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Independent Political Labour League
The Independent Political Labour League (IPLL) was a small New Zealand political party. It was the second organised political party to win a seat in the House of Representatives, and was a forerunner of the modern Labour Party.
The IPLL was the product of a gradual move towards an independent working-class political vehicle. Previously, most workers supported the powerful Liberal Party, which had dominated Parliament since its creation. Eventually, however, the pace of reform began to slow, and calls arose for an independent workers' party. In 1904, the annual conference of Trades and Labour Councils called for the formation of a new organisation. This party would be focused solely on workers, unlike the Liberal Party, but would be committed to change through reform, unlike the revolution-minded Socialist Party. A constitution was drawn up in late 1904, and the first conference was held in early 1905, with John Rigg elected as the first president.[1] At the conference, it was claimed that the new organisation had over a thousand members.
Electoral history[edit]
Initially, the IPLL did not perform well. In the 1905 elections, the party stood 11 candidates: two in Auckland, four in Wellington, three in Christchurch, and one each in the Egmont and Invercargill electorates.[2] None were elected, and all but one failed to win enough votes to reclaim their deposits.[3][4] The party also failed in its attempts to recruit from among the more sympathetic Liberal MPs.
In the 1908 election, however, one IPLL candidate was elected in the Wellington East electorate on the second ballot. The Liberal vote was split by two Liberal Party candidates, and both Liberal candidates were eliminated in the first ballot. This left the IPLL candidate, David McLaren, face a conservative candidate and with many Liberal voters transferring their allegiance to McLaren, he won the second ballot.[5][6] This was the first time that any organised political party other than the Liberals had won a seat; the conservative opposition was still disorganised.
Position in wider Labour politics[edit]
The IPLL itself, however, was increasingly failing. Internal disputes, such as whether the party should work with or against the Liberals, created tension, and the party was generally disorganised. In 1910, the remnants of the IPLL were relaunched as a new organisation, known as the Labour Party (not to be confused with the modern party of the same name). Eventually, this Labour Party joined with several independent groups to create the United Labour Party, which then merged with the Socialist Party to form the Social Democratic Party. The Social Democrats, along with various members of the United Labour Party who had rejected the previous merger, eventually formed the basis of the modern Labour Party.
- ^ "Independent Political Labour League". The Evening Post LXIX (118). 20 May 1905. p. 2. Retrieved 24 August 2011.
- ^ Gustafson 1980, p. 18.
- ^ "The Recent Election - Men who Lost Money". Wairarapa Daily Times XXIX (8327). 19 December 1905. p. 7. Retrieved 24 August 2011.
- ^ "Results of the Polls". Ashburton Guardian xxii (6742). 7 December 1905. p. 2. Retrieved 24 August 2011.
- ^ Gustafson 1980, p. 19.
- ^ "The General Election, 1908". National Library. 1909. pp. 13, 31. Retrieved 2 February 2014.
- Gustafson, Barry (1980). Labour's path to political independence: The Origins and Establishment of the New Zealand Labour Party, 1900–19. Auckland, New Zealand: Auckland University Press. ISBN 0-19-647986-X.

