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While I would have loved to have seen these completed with a navy sole, the Zoom Huarache Trainer Low "The Show" Quickstrike is still very nice. Summer, shorts and Huaraches all work well together. Plus, I love it when the Oregon design gang goes all out on details, even the ones that go unseen when worn such as the insoles. "For the second consecutive year, Minnesota Twins perennial All-Star, Joe Mauer is the cover athlete for MLB® 11 The Show, available exclusively for PlayStation®. To commemorate this achievement, Nike will release the Nike Huarache TR Low "The Show". This very limited trainer will be released on April 9th at Nike Mall of America, EastBay and select Minnesota and Chicagoland retailers. "The Huarache TR Low "The Show" retails for $110 and is a baseball lover and gamers' dream. Baseball inspired stitching around the toe emulates that of laces on a ball. The PlayStation logo is prominently displayed on the shoe's outer tongue. The game's cover artwork, including the image of Mauer and the MLB® The Show classic logo, embellish the inner sock liners of both the left and right shoe respectively. The right shoe's inner tongue includes Mauer's iconic '7M' logo. "While style certainly catches the eye, the Nike Huarache Low silhouette is a premier training shoe designed for maximum support and traction. Mauer's signature shoe is designed to fit like a glove for a custom feel to help you perform like a pro." Set to launch April 9th at NikeStore.com and select retailers.
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Some are speculating that Britney Spears and Iggy Azalea may not be on the best terms despite their recent collaboration on the single "Pretty Girls."
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Why Hasn't Sen. Elizabeth Warren Backed the Iran Deal?
Robert Naiman | Posted 02.04.2014 | Politics
Read More: Aipac, Iran Nuclear Deal, Elizabeth Warren, Cnn, Dick Durbin, Dianne Feinstein, Noam Neusner, Carl Levin, M.J. Rosenberg, Politics News
Given that neocons are agitating for new Congressional sanctions on Iran now in the hopes that this will sink diplomacy, shouldn't Senator Warren be speaking out now?
Washington Spectator correspondent Wayne Barrett investigates Mitt Romney's saber-rattling advisor Dan Senor--and his disastrous record in Iraq. The...


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In Praise of Dissimilarity
Magazine: Summer 2011
- Opinion & Analysis
- Read Time: 9 min
Products and markets with nothing in common "taxonomically" can have "thematic similarity," which may open up important business opportunities.
Showing 21-39 of 39
Products and markets with nothing in common "taxonomically" can have "thematic similarity," which may open up important business opportunities.
Universities can be major resources in a company's innovation strategy. But to extract the most business value from research, companies need to follow seven rules.
Service businesses that collaborate with many organizations tend to be less innovative — and less profitable — than those that work with a smaller number of partners.
How has Microsoft adapted to the era of open source? A new book, Burning the Ships: Intellectual Property and the Transformation of Microsoft, gives a detailed view into that question.
"Political influence may come at the cost of lower productivity," explains Anders Olofsgård, a senior fellow at the Stockholm Institute of Transition Economics at the Stockholm School of Economics. "Politicians are expecting something in return from you. One way to pay back politicians is through jobs. So you may be locked into keeping higher employment than you otherwise might be." Olofsgård and co-author Raj M. Desai, a visiting fellow at the Brookings Institution, argue that bloated staffs are no bargain for any company.
Relationships with academic institution scan play an important role in continuing to generate new value for shareholders if you know how to approach those relationships.
The very factors that make partnerships with customers or suppliers beneficial can leave those relationships vulnerable to deterioration.
Reverse auctions can save money and create better relationships with suppliers. But there also can be a backlash.
Research shows that the most successful strategic alliances are in companies that have a dedicated function specifically assigned to oversee alliances. Such companies more readily solve problems related to the four key alliance-management elements — knowledge management, external visibility, internal coordination and accountability.
Effective supply-chain management requires choosing a type of relationship appropriate to product and market conditions and adapting management practices to that relationship.
Processes to solidify and streamline supplier-customer relationships can result in mutually beneficial commercial success.
Showing 21-39 of 39


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Seven Stories Press | Jan 04, 2011
Seven Stories Press
| Jun 07, 2005
| 192 Pages
| 5-1/2 x 8-1/4
Seven Stories Press
| Jan 04, 2011
The Sinaloa Story tells of DelRay Mudo and Ava Varazo, two down-and-outs looking for a reasonable life and maybe even a little redemption in a corrupt and violent world. Ava is a Mexican prostitute, beautiful and no victim of circumstance. When DelRay falls in love with her at the drive-in whorehouse where she is the prize, she seizes the chance to break free. They take off for Sinaloa ,Texas, the lone-dog state where "nothin' good ever happens." The far-out border flunkies they meet — Thankful Priest, the one-eyed former football player; Indio Desacato, Ava's pimp and a small-town racketeer; Arkadelphia Quantrill Smith, an octogenarian whose father marched with Shelby in the Iron Brigade; and many others — fill out the sinister and electrifying ride.
The author of more than forty works of fiction, nonfiction, and poetry, which have been translated into over twenty-five languages, BARRY GIFFORD writes distinctly American stories for readers around the globe. From screenplays and librettos to his acclaimed Sailor and… More about Barry Gifford
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Gnomes sit on a stand at the Chelsea Flower Show. The Royal Horticultural Society (RHS) has lifted a ban on gnomes for this year only. The gnomes will be auctioned off as part of the 'Chelsea Centenary Appeal' and to raise funds for the RHS Campaign of School Gardening.
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Genetic Testing for Familial Alzheimer Disease
Effective Date November 20, 2014
Revision Date(s) 11/10/14; 11/11/13; 08/09/11; 02/09/10; 02/10/09; 01/08/08; 05/09/06; 05/10/05; 08/12/03; 12/21/00; 09/07/99
Genetic testing for the diagnosis or risk assessment of Alzheimer disease is considered investigational. Genetic testing includes, but is not limited to, testing for the apolipoprotein E epsilon 4 allele, presenilin genes, amyloid precursor gene, or TREM2.
Genetic testing for Alzheimer disease may be offered along with cerebral spinal fluid (CSF) levels of the Tau protein and AB-42 peptide (see Related Policies). This group of tests may be collectively referred to as the ADMark™ Profile, offered by Athena Diagnostics (Worcester, Mass.).
Alzheimer disease (AD) is the most common cause of dementia in elderly patients. Early-onset AD is much less common but can occur in nonelderly individuals. For late-onset AD, there is a component of risk that runs in families, suggesting the contribution of genetic factors. Early -onset AD has a stronger component of family risk, with clustering in families, thus suggesting an inherited genetic mutation.
AD is commonly associated with a family history; 40% of patients with AD have a least one other afflicted first-degree relative. Numerous genes have been associated with late-onset AD, while mutations in chromosomes 1, 14, and 21 have been associated with early onset familial AD.1
Susceptibility Polymorphism at the Apolipoprotein E Gene
The apolipoprotein E (APOE) lipoprotein is a carrier of cholesterol produced in the liver and brain glial cells. The APOE gene has 3 alleles—epsilon 2, 3, and 4— with the epsilon 3 allele being the most common. Individuals carry 2 APOE alleles. The presence of at least 1 epsilon 4 allele is associated with a 1.2- to 3-fold increased risk of AD, depending on the ethnic group. Among those homozygous for epsilon 4 (about 2% of the population), the risk of AD is higher than for those heterozygous for epsilon 4. The mean age of onset of AD is at about age 68 years for epsilon 4 homozygotes, about 77 years for heterozygotes, and about 85 years for those with no epsilon 4 alleles. About half of patients with sporadic AD carry an epsilon 4 allele. However, not all patients with the allele develop AD. The epsilon 4 allele represents a risk factor for AD rather than a disease-causing mutation. In the absence of APOE testing, first-degree relatives of an individual with sporadic or familial AD are estimated to have a 2- to 4-fold greater risk of developing AD than the general population.2 There is evidence of possible interactions between epsilon 4 alleles, other risk factors for AD [e.g., risk factors for cerebrovascular disease such as smoking, hypertension, hypercholesterolemia,diabetes (3)], and a higher risk of developing AD. However, it is not clear that all risk factors have been taken into account in such studies, including the presence of polymorphisms in other genes that may increase the risk of AD.
Genetic Mutations
Individuals with early -onset familial AD (i.e., before age 65 years but as early as 30 years) form a small subset of AD patients. AD within families of these patients may show an autosomal dominant pattern of inheritance. Pathogenic mutations in three genes have been identified in affected families: amyloid -beta precursor protein gene (APP), presenilin 1 (PSEN1) gene, and presenilin 2 (PSEN2) gene. APP and PSEN1 mutations have 100% penetrance absent death from other causes, while PSEN2 has 95% penetrance. A variety of mutations within these genes has been associated with AD; mutations in PSEN1 appear to be the most common. While only 3% to 5% of all patients with AD have early -onset disease, pathogenic mutations have been identified in up to 70% or more of these patients. Identifiable genetic mutations are, therefore, rare causes of AD.
Testing for the APOE 4 allele among patients with late -onset AD and for APP, PSEN1, or PSEN2 mutations in the rare patient with early-onset AD have been investigated as an aid in diagnosis of patients presenting with symptoms suggestive of AD, or as a technique for risk assessment in asymptomatic patients with a family history of AD. Mutations in PSEN1 and PSEN2 are specific for AD; APP mutations are also found in cerebral hemorrhagic amyloidosis of the Dutch type, a disease in which dementia and brain amyloid plaques are uncommon.
Susceptibility Testing at the Triggering Receptor Expressed on Myeloid Cells 2 Gene
Recent studies identified rs75932628-T, a rare functional substitution for R47H of triggering receptor expressed on myeloid cells 2 (TREM2), as a heterozygous risk variant for late-onset AD. (4, 5) On chromosome 6p21.1, at position 47 (R47H), the T allele of rs75932628, encodes a histidine substitute for arginine in the gene that encodes TREM2.
