, the patient's eye is examined directly using the laser unit or the identification unit, and the matching data set is automatically loaded into the laser. Preferably, this patient data (such as name, etc.) is then also indicated to the physician.
Moreover, it is possible to use the present invention such that it includes attachment of the unique data or of this additional characteristic, or to obtain this unique data directly from the eye itself.
It is particularly preferred to recheck the eye correction state shortly before the operation. In this manner, it is in addition possible to prevent double operations of the same eye.
In the following, advantageous refinements of the present invention are described with reference to drawings, in which
Later, in a second step II, the specific eye 5′ which is present for the operation and has the unique characteristic 10′ of the iris pattern is scanned, and unique characteristic 10′ is determined in identification unit 40′. In storage device 45, the shot data appropriate for the characteristic is then either loaded into storage unit 45 on the basis of the previously stored shot data and/or this data is transferred to storage unit 45 through direct entry of the data, such as sphere, aberration, etc., by the physician. Then, characteristic 10′ determined from the specific eye 5′ located in front of the laser and characteristic 10, which is available in storage device 45 and which was previously determined for the present shot data set in step I are compared in comparator device 49. If the two characteristics 10 and 10′ match, comparator device 49 outputs a signal enabling operation OP.
In this manner, the association with the shot data present for the operation is verified on the basis of the unique data or characteristic 10′ present in or at eye 5′, thus providing exceptional safety from confusions or misassociations during the subsequent operation.
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Sports Fitness CRE Loaded Template 18169
CRE Loaded Template that was composed by our webmaster artist Modlin.
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Sporting goods store template with a blue and white color scheme and sort of snowy theme. There is a white shoe featured in the header under a black and blue logo you can customize. There are three columns of light gray and white backgrounds with black text and blue accents. The template has various sporting goods and fitness equipment on display. Sports Fitness CRE Loaded Template 18169 is available in the following sources: .PSD, and .PHP. Software required includes Winzip 9+ (Windows) or Stuffit Expander 10+ (Mac) for uncompressing .zip files, Adobe Photoshop CS+, Hosting with PHP4x and MySQL4x, Adobe Dreamweaver 8+ (or any php-editor), Apache Only (on Unix/Freebsd/Linux/Windows), and CRE Loaded 6.2[10+] Standard and. It has had a total of total of 4 downloads since it first appeared.


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Originally written on 60 Max Power O | Last updated 12/27/12
Richard Sherman said all along that he would win his case against the NFL for a PED violation. On Thursday, Sherman told NFL.com's Steve Wyche that he is free to play and will not be suspended. The NFL responded with the following statement on the Sherman news: We are reviewing the decision, but decline comment at this time due to the confidentiality provision of the program. If this decision had come earlier, it has been speculated that Sherman could have been selected to the Pro-Bowl, but the lingering appeal seemed to sway some votes. var switchTo5x=true; stLight.options({publisher:''});
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General Banter / Re: Happy Birthday to...« on: December 06, 2011, 08:42:34 am »
Today is also G-Money's birfenday...
This section allows you to view all posts made by this member. Note that you can only see posts made in areas you currently have access to.
4 / leather / brown / "Bad Mother F*cker"
all innova sponsored players: glow league every tuesday (weather permitting, last week was an extremely wet exception), $5 per player, random draw doubles, best shot.
Didnt Tank win,#1?


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1799 1C --Damaged--ANACS. VG8 Details....
2008 February Long Beach, CA Signature Coin Auction #460
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Important 1799 S-189 Cent Rarity, VG8 Details1799 1C --Damaged--ANACS. VG8 Details. S-189, B-3, R.2. Both sides are moderately corroded, and covered with fine old scratches that undoubtedly represent an attempt to remove or diminish the corrosion. It appears that the process occurred a long time ago. We are still certain that any interested bidder will find certain redeeming qualities, as we do ourselves. EAC 3. (Variety PCGS# 36140, Base PCGS# 1443)
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Rasmussen Special Edition Catalog
This hard bound volume contains the magnificent Wes Rasmussen Large Cent Collection, formed by a former President of the Early American Coppers society which was auctioned at the 2005 Florida United Numismatic Auction. Reserve your copy of this remarkable volume for just $75 today.
