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Ratings based on 1,653 Verified Reviews
They paid and stayed. We double-checked.
4.3 Room cleanliness
4.3 Service & staff
4.3 Room comfort
4.1 Hotel condition
They paid and stayed.
We double-checked.
We double-checked.
for Familiesby A verified traveler from San Diego
Great customer service & amenities, okay facility.Posted Jul 2, 2015
Pros: The staff were extremely friendly, the daily resort fee did include a redbox like movie rental system and the room suite we stayed in had a kitchen.
Cons: The outside area & pool could use a revamping.
Location: Sloppy Cakes- highly recommended!
The staff were extremely friendly, cheaper parking fee ($9 day) and great amenities for families such as movie rentals, equipment checkout to play tennis, close proximity to a grocery store. Rooms were spacious and clean.
by A verified traveler from texas
Terrible bedPosted Jun 27, 2015
View was great Staff was great The bed absolutely was awful and so were the pillows Hardly able to sleep- would get up in the morning stiff and back hurting
for Everyoneby A verified traveler
Kaanapali Shores-Posted Jun 26, 2015
Cons: Why charge hotel fee on top of the rate you charge- just add it into the price- this is annoying at many locations these days
The room was very comfortable and the kitchen was great to have and you can walk across the street to Times Market- I travel for business to the outer island this is a great location.
for Everyoneby A verified traveler from Los Angeles
Best location near beach, clean comfort, car mustPosted Jun 20, 2015
Pros: Location, grounds, beach, attitude and attention to the guests. Offering options we guests may not even be aware about.
Cons: To the hotel - just be as good as you are.
Location: Come to the beach at 4am, listen the ocean, do yoga at sunrise, sip coffee at sunset, do jogging, snorkeling, be on/near the water as much as you can.
We (well-travelled couple) were exceptionally pleased by the hotel complex, grounds, service, cleanness, friendliness, and were fortunate with the weather (June 13-19). We did not ask but were offered an upgrade from a standard room to a studio with kitchen (what a difference it made!), did not asked but offered a complimentary hospitality suite for one hour to refresh ourselves with shower at 6 pm before heading to the airport. The hotel staff was welcoming and made us feel living in comfort. We explored island by all main routes - Aston Kaanapali Shores was definitely our lucky choice: long stretch of sandy beach; 4 ml to a tourist hub Lahaina (enjoyable to visit, to take an ocean tours but not to stay); about 4 ml to the north you will find a nice, semi-secluded sandy beach where on an occasion you may meet a celebrity (our apology to those who might be displeased by this disclosure); 45 min drive to Costo; not as windy as you may find out in Makena State Park beach; and, of course, the road to Hana (not Hana itself, about 3-1/2 – 4 hours drive one way) is incomparable – first time we saw the rain forest "eating" into a narrow serpentine road with picturesque one-car bridges (roller coasting is not advised). Enjoy it !!
for Everyoneby A verified traveler from Nebraska
Enjoyed our time herePosted Jun 19, 2015
Pros: It is very pretty and the staff was very helpful.
Cons: Maybe put locations of laundry facilities in the welcome book (book says to call housekeeping).
Location: Near pretty much everything. Maui is a small island and very easy to get around.
Staff was very friendly, rooms were very nice. We did have to call one day because our room was missed by the cleaning team (or they were very late). The room was never vacumned in the week that we were there, and as we called one day to have someone come up to clean the room, we didn't bother to call again. The floor got a bit sandy from the beach! Other than that, our stay was very nice! I would go there again.
by A verified traveler from slidell, la
Posted Jun 16, 2015
Pros: nothing
Cons: the staff can be more friendly, nicer and helpful.
Location: you have to rent a car because everything is extra and have to drive there.
ac was at 78 degree that is with a fan in the room. moss and flea bite all over ours body. Told the front desk but nothing was done. lucky for us we're only there for 2night. nightmare
for Everyoneby A verified traveler from Ogden,Utah
Relaxing and close to beach.Posted May 30, 2015
Pros: Room was very comfortable and close to markets and restaurants and a wonderful view of ocean. Restaurant staff was very kind and nice.
Cons: check in and out times could be more flex able and more additions to the dinner menu.
Location: Basic needs are close by but if you would like tours and attractions you will need transportation and funds.
Close to the beach very relaxing environment and good food at hotel and elsewhere.
for Everyoneby A verified traveler from seattle wa
Enjoying the simple thingsPosted May 19, 2015
Pros: Unlimited free movie rentals from the hotel kiosk. Friendly staff, layout of building, garage parking.
Cons: There are 3 BBQ's wedged between tennis courts and parking garage. Not exactly a great venue to gather and enjoy a meal.
Location: A car is a must. Drive south 5-10 m to Whalers village for the best beach around at Kaannapali. Lahaina is close. Kappalua ocean trail is north.
A great intimate atmosphere with a more relaxed and friendly vibe than the big resorts with all their bells and whistles. Guests are friendlier, more engaging and seem to just be happy to be on vacation. Anchored by a garden pool between both buildings, all rooms are positioned for some type of water view. We were expecting to face inland. The only downside is a narrow beach that catches lots of wind at all times while we were there. A short walk south and you come to other beaches that seem to have a little more shelter. If you're a runner, there is a great 5k run south toward Black Rock.
for Everyoneby A verified traveler from Arizona
Great hotel with ocean views and beautiful groundsPosted May 18, 2015
Pros: Great view, pool and restaurant. Easy drive to all and loved that there was grocery store within walking distance.
Cons: Would have liked the coffee hut open. But understand that it is a slow time.
Location: Zip lining was the best.
Needed a two bedroom room/condo for my adult son and I as we were attending my niece's wedding. Perfect choice. The grounds were immaculate and made for nice walking in the morning. Hotel stores carried just about everything. Staff at the restaurant were exceptionally nice and service was terrific.
by A verified traveler from m
Dated facilitiesPosted Apr 28, 2015
Rooms were very dated, old carpets, furniture, lighting. Had repainted and updated kitchen and bath partially. Online pics are not current, they have no real usable beach left after erosion. Business area for printing boarding passes, internet use was closed, "under renovation", yet saw no work being done in 10 days we were there.


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On paper, the publisher of such top-selling franchises including Finding Nemo, Full Spectrum Warrior, and Tak reported numbers that paled when compared with those of the same quarter a year ago. For the company's second quarter of fiscal year 2005, which ended September 30, 2004, revenues were off 23 percent compared to last year; and instead of reporting a profit as it did for the same quarter in its FY04, the company lost money.
Investors, however, rewarded the company in after-hours trading, pushing its share price up. Why? Apparently, Wall Street sees value in THQ's future--enough so to forgive its currently lackluster finances. For the quarter, the company reported net sales of $96.3 million and a net loss of $6.4 million. But those superficially bad numbers actually beat THQ's expected revenues for the quarter by almost $15 million.
For the current October-December quarter, the company says it expects to drive $330 million in revenue, up 13 percent from last year's holiday quarter. CFO Edward Zinser said it expects three titles to sell over a million units during the quarter: The Incredibles (based on the Pixar film), The SpongeBob SquarePants Movie, and Tak 2. More dramatically, Zinser said he expects THQ to also outperform the previous year's January-March quarter. In today's conference call, Zinser said the company expects to realize revenues of $165 million in the Jan-Mar '05 quarter, a year-on-year increase of 34 percent.
Zinser said THQ was in the process of shipping 2.5 million copies of The Incredibles into the worldwide retail channel, 1.2 million copies of The SpongeBob SquarePants Movie, and next week, the company will ship 1.5 million copies of the latest of its popular wrestling games, WWE SmackDown! vs. Raw.
In 2005, THQ is looking for strong sales from The Punisher in January, MX vs. ATV Unleashed in either February or March, Full Spectrum Warrior for the PS2 in March, and Destroy all Humans! for Xbox and PS2 in April, according to Zinser.
Also on the positive side, THQ stated that its THQ Wireless division is expected to contribute more than $20 million of THQ's net sales in fiscal 2005, three times what it contributed a year ago. Costs associated with developing its wireless gaming business are expected to climb, but the company is confident that the mobile entertainment sector holds substantial potential.
President and CEO Brian Farrell tempted listeners with the news that THQ has bought Southern California-based studio Concrete Games. The new studio--THQ's ninth internal developer--is expected to contribute both creative content and next-gen technology. However, when asked to elaborate on the purchase, Farrell declined, saying now was not the time to get into specifics. "When we want to get more aggressive with announcements, you'll know why we're not talking much about the company at this moment."

