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Winter!: Prepare for holiday gaming!
This was the first red faction game I played and I liked it. Repetitive after a while but the story is decent but the destructive environment is what keeps you playing. Unfortunately the game is too short.
Game Traits applied to Red Faction: Guerrilla (PS3) by wolf503
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I have a domain name which is 100KHomeBaseBusiness.com that I have set up for a sales funnel page from word press using the clone my website newest theme. In that theme one of the features is the fact that we can have regular blog running along with sales page.
For my blog area post and information I had the support at CMW the domain name http://100KHomeBasebusiness.com/home
The issue now is I cannot get the feed for the RSS now on the site. The cbnet pinger is on the site also. Have any ideas what I can to do.


text:
The Reformation
Book by Stephen Nichols
Mention history and some might struggle to stifle a yawn. But when presented as a narrative it can often be compelling reading. Stephen J. Nichols takes a key period in time, the Reformation, and presents its major players in a … Learn More
The Israel of God: Yesterday, Today, and Tomorrow
Book by O. Palmer Robertson
Many Christians today are confused over the meaning and purpose of Israel. The Israel of God, Dr. O. Palmer Robertson explores Israel's importance theologically and practically, allowing the whole Bible to define who Israel was, is, and will be. "Palmer … Learn MorePaperback $13.00 $10.40 Add to Cart
The Shadow of Christ in the Law of Moses
Book by Vern Poythress
The books of the Pentateuch are among the most foundational for understanding the message and significance of the biblical story. They are also among the least understood. A clear, in-depth, and Christ-centered introduction to these books is, therefore, a pressing … Learn MorePaperback $23.00 $18.40 Add to Cart
Trinity Hymnal
For more than 40 years, the Trinity Hymnal has been used in churches around the country. Containing hymns especially for churches in the Protestant Reformed tradition, the Trinity Hymnal has been established as one of the more theologically sound hymnals … Learn MoreHardcover $17.95 Add to Cart
The Westminster Confession Into the 21st Century
Book by Ligon Duncan
This important collection of essays seeks to place the work of the Westminster Assembly in its historical, theological, political and social setting and challenge inaccurate historical assertions that have since become commonplace. It places Westminster in its relation to earlier … Learn MoreHardcover $38.00 $30.40 Add to Cart
Illustrated Dictionary of the Bible
Book by Various Authors
Most one-volume Bible dictionaries are aimed at scholars and specialists - people who already have a thorough understanding of the Bible. But this dictionary was designed, written, and edited with the needs of general readers in mind. People with no … Learn MoreHardcover $30.00 $24.00 Add to Cart
Jonathan Edwards: A Guided Tour of His Life and Thought
Book by Stephen Nichols
Jonathan Edwards, a leader in the Great Awakening during the eighteenth century, still has much to teach the church. Evangelicals are rediscovering him through the efforts of several authors (John Gerstner, Iain Murray, Harry Stout, and others) and publishers (Banner … Learn More
Living for God's Glory: An Introduction to Calvinism
Book by Joel Beeke
The theological system known as Calvinism is often caricatured as harsh, dour, and illogical. But as Dr. Joel R. Beeke argues in this important new book, this image could not be further from the truth. Beeke, a pastor, educator, editor, … Learn MoreHardcover $24.00 $19.20 Add to Cart
Also available in two other formats
The Heidelberg Catechism
The Heidelberg Catechism is a summary of biblical doctrine that can be used as a teaching tool for both adults and children. It is the inspiration for Tabletalk's daily studies in 2012 and an excellent resource for private study, family … Learn MorePaperback $8.00 $5.60 Add to Cart
The Lightlings
Book by R.C. Sproul
In The Lightlings, Dr. R.C. Sproul weaves an allegorical tale that captures the essence of the biblical story of redemption in a manner that will fascinate and delight children. A race of tiny beings known as lightlings are a picture … Learn MoreHardcover $18.00 $14.40 Add to Cart
Also available in three other formats
God's Undertaker: Has Science Buried God?
Book by John Lennox
Some commentators claim that science has finally killed the concept of God by virtue of its own all-encompassing explanations of reality. Atheism, they say, is the only intellectually tenable position, and any attempt to reintroduce God is likely to impede … Learn More
Can I Know God's Will?
Book by R.C. Sproul
As human beings, we long to know that our lives will unfold in ways that we will find pleasant and rewarding. As Christians, we have a different focus—we want our lives to be pleasing to God. Thus, we ponder His … Learn MorePaperback $4.00 $3.20 Add to Cart
Also available in one other format
Reformation Sketches
Book by W. Robert Godfrey
The sketches in this book strive to show that the Reformation remains vitally important for Christians today. Reformers and preachers of the sixteenth century were the best educated, most godly, and most faithful group of leaders the church has ever … Learn MorePaperback $13.00 $10.40 Add to Cart


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Originally written on Helmet2Helmet | Last updated 12/2/12
Ridiculous tattoos have long been a staple of sports fandom, with each new splotch of ink seemingly outdoing the last. This next one is no different. One Twitter user, QuinnNYG, proved he's a "true fan" of Steve Weatherford, getting the signature of the Giants punter tattooed on his leg. Yes, you read that correctly. Here's the proof. https://twitter.com/QuinnNYG/status/272544130708668416 Weatherford, a frequent user of several social media outlets, was impressed by the gesture. He tweeted that it's "committed," and on his Facebook profile -- friend him if you haven't already -- called it "pure craziness." Most of us would agree with the latter. While Weatherford is among the best at his position, it's absurd to get another person's signature permanently pressed into your skin. But, hey, who am I to judge? We all have our trip. Different strokes. Yadda yadda yadda.
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Free Kindergarten Draws a Crowd
emerton Parents and children packed the gym at the Bremerton School District Administration Building on Tuesday evening for cookies, face-painting and the opportunity to register their children for the district's first free full-day kindergarten session.

"The wonderful turnout tonight shows the number of people that need this service," said Linda Sullivan-Dudzic, special programs director for Bremerton schools. "We've already started with more registration than we've ever had. People have shown so much support for our schools and we want to show support for families."

The preschool and kindergarten registration fair featured representatives from child-care services, health services, transportation and the Kitsap Regional Library to show parents the availability of resources. Children enjoyed making balloons, face-painting and jumping in an inflatable moon bounce.

Bremerton will be one of the largest districts in the state to offer free full-day kindergarten starting this fall. The option is available to families who either live in or have child care in the district and to residents of the Jackson Park Naval Housing area. Out of district families will be accepted as space permits.

All districts offer a half-day of kindergarten free and some offer a full-day option. Tuition fees are usually more than $2,000 per year per child.

In Bremerton, parents, administrators and teachers are excited about the chance to double instruction for kindergartners.

"There's so much more that we can get done now that we have the full-day option. In the afternoon extensions, we can include science, music, P.E. and library visits in our curriculum," said Desiree Hall, a kindergarten teacher at Naval Avenue Elementary School.

Many also say that this is an important service for families who might not be able to afford full-day kindergarten or day care.

Adell Taylor recently moved to Bangor submarine base with her husband and four children. If her daughter, Angel, is able to enroll in full-day kindergarten, Taylor will be able to go back to school to become a licensed practical nurse.

"We are a low-income family and my husband is the only one who works and supports our family of six," Taylor said. "It would be such a great help if Angel got into full-day kindergarten and I could go back to school."

While many are excited about the full-day kindergarten option, it did come as a surprise to some families.

Debra Andersen said when she first heard about the change, she was unsure if she should send her daughter, Kathryne, to full-day kindergarten at Naval Avenue Elementary. But after a couple of days she decided it would be worthwhile.

"I'm so excited for the opportunity Kathryne will have since she will be getting a good, solid educational foundation. Tonight has been a phenomenal turnout and when we walked in tonight, her face just lit up."

Krista Carlson, community service coordinator for Bremerton schools, said the district had more than 180 kindergarten registrations at this year's fair compared with 30 last year.

She said "phones have been ringing off the hook" since the all-day kindergarten program was announced.

Parents can still sign up for the program. For information call (360) 478-5137 or visit www.bremertonschools.org.

Kindergarten Availability

South Kitsap: No full-day kindergarten program.

Central Kitsap: Full-day kindergarten offered; tuition — $2,200, $25 deposit required at registration.

Bainbridge Island: Full-day kindergarten tuition offered; tuition — $2,800.

North Kitsap: Full-day kindergarten offered; tuition — $2,925, deposit of $25 required at registration, but will be refunded if there are not enough students to fill a class.

