text:
Original recipe yields 6 servings
Amount per serving ({{servings}} total)
Based on a 2,000 calorie diet
Ready In
Wow, was this ever good! I followed the recipe exactly and let it marinate for over 8 hours. The flavors really came through and it browns nicely on the grill with the addition of honey in the...
Excellent recipe! Instead of the individual margarita ingredients, i used a pre-mixed margarita (tequila and all) that i had in the fridge. I marinated for almost 24 hours, which REALLY allowed...
My chicken marinated 6 hrs and I could barely pick up on a lime flavor. There are others on this site with fewer ingredients that have more flavor. I won't make this again


text:
Amate Studios Designer's Flat Diamond Choker Necklace
Additional Information
Make wonderful jewelry creations that will keep you in the spotlight with the Amate Studios Designer's Flat Diamond Choker Necklace. This lead free pack contains one adjustable, flat diamond shaped choker necklace base that is great to use with resins, UTEE, polymer clay, paper, fabric, beads and more. Choose from a variety of shapes and sizes and use them as bases with colorful beads, pendants and stones to create gorgeous necklaces. Each piece is individually handmade and may slightly differ from others.
- Brand: Amate Studios
- Includes one adjustable choker necklace
- Available in a wide variety of shapes and sizes
- Lead free

subset: commoncrawl


text:
Saint Francis nurses fear for jobs, patient services
Dec. 19, 2013
Most Viewed
Email this article
Saint Francis nurses fear for jobs, patient services
In the midst of the holiday season, the future is uncertain for Saint Francis Hospital and Health Centers employees but they will continue to focus on patient care, officials and workers said.
A link to this page will be included in your message.
Real Deals
Shop and save locallyGET DEALS NOW
Get it all
sign up for delivery
View the last seven days
- Yesterday, Jul 02
- Wednesday, Jul 01
- Tuesday, Jun 30
- Monday, Jun 29
- Sunday, Jun 28
- Saturday, Jun 27
- Friday, Jun 26
See our paid archives for news older than a week.
Latest Blogs


text:
Real, honest-to-goodness holograms are a thing now
If you're retiring soon, take these steps now
Join the NASDAQ Community today and get free, instant access to portfolios, stock ratings, real-time alerts, and more!
For Immediate Release
Chicago, IL - March 5, 2012 - Zacks.com announces the list of
stocks featured in the Analyst Blog. Every day the Zacks Equity
Research analysts discuss the latest news and events impacting
stocks and the financial markets. Stocks recently featured in the
blog include
Ford Motor Co.
General Motors Co.
Peugeot Citroen
Humana Inc.
) and
CNO Financial Group Inc.
Get the most recent insight from Zacks Equity Research with the
free Profit from the Pros newsletter:
Here are highlights from Friday's Analyst Blog:
Ford Europe Predicts Heavy Loss
Ford Motor Co.
) revealed that it is likely to lose between $500 million and $600
million in 2012 in the 19 European markets covered by the automaker
owing to the ongoing debt crisis in the region. The figure compared
with a meager $27 million loss recorded by the company in 2011. In
the fourth quarter of last year, the loss amounted to $190
While releasing the fourth quarter results, Ford projected
industry volume (including medium and heavy trucks) of 14.0 million
units-15.0 million units for full year 2012 in Europe. However,
industry-wide sales in the region are expected to reach the lower
end of the forecast, according to the Chief Financial Officer of
the company, Lewis Booth.
The present Euro zone financial crisis affected the operations
of many global automakers, especially Ford and
General Motors Co.
). Both automakers have significant exposure to the market.
The car dealers in Europe are trying very hard to entice
consumers with steep discounts and other sales promotions, which
will put a downward pressure on their margins. The West European
car market is expected to decline to 11 million units in 2012.
A few months back, GM's European arm, Opel, revealed that it
expects to report an operating loss of €1 billion ($1.3 billion)
due to fewer than anticipated car sales. The unit expects to sell
1.4 million vehicles in 2012, which are about 100,000 units less
than the earlier projected sales.
In order to reverse the 12 years of losses in Europe (totaling
more than $12 billion), particularly from the Opel brand, GM has
recently formed a global allowance with
Peugeot Citroen
). The alliance will help both the automakers reduce at least $2
billion in costs.
Ford, a Zacks #3 Rank (Hold) stock, posted a 34% fall in profit
to $797 million or 20 cents per share (before special items) in the
fourth quarter of 2011 from $1.20 billion or 30 cents per share
(before special items) in the same quarter of 2010. With this, the
automaker has missed the Zacks Consensus Estimate by 7 cents per
share. Total revenue during the quarter grew 6.5% to $34.6 billion.
It was higher than the Zacks Consensus Estimate of $31.8
For full year 2011, Ford reported a 19% decline in profit to
$6.12 billion or $1.51 per share (before special items) from $7.58
billion or $1.91 per share in 2010. However, the company's profit
failed to meet the Zacks Consensus Estimate of $1.84 per share.
Revenues in the year increased 13% to $136.3 billion. It was higher
than the Zacks Consensus Estimate of $128.2 billion.
Humana Downgraded to Neutral
We have downgraded our recommendation on
Humana Inc.
) to 'Neutral' based on the company's high operating expenses and
increased dependence on Medicare Advantage earnings. The company
also faces ample pricing and competitive risks.
Humana's fourth-quarter operating earnings came in at $1.12 per
share, lagging the Zacks Consensus Estimate of $1.20 and the
year-ago earnings of $1.14. The fourth quarter earnings of $294
million was also below the year-ago earnings of $310 million.
Humana has been regularly acquiring companies to expand its
business platform. The Concentra acquisition has allowed the
company to enter the primary care market on a national scale.
Additionally, the acquisitions of AMS and MD Care will expand the
company's Medicare coverage. Moreover, the acquisition of Antiva
Health, announced in December 2011, is expected to strengthen
Humana's clinical management.
Besides, Humana has a strong Medicare business, which is further
expanded through collaborations. The Medicare Part D PDP plan
launched in collaboration with the Wal-Mart Stores in October 2010
expanded the company's individual Medicare stand-alone PDP
membership by 52.1% to 2.54 million at 2011-end, compared with 1.67
million at 2010-end.
Moreover, both the Humana Walmart-PDP and Humana's alliance with
CNO Financial Group Inc.
's (
) subsidiary Bankers Life and Casualty Company to offer Humana
Medicare products will enhance the company's membership in
prescription coverage plans and mail-order drug business. Humana is
already the fifth-largest health insurer on enrollment basis.
Want more from Zacks Equity Research? Subscribe to the free
Profit from the Pros newsletter:
About Zacks Equity Research
Zacks Equity Research provides the best of quantitative and
qualitative analysis to help investors know what stocks to buy and
which to sell for the long-term.
Continuous coverage is provided for a universe of 1,150 publicly
traded stocks. Our analysts are organized by industry which gives
them keen insights to developments that affect company profits and
stock performance. Recommendations and target prices are six-month
time horizons.
Zacks "Profit from the Pros" e-mail newsletter provides
highlights of the latest analysis from Zacks Equity Research.
Subscribe to this free newsletter today:
About Zacks
Zacks.com is a property of Zacks Investment Research, Inc.,
which was formed in 1978 by Leon Zacks. As a PhD from MIT Len knew
he could find patterns in stock market data that would lead to
superior investment results. Amongst his many accomplishments was
the formation of his proprietary stock picking system; the Zacks
Rank, which continues to outperform the market by nearly a 3 to 1
margin. The best way to unlock the profitable stock recommendations
and market insights of Zacks Investment Research is through our
free daily email newsletter; Profit from the Pros. In short, it's
your steady flow of Profitable ideas GUARANTEED to be worth your
time! Register for your free subscription to Profit from the Pros
for information about the performance numbers displayed in this
press release.
Follow us on Twitter:
Join us on Facebook:
Disclaimer: Past performance does not guarantee future results.
Investors should always research companies and securities before
making any investments. Nothing herein should be construed as an
offer or solicitation to buy or sell any security.
Media Contact
Zacks Investment Research
Enter up to 25 symbols separated by commas or spaces in the text box below. These symbols will be available during your session for use on applicable pages.
You have selected to change your default setting for the Quote Search. This will now be your default target page;
unless you change your configuration again, or you delete your
cookies. Are you sure you want to change your settings?


text:
He told a joint press conference with Mr Arafat at Downing Street: "A viable Palestinian state, as part of a negotiated and agreed settlement, which guarantees peace and security for Israel, is the objective."
The talks, set up before September 11, took place against a drive by the US to push Israel and the Palestinian authority beyond the present shaky truce to the negotiating table.
Mr Arafat called for an "immediate" resumption of talks with the Israeli government on a peace settlement.
Mr Blair reminded journalists that he had visited Gaza and spoke expressively about the injustices suffered by the Palestinians. He rejected a suggestion that his enthusiasm for the Palestinian cause was influenced by the attacks on September 11.
The Israeli-Palestinian conflict is one of the main causes of resentment in the Muslim world towards the US, which has long backed Israel.
The US and Britain are both anxious to reduce the tension caused by the Israeli-Palestinian conflict and to blunt the message of Osama bin Laden, who in a videotaped statement last week identified himself with the Palestinian cause.
Mr Blair's being pictured shaking hands with Mr Arafat will help to counter Bin Laden's propaganda move. Mr Blair told the conference that Bin Laden did not speak for Palestinians or their cause.
Mr Arafat, though in a delicate position because of Islamist support for Bin Laden within his Palestinian authority, repeated his condemnation of suicide attacks on America and described such violence as contrary to Islam.
Mr Blair was scheduled to hold further talks by phone last night with the Israeli prime minister, Ariel Sharon. A meeting between the two will take place in London next month.
An Israeli government source said that, in spite of jitters about the consequences for Israel of the new international landscape, Mr Sharon was content that Britain was keeping Israel in the loop in its discussions with the Palestinians.
The foreign secretary, Jack Straw, phoned his Israeli counterpart, Shimon Peres, on Saturday as part of the preparations for Mr Arafat's visit.
Mr Blair and Mr Arafat discussed new US proposals that set a framework for discussions on the future of Jerusalem, which both peoples want as their capital; the future of Israeli settlements on the West Bank and Gaza; territorial boundaries; and the right of return of Palestinian refugees.
Mr Blair told Mr Arafat he had to work harder to produce an end to, or at least a decrease in, violence for talks to begin.
The prime minister said he supported the UN resolutions on the Israeli-Palestinian conflict, which, among other things, call for Israel to leave the occupied territories, the West Bank and Gaza. He said: "The end we desire _ is a just peace in which Israelis and Palestinians live side by side, each in their own state, secure and able to prosper."
Mr Blair, who was left in no doubt during his visit to the Middle East last week about the animosity generated in the Muslim world by Israeli-Palestinian conflict, said there was a "renewed sense of purpose to move things forward".
Mr Arafat used the conference to call for a resumption of peace talks: "I call on the Israeli government to immediately rejoin us in the permanent status negotiations so we can reach a just, comprehensive and lasting solution to all issues on the agenda. That is an agreed agenda: Jerusalem, settlements, borders, refugees, security, water."
He has made similar calls over the past few months, but has met with the same Israeli response: no talks without a complete end to Palestinian violence against Israelis.
Mr Peres said yesterday: "What we have to do is to start introducing the complete ceasefire, then we can start completing [peace] negotiations."


