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Ortiz, Red Sox top Rays in rainy twinbill openerBy DOUG ALDEN
the Associated Press | June 19,2013AP PHOTO
Bostons Jacoby Ellsbury makes the out on a fly ball by Tampa Bay Rays Wil Myers in the second inning of the first game of a baseball doubleheader in Boston, Tuesday. Boston won the first game 5-1.BOSTON David Ortiz drove in three runs and the Boston Red Sox opened a day-night doubleheader by beating the Tampa Bay Rays 5-1 Tuesday in a game delayed nearly three hours by rain.
The halt in the fifth inning lasted 2 hours, 59 minutes, prolonging a game that had already been postponed because of rain on April 12.
The Red Sox invited fans who stuck out Tuesdays first game to return for the second for free. The opener ended after the scheduled 7:05 p.m. start time for the nightcap by that point, with little turnaround time, Game 2 were already wandering into Fenway Park.
Highly touted Rays prospect Wil Myers went 0 for 4 in his major league debut. The 22-year-old rookie played right field.
Boston led 4-1 when the downpour began. The Red Sox added a run in the sixth on back-to-back triples by Jacoby Ellsbury and Shane Victorino.
Ellsbury also doubled and singled, and he scored all three times he reached base.
Alfredo Aceves (4-1) overcame early control problems and won his third straight start, allowing one run and three hits. He did not return after the delay.
The Red Sox had lost four of six, including two of a three-game series at Tampa Bay last week.
Chris Archer (1-3) took the only loss for the Rays last week, and Boston beat him again. He struck out five in 4 2-3 innings, but also walked five while allowing four runs and five hits.
Archer walked Daniel Nava to load the bases with two outs in the fifth and that was it for him. Josh Lueke came in from the bullpen and had just started warming up when the rain arrived and the game was delayed with Boston leading 4-1. Almost three hours later, Lueke struck out Jarrod Saltalamacchia to end the inning.
Ortiz hit a two-run single in the third after Ellsbury and Victorino opened the inning with singles.
NOTES: Red Sox 2B Dustin Pedroia was back in the lineup after sitting out Sunday in Baltimore. He had started the teams first 70 games this season. ... Boston 1B Mike Napoli also returned to the lineup after missing the past three games because of an illness. ... At 22 years, 190 days old, Myers became the youngest player to make his MLB debut in right field at Fenway Park since Bostons Dwight Evans did so at 20 years, 318 days on Sept. 16, 1972.MORE IN Wire SportsVANCOUVER, British Columbia. With the title match looming, Abby Wambach isnt mincing words. Full StoryWHITE SULPHUR SPRINGS, W.Va. Full StoryDAYTONA BEACH, Fla. Full Story
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- RICHARD'S POOR ALMANACK: On this day in 1472, Orkney, Shetland islands put up as collateral by Norway to Scotland in lieu of dowry for MARGARET OF DENMARK on her marriage with JAMES III, king of Scotland; 1962, JOHN GLENN first American to orbit Earth.
- TOMORROW'S HEADLINES TODAY: City mayoral candidates debate campaign issues; Hartford, Conn., woman still missing; Neal Goswami reports attempts to legislate suicide; local woman loses 100 pounds through TOPS program.
- RICHARD'S POOR ALMANACK: On this day in 1878, JOHN TUNSTALL murdered near Lincoln, New Mexico, by the outlaw JESSE EVANS; in 1930, ELM FARM OLLIE first cow to fly in aircraft, first to be milked airborne; 1955, nuke test WASP; '79, snow in Sahara.
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I have been leaning towards a home-made, semi raw diet for my dogs. I have been using less kibble and notice that my dogs look better.
So, I am thinking of taking it to the next level. Grinding raw chicken gizzards, necks, maybe chicken wings.
The Tasin-TS 108 electric meat grinder was recommended to me.
Has anyone tried this? Is it worth the bother? I'm getting a little tired of paying over $50 for a bag of kibble that may not be that great, nutrition wise.
Ps: Additional information: http://vitalanimal.com/kibble-dogs-only/

subset: commoncrawl


text: Quick View save 72% Marilyn Monroe: The Personal Archives by Carlton Books August 1, 2010 | Trade Paperback In stock online from $9.50 There is no more recognized actress of the twentieth century than Marilyn Monroe. She stared in some of the most popular films ever made and almost 50 years after her death she is still voted the sexiest woman of all time and the greatest female star of the twentieth century. Marilyn… See Details $10.00 / $9.50 lowest price*was $34.95


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Aston Martin, DBS, James Bond cool as James Todd
from Pusha T (Ft. Wale) – Only You Can Tell It Lyrics on Genius
James Bond the 007 Agent and James Todd Smith better known by his rap moniker LL Cool J are referred to here. He has both the style and skills of James Bond while being as cool as LL Cool J is
James Bond's car of choice is the Aston Martin. They're always feature in the 007 films
A 2012 Aston Martin DBS will cost you about 300k
To help improve the quality of the lyrics, visit Pusha T (Ft. Wale) – Only You Can Tell It Lyrics and leave a suggestion at the bottom of the page


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Flour Bluff is up to the task
Duo rallies Hornets past rival Lady Cats
CORPUS CHRISTI - Trailing district rival Gregory-Portland by a goal in the final minute of the first half on Friday, Flour Bluff's girls soccer team needed someone to step up — or else its season would come to an end at Cabaniss Field.
Someone did. The Hornets' 1-2 scoring punch of Kaitlyn Belew and Kaitlyn Kasperitis delivered three staggering blows in a matter of minutes to reverse Flour Bluff's playoff fortunes and guide it back into the Region IV-4A final for the second straight season.
Junior midfielder Belew and junior forward Kasperitis scored two goals each in the final 41 minutes of play to lift Flour Bluff to a 4-3 Region IV-4A semifinal victory over the Lady Cats.
"We're all really excited — we really want it," Kasperitis said of advancing to next week's Class 4A state tournament in Georgetown. "It's just a matter of winning our next game."
District 59-4A champion Flour Bluff (24-1), which has won 18 straight matches, moves on to play 2009 state semifinalist Boerne Champion (21-3-4) again in the Region IV-4A championship match at 1 p.m. today at Cabaniss Field. The Chargers — who beat regional semifinal opponent San Antonio Alamo Heights, 1-0, in a shootout Friday — knocked the Hornets out of last year's regional final, 2-0.
"We're just happy to be moving on," said Flour Bluff girls coach Mario Lopez, whose team defeated G-P two out of three meetings this season by the same score. "Boerne Champion has a good team, and we're in for a tough match."
The 59-4A runner-up Lady Cats (16-4-2), making their first regional semifinal appearance since 2007, fell despite G-P junior forward Jordan James' hat trick against the Hornets.
"It's tough, especially for our four seniors — they had high hopes of going all the way," Lady Cats coach Jaclyn Vasquez said. "We have a very talented team, but Flour Bluff proved to be better today."
The turning point came on Belew's goal off a line-drive free kick with 58 seconds remaining in the first half to tie the match at 1. Kasperitis then gave Flour Bluff the lead for good with a goal — on which junior forward Sydney Marr had an assist — off a breakaway 25 seconds into the second half.
Belew added her second goal of the match less than five minutes later to give the Hornets control.
"It's really satisfying to know that we could pull it off again (against G-P) and pull out a win," said Belew, who has combined with Kasperitis for 16 goals in this postseason.
Although James scored two of the next three goals — with Kasperitis scoring the other — in the match to bring the Lady Cats to within 4-3 in the final 12 minutes of play, it wouldn't be enough against Flour Bluff junior goalie Julia Eckardt, who made four saves in the match, and the Hornets' defense.
"We didn't panic when things weren't going our way," Lopez said. "G-P really made it difficult for us, but we stayed together, worked hard and things worked out (for us)."
Sophomore goalie Hannah McWilliams made two saves and had an assist for the Lady Cats.
"I'll have a very strong team next year (as well) and we'll be back," Vasquez said.
Goals — Flour Bluff, Kaitlyn Belew 2, Kaitlyn Kasperitis 2; G-P: Jordan James 3. Assists — Flour Bluff: Sydney Marr 1; G-P: Hannah McWilliams 1. Shots on goal — FB: 6, G-P: 7. Saves — FB: Julia Eckardt 4. G-P: McWilliams 2. Corner kicks — FB: 4. G-P: 4. Records — Flour Bluff, Overall, 24-1. G-P, 16-4-2.
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Santa Cruz's own Otayo Dubb brings blue collar hip-hop to the Lagoon
he name Otayo Dubb—a moniker taken from the Swahili term for "ambush"—connotes the effect of the rapper's blue collar hip-hop style. Straddling the underground hemispheres of street and conscious hip-hop, Dubb's musical ambush is a bumping meditation on the struggles and joys of everyday working-class people.
Though born in Oakland, Calif., Dubb was raised by two working-class jazz musicians on the west side of Santa Cruz. His hunger for rhythm was established before birth, as his mother, an avid musician of Caribbean and West African influence, played congas while pregnant with him.


