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Green Bay Packers Rout Minnesota Vikings, 42-10
Eddie Lacy ran for 105 yards and two touchdowns, and the Green Bay Packers embarrassed the Minnesota Vikings, 42-10, at rainy Lambeau Field in Wisconsin on Thursday night.
Eddie Lacy ran for 105 yards and two touchdowns, and the Green Bay Packers embarrassed the Minnesota Vikings, 42-10, at rainy Lambeau Field in Wisconsin on Thursday night.
Jamaal Charles scored three touchdowns, and the Chiefs thoroughly dominated the New England Patriots, 41-14, in Kansas City on Monday night.
A previously unbeaten team lost, and a formerly winless team tasted victory for the first time this season during the thrilling NFL action on Sunday. Here are the most interesting things we learned in Week 4:
Eli Manning threw four touchdown passes and ran in another score, and the New York Giants routed the Washington Redskins, 45-14, in Landover, Md. on Thursday night.
The 2014 NFL season is nearing the end of its first quarter. Week 4 brings the first byes of the year, a fiery old friend facing his former team for the first time and several key games. Here's what to look forward to this week:
After the most exciting week of the season so far, we have a handful of big games and key conference matchups this week. Here are some of the big questions this week.
Jay Cutler threw two touchdown passes to Martellus Bennett, and the Chicago Bears held on to beat the New York Jets, 27-19, on Monday night in northern New Jersey.
Dramatic victories and amazing comebacks highlighted Week 3 of the 2014 NFL season. Here's a recap of all of this weekend's action:
Rob Bironas, husband of country newcomer Rachel Bradshaw, died in a single-vehicle accident Saturday night (Sept. 20) in Nashville.
NFL Commissioner Roger Goodell held a press conference to address the recent string of violent incidents involving players assaulting women and children.


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U.S. Embassy In Kabul Hit By Indirect Fire
Originally published on Thu December 26, 2013 2:10 am
The U.S. Embassy in Kabul, Afghanistan, was hit by indirect rocket fire Wednesday morning, officials say. NPR's Sean Carberry reports for our Newscast unit that no one was injured.
"They hit in an open area; they didn't strike any of the embassy buildings. There was no damage to embassy facilities, and there were no causalities," he said.
Embassy officials say they are investigating. Taliban insurgents claimed they fired rockets at the embassy, but they often make claims that turn out to be exaggerated or untrue.
At least six people were killed in attacks elsewhere in Afghanistan on Wednesday, The Associated Press reports. An Afghan official told the news agency a bomb on a bicycle was detonated in front of a restaurant in Logar province. Two of those killed were police officers and four were civilians, AP reports.

subset: commoncrawl


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Keep up with Tigers news during winter meetings
DEC 02, 2012 6:43p ET
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The corporation of Shrewsbury: Bailiffs' accounts
The Manuscripts of Shrewsbury and Coventry Corporations [Etc] Fourth Report, Appendix: Part X
The corporation of Shrewsbury Bailiffs' accounts V.Bailiffs ... of bailiffs. In those others, together with one more, are found the following ... to London. The roll for 1310 11...
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Appendix: Lists of provosts, bailiffs and other officers
Extracts From the Records of the Burgh of Edinburgh, 1403-1528
Appendix Lists of provosts, bailiffs and other officers Lists of provosts, bailiffs and other officers [The election of magistrates ... Schele, Deam of Guild and Keeper of the Kirk work,Custoditer...
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Possessions of the priory: Outside London
The Records of St. Bartholomew's Priory and St. Bartholomew the Great, West Smithfield: Volume 1
Possessions of the priory Outside London Outside London The main ... of the possessions. By the Rental we find that the monastery possessed in London ... and rents and tenements in 53 ...
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The French Chronicle of London: Edward III
Chronicles of the Mayors and Sheriffs of London 1188-1274
The French Chronicle of London Edward III Edward III Edward ... to the citizens of London all their franchises which they had before lost, and also ... against the Scots, and had from London 200...
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Sources: London religious houses and bishopric
A Survey of Documentary Sources For Property Holding in London Before the Great Fire London Record Society, 22
Sources London religious houses and bishopric RELIGIOUS HOUSES ... or advowsons, in the city of London. The houses can be identified, ... of London in 1392, in A. K. McHardy, The Church in...
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Appendix: Mayors and sheriffs of London, 1199-1470
The Historical Collections of A Citizen of London in the Fifteenth Century
Appendix Mayors and sheriffs of London, 1199-1470 APPENDIX. MAYORS ... which is printed in Report XXXI. of the Deputy Keeper of the Public Records, page ... of Richard I. Fabyan inaccurately places the sheriffs (...
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London and Middlesex Fines: 1-12 Elizabeth
A Calendar To the Feet of Fines For London and Middlesex: Volume 2, Henry VII - 12 Elizabeth
London and Middlesex Fines 1-12 Elizabeth ELIZABETH. John Fytz, ... near Westsmythfeld, London. L. Hil. Anno 1. William, earl of Worcester, ... of Christ Church, London. L. Hil. Anno 1. Hugh...
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Close Rolls, Henry IV: June 1400
Calendar of Close Rolls, Henry IV: Volume 1, 1399-1402
Westminster. To the sheriffs of London and the keepers of the passage ... of Portesmuth and the keepers of the passage in that port. The bailiffs of Rye ... Westminster. To the...
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Close Rolls, Henry IV: March 1404
Calendar of Close Rolls, Henry IV: Volume 2, 1402-1405
of Exeter and the keepers of the passage. The mayor, bailiffs etc. of Suthampton and the keepers etc. The mayor, bailiffs etc. of Cicestre and the keepers etc. The...
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Close Rolls, Richard II: September 1377
Calendar of Close Rolls, Richard II: Volume 1, 1377-1381
Westminster. To the mayor and sheriffs of London, and the keepers of the passage ... to the following: The mayor and bailiffs of Gippewich and the keepers of the passage ......
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text: We had to stay here as other places in the area was sold out. The staff is very nice and they are accommodating. The rooms are dated and have an odor, not sure what the smell is but it's there. No elevators if you have a room on the second floor. They have an okay breakfast which is included in... More