subset: commoncrawl


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Thanks for repeating all the usual stuff that we've read on all the other sites for years, yeah. It's always good to be reminded isn't it?
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VIEWS: 76 PAGES: 13 CATEGORY: Humanities POSTED ON: 4/14/2011 Public Domain
Bouncy rhyming couplets describe five ducklings and their bicycle expedition to an apple tree: "Wind-swept ducklings coast to a stop / At a rock by a tree with a snack on top." Three brief rhyming stories about a rambunctious pig feature preschooler-centric subject matter such as messy eating and costume changes for different activities: "When he wears his yellow coat, / Piggy Pie Po likes to boat." Exuberant acrylic paintings of Piggy in action set against lots of white space match the text's jaunty energy, cmh Yolen, Jane Hush, Little Horste 32 pp.
4 • PRESCHOOL July–December 2010 The HORN BOOK GUIDE PRESCHOOL ▲ Berger, Samantha Martha Doesn't Share! 40 pp. Little ISBN 978-0-316-07367-7 $16.99 Alborough, Jez The Gobble Gobble Moooooo Tractor (2) Illustrated by Bruce Whatley. Little otter Martha does- n't like to share. But when her parents and baby brother Book
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Acadia Harbors and Heights
Why not begin your journey of Maine with a majestic tour of the coastline? Many locations including ranging from Acadia National Park, to Bass Harbor Lighthouse offer exquisite opportunities to capture the beauty in our glorious state.
Nestled at the confluence of the Penobscot River and Penobscot Bay, the town of Bucksport depicts a progressive coastal town offering unique amenities that include sightseeing, fishing, exploring historic sites, a historic movie theatre, and much more.
Maples and Mountains
Beginning on Route 11 in Naples, and ending on Route 302 in Bridgton, allow Maine to bring you on a journey through its mountains and lakes
The Spark Plug
Last week we enjoyed a lighthouse tour. Pharologist Ted Panayatoff was in great storytelling form and we had a chance to get up close and personal...
Windjammers and Water Views
Following Maine's historic coast are a series of water views and opportunities that will take your breath away
Bailey Island Bridge
For many years, the fishermen who lived on Bailey Island wanted a bridge to connect their island with Orr's Island. For many years, the town of Harpswell turned down the request.
Covered Bridges
Between the mid 1800s and early 1900s, covered bridges began to appear over Maine's mighty rivers allowing travelers in horsedrawn carriages to forge rivers without getting swept downstream.
Penobscot Narrows Bridge and Observatory
A one-minute elevator ride will take you to one of the most unusual views in Maine, a 360 degree view from 437 feet above the Penobscot River, just a few miles up river from Penobscot Bay.


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From Coal's site: "Welcome to Coal Considered, a classically-inspired collection of headwearwhere no detail is overlooked. From the finest materials toinnovative designs never seen before, the Considered collectionis as unique as you and the lifestyle you live"


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Can Skoda's new Superb take the family and fleet car crown from VW?
Skoda's flagship Superb ditches the old car's awkward looks for sleek styling, plenty of space and value for money
How does the super-spacious Skoda Superb Estate stack up in 2.0-litre TDI guise?
Featured in: Auto Express New Car Awards 2015: the winners
The Skoda Citigo is the 2015 Auto Express City Car of the Year, with the Hyundai i10 and Renault Twingo commended
The Skoda Superb is the 2015 Auto Express Family Car of the Year, with the Mazda 6 and Volkswagen Passat commended
Latest spy shots show Skoda's new seven-seat SUV testing ahead of late 2016 arrival
Skoda's new Superb load-lugger will be available to order in June with likely £19,850 starting price
Skoda has knocked up to £1,905 off the prices for its Rapid Spaceback family car
The Skoda Superb 4x4 is a full-blooded V6 petrol flagship that makes a great performance car
Skoda has released sketches of a booted rally car concept that wiill be unveiled at Worthersee GTI Meeting
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Bijapur to Mumbai distance is approximately 640Kms by road. With a total of 3, redBus offers options to choose from 2 operators for Bijapur to Mumbai route. VRL Travels, Jts Travels operates the maximum number of services from Bijapur to Mumbai route. Bijapur to Mumbai bus timings vary with different operator, it takes around 10hrs to 11hrs to complete this journey depending on the operator, type of bus and traffic conditions. Buses from Bijapur to Mumbai are available from 08:00 PM to 09:30 PM. Bijapur to Mumbai bus fare ranges from Rs.660 to Rs.1000 depending on the type of bus.
Travelling from Bijapur to Mumbai can be comfortable and easy as there are many types of buses available for travellers. Different type of buses are available in this route like A/C Sleeper, Non A/C Seater. Now that redbus has tied up with many operators, booking tickets from Bijapur to Mumbai has become very easy.
Mumbai, earlier known as Bombay, is the capital of the State of Maharashtra. Since most of the countries big financial institutions (like RBI, Stock Exchange and so on) is located it Mumbai, it is also considered as the financial capital of India. Mumbai is one of the most crowded cities of the country as well as the world. It ranks fifth in the list of the most densely populated cities of the world. Nonetheless, Mumbai welcomes people from all walks of life irrespective of their backgrounds. The British developed what was a cluster of seven islands into the bustling city called Mumbai. It was also under the British rule that the place attained importance and further developed into a major financial and commercial hub of the country. Now, Mumbai is often called the City that never sleeps, owing to the commercial and financial activities that the city witnesses even during the night times.
The journy was very good and comfortable.
Fixed Pilllows were uncomfortable.
Bus can be made better - with better suspension as in Volvo.
Bus condition is very bad..its horrible to make travelling


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Originally written on BlackSportsOnline | Last updated 4/15/13
According to Adrian Wojnarowski of Yahoo Sports, Georgetown sophomore Otto Porter Jr. is the most recent college player to declare for the 2013 NBA Draft. Georgetown All-American Otto Porter Jr. will enter the NBA draft, a source told Yahoo! Sports. Porter, a first-team consensus All-American and the Big East Player of the Year, will make his decision public at a news conference Monday on campus. Porter averaged 16.2 points and 7.5 rebounds for the Hoyas this season. Draftexpress.com rates Porter as the eighth-best prospect in the 2013 draft class. At 6-foot-8, Porter has rapidly improved from a solid college recruit to a lottery pick.
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From $1,625 / week
Description from the manager
Description from the manager
Bedrooms: 4/
Bathrooms: 3/
Sleeps: 10/
Type: House
This spacious sound front home is nicely situated in a private location, and a waterman's delight with unobstructed views of the Pamlico Sound from all levels. In addition, and just steps from the door, is convenient on-site water access (great for wading, crabbing, kiteboarding, windsurfing, kayaking and other portable watercraft), where these shallow sound waters offer adventure and fun for all ages.The concrete drive and carport area provide parking and space to stow your gear. The entry just off the carport opens to the ground level hallway with a storage closet and stairs leading up to the second level, which has three bedrooms, a game room...Read more
About the manager
About the manager
Midgett Realty
Midgett Realty
- Response rate: n/a
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- Calendar updated: today
Overall rating:
3.9 / 5.0
SAIL STATION Buxton, North Carolina
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CasementsJune 15, 2014Park • Ormond Beach, United States
A beautiful scenic place
Photographer.......checking in
Awesome establishment to relax converse and enjoy cigars for the aficionados!
Don't half step get the blsck card. Its worth it!
Brain freeze? Place the underside of your tongue on the roof of your mouth! I almost lost it in traffix lol
A little snippy at counter....drive thru is ok
Great atmosphere...tasty breakfast sandwhich..wifi and friendly owners
Take this mayorship I spent my bucks at International Academy. Slow response and run arounds lack of vet info
Self Checkout rocks! No clerks with attitudes...I may be back!
Its a shame to make a veteran wait so long in the e.r . A disgrace.
Go see Robert in meats he is a great guy giving me tips for 5 years!
Remember there is only one goal....Finish on time and ignore drama. Rise above and be the star that you were meant to be
Rude customer service reps...all the time....last visit.
Love place! Excellent merchandise! Im in the process of gathering images from past shoots where models are wearing wardrobe from goodwill....smiling....they will line the walls of the store :-) wow!
Very rude and will ignore customers even though they are in line. Fair is fair.
The place to be if you are I to chakras...feng shui...earthy living...naturalist..consciousness etc...
New rewards card is so convenient! No dragging the paper around! Lol


