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59 of 61 people found the following review helpful
4.0 out of 5 stars Ways of Seeing
It's been five years since Jamie's collection 'Findings', so I looked forward to this with eager anticipation; nor was I disappointed. She dedicates this collection of pieces to "the island-goers", even though the settings include Bergen, Central Scotland, and a Pathology Lab at Ninewells Hospital in Dundee; happily islands such as Rona, St Kilda and Shetland also...
Published on 25 Mar. 2012 by Sentinel
3.0 out of 5 stars for all its best intentions, is a bland repetitive experiment
Sightlines, for all its best intentions, is a bland repetitive experiment. Despite an intention of naturalism, without romanticism as the critics insist, this collection of essays is neither a profound exploration of human experience, or fully devote poetry to the natural. Often the essays, rather than finding a sweet medium between the complexity of the 'man-made' and...
Published 10 months ago by om
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59 of 61 people found the following review helpful
4.0 out of 5 stars Ways of Seeing,
Sentinel (Essex) - See all my reviews
This review is from: Sightlines (Paperback)
It's been five years since Jamie's collection 'Findings', so I looked forward to this with eager anticipation; nor was I disappointed. She dedicates this collection of pieces to "the island-goers", even though the settings include Bergen, Central Scotland, and a Pathology Lab at Ninewells Hospital in Dundee; happily islands such as Rona, St Kilda and Shetland also appear.
These essays, or perhaps 'meditations' is a better term, range in length from two to about 30 pages, long, and each are beautifully illustrated by stylish b & w photos. Whether describing the synchronised,shining curves of a pod of orcas, the eyes of gannets, "round and fierce, with a rim of weird blue", or the irregular surface of a cancer tumour, named "for the crab, because a cancer tumour sends claws out into the surrounding tissue", her eye continues to offer unusual poetic or challenging perspectives, especially when she pictures parts of the human anatomy as a landscape of land and river margins, mud-flats et al.
Her eye extends to an archaelogical dig, "the bite on the point" of her trowel, and the discovery of the woman in the cist burial. Although her sharp eye also catches the "glowing marshmallow pink" of icebergs in the morning sun during an Arctic cruise, her ear also delights in the charm of the "di-diddle-ditted" of a petrel in its burrow on Rona, responding to the tape recording played at its burrow mouth. There's also the account of her determined attempts to overcome the ocean's might, to finally describe the isolation of St.Kilda at her third attempt, and an almost hypnotic encounter with the curving power of cetacean skeletons in the 'Whale Museum' in Bergen.
Overall, this is an insightful and largely inspiring set of writings, with the marvels of the natural world predominant. I confess to feeling that the piece on 'Pathologies' was not to my taste, and felt it sat rather uneasily amongst the other writing, though I can see the link with other pathologies, including the cist burial. Hats off to 'Sort Of' books for some lovely paperback production values: clear typesetting, gorgeous cover art, illustrations, and the book's 'feel' in your hand.
27 of 28 people found the following review helpful
5.0 out of 5 stars Lyrical, contemplative nature writing,
M. Harrison - See all my reviews
This review is from: Sightlines (Paperback)
Having absolutely loved Findings, Scottish poet Kathleen Jamie's previous collection of essays, I was very excited to read Sightlines. Also inspired by the natural world, it is just as quiet and contemplative, and revisits some of her previous subjects - sea birds, islands, pathology - as well as the aurora borealis, a lunar eclipse, archaeology, whales' jawbones and a dead storm petrel she finds on St Kilda.
But as with Findings, this is more than just `nature writing'. Jamie uses each of her closely observed subjects as a jumping-off point for a meditation on our relationship to the object in question, its position in time and in the world, and its personal significance for her. The result is a series of spare yet lyrical essays that continue to resonate long after you have put the book down. Wonderful.
4 of 4 people found the following review helpful
5.0 out of 5 stars 'Part of that rough tribe of the mortal',
Laura T (Oxford, UK) - See all my reviews
This review is from: Sightlines (Paperback)
I'm a great fan of the increasingly popular genre of 'nature writing', with recent favourites including Robert Macfarlane's 'The Wild Places' and Philip Connors' 'Fire Season'. However, although it is not a genre that tends to produce terrible books, it can tend towards mediocrity; good descriptive writing abounds but truly exceptional work is rare. That's why I was delighted to discover this marvellous book of essays - and sad that I hadn't come across Kathleen Jamie's work earlier. ('Findings', her first collection, has shot right to the top of my to-read list).
These essays are an eclectic mix, spanning place, subject, and length - some are only a few pages long, others much longer. But nearly all are outstanding in one way or another. Jamie opens the collection with 'Aurora', a description of a journey towards the northern lights that is possibly the best piece she presents here, and certainly my favourite. What Joanna Kavenna struggled to do in hundreds of pages in her turgid 'The Ice Museum', Jamie manages in less than twenty, moving evocatively from a description of the 'colossal, witless indifference' of the surrounding icebergs themselves, to the radar screen that marks them out as a 'rash of green dots'. She is also not above humour, which conveys a vital sense of herself and avoids the overly-stylised journalistic tone that sometimes afflicts travel writing. Reporting that some suggest that you can hear your own nerves working in the Arctic silence, she goes on to say that 'Some people say you can smell icebergs, that they smell like cucumbers. You can smell icebergs and hear your own nervous system. I don't know.'
I have reviewed this first essay in such depth because its strengths are, largely, the strengths of the other essays in this collection. As well as being a wonderful writer, Jamie is also superb at structure. This is demonstrates most strongly in a later piece, 'The Gannetry'. Her sighting of the fin of a killer whale and race to follow the animal's path around the island is infused with tension; you don't expect nature writing to be page-turning, but this is. However, a structural choice that is, in my opinion, even more effective, is her juxtaposition of the description of the gannetry with reflections on her relationship with her son. This is initially frustrating when a seemingly irrelevant description of a text conversation between them interrupts the description of the killer whale chase, but is brought full circle when she reflects at the end of the essay that killer whale packs are matriarchal, meaning that grown sons remain with their mothers. There's no need to spell out her own feelings about her son growing up and moving away from her, as she's done it all already.
As is probably obvious, I could quote endlessly from these essays, especially my other favourites, 'The Woman in the Field', 'Pathologies', 'On Rona', and 'Three Ways of Looking at St Kilda', but this review is already long. The only pieces that didn't quite work, for me, were the shorter ones, but I think this was because Jamie did not give herself space for the full development of ideas that she manages in the longer essays, and not because they were in any way badly-written. I recommend this collection wholeheartedly, and can't wait to read more of Jamie's work.
3 of 3 people found the following review helpful
5.0 out of 5 stars Interesting, absorbing and revealing,
Mrs. K. A. P. Wright - See all my reviews
This review is from: Sightlines (Paperback)
Kathleen Jamie is a Scottish poet. This book is a series of essays roughly grouped round the concept of 'the natural'. This is a wide field encompassing such subjects as Aurora, Pathology, the Hvalsalen (the Whale Hall at Bergen Museum). Natural doesn't necessarily mean living or sentient, but Jamie pulls them all together so that we can appreciate the connections.
These essays are in prose and I hesitate to say that the language is poetic because that term is frequently used damningly (and wrongly) to summon up ideas of flowery epithets and a generally precious and pretentious form of writing. Kathleen Jamie's writing is crystal clear. It is sharp and vivid and when she does use figures of speech they are apt and to the point. I think my favourite was her description of icebergs:
"Some people say you can smell icebergs . . . I smell nothing but colossal, witless indifference."
I really enjoyed this book and I was not sure I was going to. It is a book that I shall revisit, because I think it has a lot more to give than a first reading would discover. She made me consider at things I had largely ignored before and look at them in a way that I would not have thought of doing myself. Highly recommended.
3 of 3 people found the following review helpful
4.0 out of 5 stars Very moving,
trishthedish (UK) - See all my reviews
This review is from: Sightlines (Paperback)
I read this book and was moved to tears at times, her sensitivity towards Nature is to be read to be understood. Actually, I felt this book was hard to describe as such, if you like poetry and Nature, you will get it, if you don't you will not. My husband didn't - his loss, so it depends on where you're coming from. If you know the particular areas mentioned around Scotland and the Isles it helps too, don't think you could fail to be moved in that case, unless you're some sort of android. Will now go back and read other work by the author and possibly re-visit some of the sites again.
22 of 25 people found the following review helpful
5.0 out of 5 stars Thought-provoking beautiful writing - these essays are in another league.,
A. I. McCulloch "Andrea" (Co Durham) - See all my reviews
This review is from: Sightlines (Paperback)
This is an unusual book of essays, taking as its core theme the way we perceive the natural world; when we look at something, what do we see?
This sounds like it would be self-indulgent mind-gabble, but it isn't, these are beautifully crafted pieces of work that delight you with their insight and their use of language.
The description of parts of the human body under the microscope as landscape, was a completely original take on a grimly fascinating subject. It isn't all meditation, there's a lovely recollection of an archaeological dig as a teenager and these slivers of biography add to the human interest within the book.
If I hadn't known that Kathleen Jamie was a poet, I would have probably guessed it from her prose. She has an absolute mastery of language but this never distances you from her writing. I enjoyed her humorous description of the (non)trips to St Kilda as much as the more deeply meditative pieces.
Kathleen Jamie's prose output may be relatively sparse, but masterpieces aren't created overnight. Highly recommended, not just to those who enjoy the natural world, but to all who enjoy good writing.
1 of 1 people found the following review helpful
5.0 out of 5 stars A remarkable book,
Damaskcat (UK) - See all my reviews
This review is from: Sightlines (Paperback)
I loved reading this book and some of its images will stay with me for a long time. The writing style is low key and unselfconscious and at the same time poetic and lyrical. The sea and islands are the predominant subjects with whales and whale bones providing a theme like a red thread running through fabric. Here is nature as a poet and writer sees it. Gannets nest on impossible cliffs, Orcas swim around remote Scottish islands, abandoned crofts and birds which fly at night to avoid predators are all the subjects of this collection of essays.
The desire in some humans to experience remoteness and separation from fellow human beings is well described. At times many crave that silence and isolation which can only be provided by uninhabited lands. But animals and birds are never far from us wherever we go and all are surprisingly well adapted to their living conditions. This is nature writing at its best and it brings everything to life as do the black and white pictures which accompany each essay.
This is a moving and memorable book which brought home to me how interconnected we all are. We don't just live on the earth we are an integral part of it just as animals and plants are. One of the images which will stay with me is that of the author rescuing a moth from a stream and helping it to dry out on a stone and then realising with the aid of a magnifying glass that one of its fragile legs was glued at a strange angle to its wing by a drop of water. Having unglued it the author had to leave the moth to dry out and fend for itself. Did the moth live or did a predator snap it up? Who knows?
1 of 1 people found the following review helpful
4.0 out of 5 stars "what is it that we're just not seeing?",
LittleMoon (loving my life in the rain) - See all my reviews
This review is from: Sightlines (Paperback)
It is a pertinent question for modernity perhaps: "what is it that we're just not seeing?" If Jamie offers anything resembling an answer in this collection of essays, it might be a move towards transparency, towards an imperfect understanding, towards different points of view. Whether she is contemplating the aurora borealis exploding over the skies, musing on the provenance of whalebone arches, or counting rare petrels on the island of Rona, Jamie's writing invites us to look again at the world--a place at once familiar and unexpected.
Not surprisingly considering her quality as a poet is the precision and magnetic beauty of the writing contained in Sightlines. Icebergs are "driven by some sort of life force, flickering and green"; gannets "glitter" and are "[l]ess patrician poet, more bargain-hunter"; the power of the wind is such that "one just finds oneself on one's knees, as if beholding a miracle." Much of the pleasure comes from the way these "meditations" are written, eschewing the rigour of an all-knowing approach for a freeform series of observations and interactions. Personal memories and interest are as important in driving this writing as the facts and data to be gleaned from her amateur and professional companions. This makes the author seem a very unpretentious guide.
I especially enjoyed those essays which focussed on landscape and nature, although my favourite was about the Hvalsalen or "Whale Hall" in the Bergen Natural History Museum. Kathleen Jamie is fortunate enough to spend a few days working with a team restoring some of the whale skeletons. There is something "ancient and fairy story" about cleaning the bones but we are not allowed to forget that these whales have endured the "full gamut of human attention--from the exploding harpoon ... to the soft sponge".
This collection contains 14 essays the vast majority of which are concerned with natural history or landscapes. (There are deviations into pathology, archaeology and cave painting which I found less compelling, but that's my personal taste.) Jamie is at her best, for me, when she is exploring the idea of the natural world and our place within it. Never romantic or sentimental, her encounters with the wilderness are just that, wild. The gannets and killer whales and dramatic island vistas spring from the pages in a frenzy of existence and it is for their very power to offer up this natural world, raw and often unknowable, that these essays excel.
1 of 1 people found the following review helpful
5.0 out of 5 stars the gentle elegant art of the essay,
David Spanswick (Brighton United Kingdom) - See all my reviews
This review is from: Sightlines (Paperback)
I feel certain that a book of essays will rarely become a bestseller and will not appear in the top ten listings in the sunday papers. The essay, as a literary form has an academic anchor, a school chore, an exam question all weighing it down as far from "light" reading and yet every day in newspapers we take on board (or on breakfast table) the journalist's take on the essay as modern information.
Kathleen Jamie is a poet and as we know poets, like policemen, are never off duty. Poets see the world differently; they can not help but see it more lyrically, a world that has more language in it.
In this collection of essays her range is quite extraordinary from the "smell of icebergs", the whale bone museum to the joy of her children playing in the February light and the unexpected beauty in the path lab as she regards a cancerous tumour on the inside of an excised colon. Her poetic choice of language elevates these often rather simple experiences to the level of meditations on life and life and especially on the debt we owe to the natural world that keeps our own ever changing.
Jamie does not shy away from the immediate experience she is undergoing, whether dealing with the grief, as relief, at the death of her mother or sharing the midnight experience of the moon's eclipse with her children; she finds sufficient words to share with the reader the effect that her environment both physical and mental has upon her.
Unearthing history in an autobiographical and symbolic manner fuses her past and her present in the central essay "The Woman in the Field" revealing as , for all of us, that you can never go back. Memory is really our only history. We are all authors of our own fate.
This is a book I will return to time and again as it has a command, an extremely powerful effect on the reader; it is calming. The hush of the sea between the fjords, the wonderment of the enormity of the bones of the whales, gannets glittering the sunlight. This is a book of Images, a book of enduring words; shared memories.
1 of 1 people found the following review helpful
5.0 out of 5 stars Ways of Seeing,
Rob Spence "Rob" (Manchester England) - See all my reviews
This review is from: Sightlines (Paperback)
I have long admired Jamie's poetry, but in the essay form, I think she has found her true métier. The previous volume of short prose pieces, Findings, was a delight from start to finish: Sightlines is better. Both titles give a clue as to what is contained within - these are essays of observation and reflection, mostly, but not completely, of the natural world. What strikes the reader is the originality of the observations, particularly of the relatively mundane. She has a knack of seeing things from a startlingly original perspective, and she is able to communicate that vision in clear, sinuous language that delights and entertains.
As well as the treatment of landscape, particularly of her native Scotland, the book chronicles Jamie's investigation into the strange landscapes of cell biology seen through a hospital microscope, the Aurora Borealis, and the sight of a group of killer whales on the hunt, as well as many more examples of the strange and the ordinary.
Her journey to Greenland, detailed in the first essay in the book, was occasioned by a carpe diem realisation that she had reached middle age without seeing an iceberg. Her account of the journey takes in both the natural beauty of the land- and seascape, as well as the trials of a rough sea voyage.
Possibly the most dramatic account in the book conncerns the sighting of killer whales off the coast of Rona, the island forty miles of the coast of Scotland, once inhabited, but now deserted, like St Kilda. In this essay, Jamie moves seamlessly from the ominous description of the whales' arrival to the almost slapstick scene where the members of the groups she is with run around the headland chasing the whales as they hug the coastline below in search of prey.
The book is a delight, the photographs complementing the vivid writing. Each essay leaves the reader feeling that something has been illuminated in a rare and poetic way. This will sit on my shelf next to George Mackay Brown, than which I have no higher praise.
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Sightlines by Kathleen Jamie (Paperback - 5 April 2012)
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Anti-racism forum in Portland
program date:Mon, 05/10/2010
Rose City Anti Fascists, the local chapter of Anti Racist Action, held a community forum on Saturday April 24th.
Panelists discussed the history of the white supremacy movement in Portland, recent violence, and how to respond as a community to fascist groups.
KBOO's Isobel Charle has more.
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subset: commoncrawl