text:
MS Eugenie
Line: Discover Egypt
Tonnage: Unknown
Length: Unknown
Total Crew: Unknown
Occupancy: Unknown
Rating: stars
The luxurious Nile Steamer Eugenie epitomises all the class and glamour of a more elegant age with warm wood panelling throughout, plush red and green furnishings, velvet curtains, tasteful artefacts and antique furniture.
Food and Drink
- Bimini Bar
- Buffet
- Lounge Bar
- Shops
- Video Room
- Card Room
- Library
- Massage
- Sauna
- Steam Room
- Sun Deck
- Whirlpool
No decks found.
Lake Nasser Cruise - Abu Simbel to Aswan - Egypt & Red Sea
Lake Nasser Cruise - Aswan to Abu Simbel - Egypt & Red Sea
No reviews found.


text:
Select Local Merchants
Brenda Athletic ClubsRead MoreSince 1978, Brenda Athletic Clubs has stood out from other gyms for its staff?s focus on offering all the amenities of a modern fitness facility while still fostering an inviting atmosphere. Its founder, Al Brenda, believed in fitness programs for all age groups, a mantra that the club continues today with youth fitness programs, including basketball clinics and yoga lessons, as well as a SilverSneakers fitness program for seniors. In addition to tennis, swimming, and standard strength and cardio equipment, the fitness centers supply its members with an ample amount of group classes including cycling, Zumba, and kickboxing. Their newest location, aptly named Yes You Can!, is designed to be an elite training studio specializing in smaller group classes such as rowing, cross training, and seven more specialty classes.3360 North Highway Suite AMerced, CA US
Active4NutritionRead MoreWhen planning her client's diets, holistic health coach Kristina strives to acquaint people with new foods and habits, gradually eliminating cravings and forging a lifestyle that her website calls "free of denial." She views herself as proof of this program's success, having lost weight by undergoing training at the Institute for Integrative Nutrition and adjusting her eating behaviors. Through Live Naturally with Kristina, she helps others change their nutrition and fitness outlook with personalized guidance. Her 60-day and 6-month programs both begin with a complimentary breakthrough session, where she plans unique approaches to each person's goals. The programs cover one-on-one coaching, wholesome recipes, and tutorials on tasks that shape a healthy lifestyle, including grocery shopping and cleaning out your kitchen. Additionally, Live Naturally with Kristina sets up group gatherings and an online community to provide social support.1361 East 27th StreetMerced, CA US
Sierra Vein & Vascular InstituteRead MoreLed by Dr. Mehrdad Amirhamzeh, a board-certified cardiovascular and thoracic surgeon, Sierra Vein & Vascular Institute's medical staff aims to clear up skin's appearance and vanquish vein disease. Non-invasive treatments such as sclerotherapy and VNus Closure—an outpatient procedure using radio frequencies—can target cosmetic concerns while abating serious concerns such as leg ulcers or kisses from cobweb-seeking vacuums. The staff consults with patients to craft plans focused on minimal downtime and quick recovery. Dr. Amirhamzeh maintains affiliations with many state, national, and intergalactic medical societies, including the Society for Vascular Surgery and the American Medical Association.177 W El Portal DrMerced, CA US
Gateway Optometric CenterRead MoreDon't skimp on the quality of care for your eyes. Make the windows to your soul last a lifetime with the high-quality care at Gateway Optometric Center in Merced. Gateway Optometric Center will help pick out a pair of glasses to help frame your face. If you're so inclined, they also offer terrific contact lenses. To prevent long waits and accommodate guests in a timely manner, this vision center provides appointment-only services. If you're short on cash, take care of business with one of many major credit cards. Whether you're in need of urgent eye care of just a yearly checkup, Gateway Optometric Center has you covered.3371 G StMerced, CA US
Park Avenue Physical TherapyRead MoreWhen you have a medical ailment in Merced, the professionals at Park Avenue Physical Therapy are only a call away. When you're seeking medical care, such as medical checkups, this medical facility is here for you. There is a relaxing massage with your name on it waiting for you at this clinic. If your preference is an alternative treatment, such as physiotherapy, this clinic is the place for you. Park Avenue Physical Therapy handles all of your coughs, colds, allergies, and illnesses, so make sure to come here for the best in treatment and care.2808 Park AveMerced, CA US
Pearl Family DentistryRead MoreA professional teeth cleaning from Pearl Family Dentistry in Merced is the first step to keeping both your teeth and gums healthy. This dental clinic will help you look your best with cosmetic dentistry with such services as fillings, check up, cleaning, crowns and veneers, teeth whitening, and Invisalign. When you come in today, you won't even have to worry about an appointment. Walks-ins are accepted. The dentists at Pearl Family Dentistry are ready to take on your latest oral challenge, from cavities to tooth aches. Give them a call today.645 W Olive AveMerced, CA US


text:
Top Posts
Latest Posts
What ankle problems? Ray Allen plays 46 minutes, looks good
Jun 4, 2012, 8:03 AM EDT
At the start of the Eastern Conference finals, Ray Allen was moving around the court like Betty White. Battling bone spurs in his ankles, he wasn't moving crisply to get open and when he did get a look there was no lift in his legs and shots clanged off the rim. He was even missing…
Report: Heat to activate Chris Bosh for Game 5
Jun 4, 2012, 2:27 AM EDT
Miami has sorely missed Chris Bosh. They could use his size on defense to create problems for Kevin Garnett. Their pick-and-roll desperately misses him because right now nobody respects the pick setter, everyone can focus on Dwyane Wade or LeBron James. But Miami may not have to wait much longer. There is a report that…
Celtics-Heat Game 4: Boston out executes Heat, evens series 2-2
Jun 4, 2012, 1:05 AM EDT
Boston owned the first half with a sharp offense. Miami played defense for the first time since their plane landed in Boston in the second half and tied it up. But with everything on the line at the end of the game and in overtime it came down to execution, and the veteran Celtics were…
Celtics-Heat Game 4: Rajon Rondo punks Heat in halftime interview on whining about officiating
Jun 4, 2012, 12:42 AM EDT
Rajon Rondo, after dropping 10 assists in the first half of the Celtics' Game 4 win over the Heat, spoke to ESPN reporter Doris Burke for the standard halftime interview. And took a shot at the Heat right off the bat. "They're complaining and crying to referees in transition." That's pretty succinct. Rondo's correct in…
When the process matters: Why Charlotte should trade the No.2 pick
Jun 3, 2012, 7:00 PM EDT
Let's start off with some instant rebuttal to the premature outcry that headline above is going to muster. First, the basics. The Charlotte Bobcats, in a continuing pattern regarding their awful, horrendous, terrible franchise history, lost the lottery's No.1 pick despite a 1-in-4 chance to land Anthony Davis. The Bobcats are an awful, awful basketball…
The Bulls, Steve Nash, Jason Kidd, and walking the walk vs. talking the talk
Jun 3, 2012, 5:30 PM EDT
See, here's the problem with the superstar team-up era. The Chicago Bulls have put together a team that features a perennial MVP candidate at 23, an All-Star wing defender who can shoot, a hyper-active emotional powderkeg with some offensive skills built in at seven-feet, a deep bench, some microwave scorers… and Carlos Boozer. (No one's…
Blazers may just decide to make interim coach, GM permanent
Jun 3, 2012, 4:01 PM EDT
Portland's year-long, on-and-off search for a GM has been as tidy and clean as a home on Hoarders. It's a mess. And after all that it may end up falling back to the guy who has been doing the job the whole time — Chad Buchanan. The "interim" guy who has rocked the job while…
Celtics-Heat Game 4: The bizarre development of the Boston offensive juggernaut
Jun 3, 2012, 2:00 PM EDT
It makes no sense, you understand. We're talking about throwing away not just the stats, forget the stats. We've seen it. We've seen the Boston offense not only struggle, but look absolutely apoplectic for six months. That Sixers series was something out of a Rob Zombie film on offense. It wasn't just gross, it was…
Report: Suns have interest in Alonzo Gee
Jun 3, 2012, 12:30 PM EDT
Alonzo Gee is what you might call a value free-agent this summer. The Cavs forward has athleticism, youth on his side, a versatile skill-set, and strong upside. But he hasn't played well enough or under a big enough microscope to carry with him serious buzz. So teams are going to get their shot at making…
Celtics-Heat Game 4: Chris Bosh still out
Jun 3, 2012, 11:00 AM EDT
Same story, different day. Chris Bosh will not be riding to the rescue of the Miami Heat as they try and put the chokehold on the Celtics in Game 4 in Boston.ESPN reports: Heat coach Erik Spoelstra said Saturday that Bosh won't play Sunday and reiterated the All-Star forward has not yet advanced far enough…
Quote of the Day: Pop was there, he saw it.
Jun 3, 2012, 9:00 AM EDT
Reporter: "It seemed like [Durant] took over." Popovich: "It didn't 'seem' like that. That was a fact. I was there. I saw it. He was great." — Alex Kennedy (@AlexKennedyNBA) June 3, 2012 And that's why Pop's the best. Durant's performance in Game 4 was not the first dominant performance Popovich has seen in the…
Spurs need Duncan to step up if they want to reach the Finals
Jun 3, 2012, 12:41 AM EDT
Tim Duncan's legacy is largely beyond reproach. The man has four NBA titles to his name, is one of the two greatest players of his generation, and just recently became the all-time playoff leader in blocked shots. And yet, his play in the Western Conference Finals hasn't been all that special. Duncan will get a…
Thunder even Western Conference finals with Game 4 win over Spurs
Jun 2, 2012, 11:59 PM EDT
The reason that home-court advantage makes a difference in the NBA postseason is because of the fact that the role-players, bench guys, or simply lesser-known producers tend to play above their average capabilities with the home crowd behind them. That was certainly the case in Game 4 of the Western Conference finals in Oklahoma City, where the…
Report: Suns to pursue Deron Williams. What, is Magic Johnson unavailable?
Jun 2, 2012, 9:00 PM EDT
The New York Daily News reports that if Steve Nash leaves the Suns in free agency, the Suns will make a bid for Deron Williams. "If they lose Steve, then they plan to go after Deron, hard," said a person with knowledge of the Suns' plans. "They know he loves golf and they're going to…
Video: This should get you suitably excited for Thunder-Spurs Game 4
Jun 2, 2012, 7:30 PM EDT
No words necessary. Get your popcorn. Via @calebjsaenz on Twitter.
Celtics-Heat Game 4: Celtics can survive a LeBron onslaught, can Heat survive another Rondomination?
Jun 2, 2012, 5:42 PM EDT
Here's the secret to this series, and the Celtics' postseason in general. Kevin Garnett getting points off the pick and pop and in the post over Ronny Turiaf and yelling and barking and cursing is nice. Paul Pierce getting an inefficient number of points per FGA is fine. Ray Allen hitting some in-between freezeouts is…
LaMarcus Aldridge was hospitalized with deadly blood virus
Jun 2, 2012, 3:23 PM EDT
This is scary. As Kevin Garnett would say, "really [expletive] scary." Trail Blazers All-Star forward LaMarcus Aldridge found himself in the hospital this week with a potentially deadly blood virus. He wrote about it in his blog on trailblazers.com (hat tip to Blazers Edge). On Saturday I came down with a blood virus. I quickly…
Report: Warriors targeting Iguodala, Gay, Granger, unicorns, hippogriffs
Jun 2, 2012, 2:00 PM EDT
The Warriors at this point might as well put up a big neon sign outside their offices that read "TRADE MARKET FLEA SALE TODAY!" Ever since they went into tank mode, they have made it known that their players are available for trade and that they want a small forward in return. And by landing…
The New Orleans Hornets and a matter of serendipity, not conspiracy
Jun 2, 2012, 12:30 PM EDT
Maybe they're right. Maybe the league, in the face of unfathomable depths of reason to avoid the concept like the plague (which I have outlined here), really did rig the 2012 NBA Lottery in order to help the Hornets after a rough year, or dot the i's on the sale of the team to Tom…
Thunder-Spurs Game 4: Let's get serious
Jun 2, 2012, 11:00 AM EDT
Seriously, this is the most serious of seriousness. This is the business. This game is monstrous. All those games before that were big? No, this one is big. BIG. Like, those commercials big. Thunder-Spurs Game 4 is going to have dramatic ramifications either way. If the Spurs win, the Thunder's Game 3 win is meaningless…
More Top Posts
- Report: Pacers agree to four-year, $44 million contract with Monta Ellis 22
- Report: Greg Monroe signing a maximum contract with Bucks 56
- Lakers, Knicks struggle on hectic first day of free agency 64
- Trail Blazers assistant coach: 'We didn't publicize it, but we lost LaMarcus Aldridge' 9
- Who is left on the board after wild first day of NBA free agency? 31
Most Commented
- Report: LaMarcus Aldridge rules out Lakers in free agent decision (112)
- Report: Carmelo Anthony feels betrayed by Phil Jackson drafting Kristaps Porzingis (98)
- Kevin Love will return to Cavaliers, contract is reportedly $110 million over five years (80)
- Phil Jackson says scout told him it was a 'once-in-a-lifetime opportunity' to draft Kristaps Porzingis (66)
- Lakers, Knicks struggle on hectic first day of free agency (64)
- L. Aldridge (5440)
- D. Wade (4940)
- L. James (3889)
- J. Embiid (3791)
- G. Monroe (3343)