TREM2 is highly expressed in the brain and is known to have a role in regulating inflammation and phagocytosis. TREM2 may serve a protective role in the brain by suppressing inflammation and clearing it of cell debris, amyloids, and toxic products. A decrease in the function of TREM2 would allow inflammation in the brain to increase and may be a factor in the development of AD. The effect size of the TREM2 variant confers a risk of AD that is similar to the APOE epsilon 4 allele, although it occurs less frequently.
Diagnosis of AD
The diagnosis of AD is divided into three categories: possible, probable, and definite AD. (6) A diagnosis of definite AD requires postmortem confirmation of AD pathology, documenting the presence of extracellular beta amyloid plaques and intraneuronal neurofibrillary tangles in the cerebral cortex. As a result, a diagnosis of definite AD cannot be made during life, and the diagnosis of probable or possible AD is made on clinical grounds. (7) Probable AD dementia is diagnosed clinically when the patient meets core clinical criteria for dementia and has a typical clinical course for AD. Criteria for diagnosis of probable AD have been developed by the National Institute on Aging and the Alzheimer's Association. (6) These criteria require evidence of a specific pattern of cognitive impairment, a typical clinical course, and exclusion of other potential etiologies, as follows:
A diagnosis of possible AD dementia is made when the patient meets most of the AD criteria, but has an atypical course or an etiologically mixed presentation. (6) This may consist of an atypical onset (e.g., sudden onset) or atypical progression. A diagnosis of possible AD is also made when there is another potentially causative systemic or neurologic disorder that is not thought to be the primary etiology of dementia.
Mild cognitive impairment (MCI) is a precursor of AD in many instances. MCI may be diagnosed when there is a change in cognition, but not sufficient impairment for the diagnosis of dementia. (8) Features of MCI are evidence of impairment in one or more cognitive domains and preservation of independence in functional abilities. In some patients, MCI may be a predementia phase of AD. Patients with MCI may undergo ancillary testing (e.g., neuroimaging, laboratory studies, neuropsychological assessment) to rule out vascular, traumatic, and medical causes of cognitive decline and to evaluate genetic factors.
Biomarker evidence has been integrated into the diagnostic criteria for probable and possible AD for use in research settings.6 Other diagnostic tests for AD include CSF levels of Tau protein or betaamyloid precursor protein, as well as PET amyloid imaging. The CSF tests are considered separately in policy No. 2.04.14. PET amyloid imaging is considered in policy No. 6.01.55 on Beta Amyloid Imaging with Positron Emission Tomography for Alzheimer Disease.
Regulatory Status
No U.S. Food and Drug Administration (FDA)‒cleared genotyping tests were found. FDA has not regulated these tests to date. Thus, genotyping is offered as a laboratory-developed test. Clinical laboratories may develop and validate tests in-house ("home-brew") and market them as a laboratory service; such tests must meet the general regulatory standards of the Clinical Laboratory Improvement Act.
Medical policies are systematically developed guidelines that serve as a resource for Company staff when determining coverage for specific medical procedures, drugs or devices. Coverage for medical services is subject to the limits and conditions of the member benefit plan. Members and their providers should consult the member benefit booklet or contact a customer service representative to determine whether there are any benefit limitations applicable to this service or supply. This medical policy does not apply to Medicare Advantage.
Susceptibility Testing at the Apolipoprotein E Gene
The policy regarding apolipoprotein epsilon (APOE) genotyping derives from a 1999 TEC Assessment (9) that offered the following conclusions and observations:
Subsequent to the TEC Assessment, advances in genetic understanding of AD have been considerable, (10) with associations between late -onset AD and more than 20 non-APOE genes suggested. However, relevant literature does not provide evidence supporting clinical utility or benefit from genetic testing for AD.
Tsuang et al. (11) prospectively evaluated APOE testing for AD diagnosis in a community-based case series of older patients presenting with memory complaints but no previous diagnosis of dementia. Of 1,028 potential cases, 970 were evaluated; of these, 425 died and 132 were autopsied; of the 132, 71% were confirmed to have AD. The sensitivity and specificity of APOE epsilon 4 alone were poor, yielding positive (PPV) and negative predictive values (NPV) of 83% and 41% compared with 81% and 56%, all respectively, for clinical diagnosis alone. Using a criterion of positive clinical diagnosis OR APOE epsilon 4 resulted in PPVs and NPVs of 79% and 70%, respectively. A criterion of positive clinical diagnosis and APOE epsilon 4 improved PPV to 88% but at the expense of NPV (40%). Eleven individuals had an epsilon 4 allele without neuropathologically confirmed AD. While APOE epsilon 4 increases disease susceptibility, it is associated with only approximately 50% of AD cases.
The effect of APOE genotype on response to AD therapy has also been examined. The USA-1 Study group found APOE genotype did not predict therapeutic response. (12) Rigaud et al. followed 117 individuals with AD over 36 weeks in an open-label trial of donepezil; 80 (68%) completed the trial. (13) They found no statistically significant effect of APOE genotype on change in cognition (assessed by ADAS-Cog). However, the study was not designed to examine predictive therapeutic response, and there were baseline cognitive differences according to APOE genotype. There is currently insufficient information to make treatment decisions based on APOE subtype.
The REVEAL Study was designed to examine consequences of AD risk assessment by APOE genotyping. (14) Of 289 eligible participants 162 were randomized (mean age, 52.8 years; 73% female; average education, 16.7 years) to either risk assessment based on APOE testing and family history (n=111) or family history alone (n=51). During a one-year follow-up, those undergoing APOE testing with a high-risk genotype were more likely than low-risk or untested individuals to take more vitamins (40% vs. 24% and 30%, respectively), change diet (20% vs. 11% and 7%, respectively), or change exercise behaviors (8% vs. 4% and 5%, respectively). While in this well-educated sample of women there were some behavior changes, none can be considered a meaningful surrogate endpoint.
Genetic Testing for Early -Onset Familial AD
Genetic testing for presenilin 1 (PSEN1) detects 30% to 60% of familial early -onset AD. A number of mutations have been reported scattered throughout the PSEN1 gene, requiring sequencing of the entire gene when the first affected member of a family with an autosomal dominant pattern of AD inheritance is tested. Mutations in amyloid-beta precursor protein (APP) and presenilin 2 (PSEN2) genes account for only a small fraction of cases; it is likely that other causative genes will be discovered.
In 1998, The Alzheimer Disease Working Group of the Stanford Program in Genomics, Ethics, and Society (15) suggested that "predictive or diagnostic genetic testing for highly penetrant mutations (e.g., APP, PSEN1, PSEN2) may be appropriate for individuals from families with a clear autosomal dominant pattern of inheritance, particularly those with a family history of early onset of symptoms." Such families generally have 3 affected members in 2 generations. In the case of diagnostic testing of clearly symptomatic individuals, testing would do little to change diagnostic confidence; however, it might assist excluding other causes of early-onset dementia, as potentially treatable contributory causes would still require exploring. In cases of early detection of questionably symptomatic individuals (i.e., those with mild cognitive impairment, MCI) mutation identification might secure a diagnosis and lead to early treatment. The possibility that earlier diagnosis might lead to improved outcomes, while plausible, is not based on current evidence. Pharmacologic interventions for MCI have not demonstrated benefit in reducing progression to AD. (16)
The nearly complete penetrance of a PSEN1 disease-associated mutation would change the probability of developing AD in an unaffected family member from 50% to either 0% or 100%. Testing for PSEN1 mutations is not useful in predicting age of onset (although it is usually similar to age of onset in affected family members), severity, type of symptoms, or rate of progression in asymptomatic individuals. However, identification of asymptomatic, young adult carriers could allow for reproductive planning. Identification of both symptomatic and asymptomatic carriers could also allow for other types of life planning in advance of incapacitating disease.
It is not uncommon to discover previously unreported PSEN1 mutations in an individual, and without additional family information, these may reflect mutations not associated with disease, or new causative mutations restricted to a single family (private mutation). Thus, interpretation of test results of asymptomatic individuals without identification of a mutation in affected family members may be inconclusive in a significant proportion of patients. Should testing be undertaken, affected family members should be tested first or in conjunction with unaffected family members. When no mutation can be identified in affected family members with a clear autosomal dominant pattern of disease inheritance, the family can be referred to a research program for additional study. Any testing should be performed only in the context of adequate pre- and post-test genetic counseling. Finally, it should be noted that pharmacologic therapy for AD should be based on the patient's symptomatology rather than testing results.
GeneTests.org (available online at: www.genetests.org) notes availability of testing for PSEN1, PSEN2, and APP through a number of laboratories.
A systematic review on the psychological and behavioral impact of genetic testing for AD found few studies on the impact of testing for early onset familial AD. The existing studies generally have small sample sizes and retrospective designs, and the research was conducted in different countries, which may limit the generalizability of the findings. (17)
Mihaescu et al. (18) cite a proposed framework by Khoury et al. (19) for the continuum of translational research that is required to move genomics research findings in AD to clinical and public health applications that benefit population health. The 4 phases of translation research include: (1) Translation of basic genomics research into a potential health care application; (2) Evaluation of the application for the development of evidence-based guidelines; (3) Evaluation of the implementation and use of the application in health care practice; and (4) Evaluation of the achieved population health impact.
Mihaescu et al. conclude that genetic testing for AD is still in the first phase. At this point, the sensitivity and specificity of APOE for detecting individuals at risk of developing AD is too low. For those from families with early -onset, familial AD, there are currently no known preventive measures or treatments that can mitigate the effect of the disease.
Susceptibility Testing at the Triggering Receptor Expressed on Myeloid Cells 2 Gene
Jonsson et al. evaluated 3,550 subjects with AD and found a genome-wide association with only one marker, the T allele of rs75932628 (excluding the ApoE locus and the A673T variant in APP11). (4) The frequency of rs75932628 (triggering receptor expressed on myeloid cells 2 [TREM2]) was then tested in a general population of 110,050 Icelanders of all ages and found to confer a risk of AD of 0.63% (odds ratio [OR], 2.26; 95% confidence interval [CI], 1.71 to 2.98; p=1.13×10(−8)). In the control population of 8,888 patients 85 years of age or older without a diagnosis of AD, TREM2 frequency was 0.46% (OR=2.92; 95% CI: 2.09 to 4.09; p=3.42×10(−10)). In 1,236 cognitively intact controls age 85 or older, the frequency of TREM2 decreased even further to 0.31% (OR=4.66; 95% CI: 2.38 to 9.14; p=7.39×10(−6)). The decrease in TREM2 frequency in elderly patients who are cognitively intact supports the findings associating TREM2 with increasing risk of AD.
