text:
Unlike the woman I drew in this cartoon, I have not walked, run or biked for Breast Cancer awareness. I am very grateful to those who do because it is so crucial that we raise understanding and money for the research that can put an end to this horrible disease.
Read Whole Story
The Keep A Breast Foundation made plaster molds of women's busts and auctioned them off to raise funds for breast cancer awareness. I thought this was a fantastic idea. I emailed them immediately, and days before my reconstructive surgery, I had a plaster mold made of my torso.
Talk with your doctor about the Gail Model and find out what your level of risk for breast cancer is. And get a mammogram.
An odd feeling comes over me as fall starts to creep into late summer. It isn't necessary to consult a calendar to know that all my cancer anniversaries are lining up.
You should think before you pink, as you might before giving to any solicitor of charitable funds. But let's not argue about the color and the ribbon which was, 20 years ago, an emblem of openness about a disease that women were afraid to mention out loud.
In honor of Breast Cancer Awareness Month, the NFL has turned pink for the last four weekends. Everything from pink hand towels to pink game balls and...
An emotional Kathie Lee Gifford and Hoda Kotb celebrated a major milestone during the fourth hour of Thursday's "Today" show.
Kotb, who was diagnos...
I have finally pinpointed why this pink month drives me crazy. It's because of its failure to understand what all of this awareness does to breast cancer's most silent victims -- women that live with the threat of breast cancer hanging over their heads. Women like me.
Athletes Kevin Love and Larry Fitzgerald are raising awareness for breast cancer in an amazing way.
Fitzgerald, an Arizona Cardinal's wide receive...
In honor of Breast Cancer Awareness month, I sat down recently with Florence Williams, author of the book, BREASTS: A Natural and Unnatural History, to talk about breast health and what's really in our breast milk.
October is Breast Cancer Awareness Month, the time of year when many athletes and celebrities use their fame to perform outrageous stunts for a good c...
I asked Lucy why she was telling people that I had back surgery. She said, "Well, it's easier than telling them about the front." We'll, I'll give you that, Lucy. I love that she makes me laugh.
I saw the people who have held my hand, poked me with needles, taken my vital signs and treated my cancer, and I saw them for once in a non-medical way. They were not in white coats and sneakers or scrubs -- they were laughing, eating and drinking cocktails.
It's wrong to trivialize women. It's wrong to trivialize a deadly disease. And I have to ask would this be acceptable if we were dealing with male body parts or a man's disease? Where is the feminism in breast cancer awareness?
Nick Eason is used to beating up on opponents, but this time, the Arizona Cardinals defensive end is tackling another enemy: breast cancer.
In a vi...
Darlene has breast cancer. She never asked, "Why me?" Right from the beginning, she decided that she was going to bring a positive outlook to her situation, to the very best of her ability.
October is Breast Cancer Awareness Month, a time we typically associate with women, mothers, and pink ribbons. But what many of us don't realize is th...
Each October the ribbons return, the fund-raisers reboot, and newspaper headlines everywhere become overwhelmingly breast-centric. So you couldn't b...
October 2012. We've been glowing pink all month, celebrating victories and being mindful of the need to eradicate breast cancer.
The Hope Bus, a mobile wellness and resource center that also happens to be a glorious pink 37-foot RV, delivers programs, services and resources across Rhode Island and into Massachusetts.
In what's being touted as the largest analysis of breast cancer screening methods for women under the age of 40, researchers at the Seattle Cancer Car...
There are common breast cancer awareness bumper stickers and T-shirts that state, "Save the the ta-tas." It is not called ta-ta cancer. It is called breast cancer, and it kills.
Pain and sadness are important and valuable feelings that need to be processed during and after any rotten experience. The beauty of Silver Linings is that they don't take away the rain. Rather, they provide an umbrella.
Your doctor won't force you to return to their office for a follow-up. Don't wait for your insurance company to send a town car to take you for a scan. You are responsible.
By continuing to condone the use of this terminology in breast cancer awareness campaigns, women send the message that we're okay with the objectification of women and our "boobies."
Get top stories and blog posts emailed to me each day..


text:
Kamisama Hajimemashita by nipuniWatch
©2012-2015 nipuni
hello! well we finally brought our pcs to the new apartment but we still had to wait for fucking ever until they installed internet here, so i drew and watched anime and drew some more, so i have some stuff to post now at least.
I'm watching this show and many others :> I'ts cute
I'm watching this show and many others :> I'ts cute
It almost looks like Nanami has a kitsune tail but nah, Tomoe is the only lovely kitsune. X3
This looks awesome, love the detail!
Oh,Tomoe looks so beautiful :33
This is so beautiful and amazingly done! You did them both so very well
sooo cute x3
can I borrow this art?
as long as you credit me and don't sell it, sure go ahead :>
omfg @u@
it's the best art with Tomoe i've ever seen
it's the best art with Tomoe i've ever seen
IT really is adorable, awesome
I love this series : ) And I think that's the most beautiful fan art of those two I've seen : )
wow good work.
Wow, that's really good! So cute!
I still need to watch the anime (I'm reading the manga though).
I still need to watch the anime (I'm reading the manga though).
*_* Luvvv
i love this show i get the ending song stuck in my head frequently .... ah ah ah ah~ ah ah ah ah~
Right?! That song is so catchy!
Cute. And nice kimono.
Tomoe is extremely well done it seems like it was taken right from the anime, and Nanami is even cuter! *w*
I love this show too. xD It's a cute romance. Beautiful fanart!
WANNA THE TERA COMIC qq
Oh oh maybe you won't do it but, you know Sukitte Ii na yo? I love that one D: Going to watch this one too but fanart of Mei and Yamato would be cute too D:
Btw I love this drawing
Btw I love this drawing

subset: commoncrawl


text:
Connecticut Yankee Pedaller Inc.
Welcome to South Central Iowa's Leading Bicycle (and Trike) Shop!
"Repairer and Purveyor of Bikes, Trikes, and the Like"
906 Court Ave, Chariton, IA 50049 641-774-5557
Bicycle Service:
Staff, Shop, and CYP Travel Pics
Service and Labor Rates
Contact Us
July 2015 Hours:
We will be Closed on Saturday, July 4 in Observance of Independence Day
Sunday: Closed
Monday - Friday: 10 a.m. - 5:00 p.m.
Sat.: 9 a.m. - 3 p.m.
"...or by appointment beyond the posted hours."
Chariton Hospitality
Customer Gallery- Coming Soon!
New website coming! Meanwhile, enjoy our current site!
Recumbent Clothing Now in Stock
(Recumbent-Friendly Pockets and Comfort from Bend-It Cycling)
Expedition Shorts- $79.95
Elite Shorts- $69.95
Cycling Jerseys- $59.95 and up
2015 RAGBRAI Repair/Service Sites
Tour de Chariton Comfort Ride with Jan Mickelson
Photo Courtesy of Bill Howes, Chariton Newspapers
Thanks to Carpenter's Hall, Pipers, The Chuckwagon, & Chariton Newspapers for Your Assistance!
Now in Stock in Atomic Orange, Eon Green, Lava Red!
New Products from TerraTrike Now Here:
New Product in Stock
Commute out of the Weather (doors coming)- with Electric Assist
Organic Transit Elf!
Now Stocking The Most Comfortable Upright Bike, Ever- "Period"
Electra Townie!
Here For 2015!
Comfortable, Foldable in 10 seconds, 26" Rear Wheel, Only $2290!
HP Velotechnik Scorpion plus 20 (in stock) and plus 26
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Trident Trikes - Now In Stock!
Spike 1 Spike 2 Stowaway I Stowaway II Transport 20 & 26 Chameleon
CYP Inc. / 906 Court Ave., Chariton, IA 50049


text:
I don't understand why anyone would be anti-cementic. Personally, I like bridges, roads, and schools.
The Italians stole it borrowed it off a truck from the Latins.
Cunts. Now you've even driven the Jew away and historically that's been next to impossible.
Following the example of Italians is your attempt at making sense?
Is it July already?