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Guest bedrooms
Guests of the hotel can make use of the following room facilities: coffee/tea maker and phone. Bathroom amenities include complimentary toiletries. Housekeeping services are provided.
Hotel Facilities
Meal options at Adamton Country House Hotel include a restaurant. Daily breakfast is available for an additional charge. Our hotel provides a 24-hour front desk service. Additional hotel facilities: garden and tennis court(s). Additional services: concierge services, tours/ticket assistance and wedding services.
Hotel Services and Facilities
DiningEnjoy a satisfying meal at a restaurant serving guests of Adamton Country House Hotel. Quench your thirst with your favorite drink at a bar/lounge.
Hotel facilities
- Breakfast available (surcharge)
- Tennis on site
- Bar/lounge
- Restaurant
- 24-hour front desk
- Outdoor tennis courts3
- Concierge services
- Meeting rooms
- Tours/ticket assistance
- Free self parking
- Garden
- Arcade/game room
- Wedding services
- Free WiFi
- Conference space
- Pets allowed
Important information
- Children 2 years old and younger stay free when occupying the parent or guardian's room, using existing bedding.
- Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation (surcharges apply and can be found in the Fees section).
The following fees and deposits are charged by the property at time of service, check-in, or check-out.
- Pet fee: GBP 10 per pet, per night
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
Guest reviews
How to bookMaking your reservation in Adamton Country House Hotel is easy and secure. Simply select your dates of stay and click on the "Check Rates" button to submit the form.
After room types and rates are returned to your screen, you will be able to choose the rate you desire by reading the room information in the center of the screen, then clicking on the "Book Now" button on the right side of the screen. After you have selected your desired room type, you will be taken to a "Complete your booking" form. Then you will need to review the "Details of your stay" and fill in the blanks on the "Guest Details" section. Be sure your name and email address are spelled correctly.
After you fill out all of the needed information, press the "Complete reservation" button. To ensure your security, we use a secure commerce server, which encrypts the credit card number and encodes it into a non-usable form.
Area informationDistances are calculated in a straight line from the property's location to the point of interest or attraction, and may not reflect actual travel distance.
Distances are displayed to the nearest 0.1 mile and kilometer.
Royal Troon Golf Club - 5.5 km / 3.4 mi
Ayr Racecourse - 6.3 km / 3.9 mi
Auld Brig - 6.7 km / 4.2 mi
Ayr Town Hall - 6.9 km / 4.3 mi
Auld Kirk - 6.9 km / 4.3 mi
Wellington Square - 7.3 km / 4.5 mi
Pirate Pete's Family Entertainment Centre - 7.5 km / 4.6 mi
Ayr Pavilion - 7.5 km / 4.7 mi
Ayr Beach - 8.3 km / 5.1 mi
St. John's Tower - 9.7 km / 6 mi
Burns Cottage and Museum - 10 km / 6.2 mi
Robert Burns Birthplace Museum - 10.5 km / 6.5 mi
Tam o' Shanter Experience - 10.5 km / 6.6 mi
Rugby Park - 10.6 km / 6.6 mi
Alloway Kirk - 10.6 km / 6.6 mi
The nearest airports are:
Glasgow (PIK-Prestwick) - 2.7 km / 1.7 mi
Glasgow (GLA-Glasgow Intl.) - 39.7 km / 24.7 mi
The preferred airport for Adamton Country House Hotel is Glasgow (GLA-Glasgow Intl.).


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text:
Brangwyn's War: Posters of the First World War
30 Jun 2014 – 18 Jan 2015
Event times
Opening times: Tuesday-Saturday 10.00am-5.00pm; Sundays 2.00pm-5.00pm
Cost of entry
Free entry
AboutFrank Brangwyn was an outstanding poster artist of the First World War. A restored set of his powerful large-scale war posters is on show at the Mercer Art Gallery in Harrogate until January 2015. These images offer both a unique social insight into the propaganda of the period as well as reflecting the artist's personal concerns. This is the first time that the posters, all lithographs that have recently been cleaned and restored, have been displayed by Harrogate Arts and Museums. The posters were donated to the gallery by Harrogate artist and printmaker Oliver Pemsel and the exhibition is curated by Brangwyn expert Dr Elizabeth Horner.
Art form
Have you been to this event? What do you think? Join the discussion here!
Remember, you can include links to your instagram pictures and to videos.


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Dear Friends,
A week ago Sunday, we met with Ms. Kefah Akram, the new librarian at the Ibn Rush'd Library in Al Aqaba. Raheya Alsbaih, director of the Rural Women's Association, joined us as did Josie Shields-Stromsness who drove up from Bethlehem for our meeting. Josie is part of the Middle East Children's Alliance and works with a number of library projects in the West Bank, East Jerusalem, and Gaza.
This day, May 16th, was the 11th anniversary of Rachel Corrie's death in Gaza and we are here in this little village facing demolition orders on nearly all the buildings. We marked her anniversary by meeting to explore how to use the funds you've donated to best help children and youth through this wonderful library. We also used our meeting to develop our scholarship program for kindergarteners (but I'll leave that for a separate report). Al Aqaba is holding steady through their good work, your support, and everyone's intervention. I hope Rachel would be proud of our work.
Let me tell you more about our meeting and our follow-up visit the next day:
Just before our trip, Rebuilding Alliance's Board approved the transfer of a grant of $4,326 for the Ibn Rush'd Library. Half of this will cover Kefah's salary for the year, and the other half will be used to expand the wall of the library onto the covered porch to make the library bigger and include indoor access to the restroom. Mayor Haj Sami asked me to help make plans for Kefah's library training at the AlAnwar Children's Library in Hebron.
Do you remember that the Ibn Rush'd Library project has been accepted into Microsoft Youth Spark grant program? On April 16th there will be a Bonus Day with Microsoft matching 50% to each dollar donated — please mark your callendar.
It was really fun to use our meeting to brainstorm about the entrepreneurship program for young people that the Ibn Rush'd Library will be offering as part of the Youth Spark grant. The next day we went on a Field Trip to Canaan Fair Trade to help Librarian Kifah learn more about entrepreneurship by seeing how wonderfully successful Canaan has become. Founder Nasser Abufarha will be returning next month and would be pleased to host a group of students to tell them how he came up with the idea of Fair Trade Olive Oil and what it took to get this wonderful business started. Librarian Kifah asked a ton of questions and got to thinking about a list of speakers. She'll send us her plans soon.
We also noted that the computers in the library are not currently connected to the Internet, in part because the mayor is afraid that everyone will just be on Facebook, not doing any real learning. To overcome that fear, we proposed uploading the offline educational content offered by www.worldpossible.org
Lastly, we asked Librarian Kifah and Kindergarten Director Raheya Sbaih to become members of the Beyond Access organization in the hope they can receive scholarships to attend their annual international conference this year or next.
Thank you again for your incredible support. Again, please mark your calendar for April 16th and give as early as you can that day to benefit by Microsoft's 50% match.
Dear Friend,
Greetings from Jerusalem! Rebuilding Alliance's Accountant and Assistant Project Manager, Thai Hien Ho, and I arrived yesterday to a rainy, blustery, thunder-stormy Jerusalem.
Tomorrow we'll be meeting with the team at the UN's Office for Coordination of Humanitarian Affairs (UNOCHA) who wrote the newly released, "Area C Vulnerability Profile". As stated in the report, "An estimated 297,900 people live in 532 residential areas in Area C, comprising some of the most vulnerable communities in the West Bank in terms of humanitarian needs." (see attached link). If you've been looking at the West Bank via GoogleMaps, Area C looks so very empty — the villages have already disappeared. That's a problem we should be able to fix. With the help of a friend at Google, Thai and I will be conveying UNOCHA's data to the mapping team at Google so that those missing 532 residential areas including some 148 Palestinian towns will show up on Google's maps of the West Bank.
When I think about all that Rebuilding Alliance does, I feel that this project, the U.S. Movement to Save Palestinian Villages, is one of our most important. I'm delighted to report that we've used project funding to purchase a GPS camera and also MapAnything Software to help build the software app that will make it easier to contact congress. Here's what we plan to do on this trip:
1. We want the U.S. Movement to Save Palestinian Villages to build on our success in keeping one village, Al Aqaba, standing despite demolition orders issued on 97% of the village including nearly all the homes, the medical clinic and our kindergarten. What's worked is our collective engagement with congressional staffers who call the U.S. State Department and the Israeli Embassy at their constituents' request as soon as demolition bulldozers are on the move. We hope to meet with the American Consulate in Jerusalem to explore how to extend this to other at-risk villages;
2. We are in touch with Reverend Yoshii and the Friends of Wadi Foquin Village who are also visiting the area. Their congressional briefing was very successful but in January, the Israeli Army destroyed some 200 newly planted olive trees in Wadi Foquin. That's the type of destruction we hope can be avoided by developing a contact congress "early warning system" approach, much like we've done in Al Aqaba.
3. We're working with a group of UC Berkeley Computer Science Students who are part of a chapter called, "Code the Change" to develop better mapping tools for projects like this, both as a way to raise funds for construction and tree planting projects and also as a way to monitor progress over time and build advocacy to keep each project area safe too. Their prototype may be ready next month!
4. We look forward to meeting the legal team at Rabbis for Human Rights to hear about their lawsuit to assure villages in Area C to plan their future growth. Thai and I hope to meet with them to explore how we can focus U.S. attention on this important concept through our advocacy software.
Thank you again for your support of the U.S. Movement to Save Palestinian Villages and for your patience as we work through our software development phase. This is such a critical time — I hope our software app. will be ready soon, soon enough to keep the villages standing in Area C.
I am happy to tell you that work has resumed to finish our first three Rebuilding to Remain homes in Palestine.
Nearly 700 donors like you helped Rebuilding Alliance meet our Rebuilding to Remain fund raising goal, and we built the first 3 homes as promised in Al Aqaba Village in the Jordan Valley. This is one of the areas of the West Bank that is currently under demolition orders by the Israeli Army, Area C. We worked directly with the families to design energy efficient homes, together daring to draft Palestinian Building Permits where none existed, and created the first mortgage loan program for Area C.
Instead of waiting for the finishing grants promised by the Palestinian National Authority (its been over one year now), the families have agreed to extend their mortgage loan and Rebuilding Alliance is raising the funds caused by that shortfall to buy the doors, windows, tiles, and plumbing to finish so they can move in. Thanks to recent donations we are transferring $7000 this month in extended mortgage loans and will transfer additional loans each month as soon as donations arrive.
If only a small amount is raised each month, the families have decided to finish the homes one by one instead of finishing all simultaneously. They declined to draw straws to choose which home is finished first. Instead, Nabil, Safah, Othman and Sara all decided that Sadeq's house should be finished first because Sadeq's wedding waits for the day he can bring his bride home.
As you can see in the attached itemized budget, the total finishing costs for all three homes is $38,862. The families will be doing the painting, reducing the total to $33,417. With our transfer of $7000, we just need $26,417 to finish.
If we could finish all three at the same time it would be both safer and also, newsworthy as the village will hold a grand homecoming celebration that will be truly inspiring. All three homes could be finished in early March if all of us make a one-time donation of $50. Let's make this happen.
If you would like to join me for that Homecoming celebration (and maybe even Sadeq's wedding), please consider travelling with me on Rebuilding Alliance's first-ever study tour, February 24-March 6th. Please give me a call if you would like to discuss a major donation or would like more information about the study tour. My cellphone is 650 440 9667.
I look forward to your reply.


