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UAM. Cartoteca "Rafael Mas". Inventario, 2011 2 UAM. Cartoteca "Rafael Mas". Inventario, 2011 3
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#12;UAM. Cartoteca "Rafael Mas". Inventario, 2011 2 #12;UAM. Cartoteca "Rafael Mas". Inventario Madrid. En 2008 se incorporaron, tambiûˋn como donaciû°n de la #12;UAM. Cartoteca "Rafael Mas". Inventario://biblioteca.uam.es - Este inventario, disponible en soporte papel y en la red, en la dir
Autonoma de Madrid, Universidad
JosÕ Rafael Moneo VallÕs: 1965-1985
Rafael Moneo, a Spanish architect and educator who has been practicing architecture in Madrid since 1965, rose in the profession from local practitioner to designer of international reputation in the mid-1980s with his ...
Koukoutsi-Mazarakis, Valeria E., 1962-
Herman M Cho | EMSL
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
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Characterization of four CHO mutants
or the pleiotypic response in which a set of metabolically unrelated biochemical reactions respond coordinately to changes in the environ- ment that affect cellular growth. Rates of growth, amino acid uptake, protein synthesis, protein degradation, and DNA..., and CHO-T2S:24 to 2. 26'%%d per hour and inhibited rates of protein degradation in all four cell lines to 1. 54'%%d per hour. However, in CHO-T2S:24AB3, the positive pleiolypic activators only stimulated rates of protein synthesis to 1. 72'/. per hour...
Brancheau, Michael Raymond
Rafael L. Bras | Department of Energy
Office of Environmental Management (EM)
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of Energy Power.pdf11-161-LNG |September 15,2015 | DepartmentLoansDepartment of EnergyEvent |Rafael L.
Sliding Friction with Polymer Brushes Rafael Tadmor,* Joanna Janik,
across the polymer layers decays logarithmically with time, consistent with the relaxation of a network on the sliding velocity, an effect attributed to a velocity-dependent interpenetration of the opposing polymerSliding Friction with Polymer Brushes Rafael Tadmor,* Joanna Janik, and Jacob Klein Department
Klein, Jacob
Fabrication Technologies for Three-Dimensional Integrated Circuits Rafael Reif
Fabrication Technologies for Three-Dimensional Integrated Circuits Rafael Reif Dept. of Electrical Engineering and Computer Science, MIT Cambridge, MA firstname.lastname@example.com Andy Fan Dept. of Electrical Engineering, MIT Cambridge, MA email@example.com Shamik Das Dept. of Electrical Engineering and Computer Science, MIT
He, Lei
Local Harmonic Estimation in Musical Sound Rafael A. IRIZARRY
Local Harmonic Estimation in Musical Sound Signals Rafael A. IRIZARRY Statistical modeling so a local harmonic model that tracks changes in pitch and in the amplitudes of the harmonics is fit estimates of the harmonic signal and of the noise signal. Different musical composition applications may
Irizarry, Rafael A.
La nueva edicin de Infotgrafos de la UA contar con el prestigioso fotgrafo Rafael Navarro
La nueva ediciû°n de Infotû°grafos de la UA contarûÀ con el prestigioso fotû°grafo Rafael Navarro como Rafael Navarro, GermûÀn Gû°mez, Pepe Soto y Carlos Balsalobre. Durante este foro sobre fotografûÙa, coordinador de Infotû°grafos III. Ponencias Rafael Navarro (Zaragoza, 1940), que celebrarûÀ su conferencia el 11
Escolano, Francisco
San Rafael, California: Energy Resources | Open Energy Information
Open Energy Info (EERE)
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 No revisionEnvReviewNonInvasiveExplorationUT-g Grant ofRichardton Abbey WindSamsungFarms SectorMateo,Rafael,
E-Print Network 3.0 - atuel-1 san rafael Sample Search Results
Landing (Site) Napa Sonoma Vallejo Richmond Petaluma Sausalito San Rafael Bodega Bay Sebastopol Santa Rosa... Estero de San Antonio ( 6536 acres) 13,418 Hectares 4th Field HUC...
Optimizing microalgal production in raceway systems Rafael Mu~noz-Tamayoa
have been10 identified as a renewable source for biodiesel production [5, 18]. However, despite these11Optimizing microalgal production in raceway systems Rafael Mu~noz-Tamayoa , Francis Maireta is characterized by the production of high value compounds. Optimization of the performance of microalgae culture
Boyer, Edmond
THE INFINITY LAPLACIAN WITH A TRANSPORT TERM RAFAEL LôÇOPEZ-SORIANO, JOSôÇE C. NAVARROôÇOPEZ-SORIANO, J. C. NAVARRO-CLIMENT AND J. D. ROSSI our purposes let us assume that is a gradient vector field
Rossi, Julio D.
Load Reduction of Wind Turbines Using Receding Horizon Control Mohsen Soltani, Rafael Wisniewski, Per Brath, and Stephen Boyd
Load Reduction of Wind Turbines Using Receding Horizon Control Mohsen Soltani, Rafael Wisniewski, Per Brath, and Stephen Boyd Abstract-- Large scale wind turbines are lightly damped mechanical% respectively, when compared to a conventional controller. I. INTRODUCTION The size of wind turbine structures
Understanding Pollution Dynamics in P2P File Sharing , Junghoo Cho
Understanding Pollution Dynamics in P2P File Sharing Uichin Lee , Min Choi , Junghoo Cho , M. Y,cho,medy,email@example.com, firstname.lastname@example.com ABSTRACT Pollution in P2P file sharing occurs when a large number of decoy files that pollution dynamics are closely related to user behavior. Therefore, we first conduct a human subject study
Cho, Junghoo "John"
E-Print Network 3.0 - antibody-producing cho cell Sample Search...
spatially at random throughout... . The phantoms were biological phantoms made of agar and containing either 4T1 mouse carcinoma cells or CHO cells... BcmMHz in phantoms...
Active hypothermic growth : a novel means for increasing total recombinant protein production by CHO cells
Recombinant human glycoproteins produced by Chinese Hamster Ovary (CHO) cells are an important class of therapeutic molecules and investigating means of improving the production rate and product quality of these glycoproteins ...
Fox, Stephen Richard
A C-H...O Hydrogen Bond Stabilized Polypeptide Chain Reversal Motif
A C-H...O Hydrogen Bond Stabilized Polypeptide Chain Reversal Motif at the C-terminus of Helices between the C atom of residue Ala 4 (T-4) and the backbone oxygen atom of DLeu 9. The C-H...O hydrogen Nitrogenase MoFe protein (PDB: 1qh8). The N-H...O hydrogen bond parameters are: O...N = 3.19û?; O...H = 2.48 û?
Babu, M. Madan
C-H..O Hydrogen Bonds in Minor Groove of A-tracts in DNA Double Helices
C-H..O Hydrogen Bonds in Minor Groove of A-tracts in DNA Double Helices Anirban Ghosh and Manju-pair as well as cross-strand C-H..O hydrogen bonds in the minor groove. The C2-H2..O2 hydrogen bonds within leads to a narrow minor groove in these regions. # 1999 Academic Press Keywords: C-H..O hydrogen bonds
Bansal, Manju
Dose-rate-effects in XRCC1 wild-type and mutant CHO cell lines using An ý?¿AM source
This work explores the effects of low-dose-rate radiation on both the AA8 (wild-type CHO cells) and EM9 (XRCC1 null CHO mutants) cell lines. In particular, this study performed clonogenic survival and growth assays to ...
Chambers, Dwight McCoy
Dynamic isotope effect on the product energy partitioning in CH2OH ~CHO H2
Dynamic isotope effect on the product energy partitioning in CH2OH ~CHO H2 Young Min Rheea March 1998; accepted 1 July 1998 The deuterium isotope effect on the product energy partitioning. Close inspection of the potential energy surface revealed that the isotope effect on KER and the product
Kim, Myung Soo
Wind buffeting effects on the Gemini 8m primary mirrors M. K. Cho1,2
Wind buffeting effects on the Gemini 8m primary mirrors M. K. Cho1,2 , L. Stepp1 , and S. Kim3 and Mechanical Engineering, University of Arizona, 1130 N. Mountain, Tucson, AZ 85721 #12;Wind buffeting effects mirror distortion caused by wind pressure variations. To quantify telescope wind loading effects
Performance of Graceful Degradation for Cache Faults Hyunjin Lee Sangyeun Cho Bruce R. Childers
Performance of Graceful Degradation for Cache Faults Hyunjin Lee Sangyeun Cho Bruce R. Childers to thermal hot spots) and may man- ifest themselves as operational faults at the micro- Bruce Childers that is dependent on the fault and the frequency of access to an address that would normally be held in the disabled
Cho, Sangyeun
Demo Abstract: Energy Transference for Sensornets Affan A. Syed Young Cho John Heidemann
Demo Abstract: Energy Transference for Sensornets Affan A. Syed Young Cho John Heidemann USC continuous monitoring, 24x7, at remote, inaccessible locations making energy man- agement a critical part of most sensornets. The sensornet research community has explored energy conservation and energy
Heidemann, John
Johan Ren van Dorp, Salvador Cruz Rambaud, Jos Garca Prez, and Rafael Herreras Pleguezuelo (2007). "An Elicitation Procedure for the Generalized Trapezoidal Distribution with a Uniform Central Stage", Decision Analysis Journal, Vol. 4, pp. 156 -166.
Johan Renûˋ van Dorp, Salvador Cruz Rambaud, Josûˋ GarcûÙa Pûˋrez, and Rafael HerrerûÙas Pleguezuelo University, USA1 Salvador Cruz Rambaud , University of AlmerûÙa, Spain2 Josûˋ GarcûÙa Pûˋrez , firstname.lastname@example.com #12;Johan Renûˋ van Dorp, Salvador Cruz Rambaud, Josûˋ GarcûÙa Pûˋrez, and Rafael HerrerûÙas Pleguezuelo
van Dorp, Johan Renûˋ
Photodissociation spectroscopy and dynamics of the vinoxy (CH{sub 2}CHO) radical
SciTech Connect (OSTI)
The photodissociation spectroscopy and dynamics of the vinoxy (CH{sub 2}CHO) radical have been studied using fast beam photofragment translational spectroscopy. The photodissociation cross section over the B{sup 2}A{double_prime} {l_arrow} X{sup 2}A{double_prime} band is measured, and photofragment translational energy and angular distributions are obtained at several excitation energies. For CH{sub 2}CHO, predissociation is observed over the entire band, including several transitions near the band origin which were seen previously in laser-induced fluorescence experiments. Two dissociation channels are seen: CH{sub 3} + CO and H + CH{sub 2}CO. The CH{sub 3} + CO channel was investigated in considerable detail and appears to proceed via internal conversion to the CH{sub 2}CHO ground state followed by isomerization to CH{sub 3}CO and subsequent dissociation. The translational energy distributions for this channel suggest an isomerization barrier in the range of 2 eV with respect to CH{sub 3} + CO products.
Osborn, D.L.; Choi, H.; Neumark, D.M. [Univ. of California, Berkeley, CA (United States). Dept. of Chemistry]|[Lawrence Berkeley Lab., CA (United States). Chemical Sciences Div.
Observation of Weak C-H...O Hydrogen Bonding by Unactivated Alkanes. | EMSL
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the ContributionsArmsSpeedingSpeedingUnder Well-Controlled TemperatureWeak C-H...O
7. I. Aramori and S. Nakanishi, ibid. 8, 757 (1992). 8. CHO cells expressing mGluR1 or MEF cells trans-
-intensified targeted vid- eo camera with Ca2 -sensitive fluorescent dye fura 2-AM, as described (7). Inhibitors were7. I. Aramori and S. Nakanishi, ibid. 8, 757 (1992). 8. CHO cells expressing mGluR1 or MEF cells 10 min be- fore the application of agonists. CHO cells were lysed in tris-NP40-EDTA ( TNE) buffer [H
Cushing, Jim. M.
Test Set Reordering Using the Gate Exhaustive Test Metric Kyoung Youn Cho and Edward J. McCluskey
Test Set Reordering Using the Gate Exhaustive Test Metric Kyoung Youn Cho and Edward J. Mc email@example.com Abstract When a test set size is larger than desired, some patterns must be dropped. This paper presents a systematic method to reduce test set size; the method reorders a test set
Stanford University
Effect of continuous irradiation on proliferation of CHO-K1 and xrs-6 cells under low and high oxygen conditions
The goals of this research were to determine: 1) the effect of continuous irradiation on Chinese Hamster Ovary cells, CHO-K1 (wild type) and xrs-6 cells (mutant), and 2) the effect of continuous irradiation under low (5%) ...
Vu, An T
VSoE RIF Report: Micro-Tomography P.I.: Young H. Cho, Research Assistant Professor, Dept of EE/Dept of CS
VSoE RIF Report: Micro-Tomography P.I.: Young H. Cho, Research Assistant Professor, Dept of EE to the expense of buoys, floats or robotic probes. By performing acoustic tomography between shore or buoy
Zhou, Chongwu
Comparison of benzo(a)pyrene metabolism and mutation induction in CHO cells using rat liver homogenate (S9) or Syrian hamster embryonic cell-mediated activation systems
Mutagenesis in CHO cells has been studied by the addition of an ezymatically active liver homogenate (S9) fraction. However, the metabolism of procarcinogens, such as benzo(a)pyrene (B(a)P), by rat liver homogenate differs from that in intact cellular activation systems. Consequently, B(a)P-induced mutation frequencies in mammalian cells may vary when different activation systems are used. This study attempts to compare B(a)P metabolism and conjugation in rat liver homogenate (S9 preparation) and in Syrian hamster embryonic (SHE) cells. Furthermore, a CHO mutation assay incorporating either of the activation systems is being used to measure the mutation induction frequency.
Chen, D.J.; Okinaka, R.T.; Strniste, G.F.
Control of silicidation in HfO2/Si,,100... interfaces Deok-Yong Cho, Kee-Shik Park, B.-H. Choi,a
like nitrogen.6,7 Among these, Hf-silicide is probably most detrimental since it is metallic and degrades the capacitor performance. Metal- lic Hf-silicide formation has been reported in the interfaceControl of silicidation in HfO2/Si,,100... interfaces Deok-Yong Cho, Kee-Shik Park, B.-H. Choi
Oh, Se-Jung
A Collision Attack on AURORA-512 NTT, 3-9-11 Midori-cho, Musashino-shi, Tokyo, 180-8585 Japan
A Collision Attack on AURORA-512 Yu Sasaki NTT, 3-9-11 Midori-cho, Musashino-shi, Tokyo, 180-8585 Japan Abstract. In this note, we present a collision attack on AURORA-512, which is one of the candidates for SHA-3. The attack complexity is ap- proximately 2236 AURORA-512 operations, which is less than
Expression of orphan G-protein coupled receptor GPR174 in CHO cells induced morphological changes and proliferation delay via increasing intracellular cAMP
Highlights: Black-Right-Pointing-Pointer Expression of GPR174 in CHO cells induces morphological changes and proliferation delay. Black-Right-Pointing-Pointer These are due to increase in intracellular cAMP concentration. Black-Right-Pointing-Pointer Lysophosphatidylserine was identified to stimulate GPR174 leading to activate ACase. Black-Right-Pointing-Pointer The potencies of fatty acid moiety on LysoPS were oleoyl Greater-Than-Or-Slanted-Equal-To stearoyl > palmitoyl. Black-Right-Pointing-Pointer We propose that GPR174 is a lysophosphatidylserine receptor. -- Abstract: We established cell lines that stably express orphan GPCR GPR174 using CHO cells, and studied physiological and pharmacological features of the receptor. GPR174-expressing cells showed cell-cell adhesion with localization of actin filaments to cell membrane, and revealed significant delay of cell proliferation. Since the morphological changes of GPR174-cells were very similar to mock CHO cells treated with cholera toxin, we measured the concentration of intracellular cAMP. The results showed the concentration was significantly elevated in GPR174-cells. By measuring intracellular cAMP concentration in GPR174-cells, we screened lipids and nucleotides to identify ligands for GPR174. We found that lysophosphatidylserine (LysoPS) stimulated increase in intracellular cAMP in a dose-dependent manner. Moreover, phosphorylation of Erk was elevated by LysoPS in GPR174 cells. These LysoPS responses were inhibited by NF449, an inhibitor of G{alpha}{sub s} protein. These results suggested that GPR174 was a putative LysoPS receptor conjugating with G{alpha}{sub s}, and its expression induced morphological changes in CHO cells by constitutively activating adenylyl cycles accompanied with cell conjunctions and delay of proliferation.
Sugita, Kazuya; Yamamura, Chiaki; Tabata, Ken-ichi [Laboratory of Pharmacoinformatics, Graduate School of Ritsumeikan University, Kusatsu, Shiga 525-8577 (Japan)] [Laboratory of Pharmacoinformatics, Graduate School of Ritsumeikan University, Kusatsu, Shiga 525-8577 (Japan); Fujita, Norihisa, E-mail: email@example.com [Laboratory of Pharmacoinformatics, Graduate School of Ritsumeikan University, Kusatsu, Shiga 525-8577 (Japan) [Laboratory of Pharmacoinformatics, Graduate School of Ritsumeikan University, Kusatsu, Shiga 525-8577 (Japan); School of Pharmacy, Ristumeikan University, Kusatsu, Shiga 525-8577 (Japan)
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Naive Filterbots for Robust Cold-Start Recommendations Seung-Taek Park1
independent community-driven web sites to e-commerce powerhouses. Once a substantial amount of preference data in cold-start user, cold-start item, and cold-start system settings. Performance is better when data is scarce, per- formance is no worse when data is plentiful, and algorithm efficiency is negligibly affected
Madani, Omid
Use of a transfected and amplified Drosophila heat shock promoter construction for inducible production of toxic mouse c-myc proteins in CHO cells
After transfection and selection with methotrexate, CHO cell lines were established which contained up to 2000 copies of an expression vector for c-myc protein. The vector contained the Drosophila heat shock protein 70 (hsp70) promoter fused with the coding region of the mouse c-myc gene. Incubation of cells for up to 3 hours at 43/sup 0/C resulted in at least a 100-fold induction of recombinant c-myc mRNA. When cells were shifted back to 37/sup 0/C, within 1 to 4 hours, this RNA was translated into protein to yield about 250 ..mu..g per 10/sup 9/ cells. Cells died a few hours later, suggesting that high concentrations of intracellular c-myc are cytotoxic. 47 refs., 5 figs.
Wurm, F.M.; Gwinn, K.A.; Papoulas, O.; Pallavicini, M.; Kingston, R.E.
Nano-Fabricated Extracellular Matrix Topography could Alter the Cancer Cell Behavior Kasun A. Gardiye Punchihewa1, Se Yong An1, Michael Cho2, Sarah Glover3and Vitali Metlushko1*
. Gardiye Punchihewa1, Se Yong An1, Michael Cho2, Sarah Glover3and Vitali Metlushko1* 1Department Glover. Cancer Cell International 2010, 10:24 This research brings together a team of interdisciplinary biology (Dr. Sarah Glover, UIC College of Medicine), cellular biomechanics and multimodal imaging (Dr
Metlushko, Vitali
LS-l Y. Cho
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmospheric Optical Depth7-1D: VegetationEquipment Surfaces and Interfaces Sample6, 2011 LOS ALAMOS, NewattractsDamping s.LS-I03 G.Kiml
Energy Savers [EERE]
department and Director of the Ralph M. Parsons Laboratory at MIT. He has served as advisor to many government and private institutions. Some of the most significant include:...
Amazonas Susteinable Foundation Rafael Salles Valente
of species Occurency of species Management Bring information to biodiversity conservation programs. Management Bring information to biodiversity conservation programs. Access by shipsAccess by ships #12 - Social #12;Monitoring Objectives ôñ Deforestation ôñ Social and economic ôñ Biodiversity #12;Deforestation
Rafael Saer | Photosynthetic Antenna Research Center
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 -the Mid-Infrared at 278, 298, and 323Program2
Comparison of protein patterns of xrs-5, a radiosensitive Chinese hamster ovary cell line, and CHO-K1, its radioresistant parent, using two-dimensional gel-electrophoresis
X-ray sensitive strains of Chinese hamster ovary cell lines have been used to analyze radiation repair mechanisms. One cell line, xrs-5, has been shown to be very sensitive to ionizing radiation and radical forming chemical mutagens. This sensitivity is thought to be a result a mutation in the DNA double strand break (DSB) repair mechanism, and its characterization has been a goal of several repair mechanism studies. Using two-dimensional gel electrophoresis, we have detected a protein (MW approximately 55KD) in the DNA/Nuclear Matrix (nucleoid) cell fraction of CHO-Kl cells that is absent in the nucleoid fraction of xrs-5. This protein is present, however, in both CHO-Kl and xrs-5 whole cell protein maps. To determine whether the 55KD protein is responsible for the radiosensitive and defective DSB repair phenotype of xrs-5 cells, studies are now underway to analyze revertants of xrs-5 that are proficient in DSB repair. Furthermore, an effort to sequence the protein in question is planned. 23 refs., 2 figs.
Kramer, J.M. (Miami Univ., Oxford, OH (USA). Dept. of Zoology)
Homoclinic and heteroclinic connections Rafael Ramirez-Ros
, September 15ôÙ19, 2008 ôÙ p. 2/4 #12;Plan and warnings Plan: Explain the simplest example: a "fish/4 #12;Fish-shaped separatrix (Unperturbed setup) We begin with a "fish-shaped" homoclinic connection.) If a branch of the unstable curve coincides with another branch of the stable one, they form a "fish
RamûÙrez-Ros, Rafael
NEW TECHNOLOGIES ON MATHEMATICAL Rafael de la LLave
Kepler University Linz. Austria Sergei Matveev Chelyabinsk State University 454021 Chelyabinsk. Russia
Seppala, Mika
Rafael Martinelli Pinto Exact Algorithms for Arc and Node Routing ...
vehicles K with capacity Q and a distinguished depot vertex labeled 0. Define. ER = {e ? E|de > 0} as the set of required edges. Let ? be a set of closed.
2011-12 Princeton Global Scholar Rafael Rojas
with an interest in Caribbean and Latin American studies will gain from his expertise, and he will contribute communities, and with Princeton scholars working on Latin America and Mexico through a partnership with one and academic circles will provide graduate students with an interest in Caribbean and Latin American studies
Real Goods Solar San Rafael | Open Energy Information
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Ban Bi Thng cho Bi thng cho nhn vin l g?
vic. VûÙ d: au lng khi b tûˋ ngûÈ, b bng do hû°a cht bn vû o da, b thng trong tai nn xe hi khi i giao hû ng lû m vic: Chi tr nu vic quû§ v khûÇng c hng lng do chn thng ngn cn quû§ v lû m cûÇng vic thûÇng thng trong
Frontiers in Web Data Management Junghoo "John" Cho
of information for many people. Due to its ease and ubiquity, many people first look up pages on the Web when and proliferation indicate, the plentiful information of the World-Wide Web is useful for many people. Users access has more presence on the Web than others, they are discovered and looked at by many people from
Intrusion Detection in SCADA Networks Rafael Ramos Regis Barbosa and Aiko Pras
facilities such as water distribution infrastructures, electricity generation plants and oil refineries need industrial facilities, such as water dis- tribution infrastructures. With the goal of reducing costs industry and government, leading to several efforts to increase secu- rity in these industrial networks
Paris-Sud XI, Universitûˋ de
Path relinking for large-scale global optimization Abraham Duarte Rafael Marti Francisco Gortazar
trajectories connecting elite solutions obtained by heuristic methods (Glover and Laguna 1997). It can in Glover (1989). The approach was then elaborated in greater detail in Glover (1994), as a means
Duarte, Abraham
Enhanced flow of core-softened fluids through nanotubes Jose Rafael Bordin
space. These nano-fluidic features give insights about the behavior of confined isotropic anomalous technology has generated devices with application not only as controlled models for biological systems as nanofilters3 . In this way, the understanding of the nanofluidic inside this devices is of great interest
Barbosa, Marcia C. B.
Protein folding in contact map space Eytan Domany, Rafael Najmanovich and Michele Vendruscolo
assumption of all physical approaches to folding is that there exists some energy function, from which important, we present a method to derive contact energy parameters based on perceptron learning. The energy the proteins in a given database. We show that such an energy function exists if the candidates are produced
Domany, Eytan
Memoria 2011 Biblioteca y Archivo Universidad Autnoma de Madrid Cartoteca "Rafael Mas"
pormenorizados en el Inventario de los Materiales CartogrûÀficos ôÙ 2011, disponible en la web: (http://biblioteca.uam.es/cartoteca/documentos/inventario
CALIFORNIA REPORTING, LLC 52 Longwood Drive, San Rafael, California 94901 (415) 457-4417
) Energy Jobs Act ) CALIFORNIA CLEAN ENERGY JOBS ACT: PROPOSITION 39 DRAFT GUIDELINES Peralta Community-4417 INDEX PAGE Summary of California Clean Energy Jobs Act 6 Elements of the Program 8 Overview of the DRAFT THE CALIFORNIA ENERGY COMMISSION (CEC) In the matter of ) ) Docket No. 13-CCEJA-1 Prop 39-California Clean
Pennington David Ware Nelson R. PeûÝa George Nesbitt, Environmental Design Build, CALHERS, Passive House Group Kurt Hurley, Passive House California Pat Eilert, PG&E Dan Varvais, SPFA Bruce D. Roy Roger Le
Brazilian Tax Affairs
Roberto R. Afonso Rafael Barroso February, 2007 Abstract: InDevelopment and Rafael Barroso is Seniro Advisor at the (like to thank Maria Cristina Barroso, Beatriz Meirelles, Ana
Afonso, Jose Roberto R.; Barroso, Rafael
Influence of catechins on bystander responses in CHO cells induced by alpha-particle irradiation
radicals (Chaudhry, 2006). Catechins, a polyphenolic compound of green tea, are well known as scavengers). (ôÙ)-epigallocatechin gallate (EGCG), which is a major constituent of green tea catechins, is the most active
Yu, K.N.
Variability in the Stability and Productivity of Transfected Genes in Chinese Hamster Ovary (CHO) cells
In the field of biologics production, productivity and stability of the transfected gene of interest are two very important attributes that dictate if a production process is viable. To further understand and improve these ...
Ng, Say Kong
Corollaries to Amdahl's Law for Energy Sangyeun Cho, Member, IEEE Rami G. Melhem, Fellow, IEEE
to minimize the total energy consumption, while the execution time is preserved (i.e., speedup = 1). We show studies the important interaction between parallelization and energy consumption in a parallelizable, and energy consumption and can be directly utilized in energy aware processor resource management. Our
Japan, France Vying for Korea's Nuclear Project By Cho Jin-seo
. Haignere promised privileges in fusion energy businesses and supports for Korea's own fusion energy energy source and considered the next-generation energy of the planet. firstname.lastname@example.com 01,000 Jobs for Poor, Aged Roh's Supporters Launch Fresh 'Piggybank' Drive | | | | Copyrightôˋ Hankooki.com All
HODIFIED ALADDIN LATTICE L2V2 S. Kramer and Y. Cho LS-20 AUS-26
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STA411 Statistical Methods I Worksheet #2 Name:________________________ Prof. Hokwon Cho (Please print)
) Are T and B independent events? Use probability values to explain. _____________ 3. The quality -assurance) ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- Chap. 2 Probability Theory (1) Probability & Basic Rules (2) Counting Rules (3) Conditional Probability
Cho, Hokwon
Proving Termination Properties with mu-term Beatriz Alarcon, Raul Gutierrez, Salvador Lucas, and Rafael Navarro-Marset
Proving Termination Properties with mu-term Beatriz AlarcôÇon, RaôÇul GutiôÇerrez, Salvador Lucas Valencia, Spain Abstract. mu-term is a tool which can be used to verify a number of termination properties of (variants of) Term Rewriting Systems (TRSs): termination of rewriting, termination of innermost rewriting
Lucas, Salvador
SEPARATRIX SPLITTING IN 3D VOLUME-PRESERVING MAPS HECTOR E. LOMELi AND RAFAEL RAMiREZ-ROS
, such structures are called Hill's spherical vortices or spheromaks. We study the splitting of the separatrix under
Fluid velocity fluctuations in a collision of a sphere with a wall J. Rafael Pacheco,1,a)
. Coal-based energy systems such as pulverized coal boilers and gasifiers are of current interest) are scarce. There are notable exceptions, e.g., the case of bubbly liquids at high Reynolds and at low Weber
Pacheco, Jose Rafael
Plasma Anypath Routing in Wireless Mesh Networks Rafael Laufer, Luiz Filipe M. Vieira, Mario Gerla, and Leonard Kleinrock
, and Leonard Kleinrock Computer Science Department Univeristy of California at Los Angeles July 31, 2009
Kleinrock, Leonard
Secretary of Energy Advisory Board Public Meeting Committee Members: John Deutch, Chair; Frances Beinecke, Rafael Bras, Albert Carnesale, Deborah
Broader source: Energy.gov (indexed) [DOE]
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Secretary of Energy Advisory Board Public Meeting Committee Members: John Deutch, Chair; Arun Majumdar, Vice Chair; Rafael Bras; Albert Carnesale;
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarlyEnergyDepartment of Energy U.S. DepartmentCommitment for a Loan Guarantee foratArgonneUSArun
A functional limit theorem for -weakly dependent processes and its applications Jean-Marc Bardeta, Paul Doukhanb, Jose Rafael Leonc
Universidad Central de Venezuela, Escuela de MatemôÇatica., Ap. 47197 Los Chaguaramos, Caracas 1041-A VENEZUELA series, than the strong mixing one. This author aknowledges the program ECOS-NORD of Fonacit, Venezuela
Biblioteca Universitria -Novas aquisies V. 6 N. 07 2014
; MORALEZ, Rafael (Org.). Energia, desenvolvimento e sustentabilidade. 1. ed. Porto Alegre: Zouk, 2014 396 p
Floeter, Sergio Ricardo
Workshop on "Trust in Virtual Teams: Theory and Tools" CSCW 2013 -Feb. 24, San Antonio, Texas, USA
, Brasil ôñ Rafael Prikladnicki, PUCRS, Brasil ôñ Sabrina Marczak, PUCRS, Brasil ôñ Filippo Lanubile
Lanubile, Filippo
Dynamically Optimizing FPGA Applications by Monitoring Temperature and Phillip H. Jones, Young H. Cho, John W. Lockwood
logic density and speed. Large applications with highly pipelined datapaths can ultimately generate more surveillance systems, must adapt to variable am- bient temperatures. Even systems that operate in tightly frequency control mechanism that uses thermal feed- back to adjust the operating speed of a reconfigurable
Lockwood, John W.