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Using tracer viruses, researche... Read More
For decades, scientists have known that deforestation is one of the greatest threats to the biodiversity of the Amazon rainforest, which has the highest number of plant and animal species of any region its size on the planet. Now, scientists have found out that deforestation is a threat to the d... Read More
Hydraulic fracturing, or "fracking", is the process of drilling and injecting fluid into the ground at a high pressure in order to fracture shale rocks to release natural gas inside. What effect does this process have on the microorganisms that naturally exist in the water in this process?
... Read More
In this post from my microbiology/education blog, I discuss a post on Boing Boing recently that used a video I had made of ice nucleation bacteria. Ice nucleation bacteria are very interesting of course, and I link to the Boing Boing post. In addition, I provide an additional video of students... Read More
Feeling lonely! Just remember you are not alone. A huge number of bacteria live in your body, and most of them are in your intestine. But you do not need to be worried about it, because they will not hurt you in a normal situation. In fact, the relation between humans and their microbiota is an... Read More
Dr. John Spencer is a mycobacteriologist studying leprosy at Colorado State University. He has collaborators in the northern state of Para, Brazil, who visit schoolchildren in about 10 different cities in the Amazon region and elsewhere to diagnose and treat kids and family members who have t... Read More
Trypanosome Lytic Factor (TLF) has emerged as a novel arm of innate immunity that is only present in humans and select non-human primates. TLF was originally discovered in human blood as a minor form of High-density lipoprotein (HDL), also known as a good cholesterol, that rapidly kills the Afri... Read More
Should we only consider bacteria as harmful to our bodies?
Bonnie Bassler is a molecular biologist who has made a stunning discovery: bacteria 'talk' to each other using chemical signals that enable them to act as a unit, mount attacks and coordinate defence. This phenomenon of bacterial com... Read More
The disruption of the human microbiome through use of antimicrobials is a topic of growing interest among healthcare epidemiologists, not only because it is a major risk factor for C. difficile infection (CDI), but also because it could be a driving force behind the introduction and proliferatio... Read More
Almost 1 out of every 3 people in the United States will develop shingles during their lifetime. Despite the approval and recommendation by the FDA of a shingles vaccine for adults over 50, only 16% of American seniors over 60 are vaccinated. Vaccinations are even lower for those aged 50-60. A... Read More
Water Lecture Series
John Mekalanos discusses the biology of cholera, driven by his investigations on the molecular genetics of the causative bacterial organism. With his many colleagues in Bangladesh, Haiti, and elsewhere, he has provided strong evidence for how this organism emerged as a hu... Read More
Plants associated bacteria play a key role in host productivity and health. These bacteria are phylogenetically diverse and form interactions considered neutral, beneficial or detrimental. A better understanding of these interactions will have a direct impact in agriculture by promoting sustaina... Read More
During the April 2013 avian influenza A (H7N9) outbreak, more than 130 human infections with H7N9 were reported. Most patients had severe respiratory illness and 44 people have died. Studies suggest that the H7N9 virus has developed resistance to oseltamivir. A human interferon already in use fo... Read More
The Rockefeller University's Luciano Marraffini is interested in understanding how bacteria evolve by incorporating DNA sequences from other bacteria or from the environment into their genomes. His research focuses on the mechanisms that control the traffic of DNA molecules between bacteria.
Read More
A quick demonstration of how my Microbial Mania can impact the holiday season! Read More
Many air travelers are concerned about the risks of catching a disease from other passengers given the long time spent in crowded air cabins. New research shows disease-causing bacteria can linger on surfaces commonly found in airplane cabins for days, even up to a week. Participants discuss ... Read More
The emergence of human infections with avian influenza viruses (H7N9 and H5N1) have raised concerns about the virus gaining the ability to spread person-to-person, potentially causing a deadly pandemic. So far the number of human cases has been limited but the mortality rates have been high. ... Read More
An Ebola outbreak has killed at least 59 people in Guinea, UNICEF said, as the deadly hemorrhagic fever has quickly spread from southern communities in the West African nation.
Experts in the country had been unable to identify the disease, whose symptoms -- diarrhea, vomiting and fever -- we... Read More
ASM Global Video Challenge submission!
Hello ASM! I am a microbiology graduate student in the Runstadler Lab at MIT. We are an interdisciplinary group of scientists comprising biochemists, ecologists, computer scientists, veterinarians, and microbiologists. Together, our lab studies all aspec... Read More


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$10 off $75 Home, Sports, School Supplies, Fashion, & Beauty - Back to School. Use promo code BACK2SCHOOL at checkout. Ends 7/8/2015.
Learn more about Hot/Cold Foot Shiatsu:
Manufacturer: Helen of Troy
Mfg Part#: DRMA7802
Sku: 211423712
See more in Massagers
|The first hot and cold foot massager in the industry. Multiple settings.Select shiatsu massage or shiatsu massage with heat or cooling feature.Shiatsu massaging nodes for deep muscle relief.Delivers hot and cold therapy to feet.Warming shiatsu massage treats sore achy feet.Cooling shiatsu massage refreshes and re-energizes tired feet.Touch toe buttons easy to use with a press of a finger or a toe. Hot and cold foot massager. Multiple settings. Shiatsu massaging nodes. Delivers hot and cold therapy to feet. Warming shiatsu massage. Cooling shiatsu massage. Product: 4.50 W x 11.38 H x 13.75 L.