text:
It might make you nauseous, but it's also hilarious: Asian Poses.
Via Adam Schokora (via Twitter).…
It might make you nauseous, but it's also hilarious: Asian Poses.
Via Adam Schokora (via Twitter).…
I haven't noticed any online English language mentions of Shanghai comedian Zhou Libo (周立波) yet, but he clearly deserves a bit more attention. His DVD, 笑侃三十年, has been selling like hotcakes in DVD shops across Shanghai for weeks, and I hear his upcoming live performances are selling out.
You could say his act is "comedy with Shanghainese characteristics" because 笑侃三十年 is Zhou's humorous take on the changes Shanghai has experienced in the …
I was helping a Chinese friend with her English, and was very interested to read the following dialogue in her book. (I have preserved the grammar and punctuation of the original, but I didn't feel like writing "[sic]" everywhere.)
The dialogue:
A: Your English is not like American English.
B: Oh, I see. What I speak is true American English, but it is not standard American English.
A: What kind of English is it?
B: It is Black English.
My friend Sean has a hilarious post up about cultural differences compounded by generation gaps in China. This particular drama revolves around toilet paper. Here's an excerpt:
By the time the night was finishing up and the massage was over, it was quite late, around 10:30pm. The parents live in a slightly remote part of Shanghai, only accessible by bus or taxi, and they always refuse to take a taxi because its too expensive (even if I offer to
Lisa Movius, an American that has been in Shanghai for almost 10 years, has written up some thoughts on the local language and culture in her post, Beleaguering the Shanghainese.
Some excerpts:
I also no longer think that Shanghainese are snobby. Somewhat, and some of them are, but not hugely more than anywhere else. The Shanghainese are proud, and they are defensive. That a scruffy, disparate batch of immigrants and refugees could have fused such a coherent urban
I read this article on Discovery.com last week: Telling Bad Jokes Invokes Hostility, Violence. It prompted me to reflect upon my struggles with humor in foreign languages, and in English too.
Random observations:
A Chinese friend of mine told me that at her workplace, there was a fund-raising effort going on for the victims of the recent earthquake. Most employees contributed 100 RMB. My friend wanted to give a bit more, so she was about to put in 500 RMB when a co-worker pulled her aside.
"What are you doing?"
"I'm giving 500 RMB."
"Everyone else gave 100. The boss only gave 300. Who do you think you are, giving 500?"
My …
Micah posts two hilarious maps of China (Chinese required):
Sorry, I'm a bit too busy lately to translate this, but it's quite revealing culturally, so if you're a student of Chinese, it's worth it to get out your China map and a dictionary.
Unkind as it may sound, I got a huge kick out of the labels placed by both groups on the Wenzhounese. (I need to blog someday about …
I got several comments on the Deaf, Not Dumb post (one comment actually on the site) relating to Alice's facial expressions. The observation was that Alice seems to be much more expressive when she signs than the average Chinese person is during conversation.
I can understand this point. I remember when I first arrived in China and was still learning to communicate in Chinese, I was often told, "你的表情很丰富" (your [facial] expressions are …
It's Monday, and it's the day of the Super Bowl in China. Thanks to our good friend time difference, we watch the Super Bowl at around 7am on Monday morning here in China. (What time could be better, right?)
In case you missed the ChinesePod episode on the Super Bowl, "Super Bowl" in Chinese is 超级碗. Literally, it means (brace yourself for this)… "super bowl."
Somehow this feels wrong and fake and anticlimactic and too easy to …


text:
Prices, specials, features and availability subject to change.
Contact for details
The apartment home you have dreamed about is nestled on a peaceful suburban hillside less than five minutes from the Dayton Mall and I-75. This small, beautiful, well-landscaped community is managed by the Sterling Apartment Group. Rated best maintenance in town! Our outstanding amenities and unsurpassed service always exceed your expectations. A better way of living that's affordable.
No Pets. Call for service animal policy.
100 units
Monday-Friday: 9:00am-5:00pm
Saturday: 9:30am-3:00pm
Sunday: Closed
Apartment Guide
Don't have a Rent.com account? Create one.
Creating an account allows you to acccess your saved and contacted properties on any device. Already have an account?
Log In


text:
June 2011, TruckingInfo.com - Feature
by Rob Moseley, Smith Moore Leatherwood LLP
Tags: Drivers
As a CA. resident & a driver for a co. based in CA. how does this affect me as CA. passsed a written consent law for obtaining credit reports ?
We offer e-newsletters that deliver targeted news and information for the entire fleet industry.
The expert, Mark Betner from CITGO, will answer your questions
The expert, Rence Oliphant from Hendrickson, will answer your questions
TruckTech+ Provides Diagnostics to Fleets and Dealers
ALK Adds HOS Manager to PC Miler
Wisconsin Releases 511 Travel Information App
VentAiRator Vented Visors


text:
Reviews for B J Clancy's Restaurant
Latest Yelp Reviews
Overall Rating:
Based on 3 Reviews
Based on 3 Reviews
Carolyn T. posted on 03/13/2013
Rating & Review:
There is a birthday special here where the person whose birthday it is gets a free entree from a selected list, so I've been here a few times. Warning:... read more
Kathy V. posted on 11/28/2012
Rating & Review:
Met up here with friends for drinks and karaoke. It was a good time, but I could not for the life of me figure out the system the guy running karaoke was... read more
Lizzy B. posted on 09/07/2013
Rating & Review:
I and my companion ordered the prime rib on a Sat. night. The place was almost empty at the height of the dinner hour. His prime rib was fine. Mine was... read more
Write a Review


text:
The Great State of Arkansas Mini-Book
Take a trip to the state of Arkansas with this fun and fact-filled minibook. See Full Product Description.
Number of pages: 2 Subject: Geography and Map Skills Grade: 3 - 6 Type: Mini Books NonFiction Author: Sylvia Charlesworth File Size: 313 KB
Get Your Access to
Printables & Mini-Books
Product Details
Take a trip to the state of Arkansas with this fact-filled minibook, packed with interesting, fun-to-read information. This mini-book comes complete with an outline map, a look at state history, and fascinating facts about geography, people and places. Plus, you'll have fun-to-solve word games that reinforce what children have learned and include ways to assess comprehension.


text:
Los Angeles Clippers: J.J. Redick Goes Long Distance In Debut
J.J. Redick is one of the lesser-known names among the many to recently migrate to Los Angeles to play for the Los Angeles Clippers. Yet, those with an invested interest in the new-look Clippers will commit themselves to an occasional glance at the sharpshooting import from the Orlando Magic.
Redick's assignment is simple: run his opponent through a maze of screens, get open and charge the defense three points for loitering in the paint. In other words: bail Chris Paul out, and keep Blake Griffn and DeAndre Jordan off the free throw line. Redick's contribution is crucial to the team's success. Snipers are the most dangerous in the line of battle. No one know exactly where they are and they don't miss their target.
The trouble comes when Redick faces a team where the best player on the floor is the one standing directly in front of him: someone he can't run from, who won't play off him, and he can't defend on the other end. What was once a walk in the park for Redick would soon take a wrong turn.
He is a tough player that has lasted in the league eight years longer than many expected, but heart can only carry you so far in a league that pays handsomely for the best athletes on two feet. Unfortunately, Redick is not one of them. Yet, for the first time in Redick's career, he's playing with a true point guard, one that will create opportunities for him to do what he does best — methodically get to a spot on the floor, catch and shoot.
ChristopherBrown is an NBA writer for Rantsports.com. Follow him on Twitter @whatrockschris. Like him on Facebook- Christopher- Rant Sports
For a chance to see Redick play during the regular season, get your Clippers tickets here.
Lakers' Offseason A Success Despite No Big Move
The Los Angeles Lakers didn't land a big free agent like they were hoping, but they've made a few moves this weekend that should help them. Read More
Keeping Reggie Jackson Was A Must For Pistons
The Detroit Pistons have re-signed PG Reggie Jackson to a five-year, $80 million contract. Here's why the Pistons had to get the deal done. Read More
Bass Will Be Perfect Fit For Lakers
The Los Angeles Lakers and free agent forward Brandon Bass have reportedly come to an agreement on a contract. Find out why Bass gives the Lakers exactly what they need. Read More
Mavericks, Lakers Discussing Lin Sign-and-Trade
The Dallas Mavericks are getting desperate for help at the point guard position. Read More
5 Timberwolves Who Should Be Shown the Door
Here are five players who the Minnesota Timberwolves should show the door this offseason. Read More
Williams Makes Zero Sense For Lakers
The Los Angeles Lakers reportedly agreed to a contract with last year's Sixth Man of the Year, Lou Williams. Find out why Williams doesn't make any sense for the Lakers. Read More
Hawks Will Not Be As Good in 2015-16
The Atlanta Hawks will take a step back in the win column next season. Read More
5 Best Available Free Agents For The Heat
Take a look at the best available choices for the Miami Heat. Read More