North Mason: No full-day kindergarten program.e<
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text:
Board of Trustees Meeting at Twin Falls Public Library
Event Details
Date(s) & Time(s)::
October 10, 2012 at 4:30 PM until 6:00 PM
Location: Twin Falls Public Library, 201 4th Ave E, Twin Falls, ID 83301
Phone: (208) 733-2964 ext 109
Email: email@example.com
Link: http://www.twinfallspubliclibrary.org
Event Description
The public is welcome to attend the monthly meeting of the TFPL Board of Trustees. The board's role is to establish and review policies and rules of use for the governance of the library.Return to event list.
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Business leader: George Soros is now betting against a rising Dow, and the rush of private equity flotations has an end-of-the-party feel. Is it over?
Peter Preston: Journalists on three titles in northern England owned by Gannett are to strike over plans to move editing work to south Wales. But this is of a piece with the US firm's attitude to print media
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the ultimate standard by which all hardware is judged
"Yes that's cool, but can it play doom?"
автор: Hyperion2010 13 сентября 2007
The mintest game ever!!
Still entertains.
Still entertains.
1: Doom is mint, u think so?
2: Yeah!
2: Yeah!
автор: j 8 декабря 2004
The street name for a synthetic marijuana that gets you higher than you could ever imagine. This synthetic marijuana is legal and sold over the counter as herbal incense. The active ingredient that replicates THC is JWH-18.
"Are you ready for some DOOM?"
"Sit tight, I just packed one full of DOOM!!"
"Sit tight, I just packed one full of DOOM!!"
автор: LakSom 17 марта 2010
a game where you have 2 pwn demonic forces of hell.
me, i just shoot anything that moves
me, i just shoot anything that moves
me: die freaks (boom)
david: that is your men
me: fuck, doom is quality
david: that is your men
me: fuck, doom is quality
автор: mr pwner 14 сентября 2006
I'm going to sing the doom song now
do doom doom dom do de dooooooom dooom do doom deee doooom do dom dooom dieb
автор: Xenon 16 апреля 2005
A dumbass
that girl is such a dooms, she washes her hair in the toilet.
автор: jewlmykkat 6 декабря 2010
A general word, once meaning impending fire and brimstone, that now goes with anything. Most often used by Jhonen Vasquez.
"Would you like some pork? with a little DOOM on it?"
автор: Hanami 13 октября 2003


text:
Reader voices: Veterans get zilch from Romney-Ryan
In Mitt Romney's recent speech to the VFW he assured the audience he believed every veteran "deserves care second to none."
GOP Convention brews lies and hate
I can't recall another Republican Convention more full of lies, demagogy, sexism and racism as the one just concluded in Tampa.
Why we need a massive jobs program
Seven years later, the downtown and North Side sections still had pockets of the upwardly mobile, but the hustle and bustle had definitely diminished.
Romney part of Global Tax Dodging, Inc.
Mitt Romney is a tax dodger. That's according to 950 pages of confidential financial documents about his offshore Cayman Island investments.
Ryan and Akin serve notice of imminent threat to democracy
Every inch of social progress secured in the course of struggle over the past several decades is subject to reversal in the event of a government takeover by the Republican Party.
What does it take to "Rebuild the Dream"?
In September 2009, Van Jones stepped down as Special Advisor under a barrage of right-wing criticism of his youthful flirtation with leftist politics.
Akin, Ryan, rape and Republican hypocrisy
Fierce opposition to women's reproductive rights, including the right to decide whether or not to bear a child, has been the agenda of the Republican Party for quite some time now.
The meaning of Romney's Ryan choice
The strategy and tactics of this time means defeating Romney/Ryan and re-electing Obama/Biden. The alternative is moving further in negative territory.
Being president takes more than a businessman
As we roll, or descend, into another presidential campaign, we have once again an opportunity to think about the qualities that we look for in our leader.
National Lampoon's Romney vacation?
While Romney's camp calls his trip "a great success," it appears to have been anything but successful. In a trip that should have been a breeze, he has succeeded in angering our closest ally, as well as liberals and conservatives alike.