Guerriero et al. also found a strong association of the R47H TREM2 variant with AD (p=0.001). (5) Using 3 imputed data sets of genome-wide association AD studies, a meta-analysis found a significant association with the variant and disease (p=0.002). The authors further reported direct genotyping of R47H in 1,994 AD patients, and 4,062 controls found a highly significant association with AD (OR=5.05; 95% CI: 2.77 to 9.16; p=9.0×10(−9)).
No studies were identified that address how the use of the TREM2 rs75932628-T variant might be incorporated into clinical practice.
Ongoing and Unpublished Clinical Trials
An online search of clinicaltrials.gov on August 20, 2014, identified several clinical trials on APOE, APP, PSEN1, and other gene mutation testing and the clinical manifestations in patients with genetic traits suspected to be associated with AD. No studies on TREM2 were identified.
Summary of Evidence
Many genes, including apolipoprotein E (APOE) and triggering receptor expressed on myeloid cells 2 (TREM2), have been associated with late-onset Alzheimer disease (AD). However, the sensitivity and specificity of these genes is low or unknown for diagnosing AD, and genetic testing has not been shown to add value to the diagnosis of AD made clinically. For individuals with early-onset AD, mutations in the presenilin 1 (PSEN1) and amyloid-beta precursor protein (APP) genes are found in a substantial number of patients. However, there is no direct or indirect evidence to establish that clinical outcomes are improved as a result of genetic testing for these mutations.
Therefore, the current evidence does not support genetic testing for AD. The lack of effective methods to prevent the onset of AD or to target AD treatments based on genetic characteristics limits the clinical benefit for such genetic testing. The low sensitivity and specificity of APOE testing for indicating which individuals will progress to AD or as a diagnostic tool, as well as the high likelihood that other genetic findings may affect progression, lend further support to this conclusion. The association of TREM2 and AD has only recently been identified and its clinical utility is unknown. Therefore, genetic testing for AD is considered investigational.
Practice Guidelines and Position Statements
American Academy of Neurology (20)
European Federation of Neurological Sciences (EFNS) (21)
Recommendations: genetic testing (level of evidence not reported)
Screening for known pathogenic mutations can be undertaken in patients with appropriate phenotype or a family history of an autosomal dominant dementia. Testing of patients with familial dementia and of unaffected at-risk-relatives should be accompanied by neurogenetic counseling and undertaken only after full consent and by specialist centers. Presymptomatic testing may be performed in at-risk members of family-carrying mutation. It is recommended that the Huntington's disease protocol is followed for pre-symptomatic testing.
Routine Apo E genotyping is not recommended.
Fourth Canadian Consensus Conference on Diagnosis and Treatment of Dementia
The 2012 Canadian Consensus Conference on Treatment of Dementia (CCCDTD) was held in May 2012 to update the third consensus guidelines referenced next. Previous recommendations were endorsed if there were no changes in the literature. Full articles written by CCCDTD workgroups providing complete background information for the consensus conference are available online (http://www.healthplexus.net/article/2012-canadian-consensus-conference-dementia).
A summary of consensus recommendations from the CCCDTD4 was published by Gauthier et al. in 2012. (22) It is noted in the summary that: "Despite a large number of important advances, the CCCDTD4 concluded that fundamental changes in dementia diagnosis and management have not yet arrived." The 2012 CCCDTD4 summary recommends:
"Testing and longitudinal follow-up of asymptomatic individuals or patients with subjective cognitive impairments not meeting MCI [mild cognitive impairment] criteria, or at-risk individuals (e.g., gene mutation carriers, family history of AD, ApoE epsilon 4) should be restricted to research."
Third Canadian Consensus Conference on Diagnosis and Treatment of Dementia (23)
The third CCCDTD conference recommended the following: Predictive genetic testing for asymptomatic "at risk" individuals with an apparent autosomal dominant inheritance, and a family-specific mutation has been identified:
Genetic screening with APOE genotype in asymptomatic individuals in the general population is not recommended because of the low specificity and sensitivity. (Grade E, Level 2**)
Genetic testing with APOE genotype is not recommended for the purpose of diagnosing AD because the positive and negative predictive values are low.
(Grade E, Level 2**)
**CCCDTD Evidence Ratings
Grade (B) There is fair evidence to support this maneuver.
Grade (E) There is good evidence to recommend against this procedure.
Level 2: (1) Evidence obtained from well-designed controlled trial without randomization, or (2) Evidence obtained from well-designed cohort or case control analytic studies, preferably from more than one center, or (3) Evidence obtained from comparisons between times or places with or without intervention. Dramatic results in uncontrolled experiments are included in this category.
Joint Practice Guidelines of the American College of Genetics and the National Society of Genetic Counselors (2)
For families in which an autosomal dominant AD gene mutation is a possibility:
U.S. Preventive Services Task Force Recommendations
Genetic testing for AD is not a preventive service.
Medicare National Coverage
There is no national coverage determination (NCD). In the absence of an NCD, coverage decisions are left to the discretion of local Medicare carriers.
Molecular pathology procedure, Level 6 (e.g., analysis of 6-10 exons by DNA sequence analysis, mutation scanning or duplication/deletion variants of 11-25 exons)
Molecular pathology procedure, Level 7 (e.g., analysis of 11-25 exons by DNA sequence analysis, mutation scanning or duplication/deletion variants of 26-50 exons, cytogenomic array analysis for neoplasia)
Unlisted molecular pathology procedure
Noncovered item or service
DNA analysis for APOE epsilon 4 allele for susceptibility to Alzheimer's disease
Genetic testing for detection of mutations in the presenilin-1 gene
Type of Service
Place of Service
Laboratory/Reference Laboratory
Add to Medicine Section - New Policy
Replace policy - Coding information added
Replace policy - Policy update; no change in policy statement; CPT codes and references added.
Replace policy - Policy reviewed with literature search; no change to policy statement.
Codes updated - No other changes
Replace policy - Policy reviewed with literature search; information about the CPT codes added to policy guidelines; reference added; no change to policy statement
Update Scope and Disclaimer - No other changes.
Cross References Updated - No other changes.
Replace policy - Policy updated with literature search; no change in policy statement; reference added.
Replace policy - Policy updated with literature search; no change to policy statement. Rational section extensively revised. Code and references added.
Replace policy - Policy updated with literature search; no change to policy statement.
Cross References Updated - No other changes.
Replace policy – Policy updated with literature search; no change in policy statement; reference added.
Policy renumbered to 12.04.13 (previously 2.04.13) and reassigned to new Genetic Testing category.
Replace policy - Policy updated with literature review. References 2-6, 15, 17, 19 added. No change to policy statement. Add Related Policy 6.01.55. CPT codes 81200 – 81479 added effective 1/1/13; code range 83891 – 83912 deleted effective 12/31/12.
Coding update. CPT code 81599, effective 1/1/13, added to policy.
Update Related Policies. Add 12.04.91.
Replace Policy. Policy updated with literature review through July 2013. References 4-5 and 22 added. TREM2 added to investigational policy statement. CPT codes 81405 and 81406 added; 81599 and83914 removed as they are not specific to this policy; 83891 – 83912 removed, as they are now deleted.
Update Related Policies. Remove 12.04.91.
Annual Review. Policy updated with literature review through August 20, 2014. Policy statement unchanged.
Disclaimer: This medical policy is a guide in evaluating the medical necessity of a particular service or treatment. The Company adopts policies after careful review of published peer-reviewed scientific literature, national guidelines and local standards of practice. Since medical technology is constantly changing, the Company reserves the right to review and update policies as appropriate. Member contracts differ in their benefits. Always consult the member benefit booklet or contact a member service representative to determine coverage for a specific medical service or supply. CPT codes, descriptions and materials are copyrighted by the American Medical Association (AMA).


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Candlewick | Feb 03, 2005
| 32 Pages
| 9-1/8 x 10-1/4
| 5-9 years
| Feb 03, 2005
| 32 Pages
| 9-1/8 x 10-1/4
| 5-9 years
"In this crafty story of a cross-country race, numerical division accounts for the narrowing of the field. . . . All lessons should be this gratifying." —PUBLISHERS WEEKLY (starred review)"Bang!" goes the gun. The race is on.Eighty racers explode from the starting gate, determined to win The Great Divide. They surge ahead, rushing toward—OH NO!—the wide hungry mouth of a grand canyon that claims half the racers. And this is only the beginning. More dangers lie ahead, waiting to divide the group once, twice, three times, and more. Will there be anyone left to cross the finish line?
