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General information can be had through some fine sites such as:
Some things to do before you go.
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Recipe by Anna
"I hate ginger, but I love this sweet, tangy roll! It's great as a dessert, but also perfect for brunches or tea parties."
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1 1/4 cups
all-purpose flour
1 1/4 teaspoons
baking soda
1 teaspoon
ground ginger
1 teaspoon
ground cinnamon
1 dash
ground nutmeg
1 teaspoon
ground allspice
1/2 cup
warm water
1/3 cup
white sugar
1/3 cup
1/3 cup
melted butter
1/4 cup
confectioners' sugar
1 cup
sweetened whipped cream
I make a ginger roll cake very similar to this one - but this recipe has way better cake! It's easier to roll the cake up in the parchment paper/towel while hot, then allow to cool. Unroll to ice and it rolls back up in a snap without breaking :-) I also use a honey cream icing sometimes instead of whipped cream (2tbsp honey, 8oz unsalted butter and 1/3 cup icing sugar blended). Yum!
1 Rating
* Percent Daily Values are based on a 2,000 calorie diet.
Ginger and Cream Cake Roll
Serving Size: 1/8 of a recipe
Servings Per Recipe: 8
Amount Per Serving
Calories: 257
Calories from Fat: 92
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New blog entries coming soon! - 12/26/12
New blog entries are coming soon, so check back often!
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Everything tagged
Latest from The Spokesman-Review
County OKs settlement in Creach death
July 10, 2013 in City on Page A5 Spokane County commissioners on Tuesday voted to approve a $2 million settlement with the family of Wayne Scott Creach, a Spokane Valley nursery owner and pastor shot to death in … 10
County settles Creach case
June 22, 2013 in City on Page A1 The family of a Spokane Valley pastor shot to death after a confrontation with a deputy sheriff in 2010 will receive $2 million. The settlement was reached Friday after U.S. … 154
Creach civil case can move to trial
Feb. 12, 2013 in City on Page A1 A civil suit against a sheriff's deputy in the 2010 shooting death of a Spokane Valley pastor has enough evidence to warrant a jury trial, a federal judge has ruled. … 86
Sheriff's office releases Creach shooting investigation
July 7, 2011 in News The Spokane County Sheriff's Office posted a redacted version of the investigation into the shooting of Wayne Scott Creach by Deputy Brian Hirzel online. 6
Deputy cleared in Creach shooting
June 23, 2011 in City on Page A1 The Spokane County sheriff's deputy who shot a 74-year-old Spokane Valley pastor last year will face no disciplinary action over the fatal encounter. Deputy Brian Hirzel followed all departmental policies … 23
Pastor's family seeks limits on unmarked police cars
May 11, 2011 in City, News The family of a Spokane Valley pastor killed in a police confrontation outside his home called on Sheriff Ozzie Knezovich today to voluntarily prohibit the parking of unmarked patrol cars … 27
Unmarked police cars targeted
May 11, 2011 in City on Page A5 Two lawmakers from Spokane Valley want to bar law enforcement officers from parking unmarked police cars on private property for routine matters. The legislation, sponsored by Republican state Reps. Matt … 13
Panels find Creach shooting reasonable
April 28, 2011 in City on Page A1 Spokane County Sheriff's Deputy Brian Hirzel acted "in a reasonable manner" when he fatally shot a 74-year-old pastor last summer in Spokane Valley, two departmental reviews have concluded. "Deputy Brian … 20
Sheriff's panels say pastor's shooting was 'reasonable'
April 27, 2011 in City, News Spokane County Sheriff's Deputy Brian Hirzel acted "in a reasonable manner" when he fatally shot a 74-year-old pastor last summer in Spokane Valley, two departmental reviews have concluded. 44
Mayor Towey: City's health is good
April 14, 2011 in Washington Voices on Page V1 Spokane Valley Mayor Tom Towey gave the first of four planned State of the City speeches Monday night to a crowd of about 50 people in Valley Fourth Memorial Church. … 3
Deputy won't face charges in shooting
Jan. 22, 2011 in City on Page A1 A Spokane County Sheriff's Office deputy won't face criminal charges in the shooting death of a 74-year-old Spokane Valley pastor, a decision Prosecutor Steve Tucker says came down to this … 50
Deputy won't be charged in shooting death of pastor
Jan. 21, 2011 in City, News Spokane County Prosecutor Steve Tucker has decided not to file criminal charges against the deputy who shot 74-year-old pastor Wayne Scott Creach during a confrontation last August in Spokane Valley. 171
Creach interred near childhood home in Oklahoma
Sept. 3, 2010 in City on Page A7 Wayne Scott Creach was laid to rest Thursday on a hillside cemetery in a plot that overlooks the tiny Oklahoma town and nearby farm where the pastor and Spokane Valley … 73
Deputy's approved vacation stalls interview about shooting
Sept. 2, 2010 in City on Page A1 The interview that could explain why a deputy shot and killed a Spokane Valley pastor will come Friday morning – after the deputy returns from a weeklong vacation approved by … 93
Son offers insight into pastor's fatal encounter
Sept. 1, 2010 in City on Page A1 Spokane Valley pastor Wayne Scott Creach and his wife had a prearranged system for when the business owner encountered trespassers on the couple's sprawling nursery and greenhouse complex in Spokane … 79
Valley officer kills pastor at nursery
Aug. 27, 2010 in City on Page A1 A pastor and widely recognized Spokane Valley businessman, concerned that a prowler was on his property late Wednesday, got out of bed, apparently armed himself with a pistol and headed … 47