Rasmussen Signed Limited Edition Catalog
A hard bound limited library edition of the Wes Rasmussen Collection Catalog, signed by Wes Rasmussen, Mark Borckardt, Greg Rohan, and Denis Loring, is available while supplies last. Only 100 produced. Reserve your copy of this remarkable limited edition signed volume for just $150 today.
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Book your room at Hotel Roc Linda
Standard Twin RoomMax Occupancy: 3 guests (up to 2 children, 1 infant)
Standard Double Single UseMax Occupancy: 2 guests
Get an overview of this hotel3-star Playa de Palma hotel in Can Pastilla with restaurant
Collect 200 points
Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.*Offers may apply
Located in Can Pastilla, this hotel is 0.6 mi (0.9 km) from Palma Aquarium and within 9 mi (15 km) of Mallorca Cathedral and Bellver Castle. Basilica of St. Francis and Parc de La Mar are also within 9 mi (15 km).
Hotel Features
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Additionally, a poolside bar, self parking, and a children's pool are onsite.
Room Amenities
All 189 rooms offer satellite TV, safes, and phones.Information missing or incorrect? Tell us!
Hotel Amenities
Hotel Amenities
Hotel Roc Linda features an outdoor pool and a children's pool. The hotel offers a restaurant. Guests can unwind with a drink at one of the hotel's bars, which include a poolside bar and a bar/lounge.
This Playa de Palma hotel also offers multilingual staff, beach/pool umbrellas, and an elevator (lift). Onsite parking is available (surcharge).
Hotel Roc Linda has designated areas for smoking.
- Beach umbrellas
- Beach sun loungers
- Pool sun loungers
- Total number of rooms - 189
- Number of floors - 5
- Designated smoking areas
- Pool umbrellas
- Poolside bar
- Children's pool
- Breakfast available (surcharge)
- Multilingual staff
- 24-hour front desk
- Tennis on site
- Bar/lounge
- Elevator/lift
- Restaurant
- Self parking (surcharge)
- Outdoor pool
Self parking (surcharge)
Room Amenities
- Air conditioning
- Phone
- Daily housekeeping
- In-room safe
- Satellite TV service
- Cribs/infant beds available
Where to Eat
Hotel Roc Linda has a restaurant serving breakfast only.
Nearby Things to Do
An outdoor pool and a children's pool are on site.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Personal motorized watercraft on site
- Windsurfing nearby
- Water skiing nearby
- Bicycle rentals nearby
- Parasailing nearby
Hotel Policies
Payment types
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- Fee for in-room wireless Internet: EUR 6 per day (rates may vary)
- Fee for high-speed Internet (wired) in public areas: EUR 2 (for 30 minutes, rates may vary)
- In-room safe fee: EUR 3 per day
We should mention
Cash transactions at this property cannot exceed EUR 2500, due to national regulations. For further details, please contact the property using information in the booking confirmation.


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Bank of China Profit Growth Slows After Loan Demand Eases
April 27 (Bloomberg) -- Bank of China Ltd., the country's third-biggest lender by assets, said profit growth decelerated to 10 percent in the first quarter as the world's second-largest economy slowed, curtailing loan expansion and margins.
Net income climbed to 36.8 billion yuan ($5.8 billion) from 33.4 billion yuan a year earlier, according to stock exchange filings by the Beijing-based lender yesterday. Profit compared with the 37.5 billion-yuan average estimate of 10 analysts surveyed by Bloomberg.
China's economy expanded at the slowest pace in almost three years last quarter, increasing pressure on Premier Wen Jiabao to ease monetary policy. The central bank in February reduced lenders' reserve requirements for the second time in three months to spur credit expansion and bolster economic growth without triggering gains in consumer and property prices.