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2 Parks near Mellen, Wisconsin
Cedar, Wisconsin 14.53 miles NE
Saxon, Wisconsin 14.53 miles NE
Odanah, Wisconsin 16.62 miles N
Ashland, Wisconsin 21.23 miles NW
Mellen, Wisconsin (715) 274-5123
Sites: 52 | Latest Rate: $22.00 | 3 Reviews
|Clean Restrooms:
|Clean Showers:
Aug 2011 - $22.00
We stayed in site 005 which had 30A electric in our 41-foot Class A for a week. We were able to walk down to the Bad River, a shallow, wide stream, from the back of site 005. But it was a good 1/2-mile through the woods. Nevertheless, on one walk to the river, I saw a doe and her fawn wading in the river. Though the shower building was about a 1/2-mile from our site, there were several showers and stalls and was kept very clean. However, the high point of this park are the falls along the Bad River. One word: spectacular! - zulu
Jun 2011 - $17.00
This was our fist visit to Copper Falls. It is a very relaxing and quiet place to camp. The sound of the falls and the stream gives you a great night's sleep! - Stefanie
Aug 2009 - $36.00
Expensive for out-of-state (site + permit) but lovely and great hiking! Absolutely make time to hike past the Copper Falls, Cascades, Brownstone Falls, and Devil's Gate. Yummy ice cream at the concession stand. We camped in the North Camp Area - serviced only by vault toilets and no showers. The South Camp Area is too small for a motorhome (according to the ranger - we did not go down there) but they have showers there. Sites 29 through 16 are especially nice for larger rigs. Most sites are electric. - AndersonFamily
Mellen, Wisconsin (map) | (715) 274-6136
Sites: 16 | Latest Rate: $23.00 | 4 Reviews
|Clean Restrooms:
|Clean Showers:
Jun 2011 - $23.00
Not only has our family camped in Wildwood Haven's campground many times, but we have stayed in their cabins as well. The cabins are clean, comfortable, with fully stocked kitchens (you will need to bring your own towels). The owners are wonderful people with a lovely family. We can't say enough about this wonderful "jewel in the woods." The sound of the loons will be your alarm clock in the morning, and send you off to sleep at night. We have never seen sunsets so beautiful as we have sitting on the lake in the evening. Bring your camera! We will be back again next year. Counting the days until we can enjoy this place again. Thanks Wildwood Haven for another great vacation. - Chip Messiner
Jun 2011 - $100.00
My husband and I had a great time at this resort! I have, off and on been visiting this resort for more than 10 years. This is my husband's first visit here and not 24 hours into our 7 night stay he wanted to book again next year! Great owners who are willing to bend over backwards for you to make sure your stay is 100% relaxing! The negative comment left is no were near the truth of this little piece of heaven! - Stefanie
Oct 2010 - $23.00
This campground is so GREAT! I saw 1 bad review but decided to take a chance. We are sooo glad we did. Yes, the sites are small but we had no problem at all with our 26' fifth wheel. The price is great at $23.00. They charge $1.00 to shower and $3.00 to use the dump station which as a "fee for use" we found refreshing. The BAD review was based on the previous owners. New couple just took ownership of this sweet little resort in February 2010. They are working so hard to Fix up, Freshen up and Update as their budget allows. They were painting, sanding and staining every day possible while we were here. Everything is looking so nice, so inviting. They were also very respectful of our privacy and so helpful with information. We were here on an Anniversary trip to see waterfalls (saw 25!!!) So had no time to fish the lake. We hope to get another chance to visit this amazing Resort to do that in the future. Our 8 day stay included 1 weekend with 4 additional sites being filled around us. All sites were quiet and respectful of each other. There is hope to possibly expand to more sites in the future. That could mean the possibility of larger sites, maybe w/ some drive through sites and full hook ups. To do that requires these wonderful people to have a lot of people stay here in campers, tents or their nice cabins. So give them a try, we are so glad we did. - Delores M.


text: Two identical spaceships are under construction. The constructed length of each spaceship is 1.3 km. After being launched, spaceship A moves away from earth at a constant velocity (speed is 0.850c) with respect to the earth. Spaceship B follows in the same direction at a different constant velocity (speed is 0.4c) with respect to the earth. Determine the length that a passenger on one spaceship measures for the other spaceship.


text:
Assistant Art Directors in the United States take home approximately $43K annually on average. There are more female Assistant Art Directors who answered the questionnaire than male, making up 68 percent. Not all workers are lucky enough to have benefits; in fact, slightly less than a fourth are without coverage. Medical insurance is claimed by a strong majority and dental insurance is reported by the larger part. The majority of Assistant Art Directors claim high levels of job satisfaction. The data for this snapshot was collected from individuals who took PayScale's salary survey.
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Assistant art directors have a wide variety of duties and responsibilities and generally work within the art department of a larger organization. Generally, they are lower-level members of the creative department who play the role of a coordinator for projects assigned to the art department and report directly to the art director.Read More...
Those in this position generally act as an intermediary between management and the artists and designers employed by the company. Assistant art directors have daily interactions with the creative team while performing mid-level managerial duties. He/she often responds to requests for projects made by the art director, and helps the director determine what is required and how individual projects should be handled. Offering suggestions and helping to fine-tune ideas is a critical part of the position.
Assistant art directors often act in a clerical capacity, as well, by keeping track of all of submitted work, filling out forms, filing reports, and generating reports. They often interact with clients directly to determine their needs, and also create mock-ups and other samples specifically for those clients. They will often compile and present completed design presentations for clients and/or management, as well.
Another major part of the job involves providing quality control for projects to ensure that the company and/or clients receive the designs/products which best suit the needs of their organization. A bachelor's degree in fine arts or a related field, as well as several years of experience, are generally required for this position.
Job skills reported by Assistant Art Directors are limited. Most notably, skills in Adobe Illustrator, Adobe InDesign, Adobe Photoshop, and Graphic Design are correlated to pay that is above average. For most people, competency in Adobe Photoshop indicates knowledge of Adobe InDesign.
|Highly satisfied
Rated 4 out of 5
based on 25 votes.
68 %
32 %
|Medical: 75%
|Dental: 62%
|Vision: 39%
|None: 23%


text:
"Good, heavy quality cardstock. I chose the teal option and find it to be both professional and eye-catching - I wanted a card that would be easy to find if flipping through a rolodex, since I don't have a logo, and this is exactly what I was looking for."
"I love these business cards! They have the perfect touch of simplicity yet are also unique at the same time. I will be proud to give these cards out to friends, relatives, and business professionals. Overall, I'm very pleased with my order! Thank you."
"The design was super easy to edit to reflect my contact information, and leave off what didn't apply (no job title, no fax, no headings on the back) They come in a nice sturdy little box to keep the cards neat & clean!"
"I love this company. They always have fantastic designs and when I hand out business cards, people are always impressed. I'm a devoted customer."
"Card compliments the stickers and address labels I ordered nicely. Wish I could have gotten the same design for the card as for the stickers and labels, but it was not an option. Print could be a bit more crisp."


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Dark Heresy: Inquisitor's Handbook
Sean M.
Verified Purchaser
Date Added: 04/25/2014 23:18:22
An excellent and well scanned piece. Will be VERY useful for the game I am running, and at an affordable price! Highly recommend!
[5 of 5 Stars!]
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Deathwatch: Ark of Lost Souls
Gary I.
Verified Purchaser
Date Added: 01/28/2014 07:32:51
I purcahsed Ark of Lost Souls for use in a Black Crusade campaign, rather than Deathwatch, and expect to have to adapt heavily when it comes to the detail of stats etc, but then I tend to run combats and campaigns in quite a narrative style so this isn't much of an issue.
As a stimulating environment for adventure the content hits home quite well, with opportunities presented for much diplomacy and influencing as well as for ass-kicking. The content straddles both a single adventure-like exploration and the much wider material for generating 'random' future escapades aboard this (or with adaptation, any) space hulk.
There are some nice options, with a new and terrifying alien race (well, new to me at least...) and some familiar but no less scary opponents. I particularly liked the way that the text makes the Tyrannid threat sound really frightening.
The main adventure encourages you to make a selection between exploring different major factions / enemies on board, and these are all suitable for adaptation to any party. Instead of trying to stop an Orc Waaagh! I can see my Black Crusade chaos marines trying hard to ally with or control it. Similarly, major alien threats can be a source of new tek, evil alliances or simply outright destruction. In Black Crusade, at least, it doesn't take long for characters to rise to the heights of world- or sector-altering actions, and there is plenty in the Ark of Lost Souls to provide that sort of 'grand' opportunity.
I really liked it and the flexibility it gives. The layout is sensible and accessible for me, and the random generation system is actually quite fleshed-out, generating ideas that have depth and subtlety. As has been said, the whole thing is very much amenable to a complete campaign setting, offering challenges on all scales and for all parties. I am seriously thinking of having my players spend quite some time here, with the aim of somehow turning the resources and factions aboard toward their dark ends.
One particularly good feature of a space hulk is the opportunity to expose your party to xenos they might rarely meeet elsewhere, and this is well exploited by the material with plausible backgrounds. Finally, the chance to justify a Harlequin combat !
Good value, with loads of material and lots to stimulate your thinking. Even if you never plan to spend any time on a space hulk, there is so much here to give them more depth and flavour in your games.
Pleased I bought it, and am going back to read it again now !
5 stars would've been for slightly more surprises or twists, or moments of revelation, as my players like those a lot. Shouldn't stop you buying it though - a great resource, especially for anyone that loves the 40k setting.
[4 of 5 Stars!]
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Fireborn: The Fire Within
Geert-Jan W.
Verified Purchaser
Date Added: 01/03/2014 07:48:41
This is like a great mini-campaign to introduce the characters into Fireborn.
Though it is all BUT subtle, letting the player's really dive in directly into the setting.
For player's this might be a good introduction, but for the GM it isn't...
This requires quite a bit of preperation before hand, and a good read through of the adventure before you start.
Make sure you know the rules, and your player's ready to literally jump right into the action.
The adventure starts with peace negotiations in the mythic age as part of a flashback/dream of the player characters.
This is quite confusing, as they only get little bits of info, and know little other then that it's important to stop the war (but not know why it's so incredibly important).
It's played as a vague dream, and it can be a bit hard to get the player's into it and resolve the negotiations in a fluid and flowing manner.
After the dream however, the rest of the campaign gets a bit mroe interesting.
There is a bit of a lower pace moment where some investigative detective work comes around, but they can be sped up or spiced up if your group doesn't like to get into such situations.
My group actually loved this change of pace in between the action scenes.
I think in general, this adventure tries to show and explore all kinds of different perspectives and styles of what Fireborn can provide in adventures for good or ill.
It is very inspiring, and even though not everything will work for your group, going through it at least once does give you a better idea what Fireborn can be, and gives enough ideas to continue the adventures afterwards.
But again, it's rather ambitious for a "introduction", and requires a lot of carefull reading and preperation to get the msot out of this.
I highly recommend going for an easier and shorter pre-adventure or two to get into the system first, so when it comes to combat not everything has to be explained or covered all over again.
