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How did three Danes end up being tortured in Lebanon?
The human cost of the Greek financial crisis
23 Nov 2013 10:12 GMT | Politics, Human Rights, US & Canada, United States, Vietnam
Crowds have gathered in the US city of Dallas to observe a moment of silence to mark the 50th anniversary of the assassination of President John F Kennedy in the city's Dealey Plaza.
The moment of silence began on Friday at 12:30 pm (1830 GMT), the moment on November 22, 1963 when the fatal shots were fired at Kennedy's motorcade from the Texas School Book Depository by Lee Harvey Oswald.
The young leader's brutal televised death, a dark turning point even in an era gripped by the Cold War nuclear stand-off and bloodshed in the jungles of Vietnam, shocked a global audience of millions.
Five decades on the wound is still raw, with many still obsessed by the conspiracy theories surrounding his death, and others gripped by regret for the America they imagine might have been.
Across the nation, at ceremonies large and small, many took comfort in reflecting upon the words of a charismatic man whose soaring rhetoric and call to service continues to inspire.
"Today, we honour his memory and celebrate his enduring imprint on American history," President Barack Obama declared.Remembered overseas
Across the Atlantic too, Kennedy was remembered. A wreath-laying ceremony was planned in the Berlin neighborhood where Kennedy gave his famed Cold War-era "Ich bin ein Berliner" speech to a rapturous crowd.
At Kennedy's tomb in Arlington Cemetery outside Washington, two kilted pipers from the Black Watch of the British army repeated a tribute their regiment had performed at his funeral 50 years ago.
Today and in the decades to come, let us carry his legacy forward.
US President Barack Obama
In a proclamation ordering flags be lowered at government buildings and even private homes, Obama recalled Kennedy's leadership in the Cuban missile crisis, his speech in Berlin and his drive to advance the rights of African Americans and women.
"Today and in the decades to come, let us carry his legacy forward," Obama wrote on Thursday.
"Let us face today's tests by beckoning the spirit he embodied - that fearless, resilient, uniquely American character that has always driven our Nation to defy the odds, write our own destiny, and make the world anew."
In Arlington, a steady stream of mourners visited Kennedy's grave, including his last remaining sibling Jean Kennedy Smith.
"It was a major shock to the world," said Tom Brown, 71, a retired civil servant. "Here we are, 50 years later, and we still remember. We still want to acknowledge him and his presidency."
Student Caitlin Coffey, 22, said she came down from Toronto specifically for the occasion.
"It's just remarkable to think that one person, one family, was able to make such a global difference," she told the AFP news agency.
Kennedy's voice still echoes through history to so many Americans.
"Ask not what your country can do for you; ask what you can do for your country," he urged Americans at his inaugural address on January 20, 1961.
Source: Al Jazeera and agencies
Photographer releases intimate images showing John F Kennedy, his family and friends.
US & Canada, United States
City that 'killed Kennedy' seeks to redefine itself 50 years since US president's assassination.
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A deep-seated cultural preference for boys is skewing India's sex ratio and making slaves of women.
Human Rights, Asia, India
Migrants complain of being sent to squalid shelters, as France unveils plan to reduce asylum processing times.
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Changing climate, unpredictable rains dry out the land, threaten the pastoral way of life in Somaliland.
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Minister makes announcement on personal blog as European creditors scramble to respond to "No" vote in debt referendum.
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Kurdish Peshmerga forces reclaim village hours after ISIL fighters seized it during clashes near oil-rich Iraqi city.
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After decades of tension and hostility between the two nations, has change finally come to US-Cuba relations?


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High Cascade presents The Summer Movie: Part 4
It's the first week of May and that's when it really sets in. Local lifts are closed and your snowboard is starting to collect dust in the corner. You wakeRead More
It's the first week of May and that's when it really sets in. Local lifts are closed and your snowboard is starting to collect dust in the corner. You wakeRead More
A vacation for everyone. FOR IMMEDIATE RELEASE Mt. Hood, Oregon (March 24th, 2015) – High Cascade Snowboard Camp is pleased to announce the addition of Family Camp to its lineupRead More
March 25, 2014 (MT. HOOD, OR) – Spend the summer snowboarding with the world's first-ever Olympic Slopestyle Gold medalists Sage Kotsenburg and Jamie Anderson and three-time Olympic Halfpipe medalist Kelly Clark. HighRead More
Come ride with your favorite pro snowboarders this summer at High Cascade Snowboard Camp.Read More
The same life-altering 8-day experience with prices and payment options you'll love.Read More
Flatground 'boarding at Mount Hood.Read More
Marko Grilc and Danny Davis head to Mt. Hood, Oregon.Read More
SNOWBOARDER Video Magazine Episode 4 closes out the summer at Mt. Hood.Read More
Cobra Dogs has added two old members to their new weenie team. See what we did there? We used member and weenie in the same sentence. Russel Winfield and Terje and The Palm. OK. Palmer Snowfield. God it would have been so sick if Shaun Palmer was in this edit. Nonetheless, Terje's chicken wing mctwists are insane and Russell might be riding the pipe better today than he did twenty years ago. Grasser reverts! We'd say "Fuck Yeah" but better not incase Terje's kids read this.Read More
Chris Beresford will be at High Cascade Snowboard Camp for Session 2 (June 25 – July 2) and we want to give you his gear. Here's how it works: BeRead More

subset: commoncrawl


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SUMMARY: Do you make the all-too-common mistake of relying on current customer feedback to decide how to acquire new customers? Last year John Deere (radically) revamped its market research tactics for the mass consumer marketplace, including:
- Hiring a new in-house team
- Changing focus from product-centric to consumer-centric
- Mixing qualitative and quantitative data
The results were fabulous. Deere achieved a 62% market share gain in the consumer mower arena.
Get the latest research on email, lead gen, and social media along with MarketingSherpa updates and promotions.
Email Marketing: How the Kentucky Derby engages customers with relevant email
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Marketing Analytics by Mike Grigsby


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A brisk nine with Tiger before he gives the most heavily-anticipated quasi-press conference in history. All three networks are cutting in live to show this, the first time this has been done for an athlete since Brett Szabo's retirement announcement in July of 1997.
1. Will Tiger give us the Kobe/A-Rod press conference fake cry, or will he actually go The Full Vermeil and break down?
Kobe's was the best, wasn't it? He was like the bizarro Meryl Streep. His 2009 playoff face was really closely related to his press conference face, actually. Not quite brothers, more like cousins. Like Dora and Diego (what, you don't watch that every morning?)
I predict no tears from Tiger, but you will get the "step back, put the hand on the mouth and take a deep breath" move at least once. Guaranteed. I bet that tested really well with the fifty focus groups they ran this statement by over the past few days. I also predict that during the reading of the statement he will refrain from sexting almost completely. And if he manages to pull that off it will be huge. Quickly. Bye.
2. Is there any chance that Elin shows up?
About none, I'd guess. Even when things were (seemingly) swell you almost never saw her. I still don't think I've ever heard her speak. And I'm thinking she's probably not at the point where she wants to throw him a lifeboat. So no. Frankly, I'd be less surprised if he showed up with all 19 of his harem and faithfully reenacted Act II of "A Chorus Line."
(By the way, someone told me that Elin was wearing just a bra and panties when she went out and bashed Tiger's car in. This person would have no way of knowing that, but it remains the sexiest image I can possibly think of and I stand by it as 100 percent true. So much so that I told another person the same story except I added that she was slightly drunk and wearing heels. There is no point to this, except that I am emotionally vacant.)
3. Why now?
Good question. Tim Finchem (PGA Tour commish) hinted that he may be heading back into rehab and this was the only day that fit into his schedule. Seems strange to me, but I guess that it's possible. I don't know if Dr. Drew is OK with all this, but I guess we'll have to wait for the season premiere. I understand that Tiger is rooming with Jonny Fairplay and Bernie Kopell, so that should be good television.
4. Hey, how is it possible that no one but Tiger knew that he was messing around? Really, no one else?
Yeah, I could buy him keeping maybe a half dozen or quiet, but 19? I don't know, everyone from Mark O'Meara (the Charles Oakley to his Michael Jordan, to give you an idea of just how white the PGA Tour is) to Steve Williams to Charles Barkley to each of the 19 girls claim to have known nothing. Impossible, of course. And this is arguably the most famous person in the world. I'm shocked that one PGA player hasn't come forward and basically said "come on, we all knew this was going on." I mean, the story was going to break a couple of years ago before Tiger's people made a deal to kill it (The Enquirer had it cold, but it was squashed when Tiger agreed to do a cover shoot and interview with Men's Fitness, owned by the same parent company as the Enquirer.) So it was out there.
5. Will there be any surprises in the statement?
Besides his preference for the new "We Are the World" over the original? No, you are going to get exactly what you're expecting. He'll apologize, admit his mistakes, acknowledge that he's getting help and that'll be it. I have to work to do to keep my family, please respect our privacy as we do so, all that stuff. We know the whole album by now with these kinds of deals, right? Some people are, I think, expecting that he'll announce his return date to the PGA Tour but I don't think that'll happen. Not that kind of event. He'll be in and out of there in two minutes, the old "Perkins Special", as he might call it.