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The company says the top sellers were HDTVs, the iPad Mini, notebooks, the new Xbox One and PS4 and Call of Duty Ghosts. Online, SLRs and the Nintendo 3DS were major sellers, as well.
Altogether, the company sold an incredible 1.4 million tablets.
safer? I guess they don't even read the news.
They used the comparative in their choice of words " safer "
Correct English grammar should be "safe". Same corporate liars, they left out safer than what?
well, tabs are devices of choice for most (read: ordinary) people and many intellectuals, anyway. if you are not associated with a corporate, and/or don't do rocket science, and/or don't need much power/functionality, tabs may be your choice over laptops.
I didn't buy any of that and I didn't even bother to go out for Black Friday, just shopped on-line: didn't care to wait in line.
People with good common sense don't need to wait 1 year for "Black-Friday" to shop wherever.
This is the ultimate corporate holidays brainwash "ads" milking the sheep's.
What is next: "Cyber Monday" and so on....
Walmart = Poverty for their employees (Paying minimum wage & not full time, to get away with insurance ...for them).
Walmart is on top of the worse corporations out there.
Comparing prices all year around is more easy online.
iOS users are more corporate brainwash sheep's that Android users:
Originally posted by dp70:
They used the comparative in their choice of words " safer "
Correct English grammar should be "safe". Same corporate liars, they left out safer than what?
Our Black Friday events were bigger, better, faster, cheaper and safer than ever.
Originally posted by nonoitall:FYI: Just so you know:
Originally posted by dp70:
.... safer than what?
.....safer than ever.
Oh, it wasn't my assertion by any means; I was just pointing out that the quote did in fact specify what this year was supposedly being compared to as "safer".
I think people are inhuman when it comes to Black Friday.
Safer means no one died this time
AC/DC will finally join streaming services including Spotify and Apple Music (29 Jun 2015 23:28)
AC/DC, one of the most notable bands to not be available on streaming services, is finally signing up.
Samsung wants to build more Tizen phones this year (29 Jun 2015 23:05)
Samsung has confirmed plans to build more handsets running its own Tizen operating system, with release scheduled for this year.
Here are the leaked design photos of the upcoming OnePlus 2 (29 Jun 2015 22:35)
Although OnePlus has been slowly releasing important tidbits about its upcoming OnePlus 2 flagship, there is still little known about the actual design. That is, until today.
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Apple to increase its iTunes Match cloud limit to 100,000 songs (29 Jun 2015 21:51)
Since its launch in 2011, Apple's iTunes Match service has allowed users to store 25,000 songs in their iCloud but it appears that that figure is set to increase significantly.
Apple Music will be available on Sonos speakers this year (29 Jun 2015 21:22)
Sonos users who were considering Apple Music based solely on what their speakers support should be happy as Apple has confirmed that the service will be available on Sonos speakers by the end of the year.