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- M.F.K. Fisher born (1908)
Your Starbucks Grande Cup of Coffee Has More Caffeine Than Your Energy Drink
Today on The Daily Meal
Recipe of the day
Most Recent
- A Perfected Kombucha Beer, the 'Healthy Alcohol' Will Soon Hit the Mass Market
- Brooklyn Artist Sues Starbucks for Alleged Copyright Infringement
- La Colombe Creates First-Ever Latte on Tap
- Starbucks Has Lined Up 6 New Frappuccino Flavors, Including Cotton Candy and Cupcake
- Starbucks Has Taken the Classic Cappuccino Off the Menu at Many Locations
Um, should we be possibly worried the next time we hit Starbucks for our 3 p.m. jolt of energy? Despite the newest research that proves a connection between happiness and coffee, a new study published by the American Chemical Society shows that your grande cup of coffee can pack a near-dangerous amount of caffeine.
While the talk of caffeine and safety has mostly centered around energy drinks (including those death reports linked to Monster Energy Drinks and 5-Hour Energy), it seems that the conversation has ignored the coffee giants of America. And according to the American Chemical Society's study, a grande cup of coffee from Starbucks has 330 milligrams of caffeine — in comparison, a 5-Hour Energy drink has 215 milligrams of caffeine. And the amount of caffeine most people agree upon to be safe is just a tad higher at 400 milligrams per day. (However, as the study points out, the FDA hasn't officially declared a ruling on how much caffeine is safe.)
However, Starbucks has spoken out against the study, and was quoted by the Daily Mail as saying that the chain's grande size only contains 160 milligrams of caffeine. (Business Insider also notes past studies that show Starbucks' coffee contains more caffeine than Dunkin' Donuts' coffee.) And of course, there's one big caveat to all the hoopla; as the scientists note, everyone reacts differently to caffeine. Says the study:
"Fifty percent of the caffeine a person takes in gets cleared from the body, on average, in five hours. But studies have shown this rate can vary because of other drug use: Women taking oral contraceptives break down caffeine slower than those not on a contraceptive pill, and people who smoke process the stimulant faster than those who don't. Genetics also plays a big role in how a person reacts to caffeine. For example, men metabolize caffeine faster than women."
But if our Starbucks may also make us as jittery as an energy drink... what are we supposed to do to get through the work day?
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Bruce Springsteen Crashes David Geffen's Documentary Premiere
The Boss was a walk-in at the mogul's star-studded Nov. 13 event, featuring Cher, Tom Hanks, Steven Spielberg and Warren Beatty.
This story first appeared in the Nov. 30 issue of The Hollywood Reporter magazine.
It's clear that David Geffen's the boss from the PBS American Masters documentary Inventing David Geffen: The man invented modern moguldom.
PHOTOS: 20 Biggest Political Players in Hollywood
But at the L.A. premiere Nov. 13 at the Writers Guild Theater, hosted by Cher, Tom Hanks, Rita Wilson, Steven Spielberg, Kate Capshaw, Warren Beatty and Annette Bening, there was another boss present: Bruce Springsteen.
Organizers tell THR he was "a walk-in." When a well-wisher congratulated him on helping to re-elect President Obama, Springsteen actually blushed.
"I only had a little, little bit to do with it," he tells THR.
STORY: 'Inventing David Geffen' Draws Rare A-Plus Crowd to L.A. Premiere
Meanwhile, at a Spago dinner afterward, some feelings were hurt when organizers apparently kept some of Geffen's pals off the list.
Geffen himself arrived with date Oprah Winfrey and claimed to have nothing to do with the dinner guest list.
Never miss a story. Stay up-to-date with THR's Daily Headlines.
Must Reads
Hollywood Insiders Descend on Havana
CBS Entertainment Chief and "Loudmouthed Feminist" Nina Tassler Reveals the Strategy Behind 'Supergirl' Gamble
Paul Rudd and Marvel's Kevin Feige Reveal 'Ant-Man's' Saga, from Director Shuffle to Screenplay Surgery to Studio's "Phase Three" Plans
Comic-Con 2015: THR's Full Guide to Parties in San Diego
HBO's Real-Life Game of Thrones: The Fight to Stay Rich, on Top and Score Bill Simmons
Taraji P. Henson, Viola Davis and Drama Actress A-List Tackle Race, Sexism, Aging in Hollywood
Lena Dunham, Amy Schumer and Comedy Actress A-List in Raunchy, R-Rated Roundtable
Bob Odenkirk, David Oyelowo and Drama Actor A-List on Oscar Snubs, Bad Scripts and Getting Ignored by Robert Redford


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Qualcomm Photobooth pairs 130 HTC One smartphones for 540 degree view GIFs
Qualcomm has created something called the "Ultimate Photobooth" which is able to capture 540 degree GIFs. This setup makes use of 130 HTC One smartphones and is designed to show off the power of the Qualcomm Snapdragon processor. In the case of the HTC One, that would be a quad-core 1.7GHz Snapdragon 600 processor.


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Includes 1.59 Index Single Vision Lenses
These Bulova Dijon Amethyst Gradient eyeglasses are a funky Kool-Aid purple with caramel brown highlights. The frame is a characteristic oval shape with an accented temple for a subtle cateye feel. The arms feature a pretty floral stencil imprint with jewel accents for a little bit of sparkle.About the Brand
Bulova has been designing top quality products since 1875 and has forged a legacy through creativity and excellence. Using only the highest quality materials, Bulova eyeglasses are stylish, modern, and always a top pick amongst the fashion-forward.


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|Reviews for The Lady's War and the Gentleman's Engagement
| gginsc chapter 102 . 1/4
The hell it will! What an ass! Why is Guthwyn so spineless?
| ZabuzasGirl chapter 102 . 1/3
...I'm gonna kill Thranduil!
Here's an idea have someone know of their conversation and tell Legolas. The confrontation between him and his Father should be interesting.
Update immediately, please!
| Guest chapter 101 . 12/20/2014
I love this so much, your imagery and understanding of the language and culture they have is so good but I'm having a hard time picturing what gúthwyn looks like
| Kiiimberly chapter 101 . 12/18/2014
Thanks for updating anolinde. Really enjoyed this. Hope she's not feeling too jealous.
| Guest chapter 101 . 12/18/2014
I finally managed to catch up with this story, can't wait until the next chapter, one of my favourites by far
| Ysmira chapter 101 . 12/15/2014
Yeah Ive finally reached this chapter! :) It was great, especially the second part. Tauriel, and Elfwine learning Elvish and Elves singing in the night (I could almost hear them). But I hope Guthwyn will soon realize what she is feeling, cause her attraction lasts long enough, and maybe its time for some plot twist? :)
I must also say that Ive never really liked Legolas ( at least not as much as Aragon, Galadriel, any Maiar or badass elves from First Age or Second), especially in fanfics. It may be because all those Legoromances lurking here and there. :) But your Legolas is totally different, he has some "core" and he is really living here, and I really like him and even admire his PoVs. :)
| Doll-Fin-Chick chapter 101 . 12/14/2014
Elfwine really lives up to his name :3
Awww Guthwyn is jealous. I wonder how you're going to spin this with Tauriel, she had a thing for Legolas in the movies, wonder if it's still there?
| gginsc chapter 101 . 12/14/2014
Guthwyn, Guthwyn, You really need to get a clue! Love Elfwine in this chapter. He is so adorable!
| Midknight911 chapter 101 . 12/13/2014
Aww! Super adorable! I adore Elfwine for his ability to accept things others find difficult and for how wise he is. Tauriel, . I just love her! And she really is similar to Gúthwyn personality-wise. Oh this is definately starting to move along again and I cant wait for the next chapter.
| ZabuzasGirl chapter 101 . 12/13/2014
awwwwwwwwwwwwwwwwwwww. so cute!
maybe have thranduil talk to her again in the next chapter
Update immediately, please!
| Kiiimberly chapter 100 . 11/27/2014
Thanks for the update anolinde. I'm looking forward to the next one! :)
| Midknight911 chapter 100 . 11/24/2014
I love how you showed some of Gúthwyn's strength in this chapter. Lately it's been sort of nonexistent, which I am not complaining about but I missed it. Oh boy is legolas in trouble, I think he finally realizes that almost everyone except him and Gúthwyn knows what's goon on. Man but I didn't see much jealousy on Legolas' part when she was with the men sadly, I was kinds looking foward to that. Oooh I wish some Elfwine or Cobryn wisdom will be headed our way. Cant wait for your next amazing chapter.
| Brynhilda chapter 100 . 11/24/2014
Haha, this is just priceless.
Not only Legolas is tongue-tied, but Thranduil and his advisor are starting to cower, seeing Guthwyn as a immediate and lethal threat to their beloved heir.
I love your depicting of Guthwyn's thoughts and emotions in this chapter. _
Well, now that the hobbits, dwarves, humans and royal Elves are all enjoying the night, may Cobryn also meet Tauriel ? Even if it's just so that they can gossip together about Guthwyn and Legolas. Pretty please ! ;-)
Does anyone has the recipe of the Beornings' honey cakes, by the way ?
| Doll-Fin-Chick chapter 100 . 11/24/2014
Oh my god. Legolas tongue-tied! And Guthwyn being more observant than usual. -gasp-
Sexy hair is sexy and Legolas totally gave himself completely away at that point haha
I love all the details and the attention you pay to canon. It's amazing how your story is just as immersive as the original :)
| funnygirl00 chapter 100 . 11/23/2014
Oh, drat it! Things were going so well. Now, I've got to wait for that next chapter! I hope that Guthwyn allows Legolas to have that dance after that moment.


