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Sonja M. Thomas
Office: Miller Library 256 [ campus map ]
Box 8800
Phone: 207-859-4722
Fax: 207-859-4425
E-mail: firstname.lastname@example.com
Mailing Address:
8800 Mayflower Hill
Waterville, Maine 04901-8888
8800 Mayflower Hill
Waterville, Maine 04901-8888
Areas of Expertise
- South Asian Feminisms
- Transnational Feminist Theory
- Critical Race Feminisms
- Human Rights
- Syrian Christianity in South India
- Tap Dance
Other Courses Taught
|Course Title
|Gender and Politicized Religion
|Critical Race Feminisms and Tap Dance
WGSS homepage
Critical Race Feminisms and Tap Dance video link
WGSS homepage
The directory information is for individual use only, it may not be retransmitted or published for any reason. It is not to be used for mass solicitations by e-mail, mail, phone or other means. Sale or other distribution of this document is prohibited by College policy.


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x 06
x 06
Sep 29, 2006 3:40PM PST
that was niiiice i want an xbox 360 even more now =)
Comments (1)
oooPosted: Oct 07, 2006 12:00AM PST by XSniper1126
Oh yea, I can hardly wait for all those games!
Check out my blog to see which ones. ^_^

subset: commoncrawl


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The video points out locations of different accents in the British Isles. It is a short video, but is quite a tour of the numerous accents you would find on that relatively small geographic area.
A Tour of the British Isles in Accents [video]
I Feel You Bro: Man Staged Home Burglary To Avoid Work
People will do crazy things to avoid going to work on a Monday, and we can totally understand and sympathize with this man's predicament. Monday morning this week, at 7:25 a.m., Florida resident Dwayne A. Yeager called the Hillsborough County Sheriff's Office to inform them of a burglary at his house.
Blood Bath Shower Curtain
Too many movies to be recounted have utilized the old murder in the shower trick where the viewer simply sees the outline of the blood stained hand and its subsequent drop. This shower curtain will create the same effect for your bathroom, minus the murder and real blood. It would work beautifully as a gag; one your guests would love. Costs $10.70.
English Is Crazy
Damn English, you cray cray. The video takes a look at several written words and their pronunciation, showing how spoken English can be oh so different than written words.
A Girl Named Elastika
One thing I can tell you about Elastika, that girl is resourceful. Also, she has brought office supplies to their most useful ever since they were invented. The stop motion animation is the work of French filmmaker Guillaume Blanchet.
Umbrella With Coffee Cup Holder
Morella umbrella attachment makes pretty good sense. Raining doesn't mean I have to forego my coffee, or get both hands full. Morella adds cup holders to the umbrella so you could set your coffee safely and use the free hand to use the phone, or just say hello to someone.
Amazon Fire TV
Amazon has announced its own streaming media player, the Amazon Fire TV. Capable of HD video streaming, the device comes as a box that attaches to your HDTV, and can stream content from services like Netflix, Prime Instant Video, Hulu Plus, and WatchESPN, along with several others.
Classic Japanese Katana Sword With a Contemporary Design
Aikuchi is a katana made with traditional Japanese skill in collaboration with Australian designer Marc Newson. The katana does not include a "lower guard" in its design, so in the traditional sense, it is not a weapon but something more like a good luck charm.
Toilet Paper Embossed With 24 Carat Gold
It's yellow so it is a match, unless you had some iron-rich food for dinner. Ideally, we would suggest mixing up the gold embossed toilet paper with the gold pooping pill. The toilet paper is gilded with 24 karat gold, and has a few design options to choose your preference. Designs are custom made by Fritz Loibl for the German company Tissue Design. Each roll is priced at $246.
Skull Candle Bleeds Through Its Eyes
The season of scary is never out of season, especially when you can get something as simple as a candle to do bidding of the evil overlords. Once you light the skull candle, red wax flows out through the skull's eyes giving an appearance of blood. Not to mention, the hollow eyes of the skull show a raging inferno within. Costs £20 ($33).


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Free virus with the purchase of a Maxtor Basics Personal Storage 3200. See the internet for details.
Originally Posted by metarinka
how could you have a virus on a HDD, don't you have to format and partition it before it's even usable?
Originally Posted by news article
free 60-day trail of it's antivirus
Originally Posted by thecrownles
I'd be interested in seeing how this happened.
Originally Posted by Pokekevin
Wow how did a virus get on the hard drive....sucks for people playing wow
Hex Gear R40 Preview Build
25th June 2015
SilverStone Kublai KL05 Review
25th June 2015
AMD Radeon R9 Fury X Review
24th June 2015


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Pervasive beggary is shaming us
We have poverty eradication programmes aplenty but none by way of eliminating beggary. Thus, we get to hear of the declining numbers of people below the poverty line being claimed as poverty alleviation successes.Continue reading...
Violation of professional ethics
A report published in this newspaper yesterday reveals an alarmingly high number of caesarean deliveries performed in private hospitals.Continue reading...
Dr Fahmida Khatun
Moving lower middle income status forward
For Bangladesh, moving ahead also means that it has to diversify its exports and move towards high value products.
Smruti S. Pattanaik
Mahinda Rajapakse Bounces Back
After months of negotiation and show of strength, former President Mahinda Rajapakse was finally given a ticket to contest by the Sri Lanka Freedom Party (SLFP) which is part of the United People's Freedom Alliance (UPFA), a conglomerate of around sixteen parties.
Sushmita S. Preetha
Imagine a life of never fitting in, of constant ridicules and derisions, of being shunned by your own family, of being denied jobs and a chance at a "comfortable" life, of being harassed and assaulted, often sexually, because of who you are.
Mohammed Muniruzzaman
The bright future of renewable energy
Even though smart technologies and new methods of harvesting energy are being added regularly, the solar panel will be with us for some time.
Lam-ya Mostaque
For citizens of Bangladesh, the news of fellow countrymen dying some horrible death is not new. Reports of gruesome murders, torture,
Mahmood Hasan
So near, yet so far
When the standoff over Iran's Nuclear Deal seemed to be coming to an end, new sticky issues emerged. The P5+1 (five UNSC permanent
Emran Mahfuj
"Bangalis are trying to get ahead by forgetting the past"
Born in 1939 in Bardhaman, West Bengal, Hasan Azizul Huq is one of the greatest figures in Bangla literature. He has written short
Levy heavy fines on cigarettes
Smokers not only destroy their health but also those of innocent non-smokers, by forcing them to inhale in an environment of tobacco smoke.Continue reading...
Stop Rampal power plant project
On June 29, while speaking in the parliament, PM criticised those who opposed the construction of the coal based power plant near the Sundarbans.Continue reading...
These hooligans are protected by their politically affiliated family members; Rony must face justice like any other citizen.Continue reading...
Letters to the Editor
Congratulations to Bangladesh cricket team for a decisive series win against India. I believe the four pacer combination is perfect forContinue reading...
"Bangalis are trying to get ahead by forgetting the past"
Born in 1939 in Bardhaman, West Bengal, Hasan Azizul Huq is one of the greatest figures in Bangla literature. He has written short
How to get a break from the six percent growth trap
The recently announced national budget has sparked considerable debate among economists, business leaders and the general public.
The Story of the Dirty Black Road
Contrary to all that can be defined as the reality around me, I do believe in miracles. Call me naïve, delusional or just plain silly, but when you see a really grotesque problem actually being
Aftermath of the 1965 War
The Kashmiris have come to develop a different thinking. They do not want either India or Pakistan to be the arbiter. They themselves want to decide what is suited to their genius.


text: United States United States Mariya Karimjee on Oct 11, 2011 @ 1:53 PMOct 11, 2011 @ 1:53 PM PublishedChris Christie will endorse Mitt Romney for presidentNew Jersey Governor Chris Christie speaks to a full house at a Reform Agenda Town Hall meeting at the New Jersey Manufacturers Company facility in Hammonton, New Jersey on March 29, 2011.New Jersey Governor, Chris Christie will endorse Republican presidential candidate Mitt Romney on Tuesday, Fox News reports.His formal endorsement will be made in Hanover, N.H. before the Republican presidential debate that will be held Tuesday night. The announcement comes a exactly one week after Christie's announcement last week that he will not run for president. Christie, who had repeatedly said that he wouldn't run for president, admitted last week that he had been considering a late entrance into the race, because of the encouragement he had received from others.However, Christie explained that he had too much to take care of in his home state. More from GlobalPost: Chris Christie not running for president.


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Month: April 2013
Islam And Immigration
Who is our enemy? President Barack Obama is convinced it is Americans that simply want to exercise their Constitutional right to bear arms. At the same time, the President refuses to condemn Muslims both foreign and domestic — religious fanatics, like the Boston bombers, who are part of a global jihad and have declared America the "Great Satan."
For all his education, with all of the intelligence services at his fingertips and with nearly 12 years of attacks on American soil, our President remains willfully blind of what must be done to protect America when it comes to Islam and immigration. Instead, his focus is on guns. This was on display when the President railed the Senate for rejecting his gun-control legislation.
"I see this as just round one," said the President, surrounded by relatives of the Newtown, Conn., victims as well as former Congresswoman Gabrielle Giffords, who was shot in Tucson, Ariz.