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Italian Stocks: Amplifon, Beni Stabili, Fiat, Pirelli, Tod's
April 15 (Bloomberg) -- Italy's benchmark FTSE MIB Index rose for a second day, gaining 58.82, or 0.3 percent, to 23,539.24 in Milan.
The following stocks were among the most active on the Italian market today.
Amplifon SpA (AMP IM) advanced 13.75 cents, or 3.5 percent, to 4.13 euros, a second day of gains. Equita Sim SpA increased its price estimate on the world's largest hearing-aid distributor to 4.4 euros from 4.2 euros and kept a "buy" rating, saying in a note that it expects first-quarter results to be "good in terms of sales and margins."
Beni Stabili SpA (BNS IM) rose 3.8 cents, or 5.7 percent, to 70.5 cents, ending a three-day loss. The real-estate company sold a stake of about 7 percent in the company for 66 euro cents a share.
Equita Sim SpA lifted its price estimate on the stock by 3 percent to 80 cents as the "company will definitely gain the REIT status."
D'Amico International Shipping SA (DIS IM) gained for a third session, increasing 1.2 cents, or 1 percent, to 1.25 euros. The oil-transport company signed a vessel deal with Exxon Mobil Corp.
Fiat SpA (F IM) rose 10 cents, or 1 percent, to 9.90 euros, extending gains of 2.4 percent yesterday. Sanford C. Bernstein & Co. increased its price projection on the Italian carmaker to 11 euros from 10 euros and kept a "market perform" recommendation. The brokerage said in a note that it believes "Fiat will soon announce that Chrysler Group LLC exited the first quarter with a profitable performance in March, an astonishing outcome given poor volumes and market share, rising fleet sales and still high incentives." The brokerage remains "cautious on its ultimate long-term prospects."
Pirelli & C. SpA (PC IM) gained for a third session, increasing 0.3 percent to 45.15 cents. Kepler Capital Markets reiterated a "buy" recommendation on the stock, saying in a note that the real-estate spinoff is "one of the pillars" behind its positive stance. Pirelli & C. Real Estate SpA (PRS IM) rose 1.5 percent to 49 cents after climbing 4.1 percent yesterday.
Savings shares of Telecom Italia SpA (TITR IM) rose 0.5 percent to 89.8 cents after having their price estimate lifted by 22 percent at ING Groep NV. The brokerage also increased its price estimate on the ordinary shares (TIT IM) by 9.5 percent. The common shares rose 0.4 percent to 1.13 euros.
Tod's SpA (TOD IM) gained 1.11 euros, or 2 percent, to 56.21 euros, ending a two-day decline. Societe Generale SA increased its price estimate on the Italian luxury-goods maker known for its rubber-studded driving shoes to 62 euros from 55 euros, saying in a note that the company "is now on track to catch up with peers and return to outperformance."
To contact the reporter on this story: Francesca Cinelli in Milan at email@example.com.
To contact the editor responsible for this story: David Merritt at firstname.lastname@example.com.


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HSBC "lift" by Grey London
Agency: Grey London
Rating: 5.0
By Matthew Chapman, marketingmagazine.co.uk, Monday, 30 January 2012 01:04PM
T-Mobile customers will be able to sign up to the uncapped package from 1 February for £41 a month.
The unlimited data package will also include tethering, which allows the phone to be used to provide a Wi-Fi connection for other computers and tablets.
It is believed T-Mobile hopes the proposition will position it as a good-value brand that can compete with O2 and Vodafone, while offering the prices of Three and Tesco Mobile.
Three currently offers unlimited data and tethering for £25 a month via its One Plan, but caps cross-network calls at 2,000 minutes.
The Orange campaign will also launch this week, but will not involve a new proposition.
A spokeswoman for the parent company Everything Everywhere said: "There's not actually a new proposition for the Orange campaign. It will be a proposition that we already have out there.
Speculation about the future of the T-Mobile and Orange brands was sparked once again earlier this month by a bond issue prospectus issued by Everything Everywhere, which said: "The development of an additional or new brand is an option under consideration, which may be complementary to or in substitution for one or both of the existing brands of T-Mobile and Orange."
Follow Matthew Chapman at @mattchapmanUK
This article was first published on marketingmagazine.co.uk
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Agency: Grey London
Rating: 5.0


text:
Michelle Obama: 'Busy single mother'
Sometimes, when you least expect it, parapraxis rears its ugly head : http://www.washingtonpost.com/blogs/post-politics/wp/2013/04/04/michelle-obama-accidentally-calls-herself-busy-single-mother
By: ConspiracyTardLL | Comments: 44 | Views: 939 | Votes: 2 | Shared: 0
Location: United States | Leaked: Apr-4-2013 in Politics
Michelle Obama Fitness Plan Starves Kids for Hours
Lisa Putnam is a fifth grade teacher in the Chicago Public School system. She and her students were very excited about participating in the Michelle Obama's Let's Move kickoff even in
By: Detroit Iron | Comments: 64 | Views: 2728 | Votes: 1 | Shared: 0
Location: Chicago, Illinois, United States | Leaked: Mar-10-2013 in Other News, Politics
Tuesday 2.26/2013 ABC's "Good Morning America" edited out an inaccurate assertion by First Lady Michelle Obama that the gunman in a Chicago killing used an "automatic weapon." Regarding the death of
By: grimghost | Comments: 53 | Views: 1902 | Votes: 6 | Shared: 27
Location: Washington, District of Columbia, United States | Leaked: Feb-28-2013 in Politics
Michelle Obama rolls eyes at John Boehner
NO audio of their exchange so, for now, it's impossible to know exactly what Boehner had said. In fact, it's entirely possible that Michelle Obama's eye roll was simply a reaction to an innocuous
By: kings World | Comments: 45 | Views: 1837 | Votes: 2 | Shared: 0
Location: Washington, District of Columbia, United States | Leaked: Jan-22-2013 in Politics
Michelle Obama has been nominated in AskMen's Top 99 Most Desirable Women
This is what my fellow Americans find attractive, folks: http://www.askmen.com/specials/2013_top_99/33-michelle-obama.html
By: kerensky204 | Comments: 187 | Views: 2103 | Votes: 1 | Shared: 20
Leaked: Dec-22-2012 in Other News
Michelle Obama And Girls Already In Hawaii, Separate Travel Costs Taxpayers $100K
The high price of impatience: Michelle jets off to Hawaii with the kids for 17 day vacation before the President can leave ... at a cost of $100,000 to the taxpayer The Obama family had planne
By: Bob_Lablaw | Comments: 52 | Views: 1510 | Votes: 4 | Shared: 49
Leaked: Dec-20-2012 in Other News, Politics, WTF
Michelle Obama and Elmo
Elmo helped Michelle Obama promote eating right, exercising regularly and being a positive role model for kids
By: Bob_Lablaw | Comments: 59 | Views: 1031 | Votes: 1 | Shared: 0
Leaked: Nov-12-2012 in WTF
Creston Classic Rodeo Announcer / Clown Mike Hayhurst Makes Racist Joke about Michelle Obama
. http://sharkonline.org Afro.com ------------------------------ "Playboy is offering Ann Romney $250,000 to pose in the magazine and the White House is upset about it because National Geographi
By: dingledd | Comments: 26 | Views: 1922 | Votes: 0 | Shared: 0
Location: California, United States | Leaked: Sep-28-2012 in Politics
Lawrence O'Donnell: Michelle Obama Is 'The Best Speechmaker in the History of the First Ladyship'
In the latest episode of Gush and Tingles, we find Larry enraptured with another man's wife.... http://newsbusters.org/blogs/noel-sheppard/2012/09/04/lawrence-odonnell-michelle-obama-best-speechmak
By: Yukon6400 | Comments: 71 | Views: 1145 | Votes: 0 | Shared: 0
Location: United States | Leaked: Sep-5-2012 in Politics
Media Praises Michelle Obama's $6,800 Shirt (After Bashing Ann Romney's $990 One)
TheBlaze does not usually report on fashion trends or presidential outfits, but in this case, a shirt forms part of a larger narrative. Over the weekend, Michelle Obama "wowed" at Buckingham Pala
By: aranger45 | Comments: 23 | Views: 4607 | Votes: 2 | Shared: 24
Location: New York, New York, United States | Leaked: Jul-30-2012 in WTF
Michelle Obama's $6,800 shirt is fine, Ann Romney's $900 one is "out of touch"
http://www.theblaze.com/stories/fit-for-a-queen-media-praises-michelle-obamas-6800-shirt-after-bashing-ann-romneys-990-one/ TheBlaze does not usually report on fashion trends or presidential outfits,
By: yorba | Comments: 117 | Views: 5165 | Votes: 7 | Shared: 64
Location: London, England, United Kingdom (UK/GB) | Leaked: Jul-30-2012 in Politics
Michelle Obama: "Change is slow"
Nice try, sister. Your hollow and inept campaign of cliches and cutesy one-liners are a national joke, sooooooooooooo spin that cliche into something else. Priceless. Michelle Obama seems to hav
By: yorba | Comments: 79 | Views: 1135 | Votes: 2 | Shared: 0
Location: Nevada, United States | Leaked: May-2-2012 in Politics
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HANNIBAL Set for April Premiere on NBC
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|Related: HANNIBAL, NBC
NBC's Hannibal has (finally) received a premiere date.
HANNIBAL, featuring one of the most fascinating literary characters: psychiatrist-turned-serial killer, will officially premiere on Thursday, April 4 at 10PM. The drama adaptation of of Thomas Harris' novels takes the time slot formerly held by the short-lived DO NO HARM.
Creator Bryan Fuller announced the news via Twitter today, posting: @BryanFuller: #Hannibal Requests the Honor of your Presence for Dinner Thursday April 4 10PM @NBC -- Saving you a place at the table.
The post also included a kitschy photo of its star, Mads Mikkelsen.
Will Graham is a gifted criminal profiler who is on the hunt for a serial killer with the FBI. Graham's unique way of thinking gives him the astonishing ability to empathize with anyone - even psychopaths. He seems to know what makes them tick. But when the mind of the twisted killer he's pursuing is too complicated for even Will to comprehend, he enlists the help of Dr. Lecter, one of the premier psychiatric minds in the country. Armed with the uncanny expertise of the brilliant doctor, Will and Hannibal (known as a serial killer only to the audience) form a brilliant partnership and it seems there's no villain they can't catch.
HANNIBAL is set to feature a slew of guest stars including Gillian Anderson, Eddie Izzard, Molly Shannon, Ellen Green, and Raul Esparza.
About Author
- CNBC to Air THE MAKING OF DIG, the USA Network Event Series, 3/1
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- Discovery Family to Premiere New Episodes of TRANSFORMERS RESCUE BOTS, Today
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Death Note V09 (2007)
Learn more about Death Note V09:
|Near gains another ally when Aizawa of the task force discovers Light's treachery. Light's own disciples are hard at work doing his bidding, though the ideal world Light is striving to create looks more and more like one ruled by fear alone. All the players converge in a single warehouse, where Near and Light play their final hands. The end is nigh...but whose?
Contains episodes 33-37 of Death Note!
"...smartly written and full of originality with two intriguing central characters. Paul Pritchard, DVD Verdict
Editor's NoteWhen student Light Yagami discovers a mysterious notebook, he inherits an unwelcome power: the ability to determine who will die. Can Light use his powers for good and to counteract evil?
Cast & Crew
|Alessandro Juliani - Voice
|Shannon Chan-Kent - Voice
|Madhouse - Animation Producer
|Brad Swaile - Voice
|Tetsuro Araki - Director
Customer Reviews of Death Note V09
Death Note9/18/2013
I've always loved Death Note, it's been one my top favorite anime shows for about 4 years now. And Death Note vol.9 contains the very last episodes ever. It can be pretty exciting and suspenseful on what's going to happen next, or what crazy turn it could take. But my opinion on the last episode is a little different, because it had a huge blood trail, and I've seen that too many times in anime shows. I wish they would have kept the ending like it was in the books, since it didn't leave that much of a blood trail. Instead, he just looked like a pathetic child in front of everyone. But other than that, I think the 9th volume is great, especially since it completes your Death Note series collection.


