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MySQL Introduction
We have no intention of stopping development of MySQL. Over time, MySQL will be 100% ANSI 92 compatible. As we still want MySQL to be fast, we will always give the user the option of specifying the removal of features which make a normal SQL server slow.
As an example, the GRANT system will not have any speed impact unless you use this to restrict table or column access.
The current "TODO" list can be found in the MySQL manual at www.mysql.com/doc.html. Everything in this list is in the order we plan to implement it.
We have worked many years with GNU/BSD and other programs from the Net and have always believed that programs should be available in source. Because of this, we chose to use the same license as Aladdin GhostScript for the MySQL server on UNIX, and we made the client's completely free.
By the time this article reaches publication, there should be an old version of MySQL (3.20) with a GPL copyright available. We will continue releasing old versions under the GPL.
This means that for normal (even commercial) internal use on UNIX systems, MySQL costs nothing. You do not have to pay us if you do not want to. A license is required only if:
You sell the MySQL server directly or as a part of another product or service.
You charge for installing and maintaining a MySQL server at some client's site.
You include MySQL in a distribution that is non-redistributable, and you charge for some part of that distribution.
You use MySQL on a Win32 (Windows 95, 98, NT or Windows 2000) system.
For circumstances under which a MySQL license is required, you need a license per machine that runs the mysqld server. However, a multiple-CPU machine needs only one license, and there is no restriction on the number of MySQL servers that can run on one machine, or on the number of clients concurrently connected to a server running on that machine.
The following points set forth the philosophy behind our licensing policy:
The SQL client library should be totally free so that it can be included in commercial products without limitation.
People who want free access to the software into which we have put much work can have it, as long as they do not try to make money directly by distributing it for profit.
People who want the right to keep their own software proprietary, but also want the value from our work, can pay for the privilege.
That means normal in-house use is free. But if you use MySQL for something important to you, you may want to help further its development by purchasing a support contract or by contributing documentation, code samples or something else.
Our policy is that no one should have to pay for normal upgrades. In the future, we may require a new license for major upgrades with major new features (like transaction support). This means that in the long run, MySQL will be a very good investment compared to other databases.
As Win32 is a highly commercial OS with very high development costs (and development pains), we see no other alternative than to provide MySQL-Win32 only to paying customers, users who have helped us with MySQL in some way or users who think they can contribute to any part of MySQL. If we did this in any other way, we could not afford to continue developing MySQL on Win32 or even keep this version up to date with the UNIX version. In effect, we let users who run Win32 pay for the development of tools of our other operating systems.
David Axmark (firstname.lastname@example.com) lives in Uppsala, Sweden with his plants and computers. He has been working as a software consultant for over 15 years.
Michael Widenius lives in Helsingfors, Finland with his wife and his two kids My and Max. He also has been working as a software consultant for over 15 years.
Among the things both authors have worked with are software for a one-card computer used by power companies, a video-rental system, a state-of-the-art market research system, advanced business graphics, a word processor that could handle Z80 Assembler+Basic, and a full operating system for an 8-bit computer (Z80) and many other other projects.
Re: MySQL Introduction
This articels is useful for plaing to use MySql database.
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It's that time of the year again… (…) Read more »
Tagged: vintage
Event Decor Advice From The Experts At PatinaSep 26, 2014
Wrapping up our coverage of our End of Summer Rooftop Party, today we wanted to highlight the decor gurus of Patina. Based in Brooklyn and run by Corrin Arasa, a self-proclaimed "design addicted furniture junkie," Patina provided the beautiful long table, mismatched vintage chairs, and wood bars that made the decor at our event so (…) Read more »
Love What You Do: Humboldt HouseAug 22, 2014
Take one woman, an idea, and a lot of hard work, and the outcome is a seed turned into the fullest flower. (…) Read more »
About A Girl: Ruthie LindseyAug 21, 2014
Certain people come into our lives, and even in the fleeting moments that we spend with them, they affect us so profoundly that they leave a lasting mark on our hearts. Ruthie Lindsey is one of those people. (…) Read more »
Love What You Do: Harold & ModAug 17, 2014
Meet Milo Beloved, owner of the sweet Birmingham vintage store Harold & Mod. While we were in town for our River Rose and FP Me shoots, we couldn't resist the opportunity to sit down with Milo and hear about the inspiration behind his business and how he turned his fantasy into reality. There is such (…) Read more »
Our Vintage Buyer Shares Her Top 5 Favorite PiecesAug 05, 2014
I've had a love for vintage ever since my mother first allowed me to dig through boxes of her old clothes all those years ago. (…) Read more »
Lost Girls Vintage at Antique TacoJul 24, 2014
Take two rad girls, an awesome collection of vintage, a 1976 RV, and that ladies and gentlemen, is Lost Girls Vintage. (…) Read more »
A Love Of Vintage BooksJun 12, 2014
My love of books was instilled in me at a young age. (…) Read more »
Sheer Romance: 5 Vintage FavoritesFeb 26, 2014
Sheer Romance is the name of our newest Vintage Loves collection, and it's all about straps, lace, and sheer fabrics coming together to create a beautifully romantic look. Our vintage buyer, Ali, is incredibly well-versed when it comes to the world of all things vintage, and I always love to hear her take on the (…) Read more »
Vintage Loves Is Back: Sheer RomanceFeb 21, 2014
For our latest collection of Vintage Loves, Sheer Romance, our vintage buyer Ali traveled across the country, seeking rare, ultra-femme silhouettes in whimsical whites and soft blush tones. Carrying with them the stories of decades past, these pieces prove that no love is ever lost. While shooting one of our styling stories (Locals Only) last (…) Read more »
Vintage Decor HeavenJan 29, 2014
Vintage decor. These words together make my heart flutter in an instant — they always have. There's just something so alluring about the way things were. (…) Read more »
Rose Bowl Flea Market: Street StyleDec 19, 2013
Fancy some of the very best people watching LA has to offer? Put this in your calendar. The second Sunday of every month, up to 20,000 people roll in to shop and sort the 2,500 booths of vintage, furniture, antiques, textiles (and much more) of the Rose Bowl Flea Market. Designers, celebrities, stylists, interior decorators… LA's (…) Read more »

subset: commoncrawl


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This engaging story tells how a brave Native American female became a legendary Crow chief. Born in 1800, Pine Leaf longed to be a hunter who rode with the tribe's males instead of learning how to be a lodge woman. As she grew she stubbornly proved that she could ride, hunt and fight with the best. She fulfilled her dreams of leading warriors into battle in the land later called Montana and Wyoming.
In the late 1700s, Ed Rose earned his facial scars
in a bar fight in Kentucky. His travels and search for adventure led him to the plains east of the Rocky Mountains. Rose, a guide, interpreter and trader, hunted and fought alongside the Crow, the Arikara, white trappers and explorers and the US Army. He rode with the Crow hunters who captured the girl who became Woman War Chief.
The battle for Texas was fought on many fronts. This book centers on the efforts of the Comanche to maintain their way of life, the homesteading adventures of the Parkers, and the task of the Texas Rangers to protect Texas settlers from raids. In 1836 Comanche captured a white girl from the Parker fort; decades later her son, Quanah Parker, was one of the last Comanche to surrender at Fort Sill.
Running Eagle was born near the Rocky Mountains in the late 1700s. With her tribe she hunted for food and fought enemy tribes; she was praised for her bravery. She often stole horses from other tribes and is remembered for her vision quest to a waterfall named after her.
This book explores the traditions of her people, along with the threat they faced from encroaching fur trappers.
This entertaining memoir contains a hundred stories about the Matney boys, four brothers who found creative ways to have fun in the land around Big Sandy Creek. From the 1930s to the 1950s, these boys and their friends often skirted danger and the law. Stories range from intimate to hilarious to frightening as the growing boys learn to live alongside cows and dogs while constantly trying to outdo each other.
Coming Soon!
Jerry Matney has written four historical novels set in the American West, each centered around
Native American historical figures. He has also written a childhood memoir and the story of a character named Shanghai. His books are available as eBooks from Amazon and other online vendors. To purchase a Print copy, contact Jerry at: email@example.com
© 2012 - 2015 by J A Matney | webmaster: D A Gordon


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In This Section
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Clean Audio for TV broadcast: An Object-Based Approach for Hearing-Impaired Viewers - April 2015
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Audibility of a CD-Standard A/DA/A Loop Inserted into High-Resolution Audio Playback - September 2007
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Sound Board: Food for Thought, Aesthetics in Orchestra Recording - April 2015
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AES Convention Papers Forum
Recording History in Audio Education
This research will discuss the state of history education for the audio recording field. As the audio industry evolves, it is becoming more apparent that its history, for purposes of teaching, is rather unorganized. Also, on the whole, students learning the practice of audio recording are not being well educated in its history. As a result, students studying to become audio experts are not gaining awareness of a fundamental aspect of the field. This report surveys experiences and viewpoints of professionals, highlights existing recording history in audio education, and explores methods for audio history pedagogy. In addition, a suggested framework of historical periods of audio is presented and a concise list of resources is suggested.
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Overheated outlet blamed for Newport fire
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Overheated outlet blamed for Newport fire
An overheated electrical outlet that powered an air conditioner is being cited as the cause of a residential fire Sunday afternoon in Newport, Newport Fire Capt. Randy Childress said Monday.
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Title shot on the line for Hendricks
MMA gear now available at the UG Store
tags: Johnny Hendricks UFC on FOX 3
Recent Comments »
5/6/12 3:12 AM by xsrg95
5/3/12 10:02 PM by lgi
What are some examples of exciting fighters playing it safe when promised a title shot?
5/3/12 7:40 PM by Masakatsu Funaki
5/3/12 12:31 AM by Krs10KO.com
^^ holy crap that made me laugh.
5/2/12 11:17 PM by Floppy Divac
What a stupid fucking thing to say Dana.
5/2/12 11:15 PM by UGCTT_SidRival
Against who? Not that I think he'll win but if he does they should certainly make Condit defend.
5/2/12 10:37 PM by FedorEmilioEstevez
I agree with you
5/2/12 10:36 PM by newjack900
Why would Dana say this when he knows damn well the winner of this fight will have to fight the winner of Kampman v ellenberger and there would still probably be a wait on the winner of GSP v Condit. Hyperbole for the Fox card at its finest.
5/2/12 10:06 PM by Fawkinxd
so i kind of don't understandwho really get's the title shot hendricks, ellenbarger/kampman, or condit? are they going to jump gsp for the title?is it falls count any where triple threat match? or are there going to be two titles at WW?didn't ellenberger vs kampman get guaranteed to be numero uno contender? or is it like number one contender match?
5/2/12 9:51 PM by fsshariq
It seems like the WW division is starting to get bottlenecked at the top, just like the LW division.


