text:
BWW EXCLUSIVE! Darren Criss Comments On GLEE NYC Spin-Off & Previews Upcoming Episodes
Earlier today, popular Glee star and Broadway headliner Darren Criss generously participated in my ongoing InDepth InterView series and offered his candid perspective on many upcoming episodes of the hit musical dramedy series, also briefly commenting on the recent rumors of a re-positioned focus for Glee S5 and S6 or maybe even a full-blown New York City-set spin-off series centering on the characters of Rachel, Kurt and Santana - portrayed by Lea Michele, Chris Colfer and Naya Rivera, respectively - coming up in the future and whether or not Criss/Blaine could become a part of that mix, particularly given his character's long-established romantic affiliation with Kurt.
"I have no idea - I have just heard this rumor myself." Criss candidly said,
"But, listen: wherever they go, I will go," he optimistically opined.
"I'm just happy to be a part of the party!" he added of his continued enthusiasm for the hit FOX series, now in its fifth season.
"But, yeah, I don't know where the show will go, but we have a lot of fun episodes coming up right away...," he teased, before offering a tantalizingly preview of what is to come.
Namely: this week's "A Katy Or A Gaga" episode!
"The Katy/Gaga thing is classic, fun, colorful, crazy GLEE," Criss shares of the ep boasting his performance of Gaga's current worldwide hit "Applause" along with members of the New Directions, as well as the first musical number by AMERICAN IDOL's Adam Lambert via Gaga's "Marry The Night".
Furthermore, Criss says the party doesn't stop there, "Then, we have an episode after that which is called 'The End Of Twerk' and that is really silly and kind of fun, too - you know, it wouldn't be Glee if we didn't sort of have our fun with the cultural pulse with twerking!"
Definitely not with this pop culture button-pusher! Gaga, Katy, Miley - oh, my! So, what other musical icons could be next? Well, Criss offers some "Honesty".
"After that, we filmed an episode which I really loved shooting because it features music by one of my favorite artists - I don't know if I'm allowed to talk about it yet, so let's just say: the piano man."
Yes, indeed - the one and only Billy Joel!
And, what about the long-lost unaired Christmas episode that Ryan Murphy recently teased via his Twitter account? Does that even really exists?
"Sort of...," Criss says elusively.
Sort of?! "I'll just say: sort of," Criss relates before confirming, "Yes. There is a Christmas episode that is unaired."
Don't miss the complete InDepth InterView with Darren Criss all about GLEE, his participation in the new HBO documentary SIX BY SONDHEIM, plus all about his own solo music endeavors, upcoming projects and much, much more coming later this week.
About Author
- SOUND OFF World Premiere Exclusive: Joel Grey In GEORGE M! On THE ED SULLIVAN SHOW
- SOUND OFF: Four Fabulous Features Of This Week's GLEE
- New Rehearsal Sneak Peek Of SOMETHING ROTTEN! Featuring Christian Borle
- Christian Borle & Brian D'Arcy James Talk SMASH Reunion In Rehearsal For SOMETHING ROTTEN!
- GLEE's Darren Criss & Chris Colfer Explain The Klainomenon
- SHAKESPEARE UNCOVERED: SERIES 2 DVD Out Today
- Behind The Scenes With Matthew Morrison In FINDING NEVERLAND Rehearsals
- Ultra-Glam New KINKY BOOTS Academy Awards Social Media Image
- Darren Criss Says Goodbye To GLEE With Emotional Message To Fans
- Lea Michele, Darren Criss & More In Group Photo Of Cast & Crew At GLEE Finale


text:
Hours Of Operation
Monday 8:00am - 5:00pm (Lunch 12:00pm - 1:00pm)
Tuesday 8:00am - 6:00pm (Lunch 12:00pm - 1:00pm)
Wednesday 10:15am - 12:00pm
Thursday 8:00am - 5:00pm (Lunch 12:00pm - 1:00pm)
Friday 8:00am - 5:00pm (Lunch 12:00pm - 1:00pm)
Saturday 9:00am - 1:00pm «« For established patients & their families
MARY'S FAMILY MEDICINE Map/Directions
Gina Landicho-Wicks, MD
16701 Cleveland Street, Suite 210 Patient Records Request? CLICK HERE
Redmond, WA 98052
Phone: (425) 883-8050 Fax: (425) 885-2058
We no longer are accepting new patients.
A friendly reminder: We require that you call us more than 24 hours before your scheduled appointment to make changes, including cancellations. See No Show/Late Cancels for more information.

subset: commoncrawl


text:
- About Us
- Nanotechnology
- News
- Columns
- Products
- Directories
- Career Center
- Nano-Social Network
- Nano Consulting
- My Account
Home > News > Israeli startup develops holographic storage media
June 5th, 2006
Israeli startup develops holographic storage media
The company (Matteris Ltd.) is working on holographic media and a recording/reading driver circuitry and predicts that CD-ROM sized media can store terabytes instead of a maximum of 27-Gbytes, as in Sony's blu-ray DVD.
|Related Links
|Related News Press
Possible Futures
BBC World Service to broadcast Forum discussion on graphene July 6th, 2015
Groundbreaking research to help control liquids at micro and nano scales July 3rd, 2015
Harris & Harris Group Portfolio Company D-Wave Systems Announces 1,000 Qubit Processor and is Discussed in the Economist June 23rd, 2015
Global Nanoclays Market Analysis, Size, Growth, Trends And Segment Forecasts, 2015 To 2022: Grand View Research, Inc June 15th, 2015
Memory Technology
The quantum middle man July 2nd, 2015
Emergence of a 'devil's staircase' in a spin-valve system July 1st, 2015
Graphene flexes its electronic muscles: Rice-led researchers calculate electrical properties of carbon cones, other shapes June 30th, 2015
Buckle up for fast ionic conduction June 16th, 2015
Surfing a wake of light: Researchers observe and control light wakes for the first time July 6th, 2015
Tel Aviv/Tsinghua University project uses crowd computing to improve water filtration: The research, a product of the new TAU-Tsinghua XIN Center, was conducted by 150,000 volunteers at IBM's World Community Grid July 6th, 2015
Transition from 3 to 2 dimensions increases conduction, MIPT scientists discover July 6th, 2015
A Stretchy Mesh Heater for Sore Muscles July 6th, 2015
|The latest news from around the world, FREE
|Premium Products
Only the news you want to read!
Learn More
University Technology Transfer & Patents
Learn More
Full-service, expert consulting
Learn More


text:
- Studio: MCA/Universal Pictures
- Release Date: Mar 26, 1999
- Starring: Jenna Elfman, Matthew McConaughey
- Summary: A satirical look at America's obsession for "reality" television.
- Director: Ron Howard
- Genre(s): Comedy
- More Details and Credits »
Score distribution:
Positive: 10 out of 26
Mixed: 12 out of 26
Negative: 4 out of 26
Howard has a wonderful touch with actors, and almost all of them here have their moments. [26 March 1999, Friday, p.A]
With down-to-earth comic instincts, it simply invests its story with a loud ring of truth.
Neither a revelation nor a total wash, EDtv is instead solid comic filmmaking. I just can't help but think it could have been so much more.
A certain staleness hangs over the proceedings despite the best efforts of the cast and the fun-minded creative team.
But it's also Howard's and his audience's misfortune that a good time can be had by all only if nothing of substance gets said.
Score distribution:
Positive: 2 out of 3
Mixed: 0 out of 3
Negative: 1 out of 3
Jul 9, 2014Ed TV is an amusing comedy drama. Ed is a regular guy who gets his life televised 16 hours a day.
Hijinks ensue and his family are featuredEd TV is an amusing comedy drama. Ed is a regular guy who gets his life televised 16 hours a day.
Hijinks ensue and his family are featured on the show as well. An excellent cast and storyline make
the movie hilarious. The movie is a clever social satire and shows how television affects society. The
movie also shows how television plays a part in people's daily lives, A+.… Expand


text:
SHOW TYPE: Musical
The following is a list of songs in the show or that have been included in the show in various versions:
Main Program
ParadeI Wonder What the King Is Doing TonightThe Simple Joys of MaidenhoodCamelotFollow MeC'est MoiThe Lusty Month of MayThen You May Take Me to the Faira.k.a. Take Me to the FairHow to Handle a WomanThe JoustsBefore I Gaze at You AgainIf Ever I Would Leave YouThe Seven Deadly VirtuesWhat Do the Simple Folk Do?The PersuasionFie on GoodnessI Loved You Once in SilenceGuenevere
Cut prior to opening
The QuestsFace to Face
NBC Renews New Variety Series I CAN DO THAT for Second Season
TV - VIDEO: Bradley Cooper & More in Official Trailer for Netflix's WET HOT AMERICAN SUMMER
MOVIES - Lionsgate & Hasbro to Team to Bring MONOPOLY Game to the Big Screen
FASHION - New Season of PROJECT RUNWAY and Spin-Off Series Heading to Lifetime
MUSIC - VIDEO: Tove Lo Performs 'Talking Body' on CONAN
GEEKS - VIDEO: First Look - Michael Fassbender Stars in STEVE JOBS Biopic
OPERA - BWW Reviews: LA TRAVIATA, a Tragic Love Story Of Pleasure, Passion And Prejudice Is Beautifully Bought to Life by Opera Australia
DANCE - BWW Interview: Robbie and Megan Fairchild Talk Awards Season, Broadway vs. Ballet, and More!
CLASSICAL - Jason Robert Brown Conducts the Des Moines Symphony in Selections of THE BRIDGES OF MADISON COUNTY Tonight


text:
Roving Reporter #102: Brian Piccolo 2010 Inductee
Version 8 and above required to view videos
Uploaded by AirMaria on Jan 11, 2012
Ave Maria! Sports Faith International is a Chicago-based initiative dedicated to inspiring and transforming our culture through the world of sports.ĀĀ It will utilize the best of new and traditional media to feature and encourage the powerful personal testimonies of outstanding athletes at all levels, who are living out their faith on and off the field. Among those inducted in the 2010 Sports Faith International, was Brian Piccolo a Catholic and a professional football player for the Chicago Bears. He died from embryonal cell carcinoma, an aggressive form of cancer. He was the subject of the 1971 TV movie Brian's Song. Piccolo played in the NFL from 1966 to 1969 and scored five touchdowns. Joy Piccolo O'Connell, his wife, received the award and gave us this interview. Ave Maria! To Download Audio go to http://airmaria.com?p=10860
2010 Brian Piccolo Chicago Bears Joy Piccolo O'Connell Sports faith international
0 Comments
Leave a Comment
Most Popular
THE DEVIL HAS SPOKEN - Satanic Temple declares removal of Ten Commandments at Oklahoma capitol a victory Read More
From Christina Aguilera to Angelina Jolie, insider reveals how stars really behave during humanitarian missions Read More
Italy's 'incorruptible' preserved saints remain displayed in churches to be honored Read More
Two Differing Catholic Priestly Views on the SCOTUS Gay 'Marriage' Ruling Read More
Husband and wife, married for 75 years, die in each other's arms Read More


text:
The Vu Villa is divided into two sides - a bar and a restaurant. The restaurant side is family-friendly. Neither side is fancy in appearance but the pizza is really good and the prices are reasonable.
We, for whatever reason never had pizza here. About a year and a half ago, we tried the Vu. Wow, I like my pizza, and I was mad that we never tried them earlier. It is now our go to place for Pizza.! If you haven' t tried the Pizza there, for whatever reason, go get ya some!
Thank you for review! Always happy to hear from customers. We are glad that you had a great experience at the Vu and we look forward to having you back.
We had Taco Pizza and it was great. Lots of fixings on the top and a good thin crust to go with it. Not the nicest place, but a good bar for pizza and a beer.
Thank you for your review! I am glad that you enjoyed your taco pizza. It is a local favorite. Hope you make it back for another visit. Cheers!
Pizza is great. Beer is cold. Staff is friendly. The seating could use some updating, but all in all a good meal with friendly service.
Thanks so much for taking the time to review the Vu Villa! I am glad you had a great experience and enjoyed your pizza.
Just not good pizza. Not much more to say. Unless you're really drunk, dont eat here. Trimbos is close by and it is much better. Dont know how this place stays open.
Register now for free — and start getting automatic notification of new reviews, responding to traveler feedback, adding new photos to your listing and much more.


