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Sequencing of pediatric gliomas has identified missense mutations Lys27Met (K27M) and Gly34Arg/Val (G34R/V) in genes encoding histone H3.3 (H3F3A) and H3.1 (HIST3H1B). We report that human diffuse intrinsic pontine gliomas (DIPGs) containing the K27M mutation display significantly lower overall amounts of H3 with trimethylated lysine 27 (H3K27me3) and that histone H3K27M transgenes are sufficient to reduce the amounts of H3K27me3 in vitro and in vivo. We find that H3K27M inhibits the enzymatic activity of the Polycomb repressive complex 2 through interaction with the EZH2 subunit. In addition, transgenes containing lysine-to-methionine substitutions at other known methylated lysines (H3K9 and H3K36) are sufficient to cause specific reduction in methylation through inhibition of SET-domain enzymes. We propose that K-to-M substitutions may represent a mechanism to alter epigenetic states in a variety of pathologies.
Somatic mutations in genes encoding proteins that modify chromatin dynamics frequently contribute to tumorigenesis (1). Mutations in subunits of the Polycomb repressive complex 2 (PRC2) are often associated with tumor progression (2). PRC2 normally helps maintain epigenetic gene silencing and X chromosome inactivation through enzymatic di- and trimethylation of K27 on histone H3 (3). In addition to enzymatic machinery, histone H3 missense mutations in pediatric gliomas represent direct evidence that alterations of the histones themselves can promote cancer. In two pediatric brain cancers, diffuse intrinsic pontine gliomas (DIPGs) and supratentorial glioblastoma multiforme (GBMs), 60% of patients studied exhibited one of two mutually exclusive mutations in either H3F3A, one of two genes encoding the histone H3 variant H3.3, or HIST1H3B, one of several genes encoding H3.1 (4–6). The K27M mutation occurring in either H3F3A or HIST1H3B was observed in nearly 80% of DIPGs, and 22% of non–brain stem gliomas (6).
We sought to determine whether DIPG samples that contain the K27M mutation exhibit global changes in key regulatory histone modifications. Immunoblots with antisera raised against the K27M substitution (fig. S1A) indicated the presence of H3 K27M protein in DIPG samples containing H3F3A (H3.3) or HIST3H1B (H3.1) alleles (Fig. 1A). DIPG tumors containing H3K27M mutations exhibited both a decrease in H3 with trimethylated lysine 27 (H3K27me3) and a modest increase in amounts of H3 with acetylated lysine 27 (H3K27ac) by immunoblot with modification-specific antisera (Fig. 1, A and C). Quantification of H3K27me3 by immunohistochemistry demonstrated that K27M mutant DIPGs contained significantly less H3K27me3 than non-K27M mutant DIPGs (Fig. 1D). The H3.1/3 K27M protein is 3.63% (±0.33) to 17.61% (±1.11) of total H3 in human DIPG samples, as measured by quantitative mass spectrometry (fig. S1B). Two histone modifications related to transcription and/or activation (H3K4me3 and H3K36me3) were similar in DIPG samples regardless of tumor genotype, which could be used to argue that global changes in posttranslational modifications were specific to H3K27. Using a platelet-derived growth factor (PDGF)–induced brain stem glioma model to characterize this mutation in vivo (7), we found that transgenic H3.3K27M was sufficient to increase H3K27ac and to significantly reduce H3K27me3 (Fig. 1, B to D). Expression of H3.3K27M with p53 loss in nestin progenitors of the neonatal mouse brain stem was not sufficient to generate gliomas but did induce proliferating ectopic cell clusters in 72% (21 out of 29) of the mice (fig. S1C), whereas expression of the wild-type H3.3 with p53 loss (n = 8) in nestin progenitors of the neonatal mouse brain stem did not result in the induction of ectopic proliferating cell clusters (fig. S1D).
To investigate the mechanism by which H3K27M decreased overall H3K27me3, we generated stable human embryonic kidney–293T (HEK293T) cell lines that express FLAG- and hemagglutinin (HA) epitope–tagged wild-type histone H3.3 or K27M and G34R/V mutants, which contributed to about 1% of total cellular histone H3, as measured by immunoblot. Cells expressing the H3K27M mutant histone exhibited a profound reduction in H3K27me2/3, with little changes in the amounts ofH3K4me3 or H3K36me3 (Fig. 2A). This reduction was specific to the H3K27M mutation, as amounts of H3K27me2/3 remained unchanged in H3.3G34R/V transgenic cell lines. We did not observe change in the amounts of PRC2 complex components in H3.3K27M, PDGF-induced glioblastoma cell lines (fig. S2A).
The heterozygous and invariant nature of the lysine-to-methionine mutation at residue 27 in nearly 80% of pediatric DIPGs strongly suggests that this specific amino acid substitution imparts a unique gain-of-function to the mutant histone. To further test the specificity of this substitution, we performed a survey of all amino acid substitutions at H3K27. Nearly all substitutions had little effect, if any, on the amounts of K27me3, with the exception of methionine, and to a lesser extent isoleucine (Fig. 2B).
The global reduction in H3K27me2/3 suggested that the H3K27M transgene reduced methylation on endogenous wild-type H3 histones. Indeed, purified heterotypic mononucleosomes (1:1 ratio of H3.3-FLAG-HA: endogenous H3.3), oligonucleosomes containing H3K27M, or wild-type oligonucleosomes from K27M-expressing cells displayed a marked decrease in H3K27me3 on the endogenous H3 protein (fig. S2B). Concomitantly, these nucleosomes exhibited a modest increase in the acetylation of H3K27 (H3K27ac) on the untagged H3 in the heterotypic K27M nucleosomes (Fig. 2C), and, similar to the modification pattern observed on mononucleosomes, oligonucleosome arrays showed elevated H3K27ac when they contained H3.3K27M (Fig. 2D).
We investigated amounts of H3K36me3 in cell lines carrying H3.3G34R/V mutations to determine whether these mutations behave similarly to H3K27M. Although overall amounts of H3K36me3 remained unchanged in H3.3G34R/V cell lines, a marked loss of H3K36m3 was exclusive to the epitope-tagged H3.2/3 of purified mono- or oligonucleosomes (Fig. 2, B and C). The epitope-tagged H3 exhibited a decrease in K36me2 (~2.7-fold) and K36me3 (~18.5-fold) on the G34R/V mutants, compared with wild type, as measured by mass spectrometry (fig. S2C).Heterotypic H3.3 G34R or G34V mononucleosomes were methylated to a lesser extent by recombinant SETD2 in vitro, which indicated that nonglycine residues at position 34 on the substrate peptide decreases SETD2 methylation at K36 (fig. S2, D and E).
H3K27me3 peptides allosterically stimulate PRC2 methyltransferase activity on nucleosome substrates (8, 9), and we found that incubation of 10 or 100 µM of H3K27me3 peptide strongly stimulated PRC2 activity toward mononucleosome or oligonucleosome templates (Fig. 3A). Heterotypic H3K27M mono- or oligonucleosomes containing H3K27M (fig. S3, A and B) were methylated to a lesser extent than wild-type nucleosome substrates when purified human PRC2 was used (Fig. 3A and fig. S3C). This reduction in PRC2-dependent signal was unique to chromatin containing H3K27M, as heterotypic K27A, K27R, or K27Q mononucleosomes showed no decrease in methylation on the endogenous histone (Fig. 3B).
The reduced methylation on nucleosome templates suggested that the K27M peptide might interfere with PRC2 activity normally stimulated by H3K27me3. Incubation of K27M peptide in trans decreased PRC2 activity on wild-type nucleosomes to below the no-peptide signal (Fig. 3C), whereas the unmodified or K27ac peptide exhibited little stimulation relative to no-peptide control (Fig. 3C). The H3K27M peptide reduced PRC2-dependent methylation by 6.2-fold at 45 µM as measured by scintillation counting (Fig. 3D). Peptide titration showed that µM concentrations of H3K27M, but not the K27ac peptide, could inhibit PRC2-dependent methyltransferase activity in a dose-dependent manner (Fig. 3E and fig. S3, D and E).