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By: Gini Dietrich | July 12, 2011 |
Up at 5 a.m. Check email, Facebook, Twitter, G+, LinkedIn groups and discussions, text messages, blog traffic, web traffic, and PostRank analytics all while brushing your teeth and feeding kids or pets. Make time to exercise, do some writing, get ready for work. Work a full day. Rush home to make and have dinner with your family. Check email, Facebook, Twitter, G+, LinkedIn groups and discussions, text messages, blog traffic, web [&hellip... Read More
By: Gini Dietrich | July 11, 2011 |
Something weird is happening: We're the pretty girl who isn't getting invited to Prom because everyone assumes she's already been asked. In the past month, I have had three different people ask me if I can recommend a PR/digital firm. With all three I asked more about their needs (because I assumed they already disqualified us) only to realize we'd be a perfect fit for them. [&hellip... Read More
By: Arment Dietrich | June 29, 2011 |
One of my best friends is the manager for the Obesity Prevention Program for the State of Alaska. She has uncovered the secret to losing weight and has a FABULOUS idea for a book on the subject. It's called, Eat Less, Exercise More. The end. I know, it's a radical idea, and we laugh so hard every time we talk about it. And how huge this [&hellip... Read More
By: Gini Dietrich | June 28, 2011 |
This is not a blog post about PR or marketing. It's not a blog post about social media. It's not even a blog post about entrepreneurship or leadership. But it's a post about something I care deeply about so I hope you'll grant me a little leeway today... Read More
By: Gini Dietrich | June 22, 2011 |
Some of you may not know that I grew up in Utah. The inevitable question, after I tell people that is, "Are you Mormon?" Yes, I was raised Mormon. Through a series of family events and some hypocrisy with some of the members in our ward, I stopped going to church when I was 18, right before I graduated from high school. And then I went [&hellip... Read More
By: Gini Dietrich | June 16, 2011 |
It's Facebook question of the week time (clap, clap, clap)! This week, the question comes from Ryan Cox, who actually asked 10 questions about a month ago. I chose my favorite of the 10 to answer, but may answer others in coming weeks if you people don't get over to our wall and ask a question. Nancy Davis! I think we need the Louisville Slugger again! [&hellip... Read More
By: Guest | June 13, 2011 |
Jeannie Walters has been focused on the customer experience for more than 15 years, consulting to companies big and small on their retention strategies. She is principal at 360Connext, a speaker, and mom to two young boys. As humans, we like to fool ourselves. At best, it's a way to be kind to ourselves ("It's ok to eat this on vacation!") and at worst a way [&hellip... Read More
By: Gini Dietrich | June 12, 2011 |
eBooks are all the rage right now. Some are free and some come at a price. Having written and produced three (you can find "Dear CEO" and "Social Media Primer" by clicking here), I know how much work they are, both from a content standpoint and working with the eReader software so it can be delivered on your Kindle or Nook. Because of that, there are three [&hellip... Read More
By: Gini Dietrich | June 1, 2011 |
I'm looking at a blank screen this morning, wondering what I'm going to write about today. It's 6:06 am and inspiration hasn't hit yet. This is unusual. You see, what I really want to write about, what I really want to get out of my system, is how embarrassed I am at the uproar caused by Danny Brown and me having to change the title of [&hellip... Read More
By: Gini Dietrich | May 24, 2011 |
Yesterday I had a very frank conversation with a close friend. He was describing a situation where he felt like he had failed. You see, he tried this whole entrepreneur thing and he recently had to get a full-time job. He had to go back working for the man; being an employee. And, in his mind, he failed. We talked about how hard entrepreneurship is: Not [&hellip... Read More


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A scrolling social sharebar scrolling plugin with 7 social icons (Twitter, FB Like, Google +1, Linkedin, FB Share, Stumbleupon and Addthis) and option
After I disabled this plugin then all the server 500 errors which were only on about 1 in 5 posts were gone. When I re-enabled then they all came back. So this plugin has the ability to wreck a site.
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Italian Open Championship 2014
Italian Open Championship 2014 Rimini, Italy - 27-29.06.2014 Dance Portal MostDance.com | http://ballroom.mostdance.com...
- published: 21 Jul 2014
- views: 2
Rome, May 15 (IANS) World No. 1 Serena Williams beat Andrea Petkovic 6-2, 6-2 in the second round of the Italian Open Wednesday to march on for a possible semi-final collision with Maria Sharapova. Williams showed no ill effects of the left...Newstrack India 2014-05-15
The grace and glamour of Italian fashion are on display in London — and the attitude, too. Designers Domenico Dolce and Stefano Gabbana were guests at the launch of "The...U~T San Diego 2014-04-02
The following is a list prize money up for grabs for women tennis players at the 2014 Italian Open, which is being played from May 12th to May 18, 2014, on the outdoor clay...The Examiner 2014-05-14
The following is a list of the prize money up for grabs for men tennis players at the 2014 Italian Open, which is being played from May 12th to May 18, 2014, on the outdoor...The Examiner 2014-05-14
The Independent
The Inquisitr
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Share PhotoReddit✉ Italy's Camila Giorgi serves the ball to Dominika Cibulkova of Slovakia at the Italian Open tennis tournament, in Rome, Tuesday, May 13, 2014. (AP Photo/Alessandra Tarantino) Italy's Camila Giorgi returns the ball to Dominika Cibulkova of Slovakia, at the Italian Open tennis tournament, in Rome, Tuesday, May 13, 2014. (AP Photo/Alessandra Tarantino)The...U~T San Diego 2014-05-13
Europe's 2014 Ryder Cup team will be announced after next year's Italian Open on Sunday, 31 August. Nine players qualify automatically - the first four coming from the European Points List, and the remaining five coming from the World Points List. Captain Paul McGinley will name his three wildcard picks the next day. "The Italian Open is steeped in history," he said. "And I...BBC News 2013-09-22
Share PhotoReddit✉ Bulgaria's Grigor Dimitrov reacts after winning a point against France's Edouard Roger-Vasselin at the Italian open tennis tournament in Rome, Monday, May 12, 2014. (AP Photo/Riccardo De Luca) Serbia's Ana Ivanovic celebrates after winning a point against Italy's Karin Knapp at the Italian open tennis tournament in Rome, Monday, May 12, 2014. Ivanovic won...U~T San Diego 2014-05-12
Starting this week Central Market is celebrating Italian culture with Passport Italy and it will continue through Tuesday May 13, 2014. This Passport event is a two week immersion in the cuisine, traditions, wine and culture of Italy. To launch the celebration there will be an opening ceremony on Saturday May 3 that will include Italian music, food and wine tastings. The ribbon...The Examiner 2014-05-02
Schiaparelli has officially returned to the runway courtesy of Christian Lacroix. In Paris today, Lacroix presented his much-anticipated haute couture collection for the Schiaparelli brand, which is currently undergoing a revival. Surrealist fashion designer Elsa Schiaparelli closed her fashion label in 1954 and died in 1973. But in 2006, Tod's CEO Diego Della Valle purchased...Huffington Post 2013-07-01
(Source: Narodna Skupstina Republike Srbije ) Thursday, 4 December 2014 European Integration Committee Delegation Takes Part in Conference of Parliamentary Committees for Union Affairs of EU Member States A delegation of the European Integration Committee, comprising Biljana Pantic Pilja and Dr Ivan Bauer, took part in the Conference of Parliamentary Committees for Union...noodls 2014-12-04
Share PhotoReddit✉ Germany's Tommy Haas returns the ball to Switzerland's Stanislas Wawrinka during their match at the Italian open tennis tournament in Rome, Thursday, May 15, 2014. (AP Photo/Gregorio Borgia) Switzerland's Stanislas Wawrinka serves the ball to Germany's Tommy Haas during their match at the Italian open tennis tournament in Rome, Thursday, May 15, 2014. (AP...U~T San Diego 2014-05-15
The Rome Masters (officially named as Internazionali BNL d'Italia) is an annual tennis tournament held in Rome, Italy. It is the most prestigious red clay tennis tournament in the world after the French Open, with the men's competition being an ATP World Tour Masters 1000 event on the Association of Tennis Professionals (ATP) tour, and the women's competition being a Premier 5 event on the Women's Tennis Association (WTA) tour. The two events were combined in 2011. The tournament is played on clay courts, currently during the second week of May. The event was previously known as the Rome Masters and adopted its present name in 2002. Rafael Nadal has won the title a record six times.
The Italian tennis championship was first held in 1930 in Milan, where it was played until 1934 before being moved to the Foro Italico in Rome in 1935. No event was held between 1936 and 1949. The competition resumed in 1950. It became "open" to professional players in 1969. Between 1970 and 1989 it was a premier tournament of the Grand Prix Tennis Tour and was part of the Grand Prix Championship Series top tier events. In 1990 it became an ATP Championship Series Single Week tournament.