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13005 - Dachgeschoss
from £39 /night help Price for guests, Nights
from £39 /night help Price for guests, Nights
Estimated nightly price based on a weekly stay. Excludes fees (if applicable). Enter your dates to see the total cost.
Apartment / 2 bedrooms / sleeps 4
Availability Your dates are available
Apartment / 2 bedrooms / sleeps 4
|Key Info
3-room apartment 50 m2, on the top floor, with sloping ceilings: small living/dining room with satellite-TV, radio and CD-player. 1 room with 2 beds. 1 double bedroom. Kitchenette (oven, electric coffee machine). Bath/shower/WC. Please note: non-smokers only. Private entrance.
Cosy 2-family house. On the outskirts, 900 m from the centre of Westerholt, in a quiet position in the residential district, 11 km from the sea, 11 km from the beach. For shared use: well-kept garden (fenced). Private: patio, garden furniture, barbecue. In the house: store for bicycles, central heating. Available: bicycles (2), children's bicycles (2). Parking by the house. Shop 900 m, supermarket 500 m, restaurant 300 m, bus stop 100 m, railway station 'Aurich' 15 km, sandy beach 11 km, indoor swimming pool 11 km. Tennis 12 km. Please note: car essential. Garden house with seating corner and bar for shared use.
|Sleeps up to 4, 2 bedrooms
|Family friendly
|Great for children of all ages
|No pets allowed, No smoking at this property
Features and Facilities
|2 bedrooms, 1 bathrooms of which 1 Family bathrooms
|4 Sofa beds
|Suitable for people with restricted mobility, Not suitable for wheelchair users
The Lower Saxony region
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Calendar last updated:30 Jun 2015
Based in United States
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1990 Dodge Ram 50 Q&A
1990 Dodge Ram 50 Question: Overdrive not engaging.
1990 Dodge Ram50 4WD with 2.4L 4 speed automatic transmission and the overdrive won't stay engaged. Swapped out the tranny solenoid and fresh fluid and filter, i thought the solenoid screens were clogged. It will shift into OD and stay for just a minute and then right back to drive and stay there. Any suggestions would be great. Thank You in advance, Jim - csms_ford
Answer 1
The PCM controls the overdrive solenoid. It is possible you may have a poor connection either at the PCM or the overdrive solenoid connectors. make sure all are clean and secure. Also, FYI, if your brake switch is defective, it will kick off the overdrive as well. - Johnny Mopar
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Videos tagged "Kirkwood"
70 Plays / 1 Likes / 0 Comments
627. It is our "magic" number, the number that is always a current in our lives. This is Keith's second project ever. Shot with a Canon Markii. Scenes include downtown Atlanta, scenes from the Atlanta Arts Festival, and the neighborhoods of Kirkwood, Cabbagetown, and random stuff around our home.+ More details
18 Plays / 0 Likes / 0 Comments
Legs gave out, did a 360 and luckily no pain.+ More details
789 Plays / 2 Likes / 0 Comments
Fun day at the wood!!!+ More details
11 Plays / 0 Likes / 0 Comments
A compilation video of Aaron Meyers skiing at Kirkwood in the winter of 2009-2010+ More details
99 Plays / 0 Likes / 0 Comments
Find out about Kirkwood, the Hospice for Kirklees+ More details
33 Plays / 0 Likes / 0 Comments
A short little video from a few days of riding this year in South Lake Tahoe, California. Starring Nate Calhoun and Travis Green. Shot by Nate Calhoun and Travis Green. Time lapse by Nate Calhoun+ More details
198 Plays / 0 Likes / 0 Comments
Just a little one day edit could of gotten more but decided to throw this together. Song: Give Me The Beat Artist: Ghostland Observatory+ More details
1,016 Plays / 3 Likes / 0 Comments
10/3/2014 at Kirkwood Mountain Resort, CA+ More details
After mis amigos! 3" to 5" of Mother Nature Natural @ The Wood!04:11
136 Plays / 0 Likes / 0 Comments
Hola my friends, Monday morning with fresh snow is the way to start the week here @ The Wood! A few more systems in the mix & headed our way, so get your POW Hunt'n tags out because winter is still here in the HAUS of the (209)! Big props and thanks to all of those that helped us present the Sierra Nevada Celebration days here, Sierra Nevada, Marmot, Burton, Volcom, 4FRNT, Scott & all of the volunteers & staff! Lake Valley Fire, CHP & Alpine County Sheriffs department all had a hand in making the event go smooth... This week we host the Northface masters of the Mountain big mountain snowboard comp! Registration is on the 28th comp over the weekend... Mother Nature keeps us in the fresh all week, book your lodging now for the weekend of fresh snow & big mountain madness all here this weekend! Stay'n Thirsty for POW! Coop+ More details
17 Plays / 0 Likes / 0 Comments
some stupid stuff that somehow got filmed and its not much but its new. its at kirkwood+ More details
What are Tags?
Tags are keywords that describe videos. For example, a video of your Hawaiian vacation might be tagged with "Hawaii," "beach," "surfing," and "sunburn."