text:
Kava Bowl in the Form of a Turtle (Darivonu), early 19th century
Wood; L. 22 in. (55.9 cm)
The Michael C. Rockefeller Memorial Collection, Bequest of Nelson A. Rockefeller, 1979 (1979.206.1579)
The preparation and drinking of kava, a mildly narcotic beverage, are central elements of Fijian culture. Carved in the form of a turtle, which seems to glide effortlessly through the sea, this vessel was used to serve kava at communal ceremonies. The form of Fijian kava ceremonies and serving vessels appears to have changed significantly beginning in the late eighteenth century. Prior to this, kava was consumed primarily by religious specialists and initiated men from small shallow vessels, which were often figural in form, or from small, leaf-lined pits in the ground.
In the late 1700s, Tongans and Samoans, who originally arrived as warriors and later settled among the Fijians, introduced a more secular kava ritual in which groups sat around a large, round kava bowl. Likely created in the early 1800s as the two types of kava rituals began to merge and become a distinctively Fijian cultural institution, this work, which combines the figural imagery of early kava vessels with the larger scale of later kava bowls, represents the adaptation of an ancient form to a dynamic and evolving tradition, which continues today.


text:
Enlarge Cover
Multnomah Books | May 11, 2000
| 192 Pages
| 5-3/16 x 8-1/4
Multnomah Books
| May 11, 2000
| 192 Pages
| 5-3/16 x 8-1/4
A fresh approach to an old topic is this unique treatise on Spirit-Controlled Living. Focusing on impulses — those pesky little "triggers" of idea and energy that may lead even well-disciplined people toward brilliant or regretted actions — Clark Cothern's third book provides readers more than "white knuckling" techniques for self-control. His step-by-step biblical model of impulse management shows how to use spontaneous anger, overspending, overeating, misplaced sexual desires, and other impulses to identify weak areas and partner with God toward achieving peace and freedom.
Clark Cothern is the senior pastor of Trinity Baptist Church in Adrian, Michigan. A frequent contributor to magazines like Decision, Discipleship Journal, and Leadership, he is also the author of Spirit Controlled Living, Detours and At the Heart of Every… More about Clark Cothern
Visit other sites on the Penguin Random House Network


text:
Halo: Spartan Strike goes official for Windows and Steam
Microsoft and 343 Industries announced Halo Spartan Strike. The twin-stick shooter game will be available on Windows/Windows Phone devices and Steam on December 12 for $5.99.
The events in the successor of Halo: Spartan Assault take place during Halo 2. Read more »


text:
By MATTHEW STEVENS
Since the moment, John Cohen was introduced as the leader of the Mississippi State baseball program he's been constantly hounded with one question.
By DANNY P. SMITH
The Eupora Eagles may have a pretty good future in clutch hitting with the underclassmen coming up through the program.
By JOEL COLEMAN
HOUSTON – It wasn't Cumberland, but for East Webster's Swayze Hollenhead, it sure felt a lot like home.
From Staff Reports
SARAH – The East Webster Wolverines pounded out 14 hits to defeat Strayhorn 16-1 on the road Friday night in the second round of the Class 2A baseball playoffs.


text:
DUNHILL-NAMIKI: MOTORITIES MAKI-E LIMITED EDITION 25 FOUNTAIN PEN. 20th century. Pen comes complete with lacquered display b...
2013 February 23-24 Estate Auction - Dallas #5129
|Sold for:
|Not Sold
|Auction Ended On:
|Feb 23, 2013
|Item Activity:
0 Internet/mail/phone bidders
2,050 page views
Heritage Auctions - Design District Annex
1518 Slocum Street
Dallas, TX
20th century
Pen comes complete with lacquered display box, eyedropper, and all original packaging and papers. Limited Edition: Only 25 pieces made. Edition 10/25
An exquisite example of the Japanese Maki-e style, this fine pen is made from precious black lacquer and decorated with sprinklings of gold dust and mother-of-pearl Raden. The pen incorporates images of wheels and flames, a homage to Dunhill's original early 1900s "Dunhill Motorities" line of automobile accessories. Nib is solid medium 18 karat gold. Pen is eyedropper filled.
Condition Report*:Two screws to the laquered case are stripped.
*Heritage Auctions strives to provide as much information as possible but encourages in-person inspection by bidders. Statements regarding the condition of objects are only for general guidance and should not be relied upon as complete statements of fact, and do not constitute a representation, warranty or assumption of liability by Heritage. Please note that we do not de-frame lots estimated at $1,000 or less and may not be able to provide additional details for lots valued under $500. All lots are sold "AS IS" under the Terms & Conditions of Auction.
View large image(s) of this item
Service and Handling Description: Requires 3rd Party Shipping (view shipping information)
Sales Tax information | Terms and Conditions
Previous Prices from Heritage Auctions
|Sign-in or Join (free & quick)


text: Devil_Dogs R?��R?�� BOOKMOBI � � - d ! ! !� "� "� $` O\ O� O� m� /V MOBI � ���� ���������������������������������������� � P �������� �������� EXTH � d Richard Alan Dickson e Grey Cat Press i demon i fantasy i young adult i science fiction i wwii i dickson i grey cat i devil dogs i corsair l Smashwords, Inc. g qFor anyone but the youngest son of the Clan Chief, slaying the fiercest flying beast on the twelve planets would be an impressive task. Not for Dras'unat. He must do so using a temperamental flying chariot from a long-dead race. But that won't stop him. He will prevail. He will take his rightful place... unless the beast, or the chariot, kills him first. , . � ����@� � � � � � b � � � Devil Dogs


text:
San Diego, CAUSA 92102
March 29, 2013
Im a model , actress and designer.
I love charity. Helping others is my favorite thing.
I change my style daily. I love coco chanel and the style of rihanna. Most of my favorite places to shop are free. I shop any and every were
Modeling, event volunteer, styling
Hello everyone my name is Jade Jennell White!
Meetup members, Log in
By clicking "Sign up" or "Sign up using Facebook", you confirm that you accept our Terms of Service & Privacy Policy


text:
Originally written on Phins Phocus | Last updated 8/31/12
Congratulations to the Miami Dolphins for providing more headlines off the field rather than on it this preseason! The preseason is finally over, but not without embarrasments exascerbated by being on national TV on Tuesdays.As tough as it was to watch last night's last preseason contest, I mustered up the courage to lower the volume a bit on my laptop so I didn't have to here about the Cowboys playmakers or here more from the playmaker himself in Michael Irvin.The Dolphins started out the contest versus the Dallas Cowboys with a beautiful three and out with the first team defense intact except for Karlos Dansby. Then entered the future of the franchise: Ryan Tannehill, protected by a very vulnerable and shaky line that held together for two series. Tannehill showed a calm and cool prescence and incredible poise for a rookie. He got rid of the ball quickly and hit his receivers often. Even though he didn't get much help or effort from Legedu Naanee, he found a way to drive the ...
Comments are closed.
What do you think?To leave a comment, you can:
NFL News
Delivered to your inbox
You'll also receive Yardbarker's daily Top 10, featuring the best sports stories from around the web. Customize your newsletter to get articles on your favorite sports and teams. And the best part? It's free!
Follow us on Twitter
|Best of Yardbarker
|NFL News
|MLB News
Today's Best Stuff
For Bloggers
Join the Yardbarker Network for more promotion, traffic, and money.
Company Info
What is Yardbarker?
Yardbarker is the largest network of sports blogs and pro athlete blogs on the web. This site is the hub of the Yardbarker Network, where our editors and algorithms curate the best sports content from our network and beyond.
|© 2015 Yardbarker, Inc. All rights reserved. Use of this website (including any and all parts and components) constitutes your acceptance of these Terms of Use and Privacy Policy. (What's New?)


text:
Fire struck a number of mainly African-American churches in five US states over the past week - in the wake of the massacre of worshippers in Charleston. At least half of the blazes are thought to be arson, and are being investigated as possible hate crimes.
|more WWRT
What We Read Today 29 June 2015
Econintersect: Every day our editors collect the most interesting things they find from around the internet and present a summary 'reading list' which will include very brief summaries (and sometimes longer ones) of why each item has gotten our attention. Suggestions from readers for 'reading list' items are gratefully reviewed, although sometimes space limits the number included.
This feature is published every day late afternoon New York time. For early morning review of headlines see "The Early Bird" published every day in the early am at GEI News (membership not required for access to "The Early Bird".).
BECOME A GEI MEMBER - IT's FREE!
Every day most of this column ("What We Read Today") is available only to GEI members.
To become a GEI Member simply subscribe to our FREE daily newsletter.
The Stimulative Effect Of Wealth Redistribution
by San Francisco Fed
-- this article authored by Bart Hobijn and Alexander Nussbacher
Policymakers often consider temporarily redistributing income from rich to poor households to stimulate the economy. This is based in part on the idea that poor households spend a larger share of their income than rich ones do. However, ample evidence suggests that the difference in spending between these groups is significantly smaller than commonly assumed. A second assumption is that redistribution through policy is more efficient than through capital markets. Whether this is true is important to consider when proposing this type of stimulus policy.
Infographic Of The Day: How NASA's Gemini Spacecraft Worked
To follow the successful series of Mercury flights, NASA planned the Gemini spacecraft for the mid-1960s.
Video of the Day:Fire struck a number of mainly African-American churches in five US states over the past week - in the wake of the massacre of worshippers in Charleston. At least half of the blazes are thought to be arson, and are being investigated as possible hate crimes.
FOREX NEWS by DailyForex
ECB To Refuse Further Greek Liquidity
With the dramatic events of Friday and Saturday still being considered, the European Central Bank (ECB) met on Sunday and decided that it would not extend Emergency Liquidity Assistance (ELA) to the Greek central bank above its current level of €89 billion.
Tsipris: Greece is Still in the Game
With d(default)-day right around the corner, Prime Minister Alex Tsipris believes he hasn't lost the battle just yet. In a television interview several hours ago, Tsipris suggested that European leaders would not have the nerve to kick his country out of the eurozone membership and that the cost of their doing so would be "enormous."
Last week saw the final trading session for the week, the month and the quarter from the perspective of these summaries. Much of that time has been pre-occupied with the Greek crisis which seems to have come to a head now.
Negotiations between Greece, the IMF and organs of the European Union came to a head on Friday. Most people had expected that some kind of 12th hour (it was that late) deal would be struck which would allow the left-wing Tsipras government to save face, but deliver some of the structural reforms that the major creditors had demanded
Greek Banks and Markets to Remain Closed
We all expected it and it has happened. Greek banks will be keeping their doors shut on Monday for an entire week. Piraeus Bank SA Chief Executive Officer Anthimos Thomopoulos told reporters of his decision Sunday after a meeting of the government's financial-stability committee.
30Jun2015 Pre-Market Commentary: Greek D-(efault) Day, Grexit Almost Assured, Markets Relatively Stable, Investors Obviously Concerned
Path to Grexit Tragedy Paved by Political Incompetence
by Barry Eichengreen,, The Conversation
Since our last episode, the crisis in Greece has escalated further. Negotiations between the government and its creditors collapsed over the weekend, and restrictions on bank withdrawals will now follow.
"Sentence First, Verdict Afterwards": The Alice in Wonderland World of Fast-tracked Secret Trade Agr
Written by Gary
U.S. stock index futures are rising as the rumor mills are churning and the charts are going to be volatile. The Greek D-(efault) day has arrived, a day after the Dow and the S&P 500 registered their worst session since October.
Markets are expected to open higher, however, technicals see further decline very possible.
June 2015 Conference Board Consumer Confidence Modestly Improves Again
Written by Doug Short and Steven Hansen
The Conference Board Consumer Confidence Index modestly improved. The market expected this index to come in at 94.5 to 99.0 (consensus 97.4) versus the 101.4 reported.