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With rising concern nationally about Ebola haemorrhagic fever, the possibility of government-imposed quarantines looms as efforts are underway to contain a possible outbreak. But what are your rights under such conditions?
Scott Bomboy's posts.
Why Columbus Day isn't really a national holiday
This Monday, some folks will have a day off to commemorate Columbus Day and some won't. So what is the legal basis for the holiday and is it truly a national holiday?
Monaco's twin constitutional succession situation
Monaco is facing a rather interesting situation as two new heirs to the crown are on the way at the same time, and only one can rule under the principality's constitution.
Does Ted Cruz's proposed amendment protect some gay marriages?
How realistic is Senator Ted Cruz's proposed ban on the federal government or Supreme Court defining state marriage laws? It could be the longest of long shots, even though there is a constitutional provision for doing it.
Millard Fillmore: A President who faced a terrible personal conflict
As Constitution Daily concludes its Forgotten Presidents week, we look at the controversial figure of Millard Fillmore, whose decision to support pro-slavery legislation came with a great personal conflict.
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UCL recognises outstanding achievement during Eighth Annual Enterprise Awards
Winners of the eighth annual UCL Awards for Enterprise were announced on Wednesday 10th June, at a ceremony held at UCL Advances' new incubator space for product and creative businesses at King's Cross, BASE KX.
The awards recognise the efforts and accomplishments of UCL's most innovative and entrepreneurial staff, students, graduates and partner organisations in furthering enterprise and entrepreneurship at UCL
Find out more about UCL Awards for Enterprise 2015
Krista Macmillan
Database and Website Manager, UCL Enterprise
E: firstname.lastname@example.com
Krista Macmillan is the Enterprise Data & Systems Manager for UCL Enterprise Operations. Krista's responsibilities include managing a programme of online projects, development and management of systems to support UCL Enterprise industrial partnership and business engagement activities and representing UCL Enterprise at working groups and project boards to ensure it's strategic aims are represented in UCL-wide systems strategy
Krista joined UCL at the end of 2005 as Database Manager in the Business Development department of UCL Business before transferring to UCL Advances as Database & Website Manager in July 2006. In February 2012 Krista became part of UCL Enterprise Operations and took on the role of Enterprise Data & Systems Manager.
Before joining UCL, Krista worked as Database and Website Manager for Scottish Enterprise, the Economic Development Agency for Scotland. Previously, Krista worked at the University of California, Berkeley, as Information Systems Co-ordinator for the UCB Retirement Centre.
Krista has an MSc Information Systems and an MA (Hons) English Literature.