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On my Blog page at http://www.xava.ie/blog/ - I want to change the post meta. Specifically, it says 0Comments and 0 reactions - I want to change that to just 0 Comments.
So I copied the pagelines_post_comments_shortcode function into the child theme functions.php and edited the code to just pring out the number of comments and leave out the reactions.
Actually I am not certain that I have got it right because I dont know how to override the default pagelines fuction and use my own one from the child theme functions.php?
Or is there an easier way of achieving what I want to achieve?
Thanks in advance


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Apr. 28 - Help support early detection of abdominal aortic aneurysm (AAA) at a free AAA ultrasound screening and AAA speaker event. AAA is a ballooning of the abdominal aorta, the artery that carries blood to the lower part of the body.
Maureen MackDirector of External Communications(414) 955-4744 (Office)(414) 750-5266 (Cell)firstname.lastname@example.com
Richard N. KatschkeAssociate Vice President(414) firstname.lastname@example.com
Medical College of Wisconsin
8701 Watertown Plank Road
Milwaukee, WI 53226
(414) 955-8296
Directions & Maps
© 2015


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Category:Lao terms with obsolete senses
Definition from Wiktionary, the free dictionary
» Lao language » Terms by usage » Terms with obsolete senses
Lao terms that are no longer in current use, but found in older texts.[edit]
- Category:Lao obsolete forms: Lao terms that are found in older texts and are no longer in current use, because they changed in comparison with recent general use.
This category has only the following subcategory.
- ► Lao obsolete forms (0 c, 18 e)


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Mentoring Teen Girls
6 of 6
Get to Know Her
You don't have to have a daily heart-to-heart with your daughter to get insight into her issues and problems, Dawn says. Instead, connect with her on something simple she's interested in, such as music or makeup. Let your daughter pick a weekly activity or class focused on her interests that you both can take together. Spend that time—at least two hours a week—focusing on your daughter and the task at hand. "She most likely won't acknowledge it, but it feeds her soul to know she was your universe for those two hours," Dawn says.
How to help girls with their body image
How to help girls with their body image
The information provided here is for entertainment and informational purposes. You should consult your own physician before starting any treatment, diet or exercise program. The opinions expressed by the hosts, guests and callers to Oprah Radio are strictly their own.


