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fps tips
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Mess around with various control schemes and look sensitivity. Overall though you just need to practice. Beat the singleplayer on easy,normal,and maybe even try hard on some games.craigalan23
Exactly what this guy said. I never had this problem because i got started into shooter games at age 7 or 8.....so i am great at them by instinct.
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of all my frnds im the worst at fps games and most of them dont have a console at all any tips to help me be better at fps beside the obivous play more lolsrdjan311
I think im pretty good at FPS games in general, and a top tip from me would be to lower your horizontal sensitivity. I was part of a little league we ran for CoD4 and i was the only person who used low sensitivity for that, and i won by some margin. Other than that, practice makes perfect, you will find some FPS games will come naturally, some will require work. Call of Duty has always come naturally to me, whereas i picked up Resistance 2 and could only get about 1.5:1 on the kills/death ratio.
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of all my frnds im the worst at fps games and most of them dont have a console at all any tips to help me be better at fps beside the obivous play more lolsrdjan311
I also am not that good at FPS games, but here are some tips that help me survive:
1- Take cover at every opportunity. All it takes is one head shot to kill you, so don't give the enemy the opportunity.
2- Always reload when you're taking cover. You don't want to expose your position and be firing with a near empty clip.
3- Focus on the red reticule. Don't fore your weapon unless the reticule is red, otherwise kickback will throw off your balance slightly, and also you're wasting ammo.
4- Familiarize yourself with the enemies position. Fire your weapon at the enemy, not the enemies general direction.
5- Also, (this one may sound wierd) play on the hardest difficulty. The extreme challenge will force you to learn and absorb each and every thing that can get you killed. These skills will translate into your play style, and you will fing the challenge more and more bearable.
Hope this helps a bit.
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Category: baby name questions
Barbie writes:
I would like to honor my recently deceased father, Early Bernard, but I am drawing a blank! I just cannot see myself naming my child a name that would be shortened to Earl. His nickname was Early Bird, so I have flirted the idea of incorporating Bird somehow. But how?
Our four daughters are Taegan Elizabeth Claire, Madeleine Alexandria Rose, Julie Isabella Maria, and Willow Delilah Blue. As you can see, I like a variety of names.
I gave them all three names for personal reasons, and my son will have three names as well. I would prefer that no two of my children have the same first initial, so J, M, T, and W are out.
The Name Sage replies:
By Abby Sandel
Tanecia writes:
We are expecting our third child. We have a boy and a girl already: Cruz Andres and Veda Josephine. I like that both of their names are four letters (though we're not committed to four letters) and have spiritual ties, but I can't seem to find a name that I truly love for a third child.
Our top names so far are Makaio and Eden. We have some family names we might use for the middles. I would love if you could offer me any suggestions at all. I don't have any set rules for the names, but I want to love it, and I also want it to flow with Cruz and Veda.
Our last name is a long, common one – starts with an R, ends with a 'z' sound.
The Name Sage replies:
Alison writes:
We need the perfect name for our fourth daughter! Our daughters are Ellyanna Jane, Vivienne Renee, and Hannalise Olive.
We're looking for a long name – three or more syllables, with a similar style to her sisters' names. But it needs to have a different sound and dominant letters, so we can't repeat anna/enne/lise/viv/elly.
Our last name starts with a B, so no B names, please! Other family names to avoid: Jennifer, Cheryl, Kristy, Kirsten, Isabel, Amelia, Anna, Skye, Liberty, Pollyanna, Tiffany, and Felicity.
Our current shortlist consists of Olivia, Lydia, Everly, Lavinia, and Rosalie.
The Name Sage says:
Welcome to Nameberry's newest column, The Name Sage. Every week, I'll answer one reader's questions about naming a baby-on-the-way, or general baby name angst. And here's the best part: we'd love it if you would add your thoughtful suggestions and comments to help expectant parents decide. The world needs more nicely named children, berries! Want to see your question featured? Please email email@example.com.
Kathleen and her husband are expecting their first child, a boy. She writes:
Here's our dilemma: my husband is in love with the name Peter.
While I don't love it, it has started to grow on me. My main concern is the dirty joke associated with it. Do you think that's still an issue these days? Also, can you suggest any some middle names to go with Peter?
If you've spent any time on Nameberry, you've probably discovered our thousands of lists created by our users — nearly 12,000 public lists, and over 60,000 if you count the private ones!
We feature one of these user lists every day on the site, to help people discover the best lists created by Nameberry visitors and to help spotlight all our creative berries. These user lists cover every topic imaginable, ranging from lots devoted to Favorite Names or Baby Name Ideas to such arcane topics as Names for Steampunk Aristocracy or Sky Gods and Goddesses of Greek Mythology.
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A man froze to death in McGolrick Park last week as advocates learned funding had been cut for a shelter.
The Strand was criticized for treating the homeless like "pests," not people.
The Strand Book Store recently removed signs warning outdoor sprinklers would go off at night.
The assault on a 62-year-old Brooklyn resident is being investigated as a hate crime, sources said.
Neighborhood in the Nineties is suing the city over a controversial West 95th Street shelter.
A new CityBench at 10th Avenue and 46th Street has become a magnet for the homeless, locals say.
The homeless man attacked four women in less than two and a half hours Monday night, police say.
Twenty-two men's and women's teams competed for a slot in the Homeless World Cup in Poland.
A man accused a homeless woman of denting his car and then slugged her in the face with an umbrella.
Andrey Ignatyev, 51, will face up to 25 years in prison at sentencing in Manhattan Criminal Court.
Male stars of some of Broadway's hottest shows will perform for charity at NYU.
Kayla Mitchell, who was believed to be homeless, was found under a tree near 14th Street.
Artist Fanny Allié is creating a sculpture of Christopher Gamble, who lived on the streets for 28 years.
Julian Salley, 27, was shot inside a building on West 33rd Street in Coney Island.
Walter Corcoran, 63, was found dead inside 88-14 Liberty Ave. Tuesday evening, cops said.
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Best Natural Disaster Movies
List Criteria: Vote for the greatest natural disaster films (in your opinion), regardless of how popular or successful they were at the box office.
Since mother nature is always to be respected, we've created a list the best natural disaster movies of all time for you to rank. Whether the focus is on earthquakes, hurricanes, volcanoes, or all of the above, these are considered to be the top natural disaster films by fans of the genre. The two biggest recent weather disaster films are 2012 and The Day After Tomorrow, but there are many other great movies about natural disasters that are worth watching too. Who can forget about Helen Hunt's performance in the 1996 film Twister? There was also Bruce Willis in 1998's Armageddon, which was poorly reviewed but is still considered a fan favorite.
Vote for your favorites below, but only if you've seen the movie. You can use this natural disaster movies list to find some great new films that you haven't already seen, and full trailers are available on this page for you to check out as well.
Clint Eastwood and Johnny Depp have both directed Natural disaster movies, as have many other great directors.