"Profit growth at Bank of China slowed because of the country's macroeconomic environment," said Lewis Wan, who oversees $250 million in assets as chief investment officer at Pride Investments Group Ltd. "If China loosens its monetary policy, loan growth may pick up in the second half and bolster Chinese banks' revenues."
Shares in the lender have gained 47 percent in Hong Kong trading since a 2 1/2-year low on Oct. 4, on speculation that economic growth may accelerate as officials begin easing monetary policy. Bank of China fell 0.6 percent to HK$3.22 as of 10 a.m., compared with a 0.5 percent increase in the city's benchmark Hang Seng Index.
Slower Loan Growth
Bank of China advanced 247 billion yuan of new loans in the first quarter, 17 percent less than a year earlier, according to yesterday's statement. Profit growth declined from 10.8 percent in the previous quarter and 28 percent a year earlier.
Net interest income rose 13.2 percent to 60.6 billion yuan during the quarter while the loan margin stayed unchanged at 2.11 percent. Net fee and commission income, from businesses such as trade finance and custodial services, gained 13.8 percent to 21.2 billion yuan.
Premier Wen is trying to spur lending to smaller companies while restricting home loans that may inflate a property bubble. The risk of lending to real estate developers is growing as residential prices fall, Liu Mingkang, former chairman of the banking regulator, said last week.
Bank of China's non-performing loans, or those overdue for at least three months, rose by 665 million yuan to 63.9 billion yuan at the end of March, and amounted to 0.97 percent of total loans.
'Soft Landing'
Moody's Investors Service on April 12 kept its "stable" outlook on Chinese banks, saying a "soft landing" of the economy will allow them to maintain profitability and manage what may be a gradual rise in non-performing loans. Economists at Nomura Holdings Inc., Deutsche Bank AG and Morgan Stanley last month increased their economic-growth forecasts for 2012.
Bank of China's capital adequacy ratio narrowed in the quarter to 12.8 percent as of March 31 from 12.97 percent at the beginning of the year. The banking regulator said in August it will require the nation's most important lenders to have a minimum ratio of 11.5 percent by the end of 2013. The core capital adequacy ratio stood at 9.97 percent.
'Fundraising Pressure'
The bank "is likely to face higher fundraising pressure as its capital adequacy ratio declined," Wan of Pride Investments said.
Bank of China was the only lender from the nation to be included on a provisional list of 29 systemically important financial institutions published by the Financial Stability Board, a body set up by the Group of 20 nations, in November. The global banks must hold additional capital buffers ranging from 1 to 2.5 percentage points under those plans.
Smaller rival China Minsheng Banking Corp., the nation's first non-state lender, yesterday said its first-quarter net income rose 48 percent to 9.2 billion yuan. That beat the 8.5 billion-yuan average forecast in a Bloomberg News survey of nine analysts. Non-performing loans stood at 0.67 percent of total credit as of March 31.
To contact the reporter on this story: Stephanie Tong in Hong Kong at email@example.com
To contact the editor responsible for this story: Chitra Somayaji at firstname.lastname@example.com


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Britt Hayes
Britt Hayes is a writer, movie lover, and sensible sweater enthusiast living in Austin, Texas. She watches too much TV and never eats her vegetables. Her mom is worried about her.
While you're sitting around the Thanksgiving dinner table with your family next week, we're not sure whether or not you'll want to thank MGM for this bit of news: the studio is remaking 'Road House,' the 80s classic starring Patrick Swayze and Kelly Lynch, with director Rob Cohen -- a name you'll recognize as the director of the first 'Fast and Furious' movie, as well as the Vin Diesel action vehicle 'xXx.' It could be worse?
Well this is interesting -- and not in a great way. 'Zero Dark Thirty' and 'Contagion' star Jennifer Ehle has been cast in the upcoming adaptation of mommy porn favorite '50 Shades of Grey.' No, she won't be grabbing a whip. The actress will be playing the role of Anastasia Steele's mother, who should be very concerned about what her daughter is doing.