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Philosophy Open House
Interested in Philosophy? Please come to an Open House for Prospective Philosophy Majors on:
Thursday, February 23, 2012
8:00 - 9:00 p.m.
716 Philosophy Hall
Meet faculty, current majors, and other prospective majors, and ask all your questions!
Pizza will be served.
For more information, please contact Maia Bernstein, firstname.lastname@example.com.
Philosophy Open House (2/23)
Philosophy Open House


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6:41 pm
Wed August 8, 2012
Cue The Tape: How David Barton Sees The World
By Elise Hu
David Barton is not a historian. But his version of American history is wildly popular with churches, schools and the GOP. With help from historians Warren Throckmorton and Michael Coulter, co-authors of Getting Jefferson Right, we fact-checked a few of Barton's more common claims. Watch video examples of Barton's messages and see how they compare with the Constitution, historical text and the Bible.
Copyright 2013 NPR. To see more, visit http://www.npr.org/.


text: Hotel Elegant International Quick Specs Rates $19-$29Year Built 1995Year Renovated 2014 View Large Interactive Map Address 6/28, W.E.A., Ajmal Khan Rd Karol BaghDelhi, India 110005 Web http://www.hotelelegantdelhi.in/ Phone + 91 11-2875-9130 Fax + 91 11-4145-1916 Toll-free Email email@example.com OverviewMeeting SpecsPhotos & videos Description Year Built: 1995Year Renovated: 2014Check in Time: 12:00 PMCheck out Time: 12:00 PMNumber of Floors: 4Total Number of Rooms: 24Rates: $19-$29 Hotel Elegant International Location & NeighborhoodIn Delhi. Hotel Elegant International Rates & PoliciesHotel Elegant International rates are Daily in USDStandard: $19-$29 Credit Cards Are AcceptedReservations must be guaranteed with a credit cardMeals: No Meals Included Nearby AirportsIndira Gandhi Intl (9.25 miles southwest)Kheria (113.25 miles southeast)Jolly Grant (121.50 miles northeast)More Airports » Hotel Elegant International Room AmentitiesHotel Elegant International amenities are in All rooms unless noted otherwiseAir ConditioningCoffeemaker (some)Rooms for Non-smokersTelephoneRefrigeratorCable/Satellite TelevisionInternet Access (High Speed & Wireless) Guest ServicesLaundry/Dry Cleaning ServiceMulti-lingual StaffPaid Onsite ParkingRoom ServiceCommon Area Internet Access (High Speed & Wireless) Nearby SightseeingRed Fort (2 miles east)Jantar Mantar (2 miles southeast)Majnu ka Tilla Tibetan Colony (2.25 miles northeast)Buddha Jayanti Park (2.25 miles northeast)National Gallery of Modern Art (2.25 miles northeast)More sightseeing »DiningFrontier (2 miles northeast)Coffee Home (2 miles southeast)United Coffee House (2.25 miles southeast)Tamura (2.25 miles northeast)Diva (2.50 miles east)More dining options » Nearby RecreationGolf CourseHealth ClubHealth Spa/MassagePool (Indoor Pool, Outdoor Pool) Hotel Elegant International Meeting Rooms & Events Hotel Elegant International Images, Videos, & Virtual Tours Photos & Videos Hotel Elegant International Room Nearby Delhi Hotels More Nearby Hotels Broadway HotelHotel VikramThe ConnaughtBest Western Resort Country ClubCountry Inn by Carlson Delhi SaketAshok HotelClarion Collection Qutab Hotel & AptsDiplomat HotelHans Plaza HotelJaypee Vasant Continental HotelMaidens HotelRadisson Hotel DelhiThe Claridges, New DelhiThe Grand New DelhiThe Lalit New DelhiThe Park New DelhiThe Suryaa New DelhiVivanta by Taj - AmbassadorJaypee Siddharth Hoteliers! Is your listing up to date? With over 130,000 hotels in our database, no other source compares to our depth of information. Click here to review and be sure the travel professional knows your hotel's latest details.


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By: Johanz
The intro from Suikoden III! Enjoy! :)
Views: 1,409 | Posted: 02/06/2009
By: Terpor
Suikoden 3 INTRO PS2 - RPG One of the best PS2 RPG
Views: 1,523 | Posted: 10/21/2008
By: Rtx admin
Im editing quite a few movies right now and im long over due with uploading a new/old FM I made it 3 years ago so don't expect it to be Epic like my new FM's. I can't even remember when i used that intro but i know it's old.
Views: 1,438 | Posted: 08/23/2006
Views: 11,275 | Posted: 12/01/2004
Week of
Jul. 05
Week of
Jul. 12
Release Date: 07/08/2015
Team17 brings a classic Worms battle back to PC with Steam integration.
PC, Android, Windows Phone 8, iOS
Release Date: 07/12/2015
Combine the skills of multiple characters to solve puzzles and the mystery.
Release Date: 07/14/2015
Kratos' epic on PS3 is coming to PlayStation 4 in full HD and with new features.