It's how I did it, and it worked out well.
[5 of 5 Stars!]
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Fireborn: Player's Handbook
Geert-Jan W.
Verified Purchaser
Date Added: 01/03/2014 07:34:43
A great game, but not for everyone.
I really enjoyed the rpg, and still do in an active rpg group.
I would highly recommend it, even if the rules may not be for everyone, as the setting in itself is awesome enough to steal from in case you feel other rules systems work better for you.
As the setting should be clear to most (Dragons reincarnating, now coming back in the modern age), the mechanical side is what I'll focus on.
The game uses a system called the "dynamic D6" system.
Generally this means you have 4 seperate dice pools representing 1 for active physical actions (attacking, climbing, jumping etc), 1 pool for active mental actions (looking for something, casting magic, trying to focus your mind, use a mental skill etc), and then 2 more defensive "reactive" pools; reactive physical (defending, dodging away, etc.) and reactive mental (resisting influences, noticing an ambush etc).
Now the truly interesting part (that makes it dynamic) is that you can shift these dice pools around based on your skill in an action, and the amount of focus you put into it.
In example, when attacking using your fists to punch someone in the face, it is a Fire melee action.
Your skill in melee is 2, and Fire score is 2.
This normally means you roll 2 dice (Fire 2), but using your skill you can fcus more on your action, and gain 2 extra dice, so to roll 4 instead.
However, those dice need to come from somewhere.. so you lower one of the other dicepools by 2 due to you more aggresive stance performing this action. (which may make you vulnerable to defense or other actions).
That is what I think, makes the system pretty awesome, but it gets better.
During combat it makes things look a bit more like a Matrix style action scene every time an attack is performed.
For each point in for example your Fire score, you can build a sequence.
So Fire 4 would be 4 "small" actions in the sequence, which can allow you to jump through a window, shoot both you guns in your hand (dual wielding pistols), and roll to cover.
(Jump - shoot gun left - shoot gun right - roll for cover)
This does however can make things a bit more complicated/hard to understand in how it works with defending etc. This could have benefited greatly from a better and more clear explanation, but it helps when you have someone who understands the rules to learn from.
(You learn best from experience)
What makes the game a bit more metagamey is the Karma bid, which allows your player to push for a success in any action by spending Karma.
Karma can be spend for 1 extra success each after the dice are rolled, and can allow an action to completely succeed if not enough successes are rolled. The defender also gets to use Karma however, so it becomes a bid...whichever one gets the biggest total of successes will be the winner, but it might still come back to a partial success if not enough excess successes are obtained.
(defender successes and attacker's cancel each other out)
It is rather required however, as Karma will be the thing keeping you alive early in game when you do not have access to draconic powers (which also use Karma).
Combat is lethal!
But there are ofcourse downsides to all this;
- Combat is nice and fast when you get into it, but it takes a while tog et your head around it. Making combat and defence sequences can be hard to envision at first. And if poorly understood..makes for a complicated mess at the table with everyone looking confused.
It is advised to really learn the system before seriously going into large scale complicated combat scenes. Take it easy with just 1 or two player's to slowly introduce.
You will also want the Lost Lore booklet/pdf, it is recomended to answer some questions and give better explanations on soem bits of the game. You can find it still on the G+ community page for Fireborn, along with just about everythign else Fireborn that could still be saved.
(why they did not make everythign available here or on the official FFG pages anymore is beyond me)
- Combat styles are nice, and they add specific sequences you can do based on your "martial arts style", in practice however most seem overpowered due to the payoff effects they can give if they succeed the entire chain.
As well as cumbersome at times, so..I generally moved towards making it more freeform with your own designs of action sequences that fit your style and providing cinematic action dice instead. (they also gain less powerful payoffs, based on the actions they take). It can work as written, but sometimes just feels more restrictive then it probably was intended to be.
- Lethal combat v.s. cinematic combat.
Combat feels like an action movie due to the cinematic "effect", but combat nevertheless is highly lethal as written.
Especially the problem of guns being a bit too overpowered, made me down the damage of guns a little to not shoot everyone dead in their tracks every time one uses them.
Still, guns are illegal in the game, and should be VERY hard to get. Even if you own one, the GM should be carefull to limit them, and give some drawbacks on carrying one to prevent abuse.
But even without guns, combat can be over very quickly, as you have a good chance of wound penalties as well.
I decided to remove the dice penalties, and first have the minor wounds completely fill up before wound penalties develop for every minor wound they would otherwise gain in subsequent attacks.
- You have 2 characters to work through..
First a Scion character, and need to make a whole new character for your dragon self in the mythic age.
There is theoption to sort of "mirror" your Scion to the mythic Age dragon version, but it severely limits your dragon in flexibility and is not recomended.
It's not THAT hard to make a character in Fireborn, so it's recomended to first play an adventure or two with just the Scion character without draconic powers.
Let them learn the system, then make their dragon selves and dive in for reall.
There are many adventures out there that work well for this purpose.
My first intro adventure was "three souls and a smoking gun", a Gencon adventure, which is found as pdf online.
This is also a game that benefits greatly from a few "helpful" bits and pieces to help speed things up.
I used poker chips for Karma, using the colours to make them personal to each player, making it easy to refresh whenever after combat etc.
Having character sheets printed double sided and color coded (look for the costum collour sheets of Scion and dragon characters) is a great help. Whenever a flashback comes around, just flip over the character sheet to the other side.
It helps having stones or (even better) colloured dice for the 4 dice pools.
I use stones, so if they get switched around due to stance changes, theya re easily brought back to the original situation at the start of the next round.
Making it easy for your player's (and yourself) makes this game work even faster :)
[5 of 5 Stars!]
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Black Crusade: Hand of Corruption
Christian S.
Verified Purchaser
Date Added: 12/27/2013 07:11:08
it's a great book, with an epic quest for your group of heretics.
The PDF is crap, it takes 2-20 Seconds to turn a page even on a high end System.
Perhaps a Problem with the encoding of the PDF.
[2 of 5 Stars!]
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Dark Heresy 2nd Edition Beta
louis-olivier f.
Verified Purchaser
Date Added: 12/13/2013 13:04:22
Beaucoup plus proche des autre jdr de 40k, très semblable à only war
Les armes semble maintenant plus proche de leur fluff et les point d'action des combat sont parties ce qui rend les combat plus simple.
Dommage d'avoir ramener les Wounds, le système des blessures était intéressant
aussi dommage d'avoir retirer les ultilisation de stat alternative pour les compétences
[5 of 5 Stars!]
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Dark Heresy 2nd Edition Beta
Marius F.
Verified Purchaser
Date Added: 12/02/2013 00:00:00
If you are new to the Warhammer 40K this book in it's current state gives you a limited view of the setting. All the setting stuff is taken out, but there is a lot of fluff text in the system sections that teaches you something about the setting. From this limited view I like the setting.
This book is mostly about the rules. The rules are presented in a dare I say American way, that is it is super verbose. It spends a lot of pages explaining the rules. Having example for a lot of the rules taking up even more lines, some of the examples have flaws in the math making them more confusing then helpful, but I guess that will be fixed in the final version.
The system hold promise, but I'm disappointed with the amount of choices. I made six characters in order to run the scenario in the back of the book, and I really felt that it was difficult to make all six unique. Some of them ended up a bit too similar for my taste. This might be that the character creation process leaves very little room for customization. You get only a small amount of points to spend as you want.
The system really need more equipment options for all categories, en especially for non-weapons. In addition it needs more elite advantages. The three that are in the book is way to few.
One final note I like the system for influence and subtelty, but I'm very sceptical of the economy system. In all my campaigns as player and gm money has been a important factor. Getting enough of them to afford to get or do something. In this system all you need to do is roll the aquisition dice. And I wonder how the players will feel about it. Is it going to be that they all want the best aquisition character to get them stuff, or will all of them try to get some knowledge of it?
[4 of 5 Stars!]
Dark Heresy 2nd Edition Beta
samuel a.
Verified Purchaser
Date Added: 11/15/2013 12:25:33
It was fun and easy to use, though there are still some bugs in this system I look forward to the final version
[4 of 5 Stars!]
Warhammer Fantasy Roleplay: Player's Guide
Curtis N.
Verified Purchaser
Date Added: 10/02/2013 13:14:25
High quality, searchable, informative. This is a great resource for all Warhammer 3e players. For the player, this and some dice are all you need to get started. GM will probably want to add the Game Master Guide which also includes a short adventure.
Optional components, cards, and sheets can be obtained with the different "Vault" boxes.
[5 of 5 Stars!]
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Anima: Prometheum Exxet - The Supernatural Artifacts
Seth M.
Verified Purchaser
Date Added: 09/21/2013 19:53:10
The product is excellent, the artifact system and general rules work and work well. Overall I'd say this is an excellent Anima product and shows just how good the system can be when compared to DnD or pathfinder.
[5 of 5 Stars!]
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Warhammer Fantasy Roleplay 2nd Edition: Terror in Talabheim
antonio s.
Verified Purchaser
Date Added: 09/07/2013 16:43:32
Very fun to GM, but the players are finding it a bit frustrating I think, as their characters get a bit ill. Still, only 4 sessions in and they seem to be getting the upper hand... ish!
It's WFRP, it's grim and perilous and deadly, and it's better than any generic dungeon bash.
[4 of 5 Stars!]
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Warhammer Fantasy Roleplay 2nd Edition: Realms of Sorcery
Brian P.
Verified Purchaser
Date Added: 08/09/2013 18:08:16
One of the biggest changes between the first and second editions of Warhammer Fantasy Roleplay was the magic system. Driven mostly by changes in the background of the miniatures wargame in between the two editions, the second edition ditched first edition's system of leveled spells and magic points for the new system of color magic. Most of the basics are covered in the main rulebook, of course, but Realms of Sorcery fleshes that out in nearly every direction.
I'll come back to that "nearly."