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Are you Donna O Butcher?Claim your profile
Publications (16)94.46 Total impact
Article: Abstract 1049: Quantitative immunofluorescence assessment of MET and epithelial to mesenchymal transition (EMT) biomarker modulation by antiangiogenic inhibitors in xenograft tumor tissuesProceedings of the American Association for Cancer Research 05/2014; DOI:10.1158/1538-7445.AM2014-1049
Article: Abstract 1500: Development of a Quantitative Immunofluorescence imaging assay to assess -catenin translocation and multiplex biomarkers for Epithelial-Mesenchymal Transition (EMT) in tumor tissues.Cancer Research 08/2013; 73(8 Supplement):1500-1500. DOI:10.1158/1538-7445.AM2013-1500 · 9.28 Impact Factor
Article: Abstract 1173: Development of calibrators and controls as quality control tools for clinical implementation of quantitative immunofluorescence assays for pharmacodynamic biomarkers of molecular targeted agents in tumor biopsies.Cancer Research 08/2013; 73(8 Supplement):1173-1173. DOI:10.1158/1538-7445.AM2013-1173 · 9.28 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Increased serum levels of IL-15 are reported in type 1 diabetes (T1D). Here we report elevated serum soluble IL-15Rα levels in human T1D. To investigate the role of IL-15/IL-15Rα in the pathogenesis of T1D, we generated double transgenic mice with pancreatic β-cell expression of IL-15 and IL-15Rα. The mice developed hyperglycemia, marked mononuclear cell infiltration, β-cell destruction, and anti-insulin autoantibodies that mimic early human T1D. The diabetes in this model was reversed by inhibiting IL-15 signaling with anti-IL2/IL15Rβ (anti-CD122), which blocks IL-15 transpresentation. Furthermore, the diabetes could be reversed by administration of the Janus kinase 2/3 inhibitor tofacitinib, which blocks IL-15 signaling. In an alternative diabetes model, nonobese diabetic mice, IL15/IL-15Rα expression was increased in islet cells in the prediabetic stage, and inhibition of IL-15 signaling with anti-CD122 at the prediabetic stage delayed diabetes development. In support of the view that these observations reflect the conditions in humans, we demonstrated pancreatic islet expression of both IL-15 and IL-15Rα in human T1D. Taken together our data suggest that disordered IL-15 and IL-15Rα may be involved in T1D pathogenesis and the IL-15/IL15Rα system and its signaling pathway may be rational therapeutic targets for early T1D.Proceedings of the National Academy of Sciences 07/2013; DOI:10.1073/pnas.1312911110 · 9.81 Impact Factor
Article: Abstract 4796: Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody.[Show abstract] [Hide abstract]
ABSTRACT: Reactive oxygen species generated by NADPH oxidase 5 (Nox5) have been implicated in physiological and pathophysiological signaling pathways, including cancer development and progression. However, because immunological tools are lacking, knowledge of the role of Nox5 in tumor biology has been limited; the expression of Nox5 protein across tumors and normal tissues is essentially unknown. Here, we report the characterization and use of a mouse monoclonal antibody against a recombinant Nox5 protein (600-746) for expression profiling of Nox5 in human tumors by tissue microarray analysis. Using our novel antibody, we also report the detection of endogenous Nox5 protein in human UACC-257 melanoma cells. Immunofluorescence, confocal microscopy, and immunohistochemical techniques were employed to demonstrate Nox5 localization throughout UACC-257 cells, with perinuclear enhancement. Tissue microarray analysis revealed, for the first time, substantial Nox5 overexpression in several human cancers including those of prostate, breast, colon, lung, brain, and ovary as well as in malignant melanoma and non-Hodgkin lymphoma; expression in most non-malignant tissues was negative to weak. This validated mouse monoclonal antibody will promote further exploration of the functional significance of Nox5 in human pathophysiology, including tumor cell growth and proliferation.Free Radical Biology and Medicine 07/2013; 65(8 Supplement). DOI:10.1016/j.freeradbiomed.2013.07.005 · 5.71 Impact Factor
Article: Activation of TLR4 Is Required for the Synergistic Induction of Dual Oxidase 2 and Dual Oxidase A2 by IFN-γ and Lipopolysaccharide in Human Pancreatic Cancer Cell Lines.[Show abstract] [Hide abstract]
ABSTRACT: Pancreatitis is associated with release of proinflammatory cytokines and reactive oxygen species and plays an important role in the development of pancreatic cancer. We recently demonstrated that dual oxidase (Duox)2, an NADPH oxidase essential for reactive oxygen species-related, gastrointestinal host defense, is regulated by IFN-γ-mediated Stat1 binding to the Duox2 promoter in pancreatic tumor lines. Because LPS enhances the development and invasiveness of pancreatic cancer in vivo following TLR4-related activation of NF-κB, we examined whether LPS, alone or combined with IFN-γ, regulated Duox2. We found that upregulation of TLR4 by IFN-γ in BxPC-3 and CFPAC-1 pancreatic cancer cells was augmented by LPS, resulting in activation of NF-κB, accumulation of NF-κB (p65) in the nucleus, and increased binding of p65 to the Duox2 promoter. TLR4 silencing with small interfering RNAs, as well as two independent NF-κB inhibitors, attenuated LPS- and IFN-γ-mediated Duox2 upregulation in BxPC-3 cells. Induction of Duox2 expression by IFN-γ and LPS may result from IFN-γ-related activation of Stat1 acting in concert with NF-κB-related upregulation of Duox2. Sustained extracellular accumulation of H(2)O(2) generated by exposure to both LPS and IFN-γ was responsible for an ∼50% decrease in BxPC-3 cell proliferation associated with a G(1) cell cycle block, apoptosis, and DNA damage. We also demonstrated upregulation of Duox expression in vivo in pancreatic cancer xenografts and in patients with chronic pancreatitis. These results suggest that inflammatory cytokines can interact to produce a Duox-dependent pro-oxidant milieu that could increase the pathologic potential of pancreatic inflammation and pancreatic cancer cells.The Journal of Immunology 01/2013; DOI:10.4049/jimmunol.1201725 · 5.36 Impact Factor
Article: Restricted Cell Surface Expression of Receptor Tyrosine Kinase ROR1 in Pediatric B-Lineage Acute Lymphoblastic Leukemia Suggests Targetability with Therapeutic Monoclonal Antibodies.[Show abstract] [Hide abstract]
ABSTRACT: Despite high cure rates for pediatric B-lineage acute lymphoblastic leukemia (B-ALL), short-term and long-term toxicities and chemoresistance are shortcomings of standard chemotherapy. Immunotherapy and chemoimmunotherapy based on monoclonal antibodies (mAbs) that target cell surface antigens with restricted expression in pediatric B-ALL may offer the potential to reduce toxicities and prevent or overcome chemoresistance. The receptor tyrosine kinase ROR1 has emerged as a candidate for mAb targeting in select B-cell malignancies. Using flow cytometry, Western blotting, immunohistochemistry, and confocal immunofluorescence microscopy, we analyzed the cell surface expression of ROR1 across major pediatric ALL subtypes represented by 14 cell lines and 56 primary blasts at diagnosis or relapse as well as in normal adult and pediatric tissues. Cell surface ROR1 expression was found in 45% of pediatric ALL patients, all of which were B-ALL, and was not limited to any particular genotype. All cell lines and primary blasts with E2A-PBX1 translocation and a portion of patients with other high risk genotypes, such as MLL rearrangement, expressed cell surface ROR1. Importantly, cell surface ROR1 expression was found in many of the pediatric B-ALL patients with multiply relapsed and refractory disease and normal karyotype or low risk cytogenetics, such as hyperdiploidy. Notably, cell surface ROR1 was virtually absent in normal adult and pediatric tissues. Collectively, this study suggests that ROR1 merits preclinical and clinical investigations as a novel target for mAb-based therapies in pediatric B-ALL. We propose cell surface expression of ROR1 detected by flow cytometry as primary inclusion criterion for pediatric B-ALL patients in future clinical trials of ROR1-targeted therapies.PLoS ONE 12/2012; 7(12):e52655. DOI:10.1371/journal.pone.0052655 · 3.53 Impact Factor
Article: A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers[Show abstract] [Hide abstract]
ABSTRACT: Over 50% of patients with colorectal cancer (CRC) will progress and/or develop metastases. Biomarkers capable of predicting progression, risk stratification and therapeutic benefit are needed. Cancer stem cells are thought to be responsible for tumor initiation, dissemination and treatment failure. Therefore, we hypothesized that CRC cancer stem cell markers (CRCSC) will identify a group of patients at high risk for progression. Paraffin-embedded tissue cores of normal (n=8), and histopathologically well-defined primary (n= 30) and metastatic (n=10) CRC were arrayed in duplicate on tissue microarrays (TMAs). Expression profiles of non-CD133 CRCSC (CD29, CD44, ALDH1A1, ALDH1B1, EpCam, and CD166) were detected by immunohistochemistry and the association with clinicopathological data and patient outcomes was determined using standard statistical methodology. An independent pathologist, blinded to the clinical data scored the samples. Scoring included percent positive cells (0 to 4, 0 = <10%, 1 = 10 - 24%, 2 = 25 - 49%, 3 = 50 - 74%, 4 = 75 - 100%), and the intensity of positively stained cells (0 to 4; 0 = no staining, 1 = diminutive intensity, 2 = low intensity, 3 = intermediate intensity, 4 = high intensity). The pathologic score represents the sum of these two values, reported in this paper as a combined IHC staining score (CSS). Of 30 patients 7 were AJCC stage IIA, 10 stage IIIB, 7 stage IIIC and 6 stage IV. Median follow-up was 113 months. DFI was 17 months. Median overall survival (OS) was not reached. Stage-specific OS was: II - not reached; III - not reached; IV - 11 months. In a univariate analysis, poor OS was associated with loss of CD29 expression; median OS, 32 months vs. not reached for CSS 3-7 vs. >7.5, respectively; p=0.052 comparing entire curves, after adjustment. In a Cox model analysis, loss of CD29 exhibited a trend toward association with survival (p=0.098) after adjusting for the effect of stage (p=0.0076). Greater expression of ALDH1A1 was associated with increasing stage (p=0.042 over stages 2, 3b, 3c, and 4) while loss of CD29 expression exhibited a trend toward being associated with stages 3 and 4 (p=0.08). Compared to normal colon tissue, primary tumors were associated with increased expression of ALDH1B1 (p=0.008). ALD1H1B1 expression level differed according to whether the tumor was moderately or poorly differentiated, well differentiated, or mucinous; the highest expression levels were associated with moderately or poorly differentiated tumors (p=0.011). Lymph node metastases were associated with a trend toward decreased expression of EpCAM (p = 0.06) when comparing 0 vs. 1 vs. 2+ positive lymph nodes, as was CD29 (p = 0.08) when comparing 0 vs. any positive lymph nodes. Compared to normal colon tissue metastatic colon cancers from different patients were associated with increased ALDH1B1 expression (p=0.001) whereas CD29 expression was higher in normal colonic tissue (p=0.014). CD29 may be associated with survival as well as clinical stage and number of lymph nodes. ALDH1B1 expression was associated with differentiation as well as type of tissue evaluated. ALDH1A1 was associated with clinical stage, and decreased EpCAM expression was found in patients with advanced lymph node stage. CRCSCs may be useful biomarkers to risk stratify, and estimate outcomes in CRC. Larger prospective studies are required to validate the current findings.Journal of Cancer 06/2012; 3:231-40. DOI:10.7150/jca.4542 · 2.64 Impact Factor