text:
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Pastors Argue 'Snake Handling' Is Their Religious Right
Most states have outlawed snake handing, even for religious services.
'Serpent-Handling' Pastor Killed by Snake - Just Like Dad Was
A West Virginia pastor died after his rattlesnake bite him at outdoor ritual.
Serpent Sensation: Name that Snake(s)
Nameless snake to get new moniker through social media.
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text:
Albert Jeremiah Beveridge, 1862-1927
Albert Jeremiah Beveridge, 1862-1927 Senator of Indiana. Half-length portrait, seated at desk, facing right. ... show more
Albert Jeremiah Beveridge, 1862-1927
1 photographic print.
Senator of Indiana. Half-length portrait, seated at desk, facing right.
- D4728 U.S. Copyright Office.
- Title and other information transcribed from caption card and item.
- Frances Benjamin Johnston Collection (Library of Congress).
- No. 1; No. 28889.
- Formerly in Biog. File.
- Caption card tracings: Photog. I; BI; Photogr. index; B.F.; Shelf.
- Johnston (Frances Benjamin) Collection
- Photographic prints--1900.
- Portrait photographs--1900.
Johnston, Frances Benjamin, 1864-1952. Portraits
Johnston, Frances Benjamin, 1864-1952, photographer
- Album: All photos
- Heart Unheart
- Comment
Added by AncientFaces


text:
Could someone post a complete list of the heralds that Galactus has had in chronological order if possible?
Q: List of Heralds
This edit will also create new pages on Comic Vine for:Beware, you are proposing to add brand new pages to the wiki along with your edits. Make sure this is what you intended. This will likely increase the time it takes for your changes to go live.
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Fleeing India: What Will Make Clinical Trials Flood BackContributor: Ghida Harfouche
Posted: 8/11/2014
India's clinical trial industry has seen it all. In less than 10 years, the country has grown to become a leading destination for clinical trials, attracting studies from multinational pharma companies and contract research organizations. This however is no longer the case as the once skyrocket growth has now come to a brutal end. If India's clinical trial industry is to pick up again, a major restructuring of its regulatory system will have to take place. Full Article »
Experiences with IRT- An Interview with CTS manager Michael PompeyContributor: Michael Pompey
Posted: 10/22/2013
Ahead of the Clinical Trial Supply Europe event, Pharma IQ presents interviews filmed live at last year's CTS event. In this interview Michael Pompey talks about the daily challenges he faces as a clinical trial supply manager at Sandoz and he discusses his experience with IRT. Full Video »
Epigenetic Cancer Therapies and the TOPAS Trial- An Interview with Hella KohlhofContributor: Gerald Clarke
Posted: 10/2/2013
For Dr Hella Kohlhof, the study of epigenetics was not love at first sight, however the potential it posesses eventually won her over. Now Dr Kohlhof is Manager of Translational Pharmacology at 4SC AG and is applying epigenetic knowledge in a phase 1 first-in-man trial. She talks to us about what role epigentics plays in cancer and how new therapies are taking advantage of epigenetic mechanisms. Full Podcast »
Seems Everyone Is Building Clinical Data Repositories, Now How Are We Going To Use Them?Contributor: Robert Musterer
Posted: 2/19/2015
Whether you call it a clinical data repository (CDR) or a clinical data warehouse (CDW); it seems everyone (oh, all right - at least a lot of companies) are either building, or planning to build one. Most of these companies have grand notions of bringing together data from a wide variety of sources to be able to glean new insights. However the big unanswered questions are; just how are these insights to be gleaned, and who will be doing the searching to glean these insights? Full Column »
In the build up to Trial Master Files Europe 2015, Claire Mooney, TMF Lead - Process and Quality, Quintiles and Pharma IQ take a closer look at how a modern day global contract research organisation (CMO) is approaching eTMF and assess the top 5 benefits and burdens of utilising the CMO's electronic trial master files. Full Whitepaper »
Trial Master File
Hotel Alimara Barcelona , Barcelona, Spain
September 7- 9, 2015
11th International Conference Intelligent Compound Libraries 2015
October 13- 15, 2015
Clinical Trial Supply Europe
Brussels, Belgium
January 19- 20, 2016


text:
With Instructables you can share what you make with the world and tap into an ever-growing community of creative experts.
share what you made with text, photos, video, and files
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Quickly shorten a dog leashby rsmaudsley
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Most Read
Transport News
Malaysian taxi drivers are gaining international recognition - or rather, infamy - for their bad attitude.
They ramp up headcount as COE supply grows but experienced staff are hard to find. -ST
Car Reviews
Besides being required by law, why is it so important to belt up in the backseat of a car?
Backseat passengers who do not buckle up can hurt themselves and others in the car during a crash....
The story this week of more than 20 people who paid good money to a parallel importer for cars they will probably never get is a familiar one. -ST
With the car quota system, sharing vehicles will lead to greater demand for road space. -ST
It was a chaotic and dramatic scene along Pasir Ris Drive 3 after a taxi crashed into another car in front.


text:
Dr. Louis Olegario is an anesthesiologist in Greensburg, who manages patient pain levels before, during, and after surgical procedures.
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We invite you to write a review about your experience with Dr. Olegario.
Find potential causes and treatment options with the MD.com Symptom Checker.
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"Pomp, pageantry, and adventure" --Houston Chronicle
"Opulent … and glitteringly picturesque" --The Washington Post
As seen on HBO
Ben Cross (Chariots of Fire) and Amy Irving (Crossing Delancey) star in this haunting love story set against the spectacular sweep of battle, treachery, and intrigue in the India of the British Raj.
Born to British parents but raised as Indian, Ashton Pelham-Martyn returns to India as a young military officer, where he fights both local unrest and the cultural prejudices of society. Struggling to reconcile his place in two different worlds, he finds happiness with his childhood sweetheart, Indian princess Anjuli--but she is promised to marry another man. From the snowcapped peaks of the Himalayas to the fabled palaces of Bhithor, M.M. Kaye's evocative novel is brought to life in this stunning and lavish production.
The all-star cast also features Christopher Lee (The Lord of the Rings), Omar Sharif (Lawrence of Arabia), Rupert Everett (The Importance of Being Earnest), and Sir John Gielgud (Gandhi).
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I've watched this series three or four times, and it still captivates me. Not five stars because over time I've come to see how lame Amy Irving's character is and what a... Read morePublished 20 days ago by Leila Sequim
A great story with beautiful scenery and talented cast. Enjoyed every episode.Published 1 month ago by Francis King
An unbelievably excellent adaptation of M. M. Kaye's novel! Love that subtitles are included as you don't miss anything that way. Read morePublished 1 month ago by Norma J. Singer
Disc 1 is defective, sound and picture are not synchronized. At times there is no sound and half a picture. I will be returning this itemPublished 2 months ago by anna butler
Good movie. I had not read anything about this film and was expecting a "broader" view of India and Indian life as opposed to the focus on one major character. Read morePublished 3 months ago by Edward T Freels


