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Find a Glass Artist
Welcome to our complete Members Directory where you can find details of all our current members. Joining as a member automatically entitles you to a listing in this Directory, where you can provide a biography, upload photos of your work, list exhibition information and provide details of how people can get in touch.
To browse ALL our members without filters, simply click on 'APPLY'. To filter your selection select from the drop down menus and this will only show you those members that meet the criteria you have selected. If you know exactly who you are looking for, please enter their LAST name into the name search field to find them.
Susan Sinclair creates kiln formed, pâte de verre, and cast glass works. She is inspired both by colours one finds in nature and her background in archaeology. Her use of glass powders allows the flexibility of creating unique colours and including texture in her work. Her recent work is focused on building forms from components of sintered glass.
Kiln formed, pâte de verre, and cast glass.
Jan Singleton specialises in contemporary stained glass and unique fused glass panels made to commission.
My work is predominately figurative in origin and addressess, through the qualities of glass, the themes of the Figure in Environment and the Human Condition. I am particularly interested in symbolisim within a composition and the play between the drawn image and Three Dimensional forms. I work to Private & Public Commision and exhibit both Nationally and Internationally
I am currently studying Design Crafts (BAhons) specializing in blown glass at De Montfort University in Leicester.
Catherine is a contemporary applied artist, specialising in kiln fused glass and sandblasting. She comes from a small rural village in Hertfordshire. Her work is inspired by the love for her home, and the natural landscape around her.
She fuses multiple layers of hand drawn images on to glass and etches into the surface, experimenting with the transparency and clarity of vision. She enjoys manipulating the surface qualities of glass, by using etching techniques, to accentuate features and establish more texture and depth within her work. Catherine creates glass for interiors, integrating the beauty of the landscape within the home; from small personalised etched pieces, to larger fused glass panels.
I am a maker who is excited by the qualities of blown glass. I blow glass into and around found object such as wood and scrap metal. Often I will cut and shape the wood before blowing the coloured glass into the void I have created. I love the way the glass becomes restricted after blowing so that it will only fit back into the space created for it. I experiment with colour and inspiration from the work can be found in nature such as the due drops in the early morning on a tree branch.
Originally a biochemist Chrissie re-discovered the challenge of experimentation with fused glass, silver stain and enamels. During her recent studies at Glyndwr University, Chrissie used hand-cut coloured glass or sandblasted float glass to translate the similarities between water and glass. Her sculptural forms are displayed in gardens, backlit with solar LEDs.


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Veteran Horcoff, Ducks agree to one-year contract
Veteran forward Shawn Horcoff and the Ducks agreed on a one-year contract worth $1.75 million Wednesday night. Horcoff, 36, played with Dallas the last two seasons and had 11 goals and 18 assists in 76 gamees. A 12-year performer with Edmonton until 2013-14, Horcoff has 180 goals and 316 assists in 949 NHL games. Horcoff can play

subset: commoncrawl


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Southside Johnny Wednesday 27th October 2010 Southside Johnny and the Asbury Jukes performing at Liverpool O2 Academy Liverpool, England
The 'Luther' actor is one of the hot favourites to take over from Daniel Craig.
Perry made more than any other musician this year including rival Taylor Swift and boyband One Direction.
Mumford and Sons launch their video for newest single 'The Wolf', featuring footage from Bonnaroo.
Filming has begun on the all-female reboot of the classic comedy and now we've been given a sneak peek at the ladies' uniforms.
Bully have just unveiled their debut album 'Feels Like' and now the four-piece have launched an audio for their first single 'Milkman'.
Iggy made her feelings about 'Pretty Girls' clear on Sunday, but has Britney Spears fired back?


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2006 Saab 9-3 Q&A
2006 Saab 9-3 Question: Is this a fuel pump issue or an electrical problem? (shuts off while driving)
The car shuts off while driving. Happens more between 4th and 5th gear, but has happen at a slower speed. The steering column locks and the car can't steer to pull off road. After sitting a while, it will start, while pumping gas pedal. I have had experience with fuel pump & fuel injector failure for GMC trucks, and they will not start once the truck dies. So I am unsure if it is really fuel pump or fuel injector. I am unsure if it is a electrical or sensor problem pertaining to the fuel supply. The Gearbox, engine, abs errors all come on. - Saab06wagon
0 Answers
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Take advantage of this special offer at Harley Street, 3 RadioFrequency sessions for £99 only.
We use the most modern technology when the subject is body shape, our super power tripolar machine gives you a great result in a short amount of time.
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Star Tracks
Urban feels the beat while performing at an NFL event in Baltimore. Plus: Jessica Alba, Simon Cowell & Demi Lovato, Queen Latifah, Sofia Vergara and more
Credit: Limelight Pictures
Published: Friday Sep 06, 2013 | 07:00 PM EDT
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- Kim Kardashian West: 'I Don't Do Fillers or Botox When Pregnant'
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Big Crazy Family Adventure
Sun 9 pm | 8c
An Idiot Abroad
Tues 9pm | 10c
Watt's World
Tues 10 pm | 9c
An Idiot Abroad: Singing in the Streets 02:26
Big Crazy Family Adventure: Bodi & Taj's Top 5 02:59
Niagara Falls
Zak sees a tall man in a blue hat standing behind Aaron at Point Sur lighthouse.
I See an Admiral 02:02
Aaron's Vlog: USS Hornet 02:00
Zak Gets a Feel for Amargosa 02:06
MacArthur's Paranormal Vortex 01:38
Recap: Sacramento Tunnels 03:44
Clowns and Mannequins, Oh My! 01:45
Whaley House Investigation 01:40
Point Sur Plan 01:51


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(as of 2012)
As a Harvard student at Urbana 93, Tom was compelled to give his whole life to student ministry and global missions. Since then, he has planted a student movement in Mongolia with the International Fellowship of Evangelical Students, helped plant 16 new InterVarsity chapters as the Regional Director for the central U.S., written a book published by InterVarsity Press, and spoken to thousands about missions. He currently serves as the Vice Chairman of the Board for Wycliffe Bible Translators and is the Lausanne International Deputy Director for North America.
We do Urbana because there is a need for Urbana. As we look around the world, there is urgency in challenging this generation to engage globally, to grasp biblical foundations of mission, and to discern vocational calling in the midst of the world's needs.
God has a mission. God has acted in history—and is still acting now—to reconcile people from every nation and all of creation to himself. He is the primary agent of his mission. He began his mission, and he continues to work it out in greater love and power than we can imagine.
As we celebrate the growth and initiative of the Global South, as we commit ourselves to humble servant-hood, is there still a place for us in God's global mission? Yes!
Leslie Newbigin wisely suggests that the North American Church must "learn afresh what it means to bear witness to the gospel from a position not of strength but of weakness."
I asked her a question as our time concluded, "If there's one thing you tell this generation of students and young adult
When we read about Jesus sending the 72, we love the evangelistic fervor.
The New Normal in missions presents exciting opportunities. But three things will make this journey much harder than we might think. 1. Perceived Power Loss...


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Summer School 2015 -- June 15 - July 17
No school July 3rd in observance of Independence Day.
Summer School 2015 -- June 15 - July 17
No school July 3rd in observance of Independence Day.
After School Tutoring
After School Tutoing with Mr. Boden will be in the library tutoring all levels of math. Mr. Sanchez will be in Room 227 covering all levels of math. Ms. Marissa P will coordinate the Fitness Center for her tutees. Mr. Kurdyla and Mr. Meyers will cover math and English in the Olguin Campus Library, Mon. thru Thurs. There is an application process and free snacks are provided. The applications can be picked up in the Business Academy or from each teacher participating in the tutoring program.
2014 - 15 Student Behavior & Dress Codes (Click here)
Acceptable behavior, clothing and accessories rules apply to all students.
Athletic Tryouts
Every student athlete must get a physical prior to trying out for any sport in the Fall, Winter or Spring. The information and applications that you need for all sports tryouts are attachments in this email. Click on this headline for more information.