Thanks to the millions of people who tuned into, tweeted, and confused their moms on Facebook about 'Sharknado,' SyFy is continuing to ride the shark schlock horror wave with 'Avalanche Sharks,' which is exactly what it sounds like. But in case you need more of an explanation, you can watch this trailer for the upcoming "film," which continues SyFy's tradition of featuring purposely bad movies for those who find actual movies to be just a bit too demanding of their intellectual faculties.
At long last, our national nightmare is over: Universal and Focus Features have found their leads for the upcoming adaptation of '50 Shades of Grey.' Dakota Johnson of 'The Social Network' has been cast as Anastasia Steele, the college student who enters into a dominant/submissive relationship with enigmatic businessman Christian Grey because fairy tales do come true, or something. Charlie Hunnam of 'Pacific Rim' and 'Sons of Anarchy' will play Christian.
'Glee' star Cory Monteith has passed away at the age of 31 in Vancouver, Canada, due to unspecified causes.
Warner Bros. has decided it's smart (and smarter) to ditch Bobby and Peter Farrelly's 'Dumb and Dumber 2', forcing the brothers to shop the sequel around to other studios.
When you think of Easter eggs in the context of movies and television, you think of seeing stuff like the pizza delivery truck in all the Pixar movies, or J.J. Abrams using the faux slushie brand Slusho in each of his movies
Are you ready to see Bill Hader greased up and sporing tiny red shorts? We are! The 'SNL' star has signed on to take the lead role in the upcoming 'Baywatch' film.
February is the month of Valentine's Day, and there's nothing we love more than new movies in the theater. Check out our guide to the films hitting the big screen in February.
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FLORHAM PARK, N.J. (AP) -- New York Jets wide receiver Plaxico Burress is questionable for the team's game at Buffalo on Sunday with a sore lower back.
Defensive linemen Mike DeVito (knee) and Kenrick Ellis (left ankle), and defensive back Isaiah Trufant (hamstring) were also limited at practice Friday and listed as questionable. Coach Rex Ryan says if the game against the Bills were Friday, it's likely neither DeVito nor Ellis would play.
Burress, added to the injury report Thursday, still has soreness -- something he has experienced at times throughout the season but hadn't previously been limited by it. Ryan says he thinks he'll be fine, "but sometimes those backs are troublesome. Hopefully he's feeling good when we play on Sunday." Burress is coming off a three-touchdown performance against San Diego before the bye.


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Where is Budapest Hungary
Where is Budapest Hungary
Where is Budapest Hungary ?
The Chain bridge – perhaps the most obvious symbol of Budapest, designed by William Thierney Clark, execution manager Adam Clark, they are not brothers, the designer was an English the execution manager is a Scottish gentleman. The distance between the two main pillars is 202m.
This bridge was the first bridge on the Danube in the whole Hungarian area. It is interesting the Danube has 417 km section in Hungary. Clark designed three bridges for Istvan Szechenyi and Gyorgy Sina, but only one was built. The price of the bridge was 13 times of the National Museum which was built at the same time. The location of the bridge was chosed by William Thierney Clark as well.
The bridge on the picture is not the original Chain bridge, the original bridge was blowed up in the II World War by the escaping German Army. The new bridge was opened at the 100th anniverary of the old bridge (1949).
Where is Budapest Hungary
Budapest is located in the Northern hemisphere, in Middle Eastern Europe in the middle of Austria, Croatia, Romaine, Serbie, Slovakia, Slovenia and Ukraine, not very far from Italy or Germany. See the map below. Budapest is located 217km (134 miles) from Vienna, 689km(428 Miles) from Berlin, 1247km (775 Miles) from Paris, 1450 km (901 miles) from London, 1565km (972 miles) from Moscow, 2200km (1367 miles) from Cairo, 5354km (3327 miles) from Delhi, 7005km (4352 miles) from New York, 9046km(4841 miles) from Beijing, 9040km (5617 Miles) from Tokio, 9046km (5621 miles) from Cape town, 9986km (6205 miles) from Rio de Janeiro, 9992km(6208 miles) from Los Angeles, 15770km (9800 miles) from Sydney. All distance is as the crow flies, the distance on the road is longer.