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Mexican Veal
|Veal cutlets
|6 , cut 1/2 inch thick
|1 , beaten
|Dry breadcrumbs
|2⁄3 Cup (10.67 tbs)
|1⁄4 Cup (4 tbs)
|Canned tomatoes
|1 Pound (1 Can)
|1 1⁄2 Teaspoon
|1⁄4 Teaspoon
|Squash zucchini
|3 Medium, sliced
1. Pour egg into a shallow dish
2. Spread breadcrumbs on a plate.
3. To bread the cutlets, dip them in beaten egg and then drop in the plate of bread crumbs to coat both sides evenly.
4. In a large skillet, heat the shortening.
5. When the shortening is hot, arrange the breaded cutlets in the pan.
6. Fry for 4-5 minutes on each side until evenly browned.
7. Drain off the excess fat from the pan.
8. Add tomatoes and seasonings to the cutlets in the skillet.
9. Cover skillet and reduce the flame to low.
10. Simmer cutlets for 30 minutes.
11. Add the sliced zucchini to the skillet and continue simmering for another 30 minutes until the meat is fork tender.
12. Arrange cutlet on a serving plate.
13. Spoon the tomato and zucchini sauce on top
14. Serve hot.


text:
Is This the Hottest Building in Lincoln Park? A 2-Bedroom at 1335 W. Altgeld
This 2-bedroom loft in the Piano Factory Lofts at 1335 W. Altgeld in Lincoln Park just came on the market.
I couldn't find information as to when the 15-unit building was converted into lofts.
This corner unit has north and west exposures with 10 foot timber ceilings, exposed brick and antique doors.
Both bedrooms appear to have windows which is rare for lofts.
The kitchen has white cabinets and stainless steel appliances.
The listing says there are 2 "brand new" baths.
The loft has the features that buyers look for including central air, washer/dryer in the unit and covered parking.
This is the 4th unit that has come on the market in this building in the past 2 months.
1 of those has already closed and 2 others went under contract almost immediately.
- #2F: 1/1 listed in March 2015 for $335,000. Just sold for $297,500
- #1C: 2/2 listed in April 2015 for $450,o00. Under contract within days.
- #2A: 2/1.5 listed in April 2015 for $450,000. Under contract within days.
- #1B: 2/2 that just came on the market for $459,000
26% of the building has been listed in just the past 2 months.
Is this the hottest building in Lincoln Park?
I guess lofts aren't dead after all.
Kathleen Knorr at Coldwell Banker has the listing. See the pictures here.
Unit #1B: 2 bedrooms, 2 baths, no square footage listed
- Sold in May 2005 for $400,000 (per Redfin as the CCRD was "down" this weekend)
- Sold in August 2008 for $360,000 (per Redfin)
- Currently listed for $459,000
- Assessments of $364 a month
- Taxes of $5604
- Central Air
- Washer/Dryer in the unit
- Covered parking included
- Bedroom #1: 20×16
- Bedroom #2: 12×11


text:
NEWARK – NJPAC's Alternate Routes Series presents its annual fiery weekend of Latin jazz with three performances from Friday, October 30 through Sunday, November 1, 2009.
Recreation & Lifestyle
Model Railroad Club Announces Annual Show Dates, Advance Ticket Availability
by staff report • • 0 Comments
UNION—The Model Railroad Club, Inc. will put discount advance tickets for its 2009 annual light and sound show and open house on sale Saturday, Oct. 17.
Liberty Hall Museum Hosts Events in November
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UNION— Liberty Hall Museum at Kean University will host several activities for children and visitors of all ages throughout November.
"…Where The 'STREETZ' Are Paved…"
by rocky-o • • 0 Comments
For some, the 'culture' of 'rap' and 'hip-hop' connects in a way that 'hymns' or 'rock-n-roll' can connect for others.
High School Plans Comedy Fundraiser
by staff report • • 0 Comments
SCOTCH PLAINS—Union Catholic Regional High School's Parent Guild will present a Night of Comedy featuring three nationally-known comics on Friday, Nov. 13 at 7 p.m. at Union Catholic High School 1600 Martine Avenue, Scotch Plains.
Halloween Trick Or Treat Coupons Benefit Easter Seals
by staff report • • 0 Comments
STATE – This October, Friendly Ice Cream Corporation is supporting Easter Seals Camp Friendly's through a special Halloween campaign that lets you give out free ice cream as an alternative to traditional Halloween candy.
Edison School Plans Annual Fall Fair
by staff report • • 0 Comments
EDISON—The Parents' Association at the Wardlaw-Hartridge School will host its annual Fall Fair on Saturday, Oct. 24, from 10 a.m. to 4 p.m. on campus at 1295 Inman Avenue in Edison.
AAA Offers Tips On How To Speak 'Auto Tech' To Improve Auto Repair Experience
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HAMILTON—A trip to the auto repair shop can feel like visiting a foreign country for some motorists—they do not understand the language and are worried about being taken advantage of by the locals.
Festival To Feature Over 50 Fine Artists
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WOODBRIDGE – The Parker Press Park in Woodbridge will again be transformed into a fine art and craft gallery on Saturday, Oct. 10. The second annual BarronFest, a free-to-the-public juried fine arts and crafts festival, will feature over 50 talented local artisans.
Community Calendar
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Diabetes Screening • Oct. 9 from 2-4 p.m. – The Linden Board of Health will conduct a diabetes detection screening for Linden residents at the Council Chambers in City Hall, 301 N. Wood Ave. For info, call 1-908-474-8410.


text:
Big Shot: OpenShot Video Editor Version 1.0 Released
Video clip editors have been in short supply under Linux. Jonathan Thomas is now trying to fill that gap with the first stable version of the OpenShot Video Editor.
As in many of the applications of the craft, a video editor works on a timeline in OpenShot with clips arranged on multiple tracks, edits them and adds effects. A preview then shows what's been accomplished.
Compared with its biggest competitor, Kdenlive, OpenShot provides fewer functions, but the user interface is thereby better organized to benefit new users.
The first stable version is now available after two years or so in development and a number of pre-versions. Apart from bugfixes the new version includes some new functions, among them 28 new transitions and 29 titles that self-adjust to the aspect ratio of the image. The time format now includes the frame number instead of the millisecond.
User interface themes provide variety; a selection four is included, with one specific to smaller screens with smaller icons. Screen functions were improved and simplified, including a "New Project" toolbar to replace "Open Project." Window resizing is persisted across window launches and transitions snap to the nearest clip or play-head.
OpenShot processes standard and also HD material, including HDV 720p in 24 frames per second common to movie quality video.
Download of OpenShot to try it before installation is available from the project page as an AV Linux 3.0 LiveDVD. Burn the ISO image to a DVD and boot off it. Complete packages are currently only for Ubuntu, so users of other distros need to rely on a source code tarball.
Issue 177/2015
Buy this issue as a PDF
NoScript Flaw
Mozilla's script blocker add-on could be putting malware sites on the whitelist.
RIP SSLv3
The Internet community officially banishes the notoriously unsafe Secure Sockets Layer protocol.
Mate 1.1 Arrives
Popular desktop environment continues the Gnome 2 legacy – with new support for the Gnome 3 toolkit.
US Government Requires HTTPS
The Obama White House has issued a memorandum telling all US government agencies they must use HTTPS for all websites and web communication.
Mozilla Signs Firefox Add-Ons
New program will dial up security for the Firefox browser.
Fedora 22 Arrives
Red Hat's community distro embraces the cloud.
Code.org and College Board Team Reach Out for Talented High School Coders
New partnership will bring more and better CS training to US schools
A Peek Inside TeslaCrypt Ransomware
Criminals offer online help over Tor network
Mumblehard Still Spams
Sophisticated malware is still present on Joomla and WordPress sites around the world.
Launchpad Gets Git
Future versions of Ubuntu's code service will support the popular Git version control system used with Linux and other open source projects.