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Clanton Carter Farmer
Position: RB
Height: 5-11 Weight: 175 lbs.
Born: September 8, 1953 in St. Louis, MO
High School: Bassett
College: Oregon (school history) (Farmer college stats)
Weighted Career AV (100-95-...): 0 (14747th overall since 1950)
Other SR Links: College Football at Sports-Reference.com
Promote your website or business by sponsoring this page for $5 on Pro-Football-Reference.com. Your message will replace this ad.
Output includes all games from 1920 to 2014.


text:
Cannes: Koch Media Takes Action Thriller 'Drop' (Exclusive)
The in-development feature will be the next project from "Vehicle 19" director Mukunda Michael Dewil.
Koch Media has picked up all German rights for Drop, an in-development action thriller from Mukunda Michael Dewil, whose last feature was the Paul Walker-starrer Vehicle 19 from sales group K5 International.
Silke Wilfinger and Moritz Peters of Koch Media negotiated the deal with K5 International's Daniel Baur.
Koch bought the project solely based on Dewil's screenplay for the project, which is set on Table Mountain in Cape Town, South Africa. The plot involves terrorists who kidnap the U.S. Vice President and trap him in a cable car hanging half a mile up the mountain. They demand the delivery of the Cullinan Diamond, the world's largest diamond, within 45 minutes or the cable will be cut. The only one who can save the VP is special ops officer and expert base jumper James Conner.
"We knew from the moment we read it that we had to come on board such a pure piece of guilt-free entertainment," said Wilfinger and Peters of Koch Media. "Mukunda has delivered edge of your seat thriller script that will have German audiences in its grip from beginning to end."
Dewil and K5 International are currently casting the film and are first introducing the project to buyers in Cannes.
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The Encyclopedia of Caribbean Religions
Volume 1: A-L; Volume 2: M-Z
Awards and Recognition:
Honorable Mention for the 2014 Dartmouth Medal, awarded by the American Library Association�s Reference and User Services Association (RUSA); also named to the 2014 Outstanding References Sources list by RUSA.
The essential resource for religions of the Caribbean
The Encyclopedia of Caribbean Religions is the definitive reference for Caribbean religious phenomena from a Caribbean perspective. Generously illustrated, this landmark project combines the breadth of a comparative approach to religion with the depth of understanding of Caribbean spirituality as an ever-changing and varied historical phenomenon. Organized alphabetically, entries examine how Caribbean religious experiences have been shaped by and have responded to the processes of colonialism and the challenges of the postcolonial world.
Systematically organized by theme and area, the encyclopedia considers religious traditions such as Vodou, Rastafari, Sunni Islam, Sanatan Dharma, Judaism, and the Roman Catholic and Seventh-day Adventist churches. Detailed subentries present topics such as religious rituals, beliefs, practices, specific historical developments, geographical differences, and gender roles within major traditions. Also included are entries that address the religious dimensions of geographical territories that make up the Caribbean.
Representing the culmination of more than a decade of work by the associates of the Caribbean Religions Project, The Encyclopedia of Caribbean Religions will foster a greater understanding of the role of religion in Caribbean life and society, in the Caribbean diaspora, and in wider national and transnational spaces.
"Both the content and perspective of The Encyclopedia of Caribbean Religions make it a special work. It fills a huge gap left by existing reference sources. Enthusiastically recommended."--Booklist
"This absorbing exploration of various major themes and topics concerning Caribbean religions is rich with text, photographs, and illustrations; and quite comprehensive."--Library Journal
"A tour de force."--Neil Armstrong, The Gleaner
"This is a significant work in Caribbean scholarship and will undoubtedly take its rightful place on the bookshelves of libraries everywhere to assist researchers and essayists, from high school to university."--The Caribbean Camera Newspaper
"This encyclopedia covers an impressive scope of material. Useful for students and scholars alike. Recommended."--Choice
"Easily the most comprehensive and impressive encyclopedic work on religions in the Caribbean. The impressiveness of the work derives from its bringing together the expertise of a host of scholars working on a broad spectrum of religious traditions, topics, and issues. It should become the source of first resort for anyone who wants to explore most aspects of religion in the Caribbean."--The Americas: A Quarterly Review of Inter-American Cultural History
"The most thorough publication to date on this topic. This is a highly recommended resource for public, community college and university libraries."--Philosophy and Religion
To order online:
To order by phone:
(800) 621-2736 (USA/Canada)
(773) 702-7000 (International)
Related Titles
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Edited by Matthew L. Harris and Newell G. Bringhurst
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Rashad Shabazz


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Gainesville, VAUSA 20155
April 15, 2013
My name is Aaron Rodriguez and I am seeking for a community where to expand my social circle. Most people find that in church but us atheist cant fake it.
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#11 of 1143
Delray Beach, FL
Comment, Like, Favorite
Expert Printing and Assembly
Shipping Within 2 - 3 Business Days
Millions of Satisfied Customers
Winter Sunset
Michelle Wiarda
Painting - Watercolor
I painted this North Carolina winter scene from a photo. I love the way that the late afternoon light painted the tree tops gold.
August 10th, 2010
Viewed 2,207 Times - Last Visitor from New York, NY on 07/07/2015 at 7:10 PM
Sales Sheet
More from Michelle Wiarda
Walland, TN - United States
Beautiful winter scene Michelle! Love that barn. l/f
Vail, AZ - United States
Michelle, I love the mood of this rustic old barn, winter snow and sunlit trees...great depth as well....excellent work! F/L Jerry
Fort Collins, CO - United States
Beautiful color and composition! l/f
Simpsonville, SC - United States
I love this so much
Frankfurt Am Main, He - Germany
Great composition and details, Michelle. V/F
Toronto, ON - Canada
Amazing! I thought it's a photo from the thumbnail! What a beautiful painting! F/L
Thanks Oiyee!
Bucharest, Ro - Romania
Mesmerizing winter scene, Michelle. The light you achieved to render is simply stunning and so special. Marvelous painting ! f,l
Thank you Ana! I appreciate your kind words and support! :-)
Lake Worth, FL - United States
Lovely painting with the golds and whites Michelle! We added our Like! Celebrate life, Debra and Dave
Thanks very much Debra and Dave!!
Delray Beach, FL - United States
Thank you very much to Barbara, the art collector! Thank you Blair, Lazaro and Petko!
Razgrad, Ra - Bulgaria
Congratulations on your sale!
La Plata, Bu - Argentina
Calgary, AB - Canada
Gorgeous painting!! Congrats on your sale!!
Binghamton, NY - United States
Gorgeous winter scenery, congratulations on your sale!
Thanks Christina!
Hatfield, PA - United States
LOVE this artwork so much! Can not wait to hang it in our home! Michelle you are very talented and I am the lucky one!
Thank you Barbara!
Delray Beach, FL - United States
Many, many thanks to the art collector!! :-)
Budapest, H - Hungary
Excellent artwork.Congratulations on your sale.
Thank you Odon!
Shady Cove, Or - United States
Wow! Gorgeous, I can feel the chill of the wind, love the golden sunlight too! l/f
Thank you Diane!
San Lorenzo, CA - United States
This is just so, so beautiful, michelle!!!! :)))fv
Thanks very much Laurie!
Delray Beach, FL - United States
Many thanks to the art collector, and to all of you for your kind words! Thank you one and all!!
Budapest, H - Hungary
Congrats on your sale.
Winfield, IL - United States
Congratulations on your sale, Michelle, beautiful artwork!
Philadelphia, PA - United States
Congrats on your sale!!!
San Francisco, CA - United States
Beautiful work, congrats on your sale! f/v
Selah, WA - United States
Congrats Michelle Beautiful scene
Ocala, FL - United States
Fantastic! Such great detail.
St. George, UT - United States
Delray Beach, FL - United States
Thank you ALL for your kind comments, and support!!! :-)
Delray Beach, FL - United States
Thank you so very much to the art collector from North Carolina! I truly appreciate it! :-)
Colfax, CA - United States
I ♥ barns - especially in winter settings - this is beautiful! v/f
Berlin - Germany
!!Congrats on your sale! GREAT WORK!!
Tower City, PA - United States
Beautiful country scenery!!! Congrats on your sale!
Shreveport, lo - United States
i love this painting, it is well done..congrats
Kelowna, BC - Canada
Congrats on your sale Michelle:)
Loveland, CO - United States
Beautiful! Congratulations on your $ale Michelle!
Morehouse, MO - United States
Absolutly beautiful!! Congratulations on your sale! :D
Colorado Springs, CO - United States
I love the touch of sunlight! This is gorgeous! Congratulations on your sale!
W. Melbourne, FL - United States
Congrats on your sale of this beauty!
Neerlandia, Al - Canada
Thanks very much, Johanna!!
Cedar Rapids, Ia - United States
WOW !!! This is a masterpiece to me as I love watercolors so mudh. Yes the trees are magically golden. Perfect.Tha barn is done perfectly. Thanks for your support on comment. Hugs,Marsha F&V
Thanks so much Marsha!
Anaheim, CA - United States
Beautiful artwork, Michelle
Thank you so very much!
Cary, NC - United States
Beautifully done Michelle! It looks so cozy and inviting... great place to hibernate for the winter : )-
Yes I agree, great location for hibernation! Thanks so much Jean-Marie!
Delray Beach, FL - United States
Thank you all so much for your kind comments!
Benton, AR - United States
This is spectacular!! I love Winter scenes!!
Simpsonville, SC - United States
i love your art , love this very much, i am from nc. ben
Evansville, WI - United States
Really fabulous piece. Love it!
Thanks Diane!
Brookline, MA - United States
Such beauty Michelle ... love it!
Thanks Juergen!
Delray Beach, FL - United States
Thank you all so much for you positively kind comments! They mean the world to me.
West Valley, Ut - United States
This is a great painting!! You have mastered watercolor! I love this one! Great job!
Azuga, PH - Romania
Wonderful landscape...cery well done...
Silicon Valley, CA - United States
Well done watercolor piece, Michelle! Great captured the details and beautiful color contrast! Thanks for your comments on my "Knocking on Heaven's Door" and "Boats in front of the Buildings I"!
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Beverly Hills, CA (United States)
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text: The Nila Zaila LED Deluxe Tungsten Light Kit includes the light you need in place of those hot and hungry 50W tungsten fixtures. Add the flexibility of the Nila holographic lens system and you have a fixture that's capable of being both a studio stalwart and a workhorse in the field. The Zaila's flexible AC/DC inputs make it especially useful for ENG applications.