Bilateral Kernel-Based Region Detector Woon Cho, Sung-Yeol Kim, Andreas Koschan, and Mongi A. Abidi
. Introduction The detection of covariant regions from one image and its transformed image has been an important on an image of a Siemens star with regular beams as mentioned in [3]. MSER stably extracts a region for each by different methods on the Siemens image containing Gaussian noise (2%) from [3]. Top left to bottom right
Koschan, Andreas
c-Myc degradation induced by DNA damage results in apoptosis of CHO Man-Rong Jiang1
of UV41 cells by TC treatment. Further analysis showed that degradation of the c-Myc protein in TC, MG132, reduced both the degradation of c-Myc and apoptosis in TC-treated UV41 cells. Expression-Myc degradation induced by DNA damage in the presence of TC contributes to induction of apoptosis of UV41 cells
Tian, Weidong
An Underwater Communication and Sensing Testbed in Marina del Rey Andrew Goodney, Young H. Cho, John Heidemann, John Wroclawski
awareness of environmental concerns such as runoff pollution and global climate change, and significant, as government and industry seek to observe, protect, exploit, and control resources underwater. With growing development and deployment. As an initial step, we designed, constructed and deployed two prototype testbed
The characteristics of organicinorganic hybrid low-k thin films by PECVD S.-J. Cho a
conductivity is also important, because of the ever-increasing power density inside chips. Thermal properties of various RF (radio frequency using 13.56 MHz) powers in the range of 20Ù60 W, and then thin films were TransformÙInfrared Spectroscopy), and AFM (Atomic Force Microscopy). The result of FT-IR showed some
Boo, Jin-Hyo
NAGOYA UNIVERSITY GLOBAL 30 INTERNATIONAL PROGRAMSPrinted in March 2014 Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan
include miso-nikomi-udon (Nagoya-style udon noodles with miso soup) and miso-katsu (fried pork cutlets with rich red miso sauce). Nagoya cuisine is also well known for a variety of chicken dishes
Takahashi, Ryo
Application of Interactive Genetic Algorithm to Fashion Design Hee-Su Kim and Sung-Bae Cho
since the Industrial Revolution is on the market economy. Think about clothes market. Before the Industrial Revolution, consumers had to make their own clothes or buy one from very small producers. Naturally they have few choices on it. However the Industrial Revolution enables mass-production, and now
Cho, Sung-Bae
SK-N30(4/8/85) MODIFIED ALADDIN LATTICE N30 S. Kramer and Y. Cho
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr MayAtmosphericNuclear Security Administration the1 -the Mid-Infrared0 ResourceAwards SAGE Awards ,# ,SchoolsNEUTRINOSIS Sign
ARGONNE NATIONAL LABORATORY TO: Y. Cho FROM: W. Praeg SUBJECT: 6 GeV Booster RMS Current
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May JunDatastreamsmmcrcalgovInstrumentsrucLasDeliveredôPNGExperience4AJ01) (See95TI07)Operations2AP-XPSAPS50 -Issue 60ARCSHIGH NATIONAL
Patricia Garnier,1 Rafael Angulo-Jaramillo,2 David A. DiCarlo,3 Tim W. J. Bauters,4 Christophe J. G. Darnault,4 Tammo S. Steenhuis,4
was minimized by rounding off the corners with a smooth but hard sealant and by lubricating the walls with an oil. Moreover, to minimize friction, unlike the experiment of Smiles and Colombera [1975
Walter, M.Todd
A Trust Model for Multiagent Recommendations Fabiana Lorenzi1,2, Gabriel Baldo2, Rafael Costa2, Mara Abel1, Ana Bazzan1, Francesco Ricci3
.501-970 Porto Alegre, RS, Brasil 2Universidade Luterana do Brasil Av. Farroupilha, 8001 Canoas, RS, Brasil 3Free
Ricci, Francesco
Secretary of Energy Advisory Board Public Meeting Committee Members: John Deutch, Co-Chair; Frances Beinecke, Rafael Bras, Albert Carnesale, John
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of Inspector GeneralDepartment of Energyof the Americas | Department ofofDelivered | DepartmentArgonneJohn
Secretary of Energy Advisory Board Public Meeting Committee Members: John Deutch, Co-Chair; Frances Beinecke, Rafael Bras, Albert Carnesale, Shirley
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of Inspector GeneralDepartment of Energyof the Americas | Department ofofDelivered |
Secretary of Energy Advisory Board Public Meeting Committee Members: John Deutch, Co-Chair; Persis Drell, Co-Chair; Rafael Bras; Albert Carnesale; Shirley
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "ofEarly Career Scientists' Research |Regulation Services2014NeedCollegeof Energy WASHINGTON,3 Summary
ESD Working Paper Series ESD-WP-2011-01 January 2011
Europe: An Example of Social Innovation Rafael MaraûÝû°n-Abreu Massachusetts Institute of Technology 77 in Southern Europe: An Example of Social Innovation Rafael MaraûÝû°n
de Weck, Olivier L.
E-Print Network 3.0 - antiviral del extracto Sample Search Results
Profesionales), Richard Rivas (Coordinador de Ingeniera Elctrica), Rafael Urbina (en representacin ... Source: Vsquez, Carlos - Departamento de Fsica,...
PEESOS: A Web Tool for Planning and Execution of Experiments in Service Oriented Systems
. Nunes , Luis H. V. Nakamura , Bruno T. Kuehne , Edvard M. de Oliveira , Rafael M. de O. Libardi , Lucas
Reiff-Marganiec, Stephan
Power-Factor and Torque Calculation with Consideration of Cross Saturation of the Interior Permanent Magnet Synchronous Motor with
motor of a hybrid electric vehicle. I. INTRODUCTION The interior permanent magnet synchronous motor for application in a hybrid electric vehicle. The BFE structure enables the motor to control the magnitude Permanent Magnet Synchronous Motor with Brushless Field Excitation Seong Taek Lee1,2 , Timothy A. Burress1
Tolbert, Leon M.
A DDS and PLL-based X-band FMCW Radar System
such as level meter of liquid tanks, collision avoidance, and other short range measurement applications [1A DDS and PLL-based X-band FMCW Radar System Yun-Taek Im, Jee-Hoon Lee, and Seong-Ook Park source, and the PLL is controlled by it. The bandwidth and the sweep time of the FMCW radar system
Park, Seong-Ook
Published Research Reports Advanced LED Warning Signs for Rural
Review of Driver Gap Acceptance and Rejection Behavior at Rural Thru-Stop Intersections in the US ôÙ Data by Renewable Energy Taek Mu Kwon and Ryan Weidemann MnDOT 2011-04 Usability Evaluation of a Smart Phone- based of the Twin Cities Xinyu (Jason) Cao, Frank Douma, Fay Cleaveland, and Zhiyi Xu CTS 10-12 Development of a Low
Minnesota, University of
Toplaceyourmealorderpleasedial MEAL(ext.6325)
/Stuffing&Gravy(1CHO) Macaroni&Cheese(2CHO) Pasta:RotiniorWholeWheatPennew/yourchoiceof: GarlicSaladRoastBeef EggSalad PeanutButter&Jelly BreadsWhite,Wheat,Rye,(eachslice=1CHO) KaiserRoll(2CHO) ExtrasSubstitute TurkeySausage FrenchToast(1CHO)Pancakes(2CHO) CreamofWheat(1CHO)Oatmeal(2CHO) EnglishMuffin(1.5CHO
Oliver, Douglas L.
Toplaceyourmealorder,pleasedial MEAL(ext.6325)
) Meatloaf(1CHO) Turkeyw/Stuffing&Gravy(1CHO) TurkeyPotPie(2CHO) Macaroni&Cheese(2CHO) Pasta:RotiniorWholeWheatMeatsCheeses TunaSaladTurkeyAmerican ChickenSaladRoastBeefSwiss EggSaladHamProvolone BreadsWhite,Wheat) BreakfastBurrito:Eggs,Cheese,SalsainaWrap(1CHO) FrenchToast(1CHO) Pancakes(2CHO) CreamofWheat(1CHO
Oblivious Routing in On-Chip Bandwidth-Adaptive Myong Hyon Cho, Mieszko Lis, Keun Sup Shim, Michel Kinsy, Tina Wen and Srinivas Devadas
link, and this reconfiguration can be done very rapidly in response to changing traffic demands. We Massachusetts Institute of Technology Cambridge, MA {mhcho, mieszko, ksshim, mkinsy, tinaw, devadas, especially when bandwidth demands of flows vary with time, because routes are not adjusted for different
Gifford, David K.
Micro artificial muscle fiber using NiTi spring for soft robotics Sangbae Kim, Elliot Hawkes, Kyujin Cho, Matthew Jolda, Joe Foley and Robert Wood
from shape memory alloy (NiTi) coiled springs. An enhanced spring NiTi model describes the combination of micro-coil spring, we present a novel mesh-worm prototype that utilizes bio-inspired antagonistic structure alteration, NiTi can be restructured into coil springs. Chang et al.[1], discuss the numerous
Wood, Robert
11/11/2002 1AVS 49th Int'l Symp. MS-MoA7 (Oct. 29, 2002) -Cho Dynamic Simulation and Optimization
Research with collaboration and support from the U. Arizona NSF/SRC Center for Environmentally Benign maintenance Preventive maintenance Equipment failures Equipment failures Factory, subfactory, & tool logistics Priority - "Hard" constraint Speed, power, density, yield, reliability Technology Performance #12
Rubloff, Gary W.
Exploiting Diversity of Neural Ensembles with Speciated Evolution Seung-Ik Lee, Joon-Hyun Ahn, and Sung-Bae Cho
and is mod- ified using speciation technique. All fitnesses calculated, selection is conducted. Genetic operators, crossover and mutation, are applied to the selected individuals to produce next generation
Panegyrics in Honor of Sakya Pandita (Cho rje sa skya pan+Di ta la bod kyi mkhas pa rnams kyis bstod pa)
of the ocean of Sciences, Seized with the treasure island of Sermon, With reputation decorating the ears of all, (Thou) Sakyapa wonderous object of praise. '2. By knowledge (Thou) seest the Truth of all Wisdom, Out of love (Thou) entertainest the living...
Tulku, Mynak R
) GrilledChicken ChickenMarsala(0.5CHO) ChickenParmesan Macaroni&Cheese(2CHO) Pasta:RotiniorWholeWheatSaladTurkeySwiss ChickenSaladRoastBeef PeanutButter&DietJelly BreadsWhite,Wheat,Rye(eachslice=1CHO) KaiserRoll(2CHOBoiledEgg EggSubstitute TurkeySausage FrenchToast(1CHO) Pancakes(2CHO) CreamofWheat(1CHO) Oatmeal(2CHO
Mapa GlobCover 2009. European Space Agency (ESA). www.esa.int Ciudad Universitaria de Cantoblanco 28049 Madrid
.uam.es/cartoteca/default.html Cartoteca "Rafael Mas" INVENTARIO DE LOS MATERIALES CARTOGRûFICOS 2010 #12;UAM. Cartoteca "Rafael Mas". Inventario, 2010 2 La CARTOTECA RAFAEL MAS es una biblioteca especializada en cuanto a las caracterûÙsticas". Inventario, 2010 3 El BoletûÙn Meteorolû°gico Diario, editado por el Instituto Nacional de MeteorologûÙa, fue
Three Essays on Financial Economics
Journal of Financial Economics, February 2003, 67 (2), 217Journal of Financial Economics, March 2008, 87 (3), 706739.International Finance and Economics, 2008. Schiozer, Rafael
Qu, Haonan
Green Buildings in Green Cities: Integrating Energy Efficiency into the Real Estate Industry
Costs and Financial Benefits of Green Buildings A Report toEvidence on the Green Building Rent and Price Premium, (Properties. San Rafael: Green Building Finance Consortium.
Bardhan, Ashok; Kroll, Cynthia A.
-----------------------------------------------------------------------------------------------------------------ôñ 57 Rafael W. Rodriguez The Submari ne LandsIide of 1980 off Northern Ca Zone _____________________________ 125 James V. Gardner Abstracts of selected papers submitted
affects body weight: Topics by E-print Network
weight perceptions may be influ- enced by food habits and food environments, nutritional knowledge, cultural norms and expectations and mass media Mikolajczyk, Rafael T; Maxwell,...
E-Print Network 3.0 - ao cultural na Sample Search Results
DO SUL INSTITUTO DE INFORM ' Summary: -orientador Porto Alegre, outubro de 1994. 12; 2 CIP - CATALOGA C AO NA PUBLICA C AO Bordini, Rafael Heitor... Bandeira da Silva)...
aceitera sobre las: Topics by E-print Network
Sobre algunas Granero, Rafael 6 V SEMINARIO HISPANO-ARGENTINO: Los discursos sobre la Ciencia y las Nuevas Tecnologas en la Sociedad del Conocimiento Engineering Websites Summary:...
anatomico sobre las: Topics by E-print Network
apuntes sobre las: Topics by E-print Network
Sobre algunas Granero, Rafael 9 V SEMINARIO HISPANO-ARGENTINO: Los discursos sobre la Ciencia y las Nuevas Tecnologas en la Sociedad del Conocimiento Engineering Websites Summary:...
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Computer Technologies and Information Sciences 32 A Semantic Navigation Model for Video Games Leonard van Driel and Rafael Bidarra Summary: . In this paper we develop a generic...
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de Pacotes IP Rafael P... ao de rota para identificar o verdadeiro atacante. Neste artigo, e proposto um procedimento alternativo... procedimento alternativo de...
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con frecuencia aparecan algunas reflexiones sobre la importancia y la... Sucesor, 1894, p. 5. 11 Rafael Aguirre Cinta, Lecciones de historia general de Mxico, Mxico, Sociedad...
aterro para energia: Topics by E-print Network
1. Introducci Granero, Rafael 39 Portugal lidera consrcio envolvido na produo de "energia limpa, segura e abundante" Engineering Websites Summary: ) - A produo de...
Toward a Genealogy of Mestizaje: Rethinking Race in Colonial Mexico
pºblica en la Nueva Espaþa. Mexico City: Editorial Progreso,Pontifical University of Mexico. Trans. Minnie Lee Barrettand trans. Rafael Tena. Mexico City: Consejo Nacional para
Nemser, Daniel
Cdric Audebert (2011), Rgionalisme et migrations dans la Carabe , in Eric Dubesset et Rafael Lucas (dir.) La Carabe dans la mondialisation : Quelles dynamiques rgionalistes ?, Paris : L'Harmattan, pp. 23-37
Lucas (dir.) La Caraû₤be dans la mondialisation : Quelles dynamiques rûˋgionalistes ?, Paris : L'Harmattan mondialisation : Quelles dynamiques rûˋgionalistes ?, Paris : L'Harmattan, pp. 23-37 2 1. L'identitûˋ caribûˋenne et
Rafael Reif has served as the 17th President of the Massachusetts Institute of Technology (MIT) since July 2012. In his inaugural speech, Dr. Reif outlined the threats and opportunities presented by the sudden rise of
by the sudden rise of credible, low-cost online learning alternatives and challenged MIT to use the campus, Dr. Reif also launched an environment initiative to drive progress towards solutions around-dimensional integrated circuit technologies and on environmentally benign microelectronics fabrication. In 2004, he
Reif, Rafael
BREAKFASTMenu1+3 Yourmenuwillbecorrectedaccordingtothe
Krispies SpecialK Cheerios Oatmeal CreamofWheat RaisinBran(2CHO) BreakfastBreads (1CHO) Blueberry)TurkeyPotPie(2CHO) Turkeyw/Stuffing&Gravy(1CHO) Macaroni&Cheese(2CHO) Pasta:RotiniorWholeWheat/LowfatItalian/LowfatFrench) DESSERTS:(Limit2,1mustbefruit)(1 CHOEACH) AngelFoodCakeDietGelatin(free) Diet
BREAKFAST MENU 5 Yourmenuwillbecorrectedaccordingtothe
Krispies SpecialKCheerios CreamofWheat Oatmeal BreakfastBreads BlueberryMiniMuffin (1CHO) CornMiniMuffin(1CHO) ChickenMarsala(1CHO) Meatloaf(1CHO)PotRoast Pasta:RotiniorWholeWheatPenne w,1mustbefruit)(Each 1CHO) AngelFoodCake FreshFruit:Apple,Grapes,Pineapple, CannedFruit:Peaches,Pears, Applesauce
SPECIAL ISSUE PATTERNS & PHENOTYPES Identification of Genes Expressed
in the Developing Peripheral Margin of the Optic Cup Jeffrey M. Trimarchi, Seo-Hee Cho, and Constance L. Cepko. Jeffrey M. Trimarchi and Seo-Hee Cho contributed equally to this work. Seo-Hee Cho's present address
Tabin, Cliff
Dynamics of fluid-filled gelatin cracks www.math.utwente.nl/bokhoveo/
of relevance to geology and industry. Geology: magma dike and conduit formation in San Rafael Volcanic field, and Shimabara-Beppu Graben: dike-rock-fault interactions. Industry: enhanced oil-recovery, CO2-sequestration, mining: dike-rock-tunnel interactions? #12;Geology: San Rafael Volcanic fields, Utah Volcanic plumbing
Al Hanbali, Ahmad
Transcriptome of a Nitrosomonas europaea mutant with a disrupted nitrite reductase gene (nirK)
2005. New CHO ET AL. A PPL . E NVIRON . M ICROBIOL .P value of ?0.1. CHO ET AL. A PPL . E NVIRON . M ICROBIOL .
Cho, CMH; Yan, T F; Liu, X D; Wu, L Y; Zhou, J Z; Stein, L Y
Burrito:Eggs,Cheese, Salsainawrap (2CHO) TurkeySausage Cereals(1CHOEACH) RiceKrispies SpecialK Cheerios Oatmeal CreamofWheatCHO) Turkeyw/Stuffing&Gravy(2CHO) Macaroni&Cheese(2CHO) Pasta:RotiniorWholeWheatPenne w (Oil&Vinegar/LowfatItalian/LowfatFrench) DESSERTS:(Limit2,1mustbefruit)(1 CHOEACH) Angel
Dynamic evolution of plant mitochondrial genomes: Mobile genes and introns and highly variable
variable mutation rates Jeffrey D. Palmer*, Keith L. Adams, Yangrae Cho , Christopher L. Parkinson , Yin
Parkinson, Christopher L.
Krispies SpecialK Cheerios Oatmeal CreamofWheat RaisinBran(2CHO) BreakfastBreads (1CHO) Blueberry)GrilledChicken Meatloaf(1CHO)TurkeyPotPie(2CHO) Macaroni&Cheese(2CHO)PotRoast Pasta:RotiniorWholeWheat/LowfatItalian/LowfatFrench) DESSERTS:(Limit2,1mustbefruit)(1 CHOEACH) AngelFoodCakeDietGelatin(free) Diet
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CHOEach) RiceKrispies SpecialK Cheerios CreamofWheat Oatmeal BreakfastBreads BlueberryMiniMuffin (1/Stuffing&Gravy(2CHO) Macaroni&Cheese(2CHO) ChickenMarsala(1CHO) Meatloaf(1CHO) GrilledChickenPotRoast Pasta:RotiniorWholeWheatGreens (Oil&Vinegar/LowfatItalian/ LowfatFrench) DESSERTS:(Limit2,1mustbefruit) (Each1CHO) Angel
ATA DA TRECENTSIMA TRIGSIMA NONA REUNIO DO CONSELHO UNIVERSITRIO (CONSUNI), realizada aos quatro dias do ms de julho do ano de
GOMES (SER - Suplente), EDUARDO RENNû? ZANATA (IL), RAFAEL HOLANDA BARROSO (IPOL), Jû?LIA H. CARRANZA (IdA ôÙ Suplente), TONY GILIOTTI BEZERRA (IREL), EMANUEL HOLANDA BARROSO (Adm. Agro. ôÙ Suplente), EDEMILSON CRUZ
Maier, Rudolf Richard
aguas produzidas utilizando: Topics by E-print Network
atmosfera reativas, (more) Rafael Domingues Della Pace 2011-01-01 102 Using Renewable Energy to Pump Water (Spanish) Texas A&M University - TxSpace Summary: Utilizando energ?a...
Design of Optimal Experiments for Parameter Estimation of Microalgae
. Keywords: biofuel, microalgae, model calibration, optimal control, optimal experiment design 1 candidate for biofuel production in large scale cultivation is a difficult task since microalgae growthDesign of Optimal Experiments for Parameter Estimation of Microalgae Growth Models Rafael Mu
Paris-Sud XI, UniversitÕ de
innovative research fa l l 2 0 0 8
in research sponsored by numerous federal agencies. With his long history of support from the Air Force by the students of Electrical and Computer Engineering Professor Rafael Fierro, a new collaborator of Professor
New Mexico, University of
E-Print Network 3.0 - aging eye role Sample Search Results
across eyes Susana Marcos a,b, *, Stephen A. Burns a , Pedro M. Prieto a... ,c , Rafael Navarro b , Begona Baraibar b a Schepens Eye Research Institute, 20 Staniford Street,...
RadiografÚa de muestras de suelo de la Laguna de Medina #12;2 #12;3 Investigador responsable: Andy J. Green Equipo de redacciµn: Hugues Lefranc, Andy J. Green, Rafael Mateo, Mark Taggart y Jordi Figuerola
Figuerola, Jordi
responsable: Andy J. Green Equipo de redacciµn: Andy J. Green, Rafael Mateo, Hugues Lefranc, Jordi Figuerola y .........................................................................................4 2.- Muestreo de plomo en suelos de marismas y lagunas andaluzas .....................8 2
Evaluation of Economic Impact of Three-Dimensional Modeling in Precast Concrete Engineering
Evaluation of Economic Impact of Three-Dimensional Modeling in Precast Concrete Engineering Rafael (IT); Concrete, precast; Economic factors; Three-dimensional models. Introduction "The application to this; but the funda- mental reason undoubtedly was economic." (Mitchell 1977). Intuitive assessments
Sacks, Rafael
Adaptive control for optimizing microalgae production
Adaptive control for optimizing microalgae production Francis Mairet Rafael Mu for light-limited microalgae culture. This controller regulates the light absorption factor, defined productivity under day-night cycles. Keywords: Nonlinear controller, Microalgae, Optimization, Biomass
Metadata of the chapter that will be visualized online Chapter Title Assessing Habitat Fragmentation Effects on Primates: The Importance of
, Canada, H3A 2T7 Author Family Name Reyna-Hurtado Particle Given Name Rafael Suffix Organization ECOSUR-Campeche, Avenida Rancho s/n Address Poligono 2, Lerma, 24500El, Campeche, Mexico Author Family Name Fahrig Particle
Arroyo RodrûÙguez, VûÙctor
California: SunShot-Supported Technology Maximizes Taxpayer's...
Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site
installation time in half, making it faster, easier, and cheaper for more Americans to go solar. Location San Rafael, California Partner Zep Solar EERE Investment 100,000 Clean...
Cazadores-Recolectores Tempranos Y Supervivencia De Fauna Del Pleistoceno (Equus Sp. Y Glyptodon Sp.) Durante El Holoceno Temprano En La Frontera Uruguay-Brasil [Portuguese
Direcciµn RÚo Grande do Sul (Brasil). ComunicaÓÐo Museu deN¤ 5. RÚo Grande do Sul (Brasil) A FormaÓÐo Touro Passo, Seuen la Frontera UrUgUay-Brasil Rafael SuÃrez1 y Guaciara m.
SuÃrez, Rafael; Santos, Guaciara M.
autocompensating quantum cryptography: Topics by E-print Network
Summary: Towards Non-Black-Box Lower Bounds in Cryptography Rafael Pass , Wei-Lung Dustin Tseng on the impossibility of basing cryptography on NP hardness (these works also...
Programa y Problemas de Ecuaciones Diferenciales Equipo docente de Ecuaciones Diferenciales
Ecuaciones Lineales 3 Sistemas Lineales 15 Sistemas No Lineales 25 Modelos 31 EDPs 41 iii #12;#12;Prefacio ôÇutil y no contenga demasiados errores. Cualquier comentario constructivo serôÇa bienvenido. Rafael Ram
Ecuaciones Lineales 3 Sistemas Lineales 11 Sistemas No Lineales 17 Modelos 21 EDPs 29 iii #12;#12;Prefacio comentario constructivo serôÇa bienvenido. Rafael RamôÇirez Ros Barcelona, a 28 de junio de 2010 Aprende
Casanellas, Marta
errores. Cualquier comentario constructivo serôÇa bienvenido. Rafael RamôÇirez Ros Barcelona, a 12 de abril] Nociones y resultados bôÇasicos. Sistemas lineales. Sistemas no lineales. Modelos 3. Ecuaciones en Derivadas
antebrachial growth deformity: Topics by E-print Network
boost generator as the corner transfer matrix is briefly discussed. Cesar Gomez; Rafael Hernandez 2007-03-23 35 Deformation in Phase Space Mathematical Physics (arXiv) Summary:...
Forthcoming: Review of Economics and Statistics Superior Forecasts of the U.S. Unemployment Rate
and the editor Jim Stock for their thoughtful comments and helpful suggestions. We also appreciate, Hooker and Oswald (1998, henceforth "CHO"). Both MZTT and CHO take to heart Ramsey's (1996) admonition
Perloff, Jeffrey M.
Surface Optomechanics: Mechanical Whispering Gallery Modes in Microspheres
. , 2010 (In Review) #12;Qiang Lin, et al., PRL 2009 Adrian Cho PRL, 2009. Tomes, et al., PRL, 2009. Carmon, et al., PRL 2005 Figure Credit: Adrian Cho, Science 2009-2010 (2009). PRL, 2005. #12;WGMs schematic
Carmon, Tal
Burrito:Eggs,Cheese,Salsaina wrap (2CHO) TurkeySausage Cereals(1CHOEACH) RiceKrispies SpecialK Cheerios Oatmeal CreamofWheat) TurkeyPotPie(2CHO) Turkeyw/Stuffing&Gravy(2CHO) Macaroni&Cheese(2CHO) Pasta:RotiniorWholeWheatPenne wSaladw/Cucumbers&OrganicField Greens (Oil&Vinegar/LowfatItalian/LowfatFrench) DESSERTS:(Limit2,1mustbefruit)(1 CHOEACH) Angel
Independent Nonframeshift Deletions in the MC1R Gene Are Not Associated with
Taikyu High School, 1985 Yuasa-cho, Arida-gun, Wakayama 643-0004, Japan (Hosoda); Laboratory of Animal
Campbell, Kevin L.
Evolutionary and biogeographic history of weasel-like carnivorans (Musteloidea) q Jun J. Sato a
, 1985 Yuasa-cho, Arida-gun, Wakayama 643-0004, Japan g Department of Biological Sciences, University
.051786/2013-67 INSTRUMENTO: Convûˆnio PARTûCIPES: Universidade Federal Fluminense ôÙ UFF e Barroso Fontelles, Barcellos-Reitor de GraduaûÏûÈo da Universidade Federal Fluminense ôÙ UFF e RAFAEL BARROSO FONTELLES, Sû°cio do Escritû°rio de Advocacia - Barroso Fontelles, Barcellos, MendonûÏa e Advogados. Publique-se LEILA MARIA PEREIRA
Souza, Max O.
Highlighted article Metal levels in the bones and livers of globally threatened marbled teal
ô´gen 18A, SE-752 36 Uppsala, Sweden d Institute of Maths, Natural and Computer Science, University of Ga and white-headed duck from El Hondo, Spain Mark A. Taggart a,e,û?, Andy J. Green b , Rafael Mateo a , Fredrik). Further, the wetland has experienced periodic episodes where avian mortality has in- creased markedly
Green, Andy J.
Prognostics of PEM fuel cell in a particle filtering framework Marine Jouin
Prognostics of PEM fuel cell in a particle filtering framework Marine Jouin , Rafael email@example.com Abstract Proton Exchange Membrane Fuel Cells (PEMFC) suffer from a limited lifespan, which impedes of the proposed approach. Keywords: Proton exchange membrane (PEM) fuel cell, Prognostics, Remaining useful life
JOURNALDE PHYSIQUE IV Colloque C7, supplBmentau Journalde Physique 111,Volume 4,juillet 1994
-sectionalthermal-waveimage of the thermal diffusivity of the chosen slice [2]. The one-dimensional ray-optic based reconstruction technique(r) is the thermal diffusivity and o is the angular frequency of the modulation of thelaser beam intensity. F [4-61: (1) On leave from Rafael, P.O. Box 2250, Haifa 31021, Israel Article published online by EDP
2012 Service Awards Reception Havemeyer House
-Ihne, Timothy Osborne, Earl Ritchie, Rafael Rodriguez, James Smyth, Janet Stern, Sally Wilson 30 Year, Artemio Taclob, Michael Unger, James Woodley, Louis Yacopino 10 Year Anniversaries Therese Biagi, Bonnie, James Morley, Lysandra Perez-Strumolo, Laura Plessner, Richard Russo, William Schwenzer, Ruma Sen
Rainforth, Emma C.
State of California E-Mail M e m o r a n d u m
of the 2013-2014 Sustainability Advisory Committee I am pleased to endorse the nominations and hereby appoint, the following individuals to membership on the Sustainability Advisory Committee for the period indicated. NAME Christine Theodoropoulos 2013-2015 Adrienne Greve Dean, Architecture & Env. Design Rafael Jimenez
Sze, Lawrence
Les groupes financiers et industriels au service du roi -Espagne Fin XVIIe -dbut XVIIIe sicle
'une part de la puissance publique y avaient massivement recours, les ûˋvûˆques, les seigneurs, les villes importance au XVIIIe siû´cle. Voir, entre autres: Torres SûÀnchez (Rafael), "El gran negocio de la ûˋpoca, la
Chronic polyarthritis associated to Cercopithi?laria bainae infection in a dog
Rafael A.N. Ramos Cinzia Cantacessi Maria Stefania Latrofa Gabriella Cancrini Domenico Otranto PII: S0304-4017(14)00374-4 DOI: http://dx.doi.org/doi:10.1016/j.vetpar.2014.06.027 Reference: VETPAR 7305 To appear in: Veterinary Parasitology Received date...