text:
My application needs configurable columns , and titles of these columns get configured in the begining, If relation database I would have created generic columns in table like CodeA, CodeB etc for this need because it helps queering on these columns (Code A = 11 ) it also helps in displaying the values (if that columns stores code and value) but now I am using Non Relational database Datastore (and I am new to it), should I follow the same old approach or I should use collection (Key Value pair) type of structure .
There will be lot of filters on these columns. Please suggest


text:
Hand and Nails
Victoria's Secret Pink Nail & Lip Collection for Fall 2013
Heads up Victoria's Secret Pink fans a new Nail & Lip Collection is on the horizon for Fall 2013. I wonder if Beauty Rush will get a kick to the curb and a new Pink Makeup Collection might take its place?!
Take a look as I'm sure you'll love some of these nail polish shades if you're a nail girl!Read More...
Butter London Backstage Basics Nordstrom Anniversary Sale Exclusive Set
Nordstrom Anniversary Sale full speed ahead chicas! And that means a Butter London Nordstrom Anniversary Exclusive Set. Butter London's Backstage Basics Set is a limited edition selection of nail essentials that will be available during Nordie's Anniversary sale for $39 both online and in store.
Here's the deets!Read More...
Bath & Body Works Black Cherry Merlot is Back
I already have a small stash of Bath & Body Works Black Cherry Merlot Hand Soap. I think I'm good enough to clean the whole of a small continent's hands with the amount I'm hoarding from the Fall 2012 release.
Honestly, at the time, when I was stocking up like the Bath & Body Works Hand Soap factory was closing down, I thought this was it. That I would never see this amazing scent again. You never can tell with BBW can you? One minute it's there, next minute it's gone, or sometimes if you get lucky it comes back.
Guess we are in luck because Black Cherry Merlot is back and I highly urge you to grab as many bottles as you can hold. I love THIS stuff. It's not the boozy scent you might think it is. This exciting mix of sweet black cherries, black raspberries, and midnight plum smells like kindergarten to me. You know, juice and cookies….
Well not the cookie part but the pure 100% juice factor is here. It's like a full bodied cherry fruit punch.
Did I mention YOU NEED IT?
Why are you still reading this?
Available now at bathandbodyworks.com or in store.
Urban Decay Nail Color in Vice and Addiction is an extremely limited edition nail polish kids. Urban Decay Polish makes a Fall 2013 in two limited edition gorgeous, decadent shades with super rich pigment and micro-sparkle that will definitely wow your nails!
And don't forget about the kick ass bottle it comes in!
Take a peek!Read More...


text:
Made From Cloth creates collaborative learning and mentoring spaces to support fashion designers in growing ecologically, ethically and economically sustainable brands.
From the blog
Your fairy fashion aunties
Send us your most pressing or trivial questions about anything related to growing your fashion brand and we will go on a hot pursuit to get you the answers you need.
Storytelling: The key to creating a cohesive collection
Collection planning is like storytelling. If done properly, you will not only appeal to your target customer, but make them want to put themselves right in the middle of the story.
How to keep your fashion press release at the top of the editor's inbox
Knowing how to format your press release to catch the eyes of a fashion journalist could be the key to catapulting your publicity campaign.


text:
RIOT Middle School Camp 2015
- Religion & Spirituality
- 2302 Private Road 7850 • Hawkins, TX 75765
Be the U in Education
Ruth Hathaway
Saturday, September 20, 2014 from 6:00 PM to 7:30 PM (CDT)
Longview NAACP is hosting an education workshop for parents. Topics include:
It Starts with Us - Parents, School, Community
Help from Home = Success in School (elementary grades)
Help from Home = Success in School (secondary grades)
Be an Advocate for your Child = Success in School (student expectations)
Founded in 1909, the NAACP is the nation's oldest and largest civil rights organization. From the ballot box to the classroom, the thousands of dedicated workers, organizers, leaders and members whomake up the NAACP continue to fight for social justice for all Americans.
Join millions of people on Eventbrite.
In order to purchase these tickets in installments, you'll need an Eventbrite account. Log in or sign up for a free account to continue.


text:
G2D Games
Most Played Games
New Games
Dressup Games
Makeover Games
Girls Games
Celebrity Games
Cool Games
Cooking Games
Baby Games
Fun Games
Game Name
Super Market Shopping Spree
Cool Games
Game Tags
Click Here to Play
Game Details :
The cute little girl it's going to the super market to buy different kind of fruits. For each level she has a different list of fruits to buy and she must complete the puzzle to buy them all. Have fun!
New Games
Winter Streetshot Anim
Barbie Princess Design
Hot 16 Dress Up
Kitty Princess
Peach Princess
Black Laces
Seeing Jewelry
Loose Denim Anime
Bikini Season
Neutral Pastel
Comfy Cozy Anime
Pleated Fashion


text:
Rihanna and Drake: Making it RAIN at Strip Club!
Rekindled quasi-couple Rihanna and Drake made it rain at a Houston strip club Thursday morning, dropping more than $17,000 between them.
Rekindled quasi-couple Rihanna and Drake made it rain at a Houston strip club Thursday morning, dropping more than $17,000 between them.
Rihanna and Drake are back on, according to a report that Chris Brown is not going to be happy with ... though he is in rehab for anger management, conveniently.
The pair met up shortly after her performance in Dallas Monday night, and insiders say that Rihanna, 25, and Drake, 26, took things to the next level.
Drake is on his "Worst Behavior" in his latest music video. So to speak.
The 27-year-old rapper's new effort from his album Nothing Was the Same comes in the form of a 10-minute video that features from his dad, Dennis Graham.
Drake canceled his show the other night in Philadelphia just before it was set to begin, and reportedly the cause was serious fan safety concerns.
Drake has fired Future as the opening act of his "Would You Like A Tour?" tour following a quote from the latter in which he allegedly dissed the former.
When you're the opening act? Not typically a very smart move.
Kendrick Lamar and Drake were the story at the 2013 BET Hip-Hop Awards, which aired Tuesday night, and not only because they won five awards each.
In a two-minute verse, part of a full-length Top Dawg Entertainment Crew freestyle rap "cypher" recorded for the show, the former asserted his dominance again.
There may be some bad blood between Kendrick Lamar and Drake, but both topped the winners list at the 2013 BET Hip-Hop Awards last night.
After scoring 14 nominations, Lamar - who threw shade at Drake once again Tuesday at the Atlanta Civic Center - walked away with five awards.
Kris Jenner allegedly has a plan.
It's already been documented that she wants Khloe Jenner to divorce Lamar Odom - and now sources tell In Touch Weekly that Kris already has a man lined up for her daughter: Drake!


text:
4.5 out of 5
BMW 435i M Sport Convertible review
Volkswagen Cross Coupe GTE concept: The Tiguan from the future (hands-on)16 January 2015
This is VW's latest crossover concept, the Cross Coupe GTE. Shown at the Detroit Auto Show as a proof of concept vision, it hints at the next generation of Volkswagen's crossovers and SUVs. The GTE label – which is the new moniker for high-performance,... >>
Elon Musk's Hyperloop able to do London to Edinburgh run in 30 minutes16 January 2015
Elon Musk, of Tesla and SpaceX fame, has decided to build his Hyperloop concept. The Hyperloop is like a futuristic train that Musk calls "a cross between a Concorde, a railgun and an air hockey table". Essentially it's the Very High Speed Transit System... >>
Audi Q7: Awesome tech meets awkward design (hands-on)15 January 2015
The Audi Q7 was the most important new mainstream production car to be launched at the Detroit Auto Show, joining a growing throng of recently refreshed big SUVs. Given that BMW debuted a new X5 in 2014 (although it looks just like the old one), Volvo... >>
Honda NSX: Ford GT competitor shows off 25 year pedigree (hands-on)15 January 2015
If the Ford GT was the surprise supercar launch at the Detroit Auto Show, then the Honda NSX (here badged as an Acura, for the North American market) was the one we knew we were going to get. After all, Acura has been showing the NSX in concept version... >>
Your next car won't have mirrors, as long as you buy a Maserati (hands-on)13 January 2015
The company that is the underlying tech for most of the cars on the road, QNX, claims that we won't need the wing mirrors or even a rear view mirror in our cars in the future. Demoing a new concept car at CES in Las Vegas, based on a Maserati Quattroporte... >>
Future car tech: Sci-fi cars are closer than you think13 January 2015
Cars have been featured at consumer electronic shows with increasing frequency in recent years, causing some to comment that those shows are becoming car shows. Nothing could be further from the truth. In fact, it's the motor car that's becoming gadgetised.... >>
Seven-seater Audi Q7 only car to come with Bang & Olufsen 3D Advanced Sound System13 January 2015
Bang & Olufsen and Audi have teamed to include the home entertainment company's "most revolutionary collaborative sound system to date". The Audi Q7, unveiled at the North American Motor Show in Detroit, features a Bang & Olufsen 3D Advanced Sound System.... >>
Want to drive the new Ford GT? Forza 6 for Xbox One might be your only option13 January 2015
It must be said that we've been blown away by the surprise announcement at this year's North American Auto Show in Detroit, the Ford GT supercar. It is, quite simply, beautiful. However, our chances of ever driving let alone owning one of the £200,000... >>
VW Golf R Touch hands-on: Forget knobs, VW sees gestures and touchscreen as the future12 January 2015
There are no knobs or dials. Yes that's right, the latest Golf concept from Volkswagen has done away with physical things to touch and turn and instead replaced them with touchscreens and gesture controls. We caught up with the new car at CES in Las Vegas... >>
Chevrolet Bolt electric car concept unveiled with 200-mile range12 January 2015
At the Detroit Auto Show 2015 a new concept car has been unveiled in the Chevrolet Bolt that offers an impressive 200-mile range in a compact car. The Chevvy Bolt, unlike the hybrid Volt already available, uses a completely electric drive train to power... >>