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Oil, Gas and Consumable Fuels
Company Overview of Sequitur Energy Resources, LLC
Company Overview
Sequitur Energy Resources, LLC acquires, owns, and develops oil and gas properties. The company was incorporated in 2013 and is based in Dallas, Texas.
350 North Saint Paul Street
Suite 2900
Dallas, TX 75201
United States
Founded in 2013
Key Executives for Sequitur Energy Resources, LLC
Sequitur Energy Resources, LLC Key Developments
Sequitur Energy Resources, LLC plans to acquire and develop oil and gas assets in the continental United States. Acon Investments, L.L.C and The Pritzker Organization, LLC announced their investment in Sequitur Energy Resources. Bernard Aronson, Founding Partner at ACON, said, "We look forward to working with our partners at TPO and Sequitur to acquire additional upstream assets. We have great confidence in the Sequitur team based on our successful experience building Mariner and we welcome the partnership and added value of our longtime friends at TPO in this venture."
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Walsh, Andrew (2010) Mobile phones in the library at the University of Huddersfield. In: SCONUL Conference 2010 , 16-18 June 2010, The Queens, City Square, Leeds. (Unpublished)
|PDF - Accepted Version
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|Conference or Workshop Item (Poster)
|Z Bibliography. Library Science. Information Resources > ZA Information resources
Z Bibliography. Library Science. Information Resources > Z719 Libraries (General)
|Computing and Library Services
Computing and Library Services > Centre for Innovation in Information Services
School of Education and Professional Development > Centre of Lifelong Learning and Social Justice > Technology Enhanced Learning Research Group
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text:
"We are making efforts to inform the growers about the new technologies. We are providing training to farmers. We are trying to increase the production of the fruit with such initiatives," said Ahmad.
Abdul Ahad Bhat, an apple grower, said that the training proved to be beneficial for them as they got to know about the new technologies.
"The training is quite beneficial as we have been informed about new technology, which is better than what we used before. The production will be of high quality. They also informed us about which branches to cut. This was a very good programme," said Bhat.
Apple farmers at these camps are being trained at the workshops and they are told about the pruning of the trees, the use of manure and oil paste.
The apple industry in the Kashmir valley is the backbone of the state's economy contributing billions of rupees from the export of the fruit to the other parts of the country and abroad.


text:
Police focus on speed limits, ticket revenue during tough times
Speeding 'cushion' may dwindle due to recession
USA Today
The recession may be claiming a new victim: the 5-10-mph "cushion" police and state troopers across the USA have routinely given motorists exceeding the speed limit.
As cities and states scramble to fill budget gaps with revenue from traffic citations, "not only are the (speeding) tolerances much lower, but the frequency of a warning instead of a ticket is way down," says James Baxter, president of the National Motorists Association, a Wisconsin-based drivers' rights group that helps its members fight speeding tickets.
"Most people, if they're stopped now, are getting a ticket even if it's only a minor violation of a few miles per hour," Baxter says. He cites anecdotal evidence of drivers being pulled over at slower speeds.
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text:
@figuerres: HDMI can do 4K@60Hz
native apps please
it was ok, not spectacular but worth the time
SSD space is still pretty expensive, and you'd be pretty crazy to even attempt at storing anything that has to run or compile on a HDD
3 hours ago, blowdart wrote
Disk space is cheap now :)
Even w3bb0 upgraded to Windows 7, I believe
it doesn't seem all that useful at first, it feels very specialized to solve a specific problem
same here, I experienced the same with a friend's phone, where the camera would lock up and the menu would freeze and not return to the main screen
21 hours ago, MasterPi wrote
I can't trust Android for the basic stuff like using it as a phone. Friend has a Nexus - for a while I couldn't figure out why he never picked up my phone calls the first time I call. Then he showed me: he does receive the calls, but sometimes the buttons for accept and reject don't work (the visual is there, but nothing captures the interaction) so he's left tapping hopelessly on a button.
...and at least, the iPhone feels the most complete of all 3 OSes.
there is Thunderbolt
0. make a list like this? :)
did most
static reflection? how does that work? I see runtime Reflection there
Apr 15, 2014 at 1:48 PM, wkempf wrote
In your case, "static reflection" may be better. http://www.digitaltapestry.net/blog/reflecting-on-code
Keep in mind that reflection is slow, whether it's runtime reflection or static reflection. It's best to find ways to cache the results and not use reflection every time.


text: Do Women Have A Responsibility When Men Misbehave? July 31, 2013 San Diego Mayor Bob Filner and New York mayoral candidate Anthony Weiner have apologized for their poor behavior. Host Michel Martin asks the beauty shop ladies, what responsibility - if any - women bear when men behave badly? Writers Danielle Belton, Bridget Johnson and Connie Schultz weigh in. Listen Loading… 17:35 Playlist Download Embed Embed Close embed modal <iframe src="http://www.npr.org/player/embed/207292641/207292634" width="100%" height="290" frameborder="0" scrolling="no">


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The WEEKLY STANDARD podcast with staff writer Michael Warren on the Hillary Clinton book interviews.
This podcast can be downloaded here. Subscribe to THE WEEKLY STANDARD's iTunes podcast feed here.
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I just wrote a piece for The Federalist on a sex seminar at Colgate University on "consent" in sexual relationships. The event brought students together for late-night discussion of their sexual predilections, which the organizers encouraged with just one moral guideline: consent. Here's a swatch from the piece: Even as we denounce any kind of [Read More...]
Josh Barro: "Stamp Out" Those Who Disagree with LGBT Advocates
My friend Andrew Walker and I just wrote a piece for National Review entitled "'Stamp Them Out': On Josh Barro and the New Sexual Moralism." Here's what it's about: Last night, New York Times reporter Josh Barro tweeted out a disturbing message: "Anti-LGBT attitudes are terrible for people in all sorts of communities. They linger and oppress, and we need to stamp [Read More...]
Your Neo-Pagan Neighbor and the Gospel
If you want to write a tsk-tsk piece on American culture, the present moment is your muse. It's a bit bewildering, really, not only for an evangelical like myself but for most anyone who values traditional things. We are all our grandparents now. I didn't watch the Grammys (much), but I'm more or less aware [Read More...]
3 Takeaways from Shocking Study on Planned Parenthood & Teen Pregnancy
This report is nothing short of stunning. According to the Christian Post, when Planned Parenthood clinics close up shop, teen pregnancies drop like a rock. Here's what a recent Texas-based study found: For decades, PPFA has publically maintained that it serves a key healthcare role for the American public by educating teens on "safe sex," providing [Read More...]
The Bride Wore White–But Why?
Newsweek is running a piece, "MySpace Generation Brides Go for Sexy, Not Virgin" that chronicles the sexualization of weddings and offers this concise statement of where things are: "In response, sociologists say, the sexier dresses and the handoff of pin-up pictures—which was introduced into the wedding prep about three years ago—are ways to add spark [Read More...]