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Lenovo's IdeaPad S10 is described in the literature as an "affordable secondary PC," but the pitch quickly segues to addressing the "first-time PC user" and, finally and inexorably, "some mainstream consumers." It's a telling transition between what netbooks were supposed to be–geek toys–to what they really are–main machines for nontechnical users. It sums up a computing zeitgeist that few seem comfortable with. Among that few, however, is my 63 year-old mother-in-law, who is replacing a crappy old Dell laptop with a new 10.2" model. She doesn't even know that the new one is in a category that Intel insists she couldn't possibly want to use. Lenovo's new model is a pretty one, with the increasingly-ubiquitous Splashtop Linux: awake within seconds of the power switch being flicked, it offers browser, music player, instant messaging and Skype. Other new features include a multitouch trackpad and facial recognition software. The specs are otherwise standard fare, with a 10.2 display, Atom CPU and 1GB of RAM, just like all the others. It'll be available in March for a pleasantly modest $350.
Netbooks five: Lenovo's S10 brings the color wheel and instant-on Linux
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One Response to "Netbooks five: Lenovo's S10 brings the color wheel and instant-on Linux"
Hmm, two more colors or built-in Bluetooth like they do in Asian models (and publicly spec'ed on the US models but never delivered.) Which is more important…?


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About FaxBack:
One of the early pioneers in fax, FaxBack has developed fax solutions for the world's technology and telecom leaders including Western Union, Intel, Microsoft, AT&T, ITT WorldCom, Symantec, Dialogic, IBM, and many of the world's leading companies. FaxBack is the outright VoIP Fax leader for the single user and large scale carrier respectively. FaxBack provides a single source for T.30, T.38 and SIP stack work with the widest variety of VoIP gateways, fax servers, and fax machines. FaxBack's VoIP fax driver, utilized in its small business, enterprise and carrier solutions, is a key strategic component of FaxBack's industry leadership. For more information, please visit www.faxback.com.
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I am wanting to upload a csv file, validate it, and then upload into an existing model. However, I am using ATK4.2.1 and finding that either the example code that have googled are either missing some steps or not relevant in version 4.2.1.
To this end, for my first step I have tried mixing and matching code in attempt to get a fileStore up and running with no working results thus far.
Is there a step by step tutorial/guide that anyone can point me to. The reference on the agiletoolkit.org site does not have any examples for the atk4-addons; that I can find. It seems that it is more involved than just adding an object to the page.
Grateful for any assistance.


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"The brain is a wonderful organ. It starts working the moment you get up in the morning and does not stop until you get into the office." - Robert Frost
Welcome to the Brain@McGill
As you read this, your brain is completing millions of necessary transactions to keep you alive and allow you to understand the world around you. If the workings of the brain fascinate you, there are few better places to be today than right here in Montreal.
You could say the brain is at home in McGill!!
The Brain@McGill brings a contemporary focus to decades of distinguished work in neuroscience. It will consolidate the research and study opportunities among a dozen key institutes within the McGill University network and with our partners around the world.
In 2009, we were joined by the University of Oxford in a formal collaboration between the two Faculties of Medicine. Since then, we have been delighted to welcome Imperial College London, and the Neuroscience Center of Zurich also as partners.
The brain is at the very core of human activity and these are exciting times in neuroscience. Just a few recent examples:
- Our colleagues at the Montreal Neurological Institute are closing in on an early diagnosis of Alzheimer's and Parkinson's Disease.
- The Douglas Institute is home to the McGill Group for Suicide Studies -- unique in Canada and one of the only programs of its kind in the world – which is helping us to understand what puts people at risk for suicide.
- The Integrated Program in Neuroscience at McGill has created a world-leading hub, including one of the largest neuroscience graduate programs in North America.
The Brain@McGill is not confined to the lab. Our research finds many applications in the cultural and economic domains and we hope to reach out to the general public and raise awareness of our most fascinating discoveries.
Whether you are a researcher, a graduate or post-graduate student, a partner, or you just have a fierce curiosity about the human brain and nervous system, I welcome you and hope The Brain@McGill becomes a part of your life, as it is ours.
Dr. Claudio Cuello,
Chair of the Brain@McGill Committee,
McGill University


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SJBP Summer Technology PD
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World Link of Churches & Ministries Presents, "Spirit of Pentecost Conference 2013"
World Link of Churches & Ministries, Inc.
Daily Event - Every 3 days: 7:00 PM to 9:30 PM (PDT)
Gonzales, LA
World Link of Churches & Ministries Presents "The Spirit of Pentecost Conference", July 14th-19th at 7:00 p.m. and 12noon services, held at Life Cathedral Worship Center, 2103 S. Philippe Ave, Gonzales, LA. Prepare for a conference that will revolutionize your entire life! This conference is FREE to the public and everyone is invited. Experience an unforgettable week of MIRACLES, HEALING, praise and worship! On Saturday, July 20th, meet us at the steps of the State Capitol downtown Baton Rouge at 8:00-11:00 a.m., as we PRAY for DIVINE PROTECTION for the State of Louisiana.
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Phone: 225-291-2400
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Email: firstname.lastname@example.com
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Barbie's careers through the years
It's been 56 years since Barbie debuted at the International American Toy Fair in New York. The iconic doll is arguably one of the most classic toys for kids. And boy has she been busy! Here we take a look at Barbie's careers from 1959 through today.
15 things you need to buy for Shark Week Your pet photos: Adorable dogs, cats and more Puppies from Sweetest Dog Rescue Nathan's hot dog eating contest, more NYC weekend picks New rides at nearby amusement parks Peek into Long Island's most lavish homes Summery cocktails for July Fourth Nordstrom, Macy's, more sales this weekend 45 LI dogs you can adopt right now Animals around the world Hallmark's Paw Star Game: Cats at bat 20 stylish Fourth of July fashions


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GeneChaser: Identifying all biological and clinical conditions in which genes of interest are differentially expressed
1 Stanford Center for Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, 251 Campus Drive, Stanford, CA 94305, USA
2 Department of Pediatrics, Stanford University School of Medicine, 251 Campus Drive, Stanford, CA 94305, USA
3 Lucile Packard Children's Hospital, 725 Welch Road, Palo Alto, CA 94304, USA
4 Optra Systems Pvt. Ltd, 1, "Dnyanesh", CTS No. 1179/3, Modern College Road, Shivajinagar, Pune, 411 005, India
BMC Bioinformatics 2008, 9:548 doi:10.1186/1471-2105-9-548Published: 18 December 2008
The amount of gene expression data in the public repositories, such as NCBI Gene Expression Omnibus (GEO) has grown exponentially, and provides a gold mine for bioinformaticians, but has not been easily accessible by biologists and clinicians.
We developed an automated approach to annotate and analyze all GEO data sets, including 1,515 GEO data sets from 231 microarray types across 42 species, and performed 12,658 group versus group comparisons of 24 GEO-specified types. We then built GeneChaser, a web server that enables biologists and clinicians without bioinformatics skills to easily identify biological and clinical conditions in which a gene or set of genes was differentially expressed. GeneChaser displays these conditions in graphs, gives statistical comparisons, allows sort/filter functions and provides access to the original studies.
We performed a single gene search for Nanog and a multiple gene search for Nanog, Oct4, Sox2 and LIN28, confirmed their roles in embryonic stem cell development, identified several drugs that regulate their expression, and suggested their potential roles in sex determination, abnormal sperm morphology, malaria infection, and cancer.
We demonstrated that GeneChaser is a powerful tool to elucidate information on function, transcriptional regulation, drug-response and clinical implications for genes of interest.