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The recurrence rate of anti-SSA/Ro associated congenital heart block (CHB) is 17%. Reversal of 3rd degree block has never been achieved. Based on potential reduction of maternal autoantibody titers as well as fetal inflammatory responses, IVIG was evaluated as a preventative therapy for CHB.
A multicenter open-label study based on Simon's 2-stage optimal design was initiated. Enrollment criteria included: maternal anti-SSA/Ro antibody, a previous child with CHB/rash, </= 20 mg prednisone, < 12 weeks pregnant. IVIG (400mg/kg) was given every 3 weeks from 12 to 24 weeks of gestation. The primary outcome was the development of 2nd or 3rd degree CHB.
Twenty mothers completed the IVIG protocol before reaching the pre-determined stopping rule of three cases of advanced CHB. CHB was detected at 19, 20 and 25 weeks; none followed an abnormal PR interval. One of these mothers had two previous children with CHB. One child without CHB developed a transient rash consistent with neonatal lupus. Sixteen children had no manifestations of neonatal lupus at birth. No significant changes in maternal antibody titers to SSA/Ro, SSB/La, or Ro52 were detected over the course of therapy or at delivery. There were no safety issues.
IVIG at doses consistent with replacement does not prevent the recurrence of CHB or reduce maternal antibody titers. Having established safety with this protocol and feasibility of patient enrollment, subsequent preventative studies may be considered, perhaps to include higher doses of IVIG.
One of the strongest clinical associations with autoantibodies directed to components of the SSA/Ro-SSB/La ribonucleoprotein complex is the development of congenital heart block (CHB) in an offspring, an alarming prospect facing 2% of mothers with these reactivities [1, 2]. The risk is 10-fold higher in women who have had a previously affected child [3–5]. CHB carries a significant mortality (20–30%, primarily fetal/ neonatal) and morbidity (67% require permanent pacing before adulthood) [5, 6]. Evidence is emerging that in addition to conduction disease, 10–15% of affected offspring will have a life-threatening cardiomyopathy [7, 8]. One of the most disturbing observations to emerge is the rapidity of disease progression, with advanced heart block detected within a week of normal sinus rhythm (NSR) [2]. Biomarkers such as prolongation of the fetal Doppler mechanical PR interval have not convincingly demonstrated utility in predicting advanced block [2]. Consistent with the fibrotic replacement of the atrioventricular node (AV) observed in autopsy studies from fetuses dying with CHB, reversal of third degree block has never been achieved [2, 9]. Current prophylactic and treatment strategies for CHB include maternal steroids, plasmapheresis, sympathomimetics, and in utero cardiac pacing [10]. None have significantly altered mortality. Accordingly, strategies aimed at preventing disease before immutable scarring ensues, assume high priority. Although it is disappointing that animal models have not fulfilled "Koch's postulates" assuring an effect of the antibody per se, this is likely due to the fact that antibodies are necessary but insufficient. Our approach to prevention considered the necessity of maternal antibody as well as consequent fetal factors in the cascade to pathogenesis.
Intravenous gamma globulin (IVIG) has been of benefit in a variety of immune-mediated and inflammatory diseases. Rationale for its use in CHB is based on our working hypothesis of the pathogenesis of disease. Tissue injury in the fetus is presumed to depend on FcγRn-mediated transplacental passage of maternal IgG autoantibodies [11]. Anti-SSA/Ro-SSB/La antibodies, by binding to translocated antigen on the surface of apoptotic cardiocytes generated during remodeling of the conduction system and surrounding tissue, may inhibit the normal physiologic removal of these cells [12, 13]. Uncleared opsonized apoptotic cardiocytes may be subsequently efferocytosed by infiltrating macrophages with release of pro-inflammatory and profibrosing cytokines which transdifferentiate cardiac fibroblasts to a scarring phenotype [13, 14]. This scenario supports the consideration of prophylactic IVIG based on two presumed mechanisms of efficacy. The first exploits the saturation of FcγRn by IVIG. This should decrease fetal exposure to anti-SSA/Ro-SSB/La by accelerating IgG catabolism in the maternal circulation and decreasing placental transport [15, 16]. The second exploits the attenuation of anti-inflammatory responses by increasing the macrophage expression of FcγRIIB [17]. This would represent a downstream effect in the targeted organ.
Precedent for the use of IVIG is the encouraging report of only 1 recurrent case of CHB in 8 mothers with previously affected children [18] and murine data demonstrating a decrease in placental transport of human anti-SSA/Ro-SSB/La antibodies following IVIG [19]. Accordingly, a prospective US based multi-center open-label trial to determine the efficacy and safety of IVIG on the prevention of CHB in women with anti-SSA/Ro antibodies and a previous child with neonatal lupus was initiated. Treatment comprised IVIG at 400 mg/kg, dosed every 3 weeks from 12 to 24 weeks of gestation. The primary outcome was the development of 2nd or 3rd degree CHB.
Subjects entered this prospective multi-center open label clinical trial between January 2007 and January 2009. A total of 17 women from centers across the US signed consent forms approved by the Institutional Review Board at the site of their infusion. Four mothers provided consent as participants of the Research Registry for Neonatal Lupus to release medical records and send blood specimens but received drug as prescribed by their treating physicians who elected to follow and adhere to the study protocol. Of the 21 women enrolled, there was one screen failure due to a spontaneous miscarriage at 9 weeks prior to initiation of the study protocol.
Enrollment required all of the following inclusion criteria 1) documentation of anti-SSA/Ro and/or anti-SSB/La antibodies 2) a previous child with one of the following: a) CHB (any degree) documented by EKG if live birth and/or echocardiogram and/or histology if fetal demise; b) characteristic NL rash confirmed by photograph revealing annular lesions, dermatology note, and/or biopsy; c) CHB and rash; 3) current intrauterine pregnancy ≤12 wk with normal heart beat and structure. A patient was excluded for any of the following: 1) current dose of prednisone > 20mg or any dose of dexamethasone 2) level of Ig A below normal values for laboratory 3) presence of any structural abnormalities of the fetal heart that could cause CHB, ie, L-transposition of the great arteries, AV septal defect, or heterotaxias.
Mothers could be clinically asymptomatic or have symptoms of a rheumatic disease. Rheumatologic disease was classified on the basis of case report forms filled out by the participating rheumatologists, obstetricians and cardiologists performing the echocardiograms and verified by telephone interviews and review of medical records when available (by J.P.B., C.L. and P.M.I). The following categories were assigned 1) asymptomatic if a patient denied any clinical symptoms that would be consistent with systemic lupus erythematosus (SLE) or Sjogren's syndrome (SS); 2) undifferentiated autoimmune syndrome (UAS) if insufficient criteria for SLE or SS; 3) SLE if 4 criteria of the American College of Rheumatology were satisfied [20]; 4) possible, probable, or definite SS if a patient had at least dry eyes and dry mouth or only 1 symptom plus evidence of objective criteria in addition to autoantibodies as per the European Classification [21]; or 5) SLE and SS if criteria for both were met.
The trial was designed as an open-label trial employing Simon's 2-stage optimal design [22] to allow for early stopping due to absence of treatment efficacy. The first stage required 19 subjects. If 3 or more mothers had children with 2nd or 3rd degree CHB, then the study would be terminated after the first stage. If this did not occur, an additional 35 mothers would be enrolled in the second stage for a total of 54 subjects. At the end of trial, the treatment would be considered efficacious if fewer than 6 mothers of 54 had a child with advanced CHB. With this design, the study had 90% power to conclude that IVIG is efficacious if the true recurrence rate with the treatment is 5%. In addition, the probability of rejecting the treatment for further study is 95% if the true recurrence rate is 19% [3, 5]. It should be noted that the enrollment goal for the first stage was exceeded by two patients because of initial concern there might be a screen failure due to miscarriage (which occurred in one case).
IVIG infusions of 400mg/kg were given over 3–4 hrs at 12 wks, 15 wks, 18 wks, 21 wks and 24 wks of gestation. Blood samples were obtained before each infusion and at 28 wks, 34 wks and delivery (including cord blood). Fetal echocardiograms were performed weekly between 16 and 26 weeks of gestation and every two weeks thereafter until 34 weeks in accord with the protocol of PRIDE [2]. The studies were recorded on VHS videotape or DVD/optical disk by the patient's pediatric cardiologist or obstetrician. The image copies were sent to the core fetal echocardiographic laboratory where the studies were reread by D.M.F.
The primary outcome was 2nd or 3rd degree AV block. The secondary outcomes were 1) sustained 1st degree AV block as defined by a prolonged mechanical PR interval [PR >150 msec, i.e., > normal mean +3 SD] [23] that did not progress to more advanced forms of AV block throughout the study and subsequently confirmed by EKG at birth 2) transiently prolonged mechanical PR interval 3) any sign of myocardial injury such as reduced contractility, tricuspid regurgitation or effusions, without change in cardiac rate or rhythm 4) echocardiographic densities consistent with endocardial fibroelastosis (EFE) confirmed postnatally 5) fetal death not related to cardiac dysfunction 6) rash consistent with neonatal lupus 7) prematurity defined as gestational age at birth < 37 weeks 8) birth weight less than 10% in the context of gestational age 9) abnormal fluid collection in the fetus consistent with hydrops.
Samples were aliquoted and maintained at −70°C. For each subject, serial samples obtained as per the protocol were stored until the pregnancy was completed. The evaluation of antibody titers and total IgG in all maternal samples and corresponding cord bloods was completed on the same day. Titers of antibodies to anti-SSA/Ro and/or anti-SSB/La were done by ELISA (Diamedix Corp, Miami, FL). In this commercial test, the cutoff for normal has been established at 19 EU for both SSA/Ro and SSB/La. Titers of antibodies to Ro52 were evaluated by ELISA using recombinant Ro52 as previously described [24]. IgG levels were determined by radial immunodiffusion using the BN ProSpec® System, Dade Behring-Siemens Health Care.
Changes from baseline in maternal antibody titers measured at specific time points during pregnancy were evaluated with the paired t-test. A two sided P-value < 0.05 was considered statistically significant.
The demographic characteristics of the patients including health and antibody status and obstetrical history are summarized in Table 1. Twenty mothers have completed IVIG treatments with 19 having given birth. The majority of enrollees were Caucasian (80%). The maternal diagnoses at the time of enrollment in the study were as follows: 3 (15%) were classified as asymptomatic, 7 (35%) as UAS, 5 (25%) SS, 4 (20%) SLE with secondary SS, and 1 patient with Rheumatoid Arthritis and secondary SS. Sixteen (80%) of the patients had antibodies to SSB/La in addition to SSA/Ro. Eighteen (90%) of the enrolled women had a prior pregnancy complicated by CHB (1 with two CHB children) and two had a previous child with a neonatal lupus rash. In 8 (40%) of the mothers, the prior pregnancy complicated by CHB ended in a fetal demise. Four (20%) of the patients were on prednisone <20 mg/day (mean dose 9.5 mg/day; range 8–10 mg/day) during the study and 2 mothers were taking hydroxychloroquine 400 mg/day throughout pregnancy.
Twenty mothers have completed the IVIG infusions (1 woman only received 4 doses of IVIG) and 19 mothers have given birth. Seventeen fetuses have completed the serial echocardiograms with normal PR intervals (Figure 1) and normal birth EKGs. Of these 17, one neonate presented with a rash consistent with neonatal lupus several days after birth.
Three fetuses were diagnosed with advanced block. The first case of CHB was detected at 19 weeks of gestation. The patient had received 3 doses of IVIG at weeks 12, 15 and 18. The fetal echocardiogram at detection revealed third degree block with mild tricuspid regurgitation and no hydrops. The previous fetal echocardiogram at 17 weeks of gestation revealed a normal PR interval and no signs of valvular dysfunction. Once CHB was diagnosed, the patient began dexamethasone at 4mg/day for 10 days with no effect on the heart rhythm. The patient delivered at 37 weeks of gestation. The neonate was small for gestational age and received a permanent pacemaker at birth. In addition, the postnatal echocardiogram showed a moderate secundum atrial septal defect corrected by surgical closure at 2 months of age.