Distance from European cities nearby
The Distance between Budapest and Vienna is 243km, the distance between Prague and Budapest is 525km. The distance between Budapest and Bratislava is 200km, Ljubljana Budapest distance is 462 km, Zagreb Budapest distance is 345 km, mostly on motorways. So Bratislava, Vienna, Zagreb, Ljubljana are the closest capital cities nearby.
Where is Budapest inside Hungary
Budapest is located in the Middle North part of Hungary, near to Slovakian border, little bit West from the center of Hungary. This part of Hungary is part of the Wonderful 60km long Danube bend area.
Budapest view from Gellert hill
Budapest view from the Gellert hill, the Danube is in the middle, at the left side of the Danube is the Castle district with the National Gallery and Mathias church, Buda hills in the background. Budapest the capital of Hungary is one of the most popular tourist targets in Europe. Approximately Four million tourists visit Budapest every year. Budapest is the 25th most popular tourist destination in the whole World. The city is very romantic with lots of picturesque places all around. The Danube crosses the city and beautiful forested mountains and islands can be found here. Up in Buda side the World heritage Castle district can be found, which was a place for Weddings of the Kings.
The Gellert hill which is located next to the Danube is a very popular place for picnic, and there is a playground also can be found there. At the top of the hill, the Citadel and the Sculpture can be checked together with several canons, restaurant, and beautiful view on the city.
The Heroes square is located in front of the Varosliget City park, but there are many other attractions can be found there: the Vajdahunyad romantic Castle which is mixture of different buildings, the Zoo, the Circus, the Ice skating ring, the beautiful green park with the Lake.
Budapest has a long history
Few places has such a long and interesting history as Budapest has. From the Roman era through Hungarian invasion (896) to the Carpathian basin, Tatarian invasion in 13th century (1240-42) after the and Turkish invasion in the 16th century (1540-1686) through the first and second world war, nazis, communism to capitalism. There are ruins of the Roman era called Aquincum, which was the name of the city at that time.
The ruins can be seen scattered relatively in huge area of the city. This part of the city called Obuda. (Ancient Buda). In the famous Obuda island, which is a scene of the popular summer music festival, they found the traces of the Palace of the Roman emperor Hadrianus, when they construct the boat factory at the North part of the island in the 50's.
Aquincum was founded around 89 AD. Seems it was much smaller than the recent area of the city. It was a military camp according to historians.
Budapest is packed with older buildings. Some of the bigger residential building's basements surves as a refuge in the World War. Some of this basements has an area of the soccer field (60*120m). In the Castle district there is a unique Hospital in the Rock, which was a Hospital during the War.
There are some buildings from the era of the Turkish invasion as well (1540-1686). There are three Turkish baths in Budapest, and the Tomb of Gul baba, which is still a pilgrimage place in Budapest.
This city has seen lots of history. Some bullets in the walls of the city can still be seen in several places. Budapest has nearly hundred museums of all kind. See in detail at below link.
There are Roman era ruins several places at the North Buda area, scattered around, there is a bath, several columns, walls in different places but mostly at Obuda area, and in the Obuda island they also found traces in the past. This area was called Aquincum and it was part of the Pannonia province.
Budapest Hungary's capital is the city of social life
Budapest famous for their social life. Lots of conferences, company parties held here. The restaurants, cafes, ruin pubs, tee houses, wine bars are usually packed with people, especially in the inner city.
The most tea houses can be found in the Liszt Ferenc square not far from Nyugati railways station. Places next to the Danube, has excellent view and atmosphere, but usually these are the most expensive, premium locations. Hungarians usually very polite and helpful with foreign people. Budapest is also very kid-friendly, see program possibilities below:
Budapest the city of Thermal water
Budapest is famous about it's thermal water. Several spas can be found here, some from the Turkish era in the 16th century. Budapest is incredibly rich in Thermal water, there is a huge quantity of thermal water here. For example the heating of the Zoo and Plant garden is also made by thermal water of the Szechenyi baths. There are many medicinal baths, and bigger open baths available here, some of them with huge pools, for thousands of people.