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Name: WLMMA
Title: We Love MMA 5
Date: Mar 16, 2013
Location: Universal Hall, Berlin, Germany
Organization: Free Fight Association Germany
Watch Rashid Magomedov's win over Elias Silverio at UFC Fight Night. watch video >>
Aleksander Emelianenko vs. Ibragim Magomedov M-1 Challenge 33Dzheirakh, Russia, RussiJune 6, 2012 watch video >>
Superior FC präsentiert M-1 Fighter Europe: Abus Magomedov vs. Gocha Smoyan. watch video >>
Giorgio Petrosyan vs. Arslan Magomedov: K-1 Italy Oktagon 2007 watch video >>
Alexander Volkov vs Ibragim Magomedov -M-1 Selection (pt 1) watch video >>
Rashid Magomedov Finishes Elias Silverio UFC Fight Night 58 Barueri view gif >>


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The Abbey Group and some students from Barre Town School help us prepare an eggs breakfast.
A smoothie may seem the opposite of what you crave in the winter but for the kids at Barre Town Middle and Elementary School it's what they crave every Thursday.
In cities and towns across the state, you see public safety organizations, but what are the perks of combining the resources from neighboring towns?
Supporters of a new bike path say it's key to connecting several bike paths in central Vermont towns but opponents say they don't want it running through their backyard.


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The Australian ballet celebrates its 50th anniversary with a Gala of international guests. Carmen Suite (excerpt) by The Tokyo Ballet. Photo: Angela Wylie
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The best pictures from the international wire services as chosen by the Picture Editors at the Sydney Morning Herald. Follow us at ...
Some of the planet's weirdest looking creatures were on display at the 27th annual World's Ugliest Dog competition in Petaluma, California ...
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- The Big Picture: What's AAP
- A year later, the tweak: Desh to Dilli
- Bus from Burari laden with volunteers and hope
- Rare day out for AAP families
- Riot of support for AAP in communal hot spots
- Hunt on for CM house, will not accept Z-plus security
- No word from high command, Delhi Congress in a paralysis
- Latest News
- Second time at Ramlila Maidan: Hope overrides their doubts
- Kejriwal has no portfolio, will keep an eye on others
- In sea of white caps, BJP troika plans to be 'forceful opposition'
- MP, MLA see Punjab as the next AAP stop
- A year later, the tweak: Desh to Dilli
- Arvind Kejriwal repeats his advice to sting the corrupt, asks police to act against 'goondagardi'
- Proud that one of our volunteers has become Delhi CM: Anna Hazare
- Arvind Kejriwal not to keep any portfolio
- Now an Aam Aadmi Party Cola by beverage-maker inspired by Arvind Kejriwal's party
- New chief minister Arvind Kejriwal holds meetings at Delhi Secretariat
- Cong's Ajay Maken blames Sheila Dikshit for Delhi polls debacle
- Left, right, AAP
This way to Delhi: From RSS pracharak to PM-designate, Narendra Modi has come a long way
In August 2011, Narendra Modi had called up his friend in London and asked him, "So tell me, are the London riots still on?" "Yes," the young friend replied. The riots had broken out on August 5, 2011, and lasted nearly a week. "Then why am I being targeted," Modi is said to have asked this friend, who spoke to The Sunday Express on condition of anonymity.
If Modi was indeed anguished then, he bounced back fast. A month later, the Supreme Court said it would not monitor the case filed against him by Zakia Jafri, the widow of riot victim and former MP Ehsan Jafri, and Modi announced his Sadbhavana Mission, a series of fasts that were to be his bid to reach out to minorities. During his fast inside the airconditioned Gujarat University Convention Centre, as Narendra Modi posed for photographs with burqa-clad Muslim women, outside, BJP women members sat with foolscap notebooks, running a signature campaign for 'Modi as PM'.
A top BJP leader says, "Though whispers that Modi was in the prime ministerial race began in the corridors of the Chief Minister's Office as early as January 2008, a couple of weeks after Modi won his second term, it was only after the Supreme Court-appointed SIT gave him a clean chit in the riot cases when that it picked pace."
Modi then got down to revamping the machinery around him — largely independent of the BJP — and reinvented his own image from that of 'Hindu Hriday Samrat' to that of an investor-friendly CEO-CM of a 'progressive state', whose government was 'inclusive' and 'development-driven'.
In December 2011, Modi spotted Prashant Kishor, a 36-year-old former UN Mission Chief in Africa and roped him into his core team. Kishor, who is from Bihar, fit into Modi's need for a technocrat who would help him reach out to hostile political terrains such as Bihar. Kishor founded the NGO Citizens for Accountable Governance (CAG) and gave a youthful touch to the Modi campaign by bringing in an army of IIT and IIM graduates who quit plush MNC jobs to join the Modi backroom.
Apart from conventions to connect with the youth, CAG helped organise Chai pe Charcha programmes across the country to firmly found Modi's beginnings as a "tea vendor".
As part of the plan, Modi retained his trusted bureaucrat Kuniyil Kailashnathan (popularly called KK) after he retired last year by appointing him principal chief secretary in the CMO to look after the administrative affairs of the government. KK had been rewarded for playing a key part in Modi's image-building exercise. KK's role for more than seven years in the CMO had been to bring the government and industry together. He was the man in charge of the Vibrant Gujarat Global Investor Summit (VGGIS), Modi's flagship event that …continued »


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Duke mulling Kyrie Irving's options
Updated: December 10, 2010, 11:27 AM ETBy Andy Katz | ESPN.com
Duke is reviewing all its medical options during the next few weeks before making a final decision, in conjunction with star freshman Kyrie Irving and his family, about whether the point guard's season is over because of ligament damage in his right toe.
Multiple sources with knowledge of the situation said Thursday that Duke is exploring various courses of action, from surgery to rest to other forms of treatment for the freak injury that Irving suffered in the second half against ...
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Can We Replace Our Skulls?
Cases for mobile phones are one of the most common purchases made when getting a new phone. This makes perfect sense because it is very important to protect the phone. After all, it holds a lot of important information and allows the user to do a myriad of things at a moment's notice. Well, similarly our brain is very important and nature's well designed case for it, the skull, plays a very important protective role.


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|Search | About | Preferences | Interact | Help
|Find any book at the best price.
by Hamilton, Robert W.
Publisher:West Group
A number of changes in this edition reflect new developments such as changes in many large law firms due to major increases in entry level salaries for associates; important revisions in the Model Business Corporation Act; recent developments in asset-protection of limited liability companies; two important decisions in Delaware on the duties and liabilities of directors of publicly held companies; the enactment of the Securities Litigation Uniform Securities Act (SLUSA); the adoption of new regulations, Rule 10b-5-1 and 10b-5-2; and adoption of new regulations relating to full disclosure by registered publicly held companies (Regulation FD) and the independence of auditors.
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Student StoragePosted on May 1, 2015Limited storage is available for students who will be away from campus in the Spring Semester. More »
End of Year Closing InformationPosted on May 1, 2015All residence halls and houses close on Saturday, May 9th, at 8 p.m. All students are expected to vacate their hall or house 24 hours after their last exam or by 8 p.m. on the 10th (whichever comes first). No unapproved exceptions. More »
Summer WaitlistPosted on April 29, 2015A.K.A. the "Summer Lottery". Click here for information. More »
Summer Housing ApplicationsPosted on April 1, 2015Information on Summer Housing and Applications are available now. More »
Room PaintingPosted on August 25, 2012Painting request forms are now available online. Click for details. More »
Rental Services for YouPosted on August 7, 2012We have partnered with these third-party companies to help improve your quality of life on campus. More »


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product details-Tab
Toothbrush for Children Ages 5 – 7
At Stage 3 of their evolving oral health, kids brushing from ages 5 – 7 will be losing some baby teeth as their molars start to grow. It's the perfect time to teach them how to brush their teeth properly as they begin to understand what makes for the best brushing habits. Oral-B® Pro-Health Stages® Monsters, Inc. Manual Kid's Toothbrush surrounds and cleans their pearly whites and helps them reach tricky back teeth while protecting tender gums. The shape is perfect for little hands and small mouths, giving them a thorough clean even if their technique is anything but.
Characters may vary.
Made in USA
Do not chew or bite on brush. Do not use as a toy or without adult supervision.
©Procter & Gamble
(based on 1 review)
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(0 of 4 customers found this review helpful)
bad product
By Evelina
from NY
See all my reviews
Comments about Oral-B Pro-Health Stages Monsters, Inc. Manual Kid's Toothbrush, 1 ea:
I threw away this toothbrush after 1 week of using. This was shortest life of my son's toothbrush.
Bottom Line No, I would not recommend this to a friend
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Replace brush every 3 months, or sooner if brush head looks worn.