text:
Top 10 Posts for May 2015 from Stamps of the World. - 1.- Postage stamps and postal history of Romania This is a survey of the postage stamps and postal history of Romania. The principality of Moldavia issued ...
Beautiful Animals by Roeselien Raimond (Part I).
Roeselien Raimond is a passionate photographer – totally in love with animals & nature- who'd like to spend almost every minute of the day on photography.
His main interest is nature, from tiny water drops, fascinating insects, hidden treasures, beautiful scenery to exotic animals.
He also love to take photographs of people, no matter if they're willingly modeling or just passing by, as long as they're interesting …
If you liked this article, subscribe to the feed by clicking the image below to keep informed about new contents of the blog:
Subscribe to: Post Comments (Atom)


text:
SPHealthRulesList.Local Property
SharePoint 2010
Gets an SPHealthRulesList object that represents the SharePoint Health Analyzer Rules list for the farm.
Namespace: Microsoft.SharePoint.Administration.Health
Assembly: Microsoft.SharePoint (in Microsoft.SharePoint.dll)
'Declaration Public Shared ReadOnly Property Local As SPHealthRulesList Get 'Usage Dim value As SPHealthRulesList value = SPHealthRulesList.Local
Property ValueType: Microsoft.SharePoint.Administration.Health.SPHealthRulesList
An SPHealthRulesList object that represents the SharePoint Health Analyzer Rules list for the farm.
The local server is not joined to the farm.
The SPHealthRulesList object returned by the Local property uses unmanaged resources. You are responsible for releasing those resources. One way to do that is to call the Dispose() method when you no longer need the SPHealthRulesList object.
The following example is a console application that queries the Health Rules list for rules that are capable of automatically repairing the problem that the rule is designed to detect. The example enumerates the result set, printing the display text and schedule for each rule to the console.
Imports System Imports Microsoft.SharePoint Imports Microsoft.SharePoint.Administration.Health Module Test Sub Main() Using definitions As SPHealthRulesList = SPHealthRulesList.Local If Not definitions Is Nothing Then ' Write a query to find auto-repair rules. Dim query As SPQuery = New SPQuery() query.Query = "<Where><Eq>" query.Query += "<FieldRef Name='HealthRuleAutoRepairEnabled' />" query.Query += "<Value Type='Boolean'>1</Value>" query.Query += "</Eq></Where>" ' Retrieve list items that satisfy the query. Dim rules As SPListItemCollection = definitions.GetItems(query) ' Print the title and schedule for each item. Dim rule As SPListItem For Each rule In rules Console.WriteLine("{0,-70} {1}", _ rule(SPBuiltInFieldId.LinkTitleNoMenu).ToString(), _ rule(SPBuiltInFieldId.HealthRuleSchedule).ToString()) Next End If End Using Console.Write(vbCrLf + "Press ENTER to continue...") Console.Read() End Sub End Module


text:
Below are top resources on SparkPeople for Detox Diet Plans.
When it comes to dieting, there are more myths and old wives' tales than there are verifiable facts. Here we collect all our best resources for debunking top diet myths so you can stop falling for fads and learn how to use a healthy eating plan t... Read more
A couple decades ago, juicing was something that only overzealously health-conscious people did. You just knew someone was into healthy living if he or she owned a juicer or drank fresh juice regularly. Today, it's much more popular. People... Read more
That white, powdery substance just makes you feel good. You can't get it off your mind, and you keep coming back for more. The more you have it, the more you want it! But even when you try to stay away from it, it finds ways to sneak into your li... Read more
Looking for ways to kick start your heart-healthy lifestyle? Start by looking at your diet. Poor food choices can have a negative effect on your heart, weight and overall health; but making small, sustainable changes to improve your diet can have a l... Read more
In the many years that I have been working with clients who want to lose weight, first as a personal trainer and now as a weight-loss coach, two questions come up over and over again. The first is, ''Will you give me a specific diet to follow... Read more
Is anyone following the Sparkpeople Meal Plans.. and if so, how is that working for you? Any tips?
I've been wanting to try them out for a while now but the meals seem so random. I know you can switch them out for other things but I've never a... Read more
Does anyone here do diet bets?I feel like this will get me motivated bc i hate spending money. Lol.... Read more
Have anybody detox I am doing that this month it supposed to be great for belly fat... Read more
I have finally made a plan. Now, to keep to it. My sister and I are going to go to the gym at lunchtime on Tuesday and Thursday. Then, weekends, I can do an hour walk in the morning or Zumba. Also 15 squats each time I go to the bathroom.. BOOYA!... Read more
Have you fallen into the "diet" trap of everything being zero fat, low cal, lite foods? A little fat helps your body absorb nutrients and stay full longer. Try some hummus or yogurt dip on your veggies, a slice of real cheese. Will up protein too.... Read more
Spicy Lemonade is based on the 'Master Cleanse' Detox but instead of ONLY drinking this wonderful drink, just add it to your healthy diet. Add some lemon juice and a dash of cayenne pepper to warm water. The lemon will help detox your body while the... Read more
Body building sites have great work out and diet plans. Most of the plans include step by step weight training , cardio and diet plans. The diet plans are simple and balanced . They also have other great tips for over all health.... Read more
Caffeine need not be a dirty word when dieting. Our team is for all Sparkers hopelessly in love with their coffee. Drop by the cafe, we're open 24/7 and the coffee is always great!!... Read more
Spring is right around the corner, and as I glance around my home, I see that a thorough cleaning is in order. Dust bunnies are multiplying under my bed, spider webs are glistening on my chandelier, and a layer of dust has settled on all places... Read more
Are you sick of fighting constant tummy troubles? Many people suffer from bloating, discomfort and digestion problems--sometimes for no apparent reason at all. Isn't it time you did something to quit your bellyaching for good (quite literal... Read more


text:
Thanks for redeeming.{{else}}
Success! Thanks for repurchasing.{{/if}} {{else}} {{#if Expired}}
Increase my visibility!{{else}} {{#if IsMultiPack}}
{{#if HasMultiPack}} You have {{MultiPackCount}} top spot(s) left. Now loading you into the search listings... {{else}} You have used all top spots. Now loading you into the search listings... {{/if}}{{else}}
We are loading you into the search listing pages...{{/if}} {{/if}} {{/if}} {{/if}}
{{Current}} just saw you!{{/if}} {{#if LastTopSpotPurchaseIsMulti }} {{#if HasAnyTopSpot}}
{{#if HasFreeTopSpot }} {{ UnclaimedTopSpotFree }} Free {{/if}} {{#if HasPaidTopSpot }} {{#if HasFreeTopSpot }} & {{/if}} {{ MultiPackCount }} {{/if}} Top Spot{{#if Plural}}s{{/if}} Left{{else}}
0 Top Spot{{#if Plural}}s{{/if}} Left{{/if}} {{else}} {{#if HasFreeTopSpot }}
{{ UnclaimedTopSpotFree }} Top Spot{{#if Plural}}s{{/if}} Left{{/if}} {{/if}} {{else}} {{#if HasResults}}
{{Current}} see you now!{{else}} {{/if}} {{/if}}
You can now invite anyone to meet at your favorite Starbucks.
Limited-time feature
39 year old man | Altamonte Springs, FL, USA | Seeking women 30-40 within 35 miles of Casselberry, FL
Cheers..."To good times, new friends and whatever happens next.
Hello thank you for giving my profile a look... The quick facts: I have a good job-(been there for over 6 years). I believe and have been told that I have a good heart and sense of humor. I come from a great family; Mom and Dad are still married- I have a younger sister and an older brother. I am Uncle Mike to my niece and nephew. So what am I looking for? HONESTY -If we cannot trust each other what is the point? (Where is that Deal Breaker Button?) FUNNY/HAPPY- Must have a good sense of humor and/or playful attitude. WHITTY- My second language is playful sarcasm, looking for someone who can keep me on my toes. EASY GOING-Take your time and relax when we can. RESPONSIBLE-You will not have to pay for my past. INDEPENDENT – Someone who WANTS to be with me, but do not NEED to be. Since you have made it this far --- how about a bit more? I grew up in the Southern California mountains (I still try to make it back as often as I can). I moved to WV with my family back in 1996. I moved to Florida in 2002 -- when I finally stopped pretending that I enjoyed shoveling snow. Despite my family being spread across the country, we remain close. I have a amazing "Adopted Family" here in Florida. They are a crazy group of friends that I have picked up along the way. I am fortunate enough to be the unofficial uncle to their kids, the secondary master to their dogs and the friend that their wives don't cringe at. Travel and photography are my two biggest hobbies (and cooking, which I will get to below) good thing they all go together so well. I am always looking for new places to explore (Isn't it convenient we live in Central Florida?). I take mostly nature photography but I will do a wedding or an event for the right friend or price. I also enjoy going camping, hiking, Football is my sport of choice. GO Niners. Growing up with an Italian mother I had no option but to enjoy eating but I have also learned how to cook it. I generally cook from scratch and without recipes. Thanks for reading me.
Camping , Cooking , Dining out , Movies/Videos , Museums and art , Music and concerts , Exploring new areas , Nightclubs/Dancing , Performing arts , Playing cards , Playing sports , Travel/Sightseeing , Watching sports , Wine tasting
Billiards / Pool, Bowling, Cycling, Football, Golf, Hockey, Skiing, Tennis / Racquet sports, Walking / Hiking, Weights / Machines
I exercise 3-4 times per week.
I like Birds, Dogs, Exotic Pets, Fish
A dog guy (Will have at least one someday). I love and am great with most critters.
Middle of the Road
Still a West Coast kid at heart. For my road trips:State Parks-Hot Springs/falls. Clearwater to Venice & The Keys. And for the east Coast St. Augustine & Cocoa Beach. When staying closer to home: Winter Park & Atlamonte Springs work just fine.
Concord University, Athens, WV
Family, Friends, Animals, sunsets, Good food and desserts. TV: CSI, NCIS, Big Bang Theory, How I met your Mother, Survivor. Movies: Physiological thrillers to Comedy-- I am pretty easy going.
I enjoy the beach, hiking, biking, billards bowling, Live events Concerts: Air Shows, Art shows. Photography-Nature mostly. As for sports: Football is my first choice- (49ers). I am getting into Hockey again.
I am sure it was about taking better pictures. Or all about all of those new toys that are out there.
Z{{Cta}} {{#if HasMoreInfo}} ?{{CtaSecondary}} {{/if}}
|What he is looking for
|5'8" (172cms)
|5'2" (157cms) to 5'10" (177cms)
|Body type:
|About average
|Slender, About average, Athletic and toned, A few extra pounds
|Black, Blue, Brown, Grey, Green, Hazel
|Auburn / Red, Black, Light brown, Dark brown, Blonde, Dark blonde
|No Way
|No Way
|Social Drinker
|Social Drinker, Regularly
|Labor / Construction
|No preference
I am currently the office manager for a Construction Company. I have been with my Company for just over 6 years.
|$50,001 to $75,000
|No preference
|Never Married
|No preference
|Have kids:
|Wants kids:
|Not sure
|No preference
|White / Caucasian
|No preference
|Spiritual but not religious
|No preference
|Bachelors degree
|No preference


text:
Amazon.com Review
"Original and imaginative, it conveys a serious, occasionally somber message in a vein of high comedy. I love this book. It is not to be read once through, but to be reread, savored, and pondered."--Edmund Fuller, The Wall Street Journal
"This is a stunningly innovative collection, for readers who like both to chuckle and to think hard."--People


text:
Any inspirational ads from Super Bowl 2015?Posted: January 30th, 2015 | Author: Dana Pascu | Filed under: Advertising, [EN] | Tags: 2015, domestic violence, friskies, superbowl, tvcs, USA | No Comments »
Short answer: Not really. Only these 2 TVCs passed my "less-glitter-more-soul" test.
Will update if case.
If you think you can make a better selection try your luck viewing all the ads here.