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A great use of an Old Building, the museum houses artwork and the tools used to produce them, It may not have the big names, however, personally I found it quite interesting and...
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A great use of an Old Building, the museum houses artwork and the tools used to produce them, It may not have the big names, however, personally I found it quite interesting and entertaining.
You can easily miss the entrance to this museum but it is right next to the Cathedral. The art is mostly religious but I found it frustrating that there were no descriptions in English! After reading a previous review about not missing the prison, we didn't even know there was a prison to see, so yes - we missed it!...
Tucked away behind the Cathedral is the Art Museum which really traces the development of local art from the Visigoths to the present day. The best of this is alter pieces from various churches but there is an interesting range from Spanish artists you are likely to be less familiar with.
I managed to arrive at a time when the museum was almost empty. I took a quick look at the displays though 5 floors, and then settled on the 4th floor to prioritize where I wanted to spend time. One item that piqued my attention was the room called "Discovery point" on the 5th floor. I popped my head into...
I am very interested in art but this gallery was almost totally of religious art- I do not know if the artists of Girona only did religious works.
Lovely building with too many stairs, though there was a lift which we used to go to the top then worked our way down. The exhibits are arranged historically though so if you do that then you're working your way backwards. The first 3 floors are mostly religeous works, carvings and paintings that you would expect to find in churches...
I think this art museum would be perfect for someone very interested in art and perhaps religious art. I went with friends who loved it. I dont know if Girona, Spain is the place to see amazing masterpieces
Sorry, apart from the moderns I don't find Spain a great place to see art. Lots here in the "curiosity" category rather than "masterpiece".
if you like religious art, this is the best place you can go in Girona
The Girona Art Museum is just by the Cathedral in Barri Vell and is absolutely worth a visit. The museum itself is charmingly restored to house a collection of Gothic sculptures, paintings and other objects that help tell the story of Girona and Catalunya. The staff are helpful and welcoming in this little gem of a museum, go and enjoy...
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Publications (17)69.12 Total impact
Article: Hypogammaglobulinemia in newly diagnosed chronic lymphocytic leukemia: Natural history, clinical correlates, and outcomes: Hypogammaglobulinemia in CLL[Show abstract] [Hide abstract]
ABSTRACT: Although hypogammaglobulinemia is a well recognized complication in patients with chronic lymphocytic leukemia (CLL), its prevalence at the time of CLL diagnosis, and association with novel prognostic markers and clinical outcome is not well understood. All patients at the Mayo Clinic between January 1999 and July 2013 who had newly diagnosed CLL and had a baseline assessment of serum immunoglobulin G (IgG) were included. The relation between hypogammaglobulinemia at diagnosis and the novel prognostic parameters time to first treatment (TFT) and overall survival (OS) were evaluated. Of 1485 patients who met the eligibility criteria, 382 (26%) had hypogammaglobulinemia (median IgG, 624 mg/dL), whereas the remaining 1103 patients (74%) had normal serum IgG levels (median IgG, 1040 mg/dL). Patients who had hypogammaglobulinemia at diagnosis were more likely to have advanced Rai stage (III-IV; P = .001) and higher expression of CD49d (P < .001) compared with patients who had normal IgG levels. Although the median TFT for patients who had hypogammaglobulinemia was shorter compared with that for patients who had normal IgG levels (3.8 years vs 7.4 years; P < .001), on multivariable analysis, there was no difference in OS between these 2 groups (12.8 years vs 11.3 years, respectively; P = .73). Of 1103 patients who had CLL with normal IgG levels at diagnosis and who did not receive CLL therapy, the risk of acquired hypogammaglobulinemia was 11% at 5 years and 23% at 10 years. Hypogammaglobulinemia is present in 25% of patients with newly diagnosed CLL. Approximately 25% of patients who have CLL with normal IgG levels at diagnosis will subsequently develop hypogammaglobulinemia on long-term follow-up. The presence of hypogammaglobulinemia does not appear to impact overall survival. Cancer 2015;000:000-000. © 2015 American Cancer Society. © 2015 American Cancer Society.Cancer 04/2015; DOI:10.1002/cncr.29438 · 4.90 Impact Factor
Article: Impact of Ibrutinib and Idelalisib on the Pharmaceutical Cost of Treating Chronic Lymphocytic Leukemia at the Individual and Societal Levels[Show abstract] [Hide abstract]
ABSTRACT: To evaluate the impact of approval of ibrutinib and idelalisib on pharmaceutical costs in the treatment of chronic lymphocytic leukemia (CLL) at the societal level and assess individual out-of-pocket costs under Medicare Part D. Average wholesale price of commonly used CLL treatment regimens was ascertained from national registries. Using the population of Olmsted County, Minnesota, we identified the proportion of patients with newly diagnosed CLL who experience progression to the point of requiring treatment. Using these data, total pharmaceutical cost over a 10-year period after diagnosis was estimated for a hypothetic cohort of 100 newly diagnosed patients under three scenarios: before approval of ibrutinib and idelalisib (historical scenario), after approval of ibrutinib and idelalisib as salvage therapy (current scenarios A and B), and assuming use of ibrutinib as first-line treatment (potential future scenario). Estimated 10-year pharmaceutical costs for 100 newly diagnosed patients were as follows: $4,565,929 (approximately $45,659 per newly diagnosed patient and $157,446 per treated patient) for the historical scenario, $7,794,843 (approximately $77,948 per newly diagnosed patient and $268,788 per treated patient) for current scenario A, $6,309,162 (approximately $63,092 per newly diagnosed patient and $217,557 per treated patient) for current scenario B, and $16,414,055 (approximately $164,141 per newly diagnosed patient and $566,002 per treated patient) for the potential future scenario. Total out-of-pocket cost for 100 patients with newly diagnosed CLL under Medicare Part D increased from $9,426 under the historical scenario (approximately $325 per treated patient) to $363,830 and $255,051 under current scenarios A and B (approximately $8,800 to $12,500 per treated patient) and to $1,031,367 (approximately $35,564 per treated patient) under the future scenario. Although ibrutinib and idelalisib are profound treatment advances, they will dramatically increase individual out-of-pocket and societal costs of caring for patients with CLL. These cost considerations may undermine the potential promise of these agents by limiting access and reducing adherence. Copyright © 2015 by American Society of Clinical Oncology.Journal of Oncology Practice 03/2015; 11(3). DOI:10.1200/JOP.2014.002469
- Blood 03/2015; 125(10):1676-8. DOI:10.1182/blood-2014-12-610782 · 10.43 Impact Factor
Article: Hodgkin transformation of chronic lymphocytic leukemia: Incidence, outcomes, and comparison to de novo Hodgkin lymphoma: Hodgkin transformation of CLL[Show abstract] [Hide abstract]
ABSTRACT: Although transformation to Hodgkin lymphoma (HL) is a recognized complication in patients with chronic lymphocytic leukemia (CLL), its incidence, clinical characteristics and outcomes are not well defined.We used the Mayo Clinic CLL and Lymphoma Databases to identify CLL patients who developed biopsy-proven HL (CLL/HL) on follow-up, as well as cases of de novo HL (i.e., without prior CLL). Among 3887 CLL patients seen at Mayo Clinic from January 1995 through August 2011, 26 (0.7%) developed HL. In a nested cohort of 2465 newly diagnosed CLL patients followed prospectively, the incidence of HL was 0.05%/year (10 year risk=0.5%). The median overall survival (OS) from date of HL diagnosis in patients with CLL/HL was 3.9 years compared to not reached for de novo HL patients (n=709) seen during the same time interval (p<0.001). The shorter OS of CLL/HL patients persisted after adjusting for differences in age and Ann Arbor stage of disease. The International Prognostic score (IPS) developed for de novo HL stratified prognosis among CLL/HL patients with median survival of not reached, 6.2 years, 2.4 years and 0.3 years (p=0.006) for those with IPS scores of ≤2, 3, 4 and ≥5, respectively. In summary, approximately 1 of every 200 CLL patients will develop HL within 10 years. Survival after HL diagnosis in patients with CLL is shorter than de novo HL patients. The IPS for de novo HL may be useful for stratifying survival in CLL/HL patients. This article is protected by copyright. All rights reserved.American Journal of Hematology 01/2015; 90(4). DOI:10.1002/ajh.23939 · 3.48 Impact Factor