- 1 ReRank
- Region
- See list ranked by
- 1+ 107- 23
The Day After Tomorrow Emmy Rossum, Jake Gyllenhaal, Dennis Quaid
- 2+ 44- 5
Twister Helen Hunt, Philip Seymour Hoffman, Alexa Vega
- 3+ 89- 29
2012 Amanda Peet, Woody Harrelson, John Cusack
- 4+ 52- 13
added by JeniferN.Daly
Deep Impact Morgan Freeman, Robert Duvall, Elijah Wood
- 5+ 34- 9
Volcano Tommy Lee Jones, Don Cheadle, Anne Heche
- 6+ 32- 9
Armageddon Ben Affleck, Bruce Willis, Liv Tyler
- 7+ 15- 5
added by MarkDrinkle
The Core Hilary Swank, Stanley Tucci, Aaron Eckhart
- 8+ 27- 18
Earthquake Charlton Heston, Ava Gardner, Victoria Principal
- 9+ 29- 27
10.5 Kaley Cuoco, Beau Bridges, Kim Delaney
- 10+ 2- 0
new! & added by 4MINGTHOUGHTS
Night of the Twisters Devon Sawa, John Schneider, Laura Bertram
- 11+ 18- 23
10.5: Apocalypse Garcelle Beauvais, Frank Langella, Dean Cain
- 12+ 5- 16
San Francisco Clark Gable, Spencer Tracy, Jeanette MacDonald
- 13+ 6- 18
The Hurricane Dorothy Lamour, John Carradine, Mary Astor
- 14+ 7- 20
The Rains Came Myrna Loy, Tyrone Power, Joseph Schildkraut
- 15+ 7- 20
Krakatoa, East of Java Sal Mineo, Brian Keith, Maximilian Schell
- 16+ 5- 17
The Rains of Ranchipur Richard Burton, Lana Turner, Fred MacMurray
- 17+ 5- 18
Deluge Sidney Blackmer, Lois Wilson, Peggy Shannon
- 18+ 4- 16
Lady from Louisiana John Wayne, Dorothy Dandridge, Ona Munson
- 19+ 2- 16
Nihon Chinbotsu Kou Shibasaki, Hideaki Anno, Akira Emoto
- 20+ 2- 16
Birdemic: Shock and Terror Tippi Hedren, Alan Bagh, James Nguyen
- 21+ 2- 17
Japan Sinks Lorne Greene, Tetsurō Tamba, Nobuo Nakamura
- 22+ 2- 17
Everyone But Japan Sinks Yasutaka Tsutsui, Dave Spector, Minoru Kawasaki


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"The visibility dipped on the runway between 2am and 5am, but as it was way above the required minimum of 125 metres and 150 metres for small and large aircraft, there was no disruption," airport sources said.
"Arriving flights had to use the various categories of instrument landing system to land," they said.
"Flight operations were badly hit due to dense fog early this week leading to delay, cancellations and diversions of over 300 flights.But for last two days, operations are normal despite moderate to shallow fog at the airport," they said.


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VIEWS: 171 PAGES: 27 CATEGORY: Personal Finance POSTED ON: 3/12/2010 Public Domain
Recruitment and Selection HRM 2254 Marjo-Riitta Parzefall Hanken, 24.1.2007 The Objectives of the Lecture • To view the recent trends in the labour markets and their influence on HRM. • To discuss the recruitment process and alternative ways of recruiting employees. • To examine the selection process as a two-way- process. • To evaluate a range of selection methods and criteria. • To review approaches to selection decision-making. The Changing Context • Knowledge intensification of work • Demographic developments and diversity at the workplace • ICT, e-commerce • Increased customer importance and power • Increased and changed competition as a result of globalisation and internationalisation of goods, services, finance, information, workers... • Constant change: 'Here today, gone tomorrow' WORKERS AND WHOM YOU EMPLOY MAKE A DIFFERENCE !!! The War for Talent • The increased importance of 'intangible assests': in S&P 500 companies, up from 20% of the value of the company in 1980 to 70% in 2006. • Employer Branding = A targeted long term strategy to manage the awareness and perceptions of employees, potential employees and related stake-holders with regards to a particular firm (Backhaus & Tikoo, 2004). • A Image management? A form of new Paternalism? The Most Popular Employers among Business Students in Finland in 2006: 1. Nokia 8. Kone 2. Finnair 9. Fazer 3. L'Oreal 10. Amer sports 4. Ernst & Young 11. OP-ryhmä 5. Nordea 12. Sanoma WSOY 6. PwC 13. Suomen Pankki 7. Stockmann 14. UPM-Kymmene Contingency Perspective to HRM • The ownership, sector, size, tradition and the stage of development of the organization; • The degree of turbulence in the environment, PESTIL contexts external to the organization; • The approach of the senior executives and staff to HRM; • The approach to employment relationship; and • The competence, skills, capacity, reputation and track-record of HR staff. Implications for recruitment and selection? Recruitment and Selection Recruitment Selection • A process which involves • The process of attracting the application of qualified candidates from appropriate methods with whom it is possible to the aim of selecting and select and appoint appointing competent persons. competent workers. • A two-way process of • Similarities to marketing, communication and communicates about the establishing a positive firm. psychological contract. Recruitment & Selection as a System PESTIL Candidates Recruitment Selection Labour market Rejection Effective characteristics Exit employees Validation, review and organisational constraints Job Analysis & Person-Job Fit Job Analysis: • Determine the tasks and the attributes required from the employee to perform the tasks successfully. Person-Job Fit: 1) There are intrinsic individual differences. 2) There are different types of jobs. 3) Satisfaction is highest and turnover lowest when personality and occupation are in an agreement. Recently, more emphasis on finding employees who match organizational cultures/organizations rather than particular jobs. Person-Job Fit ??? Recruitment: Internal or External? Internal recruitment has certain advantages: Cultural control Motivating & rewarding effect as people know they have career possibilities Development of people through transfers Lower recruitment & selection costs, a faster process The person is known The person is likely to have realistic expectations ...And certain disadvantages: - Is new blood needed? A limited pool of candidates... - Are suitable persons available, and will they be 'released'… - How to make the job and the person connect… - What follows if the internal candidate who applies is not selected… About Recruitment • How do companies recruit? Figures from the UK 2003: 1. Advertisement in local press 2. Specialist journals 3. Corporate web-sites 4. Recruitment agencies 5. National news paper 6. Internal intranet 7. Word of mouth 8. Job service 9. Education liaison • ...... About Selection • Usually more than one method is used depending on: – The type of job; – The competence of the staff involved in the selection; – Administrative aspects; – Costs; and – Time factors. • Methods include: selection forms, CVs, tests (aptitude, intelligence, trainability, personality), group tests, interviews and assessment centres, work samples. Issues in Selection: • Validity: – Does the method assess all relevant aspects of the job? – Does the method predict current and/or future performance? – Validity is absolutely critical! • Reliability: – Consistency of the method. – Is it free from random error? • Use and interpretation of selection methods!!! – Is the decision criteria clear and systematically applied? Selection: Validity of Methods Examples of Assessment centre for 0.7 development correlations* between Structured interviews selection Ability tests 0.6 methods and Work sampling 0.5 employee Assessment centre for job performance: performance, Bio-data Personality assessment 0.4 *Ranges from 0 (no correlation) Unstructured interviews 0.3 to 1 (certain prediction) References, Interests, Years 0.1 of work experience (Bilbeam and Graphology, Astrology, Age 0 Corbridge, 2006) Selection: Interviews • A social encounter: more than a selection device. • Preferably structured than un-structured, experience- based than future-orientated. • Improve validity and reliability by being aware of: – The halo and horn effects; – The bias towards preferring similar personality characteristics to your own; and – Positive and negative expectancy through access to candidate information (e.g. CV). Selection: Interview Tips by Jack Welch, GE • Always look for integrity, intelligence and maturity. • 4-E and 1-P framework: – Energy: ability to 'go go go', enthusiasm and optimism. – Energize others: ability to inspire other team members, good knowledge of business and strong persuasion skills – Edge: the knowledge to know when to stop assessing and courage to make tough yes-or-no -decisions. – Execute: the ability to get the job done. – Passion: authentic excitement about work, love to learn and grow, juice for life in the veins! Selection: Assessment Centres • Multiple raters evaluate applicants'/employees' performance on a number of exercises, e.g. – solving a particular task in a team, interviews, individual tests • Used by 65% of large firms in UK • High level of predictive validity • Often somewhat limited construct validity • Viewed as fair and thorough by candidates • Recommendations: – Ensure that assessors are trained – Use situational exercises, i.e. closely related with real job situations – Use systematic observation by both experts on assessments (often consultants/psychologists) and the focal jobs Selection: Cognitive Ability Tests • Include those measuring general intelligence / ability and those measuring specific abilities / aptitudes • Three dominant facets: – Verbal comprehension: ability to understand and use written and spoken language. – Numerical ability: speed and accuracy with which one can solve artithmetic problems of all kinds. – Reasoning ability: inventing solutions to diverse problems. • Moderate to high validity in particular for complex jobs. Selection: The Big Five Personality Test + Plus - Minus High extraversion Happier, fun, better Impulsive, risky performance behaviours High agreeableness Slightly happier, do Too trusting, generally better perceived passive, compliant High Reliable, take less risks, Less creative and conscientiousness performance- orientated innovative High Happier, more satisfied, Nervousness emotional stability less