Article: Abstract 1621: The proprotein convertase PCSK1 is a novel drug target in alveolar soft part sarcoma (ASPS)Cancer Research 07/2011; 71(8 Supplement):1621-1621. DOI:10.1158/1538-7445.AM2011-1621 · 9.28 Impact Factor
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ABSTRACT: In vitro growth of alveolar soft part sarcoma (ASPS) and establishment of an ASPS cell line, ASPS-1, are described in this study. Using a recently developed xenograft model of ASPS derived from a lymph node metastasis, organoid nests consisting of 15 to 25 ASPS cells were isolated from ASPS xenograft tumors by capture on 70 μm filters and plated in vitro. After attachment to the substratum, these nests deposited small aggregates of ASPS cells. These cells grew slowly and were expanded over a period of 3 years and have maintained characteristics consistent with those of both the original ASPS tumor from the patient and the xenograft tumor including (1) presence of the alveolar soft part locus-transcription factor E3 type 1 fusion transcript and nuclear expression of the alveolar soft part locus-transcription factor E3 type 1 fusion protein; (2) maintenance of the t(X;17)(p11;q25) translocation characteristic of ASPS; and (3) expression of upregulated ASPS transcripts involved in angiogenesis (ANGPTL2, HIF-1-α, MDK, c-MET, VEGF, and TIMP-2), cell proliferation (PRL, PCSK1), metastasis (ADAM9), as well as the transcription factor BHLHB3 and the muscle-specific transcripts TRIM63 and ITGβ1BP3. This ASPS cell line forms colonies in soft agar and retains the ability to produce highly vascularized ASPS tumors in NOD.SCID/NCr mice. Immunohistochemistry of selected ASPS markers on these tumors indicated similarity to those of the original patient tumor as well as to the xenografted ASPS tumor. We anticipate that this ASPS cell line will accelerate investigations into the biology of ASPS including identification of new therapeutic approaches for treatment of this slow growing soft tissue sarcoma.Journal of Pediatric Hematology/Oncology 07/2011; 33(5):360-8. DOI:10.1097/MPH.0b013e3182002f9f · 0.96 Impact Factor
Article: Abstract 3415: Therapeutic targeting of the ASPL-TFE3 gene fusion in ASPS-1, a novel cell line derived from metastatic alveolar soft part sarcoma (ASPS)Cancer Research 01/2011; 70(8 Supplement):3415-3415. DOI:10.1158/1538-7445.AM10-3415 · 9.28 Impact Factor
Article: M1221 The Role of Substance P and Mast Cells as Immunohistologic Biomarkers for Chronic Abdominal Pain in ChildrenGastroenterology 05/2010; 138(5). DOI:10.1016/S0016-5085(10)61647-2 · 13.93 Impact Factor
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ABSTRACT: Cancer cells undergo significant changes in carbohydrate expression, and these alterations can be useful as biomarkers and therapeutic targets. In this study, we investigated the expression of carbohydrate antigens containing a terminal GalNAcalpha1-3Gal or GalNAcalpha1-6Gal on human cervix and cervical carcinoma. Monoclonal antibodies to each of these carbohydrates were generated by immunizing rabbits with the corresponding antigen conjugated to KLH followed by hybridoma production. Antibodies were screened and evaluated using a combination of carbohydrate microarray profiling, ELISA, dot blot and immunohistochemical staining to verify specificity. Antibody 132-3 was found to selectively recognize GalNAcalpha1-3Gal with little cross-reactivity to other structurally similar antigens such as GalNAcalpha1-6Gal, blood group A, Forssman antigen and the Tn antigen on both solution assays and human tissue. Although GalNAcalpha1-6Gal expression was not detected, GalNAcalpha1-3Gal expression was found on 55% of squamous cell carcinomas. Expression in normal tissue was observed but was restricted to the suprabasal epithelial layer. Importantly, we found expression of the antigen on cervical cancer had a statistically significant correlation with the 5-year survival rate of the patients (48 vs. 85% for antigen negative vs. positive, p = 0.017). Expression of GalNAcalpha1-3Gal did not correlate with other clinical factors including tumor stage, size and lymph node metastasis, indicating the antigen is a new, independent biomarker for the prognosis of cervical cancer.International Journal of Cancer 01/2010; 126(2):459-68. DOI:10.1002/ijc.24716 · 5.01 Impact Factor
Article: Therapeutic vulnerability of an in vivo model of alveolar soft part sarcoma (ASPS) to antiangiogenic therapy.[Show abstract] [Hide abstract]
ABSTRACT: In vivo growth of alveolar soft part sarcoma (ASPS) was achieved using subcutaneous xenografts in sex-matched nonobese diabetic severe combined immunodeficiency mice. One tumor, currently at passage 6, has been maintained in vivo for 32 months and has maintained characteristics consistent with those of the original ASPS tumor including (1) tumor histology and staining with periodic acid Schiff/diastase, (2) the presence of the ASPL-TFE3 type 1 fusion transcript, (3) nuclear staining with antibodies to the ASPL-TFE3 type 1 fusion protein, (4) maintenance of the t(X;17)(p11;q25) translocation characteristic of ASPS, (5) stable expression of signature ASPS gene transcripts and finally, the development and maintenance of a functional vascular network, a hallmark of ASPS. The ASPS xenograft tumor vasculature encompassing nests of ASPS cells is highly reactive to antibodies against the endothelial antigen CD34 and is readily accessible to intravenously administered fluorescein isothiocyanate-dextran. The therapeutic vulnerability of this tumor model to antiangiogenic therapy, targeting vascular endothelial growth factor and hypoxia-inducible factor-1 alpha, was examined using bevacizumab and topotecan alone and in combination. Together, the 2 drugs produced a 70% growth delay accompanied by a 0.7 net log cell kill that was superior to the antitumor effect produced by either drug alone. In summary, this study describes a preclinical in vivo model for ASPS which will facilitate investigation into the biology of this slow growing soft tissue sarcoma and demonstrates the feasibility of using an antiangiogenic approach in the treatment of ASPS.Journal of Pediatric Hematology/Oncology 09/2009; 31(8):561-70. DOI:10.1097/MPH.0b013e3181a6e043 · 0.96 Impact Factor
Article: Resolving conflicting data on expression of the Tn antigen and implications for clinical trials with cancer vaccines.[Show abstract] [Hide abstract]
ABSTRACT: The tumor-associated Tn antigen has been investigated extensively as a biomarker and therapeutic target. Cancer vaccines containing the Tn antigen as a single tumor antigen or as a component of a polyvalent vaccine have progressed into phase I and II clinical trials. One major focus of Tn-based vaccines is the treatment of prostate cancer patients. Although expression of the antigen on prostate tumors is a critical prerequisite, previous reports investigating Tn expression in prostate tumors have produced conflicting results. Using a combination of immunohistochemistry and carbohydrate microarray profiling, we show that only 4% to 26% of prostate tumors express the Tn antigen. Based on our results, the majority of prostate cancer patients do not express the appropriate antigen. Therefore, efforts to preselect the subset of prostate cancer patients with Tn-positive tumors or apply Tn vaccines to other cancers with higher rates of antigen expression could significantly improve clinical response rates. Because conflicting information on carbohydrate expression is a general problem for the field, the approach described in this article of analyzing antigen expression with multiple antibodies and using carbohydrate microarray profiles to interpret the results will be useful for the development of other carbohydrate-based cancer vaccines and diagnostics.Molecular Cancer Therapeutics 05/2009; 8(4):971-9. DOI:10.1158/1535-7163.MCT-08-0934 · 6.11 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Alveolar soft-part sarcoma (ASPS) is an extremely rare, highly vascular soft tissue sarcoma affecting predominantly adolescents and young adults. In an attempt to gain insight into the pathobiology of this enigmatic tumor, we performed the first genome-wide gene expression profiling study. For seven patients with confirmed primary or metastatic ASPS, RNA samples were isolated immediately following surgery, reverse transcribed to cDNA and each sample hybridized to duplicate high-density human U133 plus 2.0 microarrays. Array data was then analyzed relative to arrays hybridized to universal RNA to generate an unbiased transcriptome. Subsequent gene ontology analysis was used to identify transcripts with therapeutic or diagnostic potential. A subset of the most interesting genes was then validated using quantitative RT-PCR and immunohistochemistry. Analysis of patient array data versus universal RNA identified elevated expression of transcripts related to angiogenesis (ANGPTL2, HIF-1 alpha, MDK, c-MET, VEGF, TIMP-2), cell proliferation (PRL, IGFBP1, NTSR2, PCSK1), metastasis (ADAM9, ECM1, POSTN) and steroid biosynthesis (CYP17A1 and STS). A number of muscle-restricted transcripts (ITGB1BP3/MIBP, MYF5, MYF6 and TRIM63) were also identified, strengthening the case for a muscle cell progenitor as the origin of disease. Transcript differentials were validated using real-time PCR and subsequent immunohistochemical analysis confirmed protein expression for several of the most interesting changes (MDK, c-MET, VEGF, POSTN, CYP17A1, ITGB1BP3/MIBP and TRIM63). Results from this first comprehensive study of ASPS gene expression identifies several targets involved in angiogenesis, metastasis and myogenic differentiation. These efforts represent the first step towards defining the cellular origin, pathogenesis and effective treatment strategies for this atypical malignancy.BMC Cancer 02/2009; 9(1):22. DOI:10.1186/1471-2407-9-22 · 3.32 Impact Factor
Top Journals
National Cancer Institute (USA)Maryland, United States
National Institutes of Health
베서스다, Maryland, United States
- Laboratory of Pathology
Leidos Biomedical ResearchФредерик, Maryland, United States
NCI-FrederickФредерик, Maryland, United States
SAICMaryland, United States