Gabrielli, Simona; Giannelli, Alessio; Brianti, Emanuele; Dantas-Torres, Filipe; Bufalini, Massimiliano; Fraulo, Maurizio; La Torre, Francesco; Ramos, Rafael A.N.; Cantacessi, Cinzia; Latrofa, Maria Stefania; Cancrini, Gabriella; Otranto, Domenico
http://tti.tamu.edu Saving Lives, Time and Resources
: ñ partnering with public and private information providers to help companies understand the costs and benefits Intelligent Transportation Research and the Coaliciµn Empresarial Pro Libre Comercio (CELC) conducted a border information about TTI's Center for International Intelligent Transportation Research: Rafael Aldrete CIITR
Consejo Asesor del Decanato de Estudios Tecnolgicos Acta 08-2011 Pg. 1 de 5 UNIVERSIDAD SIMON BOLIVAR
Organizaciµn empresarial), Armando JimÕnez (Coordinador de Comercio Exterior), MarÚa FÃtima Pinho (Coordinadora de la Carrera TecnologÚa ElÕctrica), Rafael Crespo (Responsable de la Carrera Comercio Exterior Actas Anteriores. 3. Informe del Decano. 4. Casos de estudiantes 5. Varios. 1. Consideraciµn del Orden
VÃsquez, Carlos
Consejo Asesor del Decanato de Estudios Tecnolgicos Acta 04-2011 Pg. 1 de 4 UNIVERSIDAD SIMON BOLIVAR
(Responsable de la Carrera TecnologÚa ElÕctrica), Rafael Crespo (Responsable de la Carrera Comercio Exterior. Consideraciµn del Orden del DÚa. 2. Lectura y Aprobaciµn de Actas Anteriores. 3. Informe del Decano. 4. Casos de Reglamento del Decanato de Estudios Tecnolµgicos. 2. Informe del Decano Recuerda a los coordinadores la
1106 IEEE TRANSACTIONS ON FUZZY SYSTEMS, VOL. 17, NO. 5, OCTOBER 2009 A Multiobjective Evolutionary Approach to
EAs. Finally, a data-complexity measure, which is typically used in pattern recognition to evaluate1106 IEEE TRANSACTIONS ON FUZZY SYSTEMS, VOL. 17, NO. 5, OCTOBER 2009 A Multiobjective Evolutionary Approach to Concurrently Learn Rule and Data Bases of Linguistic Fuzzy-Rule-Based Systems Rafael Alcal
Granada, Universidad de
Short communication On the use of the Radon Transform in studying nearshore wave dynamics
shallow water domain, the celerity of short waves is a key kinematic variable to describe energy fluxesShort communication On the use of the Radon Transform in studying nearshore wave dynamics Rafael 23 June 2014 Available online xxxx Keywords: Surf zone Wave transformation Wave propagation
Congreso de Metodos Numericos en Ingenieria 2005 Granada, 4 a 7 de julio, 2005
Congreso de MôÇetodos NumôÇericos en IngenierôÇia 2005 Granada, 4 a 7 de julio, 2005 c SEMNI, Espa~na, 2005 CôÇALCULO DEL VECTOR PAGERANK DE GOOGLE MEDIANTE EL MôÇETODO ADITIVO DE SCHWARZ Rafael Bru Markov, MôÇetodos iterativos de Schwarz, DescomposiciôÇon de dominios. Resumen. El vector Page
Pedroche, Francisco
The San Francisco/Oakland Bay Bridge Will be Partially Closed Presidents' Day Weekend 2012
/or alternate bridges: Golden Gate, Richmond-San Rafael, San Mateo-Hayward, Dumbarton BART (BAY AREA RAPIDThe San Francisco/Oakland Bay Bridge Will be Partially Closed Presidents' Day Weekend 2012 In order to complete an essential step in the construction of the new Bay Bridge, the WESTBOUND DECK of the Bay Bridge
Hellerstein, Joseph M.
Seropositivity and Risk Factors Associated with Toxoplasma gondii Infection in Wild Birds from Spain
Spain Oscar CabezoôÇ n1 , Ignacio GarciôÇa-Bocanegra2 , Rafael Molina-LoôÇ pez3 , Ignasi Marco1 , Juan M Veterinaria, Universitat Auto`noma de Barcelona, Bellaterra, Spain, 2 Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de CoôÇrdoba, CoôÇrdoba, Spain, 3 Centre de Fauna Salvatge de Torreferrussa
Richner, Heinz
not used to address problems in the realm of optimization as we view it today. More recently, Glover (1977;2 RAFAEL MARTôÇI, MAURICIO G.C. RESENDE, AND CELSO C. RIBEIRO this framework are given in (Glover (1986), Glover (1989), and Glover (2000)) ad- dressing controlled randomization, learning strategies, induced
Fisher, Kathleen
not used to address problems in the realm of optimization as we view it today. More recently, Glover (1977 #12;2 RAFAEL MARTôÇI, MAURICIO G.C. RESENDE, AND CELSO C. RIBEIRO framework are given in Glover (1986), Glover (1989), and Glover (2000), addressing controlled randomization, learning strategies, induced
Resende, Mauricio G. C.
Yoram Rubin notes made at the Hydrology Section Award Ceremony, December 2005, San Francisco
Yoram Rubin notes made at the Hydrology Section Award Ceremony, December 2005, San Francisco Dear Hydrology Section president Rafael Bras and President-elect George Hornberger, members of the hydrology of the breadth of possibilities that hydrology represents overall. Hence, I was grateful to be reminded, during
Rubin, Yoram
Revue de presse hebdomadaire 01-07 octobre 2012
dos aûÝos de trabajo. La paradoja de Fortuna (por Rafael Mûˋndez) : Esta es la historia del publo de Fortuna , en Murica. Un ejemplo de la caûÙda del imperio del ladrillo. PolûÙticos y promotores empeûÝados en
Rennes, Universitûˋ de
crop science, vol. 53, julyaugust 2013 www.crops.org 1 Alfalfa is widely cultivated throughout the world and is the
crop science, vol. 53, julyôÙaugust 2013 www.crops.org 1 ReseaRch Alfalfa is widely cultivated are a severe problem for alfalfa pro- duction in many parts of the world, including the southeastern United of Two Transgenes for Aluminum Tolerance in Alfalfa Rafael Reyno, Dong-Man Khu, Maria J. Monteros, Joseph
Parrott, Wayne
ORIGINAL PAPER Use of grit supplements by waterbirds: an experimental
with food particles causes Pb poisoning in a large number of waterbirds, this being one of the main causes ingest Pb shot pellets as grit or inadvertently with food particles and thus suffer from Pb poisoning to reduce lead poisoning Monica Martinez-Haro & Andy J. Green & Pelayo Acevedo & Rafael Mateo Received: 17
Multicriteria Genetic Tuning for the Optimization and Control of HVAC Systems
Multicriteria Genetic Tuning for the Optimization and Control of HVAC Systems Rafael Alcala1, Jose of genetic algorithms for the optimization and control of Heating, Ventilating and Air Conditioning (HVAC of these systems. An optimum operation of the HVAC systems is a necessary condition for mini- mizing energy
Casillas Barranquero, Jorge
Ray Tracing JELLO Brand Paul S. Heckbert
Ray Tracing JELLôÙO ôÛ Brand Gelatin Paul S. Heckbert Dessert Foods Division Pixar San Rafael, CA ABSTRACT Ray tracing has established itself in recent years as the most general image synthesis algorithm for ray tracing JellôÙO ôÛ brand gelatin. We believe the method may have application to other brands
Treuille, Adrien
Turno 0 03-12-2012 12:00 512 Estudiantes 01-34169 Julio E Mora B
Centeno 05-39011 Jorge G Urbina Bermudez 05-39039 Carlos Raul Verde Aguirre 05-39073 Alan R Zambrano R Hernandez Villegas 06-39727 Luis D Herrera Zambrano 06-39752 Briseida Liliana Jara Arias 06 Arraiz #12;06-40037 Rafael H Paytuvi Egui 06-40045 Daniela M Peralta Lazo 06-40072 Linda R Perez
VûÀsquez, Carlos
Key ornamental innovations facilitate diversification in an avian radiation
Key ornamental innovations facilitate diversification in an avian radiation Rafael Maiaa,1 , Dustin novel ways of interacting with the en- vironment (key innovations) play a fundamental role in promoting evolution of orna- mental traits. Because selection can operate only on existing vari- ation, the tendency
Rubenstein, Dustin R.
Abstract--Nowadays, there are huge ranges of energy market participants. Commercial success of this area actor
Department, 18 Unirii Av., Targoviste, Romania (e- mail: firstname.lastname@example.com). Florin Dragomir and Electrical Engineering Department, 18 Unirii Av., Targoviste, Romania (e-mail: drg_ email@example.com). Rafael Av., Targoviste, Romania (e-mail: email@example.com). state of the analyzed system the closest
ADVANCED DIRECT MANIPULATION OF FEATURE MODELS Rafael Bidarra, Alex Noort Faculty of Electrical validity maintenance. In particular, it offers a powerful combination of various 3D handles for real and are functionally signifi- cant for some product life-cycle phase" (Bidarra and Bronsvoort, 2000). In contrast
Bidarra, Rafael
Services in Game Worlds: A Semantic Approach to Improve Object Interaction
Tutenel, and Rafael Bidarra Computer Graphics Group Delft University of Technology, The Netherlands Jassin in games are still useless, being there for decoration purposes only. Only few objects, which are crucial], several objects, which look useless at first sight, can be combined to create a functional object: a full
| London Mathematical Society Nonlinearity Nonlinearity 27 (2014) 10031028 doi:10.1088/0951-7715/27/5/1003
I, Universitat Polit`ecnica de Catalunya, Diagonal 647, 08028 Barcelona, Spain E-mail: Rafael.Ramirez@upc the caustic types, the winding numbers and the ellipsoids of such minimal periodic trajectories. We also trajectories, so their study is the first task. There exist two remarkable results concerning periodic billiard
PPA Budget Planning: August 26, 2010 Page 1 David B. MacFarlane, William Wisniewski, and
PPA Budget Planning: August 26, 2010 Page 1 David B. MacFarlane, William Wisniewski, and Rafael Alva August 26, 2010 FY11 Research Plan Goal Setting and Budgets #12;PPA Budget Planning: August 26, 2010 Page 2 Content ñ Desired outcomes for the planning and budget exercise ñ Background and key
Wechsler, Risa H.
Darwinian shortfalls in biodiversity conservation
Darwinian shortfalls in biodiversity conservation JoseôÇ Alexandre F. Diniz-Filho1 , Rafael D, and biodiversity conservation Species are considered indisputable units in conservation and biodiversity analyses in conservation planning and biodiversity analyses has been continuously dis- cussed [3,4]. However, species
Mooers, Arne
PAN@FIRE 2013: Overview of the Cross-Language !ndian News
PAN@FIRE 2013: Overview of the Cross-Language !ndian News Story Search (CL!NSS) Track Parth Gupta1 , Paul Clough2 , Paolo Rosso1 Mark Stevenson2 , and Rafael E. Banchs3 1 NLE Lab, Universitat Politû´cnica and abundant language resource. This edition of PAN@FIRE task, cross-language !ndia news story search (CL
Rosso, Paolo
Encoding transliteration variation through dimensionality reduction: FIRE Shared Task on
on Transliterated Search Parth Gupta1 , Paolo Rosso1 , and Rafael E. Banchs2 1 Natural Language Engineering Lab Department of Information Systems and Computation Universitat Polit`ecnica de Val`encia, Spain http://www.dsic.upv.es/grupos/nle are written in indigenous scripts for various rea- sons. In the light of this phenomenon, the search engines
: Profesores: Roger Corbacho (Coordinador de Arquitectura), Mariela Curiel (Coordinadora de IngenierûÙa de, Vicki Kaufman de Arquitectura, Rafael Sierra y Rubûˋn Marrero de IngenierûÙa Elûˋctrica, MarûÙa Quijada de dirigida a estudiantes de las carreras de IngenierûÙa, Arquitectura y Urbanismo. Este tipo de jornada se
to the firm's overall activity, because the greatest increase in productivity is achieved in this area; that construction companies can leverage the benefits in error reduction and logistics improvements that result PRODUCTIVITY Rafael Sacks1 and Ronen Barak2 ABSTRACT Parametric three-dimensional modelling of buildings
Cholesky-Conjugate Gradient Method for the Iterativeii) Incomplete Cho1esky-Conjugate Gradient method and iii)Kershaw, 1977). The conjugate-gradient method as originally
Dey, Abhijit
Subset Selection by Mallows' Cp: A Mixed Integer Programming ...
Department of Computer and Information Sciences,. Institute of Engineering, Tokyo University of Agriculture and Technology,. 2-24-16 Naka-cho, Koganei-shi,
E-Print Network 3.0 - anisotropic fast electron Sample Search...
Cho, **Gyoung-Bum Kim, **Dong... Anisotropic Conductive Film for high density Flip-Chip interconnection has met with growing interest over Source: Hwang, Sung Woo - School...
CHEMISTRY 3311, Fall 2003 Professor Walba
the wedges and dashes structure (1b) for the same compound. CHO CH2OH OHH HHO b) Indicate the configuration
Walba, David
Page 1 of 7 CHEMISTRY 3331, Spring 2005
- galactopyranose. Draw your structures carefully, and please leave out the H atoms. CHO OHH HHO HHO CH2OH OHH D
automata neural networks: Topics by E-print Network
and genetic programming. In this line of research, we have also Cho, Sung-Bae 115 Fuzzy neural network pattern recognition algorithm for classification of the events in...
Advanced Electrical Characterization of Semiconductor Nanowires
MOSFETs . . . . . . . . . . . . . . . Electrical Propertiesof surface states on electrical characteristics of inn andCho, and H. -Y. Cha, Electrical properties of ingan grown
Khanal, Devesh Raj
Chemical Hygiene Planh UNIVERSITY OF AlASKA
Chemical Hygiene Planh ôñ UNIVERSITY OF AlASKA ôñ ôñ FAIRBANKS INTRODUCTION.....................................................................................................3 C Chemical Hygiene Officer (CHO........................................................................................................ 8 F Reactive Chemicals
Hartman, Chris
Regulation of paraoxonase-1 and its role in the development of atherosclerosis
metabolism and biliary lipid secretion in rats fed fish oil.PON1 secretion from CHO cells requires apo A1 and lipid (8)
Gutierrez, Alejandra
E-Print Network 3.0 - altered expression pattern Sample Search...
and Medicine 51 A Scalable Hybrid Regular Expression Pattern Matcher James Moscola, Young H. Cho, John W. Lockwood Summary: A Scalable Hybrid Regular Expression Pattern Matcher...
Non-Petroleum-Based Fuel Effects on Advanced Combustion
Non Petroleum Based Fuel Effects on Advanced Combustion Project ID FT008 Investigators Jim Szybist, Bruce Bunting, Scott Sluder, Kukwon Cho, Robert Wagner, Dean Edwards, and...
ORIGINAL CONTRIBUTION Pharmacogenetic Study of Statin Therapy
ORIGINAL CONTRIBUTION Pharmacogenetic Study of Statin Therapy and Cholesterol Reduction Daniel I apolipoprotein E (APOE), apolipoprotein B (APOB), cho- lesteryl ester transfer protein (CETP), and the LDL
Posada, David
Quantification of black carbon in marine systems using the benzene polycarboxylic acid method: a mechanistic and yield study
GC/MS and NMR as 100% anthraquinone. Oxidation of anthracenehas been found to produce anthraquinone (Cho 1995).We hypothesize that the anthraquinone gener- ated was then
Ziolkowski, Lori A; Chamberlin, A.R.; Greaves, John; Druffel, Ellen R.M.
Fuel and Lubricant Effects
Fuel and Lubricant Effects Fuels Research, DOE agreements 13415, 13425 Bruce G. Bunting, Mike Bunce, Kukwon Cho, Jun Qu, Robert Crawford, Jim Szybist, Scott Sluder, John Storey,...
academic health sciences: Topics by E-print Network
is a vital force in the Las Vegas metropolitan area, educating desperately needed health care professionals and taking on some Cho, Hokwon 12 and Occupational Health...
academic health science: Topics by E-print Network
automatic document classification: Topics by E-print Network
Page Last Page Topic Index 1 Automatic construction of a concept hierarchy to assist Web document classification Woo Chul Cho Computer Technologies and Information Sciences...
CHO H H HO O O O R O O CO2H O O R O O CO2H O O O Me O CHO H HHO O O O O CO2H O O R R O O O CO2H H 6 [4
Trauner, Dirk
Template Synthesis of Hollow Sb Nanoparticles as a High-Performance Lithium Battery Anode Material
.; Beaudoin, B.; Naudin, E.; Morctette, M.; Tarascon, J. M. Solid State Ionics 2004, 166, 295. (6) Fernandez. Chem., Int. Ed. 2004, 43, 5987. (12) Kim, E.; Kim, M. G.; Kim, Y.; Cho, J. Electrochem. Solid-State. Soc. 2006, 153, A1633. (14) Kim, J.; Cho, J. Electrochem. Solid-State Lett. 2006, 9, A373. (15) Kim, E
Cho, Jaephil
Destruction mechanisms for formaldehyde in atmospheric temperature plasmas
,O) is a common pollutant of indoor air in residences and commercial buildings. The removal of CH,O from of a full accounting of the electron, ion, and neutral chemical kinetics in contaminated humid air. We find per million of CH,O in air/energy deposition). The elimination of the unwanted byproducts, CO and NO
Kushner, Mark
Lean-NOx Catalyst Development for Diesel Engine Applications
NO, C 3 H 6 , O 2 , H 2 O In 2 O 3 SiO 2 Alumina GCMS Acetaldehyde (CH 3 CHO) Acrolein (CH 2 CH-CHO) No N 2 produced In 2 O 3 SiO 2 Alumina GCMS Feed Gas NO, C 3 H 6...
This article was downloaded by: [LSE Library] On: 18 March 2013, At: 13:36
://www.tandfonline.com/loi/uasa20 Modeling and Forecasting Daily Electricity Load Curves: A Hybrid Approach Haeran Cho a , Yannig: Haeran Cho , Yannig Goude , Xavier Brossat & Qiwei Yao (2013): Modeling and Forecasting Daily Electricity, teaching, and private study purposes. Any substantial or systematic reproduction, redistribution, reselling
Fryzlewicz, Piotr
Fusion Engineering and Design 5152 (2000) 8591 Analysis of tritium kinetics of SIBELIUS beryllium
S. Cho a, *, M.A. Abdou b a Korea Basic Science Institute, 52 Yeoeun-dong, Yusung-ku, Taejeon, 305 ôˋ 2000 Elsevier Science B.V. All rights reserved. PII: S0920-3796(00)00378-1 #12;S. Cho, M.A. Abdou
Abdou, Mohamed
Analysis of C H...O hydrogen bonds
1 Analysis of C H...O hydrogen bonds in high resolution protein crystal structures from the PDB 1.4 Identification of C-H...O hydrogen bonds............................................. 1.4.1 The definition of a C-H...O hydrogen bond.................................... 1.4.2 Fixing the hydrogen and measuring the parameters
Contractive piecewise continuous maps modeling networks of inhibitory neurons.
ôÇistica Rafael Laguardia (IMERL), Fac. IngenierôÇia. Universidad de la RepôÇublica. Uruguay. Corresponding author. Address: Herrera y Reissig 565. C.P. 11300. Montevideo. Uruguay. Tel-fax: +598-2711-0621. E-mail: email@example.com Centro de MatemôÇatica. Fac. de Ciencias. Universidad de la RepôÇublica. Uruguay. ôÏDepartamento de Biomatem
Brain Research and DLM: An overview
Brain Research and DLM: An Overview Beverly J. Irby, Ed.D. Professor and Chair Sam Houston State University Rafael Lara-Alecio, Ph.D. Professor and Director Texas A&M University November 4, 2005 Basic Brain Information ? The brain research... us to ?see how mental functions map onto the brain structures? (Bruer, 1997, p. 4). Neuro- science and Education ? There are three well-established findings in developmental neurobiology: ? 1. Starting at infancy and continuing into later...
Irby, Beverly J.; Lara-Alecio, Rafael
MEXICO Gerardo SuzûÀn1, Alejandra de Villa-Meza2, Claudia MuûÝoz1, Rafael Avila-Flores2, Roxana Acosta3, Emmanuel Rivera4, Emilio Rendû°n1, and Gerardo Ceballos4 1) Facultad de Medicina Veterinaria, UNAM, Mexico, Mexico; 4) Instituto de EcologûÙa, UNAM, Mexico Methods Introduction Results Conclusions APV LBLC ôñFleas
Nacional Autû°noma de Mûˋxico, Universidad
The development of an effective portfolio assessment instrument
OF SCIENCE August 1993 Major Subject: Curriculum and Instruction THE DEVELOPMENT OF AN EFFECTIVE PORTFOLIO ASSESSMENT INSTRUMENT A Thesis by KAREN LEIGH ALDERETE Approved as to style and content by: Viola E. Florez ( Chair of Committee ) Rafael ra... (Schroeder and Hunsburger, 1989). A good writing curriculum for students at-risk should include several components. There must be an emphasis on meaningful conununication. Less emphasis should be placed on learning mechanics of the language (e. g...
Alderete, Karen Leigh
DLM Early Childhood Express: Assessment in Early Childhood
DLM Early Childhood Express Assessment in Early Childhood Dr. Rafael Lara-Alecio firstname.lastname@example.com Dr. Beverly J. Irby firstname.lastname@example.com What principles guide assessment for effectively improving student learning? ? Assessment is inherently... a process of professional judgment. ? Assessment is based on separate but related principles of measurement evidence and evaluation. ? Assessment decision-making is influenced by a series of tensions. ? Assessment influences student motivation...
Lara-Alecio, Rafael; Irby, Beverly J.
GRADO INGENIERA EN ORGANIZACIN INDUSTRIAL (MSTOLES) Curso 2014-15
(Aulario I- Aula 001) Hora Lunes Martes Miûˋrcoles Jueves Viernes 09:00 - 10:00 FIS * FIS * FIS * 10:00 - 11: InformûÀtica aplicada: Inmaculada Leyva FIS *: FûÙsica: Jesû¤s Miguel Seoane QUIM *: QuûÙmica: Rafael JuûÀrez- Aula 001) Hora Lunes Martes Miûˋrcoles Jueves Viernes 09:00 - 10:00 QUIM MAT II 10:00 - 11:00 MAT II FIS
Rey Juan Carlos, Universidad
Vicerrectorado de Profesorado, Titulaciones, Ordenacin Acadmica, Coordinacin y Campus.
Profesorado - Curso Acadûˋmico 2012-13 GRADO EN INGENIERIA AMBIENTAL % DoctoresCategorûÙa Nô¤ Profesores Nô¤ Larrosa, Juan No FISICA II FûÙsica FûÙsica Aplicada GarcûÙa Lû°pez, Alvaro No INTRODUCCION A LA INGENIERIA INGENIERIA AMBIENTAL Tecno. QuûÙmica y Ambiental IngenierûÙa QuûÙmica Van Grieken Salvador, Rafael Constantino
An Analysis of a Public School Prekindergarten Bilingual Montessori Program
Program Linda Rodriguez, Ed.D. Clinical Professor (Principal, Aldine Independent School District, Houston, TX) Beverly J. Irby, Ed.D. Professor and Chair Department of Educational Leadership and Counseling Genevieve Brown, Ed.D. Dean... College of Education and Applied Science Sam Houston State University Rafael Lara-Alecio, Ph.D. Associate Professor and Director, Bilingual Programs Martha Galloway, A.B.D. Clinical Professor Department of Educational Psychology Texas A...
Rodriguez, Linda; Irby, Beverly J.; Brown, Genevieve; Lara-Alecio, Rafael; Galloway, Martha
Evaluating a Master's Degree Program via Distance Education
Evaluating a Master?s Degree Program via Distance Education Dr. Rafael Lara-Alecio Janie Kemp Polly Trevi?o Fuhui Tong Raymond Castillo TTVN Conference Galveston, TX January 18, 2006 Texas A&M University Bilingual Education Program Dept.... of Educational Psychology College of Education and Human Development Texas A&M University Bilingual Education Programs ? Bilingual Certification Online Program ? PK-4 ? Texas Oral Proficiency Test (Spanish) included ? ESL Certification Intermediate...
Lara-Alecio, Rafael; Kemp, Janie; Treviþo, Polly; Tong, Fuhui; Castillo, Raymond
The Psychometric Properties of the Hispanic Bilingual Gifted Screening Instrument (HBGSI)
&M University in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Approved by: Co-Chairs of Committee, Rafael Lara-Alecio Sharolyn Pollard-Durodola Committee Members, Fuhui Tong Beverly J. Irby Richard Curry Head... of Department, Victor Willson December 2011 Major Subject: Educational Psychology iii ABSTRACT The Psychometric Properties of the Hispanic Bilingual Gifted Screening Instrument (HBGSI). (December 2011) Alma Linda Contreras-Vanegas, B.A.; M.Ed...
Contreras-Vanegas, Alma Linda
The Moon Glistens: A New Work for Band by Joni Greene: A Conductor's Analysis
in the various ensembles within the UT band program. During the spring semester of 2001, Greene met Rafael Hernandez, a masters candidate and a teaching assistant in the UT composition department. After submitting some short works for Hernandez review, she... soon began taking weekly composition lessons with him. This was Greenes first formal training in musical composition and lead to the completion of her first piece: Wave. After meeting with some success studying with Hernandez, Greene auditioned...
Simons, Chad P.
MAE TEACHING ASSISTANT / READER ASSIGNMENTS 1/7/13 12:12 COURSE INSTRUCTOR TA_name1 TA1 TA_name2 TA2 TA_name3 TA3 TA_name4 TA4 TA_name5 TA5 TAtotal
, Alex 1.00 Borrajo, Rafael 0.50 1.50 MAE110 McDonell McLarty, Dustin 0.50 0.50 MAE115 Brouwer Jarrahbashi, Dorrin 1.00 Fardadi, Mahshid 0.50 Taghavi, Shervin 0.50 2.00 MAE130A Papamoschou Hernandez, Franz.50 MAE130B LaRue Hernandez, Franz 1.00 Koster, Timothy 0.50 1.50 MAE146 Villac Nakhjiri, Navid 0.50 0
Mease, Kenneth D.
ApologÚa dramÃtica a JosÕ Gorostiza
el mundo del espectÃculo de JosÕ Gorostiza fue con el teatro de vertiente mexicanista, recientemente iniciado por el Teatro Regional Mexicano y el teatro SintÕtico, ambos fundados por Rafael M. Saavedra en 1921 y 1923, respectivamente. A partir de..., Ventana en la calle (1924), Manuel Horta ("Juana") y Fernando RamÚrez de Aguilar (La tona), por nombrar sµlo tres. En una entrevista de prensa, Quintanilla tratµ de definir el Teatro Mexicano del MurciÕlago y el origen de esta idea: Un dÚa en Nueva...
Schmidhuber, Guillermo
UnB/Universidade de Braslia Relatrio de Gesto
NTI Rafael Timû°teo de Sousa Jû¤nior Secretaria de Planejamento SPL Prof. Eduardo Tadeu Vieira Cûˋsar Brasil Centro deApoio ao Desenvolvimento Tecnolû°gico CDT Prof. Luiz Afonso Bermû¤dez Centro de Carlos Andreoli Centro de SeleûÏûÈo e de PromoûÏûÈo de Eventos CESPE Romilda GuimarûÈes Macarini Centro de
anodic materials: Topics by E-print Network
anode materia.l1-9 These materials have been showed large-14 the use of metal and carbon composites,15-20 and the introduction of nano- sized metals,21-25 have been Cho,...
advanced anodic materials: Topics by E-print Network
Micro-bioreactor design for Chinese hamster ovary cells
The research objective is to design a micro-bioreactor for the culture of Chinese Hamster Ovary (CHO) cells. There is an increasing demand for upstream development in high-throughput micro-bioreactors specifically for the ...
Goh, Shireen
Comment on {open_quote}{open_quote}Optimization of electrostatic deflectors{close_quote}{close_quote} [J. Vac. Sci. Technol. B {bold 13}, 142 (1995)
It is contended that contrarily to the claim of Szilagyi and Cho (Ref. 1), thecoma of deflection as well as field curvature can not be eliminated in the optimized electrostatic deflectors. (AIP)
Lencova, B. [Institute of Scientific Instruments, Academy of Sciences of the Czech Republic, Kralovopolska 147, 612 64 Brno (Czech Republic)] [Institute of Scientific Instruments, Academy of Sciences of the Czech Republic, Kralovopolska 147, 612 64 Brno (Czech Republic)
Compressibility of solar wind Bogdan A. Hnat
fluctuations[5] [1] V. Carbone et. al., PRL 75 (1995); [2] J. Cho and Lazarian, PRL 88 (2002) [3] D. Montgomery [6] A. Bershadskii and K. R. Sreenivasan, PRL 93 (2004) [7] J. V. Shebalin and D. Montgomery, JPP 39
Sengun, Mehmet Haluk
attenuates experimental autoimmune: Topics by E-print Network
More tests with water of different degrees of turbidity, and possibly wave filed at the water surface are in progress and wi... Simpson, A; Cho, H J; Liu, H 2014-01-01 8 Th1 Cells...