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ABSTRACT: Richter syndrome (RS) is defined as the transformation of chronic lymphocytic leukemia (CLL) to a more aggressive B-cell lymphoma, most commonly diffuse large B-cell lymphoma. Approximately 5 - 10 % of CLL patients develop this complication during long-term follow-up. Traditional risk factors for future RS include clinical (advanced Rai stage), biological (ZAP-70, CD38, CD49d) and genetic (del17p, del11q) characteristics at the time of CLL diagnosis. The impact of CLL therapy (purine-nucleoside analogue and/or alkylator-based chemoimmunotherapy and kinase inhibitor therapy) on the risk of RS remains controversial. Both heritable (germline) and acquired (somatic) genetic mutations contribute to risk of RS. Germline polymorphisms in genes related to CD38, LRF4, and BCL-2 have been implicated in the development of RS. Somatic mutations contributing to the development of RS include TP53 disruption, c-myc activation, CDKN2A loss and NOTCH1 mutations. This review summarizes recent advances in our understanding of the biological and genetic factors contributing to RS in CLL patients.Current Hematologic Malignancy Reports 09/2014; 9(3). DOI:10.1007/s11899-014-0223-4 · 2.29 Impact Factor
Article: Oral capecitabine to prevent recurrent cutaneous squamous cell carcinoma in a lung transplant recipientInternational journal of dermatology 09/2014; DOI:10.1111/ijd.12682 · 1.23 Impact Factor
- Clinical Lymphoma, Myeloma and Leukemia 09/2014; 14:S132-S133. DOI:10.1016/j.clml.2014.06.061 · 2.02 Impact Factor
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ABSTRACT: Objective To describe the prognostic factors and outcomes of adults with hemophagocytic lymphohistiocytosis (HLH), a rare disorder caused by pathologic activation of the immune system. Patients and Methods The study population consisted of a consecutive cohort of adult (age ≥18 years) patients treated at Mayo Clinic in Rochester, Minnesota, from January 1, 1996, through December 31, 2011, in whom a diagnosis of HLH was suspected and subsequently confirmed by retrospective review using the HLH-04 diagnostic criteria. Results Of 250 adult patients suspected of having HLH, 62 met the HLH-04 diagnostic criteria and were included in the final analysis. The median age was 49 years (range, 18-87 years), and 42 (68%) were male. The underlying cause of HLH was malignant tumor in 32 patients (52%), infection in 21 patients (34%), autoimmune disorder in 5 patients (8%), and idiopathic disease in 4 patients (6%). After a median follow-up of 42 months, 41 patients (66%) had died. The median overall survival of the entire cohort was 2.1 months. The median overall survival of patients with tumor–associated HLH was 1.4 months compared with 22.8 months for patients with non-tumor–associated HLH (P=.01). The presence of a malignant tumor and hypoalbuminemia were significant predictors of inferior survival on multivariate analysis. Conclusion In this large series of adults with secondary HLH treated at a single tertiary care center, patients with low serum albumin levels and tumor–associated HLH had a markedly worse survival. Hemophagocytic lymphohistiocytosis remains elusive and challenging to clinicians who must maintain a high index of suspicion. The recent discovery of several novel diagnostic and therapeutic modalities may improve outcomes of adult patients with HLH.Mayo Clinic Proceedings 04/2014; DOI:10.1016/j.mayocp.2013.12.012 · 5.81 Impact Factor
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ABSTRACT: Chronic myelomonocytic leukaemia (CMML) is a clonal haematopoietic stem cell disorder with myelodysplastic and myeloproliferative overlap features, and an inherent tendency to transform to acute myeloid leukaemia. Approximately 30% of patients present with clonal cytogenetic abnormalities, while almost 90% have molecular aberrations involving epigenetic regulation, the spliceosome component machinery, tumour suppressor genes and transcription factors/regulators. Numerous prognostic models exist for CMML, with more recent models incorporating prognostic mutations, such as those involving ASXL1. Other variables that seem to consistently affect outcomes include the degree of leucocytosis/monocytosis, anaemia and thrombocytopenia. Allogeneic stem cell transplant remains the only curative option for CMML, while hypomethylating agents can be used for transplant-ineligible patients or those without suitable stem cell sources. Targeting biological pathways activated in CMML offers potential hope for more effective and less toxic therapies.British Journal of Haematology 01/2014; DOI:10.1111/bjh.12756 · 4.96 Impact Factor
Article: Secondary Hemophagocytic Syndrome Associated with Richter's Transformation in Chronic Lymphocytic Leukemia[Show abstract] [Hide abstract]
ABSTRACT: Hemophagocytic syndrome (HPS) is an extremely rare condition arising from the overactivation of one's own immune system. It results in excessive inflammation and tissue destruction. Prompt initiation of treatment is warranted in either scenario in order to decrease mortality. Most cases are triggered by infectious agents, malignancy, or drugs. We describe the first case of a CLL patient presenting with HPS due to acquisition of EBV-related large cell lymphoma in the setting of profound immunodeficiency.01/2014; 2014:287479. DOI:10.1155/2014/287479
Article: How we treat Richter syndrome[Show abstract] [Hide abstract]
ABSTRACT: Richter syndrome (RS) is defined as the transformation of chronic lymphocytic leukemia (CLL) into an aggressive lymphoma, most commonly diffuse large B-cell lymphoma (DLBCL). RS occurs in approximately 2-10% of CLL patients during the course of their disease, with a transformation rate of 0.5-1% per year. A combination of germline genetic characteristics, clinical features (e.g. advanced Rai stage), biologic (ZAP-70+, CD38+ and CD49d+) and somatic genetic (del17p13.1 or del11q23.1) characteristics of CLL B-cells, and certain CLL therapies are associated with higher risk of RS. Recent studies have also identified the crucial role of CDKN2A loss, TP53 disruption, C-MYC activation, and NOTCH1 mutations in the transformation from CLL to RS. An excisional lymph node biopsy is considered the gold standard for diagnosis of RS where (18)F-fluorodeoxyglucose positron emission tomography (PET) scan can help inform the optimal site for biopsy. Approximately 80% of DLBCL cases in patients with CLL are clonally related to the underlying CLL and the median survival for these patients is approximately 1 year. In contrast, the remaining 20% of patients have a clonally unrelated DLBCL and have a prognosis similar to that of de novo DLBCL. For patients with clonally related DLBCL, induction therapy with either an anthracycline- or platinum-based regimen is the standard approach. Post remission stem cell transplantation should be considered for appropriate patients. This article summarizes our approach to the clinical management of CLL patients who develop RS.Blood 01/2014; 123(11). DOI:10.1182/blood-2013-11-516229 · 10.43 Impact Factor
Article: ANNUAL CLINICAL UPDATES IN HEMATOLOGICAL MALIGNANCIES: A CONTINUING MEDICAL EDUCATION SERIES Chronic myelomonocytic leukemia: 2013 update on diagnosis, risk stratification, and management[Show abstract] [Hide abstract]
ABSTRACT: Disease overview: Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder that is classified as a myelodysplastic/myeloproliferative neoplasm by the 2008 World Health Organization classification of hematopoietic tumors. It is characterized by absolute monocytosis (>1 x 10(9)/L) in the peripheral blood that persists for at least 3 months. Diagnosis: The diagnosis of CMML rests on a combination of morphologic, histopathologic and chromosomal abnormalities in the bone marrow. It is important to exclude other myeloproliferative neoplasms and infectious/autoimmune conditions that can cause monocytosis. Risk stratification: Several CMML-specific prognostic models incorporating novel mutations have been recently reported. The Mayo prognostic model classified CMML patients into three risk groups based on: increased absolute monocyte count, presence of circulating blasts, hemoglobin <10 gm/dL and platelets <100 x 10(9)/L. The median survival was 32 months, 18.5 months and 10 months in the low, intermediate, and high-risk groups, respectively. The Groupe Francophone des (GFM) score segregated CMML patients into three risk groups based on: age >65 years, WBC >15 x 10(9)/L, anemia, platelets <100 x10(9)/L, and ASXL1 mutation status. After a median follow-up of 2.5 years, survival ranged from not reached in the low-risk group to 14.4 months in the high-risk group. Risk-adapted therapy: The Food and Drug Administration has approved azacitidine and decitabine for the treatment of patients with CMML. An allogeneic stem cell transplant can potentially offer a curative option to a subset of CMML patients. It is hoped that with the discovery of several novel mutations, targeted therapies will become available in the near future. Am. J. Heamtol. 88: 968-974, 2013. (C) 2013 Wiley Periodicals, Inc.American Journal of Hematology 11/2013; 88(11):968-974. · 3.48 Impact Factor
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ABSTRACT: Monoclonal B-cell lymphocytosis (MBL) is a clonal B-cell disorder characterized by less than 5 × 109/L B lympho- cytes in the peripheral blood, with a characteristic immunophe- notype and no lymphadenopathy or organomegaly. The vast majority of MBL cases express the immunophenotype of chronic lymphocytic leukemia (CLL; CLL-like MBL), although non-CLL MBL also exists. CLL-like MBL, which is the focus of this review, is divided into low-count MBL (median B-cell count: 0.001 × 109/L, typically identified in population-based screening studies using highly sensitive flow cytometry assays) and high-count MBL (clinical MBL, median B-cell count: 2.9 × 109/L, typically identi- fied during the workup of low-level lymphocytosis). Low-count MBL has an exceedingly small risk of progression to CLL, and these patients do not require any specific follow-up. In contrast, patients with high-count MBL have a 1% to 2% per year risk of progression to CLL requiring therapy, as well as a higher risk of infectious complications and secondary malignancies. Although the overall survival of high-count MBL patients collectively is similar to the age- and sex-matched general population, 5-year survival for high-count MBL with higher-risk biologic parameters appears to be slightly lower than that of the general population. This review summarizes key concepts in the classification, diag- nosis, and biology of CLL-like MBL and addresses several impor- tant issues in clinical management. [Editor's Note: Corrections were made to this article on February 12, 2014.].Clinical advances in hematology & oncology: H&O 11/2013; 11(11):720-729.