stressed sometimes beneficial High openness to Creative, adaptable, In some occupations, experience easy-going convervatism beneficial? Selection: Biographical Data • Captures past behavior and performance as a predictor of future behavior; • "More of the same" is a rather stable predictor;…. • But be aware of: – References: Are past/current superiors, etc. really providing 'objective' information about the applicant? Lack of variance? – Data provided by the applicants: Is the person lying/distorting facts? – Written documents: How do you know that they are real? Remember to Submit Your Application! Selection as a Social Process Recruitment and selection procedures constitute the initial episodes in the developing relationship between individual and organization. (…) Social psychology then becomes a means of understanding the nature and development of this relationship, rather than the analysis of intrusive interpersonal behavior." (Herriot 1989: 171) Selection as a Social Process • Sharing realistic information; • Creating commitment and involvement through mutual exploration and joint decision-making; • Focus also on cultural match; and • Increases the likelihood of self-selection… Creation of a positive and mutual psychological contract between the employee and the employer! Selection Decision is Not the End... "If you want to keep staff then you have to look after them. That is why we try to create a campus like atmosphere at our office. We have top quality gourmet food available and in the evenings we run cookery classes. You also get Waitrose Direct, a grocery shopping service – who wants to waste their spare time by pushing a supermarket trolley? Every morning workers are offered free fruit with breakfast." HRM manager, a British IT firm Conclusions: • Recruitment and selection involve increasingly employer branding; • Recruitment and selection are two-way processes; • Recruitment and selection are both scientific and social processes; • Select carefully the best method for selection and selection decision-making! ' THANK YOU! Photo: Andreas Diehl
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Respond to Review of CLOSED: Truly A Vegan
by MichelleOJ
Review: Yeah, this is kind of a whole in the wall place but don't let that fool you! My husband & I eat here a few times a month despite the 20-30+ minutes getting there in LA traffic. The food is wonderful, I've never ordered something I didn't like. I'm floored by the option of having breakfast anytime of the day...when was the last time I was able to do that at a restaurant?? The pancakes are awesome- I wish they would let me in on their sercret. ;) I usually order breakfast or a sandwich or a noodle/rice dish. Hubby likes the lentil loaf as it's very filling and comes w/a hearty helping of fresh veggies & seasoned potatos. Definately try the soymilk shakes- YUM!! The staff is always very kind and friendly. We notice a lot of people come here for take-out. If we lived closed I'd be going broke ordering take-out from them several times a week. The prices are reasonable and the ingredients are fresh and healthy.
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marques colston - Page 2
Saints Injury Report: Marques Colston Misses Practice
Brees And Saints Still Far Apart On Contract
NFL's 10 Biggest Offseason Questions
Top 100 NFL Free Agents
New Orleans Saints fans know that Drew Brees, Marques Colston, and Carl Nicks are set to become free agents. Point being, the Saints have will have some work to do. Stars like Mario Williams, Matt Forte (pictured above), Ray Rice, and Wes Welker are other big free agent names for the 2012 offseason. Who are the top 100 NFL free agents?
Where Will The NFL's Top Free Agents End Up?
Taking A Look At The 15 Saints Eligible To Become Unrestricted Free Agents
Marques Colston's Future With Saints Uncertain Due To Free Agency
Grading The Saints' Week 11 Win Over the Falcons
Saints Sink Falcons In Overtime
The New Orleans Saints will go into the bye week at 7-3, sitting atop the NFC South after their overtime victory on the road against their arch rivals, the Atlanta Falcons. Saints kicker John Kasay nailed a 26 yard FG in sudden death. A short field was set-up for the offense after Atlanta elected to go for in on 4th and inches and werer stuffed by the New Orleans defense.


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Charles Jessold, Considered as a Murderer
By Wesley Stace
(Picador USA, Paperback, 9780312680107, 389pp.)
Publication Date: February 1, 2011
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One of The Wall Street Journal's Best fiction books of 2011
England, 1923. A gentleman critic named Leslie Shepherd tells the macabre story of a gifted young composer, Charles Jessold. On the eve of his revolutionary new opera's premiere, Jessold murders his wife and her lover, and then commits suicide in a scenario that strangely echoes the plot of his opera---which Shepherd has helped to write. The opera will never be performed.
Shepherd first shares his police testimony, then recalls his relationship with Jessold in his role as critic, biographer, and friend. And with each retelling of the story, significant new details cast light on the identity of the real victim in Jessold's tragedy.
This ambitiously intricate novel is set against a turbulent moment in music history, when atonal sounds first reverberated through the concert halls of Europe, just as the continent readied itself for war. What if Jessold's opera was not only a betrayal of Shepherd, but of England as well?
Wesley Stace has crafted a dazzling story of counter-melodies and counter-narratives that will keep you guessing to the end.
- The book's title—Charles Jessold, Considered as a Murderer—is slightly unusual and very specific. What are the literal and figurative ways in which the title may be understood?
Charles Jessold, Considered as a Murderer


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There are all kinds of things that we believe set SMM apart from the crowd — our culture, our process, our passion for creating remarkable and measurable campaigns. But those are just nice words unless you can back them up with the work you've done. We think you'll agree that we can.
SMM approaches talent recruitment from a marketing perspective and builds strong employer brands. LEARN MORE
Last week, as I stood on a New York City subway while it was barreling downtown, it occurred to me how each and every person within sight was staring at, listening to or tapping on their mobile device. To those of us centered in marketing, it is no secret that mobile is a major disruption of our traditional web strategies. Because billions of people are now connecting to the Internet and consuming media in different...READ MORE
Trying to hire? In 2015, the chances are that your candidates will type a job title into a search engine. This is why it is important to keep your job postings highly visible and optimized. If candidates can't find your postings, you won't get responses—but when your jobs are optimized, it can become one of the best ...READ MORE
SMM has been hired by the Town of Islip (TOI) to provide branding, advertising and digital services. The campaign will be designed to promote economic development in Islip and as an exceptional town in which to establish a business. The Town's Foreign Trade Zone ...READ MORE


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Spend a weekend discovering beautiful Limestone CityBook your trip!
Test your knowledge, challenge your friends
and earn contest entries!
Located in the heart of downtown at 275 Princess Street, Stone City Ales, while not the only local brewery, is the only one that operates as a bottle shop, brewery and tap room. The bottle shop opened on July 25, 2014 and all day had a steady stream of people anxious to get in to purchase their first growler. I was one of them.
The city of Kingston is a cheese lover's paradise, with many fine cheesemakers located just a hop, skip and a jump away. Take a short walk downtown or drive down the 401 to discover some of Canada's best artisan cheeses in an array of shapes, sizes, smells and colours from coast to coast to coast. As cheese lovers, we celebrate the passion and dedication of cheesemakers throughout the country – let's cheese out!
One will not find Kingston lacking for choices in Thai food, but if you are inclined to wander off busy Princess Street onto Sydenham Street downtown, you may perhaps find a spot you have not tried. Peering into its inviting windows, you will encounter a restaurant perfect for a quick weekday lunch or a quiet spot to have a date or catch up with friends.
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Orpheum Theatre calls Celebrity & Chef Cookoff a success
The annual event set a record for attendance this year.
The annual event set a record for attendance this year.
NBC is ending its business relationship with Donald Trump after his comments about Latinos.
A Detroit woman pleaded guilty Monday to killing two of her children and storing their bodies in a home freezer, saying she had no remorse.
Following a breakdown in talks, Greece is in the midst of the one of the most acute financial crises seen anywhere in the world in years.
Experts say this kind of social media pressure, she says, can lead to eating disorders.
A federal judge is giving a man accused of plotting to bomb an Army installation more time to review the evidence against him.
After a 13-year-old was bitten by an alligator, his father jumped in to rescue him.
You've always wished for more time in the day. Now, you've got it. Tuesday, June 30, 2015 will be 24 hours and 1 second long.
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Le Vele Dog 4 Piece Duvet Cover Set
This product has additional required/recommended options. To configure, add to your cart.
Special Offer:
12 Issues of Money Magazine
Included with purchase ($20 value).