text: My daughter and I have just returned from a 4 night stay at this delightful little hotel. Based centrally in the town, it is close to shops, cafes, restaurants and beach. The apartment was lovely and spacious and great facilities if you were self catering. Spotlessly clean and the most friendly and helpful staff. The roof top pool was an... More


text: Great place to grab Breakfast or Lunch....offering a wide variety of eclectic Sandwiches, Wraps, Salads Gourmet Coffees and Desserts, along with more standard items for the less daring. Everything seemed to be prepared in house and the counter help was friendly and very helpful. Plan to return the next time we visit Vero Beach.


text:
Parles vous Francois? Sprache de Deutche?
View Single Post
January 2 2013, 12:26 AM
Mr. Laser Beam
Fleet Admiral
Location: The visitor's bullpen
Re: Parles vous Francois? Sprache de Deutche?
I used to know a fair whack of the German language but I don't remember a lot of it now.
Right now I'm like Korben Dallas in
The Fifth Element
- I only speak two languages, English and bad English.
"Pitching is simple -- cheese for the kitchen and a yakker for the kudo." - Dennis Eckersley
Mr. Laser Beam
View Public Profile
Send a private message to Mr. Laser Beam
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text:
ASUS Radeon HD 7970 Crossfire review -
DX11: Battlefield 3
DX11: Battlefield 3
One of the biggest game releases of 2011 is Battlefield 3, a combat immersive game that is about to blow you from your socks. We'll take this title and have a look at DX11 performance with the newest graphics cards.
With the plot set in 2014, SSgt Blackburn leads a five-man squad on a mission to locate, find and safely return a US squad investigating a possible chemical weapons site, whose last known position was a market controlled by a hostile militia called the PLR. Blackburn and his squad is later sent to Tehran to apprehend a high-value target named Al-Bashir. While investigating an underground vault in a local bank, Blackburn and his team learn that the PLR had access to Russian portable nuclear devices, and that two of the devices are missing.
All test runs have enabled:
- Ultra mode
- 4xMSAAAA enabled
- 16x AF enabled
- HBAO enabled
- Level: Operation Swordbreaker
We test at Ultra quality mode, should your graphics card have sever issues running in this configuration, by all means select a lower quality level or disable MSAA, 4xA MSAA will cost you almost a third to half your framerate. The chart above, shows various cards in 1920x1200.
We use a run that is located in the Operation Swordbreaker level, have a peek where we are recording:
Above the level we use to measure game performance. This is the operation SwordBreaker level- a generic recording, not specific to this graphics card.
Our Battlefield 3 DirectX 11 benchmark run, here we are in DX11 mode with Ultra settings. This is the Operation Swordbreaker level where there is a good balance in-between graphics card GPU load and processor utilization, making this an excellent level to test GPU performance in. There will be levels that are a tiny bit more stringent, there will be levels and sections way more easy. We think this level is the best representation of the game engine though.
In this review we look at the new ASUS Radeon R9 380 STRIX. Armed with a silent cooler this Tonga GPU based product bring you mainstream gaming at a price of roughly 200 USD - With 2GB of grap...
ASUS Radeon R7-370 STRIX Review
We review the AMD Radeon R7-370 series. That means 1080P gaming will become in reach at an affordable 149 USD price level. Based on older architecture this product now is reinjected as the 370 series...
ASUS Radeon R9-290X Matrix review
In this review we will benchmark and test the ASUS Radeon R9-290X Matrix Platinum edition. This Radeon R9-290X has been overhauled from A to Z. Yeah, the GPU might have remained in-tact, however the g...
ASUS Radeon R9-290 DirectCU II OC review
We review the ASUS Radeon R9 290 DirectCU II OC edition. Ever since AMD released their Hawaii based GPUs they have been popular. The reference cards might run hot, but the custom cooled editions from...


text:
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Hylands teething tablets! Magic!
I second the Hylands! Also, mine have never liked traditional teethers. They have gone for rubber anything (pacifiers, bulb syringes, spatulas), damp washcloths, metal (spoons and such), wooden toys and leather at various times,but best of all is a finger!
Good luck mama! Teething is hard, but we've all made it through right? The teeth will come, and you will sleep again!
Teething is so hard! Amber necklaces are amazing! Hazelaid.com is very affordable. I didn't learn about them until I had my second baby, and really wish I did with my first. The Hylands tablets are great too, tho. I couldn't imagine teething without them!
I think teething is a tough task. I will suggest you to try Hylands teething tablets. I hope you will find it useful.
hope it gets better!!
~ I am obsessed with car seat safety and advice on the best car seats!
Love you all!!
Kaitlyn R.
Michelle mom to DD , DS , & lil DD and spending my days
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text:
2006 Pontiac Grand Prix Q&A
2006 Pontiac Grand Prix Question: headlights don't work
2006 Pontiac Grand Prix low beam headlights don't work. - VicA
Answer 1
It's possible that the switch is failing, and you have lo-beam headlight relay #35 and 10A fuses #3 and #4 supplying power to the lo-beams. Check the relay and fuses. It's possible that both lo-beam filaments burned out at the same time, which can result from bad battery connections. If the bulbs turn out to be the problem, check your battery connections. - Superbob
Related Items:
Bright headlights always work. This started after had to replace battery. Have replaced body control module. Have checked modules under hood. Also, when unlocking car door locks my headlights don'...
After checking fuses,relays.I replaced combination switch .Still don't have low beam headlights,would shoul I check next,and where is it located at on car?
The Power windows don't work (no power to the switch). Went looking for the fuses/circuit breakers for the power windows. Owners Manual says under instrument panel, removed plastic cover under in...
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text:
VIEWS: 0 PAGES: 21 CATEGORY: Electronics POSTED ON: 4/13/2012 Public Domain
The technology described herein generally relates to nanostructures, and more particularly relates to use of nanostructures to connect and bond adjacent layers of conductive materials.BACKGROUND There are many instances in the production and manufacture of electronic devices that a layer of material, such as present in one component, is required to be attached--often at specific locations--to a substrate, such as a wafer or die. Insuch instances, the integrity of the attachment, whether it is mechanically, thermally or electrically, can be critical for the performance of the device. Examples include: attaching or bonding a flip-chip to an underlayer (a substrate such as a die); fine-pitch chip-on-flex technology as used in LCD manufacture; and wafer-level bumping for creating electrical contacts at a fine pitch. In allsuch applications, current technologies are experiencing significant limitations, due in part to the increasing demands for miniaturization of electronic devices. use of "flip chip" technology is growing rapidly and the technology is currently used in devices such as mobile phones, MP3-players, smart cards, displays, computer peripherals. However, in terms of complexity and product cost, flip chiptechnology has drawbacks, due to the requirements of complex processes that involve bonding and connecting the flip chip to the die. These processes include solder flux coating, chip/board arranging, solder bump reflow processes, flux removal processes,underfilling, and cure processes. The techniques used in bonding and connecting flip-chips are moving towards increasingly greater numbers of I/O contacts, and finer pitches between the contacts. See, for example, "Anisotropic Conductive Film for Flipchip Applications: AnIntroduction," by Peter J. Opdahl, available at www.flipchips.com/tutorial05.html, incorporated herein by reference. As an alternative to solder bumping, anisotropic conductive film (ACF) has emerged as a lead-free, environmentally-friendl
Pages to are hidden for
"Connecting And Bonding Adjacent Layers With Nanostructures - Patent 8106517"Please download to view full document