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ABSTRACT: Nuclear protein in testis (NUT) midline carcinoma (NMC) is a poorly differentiated squamous cell carcinoma that is characterized by a balanced translocation between chromosomes 15 and 19 [t(15;19)(q14;p13.1)]. This genetic aberration results in the fusion of the NUT gene on chromosome 15 to the bromodomain containing 4 (BRD4) gene on chromosome 19. The resultant BRD4-NUT fusion oncogene leads to global hypoacetylation and transcriptional repression of genes required for differentiation." Although it was first reported in 1991 by Kubonishi et al., awareness of this condition remains low and the diagnosis is overlooked initially in a number of patients. A 36-year-old man complained of cough and right-sided chest pain for 3 weeks before presentation. Imaging studies revealed a right hilar mass, and a bronchoscopic biopsy was consistent with an aggressive poorly differentiated neoplasm. A combination of cisplatin, ifosfamide, and etoposide was administered for two cycles without any improvement. A repeat core biopsy showed focal squamous differentiation; and given the clinical presentation along with the histologic features, NMC was considered in the differential diagnosis. Immunohistochemical staining for NUT was positive, and dual-color break-apart fluorescence in situ hybridization demonstrated BRD4-NUT rearrangement, thereby confirming a diagnosis of NMC. Our patient was subsequently enrolled on a phase 1 clinical trial of a novel, orally bioavailable bromodomain and extra terminal inhibitor, GSK525762 (NCT01587703). This report illustrates the challenges in diagnosing this rare malignancy, and highlights new treatment options for these patients.Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer 10/2013; 8(10):1335-8. DOI:10.1097/JTO.0b013e3182a00f41 · 5.80 Impact Factor
Article: Chronic lymphocytic leukemia in young (less than 55 years) patients: a comprehensive analysis of prognostic factors and outcomes.[Show abstract] [Hide abstract]
ABSTRACT: The clinical characteristics and outcomes of younger (≤55 years) patients with chronic lymphocytic leukemia in the era of modern prognostic biomarkers and chemoimmunotherapy are not well understood. Baseline characteristics and outcomes of patients with chronic lymphocytic leukemia ≤55 years who were seen at Mayo Clinic between 1/1995 and 4/2012 were compared with those >55 years. Overall survival of patients ≤55 was compared to age- and sex-matched normal population. The characteristics of 844 newly diagnosed chronic lymphocytic leukemia patients ≤55 years (median, 50 years) were compared to 2324 patients >55 years (median, 67 years). Younger patients were more likely to be Rai stage I or II (p<0.0001), IGHV unmutated (p=0.002) and ZAP-70 positive (p=0.009). These differences became more pronounced when ≤55 age group was sub-stratified into age ≤45, 46-50 and 51-55 years. After a median follow-up of 5.5 years, 426 (51%) patients ≤55 received treatment, and 192 (23%) had died. Patients ≤55 had a shorter time to first treatment (4.0 years vs. 5.2 years; p=0.001) but longer survival (12.5 years vs. 9.5 years; p<0.0001) compared to patients >55 yrs. However, patients ≤55 had significantly shorter survival than age- and sex-matched normal population (12.5 years vs. not reached; p<0.0001). Our study is the first comprehensive analysis of younger chronic lymphocytic leukemia patients in the modern era. Adverse prognostic markers appear more common among young patients. Although the survival of young chronic lymphocytic leukemia patients is longer than those >55, their survival relative to the age- and sex-matched normal population is profoundly shortened.Haematologica 08/2013; DOI:10.3324/haematol.2013.086066 · 5.87 Impact Factor
Article: Diffuse large B-cell lymphoma (Richter syndrome) in patients with chronic lymphocytic leukaemia (CLL): a cohort study of newly diagnosed patients[Show abstract] [Hide abstract]
ABSTRACT: Nearly all information about patients with chronic lymphocytic leukaemia (CLL) who develop diffuse large B-cell lymphoma [Richter syndrome (RS)] is derived from retrospective case series or patients treated on clinical trials. We used the Mayo Clinic CLL Database to identify patients with newly diagnosed CLL between January 2000 and July 2011. Individuals who developed biopsy-proven RS during follow-up were identified. After a median follow-up of 4 years, 37/1641 (2·3%) CLL patients developed RS. The rate of RS was approximately 0·5%/year. Risk of RS was associated with advanced Rai stage at diagnosis (P < 0·001), high-risk genetic abnormalitites on fluorescence in situ hybridization (P < 0·0001), unmutated IGHV (P = 0·003), and expression of ZAP70 (P = 0·02) and CD38 (P = 0·001). The rate of RS doubled in patients after treatment for CLL (1%/year). Stereotyped B-cell receptors (odds-ratio = 4·2; P = 0·01) but not IGHV4-39 family usage was associated with increased risk of RS. Treatment with combination of purine analogues and alkylating agents increased the risk of RS three-fold (odds-ratio = 3·26, P = 0·0003). Median survival after RS diagnosis was 2·1 years. The RS prognosis score stratified patients into three risk groups with median survivals of 0·5 years, 2·1 years and not reached. Both underlying characteristics of the CLL clone and subsequent CLL therapy influence the risk of RS. Survival after RS remains poor and new therapies are needed.British Journal of Haematology 07/2013; 162(6). DOI:10.1111/bjh.12458 · 4.96 Impact Factor
Article: Chronic myelomonocytic leukemia: 2012 update on diagnosis, risk stratification, and management[Show abstract] [Hide abstract]
ABSTRACT: DISEASE OVERVIEW: Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder that is classified as a myelodysplastic/myeloproliferative neoplasm by the 2008 World Health Organization classification of hematopoietic tumors. It is characterized by absolute monocytosis (>1 × 10(9) L(-1) ) in the peripheral blood that persists for at least 3 months. Patients may present with symptoms related to cytopenias and/or an underlying hypercatabolic state with drenching night sweats, splenomegaly, and weight loss. DIAGNOSIS: The diagnosis of CMML rests on a combination of morphologic, histopathologic, and chromosomal abnormalities in the bone marrow, after careful exclusion of other conditions (both malignant and nonmalignant) that can cause monocytosis. Numerous molecular abnormalities have been recently recognized in patients with CMML-unfortunately, no single pathognomonic finding specific to CMML has been identified thus far. RISK STRATIFICATION: The International Prognostic Scoring System for myelodysplastic syndrome (MDS) cannot be used to risk stratify patients with CMML because this model excluded patients with a leukocyte count >12 × 10(9) L(-1) . Other risk stratification models such as the MD Anderson prognostic score and Dusseldorf score have been published. In the only model that took karyotype into account, bone marrow blasts ≥ 10%, leukocyte count ≥ 13 × 10(9) L(-1) , hemoglobin < 10 g/dL, platelet count < 100 × 10(9) L(-1) , and presence of trisomy 8, abnormalities of chromosome 7, or complex karyotype were found to be independent predictors of adverse survival. RISK-ADAPTED THERAPY: The Food and Drug Administration has approved azacitidine and decitabine for the treatment of patients with CMML based on two pivotal trials in MDS. Novel classes of agents including immunomodulatory drugs, nucleoside analogs, and small-molecule tyrosine kinase inhibitors are being investigated in the treatment of CMML. With the advent of reduced intensity conditioning, an allogeneic stem cell transplant has also become a viable option for a subset of patients.American Journal of Hematology 06/2012; 87(6):610-9. DOI:10.1002/ajh.23203 · 3.48 Impact Factor
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Mayo Clinic - ScottsdaleScottsdale, Arizona, United States
Mayo Clinic - Rochester
Рочестер, Minnesota, United States
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I'm from Finland, I like to travel, see new places and meet people from other places and cultures. Other interests include food (cooking also) and wine, friends, knitting, reading etc etc. I lived (studied or worked) in a few different countries but have been living and working in Helsinki for about seven years now.
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As of Version 10, most of the functionality of the Combinatorica package is built into the Wolfram System. >>
gives the fewest number of colors necessary to color each edge of graph g, so that no two edges incident on the same vertex have the same color.
- To use , you first need to load the Combinatorica Package using Needs["Combinatorica`"].
- Computation on Graphs
- Discrete Mathematics
- Graph Construction & Representation
- Graph Operations and Modifications
- Graph Properties
- Graph Properties
- Graph Properties & Measurements
- Graphs and Matrices
- Graphs & Networks
- Graph Visualization
- Mathematical Data Formats
- Statistical Analysis
- Social Network Analysis