We synthesized biotinylated H3 peptides carrying either the diazirine-containing methionine isostere l-photo-Met at position 27 (peptide 1) or a benzophenylalanine residue at position 31 that retains the K27M mutation (peptide 2) (fig. S4, F and G).Upon irradiation, both peptides cross-linked effectively to the EZH2 subunit and less so to the AEBP2 and EED subunits (Fig. 4A and fig. S4E), which suggested that K27M peptides inhibit PRC2 through interaction with the EZH2 active site. Although the EED subunit is needed for enzymatic activity and K27me3 allosteric activation (8), we did not observe interaction between EED and H3K27M peptides by surface plasmon resonance or peptide pull-down assays (fig. S4, A to D). We additionally found the K27M peptide could inhibit a PRC2 complex that contained a mutant EED (Y365A) that cannot interact with K27me3 (fig. S5A).
Titration of K27M peptide to in vitro methylation reactions revealed a median inhibitory concentration (IC50) of 5.9 µM [95% confidence interval (CI) of 1.10 to 6.42]. To evaluate whether the thioether moiety of methionine was required for inhibition of PRC2, a norleucine derivative (K27Nle) was prepared. The K27Nle variant proved to be an even better inhibitor of PRC2 (Fig. 4B) (IC50 for K27Nle = 0.85 µM) (95% CI: 0.57 to 1.27) (fig. S6A). Peptides containing Lys27 replaced by Ile inhibited PRC2 to a lesser extent than K27M (IC50 for K27I = 8.9 µM (95% CI: 4.12 to 11.2), whereas Lys27 replaced by Leu had no inhibitory effect on the amounts of H3K27me3 in vivo or PRC2 in vitro (Fig. 4C and fig. S6, B to D). Thus, a long, hydrophobic residue suffices for EZH2 binding, and methionine—and to a slightly lesser extent isoleucine—represents the ideal biochemically accessible choices.
SET domain histone methyltransferases contain several highly conserved aromatic residues that serve in substrate binding and catalysis. The Tyr641 residue in EZH2 is hypothesized to restrict higher-order lysine methylation by acting as a steric gatekeeper (10, 11). Recombinant Y641N EZH2-containing PRC2 was less sensitive to inhibition by the H3K27M peptide compared with wild-typePRC2 (Fig. 4, D to F, and fig. S6,E and F), which furthers the argument that hydrophobic interactions between the methionine side chain and aromatic residues in the EZH2 active site are important for K27M inhibition of PRC2.
We tested whether the highly conserved active sites of other SET-domain proteins may be similarly sensitive tomethionine substitution at their cognate peptidyl-lysine substrate by constructing H3.3 transgenes containing methionine at K4, K9, and K36 (12). H3K9M and H3K36M transgenes decrease overall amounts of H3K9me2/3 and H3K36me2/3, respectively (Fig. 4G and fig. S7A). Although H3K4M transgenes did not diminish overall amounts of H3K4me2/3, the lack of reduction in methylation may be a consequence of reported inhibition of LSD1/2 histone H3K4me3 demethylases by H3K4M peptides (13). Histone H3K9M (1–20) peptides effectively inhibit recombinant histone H3K9 methyltransferases SUV39H1 and G9a (Fig. 4H) [IC50 for K9M = 2.2 µM for SUV39H1 (95% CI: 1.7 to 2.6); IC50 for K9M = 3.6 µM for G9a (95% CI: 2.1 to 5.9)] (fig. S7, B and C). These data argue that the H3K9-specific SET-domain inhibition likely causes the reduction ofH3K9me2/3 in H3.3K9M-expressing cells.
To determine whether the chromatin context of K-to-M mutants is important for in vivo inhibition of trimethylation, we placed the H3 tail (amino acids 1 to 42) onto the core domain (amino acids 23 to 102) of histone H4-HA-FLAG.H3K9me3 was reduced in cells expressing the K9M H3–H4 hybrid (fig. S8A). However, K27M and K36M failed to reduce H3K27me3 and K3K36me3 when expressed in the context of H3-H4 hybrid transgenes (fig. S8, B, C, and D). These results argue that SET-domain protein interactions with non–N-terminal nucleosomal surfaces are important for the full inhibitory activity of some K-to-M, but not all, mutants in vivo.
In summary, the data shown here provide compelling evidence that a missense histone mutation can dramatically alter nuclear biochemical processes through a gain-of-function mechanism. Moreover, our data indicate that K-to-M mutations target the active sites of diverse SET domain–containing methyltransferases and, thereby, effectively compete with substrate binding and turnover. Notably, in their proper chromosomal context, K-to-M mutant histones that make up only a few percent of total histones suffice to prevent global methylation at their cognate residues. This reduction in histone methylation is expected to disrupt positive-feedback loops that contribute to the regulation of PRC2 and thus to enhance the inhibitory effect of mutant histones. We propose a model whereby aberrant epigenetic silencing through H3K27M-mediated inhibition of PRC2 activity promotes gliomagenesis. The broadly adaptable, yet highly specific, inhibition of SET-domain proteins through K-to-M mutation offers the intriguing possible existence of other etiological missense mutations in histones. Additionally, our work has uncovered a potentially useful mechanism to exclusively inhibit individual SET-domain methyltransferases, and conceivably other chromatin-modifying enzymes, implicated in a variety of malignancies.
B.A.G. acknowledges funding from NIH Innovator grant (DP2OD007447), Office of the Director, NIH. O.J.B. is supported by the U.S. Department of Defense; The Pediatric Brain Tumor Foundation; and the Damon Runyon, Rory David Deutsch, and Cristian Rivera Foundations. C.D.A. acknowledges funding from NIH (GM040922) and Starr Cancer Consortium (grant SCC I6-A614). We thank D. Reinberg for reagents, and EMD Millipore for its role in H3K27M antibody generation.
Supplementary Materials
Materials and Methods
Supplementary Text
Figs. S1 to S8
Reference (14)
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Large Lakefront House-Perfect for family reunions
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Description from the owner
Description from the owner
Bedrooms: 5/
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Type: House
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Ginny E.
Ginny E.
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HBO presents fascinating profile of former New York Jets quarterback Joe Namath
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Men's Hockey Ends in 2-2 Tie at Colby
Joe Brock scored both of Amherst's goals in a 2-2 tie at Colby.
From a Colby College release
WATERVILLE, ME - The 7th-ranked Amherst College men's hockey team saw a 2-1 lead erased when Colby's Michael Smigelski scored with just three minutes left in regulation as the two teams settled for a 2-2 tie Saturday at Alfond Rink.
In a game where both goalies played key roles, only two players managed goals on the day. Smigelski scored his ninth and 10th goals of the season for Colby (10-5-4, 6-5-4 NESCAC), while Amherst's Joe Brock (Cumming, GA) also scored his ninth and 10th goals of the season.
Colby goaltender Cody McKinney made 17 of his 33 saves in the second period and had a pair of stops in the overtime session. Amherst goalie Cole Anderson (Sylvan Lake, Alberta) was up to the task with five saves in overtime and nine in each of the three periods of play for 32 stops. Anderson helped the Lord Jeffs move to 14-3-3 overall and 9-3-3 in the NESCAC.
Smigelski scored from Patrick Bursee and Michael Doherty at 12:07 of the first period on the power play for the lone goal of the opening 20 minutes.
Brock scored two straight power play goals over two periods to put the Lord Jeffs up 2-1. Matthew Rhone (Dedham, MA) and Jamie Hawkrigg (Waterdown, Ontario) had the assists on both goals.
Bursee picked up his second assist of the day and Nick Kondiles had the other assist on Colby's tying goal with three minutes to play.
The overtime session was an eventful five minutes, with each team taking a penalty. Both goalies also stopped breakaway attempts when their team was on the power play. The Lord Jeffs were 2-for-6 with the extra man and Colby was 1-for-4.