(The irony of all this, of course, is that we all are waiting to hear what Tiger has to say when in the 15 years or so we have known him he has never said a single interesting thing. There is no worse interview in sports. Straight out of the Jordan/Derek Jeter "give them nothing" school. Jonathan Papelbon has had more quality sound bites in any single interview than Woods has had in his career. Any chance Papelbon can make the 300-mile drive from Fort Myers to Ponte Vedra and act as Tiger's spokesman?)
6. Why no questions from the press?
Come on, we know why. Nobody is more protected (all irony aside.) And I get that they don't want a TMZ fest in there. But I'd let a couple of respected veteran golf writers in the room to at least ask a few softballs. The people advising Tiger (and Tiger himself) have screwed this whole post-car crash era up from soup to nuts. Have they done anything right? This "press conference" is already been judged a failure for Tiger before it even happens. That's not an easy feat to pull off.
Now what he should do is take a page from A-Rod and McGwire and pick a friendly face (a Jim Nantz or Kelly Tilghman or even Oprah) and sit down for an hour and take his medicine. Try and put the ball back in the fairway, if you'll allow a pathetic attempt to tie it all in. And I suspect that will happen at some point in the next couple of months, assuming he cares about trying to restore his image.
7. If the Stuttering John of, say, 1996 was allowed into the room what would be the one question he would shout at Tiger?
One of these three, I would imagine.
"Tiger, Tiger. If you really are a sex addict how did you resist grabbing Phil Mickelson's breasts for all those years?"
"Are you wearing a condom right now?"
"Do you think Evan Bayh deciding not to seek reelection for his Senate seat in Indiana is a death blow to the health care bill?"
8. With the addition of Nate Robinson is this officially the most unlikable Celtics team of your lifetime?
Hey, how did this sneak in here? Can Danny bring in more team chemistry killers? How about trading a couple of first-rounders for Carl Everett and Roger Dorn?
As long as you really like guys that don't care about winning or losing as long as they get their shots then Nate is the guy for you. And who has played in more big games? At least Eddie House hasn't had about 50 big playoff moments in two years or anything. Out in the second round. Book it. But at least Rasheed Wallace will be back next year.
9. Back to Tiger. Why, again, should we care about this statement/press conference/whatever it is?
You shouldn't. It couldn't be any less our business. Any of it. And that's what Tiger should say. I'd think more of him if this was the statement:
"Good morning. I've already apologized countless times to those that deserve an apology for what I've done. It isn't enough, of course, but it's all I can do. To everyone else, I offer nothing. If you don't want to root for me on the golf course because of my indiscretions that is your right. But I won't apologize to you, just as I wouldn't expect you to apologize to me if you had 19 or 1,900 affairs. I play the game of golf better than anyone else has ever played it. That's where it ends when it comes to me and greatness. I'm just like the guy next to you on the subway when you take the club out of my hands. And if that realization means I'll never be in another commercial again it means I'll never be in another commercial again. I've been in plenty of them and look where it got me. So I'll just play golf now, and you will always wonder what it is I'm doing when I'm not golfing. That's OK, too. Thanks."
May not pass the focus group test but it would get him a little closer to Papelbon on the sound bite chart. That counts for something, doesn't it?
The guys react to what Don Banks had to say and get into some more thoughts on Deflategate. Are McNally and Jastremski ever going to break their silence and give their side of the story? Price says yes ... eventually.
Don Banks talks with the NFL Sunday boys about his reaction to Brady's appeal, where we go from here and the NFL's motives and decisions throughout the process. He also gets into the Pats offseason so far and their weakness at CB. Don gives his take on the AFC East this year and how some of the Pats' rivals have improved.
Greg and Price discuss their thoughts on some of the reports that have leaked after Tuesday from Brady's appeal hearing. The boys talk about what the reaction will be if Brady decides to accept a 1-game suspension. Fans want a complete exoneration, but there's a good chance that they won't get that - how will they react? They also talk with Mike Petraglia and get his thought on the appeal and more.
How long will this rebuild take? How much money will it take to keep Bae Crowder? Are Draft Picks even worth anything? With the Danny Ainge not landing any big names in the draft, and unable to lure any big names in free agency, Sam and Ben discussed if the Celtics are doomed moving forward.
Sam is joined by Jared Weiss from The Garden Report and CLNS Radio to breakdown game 4 of Cavs-Warriors, preview game 5 on Sunday, and analyze the Celtics needs this off-season.
Greg Dickerson and John Tomase discuss the amazing season for the Celts and if they have any chance against Lebron and the Cleveland Cavs in a seven game series. If they do, HOW ... how do they get it done?
Joe & Dave talked to the Red Sox slugger, whose 7th-inning homer took the lead back for good in the win over the Astros at Fenway.
Joe & Dave talked to the Sox starter, who threw a much-needed complete game win against the Astros at Fenway Park.
Joe and Rob Bradford talk with Red Sox outfielder Alejandro De Aza about the Red Sox solid road trip and offensive outpouring in a win against Toronto.
Don Sweeney, who was hired as the Bruins general manager yesterday speaks with Dale and Holley about his new position and where the Bruins go from here.
The awesomely knowledgeable Fluto Shinzawa calls DJ, Naoko and Pete to talk about his thoughts on the future of the B's. He discusses his column from earlier this week on Cam Neely wanting to give Claude the ax earlier in the season but not getting the ok. Fluto shares his thoughts on Chiarelli's firing, the future for Claude and where the Bruins should go from here. He also gives his opinion on potential moves the team can make, who would fit in here, his thoughts on the NHL playoffs so far and more.
In the final hour of the "midseason finale" as DJ likes to call it, the crew discuss more about the future of the Bruins franchise, the possible power struggle in the front office and who should be the head coach going forward. They talk to intelligent and talented Fluto Shinzawa about all of these thing and more in an excellent interview, and finally, DJ says THANK YOU!
Gary and Ben on the Pats.
The guys discussed the latest Red Sox news with Larry.
The top stories of the day as recounted by Gary Tanguay.
Conor McGregor has harsh words for Floyd Mayweather on Conan, Colbert hosts public access TV & will Joey Chestnut defend his title in Hot Dog Eating Contest?
Discussing Greg Monroe signing with Milwaukee and debating if that gives hope to a cold weather city in Boston
Kicking around the dream of acquiring a pitcher like Sonny Gray and how much you would have to give up in order to acquire that caliber talent
In honor of the 4th of July holiday, guest hosts Rob Bradford and Andy Hart examine the four worst renditions of the Star Spangled Banner at sporting events.
WEEI.com's Rob Bradford and Andy Hart of Patriots.com are in for Dale, Holley, and Thornton. Bradfo and Hart take some time to discuss the upcoming issues for Pats training camp, including what QB reps will be like between Brady and the backups.
Rob Bradford and Andy Hart are in for Dale, Holley, and Thornton and are joined by Houston Astros writer Evan Drellich of the Houston Chronicle to preview the weekend's Red Sox - Astros series as well as to get the inside word on the St. Louis Cardinals hacking scandal.
WEEI Bruins Reporter D.J. Bean joins Mikey Adams and Lenny Megliola to talk about the signing of winger Matt Beleskey on the opening day of NHL free agency.
With 80 games played for the Red Sox, Mikey Adams wants midterm grades for several players. Also, after another Rick Porcello clunker in Toronto, callers and texters give unflattering Porcello Limericks. Lenny Megliola and Textress Lucy are along.
Danny's early thoughts on Celtics drafting Terry Rozier at the 16th pick
Ben, Russ & Alex discuss the Revs continued downfall & argue over The Mighty Ducks movie franchise
Ken Laird and Ryan Hannable are joined by special guests Mike Mutnansky of the Red Sox Radio Network and Red Sox minor league hitting coordinator Tim Hyers to talk Sox prospects. What do the struggles of Rusney Castillo and Rick Porcello in the majors mean? Also, the international signing period begins July 2, looking back at past Latin American signings. And June selections for affiliate players of the month
How long will this rebuild take? How much money will it take to keep Bae Crowder? Are Draft Picks even worth anything? With the Danny Ainge not landing any big names in the draft, and unable to lure any big names in free agency, Sam and Ben discussed if the Celtics are doomed moving forward.