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Lemon Basil Tuna Pockets
31 Jul 2010
|Canned 60% less salt tuna in spring water
|12 1⁄4 Ounce, drained (2 Cans, 6 1/8 Ounce Each)
|Chopped celery
|1⁄2 Cup (8 tbs)
|Sliced green onion
|1⁄4 Cup (4 tbs)
|Chopped fresh basil
|2 Tablespoon
|Oil free italian dressing
|2 Tablespoon (Commercial)
|Lemon juice
|2 Tablespoon
|1 Tablespoon
|Salt free lemon pepper seasoning
|1⁄4 Teaspoon
|1 Clove (5 gm), minced
|Lettuce leaves
|6 (Green Leaf)
|Tomato slices
|6 (1/4 Inch Thick)
|Whole wheat pita bread
|3 , cut in half crosswise (6 Inch Rounds)
Combine first 3 ingredients in a bowl; stir well.
Combine basil and next 5 ingredients; stir well.
Pour over tuna mixture; stir well.
Cover and refrigerate at least 1 hour.
Just before serving, place 1 lettuce leaf and 1 tomato slice in each pita half; spoon tuna mixture into pitas.
Recipe Summary
Difficulty Level:Easy
Course:Side Dish
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Lemon Basil Tuna Pockets Recipe


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ASUS GeForce GTX 980 Ti STRIX Review
Samsung 850 EVO 2TB SSD review
Zotac GeForce GTX 980 Ti AMP! Extreme Review
PowerColor Radeon R9 390 PCS+ 8GB review
MSI GeForce GTX 980 Ti Gaming OC Review
Guru3D Rig of the Month - June 2015
AMD Radeon R9 Fury X review
Corsair RM750i power supply review
MSI Radeon R9 390X Gaming 8G OC review
ASUS Radeon R9 380 STRIX review
Guru3D.com » News » Sennheiser
Sennheiser shows platform agnostic U 320 gaming headset
By Hilbert Hagedoorn on: 10/06/2012 06:48 AM | 2 comment(s) ]
A special headset is recently launched for the gaming consoles. Sennheiser has recently introduced Platform Agnostic U 320 Gaming Headset. You might have experienced wearing a headset that fails to cancel the surrounding sounds. You cannot concentrate on your games and get disturbed to some extent by the noise from outside. But this will not happen with U 320 Gaming Headset; it has noise cancellation technology. Sennheiser has launched the U 320, the firm's first multi-platform gaming headset which is compatible with Xbox 360, PS3, PC and Mac.Read more
Tagged as: Sennheiser, agnostic, gaming, headset, platform
Guru3D.com » News » Sennheiser


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Cappadocia[kap′ə dō′s̸hē ə, -s̸hə]
ancient kingdom, later a Roman province, in E Asia Minor: fl. 3d cent. -1st cent.
An ancient region of Asia Minor in present-day east-central Turkey. Heart of a Hittite state and later a Persian satrapy, it was annexed by the Romans in AD 17.
Related Forms:
- Cap′pa·do′cian
& n.
Proper noun
- An ancient region in the center of Asia Minor, in present-day Turkey
From Ancient Greek Καππαδοκία (Kappadokia), from Old Persian (katpatuka).


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Antibiotics given to infant mice may have long-term effects on the animals' metabolism and gut microbiota.
Speaking of Vision Science
October 1, 2014|
October 2014's selection of notable quotes
October 1, 2014|
October 2014's selection of notable quotes
September 25, 2014|
Documenting the epigenetic landscape of human innate immune cells reveals pathways essential for training macrophages.
September 1, 2014|
Vein patterns in the wings of developing fruit flies never vary by more than the width of a single cell.
August 13, 2014|
Hemocytes can form neurons in adult crayfish, a study shows.
July 31, 2014|
Some genetic abnormalities that appear to have sprung up independently in children are in fact present in a portion of their parents' cells.
July 3, 2014|
The National Institutes of Health is funding six extramural medical centers to help identify the causes of mysterious diseases.
July 3, 2014|
Adult sickle-cell patients have safely stopped taking their immunosuppressant medication thanks to a new type of blood stem-cell transplant.
June 23, 2014|
Starvation suspends cellular activity in C. elegans larvae and extends their lifespan.
June 22, 2014|
ASC specks—protein aggregations that drive inflammation—are released from dying immune cells, expanding the reach of a defense response.
June 9, 2014|
Humans and coral share a cell-death pathway that has been conserved between them for more than half a billion years.


text: Hives from Bee Thinking have made long journeys to beekeepers in Canada, Australia, the United Kingdom, and beyond. They appear on the roofs of hotels, at schools, and increasingly at wineries and vineyards. With the heat of summer settling in around Bee Thinking Headquarters here in Portland, I decided to escape the city and head west into the Dundee Hills American Viticultural Area, a lush landscape of rolling vine-clad hills, distant forest ridges, and picturesque tasting rooms. Along the way I visited some well-known wineries that also keep bees in Bee Thinking hives. Sokol Blosser Winery began over 40 years ago and has developed a reputation for world-class Pinot Noir, among other varieties that they produce. The property stretches... Continue Reading →