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Allergy Guard Pristine Bedding
GHRI scientists found that this bedding became softer after each wash, with just a little shrinkage and no change in appearance. While the bedding fit on the mattress with ease, our testers said they had to strong-arm their pillows into the protectors. allergyguarddirect.com
Fabric: 100% microfiber polyester.
Reviewed: September 2010
Price When Reviewed: $66.00 –$130 for Encasement; $15-$19 for Pillow Protect
- Easy to put on and take off the mattress
- There was little shrinkage and no change in the product after multiple washes and dries
- The fabric got softer with each wash
- Cut a bit small for the average pillow; it took some maneuvering to close the zipper
- This fabric is not very breathable
- Neither waterproof nor water-resistant
What do you think?
Craftsman C3 1/2-Inch Heavy-Duty Drill
This 19.2-volt beast will help you tackle tough projects quickly and effectively.
BLACK+DECKER MATRIX 20V MAX Lithium Drill/Driver
Compatible with many extra attachments, this drill is a smart pick for those who want more diversity in their toolkits.
BLACK+DECKER 20V MAX Lithium Drill/Driver with AutoSense Technology
This drill's AutoSense Technology will recognize when a screw is in place, and then engage by itself — eliminating any speculation or...
RYOBI 18V One+ Lithium-Ion Drill/Driver Kit
The RYOBI 18-volt lithium-ion kit is a good addition to any toolbox.
More From Home & Garden Products


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Beauty on a Back Street
From Wikipedia, the free encyclopedia
|Beauty on a Back Street
|Studio album by Hall & Oates
|September 1977
|Pop, rock
|Christopher Bond
|Hall & Oates chronology
Beauty on a Back Street is the sixth studio album by Hall & Oates, released in 1977.
This album takes a more rock-oriented approach, similar to War Babies, but more streamlined and polished.
Both Daryl Hall and John Oates claim to hate this album, and many of Hall and Oates' most comprehensive compilations, such as The Essential Daryl Hall & John Oates (originally released as Ultimate Daryl Hall + John Oates) and the 2009 box set, Do What You Want, Be What You Are: The Music of Hall and Oates, do not include any songs from this album (although the "3.0" edition of The Essential does contain the album's sole charting single, "Why Do Lovers Break Each Other's Hearts?" as a bonus track).
|Professional ratings
|Review scores
|Rolling Stone
|(not rated) link
Track listing[edit]
- Side One
- "Don't Change" (Hall, Oates) (3:37)
- "Why Do Lovers Break Each Other's Heart?" (Sara Allen, Hall) (3:16)
- "You Must Be Good for Something" (Hall, Oates) (3:32)
- "The Emptyness" (Oates) (3:35)
- "Love Hurts (Love Heals)" (Oates) (3:11)
- Side Two
- "Bigger Than Both of Us" (Hall, Oates) (4:31)
- "Bad Habits and Infections" (Hall) (6:03)
- "Winged Bull" (Hall) (4:39)
- "The Girl Who Used to Be" (Oates) (4:10)
- Daryl Hall - vocals, synthesizer, guitar, vibraphone
- John Oates - vocals, dulcimer, synthesizer, guitar, piano
- Tom Scott - tenor saxophone
- Christopher Bond - synthesizer, guitar, arranger, conductor, string arrangements
- Gary Coleman - percussion
- Scott Edwards - bass
- Jim Hughart - bass
- Tommy Mottola - background vocals, direction
- Jeff Porcaro - drums
- Lee Sklar - bass
- Produced by Christopher Bond
- Recorded and Engineered by John Mills and Armin Steiner (engineered strings)
- Assistant Engineer: Linda Tyler
- Mastered by Pat Martin
|This 1970s pop album-related article is a stub. You can help Wikipedia by expanding it.


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Animethon 22
- Film, Media & Entertainment
- 10700 104 Ave NW, Edmonton, AB, T5J 4S2
Mix 'N Mingle w/ Chef Parker
Steve & Kim's Mixer
Friday, March 1, 2013 from 6:00 PM to 9:00 PM (MST)
Come join us for an evening of relaxation, friends, great food and drinks with one of the best personal chefs in Edmonton!
This great mixer will be held at the fantastic event center at;
711 50 St. (This is on Ellerslie Rd just east of 50 St) Nor'Westers Rugby Club
Friday March 1, 2013
($10.00 per person cash at the door)
We will have Appetizers, platters, there will be gluten free & vegetarian options available plus MORE!
Chef Parker will be having a food trivia station as well as make your own sushi station!
Sit back around the fireplace and enjoy this mixer with other local business owners and Twitter friends. A casual event designed to mingle and/or network with some fantastic people.
We expect this event to sell out so please register now.
Follow the organizers:
Join millions of people on Eventbrite.
In order to purchase these tickets in installments, you'll need an Eventbrite account. Log in or sign up for a free account to continue.


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Stock Photo:
Young woman practicing yoga in the lotus position
- Image ID: 76696891
- Copyright: Inga Ivanova
- Release Information: Signed model release filed with Shutterstock, Inc
High quality images curated from over 150 countries.
Over 50 million photos, vectors, illustrations, and more.
Simple and flat pricing by image or by month.
Over 230,000 images downloaded every day.