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Watch Resurrection Season 1 Episode 4 online to see what happens after Jacob suffers a seizure.
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When Jacob suffers a seizure, Maggie gets surprising results from his physical on Resurrection.
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2007 Toyota FJ Cruiser Q&A
2007 Toyota FJ Cruiser Question: When I put my car into 4WD the "VSC Trac off" light came on.
What does this mean? Can I take it anywhere or should I go to a Toyota dealership? - susan k
Answer 1
you should check the book in the glove box first, its tells you about those light and what they mean, from what I read when putting the car in 4x4 the vsc is turn off, this is ok vsc stand for Vehicle Stability Control Thanks Bills On Broadway - Bills On Broadway
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Buy My Novels!
My novels are available for purchase right now! This is getting a bit too unwieldy to keep updating each time a new novel comes out. And why go to all that trouble when I have a store on my website that does it all for me? So check it out! You'll find everything I've written (and stuff other people have written) over there. :D If you'd rather buy from a smaller company that offers more than just Kindle copies, Smashwords is dandy!
My Amazon Store
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My Smashwords Author Page
And after you buy, pimp me! :D


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Say goodbye to these 62 titles leaving Netflix in March
Get in those free viewings of "The Graduate," "Air Bud" and "Anaconda" while you still have the chance!Wednesday, Feb 25, 2015 10:15 AM UTC 0
Entertainment the daily dot, Netflix
Get in those free viewings of "The Graduate," "Air Bud" and "Anaconda" while you still have the chance!Wednesday, Feb 25, 2015 10:15 AM UTC 0
The comedy website released its second viral Obamacare video on Tuesday. Here's why VIDEOThursday, Mar 27, 2014 1:02 PM UTC 0
In recent years, the "Charmed" and "Who's the Boss?" actress has become a staunch defender of Internet freedomsThursday, Jan 23, 2014 12:50 PM UTC 0
Get ready to feel really, really old VIDEOSaturday, Jan 11, 2014 8:00 PM UTC 0
The new law -- part of a bigger Sexual Harassment Prevention Bill -- was passed to combat "virtual rape"Thursday, Jan 9, 2014 1:30 PM UTC 0
A revealing new survey suggests it's harder than you might thinkSunday, Dec 8, 2013 6:00 PM UTC 0
Child stars Mike Maronna and Danny Tamberelli on mid-90s Nickelodeon, and their newest reunionTuesday, Oct 22, 2013 12:45 PM UTC 0
Forget "binders full of women." This year it's all about the Internet's most insufferable couple VIDEOSunday, Oct 6, 2013 9:30 PM UTC 0
"I feel dizzy," the young boy says to his mother, who's filming. "Why do I feel dizaaaaay?" VIDEOSaturday, Sep 28, 2013 12:30 PM UTC 0
Recently he'd been documenting his health troubles caused by a brain tumorFriday, Sep 20, 2013 12:58 PM UTC 0
Ten University of Vermont students allegedly sought an older woman to cook them meals in exchange for "hot sex"Thursday, Sep 5, 2013 12:30 PM UTC 0
Classifieds advertise tests for women hoping to trick their boyfriends into popping the questionSaturday, Aug 31, 2013 1:00 PM UTC 0
Beware of clicking links to "exclusive" first photos or "secret" video of the heir-to-be, security experts warn VIDEOMonday, Jul 22, 2013 8:22 PM UTC 0


text: So much better than a chain hotel. Cool old historical house that lets you bring your pet(s). We brought our 2 dogs and felt very welcome. The Ruby room has a kingsize bed that was fabulous. Never slept so well on a bed away from home especially on the first night. Owners werent there the first night so a very... More


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Natalia comes around after a bit of ruminating to sappy music.
In this day and age, this is probably the best we can hope for … until the next Kendrick comes around.
I love that Matt Lauer has an arc in our movie where he comes around and accepts the word 'sharknado,' and then kills a shark.
Old English cuman "come, approach, land; come to oneself, recover; arrive; assemble" (class IV strong verb; past tense cuom, com, past participle cumen), from Proto-Germanic *kwem- (cf. Old Saxon cuman, Old Frisian kuma, Middle Dutch comen, Dutch komen, Old High German queman, German kommen, Old Norse koma, Gothic qiman), from PIE root *gwa-, *gwem- "to go, come" (cf. Sanskrit gamati "he goes," Avestan jamaiti "goes," Tocharian kakmu "come," Lithuanian gemu "to be born," Greek bainein "to go, walk, step," Latin venire "to come").
The substitution of Middle English -o- for Old English -u- before -m-, -n-, or -r- was a scribal habit before minims to avoid misreading the letters in the old style handwriting, which jammed letters. The practice similarly transformed some, monk, tongue, worm. Modern past tense form came is Middle English, probably from Old Norse kvam, replacing Old English cuom.
Remarkably productive with prepositions (NTC's "Dictionary of Phrasal Verbs" lists 198 combinations); consider the varied senses in come to "regain consciousness," come over "possess" (as an emotion), come at "attack," come on (interj.) "be serious," and come off "occur." For sexual senses, see cum.
Related Terms
(also cum) Semen, or any fluid secreted at orgasm (1920s+)
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Diane Marie Xavier
Hilmar, CA
Basic information on Diane Marie Xavier, Hilmar CA. Find Diane Marie Xavier's age, gender, possible aliases, associates and professional status.
Also Known As
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Diane Marie Xavier is in her 50's
Diane Has Lived In
Hilmar, CA
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Zodiac SignTaurus
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Find out where Diane Marie Xavier has lived as well as Diane Marie Xavier's phone numbers and email addresses.
Diane Marie Xavier Has Lived in 1 State
California Address for Diane Marie Xavier
8339 Mxxxxxxx Dx
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'Computer-On-Glass' Display 214 214
from the good-enough-to-lick dept.
Yeah, of course my pc runs on windows...
The answer? Defenestrate now!
I could actually think of a real world application for the fish tank PC, although not as a case mod.
I would just love it, if the front glass of my aquarium would be a PC. Then I could just touch it, and it would display the water temperature, the pH, the salinity and so on directly on the front. Boy, would that be cool. No more Gadgets which destroy the look of the aquarium.
Or through.
The correct term for hardware is "Hack"
I guess "Crash" would be appropriate though.
Yeah? You think so, buddy? Well, what if we decide not to use it, huh? What are YOU going to do about?
Who are you to say if we SHOULD use it or not...
Oh, hold on...that might not be what you meant.
Somethingwicked, you ignorant slut.
Glass is primarily SiO2 or "silica", but what we go around calling glass has plenty of additives. Most of what we call glass is actually soda-lime glass, so called because it contains ample ammounts of soda (Na2O) and lime (CaO). Those two ingredients help lower the melting point of SiO2 and make it a lot easier to process. Pyrex is a brand name for borosilicate glass and its composition allows it to be very strong and resistant to thermal shocks (this is why you can put Pyrex in the oven without worrying about it shattering). LCD glass is probably different alltogether.
Very pure amorphous SiO2 glass can be made, but it is much more expensive and is often sold as "fused silica" or "fused quartz".
True "quartz" is a crystalline (ordered) phase of SiO2, and it is not the only one. Crystoballite and tridymite are two other crystalline phases of quartz.
In any case, SiO2 is a dialectric, and not a semiconductor, so the computation being done in this story is all contained in the layers on top of the glass and not in the glass itself.
How about the front window in cars? Heads-up-display anyone? I may wait on LASIK in hopes that my glasses in 2008 come HUD enabled.I can really see this sort of technology being used on phone booths
Buttons aren't a problem, you can vary capacitance with flexion. (Is that a word?) You can get clear plastic calculators for use on overhead projectors...
Well they're talking about ultra-high resolutions for things like photographs, and maps.
I'm just glad that they're actually mentioning potential applications which aren't a part of the the current buzzword set. They could have easily shoved in there the usual "wireless devices" drivel...
I don't see the significance of this.
"Let's hope this technology does not come to fruition."
"No place to do anything."
The way to make a small fortune in the commodities market is to start with a large fortune.