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After six years at George Washington, John Creighton is bidding farewell to the Eagles.
Father Judge president Rev. Joseph Campellone has stepped down to undertake a national study of Catholic education.
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Each country uses different terminology to talk about overseas placements. To further confuse matters, what goes in one country could mean something entirely different in another. It is very easy to get confused!
We have chosen to use the term "internships" to describe our short-term, structured healthcare rotations. They are suitable for students traveling as a credited part of their university course, or for those looking for work experience during their holidays. They are also suitable for professionals, and will be tailored to suit skill level and areas of interest.
We are able to arrange a wide range of medical placement options, from large city hospitals to rural primary healthcare clinics. Opportunities are available in almost any clinical speciality and it's feasible to combine more than one area to gain the best possible experience.Read more
Work the World nursing internships are specifically designed to suit your needs as a nursing student wanting practical experience, but also crucially meet the requirements of your university or college.Read more
Midwives are in significant demand in the destinations in which we work. With placement opportunities in large government hospitals, specific maternity hospitals and even remote village clinics, a midwifery internship with Work the World is an unparalleled opportunity to hone your skills and broaden your experience.Read more
Physical Therapy
Physical therapy placements abroad offer exceptional hands-on opportunities. Hospitals in developing countries are often short staffed with high patient loads. As such students find themselves involved with treatment and patient care very quickly.Read more
As dental care is generally much less accessible in the developing world, the dental units with which we work with are extremely busy. Serving large catchment areas and with patients often presenting at a very late stage, these dental internships are an eye-opening and worthwhile experience.Read more
Radiography and radiology internships are the latest addition to the range of clinical placements available through Work the World. These internships are a fantastic opportunity to travel the world, often returning to back-to-basics diagnostic skills, but certainly gaining a diverse and rewarding expereince.Read more
Our Pharmacy internships are individually tailored to encompass working in dispensaries and attending ward rounds with multidisciplinary teams to finalise treatment plans. These overseas experiences will offer you an amazing cultural experience and will allow you to gain an insight into the delivery of care in resource poor settings.Read more
First-HandExperiencesRead More
There is a vast difference in Health care procedure in Nepal which was a huge cultural shock at first.
Emma Lutkin and Tammy Hanson, University of Hull 2015Read More
In A&E we saw a variety of patients 99% of whom were brought in from motor bike related incidents.
Lee Chester, University of Central Lancashire 2015Read More
We as students are there to learn and not teach.
Tonia Dunn, University of Brighton 2015Read More