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One thing Jeb Bush might not have to worry about during a presidential campaign: Newsy comments from his outspoken mother.
Philadelphia police are searching for two men after a woman was shot in the face after answering her front door in Hunting Park.
Gov. Andrew Cuomo announced Sunday that a $100,000 reward is being offered for the capture of two convicted murderers who escaped from a maximum-security prison in upstate New York, apparently through a hole in the back of their cell.


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Original recipe yields 16 servings
Amount per serving ({{servings}} total)
Based on a 2,000 calorie diet
Ready In
I made a double batch for a baby shower, and everyone loved it! I wanted to take a picture, but it disappeared way too quickly! I thought it was very good and very easy. The pink was a darker sh...
Made this for our Christmas Eve dinner. It was a big hit. I frozen some of the punch and added it to the bowl to keep it chilled. (Jello mold or an ice tray would work.)


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Joomla gallery extension by joomlashine.com
Villa Hills Slideshow
Welcome to Villa Hills
According to the 2010 census we have 7,489 residents and about 2,800 homes. Whether you are a long time resident, planning to buy a home here, or just making a visit, you will be a part of the number 1 suburb in Greater Cincinnati designated by Cincy Magazine. Villa Hills was also named the 7th best suburb in the USA.
We have two excellent schools, River Ridge Elementary and Villa Madonna Academy grade school and high school. In addition we have Villa Madonna Montessori. We are proud to have the Sisters of St. Walburg Monastery and the Madonna Manor Complex which is home to a sizable retirement community.
The City operates under the Mayor/Council form of government and is a Home Rule class city under Kentucky Law.
Please do not hesitate to call us at the City Building at 859.341.1515 for any assistance.
Thank you,
Mayor Butch Callery
Part-time Police Officer Search
Public Feedback Requested:
The intersection at Niewahner, Buttermilk, and Valley Trails will be reconstructed in the summer of 2015. The current proposal calls for the Niewahner traffic island to be relocated to the west side of the street to improve access to the greenspace and improve traffic flow at the intersection. Please review the drawing linked here and then share your comments with the Mayor and Council.
A note to residents about the Utility Service Partners warranty letter
Residents of Villa Hills will receive a letter from Utility Service Partners, signed by the Mayor, offering warranties for sewer and water line laterals. This is NOT a scam. Villa Hills has partnered with Utility Service Partners through the National League of Cities to have this program offered in our community. It is strictly voluntary. Residents are encouraged to contact their insurance agent to see if coverage already exists for your sewer and waterline laterals. Homeowners are responsible for the repair and maintenance of their laterals to the main. Residents who participate in an Home Owners Association (HOA) should check with their board to see if this issue falls to the HOA. The City of Villa Hills is not receiving any payment or commission for the issuance of any warranties. Several other communities in Northern Kentucky also offer this program.
Many residents have called asking if this letter is legitimate. It is. We thank our residents for their vigilance and for watching out for our community.
Mayor Callery's Budget Message to Council
Mayor Butch Callery presented his budget message at the April 15th Council meeting. The annual budget message is required by KRS 91A.030(7).
Villa Hills ranked 7th Best Suburb in the USA
Villa Hills also ranked #1 Best Burb in Greater Cincinnati by Cincy Magazine
Lane and Road Closure Notice: UPDATE 6/25/15
Road work restart delayed due to bad weather.
Many residents have called into the city building over the past few days with questions about the continued closure of Buttermilk between Rogers and Niewahner. New concrete needs 7 to 10 days to cure before vehicles can use the new roadway. Work was stopped by the contractor to allow for this curing period. During the curing period several days of rain have delayed the project's restart and more rain is expected. Villa Hills, our engineer, and the contractor are aware of the inconvenience caused by this weather related delay. Every effort is being made to complete the project as soon as weather allows.
During the closure, traffic will be detoured to Amsterdam via Niewahner. Plan your route accordingly and allow more time to reach your destination.
Please be advised that a follow-up project to replace the intersection of Valley Trails, Buttermilk, and Niewahner will commence shortly after this project ends extending the road work in this area by several additional weeks.
Thank you for your continued patience.
The spring edition of the city newsletter is now available!
Reds Kid Glove Tickets 2015
Reds fans can save money and support instructional baseball in Villa Hills / Crescent Springs! Tickets are only $12.00 each ($18.00 value) and $10.00 of each ticket sold gets returned to Villa Hills Instructional Baseball to buy equipment! See the order form for eligible games and payment information.