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Are you Rafael V C Guido?Claim your profile
Publications (33)75.86 Total impact
Article: Encapsulation of metalloporphyrins improves their capacity to block the viability of the human malaria parasite Plasmodium falciparum[Show abstract] [Hide abstract]
ABSTRACT: Several synthetic metallated protoporphyrins (M-PPIX) were tested for their ability to block the cell cycle of the lethal human malaria parasite Plasmodium falciparum. After encapsulating the porphyrin derivatives in micro- and nanocapsules of marine atelocollagen, their effects on cultures of red blood cells infected (RBC) with P. falciparum were verified. RBCs infected with synchronized P. falciparum incubated for 48 h with different concentrations of metalloporphyrin showed a toxic effect over a micromolar range. Strikingly, the IC50 of encapsulated metalloporphyrins reached nanomolar concentrations, where Zn-PPIX showed the best antimalarial effect, with an IC50 = 330 nM. This value is an 80-fold increase in the antimalarial activity compared to the antimalarial effect of non-encapsulated Zn-PPIX. These findings reveal that the incubation of P. falciparum infected-RBCs with 20 μM Zn-PPIX reduced the size of hemozoin crystal by 34%, whereas a 28% reduction was noticed with chloroquine, confirming the importance of heme detoxification pathway in drug therapy.Nanomedicine Nanotechnology Biology and Medicine 11/2014; 11(2). DOI:10.1016/j.nano.2014.09.018 · 5.98 Impact Factor
Article: 2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes[Show abstract] [Hide abstract]
ABSTRACT: The malaria parasite Plasmodium goes through two life stages in the human host, a non-symptomatic liver stage (LS) followed by a blood stage with all clinical manifestation of the disease. In this study, we investigated a series of 2-alkynoic fatty acids (2-AFAs) with chain lengths between 14 and 18 carbon atoms for dual in vitro activity against both life stages. 2-Octadecynoic acid (2-ODA) was identified as the best inhibitor of Plasmodium berghei parasites with ten times higher potency (IC50=0.34μg/ml) than the control drug. In target determination studies, the same compound inhibited three Plasmodium falciparum FAS-II (PfFAS-II) elongation enzymes PfFabI, PfFabZ, and PfFabG with the lowest IC50 values (0.28-0.80μg/ml, respectively). Molecular modeling studies provided insights into the molecular aspects underlying the inhibitory activity of this series of 2-AFAs and a likely explanation for the considerably different inhibition potentials. Blood stages of P. falciparum followed a similar trend where 2-ODA emerged as the most active compound, with 20 times less potency. The general toxicity and hepatotoxicity of 2-AFAs were evaluated by in vitro and in vivo methods in mammalian cell lines and zebrafish models, respectively. This study identifies 2-ODA as the most promising antiparasitic 2-AFA, particularly towards P. berghei parasites.Bioorganic & Medicinal Chemistry Letters 07/2014; 24(17). DOI:10.1016/j.bmcl.2014.07.050 · 2.33 Impact Factor
Article: Pattern recognition techniques applied to the study of leishmanial glyceraldehyde-3-phosphate dehydrogenase inhibition.[Show abstract] [Hide abstract]
ABSTRACT: Chemometric pattern recognition techniques were employed in order to obtain Structure-Activity Relationship (SAR) models relating the structures of a series of adenosine compounds to the affinity for glyceraldehyde 3-phosphate dehydrogenase of Leishmania mexicana (LmGAPDH). A training set of 49 compounds was used to build the models and the best ones were obtained with one geometrical and four electronic descriptors. Classification models were externally validated by predictions for a test set of 14 compounds not used in the model building process. Results of good quality were obtained, as verified by the correct classifications achieved. Moreover, the results are in good agreement with previous SAR studies on these molecules, to such an extent that we can suggest that these findings may help in further investigations on ligands of LmGAPDH capable of improving treatment of leishmaniasis.International Journal of Molecular Sciences 02/2014; 15(2):3186-203. DOI:10.3390/ijms15023186 · 2.34 Impact Factor
Article: Discovery of New Inhibitors of Mycobacterium tuberculosis InhA Enzyme Using Virtual Screening and a 3D-Pharmacophore-Based Approach[Show abstract] [Hide abstract]
ABSTRACT: Mycobacterium tuberculosis InhA (MtInhA) is an attractive enzyme to drug discovery efforts due to its validation as an effective biological target for tuberculosis therapy. In this work, two different virtual-ligand-screening approaches were applied in order to identify new InhA inhibitors' candidates from a library of ligands selected from the ZINC database. First, a 3-D pharmacophore model was built based on 36 available MtInhA crystal structures. By combining structure-based and ligand-based information, four pharmacophoric points were designed to select molecules able to satisfy the binding features of MtInhA substrate-binding cavity. The second approach consisted in using four well established docking programs, with different search algorithms, to compare the binding mode and score of the selected molecules from the aforementioned library. After detailed analyses of the results, six ligands were selected for in vitro analysis. Three of these molecules presented a satisfactory inhibitory activity with IC50 values ranging from 24 (± 2) μM to 83 (± 5) μM. The best compound presented an uncompetitive inhibition mode to NADH and 2-trans-dodecenoyl-CoA substrates, with Ki values of 24 (± 3) μM and 20 (± 2) μM, respectively. These molecules were not yet described as antituberculars or as InhA inhibitors, making its novelty interesting to start efforts on ligand optimization in order to identify new effective drugs against Tuberculosis having InhA as a target. More studies are underway to dissect the discovered uncompetitive inhibitor interactions with MtInhA.Journal of Chemical Information and Modeling 07/2013; 53(9). DOI:10.1021/ci400202t · 4.07 Impact Factor
Article: Synthetic chalcones and sulfonamides as new classes of Yersinia enterocolitica YopH tyrosine phosphatase inhibitors[Show abstract] [Hide abstract]
ABSTRACT: YopH plays a relevant role in three pathogenic species of Yersinia. Due to its importance in the prevention of the inflammatory response of the host, this enzyme has become a valid target for the identification and development of new inhibitors. In this work, an in-house library of 283 synthetic compounds was assayed against recombinant YopH from Yersinia enterocolitica. From these, four chalcone derivatives and one sulfonamide were identified for the first time as competitive inhibitors of YopH with binding affinity in the low micromolar range. Molecular modeling investigations indicated that the new inhibitors showed similar binding modes, establishing polar and hydrophobic contacts with key residues of the YopH binding site.European Journal of Medicinal Chemistry 04/2013; 64C:35-41. DOI:10.1016/j.ejmech.2013.04.018 · 3.43 Impact Factor
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ABSTRACT: In an article recently published in Química Nova, entitled "Chemistry Without Borders" ("Química Sem Fronteiras") [Pinto, A. C.; Zucco, C.; Galembeck, F.; Andrade, J. B.; Vieira, P. C. Quim. Nova 2012, 35, 2092], the authors highlighted the important aspects of science and technology with special emphasis on the field of Chemistry and its contributions toward a more prosperous Brazil of future. As a second step in that direction, this article extends the discussion of a key issue for the country in the framework of the chemistry community through the so called position papers in strategic areas. This document is a part of the contribution of the Brazilian Chemical Society to the World Science Forum to be held in Rio de Janeiro in November 2013. In this context, the present paper provides a brief discussion on neglected tropical diseases (NTDs) with emphasis on the current challenges and opportunities towards the development and evolution of the field. NTDs leads to illness, long-term disability or death, and has severe social, economic and psychological consequences for millions of men, women, and children worldwide. In most cases, the available treatments are inadequate and extremely limited in terms of efficacy and safety, leading to an urgent demand for new drugs. In addition to the traditional challenges involved in any drug discovery process, it is widely recognized that there is an innovation gap and a lack of investment for research and development (R&D) in the area of NTDs. In the last few decades, methods toward combating, eradication, prevention, and treatment of NTDs have been repeatedly emphasized in the major international agendas. Developments in these strategies and alliances have continued to have an essential impact, particularly in the area of drug discovery, both in Brazil and globally and should be encouraged and supported. Several examples of international activities dedicated to the reduction of the devastating global impact of NTDs can be provided. Despite the beneficial developments in the past 30 years, NTDs continue to devastate poor communities in remote and vulnerable areas, in large part, due to market failures and public policies. Recent studies have shown that among 756 new drugs approved between 2000 and 2011, only four new chemical entities (NCEs) were identified for the treatment of malaria, while none were developed against NTDs or tuberculosis. Furthermore, only 1.4% of approximately 150,000 clinical trials were registered for neglected diseases, with a smaller number of trials for NCEs. Establishment and strengthening of global strategies involving the triad "governmentacademiaindustry" is fundamental to the success in R&D of new drugs for NTDs. National and international publicprivate initiatives that aim to create, encourage, and invest in R&D projects have been implemented and therefore are of utmost importance to successfully integrate Brazil into this new paradigm. It is essential to lay the foundation for mechanisms that will intensify investments in infrastructure, training, and qualification of personnel with an ultimate strategic vision that foresees continuity. Our research group has made significant contributions to the development of this field with the goal of forging new frontiers while tackling both current and future challenges that include indispensable elements such as innovation and integration.Química Nova 12/2012; 36(10):1552-1556. DOI:10.1590/S0100-40422013001000011 · 0.66 Impact Factor
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ABSTRACT: Thiosemicarbazones are cruzain inhibitors which have been identified as potential antitrypanosomal agents. In this work, several molecular properties were calculated at the density functional theory (DFT)/B3LYP/6-311G* level for a set of 44 thiosemicarbazones. Unsupervised and supervised pattern recognition techniques (hierarchical cluster analysis, principal component analysis, kth-nearest neighbors, and soft independent modeling by class analogy) were used to obtain structure–activity relationship models, which are able to classify unknown compounds according to their activities. The chemometric analyses performed here revealed that 12 descriptors can be considered responsible for the discrimination between high and low activity compounds. Classification models were validated with an external test set, showing that predictive classifications were achieved with the selected variable set. The results obtained here are in good agreement with previous findings from the literature, suggesting that our models can be useful on further investigations on the molecular determinants for the antichagasic activity. © 2012 Wiley Periodicals, Inc.International Journal of Quantum Chemistry 10/2012; 112(20). DOI:10.1002/qua.24213 · 1.17 Impact Factor
Article: Molecular Features for Antitrypanosomal Activity of Thiosemicarbazones Revealed by OPS-PLS QSAR Studies.[Show abstract] [Hide abstract]
ABSTRACT: A quantitative structure-activity relationship analysis was employed to explore the relationship between the molecular structure of thiosemicarbazone analogues and the inhibition of the cysteine protease cruzain, a validated target for Chagas' disease treatment. A data set containing 53 thiosemicarbazone derivatives was used to produce a quantitative model for activity prediction of unknown compounds. Several electronic descriptors were obtained through DFT calculations, along with a large amount of Dragon descriptors. The ordered predictor selection (OPS) algorithm was employed to select the most relevant descriptors to perform PLS regressions. With this procedure, significant correlation coefficients (r 2 = 0.85, q 2 = 0.78) were achieved. Furthermore, predicted values for an external test set are in good agreement with the experimental results, indicating the potential of the model for untested compounds. Additional validation tests were carried out, indicating that a robust and reliable model was obtained to be used in the design of new thiosemicarbazones with improved cruzain inhibition potential.Medicinal chemistry (Shāriqah (United Arab Emirates)) 07/2012; 8(6):1045-56. DOI:10.2174/157340612804075043 · 1.39 Impact Factor
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ABSTRACT: Drug discovery has moved toward more rational strategies based on our increasing understanding of the fundamental principles of protein-ligand interactions. Structure( SBDD) and ligand-based drug design (LBDD) approaches bring together the most powerful concepts in modern chemistry and biology, linking medicinal chemistry with structural biology. The definition and assessment of both chemical and biological space have revitalized the importance of exploring the intrinsic complementary nature of experimental and computational methods in drug design. Major challenges in this field include the identification of promising hits and the development of high-quality leads for further development into clinical candidates. It becomes particularly important in the case of neglected tropical diseases (NTDs) that affect disproportionately poor people living in rural and remote regions worldwide, and for which there is an insufficient number of new chemical entities being evaluated owing to the lack of innovation and R&D investment by the pharmaceutical industry. This perspective paper outlines the utility and applications of SBDD and LBDD approaches for the identification and design of new small-molecule agents for NTDs.Pure and Applied Chemistry 01/2012; 84(9). DOI:10.1351/PAC-CON-11-11-07 · 3.11 Impact Factor
Article: Synthesis, Biological Evaluation, And Molecular Modeling of Chalcone Derivatives As Potent Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatases (PtpA and PtpB)[Show abstract] [Hide abstract]
ABSTRACT: Tuberculosis (TB) is a major infectious disease caused by Mycobacterium tuberculosis (Mtb). According to the World Health Organization (WHO), about 1.8 million people die from TB and 10 million new cases are recorded each year. Recently, a new series of naphthylchalcones has been identified as inhibitors of Mtb protein tyrosine phosphatases (PTPs). In this work, 100 chalcones were designed, synthesized, and investigated for their inhibitory properties against MtbPtps. Structure–activity relationships (SAR) were developed, leading to the discovery of new potent inhibitors with IC50 values in the low-micromolar range. Kinetic studies revealed competitive inhibition and high selectivity toward the Mtb enzymes. Molecular modeling investigations were carried out with the aim of revealing the most relevant structural requirements underlying the binding affinity and selectivity of this series of inhibitors as potential anti-TB drugs.Journal of Medicinal Chemistry 12/2011; 55(1). DOI:10.1021/jm2012062 · 5.48 Impact Factor
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ABSTRACT: The identification of promising hits and the generation of high quality leads are crucial steps in the early stages of drug discovery projects. The definition and assessment of both chemical and biological space have revitalized the screening process model and emphasized the importance of exploring the intrinsic complementary nature of classical and modern methods in drug research. In this context, the widespread use of combinatorial chemistry and sophisticated screening methods for the discovery of lead compounds has created a large demand for small organic molecules that act on specific drug targets. Modern drug discovery involves the employment of a wide variety of technologies and expertise in multidisciplinary research teams. The synergistic effects between experimental and computational approaches on the selection and optimization of bioactive compounds emphasize the importance of the integration of advanced technologies in drug discovery programs. These technologies (VS, HTS, SBDD, LBDD, QSAR, and so on) are complementary in the sense that they have mutual goals, thereby the combination of both empirical and in silico efforts is feasible at many different levels of lead optimization and new chemical entity (NCE) discovery. This paper provides a brief perspective on the evolution and use of key drug design technologies, highlighting opportunities and challenges.Combinatorial chemistry & high throughput screening 08/2011; 14(10):830-9. DOI:10.2174/138620711797537067 · 1.93 Impact Factor
- Acta Crystallographica Section A Foundations of Crystallography 08/2011; 67(a1):C51-C52. DOI:10.1107/S0108767311098801 · 2.07 Impact Factor
Article: Sulfonyl-hydrazones of cyclic imides derivatives as potent inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase B (PtpB)[Show abstract] [Hide abstract]
ABSTRACT: Searching lead compounds for new antituberculosis drugs, the activity of synthetic sulfonamides and sulfonyl-hydrazones were assayed for their potential inhibitory activity towards a protein tyrosine phosphatase from Mycobacterium tuberculosis – PtpB. Four sulfonyl-hydrazones N-phenylmaleimide derivatives were active (compounds 14, 15, 19 and 21), and the inhibition of PtpB was found to be competitive with respect to the substrate p-nitrophenyl phosphate. Structure-based molecular docking simulations were performed and indicated that the new inhibitor candidates showed similar binding modes, filling the hydrophobic pocket of the protein by the establishment of van der Waals contacts, thereby contributing significantly to the complex stability.Medicinal Chemistry Communication 06/2011; 2(6):500-504. DOI:10.1039/C0MD00253D · 2.63 Impact Factor
Article: Quantitative structure-activity studies on a series of migrastatin analogs as inhibitors of cancer cell metastasis.[Show abstract] [Hide abstract]
ABSTRACT: Migrastatin, a macrolide natural product, and its structurally related analogs are potent inhibitors of cancer cell metastasis, invasion and migration. In the present work, a specialized fragment-based method was employed to develop QSAR models for a series of migrastatin and isomigrastatin analogs. Significant correlation coefficients were obtained (best model, q2 = 0.76 and r2 = 0.91) indicating that the QSAR models possess high internal consistency. The best model was then used to predict the potency of an external test set, and the predicted values were in good agreement with the experimental results (R2 pred = 0.85). The final model and the corresponding contribution maps, combined with molecular modeling studies, provided important insights into the key structural features for the anticancer activity of this family of synthetic compounds based on natural products.Medicinal chemistry (Shāriqah (United Arab Emirates)) 05/2011; 7(3):155-64. DOI:10.2174/157340611795564240 · 1.39 Impact Factor
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ABSTRACT: Cathepsin V is a lysosomal cysteine peptidase highly expressed in thymus, testis and corneal epithelium. Eleven acridone alkaloids were isolated from Swinglea glutinosa (Bl.) Merr. (Rutaceae), with eight of them being identified as potent and reversible inhibitors of cathepsin V (IC(50) values ranging from 1.2 to 3.9 μM). Detailed mechanistic characterization of the effects of these compounds on the cathepsin V-catalyzed reaction showed clear competitive inhibition with respect to substrate, with dissociation constants (K(i)) in the low micromolar range (2, K(i)=1.2 μM; 6, K(i)=1.0 μM; 7, K(i)=0.2 μM; and 11, K(i)=1.7 μM). Molecular modeling studies provided important insight into the structural basis for binding affinity and enzyme inhibition. Experimental and computational approaches, including biological evaluation, mode of action assessment and modeling studies were successfully employed in the discovery of a small series of acridone alkaloid derivatives as competitive inhibitors of catV. The most potent inhibitor (7) has a K(i) value of 200 nM.Bioorganic & medicinal chemistry 02/2011; 19(4):1477-81. DOI:10.1016/j.bmc.2010.12.056 · 2.95 Impact Factor
Article: Discovery of New Inhibitors of Schistosoma mansoni PNP by Pharmacophore-Based Virtual Screening[Show abstract] [Hide abstract]
ABSTRACT: Schistosomiasis is considered the second most important tropical parasitic disease, with severe socioeconomic consequences for millions of people worldwide. Schistosoma mansoni , one of the causative agents of human schistosomiasis, is unable to synthesize purine nucleotides de novo, which makes the enzymes of the purine salvage pathway important targets for antischistosomal drug development. In the present work, we describe the development of a pharmacophore model for ligands of S. mansoni purine nucleoside phosphorylase (SmPNP) as well as a pharmacophore-based virtual screening approach, which resulted in the identification of three thioxothiazolidinones (1-3) with substantial in vitro inhibitory activity against SmPNP. Synthesis, biochemical evaluation, and structure-activity relationship investigations led to the successful development of a small set of thioxothiazolidinone derivatives harboring a novel chemical scaffold as new competitive inhibitors of SmPNP at the low-micromolar range. Seven compounds were identified with IC(50) values below 100 μM. The most potent inhibitors 7, 10, and 17 with IC(50) of 2, 18, and 38 μM, respectively, could represent new potential lead compounds for further development of the therapy of schistosomiasis.Journal of Chemical Information and Modeling 09/2010; 50(9):1693-705. DOI:10.1021/ci100128k · 4.07 Impact Factor
- Burger's Medicinal Chemistry, Drug Discovery and Development, 09/2010; , ISBN: 9780471266945
Article: Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: Kinetics, molecular modeling, toxicity and effect on growth[Show abstract] [Hide abstract]
ABSTRACT: Tuberculosis (TB) is a major cause of morbidity and mortality throughout the world, and it is estimated that one-third of the world's population is infected with Mycobacterium tuberculosis. Among a series of tested compounds, we have recently identified five synthetic chalcones which inhibit the activity of M. tuberculosis protein tyrosine phosphatase A (PtpA), an enzyme associated with M. tuberculosis infectivity. Kinetic studies demonstrated that these compounds are reversible competitive inhibitors. In this work we also carried out the analysis of the molecular recognition of these inhibitors on their macromolecular target, PtpA, through molecular modeling. We observed that the predominant determinants responsible for the inhibitory activity of the chalcones are the positions of the two methoxyl groups at the A-ring, that establish hydrogen bonds with the amino acid residues Arg17, His49, and Thr12 in the active site of PtpA, and the substitution of the phenyl ring for a 2-naphthyl group as B-ring, that undergoes pi stacking hydrophobic interaction with the Trp48 residue from PtpA. Interestingly, reduction of mycobacterial survival in human macrophages upon inhibitor treatment suggests their potential use as novel therapeutics. The biological activity, synthetic versatility, and low cost are clear advantages of this new class of potential tuberculostatic agents.Bioorganic & medicinal chemistry 06/2010; 18(11):3783-9. DOI:10.1016/j.bmc.2010.04.051 · 2.95 Impact Factor
Article: Structural Insights into the Molecular Basis Responsible for the Effects of Immobilization on the Kinetic Parameters of Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi and Human[Show abstract] [Hide abstract]
ABSTRACT: The development of fast and reliable methods for the identification of new bioactive compounds is of utmost importance to boost the process of drug discovery and development. Immobilized enzyme reactors (IMERs), integrated with high performance liquid chromatography (HPLC), are attractive and versatile tools for screening collections consisting of natural products and synthetic small molecules. Standard kinetic parameters of the immobilized enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from both Trypanosoma cruzi de and human have been determined (T. cruzi: K-M(G3P) = 0.50 mmol L-1; K-M(NAD+) = 0.67 mmol L-1; humana: K-M(G3P) = 3.7 mmol L-1; K-M(NAD+) = 0.75 mmol L-1), and comparisons of these values with those of the parasite and human free enzymes indicate a decrease in the affinity for the immobilized system (T. cruzi: K-M(G3P) = 0.42 mmol L-1; K-M(NAD+) = 0.26 mmol L-1; humana: K-M(G3P) = 0.16 mmol L-1; K-M(NAD+) = 0.18 mmol L-1). Interestingly, despite the kinetic differences between the two systems, the immobilized GAPDHs retained the required structural requirements for molecular recognition and biological activity, increasing the stability the enzyme. In the present work, we described an integrated structural analysis which has provided important insights into the molecular basis underlying the effects of immobilization on the ligand-receptor interactions and consequent enzymatic activity and kinetics parameters.Journal of the Brazilian Chemical Society 01/2010; 21(10-10):1845-1853. DOI:10.1590/S0103-50532010001000008 · 1.25 Impact Factor
Article: Planejamento de fármacos, biotecnologia e química medicinal: aplicações em doenças infecciosasEstudos Avançados 12/2009; 24(70):81-98. DOI:10.1590/S0103-40142010000300006
Top Journals
University of São Paulo
San Paulo, São Paulo, Brazil
- Institute of Physics São Carlos (IFSC)