Ken Laird and Ryan Hannable are joined by special guests Mike Mutnansky of the Red Sox Radio Network and Red Sox minor league hitting coordinator Tim Hyers to talk Sox prospects. What do the struggles of Rusney Castillo and Rick Porcello in the majors mean? Also, the international signing period begins July 2, looking back at past Latin American signings. And June selections for affiliate players of the monthMore from this show
Gary and Ben on the Pats.More from this show
WEEI.com's Rob Bradford and Andy Hart of Patriots.com are in for Dale, Holley, and Thornton. Bradfo and Hart take some time to discuss the upcoming issues for Pats training camp, including what QB reps will be like between Brady and the backups.More from this show
Scott Cordishi is solo in studio while John Rooke is on the road. Scott takes your calls, texts, tweets and emails on the week's hot topics. It's Independence Day, time to celebrate our nation's birth with fireworks, parades and cookouts. The Red Sox are on the grill with their bait and switch routine, we love them…we hate them, what's a loyal fan to think?More from this show
Discussing Greg Monroe signing with Milwaukee and debating if that gives hope to a cold weather city in BostonMore from this show


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Simple Plan (Edited)
by Simple Plan
Released: Feb 2008
Label: Atlantic/Lava
When the chorus hits on the lead track to Simple Plan's self-titled LP, it's all guitars and grandeur, catchy enough to ensure yet another platinum LP and forceful enough to wallop the sniffling mall punks next to whom they often get filed. The band surprises with the increasingly sleek, nearly urban production of singles like "The End" or "Your Love Is a Lie" (a close cousin of Green Day's "Boulevard of Broken Dreams") and the echoing landscapes of "Holding On."
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Bridal Bliss: Just The Two Of Us view
What The Heart Wants view
Bridal Bliss: Just Go With It view
After one chance passing on their college campus, Will just couldn't get Angel off of his mind. They were officially introduced eight years later, and this time he left a lasting impression. Share their love!
"I have always loved the look of an underhand braid, so I wanted to try this look...
"I have always loved the look of an underhand braid, so I wanted to try this look with loose curls for my wedding day," says gorgeous bride Angel.
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Buena Vista Hires New Police Chief
Keith Hartman, a 23-year veteran of Newport News Police, began his new job June 1
Registration open for 2015 VACP Annual Conference in Williamsburg
The 90th Annual Conference of the Virginia Association of Chiefs of Police will be held August 30-September 2, 2015 at The Williamsburg Lodge. Registration is now open for delegates, guests AND exhibitors! We hope you can join us!
On June 1, 2015, the VACP/VPCF/VACLEA offices relocated to northern Henrico County.
Keeping Your Personal Information Private: Part 5
In Part 4, we talked about Defending against cyber stalking. At that time, and in most of the other parts of the series, we've talked about ways you can minimize the amount and type of your personal information that is available to be acquired by information brokers and others. The techniques we've shared and others we could talk about…
Athletes, volunteers sought for 2015 World Police & Fire Games in Fairfax
Athlete and volunteer registration now open at www.fairfax2015.com.
Be a role model: buckle up
Virginia's 2013 observed seat belt use rate is 79.7 percent. This number is helping to save lives on our roadways – but it could be higher, saving even more lives. We want to make sure both our motorists AND our officers are buckling up on every ride, in every vehicle. DMV's Virginia Highway Safety Office (VAHSO), the Virginia Association of…
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VIEWS: 56 PAGES: 69 POSTED ON: 8/12/2010 Public Domain
NetBeans IDE 5.0 Tutorial for Applets Fang Chu Kamolbhan Olapiriyakul NJIT Deployment Options There are at least three ways to put a NetBeans created applet on the NJIT AFS system. The first method is to create and test source code in NetBeans, but then transfer it to AFS, compile it there, and set it up manually. The second method is to create a JAR file in NetBeans, copy it to AFS, and configure it there with Netbeans. The third method is to package a stand-alone JAR package in NetBeans and deploy it to AFS. 2 8/12/2010 Contents of this presentation The detailed presentation, with code, uses the third option and is discussed last. The other two options are described briefly, along with explanatory material on Applets, AFS, and NetBeans, as an introduction to the final topic. 3 8/12/2010 Setting Up Java Applets on AFS Manually Fang Chu NJIT AFS and Java Applets To create a homepage on AFS for Java Class, see the instructions at http://web.njit.edu Your web pages will have an address like this http://web.njit.edu/~gblank Use FTP software or AFS Clients to upload your web pages to your directory http://csd.njit.edu/software http://www.coreftp.com/download.html 5 8/12/2010 AFS and Java Applets To run a Java applet on the web, you embed code similar to the following in an HTML file and then upload the file as a webpage. Applet Container Code Sample: <applet code="ReadFile.class" width=300 height=350> </applet> 6 8/12/2010 Running Java Applets on AFS Log on to AFS (afs1-afs32) Change to your java file directory Compile the java file Make sure that java file, java class file, text file and html applet container are in the same directory Link to the html applet container online to enable the java applet 7 8/12/2010 Log on to AFS Click on "Start" at bottom right Click on "Run" next to bottom 8 8/12/2010 Log on AFS Type in UCID and Pass word 9 8/12/2010 Change Directory Current Directory 10 8/12/2010 Change Directory Change directory to the folder containing "ReadFile.java" Using command "cd" 11 8/12/2010 Compile Java file Compile java file Using command "javac" No warning error info "ReadFile" generated! 12 8/12/2010 Run the Java Applet 13 8/12/2010 NetBeans Essentials for Java Applets Create or import Java applet codes. Debug, compile and run codes. Embed codes into web applications. 14 8/12/2010 Create/ Import Code Step1.Create a new project or open an existing project Step 2. Create a new java applet or open an existing file. 15 8/12/2010 Create a new project Select General>> Application>> Next>>… 16 8/12/2010 Name the new project After naming the project and selecting its directory Click on "finish" 17 8/12/2010 Create a new applet file Right-click on Source-package or new project name>> Right-click on "new">> Left-click on "Applet"; also name the package where the applet file and text file are saved. 18 8/12/2010 Compile an applet Right-click on the applet file and then left-click on "compile"to compile the java applet 19 8/12/2010 Compiling Message No Error, Can be built and executed 20 8/12/2010 Run the Java applet Include data.txt file in the same folder with java code. ―Build the project‖ by right-clicking on the project name node and then left-clicking it. ―Run the file‖, similar to ―compile‖. If applet program is correct, text will be displayed in the applet viewer. Otherwise, it may deliver a message in the bottom without initializing the applet. 21 8/12/2010 Applet Viewer After the project is built and executed, the text will be shown in the applet viewer. 22 8/12/2010 Web Applications Create a web project Choose File>New Project. Under Categories, select ―Web‖; under project, select ―Web Application‖; ―next‖ Under Project Name, type in a given name and then redirect the directory to the right folder; ―finish‖. 23 8/12/2010 Deploying JAR files on AFS Fang Chu NJIT Web Application When you want to include an applet JAR file in a web project, you can do so by adding the NetBeans IDE 5.x Java project that contains the JAR file, or by adding the JAR file itself. Note: if you adding the Java project to web project, you enable the IDE to build the applet whenever you build the web application. Therefore, when you modify the applet, the IDE builds a new version of the applet whenever the web project is built. On the other hand, if the applet JAR file is not in a NetBeans IDE 5.0 Java project, the applet source file is not rebuilt when you build the web project. 25 8/12/2010 Web Applications Step1: In the Projects window, right-click the project node and select Properties from the contextual menu. If the applet JAR file is in a NetBeans IDE 5.x Java project, click Packaging, and then click Add Project. Browse to and select the folder that contains the NetBeans IDE 5.x Java project. Note that NetBeans IDE 5.x projects are marked by the NetBeans IDE project icon. If the applet JAR file is not in a NetBeans IDE 5.x project, click Packaging, and then click Add JAR/Folder. Browse to and select the folder that contains the JAR file. 26 8/12/2010 Web Applications To embed the applet in an HTML file, right-click the project node, and choose New > File/Folder from the contextual menu. Under Categories, select Web. Under File Types, select HTML. Click Next. Give your HTML file a name and click Finish. Embed the following tags anywhere between the file's tags. <applet code="FileRead.ReadFile" archive="ReadFile.jar"> </applet> FileRead.ReadFile is the full class name ReadFile.jar is the JAR File that contains applet 27 8/12/2010 Deploying Web Applications Right-click the HTML node in the Projects window and choose Run File from the contextual menu. The server deploys the HTML file in the IDE's default browser. 28 8/12/2010 Success Similar page will be displayed if web applications run successfully. 29 8/12/2010 NetBeans IDE 5.0 Applet Deployment on AFS Kamolbhan Olapiriyakul NJIT Tutorial Outline Creating or importing an applet source file Creating a java project, create or import an applet source file Running and debugging an applet source file Run and applet source file, debug it by modifying its parameters in the src folder Embedding an applet in a web application Create a web project, import NetBeans IDE 5.0 Java project or a JAR file containing applet source files, add applet tags to a JSP file or HTML file, run the web project 31 8/12/2010 Creating the Java project from scratch or from existing sources Java project (file.java) can be created, compile, run and debugged in NetBeans environment A java project can contain the following: Java package Java class and interface Java applet Html file And more… 32 8/12/2010 Creating the Java project from scratch or from existing sources On the NetBeans main menu, choose File > New Project. Under categories, select General. Then, click Next. Choose one of the following: If you are creating a new applet, select Java Class Library under Projects. If you are importing an applet source, select Java Project with Existing Source and specify the file's location in the Source Packages Folder 33 8/12/2010 Creating the Java project from scratch or from existing sources Under Project Name, type project name. Change the project location if you want. Click Finish. If you imported an applet source file, run and debug it. 34 8/12/2010 Creating the applet source file Right-click to the project node in the Projects window and select New File/Folder Under Categories, select Java Classes. Under File Types, select Applet. Then click Next. Under Class Name, type file name. Under Package, type Package name. For example: File name ReadFile Package FileRead 35 8/12/2010 Sample source code: ReadFile Applet The ReadFile program reads a data text file from an applet the URL class is used for accessing web resources In this case, it also provides a method to obtain file access through an InputStream A BufferedReader provides buffering to smooth out the stream flow and to get the readLine() method for grabbing a whole line at once and returning it in a string 36 8/12/2010 Sample source code: ReadFile Applet package FileRead; Import java.applet.