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hog_heaven, on 02 August 2014 - 08:27 PM, said:
I am on a project at work that keeps me from the regular internet (government crap). And I am also working at GNC in the evenings/weekends. I haven't been on any internet except to pay bills lately.
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hog_heaven, on 02 August 2014 - 08:27 PM, said:
possumslayer, on 03 August 2014 - 12:01 AM, said:
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It seems like root and alias do the same things by definition, but for some reason when I use root, I get a 404, but it works fine when I use alias. Any ideas?
Take the 2-minute tour ×
Super User is a question and answer site for computer enthusiasts and power users. It's 100% free, no registration required.
From what I can tell, this is how they differ.


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What is the reason for removing class attribute from
li added by wp_list_pages? (Line 50)
What is the reason for removing class attribute from
li added by wp_list_pages? (Line 50)
The wp_list_pages function is intended to be used outside of the content area, in the header, footer or sidebar. Many themes use these classes added by wp_list_pages to apply styling for any one or all of those areas. Since this plugin puts the unordered list in the content, it should not take on such styling. In our testing, with some themes it made it look like the sidebar was accidentally placed in the page content. Removing the class made the unordered list look like other unordered lists in the page content.
Is there a reason you want those specific classes applied?
We came across an instance to add borders for some selected items in the list, when sitemap is used as content. Removing class makes sense. What do you think about replacing it with class="sitemap_class1 sitemap_class2..."?
Btw, this is a simple yet powerful shortcode.
Thank you
I think it's a good idea to pass in the class in the shortcode. I've added it to my TODO list.
In the short term, you can easily wrap the list in a span or a div with a class or ID to style all the children elements. e.g.
[html-sitemap]
#page_list ul {
#page_list ul li {
yes a simple "class" or "id" identifier in the shortcode would be awesome. Even if you injected your own class upon using the ul. like

Yes, class and id are good ideas and they are on my TODO list.
This topic has been closed to new replies.


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Channa Masala
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Channa Cabbage Recipe Cooking Show
Channa Cabbage Recipe is a fine recipe which is a simple to cook and also easy to have with other recipes so try this out.
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Channa Masala Recipe Cooking Show
Here is a recipe for Channa Masala, it's an easy dish to make and vegetarian too.
Added: 2040 days ago by
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How to make Channa Masala - a delicious recipe that you'll love
Here is a great recipe for Channa Masala. This is one of the most popular dishes in the world. It's vegetarian, tasty and pretty simple to make. Here we show you how
Added: 2037 days ago by
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Kala Channa Recipe Cooking Show
Kala Channa is a delicious recipe made out of channa and other ingredients try this out.
Added: 1916 days ago by
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By Catholic Online (NEWS CONSORTIUM)
12/18/2013 (1 year ago)
Catholic Online (www.catholic.org)
After weeks of violence, government forces are now in charge of the situation in South Sudan. Flights have since resumed at Juba International Airport. Fighting has left 500 people dead, according to the Ministry of Foreign Affairs. Many officials warn that the world's newest nation that the situation still remains volatile.
By Catholic Online (NEWS CONSORTIUM)
Catholic Online (www.catholic.org)
12/18/2013 (1 year ago)
Published in Africa
Keywords: South Sudan, coup attempt, United Nations
LOS ANGELES, CA (Catholic Online) - The United Nations acting spokesman on South Sudan, Joseph Contreras told reporters that "It is a very, very fluid situation, so I don't think the country is out of the woods yet."
The South Sudanese government in the meantime said that its forces are in "absolute control of the situation" and that a coup attempt over the weekend was not based on ethnic divisions but rather on "the power ambitions" of the coup plotters.
In addition to the hundreds dead , 800 people have been wounded in the violence. Information Minister Michael Makuei Lueth says that bodies are still being found in forests. Many of those who were wounded are dying in hospitals.
Deadly clashes started Sunday night. South Sudan's President Salva Kiir said his forces foiled a coup attempt.
Between 15,000 and 20,000 people have taken shelter in the organization's compounds in the capital, Juba.
"There are many, many people who have run away, and there are also people who have been killed," one woman who fled the fighting said. "Now there is a woman who has a baby who was shot in the back and died."
Makuei says that the situation in Juba had returned to normal, with people returning to work, flights resuming and government offices opening. It is reported that rebels who have clashed with government forces had moved closer to the Nile River.
Makuei disputed the suggestion that ethnic tensions ratcheted up the violence. He reiterated that people from different states and tribes rose up against the government, which is now fighting back.
Ten people have been reportedly arrested in connection with the foiled coup. Five others are still at large, according to an official government Web site.
The United Nations' Secretary-General Ban Ki-moon spoke to leaders, expressing his concern about the fighting, urging "all parties to cease hostilities immediately" and called on the government to "exercise restraint in the management of the situation and to guarantee the protection of all civilians regardless of their ethnicities."
There has been an influx of wounded to Juba's two main hospitals. The International Committee of the Red Cross has said it is providing hospitals with support, such as wound-dressing materials, to cope with the heavy influx of patients. More than 300 people have been admitted to Juba Teaching Hospital and Juba Military Hospital over the past two days.
"We know there are more people who need care, but they are having difficulty reaching healthcare facilities because of the security situation and the lack of available transportation," Felicity Gapes, an ICRC delegate leading the medical response on the ground said in a statement.
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By Talia Ramos (NEWS CONSORTIUM)
Last Friday, a very tragic event happened at the Imperial Marhaba Beach Hotel in Sousse, Tunisia. A 23-year-old man dressed just like any other tourist, passed by the hotel, and shot foreigners with a Kalashnikov rifle, he had hidden under his umbrella. Thirty-nine ... continue reading
By Talia Ramos (NEWS CONSORTIUM)
Italian authorities have given the Catholic priests permission to "exorcise," or do counter-magic to Nigerian migrant girls who have been "under a voodoo spell to work as prostitutes." There are around 25,000 women from Nigeria who have been brought to Italy by ... continue reading
By Linky C. (NEWS CONSORTIUM)
Two hundred and nineteen girls kidnapped by Boko Haram, from the boarding school in Chibok, Nigeria, are believed to have been brainwashed and now working for the Boko Haram, as reported by Amnesty International. The girls who were taken from their school grounds, a ... continue reading
By Catholic Online (NEWS CONSORTIUM)
Thirty-seven people have been killed - and at least another 36 were injured in a terrorist shooting spree in the beachside town of Sousse in Tunisia. At least five people from the United Kingdom are listed as among the dead. The believed gunman in the massacre, ... continue reading
By Catholic Online (NEWS CONSORTIUM)
It's a satanic practice once thought consigned to a very, very dark age - but it is increasing in frequency throughout the African nation of Uganda. "Witch doctors" are abducting and killing schoolchildren to use their body parts in malefic rituals. It is ... continue reading
By Katy Migiro, Thomson Reuters Foundation
Men in war-torn Somalia suffer high rates of drug addiction, divorce and mental illness, researchers said, urging donors to do more to support men and strengthen families. NAIROBI (Thomson Reuters Foundation) - In Somali culture, men are expected to provide all ... continue reading
By Atarah Haely (NEWS CONSORTIUM)
As Katherine Chappell, the American tourist attacked and killed by a lion during an African safari tour, was being attacked, the staff of the park hesitated to treat Chappell and the ambulance took a long time to arrive, according to Pierre Potgieter, the tour guide. ... continue reading
By Obianuju Ekeocha
In the last few years, we have woken up to the indescribable horror and terror of Boko Haram. And every one of us will agree that their actions and operations are merciless, viscous and violent beyond words. And so we pray for an end to the death and destruction ... continue reading
By Stella Dawson, Thomson Reuters Foundation
Multinational companies deprive African governments of $11 billion in taxes each year, and G7 world leaders should set up a new global body to regulate corporate taxation, Oxfam International said on Monday. WASHINGTON (Thomson Reuters Foundation) - By shifting ... continue reading
By Nikky Andres (NEWS CONSORTIUM)
When one 22 year old tourist from the United States planned her trip to South Africa, being mauled and attacked by a big angry cat was definitely not part of her itinerary. Unfortunately for this young woman, it turned out this trip would be her last. MUNTINLUPA, ... continue reading