Obama said Senators are fearful that "the gun lobby would spend a lot of money," accusing them of opposing the Second Amendment's right to bear arms.
On Friday, shortly after the capture of the surviving Boston Marathon bomber, Obama went on television to tell Americans not to be quick to judge any one group of people. Translation: Don't blame Muslims.
The President can tell that to Dzhokhar Tsarnaev. The surviving suspect in the Boston bombings posted links to Islamic websites calling for Chechnya's independence.
Tsarnaev proclaimed his "world view" as Islam. Other posts from him include: "Salamworld, my religion is Islam" and "There is no God but Allah, let that ring out in our hearts."
His dead brother, Tamerlan, said once said, "I don't have a single American friend. I don't understand them." He said that despite the fact that he trained almost daily to become a champion amateur boxer while living in Boston.
To this day, some of the best friends I have were people I met at the boxing gym. It seems impossible to me to work so hard for a boxing team with coaches and other fighters and not make friends. Then again, I boxed while in Spokane, Wash., when I was an immigrant from Canada — an immigrant who shared the same Christian and democratic values as my coaches and teammates.
It is becoming increasingly apparent that the Boston bombers rejected, rather than embraced, American values so much so that they sought to terrorize the Nation by killing and crippling women and children. I don't see this type of behavior in immigrants to America or Canada who are Latino, Asian or Western European.
"Islam is not just a religion," writes Mark Steyn in his book, America Alone: The End of the World as we know It. "Those lefties who bemoan what America is doing to provoke 'the Muslim world' would go bananas if any Western politician started referring to 'the Christian world.'… So it's not merely that there's a global jihad lurking within this religion, but that the religion itself is a political project — in a way that modern Christianity, Judaism, Hinduism and Buddhism are not."
Let me share something that happened at the Calgary airport shortly before my family was boarding a flight. My daughter's friend is a petite and shy Lebanese young lady. We have known her for more than a decade.
As we headed for the gate, I noticed four women in full Islamic dress walking toward us. As I was lagging behind, I saw our young friend approach them and be rudely rebuffed. I then saw my wife hug her, and I noticed the girl was in tears. I wanted to know why. My wife told me that the women were her aunts and that because she had adopted a Western lifestyle (in part, probably because she was with infidels such as us) she was shunned.
Why Won't Obama Suspend Islamic Immigration?
It is clear that the President is determined to neither limit nor — Allah forbid — restrict immigration of Muslims into the United States. There is no reason why the United States cannot implement serious restrictions on any or all peoples wanting to reside in America. Switzerland has been doing it for decades.
As Obama continues to respond to the Sandy Hook tragedy with gun legislation, you can bet he will resist any calls for immigration restrictions — especially if Muslims are the target. The only good news is that Obama may have a fight on his hands with the Senate because the Boston bombers came from predominantly Muslim Chechnya, a Russian-occupied nation in the Russian Caucasus.
Senator Chuck Grassley, R-Iowa, said at a hearing on immigration reform last Friday that it would be prudent to review the process.
Given the events of this week, it's important for us to understand the gaps and loopholes in our immigration system.
How can individuals evade authority and plan such attacks on our soil?
Other leaders are grasping a fundamental truth about America's real enemies. Last week, Representative Peter King (R-N.Y.), a member of the House Committee on Homeland Security, said the Federal government needs to take its blinders off when it comes to immigration:
I do believe that whether it's Chechnya or whether it's really any countries from areas where there is fighting going on–particularly terrorist fighting–that we have to be extra careful, extra scrupulous. That would include, to me, Yemen, Saudi Arabia, Somalia [and] obviously …. somebody of a Chechnyan background. All of that, to me, we can't afford to be politically correct and say that somebody coming from a country where there's a Muslim war going on is the same as somebody … from Switzerland, for instance. There's a difference.
Islam's Growing Foothold
Pew Forum reports:
In the United States… population projections show the number of Muslims more than doubling over the next two decades, rising from 2.6 million in 2010 to 6.2 million in 2030, in large part because of immigration and higher-than-average fertility among Muslims.
In 2011, the National Post quoted Tarek Fatah, an outspoken secular Muslim leader living in Canada: "[W]hat is different from other immigrant groups is there is a subgroup among Muslims, I call Islamists, who come [to Canada] with the intention of destroying the social fabric of the country."
As for the majority of Islamic immigrants, most refuse to become part of America's melting pot. They cling to their unforgiving religion and medieval traditions. Among them are radicals who preach jihad against America. An even smaller minority will accept this call to arms, people like the alleged killer at Fort Hood, Texas, or the terrorists in Boston.
In Canada on Monday, the Royal Canadian Mounted Police arrested two apparent Islamic terrorists who were allegedly planning to derail a passenger train and kill Canadians.
I can already hear the outcry from liberals who will label me a racist. But, hey, I didn't start this fight; the followers of Muhammad did that a decade before I was even born when the United States threw its economic and political might behind Israel.
In his best-seller The Looming Tower: Al-Qaeda and the Road to 9/11, Pulitzer Prize winner Lawrence Wright traced Islamic hatred of Westerners back to one man, an Egyptian dissident named Sayyid Qutb.
Qutb was an Egyptian author, educator and Islamist theorist who immigrated to the United States in 1948. (He later returned to Egypt.) He has been called "the man who inspired [Osama] bin Laden," and it is not hard to see why he earned that reputation after you read his philosophy on infidels.
Wright wrote:
He also brought home a new and abiding anger about race. "The white man in Europe or America is our number-one enemy," he declared. "The white man crushes us underfoot while we teach our children about his civilization…"
It may be that only two in 10,000 Muslims have bad intentions against the United States; but as the suspected Boston-bombing brothers from Chechnya proved last week, that is two too many.
Yours in good times and bad,
–John Myers
Editor, Myers' Energy & Gold Report
House Votes To Legitimize More Government Computer Snooping
No amount of online spying is too much, said the criminal elected class in the House of Representatives, as it passed the Cyber Intelligence Sharing and (non)Protection Act (CISPA) yesterday over hollow veto threats by the Administration of President Barack Obama.
The bill will give the government access to online data — including financial data — from private computer networks. A proposal that would have prohibited the military from collecting data directly from industry was blocked from floor debates by Republicans. A compromise measure was passed that ensures companies must first go through the Department of Homeland Security before turning information over the military.
Privacy groups object to the bill because they said it would give the National Security Agency "a front-row seat in analyzing data from private computer networks." The Associated Press reports that the bill doesn't address NSA specifically, but "it's presumed that the military intelligence agency would have a central role in the data-sharing because of its technical expertise in tracking foreign-based hackers."
Senator Jay Rockefeller (D-W.Va.), who once lamented that the Internet had been created and longed to return to the days of pencil and paper, will take the lead in pushing CISPA through the Senate.
The proposal that puts DHS in charge of disseminating the information between corporations and the military was supposed to be comforting. But considering the DHS's record regarding electronic privacy, it's no comfort at all. Recall that for years DHS claimed the naked body scans taken by backscatter radiation emitters at airports were not stored, and the machines were not capable of storing images. Finally, after lawsuits filed by the Electronic Privacy Information Center made their way through the courts, it was revealed that DHS did indeed store the images and that Transportation Security Administration agents used them for all sorts of nefarious purposes.
The Administration's veto threats ring hollow because it has yet to find a liberty-reducing law it could oppose (see the National Defense Authorization Act). But we should be thankful, because our safety is of foremost concern among the criminal elected class.
Regulate The Environmental Protection Agency If You're Really 'Green'
Earth Day was celebrated throughout the Nation earlier this week with the routine tree-planting ceremonies, litter-cleaning outings and school lesson plans based on environmental stewardship. And, of course, there was the requisite alarmist shrieking from those Americans who believe the Presidential Administration's hyped up warnings that the United States is on the verge of becoming a 3.8 million square mile garbage dumb — because of the sequester, of course.
Aptly timed with regard to the White House's policy of making even the smallest cuts related to sequester as visible as possible, the Environmental Protection Agency began implementing furloughs that will affect its nearly 17,000 employees on April 21. With Earth Day on the brain, supporters of the agency's continual red tape throttling of American industry took to the Internet in droves early this week to lament that cutbacks mean impending environmental doom for the United States.
The EPA does perform some rudimentary functions in the name of environment protection that all Americans should appreciate. After all, we all require clean water; and no one wants to breathe smog-ridden air or suffer health problems in the name of industrial profits.
But to suggest that the EPA has no room to make budget cuts if Americans aren't willing to live in an industrial cesspool of hazardous waste is to suggest that the EPA could not have saved some money and continued reasonable environmental protection endeavors by cutting these items from last year's budget:
- A $141,450 grant under the Clean Air Act to fund a Chinese study on pig manure.
- A $1.2 million gift to the United Nations for the "promotion" of clean fuels throughout the world.
- A $67,926 poster contest at Syracuse University that had fewer than 10 entries.
- Twenty EPA conferences costing an average of $182,847 for a total conference bill of $3.7 million.
The EPA may be dealing with some budget woes; but there is plenty of evidence that throttling down some of its more burdening regulations, especially those that heavily penalize coal-powered energy producers in the name of promoting yet-to-succeed green energy initiatives, could embolden the economy as a whole, thus increasing government revenues down the road.