*; ... public class ReadFile extends java.applet.Applet { StringBuffer buffer; String filename="data.txt"; TextArea td; ... } 37 8/12/2010 Sample source code: ReadFile Applet public void init() { td = new TextArea(60, 20); td.setEditable(false); setLayout(new BorderLayout()); add(td, "Center"); //read the file readFile(); } 38 8/12/2010 Sample source code: ReadFile Applet public void readFile(){ String line; URL url = null; try { url = new URL (getCodeBase(), filename); } catch (MalformedURLException e ) { System.out.println("Malformed URL "); stop(); } 39 8/12/2010 Sample source code: ReadFile Applet try { InputStream in = url.openStream(); BufferedReader bufin = new BufferedReader(new InputStreamReader(in)); buffer = new StringBuffer () ; while ((line = bufin.readLine()) != null){ buffer.append(line + "\n"); } in.close(); } catch (IOException e ) {} tdisplay.append(buffer.toString ()); } 40 8/12/2010 Build and run applet source file After the applet source file has been created, you can build and run the applet source file on NetBeans IDE After the project is built and the applet is complied and run, an applet viewer is shown in small window frame If the applet viewer is not successfully loaded, this means that there is an error in your code 41 8/12/2010 Build and run applet source file Right-click the project node and choose Build Project from the contextual menu The ReadFile.jar file is created in the dist folder Right-click the applet class node and choose Run File from the menu 42 8/12/2010 Build and run applet source file The ReadFile.html launcher file, with the applet embedded, is created in the build folder The applet is launched in the Applet viewer as shown in the left figure 43 8/12/2010 Debug the applet source file by modifying its parameters The ReadFile.html launcher file in build folder is overwritten each time when run or debug the applet Therefore, do not modify the launcher file in build folder 44 8/12/2010 Debug the applet source file by modifying its parameters Instead, use the following procedures: Open the Files window Copy the ReadFile.html from build folder to the package where the applet class lives in the src folder. Make sure that ReadFile.html launcher file has the same name as the applet class Edit the ReadFile.html launcher file as needed When the project is built, the ReadFile.html launcher file is copied from the src folder to the build folder 45 8/12/2010 Create the applet-embedded Web Application You can create a Web page that contains HTML source code and Java files by using the NetBeans IDE Java applets can be attached on the HTML source file The HTML page can be view on the default Web browser or the Web browser of your choice To set up the default Web browser, go to Option on the menu 46 8/12/2010 Create the applet-embedded Web Application In the General tab, you will see the Web Browser drop-down box in the General section Choose the Web browser Note: Java applet works well on Mozilla Firefox, instead of Internet Explorer 47 8/12/2010 Create the applet-embedded Web Application On the NetBeans main menu, choose File > New Project. Under categories, select Web. Under Projects, select Web Application. Then, click Next. Under Project Name, type project name. Change the Project Location to any folder you need. Then click Finish. 48 8/12/2010 Add the applet JAR file to the web project You can either add the NetBeans IDE Java project that contains the JAR files, or add the JAR file itself Note: if you add the Java project to web project, you enable the IDE to build the applet whenever you build the web application. Therefore, when you modify the applet, the IDE builds a new version of the applet whenever the web project is built. On the other hand, if the applet JAR file is not in a NetBeans IDE 5.0 Java project, the applet source file is not rebuilt when you build the web project. 49 8/12/2010 Add the applet JAR file to the web project In the Projects window, right-click the project node and select Properties from the contextual menu Choose one of the following: If the applet JAR file is in a NetBeans, click Packaging, and then Add project. Browse to and select the folder that contains java project. If the applet JAR file is not in a NetBeans, click Packaging, and then click Add JAR/Folder. Browse to and select the folder that contains JAR file. 50 8/12/2010 Add the applet JAR file to the web project Optionally, you can type a location for the applet in the table's Path in WAR column. By default, the applet JAR file will be copied to build/web folder. Click OK Note: When you build the project, the applet's JAR file is packaged in the project's WAR file in the dist folder and also in build/web folder. 51 8/12/2010 Create and run the JSP file or HTML file Choose one of the following: Embed the applet in a JSP file, double-click default index.jsp file in the Projects window. This file is created by the IDE. Embed the applet in a HTML file, right-click the project node, and choose New > File/Folder from the menu. Under Categories, select Web > HTML. Click Next and Finish. 52 8/12/2010 Create and run the JSP file or HTML file Embed the applet in the file by adding the following applet tag anywhere between the file's  tags: <applet code="FileRead.ReadFile" archive="ReadFile.jar"> </applet> FileRead.ReadFile is the full class name ReadFile.jar is the JAR File that contains applet Right-click the JSP or HTML node in the Projects window and choose Run File from the menu 53 8/12/2010 Output 54 8/12/2010 Deploy the NetBeans Java Project on AFS Kamolbhan Olapiriyakul NJIT Create the links to Java projects on AFS Create a Webpage for course The course main page should be named as index.html For example: CS602/index.html Creates the underlying Web pages that link with the course main page Sample code for the link command is:  56 8/12/2010 Transfer Java project and files to AFS Clients To transfer Java projects to AFS Clients, you need to have File Transfer Protocol (FTP) or AFS Clients software. The FTP and AFS Clients allows you to transfer or exchange files between your computer and AFS servers. You can download AFS Clients at http://csd.njit.edu/software See also the installation and setup instruction at http://web.njit.edu/all_topics/AFS/windows.client/ You can also download the Core FTP at http://www.coreftp.com/download.html 57 8/12/2010 Transfer file to AFS Clients The path for your AFS personal space should be \afs\cad\u\first_letter_UCID\second_letter_UCID\UCID For example, the personal space for UCID ―ab12‖ can be found at afs\cad\u\a\b\ab12 Transfer the project folder from your computer to your AFS space. For example, the ReadFile project are transferred to personal homepage folder on AFS or public_html folder 58 8/12/2010 Transfer file to AFS Clients Create sub-folder if necessary. For instance, sub-folder CS602 is created to store project files The path of project, for instance, is http://web.njit.edu/~ab12/CS602/ReadFile/ 59 8/12/2010 Trouble Shooting Section Fang Chu Kamolbhan Olapiriyakul Also see the separate presentation on ―Applet Failures‖ NJIT Frequently Asked Questions There is an ―x‖ in the applet viewer. Was it initialized?—Both applet structure and code needs to be double checked. The applet runs in NetBeans, but it is not working with AFS.—Check links to see if it is directed to the folder where source and class files are stored. Or transfer codes from NetBeans to server account to compile java file via AFS to see if it is working. 61 8/12/2010 FAQ Applet works with Firefox, but not IE.– IE may require a manifest file with a blank line for a JAR file. See details in the tutorial on JAR files. A Java applet may not work in a browser due to browser configuration, security settings, lack of the Java Runtime Edition, or another incompatibility. Netbeans allows you to specify a browser. Try both and compare the code, especially the deployment descriptor and HTML code. 62 8/12/2010 FAQ Cannot embed applet in the HTML file Check the code between <applet> </applet> tag Different IDE may have slightly different standard of code for applet command Input is accepted in NetBeans but not AFS.– Check the I/O program structure in the code to see if there is a missing request/accept module. 63 8/12/2010 FAQ The following messages have been found: ―The applet is not initialized‖ ―Loading Java applet failed‖ Try to run applet on NetBeans first Check the path and syntax of the code 64 8/12/2010 Reference www.netbeans.org NetBeans quick-start tutorials, open source downloads and FAQ sessions and a particular chapter highlighting applets. java.sun.com/developer/onlineTraining/tools/netbe ans_part1 Quick-start tutorials for NetBeans users and professional developers' forum where many topics are around applets. 65 8/12/2010 Reference www.cs.armstrong.edu/liang/intro5e/Suppl ementINetBeans.pdf http://www.javapassion.com/netbeans/ma sterindex.html Comprehensive NetBeans introductions with emphasis on Java programming and many samples on Java applets. 66 8/12/2010 Reference http://docs.rinet.ru/J21/ch8.htm http://math.hws.edu/javamath/ Comprehensive Java Applets samples can be found along with detailed documentation, which can be practiced with NetBeans. 67 8/12/2010 Reference NetBeans IDE 5.0 Quick start guide for J2EE Application http://www.netbeans.org/kb/50/quickstart- j2ee.html NetBeans IDE 5.0 Software download. http://www.netbeans.org/kb/55/tutorial- webapps.html NetBeans tutorial for Applet http://www.netbeans.org/kb/50/tutorial- applets.html 68 8/12/2010 Reference NetBeans Web Application tutorial http://www.netbeans.org/kb/55/tutorial- webapps.html AFS Window Client Software http://web.njit.edu/all_topics/AFS/windows.client/ Core FTP Software http://www.coreftp.com/download.html ReadFile source code http://www.particle.kth.se/~fmi/kurs/PhysicsSimu lation/Lectures/12B/fileReadByApplet.html 69 8/12/2010
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Original recipe yields 8 servings
Amount per serving ({{servings}} total)
Based on a 2,000 calorie diet
Ready In
The only way the pudding could be bland tasting is if you use bottled lemon juice. I used fresh squeezed lemon juice and also used cream not milk. (Once in awhile you just have to give flavor ...