text:
Talk:Guillain–Barré syndrome
|Skip to table of contents
Guillain–Barré syndrome is currently a good article nominee. Anyone who has not contributed significantly to (or nominated) this article may review it according to the good article criteria to decide whether or not to list it as a good article, as outlined on the nominations page.
Reviewers: To start the review process, follow this link: start review. This will create a dedicated subpage for the GA review. Save this page. (If you have already done this, and the template has not changed, try this talk page. See here for instructions.)
|This is the talk page for discussing improvements to the Guillain–Barré syndrome article.
Article policies
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|Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Guillain–Barré syndrome.
|WikiProject Medicine / Neurology
|(Rated B-class, Mid-importance)
- 1 Header
- 2 Treatment
- 3 Prognosis
- 4 Distinguishing between Gilbert and Guillain–Barré Syndromes
- 5 Why are the H1N1 vaccine cases not included in the cause section?
- 6 Guillain-Barre Syndrome Notable Cases
- 7 Classifcation
- 8 Updating
- 9 Epidemiology
- 10 Acute autonomic neuropathy
- 11 Babinski in Bickerstaff
- 12 Guillain-Barré mechanism
- 13 Another push
- 14 ref
"a result of an acute polyneuropathy"
-- I have found several sources that call this a "polyradiculopathy"
L - Landry-Guillain-Barré Syndrome (GB) or Acute Inflammatory Demyelinating Polyradiculopathy to Local Anesthetic Pharmacology pp. 387-397 By May C. M. Pian-Smith and Lisa Leffert. http://ebooks.cambridge.org/chapter.jsf?bid=CBO9780511586057&cid=CBO9780511586057A017 — Preceding unsigned comment added by Tmbirkhead (talk • contribs) 04:33, 8 January 2015 (UTC)
"These two treatments are equally effective"
No problem with this
"and a combination of the two is not significantly better than either alone."
Big problem with this
I had Guillain-Barre (and 100% recovery, thank goodness) and received both treatments. It is very important to realize that the two treatments are completely incompatible. That is, they absolutely cannot be administered simultaneously, but if administered consecutively, the end result can be superior to just using one of them (or not). With intravenous immunoglobulins (aka IVIG) you are getting other people's white blood cells, in the hope that it makes your own white blood cells behave themselves, as opposed to what they are doing (destroying your peripheral nervous system's myelin sheath). With plasmapheresis, on the other hand, (almost) all of your white blood cells are being removed from your blood, in the hope that the new white blood cells generated by your system (bone marrow) will behave themselves. Stay with me here, either you are getting a whole bunch of extra white blood cells, or you are losing a whole bunch of the white blood cells you already have. You cannot do both at the same time, don't you agree? The idea is to (a) use IVIG to shock the system into some kind of stability, although it is not a cure then (b) once stability but not cure is achieved, to use plasmapheresis to effect a cure. At least, that is what my doctors told me they were doing. And it worked. So my experience is that IVIG, followed by plasmapheresis, *is* significantly better than either alone. Not too sure what to do about providing a reference. IVIG is extremely expensive, so may not be an option in every health-care context. Plasmapheresis is, essentially, just a form of dialysis, so it is not that expensive and should be generally available. — Preceding unsigned comment added by Gsa703 (talk • contribs) 19:09, 7 October 2013 (UTC)
- Very nice that the combination worked for you. We prefer to base wikipedia on scientific research. The immunoglobulins are way smaller particles than white blood cells, so plasmapheresis of just the white blood cells (and not the plasma fluid with the ivig in it) can be done simultaneosly to ivig administration. But if you're convinced otherwise, please provide scientific sources that contradict the currently used reference. PizzaMan (♨♨) 15:22, 11 December 2014 (UTC)
This section does not appear to have rigorous references.
"Recovery usually starts after the fourth week.."
I had Guillain-Barre. My experience with my doctors was that my recovery time was a direct reflection of my time-to-diagnosis. That is, the sooner I was diagnosed, the less my recovery time. In my case, I was diagnosed in about 50 hours and had a recovery time of about 50 weeks. So one week for every hour until diagnosis (and treatment).
That said, let's talk about when recovery starts. Presumably that means when things start stabilizing. Again, I suggest that it totally depends upon how fast the patient gets to a knowledgeable physician. In my case, I think my recovery started after the second week, but that is not a reflection of Guillain-Barre, nor of the physician, but solely of how fast I noticed that I had a problem, and did something about it.
"About 80% of patients have a complete recovery.."
Where does this come from? My doctors said that 98% of patients have a recovery in which there are no long-term disabilities, such as having to use a cane, or a walker, or take medication, etc. Aside from the fact that I should probably not donate blood, I have zero effects upon my well-being from having had Guillain-Barre. — Preceding unsigned comment added by Gsa703 (talk • contribs) 19:39, 7 October 2013 (UTC)
- I've added a reference and a little bit of text based on the reference. Note that the reference doesn't support the statement of recovery starting after four weeks. As for the 98%, that's a bit optimistic. For example: "Among severely affected patients, 20% remain unable to walk 6 months after the onset of symptoms." (NEJM 2012). Unfortunately, the appendix doesn't contain the prognostic models it's supposed to when i try to download. And you're right that the onset of therapy is a prognostic factor: "Days between onset of weakness and admission, Medical Research Council sum score, and presence of facial and/or bulbar weakness were the main predictors of mechanical ventilation" (Walgaard, Ann Neurol. 2010).PizzaMan (♨♨) 15:41, 11 December 2014 (UTC)
Distinguishing between Gilbert and Guillain–Barré Syndromes[edit]
I feel that it would be a good idea to add a "not to be confused with" label at the top of the page to distinguish between Gilbert's and Guillain–Barré syndromes. The latter is often pronounced like "gillie-bear" while Gilbert's is sometimes pronounced "jill-bear" (apologies for the bad formatting), opening up the possibility of people looking at the incorrect article, so I'm going to add a tag to both articles. I leave this section open to discussion of the topic as both can be confusing to spell given their non-English etymologies. Zedtwitz (talk) 02:32, 18 February 2014 (UTC)
- I really doubt that anyone will make the confusion, because Gilbert is one name, and "Guillain-Barré" is always used together. Wikipedia:Hatnote describes the guidance. JFW | T@lk 14:25, 20 February 2014 (UTC)
Why are the H1N1 vaccine cases not included in the cause section?[edit]
I recently added info and links from a 2009 study of H1N1 influenza vaccines and had it removed citing a link supposedly 'fisking' the ones I provided. Why are recent studies not included in this article? It's currently dated to be archaic (1977?, really?). Editing is still new to me, so please help modify the cause section to include recent info.
- I removed the sources because they did not meet the criteria outlined in WP:MEDRS; we prefer secondary sources in high-quality publications. I am particularly worried by the reference to MCT lawyers - this is a no-win no-fee outfit, and their content is not peer reviewed. JFW | T@lk 19:26, 30 June 2014 (UTC)
Guillain-Barre Syndrome Notable Cases[edit]
This help request has been answered. If you need more help, you can user talk page, or consider visiting the Teahouse., contact the responding user(s) directly on their
|Long discussion about notable patients
|The following is a closed debate. Please do not modify it.
If the article was authored by the subject of the article and the references take us to the website of said author, is it considered a Primary Source? Regards, Aloha27 talk 17:44, 20 October 2014 (UTC)
This is an encyclopedia, not People magazine. We should not restrict ourselves to celebrities – Hollywood actors, sports stars, musicians, TV anchors, a few politicians – which at present comprise all the Guillain-Barre case reports on Wiki. The only case of real, enduring interest in that list is US President Roosevelt. Your list satisfies a longing to worship celebrities, but that is not enough. After all, we are working under the heading "Notable Cases," not "Notable People."
"Notable Cases" should include case reports that actually teach something about the disease – information not found elsewhere – and case reports that illuminate how the rare nature of this disease creates an unforseen struggle within the health-care system. This would serve the public interest. Medical Rights (talk) 04:35, 19 October 2014 (UTC)