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Halestorm Plan 'To Hale and Back' Photo Book for May 2015 Release
Halestorm will follow the 'Into the Wild Life' album with the 'To Hale and Back' photo book in May.
Halestorm will follow the 'Into the Wild Life' album with the 'To Hale and Back' photo book in May.
Rob Zombie recently wrapped his first day of shooting on his new horror film 31. The writer and director celebrated the beginning of the shoot by announcing that acclaimed actor Malcolm McDowell is portraying Father Murder.
Join Tony LaBrie at LaFontaine Used Car King to win tickets to see Halestorm at The Whiting!
Rob Zombie has cast actors best known for their roles in 'Welcome Back, Kotter' and 'Pee-Wee's Big Adventure' in his new film '31.'
Halestorm fight the 9 to 5 grind by enjoying an "amen" moment rocking out in their 'Amen' video.
Rob Zombie has announced via an Instagram post that he has cast Torsten Voges as the Death-Head in his upcoming horror film 31.
Watch Rob Zombie's 'Ging Gang Gong' live video and get a peek at the location scouting for his '31' film.
Halestorm's Lzzy Hale chats with 'Loudwire Nights' host Full Metal Jackie about their 'Into the Wild Life' disc, their upcoming tour and more.
After announcing Linkin Park as one of the headliners of the 2015 Loudwire Music Festival, we're proud to unveil a new wave of bands who have joined the bill.
Halestorm offer up an incendiary performance for their 'Apocalyptic' video.
The Whiting Auditorium in Flint will come alive as these two bands take the stage on Tuesday, May 19th! Banana 101.5 presents Halestorm and The Pretty Reckless at the Whiting!
Slipknot / Stone Sour frontman Corey Taylor points out some of the problems with the Grammy voting for the metal category.