The second fetus with CHB was diagnosed at 20 weeks of gestation after 3 doses of IVIG. Routine weekly fetal echocardiograms were done as per protocol from 16 weeks of gestation and each showed a normal PR interval. Two weeks after the third infusion the fetal echocardiogram revealed 2nd degree Wenckebach with occasional dropped beats. The mother was prescribed one oral dose of 4 mg of dexamethasone and received a total of 2g/kg IVIG plus intravenous dexamethasone 4mg/day for 2 days. However, 2nd degree CHB progressed to 3rd degree CHB within 2 days. There was no evidence of tricuspid regurgitation, effusions or hydropic changes. The baby was born at 37 weeks of gestation and was small for gestational age. The postnatal echocardiogram confirmed 3rd degree CHB with normal systolic function. A pacemaker was implanted at 7 days of age.
A third CHB case was detected at 25 weeks of gestation after the mother received 4 IVIG infusions. Previous PR intervals during pregnancy had been normal up to 22 weeks; however the mother missed the 23 and 24 week fetal echocardiograms and third degree block was detected at 25 weeks of gestation. After discussion with her physician, the patient decided to take only one dose of 4 mg dexamethasone. The fetal echocardiogram performed during her last evaluation at 30 weeks of gestation, showed no signs of hydrops, TR regurgitation or effusions. The ventricular rates remain above 96 beats per minute.
Two of the mothers whose pregnancies were complicated by CHB were classified as SLE with secondary SS at the time of enrollment and one of them as UAS. Two of the mothers had, in addition to anti-SSA/Ro, anti-SSB/La antibodies and each had anti-Ro52 antibodies. One of these mothers had two previous children with CHB. The other two had one prior pregnancy complicated by CHB, one of which ended in fetal demise. The study was stopped at this point according with the pre-determined rule.
Maternal sera obtained from mothers completing the study were available for evaluation of anti-SSA/Ro-SSB/La titers. Antibody titers assessed before every IVIG infusion, and at 28 wks, 34 wks and delivery were compared with values obtained at baseline. As shown in Figure 2, treatment with IVIG did not significantly alter the titers of anti-SSA/Ro, anti-Ro52, or anti-SSB/La antibodies (P>0.05 for all comparisons).
There were no changes in maternal blood pressure, severe headaches, rashes, fever or any other adverse effects related to the infusions. There were no serious adverse events. Neonatal growth data are presented in Table 2. Weight, height, and head circumference were derived from gestational age -specific growth curves to correct for prematurity when necessary. Four (21%) of the newborns, two with CHB and two healthy, were small for gestational age (<10%) and 3 (16%) were born prematurely (<37 weeks of gestation). One of the mothers with a healthy baby small for gestational age and two of the mothers with premature babies were taking prednisone during pregnancy.
This study recruited 21 mothers, 20 of whom received prophylactic IVIG to prevent autoimmune associated CHB. The study was discontinued after reaching the stopping rule of detecting 3 CHB cases in the first 19 patients enrolled. There were no significant changes in the titers of antibodies to SSA/Ro or SSB/La done by commercial ELISA in a central laboratory or in the titer of antibodies to Ro52. No safety issues were raised in this pilot study. In parallel with the enrollment of the PITCH study, a European study was initiated in December 2004. The treatment protocol was identical to that utilized in PITCH. That study was terminated after 3 cases of CHB were identified following enrollment of 15 mothers who had previously affected children with CHB (unpublished data, with permission of Dr. Munther Khamashta, U.K.). Combining data generated from the two studies in which the prior pregnancy was CHB, not rash, there were 6 cases of recurrent CHB in 33 mothers (15 UK and 18 US) which is consistent with the recently reported recurrence rate of 17.4% [4] and confirms that IVIG at 400mg/kg dosed every three weeks from 12 gestational weeks is not effective in reducing the incidence of recurrent disease.
IVIG is approved by the FDA for primary immunodeficiency, idiopathic thrombocytopenic purpura, Kawasaki disease, B cell-chronic lymphocytic leukemia with hypogammaglobulinemia, pediatric HIV infection, and allogenic bone marrow transplant in adults [25]. Several mechanisms have been posited to account for the effects of IVIG in autoantibody-mediated disorders, but none satisfactorily explains all clinical situations. Immunomodulatory properties attributed to IVIG include downregulation by antiidiotypic antibodies and effects on receptors for cytokines and complement [26]. Administration of IVIG in a murine model [27] inhibits autoantibody-mediated thrombocytopenia by inducing inhibitory FcγRIIB receptors on macrophages. Recent data support that a structure within the Fc portion of IVIG, a N-linked glycan terminating in sialic acid in a 2,6 linkage to the penultimate galactose, is a requisite for activity [28]. The 2,6-sialylated Fc interacts with a lectin identified as SIGN-R1, expressed on marginal zone macrophages to initiate an anti-inflammatory pathway that ultimately modifies the ability of effector macrophages to trigger activation FcγRs in response to autoantibody deposition. One pathway by which this may be accomplished is through enhanced expression of the inhibitory FcR, FcγRIIB, on these effector macrophages. Although the applicability of these findings to the pathogenesis of CHB is unknown, it is notable that the fully processed glycan is found in only 1–3% of IgG in IVIG. Further experimental evidence from murine models demonstrates that maternal administration of IVIG significantly inhibits the transplacental passage of maternal anti-SSA/Ro-SSB/La antibodies and decreases the level of pathogenic antibody in both the maternal and fetal circulation in fetal/neonatal alloimmune thrombocytopenia [19, 27]. In addition, a highly emphasized explanation unifying the beneficial action of IVIG is accelerated catabolism of IgG which is mediated by saturation of FcγRn receptors [15, 16].
Accordingly, intravenous IgG (IVIG) was considered a promising candidate for the prevention of CHB based on several potential mechanisms, the first two relate to lowering or even eliminating maternal antibody in the fetal circulation (maternal perspective): 1) increased catabolism of maternal antibody; 2) decreased placental transport of maternal antibody. Unknown however is the threshold level of antibody needed to cause injury and whether IVIG can effectively lower the level below the threshold needed to bind apoptotic cells and trigger an inflammatory/fibrosing sequence. The third consideration is an effect of IVIG transported into the fetal circulation where it might act to upregulate surface expression of the inhibitory FcγRIIB receptors on fetal macrophages thereby decreasing secretion of proinflammatory and profibrosing cytokines (fetal perspective). Accordingly, modulation of inhibitory signaling could be a potent therapeutic strategy for attenuating autoantibody-triggered inflammatory diseases. Highly speculative would be an anti-apoptotic effect of IVIG, which would certainly be relevant to the pathogenesis of CHB, in which there is evidence that apoptosis of cardiocytes provides an essential link between antibody and fibrosis [29].
The decision to dose the IVIG at 400mg/kg was based on safety, efficacy and cost issues. The replacement dose of IVIG is generally considered to be between 300 and 500mg/kg. Consistent with the serum half life of IgG, this dosing is repeated every 3–4 weeks to maintain a protective serum level [30]. It is unknown to what extent and when IVIG might decrease placental transport of the autoantibodies since it is acknowledged that antibody transport across the human placenta is minimal at 12 weeks of gestation. In addition, the dose was based on body weight of the mother but clearly the effect was not necessarily intended to achieve a lowering of the mother's total autoantibody burden. It was also hypothesized that this dose might achieve an anti-inflammatory effect in the fetus which would support the lower dose if based on the weight of the fetus, not the mother. The Finnish study, which was the only published work on preventive IVIG in CHB, comprised only 2 doses of 1g/kg [18], thus the cumulative doses used herein were identical.
A potential reason for the absence of observed efficacy relates to underdosing of the IVIG. Anti-inflammatory doses of IVIG have been reported in the range of 1–3 gm/kg body weight [30]. The absence of a change in maternal antibody titers could be a reflection of the low dose. Precedent for IVIG lowering of antibody titers as a biomarker of effect in humans is the report of serologic (decreased antibody) and clinical remission in patients with bullous pemphigus treated with IVIG [31]. Whether a significant decrease in antibody titer can be employed as a reliable biomarker of drug coverage has not been established. Precedent for the use of higher doses and presumed safety during pregnancy are studies on anti-phospholipid associated fetal loss and fetal alloimmune thrombocytopenia [32, 33].
A clear limitation of the study is the open label design. The decision against randomization was made based on several assumptions. The recurrence rate was estimated at 19% based on available publications at the time of study design [3,5]. After discussion among the co-investigators, it was decided that a clinically meaningful outcome of therapy would be at least a 50% decrease in the predicted recurrence rate. Based on power calculations, if the improvement from 19% to 10% was the case, 261 mothers with a previous CHB child per group would be required to complete a randomized control study. Even if IVIG could decrease the recurrence rate to 5%, it would require 97 mothers per group. Given the 2% frequency of CHB in anti-SSA/Ro positive mothers unselected for prior disease and the average yearly enrollment of the RRNL at 2 patients per month, it was deemed highly unlikely these enrollment goals could be achieved. Indeed, the current U.S. study took 2 years to achieve enrollment for the first phase of our study, and the European study required 4 years to enroll 15 patients. Furthermore, the likelihood that all patients would agree to randomization knowing a potentially effective therapy was being studied was deemed exceedingly rare.
In summary, this study employing Simon's optimal design showed that IVIG at 400mg/kg on a triweekly schedule from 12 weeks to 24 weeks of gestation is ineffective as a prevention of CHB in pregnancies at risk of recurrence. This finding was corroborated by the European study which used an identical protocol. However, the results support the feasibility of recruitment of high risk patients and the safety of IVIG and thus consideration might be given to higher anti-inflammatory doses.
We thank the members of the independent Advisory Board for this study: Joan Merrill, M.D; Ware Branch, M.D.; and Bonnie Bermas, M.D. We also thank Amy Lawless for the help preparing the manuscript.
This work was funded by the Alliance for Lupus Research and NIH, Contract NO1-AR-4-2220 (Research Registry for Neonatal Lupus). Clinical trial registration information-URL: http://www.clinicaltrials.gov. Unique identifier: NCT00460928
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's Canada Institute for Scientific and Technical Information in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Recipe by genalynne
"Delicious take on traditional pesto with a great creamy texture. Perfect with fusilli, bow ties, or hot baked French bread. Serve over grilled chicken too. DELICIOUS!"
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2 cups
chopped broccoli florets
2 cups
chopped fresh basil
1/4 cup
extra-virgin olive oil
1/4 cup
shaved Parmesan cheese
1/4 cup
pine nuts
6 cloves
garlic, peeled
2 tablespoons
vegetable broth, or more if needed
1 pinch
cayenne pepper
salt and ground black pepper to taste
Delicious.. the creamy texture is wonderful. I used the florets and stems of a whole broccoli since it was going to pureed anyway... cheaper. Now I need to figure out how not to eat all of it as a snack.. would be a nice chip dip or even a spoonful on top of hot soup
Yummy! I used walnuts because it is what I had. Great way to use broccoli stalks!
6 Ratings
Both broccoli and traditional basil pesto are among my favorite foods, and this recipe made me feel like I'd gone to heaven. I've eaten it on pasta, spread as a layer on salmon and baked/broiled, and just straight out of the food processor because it's so darn good. I didn't have broth, so I just adjusted the oil to get the consistency I wanted. Simple and delicious.
It was not creamy at all, way too dry and clumpy and had no delicious taste to it. I had to add jarred Alfredo sauce to the mixture to make it somewhat edible!
My new favorite pasta sauce! :)
* Percent Daily Values are based on a 2,000 calorie diet.
Broccoli Pesto
Serving Size: 1/8 of a recipe
Servings Per Recipe: 8
Amount Per Serving
** Calories: 112
** Calories from Fat: 90
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See how to make pesto with peppery, full-flavored arugula instead of basil.