Detection of low concentration oxygen containing functional groups on activated carbon fiber surfaces through fluorescent labeling
Detection of low concentration oxygen containing functional groups on activated carbon fiber of surface functional groups (OH, COOH and CHO) on activated carbon fiber surfaces. The chromophores were rights reserved. Keywords: Carbon fibers; X-ray photoelectron spectroscopy; Infrared spectroscopy
Borguet, Eric
E-Print Network 3.0 - atmospheric pressure hf Sample Search Results
for: atmospheric pressure hf Page: << < 1 2 3 4 5 > >> 1 Atomic rearrangements in HfO2Si1-xGex interfaces Deok-Yong Cho and S.-J. Oha Summary: by PDA. PDA was per- formed...
anti-relaxation coating material: Topics by E-print Network
Cho,a, Materials Science Websites Summary: and deintercalation is re- ported, by thin-film encapsulation of the LiNiO2 particles by zirco- nium oxide (ZrO2). ZrHigh-Performance...
accident victims: Topics by E-print Network
Every year, traffic congestion and traffic accidents have been Cho, Sung-Bae 118 The Analysis of a Friendly Fire Accident using a Systems Model of Accidents* N.G. Leveson,...
accident victim conduite: Topics by E-print Network
Every year, traffic congestion and traffic accidents have been Cho, Sung-Bae 152 The Analysis of a Friendly Fire Accident using a Systems Model of Accidents* N.G. Leveson,...
accident victims bio-indicateurs: Topics by E-print Network
Every year, traffic congestion and traffic accidents have been Cho, Sung-Bae 119 The Analysis of a Friendly Fire Accident using a Systems Model of Accidents* N.G. Leveson,...
assisted high power: Topics by E-print Network
V. Braun , Jiung Cho, James H. Pikul, William P. King storage Secondary batteries High energy density High power density Lithium ion battery 3D battery electrodes a b s t r a c t...
The Effect of Culture Temperature on Recombinant IFN-? Production and Quality
The goal of this research project is to analyze the effect of culture temperature on the production and quality of IFN-? produced and secreted by suspension culture CHO cells.The effect of low temperature on IFN-? ...
Fox, Steven R.
Comparison of Inter Subject Variability and Reproducibility of Whole Brain Proton Spectroscopy
signal-intensity normalised metabolite concentrations of NAA, Cho and Cr. Healthy volunteers underwent imaging on two occasions using the same 3T Siemens Verio magnetic resonance scanner. At each session two identical Metabolic Imaging and Data...
Veenith, Tonny V.; Mada, Marius; Carter, Eleanor; Grossac, Julia; Newcombe, Virginia; Outtrim, Joanne; Lupson, Victoria; Nallapareddy, Sridhar; Williams, Guy B.; Sheriff, Sulaiman; Menon, David K.; Maudsley, Andrew A.; Coles, Jonathan P.
Active hyperspectral imaging using a quantum cascade laser (QCL) array and digital-pixel focal
, D. L. Sivco, and A. Y. Cho, "Quantum cascade lasers," Phys. Today 55(5), 34 (2002). 13. Daylight Solutions, Inc., www.daylightsolutions.com; Block Engineering LLC, www.blockeng.com. 14. B. G. Lee, M. A
Capasso, Federico
E-Print Network 3.0 - adhering escherichia coli Sample Search...
and biofilm formation of attaching and effacing Escherichia coli and identification of Fis... in Escherichia coli O157:H7 Jin-Hyung Lee Yong-Guy Kim Moo Hwan Cho Thomas...
A Study on Performance Degradation of PEMFC by Water Freezing...
Study on Performance Degradation of PEMFC by Water Freezing Workshop on Fuel Cell Operation at Sub-Freezing Temperatures Feb. 1-2, 2005 EunAe Cho Fuel Cell Research Center Korea...
Performance of Non-Gaussian Distribution Based Communication and Compressed Sensing Systems /
by relating it to a MISO MAC communi- cation problem. Weof the |T |-sender Gaussian MISO MAC Y T = b X X w (j?1)b+iprobability distribution P. The MISO codeword index cho- sen
Kwon, Hwan Joon
Instant Profiling: Instrumentation Sampling for Profiling Datacenter Applications
Instant Profiling: Instrumentation Sampling for Profiling Datacenter Applications Hyoun Kyu Cho Profile-guided optimization possesses huge potential to save costs for datacenters. Hardware performance programmers find code regions to optimize by monitoring datacenter applications continuously on live traffic
Tomkins, Andrew
E-Print Network 3.0 - assisted plasma arc Sample Search Results
Groupe d'Optique Atomique Collection: Physics 8 Gliding arc in tornado using a reverse vortex flow Chiranjeev S. Kalra, Young I. Cho,a Summary: . Instead the ignition was plasma...
E-Print Network 3.0 - arc discharge effects Sample Search Results
de mathmatiques Collection: Mathematics 5 Gliding arc in tornado using a reverse vortex flow Chiranjeev S. Kalra, Young I. Cho,a Summary: nonequilib- rium plasma is to use...
E-Print Network 3.0 - arc discharge ion Sample Search Results
of Texas at Austin Collection: Engineering 8 Gliding arc in tornado using a reverse vortex flow Chiranjeev S. Kalra, Young I. Cho,a Summary: nonequilib- rium plasma is to use...
Polymerization of Formaldehyde and Acetaldehyde on Ordered (WO3...
of their monomers and oligomers into the gas phase. The heats of H2CO and CH3CHO sublimation and polymerization determined based on our experiments are in good agreement...
1 Statement of the problem - Optimization Online
[3] H.J. Sussman and G. Tang, Shortest paths for the Reeds-Shepp car: a worked ... [10] G. Cho and J. Ryeu, An Efficient Method to Find a Shortest Path for a Car ...
The characterization, functional expression, and localization of the first arthropod myokinin receptor from the southern cattle tick, Boophilus microplus (Acari: ixodidae)
the southern cattle tick, Boophilus microplus. The deduced amino acid sequence was 40 % identical to the lymnokinin receptor. The receptor transcript is present in all tick life stages as determined by semiquantitative RT-PCR. When expressed in mammalian CHO...
Holmes, Steven P.
E-Print Network 3.0 - antagonist o-4-ethoxyl-butyl-berbamine...
Kim, Elliot Hawkes, Kyujin Cho, Matthew Jolda, Joe Foley and Robert Wood Summary: of micro-coil spring, we present a novel mesh-worm prototype that utilizes bio-inspired...
MATEMATICAS II MatemûÀtica Aplicada MatemûÀtica Aplicada GarcûÙa del Amo Jimûˋnez, Alejandro Josûˋ Si QUIMICA Tecno. QuûÙmica y Ambiental QuûÙmica OrgûÀnica Ramos Gallego, MarûÙa Mar Si QUIMICA Tecno. QuûÙmica y Ambiental QuûÙmica OrgûÀnica JuûÀrez MartûÙn, Rafael No QUIMICA QuûÙmica InorgûÀnica y AnalûÙtica QuûÙmica InorgûÀnica Pûˋrez
Aplicada Flores ûlvarez, Julio Si QUIMICA QuûÙmica InorgûÀnica y AnalûÙtica QuûÙmica InorgûÀnica SûÀnchez-Barba Merlo, Luis Fernando Si QUIMICA Tecno. QuûÙmica y Ambiental QuûÙmica OrgûÀnica JuûÀrez MartûÙn, Rafael ASIGNATURA DEPARTAMENTO AREA NOMBRE_COMPLETO DOCTOR QUIMICA QuûÙmica InorgûÀnica y AnalûÙtica QuûÙmica InorgûÀnica
Influence of kernel size on the presence of Aspergillus flavus, aflatoxin content and moisture content in Dominican Republic grown peanuts
, Aflatoxin Content and Moisture Content in Dominican Republic Grown Peanuts (Auqust, 1969) Teodoro Herrera-Perez, B. S. Ingeniero Agronomo, Escuela Superior de Agricultura "Antonio Narro". Directed by: Dr. David W. Rosberg. Incidence oi As..., Dominican Republic for provid- ing the friendly environment which made this work and my stay in this c ountry !!rore enjoyable. I a!r d e;:!Iy ir d; bt-. d Lo Dr. Rafael Nirabal Roclriguc z and Nr. Tais Crouch for their friendsnip and help which fa- ci1...
Herrera-Perez, Teodoro
Chemical composition of esophageal-fistula forage samples as influenced by drying method, salivary leaching and sample preparation
in partial fulfillment of the requirement for the degree of YASTER OF' SCI"'NCE, De"ember 1g76 CHEJJICAL COY!POSITION OF ESOPHAGEAL-FISTULA FORAGF SA(vPLES AS INFLUENCED BY DRYING I'METHOD, SALIVARY LEACHING AND SAMPLE PREPARATION A Thesis RAFAEL... ARISTIDES ACOS A-GONZALEZ Approved as to style and content by! (Cha rman o Committee) ((iced of Department) ( I'~iamb r ) Yemb r ) Dcc: mb~+~g~n'jrr ABSTRACT Chemical Composition of Esophageal-Fistula Forage Samples as Influenced by Drying Nethod...
Acosta-Gonzalez, Rafael Aristides
Latin American Theatre Review, Volume 11, Number 1: Book Reviews
"Conclusiones," diciendo que "aun el techo" se utilizaba como entrada para las mujeres del pueblo (p. 249). Tan peregrina afirmaciµn se basa en "un documento de 1678 [que] habla de la reparaciµn del 'tejado donde cobran a las mujeres' (Doc. 15 de 1678)," y en... amanecer (1955) by AgustÚn Cuzzani (Argentina); El robo del cochino (1961) by Abelardo Estorino (Cuba); La muerte no entrarà en palacio (1957) by Rene MarquÕs (Puerto Rico); La pasiµn segºn AntÚgona PÕrez (1970) by Luis Rafael SÃnchez (Puerto Rico...
Scion dominance and related factors influencing compatability in citrus graft unions
SCION DOMINANCE AND RELATED FACTORS INFLUENCING COMPATIBILITY IN CITRUS GRAFT UNIOHS A The?ia SC H? Clntr&i August 194C Approval as to atyl* and content recommended* m t m m m m m m belated factors nfHOTQiua compatibilitt in cithus m m r... Major Subjectt Horticulture By Rafael H* Clntr&n August 1946 SCI01T DOHIH/ffiCB AND RELATED FACTORS INFLUENCING COMPATIBILITY ITT CITRUS GR APT UNIONS 14-f 706 'The writer1 wishes to express M s sincere approeiation to Dr* Guy W? Adrianee# Head...
Cintron, Rafael H.
Rajesh Dham | Department of Energy
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of Energy Power.pdf11-161-LNG |September 15,2015 | DepartmentLoansDepartment of EnergyEvent |Rafael
Ram Shenoy | Department of Energy
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) "of Energy Power.pdf11-161-LNG |September 15,2015 | DepartmentLoansDepartment of EnergyEvent |RafaelRam
The Impact of Science Notebook Writing on ELL and Low-SES Students' Science Language Development and Conceptual Understanding
in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Approved by: Chair of Committee, Rafael Lara-Alecio Co-Chair of Committee, Fuhui Tong Committee Members, Sharolyn Pollard-Durodola Yeping Li Beverly Irby Head... professors at Texas A&M: Dr. Lara, my chair, for the opportunity and generous support; Dr. Tong, my co-chair, for insight into the analysis and results; Dr. Irby for aiding in the conceptualization of the project; Dr. Durodola, for feedback on my writing...
Huerta, Margarita
Sand Bluff Wind Farm | Open Energy Information
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 No revisionEnvReviewNonInvasiveExplorationUT-g Grant ofRichardton Abbey WindSamsungFarms SectorMateo,Rafael,Bluff
Rancher Brings Wind Power to Arizona | Department of Energy
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Year in3.pdfEnergyDepartmentEnergy Data Reporting Guide RadiationRafael L. BrasRancher
Rapid Freeform Sheet Metal Forming
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Year in3.pdfEnergyDepartmentEnergy Data Reporting Guide RadiationRafael L.Freeform Sheet
Angular dependence of metamagnetic transitions in HoNi2B2C
of moments along the @110# axes. Angular dependence of metamagneti P. C. Canfield, S. L. Bud?ko Ames Laboratory and Department of Physics and Astronomy A. Lacerd National High Magnetic Field Laboratory?Pulse Facility, Los D. Farrell and E. Department.... P. Beyermann, P. C. Canfield, and S. L. Bud?ko, Phys. Rev. B 54, R3772 ~1996!. 11B. K. Cho, P. C. Canfield, and D. C. Johnston, Phys. Rev. B 53, 8499 ~1996!. 12P. C. Canfield, B. K. Cho, and K. W. Dennis, Physica B 215, 337 ~1995!. 13 J...
Canfield, PC; Budko, SL; Cho, BK; Lacerda, A.; Farrell, D.; JohnstonHalperin, E.; Kalatsky, VA; Pokrovsky, Valery L.
Polymerization of acetaldehyde using tetraiso-Propyl titanate as a catalyst
with palladous chloride as a catalyst forms vinylacetate and water. ~ CH =CHO CDCH i (CH -CHQ CDCH l 2 3 n Vinylacetate monomers are polymerized by radical initiation to form polyvinyl acetate. (CH2-CHO ~ COCH3) n H or OH (CH -CH)n n OH polyvinyl... of tetravinyl titanate by procedure (B) (21) Hydrolysis reaction of vinyl titanate RESULTS AND DISCUSSION The materials obtained from the polymerization reaction at high temperature The materials obtained from the polymerization of acetaldehyde at 200'C...
Makita, Muneharu
Catalytic reforming methods
DOE Patents [OSTI]
A catalytic reforming method is disclosed herein. The method includes sequentially supplying a plurality of feedstocks of variable compositions to a reformer. The method further includes adding a respective predetermined co-reactant to each of the plurality of feedstocks to obtain a substantially constant output from the reformer for the plurality of feedstocks. The respective predetermined co-reactant is based on a C/H/O atomic composition for a respective one of the plurality of feedstocks and a predetermined C/H/O atomic composition for the substantially constant output.
Tadd, Andrew R; Schwank, Johannes
Spectroscopic and theoretical investigation of selected cyclic and bicyclic molecules in their ground and excited electronic states
.................................................................. 81 12 CRD transition frequencies (in cm-1) and assignments for 2CHO............. 87 13 CRD transition frequencies (in cm-1) and assignments for 2-CHO-d3....... 89 14 Calculated relative out-of-plane displacements (é) of C1, C4, and C6... is planar in both the ground and S1(?,?*) states. A complete vibrational assignment was carried out for 14DHN using the infrared and Raman data and aided by DFT calculations. The ab intio calculations carried out on 2-methyl-2-cyclopenten-1-one (2MCP...
Rishard, Mohamed Zuhair Mohamed
Rephasing: A Transformation Technique for the Manipulation of Timing Constraints
is that phases can be cho- sen to optimize the algorithm for metrics such as area and power. Moreover, rephasing Algorithm transformations have emerged as impor- tant optimization tools in the process of high-level synthe. The advantage of rephasing is that phase values can be chosen to transform and optimize the algo- rithm
Potkonjak, Miodrag
{yjoh, jmcho, jbyoo, firstname.lastname@example.com A Technique to Specify and Analyze Reactive and Real-Time Software
and Analyze Reactive and Real-Time Software Younju Oh, Jaemyoung Cho, Junbeom Yoo, Sungdeok Cha Div. of CS, Dept. of Electrical Engineering and Computer Science Korea Advanced Institute of Science and Technology requirements specification (SRS). Many specification languages are suggested to specify reactive and real
Microscopic model for the magnetic subsystem in HoNi2B2C
~1996!. 2 P. C. Canfield, S. L. Bud?ko, B. K. Cho, A. Lacerda, D. Farrell, E. Johnston-Halperin, V. A. Kalatsky, and V. L. Pokrovsky, Phys. Rev. B 55, 970 ~1997!. 3 A. I. Goldman, C. Stassis, P. C. Canfield, J. Zarestky, P. Derve- parameters. From a...
Kalatsky, VA; Pokrovsky, Valery L.
Corresponding author: TaeWon Seo E-mail: email@example.com
Corresponding author: TaeWon Seo E-mail: firstname.lastname@example.com Journal of Bionic Engineering 6 , TaeWon Seo2 , Byungwook Kim1 , Dongsu Jeon1 , Kyu-Jin Cho1 , Jongwon Kim1 1. School of Mechanical
Kim, Jongwon
The design, synthesis and evaluation of tetra-substituted pyr-idines as potent 5-HT2C receptor agonists
and phentermine/topiramate. Ann. Pharmacother. 2013, 47, 1007-1016. (6) Monck, N. J. T.; Kennett, G. A. 5-HT2C ligands: recent progress. Prog. Med. Chem. 2008, 46, 281-390. (7) Yang, H. Y.; Tae, J.; Seo, Y. W.; Kim, Y. J.; Im, H. Y.; Choi, G. D.; Cho, H...
Rouquet, Guy; Moore, Dianna E.; Spain, Malcolm; Allwood, Daniel M.; Battilocchio, Claudio; Blakemore, David C.; Fish, Paul V.; Jenkinson, Stephen; Jessiman, Alan S.; Ley, Steven V.; McMurray, Gordon; Storer, R. Ian
through the digestive tract of patients with a malabsorption syndrome. In addition, our
digestibility car- bon from dietary CHO. Effect of algal fibre supplementation (Eucheuma cottonii) on intestinal of their nutritional properties, this work inves- tigated the possible effects of algal polysac- charides sequence of test meals (800 g of maize starch + casein) sup- plemented either with 40 g of algal fibres
1104 OPTICS LETTERS / Vol. 25, No. 15 / August 1, 2000 Selective delivery of laser energy to biological tissue
1104 OPTICS LETTERS / Vol. 25, No. 15 / August 1, 2000 Selective delivery of laser energy and were cho- sen as an example.4,5 Optical energy is delivered into tissue through a contacting optical but below the critical angle for high-index tissues, thus allowing optical energy to be coupled efficiently
Massachusetts at Lowell, University of
Chapter 8 -Carbohydrates Hydrates of Carbon: Cm(H2O)n
-glyceraldehyde are reference molecules for assignment of stereochemistry (absolute configuration). CH2OH C OHH CHO CH2OH C HHO the same configuration as D-glyceraldehyde. ! = CH2OH OH OH HO O CH2OH D-Fructose CH2OH C O C HHO C C CH2OH
O'Neil, Joe
Probing the role of chloride in Photosystem II from Thermosynechococcus elongatus by exchanging chloride for iodide
Center, Ehime University, Bunkyo-cho, Matsuyama Ehime, 790ôÙ8577, Japan, and PRESTO, Japan Science 2012 Keywords: Photosystem II Chloride Oxygen evolution The active site for water oxidation in Photosystem II (PSII) goes through five sequential oxidation states (S0 to S4) before O2 is evolved
Integrated Computer-Aided Engineering 9 (2002) 363372 363 Fusion of neural networks with fuzzy logic
in statis- tics, management sciences, and pattern recognition [1, 33]. A general result from the previous with fuzzy logic and genetic algorithm Sung-Bae Cho Department of Computer Science, Yonsei University, 134 softcomputing techniques. The first method based on fuzzy logic nonlinearly combines objective evidences
Density functional studies of the electronic structure and adsorption at molybdenum oxide surfaces
of these processes depend on the speciôÛc surface orientation. As an example we mention the allyl to acrolein conversion in a surface reaction propeneCH3û?CHCH2 A allylCH2û?CHû?CH2 A acroleinCH2CHû?CHO Catalysis Today 50
This paper has been downloaded from the Building and Environmental Thermal Systems Research Group at Oklahoma State University
tower loops. Circulating cooling tower water typi- cally contains an excess amount of mineral ions, such as calcium and magnesium, due to evaporation of water, thus making the water hard (Cho, et al. 2003). When hard water is heated inside compact BPHEs, the calcium and bicarbonate ions precipitate because a drop
Study on plasma assisted metal-organic chemical vapor deposition of Zr,,C,N... and Ti,,C,N... thin films and in situ plasma diagnostics with optical
films and in situ plasma diagnostics with optical emission spectroscopy S. J. Cho, S.-H. Nam, C.-K. JungStudy on plasma assisted metal-organic chemical vapor deposition of Zr,,C,N... and Ti,,C,N... thin C,N films were synthesized by pulsed dc plasma assisted metal-organic chemical vapor deposition
1 LOCAL LINEAR PID CONTROLLERS FOR NONLINEAR CONTROL Jing Lan1, Jeongho Cho1, Deniz Erdogmus2, email@example.com, email@example.com, firstname.lastname@example.com Abstract Nonlinear PID design is difficult if one approaches modeling approach with traditional linear PID controller design techniques to arrive at a principled
Slatton, Clint
On the Interplay of Parallelization, Program Performance, and Energy Consumption
to either minimize the total energy consumption or minimize the energy-delay product. The impact of staticOn the Interplay of Parallelization, Program Performance, and Energy Consumption Sangyeun Cho through parallel execution of applications, suppressing the power and energy consumption remains an even
Marchal, Loris
Journal of the Korean Physical Society, Vol. 44, No. 1, January 2004, pp. 153156 Effects of Phosphorus Implantation and Subsequent Growth on
electron affinity (NEA) and chemical inertness [1Ù3]. Es- pecially, polycrystalline diamond films grown: +82-2-880-7282; Fax: +82-2-882-4658 tents [4]. Polycrystalline diamond films have rough surfaces of Diamond Euo Sik Cho, Byung-Gook Park and Jong Duk Lee Inter-University Semiconductor Research Center
Lee, Jong Duk
PUBLISHED ONLINE: 15 NOVEMBER 2009 | DOI: 10.1038/NPHYS1455 Experimental probing of the interplay between
Technology, Japan Science and Technology Agency, Sanban-cho 5, Chiyoda-ku, Tokyo 102-0075, Japan, 4Institute arrangement. This implies that carrier localization leads to a phase separation into ferromagnetic and non-1-1, Aoba-ku, Sendai 980-8577, Japan, 2Institute of Physics, Polish Academy of Sciences, al. Lotnikû°w 32
Loss, Daniel
IOP PUBLISHING PHYSIOLOGICAL MEASUREMENT Physiol. Meas. 28 (2007) 335347 doi:10.1088/0967-3334/28/4/001
-1, Hirosawa, Wako Saitama 351-0198, Japan 2 Malaysia University of Science and Technology, Unit GL33, Block C 8th Floor, Minami-Watarida-cho, Kawasaki-ku, Kawasaki 210-0855, Japan E-mail: wlwoon that the biological changes leading to AD begin long before the appearance of clinical symptoms, by which time
Cichocki, Andrzej
Organic solar cells using few-walled carbon nanotubes electrode controlled by the balance between sheet resistance and the transparency
Technology, Hokuryo-cho, Matsue, Shimane 690-0816, Japan Received 6 January 2009; accepted 24 February 2009 of Engineering, Osaka University, 2-1 Yamada-oka, Suita, Osaka 565-0871, Japan 4 Shimane Institute for IndustrialV is sufficiently high to ensure the hole collection leading to better photovoltaic response.4 However the best
Liu, Jie
http://w3.pppl.gov/~ Calibrating
web page: http://w3.pppl.gov/~ zakharov Calibrating JET for equilibrium reconstruction 1 (iron core by US DoE contract No. DE--AC020--76--CHO--3073. PRINCETON PLASMA PHYSICS LABORATORY PPPL 1 #12 in magnetic signals due to the presence of the iron core and due to eddy currents in passive conductors
Zakharov, Leonid E.
I Am Crrarn Soc, 1 5 [2] 316-2r (1992) Distribution of Matrix Cracks in a Uniaxial Ceramic Composite
Composite Chongdu Cho,*John W. Holmes," and James R. Barber Department of Mechanical Engineering and Applied cracking and debonding in uniaxial composites loaded in tension predict that the matrix stress varies only model of a composite and by direct experimental measurements of crack spacing. In the limit
Barber, James R.
Optimal strategies for the surveillance and control of forest pathogens: A case study with oak wilt
University, Graduate School of Global Environmental Studies, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan of infected trees, rates of infection growth, and costs of surveillance and control. In our application to oak (Castanea dentata), and now the Dutch elm disease fungus (Ophiostoma novo-ulmi) and the oak wilt fungus
Fried, Jeremy S.
Ultrasonic backscatter coefficient quantitative estimates from Chinese hamster ovary cell pellet biophantoms
Ultrasonic backscatter coefficient quantitative estimates from Chinese hamster ovary cell pellet August 2010; accepted 6 August 2010 A cell pellet biophantom technique is introduced, and applied verification purposes. BSC estimates from CHO cell pellet biophantoms of known number density were performed
Illinois at Urbana-Champaign, University of
Supporting Information Efficient and Sequence-Specific DNA-Templated Polymerization of PNA Aldehydes
Synthesis of Boc-t-CHO PNA monomer aldehyde (S3) The basic protocol for formation of the allyl-substituted secondary amine (S1) and its coupling to thymine-1-acetic acid was adapted from Puschl, A.; Sforza, S.; Haaima, G.; Dahl, O.; Nielsen, P.E. Tetrahedron Letters 1998, 39, 4707. Preparation of allyl
Liu, David R.
Subcellular In Vivo 1 H MR Spectroscopy of Xenopus laevis Oocytes
Subcellular In Vivo 1 H MR Spectroscopy of Xenopus laevis Oocytes Seung-Cheol Lee,* Jee-Hyun Cho and Technology, Yusung-gu, Daejeon 305-701, Korea ABSTRACT In vivo magnetic resonance (MR) spectra are typically was designed to evaluate the potential of localized MR spectroscopy to investigate subcellular phenomena. Using
Hammerton, James
Evaluation of Network Trust Using Provenance Based on Distributed Local Intelligence
@illinois.edu, email@example.com, firstname.lastname@example.com City University of New York University of Illinois at Urbana Champaign University of California, Davis ôÏU.S. Army Research Laboratory Abstract--Provenance can such as energy loss, en- vironmental conditions or exhausting sources. We introduce a node-level trust
California at Davis, University of
-cho, Mizusawa City, Iwate 023-0861, Japan. Introduction: Visible multiband spectroscopy us- ing ground laser at 5 and 15 mJ in energy as a space-weathering simulation [1] at Mizusawa Astrogeodynamics]. Spectral transmittance data of Hayabusa/AMICA filters were taken from [3]. Space-Weathering Indices: It has
Hiroi, Takahiro
University , Engineering
, Princeton Plasma Physics Laboratory Presented at Seminar of Department of Nuclear Engineering Massachusetts{AC020{76{CHO{3073. Leonid E. Zakharov, Department of Nuclear Engineering, MIT , Feb.26, 2001, Cambridge acting on the guide wall. This design concept opens opportunities for nuclear engineers and technologists
The Call of the Crowd: Event Participation in Location-based Social Services
. Calabrese, F.; Pereira, F. C.; Di Lorenzo, G.; Liu, L.; and Ratti, C. 2010. The geography of taste: Analyzing cell-phone mobility and social events. In Pervasive10. Cho, E.; Myers, S. A.; and Leskovec, J. 2011. Friendship and mo- bility: user movement...
Georgiev, Petko; Noulas, Anastasios; Mascolo, Cecilia
Active Optics Performance Study of the Primary Mirror of the Gemini Telescopes Project
Active Optics Performance Study of the Primary Mirror of the Gemini Telescopes Project Myung K. Cho Optical Sciences Center in the University of Arizona Tucson, AZ 85721 and Gemini Telescopes Project P. O. Box 26732 Tucson, AZ 85726ôÙ6732 Gemini Preprint #9 #12; Active optics performance study of the primary
This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research
-cho Hakodate, Hokkaido 041-8611 Japan b Department of Physical & Environmental Sciences, University of Toronto, Toronto, Ontario, Canada M1C 1A4 a r t i c l e i n f o Article history: Received 16 December 2009 Received, there is considerable uncertainty with regards to the impact on the broader system dynamics. In this study, our
Arhonditsis, George B.
The Focusing Optics x-ray Solar Imager: FOXSI Sam Kruckera,b, Steven Christec, Lindsay Glesenera,d, Shin-nosuke Ishikawaa, Stephen
University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan ABSTRACT The Focusing Optics x-ray Solar Imager. Today's leading solar HXR instrument, the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI, solar physics, solar flares, silicon strip detectors, grazing-incidence optics, high-energy x-ray optics
California at Berkeley, University of
NSF/SRC Engineering Research Center for Environmentally Benign Semiconductor Manufacturing Integrated ESH Assessment
Integrated ESH Assessment: Cu CVD and ALD Unit Process Optimization (Thrust C, Task C-5) Wei Lei, Soon Cho 28 37Integrated ESH Assessment Major Deliverable Deliverable Thrust BThrust A Thrust C Thrust D Perspective ôñ Project Objectives ôÙ Exploit physics-based dynamic simulation to extract ESH metrics as function
Utility Accrual Real-Time Scheduling for Multiprocessor Embedded Systems
Utility Accrual Real-Time Scheduling for Multiprocessor Embedded Systems Hyeonjoong Cho a Binoy We present the first Utility Accrual (or UA) real-time scheduling algorithm for mul- tiprocessors, called global Multiprocessor Utility Accrual scheduling algorithm (or gMUA). The algorithm considers
Ravindran, Binoy
30TH INTERNATIONAL COSMIC RAY CONFERENCE Status and Prospect of Telescope Array (TA) Experiment
. KASAHARA1 , H. KAWAI2 , S. YOSHIDA2 , H. YOSHII3 , T. CHUNG4 , S.W. NAM4 , S. OH4 , I.H. PARK4 , J.H. PARK4-5-1 Akebono-cho, Kochi, 780-8520 Japan. 12 Los Alamos National Laboratory, Los Alamos, NM 87545, USA 13 Max
Photon echoes and related four-wave-mixing spectroscopies using phase-locked pulses
. Combining two phase-locked pulse excitation with time-resolved detection of the spontaneous light emissionPhoton echoes and related four-wave-mixing spectroscopies using phase-locked pulses Minhaeng ChoRochester, Rochester, New York 14627 (Received 3 December 1991; accepted 6 January 1992) The use of phase-locked pulses
Scherer, Norbert F.