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Soldiers in Iran dispose of illegal alcoholic products. Oh, the humanity!
11 Conversations That Showcase Why Texting is the Worst
This Siberian Husky Is Anyone After A Few Too Many Edibles
I Support You Not Supporting Me Supporting Them, But Also ...
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Arnold Schwarzenegger Will Terminate You Online
Being Famous Doesn't Make It Easier
You Don't Know The Dinosaur Called Bible?
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First Photos Of Ace Young & Diana DeGarmo In JOSEPH & THE AMAZING TECHNICOLOR DREAMCOAT
An impressive first look at the new production of Andrew Lloyd Webber and Tim Rice's beloved family-friendly Bible-themed musical JOSEPH & THE AMAZING TECHNICOLOR DREAMCOAT starring AMERICAN IDOL standouts and Broadway headliners Ace Young and Diana DeGarmo is now available to view.
Of note, the new JOSEPH & THE AMAZING TECHNICOLOR DREAMCOAT tour, directed by Andy Blankenbuehler, launced at Playhouse Square in Cleveland, OH, on March 4, 2014, with the next stop scheduled for St. Louis at the Fabulous Fox Theatre April 29 - May 11. Additional cities include Cleveland, Tulsa, Oklahoma City, Memphis, St. Louis, Durham, San Jose, Los Angeles, and San Diego.
The official description of the new tour of JOSEPH & THE AMAZING TECHNICOLOR DREAMCOAT is as follows: "One of the most enduring shows of all time, JOSEPH AND THE AMAZING TECHNICOLOR DREAMCOAT is the irresistible family musical about the trials and triumphs of Joseph, Israel's favorite son. The first collaboration of Andrew Lloyd Webber (Jesus Christ Superstar, Phantom of the Opera, Cats) and Tim Rice (Jesus Christ Superstar, The Lion King), JOSEPH blends pop, country and rock into an uplifting, technicolored story of biblical proportions. Retelling the Biblical story of Joseph, his eleven brothers and the coat of many colors, this magical musical is full of unforgettable songs including Those Canaan Days, Any Dream Will Do and Close Every Door."
More information on the new JOSEPH & THE AMAZING TECHNICOLOR DREAMCOAST tour is available at the official site here.
Additionally, check out my extensive recent InDepth InterView with Ace Young and Diana DeGarmo all about the new tour and much more, available here.
View the new photos of Ace Young and Diana DeGarmo in JOSEPH & THE AMAZING TECHNICOLOR DREAMCOAT below.
Photo Credits: Joseph
About Author
- SOUND OFF World Premiere Exclusive: Joel Grey In GEORGE M! On THE ED SULLIVAN SHOW
- SOUND OFF: Four Fabulous Features Of This Week's GLEE
- New Rehearsal Sneak Peek Of SOMETHING ROTTEN! Featuring Christian Borle
- Christian Borle & Brian D'Arcy James Talk SMASH Reunion In Rehearsal For SOMETHING ROTTEN!
- GLEE's Darren Criss & Chris Colfer Explain The Klainomenon
- SHAKESPEARE UNCOVERED: SERIES 2 DVD Out Today
- Behind The Scenes With Matthew Morrison In FINDING NEVERLAND Rehearsals
- Ultra-Glam New KINKY BOOTS Academy Awards Social Media Image
- Darren Criss Says Goodbye To GLEE With Emotional Message To Fans
- Lea Michele, Darren Criss & More In Group Photo Of Cast & Crew At GLEE Finale


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Sounds of the States
It's the fourth of July and the celebration of Independence Day over the pond seems as good an excuse as any to highlight some of the great acts from the States joining us this year!
First Time Friday - part 2
Here's another collection of great artists making their debut appearances at the 2015 Edinburgh Jazz and Blues Festival
Festivals Edinburgh
Edinburgh is the world's Festival City. It's where people come together from across the globe to share their passion for arts, culture and ideas. + more
Visit Edinburgh
Scottish poet Hugh MacDiarmid described the city as 'a mad god's dream', but even the maddest of gods couldn't have dreamt up a more inspiring setting for the world's biggest, most exhilarating, most over-the-top festival. + more


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Play Video
Military excercise
Posted by hnybear36 on Apr. 08, 2010
Break celebrates 4th of July the American Way: by laying the smack down on ...
With the 4th of July around the corner, we celebrate the most kick-ass USA ...
Dude, are you drunk AND high? Or are you just being PRANKED?!
Posted by hnybear36 on Apr. 08, 2010


text: What an exceptional place.. We were stuck in a traffic jam due to an accident, we had been on the road for 8 plus hours. I googled my way around the traffic jam and asked where a nice hotel was. I have stayed at Drury Inns before and have always had a good experience.. When we checked in, the experience... More


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New centre focuses on early childhood research
What does it take to raise a healthy and happy child? That's just one of the questions the 60 faculty members and 50 grad students who make up UVic's new Centre for Early Childhood Research and Policy (CECRP) strive to answer.
Annual awards program lauds local heroes
On Feb. 16, nominees of the 2011 Victoria's Leadership Awards (VLA) were celebrated as exceptional community champions, including this year's recipients of the University of Victoria Community Leadership Awards—Bernie Pauly and Michael Prince.
Free Food...No Foolin'!
The UVic Family Centre is getting ready for its 8th annual "No Foolin'" event on Friday, April 1 from 4:30-6:30 p.m. It will take place outside the family centre in the student family housing complex on Lam Circle. No Foolin' is an opportunity for UVic student families, community supporters and local businesses to come out and celebrate the energy and diversity that families and their children bring to campus life. The annual event is an opportunity to highlight UVic's vibrant family community and help raise awareness about the challenges and barriers that some student families face. Parachute games, relay races, ethnic food, pizza and ice-cream are all part of the free program. Everyone is welcome to attend. For more information contact email@example.com.
Sandborn, Pauly, honorary citizens
Victoria city council has selected Environmental Law Centre legal director Calvin Sandborn (law) and Bernie Pauly (nirsing, psychology) as two of the city's 14 honourary citizens for 2011. The award was presented on Jan.19 by Mayor Dean Fortin, in recognition of Sandborn's contributions to environmental protection and sustainability education on Vancouver Island and Pauly's community work on social issues, including homelessness.
Dr. Lenora Marcellus
Dr. Lenora Marcellus (nursing) and members of Vancouver Island's Safe Babies Program have been awarded the 2010 Rotman Award for Pediatric Home Care Innovation. The program provides education and support for foster families caring for infants with prenatal substance exposure and is the result of years of partnership between the Vancouver Island Health Authority (VIHA), Ministry of Children and Family Development and the Foster Parents Support Services Society. The $100,000 award will be used to further expand the program across BC and roll out a new training curriculum.
In memoriam: Elias Chaboud
Dr. Elias Cheboud (1959–2010) was a remarkable colleague and friend who died very suddenly on Dec. 12 while working outside Addis Ababa, Ethiopia, doing what he loved: working for peace alongside colleagues from around the globe. A memorial service for colleagues, alumni, family and friends took place on Dec. 20 at the Interfaith Chapel.
Lau awarded
Dr. Francis Lau (health information science) is the recipient of the 2010 Canadian Health Informatics Award for outstanding leadership in the field of health informatics. Lau's work was recognized at a gala event in Toronto hosted by the Canadian Health Informatics Association and the Information Technology Association of Canada. Lau heads up the eHealth Observatory, a national research initiative, jointly funded by the Canadian Institutes for Health Research and Canada Infoway, to monitor the impact of health information system deployment and electronic records adoption in Canada. He holds the Applied Health Services and Policy Chair in eHealth. More info: http://ehealth.uvic.ca/
Stajuhar, Funk awarded
Dr. Kelli Stajuhar (nursing and Centre on Aging) and post-doctoral student Laura Funk recently received the Anselm Strauss Award, a prestigious research honor from the US National Council on Family Relations—a professional association for the multidisciplinary understanding of families. They were acknowledged for a cutting-edge article critiquing methods used in research on families. They claim that one downfall of basing research on interviews alone is that sometimes what people say and what they do are very different. They recommend addressing this by repeating interviews over a long period of time and combining them with observation.
Every picture tells a story
Grad promotes social entrepreneurship
From an early age Master's of Public Administration (MPA) graduate Kanika Gupta learned the importance of commitment to community. In high school she started a club to promote volunteering as a way of meeting new people, discovering the community and having fun. Today, she continues to use innovative ways to engage youth around social responsibility.
Most popular
- 13,000-year-old footprints
- UVic celebrates with Pride
- 2015 Craigdarroch Research Awards
- Wild game and words
- Vikes band course
- Campus communications project
- UVic celebrates with Pride
- 13,000-year-old footprints
Media releases
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View my Flipboard Magazine.