Le Vele Dog 4 Piece Duvet Cover Set
Weights & Dimensions
|Product Type: Duvet set
|Size: Twin
|Number of Items Included: 4
|Pieces Included: 1 flat bed sheet, 1 duvet cover, 1 pillow case and 1 pillow sham
|Color: Multi-colored
|Material: Cotton
|Fade Resistant: Yes
|Lint Free: Yes
|Non-Pilling: Yes
|Moisture Wicking: Yes
|Organic: Yes
|Non-Toxic: Yes
|Thread Count: 305
|Duvet Cover Included: Yes
|Shams Included: Yes
|Pillow Cases Included: Yes
|Sheets Included: Yes
|Gender: Unisex
|Life Stage: Adult
|Reversible: Yes
|Textured: No
|Ruffled: No
|Button Tufted: No
|Hand Tacked: No
|Pre-Shrunk: Yes
|Ventilated: Yes
|Cleaning Method: Machine washable
|Drying Method: Tumble dry
|Iron Safe: Yes
|Product Care: Do not use strong liquid cleaners
|Country of Manufacture: Turkey
|Additional Parts Required: No
About the Manufacturer"Le Vele" presents an exquisite European line of Bedding Sets and blankets to indulge in beautiful bedding for the lavish bedroom. Le Vele's fine linen is made of 100% cotton with satin weaving for unsurpassed quality and softness. French designs are printed with the latest reactive dyeing technology showing vibrant colors and guarantee years of reusable life.
Le Vele Dog 4 Piece Duvet Cover Set
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Tell us what you think about this product. It will help us provide you with better products in the future and help your fellow shoppers make better purchases.Write the first review
OUR SKU # LEV1151Dog 4 Piece Duvet Cover Set is also sometimes listed under the following manufacturer numbers: LE454T


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Braeger Ford helped make these videos
We are still working to obtain content for your car, however the video above is believed to have similar characteristics as your car.
The video above shows how to replace blown fuses in the interior fuse box of your 2001 Honda Civic in addition to the fuse panel diagram location. Electrical components such as your map light, radio, heated seats, high beams, power windows all have fuses and if they suddenly stop working, chances are you have a fuse that has blown out. If your Civic is experiencing electrical problems, you should always check the fuses first, because they are relatively easy to check and cheap to change. Some Hondas have multiple interior fuse boxes including in the trunk - the video above will show you where the interior fuse box of your 2001 Civic is located. If your Civic has many options like a sunroof, navigation, heated seats, etc, the more fuses it has. Some components may have multiple fuses, so make sure you check all of the fuses that are linked to the component in question.
If you need to replace a blown fuse in your Civic, make sure you replace it with one that has the same amperage as the blown fuse. If checking and replacing the fuse for the component in question doesn't work, we recommend seeking assistance from a trusted professional mechanic. They should be able to figure out if the component needs to be replaced or if there is a short or some other problem with your Civic.
Flushing the coolant in your car is not that hard and will extend the life of your engine tremendously - learn how here!2001 Honda Civic EX 1.7L 4 Cyl. Coupe (2 Door)
See how to seal up minor power steering fluid leaks2001 Honda Civic EX 1.7L 4 Cyl. Coupe (2 Door)
There's no reason to check the washer fluid level without adding some - see how to do it here!2001 Honda Civic EX 1.7L 4 Cyl. Coupe (2 Door)
A few key tips will make jacking up your car much safer2001 Honda Civic EX 1.7L 4 Cyl. Coupe (2 Door)
Learn where your air filter is located and how to determine if it needs to be changed.2001 Honda Civic EX 1.7L 4 Cyl. Coupe (2 Door)
Harsh downshifts? Slipping gears? You might be low on transmission fluid2001 Honda Civic EX 1.7L 4 Cyl. Coupe (2 Door)


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Items tagged footwear industry in MV Collections
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Items per page: 10 50 (showing 51 - 60) 62 items
Shoe - Parker Coronal, 'Venito', Platform, Right, 1970s
One platform right shoe, Parker Coronal label, 'Venito' style. Made around the 1970s by Parker - 'styled' in New York. Possibly acquired by Paragon Shoes as a sample. Paragon Shoes Pt ...From: New York, United States Images: 1
Shoe - Sacha, 'Walk Tall', Platform Clog, Right, 1973
Alternative Name(s): Clog One right shoe, Sacha 'Walk Tall' label. This style was also available in black/cream, blue/white, red/white and apple green/white. Made in February 1973. Acq ...Images: 1
Shoe - Paragon, 'Pierre Fontaine', Tan & Brown Leather, Left, circa 1970s
One tan and brown leather Paragon shoe, Pierre Fontaine label, with a green leather leaf motif on the front. Date unknown (possibly 1970s). Paragon Shoes Pty Ltd was one of the most si ...From: Melbourne, Australia Images: 1
Shoe - Sacha, Right, 1970s
Alternative Name(s): Clog, Mule Dark green platform right shoe, made in the 1970s, labelled 'Sacha'. Acquired by Paragon as a sample from Wilf Sparks, who acted as their representative ...Images: 1
Shoe - Paragon, Parisienne, 'Bandit',1980s
One Paragon right shoe, Parisienne label, from the 'Bandit', 'Parrot Collection'. Made in the 1980s. It was one of the first relatively flat-heeled shoes that Paragon made. Previously, ...From: Melbourne, Australia Images: 2
Shoe - Paragon, 'Romantica', Quad, Left, 1960s
Single stiletto leather shoe, 1960s, 'Romantica', made by Paragon Shoes, 'fashioned' in Italy. This was a sample, and was not worn by the donor. Paragon Shoes Pty Ltd was one of the mo ...From: Melbourne, Australia Images: 1
Box Label - Smiley Productions, 'Spotswood', Balls Moccasins, 1992
Rectangular pink paper box label with black printing on one side, and glue residual on the reverse. It was used during production of the Australian feature film `Spotswood', released i ...Images: 1
Address Plate - Australian Boot Trade Employees' Federation, circa 1980-1985
Metal Address Plate for the Australian Boot Trade Employees' Federation, circa 1980-1985. It is one of a set of 34 Address Plates used on a label printing machine which was employed for ...Images: 1
Poster - 60,000 Aussie Jobs Could be out of Fashion, Textile, Clothing & Footwear Unions, ...
Poster authorised by the Australian Textile, Clothing and Footwear Unions and the Textile Clothing and Footwear Council of Australia (TCFCA), circa 1988, promoting the industry's unions ...Images: 1
Ribbon - Australian Boot Trade Employees Federation, 1908-1939
Ribbon belonging to the Victorian branch of the Australian Boot Trade Employees' Federation. This item is part of a collection relating to Australian trade unions and the Eight Hour Da ...Images: 1


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Why did you choose this product?
Use this rug in my main living area. It is not an expensive rug and it's thin but it's gorgeous and the center piece of the room. I know it won't last forever but I've had it in my home for over a year and it has held up beautifully....
This durable and hardwearing, 8'2' x 10' area rug will survive in even the most demanding of households. The brown rug features a contemporary, abstract design in green, beige, red, and ivory and is manufactured from stain-resistant polypropylene.
ITEM#: 13318853A unique abstract print accentuates the durable construction of this rug. This rug is stain-resistant and features shades of brown, green, beige, red and ivory.
- Primary materials: Polypropylene
- Pile height: 0.393 inches
- Style: Contemporary
- Primary color: Brown
- Secondary colors: Green, beige, red, ivory
- Pattern: Abstract
Tip: We recommend the use of a non-skid pad to keep the rug in place on smooth surfaces.