Advanced Time-Frequency Mutual Information Measures for Condition Based Maintenance of Helicopter Drive Trains
Drive Trains GRA: David Coats, Principal Investigators: Dr. Yong-June Shin, Abdel Bayoumi Motivation-1409. ôñ Kwangik Cho, David Coats, John Abrams, Nicholas Goodman, Yong-June Shin, and Abdel E. Bayoumi point for examining eccentricities in gear- boxes, drive components, and motor vibration signatures
Almor, Amit
Energy Sciences Institute Talks at West Campus
such as pumped hydroelectric storage, compressed air energy storage (CAES), flywheels, and electrochemical electric storage devices, but viable battery technology able to store large amounts of electric energyEnergy Sciences Institute Talks at West Campus Jaephil Cho Professor at SAMSUNG SDI-UNIST Future
Agents on the Web The Sentient Web
Agents on the Web The Sentient Web "I n a startling revelation, a team of uni- versity scientists. In spite of the ominous tone typically cho- sen for dramatic effect, a sentient Web would be more helpful and much easier for people to use. When people find the Web frustrating, it is usual- ly not because
Huhns, Michael N.
Invited review article Advances in Fourier transform infrared spectroscopy of natural glasses
, Christchurch 8140, New Zealand b School of Environmental Sciences, University of Liverpool, Liverpool, UK c Research and Development Center for Ocean Drilling Science, Japan Agency for Marine Earth Science and Technology (JAMSTEC), 2-15 Natsushima-cho, Yokosuka, Kanagawa 237-0061, Japan d Department of Geological
Watkins, Jim
Earth and Planetary Science Letters, 83 (1987) 313-328 313 Elsevier Science Publishers B.V., Amsterdam -Printed in The Netherlands
, (France) 7Japan Marine Science and Technology Center, 2-15 Natsushima Cho, Yokosuka 237 (Japan) 8 of the dives provide new constraints on the geodynamics of these subduction zones. In the Japan and Kuril on the northern Japan Trench margin deduced from the seismic profiles and DSDP drilling was confirmed. Several
Demouchy, Sylvie
JOM, 2010, 62(3): p. 25-26. Symposium Preview: High Strain Rate Behaviors of Composites and Heterogeneous
25 JOM, 2010, 62(3): p. 25-26. Symposium Preview: High Strain Rate Behaviors of Composites and Heterogeneous Materials Nikhil Gupta and Kyu Cho The use of composite materials has been rapidly increasing and the usage is now over 8 million tons/year. In a significant advancement, composite materials comprise over
Gupta, Nikhil
Proceedings of IMECE 2006 2006 ASME International Mechanical Engineering Congress and Expo
of 2.5 at a volume fraction of 1%). Pak and Cho [10] studied the convective heat transfer coefficient in the experimental data published in the open literature. Given the inconsistency in the data, it is impos- sible/mK Q = heat flow rate, W rp = particle radius, m SSM = steady-state method T = temperature, K THW
Bahrami, Majid
Assessment of Relevant Physical Phenomena Controlling Thermal Performance of Nanofluids
of heat transfer fluids has shown several attractive characteristics including the possibility%). Pak and Cho [10] studied the convective heat transfer coefficient of nanofluids in cylindrical tubes been observed in the experimental data published in the open literature. Given the inconsistency
Simulation Vector Generation from HDL Descriptions for ObservabilityEnhanced Statement Coverage
generated. For vector generation, we proposea novel technique to set up constraints basedon the choôÙ sen generation, and the size of the generated vecôÙ tor set. However, the most important step here is to helpSimulation Vector Generation from HDL Descriptions for ObservabilityôÙEnhanced Statement Coverage
Devadas, Srinivas
JOURNAL DE PHYSIQUEIV Colloque C7, suppltment au Journal de Physique III, Volume 4,juillet 1994
Percutaneous absorptiometry by UV laser photoacoustic method using a novel open-ended cell combined with lightResearch Center,Shiseido Company Ltd., 1050Nippa-cho, Kohoku-ku, Yokohama223,Japan *Dwartment ofIndustrial was developed. This PA cell was constructed by processing the end of a light guide as the sample chamber
High power rechargeable batteries Paul V. Braun
High power rechargeable batteries Paul V. Braun , Jiung Cho, James H. Pikul, William P. King storage Secondary batteries High energy density High power density Lithium ion battery 3D battery electrodes a b s t r a c t Energy and power density are the key figures of merit for most electrochemical
Braun, Paul
Sparse PCA: Concepts, Theory, and Algorithms Jing Lei, Department of Statistics, CMU
. Biostat Department Seminar, Nov 7, 2013 #12;Collaborators Vince Q. Vu, Stat. Dept. OSU Karl Rohe, Stat. Dept. U.W. Madison Juhee Cho, Stat. Dept. U.W. Madison #12 = arg max UT U=Id, U 2,0R0 Trace(UT ^U). #12;About This Result ôñ Good news ôñ Exact minimax error rate
Lei, Jing
Absorption cross-section 139 Accumulation mode, of aerosol 146
133, 151 residence times 153 size distributions 144 Air composition 2 molecular weight 4, 6 Albedo 122 dioxide Coagulation (aerosol) 146 Column model 32 Conditional unstability 56 Continuity equation 75261 INDEX A Absorption cross-section 139 Accumulation mode, of aerosol 146 Acetaldehyde (CH3CHO
Jacob, Daniel J.
ImageCat, Inc. Remote Sensing for PostRemote Sensing for Post--disasterdisaster
to Salt Lake City SAR simulation The way forward #12;ImageCat, Inc. The IdeaThe Idea Remote sensing and non-damaged structures #12;ImageCat, Inc. Application to Salt Lake CityApplication to Salt Lake City 0 AssessmentBridge Damage Assessment Beverley J. Adams Ph.D. Charles K. Huyck Sungbin Cho Ronald T. Eguchi
Shinozuka, Masanobu
Dynamics of Tilt-based Browsing on Mobile Devices
Cho,S.J. Murray-Smith,R. Choi,C. Sung,Y. Lee,K. Kim,Y.B. CHI '07 extended abstracts on Human factors in computing systems, http://doi.acm.org/10.1145/1240866.1240930 pp 1947 - 1952 ACM Press
Cho, S.J.; Murray-Smith, R.
VALIDATION OF THE eCALC COMMERCIAL CODE-COMPLIANT SIMULATION VERSUS MEASURED DATA FROM AN OFFICE BUILDING IN A HOT AND HUMID CLIMATE
for the case-study building were performed and reported in Cho and Haberl (2008). In this paper an extension of the previous work is presented using the eCALC commercial simulation model, which uses simplified geometry and ASHRAE Standard 90.1-compliant...
Cho, S.; Haberl, J.
TransNIEMO: ECONOMIC IMPACT ANALYSIS USING A MODEL
TransNIEMO: ECONOMIC IMPACT ANALYSIS USING A MODEL OF CONSISTENT INTERREGIONAL ECONOMIC AND HIGHWAY of Industrial and Systems Engineering; and the School of Policy Planning and Development Qisheng Pan, Associate of Industrial and Systems Engineering JoongKoo Cho Epstein Department of Industrial and Systems Engineering
Wang, Hai
E-Print Network 3.0 - arteriovenous malformations involving Sample...
Ecology 32 Practical approaches to incidental findings in brain imaging J. Illes, PhD, M.P. Kirschen, PhD, E. Edwards, PhD, P. Bandettini, PhD*, M.K. Cho, PhD*, P.J. Summary: for...
E-Print Network 3.0 - arteriovenous malformation involving Sample...
Adaptive Behavior of Fuzzy System Optimized by Genetic Algorithm
wheels and two small Teflon balls placed under its platform. The wheels are controlled by two DC motorsAdaptive Behavior of Fuzzy System Optimized by Genetic Algorithm Sung-Bae Cho and Seung-Ik Lee Dept the control system of simulated robots [l],[3], [9], [13]. The rich variety of structures that have appeared
12009Federal Register / Vol. 77, No. 39 / Tuesday, February 28, 2012 / Notices attending the meeting. To accommodate
Committee, Office of Energy & Environmental Industries, Room 4053, 1401 Constitution Ave. NW., Washington. The Assistant Secretary for Administration, with the concurrence of the delegate of the General Counsel within 90 days of the meeting. Man K. Cho, Team Leader for Energy, Office of Energy and Environmental
Vol. #12, No. #1 January 2008 University of Connecticut
Grant 8 UConn Demonstrates Biodiesel Production 9 Associates Program Staff Member Presentations 10 of equipment funding in the recent Provost's Research Equipment Competition. The six, cho- sen from 31 proposals submitted, include a total of 62 researchers who are on the teams that will use the equipment
Alpay, S. Pamir
Worms need microbes too: microbiota, health and aging in Caenorhabditis elegans
*, David Gems Keywords: aging; C. elegans; metformin; microbiota; type-2 diabetes DOI 10.1002/emmm, diabetes, metabolic syndrome, autoimmune disorders, inflam- matory bowel disease, cancer and aging (Cho and type-2 diabetes, and perhaps aging. These morbidities have a profound impact in terms of individual
Gems, David
Investigation of Quaternary eustatic shorelines in the Galveston Bay Region, Texas
) SOUTH FRAVCE (D pcreU MOROC. CO (Cho hen Ruhlatan C gout, Ze ocr) IBrc I, ZI I I) (htour Zc n ) ORTU- (FRSEY CAL VURTH I'RANCE )Dc L . no)he, Z unrr SOUTH DOWNS (Sp 1. Zr'r ) HAMP. 9'HHIE H urn ) DEVON (Cree ) LO AND I. or...
Henry, Vernon James
Electrochemical treatment of human waste coupled with molecular hydrogen production
in a hydrogen fuel cell. Herein, we report on the efficacy of a laboratory-scale wastewater electrolysis cell an electrolysis cell for on-site wastewater treatment coupled with molecular hydrogen production for useElectrochemical treatment of human waste coupled with molecular hydrogen production Kangwoo Cho
Heaton, Thomas H.
Steam-Powered Sensing Chengjie Zhang
Steam-Powered Sensing Chengjie Zhang 1 Affan Syed 1,2 Young Cho 1 John Heidemann 1 chengjie blockages in steam pipelines of a production oilfield. First, we eliminate the high cost of bringing power in steam pipelines and full blockages in hot water pipelines. Finally, we evaluate our "steam
The insecticide 1,1,1-trichloro-2,2-bis(p-chlorophenyl) ethane (DDT) alters the membrane raft location of the TSH receptor stably expressed in Chinese hamster ovary cells
DDT is a highly lipophilic molecule known to deplete membrane rafts of their phosphoglycolipid and cholesterol contents. However, we have recently shown that DDT can also alter the thyroid homeostasis by inhibiting TSH receptor (TSHr) internalization. The present study was undertaken to verify whether DDT goitrogenic effects are due to the insecticide acting directly on TSHr or via alteration of the membrane rafts hosting the receptor itself. Our results demonstrate that, in CHO-TSHr transfected cells, TSHr is activated in the presence of TSH, while it is inhibited following DDT exposure. DDT can also reduce the endocytic vesicular traffic, alter the extension of multi-branched microvilli along their plasma membranes and induce TSHr shedding in vesicular forms. To verify whether TSHr displacement might depend on DDT altering the raft constitution of CHO-TSHr cell membranes the extent of TSHr and lipid raft co-localization was examined by confocal microscopy. Evidence shows that receptor/raft co-localization increased significantly upon exposure to TSH, while receptors and lipid rafts become dislodged on opposite cell poles in DDT-exposed CHO-TSHr cells. As a control, under similar culturing conditions, diphenylethylene, which is known to be a lipophilic substance that is structurally related to DDT, did not affect the extent of TSHr and lipid raft co-localization in CHO-TSHr cells treated with TSH. These findings corroborate and extend our view that, in CHO cells, the DDT disrupting action on TSHr is primarily due to the insecticide acting on membranes to deplete their raft cholesterol content, and that the resulting inhibition on TSHr internalization is due to receptor dislodgement from altered raft microdomains of the plasma membrane. - Highlights: >DDT is a pesticide with a severe environmental impact >Epidemiologic correlation exists between exposition to DDT and thyroid dysfunction >DDT is a lipophilic molecule that has been shown to inhibit TSH receptor function >DDT depletes membrane raft cholesterol content and by this way inhibits TSH receptor
De Gregorio, Francesca; Pellegrino, Mario [Department of Physiological Sciences, University of Pisa (Italy); Picchietti, Simona; Belardinelli, Maria C. [Department of Environmental Sciences, Tuscia University, Viterbo (Italy); Taddei, Anna Rita [Interdepartmental Centre for Electron Microscopy, Tuscia University, Viterbo (Italy); Fausto, Anna Maria [Department of Environmental Sciences, Tuscia University, Viterbo (Italy); Rossi, Mario [Department of Experimental Medicine, University of L'Aquila, L'Aquila (Italy); Maggio, Roberto, E-mail: email@example.com [Department of Experimental Medicine, University of L'Aquila, L'Aquila (Italy); Giorgi, Franco [Department of Neuroscience, University of Pisa, Pisa (Italy)
Induction and Persistence of Large ?H2AX Foci by High Linear Energy Transfer Radiation in DNA-Dependent protein kinaseDeficient Cells
Purpose: To evaluate the cell response to DNA double-strand breaks induced by low and high linear energy transfer (LET) radiations when the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs), an essential protein of the nonhomologous end-joining repair pathway, lacks kinase activity. Methods and Materials: CHO10B2, a Chinese hamster ovary cell line, and its derived radiosensitive mutant cell line, irs-20, lacking DNA-PKcs activity, were evaluated after 0 to 3 Gy of ?-rays, plateau and Bragg peak protons, and lithium beams by clonogenic assay, and as a measurement of double-strand breaks, phosphorylated H2AX (?H2AX) foci number and size were quantified by immunocytofluorescence. Results: Irs-20 exhibited greater radiosensitivity and a higher amount of ?H2AX foci than CHO10B2 at 6 hours after irradiation for all types of radiations. Remarkably, CHO10B2 and irs-20 maintained their difference in radiosensitivity after high-LET radiation. Six hours after low-LET radiations, irs-20 did not reach basal levels of ?H2AX at high doses, whereas CHO10B2 recovered basal levels for all doses. After high-LET radiation, only CHO10B2 exhibited a reduction in ?H2AX foci, but it never reached basal levels. Persistent foci in irs-20 confirmed a repair deficiency. Interestingly, after 30 minutes of high-LET radiation both cell lines exhibited large foci (size >0.9 ?m{sup 2}) related to the damage nature, whereas at 6 hours irs-20 showed a higher amount of large foci than CHO10B2, with a 7-fold increase at 3 Gy, that could also be associated to radiosensitivity. Conclusions: We demonstrated, for the first time, an association between deficient DNA-PKcs activity and not only high levels of H2AX phosphorylation but also persistence and size increase of ?H2AX foci after high-LET irradiation.
Bracalente, Candelaria; Ibaþez, Irene L. [Departamento de Micro y NanotecnologÚa, Comisiµn Nacional de EnergÚa Atµmica, San MartÚn, Buenos Aires (Argentina); Consejo Nacional de Investigaciones CientÚficas y TÕcnicas, Buenos Aires (Argentina); Molinari, Beatriz [Departamento de RadiobiologÚa, Comisiµn Nacional de EnergÚa Atµmica, San MartÚn, Buenos Aires (Argentina); Consejo Nacional de Investigaciones CientÚficas y TÕcnicas, Buenos Aires (Argentina); Palmieri, Mµnica [Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires (Argentina); Kreiner, AndrÕs [Consejo Nacional de Investigaciones CientÚficas y TÕcnicas, Buenos Aires (Argentina); Gerencia de Investigaciµn y Aplicaciones, Comisiµn Nacional de EnergÚa Atµmica, San MartÚn, Buenos Aires (Argentina); Escuela de Ciencia y TecnologÚa, Universidad Nacional de San MartÚn, San MartÚn, Buenos Aires (Argentina); Valda, Alejandro [Escuela de Ciencia y TecnologÚa, Universidad Nacional de San MartÚn, San MartÚn, Buenos Aires (Argentina); and others
Investigations on the control of the sorghum midge: Contarinia sorghicola (Coquillett) by the use of insecticides and resistant varieties.
txaated fo& r Gogo cfear r&~ of hcnde h?d' el&&OX, . ' ad fX 9&3 tha h&agt ~ 4 00 ~ ~ ~ ~ ~ ~ 4 ~ 0 4 ~ 0 4 ~ 4 ~ 40 ~ ~ 0 ~ ~ ~ ~ ~ 4 ~ 4 ~ 3Q '&coul t&l of in-eeticide tr&fst:. ants far the control of the Serf&;hun oid, . -e an;. ;r&. . '& oor?huxf pl... on Cno Qntoae [!83' Q Gnd ilap e. ke lij60e bnn6Q On Cho av~ er;=, . 8 nnmbar Of aiQge that emerged frOm fiVO haaQO ~ ~ eo $1 , 1/a Coivehrison of 1g vnrietiea of grain' ooxppna CO at taa~w hp 'eho aorghun mid, ?"6 in Cho fielde Data h:-QOQ 'On a...
Doering, George William
Search for B???(?)? and B?e?(e)?
,20 J. Gronberg,21 C. M. Korte,21 D. J. Lange,21 R. Kutschke,21 S. Menary,21 R. J. Morrison,21 S. Nakanishi,21 H. N. Nelson,21 T. K. Nelson,21 C. Qiao,21 J. D. Richman,21 D. Roberts,21 A. Ryd,21 H. Tajima,21 M. S. Witherell,21 R. Balest,22 B. H.... Behrens,22 K. Cho,22 W. T. Ford,22 H. Park,22 P. Rankin,22 J. Roy,22 J. G. Smith,22 J. P. Alexander,23 C. Bebek,23 B. E. Berger,23 K. Berkelman,23 K. Bloom,23 D. G. Cassel,23 H. A. Cho,23 D. M. Coffman,23 D. S. Crowcroft,23 M. Dickson,23 P. S. Drell,23 R...
Baringer, Philip S.
Part I. Approaches Toward the Total Synthesis of Tyloindicine F; Part II. Palladium-Catalyzed C?H Functionalization of ?-enaminones
of starting materials and reviewing literature examples (Scheme 2.3). 82 35 Scheme 2.3 OMe Me CHO CO 2 H MeO + OMe Me CO 2 H MeO OMe Me R Me Ac 2 O, TEA 60% DIBAL-H, RT 84% I-01 OMe Me CO 2 Me MeO SOCl 2 , MeOH 95% I-02 I-03 R =CH 2 I-04 O MnO 2... with the desired aldehyde. Scheme 2.4 OMe MeO CHO MeO 1. EDCI, NM, HNMe(Oe) . HCl 2. IBAL-, -78 ? OMe MeO CO 2 MeO I-01 I-04 37 22.214.171.124. Determination of the cis Conformation of the Perkin Product Several grams of aldehyde I-04 were prepared using...
Bi, Lei
Thng 9, 2010 Xut bn bi Office of International Affairs
Loan, ûÈ thûÇng bûÀo cûÀc chng trû˜nh û o to cp bng cht lng cao vi chi phûÙ hp lû§ (khong t 3200~4500 USD mt nm cht lng. Bûˆn cnh cûÀc chng trû˜nh cp bng, NTU cûýn cû° 2 trung tûÂm ngoi ng tuyt vi cho nhng ai thûÙch thû¤.v...) c trao cho cûÀc sinh viûˆn t yûˆu cu cht lng. Bûˆn cnh cûÀc chng trû˜nh cp bng, NTU cûýn cû° 2 trung tûÂm
Wu, Yih-Min
Kh trng khn cp nc ung Trong nhng thi k ri ren, cc s y t a phng c th khuyn co ngi dn dng nc thn
nc cho gia û˜nh bn, bn vn cû° th tû˜m c s lng gii hn dû¿ng bng cûÀch ly nc ra t bû˜nh nc nû°ng, hay lû tan nc ni û°. Thuc kh trû¿ng ûÙt hiu nghim nu nc c. Cn phi lc nc c qua nhng khn sch hoc yûˆn cho lng xung, vû khûÇng b r sûˋt. Cû° hai phng phûÀp kh trû¿ng thûÇng dng vû hiu qu nu lng nc ûÙt. Phng phûÀp th nht lû ûun
Hydrogenation at low temperatures does not always lead to saturation: the case of HNCO
Context. It is generally agreed that hydrogenation reactions dominate chemistry on grain surfaces in cold, dense molecular cores, saturating the molecules present in ice mantles. Aims. We present a study of the low temperature reactivity of solid phase isocyanic acid (HNCO) with hydrogen atoms, with the aim of elucidating its reaction network. Methods. Fourier transform infrared spectroscopy and mass spectrometry were employed to follow the evolution of pure HNCO ice during bombardment with H atoms. Both multilayer and monolayer regimes were investigated. Results. The hydrogenation of HNCO does not produce detectable amounts of formamide (NH2CHO) as the major product. Experiments using deuterium reveal that deuteration of solid HNCO occurs rapidly, probably via cyclic reaction paths regenerating HNCO. Chemical desorption during these reaction cycles leads to loss of HNCO from the surface. Conclusions. It is unlikely that significant quantities of NH2CHO form from HNCO. In dense regions, however, deuteration o...
Noble, J A; Congiu, E; Dulieu, F; Bonnin, M; Bassas, A; Duvernay, F; Danger, G; Chiavassa, T
Tonton Liben
petÒt ki fÒ ti mesye yo pa t cho men 1 1 nan jwÒt doinino a. Se konsa, kou b¶s D¶ parÒt, yo tout vire do kite jwÒt la, epi yo fann nan siyay li. Sa ki te pi cho nan ko tonton an5 di konsa: "B¶s D¶ o!... 5 Kote ou bare ak gwo tchwe lanp sa a?...6... GenlÒ ou frÒt aswÒ a?" Yo pa menm bay tonton an tan pou I rekonÒt li, pase yon lot di konsa: "Pa pito ou vin kraze kÒk lodyans ak nou, poko gen moun ki 10 konprann anyen nan veye sa a."7 Gen yon twazyÒm ki te chita jouk byen Iwen, li leve kanpe...
Paultre, Carrie?; Freeman, Bryant C.
Prolactin receptor and signal transduction to milk protein genes
After cloning of the mammary gland prolactin (PRL) receptor cDNA, a functional assay was established using co-transfection of PRL receptor cDNA together with a milk protein promoter/chloramphenicol acetyl transferase (CAT) construct in Chinese hamster ovary (CHO) cells. Different mutants of the PRL receptor were tested in this CAT assay to delimit the domains in the receptor necessary for signal transduction to milk protein genes. In CHO cells stably transfected with PRL receptor cDNA, high numbers of PRL receptor are expressed. By metabolic labeling and immunoprecipitation, expressed PRL receptor was identified as a single species of 100 kDa. Using these cells, we analyzed the effects of PRL on intracellular free Ca{sup ++} concentration. PRL stimulates Ca{sup ++} entry and induces secondary Ca{sup ++} mobilization. The entry of Ca{sup ++} is a result of an increase in K{sup +} conductance that hyperpolarizes the membranes. We have also analyzed tyrosine phosphorylation induced by PRL. In CHO cells stably transfected with PRL receptor cDNA, PRL induced a very rapid and transient tyrosine phosphorylation of a 100-kDa protein which is most probably the PRL receptor. The same finding was obtained in mammary membranes after PRL injection to lactating rabbits. Whereas tyrosine kinase inhibitors genistein and lavendustin were without effect, PRL stimulation of milk protein gene promoters was partially inhibited by 2 {mu}M herbimycin in CHO cells co-transfected with PRL receptor cDNA and the {Beta} lactoglobulin CAT construct. Taken together these observations indicate that the cytoplasmic domain of the PRL receptor interacts with one or several tyrosine kinases, which may represent early postreceptor events necessary for PRL signal transduction to milk protein genes. 14 refs., 4 figs.
Djiane, J.; Daniel, N.; Bignon, C. [Unite d`Endocrinologie Moleculaire, Jouy en Josas (France)] [and others
Application of fundamental kinetic modeling to industrial chlorination and partial oxidation processes
. 745 74. 796 71. 942 73. 792 74. 841 76. 423 80. 223 78. 535 Table g. Calculated Coefficients for Specific Heat in Eq. 3 A B C D CHB-OOH CHs-C=OOOH CHs-CHsOOH CHs-OO-CHs CHs-C=O-CHO C Hs-C=O-C HtO H CHs-C=O-C=O-CHs CH, -CH, -C=O-CHs 1...
Han, Joseph Hsiao-Tien
Burrito:Eggs,Cheese,inawrap (2CHO) TurkeySausage Cereals(1CHOEACH) RiceKrispies SpecialK Cheerios CreamofWheat Breakfast/LowfatItalian/LowfatFrench) DESSERTS:(Limit2,1mustbefruit) (1CHOEACH) AngelFoodCakeDietGelatin(free) Diet/Ranch/French/Caesar/Oil& Vinegar/LowfatItalian/LowfatFrench) DESSERTS:(Limit2,1mustbefruit) (1CHOEACH) Angel
Google:[Leonid Zakharov] http://w3.pppl.gov/~zakharov LiWF & Spherical Tokamaks
, ASIPP July 09, 2008, Hefei, Ahnui, China 1 This work is supported by US DoE contract No. DEôÙAC020ôÙ76ôÙCHO, was introduced. In the LiWF regime the temperature pedestal is equal to core temperature. At the same time 11111111 1111 1111 1111 11111111 Plasma core Confinement zone Free flow zone ion ion core-edge electron
Journal of The Korean Astronomical Society 37: 55 59, 2004
ôÇenic wave supply solar wind energy. Tu & Marsch (1997) further developed a two fluid solar wind model from SOLAR WIND MODEL S.-J. Kim 1,2 , K.-S. Kim2 , Y.-J. Moon1 , K.-S. Cho1 , AND Y. D. Park1,3 1 Korea North Shore Lane, Big Bear City, CA 92314, USA (Received March 13, 2004; Accepted March 19, 2004
(Perturbational) @bi.snu.ac.kr firstname.lastname@example.com
. [5] Eisen, M.B., Spellman, P.T., Brown, P.O., and Botstein, D., Cluster analysis and display. 407, p. 651, 2000. [7] Tavazoie, S., Huges, J.D., Campbell, M.J., Cho, R.J., and Church, G Wide Web, Science, vol. 287, p. 2115a, 2000. [4] DeRisi, J.L., Iyer, V.R., and Brown, P.O., Exploring
(E)-4-[(4-nitrophenyl)diazenyl]phenyl anthracene-9-carboxylate.
In the title compound, C{sub 27}H{sub 17}N{sub 3}O{sub 4}, the azo group displays a trans conformation and the dihedral angles between the central benzene ring and the pendant anthracene and nitrobenzene rings are 82.94 (7) and 7.30 (9){sup o}, respectively. In the crystal structure, weak C-H...O hydrogen bonds, likely associated with a dipole moment present on the molecule, help to consolidate the packing.
Vance, Andrew L. (Sandia National Laboratories, Livermore, CA); Zifer, Thomas (Sandia National Laboratories, Livermore, CA); Nichol, Jessica L. (Sandia National Laboratories, Livermore, CA); Rodriguez, Mark Andrew; Leonard, Francois Leonard (Sandia National Laboratories, Livermore, CA); Wong, Bryan Matthew (Sandia National Laboratories, Livermore, CA)
Functionalized polyfluorenes for use in optoelectronic devices
The present invention relates to process comprising reacting a polyfluorenes comprising at least one structural group of formula I ##STR00001## with an iridium (III) compound of formula II ##STR00002## wherein R.sup.1 and R.sup.2 are independently alkyl, substituted alkyl, aryl, substituted aryl or a combination thereof; R.sup.5is H or CHO; R.sup.3 and R.sup.4 are independently hydrogen, alkyl, substituted alkyl, aryl, substituted aryl or a combination thereof; R.sup.11 and R.sup.12 taken together form a substituted or unsubstituted monocyclic or bicyclic heteroaromatic ring; R.sup.13 is independently at each occurrence halo, nitro, hydroxy, amino, alkyl, aryl, arylalkyl, alkoxy, substituted alkoxy, substituted alkyl, substituted aryl, or substituted arylalkyl; Ar is aryl, heteroaryl, substituted aryl, substituted heteroaryl, or a combination thereof; X is selected from a direct bond, alky, substituted alkyl, and combinations thereof; Y is CHO or NH.sub.2; Z is CHO or NH.sub.2 where Z does not equal Y; and p is 0, 1 or 2. The invention also relates to the polyfluorenes, which are products of the reaction, and the use of the polyfluorenes in optoelectronic devices.
Chichak, Kelly Scott (Clifton Park, NY); Lewis, Larry Neil (Scotia, NY); Cella, James Anthony (Clifton Park, NY); Shiang, Joseph John (Niskayuna, NY)
Mapping analysis of scaffold/matrix attachment regions (s/MARs) from two different mammalian cell lines
Scaffold/matrix attachment regions (S/MARs) are potential element that can be integrated into expression vector to increase expression of recombinant protein. Many studies on S/MAR have been done but none has revealed the distribution of S/MAR in a genome. In this study, we have isolated S/MAR sequences from HEK293 and Chinese hamster ovary cell lines (CHO DG44) using two different methods utilizing 2 M NaCl and lithium-3,5-diiodosalicylate (LIS). The isolated S/MARs were sequenced using Next Generation Sequencing (NGS) platform. Based on reference mapping analysis against human genome database, a total of 8,994,856 and 8,412,672 contigs of S/MAR sequences were retrieved from 2M NaCl and LIS extraction of HEK293 respectively. On the other hand, reference mapping analysis of S/MAR derived from CHO DG44 against our own CHO DG44 database have generated a total of 7,204,348 and 4,672,913 contigs from 2 M NaCl and LIS extraction method respectively.
Pilus, Nur Shazwani Mohd; Ahmad, Azrin; Yusof, Nurul Yuziana Mohd [School of Bioscience and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia); Johari, Norazfa [Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia)
Cardiac catecholamines in rats fed copper deficient or copper adequate diets containing fructose or starch
The symptoms of copper (Cu) deficiency are known to be more severe when rats are fed a diet with fructose (F) as the principal carbohydrate. Mortality, in males, due to cardiac abnormalities usually occurs after five weeks of a 62% F, 0.6 ppm Cu deficient diet. These effects are not observed if cornstarch (CS) is the carbohydrate (CHO) source. Studies with F containing diets have shown increased catecholamine (C) turnover rates while diets deficient in Cu result in decreased norepinephrine (N) levels in tissues. Dopamine B-hydroxylase (EC 18.104.22.168) is a Cu dependent enzyme which catalyzes the conversion of dopamine (D) to N. An experiment was designed to investigate the effects of CHO and dietary Cu on levels of three C in cardiac tissue. Thirty-two male and female Sprague-Dawley rats were fed Cu deficient or adequate diets with 60% of calories from F or CS for 6 weeks. N, epinephrine (E) and D were measured by HPLC. Statistical analysis indicates that Cu deficiency tends to decrease N levels, while having the reverse effect on E. D did not appear to change. These findings indicate that Cu deficiency but not dietary CHO can affect the concentration of N and E in rat cardiac tissue.