Re Ms. Sil's Guillain-Barre Reference[edit]
■ Ms. Sil – Primary reference: The article in question was published in The Medical Post, issue 29(5):32. This journal "gives priority to doctors"; it is their stated mandate. The Medical Post doesn't typically accept patient accounts. That type of writing is left to home-style magazines and media reports; note such consumer sources have a blunting similarity with respect to GBS accounts; all sound the same apart from a change of name, job, and city. By contrast, The Medical Post accepts only articles of interest to doctors, which means that article must teach something new, even to doctors.
■ Ms. Sil – Secondary reference #1: The Saskatoon Star Phoenix newspaper reprinted Ms. Sil's entire article. Reference: What to Do When Doctor Doesn't Know Best, Star Phoenix, Lifestyle cover story, 24 September 1994.
■ Ms. Sil – Secondary reference #2: In the same edition of the Star Phoenix, in-depth editor Katheryn Warden devoted her entire column to discussing that piece. Reference: Informed Patients Involved in Medical Decisions, Star Phoenix, page C9, 24 September 1994.
■ Shortly, these secondary references will be available online. For independent verification visit a University Library, or any large Public Library, and consult their newspapers stored on micro-fiche.
■ Academic Qualifications: Ms. Sil earned an M.Sc. from the University of British Columbia in the field of Physics (Lasers and Nonlinear Optics).
■ Peer Review: The Medical Post – before publication as it does for any article – vetted at length the medical information from Ms. Sil. As did the journalist Ms. Sil collaborated with at the Star Phoenix.
■ The notable concept in Ms. Sil's article is the role reversal between doctor and patient. Many patients struggle to get diagnosed, but very few do the work themselves, with no medical training. Ms Sil applied for and obtained her own medical chart while she was in the hospital and used that chart to work alongside her doctors. She wrote notes to correct errors in her chart; these were accepted. This had the full blessing of Hospital Administration.
■ Ms. has, on her website Tuum Est, her diagnostic results for Guillain-Barre. Not just word reports, but graphs of Nerve-Conduction Velocity (EMG) tests. There are two sets of graphs, for tests done 3 weeks apart, giving a very clear picture of how the peripheral nerves demyelinate. Since the disease is rare, this would interest doctors (and med students), perhaps most in less advanced countries of the world. Medical Rights (talk) 04:35, 19 October 2014 (UTC)
Hold Wikipedia to an Academic Standard[edit]
(1) Wikipedia is an encyclopedia, and the standard should be academic. On the Guillain-Barre page, the focus should be "Notable Cases" – the section's actual title. The title is not "Notable People." Whether a person is a rock star, football coach, or politician has little to do with whether readers will absorb anything of value from the reference. Stars likely receive better medical care during the acute stage of their disease, because then MDs and nurses are under a media magnifying lens, and don't want to be skewered for mistakes or neglect. Thus media reports of "star" cases may not mirror the average patient's experience. Later on when the media report becomes a simple reference, know this: Doctors are not star-struck and neither are most people searching for medical information. An "interesting case" refers to medical interest; doctors care not a jot about the glamor level of a patient's life.
(2) Perhaps there could be three lists: / Notable Cases (Academic) / Notable People (Stars) / GBS Patients Who Published Books /
(3) JDWolff removed Ms. Sil's reference from the Guillain-Barre page on Wiki. On his personal page, JDWolff says he is a "doctor of acute medicine." If that is true (and I assume it is), then that places JDWolff in a conflict-of-interest position. Physicians as a group have a reputation for being highly sensitive to criticism – any criticism – of other doctors, of clinical skills, of hospitals. I expect JDWolff is no different. JDWolff should not be allowed to remove items that criticize health care, without a backup opinion from an objective administrator at Wiki (objective = someone not connected with health care).
(4) Recently, B.C. doctors began a campaign to increase the medical worth and accuracy of Wiki. Source: Wikipedia's Medical Errors and One Doctor's Fight to Correct Them (CBC News, 21 August 2014) at http://www.cbc.ca/news/canada/british-columbia/wikipedia-s-medical-errors-and-one-doctor-s-fight-to-correct-them-1.2743268 That news report says: "Studies have shown that, on average, at least 50 per cent (or more) of doctors use Wikipedia in their practice. Heilman says the website is an easy way for physicians to jog their memories. For medical students, Wikipedia is their second most used information source." Therefore, in the public interest Wiki has a duty on medical pages not to be star-struck, or to simplify the topic to pablum. Post updated. Medical Rights (talk) 04:35, 19 October 2014 (UTC)
Tuum Est Follows Own Motto: It Is Up To You[edit]
Tuum Est has no time for edit wars. Yesterday Tuum Est began its own list of Notable Cases with sub-titles such as: Doctors Stricken with GBS, Nurses Stricken with GBS, and Other Notable Cases. The sources are personal accounts published in peer-reviewed medical journals. Physicians, nurses, and other technical people are objective observers during the acute stage of GBS. Such people make incisive observations about symptoms, and about the journey through the health system. Physicians hold such personal accounts in esteem, saying they are highly instructive because the disease is rare. Tuum Est will include only Notable People whose disease has one or more features of medical interest. Roosevelt would be an example. Medical Rights (talk) 04:35, 19 October 2014 (UTC)
Secondary Sources are Now Online[edit]
Ms. Sil's case of Guillain-Barre is supported by secondary sources. We produce these sources which Wiki instructs are important. Tuum Est scanned the original newspaper pages to form electronic JPG or PNG images. Our small scanner size meant we had to separately scan the top and bottom half of each newspaper page. Then we had to make a single document from the two halves. The methods we tried: (a) Concatenate the images in Apple Automator and output the result as a PDF. The result, however, looked very grainy for these old newspaper pages. (b) Then we tried an HTML webpage as a container; the code has a header plus two <img> tags to vertically align the two halves of the newspaper page on a white background. This worked well. You can obtain the individual images by clicking the image on the webpage and choosing "Save As". Medical Rights (talk) 12:29, 20 October 2014 (UTC)
Here are the links to the secondary sources, plus the original Medical Post publication:
Discussion closed for archiving. JFW | T@lk 15:54, 29 October 2014 (UTC)
The classification of GBS has been revised. doi:10.1038/nrneurol.2014.138 discusses it. JFW | T@lk 12:32, 29 October 2014 (UTC)
- Epidemiology papers: doi:10.1159/000184748 (2009) and doi:10.1159/000324710 (2011); different approaches and probably both worth citing.
- Association with vaccines: doi:10.2165/00002018-200932040-00005 (2009) and doi:10.7774/cevr.2014.3.1.50 (2014). JFW | T@lk 09:10, 30 October 2014 (UTC)
- Brighton criteria were brought about by vaccine worries: doi:10.1016/j.vaccine.2010.06.003 JFW | T@lk 23:54, 30 November 2014 (UTC)
This article has needed tidying up for some time.
- ✓ Done Signs and symptoms - needs to be more detailed on the clinical distinction between subtypes
- ✓ Done Causes - currently not written; this needs to list the common infectious triggers (chlamydia, campylobacter, herpesviruses, mycoplasma)
- ✓ Done Mechanism - needs updating in general, especially with some discussion about the serological signals
- ✓ Done Diagnosis - better sourcing for the importance of each test
- ✓ Done Treatment - good sources are available, need more about the rehabilitation aspects
- ✓ Done Prognosis - recently some information added, although some more QOL information would be valuable
- ✓ Done Epidemiology -
vaccine triggers should be discussed herediscussed under "causes" instead
- ✓ Done History - good secondary sources exist for this
- ✓ Done Notable cases - should be migrated to its own subarticle
- ✓ Done Research directions - we may need to talk about eculizumab
- ✓ Done References
- ✓ Done Further reading -
should be integrated in the content; the book listed there currently is a good candidate for this section
- ✓ Done External links - should be minimalist
- doi:10.1038/nrneurol.2014.138 (2014), Nat Rev Neurol consensus group on classification
- doi:10.1038/nrneurol.2014.121 (2014), Nat Rev Neurol general review