text:
The latest work from Petrolicious focuses on a 1973 Ferrari 365 GTB/4 Daytona that bridges the generations between a father and son as its owners.
With a week of lavish automotive events coming up centered around the Pebble Beach Concours d'Elegance in August, some of the highest profile auto auctions in the world are about to take place. Hearing about Ferrari Testa Rossas and 250 GTOs going for tens of millions of dollars during these events is commonplace, but Gooding & Company is bringing a unique Prancing Horse to sell in California that could be a record-breaker for the company.
Please login using one of the following services:


text:
Are you Phebe S Wulf?Claim your profile
Publications (23)214.73 Total impact
- SourceAvailable from: Max Schlager[Show abstract] [Hide abstract]
ABSTRACT: Cargo transport along microtubules is driven by the collective function of microtubule plus- and minus-end-directed motors (kinesins and dyneins). How the velocity of cargo transport is driven by opposing teams of motors is still poorly understood. Here, we combined inducible recruitment of motors and adaptors to Rab6 secretory vesicles with detailed tracking of vesicle movements to investigate how changes in the transport machinery affect vesicle motility. We find that the velocities of kinesin-based vesicle movements are slower and more homogeneous than those of dynein-based movements. We also find that Bicaudal D (BICD) adaptor proteins can regulate dynein-based vesicle motility. BICD-related protein 1 (BICDR-1) accelerates minus-end-directed vesicle movements and affects Rab6 vesicle distribution. These changes are accompanied by reduced axonal outgrowth in neurons, supporting their physiological importance. Our study suggests that adaptor proteins can modulate the velocity of dynein-based motility and thereby control the distribution of transport carriers.Cell Reports 08/2014; 8(5). DOI:10.1016/j.celrep.2014.07.052 · 7.21 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Bicaudal-D (BICD) belongs to an evolutionary conserved family of dynein adaptor proteins. It was first described in Drosophila as an essential factor in fly oogenesis and embryogenesis. Missense mutations in a human BICD homologue, BICD2, have been linked to a dominant mild early onset form of spinal muscular atrophy. Here we further examine the in vivo function of BICD2 in Bicd2 knockout mice. BICD2-deficient mice develop disrupted laminar organization of cerebral cortex and the cerebellum, pointing to impaired radial neuronal migration. Using astrocyte and granule cell specific inactivation of BICD2, we show that the cerebellar migration defect is entirely dependent upon BICD2 expression in Bergmann glia cells. Proteomics analysis reveals that Bicd2 mutant mice have an altered composition of extracellular matrix proteins produced by glia cells. These findings demonstrate an essential non-cell-autonomous role of BICD2 in neuronal cell migration, which might be connected to cargo trafficking pathways in glia cells.Nature Communications 07/2014; 5:3411. DOI:10.1038/ncomms4411 · 10.74 Impact Factor
Article: Microtubule Minus-End Binding Protein CAMSAP2 Controls Axon Specification and Dendrite Development[Show abstract] [Hide abstract]
ABSTRACT: In neurons, most microtubules are not associated with a central microtubule-organizing center (MTOC), and therefore, both the minus and plus-ends of these noncentrosomal microtubules are found throughout the cell. Microtubule plus-ends are well established as dynamic regulatory sites in numerous processes, but the role of microtubule minus-ends has remained poorly understood. Using live-cell imaging, high-resolution microscopy, and laser-based microsurgery techniques, we show that the CAMSAP/Nezha/Patronin family protein CAMSAP2 specifically localizes to noncentrosomal microtubule minus-ends and is required for proper microtubule organization in neurons. CAMSAP2 stabilizes noncentrosomal microtubules and is required for neuronal polarity, axon specification, and dendritic branch formation in vitro and in vivo. Furthermore, we found that noncentrosomal microtubules in dendrites are largely generated by γ-Tubulin-dependent nucleation. We propose a two-step model in which γ-Tubulin initiates the formation of noncentrosomal microtubules and CAMSAP2 stabilizes the free microtubule minus-ends in order to control neuronal polarity and development.Neuron 06/2014; 82(5):1058-1073. DOI:10.1016/j.neuron.2014.04.019 · 15.98 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Regulation of cargo transport via adaptor molecules is essential for neuronal development. However, the role of PDZ scaffolding proteins as adaptors in neuronal cargo trafficking is still poorly understood. Here, we show by genetic deletion in mice that the multi-PDZ domain scaffolding protein glutamate receptor interacting protein 1 (GRIP1) is required for dendrite development. We identify an interaction between GRIP1 and 14-3-3 proteins that is essential for the function of GRIP1 as an adaptor protein in dendritic cargo transport. Mechanistically, 14-3-3 binds to the kinesin-1 binding region in GRIP1 in a phospho-dependent manner and detaches GRIP1 from the kinesin-1 motor protein complex thereby regulating cargo transport. A single point mutation in the Thr956 of GRIP1 in transgenic mice impairs dendritic development. Together, our results show a regulatory role for GRIP1 during microtubule-based transport and suggest a crucial function for 14-3-3 proteins in controlling kinesin-1 motor attachment during neuronal development.Developmental Cell 02/2014; 28(4):381-93. DOI:10.1016/j.devcel.2014.01.018 · 10.37 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Mechanisms controlling microtubule dynamics at the cell cortex play a crucial role in cell morphogenesis and neuronal development. Here, we identified kinesin-4 KIF21A as an inhibitor of microtubule growth at the cell cortex. In vitro, KIF21A suppresses microtubule growth and inhibits catastrophes. In cells, KIF21A restricts microtubule growth and participates in organizing microtubule arrays at the cell edge. KIF21A is recruited to the cortex by KANK1, which coclusters with liprin-α1/β1 and the components of the LL5β-containing cortical microtubule attachment complexes. Mutations in KIF21A have been linked to congenital fibrosis of the extraocular muscles type 1 (CFEOM1), a dominant disorder associated with neurodevelopmental defects. CFEOM1-associated mutations relieve autoinhibition of the KIF21A motor, and this results in enhanced KIF21A accumulation in axonal growth cones, aberrant axon morphology, and reduced responsiveness to inhibitory cues. Our study provides mechanistic insight into cortical microtubule regulation and suggests that altered microtubule dynamics contribute to CFEOM1 pathogenesis.Developmental Cell 10/2013; DOI:10.1016/j.devcel.2013.09.010 · 10.37 Impact Factor
Article: Myosin-V Opposes Microtubule-Based Cargo Transport and Drives Directional Motility on Cortical Actin.[Show abstract] [Hide abstract]
ABSTRACT: Intracellular transport is driven by motor proteins that either use microtubules or actin filaments as their tracks [1], but the interplay between these transport pathways is poorly understood [2-4]. Whereas many microtubule-based motors are known to drive long-range transport, several actin-based motors have been proposed to function predominantly in cargo tethering [4-6]. How these opposing activities are integrated on cargoes that contain both types of motors is unknown. Here we use inducible intracellular transport assays to show that acute recruitment of myosin-V to kinesin-propelled cargo reduces their motility near the cell periphery and enhances their localization at the actin-rich cell cortex. Myosin-V arrests rapid microtubule-based transport without the need for regulated auto- or other inhibition of kinesin motors. In addition, myosin-V, despite being an ineffective long-range transporter, can drive slow, medium-range (1-5 μm), point-to-point transport in cortical cell regions. Altogether, these data support a model in which myosin-V establishes local cortical delivery of kinesin-bound cargos through a combination of tethering and active transport.Current biology: CB 04/2013; DOI:10.1016/j.cub.2013.03.068 · 9.92 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: In neurons, the distinct molecular composition of axons and dendrites is established through polarized targeting mechanisms, but it is currently unclear how nonpolarized cargoes, such as mitochondria, become uniformly distributed over these specialized neuronal compartments. Here, we show that TRAK family adaptor proteins, TRAK1 and TRAK2, which link mitochondria to microtubule-based motors, are required for axonal and dendritic mitochondrial motility and utilize different transport machineries to steer mitochondria into axons and dendrites. TRAK1 binds to both kinesin-1 and dynein/dynactin, is prominently localized in axons, and is needed for normal axon outgrowth, whereas TRAK2 predominantly interacts with dynein/dynactin, is more abundantly present in dendrites, and is required for dendritic development. These functional differences follow from their distinct conformations: TRAK2 preferentially adopts a head-to-tail interaction, which interferes with kinesin-1 binding and axonal transport. Our study demonstrates how the molecular interplay between bidirectional adaptor proteins and distinct microtubule-based motors drives polarized mitochondrial transport.Neuron 02/2013; 77(3):485-502. DOI:10.1016/j.neuron.2012.11.027 · 15.98 Impact Factor
Article: Differential expression of liprin-α family proteins in the brain suggests functional diversification[Show abstract] [Hide abstract]
ABSTRACT: Liprin-α proteins are major protein constituents of synapses and are important for the organization of synaptic vesicles and neurotransmitter receptors on their respective sides of the synapse. Although it is becoming apparent that the single liprin-α gene in invertebrates is essential for synapse function, it is not known to what extent the four different liprin-α homologs (liprin-α1-4) in mammals are involved at synapses. We have designed specific antibodies against each of the four liprin-α proteins and investigated their regional and cellular distribution in the brain. Here we show that all four liprin-α proteins are present throughout the mature brain but have different regional distributions, which is highlighted by their differential localization in olfactory bulb, hippocampus, and cerebellar cortex. Double-immunofluorescence staining indicates that different liprin-α proteins are enriched in different synaptic populations but are also present at nonsynaptic sites. In particular, liprin-α2 is preferentially associated with hippocampal mossy fiber endings in the CA3, whereas synapses in the molecular layers of the CA1 and dentate gyrus double-labeled for liprin-α3. The localization of liprin-α2 and liprin-α3 with excitatory synapses was confirmed in cultured primary hippocampal neurons. Liprin-α4, which poorly co-distributed with presynaptic markers in hippocampus, instead strongly co-localized with VGLUT1 in the cerebellar molecular layer, suggesting its presence in parallel fiber-Purkinje cell synapses. Finally, staining of cultured glial cells indicated that liprin-α1 and liprin-α3 are also associated with astrocytes. We conclude that liprin-α family proteins might perform independent and specialized synaptic and nonsynaptic functions in different regions of the brain.The Journal of Comparative Neurology 10/2011; 519(15):3040-60. DOI:10.1002/cne.22665 · 3.51 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Dynamic microtubules are important to maintain neuronal morphology and function, but whether neuronal activity affects the organization of dynamic microtubules is unknown. Here, we show that a protocol to induce NMDA-dependent long-term depression (LTD) rapidly attenuates microtubule dynamics in primary rat hippocampal neurons, removing the microtubule-binding protein EB3 from the growing microtubule plus-ends in dendrites. This effect requires the entry of calcium and is mediated by activation of NR2B-containing NMDA-type glutamate receptor. The rapid NMDA effect is followed by a second, more prolonged response, during which EB3 accumulates along MAP2-positive microtubule bundles in the dendritic shaft. MAP2 is both required and sufficient for this activity-dependent redistribution of EB3. Importantly, NMDA receptor activation suppresses microtubule entry in dendritic spines, whereas overexpression of EB3-GFP prevents NMDA-induced spine shrinkage. These results suggest that short-lasting and long-lasting changes in dendritic microtubule dynamics are important determinants for NMDA-induced LTD.The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 06/2011; 31(22):8194-209. DOI:10.1523/JNEUROSCI.6215-10.2011 · 6.75 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Dendritic arbors are compartments of neurons dedicated to receiving synaptic inputs. Their shape is an outcome of both the intrinsic genetic program and environmental