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The Top 10 In Action Sports
01Brick By Brick: Camping Lego Style
02Booze and Bikes: 14 Tours That Let Combine Two of the Best Things in the World
03Who Needs Hollywood? These Incredible Videos Were All Filmed on the Simplest Cameras
04Sam Pilgrim vs. The World: The Champion Aiming To Reclaim His Crown In A New Era Of Biking
05Eccentric Adventures Episode 2: Britain's Most Brutal Illegal Event is All About Cheese
06A Journey Into Darkness: We Went Mountain Biking in the Abandoned Mines of Slovenia
07After the Apocalypse: Inside The World's Most Breathtaking Ghost Towns
08Debate: Let's Stop Hating On Parents Who Want To Raise Adventurous Kids
09Guns, Roses, And Eating Insects: Adventure Cycling in Vietnam
10From Intense Trails to Intensive Care: Dicing with Death In a Mountain Biking Paradise
52 weeks of film #5 The Johnpound
A Mountain Biking video by tomgrundy - 3,178 views
With two minibike tracks and set of winter trails - The Johnpound is one of the funnest places in the world. A day of diggings completes the line (for now) which is obviously followed by riding. Featuring: Olly Wilkins Sam Reynolds Brendan Fairclough Party John Seb Yate Dave Valler Music: 'The Promise' - Breakage www.TomGrundy.co.uk
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Digital Tool Tuesday: Useful web sites
Digital Tool Tuesday: Useful (and offbeat) websites for features reporting
In this edition, some resourceful websites to use in lifestyle reporting, courtesy of The Journalist's Toolbox, itself a great compilation of what journalists need to navigate reporting in the digital age.
Food Timeline
Simply done, this is a timeline of the history of food. Want to know when "The Virginia Housewife" was first published? This timeline has that. Want to find out when the first dedicated baby food was produced; it's got that, too. Click on the hyperlink and get a lot of well sourced material to mine for any food history story. Bonus: a page that outlines food prices in the past.
A USDA site, this includes great consumer information and personal tools for weight loss and increasing activity. Editors will find the Food-A-Pedia a useful tool to discover nutritional information on any food.
Math for journalists
Math tutorials from the L.A. Times Robert Niles. We like the simple explanation of percent change.
Digital Tool Tuesday
Digital Tool Tuesday Welcome to a new weekly feature of SFJ, in which we share tips about a digital tool to leverage for lifestyle and arts and entertainment coverage. The tool: Storymap
What does it do? Creates clickable map that allows you to tell a story at each point.
What's cool about it? Embed video and photos at each point, bringing a map to life.
Deadline extended for 2014 Penny Bender Fuchs Diversity Fellowship
SFJ's Penny Bender Fuchs Diversity Fellowship Program is seeking applications from journalists of color who are interested in attending our annual conference, happening Aug. 20-23 at the Freedom Forum in Nashville. Programming will have heavy emphasis on multimedia, leadership and writing.
Diversity fellows learn what's happening in features departments nationwide while networking with outstanding journalists specializing in lifestyle coverage. Fellowships cover SFJ conference registration, airfare and hotel. Fellows will also receive a $300 stipend to be used toward conference-related expenses such as baggage and transportation fees and meals not covered by the conference.
Fellows are asked to contribute to the conference by completing a project and presenting a short report to the group at the conclusion of the event.
@WeAreSfj Among "151 Twitters Worth a Follow" in #journalism
Do you recognize some of these Twitter handles: @nytimes, @poynter, @stkonrath and @wikileaks?
According to JournalismDegree.org, they are among the "151 Twitters Worth A Follow" in its recently released "Best in #Journalism" list.
So the Society for Feature Journalism — @WeAreSFJ — is in good company at spot #106!
Here's JournalismDegree's description of our Twitter account: "The Society of Features Journalism helps journalists refine their craft through some of the most innovative posts across the internet. They're incredibly active in retweeting other notable journalism publications, which only makes their feed stronger."
JournalismDegree.org describes itself as "a site dedicated to providing timely and relevant information about journalism degrees and programs."
It decided to put out this list because of Twitter's effect on journalism.
"These are some of the journalists, bloggers, and news organizations that are pushing the limits of what can be accomplished with Twitter," the site explains. "Budding journalists and seasoned pros should be following every one of these accounts."
Thank you! We are honored to have been included on this list and we'll keep tweeting away.
Dallas Morning News' writing contest celebrates narrative nonfiction by newspapers
The Dallas Morning-News is sponsoring a new contest honoring narrative nonfiction writing in a daily U.S. newspaper or a U.S. newspaper website. It's called the Best American Newspaper Narrative Writing Contest. The contest is conducted by the Mayborn Conference.
The prizes are impressive:
- First place winner will receive $5,000 and free registration to attend the Mayborn Literary Nonfiction Conference July 19-21, 2013 in Grapevine, Texas
- Second place winner will receive $2,000
- Third place winner will receive $1,000
Submissions must have been published between Jan. 1, 2012 and December 31, 2012. Deadline to enter is June 1.
Donate to SFJ Foundation today!
The SFJ Foundation is accepting donations to seed the start of its new life.
As an incentive, board president Tom Huang (of Poynter and Dallas Morning News fame) has generously offered to match donations received through Dec. 31, up to $1,000.
Perhaps this could be one of your #26actsofkindness, or your way to ensure the future of features journalism. Through our annual conference and the Penny Bender Fuchs Diversity Fellows Program, SFJ aims to advance and recognize the important role features journalism plays in the media and society. What would we be without our stories?
To make a contribution, send a check payable to SFJ Foundation and mail to SFJ Foundation, 1100 Knight Hall, University of Maryland, College Park, MD 20742.
No donation is too small.


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Britannica Online Academic Edition and Image Quest Combined Agreement - 2013 to 2015
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The Encyclopaedia Britannica Academic Edition online offers a unique educational experience – rigorously curated, peer-enhanced learning. Research confidently with Britannica Online Academic Edition with expert information and a host of research tools designed to support advanced study. Delivering clear, current and correct material (articles, images, videos, eBooks and journal articles) – all clearly cited and referenced, providing research for undergraduates, graduates and faculty. Encyclopædia Britannica has recently launched Britannica Image Quest, an online image library which contains images from the world's best image providers including National Geographic, Getty Images, National History Museum and many more. This easy-to-use online portal provides quick access to rights-cleared high-quality images. The combined agreement offers subscribers a 5% discount.
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British History Online Premium Content 2013 - 2018
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British History Online is a non-profit digital library of the core printed primary and secondary sources of British history from 1100 to the mid-twentieth century, with a focus on the medieval and early modern period. The free content consists of approximately 950 volumes. The Premium Content allows access to an additional 184 volumes, which include: the Calendar of State Papers; Domestic and the Calendars of State Papers for Scotland and Ireland; the Calendars of Border Papers; the Calendars of Home Office Papers of George III; the Parliament Rolls of Medieval England; the National Archives Calendar of Close Rolls; the Calendars of the Committee for the Advancement of Money; and the Calendars of the Committee for Compounding. The online calendar texts are fully searchable, and access to their original page scans is also available for subscribers. The premium content can be searched and browsed seamlessly alongside the free content.
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BSOL is a teaching, research and study tool for a broad range of courses and disciplines. By embedding standards into course curricula, students are prepared for the demands of the commercial world by helping them make the transition into employment. BSOL is used by professionals around the world and it is a comprehensive source of draft, current and withdrawn British standards as well as adopted European and international standards. BSOL includes a full range of technical and business content and covers a broad range of disciplines for all industry sectors. Updated daily, this growing resource currently contains the full text (PDFs) of more than 60,000 standards and books accessible 24/7 directly from a desktop.
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Cambridge Books Online Evidence-based Acquisition 2014
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Cambridge Books Online is the main eBook platform of Cambridge University Press, offering straightforward user-friendly access to over 24,000 titles. Titles are available in almost every major academic and professional subject, with both backlist and frontlist well represented.
Cambridge Books Online Evidence-based Acquisition 2015
Cambridge University Press
Cambridge Books Online is the main eBook platform of Cambridge University Press, offering straightforward user-friendly access to over 27,000 titles with a list value of over £2.5 million. Titles are available in almost every major academic and professional subject, with both backlist and frontlist well represented.
Cambridge University Press Journals 2015
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Cambridge University Press is the printing and publishing house of the University of Cambridge. The Press is the oldest publishing house in the world, recently celebrating 425 years of continuous publishing. CUP is a not-for-profit publisher and its mission is to advance learning, knowledge and research worldwide. CUP currently publishes 341 journals and over 2,500 books annually. Key areas covered by CUP journals are mathematics, physical sciences, environment and conservation, agriculture, neuroscience and biomedicine, history, area studies, language and linguistics, and political science and international relations.


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Today I reveal an app, which shall not be named, whose purpose is to sync files from disparate Android devices and Personal Computers. What? You say you are editing an Excel document on your Android device for a board meeting you are running late for? You say that was on a Samsung Galaxy S III but now all you posess is your Droid RAZR MAXX. MADNESS! We may or may not be of help to you!
• Heavily Inspired by Dropbox's iPhone app and mobile web design
• Icons inspired from the old Google Docs icons. I'm looking for the guy who did those. I'll post it here when I find him.
keyboard shortcuts: ← previous shot → next shot L or F like Z toggle zoom


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Spotlight on Mom: Lisa Taylor
Lisa Taylor's toys of choice were never the usual. Instead of dolls, she gravitated to microscopes and chemistry kits. She decided early on to pursue a career in chemistry and earned a bachelor's degree in medical technology. She started out working at the blood bank at the Regional Medical Center at Memphis, and then switched to Lifeblood, where she has worked for 20 years. She recently became vice president of laboratory operations for Lifeblood. "There is a satisfaction in knowing that the products we provide make a difference in someone's life," she says.
Much like with her career, Lisa also decided early on the man of her life. Her parents' neighbor's son came to Millington from Indiana every year to spend the summer with his dad -- and later on, with Taylor. But once Taylor went to college, she and Ron, a firefighter, lost touch. They reconnected years later, married and had two children. The couple, parents of Hannah, 9, Jake, 8, Lisa's stepdaughter, Lacey, and grandparents of Kloe, 2, live two doors down from Lisa's mother and Ron's father in Millington. Two Italian greyhounds and a Chihuahua complete their lives. The couple hope to take their children to Walt Disney World soon. Lisa recently answered questions from Midsouthmoms.com:
What's one thing that always makes your day? Bedtime with the kids and getting a recap on their day. We always spend a few minutes giggling and catching up. It's the time of the day that makes me feel like I haven't missed out because I was at work.
If you were to give special praise to someone right now, who would it be? My mom. She is my rock. She is always there helping me with the kids, encouraging me professionally or just giving me the little push or hug that I need to keep moving forward.
What's the best thing about living in the Mid-South? The people are awesome. Most people in the Mid-South seem to stay in the Mid-South, so your lifelong friends are never far away, even if you lose touch for a little while.
What do you do when you feel overwhelmed? Relax on my porch swing with a good book and a cup of coffee.
Have you had a worst "working-mom" moment? One of my children has asthma. The worst moments are when the school calls and says she's having an asthma attack. The instant collision of juggling the guilt, the panic and the work priorities makes your heart sink.
What's your favorite pastime? Playing outside with the kids. I love it when time changes and I have more afternoon hours. We ride the four-wheeler, go swimming, fishing or play basketball.
What is something people would be surprised to learn about you? I love to absorb all the Memphis history that is found in Elmwood Cemetery. There is something reassuring about climbing over the bridge into the silence and peace.
Favorite movie: "Legends of the Fall" and "The Wizard of Oz"
Favorite TV show: "I Love Lucy"
Favorite timesaving tip: Throw away junk mail before you bring it in the house.
Subscribe to The Commercial Appeal
Need Help? Call us at 1-888-789-0831.
Monday-Friday: 6am-5pm / Saturday: 6:30am-11:30am / Sunday: 6am-1pm