A study conducted last year by the National Economic Research Associates examined the impact of seven EPA regulations on coal-fueled power plants. Researchers found that those regulations will ultimately be responsible for up to 887,000 yearly job losses in that industry alone in coming years. The study also indicated that compliance costs for the electric sector was around $16.7 billion per year.
There is currently a legislative movement to require the EPA to report the projected financial burden of new environmental regulation.
The examples of government wasteful spending and the costs of regulatory actions could go on ad infinitum — but the bottom line for many conservatives is that the EPA should back off on its assaults against coal power and industry until environmentalists have a better plan. Government-subsidized green-energy disasters like Solyndra provide evidence that fossil fuels are here to stay for at least a while longer.
Environmentalists commonly argue that the United States must be at the forefront of environmental protection, a shining example of a clean industrial nation for the entire world to see. But, if overbearing regulation chases industry from the Nation and puts more Americans on the welfare rolls, does it make sense that countries that have just recently pulled themselves from the pits of poverty with the help of industry (burdened by far less regulation than their American counterparts) will follow suit? It seems more likely to many observers that international interests will jump at the opportunity to welcome more industry and lure manufacturers with the promise of regulation-lite operating environments.
Unless the EPA can figure out a way to keep wind and water from moving fluidly across geographic borders, many would argue that they ought to lighten up on American industry and do their best to slowly coax those lesser-of-evil polluters to the side of clean, green environmental manufacturing with profit motives.
Disgraced Rangel Sues To Overturn House Censure From 2010
Comic-relief Representative Charles Rangel (D-N.Y.), who last month told Americans that assault weapons are killing "millions of kids" in the United States, is suing seven lawmakers — including House Speaker John Boehner (R-Ohio) — to have his House Censure from 2010 overturned.
You may remember that clownfest from three years ago. The House smacked Rangel hard, voting 333-79 in favor of the rebuke for Rangel's admitted involvement in:
- Dodging Federal income tax on money he made from rental property — for 17 years.
- Filing purposely misleading documents with the Internal Revenue Service.
- "Failing" to report $3 million in business dealings from 2002 to 2006.
- Omitting the 2004 sale of a Harlem residence from his tax filing.
- Lowballing his assets' worth — by $780,000 — when reporting to the IRS in 2007.
- Using Congressional letterhead to solicit donations for a monument to himself — literally — and receiving the money from companies and charities that had matters before Congress' Ways and Means Committee, which Rangel chaired at the time.
- Operating a campaign office out of a Harlem apartment he instead claimed as his residence.
A censure is a bad thing (in fact, the only worse thing Congress can do to one of their own is to expel him altogether), and it involves ceremony and public humiliation. Rangel had to stand in the well of the House while then-Speaker Nancy Pelosi (D-Calif.) read a House resolution telling him what a bad guy he'd been. It was great public theater.
But, in practical terms, censure is dreaded more for what it can do to a political career than for any legal teeth it has. In Rangel's case, censure didn't affect his career, other than his having to step down from his chairmanship of the Ways and Means Committee. Rangel's Harlem constituents have re-elected him consecutively and, usually, overwhelmingly to additional terms ever since he first took office in 1971, and they did it again in 2012.
Now 82 years old, Rangel, a founding member of the Congressional Black Caucus, isn't content with immunity from prosecution and sailing to re-election yet again. Five months into his new Congressional term, he's going after history itself. He wants the censure gone.
He's not proclaiming his innocence, though. Like any good lawyer, the former Federal attorney is trying to get off on a technicality. Rangel claims the House Ethics Committee knowingly deceived the full body by not revealing that it may not have followed procedural rules as it conducted the investigation.
Michelle Malkin noted Monday that Rangel might be courting disaster by asking for an examination of how the Ethics Committee did its investigative work. It's possible, after all, it didn't catch every crime and malfeasance the first time around.
No Place For Liberty In The Progressives' Timid New World
The Founders' vision of the United States as a beacon of liberty for the rest of the world grew largely from their desire to ensure that the Nation never resembled that from which they were forced to fight a bloody war to free themselves. The law of the land, in its original construct, was designed to protect personal freedom, privacy and the right to self-preservation against the malicious intent of both agents of the state and free-actors with equal vigor.
But, for busybodies and statists hell-bent on total control, the modern world is too different a place for Americans to value the historic advice — and legislation — of the Nation's Founding Fathers. And every tragedy or event that has the potential to affront the hearts of Americans with the least bit of unease represents a new chance for the liberty-averse to make their case for less Constitutional consideration.
If you don't believe the preceding statements coming from an average American peon who values his own naturally ordained and Constitutionally guaranteed rights, take it straight from the horse's mouth.
Speaking in reference to the Boston Marathon bombing that occurred last week, Mayor Michael Bloomberg — who has gone out of his way to make New York City as Constitutionally bereft as possible — had this to say: "The people who are worried about privacy have a legitimate worry. But we live in a complex world where you're going to have to have a level of security greater than you did back in the olden days, if you will. And our laws and our interpretation of the Constitution, I think, have to change."
Bloomberg said later in his remarks: "It really says something bad about us that we have to do it. But our obligation first and foremost is to keep our kids safe in the schools; first and foremost, to keep you safe if you go to a sporting event; first and foremost is to keep you safe if you walk down the streets or go into our parks. We cannot let the terrorists put us in a situation where we can't do those things. And the ways to do that is to provide what we think is an appropriate level of protection."
Just outside of Bloomberg's city in New York Harbor stands a world-famous neoclassical sculpture given to the people of the United States by France in 1886. Originally named La Liberté éclairant le monde, or Liberty Enlightening the World, the Statue of Liberty is representative of the Founders' vision of an America known worldwide as a beacon of liberty. For more than a century, the colossal representation of the Roman goddess Libertas has watched over the city with her ever burning torch in one arm and tubula ansata, representative of the rule of law, in the other.
In the stairwell of Lady Liberty's pedestal hangs a plaque bearing a slight variant of a quote attributed to Benjamin Franklin circa 1755, "Those who would give up essential Liberty, to purchase a little temporary Safety, deserve neither Liberty nor Safety."
It is duly noted that Franklin and, especially, the ancient Roman Libertas are undoubtedly not contemporary enough to be afforded the consideration of a man as progressive as Bloomberg. But one is forced to wonder how either of the advocates of liberty — real or imagined — from the "olden days" would feel about Bloomberg-era policy initiatives like big soda bans, stop and frisk, and universal surveillance.
Would they simply throw up their arms and mutter, "Times have changed; and the world is too dangerous a place for liberty"?
Post-Boston Gun Sales Offer More Proof That Gun Grabbers' Agenda Is Backfiring
Every time there's a highly publicized violent crime with multiple victims in America, liberals co-opt the tragedy to talk about updating the 2nd Amendment to make the country safer.
Meanwhile, normal Americans go to gun shops and arms themselves against the twofold — but strangely related — threat of domestic terrorism and government tyranny.
Breitbart recounted, on Tuesday, the devotion of attendees at the Syracuse, N.Y., gun show over the weekend. People had to wait two hours in nasty weather just to get inside.
According to one shop owner, the threat of additional terror attacks, combined with ongoing fears that Congress isn't done with fiddling with Constitutional gun rights, had most attendees showing up not to just to browse or sell; they came to buy. The problem is demand is so high that gun selection is limited, and ammunition orders are so far behind that vendors have stopped taking new ones.
Chicago Tribune Mocks Texans Killed By Plant Explosion In Sick Economic Editorial
The Chicago Tribune mockingly referenced the Texas fertilizer plant explosion that took 14 lives last week in a below-the-belt editorial jab at Texas Governor Rick Perry's visit to Illinois in the name of recruiting industry to his State.
Perry his sights on the economically damaged Prairie State recently with a $42,000 radio ad buy in Chicago and another $38,000 in print ads at Crain's Chicago Business, directing people to the website texaswideopenforbusiness.com.
In one of the ads that Chicago-area residents will see, Perry notes, "I have a word of advice for employers frustrated by Illinois' short-sighted approach to business: you need to get out of there while there's still time."
He continues in opining that "the escape route leads straight to Texas" where businesses enjoy "limited government, low taxes and a pro-business environment."
Perry followed up the ad buy with a visit to Illinois this week.
Knowing Perry offers a sweet deal for job makers that their Chicago's liberal political machinations makes impossible to replicate, The Tribune decided to launch a tasteless attack on Texas before pointing out the failures of Illinois politicians in fostering a pro-business environment.
It reads in part:
Laugh all you want about Texas Gov. Rick Perry's campaign to recruit businesses from Illinois to the Lone Star State. We don't know whether Perry will succeed in prompting a commercial exodus from the Land of Lincoln to the land of droughts, fire ants and deadly fertilizer-plant explosions. Yet Perry's stunt is another serious wake-up call for Illinois politicians and the inhospitable business climate they've created.
Perry can boast to Illinois business leaders of a Texas unemployment rate that has fallen to 6.4 percent. That's an excellent barometer of his state's economic health. By contrast, the unemployment rate in Illinois is at 9.5 percent and, as the latest report from the federal Bureau of Labor Statistics indicates, it has been rising over the past year. In March, this state lost 17,800 jobs from the previous month.