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Are you J J Vanderhaeghen?Claim your profile
Publications (149)709.73 Total impact
- SourceAvailable from: Zaida Díaz-Cabiale
Article: Adenosine A2A agonist CGS 21680 decreases the affinity of dopamine D2 receptors for dopamine in human striatum[Show abstract] [Hide abstract]
ABSTRACT: Adenosine A2A receptors (A2AR) and dopamine D2 receptors (D2R) are highly concentrated in the striatum, where they are co-localized and exert reciprocal antagonistic interactions. It has been suggested that the A2R/D2R interactions might provide a therapeutic approach for basal ganglia disorders, such as Parkinson's disease, and schizophrenia. In the present work evidence is presented for the existence of an A2AR/D2R interaction in human brain by using quantitative autoradi- ography. The areas analyzed were the dorsal caudate nucleus and putamen. Parallel studies were performed in rat striatal sections. The A2AR agonist CGS 21680 was found to significantly increase IC50 values of competitive inhibition curves of the D2R/D3R antagonist [125I]iodosulpiride vs dopamine both in rat striatal and human striatal brain sections.Neuroreport 08/2001; 12(9):1831-4. DOI:10.1097/00001756-200107030-00014 · 1.64 Impact Factor
Article: CD34 immunoreactivity and interstitial cells of Cajal in the human and mouse gastrointestinal tract[Show abstract] [Hide abstract]
ABSTRACT: Immunoreactivity for the tyrosine kinase receptor Kit (Kit-ir) is an established marker for the interstitial cells of Cajal (ICC) of the gut. Recently, the presence of CD34 immunoreactivity (CD34-ir) has been reported in Kit-ir ICC around the myenteric plexus in human small intestine. Conversely, we observed that CD34-ir labeled Kit-negative fibroblast-like cells, closely adjacent to, but distinct from, the Kit-ir ICC. The existence of cells expressing both CD34-ir and Kit-ir remains controversial. CD34-ir and Kit-ir were studied by high-resolution confocal microscopy on cryostat sections of human and murine gut as well as murine whole-mounts, using specific antibodies raised to human and murine CD34, respectively. CD34-ir labeled numerous cells in all parts of the gut, in man and in mouse. CD34-ir was consistently observed in Kit-negative cells, distinct from the closely adjacent Kit-ir ICC. Thin processes of both cell types intermingled extensively, often at the limit of resolution for light microscopy. CD34-ir was also observed in Kit-negative mesenchymal cells in the submucosa, in capillaries and in mesothelial cells. CD34-ir is not a marker for Kit-ir ICC in the human and murine gut. No CD34-ir, Kit-ir-expressing cells were encountered. Conversely, CD34-ir cells, closely adjacent to, but distinct from, Kit-ir ICC were consistently identified. The intimate relationship between these cells may offer an alternative explanation for reports of CD34 and Kit co-localization. The ontogeny and function of CD34-ir cells in the gut, as well as the origin of gastrointestinal stromal tumors, remain unclear.Cell and Tissue Research 12/2000; 302(2):145-53. DOI:10.1007/s004410000264 · 3.33 Impact Factor
Article: Blockade of A1 receptors by caffeine induces c-fos, zif-268 and ARC expression in the striatum through different interactions with the dopamine system.Advances in Experimental Medicine and Biology 02/2000; 486:207-16. · 2.01 Impact Factor
Article: Caffeine-mediated induction of c-fos, zif-268 and arc expression through A1 receptors in the striatum: different interactions with the dopaminergic system.[Show abstract] [Hide abstract]
ABSTRACT: Adenosine and the adenosine receptor antagonist, caffeine, modulate locomotor activity and striatal neuropeptide expression through interactions with the dopaminergic system by mechanisms which remain partially undetermined. We addressed this question by using quantitative immunocytochemistry and in situ hybridization, combined with retrograde tracing of striatal neurons, to characterize the mechanism(s) leading to the striatal increase in the immediate early genes (IEG), c-fos, zif-268 and arc, following a single injection of caffeine or the A1 antagonist, 1,3-dipropyl-8-cyclopentylxanthine (DPCPX). Caffeine and DPCPX induced c-fos, zif-268 and arc expression, both at mRNA and protein levels, in large proportions of striatonigral and striatopallidal neurons. The involvement of dopamine systems was evaluated by manipulations of the dopaminergic transmission. Quinpirole, a D2 agonist, almost completely blocked the caffeine-induced IEG increase in both striatopallidal and striatonigral neurons. Conversely, the lesion of the nigrostriatal pathway and the D1 antagonist SCH23390 abolished the caffeine effects in striatonigral neurons but had no or slight effect, respectively, on its action in striatopallidal neurons. These observations demonstrate that caffeine- and DPCPX-mediated IEG inductions involved different mechanisms in striatonigral and striatopallidal neurons through blockade of A1 receptors. Immediate early gene inductions result from a stimulation of dopamine release in striatonigral neurons and from activation of glutamate release and probably also acetylcholine release in striatopallidal neurons. These results also support the idea that, besides A2A receptors, adenosine acting at the A1 receptor plays pivotal functions in the basal ganglia physiology and that blockade of these receptors by specific or nonspecific antagonists, DPCPX and caffeine, may influence a broad range of neuronal functions in the striatum.European Journal of Neuroscience 10/1999; 11(9):3101-14. · 3.67 Impact Factor
Article: Distribution of the nociceptin and nocistatin precursor transcript in the mouse central nervous system.[Show abstract] [Hide abstract]
ABSTRACT: The distribution of prepronociceptin messenger RNA, the recently identified endogenous ligand of the ORL1 receptor (opioid receptor-like-1), has been studied in the adult mouse central nervous system using in situ hybridization. Prepronociceptin is a new peptide precursor that generates, upon maturation, at least three bioactive peptides: nociceptin, noc2 and the recently described nocistatin. Considering both the density of labeled neurons per region and their intensity of labeling, the distribution of prepronociceptin messenger RNA-containing neurons can be summarized as follows: the highest level of prepronociceptin messenger RNA expression was detected in the septohippocampal nucleus, bed nucleus of the stria terminalis, central amygdaloid nucleus, and in selective thalamic nuclei such as the parafascicular, reticular, ventral lateral geniculate and zona incerta. High to moderate levels of prepronociceptin messenger RNA expression were detected in the lateral, ventral and medial septum, and were evident in brainstem structures implicated in descending antinociceptive pathways (e.g., the gigantocellular nucleus, raphe magnus nucleus, periaqueductal gray matter), and also observed in association with auditory relay nuclei such as the inferior colliculi, lateral lemniscus nucleus, medioventral preolivary nucleus and lateral superior nucleus. A moderate level of prepronociceptin messenger RNA expression was observed in the medial preoptic nucleus, ventromedial preoptic nucleus, periventricular nucleus, pedonculopontine tegmental nucleus, solitary tract nucleus and spinal trigeminal nucleus. A weak level of prepronociceptin messenger RNA expression was present in some areas, such as the cerebral cortex, endopiriform cortex, hippocampal formation, medial amygdaloid nucleus, anterior hypothalamic area, medial mammillary hypothalamic nuclei, retrorubral field and substantia nigra pars compacta. No labeled cells could be found in the caudate-putamen, nucleus accumbens and ventral tegmental area. The present data confirm that nociceptin is expressed in a broad array of regions of the central nervous system. In good correlation with the presently known physiological actions of nociceptin, they include, amongst others, brain areas conveying/integrating pain and auditory sensory afferences.Neuroscience 02/1999; 91(3):991-1007. DOI:10.1016/S0306-4522(98)00683-6 · 3.33 Impact Factor
Article: CD34+ cells in human intestine are fibroblasts adjacent to, but distinct from, interstitial cells of Cajal.[Show abstract] [Hide abstract]
ABSTRACT: Interstitial cells of Cajal (ICC) generate the pacemaker component of the gut and play important roles in the control of gut motility. The tyrosine kinase receptor Kit is an established marker for ICC. Recently, it has been reported that immunoreactivity for the sialomucin CD34 may be present on ICC in human intestine. Gastrointestinal stromal tumors express both Kit and CD34, suggesting that these tumors may derive from ICC. We characterized the distribution of CD34 immunoreactivity at the cellular level in the normal human gut, using double immunofluorescence immunohistochemistry and confocal microscopy. CD34 immunoreactivity identified previously unrecognized cells closely adjacent to, but distinct from, the Kit immunoreactive ICC. These CD34 immunoreactive cells expressed the fibroblast marker prolyl 4-hydroxylase-whereas ICC did not-and were also distinct from smooth muscle cells, glial cells, and macrophages. In the human gut, CD34 immunoreactivity is not expressed by ICC but by a population of fibroblasts, likely corresponding to the "fibroblast-like cells" described in previous ultrastructural studies. Our findings also challenge the hypothesis that stromal tumors originate from ICC.Laboratory Investigation 02/1999; 79(1):59-65. · 3.83 Impact Factor
Article: Calcium binding protein calcyphosine in dog central astrocytes and ependymal cells and in peripheral neurons.[Show abstract] [Hide abstract]
ABSTRACT: Calcyphosine is a calcium binding protein discovered in the dog thyroid in 1979. Calcyphosine mRNA and immunoreactivity were detected using Western and Northern blotting in the cerebral cortex, cerebral white matter and cerebellum. Using immunohistochemistry and in situ hybridization, both are present in ependymal cells, choroid plexus cells and several types of astrocytes of the subependymal cerebral layer, the cerebellar Bergmann layer, the retinal ganglion cell layer, the optic nerve and the posterior pituitary. Both are also present in neurons of nasal olfactory mucosa, enteric Auerbach and Meissner plexuses, orthosympathic and spinal cord ganglia as well as in endocrine cells of neural crest origin in the adrenal medulla. Calcyphosine immunoreactive astrocytes were also present mainly in hemispheric cerebral gray and white matter, hemispheric subcortical structures, brain stem and spinal cord. These results show that calcyphosine is a characteristic calcium binding protein of astrocytes and ependymal cells in the central nervous system and of neurons in the peripheral nervous system. This is of interest in view of the importance of calcium regulation in these cells, and since calcyphosine a calcium binding protein phosphorylated by cAMP dependent process, may be an intermediate between cAMP and inositol phosphate cascades.Journal of Chemical Neuroanatomy 11/1998; 15(4):239-50. DOI:10.1016/S0891-0618(98)00049-0 · 2.52 Impact Factor
Article: Keeping up with the Cajal rhythm.Nature Medicine 08/1998; 4(7):765-7. DOI:10.1038/nm0798-765 · 28.05 Impact Factor
Article: Modulation of the voltage-gated sodium current in rat striatal neurons by DARPP-32, an inhibitor of protein phosphatase.[Show abstract] [Hide abstract]
ABSTRACT: DARPP-32 is a cyclic adenosine monophosphate-regulated inhibitor of protein phosphatase 1, highly enriched in striatonigral neurons. Stimulation of dopamine D1 receptors increases phosphorylation of DARPP-32, whereas glutamate acting on N-methyl-D-aspartate receptors induces its dephosphorylation. Yet, to date, there is little direct evidence for the function of DARPP-32 in striatal neurons. Using a whole cell patch-clamp technique, we have studied the role of DARPP-32 in the regulation of voltage-gated sodium channels in rat striatal neurons maintained in primary culture. Injection of phospho-DARPP-32, but not of the unphosphorylated form, reduced the sodium current amplitude. This effect was similar to those induced by okadaic acid, with which there was no additivity and by tautomycin. Our results indicate that, in striatal neurons, sodium channels are under dynamic control by phosphorylation/dephosphorylation, and that phospho-DARPP-32 reduces sodium current by stabilizing a phosphorylated state of the channel or an associated regulatory protein. We propose that the DARPP-32-mediated modulation of sodium channels, via inhibition of phosphatase 1, contributes to the regulation of these channels by D1 receptors and other neurotransmitters which influence the state of phosphorylation of DARPP-32.European Journal of Neuroscience 05/1998; 10(4):1312-20. DOI:10.1046/j.1460-9568.1998.00142.x · 3.67 Impact Factor
Article: Postnatal development of interstitial cells of Cajal: Kit immunoreactivity studied by confocal microscopy on whole mounts of mouse intestine and colon.Gastroenterology 04/1998; 114(4). DOI:10.1016/S0016-5085(98)83715-3 · 13.93 Impact Factor
Article: Effect of sensory deafferentation on the GABAergic circuitry of the adult cat visual system.[Show abstract] [Hide abstract]