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Newly trained orthopaedic surgeons are ready to set up practice at regional hospitals across rural Uganda, except the operating rooms aren't equipped with the high-tech tools they need.
The first fundraiser for the Sensor Project was held on May 28, 2015, raising more than $13,000 for a life-saving initiative in the developing world led by UBC clinicians and scientists.
Chew Wei came to Vancouver late in his life. Tak Wah Mak made the same journey in his youth – first to the U.S., then to Canada. But the two men had much more than their migration in common: They also contributed mightily to cancer research in their adopted homeland.
The patients who come to the Faculty of Medicine's eye clinic on East Hastings Street have conditions rarely encountered in the rest of Vancouver: repeated eye trauma, damage from HIV-related infections, venereal infections in the eyes, talc from injected cocaine blocking blood vessels. Such is the nature of ophthalmology in the Downtown Eastside.
Chuck Fipke expected nothing but the usual cheer and festivity at the Christmas party he held a few years ago for friends and business associates in Kelowna. But that year's gathering was marred by some disturbing news from one of his guests, Brad Bennett.
Lara Boyd explores whether an unorthodox curriculum has a neurological impact on children.
Read more…
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To donate, contact Adrienne Lariviere at 604.822.5664 or firstname.lastname@example.com. Or...
Find out about all the ways you can donate to UBC, including the tax benefits of donations.
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Aliases for CSNK1A1 Gene
Aliases for CSNK1A1 Gene
External Ids for CSNK1A1 Gene
- Entrez Gene: 1452
- Ensembl: ENSG00000113712
- UniProtKB: P48729
Summaries for CSNK1A1 Gene
GeneCards Summary for CSNK1A1 Gene
CSNK1A1 (Casein Kinase 1, Alpha 1) is a Protein Coding gene. Diseases associated with CSNK1A1 include lung cancer. Among its related pathways are Signaling by GPCR and GPCR Pathway. GO annotations related to this gene include protein serine/threonine kinase activity and protein kinase activity. An important paralog of this gene is CSNK1G2.
UniProtKB/Swiss-Prot for CSNK1A1 Gene
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at Ser-45. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.
Casein kinase I (CK1) is a monomeric serine-threonine protein kinase with 7 isoforms: alpha, beta, gamma1, gamma2, gamma3, delta and epsilon. CK1 is involved in a number of cellular processes including DNA repair, cell division, nuclear localization and membrane transport. CK1 isoforms also have key roles in the developmentally important Wnt and Hedgehog (Hh) signaling pathways. When Wnt is not bound to its receptor, CK1alpha is thought to phosphorylate beta-catenin as part of its degradation process. Upon binding of Wnt to its receptor (Frizzled) CK1epsilon phosphorylates the intracellular signaling protein, Dishevelled and CK1gamma directly phosphorylates the LRP5/6 co-receptor. These actions of CK1 facilitate signal transduction to the transcription factor, TCF, which mediates transcription of Wnt regulated genes. Similarly, CK1alpha plays a role in regulating Hh signaling by phosphorylating the signaling effector Ci-155 in the Hh unbound state, and then when Hh binds to Patched, CK1alpha phosphorylates the 7-TM co-receptor, Smoothened.


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Deep, Sensitive, Thought-Provoking Nov 4, 2013
by Timothy C
A boy, accompanied by his father, searches for his grandfather's name on the Vietnam War Memorial. Together, they run their hands along the black, reflective surface, fingers tracing the names of the fallen. The boy sees the mementos left at the base of the wall and watches other visitors as they come and go. With his father, the boy finds his grandfather's name and learns new lessons about grief, sacrifice, and honor. As the pair turn to go, the boy thinks to himself that he is proud that his grandfather's name is on the Wall, but his last words reflect the deep sense of loss and regret that the Memorial inspires in each of us. "I'd rather have him here."
I love this book for so many reasons. I chose it because Veteran's Day is coming up and I wanted to see how picture books handle a topic as sensitive as war. This book finds such a great balance between honoring our fallen soldiers, cherishing their memory, and mourning both the personal and national loss of so many good and too often young lives when nations go to war. I love the descriptions of the Wall, the people, the gloomy autumn day, the father running his hands over and over the name of his dead father. I cannot read this book without crying.
Let's talk about my daughters' reactions. My four year old was a total buzz kill, just complaining the whole time that it wasn't more entertaining. Oh well. But my two year old was a little more sensitive. Before we started reading, she took a good look at the cover picture and asked me why the father and son were so sad. Perfect reaction, and just what a book like this should inspire- questions and discussions about real, deep emotions that are difficult to discuss in the normal course of a two-year-old's life. It brings things up that are normally not brought up and allows us to discuss them in the context of a story about believable but imaginary characters. My seven year old was also curious and asked lots of questions, and we had some great discussions about the cost of war and the importance of making sure that what you're fighting for is worth that cost. Conclusion: this will never be a bedtime favorite, but I would recommend it a thousand times over for anyone and everyone.


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Report Writing: Note Taking
In this segment, William Fogarty suggests the author of a report needs to ensure that he/she understands the need to take good notes which do not use abbreviations unless he/she will be the only reader. In addition, it is important that the report author understands the definitions of all words that they use while writing the report, including those made during witness statements.
Join the discussion
PoliceOne top 5
- 1 10 secrets cops know that most people don't
- 2 Video: Texas cops fatally shoot man who pulled replica
- 3 Chicago police officers sue over tattoo cover-up rule
- 4 Police warn public against using iPhone cases shaped like guns
- 5 Video: Cuffed Ark. woman steals, crashes cruiser