text:
Copying by photographic means of plates having coded audio and video information of a very fine structure. Use is made of an aromatic diazosulphide as light-sensitive system, wherein, after exposure, a metal nuclei image is produced by contact with metal salt, which metal nuclei image is at or below the surface and which is intensified by means of physical development to an externally reflective and, as such, readable image.
1. A method of making copies of a carrier of video and/or audio information where the information is present in the form of blocks of variable length separated by areas of variable length all located in a single plane, said blocks of variable length and areas of variable length forming together an information track in the form of a spiral or of concentrical circles, said method comprising exposing to light, through a mask having the desired structure, a light-sensitive material comprising a support having thereon a layer containing as a light-sensitive compound an aromatic diazosulfide of the formula ##STR3## wherein R is alkyl or aralkyl, X is a substituent and n is an integer from 0 to 5 inclusive, treating said exposed light-sensitive material with a water soluble mercury salt or a mixture of a water soluble mercury salt and a silver salt and moisture to form, with the light-reaction product of said light-sensitive compound, a physically developable nuclei metal image of mercury or of silver amalgam on the exposed areas of said light-sensitive material and then developing said light-sensitive material by treatment with a stabilized physical developer containing an aqueous solution of a metal salt, a reducing agent for said metal salt capable of causing said metal salt to deposit free metal on said nuclei metal image and a compound capable of preventing reduction in solution of said salt, the intensity of exposure of said light-sensitive material to light being so chosen that said nuclei image is formed at a distance between 0 and 0.3 μm below the surface of said layer and the time of development is of sufficient duration to cause said free metal deposition on the nuclei image to grow out of said layer.
The invention relates to a method of making copies of information tracks on carriers, more specifically of information carriers of a spiral structure, in which sound and/or video information is stored in the form of frequency-modulated or phase-modulated signals and which structure is assembled from blocks of a variable length which lie in the same plane, separated by areas of a variable length which also lie in a same plane. This kind of information tracks which are described in United Kingdom Patent Specification No. 1,391,541 has a very fine structure; in practice the length of said blocks is in the order of 1 μm and their width is approximately 0.3 μm.
From U.S. Pat. Specification No. 3,381,085 it is known to make copies by photographical means of information tracks to which coded pictures are applied in the form of a spiral track with variable light transmission, which is written by means of a modulated electron beam. Such an information track has a rather coarse structure. Reproduction thereof by photographic means furnishes no difficulties whatsoever.
It appeared, however, that information tracks of the kind described in United Kingdom Patent Specification No. 1,391,541 cannot be copied by photographic means without additional measures.
Dispersion of light during exposure and the occurrence of deflection phenomena may result in annoying background noise.
The usual photographic emulsions on the basis of silver halide are too coarse-grained to enable the reproduction of the fine details of the information track without loss. Even emulsions of this kind with a very fine grain, the so-called Lippman emulsions appeared to be unsuitable for this purpose.
The occurrence of deflection phenomena, which is associated with the fact that the wavelength of the light used for making the copy is of the same order of magnitude as the pictures to be copied was experienced as annoying with various systems, among which some molecular dispersion light-sensitive systems, such as material containing an aromatic diazosulphonate and which, after exposure, is brought into contact with a solution containing mercurous ions and, optionally, silver ions, which results in mercury or silver amalgam nuclei which can be physically developed. Apart from this it appeared that the diazosulphonates were insufficiently diffusion-resistant so that a large part of the definition of the original would have got lost.
In addition it is actually far from obvious to make copies by photographic means of information tracks of the above-mentioned kind, such as, for example, obtained in accordance with the method described in United Kingdom's Patent Specification No. 1,447,066. In accordance with this method there is applied to an information carrier of disc form a photoresist which, due to rotation of the disc relative to a punctiform radiation source, a radiation beam supplied by a laser in particular is intermittently exposed and not exposed during the variable periods which correspond to the information whereafter the photoresist is developed and the required information track is etched.
Thus the information track consists of an embossed picture. If a reproduction is made hereof by photographic means a picture is obtained in the carrier which extends across substantially the entire thickness of the carrier. It is far from certain that hereby the entire video and sound information would be fully transmitted.
Dutch Patent Application No. 7,609,610 which has not yet been published describes a method in accordance with which copies of information carriers having an information track of spiral or of concentric circular form wherein sound and/or video information in the form of frequency-modulated or phase-modulated signals is stored in the form of blocks of a variable length which lie in the same plane, separated by areas of a variable length, which are also in a same plane are obtained by means of the photographic system which is known per se from United Kingdom Patent Specification No. 1,227,116. Herein use is made of light-sensitive material consisting of a substrate layer which comprises a light-sensitive compound which is of the type which furnishes after exposure a light-reaction product which is able to react with mercurous ions in the presence of moisture and, preferably, also in the presence of silver ions whilst separating mercury or silver amalgam which is deposited in the form of a metal nuclei image which can be physically developed, which light-sensitive compound is an aromatic diazosulphide of the structure ##STR1## wherein the benzene ring may comprise one or more substituents X and wherein R is a whether or not branched alkyl or aralkyl group, by developing until a density below D = 1 above the basic density of the carrier.
By developing in this manner to a relatively low density the above-mentioned annoying diffraction phenomena are suppressed.
The best reproduction of the information copied in this manner is obtained when it is read in reflection. This require a reflective surface either in the form of a provision in the reproducing apparatus, or in the form of a coating on the copy of the information carrier, for example a vapour-deposited aluminium coating. When reading the copy the transparent portions will reflect the light substantially unweakened whereas the picture portions will absorb twice: once for the incident light and once for the reflected light.
In accordance with the invention it was found that with the photographic system known from United Kingdom Patent Specification No. 1,227,116 it is possible to obtain a copy in the form of an external picture pattern which can be read directly in reflection from above.
The conditions for obtaining the external picture by means of photographic systems whilst using a light-sensitive material, consisting of a support in which there is a light-sensitive compound of the type that can react with mercurous ions in the presence of moisture, and preferably, also in the presence of silver ions whilst separating mercury or silver amalgam which is deposited in the form of a physically developable nuclei image, are described in United Kingdom Patent Specification No. 954,208. Therein, however, the object was the production of printed wiring patterns in an additive manner, wherein the details are generally much greater than those of the information tracks in accordance with United Kingdom Patent Specification No. 1,391,541. As therein an external growth of metal takes place it has been assumed so far that the resolution was limited to fairly coarse details. However, it appeared possible to improve the resolution by means of special measures to such an extent that even submicron details can be depicted.
It is in the first place important that a nuclei image is obtained which is located at or at most near the surface of the carrier. This location can be controlled; it is determined by the diffusion rates (a) of the light reaction product and (b) of the ion of the nuclei image metal.
As the light reaction product of the benzene diazosulphides used is very diffusion-resistant the location can be influenced by varying the concentration of the reaction partners and by varying the nature of the indiffusing solvent. The concentration of the light reaction product is coupled with the intensity of the exposure. By means of a proper choice of the intensity of exposure, of the concentration of the nuclei image metal ion and of the nature of the solvent the depth of the nuclei image can be controlled. Thus, when using a hydrophilic carrier a solvent mixture consisting for at least 50 vol. % of water and for the remainder of a water-soluble organic solvent is chosen for the nuclei image metal ion or mixture of metal ions.
The nuclei image is allowed to grow by means of stabilized physical development until it grows out of the carrier. The external metal image obtained then has a nice reflective appearance.
In order to obtain an external image pattern which corresponds without loss in quality with the information track of the type discussed above and which is immediately readable in reflection the nuclei image should be at a distance of not more than 0.3 μm within the carrier surface or at the carrier surface.
It is then possible to obtain already a reflective image by a very small growth by means of physical development whereby the details of the image are preserved.
In accordance with the invention a copy of an information carrier of the type described above which is directly readable in reflection is obtained owing to the fact that use is made of a light-sensitive material consisting of a support containing a light-sensitive compound which is of the type that furnishes, after exposure, a light reaction product which is able to react with mercurous ions in the presence of silver ions whilst separating mercury or silver amalgam which is deposited in the form of a physically developable metal nuclei image, which light-sensitive compound is an aromatic diazosulphide of the structure ##STR2## wherein the benzene ring may contain one or more substituents X and wherein R is a whether or not branched alkyl or aralkyl group, the intensity of the exposure and the concentration of the nuclei image metal ion being chosen so that the nuclei image is formed at a distance between 0 and 0.3 μm below the carrier surface, which nuclei image is subsequently developed with a stabilized developer until it has grown out of the carrier. The following example may serve to illustrate the invention:
Contact copies of chromium-on-glass masks comprising a test picture having lines narrower than 0.5 μm were reproduced in a pressure cassette at a pressure of 2 atm. on light-sensitive material by exposure for 9 seconds with a 125 W HPR high-pressure mercury lamp at a distance of 80 cm.
The light-sensitive material consisted of a 2 μm thick coating of saponified cellulose acetobutyrate on a 1.65 mm thick glass plate which material was made sensitive to light by treating it with a solution of 0.1 mole/l 3.5 dichloro-4-dimethylaminobenzenediazo-t-butylsulphide in ethanol. Another substrate, for axample a 1 mm thick methacrylate plate can be used instead of glass. A 120 μm thick superficially saponified cellulose triacetate film may also be used as starting material.
The exposed plate was immersed for 2 seconds in a solution which contained per liter of solvent (6 : 2 : 1 parts by volume of water-isopropanolethylacetate):
0.0025 mole Hg2 (NO3)2
0.025 mole AgNO3
0.01 mole HNO3
The nuclei image obtained was at a depth of 0.2 μm.
After rinsing for 2 seconds in the same solvent physical development took place for 20 seconds in a solution in water, containing per liter:
0.1 mole ferrous-ammoniumsulphate
0.04 mole ferric nitrate
0.05 mole citric acid
0.05 mole silver nitrate
0.008% "Armac 12 D"
0.008% "lissapol N"
The reflection spectrum of these images was determined.
The maximum reflection appeared to be in the wave length range 500-550 nm. Half of the maximum reflection was found at 420 and 720 nm.
The result of the method is a copy which contains all details of the original and wherein the image is reflective.
Qualitatively the result is comparable with that obtained in accordance with the prior Dutch Patent Application 7,609,610 which has not yet been published.
"Armac 12 D" is a cationic wetting agent which consists for approximately 90% of dodecyl amineacetate, for approximately 9% of tetradecyl amineacetate and for the remainder of acetates of higher amines.
"Lissapol N" is a non-ionic wetting agent consisting of a condensation product of ethylene oxide and alkyl phenols.
Patent Citations
Non-Patent Citations
Referenced by
Original Image