ABSTRACT: The effect of bilateral central retinal lesions on the GAD67 and GAD65 messenger RNA levels in the dorsal lateral geniculate nucleus, the perigeniculate nucleus and the visual cortex of the adult cat was investigated by in situ hybridization. Three days post-lesion, a decrease in the number of GAD67-expressing cells was apparent in the deafferented dorsal lateral geniculate nucleus. This decrease persisted until 7.5 months post-lesion and was more pronounced with longer survival times. The decrease in GAD67 mRNA was mirrored by a decrease in glutamate decarboxylase-immunoreactive cells. GAD65 messenger RNA expression levels were low in the dorsal lateral geniculate nucleus of both control and retinally-lesioned cats. In the perigeniculate nucleus the messenger RNA levels of both glutamate decarboxylase isoforms were clearly decreased over a restricted region. In the lesion-affected visual cortex, no changes at the messenger RNA level were observed for either GAD67 or GAD65 although changes in glutamate decarboxylase immunoreactivity have been previously described. Hence, in the dorsal lateral geniculate nucleus, the perigeniculate nuclcus and the visual cortex, different intracellular mechanisms seem to lead to decreased GABAergic inhibition in response to sensory deafferentation.Neuroscience 04/1998; 83(2):381-91. DOI:10.1016/S0306-4522(97)00422-3 · 3.33 Impact Factor
Article: Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor.[Show abstract] [Hide abstract]
ABSTRACT: Adenosine is released from metabolically active cells by facilitated diffusion, and is generated extracellularly by degradation of released ATP. It is a potent biological mediator that modulates the activity of numerous cell types, including various neuronal populations, platelets, neutrophils and mast cells, and smooth muscle cells in bronchi and vasculature. Most of these effects help to protect cells and tissues during stress conditions such as ischaemia. Adenosine mediates its effects through four receptor subtypes: the A1, A2a, A2b and A3 receptors. The A2a receptor (A2aR) is abundant in basal ganglia, vasculature and platelets, and stimulates adenylyl cyclase. It is a major target of caffeine, the most widely used psychoactive drug. Here we investigate the role of the A2a receptor by disrupting the gene in mice. We found that A2aR-knockout (A2aR-/-) mice were viable and bred normally. Their exploratory activity was reduced, whereas caffeine, which normally stimulates exploratory behaviour, became a depressant of exploratory activity. Knockout animals scored higher in anxiety tests, and male mice were much more aggressive towards intruders. The response of A2aR-/- mice to acute pain stimuli was slower. Blood pressure and heart rate were increased, as well as platelet aggregation. The specific A2a agonist CGS 21680 lost its biological activity in all systems tested.Nature 09/1997; 388(6643):674-8. DOI:10.1038/41771 · 42.35 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Infantile hypertrophic pyloric stenosis (IHPS) is a common surgical affection of unknown etiology. The muscular hypertrophy is known to resolve within a few months after pyloromyotomy (PM). The pathology of IHPS has been studied extensively at the time of PM, but the fate of the pylorus after healing remains unknown. We had the rare opportunity to study two pyloric biopsy specimens obtained 4 months and 2 years (respectively) after an uncomplicated PM for IHPS. They were compared with the initial specimen in one case, with 26 other specimens of IHPS, and with five normal controls. Immunohistochemistry using the avidin-biotin complex (ABC) system was performed for S-100 and nerve growth factor receptor, as markers for the enteric nervous system, and for the tyrosine kinase receptor c-kit, as a marker for the interstitial cells of Cajal (pacemaker cells). NADPH-diaphorase histochemistry was performed as a marker for the neuronal enzyme nitric oxide synthase, which produces the inhibitory neurotransmitter nitric oxide. In both cases of IHPS, after healing, the circular musculature was not hypertrophic. For all markers studied, the distribution appeared similar to that in the normal pylorus. In contrast, all specimens obtained at the time of PM displayed a severe reduction of the different markers in the hypertrophic musculature. The pathological features observed in the circular layer in IHPS appear to resolve within a few months after PM. This suggests that the involvement of the enteric nervous system in IHPS might be milder than generally assumed. The etiology remains obscure, but our occasional observations may provide new insight into the pathophysiology of IHPS, and are in agreement with the excellent longterm clinical outcome for IHPS.Journal of Pediatric Surgery 12/1996; 31(11):1530-4. DOI:10.1016/S0022-3468(96)90171-2 · 1.31 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Subpopulations of interstitial cells of Cajal are regarded as the source of spontaneous slow waves of the gut musculature (pacemaker cells). Their ontogeny remains unclear, but a role of the tyrosine kinase receptor c-kit in their development has recently been recognized. This study examined the interstitial cells in the human colon and in Hirschsprung's disease (aganglionosis). The distribution of the c-kit receptor was studied using specific antibodies in 5 normal patients, 10 patients with Hirschsprung's disease, and 3 patients with diversion loop enterostomies. c-kit immunohistochemistry was also combined with reduced nicotinamide adenine dinucleotide phosphate diaphorase histochemistry or with c-kit ligand (stem cell factor) immunohistochemistry. Transmission electron microscopy was performed in 1 patient with Hirschsprung's disease. c-kit immunoreactivity labeled a network of interstitial cells at the outer edge of the submucosa, in the muscular layers, and around the myenteric plexus. In aganglionic segments, interstitial cells were scarce and its network appeared disrupted. Interstitial cells of Cajal were identified in aganglionic regions by electron microscopy. Interstitial cells of Cajal are identifiable in newborns and exhibit similar distribution in diversion loops independent of contact with luminal nutrients. Our morphological data may explain the abnormal spontaneous electrical activity in aganglionic segments of Hirschsprung's disease and may give new insight into the ontogeny of interstitial cells.Gastroenterology 10/1996; 111(4):901-10. DOI:10.1016/S0016-5085(96)70057-4 · 13.93 Impact Factor
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ABSTRACT: The interstitial cells of Cajal form a network in close association with the smooth muscle of the gut. They are regarded as pacemaker cells and might be involved in motility disorders. Their distribution was studied in a common disorder with a dysfunction of the pyloric sphincter called infantile hypertrophic pyloric stenosis. Specimens from 27 infants with pyloric stenosis and 12 controls were processed for immunohistochemistry using a specific antiserum raised against c-kit, a tyrosine kinase receptor expressed by interstitial cells. In the normal pylorus, numerous interstitial cells were labeled throughout the tissue. In pyloric stenosis, c-kit immunoreactivity was absent in the major part of the tissue. Interstitial cells were observed only in the inner part of the musculature, near the submucosal edge, and in the antrum, at the proximal end of the biopsy specimens. The lack of interstitial cells in the pylorus possibly contributes to the motility disturbance of infantile pyloric stenosis.Gastroenterology 09/1996; 111(2):279-88. DOI:10.1053/gast.1996.v111.pm8690192 · 13.93 Impact Factor
Article: NMDA receptor antagonist MK-801 down-regulates rat striatal proenkephalin and protachykinin mRNAs.[Show abstract] [Hide abstract]
ABSTRACT: Using quantitative in situ hybridization, a significant decrease in expression of proenkephalin (27.1%) and of protachykinin mRNAs (20.0%) is observed in the rat caudate-putamen 14 days after daily intraperitoneal administration of N-methyl-D-aspartate receptor antagonist MK-801, 2 mg/kg.Neurochemistry International 03/1996; 28(2):189-92. DOI:10.1016/0197-0186(95)00070-4 · 2.65 Impact Factor
- Archives de Pédiatrie 02/1996; 3 Suppl 1:287s-291s. · 0.41 Impact Factor
Article: L'oxyde nitrique (monoxyde d'azote), le système non adrénergique-non cholinergique et la motilité digestiveArchives de Pédiatrie 01/1996; 3:S287–S291. DOI:10.1016/0929-693X(96)86070-2 · 0.41 Impact Factor
Article: Homolateral cerebrocortical changes in neuropeptide and receptor expression after minimal cortical infarction.[Show abstract] [Hide abstract]
ABSTRACT: A cortical infarct of 2 mm diameter was obtained in the parietal cortex after a craniotomy, disruption of the dura mater and topical application of 3 M KCl. It has been shown previously that the presence of a small cortical infarct induces an increase in immediate early gene messenger RNA expression followed by an increase in neuropeptide and glutamic acid decarboxylase messenger RNA expression. Glutamate, acting at N-methyl-D-aspartate receptors, is held responsible for these changes, since they are blocked by pretreatment with dizocilpine. In the present study, we have analysed the consequences of the dramatic changes in messenger RNA expression on the level of immediate early gene products c-fos and zif 268, and on that of neuropeptides by using immunohistochemistry. After just 1 h, an increase in c-fos- and zif 268-like immunoreactivity is observed in the entire cortical hemisphere homolateral to the infarct, and is no longer detected after 6 h. An increase in cholecystokinin octapeptide-, substance P-, neuropeptide Y- and somatostatin-like immunoreactivity is observed in the entire cortical hemisphere homolateral to the infarct after three days, and is no longer detected after 30 days. To investigate if these dramatic increases in neuropeptide immunoreactivities may have functional consequences, we studied the level of cholecystokinin receptors by autoradiographic binding using [125I]cholecystokinin-8S and in situ hybridization for the detection of cholecystokinin-b receptor messenger RNA. A decrease in cholecystokinin binding sites and cholecystokinin-b receptor messenger RNA is observed in the entire cortical hemisphere homolateral to the infarct after three days, and is no longer detected after nine days. This study shows that a topical stimulation has diffuse effects, reaching regions far from the site of the lesion, and some of them are still strongly present after nine days. The increase in neuropeptide messenger RNAs is followed by an increase in the protein products of these genes, which may modify the neurotransmission. As a corollary to this, a decrease in cholecystokinin binding sites occurs. This may have further consequences on signal transduction pathways. This decrease in cholecystokinin binding sites is associated with a decrease in the cholecystokinin-b receptor messenger RNA, and this is the first example of a decrease in messenger RNA levels in this experimental model.Neuroscience 01/1996; 69(3):847-58. DOI:10.1016/0306-4522(95)00277-P · 3.33 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: We studied the effect of intracavernous oxygen tension on the alteration of cavernous smooth muscle fibers in potent and impotent men. Intracavernous oxygen tension (mm. Hg) was measured during flaccidity and 10 minutes after intracavernous prostaglandin E1 injection in psychogenic control patients, and those with venous leakage and arterial lesions. Cavernous biopsies were performed and the percent of smooth muscle fibers was analyzed objectively using immunohistochemical actin anti-actin staining. Simultaneously brachial oxygen tension (mm. Hg) was measured and the cavernous brachial oxygen tension index was then determined. At flaccidity no significant difference was noted in oxygen tension values among the 3 groups of patients. After prostaglandin E1 injection cavernous oxygen tension and the cavernous brachial oxygen tension index in the control group were significantly different (p < 0.01) from those of the venogenic and arteriogenic groups (p < 0.01). The mean percent of cavernous smooth muscle fibers in the control group was significantly different from those of the venous leakage and arterial lesion groups (p < 0.01). There was a good correlation between the percent of cavernous muscle fibers and the value of oxygen tension before (p < 0.05) and after prostaglandin E1 injection (p < 0.01). A similar correlation was noted between cavernous muscle fibers and cavernous brachial oxygen tension index in the different groups of patients (p < 0.01). Reduction of the intracavernous smooth muscle fibers in impotent patients could be explained by low intracavernous oxygen tension.The Journal of Urology 12/1995; 154(5):1736-9. DOI:10.1016/S0022-5347(01)66772-7 · 3.75 Impact Factor
Top Journals
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Université Libre de Bruxelles
Bruxelles, Brussels Capital Region, Belgium
- Faculty of Medicine
Hôpital Universitaire des Enfants Reine Fabiola
Brussels, BRU, Belgium
- Department of Pediatric Surgery
Vrije Universiteit Brussel
Bruxelles, Brussels Capital, Belgium
- Institute of Interdisciplinary Research (IRIBHM)
Case Western Reserve University School of MedicineCleveland, Ohio, United States
University-Hospital Brugmann UVCBruxelles, Brussels Capital Region, Belgium
Northeast Ohio Medical UniversityRavenna, Ohio, United States
Harvard UniversityCambridge, Massachusetts, United States
University Hospital Brussels
Bruxelles, Brussels Capital Region, Belgium
- Department of Psychiatry
Catholic University of LouvainWalloon Region, Belgium
Karolinska Institutet
Solna, Stockholm, Sweden
- Department of Neuroscience