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The anniversary event itself wasn't really what cured my ills. The extra things involved in the event were just little fun add-ons to the game. The main tasks in the game were still there for me: run Serpent Lantern, run NemCon, maybe level an alt, mess around on PTS, and roleplay. Even the "big bang" Destroid attacks were only a decent diversion for a half hour or so.
What really got my excitement going was the increased socialization. A lot of people claimed "the zones are empty," but that couldn't be further from the truth. I logged out one night in Millenium City #7 and logged in the next afternoon to Millenium City #20, with most of the lower instances completely full. That's close to 2000 players in just MC alone. I participated in a lot of roleplaying and hung out with the CORP guys during their RP event. I added over 10 people to my friends list last week.
The main reason my burnout was cured? I gained an optimistic look at where the game is headed.
To be honest, I already sort of mentioned this. You readers have already seen my thoughts on CO's future potential. I've always been a critical sort of person, so I am bound to bring up any flaws in a game that I play. However, in the case of CO, when I first started writing Behind the Mask, CO was just starting its upturn, and there were a lot of bad things to talk about. Now that I've spent a lot of time with the community and heard its collective thoughts, I realize that CO has started to fulfill some of that potential we knew it had when it first was announced.
Our story begins
Instead of writing something cool like a guide on how summoning rituals are awesome (next week, guys), I'm actually just going to recant my fun times during the anniversary event. I began the event playing my current main (it kind of changes frequently), since I was interested in participating in the CORP anniversary bash. I was level 38, in a very strange healer/tank build with sorcery powers, pets, Celestial heals and Defiance.
Anyway, I signed up for the PvP event and decided my gear was awful. A friend and I did some daily Serpent Lantern runs, and with the nice Anniversary experience boosters and resource boosters, I gained XP pretty quickly and banked a lot of cash to buy some really nice gear from the auction house. We did the runs on Elite difficulty, and I was kind of surprised by the difficulty. Our first few runs were actually sort of hard. As my gear got better and our strategies were refined, it obviously became clockwork, but the early runs especially were pretty challenging.
I'm going to pause for a minute to express some joy here. I do think that the Serpent Lantern rewards are too good, but I can't stress how awesome it is that they are bind-on-equip. I wish that the level 40 purple drops from various other dungeons were also bind on equip. The market actually serves a purpose now, with the Vibora costume pieces and SL equipment drops. This was my first real time using the market for anything useful, and I was so pleasantly surprised by the outcome that I had to mention it here.
I was pretty invigorated by playing SL with just a friend, to my surprise, so I didn't just log out after my daily runs. I would go off and level or roleplay, and I made some new friends pretty quickly. The number of RPers during the anniversary event had surged wildly, and Club Caprice was often full. Pretty soon, even when I was leveling, I would be buried in tells, talking about IC situations or OOC builds.
CORP's costume contest
The first day of the "Qularr Suck Anniversary Bash" was on Saturday, and it featured a number of themed costume contests. I'll be honest, here; I don't really hang out with the CORP guys even though I think what they do for the RP community is great. Thus, I was sort of an outsider, wall-flowering my way through the various contests. No one even laughed at my "shut down all the beacons" joke. Everyone else had a lot of fun. There was a ton of banter and people getting excited, plus water balloon fights and anniversary disco balls getting thrown every few minutes. I didn't win any of the costume contests, but I wasn't really all that surprised. I was just there to hang out and take screenshots, anyway.
Afterwards, a bunch of people started randomly dueling each other. When The Blue Bruiser (pic right; he got a runner-up prize for being in the "hottest girl" contest in that awful dress) started rolling faces left and right, I decided to step in and try my luck. It went pretty well.
For those readers who don't play CO, melee characters are generally seen as the new PvP FotM. I don't really agree that melee is the undisputed best in the game, and I like that it is slightly better than ranged overall. I think there are numerous counters and answers to melee that people haven't really explored, especially in duels. I would be lying if I said I didn't deliberately PvP on the wackiest build possible just to say that "yes, there are answers to melee you haven't thought of."
I won some battles and lost some, but my success with a build that did not use Ego Blade Breach, Defile, or traditional melee probably turned a few heads. I didn't make any friends at the event, though.
Afterwards, I roleplayed in CC and made a few more friends, some of whom had been at the costume contest. Again, there were tons of roleplayers packed in the club, and it was really entertaining just listening to people chat.
Qularr Suck Tournament
After a bit of a rough start with the organization, the tournament got under way, and a lot of the early rounds were kind of surprising. I don't mean surprising in that strange people won, but more surprising in that the people who lost put up really good fights. It was a little strange not seeing brutal one-sided battles happen every match, but there were a few. There was one near-disqualification for breaking the rules (he ended up just losing one round) but other than that, everything went pretty smoothly.
I chatted with some of the stronger competitors after the event, and we were in agreement that the huge number of martial artists and super-strength heroes was a little on the boring side for spectators. Playing in the event was fun, but watching the same Uppercut-Haymaker combos was not as enjoyable as watching the ranged characters bounce around with fire blasts, lightning blasts, and other cool explosive powers.
In the end, my wacky build took second place. I won in the semi-finals due to a time expiration, and the judges ruled that my opponent could not have broken my defense after a brutally intense match. In reality, I was playing with 110% of my mental energy focused on not throwing away the match, and one mistake would have lost it for me (he was a really powerful dual blades build). I lost in the finals to a Might heroine, but she stomped me pretty badly. I couldn't have reasonably defeated her without replacing some of my less-useful powers.
After the tournament, I got some cool 2nd place prizes, added some people to my friends list, and generally left with a lot of rep for being either cool, strange, a jerk, or a good PvPer. I'm not sure.
I want to contrast a bit the general perception of PvP with this event. PvP is generally seen as a gigantic e-peen booster. I hate the big egos involved in PvP, and after the kind of chilly reception I had at the costume event (mostly my fault for not being outgoing enough) I was sort of surprised to see how exciting and fun it could be to play in a PvP event. The real difference was the spectators, the competitors all being interested in the matches, and the overall expectation to not act like a jerk. Everyone was courteous when he or she lost (I think there may have been one exception but I don't recall), and everyone was really supportive of both the winners and the losers.
If PvP events were like that in general, I think more people would find them fun. Obviously not everyone will, but I think the biggest opposition to PvP is the ego in general.
After the event, I roleplayed more and added more people to my friends list. Eventually, the big Destroid attack came on the last day of the event. A huge number of Mega-Destroids accompanied by numerous standard Destroids attacked the city, and the zones flooded. Thousands of heroes arrived in Millenium City to battle the threat. However, for me it was just another string of cosmic boss fights. I got bored of fighting them pretty quickly and went back to roleplaying.
I actually stayed online, chatting, until the maintenance for the event began. I'd padded my friends list by a huge number and met a whole slew of other acquaintances.
The day after, I was surprised. Still hundreds and hundreds of people populated the game, and Club Caprice was so full I had a hard time getting in. Numerous people on my friends list had commented that they were here to stay, and I felt like we were going to keep some of this big surge of players. For me, the anniversary event may not have been that important mechanically, but socially it was a big hit. I think that the anniversary event breathed new life into CO in a different way -- it brought players in to try this "horrible" game that had received a lot of awful press.
And a lot of players found a new home.
Special thanks to @Reldin and all the people at CORP who put the effort into the player events.


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Pretty Little Liars
Pretty Little Liars Season 5 Midseason Finale Spoilers — Everything We Know So Far
It's hard to believe we only have one episode left of the Pretty Little Liars summer season. (Say it isn't so!) But the summer finale airs next Tuesday, and — as one of PLL's epic mid-season enders — it's sure to leave us reeling. Get a head start on your OMG moments with this spoiler guide. Here's everything we know about Season 5, Episode 12 ("Taking This One to the Grave").
Someone will die. The summer finale promises that someone will die, and it look like that person will meet a bloody end. The promo for the ep shows Holbrook presiding over a crime scene, saying: "The amount of blood in the house would indicate that the victim's wounds were fatal. We have ruled this a homicide." Hanna looks particularly upset about it. Is the victim someone she's close with?
Someone will get arrested. In the promo, we see Holbrook bursting into The Brew to arrest someone — and the Liars seem pretty upset about it. Is it one of their own? Is the Rosewood P.D. finally coming to some conclusions on all of the murder cases?
Someone thinks Alison is "A". Well, a lot of people probably think this, but — in the promo — Aria asks someone (Mona?) in seeming disbelief, "You think Alison is 'A'?!" Um, yeah. Where have you been Aria? Emily and Hanna both floated this theory last episode.
Emily v. Alison. We know that Em has already declared her defection from Team Ali, but it seems like she's putting her money where her mouth is in the finale. In the promo, we see her and Ali in a mini-confrontation. But it's not all hostility. In the Canadian promo, we see Emily trying to reason with Ali: "I don't want things to be like this," she tells Ali, who gives a devilish smile that only the camera can see.
Mona's Army assembles. In the Canadian promo, we see Mona on the phone telling someone: "Send out a code 'A'. She's plotting something big." We assume Mona is mobilizing her army against Ali, but will it be enough? According to Paige in the promo, "Ali is building an army of her own."
Spencer is an accessory. Spencer's borrowing a page from Aria's Book O' Accidentally Murdering and understandably freaking out about her part in Bethany Young's death. "In Melissa's story, I'm an accessory to murder," she says in the Canadian promo.
Officer Toby! Either Toby is taking a side job as a male stripper (yes, please) or he's already part of the Rosewood P.D. In the Canadian promo, we see him in full uniform, teasing Spencer: "Are you looking for trouble?"
Hanna's lying. Just when we thought things were good between Haleb! In the Canadian promo, Caleb calls Hanna out on lying to him. What is it this time? Is Hanna keeping mum about the new information in Bethany Young's murder? There are so many secrets to choose from.
Ezria embrace. After a half-season of angst, Ezria seems to be back on track. In the Canadian promo, we see Ezra hugging Aria. This looks like it comes outside of the murder scene. In a promo photo for the episode, we see Ezria baking together. Oy vey!
An unlikely ally. According to the synopsis, with the Liars "feeling trapped" by Ali and "A", they "turn to an unlikely person for help." Our money is on Mona. Not only has she been forging connections with the Liars in recent episodes, but she and Spencer seem to be on some kind of mission in these promo photos. Both girls are wearing nurse outfits and seem to be skulking through the halls of a hospital. Love it!
Holiday time. In this promo photo, we see Hanna and Emily hanging out amidst boxes of holiday decorations. Is it Christmas time in Rosewood or is Emily doing some spring cleaning? Given that we're getting a Christmas special and the other promo photos, we think it might be the former. Does this mean the Christmas episode will pick up directly following the summer finale?
Aria's getting messy. In another promo photo, Aria is looking guilty about some red liquid she's dropped on the floor. Given the nurse — possibly Mona or Spencer? — hanging out in the foreground, we're guessing this comes in the same mission that has the Liars breaking into a hospital — or Radley?
Paily reconciliation? This promo photo of Paige standing on a balcony next to a snowman is just screaming romantic resolution for Paily. Maybe we're projecting our own hopes and dreams for the characters here, but we're thinking Say Anything, we're thinking Romeo and Juliet, we're thinking every romantic film that involves some kind of heartfelt speech to someone standing on a balcony. Who's joining Team Optimism?
Catch the Pretty Little Liars Season 5 summer finale on Tuesday, August 26, 2014 at 8 p.m. ET/PT on ABC Family.