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Sotira Restaurants
Ploumin: traditional homemade cypriot food
A great restaurant away from the beaten track. This was recommended by one of the waiters in our hotel (Grecian Park Hotel). The restaurant was in a court yard. The menu was written in English and Greek. The owner and staff were extremely friendly. The owner's mother was rolling cheese croquettes, whilst we were eating. There is no closing time; they close when the customers have finished eating and drinking.
Favorite Dish: Don't eat before you go. We all had the classic meze including a vegetarian option. We were all extremely full and the food kept coming. We drank two bottles of very good Cypriot red wine, Cypriot sherry and had coffees which came to approximately 45 Cypriot pounds. There is an extensive menu for other starters and main courses if you didn't fancy the meze.
To Ploumin Sotira Near Ayia Napa: Super wedding reception location
If you are getting married in Cyprus and are looking for a place for your reception then this is the place to book. Costas and his family made our wedding day just perfect. We ordered the meze, we have never seen so much food, Costas arranged some live music, and we were all looked after very well. The whole evening was fantastic, and compared with the prices of hotel receptions it was excellent value.
The following week the remaining six of the wedding party went for a meal, again a fabulous night of super food, wine and entertainment. mixing with the locals.
Favorite Dish: the meze is great but the the smaller eaters the beef stifado and the vine leaves are excellentRelated to:
- Romantic Travel and Honeymoons
Sotira Hotels0 Hotels in Sotira
Instant Answers: Sotira
Get an instant answer from local experts and frequent travelers


text:
As Leaders go John Smith is something of a novelty. He did not campaign for the leadership as the darling of the left and then outrage his supporters by revealing himself as a man of the right.
His appeal was of a different kind. He studiously avoided any ideological commitment apart from vague phrases about a juster and more caring society. His promise was to be a shrewd and prudent managing director for British Capitalism plc. The implication was clear. This is a man you can trust. He will look after you like your family doctor. After the hysterical abrasive raving of Neil Kinnock some Labour supporters might have found relief in John Smith's more comforting message.


text:
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C and O Canal TowpathRead MoreWhile the Chesapeake and Ohio Canal runs along much of the Potomac River, from the District of Columbia out to Cumberland, Maryland (a distance of more than 180 miles), Washingtonians are most familiar with the portion between Georgetown and the Maryland border. This section of the C&O Canal, which opened around 1830, is quite quaint, meandering between 19th-century townhouses and updated office buildings. As you head out of Georgetown, the towpath runs parallel to the C&O Canal, making it perfect for hikers, bikers and early-morning runners. While the mule-drawn canal boat ride is no longer available in Georgetown, you can ride it in Great Falls between April and October, with National Park rangers dressed in period clothing serving as tour guides, providing perspective on life along the canal.1057 Thomas Jefferson Street NorthwestWashington, DC US
Excellent ToursRead MoreLicensed professional tour guides could tell you about the design plan of the U.S. Capitol, the specifics of the congressional resolution to build the Martin Luther King, Jr. Memorial, and the quotes engraved on the Franklin Delano Roosevelt Memorial. Or, they could show you. Excellent Tours' four experienced guides share their knowledge of the capital during three narrated tours aboard vans, mini-buses, and coach buses. Each tour includes stops at the White House, Capitol building, Lincoln Memorial, and Martin Luther King, Jr. Memorial, which is where the similarities end. Tours run at three different times and visit several different additional sights, such as the Thomas Jefferson Memorial and the World War II Memorial. During each excursion, guides divulge facts such as how President Theodore Roosevelt gave the White House its name in 1901, and why the engineer who laid the cornerstone of the Washington Monument used the same trowel George Washington used nearly a century earlier instead of the nice one his mother bought for him.2020 NW K St.Washington, DC US
Uncork'd ArtRead MoreUncork'd Art's instructors invite artists of all skill levels to let their creativity flow while practicing no-pressure painting. During their adult classes, experienced local artists unlock latent talents with a complimentary glass of wine, a brought-from-home snack, and muses equipped with brass knuckles. Instructors lead students in painting experiments during Just For Fun sessions, and provided materials allow for the creation of acrylic-adorned masterpieces. Throughout the 6-week art- and wine-appreciation course, students learn theories and techniques, sample fragrant vinos, and produce three finished paintings. Uncork'd also offers private parties for groups of 10 or more, as well as happy-hour classes, which include helpful instruction with complimentary wine and supplies. Prospective pupils can schedule their next creative frenzy by perusing the online calendar.1054 31st St. NWWashington, DC US
Dumbarton HouseRead MoreAnyone who visits Dumbarton House follows in the footsteps of the country's fourth First Lady, Dolley Madison, who took shelter there as the War of 1812 raged and the British army edged closer to the White House. Since her visit, the Americans have defeated the British, and the house has been transformed into a museum with a collection of more than 1,000 historical artifacts that transport visitors back to the United States' formative years. Once inhabited by Joseph Nourse, the first Register of the Treasury, from 1804 through 1813, the home showcases the family's documents, such as journals, as well as furniture, silver, and other federal period decorative art from the turn of the 19th century. The house itself was built in the same period, exemplifying the clean lines and symmetry that characterized the era's Federal architecture, with wings on either side of its main block.2715 Q Street NWWashington, DC US
The Mansion On O StreetRead MoreOriginally the residence of U.S. Capitol architect Edward Clark, O Street Museum's five interconnected townhouses today enfold a private club, luxury hotel, conference center, and museum. The O Street Museum explores the creative process with more than 1,500 ever-changing exhibits, including handwritten manuscripts, animation stills, and autographed items from such musicians as Bob Dylan and Bruce Springsteen. Shedding the restraints of a standard museum, O Street grants guests the freedom to leaf through collections of photographs and letters from visual artists or gently cradle sleeping sculptures in their bare hands. Themed tours for groups or individuals unveil the subtleties of the museum's elegant space, adorned with original, hand-painted ceilings and Tiffany stained-glass windows. Immersive special events include the Raw and Exposed program, which draws from the museum's vast archives as it presents rare recordings from artists such as Janis Joplin and The Beatles. Amateur and seasoned musicians unite on stage during weekly jam sessions, and the SRO concert series fills the museum's intimate space with one-of-a-kind gospel performances, drag shows, and sock-puppet reenactments of the Revolutionary War.2020 O St NWWashington, DC US
Corcoran Gallery of ArtRead MoreContemplate an original Picasso, imagine yourself Andy Warhol's muse, and then trace Monet's brushstrokes, but save time to appreciate the architecture as well. Inside this historic Beaux Arts building, every corner presents a new feast for the eyes, whether it's a contemporary photograph, European painting, or the gallery's stunning glass roof.500 17th Street NorthwestWashington, DC US