All rug sizes are approximate. Due to the difference of monitor colors, some rug colors may vary slightly. We try to represent all rug colors accurately. Please refer to the text above for a description of the colors shown in the photo.
|Polypropylene Synthetic Fiber
|Abstract Print
|Weave Type
|Product Features
|Antimicrobial Stain Resistant
|Rug Type
|8'2 x 10'
|Model Number
Customer Reviews
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Use this rug in my main living area. It is not an expensive rug and it's thin but it's gorgeous and the center piece of the room. I know it won't last forever but I've had it in my home for over a year and it has held up beautifully.Read More
Nice for the price
I love this rug. I bought extra carpet pad when my carpets were replaced to use under this rug as it is a bit thin. With the pad it feels and looks great.Read More
Dull looking
Don't get me wrong this rug is of good quality but it looks dull. The colors don't pop and looks like its an old rugRead More
Great area rug for price
This is nice rug for the money! was surprise! great customer service and delivery.Read More
Quality, but just a little off-kilter
I've owned this rug for about 2 years. It's still beautiful. We vacuum it daily, since we have cats, and it holds up well. The colors are vibrant and beautiful, but do not detract from our furniture. We also bought the runner for our hallway. They look great together. The one complaint I have (and this may just be the artist in me whining) is that the circles do not always meet, or complete. It bugs me, but not enough to say that I wouldn't recommend the rug. Delivery: Prompt and professional Some people ask about whether or not the rugs lie flat. This one didn't initially, but it relaxed over a period of about a week. The runner in the hallway has never curled. Both rugs are substantial, quality rugs. They're the same quality that we'd have purchased in a local furniture shop for more than triple the price.Read More
Great rug!
This rug is great and looks amazing in our living room, but we have to vacuum it daily. The rug looks identical to the picture listed. It's so soft and plush and looks way more expensive than the price listed. Only down fall...this rug is a magnet for lint and our cat's hair, but I love it so much that we don't mind pulling the vacuum out. Plus, honestly, this was the only rug that both myself and my fiancee could agree on and we are both extremely picky people. I have our sofa on top of this so a rug pad was not needed. If you do the same, it will save you $40 for the pad.Read More
Great Rug...Great Price!
I purchased this large rug along with a matching small one for my living/dining and foyer area. The rugs are beautiful and I am very happy with them. The colors are pretty much as represented on-line... a brick red, brown, gold, beige, and a slate/cement gray that takes on different hues (blue or green) depending on the lighting. The rug is well constructed and very soft! The pattern varies slightly than pictured and even between the two rugs but that is what I expected and wanted......it does not look just stamped out but like it was cut from a larger piece of artwork. My rugs arrived in just a few short days and were packaged well. What a great price offered by Overstock....for a relatively small amount of money I was able to give my open living/dining foyer a completely new and updated look. I am very happy with this purchase.Read More
Very Soft, Good Quality
I was a little skeptic buying an area rug withough being able to see the colors in person. There are grey, olive green, khaki green, cream, deep/maroon red and dark brown. It is very beautiful and very soft. I have it over carpet and under an ottoman and it still lays flat against the floor. Adds a lot of dimension to the room. Great buy! Looks much more expensive than it was!Read More
A little bit disappointed
I love the pattern but was disappointed in the condition of the rug when it arrived. It was folded, not rolled, which caused very noticeable creases. Hopefully over time the rug will lay flat and the creases will not show.Read More
Great looking rug but had many creases
When I got the rug I was prepared to see some creases in it based on reviews written by others. When I unrolled it there were a lot and it looked pretty bad. At the advice of my husband, I laid it out in the sun on our driveway for a couple of hours. He said the hot pavement will act as an iron. It worked!! My rug looks fantastic. I laid it out again the next day for a couple more hours and I can't see 1 crease. I love this rug and am so happy I didn't have to return it thanks to my hubby!Read More
Questions & Answers
we need a new rug and I loved the colors and design
Is this a shag rug or a regular area rug?
Hello danielle0713, This is not a shag rug. Thank you for shopping with us!
rEGULAR NO SHAG.
Why does this rug come up under the area of "made in the USA"? I purchased it and it is actually made in Egypt :( I wish that I would have purchased a different rug, but I trusted the advertising on your website.
It may be a glitch, this is not made in the USA. Our made in USA products will have a logo on their product page.
I love the pattern of the rug, however it is very thin and lays flat even with daily vacuuming. I would love to get this pattern rug but with better quality, is it possible? Thank you
Unfortunately, this is the only rug with this pattern that we have in our inventory.
Shopping Tips & Inspiration
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Dipped in Gold
The glitter and glamour of gold is catching the eye as a 2015 home decor trend.
How to Size Your Room for an Area Rug
How to Size Your Room for an Area Rug from Overstock.com. Select the right size rug for any room using these tips. Shop with confidence for the perfect area rug size with help from this guide.
How to Choose an Area Rug for Your Bedroom
How to Choose an Area Rug for your Bedroom from Overstock.com. Here's how to narrow down your choices and find the area rug that's perfect for your room.
Take the Floor
Say goodbye to boring flooring! Transform your home from the ground up with attractive area rugs and eye-catching ottomans. Your space will never be the same once you add these brightening updates.
How to Care for Wool Rugs
How to Care for Wool Rugs from Overstock.com. With a gentle approach and a little time, you can keep your wool rugs looking beautiful for many years.
How to Protect Wood Floors with Area Rugs
How to Protect Wood Floors with Area Rugs from Overstock.com. The easiest way to protect wood floors from scratches and wear is to decorate with an area rug. This guide covers what you need to know.
Best Area Rugs for Christmas
Best Area Rugs for Christmas 2014 from Overstock.com. To help get you started on your search for the perfect rug, here are this year's most popular area rug styles. Update your home for the holidays, or give a gift that's a treat for the feet.
Tips on Buying a Persian Rug
Tips on Buying a Persian Rug from Overstock.com. Add classic elegance and rich texture to your home with a Persian rug. Here's what you need to know when you're online shopping for Persian area rugs.
Sole Redemption - 5 Rugs to Make Your Feet Feel Good
Sole Redemption: 5 Rugs to Make Your Feet Feel Good from Overstock.com. Having the right area rug underfoot can activate energy zones throughout your body.
Tips on Buying Outdoor Rugs
Tips on Buying Outdoor Rugs from Overstock.com. Here's how to choose the outdoor rugs that are perfect for your home. Complete your patio or deck and save money on the outdoor area rug that's just your style.
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"The texture was so velvety and the flavor was incredible. I'll definitely make this again!" – Mike B
"We loved everything about this chowder—from the fresh veggies to the tortellini to the creamy broth!" – Molly
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Delicata Creamy Squash Soup
Roasted squash lends a delicate sweetness to this creamy soup. Onions, chicken stock, and roasted squash are processed to a fine consistency, then combined with heavy cream, creating a heavenly smooth soup.
Sue Haser
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My ex fiance and I bought a mobile home together. We both signed as buyers. He took the title to get transfered, he came back and told me that he transfered it to his name only because I was not there to sign additional paperwork. The title came back in was in his name only. I started doing some research and found out that he forged my name in order to gain sole ownership. I talked with a lawyer who told me that the mobile home is his because he paid for it. Is this true?
Lawsuit / Dispute Attorney
Title usually follows payment
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If he paid for it, it is his.
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Victoria's Secret Stores Seasonal Sales Associate Interview Questions
Interview Experience
Interview Experience
Getting an Interview
Getting an Interview
Interview Difficulty
Interviews for Top Jobs at Victoria's Secret Stores
- Sales Associate (374)
- Sales Associate/Cashier (51)
- Seasonal Sales Associate (33)
- Sales Support Associate (28)
- Cashier (28)
- Bra Specialist (14)
- Store Manager (13)
- PINK Sales Associate (12)
- Stock Associate (11)
- Cash Wrap (9)
- Sales Specialist (6)
- Retail Sales Associate (6)
- Category Manager (6)
- Sales Representative (5)
- Sales Support (5)
- Stock (5)
- Intimates Category Manager (5)
- Operations and Staffing Supervisor (5)
- Cashier/Lingerie Sales Associate (4)
- PINK Campus Representative (4)
- Associate (4)
- Co-Manager (4)
- Customer Service Representative (4)
- Product Manager (4)
- Merchandise Flow Supervisor (4)
- Category Supervisor (3)
- Manager (3)
- Brand Delivery and Operations Manager (3)
- Sale Associate (3)
- Campus Representative (3)
33 Candidate Interview Reviews Back to all InterviewsSort: Popular Date Difficulty
Seasonal Sales Associate Interview
I applied in-person. The process took 2 weeks – interviewed at Victoria's Secret Stores (Allen, TX).