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Government - Page 14
Equal Pay For Equal Work — Really?
Boston Marathon Bombing: One Year Later
The Assassination of Lincoln
Are Some People Above The Law?
Companies We Love to Hate
Money In Politics: What Does It Buy?
Do We Need A "Marshall Plan" for America?
Morning Show EXCLUSIVE: Conversation with Senator Jon Tester [AUDIO]
In this month's conversation Senator Tester covers the topics of: 'Equal Pay For Equal Work,' minimum wage, US Brass and much more!
THANK YOU to everyone who emailed questions!


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* Sit-n-Go poker tournaments
* Poker Ring Games
* Free daily Gold
* Lottery Draw
* 200+ Virtual goods you can send people on tables
* Live Hold'em Poker Pro is a Poker game for entertainment uses only.
* The game does not offer an opportunity to win real money. Practice or success at social casino gaming does not imply future success at real money gambling.
* Live Hold'em Poker Pro is intended for use by those who are 21 or older.
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What's New
World Series of Poker – WSOP
● MULTI-LEVEL TOURNAMENTS – Atlantic City, Paris, Sydney, Tokyo, London and Las Vegas resorts are waiting to host you! Take a seat and play like a PRO!
● WSOP RINGS – Win tournaments to earn WSOP rings and climb the leaderboard! What's more fun than sitting at the top?
● OFFICIAL VEGAS EXPERIENCE – Try your hand at Texas Hold'Em, Omaha, Tournaments, and more for FREE.
● GAIN A COMPETITIVE EDGE – Improve your game with the most extensive stats tracking in any poker game!
● MORE FREE CHIPS, MORE OFTEN – Collect FREE chips every four hours!
● PLAY WITH POKER BUDDIES – Invite your friends, kick back and make it a poker night anytime, anywhere on mobile devices, tablets and web.
● CONTINUOUS PLAY – Start playing on your mobile phone or tablet and continue on the web with the same bankroll.
● GUEST MODE – Rock the tables and play anonymously.
● SLOTS MINI GAME – Spin and win chips in between hands with the slot machine.
● FACEBOOK CONNECT BONUS – Pad your bankroll with $15,000 additional chips when you connect your account to Facebook!
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Call information is required to provide you with the ultimate customer support!
This product is intended for use by those 21 or older for amusement purposes only.
Practice or success at social casino gaming does not imply future success at real money gambling.
Governor of Poker 2 - HOLDEM
Millions of poker players have enjoyed Governor of Poker, without an internet connection.
With an easy Texas Holdem poker tutorial for players that don't know how to play poker, but want to learn poker and good opponents for star poker players with real poker skills!
The poker chips you win are required to buy houses, win transportation, play against advanced poker AI opponents, win Texas and beat the new Governor of Poker.
•Get ready for many hours and hours of Hold'm Poker play:
- Over 80 challenging poker players to beat;
- 27 stunning card saloons in 19 amazing Texas Holdem cities;
- Get hold of the five big poker assets.
•Amazing Texas Poker AI Engine:
A great new poker engine will challenge poker beginners and world poker champions alike.
Refine your tactics to match the countless poker playing styles of your opponents and watch them go "Steamy" and Tilt after showing off your great card bluffs!
Players will play better in each new city and poker tournament, no cheating allowed!
•Full Story:
Governor of Poker 2 starts where the first game ended.
A new Dallas government decided to put a ban on all Texas Holdem poker games and now considers the game to be illegal.
Time to take matters in your own hands and prove them wrong! Poker isn't a game of luck, but requires poker skill.
•Play Always and Everywhere Offline Poker, no internet connection required:
Because there is no live internet connection needed to play a good game of Texas hold'em poker, you can just play Governor of Poker 2 offline anywhere you want!
Don't wait for human players in multiplayer poker games, that don't respond or leave the pokergame or go allin all the time. Just play this offline poker game !
•Customize poker characters:
Prove you are a bigshot by customizing your poker style to fit your reputation. Be sure to visit one of the many great hat shops across Texas and get yourself the poker deluxe hat of your dreams!
The game includes HD Poker graphics for a great experience on all Android phones and tablets.
Travel through Texas by Train, Casino Boat or Stage Coach and play poker whilst on your way to the next poker city in Texas.
Every city has lots of exciting cash games and big poker tournaments with even bigger Chip prizes, competition and bigger tournaments. You'll experience more checks, calls, raises, folds and all-ins than you can imagine!
Enjoy sit-n-go tournaments, Shootout tournaments, Bounty tournaments, Cash games.
You don't need an internet connection and don't have to wait for other poker players, it's an offline poker game.
Have you always been a Texas holde'm pokee fanatic? You'll love Governor of Poker 2! What are you waiting for partner? Click install, download and prove you're worthy of the great poker title: GOVERNOR OF POKER !
**** Governor of Poker 2 Reviews ****
- Gamezebo: "Makes poker accessible without being too simple. Great sense of personality. Excellent poker tutorial.. It's a Royal Flush."
- Jayisgames: "Governor of Poker 2 is well-made, highly accessible, and surprisingly addictive for all kinds of players."
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- Miniclip 5 stars out of 5: "Howdy! Finally it's here, Governor of Poker 2! Packed with lots and lots of poker extra's! More cities to conquer and tournaments to play!"
This pokergame is FREE to play in Amarillo, but will require IAP to enjoy the full game. :)
Please contact email@example.com if you have any issues or suggestions, we would love to help!
You can also follow us at Facebook : https://www.facebook.com/governorofpoker2
Go download Governor of Poker 2 and enjoy the Texas Holdem Poker Adventure!
Texas Poker
You join a game, but you don't have anything good on your hands. Everyone has folded except you and one other player. You take another look at your cards. Can you bluff your way through? Your device vibrates reminding that you have to make a decision, now.
Texas Poker holds plenty of exciting actions for players of all levels. Play, bluff, win, chat with others at the table, buy them gifts. You were impressed by the way your opponent had played a hand, or maybe you want to celebrate your own victory? Then treat him a whisky or pamper yourself with an expensive cuban cigar! Gain levels by winning hands, check out other player's stats and level trying to guess how good they are. Lost all your winnings because of a bad hand? Not a problem, wait for a daily lottery to get some more chips or buy them in appStore even without leaving the table. But what if you are new to poker and don't even know basics? Do not worry, we have an interactive tutorial which will quickly help you to get into the game. Think you are already good enough? Then just choose a table and get ready for tough competition!
* Absolutely free to play, no registration required
* Thousands of players online daily
* Easy-to-use, attractive interface: one tap call, raise, check, fold
* Invite your friends to join you via E-mail and Facebook and get bonuses
* Chat with other players, buy gifts, earn achievements
* In app tutorial
* Take part in Sit'n'Go tournaments
If you love card games, come and join Pokerist: Texas Poker by KamaGames. Getting in is easy! Just click on the button and download the app now for free.
See you at the tables!
This game is only available to people of legal age. The game offers no possibility of winning money or anything of value. Success in playing this game does not imply your success in a similar real-money casino game.
World Poker Club™
Find yourself in the world of bets, stakes and huge winnings! Play your favorite poker games – the Texas Hold 'Em and Omaha – and make sure to compete for the bankroll of our Weekly tournament. Finally, enjoy the stylish interface and friendly atmosphere designed for perfect mobile gaming!
To hype up the experience and thrill, we've prepared all sorts of surprises and bonuses for our players: complete themed collections by playing in different poker rooms and exchange them for game currency; send gifts to your friends and receive kind gestures in return; use the chat to talk to other players; and aim high in the top charts of our club. Prove to millions of other players that you're on the very top of your poker game.
Let's play! Once you've joined, you'd never want to leave!
• Free chips and other bonuses
• Poker classics: Texas Hold 'Em and Omaha
• Weekly tournaments
• Sit-n-Go tournaments
• Play as a guest or via your accounts at Facebook or Google+
• Player ratings
• Stylish and intuitive interface
• Gifts, awards and collections
Poker Brasil
Graças a plataforma completamente integrada ao Facebook, fica fácil jogar com seus amigos e convidá-los para o jogo.
Plataforma compartilhada com o Facebook
Várias mesas diferentes de acordo com o nível de cada jogador.
Milhares de jogadores reais online todos os dias
Dragonplay Poker Texas Hold'em
Play Dragonlay poker, Texas Hold'em Poker, for free against millions of real users worldwide. Register with your Facebook account or your email and join the Poker madness today. Played by more than 25,000,000 Android users. The masters of Poker play here!
Get Up to $500,000 free chips when opening an account for the first time!
Game features:
* Live Chat
* Fast Tables
* Shootout poker tournament mode
* Sit-n-Go poker tournament Mode
* Poker Ring Games
* Free daily Gold
* 200+ Virtual goods you can send people on tables
* Facebook connect for fast registration (optional)
* Dragonplay Poker Pro is a Poker game for entertainment uses only.
* The game does not offer an opportunity to win real money. Practice or success at social casino gaming does not imply future success at real money gambling.
* Dragonplay Poker Pro is intended for use by those who are 21 or older.
Governor of Poker 3
Becoming a poker star is a long journey. You'll start as a rookie and work your way up to become a VIP poker player and a high roller.
• Only app with 6 different types of poker variants including Turbo cash games, Sit & Go tournaments, heads-up, push or fold, Big Win and royal poker.
• Play blackjack.