Scholfield, D.J.; Fields, M.; Beal, T.; Lewis, C.G.; Behall, K.M. (Dept. og Agriculture, Beltsville, MD (USA))
Staff in the Division of New Reactor Licensing (DNRL) requested assistance from the Division of Waste Management and Environmental Protection (DWMEP) in the development of a standard review plan (SRP) for the licensing of new reactor facilities. Specifically, DNRL staff requested a list of high-level decommissioning lessons-learned that new applicants for a reactor license should address in order to minimize, to the extent practicable, contamination of the facility and the environment, facilitate eventual decommissioning, and minimize, to the extent practicable, the generation of radioactive waste. DWMEP staff met with your staff several times to discuss and clarify the requested input. This requested information is provided in Enclosure 1. I would like to bring to your attention other sources of decommissioning lessons-learned. The list of lessons-learned provided in Enclosure 1 is a subset of a much larger set of decommissioning lessons-learned. DWMEP developed the list in Enclosure 1 by reviewing the lessons-learned described in other documents (Enclosure 2) and selecting those it felt were most significant, based on DWMEP decommissioning experience. Additionally, the Electric Power Research Institute (EPRI) has developed decommissioning lessons-learned. DWMEP has not reviewed those lessons-learned because they are considered proprietary information by EPRI. DWMEP staff also developed a comprehensive bibliography of documents containing decommissioning lessons-learned. The bibliography is posted on the Nuclear Regulatory Commissions public website. CONTACT: Rafael L. Rodriguez, NMSS/DWMEP
Memorandum To; David B. Matthews; Elmo E. Collins
Testing of Crystallization Temperature of a New Working Fluid for Absorption Heat Pump Systems
Lithium bromide/water (LiBr/water) absorption systems are potential candidates for absorption heat pump water heating applications since they have been widely commercialized for cooling applications. One drawback to LiBr/water absorption water heater systems is that they are unable to operate at typical water heating temperatures due to solution crystallization hazards. Binary or ternary mixtures, serving as working fluids, were reported (Ally, 1988; Herold et al., 1991; Iyoki and Uemura, 1981; Yasuhide Nemoto et al., 2010; Zogg et al., 2005) to help improve the absorption performance or avoid crystallization of absorption heat pump systems. A recent development (De Lucas et al., 2007) investigated the use of a ternary mixture of aqueous mixture of lithium bromide and sodium formate (CHO2Na). The new working fluid composition maintains a ratio of LiBr/CHO2Na of 2 by weight. This new working fluid is a potential competitor to aqueous LiBr solution in absorption system due to higher water vapor absorption rates and lower generation temperature needed (De Lucas et al., 2004). There exists data on equilibrium performance and other physical properties of this new working fluid. However, there is no available data on crystallization behavior. Crystallization temperature is crucial for the design of absorption heat pump water heater in order to avoid crystallization hazards during operation. We have therefore conducted a systematic study to explore the crystallization temperature of LiBr/CHO2Na water solution and compared it against aqueous LiBr solutions. These results were then used to evaluate the feasibility of using the new working fluid in water heating applications showing limited potential.
Wang, Kai [ORNL] [ORNL; Kisari, Padmaja [ORNL] [ORNL; Abdelaziz, Omar [ORNL] [ORNL; Vineyard, Edward Allan [ORNL] [ORNL
Angular dependence of metamagnetic transitions in DyAgSb2
and 2n neighbors arise in the nth term of the high- 1 P. C. Canfield, S. L. Bud?ko, B. K. Cho, A. Lacerda, D. Farrell, E. Johnston-Halperin, V. A. Kalatsky, and V. L. Pokrovsky, Phys. Rev. B 55, 970 ~1997!. 2 V. A. Kalatsky and V. L. Pokrovsky, Phys.... Rev. B 57, 5485 ~1998!. 3 P. C. Canfield and S. L. Bud?ko, J. Alloys Compd. 262-263, 169 ~1997!. 4 S. L. Bud?ko, P. C. Canfield, C. H. Mielke, and A. H. Lacerda, Phys. Rev. B 57, 13 624 ~1998!. 5 R. Wang and H. Steinfink, Inorg. Chem. 6, 1685...
Myers, KD; Canfield, PC; Kalatsky, VA; Pokrovsky, Valery L.
Further trials with partial penetrating keratoplasty in dogs
l gieataon crossbred~ clinicaLLy healthy adult nolo scd fcnala dogs~ ?cguirod fran tho ihsnicipaL pound& ?ere use4 in this superi?ant. The aninals wave divided in Cwo groups& a) pilot aninalc an4 b) gxperincncal cain?Ls. group a) consisted...-co-border encores wean append at 0'~ p0, 180 ~ sn4 270 using Cho Cwo double essed 4~0 silk notarial (Fig. 4a), The needles perforated the cornea approximately 0. 5 wa fraa the wargin of tho trephine suc snd inslude4 two thirds of its tbiekaass (Fig. 4b). 4...
Bernis, Walter Octaviano
Synthesis and crystal structure studies of ethyl 5-methyl-1, 3-diphenyl-1H-pyrazole-4-carboxylate
The title compound, C{sub 19}H{sub 18}N{sub 2}O{sub 2}, was investigated by single crystal X-ray diffraction method. It crystallizes in monoclinic class under the space group P2{sub 1}/c with cell parameters a= 8.4593(4) é, b=15.6284(6) é, c=12.4579(5) é, ?=90¯, ?=98.241(3)¯, ?=90¯ and Z=2. The ethoxycarbonyl group is slightly twisted from the pyrazole ring, and adopts syn-periplanar conformation. The crystal structure is stabilized by intermolecular C-H
.O hydrogen bonds, which help in stabilizing the crystal structure.
Chandra,; Babu, E. A. Jithesh; Mahendra, M., E-mail: firstname.lastname@example.com [Department of Studies in Physics, Manasagangotri, University of Mysore, Mysore-570006 (India); Srikantamurthy, N.; Umesha, K. B. [Department of Chemistry, Yuvaraja's College, University of Mysore, Mysore-570005 (India)
Studies towards the total synthesis of the macrocyclic diamine alkaloid haliclonacyclamine C
(1.9) N N H O manzamine C (1.10) N N H N Figure 2 Structures of manzamines A-C Manzamine C (1.10), the least complicated alkaloid of this group, can be reduced to four simple units, tryptophan (1.11), a C3 unit (acrolein) (1.12), a C10 unit (a... HO 2 C NH 2 CHOCHO NH 3 CHO 1.11 1.12 1.13 The biosynthesis of manzamine B (1.10) is likely to start with protonation of bis- dihydropyridine (1.14), derived from two acrolein units (1.12), two symmetrical dialdehyde units (1...
Qu, Tao
Location of marker genes on definite chromosomes of Gossypium hirsutum L
ratios of the various factors, both in the ~1's and in ths eelfa, were st~ died for Che possi- bility of linkag? of one or r~e genes with an intex change colhplexo The Pl orosses and selfs wexo made in the green? hous?at Cho Beasley Laboratory durir...O pxogeny rows including selfed plants wexe available for study during the sum-. . . or of 1~ The technique employed tc detect linkage of one or more genes with an interchange complex may be more easily understood by following the diagrams in Plgures 1...
Abedi, Mohammad Dgavad
A study of the effect of temperature on the rate of settling of crude cotton-seed oil
I, Coaoeraing psntoscLn?, Hank ?rites ae follove& Peatooane Iield yeatoees oa hydrolyaia. So fnr ao ie laaoea they 4o not oscar in the eninLL hingdcse, Thwf havoc hoeover, a very wide die- bribatioa in tho vegetable hingdoa being present Serntheonc Tengboo3... olaselp related to each other end to aeccrine (the taxis ytcnmaiae) ia oeapesxtioa aad strsetero~ ChoVne an4 betaine aro noa toxcLe and oftea oscar together ia the @orms of xaxO pleats+ hp eem investigators thcO are regarded ae the iaterss- 4iate...
Jeffrey, Jack Cassels
K. Toyota et al.: Photochemistry of VOCs and halogens in the MBL (Supplement) 1 A supplement to "A box model study on photochemical interactions
/used in the present work. S1 C2H4 degradation initiated by Cl atoms The reaction between Cl atoms and C2H4 for UV-irradiated Cl2/C2H4/air mixtures have identified ClCH2CHO, ClCH2CH2OOH, and ClCH2CH2OH as main degradation products (Walling- ton et al., 1990; Yarwood et al., 1992). This implies that ClCH2CH2OO formed
Meskhidze, Nicholas
Fire, Sacrifice, and Social Change: The Rhetoric of Self-Immolation
-destruction in the western world, but is much more common in Asia most likely due to its ties to Buddhist rituals or self-incineration.64 This has been evidenced in several case studies. For example, in his analysis of the self-immolation of a Korean named Chun Tae-il, Cho... argued that Tae-ils death had considerable influence.65 Specifically, Tae-ils death resonated with many other poor workers who began their own protests after his sacrifice.66 16 Foon Rhee explained that self-immolation was a powerful tool used...
Neville-Shepard, Meredith Diane
A fractal approach to the rheology of concentrated cell suspensions
Results on the rheological behavior of novel CHO cell suspensions in a large range of concentrations are reported. The concentration dependent yield stress and elastic plateau modulus are formalized in the context of fractal aggregates under shear, and quite different exponents are found as compared to the case of red blood cell suspensions. This is explained in terms of intrinsic microscopic parameters such as the cell-cell adhesion energy and cell elasticity but also the cell individual dynamic properties, found to correlate well with viscoelastic data at large concentrations (phi>0.5).
Andreea Iordan; Alain Duperray; Claude Verdier
Methodology for Analyzing Energy and Demand Savings From Energy Services Performance Contract Using Short-Term Data
..iilJlf t '_:pUIltaD ? (e) (d) ? ? I I , , ., ? BJ ? AmmJl.thm:pIIILt1II:l ....iind?t.m'.m1R.Dl (,) (f) r ~ ~, ~I-----------'l,----------f .. AmmJl.thJII.:p1mt1ll:1 ., February 9, 2009 Energy Systems Laboratory 10 CONCLUSIONSCASE STUDIESMETHODOLOGY DEMAND SAVINGS...METHODOLOGY FOR ANALYZING ENERGY AND DEMAND SAVINGS FROM ENERGY SERVICES PERFORMANCE CONTRACT USING SHORT-TERM DATA Zi Liu, Jeff Haberl, Soolyeon Cho Energy Systems Laboratory Texas A&M University System College Station, TX 77843 Bobby...
Liu, Z.; Haberl, J. S.; Cho, S.; Lynn, B.; Cook, M.
Search for R-parity violation in multilepton final states in pp-bar collisions at s?=1.8?TeV
. We consider the selection criteria of Ref. @3# adequate for the present analysis. Our search is most sensitive to decays with highest elec- tron and muon multiplicity, i.e., those with no t lepton among the decay products of the LSP. The detection.... Buchholz,34 M. Buehler,32 V. Buescher,49 V. S. Burtovoi,21 J. M. Butler,42 F. Canelli,49 W. Carvalho,3 D. Casey,45 Z. Casilum,50 H. Castilla-Valdez,17 D. Chakraborty,50 K. M. Chan,49 S. V. Chekulaev,21 D. K. Cho,49 S. Choi,28 S. Chopra,51 B. C. Choudhary,28...
Baringer, Philip S.; Bean, Alice; Coppage, Don; Hebert, C.; Abbott, B.; Abolins, M.; Abramov, V.; Acharya, B. S.; Adams, D. L.; Adams, M.
Development of a High-Performance Office Building Simulation Model for a Hot and Humid Climate
48% total energy savings above the ASHRAE 90.1-1999 code and 61% savings when compared to the calibrated simulation model of the case-study building. The results show that substantial energy savings can be achieved only by using common... to the field measured data and was presented in the previous publication (Cho and Haberl, 2008a). The calibrated simulation model was further extended to an ASHRAE 90.1 code-compliant model, which was used as the baseline model for the development of a...
Ionothermal Synthesis and Magnetic Studies of Novel Two-Dimensional Metal-Formate Frameworks
Five novel two-dimensional frameworks containing formate-bridged metal-centered octahedra are synthesized ionothermally from two ionic liquids previously unused as solvents in hybrid synthesis, 2-hydroxyethylammonium (HEA) formate, and 1-hydroxy-3-proplyammonium (HPA) formate. Templating effects of the cation from each ionic liquid drive the formation of different structures. [NH{sub 3}C{sub 2}H{sub 4}OH]{sub 2}[M(CHO{sub 2}){sub 4}] (1: M = Co, 2: M = Ni) exhibit the same stoichiometry and connectivity as their manganese analogue (3: M = Mn), but the manganese form exhibits a different topology from 1 and 2. [NH{sub 3}C{sub 3}H6OH][M(CHO{sub 2}){sub 3}(H{sub 2}O)] (4: M = Co, 5: M = Mn) were synthesized using the HPA formate ionic liquid with a metal-formate connectivity related to those of 1-3. Canted antiferromagnetic ordering occurs at low temperatures (1: T{sub N} = 7.0 K, 2: T{sub N} = 4.6 K, 3: T{sub N} = 8.0 K, 4: T{sub N} = 7.0 K, 5: T{sub N} = 9.2 K), similar to the magnetic properties previously reported for other metal-formate hybrid materials.
Calderone, P.; Feygenson, M.; Forster, P.M.; Borkowski, L.A.; Teat, S.J. Aronson, M.C.; Parise, J.B.
Search for methylamine in high mass hot cores
We aim to detect methylamine, CH$_{3}$NH$_{2}$, in a variety of hot cores and use it as a test for the importance of photon-induced chemistry in ice mantles and mobility of radicals. Specifically, CH$_3$NH$_2$ cannot be formed from atom addition to CO whereas other NH$_2$-containing molecules such as formamide, NH$_2$CHO, can. Submillimeter spectra of several massive hot core regions were taken with the James Clerk Maxwell Telescope. Abundances are determined with the rotational diagram method where possible. Methylamine is not detected, giving upper limit column densities between 1.9 $-$ 6.4 $\\times$ 10$^{16}$ cm$^{-2}$ for source sizes corresponding to the 100 K envelope radius. Combined with previously obtained JCMT data analyzed in the same way, abundance ratios of CH$_{3}$NH$_{2}$, NH$_{2}$CHO and CH$_{3}$CN with respect to each other and to CH$_{3}$OH are determined. These ratios are compared with Sagittarius B2 observations, where all species are detected, and to hot core models. The observed ratios su...
Ligterink, N F W; van Dishoeck, E F
Tumor Metabolism and Perfusion in Head and Neck Squamous Cell Carcinoma: Pretreatment Multimodality Imaging With {sup 1}H Magnetic Resonance Spectroscopy, Dynamic Contrast-Enhanced MRI, and [{sup 18}F]FDG-PET
Purpose: To correlate proton magnetic resonance spectroscopy ({sup 1}H-MRS), dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and {sup 18}F-labeled fluorodeoxyglucose positron emission tomography ([{sup 18}F]FDG PET) of nodal metastases in patients with head and neck squamous cell carcinoma (HNSCC) for assessment of tumor biology. Additionally, pretreatment multimodality imaging was evaluated for its efficacy in predicting short-term response to treatment. Methods and Materials: Metastatic neck nodes were imaged with {sup 1}H-MRS, DCE-MRI, and [{sup 18}F]FDG PET in 16 patients with newly diagnosed HNSCC, before treatment. Short-term patient radiological response was evaluated at 3 to 4 months. Correlations among {sup 1}H-MRS (choline concentration relative to water [Cho/W]), DCE-MRI (volume transfer constant [K{sup trans}]; volume fraction of the extravascular extracellular space [v{sub e}]; and redistribution rate constant [k{sub ep}]), and [{sup 18}F]FDG PET (standard uptake value [SUV] and total lesion glycolysis [TLG]) were calculated using nonparametric Spearman rank correlation. To predict short-term responses, logistic regression analysis was performed. Results: A significant positive correlation was found between Cho/W and TLG ({rho} = 0.599; p = 0.031). Cho/W correlated negatively with heterogeneity measures of standard deviation std(v{sub e}) ({rho} = -0.691; p = 0.004) and std(k{sub ep}) ({rho} = -0.704; p = 0.003). Maximum SUV (SUVmax) values correlated strongly with MRI tumor volume ({rho} = 0.643; p = 0.007). Logistic regression indicated that std(K{sup trans}) and SUVmean were significant predictors of short-term response (p < 0.07). Conclusion: Pretreatment multimodality imaging using {sup 1}H-MRS, DCE-MRI, and [{sup 18}F]FDG PET is feasible in HNSCC patients with nodal metastases. Additionally, combined DCE-MRI and [{sup 18}F]FDG PET parameters were predictive of short-term response to treatment.
Jansen, Jacobus F.A. [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Department of Radiology, Maastricht University Medical Center, Maastricht (Netherlands); Schoeder, Heiko [Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Lee, Nancy Y. [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Stambuk, Hilda E. [Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Wang Ya [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Fury, Matthew G. [Department of Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Patel, Senehal G. [Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Pfister, David G. [Department of Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Shah, Jatin P. [Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Koutcher, Jason A. [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Department of Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Shukla-Dave, Amita, E-mail: firstname.lastname@example.com [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)
Thermochemical Insight into the Reduction of CO to CH3OH with [Re(CO)]+ and [Mn(CO)]+ Complexes
To gain insight into thermodynamic barriers for reduction of CO into CH3OH, free energies for reduction of [CpRe(PPh3)(NO)(CO)]+ into CpRe(PPh3)(NO)(CH2OH) have been determined from experimental measurements. Using model complexes, the free energies for the transfer of H+, H, and e have been determined. A pKa of 10.6 was estimated for [CpRe(PPh3)(NO)(CHOH)]+ by measuring the pKa for the analogous [CpRe(PPh3)(NO)(CMeOH)]+. The hydride donor ability (?G¯H) of CpRe(PPh3)(NO)(CH2OH) was estimated to be 58.0 kcal mol1, based on calorimetry measurements of the hydride transfer reaction between CpRe(PPh3)(NO)(CHO) and [CpRe(PPh3)(NO)(CHOMe)]+ to generate the methylated analog, CpRe(PPh3)(NO)(CH2OMe). Cyclic voltammograms recorded on CpRe(PPh3)(NO)(CMeO), CpRe(PPh3)(NO)(CH2OMe), and [CpRe(PPh3)(NO)(CHOMe)]+ displayed either a quasireversible oxidation (neutral species) or reduction (cationic species). These potentials were used as estimates for the oxidation of CpRe(PPh3)(NO)(CHO) or CpRe(PPh3)(NO)(CH2OH), or the reduction of [CpRe(PPh3)(NO)(CHOH)]+. Combination of the thermodynamic data permits construction of three-dimensional free energy landscapes under varying conditions of pH and PH2. The free energy for H2 addition (?G¯H2) to [CpRe(PPh3)(NO)(CO)]+ (+15 kcal mol1) was identified as the most significant thermodynamic impediment for the reduction of CO. DFT computations indicate that ?G¯H2 varies by only 4.3 kcal mol1 across a series of [CpXRe(L)(NO)(CO)]+, while the experimental ?G¯H values for the analogous series of CpRe(PPh3)(NO)(CHO) varies by 12.9 kcal mol1. The small range of ?G¯H2 values is attributed to a minimal change in the CO bond polarization upon modification of the ancillary ligands, as determined from the computed atomic charges. This work was supported by the US Department of Energy, Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences & Biosciences. Pacific Northwest National Laboratory (PNNL) is a multiprogram national laboratory operated for DOE by Battelle.
Wiedner, Eric S.; Appel, Aaron M.
A COLD COMPLEX CHEMISTRY TOWARD THE LOW-MASS PROTOSTAR B1-b: EVIDENCE FOR COMPLEX MOLECULE PRODUCTION IN ICES
Gas-phase complex organic molecules have been detected toward a range of high- and low-mass star-forming regions at abundances which cannot be explained by any known gas-phase chemistry. Recent laboratory experiments show that UV irradiation of CH{sub 3}OH-rich ices may be an important mechanism for producing complex molecules and releasing them into the gas phase. To test this ice formation scenario, we mapped the B1-b dust core and nearby protostar in CH{sub 3}OH gas using the IRAM 30 m telescope to identify locations of efficient non-thermal ice desorption. We find three CH{sub 3}OH abundance peaks tracing two outflows and a quiescent region on the side of the core facing the protostar. The CH{sub 3}OH gas has a rotational temperature of {approx}10 K at all locations. The quiescent CH{sub 3}OH abundance peak and one outflow position were searched for complex molecules. Narrow, 0.6-0.8 km s{sup -1} wide, HCOOCH{sub 3} and CH{sub 3}CHO lines originating in cold gas are clearly detected, CH{sub 3}OCH{sub 3} is tentatively detected, and C{sub 2}H{sub 5}OH and HOCH{sub 2}CHO are undetected toward the quiescent core, while no complex molecular lines were found toward the outflow. The core abundances with respect to CH{sub 3}OH are {approx}2.3% and 1.1% for HCOOCH{sub 3} and CH{sub 3}CHO, respectively, and the upper limits are 0.7%-1.1%, which is similar to most other low-mass sources. The observed complex molecule characteristics toward B1-b and the pre-dominance of HCO-bearing species suggests a cold ice (below 25 K, the sublimation temperature of CO) formation pathway followed by non-thermal desorption through, e.g., UV photons traveling through outflow cavities. The observed complex gas composition together with the lack of any evidence of warm gas-phase chemistry provides clear evidence of efficient complex molecule formation in cold interstellar ices.
Oeberg, Karin I. [Harvard-Smithsonian Center for Astrophysics, MS 42, 60 Garden Street, Cambridge, MA 02138 (United States); Bottinelli, Sandrine [Centre d'Etude Spatiale des Rayonnements, 9 avenue du Colonel Roche, BP 4346, 31028 Toulouse Cedex 4 (France); Joergensen, Jes K. [Centre for Star and Planet Formation, Natural History Museum of Denmark, University of Copenhagen, Oester Voldgade 5-7, 1350 Copenhagen K. (Denmark); Van Dishoeck, Ewine F. [Leiden Observatory, Leiden Sterrewacht, P.O. Box 9513, 2300 RA Leiden (Netherlands)
Measurement of the muon charge asymmetry in pp-bar?W+X???+X events at s?=1.96??TeV
Measurement of the muon charge asymmetry in p #1;p ! W ± X ! #1;#2; ± X events at ffiffi s p ¥ 1:96 TeV V.M. Abazov,31 B. Abbott,66 B. S. Acharya,25 M. Adams,45 T. Adams,43 J. P. Agnew,40 G.D. Alexeev,31 G. Alkhazov,35 A. Alton,55,* A. Askew,43 S.... Brown,14 X. B. Bu,44 M. Buehler,44 V. Buescher,21 V. Bunichev,33 S. Burdin,38, C. P. Buszello,37 E. Camacho-PeÇrez,28 B. C. K. Casey,44 H. Castilla-Valdez,28 S. Caughron,56 S. Chakrabarti,63 K.M. Chan,50 A. Chandra,71 E. Chapon,15 G. Chen,52 S.W. Cho,27...
Baringer, Philip S.; Bean, Alice; Chen, G.; Clutter, Justace Randall; Sekaric, Jadranka; Wilson, Graham Wallace; Abazov, V. M.; Abbott, B.; Acharya, B. S.; Adams, M.; Adams, T.; Agnew, J. P.; Alexeev, G. D.; Alkhazov, G.; Alton, A.; Askew, A.; Atkins, S.
Synthesis and crystal structure of ?,?-unsaturated ketone: 3,3?-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[1-(2-pyridyl) -2-propen-1-one
The title compound, C{sub 30}H{sub 24}N{sub 2}O{sub 4}, 3,3?-[1,2-ethanediyl-bis(oxy-2,1-phenylene)]bis[1-(2-pyridyl) -2-propen-1-one] was synthesized and characterized by elemental analysis, FT-IR spectra, {sup 1}H NMR, and X-ray single-crystal diffraction. In the molecule, the pyridine plane and the adjacent phenyl plane are almost coplanar with the dihedral angle of 3.07¯, while the dihedral angle between the mean planes of the two asymmetric units is 67.56¯. The crystal packing is stabilized by weak intermolecular C-H...N and C-H...O hydrogen bonds, C-H...? and ?...? stacking interactions.
Wang, G.-F., E-mail: firstname.lastname@example.com; Gong, Q.-J., E-mail: email@example.com; Sun, H.; Yao, C-Z. [Yuncheng University, Department of Applied Chemistry (China)
Crystal structure of 4-[benzylideneamino]-3-thiophen-2-yl-methyl-4,5-dihydro-1H-[1,2,4] triazole-5-one
The crystal structure of the title compound C{sub 14}H{sub 12}N{sub 4}OS was determined by the X-ray diffraction method. The compound crystallizes in the triclinic space group P-bar1 with Z = 2. The molecule is not planar: the dihedral angle between the triazole and thiophene rings is 73.98(2)¯, and that between the triazole and benzene rings is 4.05(2)¯. The thiophene ring is disordered over two positions, which are approximately parallel and oppositely oriented. The major component refined to a site-occupancy factor of 0.573(3). An intramolecular C-H...O hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked together by two pairs of N-H...O interactions (to the same O atom as acceptor), forming inversion dimers. The crystal packing is also stabilized by ?-? interactions [centroid-centroid distance is 3.978 é].
Tanak, H., E-mail: email@example.com [Amasya University, Department of Physics, Faculty of Arts and Sciences (Turkey)
TM TT TNG QUAN Vo khong ngy 20 thng 4 nm 2010, n v khoan lu ng ngoi khi Deepwater Horizon, tng
ng phû° vi lng du trû n). Ngoû i ra, hn 1 triu gallon cûÀc cht phûÂn tûÀn ûÈ c dû¿ng cho vû¿ng bin thuc khu vc du trû n nhm phûÂn tûÀn du.1 H qu ca s c trû n du nû y lû mt lng khûÙ gas t nhiûˆn cha nh lng ûÈ thi vû o mûÇi trng. Lc lng Bo v b bin Hoa K ûÈ ng phû° vû ch o cûÀc n lc liûˆn bang nhm ngn chn vû lû m sch du trû n. Phm
nh Gi Thit Hi Ti Nguyn Thin Nhin ca V Trn Du Deepwater Horizon Cc D n Khu Vc
Lng Sûý ip Nhm Tng C Hi ûÀnh Bt Gii TrûÙ Trong Vû¿ng CûÀn Xong Florida s c thc hin Qun Bay (h thng Vnh St Okaloosa vû Walton. Lû§ tng ra thû˜ bng cûÀch thc hin d ûÀn nû y,s lng sûý ip ti cûÀc a im c can thip cui cû¿ng cû° th s tng lûˆn ti cûÀc mc t duy trû˜ bn vng c cho vic ûÀnh bt gii trûÙ. S lng sûý ip cûÀc Qun Gulf vû
M thanh ton 4310-55 [FWS-R4-FHC-2013-N108; [FVHC98130406900-XXX-FF04G01000
lng cha tng cû° du vû thi khûÀc t cûÀc giû n khoan vû t u ging khoan trûˆn ûÀy bin. Deepwater Horizon trû n trû n. Mt s lng cha xûÀc nh khûÙ t nhiûˆn cng c phûÀt hû nh cho mûÇi trng nh lû kt qu ca v trû n du. Ngi c y gian c bn (cht lng vû iu kin cû° th tn ti nu s c trû n du ûÈ khûÇng xy ra tû i nguyûˆn) hoû n tt. Cn c cûÀc
Stable reduction product of misonidazole
The predominant stable product (greater than 80%) of the anaerobic radiation chemical reduction (pH 7, formate, N/sub 2/O) of misonidazole (MISO) has been identified as the cyclic guanidinium ion MISO-DDI, a 4,5-dihydro-4,5-dihydroxyimidazolium ion. This cation was prepared as its sulfate salt by the reaction of glyoxal and the appropriate N-substituted guanidinium sulfate. Its formation during MISO reduction was established by NMR spectral comparison and by derivatization as glyoxal bis-oxime, which was formed in 86% yield in fully reduced systems. The toxicity of pure MISO-DDI X sulfate was examined in vivo (C/sub 3/H mice) and in vitro (CHO cells). This product is less toxic than the parent MISO and free glyoxal. A reactive, short-lived, intermediate is suggested as the agent responsible for the toxicity of MISO under hypoxic conditions.
Panicucci, R.; McClelland, R.A.; Rauth, A.M.
Algorithms for biomagnetic source imaging with prior anatomical and physiological information
This dissertation derives a new method for estimating current source amplitudes in the brain and heart from external magnetic field measurements and prior knowledge about the probable source positions and amplitudes. The minimum mean square error estimator for the linear inverse problem with statistical prior information was derived and is called the optimal constrained linear inverse method (OCLIM). OCLIM includes as special cases the Shim-Cho weighted pseudoinverse and Wiener estimators but allows more general priors and thus reduces the reconstruction error. Efficient algorithms were developed to compute the OCLIM estimate for instantaneous or time series data. The method was tested in a simulated neuromagnetic imaging problem with five simultaneously active sources on a grid of 387 possible source locations; all five sources were resolved, even though the true sources were not exactly at the modeled source positions and the true source statistics differed from the assumed statistics.
Hughett, P W [Univ. of California, Berkeley, CA (United States). Dept. of Electrical Engineering and Computer Sciences
Characterization of variant forms of organophosphorus hydrolase
that has been shown to detoxify compounds containing P-S bonds, such as VX, a very potent chemical warfare agent . CH~CH20 ~ y y NO2 OCH~CH3 Paraoxon CH3CH~O ? P S ? CHtCH~ S-CH2CH~ OCH~CH3 DemetonS CH3 H ? C ? 0 ? ? F Sarin ~CH CH3CH20 ? P... ? S ? CHtCH2 N OCH2CH3 CH c VX CH Figure 1: Substrates of Organophosphorus Hydrolase There are many practical applications for the OPH enzyme. OPH could be used to detoxify concentrated stockpiles of organophosphorus chemicals. It could also be used...