Group interview with 2 other girls. It was very relaxed and the manager was really cool. Ordinary interview questions like why I want to work there. She did throw in 1 out of the box question but it was interesting and made it fun . The whole process for the the group only took about 30 minutes. Easy interview.
Interview Questions
- If you were to pick one animal to represent your traits/personality, what would it be? Answer Question
Other Interview Reviews for Victoria's Secret Stores
Seasonal Sales Associate InterviewNo OfferPositive ExperienceAverage Interview
I applied in-person. The process took 3 weeks – interviewed at Victoria's Secret Stores (Fairview Heights, IL) in May 2015.
Group interview, great manager, it took a week for them to call to set up interview. Haven't received word on whether I got the job, its been a little over a week.
Interview Questions
- Whats your favorite VS product Answer Question
Seasonal Sales Associate InterviewAccepted OfferNegative ExperienceDifficult Interview
I applied in-person. The process took 2 weeks – interviewed at Victoria's Secret Stores (San Diego, CA) in May 2015.
Three interview process.
One interview with the hiring manager. One with the manager for the area you are interested (I interviewed with the beauty manager). And, one with the store manager.
First interview is a group interview with 2 other applicants. Second and third interview are one-on-one.
First interview took ~1 hr, second and third ~30 mins.
Interview Questions
- How can beauty be related to selling bra, which is what Victoria's Secret known for? 1 Answer
Seasonal Sales Associate InterviewAccepted OfferPositive ExperienceEasy Interview
I applied in-person. The process took a week – interviewed at Victoria's Secret Stores (Evansville, IN) in May 2015.
Pretty laid-back interview. Submitted an application in person and was contacted about a week later for an interview. The interview itself was a group interview with two other people. I had looked on this app for potential questions, and several came up that I'd seen before. However, I second-guessed myself and didn't answer the question about "wardobing" a customer for fear of being wrong-wish I had spoken up. Don't be afraid to hold conversation with the interviewer! We all took turns answering the questions for the most part, but don't be afraid to share real-life experiences you've had in the store or other stores, even if it is an example of something negative that you've learned from. The people at this location are all very nice and seem to be very close to each other. I received a call with a job offer the day after the interview.
Interview Questions
- What does it mean to "wardrobe" a customer? 1 Answer
- What is the first thing you notice when you enter a store? 1 Answer
- Have you ever mentored anybody? Describe the experience. 1 Answer
- What is a current fashion icon whose style you admire? 1 Answer
- Do you have any personal favorite prod it's from Victoria's Secret or PINK? 1 Answer
Helpful (5)
Seasonal Sales Associate InterviewAccepted OfferPositive ExperienceAverage Interview
I applied in-person – interviewed at Victoria's Secret Stores (Culver City, CA).
It was a group interview with about five or six other people applying and it lasted about 30 minutes total. We met outside the store in the mall so it was fairly casual. The interview was conducted by the store manager and she asked us 4 or 5 questions each, sometimes the same questions, sometimes different. Out of the six or seven of us, four or five of us were offered positions.
Interview Questions
- How would you make the link between our lingerie and beauty sections? 1 Answer
- What position do you think you would be best at and why? Answer Question
Seasonal Sales Associate InterviewNo OfferNeutral ExperienceAverage Interview
I applied in-person. The process took 2 days – interviewed at Victoria's Secret Stores (Little Canada, ME).
Very easy and friendly interview. Basic retails questions. Applied during job fair and got scheduled for a group interview. Was interviewed by two category manager. After interview was over was told that we would be hiring within a week and if we didn't then they have our files for 6 months. No unexpected questions everything was typical questions about yourself or work background.
Interview Questions
- Why should we hire you? Answer Question
Seasonal Sales Associate InterviewAccepted OfferPositive ExperienceEasy Interview
I applied in-person. The process took 2+ months – interviewed at Victoria's Secret Stores (Las Vegas, NV) in November 2014.
Turned in an application and wasn't contacted for about two months, but I received a call to come to a group interview. The interview was with one of the assistant store managers in the operations department and she asked basic questions like why do you want to work for us, what department would you like to work in and why, job history, etc. She said we would be contacted by the category manager for the department we wanted to work in if we made the cut. A few days later the PINK manager called me and set up a 1:1 interview. She basically told me to just talk about my previous experience within the company since I would be a rehire and what track I would prefer to follow (bras, sales/apparel, etc) and it was very much just a conversational "interview". She said my references would be checked and I would be called in a few days if they check out. THEY ACTUALLY CHECKED ONE OF MY REFERENCES! I've never had that happen before, it's good that they follow up. I received an offer to start as seasonal and if I want to stay after holiday (performance depending) then I can.
Interview Questions
- What was my least favorite thing about my favorite job? Answer Question
I was told the seasonal pay rate was set, but if I'm kept on as a regular employee I would be given a raise.
Helpful (3)
Seasonal Sales Associate InterviewAccepted OfferPositive ExperienceEasy Interview
I applied in-person. The process took a week – interviewed at Victoria's Secret Stores in October 2014.
Saw an ad online. I downloaded an app filled it out and handed it in along with a resume and cover letter to a store employee. Got a call two days later to schedule an interview. I would HIGHLY suggest you write a cover letter detailing your job experience, skills, and knowledge of the brand (or what you own).
The interview was scheduled two days after phone call. I met 1-on-1 with the manager and sat in her office to briefly discuss a little about myself and basically why she should hire me. You should emphasize sales/customer service skills and how you would assist a customer.
I came prepared, eager, and the interview literally was 5 minutes because she had to go back to work and they needed people ASAP.
Make sure you also have good references because they will check them!
Interview Questions
- Something along the lines of: how would you handle a customer who's feels uncomfortable in the store (maybe someone body conscious)? Answer Question
$8.50, no negotiation. You work your way up!
Seasonal Sales Associate InterviewNo OfferNeutral ExperienceAverage Interview
I applied in-person. The process took 2 days – interviewed at Victoria's Secret Stores (Montclair, CA) in September 2014.
I walked in and filled out a resume and i turned it in to the manager, she asked me questions on the spot, why do you want to work here, etc. The the next day I received a call for a group interview, which was just myself and another lady. It was very odd given that it was taken place at the food court, but the manager, Rene just asked questions, rather easy, and when we were done she said to expect a call in a week for a following interview, and after that possibly be hired.
Interview Questions
- What comes to your mind when you hear 'the customer rule" Answer Question
Seasonal Sales Associate InterviewAccepted OfferPositive ExperienceEasy Interview
I applied in-person. The process took 4+ weeks – interviewed at Victoria's Secret Stores (San Diego, CA) in September 2014.
I went in to give them my resume and they had me fill out an application. Super quick and the every day type of applications. I ran back in to hand it in and spoke to a manager. She looked over my resume and application and noticed I had experience in retail and then told me she would be calling me to schedule an interview. Two weeks later she called to schedule an interview three days later. I came for my interview and there were only 2 other girls in my group interview. The interview was with the store manager who was absolutely amazing. The interview was just trying to find out about who we were and why we wanted to work here. We were told we would get a call to schedule a second group interview because she knew she wanted us. A few days later we were called to set up the second interview. Again, it was just the three of us and a different manager. She also tried to find out who we were and what we wanted to do. A week and a half later I got the call asking me to join them. I accepted of course! They had us do two days of onboarding ( getting to know the policies and company), two days of shadowing, and then you were off to work for this great company. Oh and they DO check on who you put down on your references- they will call them and make a list of what they said about you!
Interview Questions
- What defines excellent customer service? 1 Answer
- What is your favorite VS bra and why? 1 Answer
- Describe a time you had to deal with a fast paced environment with a lot of people needing help and how you managed to help them and remain calm and collected. Answer Question
- How do you deal with stress? Answer Question
I wasn't able to negotiate, but she offered me fifty cents more an hour than my other jobs so I easily accepted.