text:
Elvis Presley's Black Star Sapphire Ring.... (Total: 4 )
2011 February Beverly Hills Signature Music & Entertainment Auction #7031
|Sold for:
|Sign-in or Join (free & quick)
|Claim Item:
|Sign-in or Join (free & quick)
|Auction Ended On:
|Feb 18, 2011
|Item Activity:
6 Internet/mail/phone bidders
5,254 page views
Heritage Auctions - Beverly Hills
9478 West Olympic Blvd., 1st Floor
Beverly Hills, CA 90212
|Printable auction results for all items in the 2011 February Beverly Hills Signature Music & Entertainment Auction.
Elvis Presley's Black Star Sapphire Ring. Owned and worn by Elvis, this beautiful 14k gold ring features a large black star sapphire ring and eight diamonds in a nugget setting. The black star sapphire was one of Elvis favorite stones, and he purchased many pieces made with black star sapphires in diamonds. This ring was worn by Elvis in the 1970s and later given as a gift to his tour promoter, Tom Hulett. The ring is in Excellent condition and is accompanied by two color 8" x 10" photos of Elvis wearing it during a concert performance as well as a COA from Mr. Hulett.
View large image(s) of this item
Service and Handling Description: Flat Material, Small (view shipping information)
Sales Tax information | Terms and Conditions
Find Auction Prices for Comparable Items:
Sign-in or Join (free & quick) to see the full image


text:
Welcome to Iskra Design! Here you will find portfolios of lettering art in many styles, arranged to invite your browsing. I create custom hand lettering, handwriting and calligraphy for advertising, editorial design, book covers and packaging. The work on this site is unique lettering design created for specific clients or portfolio projects: it is not fonts. Read here about the difference between fonts and custom lettering.
In these portfolios of my work I have created an in-depth resource for the person seeking unique expression through letterforms. You will find collections gathered here by style and by application. The Project category is where you will see lettering and calligraphy applied in print or other media. Some categories overlap, so you may find portfolios repeated in a few places. My newest work usually is posted on my blog, Alphabet Roadtrip.
Please take a look around my world. I hope you will find inspiration for your next project here. Give me a call and let's talk. I'd love to see how we can work together to make something beautiful!


text:
Financial literacy
I just wanted to take the time and thank you for your time today. I know I can pay off all of my stuff, I just needed to hear it from an outsider.
Posted on May 28, 2015
What You Must Know Before Using a Balance Transfer to Consolidate Debt
The days of using balance transfers to get out of debt are not over, but there are certain stipulations you should know before you sign up.
Posted on Apr 16, 2015
How to Know What You Can Afford in a Home
Over the past ten years, we have learned that housing sales contribute enormously to our national economy, but how do those house sales impact our own pocket books and how do we know what we really can afford?
Posted on Apr 03, 2015
The Double Whammy From a New Credit Card
We have heard that applying for credit can impact our credit score. One or two inquiries may have little effect on the numbers, but having several in a year can take its toll. Those applications can have a greater negative effect if they are for credit card accounts.
Posted on Feb 09, 2015
Credit Review Program Gives Military Members the Edge Against Fraud, Misuse
Often targets for bogus financial services, military members, veterans and their families need ways to monitor their credit.
Posted on Jan 12, 2015
Three Examples of Why You Should Check Your Credit Report
We see the commercials telling us to check our credit reports, but many people do not. Here are three examples of why we should take the time to get our reports.
Posted on Sep 15, 2014
Eleven Last Minute Tips for a Great Garage Sale
Some quick advice on how to make your garage sale a winner.
Posted on Aug 29, 2014
Is Your Budget Your Business? It Should Be
People who are successful entrepreneurs know that reducing unnecessary spending can do as much to protect a business's future as generating more sales. The same rules can apply to you as you work to improve your financial profile if you are willing to apply some of those principles.
Posted on Aug 20, 2014
Debt, Depression and Real Answers To Reducing Stress
Sometimes it can be hard to determine what came first; financial problems or depression. However once the debt has become and issue it can increase the amount of hopelessness and anxiety people feel. The good news is, help is available.
Posted on Aug 18, 2014
The Family That Budgets Together...Has a Plan for Their Future
In many families, one person is the designated financial planner. While it may help keep the rest of the family stress free, sharing the process and decisions can be helpful to all everyone. Here is how to get started in your family.
Posted on Aug 07, 2014


text:
Nissan Recalls Infiniti SUVs To Fix Air Bags
Nissan says it's recalling more than 1,800 Infiniti SUVs in the U.S. for an air bag problem that could send shrapnel into the passenger compartment.
GM Ignition Switch Death Count Rises To 29
At least 29 people have died and 27 people have been seriously injured in crashes involving General Motors cars with defective ignition switches.
Toyota Recalls Lexuses In US For Fuel Leak Risk
Toyota is recalling about 423,000 older-model Lexus luxury cars in the U.S. because a gasket can leak fuel and possibly cause a fire.
GM Uses Facebook, Phone calls To Get Recalled Cars Fixed
Despite the heavy publicity surrounding the scandal, many drivers evidently haven't heard of the recall or haven't grasped how serious the defect is…
GM Expert Says 21 Deaths Eligible For Compensation
The death toll from crashes involving GM small cars with faulty ignition switches is at least 21.
Toyota Recalls Pickups To Fix Air Bag Problem
Toyota is recalling about 140,000 Tundra full-size pickup trucks because a plastic trim piece can interfere with the side air bags.
250,000 Recalled Vizio Flat Panel TVs Could Tip Over Unexpectedly
The TVs were sold Best Buy, Meijer, Target, Walmart and online.
106,000 Pounds Of Smoked Sausage Recalled Nationwide
The "Cavanaugh Smoked Sausage" was sold in stores nationwide.
How GM's Ignition Switch Redesign Went Wrong
The switches, though, were too loose, touching off events that led to at least 13 deaths, more than 50 crashes and a raft of legal trouble for the Detroit automaker.
GM Recalls 7.6 Million More Cars Over Ignition Switch Defect
General Motors is recalling at least 7.6 million more vehicles dating back to 1997 to fix faulty ignition switches as the company's safety crisis continues to grow.


text:
Our location guide for Apostolache provides some basic essentials for the more adventurous visitor. A simple location map is provided but also a detailed topography map that shows the location of the nearest places where you can surf, ski or mountain climb (if they are close by). Of course some of these will be at long distances from Apostolache and those far flung spots are provided on the 'nearest' tables. If you are traveling to other cities or towns near Apostolache you will also find weather forecasts for those locations below.
|Other places close to Apostolache:
|Place Name
|1–3 Day Summary
|4–6 Day Summary
|7–9 Day Summary
30 km
|Mostly dry
|Moderate rain (total 12mm), heaviest on Thu night
|Mostly dry
49 km
|Mostly dry
|Moderate rain (total 10mm), heaviest on Thu night
|Mostly dry
62 km
|Mostly dry
|Moderate rain (total 17mm), heaviest on Thu night
|Mostly dry
65 km
|Mostly dry
|Moderate rain (total 12mm), heaviest on Thu night
|Mostly dry
Rimnicu Sarat
70 km
|Mostly dry
|Moderate rain (total 10mm), heaviest on Thu night
|Mostly dry
Outdoor Activities near Apostolache
If you are in Apostolache and would like to go mountain climbing, hiking, skiing or surfing, click below for detailed forecasts.
Ski Resorts close to Apostolache:
|Closest ski resort1
|Sinaia (Romania)
|54 km W
|Second closest ski resort2
|Busteni (Romania)
|58 km W
|Third closest ski resort3
|Azuga (Romania)
|59 km W
|Fourth closest ski resort4
|Predeal (Romania)
|61 km WNW
|Fifth closest ski resort5
|Poiana Brasov (Romania)
|71 km WNW
Mountains close to Apostolache:
|Closest mountain peak1
|Ciucas (Romania)
|43 km NW
|Second closest mountain peak2
|Caraiman Peak (Romania)
|60 km W
|Third closest mountain peak3
|Costila (Romania)
|62 km W
|Fourth closest mountain peak4
|Tampa, Brasov (Romania)
|69 km WNW
|Fifth closest mountain peak5
|Piatra Craiului (Romania)
|86 km W
The above topographic map of Apostolache and the surrounding area has been derived from satellite mapping. The topographic data has been illuminated by a light source corresponding to the position of the sun at mid afternoon in summer. Major roads, railways rivers and other water features are derived from global GIS data.