The biggest thermal bath is the Szechenyi bath in the city park, the most popular open bath is the Palatinus in the Margaret island. The Szechenyi is open in the whole year until 10 o'clock in the evening. The Szechenyi has 18 pools, 15 covered and three external pools, while the Palatinus has 11 pool, included a huge wave pool and slides as well, but it is only open between Spring and Autumn, depending on weather conditions as well.
See detail of Budapest baths, and open beaches in detail at below links.
Budapest is the city of fun
All kinds of fun available here from the beautiful parks, islands, spas, open beaches till all kinds of sports, boat rides, cave visits, Castle visits, mountain hiking, water sports, horse riding and hard to name all the possibilities easily provided here. Budapest has a zoo, romantic castle, beautiful lakes, very nice food and wine. All kinds of fancy staff life shooting with real guns, water slides, Go-kart fields, ruin pubs can be find here.
There are many games available in the city designed especially for tourists, like finding out how to escape from a room, learning the Hungarian language, which is pretty difficult and perhaps funny as well for tourists, team games, and other fun stuffs.
There are many bus rides available, one of them even manage to go in the water, the same bus which goes in the streets of the city, see the picture below. The bus starts at the land after go in the water and after returns to the land as well.
At the border areas of the city there are many beautiful areas, and nature reserves as well, like the one at the picture at South Buda area. The downside of this place for example that there are many mosquitos there, I made this picture and after was defeated badly, so we quickly leave the area. For a one day stay perhaps not so interesting to travel so much.
Budapest caves
In Budapest there are several caves can be found. The most known and popular are the Palvolgyi and Szemlohegyi caves. Both can be found in North Buda area near Szepvolgyi (Beautiful valley) street, at the bottom of Buda hills. The Palvolgyi is a stalactite cave, which is incredible long. The paved and lit up visitor area is 400m, but goes up and down. Some warm clothes is needed even in summer because the temperature is usually 12 Celsius. A good pair of shoes is also useful, even the visitor area is fully paved with concrete stairs and lighted up as well.
Budapest is the city of music
Budapest is a well known city of music. Lots of people know about the famous Sziget festival which attracts 380,000 visitors every year, or the nowadays state of the art Classical music center the Halls of Art. Budapest has a well known Opera and several other places for musical events. Open air discos are also very popular here. See concerts at below link:
Budapest is a good city for shopping.
Budapest has lots of traditional markets, newest shopping malls, smaller and bigger ones, many web stores and lots of other possibilities. There are many stores with different goods, some of them cheaper others are really expensive. The most expensive places are the Vaczi utca pedestrian street in the inner city, the Castle district and the inner districts. Usually Buda is more expensive than Pest. Even if you don't intend to buy anything the Vaczi utca (street) in the inner city is a good place to stroll around.
There are about a dozen shopping mall here, some of them are really big, around 100,000 m2 of retail area, or even bigger, on several level, with a huge underground parking. There are many cheaper shops as well, and many used clothes for really cheap price and other stuff. Most stores accomodate to the Hungarian market regarding prices and demand, so cannot expect the same level or quality than in London or other similar cities. Which are the most interesting Hungarian products ? The Tokaj Aszu dessert wine, the Paprika from Szeged, porcelain from Herend, Zsolnay porcelain at Pecs or porcelain from Holloko.
Budapest islands
Perhaps it sound not so common, but there are several islands in Budapest. The two biggest is the Csepel island at South and the Szentendrei island at North. The area of the Csepel island is 257 km2, it is 48km long and 7-8 km wide. It is located between the Danube and the Soroksari Danube branch.
The Szentendre island is located at the North part of Budapest. It is a 56km2 are 31 km long island. From Budapest cannot be accessed.