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Zotac GeForce GTX 980 Ti AMP! Extreme Review
PowerColor Radeon R9 390 PCS+ 8GB review
MSI GeForce GTX 980 Ti Gaming OC Review
Guru3D Rig of the Month - June 2015
AMD Radeon R9 Fury X review
Corsair RM750i power supply review
MSI Radeon R9 390X Gaming 8G OC review
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Forceware 60.80 Windows 2000|XP
Posted by: Hilbert Hagedoorn on: 05/02/2004 12:02 PM [ 0 comment(s) ]
Windows 2000/XP
Private Bryer from our forums stumbled into 60.80 Forceware's while browsing the web.
The original .inf file has been altered by our forum buddy SL2 to support all graphics cards. I in fact tested the setup in collaboration with a GeForce 6800 Ultra and they work just fine.
Give them a try if you want to that is ! The drivers have been virus checked. The drivers are dated April 8th 2004. If you use these drivers then remember, consider them beta thus you use them at your own risk ! If you give the drivers a try then be sure to let us know your experiences in our NVIDIA driver forums.
« RightMark Memory Analyzer 3.1 · Forceware 60.80 Windows 2000|XP · ForceWare 61.11 Windows 2000|XP »


text: Miley Cyrus Speaks on Hospitalization by Free Britney at April 29, 2014 3:53 pm. Comments Share Tweet Email Miley Cyrus speaks out for the first time since her hospital stay, telling Ryan Seacrest about the allergic reaction that led to her extended stay. Edit Delete Follow Miley Cyrus? Star: Miley Cyrus Related Videos: Miley Cyrus Videos Related Post: Miley Cyrus Speaks on Hospitalization: I Was Poisoning Myself Uploaded by: Free Britney Uploaded: April 29, 2014 Duration: 96 seconds