• Enjoy our FREE welcome package of chips, gold and a hat.
• Get a FREE chips bonus every 4 hours!
• Invite your friends to play with you at the same table!
• Complete achievements and win gold coins and XP points.
The games are intended for an adult audience. (e.g Intended for use by those 21 or older)
The games do not offer "real money gambling" or an opportunity to win real money or prizes. (e.g the game is for amusement purposes only).
Practice or success at social casino gaming does not imply future success at "real money gambling".
Full Tilt Poker - Texas Holdem
Fun. Exciting. Tailored for mobile.
The Full Tilt mobile app was named 'Best Poker App' at the IGA Gaming App Awards 2014.
The great thing about the Full Tilt mobile app is that it allows you to enjoy your favorite games anytime, anywhere. Jackpot Sit & Go Tournaments, Rush Poker – they're all there.
You can access Full Tilt's games from any device with Android 2.3.3 or higher. Please note that the Full Tilt Poker.net app is only for play-money players aged 18 years and up.
Check out what's available on Full Tilt's mobile app:
• Never miss a promotion or special offer with our Push Notifications, keeping you in the game at all times
• Hit No Limit Texas Hold'em and Pot Limit Omaha tables
• Win a share of up to 2,000 times your buy-in with Jackpot Sit & Go Tournaments
• Play Sit & Go Tournaments: choose between 6-Max or Heads-Up
• Also available: Rush Poker, Adrenaline Rush and Ring Game tables
• Play at a wide range of Play Chip stake levels
• Buy Play Chip bundles and become an instant high roller
• Fully optimized for mobile devices
• Log in using your existing Full Tilt Player ID and Password or create an account if you're a new player
Activate Push Notifications to ensure nothing slips through your fingers. It hurts to miss out on great promotions or offers, but with your Push Notifications on, you'll never miss a beat. In fact, some announcements will only be made via Push Notification, so activate it to keep up with exclusive offers you won't hear about anywhere else.
Join our poker community on social media and connect with poker players from around the world.
Play anytime, anywhere – download the Full Tilt mobile app now.
• Wi-Fi, 3G or 4G Internet connection
• Android 2.3.3 or higher
• Minimum screen resolution of 800x480
• English
• French (Canadian)
• German
• Dutch
• Portuguese (Brazil)
• Russian
• Swedish
• Norwegian
• Finnish
• Spanish
• Hungarian
• Polish
• Ukrainian
• Czech
• Slovak
• Croatian
Full Tilt Poker.net is a fun, safe place to play poker. We're proud to provide players with the best mobile software available, boasting innovative features and regular improvements.
Full Tilt Poker.net is part of the Rational Group, one of the largest and most respected online gaming companies in the world, which prides itself on providing the most secure environment possible for playing online. Full Tilt Poker.net offers the best in on-line gaming: a wide variety of exciting games and 24/7 customer support.
Poker Shark
Play for keeps as you go head to head with over 20,000,000 players worldwide!
* Up to 10,000 free chips everyday
* Thousands of players online.
* Weekly Texas Hold'em tournaments.
* Up to 9 players per table.
* Live in-game chat
Get in the action today!
Tien Len - Southern Poker
Tien len ("Tiến lên") ,considered the national card game of Vietnam , is a game intended and best for 4 players.
Texas Poker Lite
App is absolutely free to play
Hundreds of thousands of players playing the app right now
Use one account to play on mobile devices and in social networks
Multi screen interface allows to play at two tables at once and quickly switch between game modes
Add other players to friends, send them personal messages; or chat right at the table, buy gifts for friends and rivals alike
Use innovative voice input interface
Try VIP status giving you access to exclusive features
Sit'n'Go and Shootout tournaments
Participate in daily and weekly free chips promotions
Play in your native language (19 languages total)
Buy chips for yourself and your friends right at the table without interruptions
Get straight into the game without additional settings with "Play now" button
If you love poker, come and join the club for devoted and occasional poker-players alike. Getting in is easy. Just click on the button and download the app now for free.
This game is only available to people of legal age. The game offers no possibility of winning money or anything of value. Success in playing this game does not imply your success in a similar real-money casino game.
Poker España
1. Aplicación gratuita, puede jugar con su cuenta de Facebook tambien!
2. "sit and go" y torneos diarios!
3 Miles de jugadores en línea todos los días!
4 Juegue con sus amigos y haga nuevos amigos aquí!
5 Ver dónde están jugando sus amigos y unase a ellos en cualquier momento!
Poker Texas Русский
Насладитесь держать власть мира В ОДНОЙ РУКЕ, присоединяйтесь к нам!
Poker Arena: texas holdem game
Your hand is ready — start playing poker right now!
Get your friends and play with them stunningly addictive Texas Hold`Em poker, rendered with amazing graphics and user-friendly interface — just like in a real poker casino!
Win, bluff and talk with other poker players via in-game chat! And, of course, give them poker gifts and presents!
Unfamiliar with rules of Texas Holdem poker? Not a problem! Poker Arena works great for both newbies and pros! Tutorial & virtual assistant along with table of poker combinations plus visual demo of the strength of your current poker hand!
Finally, you can play Poker Arena offline: hone your poker skills in the dramatic single player poker campaign called "Trixie's Story" or via Training mode, competing against virtual poker opponents!
Here you can download the official version of Poker Arena for your Android devices.
Super Texas Holdem Poker Features:
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- Regular updates and improvements!
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Poker Arena from MY.COM is all you need for the winning!
Like us on https://www.facebook.com/mpokerarena
Český Poker
Snadno můžete přizvat své přátele a zahrát si s nimi, ať jste kdekoli. Ovládání je jednoduché a hra má spád.
Hru pro Vás připravuje profesionální a nadšený tým, k dispozici je uživatelská podpora. Designéři pro vás připravili přehledné uživatelské rozhraní s poutavou grafikou. Hra přináší řadu "vychytávek" a jedinečný systém herních bonusů, které si můžete pořídit za vyhrané žetony.
Chcete-li změřit síly s těmi nejlepšími, procvičit svou schopnost strategie a psychologie nebo si jen aktivně odpočinout při hře s přáteli, hra Český Poker je tou pravou volbou pro Vás. Neváhejte a pojďte to zkusit!
Co na vás čeká?
-Hra je zdarma a kromě mobilního telefonu nebo tabletu lze hrát také na Facebooku
-Možnost okamžitého zahájení hry s ostatními živými hráči
-Hra u jednotlivých stolů, vyřazovací turnaje velké šampionáty o ceny
-Hrajte se svými přáteli nebo se seznamte s ostatními hráči, můžete využít řadu speciálních funkcionalit, rozdávat dárky, dotvořit si svého avatara podle libosti
-Sledování žebříčku nejlepších hráčů a možnost propracovat se v hierarchii profíků až na Krále Pokeru!
Texas Poker.ID
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Sekarang download App ini, akan mendapat banyak chip gratis , alat dan hadiah.
Quick Hit Slots
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Quick Hit Slots is a play-for-fun casino intended for amusement only.
Slots 777 Casino by Dragonplay
Play the best free slot machines and free slot tournaments inspired by Las Vegas slot machines, Slots 777 Casino lets you win big jackpots anytime, anywhere for free! Join the Party now!
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Jackpot Madness Slots
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More Games from our parent company:
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Wild Bingo - FREE Bingo+Slots
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► Live Holdem Poker Pro - https://play.google.com/store/apps/details?id=com.dragonplay.liveholdempro
Dragonplay Poker Texas Hold'em
Play Dragonlay poker, Texas Hold'em Poker, for free against millions of real users worldwide. Register with your Facebook account or your email and join the Poker madness today. Played by more than 25,000,000 Android users. The masters of Poker play here!
Get Up to $500,000 free chips when opening an account for the first time!
Game features:
* Live Chat
* Fast Tables
* Shootout poker tournament mode
* Sit-n-Go poker tournament Mode
* Poker Ring Games
* Free daily Gold
* 200+ Virtual goods you can send people on tables
* Facebook connect for fast registration (optional)
* Dragonplay Poker Pro is a Poker game for entertainment uses only.
* The game does not offer an opportunity to win real money. Practice or success at social casino gaming does not imply future success at real money gambling.
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text:
6 Reviews
- Most Helpful
- Newest
- Highest Rating
This cake is outstanding - so moist and full of flavor. The instructions are dead-on (40 minutes was perfect). Also, be sure to use freshly squeezed lemons for the juice - makes all the difference. This recipe is perfect for couples (or singles) who like cakes but never make them because they can't eat them fast enough. Just the right size!
Wasn't a fan of this. The flavor was great, very lemony and not very sweet, but it was too dense. Felt like we had eaten rocks afterwards. I tried to chill it a bit, and that made it even worse. Good thing this recipe doesn't make much, we tossed the rest.
I too found this to be a dense cake and it didn't rise at all either. And I followed the recipe properly. But it was definitely a very moist and flavorful cake..nice and lemony. I had cut these into bars and they were good especially when they were warm. Thanks for sharing your recipe KitchenManiac.
Just the recipe I was looking for. The cake came out beautiful and moist. Thank you!
This was delicious!!! Lemony and moist with just the right balance of tart and sweet. It's so simple that it's dangerous too, lol. Served it with whipped cream which made it awesome, but it's good just by itself. Thanks KM!
WHOOHOOOO!!! This is some cake!! My oven temperature was off for about 15 mins so it didn't raise up as much as it would and it was a bit dense but I am giving it a 5-star review because I know if my oven didn't play up, it will be even better! Will leave it to chill overnight so that I can enjoy it even more tomorrow!