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Salad Cones
26 Jul 2010
|Soft white bread slices
|1 1⁄2 Pound (From 1 Loaf)
|1⁄2 Cup (8 tbs), softened
|Chicken salad/Margarine
|1⁄2 Cup (8 tbs)
1 Trim crusts from thin-sliced soft white bread; flatten each slice with rolling pin; spread to edges with softened butter or margarine.
2 Spoon 1 1/2 tablespoons chicken salad in center; fold bread diagonally; press edges to form cones.
3 Arrange in single layer on a foil-lined tray.
Mix 2 cups minced cooked chicken, 1/2 cup minced toasted almonds, 2 tablespoons minced parsley, 4 teaspoons lemon juice, 1/2 teaspoon salt, 1/2 teaspoon curry powder, and 1 cup dairy sour cream in bowl.
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Salad Cones Recipe


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Although older people who sustain a hip fracture are at increased risk of death and suffer long term disability throughout the world, the report indicates that this problem is far more severe in the Russia Federation and in many other countries of the region. Professor Olga Lesnyak, Vice-President of the Russian Association on Osteoporosis and author of the report, called for action, "There is an urgent need for health care providers to improve post hip fracture surgical care, "she said. While in Western Europe most hip fracture patients receive operative treatment (the optimal standard of care), in the Russian Federation there is an extremely low rate of surgical treatment. Consequently there is high mortality rate after a hip fracture, reaching up to 45-52% during the first year after fracture in some Russian cities. Of the surviving hip fracture patients, 33% remain bed-ridden and 42% are capable of only very limited activities. Only 9% are able to return to the same level of daily activity as they had before their fracture.
IOF Chief Operating Officer Judy Stenmark stated, "Wider and more equitable access to diagnostic tests and appropriate medication are required to stem the growing tide of fractures in the region."
|Contact: J. Stenmark
International Osteoporosis Foundation


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Twins open Target Field with college game
Mar 27, 2010, 9:04 PM EDT
The Twins opened brand new Target Field Saturday with a college game between the University of Minnesota and Louisiana Tech.
More than 37,757 showed up to take in the new ballpark, which features a massive fire pit in left field and several in-stadium bars and restaurants. Stuart Groskreutz wrote a review of the place for the Stillwater Gazette last week and there's a picture of today's action available on SBNation's Twinkie Town.
The Twins are hoping the new park, which looks like it could be a real gem, will provide enough revenue to justify the massive eight-year, $184 million contract extension that was handed to catcher Joe Mauer last weekend. So far, so good.
"The number one word we heard from people today was, 'incredible,"'
Twins spokesperson Kevin Smith told the Associated Press Saturday.
Oh, and for those interested in such things, Louisiana Tech won Saturday's game 9-1.
- cowdisciple - Mar 27, 2010 at 9:18 PM
Incredible is accurate, especially after a baseball lifetime in the Metrodome. Very cool to get a $2.00 general admission ticket and wander all over the place.
–One of the 37,757
- cowdisciple - Mar 27, 2010 at 9:19 PM
Incredible is accurate, especially after a baseball lifetime in the Metrodome. Very cool to get a $2.00 general admission ticket and wander all over the place.
–One of the 37,757
Captcha: for eggnog
- Old Gator - Mar 27, 2010 at 10:55 PM
Glad they got a nice day for it, but when El Nino powers down next year it'll be thermodynamic business as usual up in the Boreal zones. I think the right place for that fire pit will be under the seats by then. Warm isn't something you want to watch from a distance when you're freezing your ass off.
- cowdisicple - Mar 27, 2010 at 11:19 PM
I spend the winters here fishing for lake trout in the Boundary Waters at -35. 30 degrees feels BALMY, especially this time of year. If it's warm enough to play, me and my kindred spirits will fill the place up and be perfectly comfy.
- Pete - Mar 28, 2010 at 1:17 AM
That's one thing those below the Mason-Dixon line just aren't able to understand, through no fault of their own. After four months of weather where double digits below zero is just a fact of life, temps above freezing are great for us here in Minnesota. Throw on an extra layer and go to the game! Now, the same 50 degrees in July would be ridiculous, but that's unlikely.
- okobojicat - Mar 28, 2010 at 2:47 AM
I was also one of the 37,757 though I very much doubt more than 10,000 were ever in the stadium at more than one time. Most people came in for the $2 and then left about two innings later, just to get a peak around.
And the Gophers didn't look all that good out there.
- Drew Silva - Mar 28, 2010 at 2:51 AM
I'm loving the first-hand accounts, fellas. Thanks.
- Lard - Mar 28, 2010 at 9:20 AM
I didn't make it down to the game yesterday, but they had an open house for season ticket holders last weekend. The ballpark is simply fantastic (I particularly like the great wood backed seats in the club level, alas, I'll never be able to afford to sit there). As for the weather, as the guys above me already stated, 40-50 degrees in April is plenty warm after we've been subjected to a long cold winter.
Plus the forecast is for 70's this week. Maybe it will hold on until April 12 when they officially open the ballpark.
- Old Gator - Mar 28, 2010 at 11:43 AM
You're right, our ignorance of the joys of frostbite and hypothermia are not our fault. We're all born with a certain amount of glycol in our bloodstreams, but if we're not kept refrigerated – and worse, if we have fresh air, sunshine and watch them play two (did I just give away my age?) it turns to beer and leeches out of us, you know how. And whereas we can't speak with any authority about multiple skiens of double digit below-zero temperatures, we can view the political landscape down here as pretty substantial evidence of double-digit IQs.
I've actually been to Minnesota in the summer. If it's warm enough for Blandings Turtles, I suppose it'll support an open air population of baseball fans – something else with which most of the population of Macondo apparently has little or no famkiliarity. It's April and September, much less October (or well into November if you have to keep finding ways to thaw the field out in the postseason) that concerns me. And it's not even those natives with Norwegian and Swedish genes I worry about; a couple of slugs of Aqavit and to hell with glycol; they could sit through a Bergman festival in polo shirts in their convertibles in January at the local drive-in and probably do. But the spectacle of a stadium half full of freeze-dried out of town fans with Ted Williams commemorative cracks in their heads would not be pretty, even with Tim McCarver to describe it.
All that notwithstanding, keep that zodiac tethered near your front porches, try to stay dry up there and keep back from the edge of the creek creek until May.
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President Barack Obama's first few days in office have been interesting, to say the least. He sure has hit the ground running — but he's soon discovering that there are obstacles in the way. And some are in his path to purposely slow him down.
You can't say Obama hasn't tried to tackle everything in his first few days: from closing Gitmo, to talking with generals about how best to wind down our troops' involvement in Iraq, to scaling the Mount Everest of problems: the economic stimulus package.
So what to do with those nasty "they want to take away our freedoms" detainees at Guantanamo Bay, Cuba? Some of them haven't had a trial. So be it. But, if Gitmo closes, where do we put them? First choice: Crawford, Texas, where they can help W. clean brush and do Texas manly things. He created the problem, let him deal with it. They could put electricfied barb wire around the Bush compound and on a daily basis former Vice President Dick Cheney can ride horseback with a shotgun in case he has to shoot one of them in the face.
Fox News keeps having hissy fits about Gitmo. And at least for the first 24 and 48 hours they were trying to convince themselves and anyone else with half a brain who follows their every word that Obama was not legally the president because Chief Justice John Roberts screwed up the wording during the oath-takin.' Never mind that the Constitution states that Obama was officially and legally president as of noon on Jan. 20th — oath screwed up or not. But that wasn't good enough for Rupert Murdoch's minions — they probably wouldn't be satisfied unless the munchkin coroner from "The Wizard of Oz" made it official:" He's not only, nearly president, he's very, clearly president."
Now, to play it safe, Obama was sworn in by Roberts again the next day in a private ceremony. The second-time-around oath-takin' was only viewed by a few and audio and still photos were released for living history sake. Not good enough over at you know where: they didn't see Obama swearing on a Bible. So maybe during the first time Obama hypnotized Roberts into screwing up so he'd have an excuse to take the oath a second time without a Bible present. Paranoia can destroy ya. The next thing you know, the Fox hounds will be trying to make something out of the fact that our new president's initials are B.O.
Meanwhile, there's a Web site that's tracking the 510 — that's the number they're giving — promises Obama made during his two-year campaign to become president. That's keepin' a politician honest. So far it's two down and 508 to go. Now to the opposite of honest, conservative talk show megamouth Rush Limbaugh says he has four words for the new president: "I hope he fails." What an American. But then ol' Rush-to-judgment never gets behind anybody — because this load would still be in the picture.
Life imitating art:
Just in time to celebrate the Oscar nominations, some movie versions that wouldn't be mentioned in any category:
"The Good, the Bad Hair and the Ugly Press Corps": In his latest incarnation, Illinois Gov. Rod Blagojevich likened his political turmoil to that of an old cowhand from the Rio Grande in the Old West — using as a muddled metaphor the fact that his critics and the press are lynching him before he can get a fair trial. Blago went on a tangent that abused an already confusing and obscure example. Without going into detail because it was actually ignorant, suffice it to say that his example resembled one of those obnoxious questions on a college exam that boggles the mind for an answer. Such as, like: If a train leaves the station at 10:40a.m. and two cars traveling north and south on inter-connecting freeways pass each other going in opposite directions at 65 mph at 10:56 a.m., what time does the 9:51 a.m. flight from Fresno pass the train going at the speed of light?
Meanwhile, Blago is making the news rounds Monday, including "The View," to take his case to the people — uh, the townfolk of Tombstone territory.
The cost of Barack Obama's vacated Senate seat: let's talk about what's in it for me.
The cost of Elizabeth Hasslebeck asking Blago questions: Priceless.
"The Curious Case of Caroline Kennedy": What happened to JFK's daughter and Hillary's vacated Senate seat in New York? Caroline, no. Rumors were flying she got wind that N.Y. Gov. David Paterson wasn't going to name her, so she bowed out to save face. Other gossip growing on the grapvine suggests that Caroline has nanny problems, tax issues and marital woes. She may be having an extramarital affair. What, a Kennedy? Could be Caroline's a cougar. Why not, they call her Uncle Teddy the lion of the Senate. In any event, she pulled out of the running. Funny that, because a Kennedy's never been known to pull out of anything.
"Last Chance Harvey Milk": Dustin Hoffman, beginning to show his age, wanders off into the wrong movie — not the one with him and Emma Thompson, but the biopic of gay rights activist Harvey Milk. Hoffman then exposes the fact that Sean Penn is stealing his Ratso Rizzo voice from "Midnight Cowboy." Not the first time Penn borrowed heavily from Hoffman. In "I Am Sam," Penn, playing a mentally-challenged man, sounded an awful lot like Hoffman's autistic savant Raymond Babbit in "Rain Man." And Penn, like Hoffman, will probably win his second best actor Oscar. Got Milk?
"The (Weekly) Reader": No, not a Kate Winslet vehicle, but the story about the school newspaper of the United States offering personal ads in the publication. A two-fold purpose here: One, newspapers are struggling and the advertising is necessary. And two, ads make it easier for teachers to find out who is available for extra-curricular activities.