text:
In our family, we tend to mark holidays with time together out playing. Here are some simple play ideas to get your family outdoors without much hassle. You can do a 4th of July color walk almost anywhere. But to discover the other patriotic play ideas you'll almost need to be local to Orange … Continue Reading
Play Trips and Park Tips
Adventure Playground in Huntington Beach Central Park
Adventure Playground (AP) inside Huntington Beach Central Park is one of 3 true adventure playgrounds in California. The others are in Berkeley … Continue reading
Patriotic OC Playgrounds: Play in Red, White and Blue Glory
Patriotic playgrounds make it feel like the 4th of July anytime of year. There aren't many that are red, white, AND blue. You may just have to … Continue reading
Best Family Travel
Avalon – Top 25 Things to Do in Catalina Island's Popular Destination
We gave you the basics on how to get to Avalon on Catalina Island. As a family, we brainstormed 50 things to do on the island, split between Avalon and Two Harbors. This is only meant to give you some general ideas. … Continue Reading
Road Trip: Abalone Cove Shoreline Park in Rancho Palos Verdes
Abalone Cove Shoreline Park was a wonder-filled adventure for our family on a holiday weekend. I owe my outdoorsy friend, Cindy at CAOpenSpace.org, thanks for turning me on to all that Rancho Palos Verdes Peninsula … Continue Reading
Family Travel: 5 Places To Go If You Only Had a Year in California
If you only had a year in California, what are the top five sights you need to see with your family before you move away? My criteria? Mostly that it needs to be signature California. Something you can't … Continue Reading
Best Hotel in San Diego for Families Isn't a Hotel
Humbly written in their marketing materials, you'll see the San Diego Metro KOA list things like "with over 40 years" or "a third generation family business." You might even skip over it, but when you delve deeper … Continue Reading
Point Reyes Lighthouse Visitor Center Family Travel Tips
Okay, I'm going to share my Point Reyes Lighthouse family travel tips for a successful visit to the visitor center at the point of this National Seashore. Weather First of all, it probably WON'T look like … Continue Reading
Point Lobos State Natural Preserve in Monterey
Point Lobos State Natural Preserve in Monterey is a scenic wonder full of sea life, hiking trails, a cultural museum, and grand views of the Pacific. Trails are totally manageable for families, but most trails … Continue Reading
The Living Desert Zoo and Gardens Displays Sonoran Desert Life
The Living Desert zoo and gardens in Palm Desert feels like you are in the middle of the Sonoran desert in Arizona when, in fact, you are at the edge of its borders just 2 hours from Orange County. I didn't realize … Continue Reading


text:
1996 Plymouth Voyager Q&A
1996 Plymouth Voyager Question: wont run
changed fuel pump filter plugs wires and coil pack now van wont run starts idles real rough and when you give it any gas it dies out. Whel ideling it is real rough - nathan79
2 Answers
Answer 1
Did it run OK before you fixed it? If so, check your work, like check the sparkplug gap and type (cheap ones aren't my choice). If it had driveability problems which you were trying to fix by replacing parts, remember that diagnosis is key, not changing parts hoping to get lucky. I think it's time to take the car to a Chrysler specialist for a diagnosis. If you want to find a specialist, here's our directory link for you: https://repairpal.com/directory?address=16132&car_brand_names=Plymouth - Superbob
Related Items:
Recently replaced battery. Tried to start car, ASD relay began clicking. Replaced it. Cranks, but no start. Attached OBD Code Reader- No error codes. Changed to real time monitoring, car starts and...
Related Content
1. pushrod
2. stevieray1
3. globalhelper
4. Shivers
5. csubak30
6. ziptie12
7. Hal...
8. IsraelS
9. goodguy
10. BrianLankford


text:
Users Online Now:
Who's On?
Visitors Today:
Pageviews Today:
Threads Today:
Posts Today:
Join Our:
GLP Poker Rooms
Check Out:
GiveMeGossip.com - Gossip Forum
Donate To GLP
Adv. Search
Back to Forum
Back to Thread
Message Subject
X Marks the Spot
Poster Handle
Anonymous Coward
Post Content
No its not like that have had one of those way back as well. It's more my stomach, feels raw when I first wake up . Can't hardly eat without it cramping up. Can't drink cold liquids either or eat cold things that also makes it cramp up. Nothing that would constitute an emergency at this particular time tho. Its all upper left abdomen. No bleeding or throwing up, and no fever, so that is why Im not so worried for the moment.
>~* Flutterby Fringe*~<
Do you feel excessively tired? Have you had Mono before? As that can cause upper-left quadrant pain.
Believe it or not bismuth, the active ingredient in Pepto, successful in treating ulcers.
If that is what you have.
Have you noticed others with stomach pain in your area?
Could it be your water?
Well I had the thought about the water also. Never had mono and not really tired just uncomfortable. My filter for my water stuff was time to change didnt have another one so used tap water for about 3 days till I got bottled water. It had this oily film on it I noticed.. so it could have been the water . My bff has been having problems as well with hers acting up also. Tonight the water out of the tap smells like it has a high clorine content. I am also worried about the corexit having seeped into our water supply and they don't filter that sort of stuff out of it.
Need to get stuff I seen for a home made water distiller to make distilled water to drink but that doesn't take care of the bath water tho and skin absorbs chemicals from showers and baths also.
>~* Flutterby Fringe*~<
i gotta ask now:
have you ever tried any probiotics: keifer, kombucha, cultured milk or cheese?
GI issues are frequently ecosystem imbalances and modern medicine mostly don't have a clue about that sorta thing.
and on that note. some past posts speaking or serotonin made want to share: serotonin is primarily used by the *stomach* to increase and decrease it's size and it is ONLY the cells in the stomach that release into to blood stream, no other way, despite what people may think 5htp will NOT help you recover serotonin loss (for folks who like mdma).
turns out tho that adding the right bacteria to the stomach will work. Studies comparing the efficacy of ssri's to pond scum in rats show that the bacteria in the pond scum is more effective...
the we buggers *talk* to the stomach cells.
it's not chemistry. it's communication.
or thats how i see it. i eat living food any chance i get. Thats part of our problem, all the food we eat is dead dead dead.
yet another modern mistake: treating bacteria as the enemy.
Anonymous Coward 9905909
Like the mycorrhiza under the soil, communication.
Health for plants like microflora is health for humans.
They say 97% of our dna isn't even human but other like microbes, bacteria and viruses.
Please verify you're human:
Reason for copyright violation:
Man finds dollar wife signed years after her death
Remember when the schools started having students rat their parents out? Video Reveals Jade Helm Plans For Children
IRS Makes It Illegal For Small Businesses to Help Employees Pay Healthcare Premiums
After children are damaged by vaccines, parents are intimidated and bullied into silence
Wilderness Corridors: Agenda 21 Under A New Name
Big Brother "Pay-by-the-Mile" Track and Tax Driving Scheme Being Rolled Out Now!
Where's Your Place in Jade Helm?
Aluminum, Barium and Strontium: the New Manhattan Project chemtrail sprays
According to a YT channel , every time you drink a glass of water, you are drinking molecules that have previously been urinated from a dinosaur.
More Bans/Censorships In Oregon: Orwellian College Professor Places Ban On Opinions In Class
Researchers in Russia have said that they have found an artifact object that appears to be a 250 million year old microchip.
A recent study has found that the smell of fish can improve critical thinking by arousing suspicion.
The Woolly Mammouth is now many steps closer to becoming a living, breathing reality.
A leaked Whitehall paper suggests that plans to scrap part of the UK's main sickness benefit are being considered
Services such as Paypal, and Itunes have been suspended from processing payments in Greece under the country's new capital control laws.
British Rockstar Shaun Ryder has admitted that he witnessed a UFO hovering outside of his bedroom window
Pharmaceutical giant Johnson and Johnson have developed a new vaccine to protect against AIDS, and have begun testing it on humans
Another Alternative Doctor Found Dead, Police Investigation Underway
How to Tell Someone's Age When All You Know Is Her Name
Liberals passed a bill to change this fish's name because it is "hurtful" and "offensive"
Growing Own Food Greek Man's Secret Weapon Against Economic Meltdown
Cube-Shaped Craft Over El Paso - Amazing Photos
Woman snaps photo of Waffle House prayer
Obama's Proposed Ozone Regulations Would Ban 4th of July Celebrations
Get ready to kiss any home equity you have goodbye
This Flag Represents The Principle, "Fight For What You Believe In."
This Is The Rebel Flag, "You're Either Free Or You're Not."
Disclaimer / Copyright Info
Privacy Policy
Terms Of Use
with questions or comments about this site.
"Godlike Productions" & "GLP" are registered trademarks of Zero Point Ltd. Godlike™
Website Design Copyright © 1999 - 2015 Godlikeproductions.com
Page generated in 0.004s (3 queries)


text:
Charter moves to acquire Time Warner Cable
Tim Fitzsimons
May 26, 2015 And why it may go more smoothly than the failed Comcast-Time Warner Cable merger.
Charter near a deal to buy Time Warner
Adriene Hill
May 25, 2015 It's a cable company-eat-cable-company world out there
The art of keeping — or spoiling — a TV secret
Eliza Mills
Produced by
May 22, 2015 Spoiler alert! Sometimes we enjoy knowing the ending in advance.
David Letterman wears the pants at Worldwide Pants
Sally Herships
May 19, 2015 The production company was crucial when Letterman moved to CBS two decades ago.
It's a Mad Mad Men world for AMC
Nova Safo
May 14, 2015 AMC wants to make the most of the end of "Mad Men."
Slimmer cable bundles rattle media companies
Dan Weissmann
Apr 22, 2015 Content companies say Verizon can't legally offer a package with fewer channels.
NBC announces 'The Wiz' as its next musical
Kai Ryssdal
Mar 30, 2015 Loved NBC's "Peter Pan?" You're in luck.
Cord cutter, or committed to cable? How you watch what you watch
Raghu Manavalan
Mar 27, 2015 Why people keep their cable or move to streaming, and what it costs
Do you know what you're paying for TV?
Nova Safo
Mar 12, 2015 What should be a simple question doesn't always have a simple answer.
Networks battle for morning supremacy, young viewers
Mitchell Hartman
Nov 18, 2014 ABC's "Good Morning America" nails the a.m. formula while NBC's "Today" struggles.