signals. The microtubules and actin cytoskeleton are both crucial for proper dendritic morphology, but how they interact is unclear. The present study demonstrates that microtubule plus-end tracking protein CLIP-170 and actin-binding protein IQGAP1 regulate dendrite morphology of rat neurons by coordinating the interaction between microtubules and the actin cytoskeleton. Moreover, we show that mTOR kinase interacts with CLIP-170 and is needed for efficient formation of a protein complex containing CLIP-170 and IQGAP1. Dynamic microtubules, CLIP-170, and IQGAP1 are required for proper dendritic arbor morphology and PI3K-mTOR-induced increase in dendritic arbor complexity. Moreover, CLIP-170 and IQGAP1 knockdown modulates dendritic arbor growth via regulation of the actin cytoskeleton. We postulate that mTOR controls dendritic arbor morphology by enhancing cross talk between dynamic microtubules and actin through CLIP-170 and IQGAP1.The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 03/2011; 31(12):4555-68. DOI:10.1523/JNEUROSCI.6582-10.2011 · 6.75 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Although purified cytoskeletal motor proteins have been studied extensively with the use of in vitro approaches, a generic approach to selectively probe actin and microtubule-based motor protein activity inside living cells is lacking. To examine specific motor activity inside living cells, we utilized the FKBP-rapalog-FRB heterodimerization system to develop an in vivo peroxisomal trafficking assay that allows inducible recruitment of exogenous and endogenous kinesin, dynein, and myosin motors to drive specific cargo transport. We demonstrate that cargo rapidly redistributes with distinct dynamics for each respective motor, and that combined (antagonistic) actions of more complex motor combinations can also be probed. Of importance, robust cargo redistribution is readily achieved by one type of motor protein and does not require the presence of opposite-polarity motors. Simultaneous live-cell imaging of microtubules and kinesin or dynein-propelled peroxisomes, combined with high-resolution particle tracking, revealed that peroxisomes frequently pause at microtubule intersections. Titration and washout experiments furthermore revealed that motor recruitment by rapalog-induced heterodimerization is dose-dependent but irreversible. Our assay directly demonstrates that robust cargo motility does not require the presence of opposite-polarity motors, and can therefore be used to characterize the motile properties of specific types of motor proteins.Biophysical Journal 10/2010; 99(7):2143-52. DOI:10.1016/j.bpj.2010.07.055 · 3.83 Impact Factor
Article: Correction: Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes[Show abstract] [Hide abstract]
ABSTRACT: [This corrects the article on p. e1000283 in vol. 8.].PLoS Biology 09/2010; 8(9). DOI:10.1371/annotation/b17dfb99-8809-4c5a-86c2-c2a0f7ca7f5e · 11.77 Impact Factor
Article: Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis[Show abstract] [Hide abstract]
ABSTRACT: Membrane and secretory trafficking are essential for proper neuronal development. However, the molecular mechanisms that organize secretory trafficking are poorly understood. Here, we identify Bicaudal-D-related protein 1 (BICDR-1) as an effector of the small GTPase Rab6 and key component of the molecular machinery that controls secretory vesicle transport in developing neurons. BICDR-1 interacts with kinesin motor Kif1C, the dynein/dynactin retrograde motor complex, regulates the pericentrosomal localization of Rab6-positive secretory vesicles and is required for neural development in zebrafish. BICDR-1 expression is high during early neuronal development and strongly declines during neurite outgrowth. In young neurons, BICDR-1 accumulates Rab6 secretory vesicles around the centrosome, restricts anterograde secretory transport and inhibits neuritogenesis. Later during development, BICDR-1 expression is strongly reduced, which permits anterograde secretory transport required for neurite outgrowth. These results indicate an important role for BICDR-1 as temporal regulator of secretory trafficking during the early phase of neuronal differentiation.The EMBO Journal 04/2010; 29(10):1637-51. DOI:10.1038/emboj.2010.51 · 10.75 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: To establish and maintain their polarized morphology, neurons employ active transport driven by molecular motors to sort cargo between axons and dendrites. However, the basic traffic rules governing polarized transport on neuronal microtubule arrays are unclear. Here we show that the microtubule minus-end-directed motor dynein is required for the polarized targeting of dendrite-specific cargo, such as AMPA receptors. To directly examine how dynein motors contribute to polarized dendritic transport, we established a trafficking assay in hippocampal neurons to selectively probe specific motor protein activity. This revealed that, unlike kinesins, dynein motors drive cargo selectively into dendrites, governed by their mixed microtubule array. Moreover, axon-specific cargos, such as presynaptic vesicle protein synaptophysin, are redirected to dendrites by coupling to dynein motors. Quantitative modeling demonstrated that bidirectional dynein-driven transport on mixed microtubules provides an efficient mechanism to establish a stable density of continuously renewing vesicles in dendrites. These results demonstrate a powerful approach to study specific motor protein activity inside living cells and imply a key role for dynein in dendritic transport. We propose that dynein establishes the initial sorting of dendritic cargo and additional motor proteins assist in subsequent delivery.Current biology: CB 02/2010; 20(4):290-9. DOI:10.1016/j.cub.2009.12.052 · 9.92 Impact Factor
Article: Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes.[Show abstract] [Hide abstract]
ABSTRACT: The endosomal pathway in neuronal dendrites is essential for membrane receptor trafficking and proper synaptic function and plasticity. However, the molecular mechanisms that organize specific endocytic trafficking routes are poorly understood. Here, we identify GRIP-associated protein-1 (GRASP-1) as a neuron-specific effector of Rab4 and key component of the molecular machinery that coordinates recycling endosome maturation in dendrites. We show that GRASP-1 is necessary for AMPA receptor recycling, maintenance of spine morphology, and synaptic plasticity. At the molecular level, GRASP-1 segregates Rab4 from EEA1/Neep21/Rab5-positive early endosomal membranes and coordinates the coupling to Rab11-labelled recycling endosomes by interacting with the endosomal SNARE syntaxin 13. We propose that GRASP-1 connects early and late recycling endosomal compartments by forming a molecular bridge between Rab-specific membrane domains and the endosomal SNARE machinery. The data uncover a new mechanism to achieve specificity and directionality in neuronal membrane receptor trafficking.PLoS Biology 01/2010; 8(1):e1000283. DOI:10.1371/journal.pbio.1000283 · 11.77 Impact Factor
Article: Neuron specific Rab4 effector GRASP1 coordinates membrane specialization and maturation of recycling endosomes[Show abstract] [Hide abstract]
ABSTRACT: The endosomal pathway in neuronal dendrites is essential for membrane receptor trafficking and proper synaptic function and plasticity. However, the molecular mechanisms that organize specific endocytic trafficking routes are poorly understood. Here, we identify GRIP-associated protein-1 (GRASP-1) as a neuron-specific effector of Rab4 and key component of the molecular machinery that coordinates recycling endosome maturation in dendrites. We show that GRASP-1 is necessary for AMPA receptor recycling, maintenance of spine morphology, and synaptic plasticity. At the molecular level, GRASP-1 segregates Rab4 from EEA1/Neep21/Rab5-positive early endosomal membranes and coordinates the coupling to Rab11-labelled recycling endosomes by interacting with the endosomal SNARE syntaxin 13. We propose that GRASP-1 connects early and late recycling endosomal compartments by forming a molecular bridge between Rab-specific membrane domains and the endosomal SNARE machinery. The data uncover a new mechanism to achieve specificity and directionality in neuronal membrane receptor trafficking.
- [Show abstract] [Hide abstract]
ABSTRACT: Dendritic spines are the major sites of excitatory synaptic input, and their morphological changes have been linked to learning and memory processes. Here, we report that growing microtubule plus ends decorated by the microtubule tip-tracking protein EB3 enter spines and can modulate spine morphology. We describe p140Cap/SNIP, a regulator of Src tyrosine kinase, as an EB3 interacting partner that is predominantly localized to spines and enriched in the postsynaptic density. Inhibition of microtubule dynamics, or knockdown of either EB3 or p140Cap, modulates spine shape via regulation of the actin cytoskeleton. Fluorescence recovery after photobleaching revealed that EB3-binding is required for p140Cap accumulation within spines. In addition, we found that p140Cap interacts with Src substrate and F-actin-binding protein cortactin. We propose that EB3-labeled growing microtubule ends regulate the localization of p140Cap, control cortactin function, and modulate actin dynamics within dendritic spines, thus linking dynamic microtubules to spine changes and synaptic plasticity.Neuron 02/2009; 61(1):85-100. DOI:10.1016/j.neuron.2008.11.013 · 15.98 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Exocytic events are tightly regulated cellular processes in which rab GTPases and their interacting proteins perform an important function. We set out to identify new binding partners of rab3, which mediates regulated secretion events in specialized cells. We discovered Zwint-1 as a rab3 specific binding protein that bound preferentially to rab3c. The interaction depends on a critical residue in rab3c that determines the binding efficiency of Zwint-1, which is immaterial for interaction with rabphilin3a. Rab3c and Zwint-1 are expressed highly in brain and colocalized extensively in primary hippocampal neurons. We also found that SNAP25 bound to the same region in Zwint-1 as rab3c, suggesting a new role for the kinetochore protein Zwint-1 in presynaptic events that are regulated by rab3 and SNAP25.FEBS Letters 08/2008; 582(19):2838-42. DOI:10.1016/j.febslet.2008.07.012 · 3.34 Impact Factor
Article: A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice[Show abstract] [Hide abstract]
ABSTRACT: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition characterized by progressive motor neuron degeneration and muscle paralysis. Genetic evidence from man and mouse has indicated that mutations in the dynein/dynactin motor complex are correlated with motor neuron degeneration. In this study, we have generated transgenic mice with neuron-specific expression of Bicaudal D2 N-terminus (BICD2-N) to chronically impair dynein/dynactin function. Motor neurons expressing BICD2-N showed accumulation of dynein and dynactin in the cell body, Golgi fragmentation and several signs of impaired retrograde trafficking: the appearance of giant neurofilament swellings in the proximal axon, reduced retrograde labelling by tracer injected in the muscle and delayed expression of the injury transcription factor ATF3 after axon transection. Despite these abnormalities, BICD2-N mice did not develop signs of motor neuron degeneration and motor abnormalities. Interestingly, the BICD2-N transgene increased lifespan in 'low copy' SOD1-G93A ALS transgenic mice. Our findings indicate that impaired dynein/dynactin function can explain several pathological features observed in ALS patients, but may be beneficial in some forms of ALS.Human Molecular Genetics 07/2008; 17(18):2849-62. DOI:10.1093/hmg/ddn182 · 6.68 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Constitutive exocytosis delivers newly synthesized proteins, lipids, and other molecules from the Golgi apparatus to the cell surface. This process is mediated by vesicles, which bud off the trans-Golgi network, move along cytoskeletal filaments, and fuse with the plasma membrane. Here, we show that the small GTPase Rab6 marks exocytotic vesicles and, together with the microtubule plus-end-directed motor kinesin-1, stimulates their processive microtubule-based transport to the cell periphery. Furthermore, Rab6 directs targeting of secretory vesicles to plasma-membrane sites enriched in the cortical protein ELKS, a known Rab6 binding partner. Our data demonstrate that although Rab6 is not essential for secretion, it controls the organization of exocytosis within the cellular space.Developmental Cell 09/2007; 13(2):305-14. DOI:10.1016/j.devcel.2007.06.010 · 10.37 Impact Factor
Top Journals
Universiteit Utrecht
Utrecht, Utrecht, Netherlands
- Department of Cell Biology
Erasmus MC
Rotterdam, South Holland, Netherlands
- Department of Neuroscience
Erasmus Universiteit RotterdamRotterdam, South Holland, Netherlands
University of MünsterMuenster, North Rhine-Westphalia, Germany