Is this helpful? The community relies on everyone sharing – Add Anonymous Interview Review


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about Todd FlowerdayA Roman Catholic lay person, married (since 1996), with one adopted child (since 2001). I serve in worship and spiritual life in a midwestern university parish.
about John Donaghy
John is a lay missionary since 2007 with a parish in western Honduras. Before that he served in campus ministry and social justice ministry in Iowa. His ministry blog is http://hermanojuancito.blogspot.com
He also blogs reflections on the lectionary and saints/heroes/events of the date at http://walktheway.wordpress.com
He'll be a long-term contributor here analyzing the Latin American bishops' document from their 2007 Aparecida Conference.
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Tag Archives: Cardinal Law
'He is not to come to this church any more.'
The various news reports surrounding the new pope are entertaining. Does he have one lung or two? Was he soft on South American fascism? I like this one: Cardinal Law ejected from Santa Maria Maggiore. So hearing that the new … Continue reading
Posted in bishops, sex abuse Tagged Bishop Finn, Cardinal Law, pope francis 11 Comments


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Inflammation and its associated pathologies are increasingly suggested as risk factors for colorectal cancer (CRC) development. Previous research from our group has shown that increased levels of circulating, pro-inflammatory cytokines IL-6 and TNFα promote colorectal adenoma risk. Emerging data in mice and humans suggest that Suppressor of Cytokine Signaling 3 (SOCS3) may act as a tumor suppressor in the intestine, and decreased SOCS3 expression may promote CRC. As SOCS3 has been shown to inhibit the actions of IL-6 and TNFα in the intestine, we hypothesized that decreased SOCS3 expression in normal mucosa may predispose to adenomas and thus increase risk for CRC.
We examined SOCS3 mRNA levels in normal mucosa biopsies of 322 screening colonoscopy patients (93 with adenoma and 229 without adenoma) using real-time qRT-PCR. Logistic regression analysis was used to generate odds ratios (OR) and 95% confidence intervals to determine if low SOCS3 expression was associated with adenoma status. Median SOCS3 values did not differ between patients with or without adenoma. Logistic regression analysis showed no association (unadjusted or adjusted for age and sex) between SOCS3 and colorectal adenomas.
Low SOCS3 mRNA expression is not an independent biomarker of colorectal adenoma risk in the normal mucosa. SOCS3 silencing likely occurs later in CRC progression.
Recent evidence in mice and humans suggest that the anti-inflammatory protein Suppressor of Cytokine Signaling 3 (SOCS3) may act as a tumor suppressor in the colon [1,2]. Specific silencing of SOCS3 expression in intestinal epithelial cells (IEC) increased tumor load in the azoxymethane/dextran sodium sulfate (AOM/DSS) mouse model of inflammation-associated CRC [1]. Furthermore, SOCS3 expression is low or silenced by promoter hyper-methylation in other cancers, including lung, liver, and squamous cell carcinoma [3-5].
Prior studies from our group demonstrated that increased systemic levels of pro-inflammatory cytokines IL-6 and TNFα correlate with risk of colorectal adenoma [6]. SOCS3 has been shown to limit the actions of both of these cytokines as well as their downstream targets STAT3 and NFκB, which are frequently activated in humans and mouse models of CRC [2,7-12]. Based on these studies, we investigated SOCS3 mRNA expression in the normal mucosa of patients undergoing routine screening colonoscopy to determine if low SOCS3 predisposes to adenoma and could thus be considered an early biomarker of CRC risk.
Materials and methods
Study Population and Data Collection
All eligible subjects provided written, informed consent. Consenting participants were enrolled in Diet and Health Study IV at University of North Carolina Hospitals as previously described [13]. Briefly, subjects undergoing routine colonoscopy provided rectal biopsies and blood samples for the study. Subjects also consented to follow-up interview to collect diet and lifestyle information. High quality RNA from 322 subjects (93 with adenoma, 229 without adenoma) with complete information on plasma IL-6 and TNFα, age, race, sex, waist hip ratio (WHR), family history and non-steroidal anti-inflammatory drug (NSAID) use was assayed for SOCS3. Patients in the adenoma group were defined as having one or more adenomas by the study pathologist based on standard criteria. The study was approved by the University of North Carolina School of Medicine Institutional Review Board.
RNA Extraction and Real-Time qRT-PCR
RNA from four pooled, normal colon biopsies per subject was extracted using Qiagen's RNeasy kit (Valencia, CA) and reverse transcribed with AMV-Reverse Transcriptase (Promega) as previously described [13].
SOCS3 mRNA abundance was determined using the ABI Prism 7900 HT (Applied Biosystems, Foster City, CA) and Platinum Quantitative PCR SuperMix-UDG (Invitrogen, Carlsbad, CA). Human SOCS3 (NM_003955.3) was quantified using Applied Biosystem primer/probe set targeting exon 2. The housekeeping gene hydroxymethylbilane synthase (HMBS, NM_000190.3) was chosen as a low-abundance, invariant control. Standard curves for each primer/probe set were generated using gel-isolated, sequence-confirmed PCR products. Cycling included initial denaturation at 95°C for 5 minutes followed by 45 cycles of 95°C denaturation for 15 seconds and 60°C annealing for 45 seconds. Threshold cycles analysis was performed using Applied Biosystem SDS v2.2.2 software and values are expressed as copy number relative to HMBS. All PCR runs included standards and inter-run calibrator controls (pooled sample cDNA), as well as non-reverse transcribed (no-RT) and water controls. Samples were run in triplicate.
Statistical Analysis
Means and standard errors were generated for continuous variables, and frequencies and percentages were generated for categorical variables. T-tests and Mann-Whitney tests were used to compare cases with controls on continuous variables. SOCS3 values were log-transformed to normalize the distribution. Chi-Square tests were used to compare cases and controls on categorical variables. Logistic regression was used to test for an association between case/control status and SOCS3. Levels of SOCS3 were categorized into tertiles based on control values. Age, race, sex, WHR, NSAIDS, IL-6, TNFα, and family history were assessed as potential confounders of SOCS3-adenoma association. Each variable was put into a model separately with SOCS3, and if one of the two dummy variables for SOCS3 changed by at least 15% compared to when only SOCS3 was in the model, then that co-variable passed the first stage for being a confounder. All such variables were then entered into a model with SOCS3 and a backwards, stepwise regression was done with the SOCS3 variable being forced into the model. Only age and sex met these criteria for confounding and thus they were included in the final model.
Descriptive characteristics of the population in the SOCS3-adenoma study are shown in Table 1. Consistent with results from our prior reports for the study population, subjects with adenomas were older, more likely to be male, had higher waist-hip ratios and increased plasma IL-6 [6,13]. There was no difference in median SOCS3 between individuals with or without adenoma.
Table 1. Descriptive Characteristics of Study Participants
To determine if low SOCS3 is associated with having an adenoma, odds ratios and 95% confidence intervals were generated using logistic regression analysis (Table 2). There was no difference in odds ratios in subjects in the lower tertiles of SOCS3 values, indicating that low levels of local SOCS3 expression do not associate with adenoma risk.
Table 2. Adjusted Association Between Local SOCS3 Levels and Adenoma
Identifying local factors that predispose patients to early, pre-cancerous lesions may make it possible to stratify screening based on risk, but risk factors that occur early in CRC development are not well defined. Our group has shown that patients with adenoma have reduced apoptosis in their normal mucosa, demonstrating a field effect that predisposes the individual to a higher risk of developing precancerous adenomas [14,15]. We hypothesized that SOCS3 might be a good biomarker of colorectal neoplasia risk, but contrary to expectation the study was negative.
Patients with inflammatory bowel diseases (Crohn's disease or ulcerative colitis) have an increased risk of developing CRC, which is associated with the degree and duration of intestinal inflammation (reviewed in [16]). In addition, recent data suggest that individuals with chronic, low levels of inflammation (such as increased circulating IL-6 and TNFα) have increased odds of having adenoma and thus increased CRC risk [6]. SOCS3 is an anti-inflammatory protein that limits IL-6 induction of STAT3, as well as TNFα induction of NFκB. IEC-specific silencing of SOCS3 leads to a dramatic increase in tumor load in a mouse model of inflammation-associated CRC [1]. Furthermore, recent studies show that STAT3 activation is increased, and SOCS3 is silenced in tumors of patients with ulcerative colitis-associated and sporadic CRC [2,17]. The current study tested the hypothesis that patients with adenoma may have lower SOCS3 in the normal mucosa than patients without adenoma, thus contributing to a permissive environment for aberrant growth. However, our study found that low or silenced SOCS3 expression does not occur in the normal mucosa of patients with colorectal adenoma.