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I'm running the WSO2 Stratos VMware image, and I have it to the point where it's running, I've got the browser open, it's at my internal deployment of WSO2, and I've created an account for myself. The problem is, the VM isn't networked to anything, so when it tells me it sent an email to my account and would I please validate it, I can't validate it because it never actually sent an email. I thought maybe there'd be a local mail server on the Linux guest, but I couldn't find one.
Am I missing something? Do I even need to validate the account? I can't seem to access any of the Stratos services, and I suspect that the account validation has something to do with that.


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920Re: [engineeringcivil] All purpose worksheet
Expand Messages
- Jan 1, 2009
excel sheet is very usefull....thanks..
--- On Thu, 1/1/09, ajmal atif <ajmalatif@...> wrote:
From: ajmal atif <ajmalatif@...>
Subject: Re: [engineeringcivil] All purpose worksheet
To: email@example.com
Date: Thursday, 1 January, 2009, 3:31 PMHappy new year ,with new wishesHappy new year with peace all in the worldHappy new year with respecting for all human body in the worldat end Happy new year with best wishes for the best peoplethanksAjmal AtifProvincial engineer with MoE-USAID/CDP Bearing PointKhost AfghanistanCell Phone:0093-70020491 3 & 0093-774144707Email:ajmal. atif@gmail. com,ajmalatif@ rocketmail. com
--- On Wed, 12/31/08, naresh kumar <nareshdce_431@ yahoo.co. in> wrote:
From: naresh kumar <nareshdce_431@ yahoo.co. in>
Subject: Re: [engineeringcivil] All purpose worksheet
To: engineeringcivil@ yahoogroups. com
Date: Wednesday, December 31, 2008, 11:15 AM
hi...thanks for this conversions sheet.
--- On Mon, 29/12/08, sadaf noor ahmed <ssadaf_12@yahoo. com> wrote:
From: sadaf noor ahmed <ssadaf_12@yahoo. com>
Subject: [engineeringcivil] All purpose worksheet
To: "engineer civil" <engineeringcivil@ yahoogroups. com>
Date: Monday, 29 December, 2008, 12:29 PM
Sadaf Noor Ahmed
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Telcos to NTC: No minimum Net standards for now, let's measure speed privately — Newsbytes.ph Carlos Nazareno, Newsbytes.ph, InterAksyon.com · Sunday, July 5, 2015 | 1:12 am
Chinese website invites employers to bid on university graduates Xinhua · Sunday, July 5, 2015 | 12:46 am
Autodesk expands 3D printing portfolio, partnerships InterAksyon.com · Wednesday, June 24, 2015 | 12:34 pm
APP SOUND | Music handpan opens limitless possibilities, say creators Reuters video, InterAksyon.com · Monday, June 29, 2015 | 4:13 pm
GADGET REVIEW | Acer Liquid Z520 Iñigo V. Jordana, InterAksyon.com · Friday, June 26, 2015 | 7:39 pm
Telcos to NTC: No minimum Net standards for now, let's measure speed privately -- Newsbytes.ph July 5, 2015 | 1:12 am | Carlos Nazareno, Newsbytes.ph, InterAksyon.com ISPs made known their stand to the National Telecommunications Commission (NTC) that they do not wish the regulatory body to make publicly known the measurement results of individual Internet connection metrics. READ MORE
ISPs made known their stand to the National Telecommunications Commission (NTC) that they do not wish the regulatory body to make publicly known the measurement results of individual Internet connection metrics.
A Chinese university has launched a website that profiles its graduates and asks employers to bid to employ them.
A wave of Silicon Valley-style disruption is hitting the food industry.
Russian lawmakers Friday passed a bill allowing people to force Internet search engines to remove links to data about them, overriding objections from the country's largest search provider.
Near the popular Hotel Habana Libre in Cuba's capital, a gaggle of young people on cellphones, tablets and laptops log onto the new Wi-Fi hotspot — a small milestone in one of the least connected countries.
Google 'campuses' give tech startups room to flourish
In a nod to its humble beginning in the garage of a Silicon Valley house, Google is building "campuses" around the world intended as fertile ground where entrepreneurs can flourish.
INTERNET SCAM | Nigeria returns 10,000 euros to online fraud victim
Nigeria's anti-graft agency said Thursday it had returned 10,000 euros to a French man who thought he met a beautiful Nigerian woman online willing to move to France… only to find out it was a scam.
Turkey restricts Facebook in schools -- report
Turkey has restricted students from posting pictures and opinions about school life on Facebook, Twitter and other social media, local media said Thursday.
Xiaomi semi-annual sales fall, putting full-year goal in doubt
China's top smartphone maker Xiaomi Inc on Thursday reported semi-annual sales that for the first time were lower than the previous six months, jeopardising its full-year target and hinting at a slowdown in its mainstay domestic market.
Former US federal agent pleads guilty in Silk Road case
A former federal agent pleaded guilty Wednesday to stealing Bitcoins while working undercover on a US government investigation of Silk Road, and to soliciting payment from the online black market's operator.
GADGET REVIEW | Acer Liquid Z520
The Z520 is the latest Android phone under the Acer Liquid Series catered for those who seek both budget and quality.
GADGET REVIEW | Lenovo A7000
The A7000 delivers elite-level performance comparable to the 2GB RAM variant of the ASUS Zenfone 2.
Bluetooth speakers for the wireless digital lifestyle
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Autodesk expands 3D printing portfolio, partnerships Wednesday, June 24, 2015 | 12:34 pm
Oracle extends cloud offerings, looks to compete with Amazon.com Tuesday, June 23, 2015 | 1:44 am
Oracle sales, profit miss estimates; shares fall Thursday, June 18, 2015 | 4:28 pm
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APP SOUND | Music handpan opens limitless possibilities, say creators Monday, June 29, 2015 | 4:13 pm
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VIDEO | Cockroach robot uses shell to overcome obstacles Wednesday, June 24, 2015 | 11:39 pm
VIDEO | Apple bows to Taylor Swift Tuesday, June 23, 2015 | 5:33 pm


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Zabil.cz's Appearances
3,233 Plays / 22 Likes / 3 Comments
My 2012 showreel+ More details
7,165 Plays / 41 Likes / 9 Comments
This video is a 2012 season edit of Jirka Volak from Czech Republic. Share, download, like and comment this vid with good vibez in your soul! Now sit comfortably, play in HD in a full screen mode…+ More details
Road Gap Session 2012 / Erlebachova Bouda - trailer01:27
94 Plays / 0 Likes / 0 Comments
Browse Videos
Here are all of the videos that Zabil.cz has uploaded to Vimeo. Appearances are videos that Zabil.cz has been credited in by others.