text:
Front desk staff were very polite and check in/out went smoothly.
Air conditioner didn't work on 2nd day of stay. Also, elevator didn't come when button was pushed so had to take the stairs.
Stopped for the night on the way to Miami, great room, nice breakfast.
Absolutely fantastic stay. Location was easily accessable. The staff was very friendly. The entire room was clean. Breakfast was included and provided something for everyone. Will definitely stay here again when traveling back to this area.
Very clean and comfortable!! Would stay here again! Friendly staff! Pool beautiful and clean!!
It was very quiet. The staff was super friendly & knowledgeable.
The room was well represented in the description. Both the service and location were excellent.
The kiddie pool was not cleaned during our stay, and my 2 year old had to play in the big pool.
No restaurant. Not a hotel, an apartment. Worst Sheraton ever.
room was very comfortable-breakfast was well done-staff very friendly
Friendly staff
We enjoyed everything about our stay. We were visiting family in Port St Lucie so we did not have dinner at the hotel but we loved the breakfast menu and appreciated that it was available until 10:30 AM.
just about everything. was very impresserd
breakfast could be improved upon
It was quiet and convenient to our parking space in front of the unit.
No, not really.
I am not there anymore.
Rooms were dirty , sheets missing from bed , dishes were dirty sticking together from food. Breakfast was horrible everything was ran out of, took 30 minutes to some what refill.
good staff... who was cheerful and helpful
I love the cleanliness,food,staff,best we ever stayed in
nothing[phone service not good
Room was clean and had a full size fridge also free breakfast and dinner with beer and wine very nice
Air conditioning unit in our room was extremely loud making it hard to sleep
The Clarion is close to restaurants and the old downtown of Stuart. It was clean quiet and comfortable.
Late arrivals will be limited to opt8on for food or a drink.
None of the above..
The hotel insode bar smelled and the outside tiki was nice but ran out of alcohol.
Staff was very friendly
It was comfortable the clerk were friendly
Had some paint chips in shower
I liked that the hotel was cozy. Being an extended stay hotel, it had the cutest little kitchen area with a stove and oven.
I didn't like that it didn't have a pool.
It was clean, staff was pretty nice
beds were very uncomfortable. hallway was smelly and super hot, breakfast area could have been better like the up keep to it.
The Room and Food, and how clean it was.
No it wasn't.
Our room was right over the front door of the hotel and heard the motor of the door continually open and close all night. Our room window looked out to a wall of the hotel! Terrible experience.
the location to the college where we had a swim meet.
Front desk was rude when checking in to see if they cleaned my room because my child and I highly allergic to smoke. I had called early in week got a very pleasure woman who said they would do extra. Hall just smelled horrible.
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All In, All Pink 2014 Breast Cancer Awareness Event
Posted in Outreach on February 4, 2015 at 12:35 pm
Kelsey Henderson and Shantanu Pradhan from the Lipke Lab represented the Department of Chemical Engineering, Auburn University at the All In, All Pink 2014 Breast Cancer Awareness Event. The significance and message of cancer research conducted in the Lipke Lab was conveyed to the attendees of the event and the public at large.
Abstract accepted for SFB 2015
Posted in Presentations on December 19, 2014 at 2:01 pm
Alex Hodge, Petra Kerscher, Shantanu Pradhan, and Aaron Seeto will be presenting their research in the annual Society for Biomaterials meeting in Charlotte, NC in April 2015.
2014 K-12 Outreach at Georgia Tech
Posted in Outreach on November 17, 2014 at 2:09 pm
Lab Social at Mellow Mushroom
Posted in Lab Socials on April 2, 2014 at 8:36 pm
Presentations at TERMIS 2013
Posted in Uncategorized on November 11, 2013 at 3:31 pm
Lab Social at Mellow Mushroom
Posted in Uncategorized on July 25, 2013 at 9:37 pm
Presentations at BMES 2012
Posted in Presentations on October 27, 2012 at 3:29 pm
Contracting Cardiomyocyte Derived from Human-induced Pluripotent Stem Cells
Posted in Movies, Research on July 25, 2012 at 2:32 pm
Congratulations John and Ben
Posted in Uncategorized on July 15, 2012 at 3:33 pm
Congratulations to John Porter and Ben Spearman for obtaining competitive summer undergraduate research fellowships to support their summer research in our lab! John is creating nanopatterned materials for directing cardiac tissue formation and Ben is researching the role of nitric oxide in cardiogenesis.
Summer REU Student
Posted in Uncategorized on July 15, 2012 at 3:32 pm
We are happy to have summer REU student Kate DeSimone from Brown University working with us this summer!


text:
Picture 2
Picture 3
Picture 4
Picture 5
April Scoreboard
1. BuccinGator - 18
2. kmvenne - 16
3. River_Rat - 12
4. wetookthebait - 9
5. Mr. Mo-Chi - 7
6. CptMasterShake - 6
7. BigBluMasochist - 5
7. ktopp24 - 5
7. D2Moo - 5
8. WarpedMind - 3
9. skinsinsk - 2
9. huachuca - 2
9. Happy4Jets - 2
10. cubufffan - 1
10. jtothed - 1
10. Sportsologist5 - 1
10. perfect91 - 1
10. Meat Supply - 1
It's simple, really. Look at the sports-related pictures above, and give us your funniest caption for any or all of them. You can write as many captions for each as you would like.
The challenge runs daily, Monday-Thursday. Each day's competition will usually be posted by noon ET, and will usually end around 11 p.m. ET. On Monday and Wednesday, Community member ktopp24 will be the judge. On Tuesday and Thursday, I'll run the show. If one of the judges decide that your caption is the funniest or most clever submitted for that picture, it will be declared a winner.
Winning captions will be announced when that day's challenge ends. There will be one winner for each picture, and also one winner for the person who can string together the 5 best captions all with the same theme.
You will be awarded one point for each winning caption that you post. You will see a running tally on the scoreboard, which will be posted at the beginning and end of each day. At the end of each month a champion is declared, and we shower that user in praise and adulation! We add his screenname to the Wall-O-Fame, and then we start everyone's score back at zero.
This is just for fun, and there are no real prizes at this time. Who thinks they can make us laugh? :)