One potential limitation of the study is possible effect of standard bowel preparation on SOCS3 expression. While we have not directly tested this for SOCS3, similar studies of other genes have shown that there is no significant change in mucosal gene expression in patients using bisacodyl or polyethylene glycol bowel preparations [18]. Another possible limitation is that SOCS3 mRNA levels do not reflect changes in SOCS3 phosphorylation, which leads to its targeting for proteasomal degradation [19]. However, other studies show that SOCS3 is silenced by DNA hyper-methylation in CRC tumors [2], indicating that evaluating changes in gene expression is an appropriate measure of SOCS3 in this study. Finally, while our results could indicate that SOCS3 is more important in the underlying pathogenesis of inflammation-associated rather than sporadic CRC, recent studies comparing SOCS3 expression in both ulcerative colitis-associated and sporadic tumors found that SOCS3 was decreased and there was no significant difference between the two groups for SOCS3 [2]. Taken together with these studies, we conclude that SOCS3 silencing occurs later in the progression from adenoma to adenocarcinoma, and is not an independent, early biomarker of CRC risk in the normal mucosa.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
KEH carried out the molecular studies, participated in data analyses, and drafted the manuscript. PKL and RSS participated in the study conception, design, and coordination. JAG performed the statistical analyses. TOK participated in the study conception, design, and coordination, and helped to draft the manuscript. All authors read and approved the final manuscript.
The authors would like to acknowledge Lauren Parker for technical support. The studies and preparation of this manuscript was funded by NIH grants R01 CA044684 and P30 DK034987. KEH is partially supported by the HHMI Med-Into-Grad-funded UNC Program in Translational Medicine.
Rigby RJ, Simmons JG, Greenhalgh CJ, Alexander WS, Lund PK: Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon.
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Gut 59:227-235. PubMed Abstract | Publisher Full Text
He B, You L, Uematsu K, Zang K, Xu Z, Lee AY, Costello JF, McCormick F, Jablons DM: SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer.
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Oncogene 2005, 24:6406-6417. PubMed Abstract | Publisher Full Text
Weber A, Hengge UR, Bardenheuer W, Tischoff I, Sommerer F, Markwarth A, Dietz A, Wittekind C, Tannapfel A: SOCS-3 is frequently methylated in head and neck squamous cell carcinoma and its precursor lesions and causes growth inhibition.
Oncogene 2005, 24:6699-6708. PubMed Abstract | Publisher Full Text
Kim S, Keku TO, Martin C, Galanko J, Woosley JT, Schroeder JC, Satia JA, Halabi S, Sandler RS: Circulating levels of inflammatory cytokines and risk of colorectal adenomas.
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Suzuki A, Hanada T, Mitsuyama K, Yoshida T, Kamizono S, Hoshino T, Kubo M, Yamashita A, Okabe M, Takeda K, et al.: CIS3/SOCS3/SSI3 Plays a Negative Regulatory Role in STAT3 Activation and Intestinal Inflammation.
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Wang L, Walia B, Evans J, Gewirtz AT, Merlin D, Sitaraman SV: IL-6 Induces NF-kB Activation in the Intestinal Epithelia.
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Why Doesn't Iran Want the Bomb?
When adding up the potential benefits and impediments, Iran will unlikely upgrade its current civilian nuclear programme to a military nuclear weapons programme.
When adding up the potential benefits and impediments, Iran will unlikely upgrade its current civilian nuclear programme to a military nuclear weapons programme.
This is an exciting time for the entirety of human civilization, it is important for all parties in the planning of the forthcoming human expansion into outer space.
Sino–Russian relations are better today than at any point throughout their troubled history, due to the structure of the inter-state system and domestic factors.
Depicting how certain assumptions are constructed, constructivism is useful to unveil that the security threat of migration is socially produced.
The extent to which social forces influenced the overhaul of Iranian society presents an advantageous case study which social constructivism can explain.
Negative attitudes towards the United States are generally specific to foreign policy choices rather than a broader statement about American culture or society.
The three levels of analysis can explain why contention can emerge when political issues are securitized such as the securitization of the Iraqi regime and US invasion.
Although states can construct meaningful bonds between each other, these are better conceptualised as partnerships, not friendships. State relations are not friendships.
Addressing Kofi Annan's question in traditional Liberal terms is but one way, of many, to phrase the Responsibility to Protect debate.
Geographical knowledge can be politicized, such that maps are techniques of power, representing a manipulated and politically-charged discourse about the world.
UN Resolution 1325, although not yet a complete success, can and should be used as a starting point to work for gender equity and towards a violence-free world.
By examining the European Union's engagement with China on climate change, the EU could arguably be a credible normative power on climate change policy.


text:
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As the search continues for low-cost and high-performance components for the front-end devices for wireless communications systems, some focus has been placed on exploring new and innovative designs based on ferroelectric technology. In this paper, we present new phase-shifter designs and an integrated phased-array antenna system based on the use of multilayer ferroelectric materials and the continuous transverse stub (CTS) technologies. Simulation results show that with the appropriate selection of the materials properties and the dimensions of the multilayer dielectric system, insertion losses may be reduced by as much as a factor of 100. These results also show that while only a slight reduction (15%) in the maximum achievable tunability was observed, it was possible to achieve significant improvement in impedance-matching characteristics. A procedure to enhance the radiation efficiency from an integrated ferroelectric/CTS phased antenna array design is described and specific array designs are discussed


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(7) Preschools
(4) Preschools
There are 9 private schools located in Utah that offer Baseball as an interscholastic sport.
Since 1982, Rowmark Ski Academy has offered a year-round ski-racing program coupled with an extraordinary high school. Our goal is simple: to deliver the best possible program to identify, develop, and help every one of our elite scholar-athletes realize their potential on the race course and in the classroom.
At Blessed Sacrament, the Interfaith Meditation Garden is used for prayer, study, sketching, thinking and resting. This garden is used by students as well as community members, and offers a stunning view of the Wasatch Mountains.
Music Room-ICS offers Bell Choir, Concert Band, Jazz Band, Worship/Chapel Band, Pep Band, Ensemble, Elementary music programs & 5th Grade Band. Yearly music tour for bell choir & ensemble-travel to New Mexico and Arizona to minister at the mission schools.
Baseball Private Schools
- School Location Students Grades
Mount Pleasant Wasatch Academy
Mount Pleasant, UT 84647
(435)462-1400312 students | Gr. 8-12
SandyBlessed Sacrament School
1745 East 9800 South
Sandy, UT 84092
(801)572-5311(Roman Catholic)264 students | Gr. PK-8
RivertonConcordia Preparatory School12723 S Park Avenue
Riverton, UT 84065
(801)878-1515(Lutheran Church -- Missouri Synod)30 students | Gr. 7-12
Salt Lake CityIntermountain Christian School
6515 Lion Lane
Salt Lake City, UT 84121
(801)365-0370(Christian)284 students | Gr. NS-12
DraperJuan Diego Catholic High School
300 East 11800 South
Draper, UT 84020
(801)984-7661(Roman Catholic)818 students | Gr. 9-12
Salt Lake CityJudge Memorial Catholic High School
650 South 1100 East
Salt Lake City, UT 84102
(801)363-8895(Roman Catholic)726 students | Gr. 9-12
LaytonLayton Christian Academy
2352 E Highway 193
Layton, UT 84040
(807)771-7141(Christian)464 students | Gr. PK-12
Salt Lake CityMount Vernon Academy
184 E Vine Street
Salt Lake City, UT 84107
(801)266-5521119 students | Gr. K-12
Salt Lake CityRowland Hall
720 Guardsman Way and 843 S Lincoln Street
Salt Lake City, UT 84108
(801)355-7485908 students | Gr. NS-12
State Statistics
|About This State (UT)
|(UT) State Statistics
|Nationwide Statistics
|Population (Approximate)
|2,623,840 people
|304,788,332 people
|Age 25+ w/College Degree
|Median Household Income
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