text:
Are you Irmgard Amrein?Claim your profile
Publications (26)93.72 Total impact
Article: Selection for tameness, a key behavioral trait of domestication, increases adult hippocampal neurogenesis in foxes[Show abstract] [Hide abstract]
ABSTRACT: Work on laboratory and wild rodents suggests that domestication may impact on the extent of adult hippocampal neurogenesis and its responsiveness to regulatory factors. There is, however, no model of laboratory rodents and their non-domesticated conspecifics that would allow a controlled comparison of the effect of domestication. Here, we present a controlled within-species comparison of adult hippocampal neurogenesis in farm-bred foxes (Vulpes vulpes) that differ in their genetically determined degree of tameness. Quantitative comparisons of cell proliferation (Ki67) and differentiating cells of neuronal lineage (doublecortin, DCX) in the hippocampus of foxes were performed as a proxy for neurogenesis. Higher neurogenesis was observed in tameness-selected foxes, notably in an extended subgranular zone of the middle and temporal compartments of the hippocampus. Increased neurogenesis is negatively associated with aggressive behavior. Across all animals, strong septo-temporal gradients were found, with higher numbers of proliferating cells and young neurons relative to resident granule cells in the temporal than in the septal hippocampus. The opposite gradient was found for the ratio of DCX/Ki67 positive cells. When tameness-selected and unselected foxes are compared to rodents and primates, proliferation is similar, while the number of young neurons is higher. The difference may be mediated by an extended period of differentiation or higher rate of survival. On the background of this species-specific neurogenic pattern, selection of foxes for a single behavioral trait key to domestication, i.e. genetic tameness, is accompanied by global and region-specific increases in neurogenesis. This article is protected by copyright. All rights reserved. © 2015 Wiley Periodicals, Inc.Hippocampus 01/2015; DOI:10.1002/hipo.22420 · 4.30 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: African mole-rats (family Bathyergidae) are small to medium sized, long-lived and strictly subterranean rodents that became valuable animal models as a result of their longevity and diversity in social organization. The formation and integration of new hippocampal neurons in adult mammals (adult hippocampal neurogenesis, AHN) correlates negatively with age and positively with habitat complexity. Here we present quantitative data on AHN in wild-derived mole-rats of one year and older, and briefly describe its anatomical context including markers of neuronal function (calbindin and parvalbumin). Solitary Cape mole-rats (Georychus capensis), social highveld mole-rats (Cryptomys hottentotus pretoriae), and eusocial naked mole-rats (Heterocephalus glaber) were assessed. Compared to other rodents, the hippocampal formation in mole-rats is small, but shows a distinct cytoarchitecture in the dentate gyrus and CA1. Distributions of the calcium-binding proteins differ from those seen in rodents; e.g., calbindin in CA3 of naked mole-rats distributes similar to the pattern seen in early primate development, and calbindin staining extends into the stratum lacunosum moleculare of Cape mole-rats. Proliferating cells and young neurons are found in low numbers in the hippocampus of all three mole-rat species. Resident granule cell numbers are low as well. Proliferating cells expressed as a percentage of resident granule cells are in the range of other rodents, while the percentage of young neurons is lower than that observed in surface dwelling rodents. Between mole-rat species, we observed no difference in the percentage of proliferating cells. The percentages of young neurons are high in social highveld and naked mole-rats, and low in solitary Cape mole-rats. The findings support that proliferation is regulated independently of average life expectancy and habitat. Instead, neuronal differentiation reflects species-specific demands, which appear lower in subterranean rodents.Frontiers in Neuroanatomy 04/2014; DOI:10.3389/fnana.2014.00039 · 4.18 Impact Factor
Article: The hippocampus of the eastern rock sengi: cytoarchitecture, markers of neuronal function, principal cell numbers, and adult neurogenesis[Show abstract] [Hide abstract]
ABSTRACT: The brains of sengis (elephant shrews, order Macroscelidae) have long been known to contain a hippocampus that in terms of allometric progression indices is larger than that of most primates and equal in size to that of humans. In this report, we provide descriptions of hippocampal cytoarchitecture in the eastern rock sengi (Elephantulus myurus), of the distributions of hippocampal calretinin, calbindin, parvalbumin, and somatostatin, of principal neuron numbers, and of cell numbers related to proliferation and neuronal differentiation in adult hippocampal neurogenesis. Sengi hippocampal cytoarchitecture is an amalgamation of characters that are found in CA1 of, e.g., guinea pig and rabbits and in CA3 and dentate gyrus of primates. Correspondence analysis of total cell numbers and quantitative relations between principal cell populations relate this sengi to macaque monkeys and domestic pigs, and distinguish the sengi from distinct patterns of relations found in humans, dogs, and murine rodents. Calretinin and calbindin are present in some cell populations that also express these proteins in other species, e.g., interneurons at the stratum oriens/alveus border or temporal hilar mossy cells, but neurons expressing these markers are often scarce or absent in other layers. The distributions of parvalbumin and somatostatin resemble those in other species. Normalized numbers of PCNA+ proliferating cells and doublecortin-positive (DCX+) differentiating cells of neuronal lineage fall within the overall ranges of murid rodents, but differed from three murid species captured in the same habitat in that fewer DCX+ cells relative to PCNA+ were observed. The large and well-differentiated sengi hippocampus is not accompanied by correspondingly sized cortical and subcortical limbic areas that are the main hippocampal sources of afferents and targets of efferents. This points to intrinsic hippocampal information processing as the selective advantage of the large sengi hippocampus.Frontiers in Neuroanatomy 10/2013; 7:34. DOI:10.3389/fnana.2013.00034 · 4.18 Impact Factor
Article: Effects of Laboratory Housing on Exploratory Behaviour, Novelty Discrimination and Spatial Reference Memory in a Subterranean, Solitary Rodent, the Cape Mole-Rat (Georychus capensis)[Show abstract] [Hide abstract]
ABSTRACT: A large number of laboratory and field based studies are being carried out on mole-rats, both in our research group and others. Several studies have highlighted the development of adverse behaviours in laboratory animals and have emphasised the importance of enrichment for captive animals. Hence we were interested in evaluating how laboratory housing would affect behavioural performance in mole-rats. We investigated exploratory behaviour, the ability to discriminate between novel and familiar environments and reference memory in the solitary Cape mole-rat (Georychuscapensis). Our data showed that both wild and captive animals readily explore open spaces and tunnels. Wild animals were however more active than their captive counterparts. In the Y maze two trial discrimination task, wild animals failed to discriminate between novel and familiar environments, while laboratory housed mole-rats showed preferential spatial discrimination in terms of the length of time spent in the novel arm. The performance of the laboratory and wild animals were similar when tested for reference memory in the Y maze, both groups showed a significant improvement compared to the first day, from the 3rd day onwards. Wild animals made more mistakes whereas laboratory animals were slower in completing the task. The difference in performance between wild and laboratory animals in the Y-maze may be as a result of the lower activity of the laboratory animals. Laboratory maintained Cape mole-rats show classic behaviours resulting from a lack of stimulation such as reduced activity and increased aggression. However, they do display an improved novelty discrimination compared to the wild animals. Slower locomotion rate of the laboratory animals may increase the integration time of stimuli, hence result in a more thorough inspection of the surroundings. Unlike the captive animals, wild animals show flexibility in their responses to unpredictable events, which is an important requirement under natural living conditions.PLoS ONE 09/2013; 8(9):e75863. DOI:10.1371/journal.pone.0075863 · 3.53 Impact Factor
Article: Habitat-specific shaping of proliferation and neuronal differentiation in adult hippocampal neurogenesis of wild rodents[Show abstract] [Hide abstract]
ABSTRACT: Daily life of wild mammals is characterized by a multitude of attractive and aversive stimuli. The hippocampus processes complex polymodal information associated with such stimuli and mediates adequate behavioral responses. How newly generated hippocampal neurons in wild animals contribute to hippocampal function is still a subject of debate. Here, we test the relationship between adult hippocampal neurogenesis (AHN) and habitat types. To this end, we compare wild Muridae species of southern Africa [Namaqua rock mouse (Micaelamys namaquensis), red veld rat (Aethomys chrysophilus), highveld gerbil (Tatera brantsii), and spiny mouse (Acomys spinosissimus)] with data from wild European Muridae [long-tailed wood mice (Apodemus sylvaticus), pygmy field mice (Apodemus microps), yellow-necked wood mice (Apodemus flavicollis), and house mice (Mus musculus domesticus)] from previous studies. The pattern of neurogenesis, expressed in normalized numbers of Ki67- and Doublecortin(DCX)-positive cells to total granule cells (GCs), is similar for the species from a southern African habitat. However, we found low proliferation, but high neuronal differentiation in rodents from the southern African habitat compared to rodents from the European environment. Within the African rodents, we observe additional regulatory and morphological traits in the hippocampus. Namaqua rock mice with previous pregnancies showed lower AHN compared to males and nulliparous females. The phylogenetically closely related species (Namaqua rock mouse and red veld rat) show a CA4, which is not usually observed in murine rodents. The specific features of the southern environment that may be associated with the high number of young neurons in African rodents still remain to be elucidated. This study provides the first evidence that a habitat can shape adult neurogenesis in rodents across phylogenetic groups.Frontiers in Neuroscience 04/2013; 7:59. DOI:10.3389/fnins.2013.00059
Article: Sustained hippocampal neurogenesis in females is amplified in P66 Shc−/− mice: An animal model of healthy aging[Show abstract] [Hide abstract]
ABSTRACT: Aging is accompanied by poor learning and memory abilities and by decreased hippocampal neurogenesis, a process that is also modulated by oxidative stress (OS). P66(Shc) has recently emerged as a novel mammalian gerontogene able to affect healthspan during aging. Deletion of this gene in mice leads to reduced OS accompanied by decreased incidence of age-related pathologies and reduced signs of behavioral aging. We hypothesized that p66(Shc-/-) mutants might show increased neurogenesis in the hippocampus, a brain region involved in learning and memory processes. To this aim, granule cell number, proliferation, neuronal differentiation, and cell death were assessed in the hippocampus in senescent p66(Shc-/-) [knock out (KO)] and p66(Shc+/+) [wild type (WT)] male and female mice. Spatial learning abilities and spontaneous activity were also investigated in a multifunctional behavioral system-IntelliCages. The behavioral analysis revealed that females in general perform better in spatial learning tasks, with genotype effects being apparent in the activity pattern only. Likewise, all females showed increased neuronal differentiation, whereas increased proliferation was found only in those belonging to the p66(Shc-/-) genotype, indicating that they might be protected from precursor cell loss. The number of dying cells was not affected by genotype or sex; however, all KO mice showed less granule cells than WT. Overall, our data suggest that hippocampal function is protected in the female gender at older age, an effect amplified by reduced OS in the p66(Shc-/-) mutant. © 2012 Wiley Periodicals, Inc.Hippocampus 12/2012; 22(12). DOI:10.1002/hipo.22042 · 4.30 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: The lateral ventricle (LV) of the adult rodent brain harbors neural stem cells (NSCs) that continue to generate new neurons throughout life. NSCs located in defined areas of the LV walls generate progenitors with distinct transcriptional profiles that are committed to specific neuronal fates. Here, we assessed if such diversity of NSCs also exist in the adult common marmoset, a widely used primate species in basic and clinical neuroscience research. We first investigated the 3D distributions of proliferative progenitors and committed neuroblasts in the marmoset forebrain. In addition to these maps, we assessed the spatial presence of divergent progenitor populations based on their expression of defined transcription factors, that is, Dlx2, Pax6, Tbr2, and Ngn2 which are differentially expressed by γ-aminobutyric acidergic versus glutamatergic progenitors in the adult rodent forebrain. In striking contrast to rodents, glutamatergic progenitors were only sparse in neonates and absent from the adult LV, whilst present in the hippocampus. Our analyses highlight major differences in the diversity of NSCs of the marmoset LV compared with rodents and emphasize the need to address NSCs diversity in evolutionary higher order mammals concomitantly to rodents.Cerebral Cortex 04/2012; DOI:10.1093/cercor/bhs085 · 8.31 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Deletion of the p66(Shc) gene results in lean and healthy mice, retards aging, and protects from aging-associated diseases, raising the question of why p66(Shc) has been selected, and what is its physiological role. We have investigated survival and reproduction of p66(Shc)-/- mice in a population living in a large outdoor enclosure for a year, subjected to food competition and exposed to winter temperatures. Under these conditions, deletion of p66(Shc) was strongly counterselected. Laboratory studies revealed that p66(Shc)-/- mice have defects in fat accumulation, thermoregulation, and reproduction, suggesting that p66(Shc) has been evolutionarily selected because of its role in energy metabolism. These findings imply that the health impact of targeting aging genes might depend on the specific energetic niche and caution should be exercised against premature conclusions regarding gene functions that have only been observed in protected laboratory conditions.Aging cell 11/2011; 11(1):162-8. DOI:10.1111/j.1474-9726.2011.00770.x · 5.94 Impact Factor
Article: Comparing adult hippocampal neurogenesis in mammalian species and orders: influence of chronological age and life history stage[Show abstract] [Hide abstract]
ABSTRACT: Adult hippocampal neurogenesis is a prominent event in rodents. In species with longer life expectancies, newly born cells in the adult dentate gyrus of the hippocampal formation are less abundant or can be completely absent. Several lines of evidence indicate that the regulatory mechanisms of adult neurogenesis differ between short- and long-lived mammals. After a critical appraisal of the factors and problems associated with comparing different species, we provide a quantitative comparison derived from seven laboratory strains of mice (BALB, C57BL/6, CD1, outbred) and rats (F344, Sprague-Dawley, Wistar), six other rodent species of which four are wild-derived (wood mouse, vole, spiny mouse and guinea pig), three non-human primate species (marmoset and two macaque species) and one carnivore (red fox). Normalizing the number of proliferating cells to total granule cell number, we observe an overall exponential decline in proliferation that is chronologically equal between species and orders and independent of early developmental processes and life span. Long- and short-lived mammals differ with regard to major life history stages; at the time points of weaning, age at first reproduction and average life expectancy, long-lived primates and foxes have significantly fewer proliferating cells than rodents. Although the database for neuronal differentiation is limited, we find indications that the extent of neuronal differentiation is subject to species-specific selective adaptations. We conclude that absolute age is the critical factor regulating cell genesis in the adult hippocampus of mammals. Ontogenetic and ecological factors primarily influence the regulation of neuronal differentiation rather than the rate of cell proliferation.European Journal of Neuroscience 09/2011; 34(6):978-87. DOI:10.1111/j.1460-9568.2011.07804.x · 3.67 Impact Factor
Article: Different regulation of adult hippocampal neurogenesis in Western house mice (Mus musculus domesticus) and C57BL/6 mice[Show abstract] [Hide abstract]
ABSTRACT: Adult hippocampal neurogenesis (AHN) of laboratory rodents is enhanced by physical exercise in a running wheel. However, little is known about modulation of AHN in wild-living rodent species. The finding that AHN cannot be modulated by voluntary exercise in wild wood mice suggests that AHN may be regulated differently under natural conditions than in laboratory adapted animals. In order to minimize genetic influences, we aimed to investigate the genetically closest wild-living relatives of laboratory mice. Here, C57BL/6 mice and F1 offspring of wild house mice (Mus musculus domesticus) were tested in two different running paradigms: voluntary running and running-for-food--a condition in which mice had to run for their daily allowance of food. In house mice, we found a non-significant trend towards increased numbers of proliferating cells and doublecortin-positive immature neurons in both voluntary runners and runners-for-food. Voluntary running in C57BL/6 mice resulted in a 30% increase in cell proliferation and a pronounced 70% increase in doublecortin-positive cells. C57BL/6 runners-for-food ran as much as voluntary runners, but they showed no enhancement of cell proliferation, a small increase in the number of doublecortin-positive cells and more pyknotic cells compared to controls. Taken together, these findings suggest that motivational aspects of running are critical determinants of the increased cell proliferation in C57BL/6 mice. In contrast, running has smaller and context-independent effects in house mice. The findings imply a difference in the regulation of AHN in C57BL/6 mice and their wild-derived conspecifics.Behavioural brain research 07/2011; 227(2):340-7. DOI:10.1016/j.bbr.2011.07.026 · 3.39 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: The increasing resolution of tract-tracing studies has led to the definition of segments along the transverse axis of the hippocampal pyramidal cell layer, which may represent functionally defined elements. This review will summarize evidence for a morphological and functional differentiation of pyramidal cells along the radial (deep to superficial) axis of the cell layer. In many species, deep and superficial sublayers can be identified histologically throughout large parts of the septotemporal extent of the hippocampus. Neurons in these sublayers are generated during different periods of development. During development, deep and superficial cells express genes (Sox5, SatB2) that also specify the phenotypes of superficial and deep cells in the neocortex. Deep and superficial cells differ neurochemically (e.g. calbindin and zinc) and in their adult gene expression patterns. These markers also distinguish sublayers in the septal hippocampus, where they are not readily apparent histologically in rat or mouse. Deep and superficial pyramidal cells differ in septal, striatal, and neocortical efferent connections. Distributions of deep and superficial pyramidal cell dendrites and studies in reeler or sparsely GFP-expressing mice indicate that this also applies to afferent pathways. Histological, neurochemical, and connective differences between deep and superficial neurons may correlate with (patho-) physiological phenomena specific to pyramidal cells at different radial locations. We feel that an appreciation of radial subdivisions in the pyramidal cell layer reminiscent of lamination in other cortical areas may be critical in the interpretation of studies of hippocampal anatomy and function.Brain Structure and Function 05/2011; 216(4):301-17. DOI:10.1007/s00429-011-0322-0 · 4.57 Impact Factor
Article: Running in laboratory and wild rodents: Differences in context sensitivity and plasticity of hippocampal neurogenesis[Show abstract] [Hide abstract]
ABSTRACT: Adult hippocampal neurogenesis, i.e. the formation of new neurons within the existing neuronal network of the dentate gyrus, is subject to modulation by internal and external factors. Among them, voluntary physical exercise is one of the best investigated positive stimulators of neurogenesis in laboratory rodents. Straightforward translation of the observed running-increased neurogenesis has nourished the commonsensical idea that physical challenges would keep our brains healthy and young. However, several lines of evidence indicate that the tempting assumption that, through physical exercise neurogenesis increases and hence cognition improves, might fall short of more complex effects and interactions. In the present work we argue that motivation may be a key factor in determining whether exercise will positively affect neurogenesis in the hippocampus of laboratory animals. In addition, it has been shown that in genetically heterogeneous wild mouse species hippocampal neurogenesis can be exercise- and context-independent. It appears that in wild rodents adult hippocampal neurogenesis is stabilized to the sum of transient pleasant and aversive stimuli characterizing a natural environment. Variability in the regulation of adult neurogenesis questions if the concept of an improved cognition mediated by a running-increased neurogenesis can be easily transferred to the human condition. The present review surveys the research on exercise and hippocampal neurogenesis in the context of motivation, genetic background and species differences.Behavioural brain research 04/2011; 227(2):363-70. DOI:10.1016/j.bbr.2011.04.027 · 3.39 Impact Factor
Article: Number estimates of neuronal phenotypes in layer II of the medial entorhinal cortex of rat and mouse[Show abstract] [Hide abstract]
ABSTRACT: Modelling entorhinal function or evaluating the consequences of neuronal losses which accompany neurodegenerative disorders requires detailed information on the quantitative cellular composition of the normal entorhinal cortex. Using design-based stereological methods, we estimated the numbers, proportions, densities and sectional areas of layer II cells in the medial entorhinal area (MEA), and its constituent caudal entorhinal (CE) and medial entorhinal (ME) fields, in the rat and mouse. We estimated layer II of the MEA to contain approximately 58,000 neurons in the rat and approximately 24,000 neurons in the mouse. Field CE accounted for more than three-quarters of the total neuron population in both species. In the rat, layer II of the MEA is comprised of 38% ovoid stellate cells, 29% polygonal stellate cells and 17% pyramidal cells. The remainder is comprised of much smaller populations of horizontal bipolar, tripolar, oblique pyramidal and small round cells. In the mouse, MEA layer II is comprised of 52% ovoid stellate cells, 22% polygonal stellate cells and 14% pyramidal cells. Significant species differences in the proportions of ovoid and polygonal stellate cells suggest differences in physiological and functional properties. The majority of MEA layer II cells contribute to the entorhinal-hippocampal pathways. The degree of divergence from MEA layer II cells to the dentate granule cells was similar in the rat and mouse. In both rat and mouse, the only dorsoventral difference we observed is a gradient in polygonal stellate cell sectional area, which may relate to the dorsoventral increase in the size and spacing of individual neuronal firing fields. In summary, we found species-specific cellular compositions of MEA layer II, while, within a species, quantitative parameters other than cell size are stable along the dorsoventral and mediolateral axis of the MEA.Neuroscience 09/2010; 170(1):156-65. DOI:10.1016/j.neuroscience.2010.06.048 · 3.33 Impact Factor
Article: The entorhinal cortex of the Megachiroptera: a comparative study of Wahlberg's epauletted fruit bat and the straw-coloured fruit bat.[Show abstract] [Hide abstract]
ABSTRACT: This study describes the organisation of the entorhinal cortex of the Megachiroptera, straw-coloured fruit bat and Wahlberg's epauletted fruit bat. Using Nissl and Timm stains, parvalbumin and SMI-32 immunohistochemistry, we identified five fields within the medial (MEA) and lateral (LEA) entorhinal areas. MEA fields E(CL) and E(C) are characterised by a poor differentiation between layers II and III, a distinct layer IV and broad, stratified layers V and VI. LEA fields E(I), E(R) and E(L) are distinguished by cell clusters in layer II, a clear differentiation between layers II and III, a wide columnar layer III and a broad sublayer Va. Clustering in LEA layer II was more typical of the straw-coloured fruit bat. Timm-staining was most intense in layers Ib and II across all fields and layer III of field E(R). Parvalbumin-like staining varied along a medio-lateral gradient with highest immunoreactivity in layers II and III of MEA and more lateral fields of LEA. Sparse SMI-32-like immunoreactivity was seen only in Wahlberg's epauletted fruit bat. Of the neurons in MEA layer II, ovoid stellate cells account for approximately 38%, polygonal stellate cells for approximately 8%, pyramidal cells for approximately 18%, oblique pyramidal cells for approximately 6% and other neurons of variable morphology for approximately 29%. Differences between bats and other species in cellular make-up and cytoarchitecture of layer II may relate to their three-dimensional habitat. Cytoarchitecture of layer V in conjunction with high encephalisation and structural changes in the hippocampus suggest similarities in efferent hippocampal --> entorhinal --> cortical interactions between fruit bats and primates.Brain Structure and Function 05/2010; 214(4):375-93. DOI:10.1007/s00429-010-0239-z · 4.57 Impact Factor
Article: A morphologically distinct granule cell type in the dentate gyrus of the red fox correlates with adult hippocampal neurogenesis.[Show abstract] [Hide abstract]
ABSTRACT: Wild red foxes, proverbially cunning carnivores, are investigated for adult hippocampal neurogenesis and morphological characteristics of the dentate gyrus. Adult red foxes harbor almost 15-times more young, doublecortin-positive neurons in their dentate gyrus than domesticated dogs. The number of doublecortin-positive cells corresponds to 4.4% of the total granule cell number, whereas dividing cells amount to only 0.06%. Compared to laboratory mice, proliferating (Ki67-positive) and dying cells are rare, but the percentage of new neurons is quite similar. The numbers of proliferating cells, young cells of neuronal lineage and dying cells correlate. Resident granule cells can be divided into two types with strikingly different morphologies, staining patterns and distinct septotemporal distributions. Small sized granule cells with a nuclear diameter of 7.3 microm account for approximately 83% of all granule cells. The remaining granule cells are significantly larger with a nuclear diameter of 9.4 microm diameter and stain heavily for NeuN. Septally and mid-septotemporally, densely packed small cells dominate. Here, only few large granule cells are scattered throughout the layer. Temporally, granule cells become more loosely packed and most of the cells are of the large type. High rates of neurogenesis are observed in foxes with high numbers of large granule cells, whereas the number of small granule cells does not correlate with any of the neurogenesis-related cell counts. Staining for parvalbumin, glutamate receptor 2/3, GAP-43 and dynorphin shows an anatomical context that is a composite of features common also to other mammalian species. In summary, we report a morphologically distinct granule cell type which correlates with adult hippocampal neurogenesis in the fox. Furthermore, the maturation phase of the young neurons may be prolonged as in other long living species such as primates.Brain research 03/2010; 1328:12-24. DOI:10.1016/j.brainres.2010.02.075 · 2.83 Impact Factor
Article: Hippocampal neurogenesis and cortical cellular plasticity in Wahlberg's epauletted fruit bat: a qualitative and quantitative study.[Show abstract] [Hide abstract]
ABSTRACT: Species-specific characteristics of neuronal plasticity emerging from comparative studies can address the functional relevance of hippocampal or cortical plasticity in the light of ecological adaptation and evolutionary history of a given species. Here, we present a quantitative and qualitative analysis of neurogenesis in young and adult free-living Wahlberg's epauletted fruit bats. Using the markers for proliferating cell nuclear antigen (PCNA), bromodeoxyuridine (BrdU), doublecortin (DCX) and polysialic acid neural cell adhesion molecule (PSA-NCAM), our findings in the hippocampus, olfactory bulb and cortical regions are described and compared to reports in other mammals. Expressed as a percentage of the total number of granule cells, PCNA- and BrdU-positive cells accounted for 0.04 in young to 0.01% in adult animals; DCX-positive cells for 0.05 (young) to 0.01% (adult); PSA-NCAM-positive cells for 0.1 (young) to 0.02% (adult), and pyknotic cells for 0.007 (young) to 0.005% (adult). The numbers were comparable to other long-lived, late-maturing mammals such as primates. A significant increase in the total granule cell number from young to adult animals demonstrated the successful formation and integration of new cells. In adulthood, granule cell number appeared stable and was surprisingly low in comparison to other species. Observations in the olfactory bulb and rostral migratory stream were qualitatively similar to descriptions in other species. In the ventral horn of the lateral ventricle, we noted prominent expression of DCX and PSA-NCAM forming a temporal migratory stream targeting the piriform cortex, possibly reflecting the importance of olfaction to these species. Low, but persistent hippocampal neurogenesis in non-echolocating fruit bats contrasted the findings in echolocating microbats, in which hippocampal neurogenesis was largely absent. Together with the observed intense cortical plasticity in the olfactory system of fruit bats we suggest a differential influence of sensory modalities on hippocampal and cortical plasticity in this mammalian order.Brain Behavior and Evolution 01/2010; 76(2):116-27. DOI:10.1159/000320210 · 4.29 Impact Factor
Article: A reward increases running-wheel performance without changing cell proliferation, neuronal differentiation or cell death in the dentate gyrus of C57BL/6 mice[Show abstract] [Hide abstract]
ABSTRACT: Exercise is one of the best-known stimulators of adult hippocampal neurogenesis, but it is not known if voluntary changes in the intensity of exercise are accompanied by changes in neurogenesis. In this study we investigated whether a reward influences the performance in a running wheel and the rate of cell proliferation, neuronal differentiation and cell death in C57BL/6 mice. Mice had free access to a running wheel during the first week of the experiment. In the second week, animals were rewarded for their performance and compared to normal voluntary running and control mice. A reward significantly increased the performance by 78% when compared to the non-rewarded performance of the first week. The performance of the non-rewarded runners remained relatively constant. Fourteen days of exercise significantly increased cell proliferation by 27% and the number of doublecortin immunoreactive cells by 46%. A reward and the associated increase of performance did not modulate proliferation, cell death or the number of cells entering the neuronal lineage. We suggest that, in C57BL/6 mice, either exercise increases adult hippocampal neurogenesis to a ceiling value, which is reached by a performance at or below the level achieved by voluntary wheel running, or that a possible positive effect of increased running-wheel activity is balanced by stress resulting from rewarded running, which is no longer performed on a strictly voluntary basis.Behavioural brain research 07/2009; 204(1):175-81. DOI:10.1016/j.bbr.2009.06.002 · 3.39 Impact Factor
Article: No effect of running and laboratory housing on adult hippocampal neurogenesis in wild caught long-tailed wood mouse[Show abstract] [Hide abstract]
ABSTRACT: Studies of adult hippocampal neurogenesis (AHN) in laboratory rodents have raised hopes for therapeutic interventions in neurodegenerative diseases and mood disorders, as AHN can be modulated by physical exercise, stress and environmental changes in these animals. Since it is not known whether cell proliferation and neurogenesis in wild living mice can be experimentally changed, this study investigates the responsiveness of AHN to voluntary running and to environmental change in wild caught long-tailed wood mice (Apodemus sylvaticus). Statistical analyses show that running had no impact on cell proliferation (p = 0.44), neurogenesis (p = 0.94) or survival of newly born neurons (p = 0.58). Likewise, housing in the laboratory has no effect on AHN. In addition, interindividual differences in the level of neurogenesis are not related to interindividual differences of running wheel performance (rs = -0.09, p = 0.79). There is a correlation between the number of proliferating cells and the number of cells of neuronal lineage (rs = 0.63, p < 0.001) and the number of pyknotic cells (rs = 0.5, p = 0.009), respectively. Plasticity of adult neurogenesis is an established feature in strains of house mice and brown rats. Here, we demonstrate that voluntary running and environmental changes which are effective in house mice and brown rats cannot influence AHN in long-tailed wood mice. This indicates that in wild long-tailed wood mice different regulatory mechanisms act on cell proliferation and neurogenesis. If this difference reflects a species-specific adaptation or a broader adaptive strategy to a natural vs. domestic environment is unknown.BMC Neuroscience 05/2009; 10:43. DOI:10.1186/1471-2202-10-43 · 2.85 Impact Factor
Article: Gene expression profiling of neurochemically defined regions of the human brain by in situ hybridization-guided laser capture microdissection[Show abstract] [Hide abstract]
ABSTRACT: Laser capture microdissection (LCM) permits isolation of specific cell types and cell groups based upon morphology, anatomical landmarks and histochemical properties. This powerful technique can be used for region-specific dissection if the target structure is clearly delineated. However, it is difficult to visualize anatomical boundaries in an unstained specimen, while histological staining can complicate the microdissection process and compromise downstream processing and analysis. We now introduce a novel method in which in situ hybridization (ISH) signal is used to guide LCM on adjacent unstained sections to collect tissue from neurochemically defined regions of the human postmortem brain to minimize sample manipulation prior to analysis. This approach was validated in nuclei that provide monoaminergic inputs to the forebrain, and likely contribute to the pathophysiology of mood disorders. This method was used successfully to carry out gene expression profiling and quantitative real-time PCR (qPCR) confirmation from the dissected material. When compared to traditional micropunch dissections, our ISH-guided LCM method provided enhanced signal intensity for mRNAs of specific monoaminergic marker genes as measured by genome-wide gene expression microarrays. Enriched expression of specific monoaminergic genes (as determined by microarrays and qPCR) was detected within appropriate anatomical locations validating the accuracy of microdissection. Together these results support the conclusion that ISH-guided LCM permits acquisition of enriched nucleus-specific RNA that can be successfully used for downstream gene expression investigations. Future studies will utilize this approach for gene expression profiling of neurochemically defined regions of postmortem brains collected from mood disorder patients.Journal of Neuroscience Methods 03/2009; DOI:10.1016/j.jneumeth.2008.11.012 · 1.96 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Substantial production of new neurons in the adult mammalian brain is restricted to the olfactory system and the hippocampal formation. Its physiological and behavioural role is still debated. By comparing adult hippocampal neurogenesis (AHN) across many mammalian species, one might recognize a common function. AHN is most prominent in rodents, but shows considerable variability across species, being lowest or missing in primates and bats. The latter finding argues against a critical role of AHN in spatial learning and memory. The common functional denominator across all species investigated thus far is a strong decline of AHN from infancy to midlife. As predicted by Altman and colleagues in 1973, this implies a role in transforming juvenile unpredictable to predictable behaviour, typically characterizing mammalian behaviour once reproductive competence has been attained. However, as only a fraction of mammalian species has been investigated, further comparative studies are necessary in order to recognize whether AHN has a common unique function, or whether it mediates species-specific hippocampal functions.Biology letters 11/2008; 5(1):141-4. DOI:10.1098/rsbl.2008.0511 · 3.43 Impact Factor
Top Journals
University of Zurich
Zürich, Zurich, Switzerland
- Institute of Veterinary Anatomy