Rowe, Claire E.
Lipocalin 2 regulation by thermal stresses: Protective role of Lcn2/NGAL against cold and heat stresses
Environmental temperature variations are the most common stresses experienced by a wide range of organisms. Lipocalin 2 (Lcn2/NGAL) is expressed in various normal and pathologic conditions. However, its precise functions have not been fully determined. Here we report the induction of Lcn2 by thermal stresses in vivo, and its role following exposure to cold and heat stresses in vitro. Induction of Lcn2 in liver, heart and kidney was detected by RT-PCR, Western blot and immunohistochemistry following exposure of mice to heat and cold stresses. When CHO and HEK293T cells overexpressing NGAL were exposed to cold stress, cell proliferation was higher compared to controls. Down-regulatrion of NGAL by siRNA in A549 cells resulted in less proliferation when exposed to cold stress compared to control cells. The number of apoptotic cells and expression of pro-apoptotic proteins were lower in the NGAL overexpressing CHO and HEK293T cells, but were higher in the siRNA-transfected A549 cells compared to controls, indicating that NGAL protects cells against cold stress. Following exposure of the cells to heat stress, ectopic expression of NGAL protected cells while addition of exogenous recombinant NGAL to the cell culture medium exacerbated the toxicity of heat stress specially when there was low or no endogenous expression of NGAL. It had a dual effect on apoptosis following heat stress. NGAL also increased the expression of HO-1. Lcn2/NGAL may have the potential to improve cell proliferation and preservation particularly to prevent cold ischemia injury of transplanted organs or for treatment of some cancers by hyperthermia.
Roudkenar, Mehryar Habibi, E-mail: firstname.lastname@example.com [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Halabian, Raheleh [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of)] [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Roushandeh, Amaneh Mohammadi [Department of Anatomy, Faculty of Medicine, Medical University of Tabriz, Tabriz (Iran, Islamic Republic of)] [Department of Anatomy, Faculty of Medicine, Medical University of Tabriz, Tabriz (Iran, Islamic Republic of); Nourani, Mohammad Reza [Chemical Injury Research Center, Baqiyatallah Medical Science University, Tehran (Iran, Islamic Republic of)] [Chemical Injury Research Center, Baqiyatallah Medical Science University, Tehran (Iran, Islamic Republic of); Masroori, Nasser [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of)] [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Ebrahimi, Majid [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of) [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Chemical Injury Research Center, Baqiyatallah Medical Science University, Tehran (Iran, Islamic Republic of); Nikogoftar, Mahin; Rouhbakhsh, Mehdi; Bahmani, Parisa [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of)] [Research Center, Iranian Blood Transfusion Organization, Tehran (Iran, Islamic Republic of); Najafabadi, Ali Jahanian [Department of Molecular Biology, Pasteur Institute of Iran, Tehran (Iran, Islamic Republic of)] [Department of Molecular Biology, Pasteur Institute of Iran, Tehran (Iran, Islamic Republic of); Shokrgozar, Mohammad Ali [National Cell Bank of Iran, Pasteur institute of Iran, Tehran (Iran, Islamic Republic of)] [National Cell Bank of Iran, Pasteur institute of Iran, Tehran (Iran, Islamic Republic of)
Formamide (NH{sub 2}CHO), the simplest possible amide, has recently been suggested to be a central species in the synthesis of metabolic and genetic molecules, the chemical basis of life. In this Letter, we report the first detection of formamide in a protostar, IRAS 16293-2422, which may be similar to the Sun and solar system progenitor. The data combine spectra from the millimeter and submillimeter TIMASSS survey with recent, more sensitive observations at the IRAM 30 m telescope. With an abundance relative to H{sub 2} of {approx}10{sup -10}, formamide appears as abundant in this solar-type protostar as in the two high-mass star-forming regions, Orion-KL and SgrB2, where this species has previously been detected. Given the largely different UV-illuminated environments of the three sources, the relevance of UV photolysis of interstellar ices in the synthesis of formamide is therefore questionable. Assuming that this species is formed in the gas phase via the neutral-neutral reaction between the radical NH{sub 2} and H{sub 2}CO, we predict an abundance in good agreement with the value derived from our observations. The comparison of the relative abundance [NH{sub 2}CHO]/[H{sub 2}O] in IRAS 16293-2422 and in the coma of the comet Hale-Bopp supports the similarity between interstellar and cometary chemistry. Our results thus suggest that the abundance of some cometary organic volatiles could reflect gas phase rather than grain-surface interstellar chemistry.
Kahane, C.; Ceccarelli, C.; Faure, A. [Institut de Planetologie et d'Astrophysique de Grenoble (IPAG) UMR 5274, Universite UJF-Grenoble 1/CNRS-INSU, F-38041 Grenoble (France); Caux, E., E-mail: email@example.com [Universite de Toulouse UPS-OMP, IRAP, F-31028 Toulouse (France)
Final Technical Report "Catalytic Hydrogenation of Carbon Monoxide and Olefin Oxidation" Grant number : DE-FG02-86ER13615
Title: Catalytic Hydrogenation of Carbon Monoxide and Olefin Oxidation Grant No. DE-FG02-86ER13615 PI: Wayland, B. B. (firstname.lastname@example.com) Abstract Development of new mechanistic strategies and catalyst materials for activation of CO, H2, CH4, C2H4, O2, and related substrates relevant to the conversion of carbon monoxide, alkanes, and alkenes to organic oxygenates are central objectives encompassed by this program. Design and synthesis of metal complexes that manifest reactivity patterns associated with potential pathways for the hydrogenation of carbon monoxide through metallo-formyl (M-CHO), dimetal ketone (M-C(O)-M), and dimetal dionyl (M-C(O)-C(O)-M) species is one major focus. Hydrocarbon oxidation using molecular oxygen is a central goal for methane activation and functionalization as well as regioselective oxidation of olefins. Discovery of new reactivity patterns and control of selectivity are pursued through designing new metal complexes and adjusting reaction conditions. Variation of reaction media promotes distinct reaction pathways that control both reaction rates and selectivities. Dimetalloradical diporphyrin complexes preorganize transition states for substrate reactions that involve two metal centers and manifest large rate increases over mono-metalloradical reactions of hydrogen, methane, and other small molecule substrates. Another broad goal and recurring theme of this program is to contribute to the thermodynamic database for a wide scope of organo-metal transformations in a range of reaction media. One of the most complete descriptions of equilibrium thermodynamics for organometallic reactions in water and methanol is emerging from the study of rhodium porphyrin substrate reactions in aqueous and alcoholic media. Water soluble group nine metalloporphyrins manifest remarkably versatile substrate reactivity in aqueous and alcoholic media which includes producing rhodium formyl (Rh-CHO) and hydroxy methyl (Rh-CH2OH) species. Exploratory directions for this program include expending new strategies for anti-Markovnikov addition of water, alcohols, and amines with olefins, developing catalytic reactions of CO to give formamides and formic esters, and evaluating the potential for coupling reactions of CO to produce organic building blocks.
Wayland, B.B.
Histamine acting on H1 receptor promotes inhibition of proliferation via PLC, RAC, and JNK-dependent pathways
It is well established that histamine modulates cell proliferation through the activation of the histamine H1 receptor (H1R), a G protein-coupled receptor (GPCR) that is known to couple to phospholipase C (PLC) activation via Gq. In the present study, we aimed to determine whether H1R activation modulates Rho GTPases, well-known effectors of Gq/G{sub 11}-coupled receptors, and whether such modulation influences cell proliferation. Experiments were carried out in CHO cells stably expressing H1R (CHO-H1R). By using pull-down assays, we found that both histamine and a selective H1R agonist activated Rac and RhoA in a time- and dose-dependent manner without significant changes in the activation of Cdc42. Histamine response was abolished by the H1R antagonist mepyramine, RGS2 and the PLC inhibitor U73122, suggesting that Rac and RhoA activation is mediated by H1R via Gq coupling to PLC stimulation. Histamine caused a marked activation of serum response factor activity via the H1R, as determined with a serum-responsive element (SRE) luciferase reporter, and this response was inhibited by RhoA inactivation with C3 toxin. Histamine also caused a significant activation of JNK which was inhibited by expression of the Rac-GAP {beta}2-chimaerin. On the other hand, H1R-induced ERK1/2 activation was inhibited by U73122 but not affected by C3 or {beta}2-chimaerin, suggesting that ERK1/2 activation was dependent on PLC and independent of RhoA or Rac. [{sup 3}H]-Thymidine incorporation assays showed that both histamine and the H1R agonist inhibited cell proliferation in a dose-dependent manner and that the effect was independent of RhoA but partially dependent on JNK and Rac. Our results reveal that functional coupling of the H1R to Gq-PLC leads to the activation of RhoA and Rac small GTPases and suggest distinct roles for Rho GTPases in the control of cell proliferation by histamine.
Notcovich, Cintia [Laboratorio de Patologia y Farmacologia Molecular, Instituto de Biologia y Medicina Experimental (Argentina) [Laboratorio de Patologia y Farmacologia Molecular, Instituto de Biologia y Medicina Experimental (Argentina); Laboratorio de Farmacologia de Receptores, Catedra de Quimica Medicinal, Departamento de Farmacologia, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires (Argentina); Diez, Federico [Laboratorio de Farmacologia de Receptores, Catedra de Quimica Medicinal, Departamento de Farmacologia, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires (Argentina)] [Laboratorio de Farmacologia de Receptores, Catedra de Quimica Medicinal, Departamento de Farmacologia, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires (Argentina); Tubio, Maria Rosario [Laboratorio de Patologia y Farmacologia Molecular, Instituto de Biologia y Medicina Experimental (Argentina) [Laboratorio de Patologia y Farmacologia Molecular, Instituto de Biologia y Medicina Experimental (Argentina); Laboratorio de Farmacologia de Receptores, Catedra de Quimica Medicinal, Departamento de Farmacologia, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires (Argentina); Baldi, Alberto [Laboratorio de Patologia y Farmacologia Molecular, Instituto de Biologia y Medicina Experimental (Argentina) [Laboratorio de Patologia y Farmacologia Molecular, Instituto de Biologia y Medicina Experimental (Argentina); Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires (Argentina); Kazanietz, Marcelo G. [Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 (United States)] [Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 (United States); Davio, Carlos [Laboratorio de Farmacologia de Receptores, Catedra de Quimica Medicinal, Departamento de Farmacologia, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires (Argentina) [Laboratorio de Farmacologia de Receptores, Catedra de Quimica Medicinal, Departamento de Farmacologia, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires (Argentina); Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires (Argentina); Shayo, Carina, E-mail: email@example.com [Laboratorio de Patologia y Farmacologia Molecular, Instituto de Biologia y Medicina Experimental (Argentina) [Laboratorio de Patologia y Farmacologia Molecular, Instituto de Biologia y Medicina Experimental (Argentina); Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires (Argentina)
Higher coronary heart disease and heart attack morbidity in Appalachian coal mining regions
This study analyzes the U.S. 2006 Behavioral Risk Factor Surveillance System survey data (N = 235,783) to test whether self-reported cardiovascular disease rates are higher in Appalachian coal mining counties compared to other counties after control for other risks. Dependent variables include self-reported measures of ever (1) being diagnosed with cardiovascular disease (CVD) or with a specific form of CVD including (2) stroke, (3) heart attack, or (4) angina or coronary heart disease (CHD). Independent variables included coal mining, smoking, BMI, drinking, physician supply, diabetes co-morbidity, age, race/ethnicity, education, income, and others. SUDAAN Multilog models were estimated, and odds ratios tested for coal mining effects. After control for covariates, people in Appalachian coal mining areas reported significantly higher risk of CVD (OR = 1.22, 95% CI = 1.14-1.30), angina or CHO (OR = 1.29, 95% C1 = 1.19-1.39) and heart attack (OR = 1.19, 95% C1 = 1.10-1.30). Effects were present for both men and women. Cardiovascular diseases have been linked to both air and water contamination in ways consistent with toxicants found in coal and coal processing. Future research is indicated to assess air and water quality in coal mining communities in Appalachia, with corresponding environmental programs and standards established as indicated.
Hendryx, M.; Zullig, K.J. [West Virginia University, Morgantown, WV (United States). Dept. of Community Medicine
Complex organic molecules in organic-poor massive young stellar objects
Massive young stellar objects (MYSOs) with hot cores are classic sources of complex organic molecules. The origins of these molecules in such sources, as well as the small- and large-scale differentiation between nitrogen- and oxygen-bearing complex species, are poorly understood. We aim to use complex molecule abundances toward a chemically less explored class of MYSOs with weak hot organic emission lines to constrain the impact of hot molecular cores and initial ice conditions on the chemical composition toward MYSOs. We use the IRAM 30m and the Submillimeter Array to search for complex organic molecules over 8-16 GHz in the 1~mm atmospheric window toward three MYSOs with known ice abundances, but without luminous molecular hot cores. Complex molecules are detected toward all three sources at comparable abundances with respect to CH$_3$OH to classical hot core sources. The relative importance of CH$_3$CHO, CH$_3$CCH, CH$_3$OCH$_3$, CH$_3$CN, and HNCO differ between the organic-poor MYSOs and hot cores, howe...
Fayolle, Edith C; Garrod, Robin T; van Dishoeck, Ewine F; Bisschop, Suzanne E
Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts
It has been suggested that cholesterol may modulate amyloid-{beta} (A{beta}) formation, a causative factor of Alzheimer's disease (AD), by regulating distribution of the three key proteins in the pathogenesis of AD ({beta}-amyloid precursor protein (APP), {beta}-secretase (BACE1) and/or presenilin 1 (PS1)) within lipid rafts. In this work we tested whether cholesterol accumulation upon NPC1 dysfunction, which causes Niemann Pick type C disease (NPC), causes increased partitioning of APP into lipid rafts leading to increased CTF/A{beta} formation in these cholesterol-rich membrane microdomains. To test this we used CHO NPC1{sup -/-} cells (NPC cells) and parental CHOwt cells. By sucrose density gradient centrifugation we observed a shift in fl-APP/CTF compartmentalization into lipid raft fractions upon cholesterol accumulation in NPC vs. wt cells. Furthermore, {gamma}-secretase inhibitor treatment significantly increased fl-APP/CTF distribution in raft fractions in NPC vs. wt cells, suggesting that upon cholesterol accumulation in NPC1-null cells increased formation of APP-CTF and its increased processing towards A{beta} occurs in lipid rafts. Our results support that cholesterol overload, such as in NPC disease, leads to increased partitioning of APP/CTF into lipid rafts resulting in increased amyloidogenic processing of APP in these cholesterol-rich membranes. This work adds to the mechanism of the cholesterol-effect on APP processing and the pathogenesis of Alzheimer's disease and supports the role of lipid rafts in these processes.
Kosicek, Marko, E-mail: email@example.com [Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka 54, 10000 Zagreb (Croatia)] [Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka 54, 10000 Zagreb (Croatia); Malnar, Martina, E-mail: email@example.com [Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka 54, 10000 Zagreb (Croatia)] [Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka 54, 10000 Zagreb (Croatia); Goate, Alison, E-mail: firstname.lastname@example.com [Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110 (United States)] [Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110 (United States); Hecimovic, Silva, E-mail: email@example.com [Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka 54, 10000 Zagreb (Croatia)] [Division of Molecular Medicine, Ruder Boskovic Institute, Bijenicka 54, 10000 Zagreb (Croatia)
Complex organic molecules in protostellar environments in the SKA era
Molecular complexity builds up at each step of the Sun-like star formation process, starting from simple molecules and ending up in large polyatomic species. Complex organic molecules (COMs; such as methyl formate, HCOOCH$_3$, dymethyl ether, CH$_3$OCH$_3$, formamide, NH$_2$CHO, or glycoaldehyde, HCOCH$_2$OH) are formed in all the components of the star formation recipe (e.g. pre-stellar cores, hot-corinos, circumstellar disks, shocks induced by fast jets), due to ice grain mantle sublimation or sputtering as well as gas-phase reactions. Understanding in great detail the involved processes is likely the only way to predict the ultimate molecular complexity reached in the ISM, as the detection of large molecules is increasingly more difficult with the increase of the number of atoms constituting them. Thanks to the recent spectacular progress of astronomical observations, due to the Herschel (sub-mm and IR), IRAM and SMA (mm and sub-mm), and NRAO (cm) telescopes, an enormous activity is being developed in the ...
Codella, C; Fontani, F; JimÕnez-Serra, I; Caselli, P; Ceccarelli, C; Palumbo, M E; Lµpez-Sepulcre, A; BeltrÃn, M T; Lefloch, B; Brucato, J R; Viti, S; Testi, L
Crosslinked Polyamide
A crosslinked polyamide material and a process for preparing the crosslinked polyamide material are disclosed. The crosslinked polyamide material comprises a crosslinked chemical combination of (1) a polyamide of the formula: ##STR1## wherein n is between about 50 and 10,000, wherein each R is between 1 and 50 carbon atoms alone and is optionally substituted with heteroatoms, oxygen, nitrogen, sulfur, or phosphorus and combinations thereof, wherein multiple of the R are in vertically aligned spaced relationship along a backbone forming the polyamide, and wherein two or more of the R contain an amino group; and (2) a crosslinking agent containing at least two functional groups capable of reacting with the amino groups of the polyamide. In one embodiment of the invention, the crosslinking agent is an aliphatic or aromatic isocyanate compound having 2 or more --N.dbd.C.dbd.O groups. In another embodiment of the invention, the crosslinking agent is an aliphatic aldehyde or aromatic aldehyde compound having 2 or more --CHO groups. In still another embodiment of the invention, the crosslinking agent is selected from a phosphine having the general formula (A).sub.2 P(B) and mixtures thereof, wherein A is hydroxyalkyl, and B is hydroxyalkyl, alkyl, or aryl. In yet another embodiment of the invention, the crosslinking agent is selected from the group consisting of epoxy resins having more than one epoxide group per molecule.
Huang, Zhi H. (East Lansing, MI); McDonald, William F. (Utica, OH); Wright, Stacy C. (Lansing, MI); Taylor, Andrew C. (Ann Arbor, MI)
GAS-PHASE REACTIONS OF HYDRIDE ANION, H{sup -}
Rate constants were measured at 300 K for the reactions of the hydride anion, H{sup -}, with neutral molecules C{sub 2}H{sub 2}, H{sub 2}O, CH{sub 3}CN, CH{sub 3}OH, (CH{sub 3}){sub 2}CO, CH{sub 3}CHO, N{sub 2}O, CO{sub 2}, O{sub 2}, CO, CH{sub 3}Cl, (CH{sub 3}){sub 3}CCl, (CH{sub 3}CH{sub 2}){sub 2}O, C{sub 6}H{sub 6}, and D{sub 2} using a flowing-afterglow instrument. Experimental work was supplemented by ab initio calculations to provide insight into the viability of reaction pathways. Our reported rate constants should prove useful to models of astrophysical environments where conditions prevail for the existence of both H{sup -} and neutral species. The variety of neutral reactants studied includes representative species from prototypical chemical groups, effectively mapping reactivity trends for the hydride anion.
Martinez, Oscar; Yang Zhibo; Demarais, Nicholas J.; Bierbaum, Veronica M. [Department of Chemistry and Biochemistry, 215 UCB, University of Colorado, Boulder, CO 80309-0215 (United States); Snow, Theodore P., E-mail: email@example.com, E-mail: email@example.com, E-mail: email@example.com, E-mail: firstname.lastname@example.com, E-mail: email@example.com [Department of Astrophysical and Planetary Sciences, 391 UCB, University of Colorado, Boulder, CO 80309-0391 (United States)
We have studied reactions of small dehydrogenated polycyclic aromatic hydrocarbon anions with neutral species of interstellar relevance. Reaction rate constants are measured at 300 K for the reactions of phenide (C{sub 6}H{sup -}{sub 5}), naphthalenide (C{sub 10}H{sup -}{sub 7}), and anthracenide (C{sub 14}H{sup -}{sub 9}) with atomic H, H{sub 2}, and D{sub 2} using a flowing afterglow-selected ion flow tube instrument. Reaction rate constants of phenide with neutral molecules (CO, O{sub 2}, CO{sub 2}, N{sub 2}O, C{sub 2}H{sub 2}, CH{sub 3}OH, CH{sub 3}CN, (CH{sub 3}){sub 2}CO, CH{sub 3}CHO, CH{sub 3}Cl, and (CH{sub 3}CH{sub 2}){sub 2}O) are also measured under the same conditions. Experimental measurements are accompanied by ab initio calculations to provide insight into reaction pathways and enthalpies. Our measured reaction rate constants should prove useful in the modeling of astrophysical environments, particularly when applied to dense regions of the interstellar and circumstellar medium.
Demarais, Nicholas J.; Yang Zhibo; Martinez, Oscar; Wehres, Nadine; Bierbaum, Veronica M. [Department of Chemistry and Biochemistry, 215 UCB, University of Colorado, Boulder, CO 80309-0215 (United States); Snow, Theodore P., E-mail: email@example.com, E-mail: email@example.com, E-mail: firstname.lastname@example.com, E-mail: email@example.com, E-mail: email@example.com, E-mail: email@example.com [Center for Astrophysics and Space Astronomy, 389 UCB, University of Colorado, Boulder, CO 80309-0389 (United States)
The Static Quark Potential from the Gauge Independent Abelian Decomposition
We investigate the relationship between colour confinement and the gauge independent Cho-Duan-Ge Abelian decomposition. The decomposition is defined in terms of a colour field $n$; the principle novelty of our study is that we have defined this field in terms of the eigenvectors of the Wilson Loop. This establishes an equivalence between the path ordered integral of the non-Abelian gauge fields with an integral over an Abelian restricted gauge field which is tractable both theoretically and numerically in lattice QCD. We circumvent path ordering without needing an additional path integral. By using Stokes' theorem, we can compute the Wilson Loop in terms of a surface integral over a restricted field strength, and show that the restricted field strength may be dominated by certain structures, which occur when one of the quantities parametrising the colour field $n$ winds itself around a non-analyticity in the colour field. If they exist, these structures will lead to a area law scaling for the Wilson Loop and ...
Cundy, Nigel; Lee, Weonjong
Modeling of the formation of short-chain acids in propane flames
In order to better understand their potential formation in combustion systems, a detailed kinetic mechanism for the formation of short-chain monocarboxylic acids, formic (HCOOH), acetic (CH3COOH), propionic (C2H5COOH) and propenic (C2H3COOH)) acids, has been developed. Simulations of lean (equivalence ratios from 0.9 to 0.48) laminar premixed flames of propane stabilized at atmospheric pressure with nitrogen as diluent have been performed. It was found that amounts up to 25 ppm of acetic acid, 15 ppm of formic acid and 1 ppm of C3 acid can be formed for some positions in the flames. Simulations showed that the more abundant C3 acid formed is propenic acid. A quite acceptable agreement has been obtained with the scarce results from the literature concerning oxygenated compounds, including aldehydes (CH2O, CH3CHO) and acids. A reaction pathways analysis demonstrated that each acid is mainly derived from the aldehyde of similar structure.
Battin-Leclerc, FrÕdÕrique; Jaffrezo, J L; Legrand, M
DOE Chair of Excellence in Environmental Disciplines-Final Technical Report
The report Massie Chair of Excellence Program at Universidad del Turabo, contract DE-FG02-95EW12610, during the period of 9/29/1995 to 9/29/2011. The initial program aims included development of academic programs in the Environmental Sciences and Engineering, and Research and Development focused initially on environmentally friendly processes and later revised also include: renewable energy and international cooperation. From 1995 -2005, the Program at UT lead the establishment of the new undergraduate program in electrical engineering at the School of Engineering (SoE), worked on requirements to achieve ABET accreditation of the SoE B.S. Mechanical Engineering and B.S. Electrical Engineering programs, mentored junior faculty, taught undergraduate courses in electrical engineering, and revised the electrical engineering curriculum. Engineering undergraduate laboratories were designed and developed. The following research sub-project was developed: Research and development of new perovskite-alumina hydrogen permeable asymmetrical nanostructured membranes for hydrogen purification, and extremely high specific surface area silica materials for hydrogen storage in the form of ammonia, Dr. Rolando Roque-Malherbe Subproject PI, Dr. Santander Nieto and Mr. Will Gµmez Research Assistants. In 2006, the Massie Chair of Excellence Program was transferred to the National Nuclear Security Agency, NNSA and DNN. DoE required a revised proposal aligned with the priorities of the Administration. The revised approved program aims included: (1) Research (2) Student Development: promote the development of minority undergraduate and graduate students through research teams, internships, conferences, new courses; and, (3) Support: (a) Research administration and (b) Dissemination through international conferences, the UT Distinguished Lecturer Series in STEM fields and at the annual Universidad del Turabo (UT) Researchers Conference. Research included: Sub-Project 1: Synthesis and Characterization of low Refractive Index Aerogel Silica for Cherenkov Counters- Dr. Rolando Roque-Malherbe Sub-project PI, Dr. Jose Duconge Sub-project Co-PI, Dr. Santander Nieto Assistant Researcher, Francisco Diaz and Carlos Neira Associate Researchers. The initial aim of this sub-project was changed to the synthesis and characterization of extremely high specific surface area aerogel silica for gas storage. A high specific surface area silica gel that has applications in gas drying, cleaning operation useful in nuclear industry in process was developed. Sub-Project 2: Investigation Study of Magnetic and Electronic Transport Properties at Material Interfaces in Magnetic Multilayer Heterostructure using Gd. Dr. Yazan Hijazi, Sub-project Co-PI. UT developed the capability and infrastructure to produce high quality thin-film magnetic films and magnetic multilayer structures with fine control over film quality and thickness using sputter deposition capability to perform in-house electric and magnetic characterization of these films. The research experimentally quantified the effect of Gd incorporation within the magnetic multilayer structure and produce magnetic media with exchanged decoupled multilevel magnetic anisotropy. From September 2006 to September 2011 the Massie Chair produced nineteen (19) publications, (including 3 books), five (5) presentations and three (3) international conferences abstracts. A total of fourteen (14) undergraduates and (6) graduate students acquired research experience. Two Ph.D. students presented their dissertations on topics related to nuclear energy and graduated as follows: MarÚa Cotto (May 2009) and Eric Calderµn (May 2011). Five of the participating undergraduate students graduated: Ramon Polanco (BSME, May 2009), Jason PÕrez (BSEE, May 2008), Rafael Colµn (BSME, May 2008), Jessenia Marfisi (BS Chemistry, May 2008). Eleven (11) students were sent to National Laboratories (LANL, SNL and LLNL), NNSA and DoE facilities for summer internships. Twenty eight (28) undergraduate students participated in Summer Internships (2010,
Kurunganty, Sastry; LorÃn, Roberto; Roque-Malherbe, Rolando; Hijazi, Yazan; Nieto, Santander; Gµmez, Will A.; DucongÕ, JosÕ; Cotto, MarÚa del C.; Muþiz, Carlos; DÚaz, Francisco J.; Neira, Carlos F.; MÃrquez, Francisco; Del Valle, W.; Thommes, M.
Guest Editorial: Laser Damage
Laser damage of optical materials, first reported in 1964, continues to limit the output energy and power of pulsed and continuous-wave laser systems. In spite of some 48 years of research in this area, interest from the international laser community to laser damage issues remains at a very high level and does not show any sign of decreasing. Moreover, it grows with the development of novel laser systems, for example, ultrafast and short-wavelength lasers that involve new damage effects and specific mechanisms not studied before. This interest is evident from the high level of attendance and presentations at the annual SPIE Laser Damage Symposium (aka, Boulder Damage Symposium) that has been held in Boulder, Colorado, since 1969. This special section of Optical Engineering is the first one devoted to the entire field of laser damage rather than to a specific part. It is prepared in response to growing interest from the international laser-damage community. Some papers in this special section were presented at the Laser Damage Symposium; others were submitted in response to the general call for papers for this special section. The 18 papers compiled into this special section represent many sides of the broad field of laser-damage research. They consider theoretical studies of the fundamental mechanisms of laser damage including laser-driven electron dynamics in solids (O. Brenk and B. Rethfeld; A. Nikiforov, A. Epifanov, and S. Garnov; T. Apostolova et al.), modeling of propagation effects for ultrashort high-intensity laser pulses (J. Gulley), an overview of mechanisms of inclusion-induced damage (M. Koldunov and A. Manenkov), the formation of specific periodic ripples on a metal surface by femtosecond laser pulses (M. Ahsan and M. Lee), and the laser-plasma effects on damage in glass (Y. Li et al). Material characterization is represented by the papers devoted to accurate and reliable measurements of absorption with special emphasis on thin films (C. M■hlig and S. Bublitz; B. Cho, E. Danielewicz, and J. Rudisill; W. Palm et al; and J. Lu et al.). Statistical treatment of measurements of the laser-damage threshold (J. Arenberg) and the relationship to damage mechanisms (F. Wagner et al.) represent the large subfield of laser-damage measurements. Various aspects of multilayer coating and thin-film characterization are considered in papers by B. Cho, J. Rudisill, and E. Danielewicz (spectral shift in multilayer mirrors) and R. Weber et al. (novel approach to damage studies based on third-harmonic generation microscopy). Of special interest for readers is the paper by C. Stolz that summarizes the results of four thin-film damage competitions organized as a part of the Laser Damage Symposium. Another paper is devoted to thermal annealing of damage precursors (N. Shen et al.). Finally, the influence of nano-size contamination on initiation of laser damage by ultrashort pulses is considered in paper of V. Komolov et al.