I made this for my husband's birthday tonight. I followed the recipe exactly. We ate it fresh out of the oven, and between two adults and two toddlers, it was gone within ten minutes. The cake l...
Fantastic pudding cake! The cake was really light and airy, and the pudding was tart and sweet. I followed the recipe exactly and it turned out delicious. Definitely a keeper!


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Pending Arrangements (Oct 17)
Edmond Bingham
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text: 0 Movies Back to article: Star Wars Episode 7 rumored cast: Zac Efron, Benedict Cumberbatch, more 0 Previous Next Benedict Cumberbatch Mere months after Cumberbatch made waves as Star Trek Into Darkness's rebooted Khan, a report surfaced that he was in line for a similarly dastardly role in Abrams' new Star Wars. The notion of the two franchises sharing a major villain seems wrong, but there's already so much crossing of the streams going on that it's not remotely inconceivable, and Cumberbatch himself has been very coy about the rumours, confirming only that "no offer had been made" as of last autumn. Copyright: Adriana M. Barraza/WENN.com 6 of 15 Previous Next


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Fort Lauderdale, FLUSA
Hometown: Fort Lauderdale
March 23, 2013
I have never done SUP before... I'd like to try with a group , can I join and do I have to bring a board , or does this group rent out some?
I love the ocean and all water activity . I never try SUP but I'd like to try with a group ..
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Picadillo-Stuffed Peppers
Total Time:
Level: Moderate
Serves: 6
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- 6 medium peppers
- 1 jar green and black olive pasta sauce
- 1 lb. Lean Ground Beef
- 2 small zucchini
- 1.50 c. chopped onions
- 2 tsp. minced garlic
- 0.50 tsp. ground cinnamon
- 0.50 tsp. cumin
- 0.50 tsp. salt
- 0.50 tsp. Pepper
- 0.33 c. raisins
- 1 tbsp. cider vinegar
- 1 tbsp. sugar
- 2 tsp. olive oil
- Cut 1⁄4 off stem end of peppers; remove seeds. Stand peppers and tops in a microwave-safe baking dish. Add 1⁄2 cup water, cover with vented plastic wrap and microwave on high 5 minutes, or until peppers are crisp-tender. Stir 1 1⁄2 cups pasta sauce into water in dish.
- Meanwhile, sauté beef, zucchini and onions in a large nonstick skillet over medium-high heat, breaking up meat, 7 minutes, or until beef is no longer pink and vegetables are almost tender.
- Stir in garlic, cinnamon, cumin, salt and pepper; cook 1 minute until fragrant. Remove from heat; stir in raisins, vinegar, sugar and remaining sauce. Spoon into peppers; replace tops. Cover tightly and refrigerate up to 2 days.
- To bake: Heat oven to 400°F. Uncover baking dish; brush peppers with the oil. Bake uncovered 30 minutes, or until sauce bubbles and pepper tops are lightly charred.
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Y Ono and T Mori contributed equally to this study, and both should be regarded as the first authors.
Long-term follow-up of reduced-intensity allogeneic hematopoietic stem cell transplantation for refractory or relapsed follicular lymphoma†
Article first published online: 5 JUN 2012
DOI: 10.1002/ajh.23261
Copyright © 2012 Wiley Periodicals, Inc.
American Journal of Hematology
Volume 87, Issue 9, pages 929–931, September 2012
Additional Information
How to Cite
Ono, Y., Mori, T., Kato, J., Yamane, A., Shimizu, T., Kikuchi, T., Kohashi, S. and Okamoto, S. (2012), Long-term follow-up of reduced-intensity allogeneic hematopoietic stem cell transplantation for refractory or relapsed follicular lymphoma. Am. J. Hematol., 87: 929–931. doi: 10.1002/ajh.23261
- †
Conflict of interest: Nothing to report.
Publication History
- Issue published online: 23 AUG 2012
- Article first published online: 5 JUN 2012
- Accepted manuscript online: 14 MAY 2012 05:25AM EST
- Manuscript Accepted: 2 MAY 2012
- Manuscript Revised: 29 APR 2012
- Manuscript Received: 2 MAR 2012
Although allogeneic hematopoietic stem cell transplantation (HSCT) is considered the only curative treatment for refractory or relapsed follicular lymphoma (FL), transplant-related mortality (TRM) greatly interferes with the success. A variety of reduced-intensity conditionings (RICs) have been used to reduce TRM, but an optimal conditioning for FL has not been fully established. We retrospectively evaluated the outcome of allogeneic HSCT for FL with RIC consisting of fludarabine and melphalan. Nineteen adult patients with relapsed or refractory FL were conditioned with fludarabine (125 mg/m2) and melphalan (140 mg/m2), and received grafts from an HLA-identical sibling (n = 6) or an unrelated donor (n = 13). For the prophylaxis of graft-versus-host disease (GVHD), cyclosporine A or tacrolimus with short-term methotrexate was given. There were no early deaths before engraftment, and all patients achieved engraftment. Three patients died of extensive-type chronic GVHD (n = 2) or bacterial infection (n = 1) without disease progression. With a median follow-up period of 75.2 months (range: 33.3–111.9 months), 16 patients were alive without disease progression. Both the 5-year overall and progression-free survival rates were 84.2% (95% CI: 67.7–100%). These results strongly suggest that allogeneic HSCT with RIC using fludarabine and melphalan could be a promising treatment choice for refractory or relapsed FL.
Current chemotherapies, such as rituximab-containing regimens, have improved the prognosis of follicular lymphoma (FL). However, FL is generally considered incurable with these conventional treatments, and the disease relapses in most patients [1]. High-dose chemotherapy with autologous or allogeneic hematopoietic stem cell transplantation (HSCT) has been shown to improve the survival rates of relapsed or refractory FL [2, 3]. When compared with autologous HSCT, a significant reduction in relapse rate has been observed after allogeneic HSCT with myeloablative conditioning [4–6]. The suggested mechanism of the reduced relapse rate is the graft-versus-lymphoma (GVL) effect provided by transplanted donor cells. However, this favorable effect is often offset by the high transplant-related mortality (TRM) of allogeneic HSCT following myeloablative conditioning. To reduce TRM, most of the recent studies have focused on the use of reduced-intensity conditioning (RIC). The outcomes are promising and the practice of allogeneic HSCT has shifted in favor of RIC, although registry data showed an increased risk of late disease progression after RIC regimens [7, 8]. The definition of RIC included a variety of regimens which varied significantly in their intensity and immunosuppressive effects. Thus, the optimal RIC regimens of allogeneic HSCT for FL have yet to be established, and long-term follow-up is also lacking in most of the earlier studies. Therefore, we retrospectively evaluated the long-term outcome of allogeneic HSCT with RIC consisting of fludarabine and melphalan for relapsed or refractory FL.