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Gear Review
Kim Havell
An Expedition Expert Tent
This tent stood up to the test on the Baltoro Glacier in Pakistan at 16,300ft this past summer. Phenomenal tent for base camp that is easy to assemble with a group of four plus folks, and resilient to all the elements. Great windows & double door protection (with fly), along with several pockets/sleeves for storing gear. Good floor that is very strong and withstands climbers' abusive tred. Shape allows for easy snow shedding and size is perfect for hanging out. We fit eight plus folks and extra gear and communications in this tent comfortably. The tent had no issue with hot to cold, and ventilates very well with the 2 doors & 2 windows unzipped. This tent is not wanting in any way, and the designers have covered everything you need in this product.
Great looking tent, but at 47 lbs, that's quite a load to carry on foot for a week from Askole. I assume it breaks into three parts of, what, 15 pounds? I'd also love to know what packs people chose for the trip.
Kim Havell
Hi Alaska Barb, sorry for a year delayed response. Just saw this comment via the new tool on this site. Yes, it splits up into 3 different loads. I don't own it so I have to double check but I think you are more or less right. We had porters carry it to our base camp so it is heavy but for a big team , it was very worth it.
We all used different packs. The TNF folks used their specific packs and I am an Osprey athlete so I use the Variant and the Ariel for trips like this now.
Hope that helps..almost a year later! :)
View More Details on The North Face 2-Meter Dome Tent: 8-Person 4-Season


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Easter Bunny Plastic Canvas Pin
By: Mary Cosgrove for Kreinik
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Make a plastic canvas pin to wear or give this Easter with a little bunny rabbit and a colorful butterfly. This plastic canvas Easter pin is made in bright thread colors for spring including Lavender and Tangerine.
- Quick-Count® 10-ct plastic canvas by Uniek
- Kreinik Heavy (#32) Braid: 008 Green, 092 Star Pink, 100 White
- Kreinik 1/8" Ribbon: 053F Lime
- DMC embroidery floss: 209 Dk Lavender, 741 Med. Tangerine
- Fabri-Tac™ Permanent Adhesive by Beacon™
- Whimsy Glass Bead by Wichelt Imports: one turquoise blue (#5013)
- scissors
- plastic canvas needle (No. 18)
- backing material: fabric, perforated paper, card stock, etc.
- pinback
- Cut canvas according to graphs, and as follows:
BASE: 18 x 18 holes
BACKGROUND: 16 x 16 holes
BUNNY: 9 x 12 holee
BUTTERFLY: 6 x 6 holes
- Using three strands of DMC Dark Lavender, work the background piece completely in cross stitches. Overcast the edges with Dark Lavender, using two stitches per hole.
- Work the bunny in Kreinik #32 Braid Star Pink in continental stitches. Overcast edges of bunny with #32 Braid in White.
- Holding background piece like a diamond, tack bunny to background, 3/8" from the top corner and 1/2" from the left corner, with #32 Braid in White, over existing stitches on left ear and bottom edges.
- Using three strands of DMC Medium Tangerine, work butterfly in cross stitches. Overcast the edges with Medium Tangerine, using 2 stitches per hole. Tack the center of the butterfly to the right corner of the background with 1/8" Ribbon Lime.
- Using three strands DMC Dark Lavender, whipstitch background to unstitched base, leaving one hole around all edges.
- Overcast edges of base with 1/8" Ribbon in Lime using 1 stitch per hole.
- Cut an 8-inch piece of #32 Braid Green. Glue with Fabri-Tac™ to background, below bunny, tacking at intervals while twirling/winding ribbon to make curly 'grass.' Glue turquoise blue Whimsy Glass Bead to head of bunny at (•) for an eye. Glue backing material to back of pin. Glue pinback to center of backing material.
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King & Wilson Essential Art Services works with museums, galleries and art institutions to coordinate packing and transport services for exhibitions and fairs, domestically and internationally.
We understand the demands placed on curators. Our company can assist and support you in navigating complex customs procedures and logistical challenges throughout the transport of your precious objects. With many years of experience behind us, our fine art team share an active interest in visual arts programmes.
King & Wilson Essential Art Services is a specialist in the analysis, evaluation, and organisation of major logistical movements, including collection relocations, household moves, and architectural project management. We have experience in working under some of the most difficult and challenging conditions and locations.
Recent fairs include; Hong Kong Art Fair, Armory Art Fair, Dubai Art Fair, Tokyo Art Fair, Art Stage Singapore, Taipei Art Fair, Brussels Art Fair, Art Basel, Auckland Art Fair and Melbourne Art Fair.