Budapest wildlife
Budapest is an interesting city. Even if it is a metropolis with 1.7 million people, the location is unique here with the hills, rivers, islands and parks. Many interesting animal or bird can appear in the city. The usual common residents are the crows, which can spend their lives in several m2 in a park. They manange to get the chips out of the garbage, and check if any left in. Woodpeckers are also quite common, like Green woodpecker, or Great spotted woodpeckers. Sometimes very interesting species can appear like Eagle Owl, Peregrine Falcon, Ruddy shelduck or Waxwings. Animals like Beech marten, Red fox, birds like Common Kestrel, Buzzard, Little Grebe, Great Crested Grebe, Golden oriole, Owls, Grey heron, Kingfisher are quite common in certain areas. In Spring or Fall migration very interesting species can occur, such as Nightjar, Crane, many kinds of gulls, water birds or singing birds. In the Budapest parks singing birds like Robin, Nightingale, Great and Blue tits, Warblers, Black birds, Wren are quite common. On the Danube Great Cormorants, Gulls, different types of Ducks in winter can occur.
Places to visit near Budapest
The vicinity of Budapest is packed with very nice locations. The one I recommend the most is the Szentendre, Visegrad, Esztergom line in the famous Danube bend North from Budapest. All three cities can be found in the same direction.
is a smaller town with picturesque looking narrow streets, Danube bank, lots of museums, and nice restaurants.
is the finest place here with several Castles, beautiful nature, and friendly atmosphere.
is where the biggest 100m high temple found in all Hungary.
It doesn't stop there in Godollo the Castle of the former princess Elisabeth or Sissy can be found, in Alcsut a very nice arboretum can be found. Next to the Danube Vac is also a nice place, and all the settlements in the Danube bend as well.
The Pilis hills
are also very popular with crystal clear air, and a ski course. The Ram spring valley canyon is very popular for hiking.
Thanks for reading !


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A bond hearing for former Coastal Carolina Fair president Dennis Lott was postponed Saturday so that he could undergo a mental evaluation, officials said.
Lott, 57, of Goose Creek, was arrested Friday night by Walterboro Police, accused of stealing nearly $200,000 from the fair.
He was transported to the Cannon Detention Center after failing to surrender to Charleston County sheriff's deputies on a breach of trust charge.
Charleston County Sheriff's Maj. Eric Watson said Lott will appear in bond court after completing a mental evaluation. It was not immediately clear on Saturday when a hearing would likely occur.
An investigation into the missing funds is ongoing.
Sheriff's deputies were notified Thursday about the alleged theft from the fair's accounts.
An incident report identified Lott, last year's fair president, a volunteer position, as a suspect in the embezzlement case. Lott held the position for two years.
In a press conference on Friday, authorities said that the money was discovered missing after a forensic audit conducted by the Exchange Club of Charleston, which runs the fair, uncovered a single check Lott wrote to himself in July and signed for $190,000.
When contacted by The Post and Courier early Friday, Lott would only say he believed the situation would be resolved soon.
According to Berkeley County court records, a foreclosure complaint was filed against Lott in May, about two months before the theft is believed to have occurred. The home in the Crowfield Plantation subdivision was sold in July, court records show.
Lott would not comment on whether the alleged theft and his home's foreclosure were connected.
Reach Christina Elmore at 937-5908 or at Twitter.com/celmorePC.
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Glacier Gardens Rainforest Adventure
Alaska, United States
Discover a botanical garden paradise nestled in the midst of the mighty Tongass Rainforest. Guided tours aboard easily accessible shuttles escort you through beautifully designed landscapes and into the heart of the Alaskan temperate rainforest where you will learn all about this fascinating environment. Breathtaking scenic views of Juneau and the Mendenhall Valley wait 580ft atop Thunder Mountain. Look into an active American Bald Eagles nest from our Visitor's Center atrium adorned with captivating hanging gardens and floral delights unlike any you have ever seen. A complete garden gift shop and cafe is located in our atrium for your enjoyment. Open 9am-6pm daily May 1- September 30
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