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The 2015 Championship promotion playoffs final is set for May 25, when Middlesbrough and Norwich City are set to do battle at Wembley Stadium with a place in the 2015-16 Premier League on the line. 264 more words
Tags » Nathan Redmond
Woeful Wigan Display: Five Things We Learnt
Our winning run came to an abrupt end last night as Malky Mackay's Wigan Athletic showed they still have some fight left in them as they attempt to avoid the drop. 766 more words
Big Match Review: Watford 0 City 3
Alex Neil once again showed his tactical awareness after initial questions were raised over his team selection prior to today's impressive 3-0 win over fellow promotion contenders Watford. 634 more words
Big Match Preview: City vs Watford
Tomorrow, our away form which has seen us lose only once on the road since early November comes up against a free-scoring Watford side possessing a potent attacking force, in what Alex Neil expects to be a "fiercely contested" encounter. 464 more words
Liverpool Line Up £47m Triple January Raid - reports
Liverpool are lining up a £47 million triple January raid in a bid to fix their broken season, as reported by the Daily Star. 135 more words
Redmond Rumours
Writer: @adamlovlallana
Liverpool are preparing a £10m swoop for highly rated U21 star Nathan Redmond from Norwich City.
Brendan Rodgers is a keen admirer of the winger and clearly believes Redmond can have a similar impact as Raheem Sterling. 196 more words


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Mets unlikely to call up prospect Noah Syndergaard
Aug 11, 2014, 1:50 PM EDT
Mets right-hander Noah Syndergaard is one of the best pitching prospects in baseball and he's racked up 111 strikeouts in 108 innings at Triple-A as a 21-year-old, but Adam Rubin of ESPN New York reports that he's unlikely to be called up to the majors this season.
According to Rubin there hasn't been an official decision made yet regarding his potential debut, but the Mets' Triple-A team is bound for the playoffs and Syndergaard may surpass his team-imposed workload limit during the postseason run.
It's possible he could get a September call-up and a few relief appearances, but given his age and minor arm problems earlier this season Syndergaard making a full-scale debut as a member of the starting rotation seems like a long shot.
- jets82jets - Aug 11, 2014 at 3:35 PM
Well I'm a Mets fan and I'd much rather him get a little major league experience for next year rather than the Las Vegas 51's winning a triple A playoff title that doesn't mean anything.
- asimonetti88 - Aug 11, 2014 at 3:41 PM
The Mets are going to have a crazy good rotation very soon here, with Harvey and Wheeler and Snydergaard…
- anthonyverna - Aug 11, 2014 at 5:10 PM
And, of course, no MLB team wants to start the clock ticking.
Top Posts
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- Settling the Score: Saturday's results 38
- Video: Kris Bryant hits a grand slam as part of a two-homer, six-RBI night 8
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Madison Avenue
Commute to Downtown Memphis
Most errands can be accomplished on foot.
Flat as a pancake, minimal bike lanes.
Score Details
Madison Avenue has a Walk Score of 87 out of 100. This location is Very Walkable so most errands can be accomplished on foot.
This location is in the Downtown neighborhood in Memphis. Nearby parks include Court Square, Town Square and Handy Park.
Explore how far you can travel by car, bus, bike and foot from Madison Avenue.
Madison Avenue is in the Downtown neighborhood. Downtown is the most walkable neighborhood in Memphis with a neighborhood Walk Score of 52.
Moving to Memphis from another city? View our moving to Memphis guide.


text: The 2011 NEA Jazz Masters. Top row (L-R, from second left): Delfeayo Marsalis, Branford Marsalis, Ellis Marsalis, Wynton Marsalis, Jason Marsalis. Bottom row (L-R): Hubert Laws, Orrin Keepnews, Johnny Mandel, David Liebman. Also pictured are NEA Chairman Rocco Landesman (top row, left), NEA Director of Music and Opera Wayne Brown (top row, right), and Executive Director of Jazz at Lincoln Center Adrian Ellis (bottom row, right). Frank Stewart/Jazz at Lincoln Center/NEA hide caption itoggle caption Frank Stewart/Jazz at Lincoln Center/NEA Concerts The 2011 NEA Jazz Masters Awards Concert WBGO-FM January 11, 2011 In a ceremony held Tuesday at Jazz at Lincoln Center in New York, the National Endowment for the Arts presented the country's highest awards for jazz artistry and advocacy. Hear a recording of the entire event, featuring the Jazz at Lincoln Center Orchestra. Listen Loading… 1:53:52 Playlist Embed Embed Close embed modal <iframe src="http://www.npr.org/player/embed/132738102/132887282" width="100%" height="290" frameborder="0" scrolling="no">


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Technical Summit 2014 by medialesson GmbH Offizielle App zum Microsoft Technical Summit 2014 in Berlin Funktionen der App: - Aktuelle Agenda - Eigene Agenda zus … 100+ downloads, Rating 3.33 (6) Free
Round One Timer by Red Hot Projects Professional style boxing round counter. Simple and effective application for interval training. Rounds are counted as … 10,000+ downloads, Rating 4.15 (254) Free
250+ Solitaire Collection Updated by Alexei Anoshenko "250+ Solitaire Collection" is a collection of 253 solitaire games. The collection contains favorite solitaire games suc … 5,000,000+ downloads, Rating 4.40 (59153) Free
예든아이어린이집 by KNsoft co,.Ltd 예든아이 어린이집 어플리케이션입니다. Recent changes: 사진3개이상 업로드기능 추가 원장님권환으로 홈페이지 접속또는 휴대폰앱 실행 후 설정 - 프로필 - 홈페이지주소 클릭으로 게시판관리 들어가시 … 10+ downloads, Rating 0.00 (0) Free
Pharaon Bubble Shooter by awe Pharaon Bubble Shooter is a very fun and addictive bubble shooting game. You need to eliminate all bubbles by using as … 100+ downloads, Rating 4.83 (6) Free
Recetas de Mamá by Welbits La aplicación ideal para aprender recetas nuevas y sorprender a tu familia o amigos. Un conjunto de recetas sin complica … 500+ downloads, Rating 5.00 (12) Free
Puzzle Me 1 by MyFirstApp Ltd. - Learning Games for Kids Puzzle fun for puzzle beginners. Enjoy this clear, bright, colorful collection of square puzzles. Puzzle-Me helps devel … 1,000+ downloads, Rating 4.50 (10) Free
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Dogfight by Creative Canvas Cmp Fight your way through the enemy planes, vessels and boss planes. Complete each wave of army to tackle next tougher wave … 1,000+ downloads, Rating 4.13 (23)


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Macau gallops on
Most Popular
Since betting on Macau horse-racing by both telephone and the Internet is outlawed in Hong Kong, may I ask why ATV World continues to devote three nights of primetime television each week to it? Despite being effectively outlawed, it seems paradoxical that far more broadcasting time (Friday, Saturday and Sunday: 8.30pm-11.33pm) is dedicated to Macau Racing than any other topic.
Additionally puzzling is that ATV chooses to screen nine hours of Macau Racing a week exclusively on its English-language channel.
Since horse-racing in Macau does not merit any coverage whatsoever on ATV's Chinese-language channel, ATV Home, one clear inference is that only English-speaking audiences are intent on defying the new Hong Kong law.
Sai Kung
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Today is the 233rd birthday of the U.S. Marine Corps.
It is also the third anniversary of the opening of the National Museum of the Marine Corps.
We talk to the museum's director, Lin Ezell, who tells us that the museum is sponsored by the Marine Corps. Click to hear the interview.
How the US Mint and NIST are perfecting the money-making process.