text: Cafe nomad is my go to place for some excellent Hummus with meat and pita. I love their hummus so much that on my last trip; I especially ordered for this the night before my wedding!! Their couscous is fresh and well balanced with vegetables and meat. Kebseh is a must have if you haven't tried it... read more


text:
Extraordinary Uses
Sure, yogurt's good for your body, but you'll never guess what else it can do! >>
Clever ways to prevent damage to your home's floors. >>
Wipe out awful smells with these household remedies. >>
Freshen your pail, freshen the room! >>
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Discover unusual ways you can use shoe bags to get more organized. >>
Out of window-cleaning formula? Try one of these solutions. >>
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Get a new -- or old -- baseball glove game-ready with these 4 tricks. >>
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Clean soap scum up quickly with these problem-solvers. >>
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Throughout a Warriors season that concluded in an NBA championship, restricted free agent forward Draymond Green stated a desire to see what kind of interest he would get from other teams on the o
Draymond Green reportedly broke off contract talks with the Warriors on Wednesday, about the same time he received a backhanded endorsement from former Warriors forward Stephen Jackson.
Tyson Chandler agreed to a four-year deal worth over $50 million with the Phoenix Suns on Wednesday.
The Warriors' first shot at retaining Draymond Green did not go as planned.
Despite a rocky first season as a Cavalier, Kevin Love announced he's going back to Cleveland, signing a five-year, $110 million contract extension.


text:
Schools Paying Kids To Show Up!
Some schools across the country are trying incentives to encourage kids to show up for school, like I-pods and cash.
Some schools across the country are trying incentives to encourage kids to show up for school, like I-pods and cash.
Coker College in South Carolina will require all incoming Freshman to participate in a Fitness Assessment test.
Now all super hero's than I have known have a spandex, maybe rubber suit, with a cape or a utility belt. This individual was a super hero that celebrated "Casual Friday" 7 days a week and evidently drank on the job while protecting the ladies
For every generation, there will most likely be something that we as parents can blame for the decline in school performance. My generation can blame the video game boom. (It all started with my Atari
According to a local Fox affiliate, a three-alarm fire on Sunday severely damaged Oregon's historic View Point Inn, better known to Twihards as the location of the famous 'Twilight' prom scene.
Reports say the fire was initially spotted by two 'Twilight' movie fans, who were there to catch a piece of movie history. Staff members then tried to put out the flames - which quickly "burned through the hotel's roof and gutted the top floor" - with a gardening hose, but were unsuccessful in their attempt.
Casey Anthony was sentenced to four years in jail Thursday for lying to investigators in charge of the search for her daughter, Caylee. However, Anthony will be set free on July 13 since she's served almost three years in jail while awaiting trial with a record of good behavior.
After deliberating for 10 hours and 40 minutes, a jury found Casey Anthony not guilty in the death of her two-year-old daughter, Caylee.
With all the talk of how broke the US government is, you might be surprised to learn there's over a billion one-dollar coins sitting unused in Federal Reserve vaults. And the US Mint is still cranking them out.
NPR's Planet Money and Investigations teams found that the coins are the wasteful byproducts of a failed congressional effort to get Americans to use them in everyday commerce.
A recent Gallup poll of 1,020 adults shows that, if Americans could only have one child, they'd rather have a boy than a girl
According to the poll, published Thursday, 40 percent said they'd want to have a boy, while 28 percent said they'd rather have a girl instead.
How rude!
That catch phrase from 'Full House' is now more relevant than ever, thanks to the results of the Civility in America survey.
The nuclear family is shrinking.
For the third-consecutive year, births in the US have decreased.
Robert Sayegh wanted to know why it was taking so long for his Atlantic Southeast Airlines flight from Detroit to Newark to get off the runway.
So he made a general inquiry as to the plane's grounded nature that admittedly contained R-rated language.


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Bachelor of Science in Nursing (BSN)
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Community Status Updates
Thanatosia → Jaxin
Wassup Jaxman! Hope you're well broseph :)Jun 13 2015 01:59 AM
Jaxinim real and still drunk and high as as ever! but how bout you movin to Cali1
Jun 15 2015 11:55 PM
Hi everyone. Does anyone feel like Dan's moisturizer feels thick or sticky? I like the ingredients but when it dries it feels like it just sits on my face and it feels uncomfortable to move.Jun 01 2015 07:14 PM
I am currently taking Spironolactone (75 mg per day) & using Benzoyl Peroxide facewash & Atralin gel. I'd like to connect ith others using this regimen & find out how their tretament is going. Tips & support are appreciated! :)Apr 04 2015 10:37 AM
been on the regime for about 4 to 5 months now. Results are decent. Skin condition has improved but still getting noticeable pimples (3-5) that's it's getting frustratingFeb 02 2015 10:59 PM
I broke out severely last two weeks after going on Bactrim once a day. However, went back to Bactrim twice a day and found a miracle blotting oil linen called Boscia. This could be my miracle cure. Pray for me!Dec 14 2014 03:44 PM
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Spring is coming — really! Break out of your cold weather beauty routine with these warmed up (and totally wearable) new looks.
more slideshows
5 Post-Sun Beauty Picks We Swear ByYou've had some fun—now it's time to refresh your hair
6 Healthy and Satisfying Summer Cocktails You'll Want To Make TonightWhip up a batch and enjoy all weekend long.
Girl Power! Life Lessons from the Littlest AthletesWe asked some of our favorite young sports stars what
5 Runway-Inspired Winter Makeup Trends
The Trend: A halo of pale purple, as seen at the Rochas spring show, is softer and easier to wear than a basic black smokey eye (and instead of enhancing dark circles, the cool color actually helps hide them). Run a chunky lavender eye crayon all around eyes at lash line, then smudge it with your pinkie finger for a diffused effect.
Your Tool: Avon Big Color Eye Pencil in Lavender Mist, $4.
KEYWORDS: Makeup Trends,runway,Spring Beauty