As you might expect, there's a lot of fluff in the first half of the book. There's a history of magic usage in the Empire up to the point of the Great War Against Chaos, which I can easily summarize as "BURN THE WITCH! Priest are okay though." During the war, Emperor Magnus the Pious sent for aid to Ulthuan, and the High Elves sent three archmages, which was all they could spare at the time. Those archmages went on to help win the war by teaching humans how to safely become wizards, but unlike elves, humans can only use one color at a time safely. Hence the eight orders.
There's a bunch of exposition about the orders as well, with some neat tidbits. Members of the Amber Order don't have a college in Altdorf like the others, instead lairing in the hills outside the city walls. Members of the Grey Order take strong vows never to use their magic for venal financial gain, precisely because it would be so easy for them to do so. The colleges themselves are well-described, too, in a way that lessens their impact on the landscape of Altdorf. I've read that a lot of people don't really like the Colleges of Magic, because they feel like their overtly high fantasy feel damages the presentation of the Warhammer world. I can see that, but there are some colleges that I think actually make things even more mysterious. Like the Azure College, which is a huge building with plenty of high towers to see the stars, but which is never actually visible due to the workings of fate--anyone who looks at it will get bumped into, or trip, or laundry will blow in front of it, or the person will think of something else they have to do, and so on. The Bright College is in the middle of a burned-out stretch of ruins that Altdorfers refuse to move back into, and the Amethyst College appears as a building that's been deserted for decades unless you actually have legitimate business there, in which case you'll probably turn a corner and meet a magister. Or the aforementioned Amber College, in a series of caves. I think it gives the proper mysterious touch to magic that first edition didn't really have.
Then there are the mechanics sections, which I think are really valuable. One of the problems with the spell list system for color magic as of the main book is that because a wizard gets all the spells they would ever learn immediately on taking the Arcane Magic Talent, the whole idea of knowledge-seeking wizards pouring through ancient tomes of arcane lore is restricted to rituals, and the example rituals given in the corebook leave basically no reason why anyone would actually want to cast them based on how difficult they are to use. Honestly, it's probably easier for a Bright Wizard to just set a town on fire than to gather all the materials to use The Awakening of the Slumbering Earth Dragon. The addition of ten extra spells, a choice of multiple lists (each of which only has ten spells), and the Extra Spell Talent to learn the other spells provides both an XP sink for wizards and a reason to seek out knowledge.
There's also a section on witches and witch-hunters, which is short but does a good job.
Finally, there are parts about alchemy, wizards' familiars, and magical items. The alchemy chapter has a very Warhammery (if I can use that word) take on alchemy; potions, being made of perishable ingredients, have a shelf life and can go bad in all sorts of hilarious ways. Familiars provide bonuses for the wizards who use them, but there's a great table of personality descriptions of the familiars to provide some character to them, including options like "Passive-Aggressive," "Know-It-All," and "Raving Mad." There's options for constructed familiars as well as natural animals, so creepy wizards can have their homunculi. The magic items is mostly just a list--in keeping with their rarity, there's no standard rules for making them--but it's nice to have options.
Now, the problems. One of the major problems I had with Realms of Sorcery is its breadth. It's pretty much entirely focused on Imperial magic, and not only that, on modern Imperial magic. I find it really bizarre that there were never any successful wizards in the 2300 years prior to Magnus the Pious, and kind of sad that the other traditions from first edition, like druids or elementalists, weren't included. It does make a nod to druids in the backstory of the Jade Order, and I suppose that the various colors of magic replicate the feel of elementalism--Bright is fire, Azure is Air, Jade is Earth--but it does hammer down the type of acceptable characters to a very defined set. Especially since Tilea, Bretonnia, Estalia, and Kislev exist and presumably have their own type of wizards, but they aren't defined. Kislev does get a breakdown of its magic in Realm of the Ice Queen, but none of the others ever did. It's a persistent problem with the WFRP stuff being so Empire-centric.
The other problem is elves. The book implies that elves should have mechanical differences in the way they interact with magic, but there's no hint on how to handle that. Despite elves being able to use multiple colors without the apparent certainty of harm (or at least, of going crazy and turning evil) that humans have, they apparently still only have the same Apprentice Wizard career that humans do. Unlike Tileans and Estalians, elf wizards had a direct and obvious effect on the magical development of the Empire, and the complete lack of mechanical support for that was pretty disappointing to me.
Other than those points, it's a great sourcebook, and I think it'd be highly valuable for background and antagonist info even in a game with no PC wizards.
[4 of 5 Stars!]
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Dark Heresy 2nd Edition Beta
Daniel M.
Verified Purchaser
Date Added: 08/09/2013 12:42:25
Very excited to start playing this soon. Love the changes to character creation, talents, skills, just about everything. And FFG is being very inclusive and thoughtful about the Beta process which gives me high hopes for the finished product. This new edition addresses a lot of issues I had with 1st ed, specifically that the power creep had gotten to a point where 1st rank characters felt too strong. I like Dark Heresy to be about investigation with combat being either a climax or a result of poor planning on the PC's part. 2nd edition looks like it tones back on that power scale while still allowing room to become very powerful in later ranks.
On a quality note: excellent product; high quality, very crisp and readable at any zoom level. Thoroughly bookmarked, searchable, and easy to navigate; loads quickly on my machine.
[5 of 5 Stars!]
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Dark Heresy 2nd Edition Beta
Alexander M.
Verified Purchaser
Date Added: 08/04/2013 16:27:13
+ reorganization of skills, looks streamlined. No stat looks ignorable for any character class. intrigued to see how it plays out.
+ drastic re-org of talents, much easier discovery of short/long term goals, flexible dependencies instead of "you must be a militant 5... or a pilot 1... or a AD INFINITUM"
+ new character creation process. no artificial class boundaries, easier expression of character concept. Like dnd-next, you get a lightweight layering "origin/background/class" and then buy a few tweaks with starting XP.
+ best darn "adventure at the back of the book" I've ever seen -- instead of your usual plot-rails, it's a template where you tune each faction's heresy-quotent, and then let the faction heads persue their goals and react to PCs. And even a "loyal" faction has an interesting effect on the scenario, as disastrous plans can spring from good intentions.
+ combat rounds have replaced "full/half/react/free" with an action point system, akin to XCOM, that might possibly be excellent... I've cautious optimism about how it'll play out.
+ psi is mostly rogue-trader style power rolls, except fettered/push is a continuous gradient now, and powers are organized into trees like the talents chapter.
+ counting degrees of success/fail has had the math streamlined, which looks like it'll help a bit -- but we've been using fading sun's even faster success metric anyway.
+ damage is more gritty: gone are the HP where you only start taking crits when you hit zero; any hit past the TB+armor of a named character is going to roll on the tables'o'pain for some flavor. As a FATE/narrative GM, this is a win at my table.
(righteous fury no longer needs any to-hit or damage rolls, it's just automatically a HOLYCR*squish* roll on the crit tables.)
- vehicle rules are about 8 pages of clumsy looking mechanics; I'll toss half of them to make it an abstract system.
- like rogue trader, finances are abstracted to availability and influence tests, plus a group's subtlety score for how alert the sector is to there actions-- I like thrones for in person shopping, and abstract for campaign altering stuff, but it's the subtlety thing that smells gamey. Instead, I'm following the spirit of the concept by having influence and subtlety be per faction.
- character sheet doesn't take advantage of the concepts introduced, so I'm busy creating a refactor of the characteristic/skills sector over on my ashnazg.com/blag -- and mine won't have an page-wide inkwash! Common publishers, think of the poor printers you're killing for no reason!
[5 of 5 Stars!]
Dark Heresy 2nd Edition Beta
Sean P.
Verified Purchaser
Date Added: 08/02/2013 14:02:53
This is tough to rate because perhaps it deserves to be rated all on it's own - but on the other hand, it's tough to rate it without the context from where it came from. Also tough to rate because I haven't actually played these Beta rules yet. But there doesn't appear to be any reviews here at this point, so I'll put down my thoughts.
Let's start with this, the WarHammer 40k setting is off the hook. It's dark, rich, grim, complicated, gritty & deadly - but that's been true for a long time and has little to do with this 2nd Edition Beta of the Core Rules.
Dark Heresy 2nd Edition Beta is a widely unexpected rewrite of the rules. Unexpected in it being released at all, since FFG had not released a 2nd Edition in the history of its WH40k RPG product line. Even more unexpected in that the changes are radical enough that the numerous Dark Heresy sourcebooks it sold to its customers the last five years are not mechanically backwards-compatible.
In doing so, FFG has taken a huge risk of alienating the significant fanbase. FFG books are beautiful, well done & a bit pricey. How would you like it if a publisher purposefully chose to make the last 8-10 books you bought from them to be mechanically out-of-date? Exactly. So that's the backstory, the context if you will...and you'll see a big flavorful dose of it on the FFG forums.
So...the 2nd Edition Beta in and of itself? IMO, it's got some intriguing ideas and a decent number of question marks. "Action Points" replace the Half/Full Action scheme and immediately stood out to me as probably offering players more control over their PC's actions in a combat round. Action Points committed to an attack are multiplied by the weapon's Rate of Fire to derive a new key metric called "Rate of Attack". The Degrees of Success/DoS (which is calculated differently in 2nd Edition) on the attack roll are the number of hits, up to the Rate of Attack. The target's DoS from its Evade roll ("Dodge" in v1) subtract from those hits. This is v2's combat core mechanic.
2nd Edition eliminates Hit Points and replaces it with a scheme where you track the # of times a character's been successfully hit. The large majority of the time, and significantly more than in v1, successful hits will result in "Wound Effects", that are much like v1's Critical Wound tables. Past successful attacks cumulatively make a new successful attack more dangerous on that Wound Effect table. The pro of this is more realistic effects from being wounded sooner, rather than a PC showing absolutely no effects from his 4 separate previous wounds and then suddenly being dead. The con is a concern, the way the Wound Effect tables work, that it's much (Much much?) harder to kill someone with the first shot.