Nineteen patients with histologically proven FL without transformation who underwent allogeneic HSCT at Keio University Hospital (Tokyo, Japan) between June 2002 and January 2009 after being conditioned with fludarabine and melphalan were evaluated. No patients received anti-thymocyte globulin (ATG) as part of the conditioning regimen. The patient and transplant characteristics are shown in Table I. None of the patients were in complete remission (CR) at the time of transplant. Most of the patients had received multiple lines of chemotherapy; two had received autologous and two had received allogeneic HSCT. In the two patients who had undergone allogeneic HSCT, the graft was rejected along with the recovery of autologous hematopoiesis after conditioning with fludarabine and cyclophosphamide. Both patients experienced disease progression thereafter and decided to undergo the second allogeneic HSCT from the same HLA-identical sibling and a different HLA-matched unrelated donor, respectively. Thirteen patients received stem cells from an unrelated donor.
|Median age (range)
|47 (34–58)
|Disease status at transplant
|Partial remission
|Progressive disease
|Stable disease
|No. of lines of prior chemotherapy
|3 or less
|4 or 5
|6 or more
|Allograft (graft rejection)
|Stem cell donor
|Related (BM/PBSC)
|6 (4/2)
|Unrelated BM
|GVHD prophylaxis
|CsA and methotrexate
|Tacrolimus and methotrexate
In all 19 patients, engraftment was achieved at a median of 19 (range, 13–25) days after transplantation, and full donor chimerism was also confirmed within 28 day after transplantation. No patients received donor lymphocyte infusion (DLI). Incidences of acute GVHD were Grade 0–1 in 10 (53%), Grade 2 in 8 (42%), and Grade 3 in 1 patient (5%). The patient who developed Grade 3 acute GVHD received peripheral blood stem cells from an HLA-identical sibling donor. Cumulative incidence of any type of chronic GVHD was 61.1% (95% CI: 38.6–83.6%).
The transplant procedure was generally well-tolerated. Grade 3 or greater organ toxicities consisted of oral mucositis (n = 4), diarrhea (n = 7), hepatotoxicity (n = 7), and nephrotoxicity (n = 1). All these toxicities were reversible and manageable with supportive care. No patients developed hepatic veno-occlusive disease/sinusoidal obstruction syndrome. Post-transplant infectious complications were cytomegalovirus (CMV) infection (n = 8), CMV gastrointestinal diseases (n = 3), viral hemorrhagic cystitis (n = 6), and bacterial infection (bacteremia: n = 4; pneumonia: n = 2; enterocolitis: n = 1). The follow-up period of the 16 patients who were alive at the time of analysis ranged from 33.3 to 111.9 months with a median of 75.2 months. There were three cases of TRM, and the causes were bacterial infection (bacteremia; n = 1) and extensive-type chronic GVHD involving the gastrointestinal tract (n = 1) or liver (n = 1). One patient who developed fatal bacteremia due to Escherichia coli had a 7-year history of chemotherapy for FL and developed Grade 3 mucositis after transplantation. No patients showed disease relapse or progression, and thus the 5-year overall survival (OS) and progression free survival (PFS) rates were both 84.2% (95% CI: 67.7–100%; Fig. 1). All surviving patients had an Eastern Cooperative Oncology Group (ECOG) performance status of 0 (n = 14) or 1 (n = 2), and none of the patients were receiving immunosuppressive therapy at the time of analysis. There was no case of secondary cancer during the follow-up.
The results of this study suggest that RIC consisting of fludarabine and melphalan offers promise as a conditioning regimen for patients with relapsed or refractory FL undergoing allogeneic HSCT by providing a high PFS rate (84%) with a low TRM. The most notable finding was that disease progression was not observed in any of the patients even with a long-term follow-up (median 75 months). In contrast to other studies including relatively high proportion (20–60%) of patients in CR [7–13], no patients in CR were included in our cohort. However, our results were comparable to or more favorable than those of the studies showing the PFS rates ranging between 32% and 84%. In these studies, the RIC regimens used for FL were quite variable, and included fludarabine-based regimens in which fludarabine was combined with cyclophosphamide, low-dose TBI, busulfan or melphalan, and BEAM. Khouri et al. [9] reported a favorable outcome by using fludarabine and cyclophosphamide in combination with pre- and post-transplant rituximab [13]. In addition, some of these RIC regimens were incorporated with alemtuzumab or ATG for in-vivo T-cell depletion. The degrees of anti-lymphoma effects, myelosuppression, immunosuppression, and organ toxicity vary significantly among these RIC regimens, making it difficult to compare the results of allogeneic HSCT using different RIC regimens for FL. The combination of fludarabine and melphalan used in this study achieved full donor chimerism shortly after transplantation without DLI, and disease progression was not observed in any of the patients, suggesting its considerable immunosuppressive effect and intensive anti-leukemia/lymphoma effect [14]. Since DLI required for the conversion to full donor chimerism has the potential to cause serious GVHD, this regimen can be a good candidate for the conditioning regimen in this setting.
In this study, CSA or tacrolimus with short-term methotrexate was used for the prophylaxis of GVHD. It is notable that the incidence of severe acute GVHD was low among the two thirds of patients receiving HSCT from unrelated donors, which could partly explained by the use of tacrolimus for the prophylaxis of GVHD for HSCT from unrelated donors and the ethnic background [15–18]. In contrast, more than half of evaluable patients developed extensive-type chronic GVHD, and accounted for two of the three deaths observed in this study. There is a possibility of increase in disease relapse using highly intensive immunosuppressive therapies such as in vivo or in vitro T-cell depletion to prevent GVHD. However, FL has been shown to be highly sensitive to the GVL effect [19].Therefore, more intensive immunosuppression could improve the survival by decreasing severe life-threatening GVHD. The use of ATG could be an option, since it has been reported that a conditioning regimens including ATG could decrease the incidence of extensive-type chronic GVHD [20]. While maintaining a balance with the anti-lymphoma effects of fuldarabine plus melphalan, future studies should focus on optimizing the prophylaxis and treatment of GVHD.
In conclusion, allogeneic HSCT following RIC consisting of fludarabine and melphalan could be a promising conditioning regimen for refractory or relapsed FL with adequate supportive care. Future studies will be needed to optimize the post-transplant immunosuppression in this setting.
Study patients
This study retrospectively evaluated patients with histologically proven FL without transformation who underwent allogeneic HSCT including bone marrow transplantation (BMT) or peripheral blood stem cell transplantation (PBSCT) at Keio University Hospital (Tokyo, Japan). Data were collected from institutional data bases and medical records.
Conditioning regimen and HSCT procedure
Fludarabine at a dose of 25 mg/m2/day was administered intravenously over 30 min on days 6 through 2. Melphalan at a dose of 70 mg/m2/day was given intravenously over 15 min on days 3 and 2. Four Gy of total body irradiation (TBI) was delivered in two fractions in one patient who underwent second HSCT from the same sibling donor to prevent graft rejection. Two days after the completion of fludarabine and melphalan, patients received BMT or PBSCT. The types of donor and human leukocyte antigen (HLA) compatibility were either HLA-A, -B or -DR identical sibling, or HLA-A, -B or -DR serologically-matched unrelated donor. In 13 patients who received the graft from an unrelated donor, HLA-DRB1 alleles were further typed using high-resolution DNA techniques in all patients and HLA-A and -B alleles were typed using high-resolution DNA techniques only in seven patients who underwent HSCT later than August 2005. With these limited data, HLA disparity was HLA-A allele mismatch in two patients, and HLA-DRB1 allele mismatch in one patient. T-cell depletion of the graft was not performed in any of the patients. For the prophylaxis of graft-versus-host disease (GVHD), patients received cyclosporine A (CSA: 3 mg/kg/day by continuous infusion) or tacrolimus (0.03 mg/kg/day by continuous infusion) starting on day-1 with short-term methotrexate (15 mg/m2 on day 1, and 10 mg/m2 on days 3 and 6). For HSCT from an unrelated donor, tacrolimus was selected and additional methotrexate (10 mg/m2) was given on day 11. Each patient was isolated in a laminar air-flow room and received prophylactic antibiotics and antifungal agents orally. The administration of lenograstim at a dose of 5 μg/kg was initiated 1 day after HSCT and continued until neutrophil recovery was achieved. After April 2003, oral cryotherapy was applied for the prophylaxis of oral mucositis due to high-dose melphalan as we previously described [21, 22].
Regimen-related toxicity, engraftment, chimerism, and GVHD
Regimen-related organ toxicities were graded according to the Common Terminology Criteria for Adverse Events ver 4.0. The day of myeloid engraftment was defined as the first day of three consecutive days when the absolute neutrophil counts exceeded 0.5 × 109/L. Chimerism analyses were performed by means of fluorescence in-situ hybridization for X and Y chromosomes or by microsatellite polymerase chain reaction (PCR) as appropriate. For PCR, DNA was obtained from the recipients' and donor's blood before transplantation. PCR of short tandem repeat units was performed using DNA extracted from the unfractionated bone marrow after transplantation. Both acute and chronic GVHD were diagnosed and graded based on the published criteria [23, 24].
Statistical analysis
The OS, PFS, and cumulative incidence of chronic GVHD were calculated by the Kaplan–Meier method.
- 1Treatment strategies in follicular lymphomas: Current status and future perspectives. J Clin Oncol 2005; 23: 6394–6399., , , et al.
- 2Role of allogeneic transplantation in low-grade lymphoma and chronic lymphocytic leukemia. Curr Opin Hematol 2006; 13: 273–279., .
- 3The role of cytotoxic therapy with hematopoietic stem cell transplantation in the treatment of follicular lymphoma: An evidence-based review. Biol Blood Marrow Transplant 2007; 16: 443–468., , , et al.