- doi:10.1002/mus.24192 (2014), Muscle Nerve mostly about the subtypes with disialosyl antibodies (Miller Fisher syndrome, ataxic GBS and ASAN).
- doi:10.1111/jns5.12051 (2014), J Peripher Nerv Syst about HRQOL
- doi:10.1097/MOP.0b013e328365ad3f (2013), Curr Opin Pediatr GBS in children (not covered currently)
- doi:10.1016/S1474-4422(13)70215-1 (2013), Lancet Neurol axonal GBS
- doi:10.1586/1744666X.2013.811119 (2013), Expert Rev Clin Immunol infectious and noninfectious triggers
- doi:10.1111/jns5.12020 (2013), J Peripher Nerv Syst general update
- Epidemiology sources listed above
- PMID 22820829 and PMID 21912364 - review about rehabilitation
Will try to do some stuff here. Help appreciated as always. JFW | T@lk 00:00, 2 November 2014 (UTC)
- I've got that book "Guillain-Barré:From diagnosis to recovery". I'll get more info up and cite it. Let me know if/when I do that incorrectly? Regards, Aloha27 talk 13:24, 3 November 2014 (UTC)
- Review in children (in addition to Ryan2013). I have no access: doi:10.1542/pir.33-4-164 JFW | T@lk 08:43, 1 January 2015 (UTC)
Epidemiology[edit] In Western countries, the incidence (number of episodes per year) per 100,000 people has been estimated to be between 0.89 and 1.89 cases. The risk increases by 20% for every decade.[29]
My concern is that the sentence "The risk increases by 20% for every decade" could be misinterpreted to mean that the risk of GBS is increasing with every decade for the population as a whole, rather than as the age-related increase observed. The cited study says that "GBS incidence increased by 20% for every 10-year increase in age." [1]
I've not done any editing on Wikipedia, which is why I'm commenting rather than editing myself. Wikimol03 (talk) 06:02, 5 December 2014 (UTC)
- Thanks Wikimol03. I will rephrase. Always feel free to change something yourself; great articles come about because folk like yourself are BOLDly updating pages. JFW | T@lk 21:11, 6 December 2014 (UTC)
Acute autonomic neuropathy[edit]
I removed the following:
- Acute panautonomic neuropathy is the rarest variant of GBS, sometimes accompanied by encephalopathy. It is associated with a high mortality rate, owing to cardiovascular involvement, and associated dysrhythmias. Frequently occurring symptoms include impaired sweating, lack of tear formation, photophobia, dryness of nasal and oral mucosa, itching and peeling of skin, nausea, dysphagia, and constipation unrelieved by laxatives or alternating with diarrhea. Initial nonspecific symptoms of lethargy, fatigue, headache, and decreased initiative are followed by autonomic symptoms including orthostatic lightheadedness, blurring of vision, abdominal pain, diarrhea, dryness of eyes, and disturbed micturition. The most common symptoms at onset are related to orthostatic intolerance, as well as gastrointestinal and sudomotor dysfunction.[2] Parasympathetic impairment (abdominal pain, vomiting, constipation, ileus, urinary retention, dilated unreactive pupils; loss of accommodation) may also be observed.
The reason for this removal is the fact that none of the reviews (NEJM2012, NatRevNeurol2014 and others) mention it as a GBS subtype, and doi:10.1136/jnnp-2012-302833 states that inclusion is "disputed". A very recent classification system (still need to cite) by Wakerley et al does not include it (doi:10.1038/nrneurol.2014.138). I am happy to be corrected, but for now I will stick to the classifications introduced by the key sources. JFW | T@lk 22:06, 7 December 2014 (UTC)
Babinski in Bickerstaff[edit]
Thanks to user:TylerDurden8823 for the contribution. But why remove babinski reflexes from the Bickerstaff symptoms? That's not just a decreased reflex. PizzaMan (♨♨) 08:17, 12 December 2014 (UTC)
- The source I saw describing BBE did not mention Babinski at all. If you have a source for Bickerstaff that mentions Babinski sign (not a symptom but a medical sign), feel free to add it back in. I didn't think that was something a major review would gloss over and if it were really a prominent feature of BBE, I figured the Nature Review would probably have at least mentioned it once. I'm not opposed to adding it back in though if you or someone else can demonstrate it is part of BBE with a reputable source. TylerDurden8823 (talk) 13:48, 12 December 2014 (UTC)
- Recent reviews point out that hyperreflexia may occur in the early stages of all cases. I don't think Bickerstaff's is unique. JFW | T@lk 15:32, 12 December 2014 (UTC)
- So, we don't need to mention it specifically then for BBE? TylerDurden8823 (talk) 22:48, 12 December 2014 (UTC)
- Very interesting for a disease of the peripheral nervous system. And so would a babinski be, because that's typically caused by a damaged piramidal tract. But yes, in that case it should be mentioned in general then in stead of specifically with Bickerstaff. JFW, can you point us to one of those reviews? Again, TylerDurden8823, thank you for contributing to this article. PizzaMan (♨♨) 13:29, 13 December 2014 (UTC)
- So, we don't need to mention it specifically then for BBE? TylerDurden8823 (talk) 22:48, 12 December 2014 (UTC)
- Recent reviews point out that hyperreflexia may occur in the early stages of all cases. I don't think Bickerstaff's is unique. JFW | T@lk 15:32, 12 December 2014 (UTC)
- PizzaMan The finding of hyperreflexia is already mentioned in "Signs and symptoms". The NEJM2012 and NatRevNeurol2014 sources do not actually mention abnormal plantar reflexes, so perhaps that finding is unique to BBE. JFW | T@lk 20:22, 13 December 2014 (UTC)
- If we do find a good review that does specifically mention this, I have no objection to saying that Babinski is part of BBE. I just want to see verification. TylerDurden8823 (talk) 22:39, 13 December 2014 (UTC)
- PizzaMan The finding of hyperreflexia is already mentioned in "Signs and symptoms". The NEJM2012 and NatRevNeurol2014 sources do not actually mention abnormal plantar reflexes, so perhaps that finding is unique to BBE. JFW | T@lk 20:22, 13 December 2014 (UTC)
Guillain-Barré mechanism[edit]
The cited NEJM article and 15 July 2014 Nature Neurology review on Guillain-Barré by van den Berg et al. states that BOTH AMAN and AIDP are caused by antibody formation, albeit directed towards different peripheral nerve targets. AIDP is less well characterized, but involves antibodies formed against unidentified antigens of the Schwann cell itself. AMAN is caused by antibodies against GM1 and GD1a gangliosides located in the node of Ranvier. These antibodies are formed via molecular mimicry from Campylobacter lipo-oligosaccharide outer membrane. Please see Figure 2 in the cited NEJM article or Figure 2 in the Nature review.
Nature Reviews Neurology 10, 469–482 (2014) doi:10.1038/nrneurol.2014.121 Published online 15 July 2014 — Preceding unsigned comment added by 22.214.171.124 (talk) 15:57, 2 May 2015 (UTC)
- The NEJM review uses guarded language ("autoantibodies may bind to myelin antigens") and in the text itself does not mention the antibodies nor their possible epitopes. The van den Berg review similarly is vague on this (apart from discussing anti-GM2 in CMV infections). I will have a look at the wording. Presumably someone has tried to demonstrate the actual presence of IgG on the myelin sheath, but the reviews don't cite this evidence. Thanks for bringing this up. JFW | T@lk 21:40, 23 June 2015 (UTC)
Another push[edit]
So, having some time available, I might just be able to finish the work on this and get it nominated for GA:
- ✓ Done Address the point of the anonymous editor in the previous section
- ✓ Done Finish the "neurophysiology" section with sources listed above (Uncini in particular) - a neurology colleague has explained the key points of NCS/EMG
- ✓ Done "Citation needed" in "clinical subtypes" with regards to Bickerstaff
- ✓ Done Complete the "rehabilitation" section, replacing the content that is based on primary sources.
- ✓ Done In "prognosis", incorporate the HRQL discussion from doi:10.1111/jns5.12051
- ✓ Done In "prognosis", address the "citation needed" tags
Help appreciated as always. JFW | T@lk 20:54, 22 June 2015 (UTC)
possible references[edit]
- review [1][2][3]
- systematic [4] (page)
- books [5] (page)
- position statements [6][7][8][9][10]
- Cochrane reviews [11][12][13][14]
- American Association of Neuromuscular & Electrodiagnostic Medicine [15]
I would also recommend this image in symptoms section as half of those affected experience cranial nerve involvement perhaps these can help--Ozzie10aaaa (talk) 22:18, 25 June 2015 (UTC)
- @Ozzie10aaaa: I wasn't planning on adding more sources, and you will find that I've referenced the relevant Cochrane reviews. JFW | T@lk 18:26, 26 June 2015 (UTC)
- ^ http://www.karger.com/Article/FullText/324710
- ^ Suarez, G. A.; Fealey, R. D.; Camilleri, M.; Low, P. A. (1 September 1994). "Idiopathic autonomic neuropathy: Clinical, neurophysiologie, and follow-up studies on 27 patients". Neurology 44 (9): 1675–1675. doi:10.1212/WNL.44.9.1675. PMID 7936295.