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Quick Roundup
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Linux leaders at open-source summitSubmitted by srlinuxx on Saturday 5th of February 2005 02:57:01 AM Filed under
Here's a long borin^H^Hserious story on how Linux was represented at last weeks open-source summit. I didn't read too much of it, but it might interest you hard core advocates.
Vin Diesel going soft on us?Submitted by srlinuxx on Saturday 5th of February 2005 02:42:23 AM Filed under
Have you seen the previews for Vin Diesels's new movie? He is starring in a soon to be released Walt Disney production co-starring five children! I hope all those tattoos in XXX were stick ons! Well, here's a summary of the flick and here's a shot of the promotional poster. Heck anything with Vin Diesel has got be good!
Doom3 for those with little or no PC!Submitted by srlinuxx on Friday 4th of February 2005 08:04:01 PM Filed under
Here's a story on a board game based on and entitled Doom: The Board Game. This is apparently not breaking news, but I just heard about and got a chuckle over it a few days ago. But hey, I think it might make a neato gift for those diehard doom series lovers, or those who wished they could have played doom3 but couldn't swing the hardware upgrade! Get yours here!
More BS from the Evil One.Submitted by srlinuxx on Friday 4th of February 2005 07:56:15 PM Filed under
Seems Mr. Gates is at it again with saying one thing while trying to cleverly conceal his jabs at Linux. This time speaking of interoperability amongst differing architectures while stating that doesn't mean open source as open source is detrimental to interoperability. Does that seem backwards to anyone else besides me? This is posted all over the net, but here's one reference at Betanews.
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- Systemd 222 Will Do Away With Its Accelerometer
- Linux 4.2-rc1
- Do Your Prefer Modern Or Traditional Linux Desktop Environments?
- illume OS 3 Linux Distro Officially Released, Based on Debian 8.1 "Jessie"
- LibreOffice 5, a foundation for the future
- Samsung Continues to Lessen Android Dependence
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- Benchmarks Of 54 Different Intel/AMD Linux Systems
- Snappy Open House Is Your Chance to Get Familiar with Ubuntu Snappy
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- Ubuntu Touch OTA-5 Will Bring a New Thumbnailer in Unity 8, Support for Refunds
- The July 2015 issue of the PCLinuxOS Magazine
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- KDE Plasma 5.3.2 Lands in Kubuntu 15.10 (Wily Werewolf)
- Intel Has More Graphics Code For Testing, Plans For Linux 4.3


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Is the trolling motor really one of the most important pieces of equipment on your boat? It is when your livelihood depends on it. At MotorGuide, we understand what's most important to our users. It comes down to whether or not your trolling motor performs. It's that simple. Touring professionals are always looking for an edge, and with MotorGuide's Tour Edition, they've found it.Every Tour model combines the Digital advantage with our stainless steel shafts, metal pedals and heads. What is Digital? MotorGuide Digital monitors your motor's amp-draw, heat dissipation, output, and other vital parameters, resulting in a cooler-running, more durable motor with an extended service life. Digital is a self-contained, sealed module in the lower unit that brings all vital motor components together in one protected location, while eliminating outdated analog circuit boards and their related components. Digital allows you to dial into the precise speed you are searching for, and in turn results in longer lasting battery life.Our trolling motors are more than tough, they're virtually indestructible. That's the Tour difference. Only from MotorGuide.**The "Lowrance Inside" Tour Edition nose cone offers standard 200 kHz operation as well as wider, Dual-Search 83 kHz coverage, plus optional high-definition Broadband sonar for optimized sonar and temperature performance. Tour Edition sonar is designed to provide clean, clear signals for the leading brands of sonar such as Lowrance, Eagle, Garmin, and Humminbird. No adapter is needed for Lowrance 7-pin sonar units.Features:Stainless steel shafts and components, metal head, and pedal make this the toughest trolling motor ever.Digital power 75 pounds of thrust with 24 volt.Completely sealed Digital module is protected from heat, moisture, corrosion and shock, greatly improving durability.MotorGuide Digital efficiency results in sustained battery life and more time on the water.Soft-start feature ramps up power, creating smoother initial motion.Quiet, smooth variable-speed operation lets you get closer to the fish.Machete III Prop runs quiet and has a smaller diameter than two-blade designs for the ultimate shallow water performance.Push-pull adjustable steering with stainless steel pulleys is known for its feel and precision, limiting torque and fatigue.Compact, hydrodynamic, lightweight lower units.MicroSwitch is designed to withstand the demands of harsh, wet tournament conditions.Gator Spring Mount features extruded aircraft aluminum for rock-solid durability. A spring return linkage make underwater obstacles a thing of the past.
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Preview: 2015: The Year of Love
We are coming to the end of the year when holiday celebrations overshadow the ongoing realities of war, poverty and violence. For a moment the good cheer (and good spirits) lighten our hearts and dull our worried minds. Life is good when it is celebrated with friends and family at Christmas and, in many ways, this time of celebration nourishes us for the New Year ahead. December 25 is like hitting the pause button on your computer or television and saying – Wow!


text:
Originally from NY. I visit every year.
I am an artist, i really like to paint and draw, mostly on walls, as well as various other crafts and creative outlets.
Embrace decay- create escape.
I am that which must always conquer itself
i have never dressed up like a pirate for Halloween. i do that the other 364 days of the year.
I am not heteronormative. I identify as a straight male but am not in favor of the cut an dry gender binary. In fact, most men piss me off because of the blatant sexist ignorance that goes on when they vomit words. I paint my nails, wear skirts and most of my clothing was found in the woman's section of the thrift store.
"...there's nothing like a lady with a buzz saw..."
for all of you who cant stand bad grammar and upper/lowercase placement... i dont care if theres no plural or "I" isnt capitalized. i hate capitalism (haha and i love puns)
I am a misfit, an outcast, an odd ball and a beard enthusiast...
I drink A LOT of black coffee and prefer RYO cigs and my pipe.
I am DIY, scream FTP, and believe ACAB.
I want to grow old, but never up
Metaphor for life: one can never have too many socks
Witchy survivalist pirate looking for like-minded blasphemes and wingnuts.


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Jammie Lopez's Profile
I am a Mom, Wife, and Photographer! I love arts and crafts, traveling and mint chocolate chip ice cream!! I also love being able to provide other photographers like myself with these beautiful and very durable hand crafted beds! They are great for newborn photography but perfect for toddlers and older children since they can double as a love seat!!
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- Joined December 22, 2010