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Jesus is in My Heart Button
Design ID: 11861985
http://upfrontgear.spreadshirt.com/ Upfront Gear is a clothing site where you can find Christian clothing and gear and other clean subjects that describes who you are. Let your clothes speak for you.
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These fashionable 1" buttons are a great way to decorate any article of clothing. Throw them on a jacket, tote bag or even your shoe laces to add a little bit of flash to an otherwise normal piece of gear.
still to fill


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Posted by Adam Jacobi
USC fans wondering why former assistant Willie Mack Garza resigned so abruptly two days before the start of this season now have an answer -- and that answer has a paper trail. According to a report by Yahoo Sports, Willie Lyles informed NCAA investigators that Garza had wired him $1,500 in 2009 to get coveted tailback Lache Seastrunk onto the Tennessee campus for an unofficial visit; Garza had been an assistant of Lane Kiffin at UT at that point, before Kiffin brought Garza with him to USC's staff in 2010.
On unofficial visits, recruits and their families are responsible for all costs incurred, so if Garza supplied that money to Lyles for the purposes of getting Seastrunk to campus, that's a serious violation of NCAA rules. Whether Garza gave money to Lyles is not in question, though; Yahoo Sports has a copy of the Moneygram record of that transaction, and sure enough, there's $1,500 going from Garza to Lyles. Being that Lyles himself told the NCAA that the money was to pay for Seastrunk's plane tickets, which totaled $1,446.80 in a purchase two weeks prior to the Moneygram transaction, there doesn't appear to be much wiggle room for Garza.
CBSSports.com first reported that Garza's departure from USC was related to an NCAA probe of Tennessee's recruiting practices on the day that Garza resigned, on September 1. That report has now been proven accurate by this Yahoo story.
For Garza's efforts above and beyond the NCAA guidelines, Tennessee didn't get much; not only did Seastrunk not commit to the Volunteers, of course, he didn't even take an official visit to Knoxville once it was time to make those choices. Seastrunk famously chose Oregon over Auburn in a recruiting process that still leaves a sour taste in Tigers fans' mouths to this day, and once the reports surfaced of Lyles maintaining close relationship with recruits even while getting paid large sums of money by the schools recruiting them, Seastrunk ended up transferring to Baylor.
For as bad as this report makes Garza look in the eyes of the NCAA, however, the real entity in danger here is Tennessee; that athletic department was hit with a failure to monitor charge in August among various major infractions perpetrated by then-head basketball coach Bruce Pearl, and the program is nowhere near completing its two years of probation handed down by the NCAA. If the NCAA finds this to be another egregious flouting of recruiting regulations, Tennessee is liable to be considered a "repeat offender" by the Committee on Infractions, and that easily could mean serious, long-lasting consequences for the entire athletic department.
Blog Entry
Report: Former Vols assistant wired cash to Lyles
Posted on: September 27, 2011 2:16 am
Category: NCAAF
Since: Jun 29, 2011
Posted on: September 28, 2011 9:32 am
Report: Former Vols assistant wired cash to Lyles
I agree, Lane is the one who hired him. Also Lane has the top dog, so with being the head guy in charge, it's reflected on him what his assist. coaches does. I also agree with being excitied the new blood was brought in, after Phil Fulmer left. Change was needed at that time and Lane and his father had NFL experince. But as you guys know things didn't workout as well as we all wanted, so in comes Derek Dooley. Dooley is doing a great job, and I do believe he will guide the Vols back to where this team needs and wants to be. But it will take time.....GO Vols!
Since: Aug 29, 2006
Posted on: September 28, 2011 8:31 am
Report: Former Vols assistant wired cash to Lyles
And it is clear you can relate to education being secondary from looking at your hideous spelling and grammar. When you get off the clock at Mickey D's, try going back for your GED.
The athlete is guilty, of course. But anyone around Lame Kitten is clearly as dirty as he is, a fact proven once again. If holier-than-thou Pat Haden doesn't can that loser, then he is also a hypocrite. (Sorry to use such a big word, orangeloser... maybe you'll see that when you get back to middle school.) Except he won't do it, because the University of Spoiled Children has a history of playing by their own rules, all the way back to giving a scholarship in the late 60's to a guy who could not read or write. He was a great slasher thought.... right Orenthal?
Trojans burst under pressure!
Since: Feb 24, 2007
Posted on: September 28, 2011 7:35 am
Report: Former Vols assistant wired cash to Lyles
I have NEVER been a member of "Team SEC" for just this reason, dead oaks, $180,000 Heisman Trophy winners, Alabama RBs with $50,000 SUVs, et al.
Since: Jun 12, 2009
Posted on: September 28, 2011 6:39 am
Report: Former Vols assistant wired cash to Lyles
Why is it wherever Lane Kiffin goes, bad news follows him? I have enormous repsect for his father Monte, but even he has been tarnished with the same brush by working with his own son. That must be embarrasing. I love the Vols, and alll their history, but this is a dark patch, and in retrospect, USC did them a favour taking Kiffin off their hands. It would seem Coach Kiffin isn't deterred from his unscrupulous ways with minor personal or even heavy team sanctions. Maybe a suspension is needed to get this guy to understand that CHEATING IS NOT ALLOWED. There is a fine line between aggressive and illegal recruiting, and it seems to me this guy doesn't know or doesn't care where that line is...
Since: Oct 13, 2007
Posted on: September 28, 2011 12:48 am
Report: Former Vols assistant wired cash to Lyles
It seems like some UT fans have selective memory when it comes to Lane Kiffin. It was your AD that hired the guy, and most UT fans were thrilled with the hire.Yeah...that's kinda how that works, we all know who hired him and yes most of us inlcuding me, were excited about it. He was a young and fired up head coach. That in itself was a big change from what Vols fans had been used to, no offense Coach Fulmer. BUT no one was expecting him and his entire d-bag staff to committ the infractions they did or to bounce to USC so quickly. During which time they were trying to steal the recruits they had brought to Tennessee and push them towards USC. Lame Kiffin should pay for his actions, not the school that was left in the wake of the disaster also known as his coaching career. Monte Kiffin and Ed Orgeron should get their fair share of punishment. The NCAA has already used a Tennessee coach as their example, time to follow through and use it on the next set of clowns. Go Vols!
Since: Jan 4, 2009
Posted on: September 27, 2011 11:25 pm
Report: Former Vols assistant wired cash to Lyles
Coach Lane had nothing to do with this!!! Absolutely nothing!! Why are you guys always picking on him?
The money was to get some tatoos....what's wrong with that?? You want him to fit in on campus. Or maybe it was to get some food....You know those kids get hungry on those trips. You wouldn't want him to come onto campus and not be coherent.
Coach Lane had nothing to do with this!!! Absolutely nothing!!
Since: Apr 10, 2011
Posted on: September 27, 2011 9:54 pm
Report: Former Vols assistant wired cash to Lyles
I agree, what a loser!
Since: Jun 29, 2011
Posted on: September 27, 2011 9:36 pm
Report: Former Vols assistant wired cash to Lyles
IMO why I think Willie Lyles, is putting all this info out because he wants to stay in the public eye (media attention). When he was doing his dirt he didn't care to blow the whistle, so why now. This guy is trying to stay relevant, no matter if it's infamous. As for Willie Garza, it's all on him and you can add Lane (shame) Kiffin to the mix. Those guys are long gone from UT so the only thing the NCAA should do is give the Vols a warning. I don't think nothing too much will come of this.
Since: Aug 30, 2007
Posted on: September 27, 2011 9:35 pm
Report: Former Vols assistant wired cash to Lyles
Again, why is Lane Kiffin coaching... ANYTHING. He has never accomplished a damn thing as a head coach, unless I don't know about some Kiwanis League team somewhere he guided to a Church League title.
Since: Dec 23, 2007
Posted on: September 27, 2011 6:54 pm
Report: Former Vols assistant wired cash to Lyles
The guilty party is teh athlete.. He knew it was wrong... Mama said sonny boy we need to move on from here... he should have said mama.. we need to be moral and do the right thing... moma then beat the dodo out of sonny... any report of the boy knowing how to read or write,... maybe math....nah... baylor said no problem... education is secondary...