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You can now invite anyone to meet at your favorite Starbucks.
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34 year old man | San Jose, CA, USA | Seeking women 25-35 within 60 miles of Gilroy, CA
No, I don't have Facebook, Twitter, or anything else...
I love snowboarding, wild pig hunting, scuba diving in WARM water, flying small planes (I work full-time, but I am a student pilot), target shooting, fishing, wine tasting, beer tasting, hiking and taking my dog to the beach. I consider myself to be a nice guy, but please don't mistake kindness for weakness. ;-) I'm a kind-type A. Match Questions: How would your closest friends describe you? A nice guy, outgoing, funny, loyal, resolute, fit, motivated and assertive. What accomplishments are you most proud of? My military service, career, training, experience and education. What are you grateful for? My family, my health, my friends, my dog and my career. What type of person are you hoping to attract? A woman with similar values. How would you describe your social life? Normal. What types of things make you laugh out loud? Good comedy; people who are brutally honest about things. Non PC comments. What are you looking for in a relationship? Loyalty, trust, and companionship. Someone who isn't easily offended. What are the things in life you're most passionate about? Spending time with family and friends, my health, my dog, my career, flying, snowboarding, politics, our Country, travel and experiencing new adventures. Good luck on here!
Coffee and conversation , Cooking , Dining out , Fishing/Hunting , Gardening/Landscaping , Movies/Videos , Music and concerts , Exploring new areas , Nightclubs/Dancing , Playing sports , Political interests , Wine tasting
Baseball, Bowling, Cycling, Martial arts, Other types of exercise, Soccer, Walking / Hiking, Weights / Machines
I exercise 5 or more times per week.
I have Dogs
I have a Frenchie. He's the coolest dog ever and has been a trooper. He's had over $10K worth of surgeries to correct genetic-related health problems, but he is worth every penny and would do it again and again!
My house; Philz Coffee; Carmel, CA; Monterey Bay; London, England; Seoul, Korea; All Hawaiian Islands; New York; Cancun y Playa Del Carmen, MX; Cabo San Lucas y San Jose Del Cabo, MX; South Padre Island, Texas; Oregon; DC; Tampa and Miami, Key West.
Hawai`i Pacific University, Honolulu, HI
My house, my truck, my dog, great food, strong drinks, the beach, sunshine, warm weather, classic comedies, coffee, guns, and so on...
Snowboarding, scuba diving, flying small planes, baseball games, concerts, going to the beach, going out to eat, barbecuing hanging out at my house. I used to model in Asia and I did some fitness modeling a while back here in the U.S. for fun.
I don't read much outside of work, so I don't have any interesting last reads or favorite books to talk about . My last reads were work related laws, policies and procedures. Pretty boring...
Z{{Cta}} {{#if HasMoreInfo}} ?{{CtaSecondary}} {{/if}}
|What he is looking for
|6'0" (182cms)
|5'0" (152cms) to 6'1" (185cms)
|Body type:
|Athletic and toned
|Slender, Athletic and toned
|Black, Blue, Brown, Grey, Green, Hazel
|Dark brown
|Auburn / Red, Black, Light brown, Dark brown, Blonde, Platinum
|No Way
|No Way
|Social Drinker
|Social Drinker
|Political / Govt / Civil Service / Military
|Administrative / Secretarial, Artistic / Creative / Performance, Executive / Management, Financial / Accounting / Real Estate, Labor / Construction, Legal, Medical / Dental / Veterinary / Fitness, Political / Govt / Civil Service / Military, Retail / Food services, Retired, Sales / Marketing, Self-Employed / Entrepreneur, Student, Education / Teacher / Professor, Technical / Science / Computers / Engineering, Travel / Hospitality / Transportation, Other profession, Nonprofit / Volunteer / Activist, Law enforcement / Security / Military, Fashion / Model / Beauty, Architecture / Interior design
I'm currently working in the San Francisco and Monterey Bay areas.
|$100,001 to $150,000
|$50,001 to $75,000, $75,001 to $100,000, $100,001 to $150,000, $150,001+
|Never Married, Widow / Widower, Currently Separated, Divorced
|Have kids:
|Wants kids:
|Definitely, Someday
|Native American, White / Caucasian, Other
NATIONALITY: 100% PURE BRED AMERICAN! ETHNICITY: Dad's Side-English. Mom's Side-Austrian, German, Yugoslavian and 1/36 Native American.
|Christian / Protestant
|Christian / Catholic, Christian / Protestant, Christian / Other
I grew up in church every Sunday as a child...
|English, Spanish
|Bachelors degree
|Associates degree, Bachelors degree, Graduate degree, PhD / Post Doctoral


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Member Since
Oct. 2013
Cooking Level
Cooking Interests
Stir Frying, Slow Cooking, Asian, Mexican, Indian, Italian, Southern, Healthy, Dessert, Kids, Quick & Easy, Gourmet
Walking, Reading Books, Music
Profile Link
Something about the grill's heat brings out the best flavor in the simplest chicken recipe.
We have over 700 dessert recipes just for summer fun.
Delicious recipes, party ideas, and cooking tips! Get a year of Allrecipes magazine for $7.99!


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EY ITEM Club
Outlook for Financial Services Spring 2015
Forecast for Banking
"Despite the rise in UK banks' income and assets in 2014, lending to companies and households remained subdued. The picture looks brighter for 2015, but the jury is out on whether faster economic growth — underpinned by low energy prices and rising real incomes — will do enough to support the growth in bank revenues and margins that investors are hoping for."
Omar Ali
Partner, UK Banking & Capital Markets
Read Omar's full banking viewpoint
Omar Ali
UK Banking
& Capital
Despite the rise in UK banks' income and assets in 2014, lending to companies and households remained subdued. The picture looks brighter for 2015, but the jury is out on whether faster economic growth — underpinned by low energy prices and rising real incomes — will do enough to support the growth in bank revenues and margins that investors are hoping for. ↓ [... more]
A permanent change
The contraction in real incomes since 2008 means that even rising consumption is unlikely to trigger anything more than a modest recovery in household borrowing. And, while business lending is predicted to grow for the first time in six years, the figures from 2014 show that both corporates and SMEs have not just dropped alternative forms of financing in favour of borrowing from the banks. With bond and equity issuance looking to keep trending up, it may be that the recent long– term bank lending drought permanently changed behaviour.
With demand remaining subdued in many traditional activities, banks will need to continue to invest in new, differentiated products and services to ensure growth. But they will also need to keep an eye on challengers. There's definitely scope for more challenger brands and services, especially in particular pockets of the market, such as financial technology and peer–to–peer lending. We expect another 5 to 10 companies will make it over the line and into the market in 2015, which should make for a dynamic year as new players and old jostle for position.
Regulatory demands
Against this backdrop, the Competition and Markets Authority review of personal current accounts and SME banking services is a tough ask. And it won't be made any easier by the moving pieces introduced by some of the major regulatory reforms. Both the introduction of the Senior Managers Regime and discussions with the regulator on ring-fencing plans have the potential to force rethinks about the shape of the industry this year.
Stability is still elusive
To truly focus on driving renewed growth and returns, the industry needs a return to a more stable and certain environment. But at the moment, thanks to uncertainty surrounding the Eurozone economy, the outcome of the UK General Election and a possible subsequent referendum on the UK's EU membership, this scenario still looks some way off.
Download the report as a printable PDF 2.1Mb, February 2015
Download the report as an interactive, animated PDF 7.4Mb, February 2015×
Banking highlights:
The value of banks' assets and loans stabilized in 2014 after three years of decline. The strength of the UK economy should see the sector's performance continue to strengthen from 2015 onwards. But the economy will remain a long way from a credit boom.
- Net mortgage lending continued to run at subdued levels in 2014, rising by only 2.2% on the 2013 level to £1.12t.
- Consumer credit saw the fastest rate of growth in 2014 compared with other categories of household borrowing and is expected to rise at an average rate of just over 4% from 2015 to 2018.
- 2014 was another year of decline for net business lending, continuing a trend that began in 2008.
- The proportion of SMEs using only bank loans, bank overdrafts or credit cards declined from 29% to 20% between 2011 and the first half of 2014.