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Re: Extra coat of paint?
Expand Messages
- I didn't have to, but I guess it depends on how porous the wood is.
--- In firstname.lastname@example.com, "netbuz10101" <netbuz10101@...> wrote:
> I'm using Glidden polyurethane porch paint. It recommends using 2 coats. Should I use more?
> Thanks
> -David
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They feel bad, so they found you these other deals to make up for it.
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Genesis MechanicalRead MoreWe are a service company. our business is heating and Air Conditioning Installs, service and system replacements.We are certified by National Comfort Institute in air balancing.104 McCall LaneEasley, SC US
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Thursday, 28 Jul 2011
Aztech Powerline Experience Station Debuts at Challenger
Aztech announces the availability of an interactive powerline display station at the 24-hour Challenger Megastore in Funan DigitaLife Mall, Singapore.
QNAP Announces Availability of QMobile V1.1.1 for iOS
QNAP announced that QMobile v1.1.1 is available for download in Apple App Store.
ASUS to Release Android 3.2 Update to All Tablet Devices
ASUS will be providing the Google Android 3.2 updates to all its Eee Pad tablet devices.
DVI KVM ELR Extender Goes 100 Meters on a Single CAT-5 Cable
Gefen today announced that its DVI KVM ELR Extender (EXT-DVIKVM-ELR) is now shipping.
Google Maps 5.8 for Android Adds Photo Upload Feature
Google Maps adds more features to enhance its usability, such as photo uploads and allowing you to add new places with your Android device when you're on the move.
Lenovo Launches IdeaPad and ThinkPad Tablets
Lenovo announces the first two devices in its tablet family - the sleek and stylish IdeaPad Tablet K1 for consumers and the robust ThinkPad Tablet for business customers.
Prepare for Electrifying Audio with the Razer Electra
Designed to deliver powerful bass depth and crisp clear soundstages in a comfortable and versatile package, the Razer Electra takes your thumping music beats and exciting game audio to the streets.
HIS Delivers its 6770 IceQ X Turbo
The HIS 6770 IceQ X Turbo is loaded with a core speed of 850MHz and a memory speed of 4800MHz, delivering high definition gaming frame rates.
Exploding Batteries to be Thing of Past
Exploding Lithium-Ion batteries may soon become a thing of the past. Researchers from Layden Energy have come up with a more heat and corrosion resistant Lithium-Imide battery.
Learn to Play the Piano the iPad Way
The Piano Apprentice is a lightweight 25-note keyboard with built-in stereo speakers and even has videos of acclaimed piano instructor Scott Houston's hands teaching you how to play!


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Play Video
Dog in zero gravity
Posted by S_M_N on Dec. 19, 2006
Break celebrates 4th of July the American Way: by laying the smack down on ...
With the 4th of July around the corner, we celebrate the most kick-ass USA ...
Dude, are you drunk AND high? Or are you just being PRANKED?!
Posted by S_M_N on Dec. 19, 2006


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"It's hassle free and user friendly. Both check-in options are simple, fast and get families on the way to their vacation quicker."
Related quotes
"It seems the distributors have made a simple calculation, and decided they do not need the hassle of political demonstrations outside their cinemas."
"I advise you to say your dream is possible and then overcome all inconveniences, ignore all the hassles and take a running leap through the hoop, even if it is in flames."
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"I wish there wasn't a ban because it's such a hassle. A regular smoker wants a cigarette before bed, and at other times when it's a pain in the ass to drop what you're doing to go outside."
"IrSimple instantly connects enabled devices, eliminating the hassles found in other wireless technologies. With over 200 million IrDA-enabled mobile phones sold in 2004, IrSimple is being launched from an extremely solid base."


text:
The Russian Doll of Hinduism in Ten Sanskrit Terms
What Is Hinduism?
What Is Hinduism?
What is Hinduism? To many in the West it's a bizarre and alien religion teeming with multi-armed gods and irrational beliefs, crawling with holy cows and complex rituals; archaic, gaudy, and defined by bizarre and very un-Western traditions such as primitive idol worship and the despicable caste system. A big, pagan city whose winding alleyways go through districts so foreign to our own culture one might easily get confused and hopelessly lost, so better stay away. As a result Hindism, more perhaps than any other religion, is often reduced to cliché, prejudice, and outright fallacy.
That's why I prefer the Russian Doll image of Hinduism to the Big City, the outer and more conspicuous, sometimes bizarre form of each separate doll peeling away to gradually lead to an inner, deeper, single Truth common to each one. Behind the seemingly bizarre outer appearance of Hinduism lies a quieter, less conspicuous, more abstract core, a philosophical mind-set not usually visible or comprehensible at first glance, and inaccessible through our everyday language. To get beneath the skin of these deeper concepts it's a good idea to learn a few Sanskrit terms: words for which there are no English translations. I've chosen ten which, it seems to me, are essential for a basic understanding of the essence of Hinduism.
Written by Sharon Maas
5 Things You Didn't Know About PridePride is the sin that brought down Heaven's first worship leader, Lucifer. Pride...
Stranded for 21 Days on a Beach, 'Miracle Child'...Martunis was playing soccer on a beach when a deadly tsunami struck the coast...
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5 Things You Didn't Know About LustThe sin of lust is an intense desire that controls behavior. Also known as lechery,...
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Military Academy Advisory Board visit to the Unit
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Working on a D&D map for a pal and created this layer to create a background texture for the work. See the full piece here: http://www.flickr.com/photos/hellaboss/8292486255/in/photostream
oh! here it is in use: http://www.flickr.com/photos/hellaboss/8293539992/in/photostream/
More Mathew Hoy
keyboard shortcuts: ← previous shot → next shot L or F like Z toggle zoom


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James Comer has conceded the governor's race in Kentucky, ending a tumultuous Republican primary and handing the nomination to Louisville businessman Matt Bevin.
State election officials say there are no changes to the vote totals from Kentucky's Republican primary for governor.
Kentucky Republicans waiting to see U.S. Sen. Mitch McConnell put his arm around his political nemesis Matt Bevin will have to wait a little longer.
Matt Bevin has done laps around Kentucky in a messy black suburban, searching for his big political break.
Kentucky's Republican primary for governor has turned negative with the airing of attack ads by an outside group supporting Hal Heiner's campaign.
Former Republican Senate challenger Matt Bevin said it's likely he'll run for governor in 2015.
Senate Republican Leader Mitch McConnell defeated primary challenger Matt Bevin in the primary election Tuesday. But Bevin says he isn't ready to back the senator.