- 4Allogeneic versus autologous bone marrow transplantation for refractory and recurrent low-grade non-Hodgkin's lymphoma. Blood 1997; 90: 4201–4205., , , et al.
- 5Long-term results favor allogeneic over autologous hematopoietic stem cell transplantation in patients with refractory or recurrent indolent non-Hodgkin's lymphoma. Ann Oncol 2003; 14: 737–744., , , et al.
- 6Comparison of autologous and allogeneic hematopoietic stem cell transplantation for follicular lymphoma. Blood 2003; 102: 3521–3529., , , et al.
- 7Allogeneic transplants in follicular lymphoma: Higher risk of disease progression after reduced-intensity compared to myeloablative conditioning. Biol Blood Marrow Transplant 2008; 14: 236–245., , , et al.
- 8Chemoresistant or aggressive lymphoma predicts for a poor outcome following reduced-intensity allogeneic progenitor cell transplantation: An analysis from the Lymphoma Working Party of the European Group for Blood and Bone Marrow Transplantation. Blood 2002; 100: 4310–4316., , , et al.
- 9Nonablative allogeneic hematopoietic transplantation as adoptive immunotherapy for indolent lymphoma: Low incidence of toxicity, acute graft-versus-host disease, and treatment-related mortality. Blood 2001; 98: 3595–3599., , , et al.
- 10Long-term outcomes after reduced-intensity conditioning allogeneic stem cell transplantation for low-grade lymphoma: A survey by the French Society of Bone Marrow Graft Transplantation and Cellular Therapy (SFGM-TC). Haematologica 2007; 92: 627–634., , , et al.
- 11T-cell-depleted reduced-intensity transplantation followed by donor leukocyte infusions to promote graft-versus-lymphoma activity results in excellent long-term survival in patients with multiply relapsed follicular lymphoma. J Clin Oncol 2010; 28: 3695–3700., , , et al.
- 12Outcome of BEAM-autologous and BEAM-alemtuzumab allogeneic transplantation in relapsed advanced stage follicular lymphoma. Br J Haematol 2008; 141: 235–243., , , et al.
- 13Eight-year experience with allogeneic stem cell transplantation for relapsed follicular lymphoma after nonmyeloablative conditioning with fludarabine, cyclophosphamide, and rituximab. Blood 2008; 111: 5530–5536., , , et al.
- 14Melphalan and purine analog-containing preparative regimens: Reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation. Blood 2001; 97: 631–637., , , et al.
- 15Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation. Blood 1998; 92: 2303–2314., , , et al.
- 16Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors. Blood 2000; 96: 2062–2068., , , et al.
- 17Phase III study comparing tacrolimus (FK506) with cyclosporine for graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation. Bone Marrow Transplant 2001; 28: 181–185., , et al.
- 18Comparison of graft-versus-host-disease and survival after HLA-identical sibling bone marrow transplantation in ethnic populations. Blood 2005; 105: 1408–1416., , , et al.
- 19Graft-versus-lymphoma effect of donor lymphocyte infusion in indolent lymphomas relapsed after allogeneic stem cell transplantation. Bone Marrow Transplant 2003; 32: 1159–1163., , , et al.
- 20Antithymocyte globulins and chronic graft-vs-host disease after myeloablative allogeneic stem cell transplantation from HLA-matched unrelated donors: A report from the Societe Francaise de Greffe de Moelle et de Therapie Cellulaire. Leukemia 2010; 24: 1867–1874., , , et al.
- 21Oral cryotherapy for the prevention of high-dose melphalan-induced stomatitis in allogeneic hematopoietic stem cell transplant recipients. Support Care Cancer 2005; 13: 266–269., , , et al.
- 22Brief oral cryotherapy for the prevention of high-dose melphalan-induced stomatitis in allogeneic hematopoietic stem cell transplant recipients. Support Care Cancer 2006; 14: 392–395., , , et al.
- 23Consensus conference on acute GVHD grading. Bone Marrow Transplant 1995; 15: 825–828., , , et al.
- 24Chronic graft-versus-host syndrome in man: A long-term clinicopathologic study of 20 Seattle patients. Am J Med 1980; 69: 204–217., , , et al.
Yukako Ono*, Takehiko Mori*, Jun Kato*, Akiko Yamane*, Takayuki Shimizu*, Taku Kikuchi*, Sumiko Kohashi*, Shinichiro Okamoto*, * Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.


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Alexandra Reeve Givens & Husband Welcome First Child: Christopher Russel ReeveRead More » »
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Congratulations to Ali Landry and Alejandro Monteverde. The former model and actress, 39, and her director husband welcomed their third child — and son named Valentin Francesco Monteverde – on Thursday, July 11, PEOPLE reports.
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Ali Landry's Lil' Beach Boy
Expectant mom Ali Landry shared a sweet photo of 19-month-old Marcelo via Twitter on Tuesday (May 21). She wrote: "Marcelo loving his day at the beach with his papa!" View Slideshow »» View All Photos »»
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Former Miss USA Ali Landry, 39, recently shared this classic black and white instragram of her husband Alejandro Monteverde and their two children Estela, 5, and 1-year-old Marcelo. "Cannot wait for the kids to see Santa Paws " she wrote.
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Proud mom Ali Landry shared a sweet snapshot with 1-year-old son Marcelo dressed up as Mickey Mouse. "Oh no, there is a mouse in the house," the mom-of-two joked via Instagram. View Slideshow »» View All Photos »»


text: 33 HXYT-International-Cultule-Exchange-Center Jobs | HXYT-International-Cultule-Exchange-Center Vacancies Contact us Register Login Home Employers Jobseekers News Partners Rec Agencies Login You are currently not logged in post all your employers jobs for free attracting 80 million job searches every month Access our expert agency partners Features 1 2 3 4 5 6 7 8 9 10 11 Employers Jobs You are here : Home / Search results Filter by: relevance title salary employer date oral english teachers needed, 2011 fall's semester in public schools of China employer: HXYT International Cultule Exchange Center location: various cities of China salary: on application description: Hi!Dear friends, thanks for reading my Ads. I wish everything goes well with you all! Do you want to be an English teacher in China with a favorable income? Do you want to experience exotic life in China? If your answer is YES, come and join us quickly. We may help you realize your thoughts. 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Gen. Petraeus is okay
A scare this morning on Capitol Hill — Gen. David Petraeus passed out briefly while testifying at a Senate committee hearing. He reportedly had not had anything to drink or eat before taking the mic.
The Hill reports that he was able to walk out of the hearing room on his own accord.
WaPo: "Sen. Carl Levin, chairman of the committee, said Petraeus 'appears to be doing very well.'"
Video via Weekly Standard:
The committee is in recess.
Gatorade and Power Bars, stat.
10:52am. Petraeus has returned to the hearing room. He looks fine, thank goodness. Hearing will be postponed until tomorrow.
Jen Psaki issues stern warning to hospital zealots who might try to derail John Kerry's Iran nuke negotiations
May 31, 2015 09:42 PM by Doug Powers
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May 26, 2015 09:39 AM by Michelle Malkin
Memorial Day 2015: Honoring the fallen
May 24, 2015 09:03 PM by Michelle Malkin
Obama: U.S. not losing to ISIS, but definitely getting pushed around by 'climate change'
May 21, 2015 08:21 PM by Doug Powers
As ISIS overruns Anbar province in Iraq, Obama stays focused on the real threat
May 20, 2015 07:55 AM by Doug Powers
Categories: Barack Obama, Iraq, Terrorist attacks


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February 22, 1995 in Nation/World
Commercial-Free TV
It could be paradise: No repetitive jingles singing the praises of the latest cereal, no interruptions to that cliff-hanger season finale.
To the delight of millions of television viewers - and the dismay of already cash-strapped TV companies Russian state television has announced a temporary ban on all commercials on its stations.
Russia's mammoth state television network, Ostankino, issued a statement Monday night saying ads were "the source of great irritation and disappointment" and banning them "until strict rules are set up to regulate advertisements in the interests of … ethical standards."
An Ostankino spokeswoman wouldn't give the reason for the ban, or say when it will take effect.
© Copyright 1995 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.


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Tag Archives: Wonderful Halos
Fitness Trainer and Wonderful Halos Kick off Health Initiative
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New Wonderful Halos Mandarins Arrive In Stores Nationwide
The makers of Wonderful Pistachios and POM Wonderful have announced the arrival of their new mandarin brand, Wonderful Halos, now available in produce aisles … Continue reading


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restricted free agency
Flyers sign budding star James van Riemsdyk to a six-year, $25.5M contract extension
Aug 30, 2011, 1:10 PM EDT
The Flyers are buying in to the notion that James van Riemsdyk is primed for stardom; they signed the budding power forward to a six-year deal worth $25.5 million.
Report indicates little progress between Brad Marchand, Bruins; Should Tyler Ennis be watching?