text:
On your mobile? Click here for free downloads.
Full Version
Like the push tile puzzle to reveal the image. Only the image is an animation.
Uploaded: September 28, 2009
168,896 downloads
Full Version
Think you're tough - trying beating the worlds toughest in a fight of the fittest.
Uploaded: September 28, 2009
780,481 downloads
Full Version
Enjoy the excitement of a trivia game show from your mobile phone! Earn points for accuracy and reliability and set high scores. This package has > 100 questions in the category 'Games'.
Uploaded: January 8, 2010
257,158 downloads
Free Trial/Demo
Play the classic game of Tic-Tac-Toe against your phone! Four difficulty levels: easy, medium, hard and very hard. Players can either play against the machine, or with a friend.
Uploaded: September 28, 2009
100,459 downloads
Free Ad-supported
Flogo is a strategy game with nice graphics and sounds. Play against an AI in 20 different levels.
Uploaded: October 26, 2009
339,208 downloads
Full Version
A pick 3 or more blocks of the same color type game. The screen is filling up with blocks, you must be fast to remove same colored blocks and bring them crashing down.
Uploaded: September 28, 2009
115,542 downloads
Free Ad-supported
IQ Valentine - sweet mobile phone application that helps you show your lover that you care!
Uploaded: April 5, 2010
111,366 downloads
Full Version
Age of Heroes Online is a mobile multiuser Java game following the traditions of such iconic projects as Heroes of Might and Magic and Kings Bounty. Player controls a hero who commands the whole army consisting of different creatures. All creatures have their own characteristics and skills, they can ...
Uploaded: October 6, 2009
179,237 downloads
Full Version
Future Force returns with more baddies, more ships, more upgrades, more levels and more more! Fight smart enemies that don`t follow patterns, upgrade your ship, fight alongside allies and rise through the ranks! * Over 45 different enemies. * Enemies come from more than one direction. * Fig ...
Uploaded: September 28, 2009
291,076 downloads
Full Version
Jacks or Better poker is a free fun play video poker game. Beat our video poker machine and get into our hall of fame at wapfrog.com (touch included)
Uploaded: April 19, 2011
326,231 downloads
Find software compatible with your RIM BlackBerry 9700
Receive email alerts for new RIM BlackBerry 9700 games and apps!


text:
- About
- Exhibitors
- Media
- Events
- FAQs
- Contact Us
Tools & Equipment
HushMat Introduces Large Sheet & Mega Bulk Kits for USA & Canada
Olathe, Kansas November 4, 2013 HushMat® – HushMat launches larger sheet sizes to automotive aftermarket.
HushMat has introduced new manufacturing technology to produce the #1 Rated Sound Deadening & Thermal Insulating Ultra material is new/larger 32" x 18" and 24" x 48" sheet sizes. HushMat, the fastest growing automotive sound deadening and thermal insulating materials company, leads the worldwide automotive aftermarket in this category.
"This is another example of HushMat dominating the category by technology leadership, mastering the manufacturing challenge of large dimension sheet extrusion. Customers asked for it and HushMat delivers again.", stated Tim McCarthy, Founder of HushMat. The larger sheet sizes will offer installers, reduced installation time and lower overall economics with greater packaging density to lower overall delivered cost. This makes HushMat even more attractive for all customers", McCarthy added.
HushMat Supports Iowa Couple's Midwest Pride in Your Ride Cancer Fund
HushMat Supports Iowa Couple's Midwest Pride in Your Ride Cancer Fund
Olathe, Kansas November 4, 2013 HushMat® – HushMat sponsors Eldon & Barb Jaeger's 2000 Peterbilt 379 and fund raising for Cancer Society in daughter Brenda's name.
HushMat, the market leader in automotive sound deadening & thermal insulation materials sponsored the fabulous 2000 Peterbilt 379 Truck customized with too many products to list here. Eldon & Barb Jaeger have driven around the country since early 2013 promoting this truck raising funds in support of finding cure for all cancer. Eldon & Barb's daughter Brenda battled cancer over 14 years before losing her battle at the age of 32. Eldon & Barb have donated this fully customized 2000 Peterbilt. They are a tremendous inspiration to all.
Huf TPMS "IntelliSens" now supported by Bartec tools
Velbert/Germany, October 2013 Huf, one of the leading German tire pressure monitoring systems (TPMS) manufacturer has agreed with Bartec Ltd. to have the new "IntelliSens" universal sensors operated by their diagnosis tools. The leading TPMS tool supplier in the US has updated its database to also service the requirements of Huf´s "IntelliSens".
Huf to provide services and TPMS training
Velbert/Germany October 2013 Huf, a tire pressure monitoring system (TPMS) supplier offers a range of services to tire and repair shops in the aftermarket, in order to support them when training their personnel.
"We want to help our partners in the aftermarket to sell and use our products in the best way possible", John Stratton, Aftermarket Sales Manager for Huf North America explains.
Huf offers a new TPMS tool
Velbert/Germany, October 2013 Huf, a German tire pressure monitoring system (TPMS) producer presents a new tool for tire and repair shops at the 2013 SEMA Show. The tool VT56 – powered by ATEQ – is the first tool which is operated by a sensational new hi resolution display using icons. Huf supplies TPMS to tire and repair shops either as an original equipment (OE) sensor or as "IntelliSens" universal sensor, which are installed in conjunction with the new tool. "It is our philosophy to look for easy and fast solutions for our partners in the market. That is why we developed this new tool, which is simple and comfortable to use, because you are guided through the menu using icons. It is easier to navigate and read. "The new tool saves time and money", says John Stratton Aftermarket Sales Manager of Huf North America.
Tire pressure monitoring systems - Huf´s Revolutionary "IntelliSens" Universal Sensor
Germany, October 2013 In accordance with the needs of tire and repair shops in the aftermarket Huf has developed a revolutionary concept for tire pressure monitoring systems (TPMS): The "IntelliSens" universal sensor. Car manufacturers design TPMS according to their individual concepts which leads to a large range of variants leaving tire and repair shops with the problem of stocking numerous part numbers. Huf offers the solution by developing a universal sensor which – in only very few variants – covers almost all car models and helps to keep stocks low.
The NEW Inductor® Pro-Max IQ™ has been engineered with greater intellect that enables programming capabilities, digital readout and enhanced with timed operation capabilities and precise power settings. The multi-function, easy-to-read digital display sets operation time; displays time remaining and act as a timer, and displays power output levels. The linear knob adjusts settings on the display, with push to select mode. These new digital features add greater power control to take advantage of induction heating for curing of bonding compounds and other materials.
Induction Innovations has re-engineered their flameless torch into the NEW MINI-DUCTOR® 2 GO! Designed to be completely portable – works with a standard 12-volt battery pack, even runs off a car battery! Leave the generator behind and can take the MINI-DUCTOR 2 GO anywhere you need it – out in the field, across the lot or even out in space!
The MINI-DUCTOR® 2 GO heats ferrous metals without the danger of an open flame using invisible heat and turns a ¾" nut red hot in seconds. HUGE variety of heating applications for operating safer than a torch! Easily release seized nuts/bolts from corrosion or thread lock compounds. Remove/release; steering/suspension components, fuel tank straps, inline connectors, zirk fittings, manifold bolts, truck bed bolts, seat belt bolts, u-bolts, tie rod sleeves/ends, soft hail dents, metal fabrication, soldering, and even heat treating. Easily remove heavy undercoating's applied over hardware.
• 12v Battery Operated
Induction Innovations has developed a NEW PDR attachment to complement its line of high performance induction heating tools. Unlike traditional PDR, the Invisible Heat® method is the cleanest and fastest way for fixing hail dents, door dings and other minor soft dents. There is no need to meticulously massage out from the backside of vehicle panels, especially in hard-to-reach areas, or areas difficult to get behind. Induction heating is the highest tech method for removing soft dents, the result is a clean dent repair in a fraction of the time compared to a conventional PDR tool.
The ergonomically designed INDUCTOR® PDR Baton is molded in high temp / impact resistant epoxy polymers for additional durability and versatility longevity. Tapered body and beveled edges on this attachment allows for balanced grip. The PDR Baton works in conjunction with either the INDUCTOR PRO-MAX or the INDUCTOR MAX power supplies
• 1 Year Warranty
The MINI-DUCTOR® II + is the #1 professionals choice hand held flameless torch! Induction Innovations engineered new technology and redesigned their 230V international version of the Mini-Ductor II! The MINI-DUCTOR II + integrates these new advances in technology for increased energy efficiency and ease of use. Leverage the power of technology with invisible heat to quickly release corroded or frozen hardware and other metallic components from corrosion and thread lock compounds. All WITHOUT the collateral damage associated with torches! Heats nuts red hot in seconds!
• NEW Cool-Touch Handle
• NEW technology inside – power where and when you need it
• Increased energy efficiency
• In-line design proven most effective in reaching difficult spots.
• Ergonomic balanced design reduces user fatigue
• Non-slip grenade handle
• Military grade virgin plastic for durability
• LED work light
• 1 year warranty
• NEW custom heavy duty blow-molded case with storage