That is no laughing matter.
Of course, it is understandable that the editorial board of a newspaper located in a city with such a sordid history, and daily existence, as Chicago would feel comfortable making light of the death of innocent people.
1 In 4 U.S. Teens Misused Or Abused A Prescription Drug
NEW YORK (UPI) – One in four U.S. teens has misused or abused a prescription drug at least once — a 33 percent increase in the past five years, experts say.
A survey by The Partnership at Drugfree.org and MetLife Foundation also found 1-in-8 U.S. teens reported taking the stimulants Ritalin or Adderall not prescribed for them at least once.
Parent permissiveness and lax attitudes toward abuse and misuse of prescription medicines, coupled with teens' ease of access to prescription medicines in the home — often from unused medications in medicine cabinets — are key factors linked to teen medicine misuse and abuse.
Nearly a third of U.S. parents said they believe prescription stimulants such as Ritalin or Adderall, normally prescribed for attention deficit hyperactivity disorder, could improve a teen's academic performance even if the teen did not have ADHD.
Of the children who said they abused prescription medications, 20 percent said they had done so before the age of 14.
More 27 percent mistakenly believe "misusing and abusing prescription drugs to get high is safer than using street drugs," and a third agreed "it's OK to use prescription drugs not prescribed to them to deal with an injury, illness or physical pain."
The 24th annual Partnership Attitude Tracking Study of 3,884 U.S. teens in grades 9-12 and 817 parents has a margin of error for the teen sample of 2.1 percentage points while the margin in the parents' sample was 3.4 percentage points.
CSPI: Chicken, Ground Beef Riskiest When It Comes To Pathogens
WASHINGTON (UPI) — An analysis of some 33,000 cases of foodborne illness found ground beef and chicken were the riskiest meats for germs such as E. coli, a U.S. non-profit says.
Caroline Smith DeWaal, food safety director, of the Center for Science in the Public Interest in Washington, said hospitalizations caused by Salmonella put chicken in the "highest risk" category alongside with ground beef.
Clostridium and norovirus also caused outbreaks associated with chicken, while campylobacter bacteria was also believed to cause a large number of individual illnesses associated with chicken but rarely caused outbreaks, DeWaal said.
"Outbreaks from ground beef and chicken were reported frequently, and all too often caused debilitating illnesses — illnesses that led to hospitalization," DeWaal said in a statement. "For example, approximately a quarter of those who were sickened by Salmonella would go to the hospital. The hospitalization rate for E. coli infections was nearly 50 percent and for Listeria infections it is more than 90 percent."
Chicken nuggets, ham and sausage pose the lowest risk of foodborne illness, DeWaal said.
The report, Risky Meat: A Field Guide to Meat & Poultry Safety, also found meat of high risk included steak and other forms of beef, but excluded roast beef, which was of medium risk. Also of high risk was turkey, often from leaving cooked turkey on the counter too long.
Medium risk meat included barbecue, deli meat, pork — excluding ham and sausage — and roast beef.
The CSPI stressed the analysis only assessed food safety risk and did not address nutrition or the healthiness of the meat.
When Looking For Something Lost, Brain Becomes 'Search Engine'
BERKELEY, Calif. (UPI) — When searching for a lost item, animal or person, various regions of the human brain will switch from other tasks to join in the search, U.S. researchers say.
For example, they said, if a person is looking for a child lost in a crowd, some brain areas usually dedicated to recognizing other objects, or even areas engaged in abstract thought, will shift focus and join the search.
To turn into a highly focused child-finder, the brain temporarily redirects resources it uses for other mental tasks, scientists at the University of California, Berkeley, reported.
"Our results show that our brains are much more dynamic than previously thought, rapidly reallocating resources based on behavioral demands, and optimizing our performance by increasing the precision with which we can perform relevant tasks," neuroscience postdoctoral researcher Tolga Cukur said.
The findings shed light on how people shift attention to challenging tasks, he said.
"As you plan your day at work, for example, more of the brain is devoted to processing time, tasks, goals and rewards, [but] as you search for your cat, more of the brain becomes involved in recognition of animals," he said.
The study can help explain why we find it difficult to concentrate on more than one task at a time, he said, and may provide greater insight into neurobehavioral and attention deficit disorders.
Earth's Pollinating Insects Face Risks That Threaten World Food Supply
LONDON (UPI) — Pollinating insects, vital to global food supplies, face a "cocktail" of multiple pressures putting their survival at risk, a British-led study indicated.
Insects provide pollination activities to about 75 percent of the world's crop species and their decline or loss could have profound environmental, human health and economic consequences, Britain's Center for Ecology and Hydrology reported Monday.
Forty scientists from 27 institutions involved in Britain's Insect Pollinators Initiative, a $15 million research program investigating the causes and consequences of pollinator decline, published a review of the threats in the journal "Frontiers in Ecology and the Environment."
"There is no single smoking gun behind pollinator declines, instead there is a cocktail of multiple pressures that can combine to threaten these insects," review leader Adam Vanbergen said.
"For example, the loss of food resources in intensively farmed landscapes, pesticides and diseases are individually important threats but are also likely to combine and exacerbate the negative impacts on pollinators."
Pollinator populations are declining in many regions, creating threats to human food supplies and ecosystem functions, the scientists said as they urged governments to take steps to address the problem.
"The costs of taking action now to tackle the multiple threats to pollinators is much smaller than the long-term costs to our food security and ecosystem stability," study co-author Simon Potts from the University of Reading said. "Failure by governments to take decisive steps now only sets us up for bigger problems in the future."
China Tops List Of Sources Of Cyber-Espionage Attacks In 2012
NEW YORK (UPI) — China was the main source of cyber-espionage attacks in 2012, with Chinese IP addresses accounting for 30 percent of data breaches worldwide, a report says.
Ninety-six percent of those attacks were made for online espionage purposes, the 2013 Data Breach Investigation Report prepared by Verizon said.
China was the only Asian country on the top 10 threat origins list, the report released Monday said.
Romania came in second at 28 percent of the 2012 data breaches and the United States was third with 18 percent, the report added.
The vast majority of attacks from China were linked to cyber-espionage-related motivations, in contrast to the other countries on the list whose data breaches were mostly financially motivated, it said.
"This may mean that other threat groups perform their activities with greater stealth and subterfuge, but it could also mean that China is, in fact, the most active source of national and industrial espionage in the world today," the report said.
However, a Verizon official said, the high number of data breaches attributed to China doesn't necessarily mean it is the most active perpetrator of cyber-espionage activities.
The number could be because Internet regulation in China is not as strict as other countries, attracting criminals to use it as a base of hacking activities, Patrick Lum, senior consultant at Verizon Business, told ZDNet Asia.
"We are not going with the 'China is bad and scary' message. Rather, it's certainly big and an important part of the entire picture, and it is definitely an up and coming [trend] in the security landscape," Lum said.
Motion Detection System Could Prevent Injuries To Pitchers' Arms
MAYWOOD, Ill. (UPI) — U.S. sports medicine experts say a new motion detection system could identify baseball pitchers who are at risk of shoulder injuries.
While existing systems that evaluate pitchers' throwing motions require cameras and other sophisticated equipment and generally are confined to indoor use, the new system can be used on the field and requires only a laptop computer, researchers at Loyola University reported Tuesday.
In a well-rested pitcher, the upper arm bone and the shoulder blade move in concert, dubbed the scapulo-humeral rhythm. But after a pitcher has been on the mound for a while, the muscles begin to tire, and that rhythm begins to deteriorate, which can lead to shoulder injuries.
The Loyola system, called the Xbus Kit, positions sensors on the pitcher's arms and torso that gather information using gyroscopes, magnetometers and accelerometers to detect deterioration in the scapulo-humeral rhythm.
The study demonstrates the feasibility of using the portable tracking system to identify college-age pitchers who are at risk for shoulder injuries, Loyola University Medical Center sports medicine surgeon Pietro Tonino said.
Such at-risk pitchers could undergo strengthening exercises and physical therapy to prevent injures, he said.
There are plans to next test the tracking system on Little League pitchers, Tonino and his study colleagues said.
Giant Panda Habitats Mostly Spared In Deadly China Earthquake
PMYA'AN, China (UPI) — The 7.0-magnitude earthquake that shook China's Sichuan Province Saturday has had only limited effects on the region's giant panda habitats, officials said.
Little signs of major effects were seen in habitats close to the temblor's epicenter, the Chinese Academy of Sciences said Tuesday.
Aerial remote sensing images showed the scale of landslides triggered by the quake in a giant panda research center in badly hit Baoxing County hadn't been large, China's state-run Xinhua news agency reported.
All 60 giant pandas and nearly 100 staff at Bifengxia Panda Base 30 miles from the epicenter, are safe, officials said.
Buildings in the panda center suffered minor damage, Heng Yi, director of its publicity department, said.
Across the Sichuan Province the earthquake killed 186 people and sent more than 8,000 to hospitals for treatment of injuries.