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Restart for FF is a must-have Rated 5 out of 5 stars
I have always wanted the ability to restart Firefox. As it is, the choice is to either reboot or close my browser. Rebooting is time-consuming and in general a pain in the … well, you know - but you can keep your environment. Close the browser and you lose all your tabs. A lifesaver.


text:
Forum - View topicWhat does Sailor Moon mean to you? Audience Favorites - Final Round
Goto page 1, 2, 3 Next
Note: this is the discussion thread for this article
|View previous topic :: View next topic
ANN Publisher & CEO
Posts: 8730
Location: Do not message me for support.
I'll put announcements and answers to questions in this post so people can see them. No TLDR excuses.
These are just the audience favorites.
The Grand, First, Second and "Most Original" prize winners are not listed here. You'll find out who they are over the next couple days.
Don't worry about it. Your vote was counted. The page that the survey redirects to after voting hadn't been posted. I've fixed it, but there's no need for you to vote again. (If you return to the survey you'll see that your vote is saved, although you can change your choice...)
If you want to see the after vote page, here it is: animenewsnetwork.com/contest/2014-07-14/what-does-sailor-moon-mean-to-you/.76663
Voting will last several days. But I will close it later this week without prior warning. The Audience Favorite winner will be announced towards the end of the week.
Last edited by Tempest on Mon Jul 14, 2014 5:17 pm; edited 5 times in total
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ANN Publisher & CEO
Posts: 8730
Location: Do not message me for support.
I had a really hard time choosing my favorite from this list. I really feel bad for Char and the team at Viz who had to look through all the finalists to pick the grand prize (and other prize) winners.
Out of 36 entries, there's easily 10 that I would have happily voted for.
In the end, my choice was for meeks. It was one of my favorite two pieces of artwork in the final round, and I like how the fan-art was relevant to the story.
In terms of pure artistic merit though, I think Brianna Angelakis' is one of the two best in the entire contest.
Last edited by Tempest on Mon Jul 14, 2014 4:21 pm; edited 1 time in total
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Posts: 1131
Aww poop, I didn't make it, neither did the person I wish would have won...
Or were these just the one picked for audience favorite only? :0
Maybe I misunderstood.
[trying not to make a repeat post]
I literally had a hard time choosing my favorite as well... @__@;
And I know two people in this list and my heart goes for Princess Mentality Cosplay because I can relate to her in so many ways regarding PoC cosplay.
But then, Bree and Sable point also gave me some feels here.
This is really hard.
Last edited by tygerchickchibi on Mon Jul 14, 2014 4:29 pm; edited 2 times in total
|Back to top
Emma Iveli
Posts: 437
Location: San Francisco CA
I didn't get in either... But one of the people I wanted to see get the prize the most is one of the finalists which is good (It's Evan by the way...)
Looks like the rallying my fans was all for naught (unless I win one of the other prizes, which I doubt). I guess none of my fans were registered here... Oh well...
On the bright side working on one of the stories during the rally gave me a big dose inspiration for it... before then the plot was aimless, now it has a real plot-line!
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Posts: 3
Location: United States
[Post Removed]
Last edited by MiharuTan on Thu Oct 09, 2014 8:39 am; edited 2 times in total
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Posts: 1131
I find it interesting that a majority of these people, however have fan pages, lol.
Not like the Viz Staff would know, but I know a few people who are posted are popular on the interwebs.
|Back to top
Sailor Star Dust
Posts: 153
Location: US and A
Hoping I made it into one of the other categories. Lots of solid choices for the Audience Favorite category.
EDIT: Bah, I'm also getting a 404 with voting.
Edit (true^2): Looks like the voting 404's been fixed
Last edited by Sailor Star Dust on Mon Jul 14, 2014 5:06 pm; edited 1 time in total
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Posts: 1131
Oh, I don't see a deadline for voting here. I do see announcements for the winners starting tomorrow, so does this mean we only have one day to vote?
Did I also overlook it?
|Back to top
Posts: 58
|I got a 404 with the voting as well. But if I can eventually make it go through, I would definitely vote for that cute little comic ^^
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Posts: 11
|Yeah, I'm getting the 404 error too... : ( Anyone know what's going on with that?
|Back to top
Sailor Star Dust
Posts: 153
Location: US and A
|It's been fixed.
|Back to top
Posts: 11
Oh, great! Thanks for telling me, : )
|Back to top
Posts: 7
I got into contact with my favorite finalist (found her on twitter on accident actually lol) (so glad she made it!!) and I can assure you that she isn't popular on the internet and most people don't know who she is so I think a lot of this voting was done very fairly.
I sure hope she wins! It's the Lauren Ashley one.
Brianna's artwork is breathtaking. Based on art, I adore hers.
Tempest you are right, some of these are simply so amazing. I wish there were more winners in the contest.
|Back to top
Posts: 4
Yeah...and I've seen a few cases of some begging/pleading for votes from their "fans" as well.
But. I have faith the fans will dole out some moon justice and vote for the entries that really deserve it because of what they are, and not just who's in them.
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Posts: 36
I actually purposely checked to make sure i didn't vote for someone who did this on a fanpage i follow on facebook. i left her a comment saying it wasnt fair and tried to be nice to her about the whole thing (some other people also commented to her) she rly didn't seem to care though but i hope people actually read the stories for their merit and not just vote for people they may have some contact with, with the few finalist on this page now i think people will vote fairly now because its easy to read about 20 or so entries.
In response to tempest, i think its cool u ended up liking Brianna Angelakis because i remember she was the last entry added and because of a forum post! I liked hers too, although the person i would have picked for 'most creative' is still in the running for audience favorite so ill be curious as to who won that prize. =)
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Anime Expo 2015 News Roundup: Day One
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Showing Suppliers 1 - 10 of 10
Grainger Industrial Supply (21 Products)
Business Type: Distributor
Description: Grainger helps customers save time and money by providing them the right products to keep their facilities up and running. Grainger's customers are 2.0 million businesses and institutions in 157 countries. While each customer has a unique facility to operate and a different problem to solve, our... (more)
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Address: 4314 Will Rogers Pkwy. Branch 568, Oklahoma City, OK
Address: 10707 E. Pine St. Branch 864, Tulsa, OK
Capitol Lift Truck, Inc.
Address: 2421 SW 14th, Oklahoma City, OK
Business Type: Distributor, Service
Holly Equipment
Address: 8180 East 46th Street, Tulsa, OK
Business Type: Distributor
Keathley Handling Solutions, Inc.
Address: 1547 SE 25th Street, Oklahoma City, OK
Business Type: Distributor, Service
LPM Forklift Sales and Service, Inc.
Address: 7700 NW 39th Expressway, Bethany, OK
Business Type: Distributor
Medley Material Handling
Address: 4201 Will Rogers Parkway, Oklahoma City, OK
Business Type: Distributor
Preferred Material Handling, Inc.
Address: 813 SE 84th St., Oklahoma City, OK
Business Type: Distributor, Service
Sooner Lift, Inc.
Address: 3401 S. Purdue St., Oklahoma City, OK
Business Type: Distributor, Service
Waldon Manufacturing, LLC
Address: 201 W. Oklahoma Ave., Fairview, OK
Business Type: Manufacturer


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No doubt, this is the place I am going to visit when I am back in Amsterdam. Best room, big and comfortable, best location: the jordaan is a wonderful area quiet to stay and nearby the core of the entertainment and the museums. Bike rental a few metres far away(highly advised too! ). So, best place! Jackie and ziggy are the best hosts ever!
- Official Description (provided by the hotel):
- Jackie O's B & B consits of only one room for 2 and is located on the first floor (up one stair)of a listed building on the quiet Bloemgracht, the bustling heart of the Jordaan district. The room with a fantastic view of the canal has a separate entrance, a fully equipped kitchenette and a private bathroom. Upon request, the fridge is stocked with all the ingredients for a hearty breakfast and a morning fresh bread and fresh orange juice to put the door. LCD TV, free WiFi and sound system (including I-Pod and I-phone) are available At 5 minutes walking distance you will find the famous Anne Frank House, Wester, the shopping streets of the 9, tram and bus station and supermarket. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Expedia, Travelocity and Hotels.com so you can book your Jackie O Bed & Breakfast reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.