text:
Full Paper
Surface-Plasmon Assisted Energy Conversion in Dye-Sensitized Solar Cells
Article first published online: 15 APR 2011
DOI: 10.1002/aenm.201000080
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Advanced Energy Materials
Volume 1, Issue 3, pages 415–421, May, 2011
Additional Information
How to Cite
Ding, B., Lee, B. J., Yang, M., Jung, H. S. and Lee, J.-K. (2011), Surface-Plasmon Assisted Energy Conversion in Dye-Sensitized Solar Cells. Adv. Energy Mater., 1: 415–421. doi: 10.1002/aenm.201000080
Publication History
- Issue published online: 12 MAY 2011
- Article first published online: 15 APR 2011
- Manuscript Revised: 10 MAR 2011
- Manuscript Received: 22 DEC 2010
- dye-sensitized solar cells;
- surface plasmon resonance;
- core-shell nanoparticles
In this study, the effect of plasmonic core-shell structures, consisting of dielectric cores and metallic nanoshells, on energy conversion in dye-sensitized solar cells (DSSCs) is investigated. The structure of the core-shell particles is controlled to couple with visible light so that the visible component of the solar spectrum is amplified near the core-shell particles. In core-shell particle – TiO2 nanoparticle films, the local field intensity and light pathways are increased due to the surface plasmons and light scattering. This, in turn, enlarges the optical cross-section of dye sensitizers coated onto the mixed films. When 22 vol% of core-shell particles are added to a 5 μm thick TiO2 film, the energy conversion efficiency of DSSCs increases from 2.7% to 4.0%, in spite of a more than 20% decrease in the amount of dyes adsorbed on the composite films. The correlation between core-shell particle content and energy conversion efficiency in DSSCs is explained by the balance among near-field effects, light scattering efficiency, and surface area in the composite films.