Vitaly Gruzdev, Michelle D. Shinn
An Exocyclic Methylene Group Acts As a Bioisostere of the 2?-Oxygen Atom in LNA
We show for the first time that it is possible to obtain LNA-like (Locked Nucleic Acid 1) binding affinity and biological activity with carbocyclic LNA (cLNA) analogs by replacing the 2{prime}-oxygen atom in LNA with an exocyclic methylene group. Synthesis of the methylene-cLNA nucleoside was accomplished by an intramolecular cyclization reaction between a radical at the 2{prime}-position and a propynyl group at the C-4{prime} position. Only methylene-cLNA modified oligonucleotides showed similar thermal stability and mismatch discrimination properties for complementary nucleic acids as LNA. In contrast, the close structurally related methyl-cLNA analogs showed diminished hybridization properties. Analysis of crystal structures of cLNA modified self-complementary DNA decamer duplexes revealed that the methylene group participates in a tight interaction with a 2{prime}-deoxyribose residue of the 5{prime}-terminal G of a neighboring duplex, resulting in the formation of a CH...O type hydrogen bond. This indicates that the methylene group retains a negative polarization at the edge of the minor groove in the absence of a hydrophilic 2{prime}-substituent and provides a rationale for the superior thermal stability of this modification. In animal experiments, methylene-cLNA antisense oligonucleotides (ASOs) showed similar in vivo activity but reduced toxicity as compared to LNA ASOs. Our work highlights the interchangeable role of oxygen and unsaturated moieties in nucleic acid structure and emphasizes greater use of this bioisostere to improve the properties of nucleic acids for therapeutic and diagnostic applications.
Seth, Punit P.; Allerson, Charles R.; Berdeja, Andres; Siwkowski, Andrew; Pallan, Pradeep S.; Gaus, Hans; Prakash, Thazha P.; Watt, Andrew T.; Egli, Martin; Swayze, Eric E. (Isis Pharm.); (Vanderbilt)
ELECTRON IRRADIATION OF KUIPER BELT SURFACE ICES: TERNARY N{sub 2}-CH{sub 4}-CO MIXTURES AS A CASE STUDY
The space weathering of icy Kuiper Belt Objects was investigated in this case study by exposing methane (CH{sub 4}) and carbon monoxide (CO) doped nitrogen (N{sub 2}) ices at 10 K to ionizing radiation in the form of energetic electrons. Online and in situ Fourier transform infrared spectroscopy was utilized to monitor the radiation-induced chemical processing of these ices. Along with isocyanic acid (HNCO), the products could be mainly derived from those formed in irradiated binary ices of the N{sub 2}-CH{sub 4} and CO-CH{sub 4} systems: nitrogen-bearing products were found in the form of hydrogen cyanide (HCN), hydrogen isocyanide (HNC), diazomethane (CH{sub 2}N{sub 2}), and its radical fragment (HCN{sub 2}); oxygen-bearing products were of acetaldehyde (CH{sub 3}CHO), formyl radical (HCO), and formaldehyde (H{sub 2}CO). As in the pure ices, the methyl radical (CH{sub 3}) and ethane (C{sub 2}H{sub 6}) were also detected, as were carbon dioxide (CO{sub 2}) and the azide radical (N{sub 3}). Based on the temporal evolution of the newly formed products, kinetic reaction schemes were then developed to fit the temporal profiles of the newly formed species, resulting in numerical sets of rate constants. The current study highlights important constraints on the preferential formation of isocyanic acid (HNCO) over hydrogen cyanide (HCN) and hydrogen isocyanide (HNC), thus guiding the astrobiological and chemical evolution of those distant bodies.
Kim, Y. S.; Kaiser, R. I., E-mail: firstname.lastname@example.com [Department of Chemistry, University of Hawaii at Manoa, Honolulu, HI 96822 (United States)
Currently used pesticides and their mixtures affect the function of sex hormone receptors and aromatase enzyme activity
The endocrine-disrupting potential of pesticides is of health concern, since they are found ubiquitously in the environment and in food items. We investigated in vitro effects on estrogen receptor (ER) and androgen receptor (AR) transactivity, and aromatase enzyme activity, of the following pesticides: 2-methyl-4-chlorophenoxyacetic acid (MCPA), terbuthylazine, iodosulfuron-methyl-sodium, mesosulfuron-methyl, metsulfuron-methyl, chlormequat chloride, bitertanol, propiconazole, prothioconazole, mancozeb, cypermethrin, tau fluvalinate, malathion and the metabolite ethylene thiourea (ETU). The pesticides were analyzed alone and in selected mixtures. Effects of the pesticides on ER and AR function were assessed in human breast carcinoma MVLN cells and hamster ovary CHO-K1 cells, respectively, using luciferase reporter gene assays. Effects on aromatase enzyme activity were analyzed in human choriocarcinoma JEG-3 cells, employing the classical [{sup 3}H]{sub 2}O method. Five pesticides (terbuthylazine, propiconazole, prothioconazole, cypermethrin and malathion) weakly induced the ER transactivity, and three pesticides (bitertanol, propiconazole and mancozeb) antagonized the AR activity in a concentration-dependent manner. Three pesticides (terbuthylazine, propiconazole and prothioconazole) weakly induced the aromatase activity. In addition, two mixtures, consisting of three pesticides (bitertanol, propiconazole, cypermethrin) and five pesticides (terbuthylazine, bitertanol, propiconazole, cypermethrin, malathion), respectively, induced the ER transactivity and aromatase activity, and additively antagonized the AR transactivity. In conclusion, our data suggest that currently used pesticides possess endocrine-disrupting potential in vitro which can be mediated via ER, AR and aromatase activities. The observed mixture effects emphasize the importance of considering the combined action of pesticides in order to assure proper estimations of related health effect risks. - Highlights: Currently used pesticides possess endocrine-disrupting (ED) potential in vitro. ED effects can be mediated via sex hormone receptors and/or the aromatase enzyme. Additive mixture effects on androgen receptor transactivity were observed.
Kjeldsen, Lisbeth Stigaard; Ghisari, Mandana; Bonefeld-J½rgensen, Eva Cecilie, E-mail: firstname.lastname@example.com
Dual effects of N-acetyl-L-cysteine dependent on NQO1 activity: Suppressive or promotive of 9,10-phenanthrenequinone-induced toxicity
A typical antioxidant, N-acetyl-L-cysteine (NAC) generally protects cells from oxidative damage induced by reactive oxygen species (ROS). 9,10-Phenanthrenequinone (9,10-PQ), a major quinone in diesel exhaust particles, produces ROS in redox cycling following two-electron reduction by NAD(P)H:quinone oxidoreductase 1 (NQO1), which has been considered as a cause of its cyto- and genotoxicity. In this study, we show that NAC unexpectedly augments the toxicity of 9,10-PQ in cells with low NQO1 activity. In four human skin cell lines, the expression and the activity of NQO1 were lower than in human adenocarcinoma cell lines, A549 and MCF7. In the skin cells, the cytotoxicity of 9,10-PQ was significantly enhanced by addition of NAC. The formation of DNA double strand breaks accompanying phosphorylation of histone H2AX, was also remarkably augmented. On the other hand, the cyto- and genotoxicity were suppressed by addition of NAC in the adenocarcinoma cells. Two contrasting experiments: overexpression of NQO1 in CHO-K1 cells which originally expressed low NQO1 levels, and knock?down of NQO1 in the adenocarcinoma cell line A549 by transfection of RNAi, also showed that NAC suppressed 9,10-PQ-induced toxicity in cell lines expressing high NQO1 activity and enhanced it in cell lines with low NQO1 activity. The results suggested that dual effects of NAC on the cyto- and genotoxicity of 9,10-PQ were dependent on tissue-specific NQO1 activity. -- Highlights: ? NAC augmented the cytotoxicity of 9,10-PQ in skin cell lines. ? 9,10-PQ-induced DSBs accompanying ?-H2AX were also augmented by NAC. ? NAC suppressed the cyto- and genotoxicity of 9,10-PQ in adenocarcinoma cell lines. ? The dual effects of NAC on toxicity of 9,10-PQ were dependent on NQO1 activity.
Toyooka, Tatsushi; Shinmen, Takuya [Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka (Japan)] [Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka (Japan); Aarts, Jac M.M.J.G. [Division of Toxicology, Wageningen University, Wageningen (Netherlands); Ibuki, Yuko, E-mail: email@example.com [Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka (Japan)] [Graduate School of Nutritional and Environmental Sciences, University of Shizuoka, Shizuoka (Japan)
Conversion of 1,3-Propylene Glycol on Rutile TiO2(110)
The adsorption of 1,3-propylene glycol (1,3-PG) on partially reduced TiO2(110) and its conversion to products have been studied by a combination of molecular beam dosing and temperature programmed desorption (TPD). When the Ti surface sites are saturated by 1,3-PG, ~80% of the molecules undergo further reactions to yield products that are liberated during the TPD ramp. In contrast to ethylene glycol (EG) and 1,2- propylene glycol (1,2-PG) that yield only alkenes and water at very low coverages (< 0.05 ML), two additional products, HCHO and C2H4, along with propylene (CH3CHCH2) and water are observed for 1,3-PG. Identical TPD line shapes and desorption yields for HCHO and C2H4 suggest that these products result from C-C bond cleavage and are coupled. At higher 1,3-PG coverages (> 0.1 ML), propanal (CH3CH2CHO) and two additional products, 1-propanol (CH3CH2CH2OH) and acrolein (CH2CHCHO), are observed. The desorption of 1-propanol is found to be coupled with the desorption of acrolein, suggesting that these products are formed by the disproportionation of two 1,3-PG molecules. The coverage dependent TPD results further show that propylene formation dominates at low coverages (< 0.3 ML), while the decomposition and disproportionation channels increase rapidly at higher coverages and reach yields comparable to that of propylene at the 1,3-PG saturation coverage of 0.5 ML. The observed surface chemistry clearly shows how the molecular structure of glycols influences their reaction pathways on oxide surfaces.
Chen, Long; Li, Zhenjun; Smith, R. Scott; Kay, Bruce D.; Dohnalek, Zdenek
INTERMEDIATE-MASS HOT CORES AT {approx}500 AU: DISKS OR OUTFLOWS?
Observations with the Plateau de Bure Interferometer in the most extended configuration toward two intermediate-mass star-forming regions, IRAS 22198+6336 and AFGL 5142, reveal the presence of several complex organic molecules at {approx}500 AU scales, confirming the presence of hot cores in both regions. The hot cores are not rich in CN-bearing molecules, as often seen in massive hot cores, and are mainly traced by CH{sub 3}CH{sub 2}OH, (CH{sub 2}OH){sub 2}, CH{sub 3}COCH{sub 3}, and CH{sub 3}OH, with, additionally, CH{sub 3}CHO, CH{sub 3}OD, and HCOOD for IRAS 22198+6336, and C{sub 6}H and O{sup 13}CS for AFGL 5142. The emission of complex molecules is resolved down to sizes of {approx}300 and {approx}600 AU, for IRAS 22198+6336 and AFGL 5142, respectively, and most likely is tracing protostellar disks rather than flattened envelopes or toroids as is usually found. This is especially clear for the case of IRAS 22198+6336, where we detect a velocity gradient for all the mapped molecules perpendicular to the most chemically rich outflow of the region, yielding a dynamic mass {approx}> 4 M{sub Sun }. As for AFGL 5142, the hot core emission is resolved into two elongated cores separated {approx}1800 AU. A detailed comparison of the complex molecule peaks to the new CO (2-1) data and H{sub 2}O maser data from the literature suggests also that for AFGL 5142 the complex molecules are mainly associated with disks, except for a faint and extended molecular emission found to the west, which is possibly produced in the interface between one of the outflows and the dense surrounding gas.
Palau, Aina; Girart, Josep M. [Institut de Ciencies de l'Espai (CSIC-IEEC), Campus UAB-Facultat de Ciencies, Torre C5-parell 2, 08193 Bellaterra, Catalunya (Spain); Fuente, Asuncion; Alonso-Albi, Tomas [Observatorio Astronomico Nacional, P.O. Box 112, 28803 Alcala de Henares, Madrid (Spain); Fontani, Francesco; Sanchez-Monge, Alvaro [Osservatorio Astrofisico di Arcetri, INAF, Largo E. Fermi 5, 50125 Firenze (Italy); Boissier, Jeremie [Istituto di Radioastronomia, INAF, Via Gobetti 101, Bologna (Italy); Pietu, Vincent; Neri, Roberto [IRAM, 300 Rue de la piscine, 38406 Saint Martin d'Heres (France); Busquet, Gemma [Istituto di Fisica dello Spazio Interplanetario, INAF, Area di Recerca di Tor Vergata, Via Fosso Cavaliere 100, 00133 Roma (Italy); Estalella, Robert [Departament d'Astronomia i Meteorologia (IEEC-UB), Institut Ciencies Cosmos, Universitat Barcelona, Marti Franques 1, 08028 Barcelona (Spain); Zapata, Luis A. [Centro de Radioastronomia y Astrofisica, Universidad Nacional Autonoma de Mexico, P.O. Box 3-72, 58090 Morelia, Michoacan (Mexico); Zhang, Qizhou; Ho, Paul T. P. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Audard, Marc, E-mail: email@example.com [Geneva Observatory, University of Geneva, Ch. des Maillettes 51, 1290 Versoix (Switzerland)
Low doses of alpha particles do not induce sister chromatid exchanges in bystander Chinese hamster cells defective in homologous recombination
We reported previously that the homologous recombinational repair (HRR)-deficient Chinese hamster mutant cell line irs3 (deficient in the Rad51 paralog Rad51C) showed only a 50% spontaneous frequency of sister chromatid exchange (SCE) as compared to parental wild-type V79 cells. Furthermore, when irradiated with very low doses of alpha particles, SCEs were not induced in irs3 cells, as compared to a prominent bystander effect observed in V79 cells (Nagasawa et al., Radiat. Res. 164, 141-147, 2005). In the present study, we examined additional Chinese hamster cell lines deficient in the Rad51 paralogs Rad51C, Rad51D, Xrcc2, and Xrcc3 as well as another essential HRR protein, Brca2. Spontaneous SCE frequencies in non-irradiated wild-type cell lines CHO, AA8 and V79 were 0.33 SCE/chromosome, whereas two Rad51C-deficient cell lines showed only 0.16 SCE/chromosome. Spontaneous SCE frequencies in cell lines defective in Rad51D, Xrcc2, Xrcc3, and Brca2 ranged from 0.23-0.33 SCE/chromosome, 0-30% lower than wild-type cells. SCEs were induced significantly 20-50% above spontaneous levels in wild-type cells exposed to a mean dose of 1.3 mGy of alpha particles (<1% of nuclei traversed by an alpha particle). However, induction of SCEs above spontaneous levels was minimal or absent after {alpha}-particle irradiation in all of the HRR-deficient cell lines. These data suggest that Brca2 and the Rad51 paralogs contribute to DNA damage repair processes induced in bystander cells (presumably oxidative damage repair in S-phase cells) following irradiation with very low doses of alpha particles.
Nagasawa, H; Wilson, P F; Chen, D J; Thompson, L H; Bedford, J S; Little, J B
Uptake and cytotoxic effects of multi-walled carbon nanotubes in human bronchial epithelial cells
Carbon nanotubes (CNT) are cytotoxic to several cell types. However, the mechanism of CNT toxicity has not been fully studied, and dosimetric analyses of CNT in the cell culture system are lacking. Here, we describe a novel, high throughput method to measure cellular uptake of CNT using turbimetry. BEAS-2B, a human bronchial epithelial cell line, was used to investigate cellular uptake, cytotoxicity, and inflammatory effects of multi-walled CNT (MWCNT). The cytotoxicity of MWCNT was higher than that of crocidolite asbestos in BEAS-2B cells. The IC{sub 50} of MWCNT was 12 {mu}g/ml, whereas that of asbestos (crocidolite) was 678 {mu}g/ml. Over the course of 5 to 8 h, BEAS-2B cells took up 17-18% of the MWCNT when they were added to the culture medium at a concentration of 10 {mu}g/ml. BEAS-2B cells were exposed to 2, 5, or 10 {mu}g/ml of MWCNT, and total RNA was extracted for cytokine cDNA primer array assays. The culture supernatant was collected for cytokine antibody array assays. Cytokines IL-6 and IL-8 increased in a dose dependent manner at both the mRNA and protein levels. Migration inhibitory factor (MIF) also increased in the culture supernatant in response to MWCNT. A phosphokinase array study using lysates from BEAS-2B cells exposed to MWCNT indicated that phosphorylation of p38, ERK1, and HSP27 increased significantly in response to MWCNT. Results from a reporter gene assays using the NF-{kappa}B or AP-1 promoter linked to the luciferase gene in transiently transfected CHO-KI cells revealed that NF-{kappa}B was activated following MWCNT exposure, while AP-1 was not changed. Collectively, MWCNT activated NF-{kappa}B, enhanced phosphorylation of MAP kinase pathway components, and increased production of proinflammatory cytokines in human bronchial epithelial cells.
Hirano, Seishiro, E-mail: firstname.lastname@example.com [Environmental Nanotoxicology Section, RCER, National Institute for Environmental Studies (Japan); Fujitani, Yuji; Furuyama, Akiko [Environmental Nanotoxicology Section, RCER, National Institute for Environmental Studies (Japan); Kanno, Sanae [Photon Medical Research Center, Hamamatsu University School of Medicine (Japan)
We investigate the relationship between colour confinement and the gauge independent Cho-Duan-Ge Abelian decomposition. The decomposition is defined in terms of a colour field $n$; the principle novelty of our study is that we have defined this field in terms of the eigenvectors of the Wilson Loop. This establishes an equivalence between the path ordered integral of the non-Abelian gauge fields with an integral over an Abelian restricted gauge field which is tractable both theoretically and numerically in lattice QCD. We circumvent path ordering without needing an additional path integral. By using Stokes' theorem, we can compute the Wilson Loop in terms of a surface integral over a restricted field strength, and show that the restricted field strength may be dominated by certain structures, which occur when one of the quantities parametrising the colour field $n$ winds itself around a non-analyticity in the colour field. If they exist, these structures will lead to a area law scaling for the Wilson Loop and provide a mechanism for quark confinement. We search for these structures in quenched lattice QCD. We perform the Abelian decomposition, and compare the electric and magnetic fields with the patterns expected theoretically. We find that the restricted field strength is dominated by objects which may be peaks a single lattice spacing in size or extended string-like lines of electromagnetic flux. The objects are not isolated monopoles, as they generate electric fields in addition to magnetic fields, and the fields are not spherically symmetric, but may be either caused by a monopole/anti-monopole condensate, some other types of topological objects or a combination of these. Removing these peaks removes the area law scaling of the string tension, suggesting that they are responsible for confinement.
Nigel Cundy; Y. M. Cho; Weonjong Lee
Mesoporous Silica Nanomaterials for Applications in Catalysis, Sensing, Drug Delivery and Gene Transfection
The central theme of this dissertation is represented by the versatility of mesoporous silica nanomaterials in various applications such as catalysis and bio-applications, with main focus on biological applications of Mesoporous Silica Nanospheres (MSN). The metamorphosis that we impose to these materials from catalysis to sensing and to drug and gene delivery is detailed in this dissertation. First, we developed a synthetic method that can fine tune the amount of chemically accessible organic functional groups on the pores surface of MSN by exploiting electrostatic and size matching between the cationic alkylammonium head group of the cetyltrimethylammonium bromide (CTAB) surfactant and various anionic organoalkoxysilane precursors at the micelle-water interface in a base-catalyzed condensation reaction of silicate. Aiming nature imitation, we demonstrated the catalytic abilities of the MSNs, We utilized an ethylenediamine functional group for chelating Cu{sup 2+} as a catalytic functional group anchored inside the mesopores. Thus, a polyalkynylene-based conducting polymer (molecular wire) was synthesized within the Cu-functionalized MSNs silica catalyst. For sensing applications, we have synthesized a poly(lactic acid) coated mesoporous silica nanosphere (PLA-MSN) material that serves as a fluorescence sensor system for detection of amino-containing neurotransmitters in neutral aqueous buffer. We exploited the mesoporosity of MSNs for encapsulating pharmaceutical drugs. We examined bio-friendly capping molecules such as polyamidoamine dendrimers of generations G2 to G4, to prevent the drug leaching. Next, the drug delivery system employed MSNs loaded with Doxorubicin, an anticancer drug. The results demonstrated that these nano-Trojan horses have ability to deliver Doxorubicin to cancer cells and induce their death. Finally, to demonstrate the potential of MSN as an universal cellular transmembrane nanovehicle, we anchored positively charged dendrimers on the surface of MSN and utilize them to complex cationic DNA. The p-EGFP-CI gene-coated MSN nanocomposite was able to transfect cancer cell lines, such as human HeLa and CHO cancer cell lines. The gene carrier ability of MSNs was further proved by transfecting primary cells and cotransfecting of two different genes in cancer cell lines. In sum, MSN are versatile partners in several types of applications.
Daniela Rodica Radu
The U.S. Department of Energy National Energy Technology Laboratory funded this research collaboration effort between NextEnergy and the University of Michigan, who successfully designed, built, and tested a reformer system, which produced highquality syngas for use in SOFC and other applications, and a novel reactor system, which allowed for facile illumination of photocatalysts. Carbon and raw biomass gasification, sulfur tolerance of non-Platinum Group Metals (PGM) based (Ni/CeZrO2) reforming catalysts, photocatalysis reactions based on TiO2, and mild pyrolysis of biomass in ionic liquids (ILs) were investigated at low and medium temperatures (primarily 450 to 850 C) in an attempt to retain some structural value of the starting biomass. Despite a wide range of processes and feedstock composition, a literature survey showed that, gasifier products had narrow variation in composition, a restriction used to develop operating schemes for syngas cleanup. Three distinct reaction conditions were investigated: equilibrium, autothermal reforming of hydrocarbons, and the addition of O2 and steam to match the final (C/H/O) composition. Initial results showed rapid and significant deactivation of Ni/CeZrO2 catalysts upon introduction of thiophene, but both stable and unstable performance in the presence of sulfur were obtained. The key linkage appeared to be the hydrodesulfurization activity of the Ni reforming catalysts. For feed stoichiometries where high H2 production was thermodynamically favored, stable, albeit lower, H2 and CO production were obtained; but lower thermodynamic H2 concentrations resulted in continued catalyst deactivation and eventual poisoning. High H2 levels resulted in thiophene converting to H2S and S surface desorption, leading to stable performance; low H2 levels resulted in unconverted S and loss in H2 and CO production, as well as loss in thiophene conversion. Bimetallic catalysts did not outperform Ni-only catalysts, and small Ni particles were found to have lower activities under S-free conditions, but did show less effect of S on performance, in this study. Imidazolium-based ILs, choline chloride compounds and low-melting eutectics of metal nitrates were evaluated, and it was found that, ILs have some capacity to dissolve cellulose and show thermal stability to temperatures where pyrolysis begins, have no vapor pressure, (simplifying product recoveries), and can dissolve ionic metal salts, allowing for the potential of catalytic reactions on breakdown intermediates. Clear evidence of photoactive commercial TiO2 was obtained, but in-house synthesis of photoactive TiO2 proved difficult, as did fixed-bed gasification, primarily due to the challenge of removing the condensable products from the reaction zone quickly enough to prevent additional reaction. Further investigation into additional non-PGM catalysts and ILs is recommended as a follow-up to this work.
Kelly Jezierski; Andrew Tadd; Johannes Schwank; Roland Kibler; David McLean; Mahesh Samineni; Ryan Smith; Sameer Parvathikar; Joe Mayne; Tom Westrich; Jerry Mader; F. Michael Faubert
Synthesis, Structure, and Reactivity ofbis(1,2,4-tri-t-butylcyclopentadienyl) Complexes of Cerium
The sterically demanding 1,2,4-tri-t-butylcyclopentadienylligand (1,2,4-(Me3C)3C5H2, hereafter Cp') has been used to preparemonomeric cerium metallocenes, Cp 2CeX (X = Cl, I, OSO2CF3), which areused to synthesize the benzyl, Cp'2CeCH2C6H5. The benzyl is a usefulstarting material for preparing other complexes in the Cp'2CeZ system (Z= BF4, F, NH2, C6H5, H). X-ray crystal structures of Cp'2CeOSO2CF3,Cp'2CeF, Cp'2CeCH2C6H5, and Cp'2CeH are presented. The benzyl slowlydecomposes in solution to toluene and a metallacycle,[Cp'][(Me3C)2C5H2(CMe2CH2)]Ce. The ring CMe3 groups of both themetallacycle and the hydride, Cp'2CeH, can be fully deuterated byprolonged exposure to C6D6, providing a useful labeling tool inmechanistic studies.The hydride activates C-F and/or C-H bonds influorobenzenes, C6HxF6-x , x = 0-5. The reactions are selective, with theselectivity depending on the presence of two fluorines ortho to thereaction site more than on the type of bond activated. Complexes of thetype Cp'2CeC6HxF5-x , x = 0-4, are formed as intermediates, which slowlydecompose in solution to Cp'2CeF and fluorobenzynes, C6HxF4-x, x = 0-4,which are trapped. The rate at which Cp'2CeC6HxF5-x complexes decomposeincreases as the number of fluorines decreases. Complexes with oneortho-fluorine decompose much faster than those with two ortho-fluorines.The metallacycle activates only C-H bonds in fluorobenzenes, permittingthe synthesis of specific Cp'2CeC6HxF5-x complexes. The crystal structureof Cp'2CeC6F5 is presented. The hydride and the metallacycle react withfluoromethanes, CH4-xFx, x = 1-3, through postulated Cp'2CeCH3-xFxintermediates to generate Cp'2CeF and other products. The other products,CH4, tri-t-butylbenzenes, tri-t-butylfluorobenzenes, and a presumedmetallocene cerium fluoride with one Cp' and one (Me2EtC)(Me3C)2C5H2ligand, suggest a decomposition pathway for Cp'2CeCH3-xFx , x = 1-3, thatinvolves carbenes or carbenoids, which are trapped. The hydridepolymerizes ethylene, but hydrogenates other olefins. The metallacycleactivates C-H bonds in olefins and aromatics to generate new complexeswith Ce-C bonds. The hydride reacts with one equivalent of CO in pentaneto generate (Cp'2Ce)2CH2O, whose crystal structure shows the presence ofa bridging dianionic formaldehyde ligand. (Cp'2Ce)2CH2O reacts H2 to givethe hydride and Cp'2CeOMe, or with a mixture of H2 and CO to generateCp'2CeOMe exclusively. (Cp'2Ce)2CH2O or the hydride can react with anadditional equivalent of CO to generate dimeric enediolate,(Cp'2CeCHO)2.
Werkema, Evan L.
Bulk gold catalyzed oxidation reactions of amines and isocyanides and iron porphyrin catalyzed N-H and O-H bond insertion/cyclization reactions of diamines and aminoalcohols
This work involves two projects. The first project entails the study of bulk gold as a catalyst in oxidation reactions of isocyanides and amines. The main goal of this project was to study the activation and reactions of molecules at metal surfaces in order to assess how organometallic principles for homogeneous processes apply to heterogeneous catalysis. Since previous work had used oxygen as an oxidant in bulk gold catalyzed reactions, the generality of gold catalysis with other oxidants was examined. Amine N-oxides were chosen for study, due to their properties and use in the oxidation of carbonyl ligands in organometallic complexes. When amine N-oxides were used as an oxidant in the reaction of isocyanides with amines, the system was able to produce ureas from a variety of isocyanides, amines, and amine N-oxides. In addition, the rate was found to generally increase as the amine N-oxide concentration increased, and decrease with increased concentrations of the amine. Mechanistic studies revealed that the reaction likely involves transfer of an oxygen atom from the amine N-oxide to the adsorbed isocyanide to generate an isocyanate intermediate. Subsequent nucleophilic attack by the amine yields the urea. This is in contrast to the bulk gold-catalyzed reaction mechanism of isocyanides with amines and oxygen. Formation of urea in this case was proposed to proceed through a diaminocarbene intermediate. Moreover, formation of the proposed isocyanate intermediate is consistent with the reactions of metal carbonyl ligands, which are isoelectronic to isocyanides. Nucleophilic attack at coordinated CO by amine N-oxides produces CO{sub 2} and is analogous to the production of an isocyanate in this gold system. When the bulk gold-catalyzed oxidative dehydrogenation of amines was examined with amine N-oxides, the same products were afforded as when O{sub 2} was used as the oxidant. When the two types of oxidants were directly compared using the same reaction system and conditions, it was found that the oxidative dehydrogenation of dibenzylamine to Nbenzylidenebenzylamine, with N-methylmorpholine N-oxide (NMMO), was nearly quantitative (96%) within 24 h. However, the reaction with oxygen was much slower, with only a 52% yield of imine product over the same time period. Moreover, the rate of reaction was found to be influenced by the nature of the amine N-oxide. For example, the use of the weakly basic pyridine N-oxide (PyNO) led to an imine yield of only 6% after 24 h. A comparison of amine N-oxide and O2 was also examined in the oxidation of PhCH{sub 2}OH to PhCHO catalyzed by bulk gold. In this reaction, a 52% yield of the aldehyde was achieved when NMMO was used, while only a 7% product yield was afforded when O{sub 2} was the oxidant after 48 h. The bulk gold-catalyzed oxidative dehydrogenation of cyclic amines generates amidines, which upon treatment with Aerosil and water were found to undergo hydrolysis to produce lactams. Moreover, 5-, 6-, and 7-membered lactams could be prepared through a one-pot reaction of cyclic amines by treatment with oxygen, water, bulk gold, and Aerosil. This method is much more atom economical than industrial processes, does not require corrosive acids, and does not generate undesired byproducts. Additionally, the gold and Aerosil catalysts can be readily separated from the reaction mixture. The second project involved studying iron(III) tetraphenylporphyrin chloride, Fe(TPP)Cl, as a homogeneous catalyst for the generation of carbenes from diazo reagents and their reaction with heteroatom compounds. Fe(TPP)Cl, efficiently catalyzed the insertion of carbenes derived from methyl 2-phenyldiazoacetates into O-H bonds of aliphatic and aromatic alcohols. Fe(TPP)Cl was also found to be an effective catalyst for tandem N-H and O-H insertion/cyclization reactions when 1,2-diamines and 1,2-alcoholamines were treated with diazo reagents. This approach provides a one-pot process for synthesizing piperazinones and morpholinones and related analogues such as quinoxalinones and benzoxazin-2-ones.
Klobukowski, Erik
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