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Walmart.com's 'Made in the USA' claims lead to fireworks
An advertising watchdog's report found dozens of claims that it says were false and deceptive. Wal-Mart blames suppliers.
Walmart.com's 'Made in the USA' claims lead to fireworks
An advertising watchdog's report found dozens of claims that it says were false and deceptive. Wal-Mart blames suppliers.
Amazon launches full retail and marketplace offerings in Mexico
Amazon.com.mx previously has sold Kindle e-books since its launch in 2013.
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Sponsored by 2013 Social Media 300
Although the U.S. Department of Commerce reports online sales rose 14% in the second quarter over the same period a year ago, Internet measurement firm comScore Inc. warns that growth may slow down without more online spending by middle-income shoppers.
Online retail sales grew 14.0% in the second quarter over the same period a year earlier, the U.S. Commerce Department says, marking the third straight three-month period of at least 14% growth following a year-long slump during the recession. But comScore Inc., which tracks the spending of online shoppers, says growth may slow unless middle-income shoppers start buying more online.
The Commerce Department reported that seasonally adjusted e-commerce spending during the second quarter reached $39.7 billion, up 2.6% from the first quarter. The 14.0% year-over-year growth rate in Q2 follows 14.3% growth in the first quarter and 14.6% growth in the fourth quarter of 2009.
Total retail sales in the second quarter grew 7.5% from a year ago to $971.4 billion, making e-commerce sales 4.1% of the total, the Commerce Department said. However, after excluding sales in categories not commonly bought online—automobiles, fuel, grocery and restaurant sales—Internet Retailer calculates e-commerce accounted for 7.3% of retail sales in categories where web retailers typically compete with bricks-and-mortar stores, down slightly 7.9% from in the first quarter.
Without the seasonal adjustment, the U.S. Census Bureau estimates second quarter e-commerce sales reached $37.2 billion, up 1.5% from the first quarter and 13.7% more than during the second quarter of 2009. Non-adjusted e-commerce sales represented 3.8% of total retail sales in the second quarter. Total non-adjusted retail sales were $988.9 billion, up 10.3% from the first quarter and 7.5% from Q2 of 2009.
The Commerce Department report, which is based on a quarterly survey of 12,000 retailers, followed the release of a lower Q2 estimate from comScore Inc., which tracks a panel of online consumers. ComScore estimated e-commerce spending of $32.9 billion, up 8.9% from its estimate for the second quarter of last year. Gian Fulgoni, comScore chairman, says when comparing comScore data with the same categories tracked by the Commerce Department comScore's growth figure would be about 11%.
Fulgoni says year-to-date online spending has been strong, but expressed caution about the future. "The job market seems to have lost momentum and could lead to weak spending in the third quarter," he says.
He also highlighted the weakness in online spending of middle-income households in July 2010, which was 8% lower than it was in July 2008, before the recession fully took hold. Those households account for 41% of online spending, Fulgoni says.
Growth in July came from low- and high-income shoppers. Online spending for households earning less than $50,000 was up 14% in July versus July 2008, while households earning more than $100,000 increased online spending by 28%.
Russian shoppers use a variety of domestic e-wallets quite often when shopping online, a result ...
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The astronomical growth of Alibaba's Taobao online shopping mall is hard to fathom from a ...
Posted 06/27/15
If there's something you've bought offline that you weren't able to buy online, we're probably thinking about that."


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- Film, Media & Entertainment
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UX London 2013
Clearleft Ltd
Wednesday, 10 April 2013 at 09:00 - Friday, 12 April 2013 at 17:00 (BST)
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We're dedicated to bringing you the best conference experience possible, so we set out to re-invent the event for 2013. We've changed the venue, the format, and the ticket structure, all to make this event like no other UX conference you've attended before.
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CEA is hosting a contest with the opportunity to have a piece of your music featured as the music bed for the CES 2016 keynote opening video.
The Supreme Court for Innovation: Apply Now to Judge the CES 2016 Innovation Awards.
Registration is now open for the third annual CES Unveiled Paris which will be held on Wednesday, October 21, 2015 at the Pavillon Cambon-Capucines in Paris, France.
Sign up now to be notified when 2016 CES registration will open.
Book your hotel room for CES 2016 in Las Vegas.
See CES from the eyes of those who lived it.
Here's what the CES show floor looked like in 1997.
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London, United Kingdom
Last login about 2 months ago
Join Couchsurfing to see Gerit's full profile. It's free!View Full Profile
I am outgoing, friendly and usually I am trying to keep myself busy with different activites. I am curios, I like to try new things and get new experiences (try new dishes, learn about cultures, try different sports etc). I like to have people around me, but sometimes I just love being on my own, discovering new places/photographing etc just by myself. I am purposeful, so if I want something I do everything depending on me to achieve it. I like creating stuff. I think there is too much to discover and experience in the world to stay too long in one place, so in recent years I have been living in different places and really enjoyed it, my last change was to move from Denmark, where I lived on and off for two years, to London to finish my design degree here.
"Twenty years from now you will be more disappointed by the things that you didn't do than by the ones you did do. So throw off the bowlines. Sail away from the safe harbor. Catch the trade winds in your sails. Explore. Dream. Discover." - Mark Twain
Right now I can just surf, as I don`t have my own place to host people, but I am up to meet and hang out with new people.
I don`t have a lot of experience with hosting in CS, although I have hosted some people outside of CS.
Travelling, photography, design, art, reading, experiences, cooking
Books: "Ensemble, c`est tout" by Anna Gavalda (actually all of her books, she is just amazing writer); real-life stories (like "Married To A Bedouin", "Desert Flower" etc); travelling books
Although I don`t mind to listen every kind of music, depending on my mood, but I mostly enjoy Fun., Feist, Mumford & Sons, Ewert and the Two Dragons, The xx, Little Dragon, Welcome Back Sailors, as well as Coldplay, The Beatles, Queen, Aerosmith. And I also really like Estonian music from 70s-80s, for example Urmas Alender, Ruja etc.
Movies: Seven Years in Tibet, Love Actually
Parachute jump on summer 2011; mountain hiking in Venezuelan Andes;
I really want to learn how to surf and also to play guitar.
I can teach piano, photographing, languages I speak
Belgium, Bulgaria, Denmark, Estonia, Finland, France, Germany, Gibraltar, Greece, India, Italy, Latvia, Lithuania, Luxembourg, Monaco, Netherlands, Portugal, Russian Federation, Slovakia, Spain, Sweden, Tunisia, Turkey, United Kingdom, Venezuela
Denmark, Estonia, Spain, United Kingdom, Venezuela
Join Couchsurfing to see Gerit's full profile. It's free!View Full Profile


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Last night was truly a blessing. Catching up with a dear old friend who has also experienced brokenness has been truly worthwhile and edifying. To hear her journey and what she has learned has helped me realize I'm not alone. 482 more words
Tags » Wise Advice
Walking with the Wise
Sensible people keep their eyes glued on wisdom,
but a fool's eyes wander to the ends of the earth.- Prov 17:24
As I did my quiet time today, I thank You Lord for these two verses which sharpened me in such a way along with the story of Esau this morning making the bad decision of selling his birthright out of hunger. 651 more words
This message by Andy Stanley was very timely. I believe we all know we need to set boundaries but one thing is to know another is to actually have them in effect. 243 more words
You have a purpose.
21 more words
That's what they all say.
"You are here for a purpose"
That's what they all say
To this day,
I think no one really knows what it means…
smashing advice for one's twenties
…some of the best I've come across yet. Must keep this in mind. Note to self: refer back frequently.
Once again, I'm indebted to awelltraveledwoman… 400 more words
They said.
They said:
"Look from within and you will find peace"
And so I searched my soul
And found a waterfall
Of emotions unexpressed
Words unsaid… 7 more words
If ever releasing a squirrel (and trust me, if you live in the country you will need to do this at some point), make sure you do not do this in the middle of a field. 39 more words


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The 24-year-old daughter of Philadelphia City Treasurer Nancy Winkler was among the six people killed when a demolition went horribly awry and crushed the well-known Salvation Army store at 22nd and Market Streets.
Anne Bryan, a student at Pennsylvania Academy of the Fine Arts, was described by her family as "an extremely talented artist" who "possessed a passion for the arts and an ability to find beauty in everything around her."
Bryan's family released a statement through the academy, whose CEO and President David R. Brigham said the school would hold a memorial for Bryan in the near future.
"Anne will be remembered here at PAFA by her friends and faculty as dynamic, inquisitive and smart," Brigham said. "She believed in the importance of art, took her work seriously, and was very committed to learning, improving her skills and exploring different mediums as a means of expressing complex ideas. She described PAFA as a thought-provoking community where students are challenged by teachers and peers, and share a passion for art, growth, and achieving artistic goals."