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Michael Schwartz of Valley of the Suns writes:
Although the Suns are prohibited from trading Scola until next July 1 (and can never trade him to Houston), depending on where his salary comes in at they just acquired a very attractive future trading piece. Even as he ages a durable, productive and cheap power forward is the kind of trade chip the Suns have lacked in recent years when frankly there has not been much of interest to entice trading partners.
This was a rather curious move. As we can infer from the Rockets' decision, there isn't a market for Scola. The types of asset from which the Suns would benefit–young players and draft picks–were what the Rockets themselves had pursued and obviously, after that search turned dry, they chose the route of amnesty. Only contenders would have interest in the 32 year old and contenders don't have desirable pieces with which they're willing to part. The best case for Phoenix would be nabbing a late first rounder from someone near the top, but even then, they'd have to swallow quite a bit in undesirable deals for a match.
Not so unlike the Rockets' addition of Sam Dalembert last summer, this is a peculiar move for a team that has made nothing but that type since its glory days early last decade. After breaking up the league's most potent offense over financial concerns and eventually allowing Amare Stoudemire to walk, the Suns quickly squandered that money 'saved' by inking the likes of Josh Childress and Hakim Warrick to offensive deals. They then held on to Steve Nash while he still held value.
The moves for Goran Dragic and Eric Gordon (the latter not coming to fruition) signaled steps in the right direction. But adding the 32-year-old Scola pushes Phoenix towards the middle doing nothing in the way of providing a foundation for the future. As we in Houston know, mediocrity can be painful and difficult to reroute from. Luckily, with their decisions this summer, and the ones still pending, the Rockets seem to be headed clearly either up or down. It looks like Phoenix might be placing a bid for Houston's resident 14 spot.


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David Arquette at the Late Show with David Letterman to promote the new season of 'Dancing with the Stars' in New York City.
Kendall and Kylie Jenner both just stepped out in crop tops. Who wore it better? Check out the pics below!
It's no secret that Ryan Reynolds is ridiculously good-looking.
Taylor Swift might not approve…


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Broan BN190 Belt$6.34This is a Package of (2) geared belts for Broan power nozzle model BN190. The BN190 is manufactured by Centec Systems and has the belt number listed in the manual as #EB24010. This belt is also known as belt #20-5285 or #46-3300-03. Learn More
Broan BN180 Belt$5.34This is a Package of (2) Flat belts for Broan power nozzle model BN180. Learn More
Broan Microfiltration Central Vacuum Cleaner Bags With Closure Seal, Broan Part 391$16.00Broan Microfiltration Central Vacuum Cleaner Bags With Closure Seal, Broan Part 391 Learn More
Broan-NuTone VX3918STD 8-Gallon Bag Standard Filter Media Bags For VX550 and VX1000 Series, 3 Per Pack$19.14Broan-NuTone VX3918STD 8-Gallon Bag Standard Filter Media Bags For VX550 and VX1000 Series, 3 Per Pack Learn More
Broan-NuTone CA101G Clip-On Tool Caddy For Central Vacuum Hose Wand, Gray$17.39Broan-NuTone CA101G Clip-On Tool Caddy For Central Vacuum Hose Wand, Gray Learn More
Broan-NuTone CT106G Upholstery Tool Central Vacuum Hose Attachment with Removable Brush and Nylon Bristles$11.50Broan-NuTone CT106G Upholstery Tool Central Vacuum Hose Attachment with Removable Brush and Nylon Bristles Learn More
GarageVac GH-120 Red Wall Mounted Garage Utility Vacuum by InterVac$249.50The wall mounted model GH-120 GarageVac saves valuable floor or wall space and keeps the vacuum tools at your fingertips. You won't loose any tools or misplace the hose everything is in one spot ready to clean. Learn More
GarageVac Flush Mount Vacuum White GF120 (W)$269.50GarageVac Flush Mount Vacuum Learn More
GarageVac Surface Mount Vacuum White$249.50GarageVac Surface Mount Vacuum Learn More
GarageVac GH-120 Black Wall Mounted Garage Utility Vacuum by InterVac$249.50The GarageVac by InterVac is an easy to use, all in one central vacuum cleaning system designed for your garage, but can be installed in mobile homes, RV's, airplanes & boats. The wall mounted system can be installed in under ten minutes! There is no piping required, just a screwdriver. Learn More
GarageVac GH-120 White Wall Mounted Garage Utility Vacuum by InterVac$249.50GarageVac GH-120 White Wall Mounted Garage Utility Vacuum Learn More
Outside Diameter PVC Pipe Designed For Central Vacuum Systems$119.99This is 2" outside diameter PVC pipe, designed specifically for central vacuum systems. Regular Schedule 40 (SCH-40) PVC pipe is normally 2" inside diameter, but 2.5" outside diameter. The normal SCH-40 PVC pipe, because of it's thicker inside diameter Learn More
Plastiflex 30 Foot Low Voltage Crush Proof Hose SGE-138-30-N$72.00This Plastiflex 30 Foot Low Voltage Crush Proof Hose works with Beam, Vacuflo, MD and other central vacuum systems. Part Number SGE-138-30-N Learn More
Plastiflex CBEZ125035I 35FT Dual Voltage Electric Hose W/ Pigtail Cord$178.00Plastiflex 35 foot hose with pigtail. This Plastiflex 35 ft hose can be used with almost any central vacuum system on the market. CBEZ125035I is the part #. Learn More
Plastiflex SGE13835BLI 35FT Low Voltage Hose With Button$150.4835FT low voltage hose that works for systems like Beam, Nutone, Vacuflo, etc. 35 foot lv hose for your central vacuum systems built-in your home. SGE13835BLI Learn More
Central Vac White Vacpan Part # VCPW01$32.95Central Vac White Vacpan Part # VCPW01 Learn More
Plastiflex Universal Inlet Valve Fitting (White) FT50WP$7.99Plastiflex Universal Inlet Valve Fitting (White) FT50WP is a valve fitting that is one of the most commonly use for the past 20 years. This fitting is specifically for Central Vacuum Systems that use Corded Inlet, Pig Tail, or Low Voltage designs. Learn More
Plastiflex Short 90 Degree Tee Central Vacuum Fitting +$5.83Plastiflex Short 90 Degree Tee Central Vacuum Fitting. Learn More
Plastiflex 35ft Electrical Central Vacuum Hose Direct Connect Style w/ Push Button Lock$199.89This is a 35ft electrical hose, direct connect style. The end of the hose that plugs into the wall, has a 2 high voltage male pins that plug into a high voltage female outlet, in the outlet itself. If your hose has a 6-8 pigtail extenstion cord that plugs into a normal household outlet, this is not the right hose. This is for homes with newer contruction that have high voltage as well as low voltage current running to their outlets. Learn More
Plastiflex Sweep 90 Degree Central Vacuum Fitting$6.08The sweep 90 degree fitting is probably the most common fitting, besides the coupling. This is what you want to use when diverting your pipe run 90 degrees, instead of the short 90. Learn More
Plastiflex 90 Degree Single WYE Central Vacuum Fitting +$6.23This is a 90 Degree Single WYE Central Vacuum Fitting used in all vacuum cleaners. Learn More
Plastiflex 30FT 1 1/4 Dual Voltage Electric Hose Direct Connect Part # CBEZ125030N +$173.8430-Foot High quality electric vacuum hose for nearly all central vacuums (except Electrolux, Beam, Hayden, Hoover, AirVac, Vacumaid). You will love the quality of this hose - crushproof, lightweight, and 360 degree swivel handle! In fact it has 27% more air flow than hoses manufactured before 2004. Comes with 100% Satisfaction Guarantee and 30 Day Refund. Learn More
Plastiflex 35FT 1 1/4 Dual Voltage Electric Hose W/ Pigtail Cord Part # CBEZ125035I +$177.84This Plastiflex 35FT 1 1/4 Dual Voltage Electric Hose comes with a Pigtail Cord and it can be fitted into any vacuum cleaner models. Learn More
Plastiflex 35ft Hose Sock with Application Tube$28.94Instantly increase your central vacuum satisfaction with a vacuum Hose Sock Cover. One of the most overlooked items on the menu, a Hose Sock is the finishing touch you don't want to miss. Make any central vacuum hose: - Easier. Glides over all surfaces. - Safer. Protects baseboards, furniture. - Quieter. Insulates hose noise. And the hose sock does this without adding any noticable bulk. Learn More
Plastiflex 30ft Non-Electric Hose$49.99Plastiflex 30ft Non-Electric Hose Learn More
35ft Hose Sock, Grey$23.9935ft Hose Sock, Grey Learn More
30ft Central Vacuum Zippered Hose Sock Cover$17.40THESE COME IN ASSORTED COLORS Learn More
Results 1 - 27 of 27


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- Oilers sign No. 1 pick McDavid to 3-year, entry-level deal Updated: Jul-03-15 1:56 pm
EDMONTON, Alberta - Connor McDavid played 66 junior games for the Erie Otters this season and seven more at the world junior championship. Even when the hockey stopped, there was more to do.
- Spieth wins a stunner at Chambers Bay for US Open title Updated: Jun-22-15 12:23 am
UNIVERSITY PLACE, Washington - Jordan Spieth is halfway home to the Grand Slam, a prize only three of the biggest names in modern golf have ever chased.
- The Next One? Gretzky's son Trevor follows baseball dreams Updated: Jun-18-15 5:20 pm
CLINTON, Iowa - Trevor Gretzky is known more for his iconic last name than his baseball career.