There's a new vehicle section, that v1 lacked. The psyker section has vast changes from v1: psyker levels are now 1-10, manifestation test is d100 against Willpower now, no more Minor Powers and no more Phenomenon of the Warp table - straight to the customized Perils table for the Discipline of the power being used. Character generation is very different; they've added a tenth characteristic called "Influence" that's much like the section of the same name in the Dark Heresy Sourcebook Ascension. A new Acolyte group metric called "Subtlety" is introduced. Stats are calculated differently. There's changes everywhere, really.
It's a surprising complete rewrite but there is some intriguing stuff in there. Personally, I think it costs at least one star for not being backwards-compatible with previously published material - and I could see some good customers with a shelf full of books dinging it more than that. I haven't played it yet so I can't be sure it all actually works but, IMO, it looks pretty well done - so I don't see giving it 2 Stars. So that leaves 3 or 4 stars - I optimistically gave it 4 stars.
[4 of 5 Stars!]
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text:
Maybelline Super Stay 24 Hour Concealer
300 reviews
57% would repurchase
Package Quality: 3.6
Price: $$
Package Quality: 3.6
Price: $$
INGREDIENTSAqua/Water/Eau, Isododecane, Propylene Glycol, Diisocetyl Dodecanedioate, Polyglyceryl 4 Isostearate, Nylon 12, Disteardimonium Hectorite, Cetyl/PEG/PPG 10/1 Dimethicone, Hexyl Laurate, Talc, Phenoxyethanol, Sodium Chloride, Propylene Carbonate, Isopropyl Titanium Triisostearate, Methylparaben, Polysorbate 20, Disodium EDTA, Butylparaben, May Contain (+/-): (Titanium Dioxide), CI 77492 (Iron Oxide Yellow), CI 77491 (Iron Oxides), CI 77499 (Iron Oxides)
on 7/6/2012 3:43:00 PM
Age: 19-24
Skin: Combination, Medium, Warm
Hair: Blond, Wavy, Fine
Eyes: Brown
hate it!!!! one of the worst concealers i have tried
on 6/28/2012 2:57:00 PM
Age: 18 & Under
Skin: Acne-prone, Tan, Not Sure
Hair: Brown, Straight, Fine
Eyes: Brown
NEVER again will I buy this product. I got it for $10 to hide my acne scars. IT DID cover it up for a few minutes then afterwards, it would just look cakey and the scars become very visible. i have combo skin. and this is just not for me.
It works great as an undereye concealer though
on 6/22/2012 5:29:00 PM
Age: 18 & Under
Skin: Combination, Fair, Not Sure
Hair: Blond, Wavy, Fine
Eyes: Green
This is my favorite concealer at the moment, it does give amazing coverage but it dries way too fast. I really love this concealer, but i'm still on the hunt for a better one. Will be repurchasing till I find.
on 6/20/2012 3:18:00 AM
Age: 18 & Under
Skin: Normal, Fair-Medium, Not Sure
Hair: Brunette, Other, Other
Eyes: Brown
I have been looking for a good concealer to make my everyday go to concealer and I had been wanting to try this concealer for sometime so I finally did. When I first used it I loved it. Than I found that it didn't last very long at all. I would go through a couple hours of my day and I wouldn't see the concealer doing anything for me anymore. When you first apply it, it is great! But through out the day it fades and cracks a bit. I even set it with powder and had a primer under it. This concealer also made me break out when I used it on spots on my face. It is best to use it under eyes only. I liked this product but I wouldn't repurchase because I feel I can find a concealer that is much better.
on 6/18/2012 11:27:00 PM
Age: 18 & Under
Skin: Combination, Fair, Not Sure
Hair: Black, Other, Other
Eyes: Brown
I had really high expectations for this concealer and its reputation for having great coverage. I needed something with good coverage, so I got this.
I applied some on my scars. Barely looked like I applied anything, except for some cheap makeup that caked up. I tried layering it just to see if I got more coverage. Nope.
Others have said the formula is too dry to be an undereye concealer, but I tried it anyway and it was great! I'd repurchase only to use it as an undereye concealer.
As some have said, the applicator IS rough.
on 6/11/2012 7:54:00 PM
Age: 18 & Under
Skin: Combination, Medium, Not Sure
Hair: Black, Other, Other
Eyes: Black
I'm gonna be honest here.
Let's talk about PACKAGING first. Okay, everyones gotta admit that the packaging sucked. It looked cheap. If Maybeline is gonna compete with other companies. They might as well start with their packaging for this one. It looked about...worth $2.
Second, let's talk about HOW LONG IT LASTED. Well, unfortunately, it didn't stay quite long. It lasted about a couple hours.
Third, QUALITY. It wasn't bad, yet it wasn't as good as I expected it to be. It sort of dried up my skin a bit, and I didn't like that. The product itself (Liquid part) was alright, but a bit cakey. The brush that was came and was used for that product wasn't very nice as well. It was a bid hard on the skin and I don't think that's very flattering to soft skin. It felt like rubbing a scrub to my face. Or maybe like as if my face was being scrubbed against the carpet. Compared to Maybeline's other concealer brushes, the other brushes were soft and nice to apply to my skin.
My skin is a bit dry, but has a hint of oiliness as well. Giving it a combination. Though it was sort of cakey, this would alright for those with super light skin. This didn't go well for me since I'm tan. I got the second to the darkest color, since I know that concealers tend to light up a bit, but even almost at the darkest color, it was still too light!
I gave the overall rating a 2 because it wasn't really good. The price was a bit of a rip off, which I think I got for about $7? I have no idea. I don't remember. Maybe $5.
However, the packaging sucked, the product: Cakey, didn't last 24 hours, and brush: sucked.
Sorry to say this, Maybeline.
on 6/11/2012 6:06:00 PM
Age: 44-55
Skin: Other, Medium, Not Sure
Hair: Silver, Other, Other
Eyes: Hazel
I've spoke elsewhere here of transfer resistant products taking on the texture they are applied over. Transfer resistant foundation will make a dry flaky skin look more so. Acne ,marked, pitted skin will look more so. Great, young skin looks beautiful. Older, dry, lined skin, not so much. Non-transfer resistant foundations will refine a larger variety of skin flaws. Bad skin looks good. Descent skin looks great. Beautiful, perfect skin looks astonishingly glorious. Well I guess you get the idea (the point I'm trying to make.) THIS is a transfer resistant concealer , hence the name: Super Stay 24 Hour Concealer, but it does not have the tell tale signs of transfer resistant. This concealer is smooth. If you've dry under eyes I'd recommend using a richer than usual eye cream under it, but that's okay as once it sets it stays put all day. It's good at covering flaws such as redness around nose, pimples, etc. It's at it's best hiding under eye darkness if you've the proper color. This stuff "rocks" and even works well as an eyeshadow base (over the entire eyelid right on up to the brow.) It doesn't crease very easily and shadows/hi-lites/liner looks more true to it's original color. I love it. Sets a new standard in transfer resistant and affordability!
on 6/9/2012 6:08:00 PM
Age: 44-55
Skin: Dry, Fair, Cool
Hair: Brown, Wavy, Coarse
Eyes: Brown
I'd seen a youtube guru who used this concealer almost faithfully and got good results. I'm pretty fair skinned and have always had dark under-eye circles (blame low blood pressure all my life!). So this concealer seemed to fill the bill - "cheap and cheerful", convenient packaging - perfect for tossing into my gym bag to use after working out and showering or at home...
Well, it's not very good, I'm sorry to have to say. I think I have the "medium" of the 3 shades. It looks chalky and pasty, and doesn't do a great job of covering my dark circles. It's difficult to build up coverage - it just gets chalkier and seems to settle into lines under my eyes. Wear isn't very good either - it seems to sort of melt and go a bit "scaly" as the day wears on - almost as if the product was sort of breaking down. It is cheap but it's still not a product I'd recommend to anyone.
on 6/6/2012 2:46:00 PM
Age: 18 & Under
Skin: Combination, Fair-Medium, Neutral
Hair: Blond, Straight, Fine
Eyes: Blue
I have this in 3 Medium Beige which is totally not my color!
I like the packaging it's really handy. I found the color too orange and i think that is a big problem with drugstore foundation/concealers, they are to orange for me.
It's easy to blend but it really dried out my skin! I have slightly oily skin around my nose and my skin there felt so dry after i use it around my nose. It's looks so cakey even though you apply a little.
This is definitely not my fav. concealer!
I will not recommend this for dry skin at all.
on 6/1/2012 8:55:00 AM
Age: 18 & Under
Skin: Combination, Fair, Not Sure
Hair: Brunette, Other, Other
Eyes: Hazel
I brought this in the lightest color from walmart, it's a good prices but the concealer is HORRIBLE. I tried it when I got home later and it's an unnatural color.
Popular Concealers


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Keep track of your pruners with these well-crafted sheaths. Made from heavy-duty quality grain leather, with waxed thread and extra riveting for strength and durability. A good value. Holster threads through your belt or clips onto your pocket and will hold just about any style of hand pruner. For belt or pocket, high tension metal clip on back.
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Julian Rifat, a former trader at Moore Capital Management LLC, faces eight insider-dealing charges over trades in companies including Barclays Plc and Volkswagen AG, making him one of the most-high profile suspects to face prosecution in a U.K. investigation.
Malcolm Calvert , the ex-partner at JPMorgan Chase & Co. 's Cazenove unit who served a third of his 21-month sentence for insider trading, dropped his appeal of the conviction and a 524,000-pound ($827,000) penalty.
Malcolm Calvert, the former partner at JPMorgan Chase & Co.'s Cazenove unit who is serving a 21-month sentence for insider trading, may have to forfeit about 1 million pounds ($1.5 million), a London court heard today.
Malcolm Calvert , the former partner at JPMorgan Chase & Co. 's Cazenove unit who is serving a 21-month sentence for insider trading, must forfeit 524,000 pounds ($770,000) a London judge ruled today.
Countrywide Financial Corp. investors, led by a group of New York retirement funds, agreed to settle a class-action lawsuit for more than $600 million, a person familiar with the case said.
Galleon Group LLC co-founder Raj Rajaratnam, facing insider-trading charges, asked a judge to throw out government wiretaps of 2,400 of his conversations and evidence prosecutors gathered after listening to them.