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Surprise! Evangeline Lilly is 7 months pregnant, debuts cute baby bump
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The Holiday Inn Auburn is the perfect location for your Finger Lakes wedding reception, rehearsal dinners and bridal showers. All events are attended to with that personal and professional touch.
We like to pamper our everyday guests, but we love to spoil our brides-to-be.
Everyday we strive to provide the very best possible quality of food, service and room arrangements for your specific event. We are a full-service banquet facility.
On the scenic campus of Syracuse University, the Sheraton offers the finest accommodations in Central New York.
There's no better location for a fairy tale wedding. A 150 year old restored Irish-styled stone castle, a 8 acres of beautiful grounds. A wide variety of menus are offered and the service is superb.
Phoebe's Restaurant can accommodate private parties of 15 to 150 people.
Our private dining room is the perfect setting for your rehearsal dinner. We can accommodate gatherings up to 110 people.
Casa Grande, our new banquet hall, is now serving all of your wedding, banquet, shower, or meeting needs.
At the American Foundry, your special event is our special passion. From our warm and caring staff, to our outstanding menu offerings, no detail is overlooked.
Having a wedding at the Bostwick House Bed & Breakfast gives you that intimate setting, relaxed whether formal or informal and on the grounds of an historic property just minutes from Downtown Ithaca.
Have a most memorable reception in the Stanley lobby! It's the perfect setting for an elegant event for up to 180 people.
Amazing Grace Bed and Breakfast is also available for a spectacular and unique wedding and/or reception venue. We have availability to host up to 300 to as many as 1000 guests.
Central NY's finest hotel offers wedding facilities to meet all your needs. The Grande ballroom for up to 300 people or the Garden Grille for 160 people.
Our the shores of Cayuga Lake, the Ithaca Yacht Club is the perfect solution for waterfront ceremonies, receptions or rehearsal dinners!! Available from April-October the Yacht Club can host tented events for up to 200 people or indoor events for 80 and is one of the only waterfront venues in the area.
The Landmark Theatre is available for a wide range of activities ranging from main stage shows, weddings and receptions, meetings, proms, corporate parties, fundraisers, and more.
In the Bellevue Ballroom, stately fireplaces at each end reveal the craftsmanship of the master brick mason. Classic furnishings welcome you in a cozy embrace.
Daniele at Valley View is Utica, NY's most elegant banquets and special events hosting facility. We are the ideal setting for all types of special events - weddings.
The Hotel Syracuse has been serving our community for over 75 years. Banquet accommodations include the Hotel Lobby and three separate and distinct ballrooms.
At The Farmers' Museum, the Louis C. Jones Center provides an ideal setting for wedding receptions of all styles
When it comes to weddings, we devote one-of-a-kind service to this once-in-a-lifetime event. From the floral arrangements and the cake to memorable farewells, we make your planning easy.
Theater Mack is a romantic wedding venue housed in the c. 1840 brick carriage house beautifully situated behind the historic Cayuga Museum in Auburn, NY. Completely renovated in 2011, Theater Mack combines the charm of the 19th century carriage house it once was with exquisitely designed modern amenities.
Nestled on the banks of the Cowaselon Creek, in Madison County's picturesque countryside, Wolf Oak Acres has 180 acres of ponds, gorges, woods, fields, creeks, streams, waterfalls and gardens at your disposal. Celebrate your event in the most unique setting, where you will create memories to last a lifetime.
The Garden Room is an ideal place to hold weddings, rehearsal dinners, birthday or anniversary parties or any special occasion you may have.
At The Farmers' Museum, the Louis C. Jones Center provides an ideal setting for wedding receptions of all styles from informal barbecues to the most elegant dinner.
The Rosamond Gifford Zoo is always an exciting adventure for all your social events. We will make sure that you have everything you need to create an outstanding event.


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This video of a shootout between police officers and a gunman on Feb. 26, 2013, in the 800 block of North Branciforte Avenue in Santa Cruz was provided to NBC11.
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( Courtesy of Creedence Clearwater )
Creedence Clearwater Revisited brings CCR classics to town
Read our interview with Doug 'Cosmo' Clifford, who leads his current band into the Mountain Winery in Saratoga.
(Photo by Darren Carroll/Getty Images)
Did Tiger Woods cheat with Amanda Dufner?
Lindsey Vonn reportedly caught golfer with his competitor's ex-wife, which is likely why they aren't dating anymore.


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Seacam reinvents the Nikonos RS 13mm
At the recent ADEX show, Seacam owner Harald Hordosch was displaying a converted Nikonos RS 13mm lens on his stand. The company is re-housing the lens and using the original glass as a lens port.
Video: Darren Jew, underwater photographer and Canon master
Darren Jew is an underwater photographer and Canon master. This video highlights his return to Tonga to photograph humpback whales. The video was shot by Untitled Filmworks' Abraham Joffe.
Show coverage: ADEX 2014
ADEX is Asia's largest underwater and diving exhibition. Located in the Marina Bay Sands Expo center, Singapore, the show attracts attendees and exhibitors from all over Asia. As is frequently the case, underwater imaging is well represented at the show with stands from major brands as well as local retailers. Wetpixel is on site and posting "live" coverage.
Video: Anchovy fireworks underwater
In this clip from the MacGillivray Freeman IMAX film Journey to the South Pacific, the filmmakers capture an impressive underwater show by a school of anchovy.
Wetpixel @ ADEX 2014
The annual Asian Dive Exhibition (ADEX) kicks off on Friday 11 April at the iconic Marina Bay Sands, Singapore. ADEX has a reputation for being the Far East's major annual dive show and hence, Wetpixel will be there reporting on the products and events on display in our usual "live" way. Please keep checking back here for updates. In addition, Wetpixel and Scubacam are hosting the ADEX imaging party, which is being held at ME@OUE on the evening of the first day. If you are in Singapore, please come along, say hi and have a drink with us!
Video: Rare oarfish filmed in Baja, Mexico
On a Shedd Aquarium trip to Baja, Mexico last month two rare 15-foot oarfish (Regalecus glesne) were filmed swimming in the shallows. Oarfish are deepwater fish and rarely venture close to shore.
Sony announces α7S mirrorless camera
Earlier in the week, Sony announced the release of their α7S mirrorless camera. This features a 12.2 megapixel full frame sensor with a claimed ISO range of 50 – 4096002 with "low noise". In addition,it offers 4K video to an external recording device, with information being taken from the whole sensor width. Autofocus is the same as that of the α7R.
Gates trails new TVL55 monitor housing
Gates Underwater Products has released details of their forthcoming TVL55 housing for the TV Logic VFM-058W field monitor. The monitor gives numerous pro options including false color, vectorscope and waveform exposure monitoring as well as peaking and magnify focus tools. The housing form-fits the monitor and is constructed of aluminum and stainless steel.
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We spent three nights here while visiting Jasper National Park. We camped right by the creek so it was quiet. It is a very large campground and it was busy on the weekend. The road is near but if you camp by the creek you don't hear the road noise.
We arrived to our campsite after dark, but before the 11PM fire curfew. It was nice having a pile of firewood waiting for us at our site! The bathhouse was not far and was as clean as one would expect at a campsite. We didn't get to enjoy the views until the morning, but we camped right next to the...
My wife and I tented at the Wapiti Campground for three nights in August 2014. We used this campground as a jumping off point for day hiking in the Jasper area.
The campsites are slightly wooded, but more open than you might expect in the area. However, the Jasper area isn't nearly as busy as its neighbor to the south...
Real pleasure to spend some days here. The Wapitis really walk around in the evening, fires allowed, wood for free with a nice fire pit. Great place from where to visit Jasper and surroundings.
Bathrooms relatively clean, sani dump for free on the site.
Love, love, love this campground!! Was there second week in July 2014 but reserved my campsite online back in May. Campsite was quite large, private and sat on top of a cliff overlooking the Athabasca River. HEAVEN! Had only booked for 2 nights but decided to stay another 2. Couldn't get the same campsite again so stayed in 2 others,...
Although we had not booked we managed to get a powered walk in site in the car parking area. After touring Canada and staying on expensive crowded city sites this was not an issue to us at this point, just be prepared to be close to your neighbours.
The staff we found to be professional and friendly unlike the Lake...
Stayed here 4 nights this July. The site was nice, nothing fancy but had elk come through our site almost everyday! Biking/walking trails are nice.
- Look at the site online before booking. We drive around and glad we looked at our site. We have a 24' 5th wheel and there were sites that it would of been very...
We ended our camping at Wapiti campgrounds, which is right across the way from Whistlers. The bathrooms and shower facilities were clean and well-maintained (park-ran bathrooms are pretty much all the same). The firewood situation was lacking. Maybe it was the time of year to blame, but the wood pile looked like mulch with a sprinkling of a few slabs...
We got to pick our site right off the river. The bathrooms were clean and staff was great. There was a bear who had come by the campground and they drove past every 15-20 minutes to check for sitings and reassure people. My 2nd favorite campground in jasper
Thanks for your review! if this is your second favourite campground in Jaspeer, which one is your first?
We tent camped here on way home from Alaska. We did not have reservations, but had no trouble getting a site. Although on this trip we were just passing through, I think this campground would be an excellent base for exploring the park, plus it is close enough to town if you don't feel like cooking a meal or need...
How far in advance do you have to reserve a site? I'm looking at the site and it has absolutely nothing available.
Does wapiti have a parking lot where extra vehicles may be parked ?
Hi Team,
I was wondering if you can fish at the Wapiti campgrounds? Does anyone know? And what would be required?
Hey I hoping to reserve a site on the outer/ river side off RR or FF, what are the numbers I should be looking at? I can't seem to find a map with site numbers online! Thanks
wondering what sites are next to the river ? im going to y 2 is that close
See all questions


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On May 23, 2008, the FSA notified Dresdner Kleinwort that it had been placed on its 'firm watch-list' due to the fragility of its business. This assessment set in motion a chain of events that culminated with yesterday's High Court judgment in which Commerzbank was found liable to pay retention bonuses promised to front and back office employees totalling approximately €50m.
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Original recipe yields 8 servings
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Ready In
I followed this recipe exactly BUT I added 1 more cup of water and 1 more cup of chicken broth as I had more ham than it called for and I'm glad I did. WOW did this turn out good and so easy to...
This was delicious! I added more liquid and a can of diced tomatoes. It was even better on the second day. A great meal with some hearty bread or a grilled cheese sandwich.
This was delicious. I left out the ham bone...didn't have one and added a can of chopped tomatoes. The whole family loved it!!!