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Happy family lying on floor after buying new house
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Hours, Location, and Employment Information
Pittsburg Public Library closed for 4th of July Weekend
The Pittsburg Public Library will be closed Friday, July 3rd through Sunday, July 5th.
The library is traditionally closed for the 4th of July holiday. This year, we're closing for the weekend to upgrade software on our library system server.
Have a Safe and Happy 4th of July!
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Are you Verónica Torrano?Claim your profile
Publications (10)64.33 Total impact
- SourceAvailable from: Manuel Rosa-Garrido
Article: Novel CTCF binding at a site in exon1A of BCL6 is associated with active histone marks and a transcriptionally active locus[Show abstract] [Hide abstract]
ABSTRACT: BCL6 is a zinc-finger transcriptional repressor, which is highly expressed in germinal centre B-cells and is essential for germinal centre formation and T-dependent antibody responses. Constitutive BCL6 expression is sufficient to produce lymphomas in mice. Deregulated expression of BCL6 due to chromosomal rearrangements, mutations of a negative autoregulatory site in the BCL6 promoter region and aberrant post-translational modifications have been detected in a number of human lymphomas. Tight lineage and temporal regulation of BCL6 is, therefore, required for normal immunity, and abnormal regulation occurs in lymphomas. CCCTC-binding factor (CTCF) is a multi-functional chromatin regulator, which has recently been shown to bind in a methylation-sensitive manner to sites within the BCL6 first intron. We demonstrate a novel CTCF-binding site in BCL6 exon1A within a potential CpG island, which is unmethylated both in cell lines and in primary lymphoma samples. CTCF binding, which was found in BCL6-expressing cell lines, correlated with the presence of histone variant H2A.Z and active histone marks, suggesting that CTCF induces chromatin modification at a transcriptionally active BCL6 locus. CTCF binding to exon1A was required to maintain BCL6 expression in germinal centre cells by avoiding BCL6-negative autoregulation. Silencing of CTCF in BCL6-expressing cells reduced BCL6 mRNA and protein expression, which is sufficient to induce B-cell terminal differentiation toward plasma cells. Moreover, lack of CTCF binding to exon1A shifts the BCL6 local chromatin from an active to a repressive state. This work demonstrates that, in contexts in which BCL6 is expressed, CTCF binding to BCL6 exon1A associates with epigenetic modifications indicative of transcriptionally open chromatin.Oncogene advance online publication, 23 December 2013; doi:10.1038/onc.2013.535.Oncogene 12/2013; 34(2). DOI:10.1038/onc.2013.535 · 8.56 Impact Factor
Dataset: BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours
- [Show abstract] [Hide abstract]
ABSTRACT: CCCTC binding factor (CTCF) is a highly conserved zinc finger protein, which is involved in chromatin organization, local histone modifications, and RNA polymerase II-mediated gene transcription. CTCF may act by binding tightly to DNA and recruiting other proteins to mediate its various functions in the nucleus. To further explore the role of this essential factor, we used a mass spectrometry-based approach to screen for novel CTCF-interacting partners. Using biotinylated CTCF as bait, we identified upstream binding factor (UBF) and multiple other components of the RNA polymerase I complex as potential CTCF-interacting partners. Interestingly, CTCFL, the testis-specific paralog of CTCF, also binds UBF. The interaction between CTCF(L) and UBF is direct, and requires the zinc finger domain of CTCF(L) and the high mobility group (HMG)-box 1 and dimerization domain of UBF. Because UBF is involved in RNA polymerase I-mediated ribosomal (r)RNA transcription, we analyzed CTCF binding to the rDNA repeat. We found that CTCF bound to a site upstream of the rDNA spacer promoter and preferred non-methylated over methylated rDNA. DNA binding by CTCF in turn stimulated binding of UBF. Absence of CTCF in cultured cells resulted in decreased association of UBF with rDNA and in nucleolar fusion. Furthermore, lack of CTCF led to reduced binding of RNA polymerase I and variant histone H2A.Z near the rDNA spacer promoter, a loss of specific histone modifications, and diminished transcription of non-coding RNA from the spacer promoter. UBF is the first common interaction partner of CTCF and CTCFL, suggesting a role for these proteins in chromatin organization of the rDNA repeats. We propose that CTCF affects RNA polymerase I-mediated events globally by controlling nucleolar number, and locally by regulating chromatin at the rDNA spacer promoter, similar to RNA polymerase II promoters. CTCF may load UBF onto rDNA, thereby forming part of a network that maintains rDNA genes poised for transcription.Epigenetics & Chromatin 11/2010; 3(1):19. DOI:10.1186/1756-8935-3-19 · 4.46 Impact Factor
- EJC Supplements 06/2010; 8(5):178-178. DOI:10.1016/S1359-6349(10)71503-2 · 9.39 Impact Factor
Article: Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest[Show abstract] [Hide abstract]
ABSTRACT: Inhibition of differentiation has been proposed as an important mechanism for Myc-induced tumorigenesis, but the mechanisms involved are unclear. We have established a genetically defined differentiation model in human leukemia K562 cells by conditional expression of the cyclin-dependent kinase (Cdk) inhibitor p27 (inducible by Zn(2+)) and Myc (activatable by 4-hydroxy-tamoxifen). Induction of p27 resulted in erythroid differentiation, accompanied by Cdk inhibition and G(1) arrest. Interestingly, activation of Myc inhibited p27-mediated erythroid differentiation without affecting p27-mediated proliferation arrest. Microarray-based gene expression indicated that, in the presence of p27, Myc blocked the upregulation of several erythroid-cell-specific genes, including NFE2, JUNB, and GATA1 (transcription factors with a pivotal role in erythropoiesis). Moreover, Myc also blocked the upregulation of Mad1, a transcriptional antagonist of Myc that is able to induce erythroid differentiation. Cotransfection experiments demonstrated that Myc-mediated inhibition of differentiation is partly dependent on the repression of Mad1 and GATA1. In conclusion, this model demonstrates that Myc-mediated inhibition of differentiation depends on the regulation of a specific gene program, whereas it is independent of p27-mediated cell cycle arrest. Our results support the hypothesis that differentiation inhibition is an important Myc tumorigenic mechanism that is independent of cell proliferation.Molecular and Cellular Biology 11/2008; 28(24):7286-95. DOI:10.1128/MCB.00752-08 · 5.04 Impact Factor
- EJC Supplements 07/2008; 6(9):123-123. DOI:10.1016/S1359-6349(08)71647-1 · 9.39 Impact Factor
Article: MYC inhibition of p27-induced erythroid differentiation is mediated by the repression of erythroid master genes and uncoupled from its cell cycle promoting activityEJC Supplements 07/2008; 6(9):79-80. DOI:10.1016/S1359-6349(08)71482-4 · 9.39 Impact Factor
Article: The potential of BORIS detected in the leukocytes of breast cancer patients as an early marker of tumorigenesis[Show abstract] [Hide abstract]
ABSTRACT: Brother of the regulator of imprinted sites (BORIS) is a novel member of the cancer-testis antigen gene family. These genes are normally expressed only in spermatocytes but abnormally activated in different malignancies, including breast cancer. The aim of this study was to investigate the expression of BORIS in the leukocytes of breast cancer patients and the correlation between BORIS levels and clinical/pathologic variables. Leukocytes were obtained from whole blood of 87 breast cancer patients and 52 donors not diagnosed with cancer. BORIS protein was detected in leukocytes by immunohistochemical staining; the immunoreactivity score (IRS) of each sample was determined. Additionally, BORIS expression was assessed by Western blot analysis and real-time reverse transcription-PCR. We describe significantly high levels of BORIS (IRS = 4.25 +/- 0.034) in a subpopulation of leukocytes, the neutrophil polymorphonuclear granulocytes, in 88.5% of breast cancer patients. Increased IRS for BORIS in these patients correlated with increased tumor size. In comparison, 19.2% samples from the control group were BORIS positive with only very low levels of BORIS (IRS = 0.25 +/- 0.009). We report here the novel finding of BORIS expression in polymorphonuclear granulocytes of breast cancer patients. This tumor-related occurrence is a phenomenon not observed in donors with injuries and immune and inflammatory diseases. Detection of BORIS in a high proportion of patients with various types of breast tumors indicates that BORIS can be a valuable early blood marker of breast cancer. We conclude that BORIS represents a new class of cancer biomarkers different from those currently used in medical practice.Clinical Cancer Research 11/2006; 12(20 Pt 1):5978-86. DOI:10.1158/1078-0432.CCR-05-2731 · 8.19 Impact Factor
Article: Targeting of CTCF to the nucleolus inhibits nucleolar transcription through a poly(ADP-ribosyl)ation-dependent mechanism[Show abstract] [Hide abstract]
ABSTRACT: Multiple functions have been reported for the transcription factor and candidate tumour suppressor, CTCF. Among others, they include regulation of cell growth, differentiation and apoptosis, enhancer-blocking activity and control of imprinted genes. CTCF is usually localized in the nucleus and its subcellular distribution during the cell cycle is dynamic; CTCF was found associated with mitotic chromosomes and the midbody, suggesting different roles for CTCF at different stages of the cell cycle. Here we report the nucleolar localization of CTCF in several experimental model systems. Translocation of CTCF from nucleoplasm to the nucleolus was observed after differentiation of K562 myeloid cells and induction of apoptosis in MCF7 breast cancer cells. CTCF was also found in the nucleoli in terminally differentiated rat trigeminal ganglion neurons. Thus our data show that nucleolar localization of CTCF is associated with growth arrest. Interestingly, the 180 kDa poly(ADP-ribosyl)ated isoform of CTCF was predominantly found in the nucleoli fractions. By transfecting different CTCF deletion constructs into cell lines of different origin we demonstrate that the central zinc-finger domain of CTCF is the region responsible for nucleolar targeting. Analysis of subnucleolar localization of CTCF revealed that it is distributed homogeneously in both dense fibrillar and granular components of the nucleolus, but is not associated with fibrillar centres. RNA polymerase I transcription and protein synthesis were required to sustain nucleolar localization of CTCF. Notably, the labelling of active transcription sites by in situ run-on assays demonstrated that CTCF inhibits nucleolar transcription through a poly(ADP-ribosyl)ation-dependent mechanism.Journal of Cell Science 06/2006; 119(Pt 9):1746-59. DOI:10.1242/jcs.02890 · 5.33 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: CTCF is a transcription factor and a candidate tumor suppressor that contains a DNA-binding domain composed of 11 zinc fingers. We reported previously that CTCF is differentially regulated during differentiation of human myeloid leukemia cells. In this study we aimed to investigate the role of CTCF in myeloid cell differentiation. A human cell line, K562, that can be chemically induced to differentiate into various hematopoietic lineages was chosen as a model system for this study. Several K562 cell lines with constitutive and conditional expression of CTCF have been generated. By using these model systems we demonstrated that: (i) ectopic expression of CTCF in K562 cells led to growth retardation and promotion of differentiation into the erythroid lineage; (ii) CTCF knock-down significantly inhibited differentiation of K562 cells into erythroid lineage; (iii) differentiation of K562 into the megakaryocytic lineage was not significantly affected; and (iv) down-regulation of MYC has been identified as one of the mechanisms by which CTCF promotes erythroid differentiation. Taken together our results demonstrate that CTCF is involved in the control of myeloid cell growth and differentiation.Journal of Biological Chemistry 08/2005; 280(30):28152-61. DOI:10.1074/jbc.M501481200 · 4.60 Impact Factor
Top Journals
Universidad de Cantabria
Santander, Cantabria, Spain
- Department of Molecular Biology
Hospital Universitario Marques de ValdecillaSantander, Cantabria, Spain