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And too few insights gleaned from them
Pluripotent Until Needed
April 1, 2013|
Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.
April 1, 2013|
Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.
April 1, 2013|
Flies turning blue help researchers link the deterioration of the intestinal barrier to age-related death.
April 1, 2013|
Archaeology can shine needed light on the evolution of our aggressive tendencies.
March 2, 2013|
Drosophila insulin-like peptides (dILPs) regulate part of the signaling pathway that helps keep organs growing in proportion during development.
March 1, 2013|
Meet some of the people featured in the March 2013 issue of The Scientist.
March 1, 2013|
During development, communication between organs determines their relative final size.
February 11, 2013|
A small insect-eating animal is the common ancestor of whales, elephants, dogs, and humans.
February 1, 2013|
Collective cell migration relies on a directional signal that comes from the moving cluster, rather than from external cues.
February 1, 2013|
Watch the cell transplant experiments in zebrafish that suggest certain embryonic cells rely on intrinsic directional cues for collective migration.
December 14, 2012|
The science images and videos that captured our attention in 2012


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We study theoretically and numerically the influence of thermal effects on the cross-gain modulation (XGM) characteristics of vertical-cavity semiconductor-optical amplifiers. We show that heating of the device may lead to noticeable modifications of the XGM efficiency spectrum, leading even to negative XGM efficiency, in good agreement with recent experimental results
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Kettal and Patricia Urquiola create Kettal Cottage: a part tiny house, part tent escape
Spanish architect and designer, Patricia Urquiola, creates unique furniture pieces and her collaboration with furniture manufacturer Kettal has resulted with interesting lines of outdoor furnishings that
Portland architecture students build incredible outdoor stage from 520 recycled pallets
Calling all indie music fans! Oregon's Pickathon Indie Roots Music Festival is coming to life this August, and we've got your inside look at the awe-inspiring, sustainably crafted stage designs which make
Thomas Kroeger Architekt transformed this 19th-century barn into a gorgeous holiday home in Germany
This 19th century Lanhaus-country house- is located in a small village near Berlin. The architects renovated its large double-height hall, removed damaged and rotten structure, leaving the well preserved
Winners announced for the 2015 eVolo Skyscraper Competition
The first place was awarded to BOMP (Ewa Odyjas, Agnieszka Morga, Konrad Basan, and Jakub Pudo) from Poland for their project Essence Skyscraper. The proposal is an urban
Foster + Partners reveal plans for new metro system in Jeddah, Saudi Arabia
Award-winning architecture firm Foster + Partners has been chosen to create a new city-wide public transportation plan for Jeddah—one of the most vibrant city centres in Saudi Arabia. F+P came out
Spaceship-like ski chalet sheds snow with its sharp crystalline form
Commissioned by Martin and Sue Hadaway, the eponymous 460-square-meter home is clad in ipe hardwood planks and punctuated by shard-like glazing strips and black steel. The shape of the geometric
Berlin's Tchoban Foundation Museum shelters architectural history within an energy-saving, hand-drawn concrete facade
Resolutely modern, the Tchoban Foundation's Museum for Architectural Drawing springs forth from the end of a row of hundred year old apartment buildings at the entrance to the Industrial monument known
'Raven Loft' is a small, sustainable treehouse home in BC, Canada
The story of Raven loft started with the idea to live simply, sustainably, and low-cost. Geoff de Ruiter, owner of Raven Loft, bought a half acre forested plot of land for $35,000 through a court ordered
Czech Republic's prefab pavilion is built around a swimming pool to keep cool at the 2015 World Expo
The three-story, prefabricated pavilion features a long rectangular swimming pool with a bar at its entrance. Inside, visitors will have a choice of three restaurants as well as a series of exhibition
Historic Australian church is transformed into a modern residence
The historic stone chapel was built in 1877 from bluestone. Although the religious effects are long gone, the façade still boasts the original church bell, which rang for the small village that
Murman Arkitekter's timber-clad sauna soaks up stunning seaside views in Stockholm
Murman Arkitekter created this timber-clad sauna for a seaside home on the Stockholm archipelago. The sauna has two wings which gentle fold out toward the Baltic Sea, allowing it to soak up the warmth of
Konya City Stadium's faceted astro-turf facade reflects the colors of the city's football team
The stadium is covered with artificial turf heated from below, with white-green colors of the local team. High-tech materials were used for the construction of the steel roof and facade, while the
Elegant timber extension uses angular volumes to maximize natural light
The two-level addition extends diagonally from the back of the house. A sloped roof section that connects the original cottage to the timber extension doubles as an angular overhang that protects the home
Facit Homes' D-Process creates buildings that snap together like LEGO bricks
Using D-Process, Facit Homes designs each building on a computer in extremely detailed pieces which are then cut on a CNC router. The building components are shaped into LEGO-like cassettes and are
Grand Cancun eco island cleans up the ocean while generating renewable energy
The entire surface of the offshore platform will be covered in solar panels that will provide energy for both Grand Cancun and the main city's national grid. Vertical wind turbines and underwater tidal
Daniel Libeskind's funky metallic apartments will purify the Berlin air
Architect Daniel Libeskind just unveiled plans for a modern, metallic apartment complex located in the heart of Berlin. Projected for competition in 2015, the eight-story tall Chausseestrasse 43 building
Refuge du Goûter: Space-Age Self-Sufficient Alpine Lodge is the Highest Building in France
Located on one of the most popular routes used by climbers hoping to scale Mont Blanc, the Refuge du Goûter took five years to plan and three more to build. Dubbed a 'high-altitude hotel,' the project
A++ Architecture Unveils Plans for Shipping Container Homes in Bodrum, Turkey
A++ Architecture recently unveiled plans to construct a cluster of net zero energy buildings in Bodrum, Turkey. The new development will feature a number of highly efficient, low cost homes made from
Grandparents Build a Fairytale Treehouse for Lucky Grandchildren
A couple of lucky boys in Dallas have their very own fairytale treehouse that was built for them by their grandparents. Steve and Jeri Wakefield hired James Curvan to design the multi-level treehouse,
Nation's largest shipping container restaurant was installed in just 3 days
Located on a former brownfield along the French Broad River, the Smoky Park Supper Club is a shining example of adaptive reuse and brownfield reclamation. Logan, owner of the downtown Asheville restaurant
Morphosis plans ultra-thin reflective skyscraper for Swiss resort valley
The '7132 Tower' is intended to be an impressive and eye-catching feature in itself, but the architects also worked to make sure the building cooperates with its beautiful natural environment. To that
Updated: Star Wars Tatooine villages in Tunisia are safe from ISIS
The infamous Tunisian Star Wars sets, that represent Luke Skywalker's desert planet of Tatooine, have had it rough in the past. If it's not Imperial Stormtroopers, then the sets are being threatened by
James Whitaker designs funky light-filled office space out of shipping containers
An advertising agency commissioned Whitaker to develop the Hechingen Studio design as a low-cost cargotecture workspace near the rural German town of Hechingen. Although the project was never
Azerbaijan's 2015 Expo Pavilion Keeps a Small Energy Footprint Inside a Slatted Timber Shell
The designers created a modular system within the Azerbaijan pavilion so that various levels can be reconfigured to accommodate a variety of different uses. Each floor is connected via an escalator and
A Church in the Netherlands has been converted into a house of coffee worship
An 18th-Century abbey in the Netherlands has been transformed into a center of worship for caffeine and great conversation. Located in the hamlet of Abshoven in the Dutch province of Limburg, the
Vo Trong Nghia Unveils Towering Bamboo Lotus Pavilion for the World Expo 2015
Vo Trong Nghia's lotus pavilion was inspired by local flora, but it holds a universal message. "Growing from the muddy ponds it rises above the surface to bloom with remarkable beauty. The flower is proof
Classic Eichler renovated into a naturally-cooled home that blends indoors and out
Klopf Architecture recently remodeled a classic Eichler mid-century home, honoring the iconic home's style while expanding it to suit the needs of the new homeowners. Working along side Arterra
Samoo Architects & Engineers reveal plans for Ulju Government Complex in South Korea
The architects designed the project as an attempt to combine history, nature and accessibility and create diverse spaces within the complex. While there is a high degree of independence between different
SelgasCano unveils colorful chrysalis-like designs for the 2015 Serpentine Pavilion
Spanish architects Jose Selgas and Lucia Cano of SelgasCano just unveiled designs for the 2015 Serpentine Pavilion, a temporary summer structure to be built in London's Kensington Gardens. Commissioned
Henning Larsen Architects reveal plans for a new mosque in Copenhagen that marries Islamic and Nordic design
Henning Larsen Architects has released its plans for a new mosque and Islamic community centre in Dortheavej—an area in northern Copenhagen, Denmark. Commissioned by The Islamic Society of Denmark,
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Outdoor Living
Lifetime 6 Foot Folding Outdoor Picnic Table (Brown) 60110$129.99
Product Description
The Lifetime 6' Picnic Table gives you that perfect extra outdoor eating space you've always wanted. Constructed of UV-protected high-density polyethylene and powder-coated steel, our picnic tables are weather and rust resistant, and will not fade, crack, chip or peel. Stronger and more durable than wood, they are low-maintenance, stain resistant and easy to clean. Best of all, Lifetime picnic tables fold completely flat for convenient storage.
Product Features
- Table top/frame color: brown/bronze
- Frame material: powder-coated steel tubing
- Table top material: UV-protected double-wall, High-Density Polyethylene (HDPE)
- Seats 8 comfortably
- Superior strength and durability
- Folds flat for storage
- Stain resistant and easy to clean
- Includes umbrella hole and cap
- Attractive wood grain design
- Will not crack, chip, rust, or peel
- Steel frame with all-weather finish
Product Specification/Dimensions
- Table Top Thickness: 55 mm
- Frame Tubing Diameter: 42 mm
- Bench dimensions: 19" H x 9" W x 72" D
- Overall dimensions (Open): 29" ;H x 30" W x 72" D
- Overall dimensions(Folded): 4" H x 57" W x 72" D
- Weight: 76 lbs
Wicker Hanging Chair 913478
Regular Price: $249.99
Special Price: $149.99
Product Features:
- Made of Resin Wicker
- Sturdy Steel Frame
- For Indoor or Outdoor Use
- Easy Assembly
- Weight Capacity: 250 lbs.
- Dimensions: 75.6" x 19.3" x 37"
Cajun Injector Vertical Gas Smoker 22174.07040$149.99
If you want great results when smoking any types of food, the Cajun Injector Gas Smoker is your answer for smoky, flavor-filled moist meat, poultry, and fish every time you smoke! Use your new smoker for BBQ ribs, sausages, beef jerky, brisket, and so much more!
Product Features:
- Low Pressure Gas Regulator
- Dial Temperature Control
- Chrome Plated Grilling Racks - allows ample room for cooking all types of meat
- Temperature Gauge
- 2 Adjustable Door Latches
- Steel Wood Chip Box
- Porcelain Coated Water Bowl - keeps food moist
- Uses Propane Gas Bottles
- Instruction Guide Included
- Air Damper - better smoker control
- 2 Handles - for easy handling
S & D International Harvester Park Bench 77723$129.97Product Features
- Made with cast iron legs and wooden slats with cast iron insert in back!
- Assembly Required
Char-broil Electric Vertical Smoker-11201677$129.99
Product Description
- 1,500 watt heating element with three temperature settings
- Three adjustable, oven-style, chrome-plated grates provide 504 sq. inch total cooking surface area
- Porcelain-coated wood chip and water pan
- Porcelain-coated ash pan
- Chrome-plated handle
- Temperature gauge
Learn More
Jordan, 2 Person Wooden Glider Bench (Black), 3N2GLALPL$149.97
Product Features
- Two Person Gliding Bench
- Acacia Wood
- Black UV Treated Painted Finish
- Assembly Required
- Dimensions: 51" x 25" x 34"
Aspen Single Chair Pine Tree TX94205$149.97
- Has a small pine tree cutout on the back rest
- Durable log construction
- Patent pending crack resistant design and process
- Varnished to preserve finish
- Natural wood finish
NewAir 18 in. Ultra Quiet Outdoor Misting Fan AF-520B$129.97
Attractive and wonderfully designed, the NewAir AF-520B misting fan is a great addition to any backyard or patio setting. This fan creates a cool and comfortable patio area for family and friends to enjoy. You'll enjoy the gentle, continuous mist this fan emits to keep you feeling cooler on a hot day!
- Durable construction to weather outdoor elements
- Extended misting to 500 sq. ft.
- Oscillates for widespread cooling
- Push button controls are user-friendly
- Tilting head and adjustable height allows for targeted misting
Product Features:
- 18" Oscillating Fan Head - If you love the outdoors but can't stand the heat, then consider adding the NewAir AF-520B misting fan to your outdoor living space. The NewAir AF-520B is designed to provide a cooling mist to widespread areas. Adjust the oscillating fan head vertically to direct airflow and cooling mst where you need it most. This fan is designed to provides loads of outdoor comfort.
- Large Coverage Area - If you're buying a misting fan, you want one with the power to keep you feeling great! The NewAir AF-520B 18" outdoor misting fan offers enough cooling coverage for nearly 500 sq. ft. of patio space. This great feature allows you to enjoy a refreshing outdoor setting and keep the backyard area comfortable.
- Stylish Design - When you add to your outdoor decor, you want something that looks good and complements your lifestyle. This beautifully designed misting fan features a elegant black finish that blends with virtually any decorative style perfectly. This fan is a great way to keep your patio area comfortable and looking great at the same time.
- 3 Speeds - The NewAir AF-520B 18" outdoor misting fan is especially designed to provide advanced cooling control. Choose your own comfort level and enjoy as little or as much misting as you like with this easy to use 3 speed fan. This custom feature allows you to personalize the atmosphere for an ideal result everytime.
- Strong and Durable - This NewAir AF-520B 18" outdoor misting fan is designed for outdoor use. Manufactured using only the best materials and featuring a 3 prong GFCI plug for safe use, this fan is guaranteed to weather outdoor elements and provide reliable and advanced cooling. If you're looking for a dependable, attractive way to cool your outdoor area, then you can't go wrong with the NewAir AF-520B.
Learn More
Specifications Model AF-520B Product Type Outdoor Misting Fan Dimensions 19.38" x 19.38" x 55.00" Weight 16 lbs Color Black Max Air Flow 2475 CFM Diameter 18" Oscillation Yes Usage Outdoor Certified for Commercial Use No Energy Star Certified No Standard CFM 2475 CFM Fan Style Pedestal Product Construction Plastic Adjustable Tilt Yes Coverage Area 500 sq. ft. Adjustable Height Yes Number of Speeds 3 RPM 1230 Remote Control No Timer No Number of Nozzles 3 Built-in Air Purification System No Plug-in 3 Prong GFCI Plug Cord Length 5' 6"
Grillbot Red Grill Cleaning Robot GBU101-RED$129.97
This is how to clean a grill — with the world's first automatic grill cleaning robot. Simply place the GRILLBOT on your grill, press a button and you're done. It does all the grill cleaning for you — no more scrubbing! After the party, don't clean the grill. Order your GRILLBOT today and let it take care of that messy grill for you!
Product Features:
- Push-button operation
- Three powerful electric motors
- Built-in LCD alarm & timer
- Smart computer brain to regulate speed and direction
- Rechargeable battery with AC adapter
Real Flame Mezzo Round Propane Tank Cover 616$131.97
Cast from a high performance, lightweight fiber-concrete with an outdoor safe finish, this tank cover conceals your 20 lb propane (LP) gas tank, even while in use. The cover doubles as an table while coordinating with the Mezzo Round and Square Fire Tables. The Mezzo Collection is ETL certified and available in Flint Gray or Antique White finishes.
Product Features:
- Securely holds and covers a 20 lb propane (LP) gas tank.
- Cast from painted fiber-concrete and steel.
- Includes: 20 lb LP tank cover, Tank Seat, Leveling Feet.
- 90 day limited warranty.
- Basic assembly required.
- 20.625 Inches High
- 16.25 Inches Wide
- 16 Inches Deep
** Tank not included!Learn More


text:
February 2009, Volume 1 Number 1, p 58 - 60
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February 2009, Volume 1 Number 1 , p 58 - 60
Beebe, Victoria
Issue: Volume 1(1), January/February 2009, pp 58-60 Publication Type: [DEPARTMENTS: NP Connections] Publisher: © 2009 Lippincott Williams & Wilkins, Inc. Institution(s): Victoria Beebe, CPNP, Lahey Clinic, Burlington, Massachusetts. Correspondence concerning this article should be addressed to Victoria Beebe, CPNP, 41 Mall Road, Burlington, Massachusetts 01805. E-mail: email@example.com
In 2003, like many hospitals and healthcare centers across the country, Lahey Clinic in Burlington, Massachusetts, was facing a paucity of dermatologists. Patients confronted long wait times for appointments and difficulty scheduling follow-up visits. Dr. Suzanne Olbricht, a Mohs surgeon and chief of Lahey's dermatology department, had experience working with nurse practitioners (NPs) in dermatology. She felt that there was a role for NPs in dermatology and foresaw their use as part of the solution to the shortage of dermatologists. Although ...
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