text:
Premier Program JOIN FREE!
Premier Members Enjoy:
Exclusive pricing and volume discounts
3% BACK on every purchase
Fast & FREE shipping on thousands of items
Save time with your account manager
Over 7 million products to choose from
Quick & easy PO terms for qualifying accounts
Buying for a business, school, or organization?Save even more with our FREE Premier Program for business professionals. CONTINUE
Steelcase 2-Drawer Mobile Classic Payback File/File Pedestal
Steelcase 2-Drawer Mobile Classic Payback File/File Pedestal
Weights & Dimensions
|Product Type: Vertical filing cabinet
|Style: Contemporary
|Hardware Finish: Platinum
|Primary Material: Manufactured wood
|Additional Materials: Laminate
|Number of Items Included: 1
|Wheels Included: Yes
|Drawers Included: Yes
|Locking: Yes
|Hanging File Compatible: Yes
|Commercial Use: Yes
|Country of Manufacture: Canada
About the ManufacturerSteelcase began in 1912 as The Metal Office Furniture Company in Grand Rapids, Michigan. They received their first patent in 1914 for a steel wastebasket -- a major innovation at a time when straw wastebaskets were a major office fire hazard. That led to metal desks, and they've led the way with product and service innovations ever since. Today, their portfolio of solutions address the three core elements of an office environment: interior architecture, furniture and technology.
Steelcase 2-Drawer Mobile Classic Payback File/File Pedestal
Questions & Answers (1)
"Hi, how many drawers does the cabinet have?" asked by Linda
Still have questions about this product? We're here to help
Customer Reviews
Tell Us What You Think!
Tell us what you think about this product. It will help us provide you with better products in the future and help your fellow shoppers make better purchases.Write the first review