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Mt Fuji, Lake Ashi and Bullet Train Day Trip from Tokyo
We've selected the best candid trip photos submitted by our users to help you decide if the Mt Fuji, Lake Ashi and Bullet Train Day Trip from Tokyo is right for you. Make the most of your next trip to Tokyo with Viator's exclusive Photo Galleries.
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100 yr old cherry blossom tree Hanoke
April 2013
100 yr old cherry blossom tree Hanoke
Station 4
April 2013
Russell W
United Kingdom
Mt FUJI
monte fuji desde bus
April 2013
monte fuji desde bus
Sometimes the weather is against you!!
April 2013
The view from the cable car at Hakone
Mount Fuji
April 2013
Mount Fuji
At the end of the cable car in Hakone
March 2013
Kabby Villacorta
At the end of the cable car in Hakone
Fresh Air from Mount Fuji for sale!
February 2013
This bottle cost 1000 yen o.O
Mount Fuji
February 2013
Was super lucky to have a clear view of the great Mount Fuji !! Though it was winter and there was snow so we couldn't go up to the fifth station but stayed at fourth instead.
Sunsetting...A Touch of Red.
January 2013
A touch of red. Got down from cruising...a sight of 'a touch of red'...completed the journey beautifully.
Mt Fuji...
January 2013
Breath taking...
Snow at Mount Fuji
December 2012
Myself with snow at Fifth Stop at Mount Fuji. I was lucky since the sky was clear and managed to reach the Firth Stop, unless if yoy go during summer, you can walk to reach the peak.


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Suncast Multi-Purpose Storage ShedItem # HN-SUN155
- Durable resin construction with double walls
- Light taupe color with mocha accents
- Lockable lid for security
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- Dimensions: 7.33L x 3W x 2.83H feet
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For my application (garbage cans) it was perfect, though domed lids won't fit. I can fit 3 cans and there is enough room left for some bulky stuff. The instruction manual contains language that warns the plastic may get brittle in cold weather, so I'm waiting for one or two winters to pass before giving it a full 5 stars.
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Loaded Christmas Wreath with red ribbon, isolated on white
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Celebrating 10 years
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International Hotline: +44 1753 491470
Excellent, 9.6 out of 10
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Great service very quick to respond to emails very pleased with the product.
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It was a very smooth transaction from order to delivery. We are a return customer with additional requirements and delighted that costs were not applied for additional art work required from our new logo and strap line. Really happy about the delivery time as order arrived 4 days ahead of ETA. Would
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This is the third time we have used USB Flash Drive and have been very pleased each time. Friendly and helpful staff who are always willing to help. We have always been delighted with the products.Their prices are very competitive and they deliver quickly. We will definitely be using them again.
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A branded USB stick is a great way to say "Thank you" , "Welcome onboard" or even "Happy Christmas" - all whilst creating brand awareness for your company.
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text: Stocks Invensys shares jump on rail deal Add to ... Reuters Published Friday, Nov. 30, 2012 9:45AM EST Last updated Friday, Nov. 30, 2012 9:45AM EST Invensys shares jump by 37% in two days after Siemens said it was paying £1.74 bln for its railway signalling company. Joel Flynn reports. Watch More Video: Greek negotiator says bailout offer was easy to refuse Facebook unveils subtle changes to its logo Whole Foods CEOs apologize for overcharging Countdown on to Greek vote Vancouver housing heats up, but it's not too hot to handle Market Call Tonight: Top Picks from Middlefield Group's Andy Nasr Canadian bank stocks underperform in first half of year Is China a bubble about to burst? Potash Corp. wants face time with K+S Blaming 'foreign puppets' for China's stock markets rout Plan now to avoid a financially-uncertain retirement Another Sears Canada CEO out: A turnaround plan is long overdue BP settles U.S. oil spill claims for $18.7 billion K+S rejects $8.6B takeover proposal by Potash Corp. U.S. adds 223,000 jobs in June Creditors to Greece: No more talks until after referendum Strike begins at nine Loblaw-owned stores Athens is 'like winter,' say local business owners Bull vs. Bear: Should you give your kids an allowance? Market Call Tonight - Top Picks Comments AA More Related to this Story Fiscal Cliff Video: Hill meetings fail in progress on fiscal cliff Economy Video: Bank of Japan at a turning point?


text: In Chapter 6 of 18 interaction designer and researcher Lauren Serota discusses where she finds purpose in her career. Specifically, through her social sciences background and design research, Serota finds purpose learning to make things for people. As a practicing designer, she notes product design - interaction, fashion, graphic, etc. - is about value added utility. To identify this utility, she draws upon social science experience in anthropology, sociology in qualitative marketing research.


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Best of Boston
BEST Coffee Shop
Boston Common Coffee Co.
Rumor has it, the strong java at this American-style café has found fans even among the traditionalists at nearby coffee-roaster Polcari's. read more»
Espresso Royale
Offering the consistency of a chain minus the deadening corporate feel, it strikes the right note with BSO crowds and local music students. read more»
Mul's Diner
A cup at Mul's is always bracing, and made even better by the presence of myriad cops, reporters, and pols hanging out at the legendary greasy spoon. read more»
Zumes Coffee House
Opened last year, locally owned Zumes has won over Townies with its upscale tea and coffee drinks and do-lounge-around décor. read more»
Emack & Bolio's
The local ice cream chain's flagship serves up plain old joe, plus the requisite mocha-half-caf-foamed-and-dusted folderol we love. read more»
2nd Cup Café
Pedigreed beans (George Howell) ground and brewed in small batches make for the freshest refueling stop on the block. read more»
Uptown Espresso
It's not hard to miss Uptown Espresso, tucked into the first floor of a townhouse in the South End—although once you know it's there, it's virtually impossible to walk past. The coffee, a dark roast from upstate New York, is… read more»
J.P. Licks
No, people, you can't eat ice cream every day. But thanks to five blends of java, you can get a daily J.P. Licks fix. read more»
Cafe Pamplona
Waiters in white shirts and black pants serve strong cafe con leche to an eclectic cast of regulars. read more»
Martin's Coffee Shop
This cozy diner offers a hearty breakfast with your cup of joe. read more»


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New Music From PRINCE! "HARDROCKLOVER" Listen Now!!!
The one n funky PRINCE has released a new song entitled "HARDROCKLOVER" today. The announcement came via his twitter account (PRINCE3EG) and posted to Soundcloud.
The music icon sings and speaks in his lower voice speaking of his "HARDROCKLOVER" from a R.E.M. (Rapid Eye Movement) dream and then seeing if he can make this woman scream.
A shout to Red Bull and Patron "Ain't No Rapper Trying To Be A Singer" reaps of shades of "Dead On It" from The Black Album from Prince along a light stab at Sade and Babyface over a blistering guitar solo that is either Prince or Donna Grantis getting it in from his band 3RDEYEGIRL.
Who says nothing good ever happens after midnight???!!
Prince promised new music was coming this summer and on the 1st of July, Prince has delivered in full force.-DocFB
Diagnosis: A Hot HARDROCK Summer....indeed!
PRINCE & 3RDEYEGIRL Take Over The White House & D.C. With Stevie Wonder!
PRINCE & 3RDEYEGIRL performed a special concert at the White House on Saturday night along with a special appearance by Stevie Wonder before performing 2 sold out shows at the Warner Theater Sunday night where the late show featured Stevie Wonder as well.
The Sunday shows were announced earlier this week as part of Prince's #HITandRun Tour and the White House show was done on the hush hush. With the Secret Service in place as well as Prince's own no cell phone policy, if it wasn't for V.I.P's like Re.v Al Sharpton, Russell Wilson, Ciara, and Jon Bon Jovi, there may have been no details about his 2 hour show that featured Wonder on a version of "Signed, Sealed, Delivered, I'm Yours". No word if Tipper Gore was there but there was a Housequake for sure at 1600 Penn!
As for Sunday's shows, The Washington Post gave 4 observations that are interesting.
In another article said that Prince may be the greatest to ever do what he does.
Judith Hill also performed with Prince.
UNBREAKABLE! Janet Jackson Announces New World Tour!
Janet Jackson has announced her first tour in 4 years with the first date being on August 31st. It is being called "The UNBREAKABLE World Tour" and so far there are 36 tour dates.
Of the 36 tour dates, 30 are being promoted by Live Nation and it will take Miss Jackson through the U.S. and Canada.
Tickets will go on sale on JanetJackson.com June 22nd with an American Express pre-sale on June 15th.
Additional shows for the world-wide tour will be announced at a later date.
Release Date For DURAN DURAN Album & Tour Dates; 1st Single To Feature JANELLE MONÁE!
Duran Duran's new album will be titled "Paper Gods" and will be released in the U.S. on September 18th and the rest of the world on September 11th.
The first single is entitled "Pressure Off" and will feature JANELLE MONÁE.
Singer Simon Le Bon, keyboardist Nick Rhodes, bassist, John Taylor, and drummer Roger Taylor recorded the album in London with producers Nile Rodgers, Mark Ronson, Josh Blair,and Mr Hudson. The record features special guests Janelle Monáe (on the first single "Pressure Off"), former Red Hot Chili Peppers guitarist John Frusciante, Canadian Juno-Award winning singer Kiesza, British singer/songwriter Mr Hudson,violinist Davidé Rossi and actress Lindsay Lohan. The album was mixed by Mark 'Spike' Stent.Paper Gods will be available for pre-order and "Pressure Off" will be available for purchase this week.
For more on the new DURAN DURAN album & tour dates, click here!
The Next Stop On PRINCE's HIT And RUN Tour Is….Washington, D.C.!
PRINCE & 3RDEYEGIRL are bringing their HIT and RUN tour to Washington, D.C. this week.
Judith Hill will also be a part of the entertainment.
It was announced via Live Nation's D.C. Twitter this past hour.
The venue is D.C.'s Warner Theatre and will take place on 06/14. Tickets will go on sale this Thursday 06/11 at noon local time on LiveNation.com
Capacity for the Warner Theatre is a little over 1,800.-DocFB
Diagnosis: D.C. u ready 2 FUNKNROLL????
Come On & Get Some! Royal Blood Add Headlining Tour Dates!
BRIT and NME Award-winning UK duo Royal Blood have announced additional headlining U.S. dates to take place this fall.
The dates are in addition to the previously announced SOLD OUT headlining dates, performances at Governor's Ball, Sasquatch, Bonnaroo, Life Is Beautiful, ACL, and stadium dates with the Foo Fighters.
The live video for "Little Monsters" from Tokyo debuted on Howard Stern today.
The additional headlining tour dates are as follows:
September 24 - The Observatory - Santa Ana, CA
September 25 - House of Blues - San Diego, CA
September 28 - The Marquee - Tempe, AZ
October 6 - Cain's Ballroom - Tulsa, OK
Diagnosis: For full tour dates with Foo Fighters & more, click here!
Donation Recipients Of PRINCE's "Rally 4 Peace" Concert Announced; New Single Available On i-Tunes
Along with $35,000 dollars that Tidal donated for the first 60 minutes of PRINCE's "Rally 4 Peace" concert last month in Baltimore, Prince donated a portion of the concert proceeds and those recipients have been announced.
Those recipients are the NAACP's Afro-Academic, Cultural, Technological and Scientific Olympics (ACT-SO) and the city's YouthWorks and OneBaltimore programs. The amount of money donated has not been disclosed.
Prince has also released the "Baltimore" song featuring Eryn Allen Kane on iTunes. This is the newly updated orchestra version of the song.-DocFB
Diagnosis: "The system is broken. It's going to take the young people to fix it this time. We need new ideas, new life,. The next time I come to Baltimore I want to stay in a hotel owned by you."-Prince