UPDATE: Eighth-Grader Jailed For NRA Shirt At School Returns To Class — In The Same Shirt
A West Virginia eighth-grader who was suspended and arrested for wearing a National Rifle Association T-shirt to school showed up for his first day back at class wearing the very shirt that originally drew all the unwanted attention from one school employee.
But there was a little vindication this time: Lots of kids showed their support by donning the same shirt, with no apparent threat of suspension or arrest.
Police in Logan, W. Va., told the student, Jared Marcum, he'd been charged with obstruction and disturbing the education process, although Marcum's attorney said he won't be formally charged until after prosecuting attorneys had thoroughly investigated what initially took place.
Marcum's father has requested a copy of a surveillance video that may show the initial incident that led to the suspension and arrest. The school has not disputed that Marcum behaved with civility when he was first confronted by a school official about the shirt, which depicts a hunting rifle above the slogan "protect your right."
LAX Emergency Message Error, Triggered By Worker
LOS ANGELES, (UPI) — A contract worker accidentally triggered an emergency evacuation message on flight status screens at Los Angeles International Airport, a spokesman said.
The message read, "Emergency Leave the Terminal," the Los Angeles Times reported, and was displayed for about 5 minutes in one of the terminals at around 10 p.m.
Travelers noticed the sign and quickly alerted airport officials, the Times said.
Law enforcement officers began searching for who was responsible for the breach and reviewed computer records to determine who may have hacked the system.
But airport officials said at 2 a.m. Tuesday the display of the message was triggered by accident by an airline contract worker with authorized access to the system.
Neighbors Bill Hotel For Loud Late-Night Parties
NEW YORK, (UPI) — Neighbors of the noisy Gansevoort Park Avenue in New York said they are sending mock bills to the hotel to get compensation for their lost sleep.
Residents of the Murray Hill neighborhood said the hotel's loud parties often keep them up until 4 a.m., and six of the residents said they have sent official-looking mock invoices to the hotel seeking $1,000 for each hour of lost sleep, the New York Post reported Monday.
The group said their bills totaled $21,350 for April 14, the night of a particularly wild celebration at the hotel.
"It's a circus. The situation is absolutely unbearable," neighbor Mario Messina said.
"They give great lip service, but the only thing they pay attention to is their wallets," Messina said of hotel executives.
Hotel representatives did not respond to calls and emails requesting comments.
Rookie Anchor Uses Profanity During News Broadcast
BISMARCK, N.D., (UPI) — A rookie newscaster in North Dakota was suspended for using profanity at the very start of his inaugural broadcast.
A.J. Clemente, a new anchor at KFYR-TV, Bismarck, N.D., mumbled profane terms for fornication and excrement about 15 seconds into his first shift in front of the camera Sunday, the New York Post reported Monday.
Co-anchor Van Tieu continued the broadcast as if nothing had happened.
"You may have seen our newest reporter A.J. on North Dakota News and he'll be joining the weekend news team as my co-anchor," she said.
However Clemente may have been on his last broadcast as he was suspended following the incident.
The network apologized for the language.
"We can't take back what was said … all we can do at this point is ask for your forgiveness," News Director Monica Hannan said in a statement.
Clemente acknowledged his mistake on Twitter after the broadcast.
"That couldn't have gone any worse," he tweeted.
Woman Turned Away From Tanning Due To Weight
NORTON, Ohio, (UPI) — An Ohio woman said she is trying to get a refund from a tanning salon after being told she was too heavy to use the business's equipment.
Kelly McGrevey said she bought a tanning package at Aloha Tanning in Norton, Ohio and used a stand-up bed last week during an introductory tour of the business. However, she was turned away when she returned the next day, WKYC-TV, Cleveland, reported Monday.
McGrevey said she was told the stand-up bed was out of service.
"He said, 'Sorry, but I'm not going to let you tan today because we've just implemented a new policy where anyone over 230 pounds can't go in one of our beds,'" McGrevey said. "I was just so shocked and embarrassed and humiliated."
"It really upset me. It's discrimination," McGrevey said.
McGrevey said the worker refused to refund her $70 payment for the monthlong tanning package.
"I said, 'OK, I'd like my money back then. He said, no, we don't give refunds. I said, 'You're not going to give me a refund, I paid for a service that I'm not getting, and he said no, you can't have a refund," McGrevey said.
McGrevey has filed a police report against Justin Hileman, the owner of Aloha Tanning.
She said workers refused to show documentation of the 230-pound weight limit policy.
WKYC-TV said it spoke with a worker who said the business doesn't intend to refund McGrevey's money.
Edited, Three-Hour 'Bible' Getting A Theatrical Release
LOS ANGELES, (UPI) — Producer Mark Burnett says "The Bible," his highly rated, 10-part American TV miniseries, will be pared down and released as a three-hour film in theaters.
"We're cutting a movie version right now, a three-hour version of Jesus and [we have] many, many offers from theaters globally," executive producer Mark Burnett told The Hollywood Reporter.
Burnett said the movie version, which will focus largely on Jesus Christ's resurrection, is expected to open in theaters this fall.
Boston Bombers May Have Planned NYC Attack
BOSTON, (UPI) — The carjacking victim of the Boston Marathon bombing suspects has opened up the possibility the pair was planning a New York City attack, investigators said.
The investigators told CBS news the cache of weapons Tamerlan and Dzhokhar Tsarnaev allegedly compiled hints at plans for another attack and the brothers may have planned to go to New York.
The carjacking victim speaks little or no English but he was able to recognize certain words as the brothers conversed first in English and then in Russian.
One of the words he recognized was "Manhattan," investigators told CBS.
That resulted in a search of all Amtrak trains from Boston to New York last week and prompted New York to turn on its network of license plate readers at all bridges and tunnels coming into the city.
Surviving brother Dzhokhar Tsarnaev, 19, continued to answer questions in writing from his hospital bed Monday night.
Tsarnaev blamed his dead older brother for being behind the deadly bomb attacks, a U.S. government source told CNN.
Tsarnaev, charged Monday with using a weapon of mass destruction that resulted in three deaths and more than 260 injuries, also said he and his brother, Tamerlan, 26, were not involved with any international terror groups, the network reported.
Earlier reports said 170 people had been injured.
Nick Martin, a spokesman for the Boston Public Health Commission, said the new figures were based on date from 25 area hospitals.
"A lot of people were injured in the blasts, but didn't think it was serious at the time," Martin told The Boston Herald. "But when their symptoms didn't go away a day or two later, they decided to have a medical professional check them out.
The New York Times separately quoted law enforcement officials as saying Dzhokhar Tsarnaev, still laying badly wounded in a Boston hospital bed, admitted he helped place the bombs.
The newspaper said he also told investigators he and his brother acted alone and said he knew of no other plots and no other bombs that had not been detonated.
The early interviews with Tsarnaev indicated the two brothers fit the profile of self-radicalized jihadis, the government source told CNN.
The younger brother told investigators his brother — killed early Friday — wanted to defend Islam from attack, CNN quoted its source as saying.
The charges were conveyed to Tsarnaev in his hospital room in the intensive care ward of Beth Israel Deaconess Medical Center, where he is recovering from multiple gunshot wounds.
His bedside initial court appearance was conducted by U.S. Magistrate Marianne B. Bowler.
Tsarnaev was able to respond to inquiries, nodding yes and at one point saying, "No," a transcript of the hearing indicated.
At the end of the session, Bowler said: "At this time, at the conclusion of the initial appearance, I find that the defendant is alert, mentally competent and lucid. He is aware of the nature of the proceedings."
If convicted, Tsarnaev faces a possible death sentence or life in prison.
His next hearing was set for May 30, court officials said.
His public defender had no immediate comment.
TSA Backpedals On Allowing Knives On Planes
LOS ANGELES, (UPI) — The Transportation Security Administration chief announced a delay in a policy change that would have allowed small folding knives onto U.S. flights this week.
TSA chief John Pistole did not say whether he would reconsider lifting the knife ban at a later date, the Los Angeles Times reported Tuesday.
Opponents of allowing knives on planes said Pistole reversed the proposed change after backlash from flight attendants, airline executives, lawmakers and the families of the victims of the Sept. 11, 2001, terrorist attacks.
"So we can incorporate their input and to continue training requirements nationwide, I have decided to temporarily delay implementing the prohibited items changes," he said Monday in a letter to TSA workers.
Under the rule change that was set to go into effect Thursday, passengers would have been allowed to carry small knives, no longer than 2.36 inches long and less than a half-inch wide, as well as pool cues, ski poles, hockey sticks, lacrosse sticks, golf clubs and novelty-size bats.
"The United States has banned all knives from commercial flights since the Sept. 11, 2001, attacks for good reason: Knives were the terrorists' weapons of choice in bringing down four jetliners and murdering thousands of Americans," a coalition of flight attendants said in a statement.


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The Onalaska Library
Evening Book Club
meets on the second Thursday of each month at 6:30pm
Onalaska Library Meeting Room
Thursday, May 14th
The Husband's Secret
by Liane Moriarty
Copies are available through the La Crosse County Library.
Book groups are a great way to appreciate books and socialize at the same time.
The public is always welcome.