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Highland Heather Lodge
From $223 / night
Description from the owner
Description from the owner
Bedrooms: 1/
Bathrooms: 1/
Sleeps: 2/
Type: Cottage
RELAX UNWIND ENJOY AND CHILL OUT in our luxury Self -catering lodge in the heart of Perthshire in the beautiful valley of Strathearn all with private out door hot tubs. The lodge is equipped with everything you could need for an enjoyable stay and is decorated in a modern style with light decor, wooden floors and leather sofa. A feature of the one bedroom lodge is the mezzanine bedroom with double height panoramic windows to enable you to enjoy the early morning views of the mountains from the luxury of your bed. The lodge includes wet room with power showers and under floor heating. The lodge is ideally placed to enjoy the great outdoors...Read more
About the owner
About the owner
- Response rate: 65%
- Response time: Within a day
- Calendar updated: 13 days ago
Overall rating:
4.8 / 5.0
Highland Heather Lodge Comrie, Perth and Kinross, Scotland
Additional Location Information
The village of Comrie is nearby with a small selection of shops and restaurants which cater for all tastes.
There are many excellent golf courses close by with Gleneagles (Home of the 2014 Ryder Cup) a short drive away.
There is Salmon and trout fishing, water sports, horse riding and tennis available within a short drive.
A range of walks to suit al abilities from reluctant amblers to serious walkers.
Use of Crieff Hydro pool and leisure facilities(additional charge) but discounted.
A car is recommended but in the summertime a local bus can take visitors around the area. Car parking is available on-site.
More About This Location
Mountain nearby, Rural retreats


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How awareness can
News & Events
New York Blood Center abandons its research chimps – Please sign our petition!
Dr. Jane Goodall has written an open letter to the President and CEO of the New York Blood Center (NYBC) in reference to the 66 chimpanzees which the Center used in experiments and has abandoned in Liberia.
You can read Dr. Goodall's full statement to Dr. Christopher D. Hillyer, CEO of NYBC, and how NYBC has ceased oversight and financial support for these chimps.
You can also read the New York Times article and sign the petition urging NYBC to honour its ethical responsibility for the chimpanzees and reinstate funding!
JGI Canada in the news!
At 81, Jane Goodall still crusading for chimpanzees
Jane Goodall is still wild at heart


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Clay Rapada
Yankees release Clay Rapada
Apr 3, 2013, 4:06 PM EDT
After designating Clay Rapada for assignment last week the Yankees have released the left-handed reliever. Rapada is currently sidelined by a shoulder injury, but the Yankees needed the 40-man roster space more than they wanted to keep him around on the disabled list. Rapada was pretty effective for the Yankees last season, posting a 2.82…
Clay Rapada expected to begin season on disabled list
Mar 22, 2013, 12:16 PM EDT
Clay Rapada, who was very effective as a situational left-hander for the Yankees last year, is expected to begin the season on the disabled list with a shoulder injury. Rapada latched on with the Yankees last February after being released by the Orioles and appeared in 70 games, posting a 2.82 ERA and holding left-handed…
Scott Boras really thinks the Yankees should sign Rafael Soriano
Nov 5, 2012, 10:32 AM EDT
Scott Boras, you will not be surprised to hear, believes that the Yankees should sign Rafael Soriano. From Jon Paul Morosi's latest: "If the Yankees didn't sign Soriano, they wouldn't have won the AL East," Boras said flatly. "This is the value of depth. If the Yankees signed Soriano (after the 2010 season) when Rivera…
Orioles pull ahead of Yankees in 13th inning
Oct 12, 2012, 12:02 AM EDT
The Orioles have a little bit of life left. J.J. Hardy just delivered an RBI double off David Phelps in the top of the 13th inning to give the Orioles a 2-1 lead over the Yankees. It broke the team's 0-for-15 streak with runners in scoring position. Manny Machado got the inning started with an…
And That Happened: Thursday's scores and highlights
Jun 29, 2012, 5:40 AM EDT
Pirates 5, Phillies 4: All of you who predicted that A.J. Burnett was going to rattle off eight straight wins at some point this year, please cut it out because you're lying. Now if you'll excuse me, I'm gonna go piss off a bunch of Yankees fans by suggesting that Brian Cashman should trade for…
Yankees to fill Okajima void with Clay Rapada
Feb 18, 2012, 6:13 PM EDT
The Yankees were on the hunt for another lefty relief candidate after Hideki Okajima failed his physical and apparently have found one in veteran Clay Rapada, says MLB.com. Rapada, who turns 31 next month, is expected to get a minor league contract. The sidearmer had a 6.06 ERA in 16 1/3 innings for the Orioles…
Tweet of the Day: Cut by Orioles, Clay Rapada needs work
Feb 6, 2012, 2:14 PM EDT
Baltimore trimmed reliever Clay Rapada from the 40-man roster this morning to make room for Jason Hammel and Matt Lindstrom, so the 30-year-old left-hander is now looking for work via Twitter: anybody need a lefty… lefty are 6-67 last two years… #justsayin — Clayton Rapada (@pada5something) February 6, 2012 Rapada correctly notes that left-handed hitters…
Rangers drop Clay Rapada from roster, add Mark Lowe
Oct 27, 2010, 2:19 PM EDT
San Francisco made no changes to its roster for the World Series, but Texas made a minor switch in the bullpen by dropping left-hander Clay Rapada and replacing him with right-hander Mark Lowe. Rapada was added to the ALCS roster to help combat the Yankees' left-handed hitters, and particularly Robinson Cano, but he failed to…
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This evening the Montgomery County High School SBDM Council selected Mr. Rocky Franz to serve as the Principal at MCHS. Mr. Franz is a familiar face to students, parents, and staff at the high school, where he previously served as an assistant principal. Please join us in welcoming Mr. Franz into his new position.
Jump Start Kindergarten at Mapleton Elementary is scheduled for Monday, July 27th - Wednesday, July 29th. The program will run daily from 8:00 a.m. until 12:00 p.m. Registration packets will be mailed to all incoming kindergarten students who are currently enrolled to attend in the fall. If you would like for your child to participate or if you have questions regarding the program, please contact Leslee Toy at 859-497-8752 or by email at email@example.com
Read more about what it takes to be a Kentucky School of Distinction.
Kentucky Schools
Kindergarten Monday, August 10,2015 from 5:30 – 7:00 Meet in the gym first for an introduction to our school by Mrs. Harris and informational booths for transportation, food service, and programs.
First through fourth grades Tuesday, August 11,2015 from 5:30 – 7:00 Parents are welcome to go directly to classrooms. There will be informational booths set up in the gym from 5:30-7:00.
Click here to view details about the Montgomery County Public Library Summer Reading Program. Ages 18 months through high school
Find out about your Super Powers!
The School Nutrition Services Director has shared the summer feeding sites for students across the County. Updates to the list will be made as needed, so please check before going. Click here to view the sites and times.
A new Mapleton 4th grade tradition, students performed learning songs a insturmental solos.
Students take on the hero's challenge to use good work habits at home and at school!
MoCo High School Heroes in sports as well as outstanding character and academics share their secret to success. Meanwhile, Spidey encourages good behavior.
Mapleton's Academic Team placed 2nd in the quick recall tournament and 1st in the FPS tournament.
May 29, 2015 Last Day of School
August 13,2015 First Day of the New School Year!!!!!
Montgomery County winners of the Jim Claypool Conservation Art contest were all Mapleton students this year! First place Ollie Fagenbush, second Jake Lawill, and third place Shyanne Lawson . Shirley Ginter, Art teacher at Mapleton, was named Outstanding Conservation Teacher of the Year in the Montgomery County Conservation District for her dedication to teaching conservation of natural resources through art.
National author, Mark Wayne Adams; a native of Dawson Springs, Kentucky, shared his talent with all Mapleton students as he talked about writing, illustrating, and good work habits. Many students left with signed copies of books as part of his program to encourage young readers.
Mapleton Elementary Science Club attended the 2015 Kentucky Youth Energy Awards in Frankfort where they were recognized for an outstanding 2014-2015 energy program. Six students represented the cub of 52 children. These six students had the highest participation as the club worked on their project, Energy Rocks. Mapleton 3rd and 4th grademembers lead others in an energy education program, school wide recycling, Science Fair, Energy Audit of Mapleton, finding ways to make our school more energy efficient and a reusable bag campaign. (Pictured Ben Thomerson, Kiah Goodpaster, Emily Zink, Jacob Mullins, Ian Morales, Hallie Conley. Standing behind them is club sponsor Sheila Baker.)
The school calendar for the 2015-16 school year has been approved. Click here to view.
Student Technology Leadership Program Competes on the state level with several projects.Students traveled to Morehead and Lexington this year.


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Rolling Plains UMC is starting an Evening MOPS group for mothers of young children through Kindergarten. The first meeting/registration will be Friday, May 6th at 6:30pm. For more information call the Church at 453-4192.
On Sunday, April 3rd at 3pm at Roscoe UMC. This year six choirs will sing two anthems en masse - "Fairest Lord Jesus" and "Upon This Rock". For more information call 740-622-7780.
On April 1st & 2nd at the Colony Square Mall. Kids can meet Bard the Bunny on Saturday Only from 11am-1pm. Walk through the Kiser Colon, an 8 ft tall 20 ft long giant model of the human colon. There will be free blood pressure & blood sugar screenings, free body fat analysis, free diabetic foot screenings, & free food preparation demonstrations.
On Thursday, June 23 and Friday, June 24th from 9-3 at Friendly Hills Grange Camp, 5880 Friendly Hills Rd in Zanesville. The cost is $20 & the deadline is May, 20th. Register at www.muskingumwcd.org. For more information call Nichol Hafer at 454-2027.
On Saturday, May 14th at Zane's Landing Park with registration beginning at 9am & the walk starts at 10am. To register a team or become a sponsor visit http://greatstrides.cff.org
Held at First Christian Church, 3000 Dresden Rd. (at Military Rd) from 8am-2pm. Parking in the rear. Lots of items.
Held at 23720 Airport Rd. Coshocton Ohio beginning at 9am.
Sponsored by the Muskingum Soil & Water Conservation District to locate, measure & document area's big trees. Free and open to public. Trees counted on all land in Muskingum County. Contact Clayton Rico at 740-454-2027 or 454-2767 for more info. Deadline is April 1, 2011.
Sunday, March 20th from 4-6pm at the Muskingum Valley Old Timers Club. If you have any questions call Doug Staker at 819-5930.
On April 14th from 11am-1pm at the Welcome Center, 205 North 5th St in Zanesville.
Community Resource Day is an opportunity for you to come, meet, and learn about a wide variety of service agencies and their professionals from the Muskingum County area all under one roof!