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Based on GPS technology, this fleet tracking system equips public works managers with tools to help streamline fleet management, reduce costs and improve productivity in the field.
The Brief Relief disposable urinal bag provides a safe, convenient alternative when a bathroom is needed in the field, but none is available.
This Carhartt high-visibility, Class-3 sweatshirt combines visibility and warmth during cold-weather working conditions.
Profiles of the American Public Works Association's 2013 award recipients.
Thomas Montgomery has seen the population of Hastings, Minn., almost double.
Austin, Texas, public works director strives to work with the community and influence the workforce.
Putnam County, Fla., official believes public works touches the lives of every single person.
Public works director's team in Lexington, Mass., steps up during emergencies.
Her career enables Melissa Gentry to enhance the quality of life throughout Columbia, S.C.
Consultant is most proud of educating the future leaders of the public works industry.
Copyright ©
2015 Hanley Wood Media, Inc. All rights reserved.


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Tag Archives: South Kaibab Trail
10 Tips For Getting a Hard-to-Get National Park Backcountry Permit
By Michael Lanza
The first time I backpacked in Yosemite National Park, more than 20 years ago, I applied months in advance for a permit to start at the park's most popular trailhead, Happy Isles in Yosemite Valley—and I got it. I had no idea at the time how lucky I was. I've since been shot down trying to get permits for popular hikes in parks like Yosemite, Grand Canyon, and Glacier. But I've also learned a few tricks for landing coveted backcountry permits in those flagship parks—which all receive far more requests for permit reservations than they can accommodate. Continue reading →
Photo Gallery: Hiking Across the Grand Canyon
By Michael Lanza
Whether you backpack it or hike it in one very long day, trekking across the Grand Canyon from the South Rim to the North Rim is one of our National Park System's most scenic and aspirational adventures, in one of the planet's most magnificent and unfathomable landscapes. For the ultra-fit and experienced, hiking across and back in a day—known as a rim-to-rim-to-rim or "r2r2r," and comprising at least 44 miles and 11,000 vertical feet—could be the greatest single day of hiking of your life (unless, of course, you do it again). Continue reading →
Ask Me: Which Dayhike or Two-Day Backpacking Trip Should Our Family Take in the Grand Canyon?
What's your recommendation from the Grand Canyon's South Rim for a medium dayhike? We're going to the Grand Canyon over spring break in the last week of March, four of us. We will get there Saturday and have Sunday, Monday morning. Might look into Sunday night backpacking permit cancellations. We have a camping spot for dayhiking at this point.
Boise, ID Continue reading →
Ask Me: Tips For Hiking or Trail Running the Grand Canyon Rim to Rim
I'm happy to have run across your website. The pictures of the Grand Canyon rim to rim to rim (r2r2r) hike are spectacular and only enhance the anticipation and excitement for my own upcoming rim-to-rim (r2r) run. I have several questions for you about it. Continue reading →
My Top 10 Family Adventures
By Michael Lanza
How many outdoor trips do you have on the calendar for 2015 already? I have four, with others in active planning stages. For me, this is the time of year for pulling out maps and guidebooks and poring over my list of adventures I want to take. My document slugged "Trip Ideas" is now 15,234 words long, and growing. I need to get busy—and so do you. To help you out with ideas and inspiration for next year, here are my Top 10 Family Adventures at The Big Outside, ranging from climbing Mount St. Helens to backpacking in the Grand Canyon and cross-country skiing in Yellowstone. Continue reading →


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The Global FlyFisher - The Largest and Best Place to go for Online Fly Fishing and Fly Tying
Step 6 - JC
Add the Jungle Cock, a Pro Disc or Cone and cut the tube in both ends. Melt in the front and finally mount a Pro hook holder in the rear.
Part of the theme:


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Please refer to the Details at the foot of the page for size and measurement information.
A true display of elegance, this necklace and earring set features simulated pearls, pave designed beads, lobster claw closure and measures 34 inches with a 3 inch extender. Matching simulated pearl earrings are included.
Web Id: P000315309


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Sisters in Our Global Network Say:
"I am an African American Woman living in the Middle East. I want to join in the conversation of Sisterhood Agenda because I believe that I could offer some insight on younger women of color to 'think beyond the borders' of leading an adventurous life after they contribute to their communities. Thereafter, they can bring home what they've learned globally so they can enrich their communities even more."
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Originally written on Fox Sports | Last updated 1/15/13
If Butler is to continue its longest winning streak in nearly two years, it must do so without leading scorer Rotnei Clarke. Hoping to get by minus their injured senior guard, the No. 13 Bulldogs try for a 12th consecutive victory Wednesday night against Richmond in their first Atlantic 10 home game. Butler (14-2, 2-0) is off to its best start since opening 19-1 in 2008-09, but it will be without Clarke for at least this contest and Saturday's showdown against eighth-ranked Gonzaga. Among the A-10 leaders with 16.3 points per game and 44.4 percent 3-point shooting, Clarke sprained his neck after crashing into the basket support while being fouled as he drove for a layup in Saturday's 79-73 win at Dayton. Despite being taken off the court on a stretcher, Clarke was able to move his arms and legs and gave a thumbs up on the way out of the arena. "I feel blessed to be walking," said Clarke, who spent his first three seasons at Arkansas. "When I hit my head, I rolled over and I coul...
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Vito Schnabel, rumored boyfriend of Demi Moore, is seen going for a swim in South Beach, Miami on December 6, 2012.
Summer is upon us and that could only mean one thing: Swimsuit season is finally here.
Caitlyn Jenner is giving thanks for the freedom to be herself on this very special Independence Day.
America's founding fathers would have favorited Chelsea Handler's salute to our freedom in a video of her 'liberated' water ski ride.


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2002 Mercedes-Benz E320 Q&A
2002 Mercedes-Benz E320 Question: My key sometimes won't turn in the ignition.
This has been intermittent but getting more frequent and today I was stuck for a good 10 minutes before it decided to allow me to start. I have other lock problems which I am living with (343,000 miles on vehicle) but really don't want to scrap the car over this. I have tried opening and closing the door, flexing steering wheel, etc. It seems the key is just not engaging when put in. - Paul Cohn
Answer 1
replace the ignition barrel-QUICKLY.If it totally carks it, you gotta start with a chainsaw to get it out.Buy a cd-rom manual for your model. they're cheap, I bought mine off the net, even though I am licensed mechanic. If it's the same as the earlier ones,unscrew bezel surround off lock, turn they key to accessory position, i think it is, insert smallish probe or pin into hole in the thing and pull it out. Probably gotta buy one from dealer so take crutches so you can get home after he removes your left leg to pay for it. Not a big job if its the same as mine. This happens to a few of the models, so don't worry. It's an excellent system, but they do wear out. - eric57h
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