Upcoming Selections: Subject to change
June My Antonia by Willa Carter
July Ordinary Grace by William Kent Krueger
August Still Alice by Lisa Genova
September Devil in the White City by Erk Larson
October The Storied Life of A.J. Fikry by Gabrielle Zevin


text:
July 4, 2015
Knoxville, (WVLT-TV), Our countdown to kickoff continues
with the Union County Patriots.
Last season, the Pats certainly didn't live up to the standards
set by the NFL team which goes by the same nickname.
Union County tallied just one game in the win
column, but Danny Satterfield's Patriots have been working
hard all summer and posses the team speed needed to
make a serious run through a difficult District.
The Patriots open the season at home Friday August 19th against
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My Western Horse 3D has no review on Wii's World.
No posts yet for this game. Be a pioneer.
Nintendo has detailed the return of its World Championship
Do you have what it takes?
Disney Infinity 3.0 Edition Officially Revealed
The Force is strong with this one...
Rumor: Disney Infinity 3.0 Leaked Early
Straight from a Galaxy Far, Far Away...
Mario Kart 8 DLC Pack 2...OH YEAAAAH!
Nintendo should do this more.
The Nintendo GameCube: An Interesting Legacy
Will The Wii U Have a Similar Fate?
Project Ukulele - Possible Hint at Characters
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Free to Play Pokemon Shuffle now available on 3DS eShop
Nintendo offers another micro-transaction based title
Gold Mario Amiibo is a Wal-Mart Exclusive
Get ready to shell out your coins
Area Effect Announces Izle for Wii U
Part action, part adventure, all cel-shaded
Nintendo Confirmed As Sponsor For APEX 2015
Another positive step for the Smash competitive scene
Football Up Online
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Best of Solitaire
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PUZZLEBOX setup
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Toys vs Monsters
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Kiara Hartwick said:
No... I have ZERO interest and care for them ... Collecting amiibo figures
Kiara Hartwick said:
I don't know if the Wii U will still be popular, but I like playing Wii U because not only can it play new Wii U games, ... The Nintendo GameCube: An Interesting Legacy
tyler674 said:
hi ... Kart Racer
Kiara Hartwick said:
The Eternal Night was one of the best games ever in my opinion, I've never played crash of the titans though ... New Crash and Spyro games?
Kiara Hartwick said:
I wonder who their parents are :P ... Shigeru Miyamoto: Mario has no last name
Wii's World is not officially affiliated with Nintendo! (but they wish we were).


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1257 Historic Route 66
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Accessibility links
Key contacts
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Complaints and feedback
Corporation departments
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One Lime Street
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Lloyd's occupies sites in both London and Chatham.
find out more
+44 (0)20 7327 6125
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Press Centre
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A Lloyd's account gives market participants such as underwriters, brokers and coverholders access to enhanced content and services. If you are not a market participant you can also create an account to sign up for email news and updates from Lloyd's.
Mon 16 Dec 2013
Lloyd's has today announced that Inga Beale will take the reins as CEO, succeeding Richard Ward.
Beale comes to Lloyd's with three decades of international insurance and reinsurance experience.
Most recently, she has been Group Chief Executive of Canopius, the prominent Lloyd's managing agent. Prior to that she spent four years with Zurich Insurance, including a period as Global Chief Underwriting Officer, and was Group CEO of Converium Ltd, the Swiss mid-sized independent reinsurance company.
While at Converium, she led a major turnaround of the business before it was acquired by SCOR in 2007. Beale started her career as an underwriter with Prudential before spending 14 years in a variety of international roles for GE Insurance Solutions.
John Nelson, Chairman of Lloyd's, said: "I am absolutely delighted that we have appointed Inga as Chief Executive. She has 30 years' experience in the insurance industry. Her CEO experience, underwriting background, international experience and operational skills, together with her knowledge of the Lloyd's market, make Inga the ideal Chief Executive for Lloyd's. I very much look forward to working with her."
Beale will start at Lloyd's in January 2014 and is looking forward to both the opportunities and challenges she will face in the new role.
She said: "Lloyd's is already an international leader, but this unique market has an extraordinary opportunity to increase its footprint and to cement its position as the global hub for specialist insurance and reinsurance. I'm looking forward to working with the Lloyd's team and the wider market to deliver a strategy for profitable and sustainable growth alongside Lloyd's robust market oversight."
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Lloyd's Patriotic Fund is supporting the UK's Armed Forces Day on 27 June 2015 by making a donation of £250,000 to two armed services charities:...
Lloyd's has become aware following a consumer enquiry that a business known as "AAOption", which falsely alleges that it is protected by Lloyd's.
Lloyd's Japan and Sompo Japan Nippon Koa Insurance Inc. launch a new facility to support M&A activity in Japan.
In partnership with the ABI, Lloyd's presents a basic guide to cyber insurance.
With 81% of large UK businesses and 60% of small companies suffering a cyber security breach in the last year, a new report published by HM...
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VIEWS: 8 PAGES: 4 CATEGORY: Education POSTED ON: 5/12/2010 Public Domain
Age and Ageing 2000; 29: 301–304 2000, British Geriatrics Society REVIEW Osteoporosis and the role of vitamin D and calcium–vitamin D deficiency, vitamin D insufficiency and vitamin D sufficiency OPINDER SAHOTA1,2 1 Ageing and Disability Research Unit, B floor, Medical School, Queen's Medical Centre, University Hospital, Nottingham NG7 2UH, UK 2 Division of Mineral Metabolism, City Hospital, Nottingham, UK Address correspondence to: O. Sahota. Fax: (+44) 115 9423618. Email: email@example.com Keywords: calcium, osteoporosis, vitamin D, vitamin D deficiency, vitamin D insufficiency, parathyroid hormone Introduction of hormones, of which parathyroid hormone and vitamin D play a major role (Figure 1). Vitamin D is The skeleton consists of cortical bone (70–80%) and derived from plant (vitamin D2; ergocalciferol) and trabecular bone (20–30%). In the normal axial skele- animal sources (vitamin D3; cholecalciferol) in the diet ton, about 25% of the anatomic bone volume is specific and synthesized in the skin (vitamin D3) by ultraviolet bone tissue and 75% bone marrow and fat, but this radiation of 7-dehydrocholesterol. Vitamin D2 and varies widely between different parts of the skeleton. vitamin D3 are biologically interchangeable although Of the specific bone tissue, only 60% is bone mineral they differ in their rates of metabolism. and 40% is organic matter, mainly collagen. Bone Vitamin D (D3 and D2 collectively) is transported to marrow consists of a stroma, myeloid tissue, fat cells, the liver, bound to a specific a-globulin (vitamin D- blood vessels, sinusoids and some lymphatic tissue. binding protein) and to a small extent albumin and The yellow marrow contains mainly fat cells and the lipoproteins. It is hydroxylated to 25-hydroxylated red marrow mainly erythropoeitic tissue elements. vitamin D—25(OH)D; calcidiol—which is the major With advancing age, the proportion of red marrow circulating vitamin D metabolite in the body. This passes decreases as red marrow is replaced with yellow to the kidney where it is further hydroxylated by 1a- marrow, although at any age, the proportion of hydroxylase to form 1,25-dihydroxy vitamin D— yellow and red marrow varies with the skeletal site. 1,25(OH)2D. This is the active metabolite and increases Bone tissue is a complex, metabolically active organ ECF-Ca2þ by increasing calcium and phosphate absorption of which the bone mineral is composed essentially of from the gut and mobilizing calcium from bone. calcium and phosphate salts. These salts account for Parathyroid hormone is synthesized by the para- about two-thirds of the total dry weight of bone and most thyroid gland and maintains the short-term homeostasis of total body calcium and phosphate. They are essential of ECF-Ca2þ through its effects on the kidney (increased for normal skeletal growth, the maintenance of skeletal calcium re-absorption) and mobilization of calcium from mechanical integrity and as a pool for the extracellular the labile bone pool. A more sustained response is calcium compartment. The body contains about 1000 g produced through the regulation of the renal production (2500 mmol) of calcium, of which 9 g (225 mmol) is in of 1,25(OH)2D [1]. Parathyroid hormone is the major the soft tissues, 1 g (25 mmol) in the extracellular fluid regulator of 1,25(OH)2D production, although serum compartment and the remainder in bone. calcium and serum phosphate also affect its production. The parathyroid hormone–vitamin D axis Vitamin D and skeletal pathophysiology The homeostasis of extracellular ionized plasma The mechanical integrity and structure of skeleton is calcium (ECF-Ca2þ ) is tightly regulated by a number maintained by the constant remodelling of bone which 301 O. Sahota impaired 1a-hydroxylation of the ageing kidney, despite normal renal function [12]. Vitamin insuffi- ciency is common in adults and in older people living at home. Chapuy and co-workers [13] found that 39% of healthy ambulatory elderly women recruited from the general community in