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Your Starion community is Bismarck. Change?
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Insurance Request Coverage Change
Quickly and conveniently submit policy changes by filling out the online form below. After we review your request, we'll contact you directly to confirm the change, or to get any additional needed information. If you prefer, you can also contact your Starion Insurance agent directly.
The following form allows you to submit changes or requests on your existing policies. Please note that this form will not automatically alter your policy, but will be sent to an agent for review.
Starion Financial will use the information you provide to adjust your coverage as you specify only after we confirm your changes are valid. We will not share this information except as specified by the Starion Financial Privacy Policy.
Insurance products are: * Not a deposit * Not FDIC insured * Not insured by any federal government agency * Not financial institution guaranteed
Starion Financial's Heck joins Risk Management
Jenny Heck has taken a new role at Starion Financial as a compliance specialist in the risk management department.
Wed. Jul 01 3:07 PM
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Starion Financial promotes, hires in Mandan
Starion Financial has promoted three employees and hired two, all at the Mandan branch.
Starion Financial adds to management committee, announces promotions
Starion Financial has announced promotions and added a member to its management committee.
Thu. Jun 25 9:06 PM
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Starion Financial named to Top 10 Young Professional Workplaces
Starion Financial was presented with a Top 10 Young Professional Workplaces award by the Bismarck-Mandan Young Professionals Network.
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Starion Financial named a top-performing community bank in the nation
Starion Financial was named to "The Best of the Best" list by Independent Banker magazine and received a superior rating from BauerFinancial.
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Starion Financial awards scholarships to Brenden, Leas, Nadeau
Starion Financial awarded the Starion Community All-Star Scholarships to area high school seniors Stephanie Brenden, Logan Leas and James Nadeau.
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St. Peter's, Rome
- Free WiFi
Main amenities
- 9 apartments
- Self parking
- Airport shuttle
- Air conditioning
- Multilingual staff
- Limited hour front desk
What's around
- In Vatican
- St. Peter's Basilica (0.4 mi / 0.7 km)
- Sistine Chapel (0.6 mi / 1 km)
Enter dates to check prices
Hotel Info: 020 3027 9803from £89
- Double Room
- Triple Room
- Studio, Kitchen
Recommended hotels
At a glance
Key facts
Hotel size
- This hotel has 9 rooms
- This hotel is arranged over 1 floor
- Check-in time 11 AM-8 PM
- Check-out time is 10 AM
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- No pets or service animals allowed
Extra people
- Rollaway beds available, charges may apply*
- Free WiFi in public areas
- Free WiFi in rooms
- Airport shuttle *
- Self parking *
- Discounted offsite parking
- RV/bus/truck parking *
Nearby One Star Rome hotels
In the hotel
- Front desk (limited hours)
- Number of buildings/towers - 1
In the room
- Climate control
- Air conditioning
- Hair dryer
- Flat-screen TV
- Free WiFi
Top Rome hotels
Recently reviewed hotels in Rome
- Leon's Place HotelFrom
- Confort B&BFrom
"Excellent location the staff was fantastic. I really enjoyed my stay here."Jun 22, 2015
- Hotel Appia 442From
"A perfectly fine 1 night stay in a small but modern room with a little balcony. It was quiet and comfortable, spotlessly clean and had a decent shower. Staff were polite, gentle…"Jun 22, 2015
- ArcangeloFrom
"I had 1.5 days to spend in Rome before the start of a business trip. I'm glad I found this hotel thanks to previous reviews. The Arcangelo Hotel has cosy rooms (I used a small one…"Jun 22, 2015
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St. Peter's, Rome's small print
Cash transactions at this property cannot exceed EUR 999.99, due to national regulations. For further details, please contact the property using information in the booking confirmation.
Mandatory fees
You'll be asked to pay the following charges at check in or check out:
- A tax is imposed by the city: EUR 3.5 per person, per night. This tax does not apply to children under 10 years of age.
Optional extras
Late check-in between 8:30 PM and Midnight can be arranged for an extra charge (amount varies)
Parking is available nearby and costs EUR 20 per 24 hours
Airport shuttle service is offered for an extra charge of EUR 55 per vehicle (one way)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.


text:
Interactive Seating Charts
Unfortunately, we do not currently have
a seating chart for Neal S Blaisdell Concert Hall.
Neal S Blaisdell Concert Hall777 Ward Avenue
Honolulu, HI 96814
Upcoming Events
Jul 10
Fri 7:00 PM
Jul 11
Sat 10:30 AM
Jul 11
Sat 2:00 PM
Jul 11
Sat 5:30 PM
Jul 12
Sun 10:30 AM
About Seatgeek
We scour the web's major ticket sites and aggregate inventory into one place. Our Deal Score helps you identify the best ticket deals available for each event.Learn more about SeatGeek


text:
I am trying to setup a custom SOAP fault code in wso2/wsf php framework. The instructions in relevant posts that say to use something like this:
throw new WSFault("CustomFaultCode", "CustomFaultDescription");
do not work (php timeouts and I get a website not available warning). The first thing that i did was to change it to:
static $ex; $ex = new WSFault("Sender", "CustomFaultDescription."); throw $ex;
and this works, but only if I use default SOAP fault codes (like Sender), not custom fault codes. I suppose that I have to make changes to the WSDL as well. What could you suggest?
Thanx a lot in advance!