Aug 21, 2011, 9:11 PM EDT
The Boston Globe reports that there have been few signs of progress in the contract talks between Brad Marchand and the Bruins. Fluto Shinzawa also goes on to compare Marchand with Tyler Ennis, who will be an RFA next summer – but is it really a valid comparison?
Leafs assistant GM Dave Nonis optimistic about Luke Schenn and Matthew Lombardi
Aug 18, 2011, 9:46 PM EDTComments Off on Leafs assistant GM Dave Nonis optimistic about Luke Schenn and Matthew Lombardi
Maple Leafs assistant GM Dave Nonis said that the team should agree to a new contract with Luke Schenn before training camp. Nonis also had a vague but optimistic report about Matthew Lombardi.
Buffalo Sabres sign Marc-Andre Gragnani to one-year deal, must clean up salary cap mess
Aug 11, 2011, 4:28 PM EDT
The good news is that Sabres re-signed Marc-Andre Gragnani to a one-year contract. The bad news is that they're hovering high above the salary cap ceiling this summer and will face some tough decisions next off-season as well.
Brad Marchand discusses contract negotiations, 'mutual respect' among rivals
Aug 4, 2011, 5:42 PM EDT
Brad Marchand spoke about his contract situation, as well as his relationship with Sidney Crosby, Jonathan Toews and P.K. Subban.
With negotiatons stalling, Luke Schenn's agent says that new contract might be an 'August issue'
Jul 26, 2011, 11:40 PM EDTComments Off on With negotiatons stalling, Luke Schenn's agent says that new contract might be an 'August issue'
There hasn't been much progress in contract talks between the Maple Leafs and Luke Schenn, leading his agent to imply that it will take until August. That being said, he should remain in Toronto for at least the short-term future.
Shea Weber, Predators currently locked in a 'stalemate' regarding a new contract
Jul 20, 2011, 1:37 PM EDTComments Off on Shea Weber, Predators currently locked in a 'stalemate' regarding a new contract
Both sides have been saying all the right things, until now: Shea Weber's agent claims the sides have hit "a bit of a stalemate" in their contract discussions. This post covers the Predators' big three headaches and why Weber's deal is so complicated.
Rangers avoid arbitration with Michael Sauer, lock up Artem Anisimov
Jul 8, 2011, 1:23 PM EDT
The Rangers still have some free agent messes to clean up, but they simplified their summer by re-signing Michael Sauer and Artem Anisimov to two-year contract extensions.
Steven Stamkos' eventual signing in Tampa Bay doesn't deter Philly's flirtation with him
Jul 5, 2011, 1:33 PM EDT
While Steven Stamkos stays unsigned as a restricted free agent, it provides the fertile ground needed for speculation to rage that somehow the Philadelphia Flyers can get him away from Tampa Bay.
Semyon Varlamov's Russian agent bashes the Washington Capitals
Jun 29, 2011, 9:04 PM EDT
Semyon Varlamov's Russian agent won't say which KHL team his client is leaning toward, but he wasn't shy about bashing the Washington Capitals.
2011 free agents list: The restricted version
Jun 27, 2011, 10:22 PM EDTComments Off on 2011 free agents list: The restricted version
Earlier today, we shared the most relevant unrestricted free agents. Now let's take a look at the top restricted ones.
Flyers trade Darroll Powe to Minnesota for 2013 third round pick, clears room for re-signings
Jun 27, 2011, 5:16 PM EDT
Physical forward and penalty killer Darroll Powe is on the way to Minnesota in a deal that helps the Flyers clear more salary cap and roster space.
Semyon Varlamov's future with Capitals, NHL remains uncertain
Jun 26, 2011, 4:27 PM EDT
Things could change, but rumors indicate that pending restricted free agent Semyon Varlamov is unlikely to re-sign with the Washington Capitals.
Discussing the potential downsides to winning the Stanley Cup
Jun 12, 2011, 6:19 PM EDT
Obviously, winning the Stanley Cup is fantastic in the short term. That being said, there are actually some downsides to reaching the ultimate goal in hockey.
Should Winnipeg name their team the Jets? Andrew Ladd sees both sides of argument
Jun 9, 2011, 10:45 PM EDT
Should the Winnipeg team be named the Jets? Will he even play for whatever the team is called? Last season's Atlanta Thrashers captain Andrew Ladd discussed those issues today.
Buffalo Sabres sign Drew Stafford to four-year, $16M contract extension
Jun 3, 2011, 8:04 PM EDTComments Off on Buffalo Sabres sign Drew Stafford to four-year, $16M contract extension
The Sabres wrapped up pending restricted free agent Drew Stafford to a four-year deal reportedly worth $16 million today.
After breakthrough season, Tampa Bay Lightning face tough off-season questions
May 28, 2011, 8:00 AM EDT
The Lightning had a great run, but it could come at a price. GM Steve Yzerman has some big decisions to make as important players (including Steven Stamkos and Dwayne Roloson) approach restricted and unrestricted free agency.
Shea Weber, Predators seem confident they can reach compromise on new contract
May 11, 2011, 7:20 PM EDTComments Off on Shea Weber, Predators seem confident they can reach compromise on new contract
Many think the Predators might have trouble signing soon-to-be-restricted free agent defenseman Shea Weber, but both the team and player appear confident they'll figure something out.
Is Langenbrunner trade first of many to come in New Jersey?
Jan 7, 2011, 1:18 PM EDTComments Off on Is Langenbrunner trade first of many to come in New Jersey?
With Jamie Langenbrunner now off to Dallas, is this the first of many deals we see from the Devils before the trade deadline? Let's speculate the heck out of this.
Tampa Bay Lightning hope to open up contract extension discussions with Steven Stamkos
Nov 6, 2010, 1:15 PM EDTComments Off on Tampa Bay Lightning hope to open up contract extension discussions with Steven Stamkos
It shouldn't be a surprise that people are wondering about the Tampa Bay Lightning's contract extension discussions with Steven Stamkos considering his red-hot start. Click "Read More" for more details.
Flyers, Jeff Carter make progress in contract extension talks
Oct 28, 2010, 1:45 PM EDTComments Off on Flyers, Jeff Carter make progress in contract extension talks
Considering the fact that the two biggest potential 2011 free agents (Joe Thornton and Zdeno Chara) already signed lucrative extensions, the list narrows down to Brad Richards and mercurial forwards such as Alexander Semin. One of those mercurial forwards is Philadelphia Flyers sniper Jeff Carter, a player who can take over a game with his…
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The Message audio Bible is now available on Bible Gateway! Click to learn more.
denotes the whole creation in Rom. 8:39; Col. 1:15; Rev. 5:13; the whole human race in Mark 16:15; Rom. 8:19-22.
The living creatures in Ezek. 10:15, 17, are imaginary beings, symbols of the Divine attributes and operations.


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Challenge on Sessions' claim of daily murders by immigrants caught and released
WASHINGTON — Dallas Rep. Pete Sessions, chairman of the House Rules Committee, asserted last week that every day, a murder is committed by immigrants caught entering the country illegally, then released.
"Every day, all along border states, maybe other places, there are murders by people who have been arrested coming into this country, who have been released by the Obama administration, I believe in violation of the law, who are murdering Americans all over our cities. We hold the Democrat Party and the president personally accountable for this action," Sessions said. (Comments at the 23:30 mark of this video of a Rules Committee hearing Feb. 26).
The Washington Post Fact Checker looked at the claim and gave it four out of four Pinocchios, after Sessions was unable to provide evidence for his figures.
In an email to The Dallas Morning News today, Sessions press secretary Caroline Boothe said, "The Congressman was simply saying that the President's lawless immigration policies have created a severe problem and increased the likelihood that dangerous illegal aliens are being released and posing a threat to our communities."
There isn't nationwide data kept on murders committed by people who entered the country illegally.
The Post cited data from the Texas Department of Public Safety showing that between June 1, 2011, and Dec. 31, 2014, 795 non-U.S. citizens were arrested in Texas for homicide, and 336 were convicted. DPS spokesman Tom Vinger told Fact Checker that of those charged, 561 were in the country illegally. The breakdown for actual convictions was not immediately available.
But Sessions was talking about people who had been released by the Obama administration. That's a small fraction of the 11 million non-citizens living in the United States illegally. About 130,000 non-citizens were released in 2014.
In January, Sen. Check Grassley, R-Iowa, issued a report on crimes committed by the 36,007 immigrants in the U.S. illegally with criminal records who were released in 2013. About a thousand were convicted of a crime after their release, none for homicide.
Even if all 336 non-citizens convicted of homicide in Texas during the 43-month period covered by the DHS study were in the country illegally, that's far less than one murder per day. And Fact Checker estimated that 239 of those convicted of murder were in the country illegally.
Sessions, through his aide, called the problem significant even if the magnitude wasn't precise.
"As stated by the Washington Post article, an estimated 239 illegal aliens were convicted of murder over a 43-month period," Boothe said. "That is not an insignificant number and could be lessened if the Administration enforced our rule of law."