text:
- Age / Gender:
- 26, Male
- Location:
- Brazil
- Joined:
- 9/13/09
- All Stats >
User Statshot
- Community Stats
Level 18 Blank Slate
Normal Whistle
Ranked as Scout
Contact Info / Websites
- Skype
- vitor_tamberlini
Latest News
É só você colocar o jogo, e dependendo dele, eu passo algumas dicas de medalhas!
Recent Game Medals
Box Smasher 5 Points Destroy 150 boxes Medal Stats.
Two Hundo 5 Points Score 200 points Medal Stats.
SECRET MEDAL 100 Points Unlock this medal to see it's details. Medal Stats.
Time Attack 50 Points A new lap record! Medal Stats.
Brutal 10 Points You probably poke dead animals with sticks, too. Medal Stats.
Save The Day 100 Points Well aren't you a fucking hero?! Medal Stats.
Bruckheimer 50 Points Make a big explosion! Medal Stats.
SECRET MEDAL 25 Points Unlock this medal to see it's details. Medal Stats.
SECRET MEDAL 25 Points Unlock this medal to see it's details. Medal Stats.
Overkill 25 Points When winning just isn't enough... Medal Stats.
Total Medals Earned: 5,327 (From 845 different games.)
Favorite Movies
What About a Man? Rated 4.3317 Stars Six people and a dog share ideas and prejudice. Comedy - Original Mario Twins (official) Rated 4.0546 Stars Yeah, you like that, IDIOT. Comedy - Parody SMB: Game Over (1up) Rated 4.3204 Stars Oh gawd... I hope that's rain... *wink* Comedy - Parody Average Man Rated 4.3519 Stars Video game characters singing to music?? Haha, we've never seen THAT before!!!! AHAHAHAHAA Music Video
Favorite Games
Epic Battle Fantasy 2 Rated 4.3784 Stars Battle through waves of enemies... again. Now with upgrades and stuff! Adventure - RPG Beat Universe Rated 4.1151 Stars Click, hold, and drag to the beat of many different songs! Rhythm Klikwerk Rated 3.8728 Stars Remove all the items as quickly as possible, as you are told ... Rhythm Amorphous+ Rated 4.4655 Stars Wield the Splatmaster3000, fend off hoards of Glooples, and earn Rewards! Action - Other
Favorite Audio
|Wings ~P~
|Video Game Loop
|Basshuter-ish Loop (Take 2)
|Trance Loop
|Tribute to Trance (Krussi)
|Trance Song
|-'+ Secret Melody +'-
|Trance Song
Latest Shared Creations
Level Added to more for Less is More? May 12, 2013. Load Level
FREE MEDAL Added to level for Gap Monsters Jan 10, 2013. Load Level
enter map name Added to map design for Hurry Up Bob: Map Editor Dec 21, 2011. Load Level
enter map name Added to map design for Hurry Up Bob: Map Editor Dec 21, 2011. Load Level
My Pumpkin Added to pumpkins for Carve n' Share Sep 10, 2011. Load Level
my skin Added to skins for Skincraft Jun 2, 2011. Load Level


text:
Upload Photo
Hudson Valley celebs on the scene
See recent photos of celebrities with Hudson Valley connections out and about around the world.
Peek into Long Island's most lavish homes LI people on the move! Promotions, new jobs Puppies from Southampton Animal Shelter 26 surprising relics from WWII Photos: 97 celebrities remember life on Long Island Long Island and New York City's top photos 18 things only Long Islanders would understand 58 signs you're from Suffolk LI notable deaths Notable Long Island celebs Recent LI fires Recent LI mug shots


text:
Thanks for redeeming.{{else}}
Success! Thanks for repurchasing.{{/if}} {{else}} {{#if Expired}}
Increase my visibility!{{else}} {{#if IsMultiPack}}
{{#if HasMultiPack}} You have {{MultiPackCount}} top spot(s) left. Now loading you into the search listings... {{else}} You have used all top spots. Now loading you into the search listings... {{/if}}{{else}}
We are loading you into the search listing pages...{{/if}} {{/if}} {{/if}} {{/if}}
{{Current}} just saw you!{{/if}} {{#if LastTopSpotPurchaseIsMulti }} {{#if HasAnyTopSpot}}
{{#if HasFreeTopSpot }} {{ UnclaimedTopSpotFree }} Free {{/if}} {{#if HasPaidTopSpot }} {{#if HasFreeTopSpot }} & {{/if}} {{ MultiPackCount }} {{/if}} Top Spot{{#if Plural}}s{{/if}} Left{{else}}
0 Top Spot{{#if Plural}}s{{/if}} Left{{/if}} {{else}} {{#if HasFreeTopSpot }}
{{ UnclaimedTopSpotFree }} Top Spot{{#if Plural}}s{{/if}} Left{{/if}} {{/if}} {{else}} {{#if HasResults}}
{{Current}} see you now!{{else}} {{/if}} {{/if}}
You can now invite anyone to meet at your favorite Starbucks.
Limited-time feature
25 year old woman | Quakertown, PA, USA | Seeking men 25-31 within 50 miles
What we do in life echoes in eternity
Is not that I don't want to read/answer e-mails, I just haven't upgraded my subscription. I don't know if it's alright but my IG name is the same one as the one I use for here. Everyone who knows me will consider me as a very nice, hard working, and fun person. I love helping others. I love laughing at everything, if you really get to know me you will know how much of a weirdo I am (in a good way). I love others making me laugh and I think that's a very important part when looking for a special someone. I love sports, 99% of the time I love playing them instead of watching them. Probably, the only sport that I will watch, because I really want to, is tennis. I am a tennis player and I love it. However, if I am with friends or other person and they are watching any other sport on TV I will actually get really into it. I am a very adaptable person. I am not picky, only with food (not a fan of spicy food.) I love reading...I I am a big fan of astronomy. I feel like a geek now. I love hanging out with my girls at Starbucks and catching up. I am also the least girly in my group of friends. I like video games, anime, alternative sports, rock...etc. I love giving advice to anyone who needs it. I work out when I don't have classes or work. I do Zumba, yoga and weights. When the weather is nice i like running around the town. In summer, one of my favorite things is swimming, it's so good. I love dogs, I have a miniture schanuzer, Yordie, and I take care of him all the time, he gets spoiled by me, though not in the food category, I would never give my dog something that he definitely shouldn't have. I love traveling...it's so great to see new places, different faces and beautiful scenery. Movies... i am not that picky, I would see anything but if it's not good then i will never watch it again. I like scary movies and so my girlfriends like to go to the movies with me and watch them because i would laugh at the scenes they would scream at and that makes them less nervous. That is many things but not all about me.... now, who i'm looking for: This is my first time doing this. I decided to give it a shot and i'm sure my friends would laugh at me but... i really don't care. I have been in and out of relationships never really having something concrete. I am a bit tired of that and really want to have someone that can be there for me like i will be there for that person. I love a person who is family oriented because I happen to love mine with all my heart. I don't have a "type" of guy. I like to get to know the guy and see him for who he is and of course like i say...if you are going to be with someone you two should be attracted emotionally, physically and sexually. Just putting it out there. Emotionally I mean someone who shares the values I do and that is sweet and can be honest and laughs at anything. Physically I mean someone that i can workout with or that we can go on a hike or skiing or swimming...anything, Sexually you can figure it out. I don't like guys who smoke. I also like a person who has a goal...or many, just like I do. If you think that's you then go ahead and get in touch ^_^
Alumni connections , Camping , Coffee and conversation , Cooking , Dining out , Hobbies and crafts , Movies/Videos , Music and concerts , Exploring new areas , Nightclubs/Dancing , Playing sports , Travel/Sightseeing , Video games , Volunteering
Aerobics, Auto racing / Motorcross, Basketball, Bowling, Cycling, Dancing, Martial arts, Other types of exercise, Running, Soccer, Swimming, Tennis / Racquet sports, VolleyBall, Walking / Hiking, Weights / Machines, Yoga
I exercise 3-4 times per week.
I have Dogs
I have a min schanuzer, he is 2 1/2 years old and his name is Yordie. He is the best dog anyone could have.
Middle of the Road
I love going to Colombia, it's beautiful. I went to WV and it's so beautiful! I went camping there for 2 weeks and hiked, went into caves and did white water rafting, amazing place. I also like Montreal and Ocean City, MD
Favorite movies: Gladiator, Big Fish, Sin City, Inglorious Basterds, Bridesmaids, Hangover, The Lord of the rings, The family stone, Memoirs of a Geisha, Feast of love, Fast and furious... Favorite music: Old rock, Alternative rock, spanish...etc
For fun I like reading a good book, playing sports specially tennis. I like playing with my dog. I love being with my friends, going out dancing with them, having a get-together or going out to bars. I like anything to do with astronomy.
Last thing I read was a book about positive intelligence (pretty good) I also read all the Fifty Shades of Gray books (uhm..yeah, good). That's about it. School books I guess, things like Chemistry and Microbiology
Z{{Cta}} {{#if HasMoreInfo}} ?{{CtaSecondary}} {{/if}}
|What she is looking for
|5'2" (157cms)
|5'7" (170cms) to 8'11" (271cms)
|Body type:
|Slender, Athletic and toned
|Black, Blue, Brown, Grey, Green, Hazel
|Dark brown
|Auburn / Red, Black, Light brown, Dark brown, Blonde, Dark blonde
|No Way
|No Way
|Social Drinker
|Never, Social Drinker
|No preference
I currently go to college and work part time to help pay for my studies.
|$25,001 to $35,000
|Less Than $25,000, $25,001 to $35,000, $35,001 to $50,000, $50,001 to $75,000, $75,001 to $100,000, $100,001 to $150,000, $150,001+
|Never Married
|Never Married
|Have kids:
|Wants kids:
|Definitely, Someday, Not sure
|Latino / Hispanic
|Latino / Hispanic, White / Caucasian, Other
I am originally from Bogota, Colombia. I am an US citizen and I have been living here for 10 years. I also have some Irish background really far back in my ancestry and my great grandfather was from Burgos, Spain.
|I'll tell you later
|No preference
|English, Italian, Spanish
|Some college
|Some college, Associates degree, Bachelors degree, Graduate degree, PhD / Post Doctoral
I am a Biotechnology major and hopefully I will end up with a PhD in Genetic Engineering...that's my goal.


text:
35 points
More About Points »
Chicago, IL
Recent Activity
Question Asked:
Need to find manual on complete tune up and repair.,
Question Asked:
My car does not start during or just after a rain, what could be getting wet that could cause this??
Question Asked:
I replaced and rechecked the gap and plugs which are fine, but the 135 show a misfire. I replaced the thermastat & radiator as well all with in the month. Now it bogs in morning starting for ten minutes and then is fine.
Answer Ranks
This week's top 10
|1 pushrod
|6 ziptie12
|2 stevieray1
|7 Hal...
|3 globalhelper
|8 IsraelS
|4 Shivers
|9 goodguy
|5 csubak30
|10 BrianLankford


text:
5 (0) 4 (0) 3 (0) 2 (1) 1 (0)
2 stars 2/5 Stars Average score of 1 user reviews spread across 1 releases and 0 DLC
Disappointing that this Micro Machine style game isn't great. 0
When I was a kid I used to enjoy playing Micro Machines 2 with a few friends of mine. We'd gather together at the guy's house – he owned the Mega Drive version that had a weird feature allowing you to plug joypads into the game cart itself – and get down to some four player sessions on the miniature top down arcade racer. It was a game that always resulted in laughter as you knocked and bashed your buddies off pool tables, knocked them into sinks or drove them into trees. Due to the camera mecha...0 out of 0 found this review helpful.
This edit will also create new pages on Giant Bomb for:Beware, you are proposing to add brand new pages to the wiki along with your edits. Make sure this is what you intended. This will likely increase the time it takes for your changes to go live.
Comment and Save
Until you earn 1000 points all your submissions need to be vetted by other Giant Bomb users. This process takes no more than a few hours and we'll send you an email once approved.