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Branford, CT - United States
Really like the vintage feel you gave to this one!
Rennes, A2 - France
Tied for 2nd Place in 'Who Do We Think We Are' contest :) Many thanks to the people who have been voting for this image !
Tavares, FL - United States
Powerful image, Loriental! VF
Many thanks, Christy ! Your very kind comment and your V/F are much appreciated :)
Whitestone, NY - United States
This isOUTSTANDING....VF
Thank you so much for such a very kind comment and for your V/F, Omar !
Rennes, A2 - France
1st Place in 'LENSBABY images PRIZES' contest :) Many thanks to the people who have been voting for this image !
Tucson, AZ - United States
Beautiful shot and effects, wonderful work Loriental!
Many thanks for such a kind comment, Kume :)
Chandler, AZ - United States
Nice shot of the skyline! v
Thank you so much for your kind comment and vote, Theresa !
Springfield, MA - United States
Beautiful image, Loriental! I love the 'lensbaby' effect!
Thank you very much, Michael ! I am so glad you noticed and liked this one :)
Holbrook, MA - United States
Great retro shot - voted
Thanks a lot for your very kind comment and vote, Alexandra !
Mequon, WI - United States
great vintage look achieved from the vignette and the processing to sepia. vf
Many thanks, Mary ! Your very kind comment and V/F are much appreciated :)
Mena, AR - United States
Excellent work!!
Thank you very much, Nina ! :)
Burnaby, BC - Canada
This is so cool. Love the combo of clarity and blur. Your processing rocks. v/f
Thank you so much for your very kind comment and V/F, Lisa ! I am really glad you do like my processing :)
Columbus, OH - United States
Such an intriguing image! It looks like a picture from yester-year, but the buildings are modern and it has the feel of looking out an airplane window! Really nice mono-chrome vf
Many thanks for your very interesting comment and for your V/F, Karen ! Monochromatic treatment is one of my favorite digital editing tools for creating a certain kind of mood or atmosphere, I am really glad you like the final result in this image :)
Shell Lake, WI - United States
Wonderful effects ....featured "Black Rules" 3/30/13
Thank you so much for your very kind comment and for your feature in Black Rules group ! This is much appreciated, thanks !
Fort Collins, CO - United States
Great processing! v
Many thanks for your kind comment and vote, Julie ! I am really glad you like it :)
Jacksonville, fl - United States
Voted...... We Should Be Ashamed of somethings we do...great presentation. v
Thank you so much for your vote and comment, Sherry ! I intended to create a very dark atmosphere in this image in regards with certain things I have seen when I was living in Hong Kong - despite I do love this city very much.
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The 15 Hottest Female Olympians
Alex Morgan
6 of 16
Sport: Soccer
Country: USA
Sport: Soccer
Country: USA
Plus, a bonus shot of Chris Christie's epic moose knuckle!
Well, we knew it was coming, right? Rumors have been flying for months, nay, YEARS that Ben Affleck and Jennifer Garner were on the verge of splitting, but today — a day after their 10-year wedding anniversary — the couple announced that they're calling it quits for good.
"After much thought and careful consideration,…
Plus, Rihanna adopted a puppy she found wandering around a club bathroom!
Context, folks. It's all about context. …


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Low Class A Stat Wrap
See also: MWL Batting and Pitching Leaders See also: SAL Batting and Pitching Leaders Check out the Triple-A Stat Wrap for a detailed explanation of the methods used here. The […]
See also: MWL Batting and Pitching Leaders See also: SAL Batting and Pitching Leaders Check out the Triple-A Stat Wrap for a detailed explanation of the methods used here. The […]
Aaron Fitt chatted about the New York-Penn League's prospects.
Since we're full off prospect info as we roll out the league top 20s, we're taking Prospect Pulse in a different direction this week. We love the minor leagues, period, and now is as good a time as any to pay homage to Esquire magazine's "Women We Love" feature and put a baseball twist on the long-running feature, giving props to one player in every organization who we can't help but root for.
A rundown of the champions throughout the minor leagues.
Hopefully Minor League Baseball's presidential race will be a spirited affair.
The short-season New York-Penn League was teeming with talent in 2007, and it wasn't limited to the usual group of college draftees making their pro debuts.
The New York-Penn League had more talented teenagers than usual this year.
It's been a little while since I've posted on here–my first Cal League Top 20 list and the birth of my third child has kept me pretty busy–so I thought […]
This week's installment considers all transactions reported between Sept. 15-21. Last week's transactions available here. With the minor league season concluded, most of the transactions center on winter league assignments […]
Ben Badler chatted about the Pioneer League's prospects.
Some polished college talents led the way, but the Pioneer League also had a couple of surprise stars as well.
Great Falls lefthander Aaron Poreda (first round) and Billings shortstop Todd Frazier (supplemental first round) were the highest draft picks to qualify for the Pioneer League list this season, and the two college prospects dominated the Rookie league as expected.
Are underrated homegrown players the key to the Cubs' success? How much of a baseball prospect was West Virginia quarterback Patrick White? How good are recent Dodgers draftees Andrew Lambo and Sergio Pedroza.
The Twins had a second prospect suspended this year for violating MLB's drug of abuse program. Outfielder Eli Tintor was suspended Monday, effective for the first 50 games of the […]
See also: CAL Batting and Pitching leaders See also: CL Batting and Pitching leaders See also: FSL Batting and Pitching leaders Check out the Triple-A Stat Wrap for a detailed […]
Nathan Rode chatted about the Appalachian League's prospects.
To no one's surprise, Danville and Elizabethton dominated the Rookie-level Appalachian League again both on the field and with the prospects list.
Danville and Elizabethton dominated the Appy League and the Appy League top prospects list.
John Manuel answered questions about his Arizona League list.
Dirk discusses calls to the bullpen.


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|Named Person:
|Samuel Chase; John Fries; James Thomson Callender; James Thomson Callender; Samuel Chase; John Fries
|Material Type:
|Internet resource
|Document Type:
|Book, Internet Resource
|All Authors / Contributors:
Samuel Chase; United States. Congress Senate.
|OCLC Number:
|Documents in defence of Judge Samuel Chase, who was charged by the U.S. House of Representatives, and impeached by the Senate, for alleged misdemeanors in the political trials of John Fries and James Callender for treason and seditious libel under the Alien and Sedition Acts.
Imprint from Shaw & Shoemaker, which notes that the Library of Congress copy is "with" its copy of Chase, Samuel. The answer and pleas of Samuel Chase ... Washington City, printed by William Duane and Son, 1805.
Error in paging: p. 35 misnumbered 34.
|Reproduction Notes:
|Electronic text and image data. [Chester, Vt. : Readex, a division of Newsbank, Inc., 2004-2007] Includes files in TIFF, GIF and PDF formats with inclusion of keyword searchable text. (Early American imprints. Second series ; no. 9521).
|54 p. ; 21 cm.
|Series Title:
|Early American imprints., Second series ;, no. 9521.
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Chicago-Style Hot Dogs
Try these Chicago-style dogs for a twist on the classic hot dog.
Level: Easy
Serves: 4
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- 1 tbsp. Grainy mustard
- 2 tsp. white-wine vinegar
- Coarse salt
- ground pepper
- 0.25 sweet onion (such as Vidalia)
- 1 Kirby cucumber
- 1 tomato
- 0.50 c. celery leaves
- 2 tbsp. chopped sport pepper or peperoncini
- 4 beef hot dogs
- 4 hot dog buns
- 4 pickle spears
- Relish
- In a medium bowl, whisk together grainy mustard and white-wine vinegar; season with coarse salt and ground pepper. Add sweet onion, cucumber, tomato, celery leaves, and sport pepper; toss to combine.
- Grill hot dogs over medium-high heat until charred and heated through, 6 to 8 minutes. Serve hot dogs in grilled hot dog buns and top each with a pickle spear and relish.
Looking for more dinner options? Check out our pork chop recipes, chicken recipes, and potato recipes.
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18 Slider Recipes So Good You'll Want One of Each
Pair these mini burgers with a flight of beers and you are SET.
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11 star-shaped things, from pizza to Pop-Tarts. Because are you American or not?
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