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Damage resulting from the Oklahoma City bomb
Swofford, Jason L
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Early on the morning of April 19,1995, terrorists detonated a large amount of high explosives on NW 5th Street, just north of the Alfred P. Murrah Federal Building in Oklahoma City, Oklahoma. A rental truck contained approximately 5000 pounds of ammonium nitrate and fuel oil. Several buildings surrounding ground zero suffered structural damage, and many buildings suffered severe window breakage. The explosion killed 168 people and injured more than 600 others in proximity and away from ground zero. Flying glass shards resulting from fractured windows caused the majority of the injuries. The bombing of the Alfred P. Murrah Federal Building marked the largest terrorist act experienced in the United States. This document reports on the damage to structures caused by the blast, and more specifically the performance of various window glass types and window constructions.
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Kukla's Korner Hockey
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"This validates us as a franchise in the NHL again," Lowe said in a private moment on Saturday, shortly before the Oilers took another step toward their impossible dream. "It wasn't the hardcore [Oilers] fans but I think the casual fans and sponsors thought the Oilers can never win. "What's important is what's happening within our own market. The fans were still supporting the team but I think that without this kind of run, we'd have trouble holding their attention. There's a lot made about the revenue but it's the consumer confidence and the reinvestment in the branding that's important to us."more
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The awards presentations and public reception for the national juried art show "Arts In Harmony" at the Sherburne County Government Center will be held Sunday from 1 to 3:30 p.m. This show has more than 200 pieces selected from over 1,000 entrants including about a half-dozen local/area arti...Read More
Elk River Area Arts Alliance
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> instrumental in the establishment and continuation of the parish in
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The video was kind of plain due to the scenes being long and having no sounds but overall it was pretty good.
This is scary creepy friggin shit! I must admit, in the anime, the Pokemon Ash catches for Oak all end in reserves where they are watched and studied, but this is a more adult version of 'what if' with all the excess Pokemon. Considering though, it seems more fit for the horror theme, not comedy. Wasn't very funny at all. But what do I know? I'm a 25 year old gamer... my extensive education wound up with me never getting my own job or home...
I know a lot of people didn't find it funny haha! I'm just a sick twisted bitch I consider it a comedy-horror.
Hahaha!! Incredible! Well deserved best of the day! I don't know if 12 year old me understood the consequences of choosing Charmander and contributing to the pile of Bulbasaurs.
Thanks ryan-san-chan-sempai-kun! I remember your pokemon parodys, they're funny as hell.
This was well done, had some funny moments perhaps... but damn, it is CREEPY!! >.<
"Lavender Town" alone is creepy (spent too much time on CreepyPasta), and the stuff in the video to compliment it, wow, damn, I don't know why it says 'Parody - Comedy' here.
Still, it was indeed well done. ^^
Haha its a comedy because I have a very fucked up sense of humor- everything in the video was very funny to me, but I can definitely see how people can find it creepy and scary and not funny.
This is the creepiest shit I have ever watched. I feel violated.
I think I've terrorized all of newgrounds.


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O'Neill Rumour Dress - Girls'View Larger Image
- Detail Images
The O'Neill Girls' Rumour Dress gives you a fresh, grownup appearance for your class photo op. Paired with some tights and stylish boots you'll be voted class trendsetter in no time.
- Tank-top style dress with asymmetrical hem provides a flattering, pretty appearance
- Elastic waist, spaghetti straps, and tie back offer a classy, back-to-school look
- Polyester fabric feels smooth and lightweight against your skin and dries quickly
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Shopping For And Buying Vehicles Online Archive
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LIVE From NY Auto Lab, Car Topic Call-In; Saturday June 27, 2015
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