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So, did he or didn't he?
Tom Barrett said during Friday's gubernatorial debate that he believed Gov. Scott Walker had signed recall petitions against Wisconsin Sens. Herb Kohl and Russ Feingold.
Barrett's point was that Walker now decries recalls sparked by policy decisions, but that in 1997 Walker, then a state lawmaker, backed the ouster of the two Democrats for voting against a ban on certain partial-birth abortions.
How does Barrett know Walker signed the petitions?
He doesn't for sure, but he has heard that, says Phil Walzak, a Barrett campaign spokesman.
"He didn't offer it as an attack or assertion, just as a discussion point," Walzak said, noting that Barrett couched his statement by saying it was his "understanding."
Here's what Barrett said during the debate: "He has signed recall petitions, it's my understanding, against Senator Feingold, against Senator Kohl, not for criminal misbehavior, but because he disagreed with political decisions that were made."
Back to Walker. Did he sign?
The Journal Sentinel asked his campaign that about two weeks ago and got no answer. When asked again Saturday, Walker's campaign issued an email response:
"Once again, Mayor Barrett has made an accusation of which he has provided no back up or evidence," spokeswoman Ciara Matthews said. "The onus of this claim falls on Tom Barrett."
Who else would know? Maybe the organizers of the recall, which was a grass-roots effort with no party support, according to Carl Schroeder, who served as treasurer for First Breath Alliance, the 1997 recall group. The group never turned in the petitions, but said it collected all but 40,000 signatures of the 391,000 needed.
Schroeder said Saturday that he is unaware of Walker having signed the petitions.
He's not 100% sure Walker did not, but said he would be surprised to find out Walker did, because the group would have made a big deal out of it at the time. Schroeder was in charge of the petitions and read them closely.
Mark Neumann, a Republican congressman preparing in 1997 to run against Feingold for U.S. Senate, was the only public official who publicly supported the effort, to the group's knowledge, Schroeder said.
Schroeder said the recall drive was started by several anti-abortion Wisconsinites including himself, and was never embraced by the state Republican Party.
Why would Walker be reluctant to answer whether he signed?
It's possible he doesn't remember. Saying that he signed undercuts the GOP argument that only criminal malfeasance should spur a recall. He and others say the recall statute needs to be changed. Saying he didn't sign could make Walker, who is staunchly against abortion, look like he did not support the cause.
Of course, the petitions themselves would reveal whether Walker signed.
They were destroyed years ago, Schroeder said.


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Vanilla Chocolate Bombe
|For vanilla ice cream
|Vanilla ice cream
|1 Pint
|Egg yolks
|Single cream
|1 Pint (600 Milliliter)
|Vanilla pod
|Double cream
|1⁄2 Pint (300 Milliliter)
|For mousse
|Dark chocolate
|6 Ounce (185 Gram)
|Strong black coffee
|3 Tablespoon
|4 , separated
|1⁄2 Ounce, softened
|1 Tablespoon
|Caster sugar
|3 Tablespoon
|Double cream
|1⁄4 Pint, whipped (150 Milliliter)
1 For the ice cream in a bowl, place the sugar and egg yolks and whisk until thick and creamy.
2 In a heavy based saucepan, put single cream and the vanilla pod and simmer for 3 minutes.
3 Cool slightly, then remove the vanilla pod.
4 Gradually add half of the warm cream mixture to the egg mixture, beating well.
5 Add the egg mixture to the remaining cream.
6 Stir over a low heat until the mixture thickens and coats the back of a spoon.
7 Do not boil.
8 Set aside to cool.
9 Stir in the double cream and pour into a freezer-proof bowl lined with cling film.
10 Freeze until almost set.
11 Remove from the freezer, break up with a fork and put into a food processor.
12 Process until thick and creamy.
13 Pour into a 3 pt (1.8 ltr) bowl lined with cling film.
14 Cover a 1 pt (600 ml) bowl with cling film and press down into the mixture, forcing the ice cream up around the sides.
15 Freeze until firm.
16 For the chocolate mousse,in a bowl break the chocolate into small pieces and place it and the coffee.
17 Melt over a saucepan of simmering water, stirring until smooth.
18 Remove from the heat, beat in egg yolks one at a time.
19 Continue beating, add butter and brandy, allow the mixture to cool.
20 Beat the egg whites until soft peaks form, then beat in the sugar.
21 Fold egg whites and cream into the chocolate mixture.
22 Remove smaller mould from the ice cream.
23 Spoon the mousse into the centre of the ice cream and return to the freezer to set.
24 Serve chilled


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Details and Shopping
Customer Favorite
Mini wedge open-toe sandal with adjustable crisscross ankle straps. Wooden heel with polished natural finish.
*By Bronx
*By Bronx
Measurements:Wedge: 2 1/2 in = 6 1/3 cm
Rated 4.3 out of 5Â by 4 reviewers.
Rated 3 out of 5Â by halo_gal13 wood not as lovely Pretty and declicate BUT the wood heel is much duller, and has a less flattering colour/ pattern. Makes the one in the photo look 'oiled' by comparison 6.5.2014
Rated 5 out of 5Â by punkrocker cute! Very cute, got the size 9 in black and neutral colors. LOVE! 10.17.2014
Rated 4 out of 5Â by the_neen A Good Basic Great for work or going out. very comfortable height. Got the Tan color and its a great shade that works with almost anything i wear. It said in the description that the brand was "The Bronx" but once i received, the brand was called "Diba" which ive never heard of before, Not quite sure why that wasnt noted in the description. Regardless they're a good purchase especially at Sale price! 8.28.2014
Rated 5 out of 5Â by Alex82392 So cute! Bought these b/c my boyfriend is the same height as me and I don't like to be too much taller than him, these do the trick! I got the black and they're dainty and lovely. 7.18.2014
1-4 of 4
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Rehan Qr Photographer
RosieDemiseModel Female Shepperton, England, United Kingdom My MM URL: http://www.modelmayhem.com/rosiedemise
Mayhem # 3322107
About MeHi there first of all thank you for taking the time to read my portfolio.
I've always had a desire to model from watching modelling shows as a child to looking at photographers pictures on social media websites, and always thought i wish i could do that. I recently did a photo shoot as a present given to me and i loved it now i know this is something id love to do!. I really want to get into Alternative modelling as i love the bad ass pictures that go with it! and the absolutely breathtaking themes you photographers/MUA's & stylists you create.
I'm also a bit of a computer geek so id love to Cosplay or do a shoot with a fairy theme or medieval/ dragon themes!!.
I'm up for pretty much anything and i know if you give me a shot you wont be dissapointed i'm a perfectionist and VERY hardworking. I also take direction very well.
I also have two tattoos which are located on my arm and on my shoulder blade (if you need to know what they are please let me know!).
I ride a motorbike so i know how to Get on and off one
Lastly i would like to bring an escort with me to shots as i am new but once i've been doing it a while i will not require one, If this is something your not comfortable with please let me know.....
So hopefully this is enough information for all you lovely and talented photographers if it isnt then please do not hesitate to message me and i will happily fill you in!.
Thank you very much xx
CreditsMotorbike/Fashion shoot 12/04/2014 - Jerry G63 = Jerry was such a delight to work with from the moment i walked in the door till finish. Being my first professional shoot i was nervous, but Jerry reassured me and kept me confident. After a while the shyness and nerves started to vanish. I would recommend him to anyone he is truly a great pleasure to work with. Works with you and acts like the shoot is a team effort which i think should be. Thank you very much Jerry i look forward to the next!!.
Rehan Qr Photographer
Tanya Marie McGeever Makeup Artist
Phaedra Rose Model
JadeDRed Model
nataliablue Model
Model Mayhem Edu Moderator
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One GM theorized to Ken Rosenthal of FOX Sports that the Dodgers are in a favorable position to land Rays ace David Price. He believes that the Mariners won't give up Taijuan Walker [1] and the D'Backs will say no [2] to including Archie Bradley in a deal. L.A. can't offer a prospect as good as those two, but they can offer some combination of Corey Seager, Joc Pederson, and pitching. Based on yesterday's comments, Rangers GM Jon Daniels doesn't sound as though [3] he's going to make a big play for Price.
For more on this story visit: Zach Links, MLB Trade Rumors [4]