France had a 25(OH)D level of <12 ng/ml. In a further study, they investigated the vitamin D status of a middle-aged general adult urban population (aged 45–65 years) and found that 14% had a 25(OH)D level of <12 ng/ml) [14]. Untreated, vitamin D insufficiency progresses to bone loss and thus increased risk of fracture, but this is further compounded with ageing. Peak bone mass is achieved around the age of 20–30 years, followed by a Figure 1. The parathyroid hormone–vitamin D axis. period of consolidation and then an age-related decline in osteoblastic function, leading to an excess of bone responds to the normal physiological and pathological resorption over formation and consequent bone loss. skeletal stresses of daily living. The required intakes Peak bone mass and rate of bone loss are important in of calcium and vitamin D increase with age, which the development of osteoporosis. However when there unfortunately, these increased levels are seldom is vitamin D insufficiency, bone resorption is amplified, achieved. further increasing fracture risk. This pathophysio- logical process has been recognized in patients present- ing with osteoporotic hip fractures and occurs also in fit Vitamin D deficiency and insufficiency elderly people with established vertebral osteoporosis The major causes of vitamin D deficiency are poor [15], which encompasses most osteoporotic patients nutrition, deprivation of sunlight, consequent decline presenting to doctors. in the synthesis of cutaneous vitamin D3 and decreased The threshold serum concentration of 25(OH)D renal hydroxylation of 25(OH)D by the ageing kidney that defines vitamin D insufficiency has been the [2–4]. subject of much research over the last few years. An Long-lasting and severe vitamin D deficiency leads early sign of vitamin D insufficiency is the secondary in adults to osteomalacia and in children to rickets (a increase in serum parathyroid hormone, which may bone disorder characterized by typical biochemical and still be within the 'upper normal range' [16, 17]. A bone abnormalities), along with defective mineraliza- recent study has shown a parathyroid hormone tion, severe secondary hyperparathyroidism, hypo- threshold effect when serum 25(OH)D was 31 ng/ calcaemia, hypophosphotaemia and an increase in ml [14]. The recommended diagnostic threshold and total alkaline phosphatase. Vitamin D deficiency can be relationship to bone turnover markers and bone confirmed by measuring 25(OH)D levels which are mineral density of the three vitamin D subgroups are usually very low and often undetectable. The pre- shown in Table 1 [18]. valence is high in the institutionalized and housebound elderly population [5, 6]. Vitamin D insufficiency (subclinical vitamin D Therapeutic intervention deficiency) is increasingly being recognized as a distinct pathological entity. In contrast to vitamin D Calcium therapy deficiency, it is characterized by mild secondary hyperparathyroidism, normocalcaemia and normal In adults, calcium supplementation reduces the rate of bone mineralization. The initial fall in ionized plasma age-related bone loss [19]. A review of 20 prospective calcium stimulates parathyroid hormone secretion, studies concluded that calcium supplementation which in turn stimulates renal 1a-hydroxylase and reduced bone loss on average by about 1% per year increases 1,25(OH)2D production. This restores serum in postmenopausal women [20]. The effect of calcium calcium to the normal set-point for that individual [7], in reducing the incidence of fractures has, however, but at the expense of increased bone turnover, and been inconsistent. Recker et al. [21] found that 1200 prevents the emergence of osteomalacia [8, 9]. mg of calcium daily reduced the incidence of vertebral The increase in 1,25(OH)2D in response to the fractures in women with low calcium intakes and with parathyroid hormone stimulus in vitamin D deficiency one or more vertebral fracture, but did not reduce the has nevertheless been found to be inappropriate and risk of the first vertebral fracture. In contrast, Chevalley remains within the mid–low normal laboratory refer- et al. [22] observed a marked reduction in the incidence of ence range [10, 11]. This may be partly related to the first vertebral fracture with calcium supplementation, degree of substrate [25(OH)D] deficiency and possibly although all patients were vitamin D-replete. Fewer studies 302 Vitamin D, calcium and osteoporosis Table 1. The relationship of the biochemical indices, bone turnover and bone mineral density in vitamin D deficiency, insufficiency and sufficiency Deficiency Insufficiency Sufficiency ............................................................................................................................................. 25(OH)D, ng/ml 0–5 5–30 >30 Parathyroid hormone High High normal Normal 1,25(OH)2D Low/normal Low normal Normal Bone turnover High High normal Normal Bone Osteomalacia/low bone mass Low bone mass Normal 25(OH)D, 25-hydroxylated vitamin D (calcidiol); 1,25(OH)2D, 1,25-dihydroxy vitamin D. have examined the relationship between calcium and hip second fractures was not carried out. Dawson-Hughes fracture risk, and these have produced conflicting and co-workers' study of. patients over the age of 65 results [23, 24]. No studies have evaluated the effects years living at home showed that treatment for 3 years of calcium to reduce the risk of a second hip fracture in with 500 mg of calcium plus 700 IU of vitamin D3 vitamin D-insufficient subjects. increased bone mineral density at both hip and spine [30]. The reduction of non-vertebral fractures Vitamin D therapy was of a similar magnitude to that in Chapuy and co- workers' study, but the absolute numbers of fractures Lips et al. [25] and Ooms et al. [26] have shown that in the study were small. In this study it was daily supplementation with small doses of vitamin D2 unclear what proportion of patients were vitamin D- or vitamin D3 (10–20 mg/day) can reduce the second- insufficient, although there was a 33% mean reduction ary hyperparathyroidism induced by vitamin D insuffi- in parathyroid hormone. ciency and increase bone mineral density, but there have been no prospective randomized controlled trials to evaluate the effect on vertebral fracture rates. Conclusion Studies on hip fracture reduction, as with calcium, have produced conflicting results. Lips et al. [27] Vitamin D and calcium are important in the mechanical showed that 400 IU vitamin D daily for three and a half and structural integrity of the skeleton. Subclinical years had no effect on reducing hip fractures and, vitamin D deficiency (vitamin D insufficiency) is although most subjects were vitamin D-replete, further common in the fit, active elderly population and sub-analysis on the vitamin D-deficient patients simi- leads to an amplification of age-related bone turnover, larly showed no significant reduction in hip fracture bone loss and thus increased risk of fracture, mediated rate. In contrast, Heikinheimo et al. [28] showed that by secondary hyperparathyroidism. Daily supplemen- vitamin D given annually by intramuscular injection tation with vitamin D can reduce the secondary (300 000 IU) resulted in a decrease in non-vertebral hyperparathyroidism and increase bone marrow den- fractures, although sub-analysis only showed a statisti- sity but only combination calcium and vitamin D cally significant reduction in upper limb but not hip therapy has been shown to be effective in reducing fractures. No studies have evaluated the effect of non-vertebral fractures. vitamin D in the reduction of second hip fracture in patients with vitamin D insufficiency. Key points Combination vitamin D and calcium • Vitamin D and calcium are important in the mechanical and structural integrity of the skeleton. The use of combination vitamin D and calcium therapy • Subclinical vitamin D deficiency (vitamin D insuffi- has nevertheless shown a consistent reduction in non- ciency) is common in the fit, active elderly vertebral fractures. Chapuy et al. [29] showed that population and leads to an amplification of age- supplementation with 1.2 g calcium and 800 IU related bone turnover, bone loss and thus increased vitamin D3 over 18 months resulted in a 43% reduction risk of fracture, mediated by secondary hyperpara- in hip fractures and a 32% reduction in the total thyroidism. number of non-vertebral fractures in institutionalized, • Daily supplementation with vitamin D can reduce vitamin D-insufficient elderly women compared with the secondary hyperparathyroidism and increase the placebo group, with a mean reduction of 47% in bone marrow density but only combination calcium secondary hyperparathyroidism. Previous osteoporotic and vitamin D therapy has been shown to be fractures were present in some of these patients, but effective in reducing non-vertebral fractures. sub-analysis of prevalent fractures and the reduction in 303 O. Sahota References 16. McKenna MJ, Freaney R. Secondary hyperparathyroidism in the elderly: Means to defining hypovitaminosis D. Osteop Int 1998; 8 1. Parfitt AM. Bone and plasma calcium homeostasis. Bone 1987; 8: (suppl.): S3–6. S1–5. 17. Scharla SH. Prevalence of subclinical vitamin D deficiency in 2. Gallagher JC, Riggs BL, Eisman J et al. Intestinal calcium different European countries. Osteop Int 1998; 8 (suppl.): S7–12. absorption and serum vitamin D metabolites in normal subjects 18. Peacock M. Effects of calcium and vitamin D insufficiency on the and osteoporotic patients: effects of age and dietary calcium. J Clin skeleton. Osteop Int 1998; 8 (suppl.): S45–51. Invest 1979; 64: 729–36. 19. Nordin BEC. Calcium and osteoporosis. Nutrition 1997; 13: 3. Omdahl JL, Garry PJ, Hunsaker LA et al. Nutritional status in a healthy 664–86. elderly population: vitamin D. Am J Clin Nutr 1982; 36: 1125–33. 20. Dawson-Hughes B, Dallal GE, Krall EA et al. Effect of vitamin D 4. Tsai K-S, Heath H III, Kumar R et al. Impaired vitamin D supplementation on overall bone loss in healthy postmenopausal metabolism with ageing in women. J Clin Invest 1984; 73: 1668–72. women. Ann Intern Med 1991; 115: 505–12. 