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Check out our new look @ afterschoolalliance.org
Last week, we rolled out a new look at afterschoolalliance.org. Don't worry, all the resources you've come to expect on policy, research, advocacy, funding and communications are still here – but in a new and improved format.
We've worked hard to make it easier to find the information you need, with brand new search features to make our best research more accessible and a revamped Afterschool Toolbox full of practical tools to strengthen (or start!) a program. We've also added new visuals to make your visits to our site more enjoyable.
There will be a few hiccups here and there during this transition. We thank you in advance for your patience. If you notice something awry while you're exploring, post a comment or drop us a line at firstname.lastname@example.com so we can address it right away.
We hope you enjoy surfing around the new afterschoolalliance.org, and we want to hear from you! Do let us know what you think in the comments section below, and provide any suggestions you have for our site. We will be rolling out more improvements throughout the summer!
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Afterschool policy advancing in state legislatures nationwide
While Congress continues to struggle to pass federal spending and policy changes advancing afterschool and summer learning programs, advocates have been busy building support for local and state efforts to expand access to quality afterschool and summer learning programs. From Vermont to California, friends of afterschool coordinated by Statewide Afterschool Networks have succeeded in fighting back cuts and laying the groundwork for new investments in out of school programming that keep young people safe, help working families and inspire learning. Below are a few highlights of them many actions taking place at the state level.
Vermont Governor Peter Shumlin recently signed H. 480, a Miscellaneous Education bill, into law as Act 48. The Act, supported by Vermont Afterschool inc., established the Expanded Learning Opportunities Special Fund at the Vermont Agency of Education. No money was budgeted for the new fund but having it established means the state can start raising money for Expanded Learning Opportunities through grants, donations and contributions. Read more on the Vermont Afterschool blog.
Early this month Baltimore Mayor Stephanie Rawlings-Blake began fulfilling her campaign promise to double afterschool funding by announcing $4.7 million in additional funds for afterschool programs in the city. The Maryland Out of School Time Network worked closely with a number of state and local partners to build support for the funding. These funds will support community based organizations including Associated Black Charities, the Family League of Baltimore and the Baltimore City Community Schools' afterschool initiatives. Rawlings-Blake stated the recent uptick in violence in the city following the death of Freddie Gray in police custody makes investing in young people and keeping them safe in the hours after school more important than ever. Read more on the Baltimore Sun website.
learn more about: State Policy
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FY16 appropriations update: Urge Congress to support afterschool and summer learning programs
This has been a busy week for House and Senate Appropriations Committees. Quick on the heels of the House Labor, Health and Human Services, Education (LHHS) Appropriations Subcommittee mark-up of their FY2015 spending bill last week, the equivalent subcommittee in the Senate marked up their own version of the bill that sets funding levels for all federal education, human service, health and labor programs. The full Appropriations Committee in the House and Senate followed next, passing their respective bills on straight partisan votes Wednesday and Thursday this week.
Due to tight spending caps set earlier this year, both bills include significant cuts to education and other programs that provide necessary supports to children and working families. With regard to key federal efforts that support afterschool and summer learning programs provided by local school-community partnerships, the House LHHS bill funds the 21st Century Community Learning Centers (21st CCLC) initiative at the FY2015 level of $1.152 billion, while the Senate bill cuts 21st CCLC by $117 million, about 10 percent of current funding levels. If the Senate bill were to become law, between 117,000 and 175,000 children would lose access to quality afterschool and summer learning programs next year.
The Senate LHHS bill proposes to fund the U.S. Department of Education and its federal education programs to the tune of $65.5 billion, a $1.7 billion cut from FY2015. Both bills also eliminate a number of key education programs, with more than 20 programs getting the axe in the House bill and ten meeting the same fate in the Senate bill, including Investing in Innovation, Carol M. White PEP grants and the Striving Readers Comprehensive Literacy Program.
In addition to the cut to 21st CCLC, the Senate bill decreases funding levels for School Improvement Grants by $56 million and Promise Neighborhoods by $20 million. Increases are proposed for Title I for low-income students which can be used to provide afterschool and summer learning programs ($150 million increase), the Individuals with Disabilities Education Act ($125 million increase) and charter schools ($20 million increase). With regard to non-education programs that support afterschool programs for children, the bill increases the Child Care Development Block Grant (CCDBG) by $150 million, but cuts AmeriCorps funding by 20 percent. Some key differences between the House and Senate LHHS bills are listed below:
learn more about: 21st CCLC Budget Congress Federal Funding Federal Policy Legislation
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Social-emotional learning heats up
By Jen Rinehart
Along with the soaring temperatures of summer, June brought a focus on the importance of social-emotional learning and the role of afterschool in supporting skills and mindsets like collaboration, responsible decision making, problem solving, citizenship and resilience.
The Afterschool Alliance participated in a convening led by the National Afterschool Association in mid-June that focused on the landscape of social-emotional learning in afterschool and summer programs and how the afterschool field can better articulate its important role in supporting social-emotional learning.
It was an inspiring conversation, with several national providers highlighting their efforts in this area and researchers highlighting the growing evidence base showing how critical social-emotional learning is for youth success.
That meeting was followed by the release of The Wallace Foundation-funded Foundations for Young Adult Success: A Developmental Framework, which makes a research-driven case that successful youth development requires both academic and social-emotional learning. It illustrates how learning is shaped by children's interactions with the world and the adults around them, and how they make meaning of their experiences.
With the social-emotional learning conversation heating up, now is a great time for afterschool providers to tell their social-emotional learning story—how do you support social-emotional learning in your afterschool and summer program and what help do you need in order to keep up that work and to talk to stakeholders about the importance of social-emotional learning?
You can be a part of the social-emotional learning conversation today by completing this brief survey. As a thank you for your time, you'll be entered to win one of four $50 Amazon gift cards.
learn more about: Events and Briefings Youth Development
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Learning and development: It's academic and much more
By Jen Rinehart
A new Wallace Foundation funded report, Foundations for Young Adult Success: A Developmental Framework, pulls together decades of research from across a number of fields to illustrate that children need more than academic knowledge alone to succeed in life.
The developmental framework highlights four foundational components – (1) self-regulation, (2) knowledge and skills, (3) mindsets and (4) values – and describes how these components are essential to success and are shaped by each young person's developmental experiences and relationships in multiple settings, including home, school and organized activities, like afterschool and summer learning programs.
The report also emphasizes how the foundational components interact to affect learning and development and how ineffective it is to target only one component in isolation. As a former teacher with a master's degree in human development and a long history of working in the afterschool field, I was especially drawn to this excerpt highlighting how a narrow focus on content knowledge in isolation actually undermines learning and development:
learn more about: Youth Development
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Weekly Media Roundup June 24, 2015
By Luci Manning
Louisiana Afterschool Programs Not Meeting Demand, Survey Says (Alexandria Town Talk, Louisiana)
Parents across Louisiana are having trouble finding afterschool and summer learning programs for their kids, according to the Afterschool Alliance's America After 3PM survey. By extending the day during the school year and into the summer, quality programs supplement what schools already provide and help augment student learning, United Way of Central Louisiana president and CEO David Britt said. Many area programs are already doing a good job, but Louisiana needs more high-quality programs to meet demand. "The community has got to step up and help," Britt told the Alexandria Town Talk. "There's more the community can do to align learning with what schools already are doing and have a big impact on student learning."
Valley Organization Connects Families with Affordable Summer Camps (KPHO, Arizona)
With summer camp season in full swing, many parents are struggling to find places for their children to spend summer vacation. "We see far more families expressing interest in having their children enrolled in summer programs than are actually able to participate now," Afterschool Alliance vice president of research and policy Jen Rinehart told KPHO. To fill the gap, groups like the Arizona Center for Afterschool Excellence are working to place children in affordable summer learning programs that provide a safe place, positive relationships and learning opportunities.
Letter: Summer Learning Is Important (Walla Walla Union-Bulletin, Washington)
Afterschool Ambassador Brent Cummings penned a letter to the editor of the Walla Walla Union-Bulletin touting the benefits of local summer learning programs: "At Walla Walla Public Schools' 21st Century summer programs, children get a heavy dose of exercise for both the mind and brain, giving kids opportunities for fun, interactive learning such as robotics camps, building drones and quad-copters, creating movies and TV shows, programming and testing self-created video games, and designing and 3-D printing board game pieces…. On behalf of all our students and their families, please spread the word about the importance of high quality, accessible summer learning programs."
Letter: Summer Fun Benefits (Kansas City Star, Missouri)
Afterschool Ambassador Kim Chappelow-Lee wrote a letter to the editor of the Kansas City Star about how her summer learning program improves students' physical health and academic abilities: "Keeping minds and bodies engaged during the summer goes a long way toward avoiding what researchers call summer learning loss…. At the Johnson County Park & Recreation District, children get plenty of exercise, which fuels both body and brain, along with opportunities for fun interactive learning, including: STEAM (science, technology, engineering, arts and math), gardening, field trips, community service, environmental education, social interaction and lots of fresh air. Unfortunately, there just aren't enough programs to go around."
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Project Play: A playbook to get every kid in the game
Project Play, a report and initiative created by the Robert Wood Johnson Foundation, the Aspen Institute, and other advocates for children's health, explores ways to engage more kids in physical activity. "A playbook to get every kid in the game," Project Play provides ways that communities can come together to fight the decline of kids' participation in sports.
The National PTA Conference, taking place this Friday in Charlotte, North Carolina, offers a perfect opportunity to share the problem addressed and the tools suggested in the Project Play report with parents, teachers, and other friends of afterschool. The report finds that fewer than half of children ages 6 to 11 are engaging in the recommended 60 minutes of activity each day, in part due to a decline in participation in team sports. Project Play finds that household income is the largest determinant of a child's access and participation in programs – children living in low-income households are about half as likely to participate in sports as children from wealthier homes, the report finds. Afterschool programs help to fill that gap and keep all kids active through play. On a typical day in an afterschool program, 67 percent of kids are physically active for 30+ minutes. Project Play aims to make 100 percent of kids able, confident, and wanting to be active by age 12, and everyone is a part of their strategy.
- For parents: Join a local sport board and promote inclusive policies to increase all kids' access. Support your local afterschool programs, where children can learn and play sports in a fun, non-competitive environment.
- For teachers and administrators: Commit to providing recess and daily physical education, and explore expanding access to intramurals and alternative sports. Grow efforts to open up your facilities during the non-school hours to community sport groups.
- For other friends of afterschool: Advocate in your communities for open play time in gyms and fields, and turn the space over to kids. Donate your time and skills to help afterschool programs provide quality physical education and inclusive sports playing.