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1959 5C PR69 Deep Cameo PCGS....
2013 April 24 - 28 CSNS US Coin Signature Auction - Chicago #1184
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Renaissance Schaumburg Convention Center Hotel
1551 North Thoreau Drive
Schaumburg, IL 60173
|Printable auction results for all items in the 2013 April 24 - 28 CSNS US Coin Signature Auction - Chicago.
Impressive 1959 Nickel, PR69 Deep Cameo1959 5C PR69 Deep Cameo PCGS. As not only the grade suggests, but also the number of pieces graded at this level by the two major grading services, which stands at three combined, this coin is exceptional (3/13). The devices are richly frosted and the fields exhibit a strong degree of reflectivity. Faint, dappled sun-gold color appears throughout. The surfaces are pristine with the exception of two tiny specks. Population: 1 in 69 Deep Cameo, 0 finer (3/13).
From The Elite Cameo Collection.(Registry values: N1793) (NGC ID# 27A9, Variety PCGS# 94191, Base PCGS# 94172)
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Data place growth at UA 7th in nation
Posted: August 22, 2014 at 6 a.m.
The University of Arkansas at Fayetteville's growth in enrollment over a 10-year period ranks seventh nationally among public universities offering doctoral degrees, according to an analysis done by the Chronicle of Higher Education.
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Happy July 4th peeps! #fireworks #waaaaaahhhhhhh #'MericaDay
So proud of you my love!! And here we go!! #proudwifey #Repost @thatdanielwu with @repostapp. ・・・ Here we go! The first poster for Into The Badlands! Join me and my fellow costars on July 11th at comicon! #amc #comiccon #intothebadlands
Thank you so much perrinparis and karlaotto for this super chic glove clutch! Such a great idea. So… https://t.co/YTX4C78lKY
Thank you so much @perrinparis and @karlaotto for this super chic glove clutch! Such a great idea. So slick! #perrinparis #youcanneverhavetoomanyclutches
The bayou. A magical and eerie place. #nofilter #Nola #somanygators
Had my first #redlobster experience today. And I ain't mad at it! #cheapdate #cheapeats #livinlikeaballereatinlobsterinthemiddleoftheday #dangthatsalonghastag
Day 3, and final, project. Thanks rsalley for an amazing workshop. You are a great teacher!… https://t.co/zcjpzBjyfV
Day 3, and final, project. Thanks @rsalley for an amazing workshop. You are a great teacher! #thethreeringcircus #jewelryclass #feelinginspired @thomasmanndesign
Day 2 finished project from my "The Three Ring Circus" @rsalley workshop. #jewelry #jewelryclass #actuallymadethisfromscratch
Day 1 finished project in the @rsalley "The Three Ring Circus" workshop. So much fun! #jewelryclass #Nola #onedayiwillactuallysellmystuff
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Community: 12.19.08
Writing contest seeks submissions by Feb. 28
Texas Laughing Gull Writing Contest seeks submissions for prizes in fiction, non-fiction and poetry. All non-fiction entries also are eligible for the Port Aransas Heritage Prize. Submissions must follow the set guidelines and must be received by Feb. 28. The submission fee is $5. Winners will be announced in March and will be invited to read at the Laughing Gull Awards Reception in April 2009.
The winning entries will make up an anthology that will be sold at the awards reception and later at the Art Center for the Islands, Port Aransas. Guidelines/Information: email@example.com, or 361-749-7334, or download the guidelines from the events section of www.portaransasartcenter.org
Port Aransas poetry contest deadline is Jan. 30
The 2009 Emerging Writers Poetry Contest is seeking submissions of original poetry from high school students grades 9-12 (younger than 18). The contest is in conjunction with the annual Texas Laughing Gull Writing contest sponsored by the Art Center for the Islands in Port Aransas.
Submissions must be received by Jan. 30.
Guidelines/Information: Marilee at 361-749-0294 or firstname.lastname@example.com.
Corpus Christi Army Depot donates to Toys for Tots
Corpus Christi Army Depot recently presented a donation of assorted toys, bikes and $500 to representatives of the Marine Corps Reserve Center for its annual Toys for Tots campaign.
Verizon urges customers to recycle wireless phones
Verizon Wireless encourages wireless customers to recycle no-longer-used wireless phones, batteries and equipment in any condition from any wireless service provider through the company's HopeLine program. Old phones and accessories can be dropped off at Verizon Wireless Communications Store locations nationwide.
Phones collected by HopeLine will be used to provide a wireless phone to survivors of domestic violence.
Information: www.verizonwireless.com/hopeline
Health care workers give food to women's shelter
Corpus Christi Medical Center and Sodexo Health Care Services donated food to the Women's Shelter of South Texas on Dec. 15. The food will feed families staying at the shelter. Information: 761-5062.
County, Valero employees work to provide gift baskets
Board members of the Nueces County Community Initiatives Council and Adult Protective Services workers assembled gift bags at the Health Services Building, 4410 Dillon Lane, on Dec. 12. The baskets contained food, hygiene products and small clothing items that were donated to the council by Valero Refining employees.
Dr. Rhodes' book on pain treatment available online
Dr. Donald Rhodes of Corpus Christi has written the book "Pain Banishment, Not Pain Management" that describes how he has treated chronic pain and what led him into pain treatment. The book also explains the underlying causes of chronic pain, details his treatment methods, contains patient stories and his vision of pain banishment. The book is available on Amazon.com for $14.99. The first part of the book is available for free at Google Book Search. Information: 884-7079.
Girl Scouts collect items for Ronald McDonald House
Girl Scout Troop 9784 from the Calallen-Tuloso-Midway area delivered their community service items to the Ronald McDonald House, 3402 Fort Worth St., on Dec. 17. The community service project "Holiday Hope Drive" collected toiletries, games, clothes, jackets and school supplies for people staying at Ronald McDonald House.
CPS case workers receive new notebook computers
Region 11 Investigators with Child Protective Services, and staff from Adult Protective Services and Residential Child Care Licensing have received a newer advanced model of portable notebook style computer.
The new units are not only lighter but more compact in size and are packed with new features such as a larger hard drive and more memory and a mobile air card which will allow caseworkers to access the department's network while in the field. The staff, which includes workers in Alice, Aransas Pass, Bee, Corpus Christi, Kingsville and Sinton offices, also may use the Internet along with mapping software for geographical directions while working in the field.
Medical Center gives $4.4K to children's advocacy group
Nueces County Children's Advocacy will receive a $4,395.10 donation today from employees of Corpus Christi Medical Center.
For their recent Christmas party, staff from all departments assembled 72 holiday baskets for a silent auction among themselves to raise the funds. Two baskets sold for $350 each and three sold for more than $200 each.
The center was established in 1994 by the Child Abuse Council of South Texas with services to help sexually and severely abused children and their families in 12 counties in the Coastal Bend.
Valero golf tourney raises $369K for children's groups
Employees of the Valero Bill Greehey Refinery distributed $369,000 raised at the company's annual 2008 Valero Texas Open and Benefit for Children Golf Classic golf tournament held in San Antonio Oct. 5-10.
The 2008 Valero Benefit for Children recipients include:
• The ARK Assessment Center and Emergency Shelter For Youth
• Fighting to Rid Gangs in America Foundation
• Court Appointed Special Advocates (CASA) of the Coastal Bend
• Corpus Christi Police Athletic League
• Communities in Schools
• Boys and Girls Club of Alice
• Boys and Girls Club of Corpus Christi
• Boys and Girls Club of Kingsville
• Boys and Girls Club of Refugio
• Driscoll Children's Hospital
• Woman's Club of Aransas Pass
• Nueces County Children's Advocacy Center
• Rainbow Room (Nueces County CPS Community Partners)
• Kleberg County Child Welfare Board
• South Texas Council, Boy Scouts of America
• Corpus Christi Education Foundation
• South Texas Youth Development Corp.
• Bokenkamp Children's Shelter
• Spaulding for Children
• Woodsboro Eagle's Nest
• Girl Scouts of Greater South Texas
• Tennis Success
• Camp Aranzazu
• Big Brothers Big Sisters
• Avance
• Real Life Academy-Hannah's Hope
• Teen Challenge for Texas Coastal Bend
• Family Counseling Service
• Special Olympics
• Refuge of Hope
• Corpus Christi Housing Authority- Community for Youth Learning Center
• Sinton For Youth
-- Compiled by Tina Vasquez
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is this case compatible with the new IPhone 4S?
- Asked by Mary V from Massapequa Park
Michael Kors Wallet Clutch for iPhone 4/4S
Product No Longer Available
2 Answers from the Community
Best Answer:
Yes, This case is compatible with iPhone 4S. Both iPhones 4 & 4S are the same physical sizes.
- Answered by Alfredo L from Concord
Its beautiful, looks great, acts as bumper and card wallet ,not coind ,keys can be attached to wristlets..the only fall back..doesnt have a back hole for camera..kill joy!
- Answered by Nita G from Chomthong


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Originally written on Pro Sports Daily | Last updated 7/16/12
"I wanted to try something different," Everth Cabrera said Saturday night while explaining a play that major league baseball hadn't witnessed for 30 seasons. Cabrera was standing off third in the ninth inning Saturday night with the Padres down by a run and down to their final strike. When Dodgers reliever Kenley Jansen turned his back to the plate to clean the dirt out of his cleats, Cabrera took off for home. Not only did Cabrera steal home to tie the game, he drew a wild throw from Jansen that allowed Will Venable to follow him to the plate with the winning run. Cabrera's steal of home marked the first time in nearly 30 years that a major league team has won a regular-season game in which either the tying or go-ahead run scored on a steal of home in the ninth inning or later. According to the Elias Sports Bureau, the last time it happened was on Aug. 22, 1982. Cardinals catcher Glenn Brummer dashed home in the 12th inning, beating the pitch from Giants pitcher Gary Lavelle,...
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Press release from Marketwire
Northcore Enters Into Loan Agreement
Sunday, September 30, 2012
Northcore Enters Into Loan Agreement18:20 EDT Sunday, September 30, 2012TORONTO, ONTARIO--(Marketwire - Sept. 30, 2012) - Northcore Technologies Inc. (TSX:NTI)(OTCBB:NTLNF), a global provider of asset management and social commerce announced today that it has entered into a loan agreement with Pacific NA Financial Group Inc. The secured loan with a principal amount of CAD $500,000 has an interest rate of 8 percent and is payable on demand. Northcore develops solutions to support the evolving needs of industry and provides comprehensive platforms for the management of capital equipment and the implementation of Social Commerce business models. These products are proven, effective and in use by some of the world's most successful corporations.Companies interested in effective software solutions should contact Northcore at 416-640-0400 or 1-888-287-7467, extension 395 or via email at email@example.com news release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of securities in any jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such jurisdiction. About Northcore Technologies Inc. Northcore Technologies provides enterprise level software products and services that enable its customers to purchase, manage and dispose of capital equipment. Utilizing award-winning, multi-patented technology, as well as powerful, holistic Social Commerce tools, Northcore's solutions support customers throughout the entire asset lifecycle. Northcore's portfolio companies include Envision Online Media Inc., a specialist in the delivery of content management solutions and Kuklamoo, a family information web destination and national daily deal site targeting families with kids.Northcore has earned the trust and loyalty of customers from a wide range of organizations across many different industry sectors.Northcore owns 50 percent of GE Asset Manager, LLC, a joint business venture with General Electric Capital Corporation, and holds a substantial intellectual property portfolio.For more information, visit www.northcore.comThis news release may include comments that do not refer strictly to historical results or actions and may be deemed to be forward-looking within the meaning of the Safe Harbor provisions of the U.S. federal securities laws. These include, among others, statements about expectations of future revenues, cash flows, and cash requirements. Forward-looking statements are subject to risks and uncertainties that may cause Northcore's results to differ materially from expectations. These risks include the Company's ability to raise additional funding, develop its business-to-business sales and operations, develop appropriate strategic alliances and successful development and implementation of technology, acceptance of the Company's products and services, competitive factors, new products and technological changes, and other such risks as the Company may identify and discuss from time to time, including those risks disclosed in the Company's Form 20-F filed with the Securities and Exchange Commission. Accordingly, there is no certainty that the Company's plans will be achieved. Important factors that could cause actual results to differ materially from the Company's expectations are disclosed in the Company's documents filed from time to time with the Toronto Stock Exchange, on SEDAR (the System for Electronic Document Analysis and Retrieval at www.sedar.com) and the US Securities and Exchange Commission. This news release shall not constitute an offer to sell or the solicitation of an offer to buy securities of the Company in any jurisdiction.FOR FURTHER INFORMATION PLEASE CONTACT: Investor RelationsNorthcore Technologies Inc.(416) 640-0400 ext. 273(416) 640-0412 (FAX)firstname.lastname@example.com