New York Attorney General Andrew Cuomo asked a judge to rule without trial that Ezra Merkin and his Gabriel Capital Corp. engaged in fraud by secretly placing client funds with swindler Bernard Madoff.


text:
Are you superstitious? If you are, the next Powerball Lottery drawing may be the one to play, because thirteens are running wild.
After there was no Powerball jackpot winner this past Saturday, the prize for the Saturday, February 11 game will reach an estimated $325 million, with a cash option value of $202.9 million.
Lottery Post reports that this marks the 13th time in the history of United States lotteries that the Powerball jackpot has cleared $300 million. And that has happened because no one has won the prize for 13 straight drawings.
According to 6abc.com, five players matched the first five numbers without the Powerball, to earn $1 million. One of them came from New Jersey.
Winning numbers for the Wednesday, Feb. 8, 2012 game were 17, 28, 38, 39, and 51, and the Powerball number was 33.
Philly.com reports that the Powerball jackpot has risen $125 million in one week. The game's highest annuity prize of all time was $365 million, won in February 2006. But Saturday's drawing will set a new Powerball record for a lump sum payout at $202.9 million, eclipsing the old mark of $177 million.
Mega Millions holds the record for an annuity jackpot in the U.S. at $390 million and a couple in Cape May County split half of $233.1 million. Powerball has had 12 of the top 25 jackpots of all time in United States lottery history.
There are no official statistics about the number 13 being lucky or unlucky. But according to Lottery Post, back in 2005, research from the United Kingdom National Lottery found that the No.13 ball has only been chosen 108 times as a main ball, and only 12 times as a bonus ball in 11 years of the game there.


text:
Peterson ready to help Vikings chase playoff berth
"What inspired you to be the best?" he wishes he could ask the Bears great, who died in 1999. "How did he deal with success and fame? If he could do anything different, what would it be? What would he have done?"
Peterson speaks to Vikings coach Leslie Frazier about Payton. Frazier was a teammate of Payton's and has routinely said he sees striking similarities between the two, on and off the field.
His name is up there with Tom Brady and Peyton Manning in the MVP discussion, and an MVP win for Peterson would break a string of five straight given to quarterbacks. He's certainly showing that an offense can be successful while relying heavily on the running game and validating the Vikings' decision to invest heavily in him with a lucrative contract extension before last season.
"I definitely want to keep the running backs highlighted," Peterson said. "It's started to turn into more of a spread, quarterback-friendly NFL. But just keep letting them know that there are going to be running backs that can do this.
"Just give young guys the inspiration to try to be better than me. Just inspire them to get on top of their game to be better so that running backs continue to prosper in this league and have coaches and organizations respect us so we can continue to not only play the game we love, but take care of our family."
LaDainian Tomlinson, another running back with Texas roots, won the MVP award in 2006, the last time a non-quarterback has won the award.
"It would definitely be nice to do that," Peterson said. "And I feel like it will happen. I just have the confidence in myself and the guys that surround me who have played such a big part in this the whole season."
One more game to strengthen his case. One more game to reel in those records and try to extend this magical season for at least another week.
"Coming into the season after going through the rehab process, I just told myself that I wanted to lead my team to a championship and make sure that I contribute and do my part," Peterson said. "I've been doing it. I just ask God to continue to bless me."
AP Sports Writer Teresa M. Walker in Nashville, Tenn., contributed to this story.
Follow Jon Krawczynski on Twitter: http://twitter.com/APKrawczynski
Online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL


text:
Originally written on MyTeamRivals.com | Last updated 4/12/12
Dr. James Andrews and his ground-breaking Tommy John surgical procedure has given many years of service back to Big Leaguers who may have otherwise been forced to retire. It has also provided many extra years of thrills for fans. Without the surgery, we don't have Strasburg. We don't have Adam Wainwright. We don't have A LOT of big time stars. But, not everyone recovers as planned. Enter, Joey Devine. Despite the surname, his career path has been anything but. After a promising 2008 season where he went 6-1 in 42 appearances with a STUNNING .59 ERA, dude got kissed by the angel of shoulder death and was forced to have the highly effective surgery. Unlike most people though, two years later, he still hadn't recovered properly; and now, in 2012, it appears Mr. Devine has to have Tommy John surgery AGAIN. If Devine ever makes it back to the Bigs, you bet I'm gonna stand and applaud his every appearance. For the fortitude it must take to stay focused, to battle back against such adversi...
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America's top hospital gets failing grade in treatment of its workers
Hospital workers were on the march in the pouring rain earlier this month at John Hopkins Hospital saying: "America's Number One Hospital - Keeping Workers in Poverty."
Fast food workers strike in 150 U.S. cities and 36 countries
"It feels good to be a part of history. It's been a year that fast-food workers first went on strike for $15 and a union and now our movement has spread all over the world."
Trumka: Minimum wage opponents 'delusional' if they think they've won
AFL-CIO President Richard Trumka condemned the continued right-wing obstruction preventing millions of working families from getting a much-needed boost in income.
Today in labor history: Nazis destroy unions
On May 2, 1933, Adolf Hitler's storm troopers occupied all trade union headquarters across Germany, and union leaders were arrested and put in prison or concentration camps.
Postal workers march to save the mail in 50 states
Chanting "Whose post office? The people's post office!" Postal Workers and their union allies marched in Washington protesting the USPS scheme to run postal services out of Staples stores.
Thousands turn out for Labor Notes conference
Over 2,000 trade union activists and friends attended the conference, which was geared toward helping unionists find ways to build coalitions and win struggles in today's difficult political climate.
Executive Paywatch highlights gap between rich CEOs and their workers
"Tax day is a day when we all pitch in, right? Yet for a small number of wealthy people, it represents making money from the sacrifice of others - a ridiculous amount of money."
NLRB heads to court to stop Kellogg's lockout of Memphis workers
The decision to head for court "recognizes Kellogg's illegal positions and iron-fisted conduct were so destructive to these workers' rights ."
Hartford fast-food workers protest wage theft
Fast-food workers and community and faith leaders protested systemic wage theft in the industry, just after the first-ever national poll of fast-food workers showed companies lare stealing money from 89 percent of their employees.
Colombian union leaders say killings continue
Three years after it was added as a side pact to the controversial U.S.-Colombia "free trade" pact, the Labor Action Plan designed to improve workers' lot and their rights is a failure.


text:
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Britney Spears Breakdown Blabber Blah Blah Blah
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Your boat is brok-ed !!! My mom and I were just sitting and staring out on the lake when the next door neighbor and his
Amanda Bynes Shares A Path Similar To Britney Spears'
Amanda Bynes is living a public breakdown all too similarly to Britney's infamous 2007, including the latest news Amanda shaved her locks because a
Tonight Alive Release "Breakdown" Video
Tonight Alive's brand new song–"Breakdown"– and video featuring Benji Madden (Good Charlotte) has just been released! Here's the behind-the-scenes: And now, the music video: #MusicRules So, what do
Buzznet Breakdown 2/24
It's time for our Buzznet breakdown! Here are our top 10 posts from the past week. We have some awesome stuff from fashion, music, celebs
Music On, World Off: "Breakdown" by Christian Burns
Music On, World Off is basically me telling you guys about a certain song I'm infatuated with while attempting to attach some moral story behind
Assisti: Amanhecer pt 2.
Depois de 2 semanas assiti Amanhecer pt 2 com meus amigos, e posso dizer que superou minhas expectativas, e me surpreendeu, teve troll, o mais
Sam Lutfi Hid Britney's Dogs
Lawyers representing Britney's family claim Sam Lutfi would hide Britney's dog, watch her cry, and "find" it so he'd appear heroic, reports TMZ.com. They say
2 pics
Lawyers Blame Justin Timberlake For Britney Spears Breakdown
Britney and Lynne's lawyers in the defamation case blame Justin Timberlake for her downward spiral that ultimately got her 5150′d, reports TMZ.com. The lawyers claim the
www.nobodies.tv Facebook- http://www.facebook.com/NobodiesShowTwitter- http://www.twitter.com/WatchNobodiesKinsey deals with a very abrupt, life-changing break-up.Starring (in order of appearance):Kinsey DimentOwen MartinJocelyn Jolley
Demi Lovato: I Can Relate To Britney
Britney and Demi Lovato endured very public breakdowns in the recent years, as well as substantial "comebacks," something Demi relates to Britney about. "Britney is such
Album review: Memphis May Fire-Challenger
Memphis May Fire's new cd "Challenger" is definitly not one to pass by. The tenasious new album picks up right where their previous cd "
The BAD Break-Up Playlist
I've been in this groove lately of just listening to music and making a bunch of playlists for different situations. Here is one for bad


text:
"Every week or so, I take a journey down to the local fish wholesalers, where I purchase assorted feeders, dry goods and the occasional oddball fish—herp people are big on things like lungfish, electric eels, and the like. Before I leave, I always ask the guy who takes care of our amphibians to let me know what we might need. He typically replies, "Oh, the usual Woolworth's assortment." When he and I were kids, before…"
"Pet Business: What are some of the benefits of utilizing LED lighting in a terrarium setup? How has LED technology improved upon previous technology?Rita Zarate: LED lighting has some very unique benefits for terrarium lighting applications. LEDs are very efficient and use very little energy, making them inexpensive to operate.…"
"I was sitting outside my store the other day, eating lunch and watching the turtles lazily paddle around their lagoon. As a family sauntered out of the store, I heard the mother say, "I can't believe they have so many rattlesnakes—and such a variety of colors. Is that even legal?"This…"
"The evolution of legislation governing the sale and ownership of wildlife in San Francisco begins with an urban legend. There is scant documentation of the incident, but knowing the parties concerned, it seems plausible, and the politician at the heart of the story has not confirmed or denied the story…"
"I cannot count the number of times folks have walked up to me in the shop and said, "You have about the scariest job in the world." I don't, of course. Not even close. Although, admittedly, dealing with the general public is terrifying. I do know what they are getting…"