Afterschool plays a major role in keeping kids active. Let's bring parents, teachers, and all other community leaders together to help America's kids become active for life.
learn more about: Health and Wellness
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Afterschool programs help Dad every weekday afternoon
Father's Day yesterday gave us all a special opportunity to tell our dads how important they are to us and how grateful we are for all they do. Dads often put in 110% for their kids, rushing to get them to school, to soccer practice, to Grandpa's, to birthday parties… while also often working during the day. Afterschool programs give working parents peace of mind; our most recent America After 3PM survey found that 74 percent of parents agreed afterschool programs help them keep their jobs. A safe, engaging place for kids to go after school turns out to be a pretty great gift for Dad.
Unfortunately, not all parents are able to enroll their child in an afterschool program. Ten million kids participate in an afterschool program now, but the parents of another 19 million would enroll their child if there were a program available. That means that for every child able to participate, two more are waiting to get into a program. Dads and moms value these programs for keeping their kids safe, inspiring them to learn, and giving them peace of mind when they are at work.
Tell Congress that every parent deserves the benefits that universal afterschool access can provide. When parents across the country are putting in 110%, elected representatives should be giving their all to increase funding for afterschool. It supports working parents like the #1 Dad in your life.
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text:
Gry 18+ - 3
Dla dorosłych
Blonde Rodeo
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Futa Courtney+Izzy
Enjoy this little animation about two shemales. These characters are taken from Canadian cartoon series Total Drama.Wyświetlenia: 63538
Jail Break 3
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Tsunade and Horse
Full Version of the game, where Tsunade gets laid with her own horse. Just imagine how much this animal can do :)Wyświetlenia: 156222
Breeding Season 6
Another update of Breeding Season game. Enjoy all latest places and features what author brings to us.Wyświetlenia: 179189
Sauna Fuck
Meet two hot girls in the sauna. Both of them want to fuck with you. Pick one of them and later fuck second one in all wholes, too.Wyświetlenia: 54666
Girls in Cubes
6 cubes are rotating. Your task is to stop each of them to combine one picture from all 6 pieces.Wyświetlenia: 22647
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Dream Job Season 2: Episode 3
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Hentai Math 5
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Summoners Quest Ch.7
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Sex Kitten: Insane Asylum
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Sexuality Level Test
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Ghost Fucker
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Kill la Kill
Enjoy this cool hentai animation where Matoi Ryuko from Kill La Kil gets fucked by horny tentacles in many ways. Click on the arrows located at the sides of the game to switch between scenes.Wyświetlenia: 129053
Another game where you can imagine your self as a P.I.M.P. Here you'll have a chance to build your own whore empire. Earn money and spend it on cool upgrades to earn even more cash. Buy new girls and send them to streets.Wyświetlenia: 151527
Fuck Town: Hypno Therapy
This time you can imagine yourself as a hypnotherapist. Today you have pretty blonde patient who has some kind of mental disorder. Anyway use your skills to strip her and see those lovely boobs and fuck that pussy.Wyświetlenia: 110131
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Night with Sara
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Are you Barbara Liori?Claim your profile
Publications (7)17.13 Total impact
- SourceAvailable from: Mario Giuffrè[Show abstract] [Hide abstract]
ABSTRACT: Abstract The objective of our study was to evaluate the capability of the metabolomics approach to identify the variations of urine metabolites over time related to the neonatal fungal septic condition. The study population included a clinical case of a preterm neonate with invasive fungal infection and 13 healthy preterm controls. This study showed a unique urine metabolic profile of the patient affected by fungal sepsis compared to urine of controls and it was also possible to evaluate the efficacy of therapy in improving patient health.Journal of Maternal-Fetal and Neonatal Medicine 10/2014; 27 Suppl 2:34-8. DOI:10.3109/14767058.2014.954787 · 1.21 Impact Factor
Article: Metabolomics Analysis and Modeling Suggest a Lysophosphocholines-PAF Receptor Interaction in Fibromyalgia[Show abstract] [Hide abstract]
ABSTRACT: Fibromyalgia Syndrome (FMS) is a chronic disease characterized by widespread pain, and difficult to diagnose and treat. We analyzed the plasma metabolic profile of patients with FMS by using a metabolomics approach combining Liquid Chromatography-Quadrupole-Time Of Flight/Mass Spectrometry (LC-Q-TOF/MS) with multivariate statistical analysis, aiming to discriminate patients and controls. LC-Q-TOF/MS analysis of plasma (FMS patients: n = 22 and controls: n = 21) identified many lipid compounds, mainly lysophosphocholines (lysoPCs), phosphocholines and ceramides. Multivariate statistical analysis was performed to identify the discriminating metabolites. A protein docking and molecular dynamic (MD) study was then performed, using the most discriminating lysoPCs, to validate the binding to Platelet Activating Factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine, PAF) Receptor (PAFr). Discriminating metabolites between FMS patients and controls were identified as 1-tetradecanoyl-sn-glycero-3-phosphocholine [PC(14∶0/0∶0)] and 1-hexadecanoyl-sn-glycero-3-phosphocholine [PC(16∶0/0∶0)]. MD and docking indicate that the ligands investigated have similar potentialities to activate the PAFr receptor. The application of a metabolomic approach discriminated FMS patients from controls, with an over-representation of PC(14∶0/0∶0) and PC(16∶0/0∶0) compounds in the metabolic profiles. These results and the modeling of metabolite-PAFr interaction, allowed us to hypothesize that lipids oxidative fragmentation might generate lysoPCs in abundance, that in turn will act as PAF-like bioactivators. Overall results suggest disease biomarkers and potential therapeutical targets for FMS.PLoS ONE 09/2014; 9(9):e107626. DOI:10.1371/journal.pone.0107626 · 3.53 Impact Factor
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ABSTRACT: Carbonyl groups are known to form covalent adducts with endogenous proteins, but so far, their nematicidal mechanism of action of has been overlooked. The nematicidal activity of ten lactones was tested in vitro against the root knot nematodes Meloidogyne incognita and Meloidogynearenaria. In particular, the saturated lactones α-methylene-γ-butyrolactone or tulipaline A (1) and γ-butyrolactone (3) were active against M. incognita with an EC50/48h of 19.3±10.0 and 40.0±16.2mg/L respectively. Moreover the α, β-unsaturated lactone 5,6-dihydro-2H-pyran-2-one (2) exhibited the strongest nematicidal activity against the two species with EC50/48h 14.5±5.3 and 21.2±9.7mg/L respectively. Here we propose that the toxic effects of lactones and aldehydes on M.incognita and M. arenaria might be a consequence of their vacuolar-type H(+)-ATPase (V-ATPase) inhibition activity; in fact α-methylene-γ-butyrolactone (1) and salicylaldehyde (12) produced an increased pH in lysosomal-like organelles on HeLa human cell line and this alteration was most likely related to a V-ATPase impairment.Pesticide Biochemistry and Physiology 06/2014; DOI:10.1016/j.pestbp.2014.05.002 · 2.01 Impact Factor
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ABSTRACT: Metabolomics, the latest "omics" technology aims to study the complete set of low molecular weight metabolites that may change according to the physiological or pathological state of the organism. Clinical studies dealing with metabolomics in neonatal and pediatric nephrology are very few. In this paper we present the experimental studies in newborn animal models, together with available data on human newborns. Finally the urine metabolomic profiling of 3 newborns who suffered from severe perinatal asphyxia and were treated with hypothermia. They are located in a different part of the multivariate space, the reason of the differences being the basal metabolic profile (resilience) of each neonate: 1 died and 2 survived (one of them developed an acute kidney injury). The main metabolites responsible of the different metabolic profile among the 3 newborns are presented. In the future each neonatologist and nephrologist should become skilled in the metabolomic field.Clinical Biochemistry 06/2014; 47(9). DOI:10.1016/j.clinbiochem.2014.05.020 · 2.23 Impact Factor
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ABSTRACT: The purpose of this article is to study one of the most significant causes of neonatal morbidity and mortality: neonatal sepsis. This pathology is due to a bacterial or fungal infection acquired during the perinatal period. Neonatal sepsis has been categorized into two groups: early onset if it occurs within 3-6 days and late onset after 4-7 days. Due to the not-specific clinical signs, along with the inaccuracy of available biomarkers, the diagnosis is still a major challenge. In this regard, the use of a combined approach based on both nuclear magnetic resonance ((1)H-NMR) and gas-chromatography-mass spectrometry (GC-MS) techniques, coupled with a multivariate statistical analysis, may help to uncover features of the disease that are still hidden. The objective of our study was to evaluate the capability of the metabolomics approach to identify a potential metabolic profile related to the neonatal septic condition. The study population included 25 neonates (15 males and 10 females): 9 (6 males and 3 females) patients had a diagnosis of sepsis and 16 were healthy controls (9 males and 7 females). This study showed a unique metabolic profile of the patients affected by sepsis compared to non-affected ones with a statistically significant difference between the two groups (p = 0.05).Early human development 03/2014; 90 Suppl 1:S78-83. DOI:10.1016/S0378-3782(14)70024-6 · 1.93 Impact Factor
Article: Potent Nematicidal Activity of Phthalaldehyde, Salicylaldehyde, and Cinnamic Aldehyde Against Meloidogyne incognita.[Show abstract] [Hide abstract]
ABSTRACT: The nematicidal activity of selected aromatic aldehydes was tested against the root knot nematode Meloidogyne incognita. The most active aldehyde was phthalaldehyde with an EC50 value of 10.59 ± 5.95 mg/L followed by salicylaldehyde and cinnamic aldehyde with an EC50 of 10.80 ± 0.99 and 12.12 ± 5.28 mg/L respectively. On the other hand, structurally related aldehydes such us 2-methoxybenzaldehyde, 3,4-dimethoxybenzaldehyde and vanillin were not active at the concentration of 1000 mg/L. By liquid chromatography mass spectrometry the reactivity of tested aldehydes against a synthetic peptide resembling the nematode cuticle was characterized. We report that at the test concentration of 1 mM, the main adduct formation was observed for 3,4-diihydroxybenzaldehyde, 2-methoxybenzaldehyde, 3,4-dimethoxybenzaldehyde Considering that 2-methoxybenzaldehyde and 3,4-dimethoxybenzaldehyde were not active against M. incognita in in vitro experiments lead us to hypothesize a different mechanism of action rather than an effect on the external cuticle modification of nematodes. When the toxicity of the V-ATPase inhibitor pyocyanin was tested against M. incognita J2 nematodes an EC50 at 24 h of 72.1 ± 25.3 mg/L was found. This toxicity was comparable with those redox-active compounds such us salicylaldehyde and phthalaldehyde suggesting a common mode of action inhibiting nematode V-ATPase enzyme. The results of this investigation reveal that aromatic redox-active aldehydes can be considered as potent nematicides, and further investigation is needed to completely clarify their mode of action.Journal of Agricultural and Food Chemistry 02/2013; 61(8). DOI:10.1021/jf305164m · 3.11 Impact Factor
Article: Nematicidal Activity of 2-Thiophenecarboxaldehyde and Methylisothiocyanate from Caper (Capparis spinosa) against Meloidogyne incognita[Show abstract] [Hide abstract]
ABSTRACT: New pesticides based on plant extracts have recently gained interest in the development of nontoxic crop protection chemicals. Numerous research studies are focused on the isolation and identification of new active compounds derived from plants. In this manuscript we report about the use of the Mediterranean species Capparis spinosa as a potent natural nematicidal agent against the root knot nematodes Meloidogyne incognita. Leaves, stems, and caper buds of Capparis spinosa were used to obtain their methanol extracts (LME, SME, BME) that were successively in vitro tested against second stage nematode juveniles (J2). In terms of paralysis induction, the methanol extract of the stem part (SME) was found more effective against M. incognita and then the caper methanol buds and leaves extracts. The chemical composition analysis of the extracts carried out by GC/MS and LC/MS techniques showed that methylisothiocyanate was the main compound of SME. The EC(50) for SME after 3 days of immersion was 215 ± 36 mg/L. The constituent components of SME such as 2-thiophenecarboxaldehyde and methylisothiocyanate were successively in vitro tested for their nematicidal activity against J2. Both compounds induced paralysis on root knot nematodes ranking first (EC(50) = 7.9 ± 1.6, and 14.1 ± 1.9 mg/L respectively) for M. incognita. Moreover, 2-thiophenecarboxaldehyde showed a strong fumigant activity.Journal of Agricultural and Food Chemistry 07/2012; 60(30). DOI:10.1021/jf302075w · 3.11 Impact Factor
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Università degli studi di Cagliari
Cagliari, Sardinia, Italy
- Department of Life and Environmental Sciences