5. McKenna M. Differences in vitamin D status between countries in 21. Recker RR, Hinders S, Davies KM. Correcting calcium nutritional young adults and in elderly. Am J Med 1992; 93: 69–77. deficiency prevents spine fractures in elderly women. J Bone Miner 6. Gloth III MF, Gundberg CM, Hollis BW et al. Vitamin D deficiency Res 1996; 11; 1961–6. in homebound elderly persons. JAMA 1995; 274: 1683–6. 22. Chevalley T, Rizzoli R, Nydegger V et al. Effects of calcium 7. Brown EM. Extracellular Ca2þ sensing, regulation of parathyroid supplements on femoral bone mineral density and vertebral cell function and role of Ca2þ and other ions as extracellular first fracture rate in vitamin D replete elderly patients. Osteop Int 1994; messengers. Physiol Rev 1991; 71: 371–411. 4: 245–52. 8. Lips P, Netelenbos JC, Jongen MJM et al. Histomorphometric 23. Kanis JA, Johnell O, Gullberg B. Evidence for the efficacy of profile and vitamin D status in patients with femoral neck fracture. bone active drugs in the prevention of hip fracture. BMJ 1991; 305: Metab Bone Dis Rel Res 1982; 4: 85–93. 1124–8. 9. Khaw KT, Sneyd MJ, Compston J. Bone density, parathyroid 24. Pagannini-Hill A, Ross RK, Gerkins VR et al. Menopausal hormone and 25-hydroxyvitamin D concentrations in middle aged oestrogen therapy and hip fractures. Ann Intern Med 1981; 95: 28–31. women. BMJ 1992; 305: 273–7. 25. Lips P, Wierzinga A, Van Ginkel FC et al. The effect of vitamin D 10. Chapuy M-C, Chapuy P, Meunier PJ. Effect of calcium on vitamin supplementation on vitamin D status and parathyroid function in D supplements on calcium metabolism in the elderly. Am J Clin Nutr elderly subjects. J Clin Endocrinol Metab 1988; 67: 644–50. 1987; 46: 324–8. 26. Ooms ME, Roos JC, Bezemer PD et al. Prevention of bone loss by ˚ 11. Akesson K, Lau K-HW, Baylink DJ. Rationale for active vitamin D vitamin D supplementation in elderly women: a randomised double analogue therapy in senile osteoporosis. Calcif Tissue Int 1997; 60: blind trial. J Clin Endocrinol Metab 1995; 80: 1052–8. 100–5. 27. Lips P, Graafmans WC, Ooms ME et al. Vitamin D supplementa- 12. DeLuca HF. 1,25 dihydroxyvitamin D3 in the pathogenesis and tion and fracture incidence in elderly persons: a randomised placebo- treatment of osteoporosis. Osteop Int 1997; 7: S24–9. controlled trial. Ann Intern Med 1996; 124: 400–6. 13. Chapuy MC, Schott AM, Garnero P et al. Healthy elderly French 28. Heikinheimo RJ, Inkovaara JA, Haavisto MV et al. Annual women living at home have secondary hyperparathyroidism and high injections of vitamin D and fractures of aged bones. Calcif Tissue bone turnover in winter. J Clin Endocrinol Metab 1996; 81: 1129–33. Int 1992; 51: 105–10. 14. Chapuy MC, Preziosi P, Maamer M et al. Prevalence of vitamin 29. Chapuy MC, Arlot ME, Delmas PD et al. The effect of calcium and D insufficiency in an adult normal population. Osteop Int 1997; 7: cholecalciferol treatment for three years on hip fractures in elderly 439–43. women. BMJ 1994; 308: 1081–2. 15. Sahota O, Masud T, San P et al. Vitamin D insufficiency increases 30. Dawson-Hughes B, Harris SS, Krall EA et al. Effect of calcium and bone turnover markers and enhances bone loss at the hip in patients vitamin D supplementation on bone density in men and women 65 with established vertebral osteoporosis. Clin Endocrinol 1999; 51: years of age or older. N Engl J Med 1997; 337: 670–6. 217–21. 304
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Brew at the Zoo & Wine, Too!
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Endow Kentucky Tax Credit Seminar - October 19, 2012
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Friday, October 19, 2012 from 9:00 AM to 10:00 AM (EDT)
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Comment: Re: father time (Score 1) 287 287
Comment: Re:Anonymous cannot be trusted (Score 1) 363 363
I'm not going to defend Anonymous or feel bad if they are prosecuted for their actions. They decided two wrongs make a right and have to live with any consequences. The same applies to the foam pie thrower.
Comment: Re:Anonymous cannot be trusted (Score 2) 363 363
Why Creators Should Never Read Their Forums 221 221
Linux 2.6.37 Released 135 135
The Fuel Cost of Obesity 285 285
Comment: Re:Diesel (Score 1) 1141 1141
Diesel is not as clean as gasoline (no matter what the oil companies say).
That's true, but misleading in this context. Diesel fuel is denser than unleaded gasoline, and is more fuel efficient overall. Diesel releases less greenhouse gas for the distance traveled. This is because the increased emissions — which are about 15% higher — are more than offset by the increased fuel efficiency of diesel fuel engines — which are about 30% more efficient on average.
Comment: Re:Screw Godwin (Score 1) 278 278
To paraphrase Freud, sometimes a Nazi is just a well-known example of some of the worst in the human race. As the extreme terminator of a range definition whose other end was "Greek Democracy", it sets an appropriate boundary
There's Godwinism and there's False Godwinism.
Greek Democracy... so now you're advocating slavery?
Comment: Re:why do people work for Raytheon? (Score 1) 278 278
Comment: Re:Troubleshooting skills. (Score 1) 829 829
Comment: Different Perspective (Score 4, Interesting) 205 205
For those of you complaining about the jerky video: STFU!
For those of you saying it isn't practical: So What!
I want to take my hat off to these dudes and give them a hearty round of applause and say "Great job guys!"
My point here is these guys had a vision, that led to an idea, that lead to an exparament where a couple of pretty normal folks did something extrodinary. It is the same kind of curiosity that Ben Franklin had when he flew the kite and "discovered" electricity.
Those of you who have offered criticisim, I ask you to reply to this post and tell me what you have done without backing that approximates or bests their very cool accomplishment.
Those of you who have a vision share it, maybe someone will help you make it an idea so, I invite you to share your vision.
For those of you who have an idea, share it and maybe someone will help you make it real.
We don't need government, business, or universities to make the world a better place; just a few ordinary folks who try to do extrodinary things!
Those of you who think this is just very cool, use this thread to virtually offer your applause and (real) encouraging comments!
Comment: Re:interest prospect (Score 1) 194 194
Heavy or organic pollutants which radically alter metabolism, and heat, are two completely different things. One can kill a lot of stuff in small quantities, the other is pumped in by the sun, all the time, and is considered part of the status quo.
You can kill all of the bacteria in a pot of water by adding a couple drops of bleach, but you have to add a huge amount of energy to achieve the same effect.
(I worry that you barely read my post, because I did prefix that statement with "when it comes to energy" specifically to keep you from wasting a line on mentioning something like interplanetary travel =/ )
When I said "human scale" I meant, "within human capacity to change." Right now, we could (and have) overheat medium-sized lakes with our coal, nuclear, "hot" power plants. We overcool other bodies of water with the reservoirs of hydroelectric power plants. Chemically, we can take out small to medium-sized ecosystems, physically, we can chop down, drain, or otherwise displace bigger ones. But heat? Even if we dedicated the whole of human activity to (directly*) heating the oceans, we'd be completely incapable of making a dent.
This post makes the basic point rather vividly: http://news.slashdot.org/comments.pl?sid=1376893&cid=29497453
5.6*10^24J is not the kind of energy humans, as a species, can hope to move from the land to the sea. And that's for 1 degree.
As it stands, our current means of cooling uses the atmosphere, in a less-efficient process. As the same post mentions, the atmosphere is less massive and has a much lower specific heat. If you're worried about screwing up the environment, using ocean-based cooling is exactly the kind of thing you'd be into, as it is more efficient, and is placed into a system that is very capable of dealing with it.
*Directly, as in the thermal result of combustion or electrical resistance (or giant orbital doom-mirrors), as, indirectly, chemically, it appears to be very much within our capacity (read: atmospheric hydrocarbons.)
Comment: Re:Eyecandy in cost of usability (Score 1) 1124 1124
While they don't publish all of the data, there is a video (about an hour long) that they posted to MSDN that introduces the Ribbon and all of the variations that went into creating it.
In one particular scene, they show data collected from one week's use of most Office 2003 apps. In the video they've ranked all of the features used in Word, Outlook, etc, by number of times used.
In Word, the most commonly accessed feature was Paste. In today's ribbon, where do you see paste? It's the very first icon on the Home tab.
I train people on Microsoft Office for a living. Everyone I've trained on Office 2007 has said how much easier it is to use than 2003. Hunting for common options is no longer a common activity.
There comes a point where a program becomes so complicated, menus don't cut it. The ribbon solves that problem beautifully, and Office 2010 refines it even further.


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Layered Heart Collages
Activity DesignerMelissa Klinker
46 Projects
What You'll Need
How We Did It
Have your child start gluing and sticking the sequins and foam stickers on the cut out heart shapes. They can be overlapped or put side by side. Have fun with it. That's the beauty of collages -- anything goes!
Once your collage is dry, mark a spot near the top signifying where you would like to hang it. Push your pen tip through the spot, making a hole in the foam. Next, thread your twine through the hole.