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Poll: In your opinion, which of the following poses the biggest threat to the country: big business, big labor or big government?
Big business 24%
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Avril Lavigne
Born Sep 27, 1984 Age 30
Hometown Belleville, Ontario Net Worth $33.33 Million
Religion Christian Genres Pop rock + Altern...
Instruments Drums + Squier Te... Performed With Sum 41 + Chad Rob...
'Avril Ramona Lavigne is a Canadian singer-songwriter. She was born in Belleville, Ontario, but spent most of her youth in the small town of Napanee. By the age of 15, she had appeared on stage with Shania Twain; by 16, she had signed a two-album recording… Read More
View newly released photos of Avril Lavigne.
Check out the latest love interests for Avril Lavigne.
Chad KroegerMarried 2013 - Present
Brody JennerDated 2010 - 2012
Wilmer ValderramaDated 2009 - 2010
Justin MurdockDated 2009 - 2010
Brandon DavisDated 2008
Deryck WhibleyMarried 2006 - 2010
Doug RobbFling 2004 - 2005
Mitch AllanFling 2003
Jesse ColburnDated 2002 - 2003
Blake ThompsonDated 2001
Matt Kennedy GouldDated
Discover the family history of Avril Lavigne.
Avril Lavigne
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Judith-Rosanne LoshawFather
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Growing Threat Of Lyme Disease In A Hotter WorldYahoo News - May 04, 2015
Can Classical Music Be Cool?Huffington Post - Apr 13, 2015
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Avril Lavigne And Lyme Disease: Your Questions AnsweredABC News - Apr 01, 2015
Learn about the memorable moments in the evolution of Avril Lavigne.
1984 Birth Born on September 27, 1984.
2002 17 Years Old 5 More Events
… In 2002, when she was 17 years old, Lavigne broke onto the music scene with her debut album Let Go. … Read More
2003 18 Years Old 2 More Events
She won four Juno Awards in 2003 out of six nominations, received a World Music Award for "World's Bestselling Canadian Singer", and was nominated for eight Grammy Awards, including Best New Artist and Song of the Year for "Complicated" (2003).
2004 19 Years Old 4 More Events
Lavigne's second studio album, Under My Skin, was released on 25 May 2004, debuting at No. 1 in several countries, including Australia, Mexico, Canada, Japan, the UK, and the U.S. The album has sold more than 10 million copies. … Read More
2005 20 Years Old 1 More Event
She received five Juno Award nominations in 2005, and picked up three, including "Artist of the Year". … Read More
2006 21 Years Old 4 More Events
On 26 February 2006, Lavigne represented Canada at the closing ceremony of the Torino Olympics, performing her song "Who Knows" during the eight minute Vancouver 2010 portion.
2007 22 Years Old 3 More Events
Lavigne's third album, The Best Damn Thing, was released on 17 April 2007, which Lavigne immediately promoted with a small tour. … Read More
2008 23 Years Old 1 More Event
In March 2008, Lavigne undertook a world tour named The Best Damn Tour to support the album. … Read More
2009 24 Years Old 2 More Events
It was announced on 17 September 2009 that Lavigne and Whibley had split up and that divorce papers would soon follow.
2010 25 Years Old 12 More Events
In January 2010, while simultaneously writing and recording for her new album, Lavigne worked with Disney clothing designs inspired by Tim Burton's feature film, Alice in Wonderland. … Read More
2012 27 Years Old 4 More Events
She subsequently quietly began dating fellow Canadian rocker Chad Kroeger, frontman of the band Nickelback, in February 2012. … Read More
Original Authors of this text are noted on http://en.wikipedia.org/wiki/Avril_Lavigne.
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AMES, Iowa – Grazing management for water quality will be addressed in the upcoming Iowa State University webcast, "Grazing Management for Water Quality Protection." Professors from three ISU departments will be coming together to present the information. The Oct. 16 webcast will start at 1:30 p.m. Central time. Participants can download the speakers' PowerPoint presentations and connect to a virtual meeting room. This will allow them to listen to the presentations and participate in further discussion.
The ISU speakers will cover a variety of grazing management topics, focusing on maximizing production and adequately managing environmental risks to the pasture. Presenters will also discuss waterborne pathogens and ways to prevent their movement to water bodies. An application for continuing education credit for Certified Crop Advisers (CCAs) and members of the American Registry of Professional Animal Scientists (ARPAS) has been submitted.
Iowa State professors who will be presenting include James Russell, Department of Animal Science; Steve Ensley, Veterinary Diagnostic Laboratory; and Tom Isenhart, Department of Natural Resource Ecology and Management. Additional information about the webcast speakers is available at http://pubwiki.extension.org/mediawiki/files/8/8b/09oct_flyer.pdf .
To participate in the grazing management webcast, go to www.extension.org/pages/Live_Webcast_Information to connect to the virtual meeting room and download the speaker's PowerPoint presentations. First-time viewers should also follow the steps at www.extension.org/pages/How_Do_I_Participate_in_a_Webcast%3F . The presentations will be available for download the morning of the webcast and the virtual meeting room will open up approximately 15 minutes before the webcast begins.
James Russell, Extension beef specialist, (515) 294-4631, firstname.lastname@example.com
Taylor Gerling Shore, Iowa Beef Center, (515) 294-9124, firstname.lastname@example.com
Willy Klein, Extension Communications and External Relations, (515) 294-0662, firstname.lastname@example.com


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What is the PerfLevelSrc hack ?
View Single Post
Registered User
Join Date: Nov 2006
Posts: 79
Re: What is the PerfLevelSrc hack ?
Originally Posted by
However, even on a laptop Beryl will give those low-end cards a workout. I'll speak hypothetically and say that it is doing lots of up and down clocking, which maybe the driver is not 100% stable in doing it.
Yes, it is. And, no, the driver isn't always stable doing those frequency changes. That is in fact the way the PerfSrcLevel hack came into existence. The clock changes were causing machines to hang.
Originally Posted by
XID errors typically mean the driver received a hardware error. I normally see them when the cards are overheating or about to die (two have died when lots of XID errors started happening). Tweaking the driver to "reduce" XID errors is only delaying the inevitable.
No, you are wrong. Even if XID errors were caused by heat, that does not imply that the heat problem is because you are taxing the capabilities of the video card. It could be a driver problem, BIOS problem, ventilation problem, etc.
Originally Posted by
Yes, he will have to buy better hardware. Why are you so cheap? Spend an extra $100 and get a chip that is twice as fast, won't overheat, and will last you a while.
Why not try to get the performance that your card is obviously capable of without risking shortening it's lifespan? Having users throw money at a problem only allows vendors to continue to produce sub-par hardware and drivers. Buying a new card is the worst possible solution considering that his hardware is obviously capable of doing what he wants.
I also don't understand why you are calling me "cheap". A laptop is not a desktop. You can't just wander into a CompUSA and buy an upgrade for US$100. It's all or nothing. You buy a new laptop or live with what you have.
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Address: 65 Elmtree Road, , SUTTON COLDFIELD, B74 3RZ
Address: 84 Beacon Road , Rolleston on Dove , Burton on Trent, DE22 3JL
Address: 28 Belmont Terrace, , Shipley, BD18 3LY
Address: 8 Dryhurst Drive, Disley, , Stockport, SK12 2EH
Address: St Hughes Social Club, Derby Road, Borrowash, DE72
Address: Annex To The Grange Banqueting Suite, 457a Burton Road Littleover, DERBY, DE23 6XX
Address: 15 Leominster Road, Oakwood, Derby, DE22 1JU
Address: 4 Russet Close, Hatton, DERBY, DE65 5QR
Address: 16 Foley Road East, Streetly, Sutton Coldfield, B74 3JP
Address: 35a High Street West, , GLOSSOP, SK13 8AZ
Address: 110 East Street, Doe Lea, CHESTERFIELD, S44 5DL