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Australia and New Zealand Report
By Editorial Staff
Published December 22, 2007
ADELAIDE, Australia (FR) – Three thousand Christians marched down the main streets of this Australian city early this year, proclaiming God's ownership of the city and praying for the government as the parade halted in front of various city offices and business houses. The rally, held in conjunction with a nationwide Christian conference called Revival '89, was yet another visible sign of the impact Christianity is having upon the nation of Australia.
Participants in the parade were numerous young people from Maranatha fellowships in New Zealand and Australia, some of whom had only been recently converted to Christ. Bob Weiner, founder and president of Maranatha Campus Ministries, was a keynote speaker at the convention – which drew leaders from throughout the Pacific region.
The Adelaide conference, sponsored by Barry Chant, leader of Tabor House, underscored a year of Christian activity that caused even secular observers to marvel. Last September, a constitutional amendment which many Christians feared would curtail civil and religious liberties was resoundingly defeated. One noted newspaper columnist in a Melbourne daily wrote of that event: "Christians have made their presence felt during the last year more than at any other time in our history. Voters turned down the national referendum that would have given government a stronger voice … I suspect (the Christians') opposition did much to influence voters. As for this writer, I welcome the Christian viewpoint in Australia. It's about time we heard from them."
There was also more movement toward Christian unity in Australia last year as over 35,000 people, including youth from Maranatha churches in Melbourne and Sydney, joined the National Prayer Gathering in the nation's capitol, Canberra. In keeping with the 200th birthday celebration of Australia, the Bible Society last year organized Christians to distribute Bibles to every household in the country.
Meanwhile, Maranatha campus churches in Sydney and Melbourne continued to grow last year, adding more international students from southeast Asia than ever. More than 24,000 Australian editions of Forerunner were printed and distributed on campus. According to Grant Clark, editor of the newspaper, the publication of an Australian edition dovetailed with the nation's bicentennial, which "allowed the nation to focus on its foundations and achievements. It has also allowed a time to ponder our future. Many politicians, church leaders and sportsmen have called for Australia's youth to lay the foundation for the next 200 years."
Evangelism has penetrated the Sydney University campus so powerfully that a recent poll disclosed that Christians have become the second largest group on campus, second only to the ski club! Christians are also making inroads into politics. In New South Wales, three Christians formed "Call to Australia," a new political party. During a hotly contested election, three party members were swept into office and now control the balance of power in the New South Wales Upper House. In Adelaide, the Student Representative Council President is a Christian and a member of an Assembly of God Church.
With this growth of Christian influence has also come an increase in Australia's stature worldwide. NBC Television spent a week televising live segments of the Bicentennial celebration, giving millions of Americans a window into a country they have known little about. Recent movies about life in Australia, such as "Crocodile Dundee I and II" and "A Cry in the Dark," have sparked a new wave of tourism – making it the number one industry in Australia. Hotels and related industries are building beachheads in not only the capitol cities of Sydney and Melbourne but also in medium-sized cities and resort towns where experts are predicting over 5 million tourists a year will visit by the turn of the century.
Visitors to Australia say there is a new spirit in the land, an enthusiasm and excitement that is translating into positive economic effects for the nation. Even though socialism has lurked in the culture for decades, a renewed free enterprise fervor is gripping the land, making Australia more prosperous than at any time in its history. "Aussies feel good about themselves," says Pastor Mark McClimens, who credits much of the change to the spiritual revival that is sweeping the land.
Meanwhile, in New Zealand, the promise of spiritual renewal is touching a country that one internationally-known Christian leader says "could go Marxist at any time unless a mighty Christian revival washes the land clean." Maranatha Campus Ministries has accepted the challenge to help change the nation: a team of 10 Americans, led by pastor Bob Muni, is now surrounded by a band of young, enthusiastic new believers who are preaching on campus and sharing Jesus Christ in classrooms, cafeterias and in their homes.
Christians who came to the campus during the Auckland outreach were amazed by the openness of unbelievers who wanted to hear the gospel. Pastor Muni says he wants to bring New Zealand back to its spiritual moorings, and believes his core group of 45 are making an impact on the nation even though the campus fellowship has been active for less than a year.
The young people in the Auckland church have a passion to impact the world. Angela McGrath, 21, a freshman from England studying at the University of Auckland, says she wants to "restore the education system in New Zealand to godly principles." Presently, Angela says feminists and lesbians are running the teacher's college where she is enrolled. "We are raising up a new generation of Christian leaders in every area of life," she added.
Nineteen-year-old engineering student David Senn watched Muni and evangelist Ken Dew preach boldly in the student union quad area during last summer's outreach He gave his life to Christ as a result, and now stands in the same spot to preach his own messages. Senn commented: "I want to see us in student government next year to raise God's standard on the campus."
Larry Goodall, 21, a recent mechanical engineering graduate, is working for the government "to be a shining light." Goodall and dozens of other students say the campus was impacted by Maranatha's summer outreach. "When the Maranatha team arrived, it shook the campus," reported Megan Hughes, an 18-year old freshman majoring in science. "I was one of the people who was totally adamant that I would not get 'saved'! But I realized there was more to life than partying and drinking. I realized I had not gone to that meeting by chance. God had drawn me!" Megan says she wants to travel and witness to people all over the world about Jesus Christ. Right now, however, she admits there is much missionary work to be done at Auckland University.
But things are just beginning in New Zealand. Ken Dew and a team of young Maranatha evangelists will hit the Auckland campus once again in July of this year. If you are interested in being part of this venture, plus a 20-day evangelism thrust in Sydney and Melbourne, Australia, write: Maranatha Missions, P.O. Box 1799, Gainesville, FL 32602.
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Dr. Francis Schaeffer - A Christian Manifesto (DVD)
That Swiss Hermit Strikes Again!
Dr. Schaeffer, who was one of the most influential Christian thinkers in the twentieth century, shows that secular humanism has displaced the Judeo-Christian consensus that once defined our nation's moral boundaries. Law, education, and medicine have all been reshaped for the worse as a consequence. America's dominant worldview changed, Schaeffer charges, when Christians weren't looking.
Schaeffer lists two reasons for evangelical indifference: a false concept of spirituality and fear. He calls on believers to stand against the tyranny and moral chaos that come when humanism reigns-and warns that believers may, at some point, be forced to make the hard choice between obeying God or Caesar. A Christian Manifesto is a thought-provoking and bracing Christian analysis of American culture and the obligation Christians have to engage the culture with the claims of Christ.
$19.95 — ORDER NOW!(We accept all major credit cards and PayPal.)
Click here for more information
Massacre of Innocence (DVD)
Exposing The Occult Roots of Abortion
This presentation looks at the spiritual roots of abortion and exposes the myths surrounding child killing. Little known historical facts about abortion and how they relate to modern feminism are presented logically and accurately. Has been effective in converting many to a pro-life position.
Massacre of Innocence goes where no pro-life presentation has gone before in "tearing the lid off abortion" to reveal the spiritual realities we must battle if we will bring an end to this crime. The presentation is absorbing, fast-paced, informative and incredibly devastating to any attempt to justify abortion.
"… an extraordinary statement … a powerfully articulate presentation about what abortion really means, and why a great and moral nation like the United States must not allow the slaughter to continue."
— Congressman Robert K. Dornan
Running time: 85 minutes
$19.95 — ORDER NOW!(We accept all major credit cards and PayPal.)
Click here for more information
The Four Keys to the Millennium (Book)
Foundations in Biblical Eschatology
By Jay Rogers, Larry Waugh, Rodney Stortz, Joseph Meiring. High quality paperback, 167 pages.
All Christians believe that their great God and Savior, Jesus Christ, will one day return. Although we cannot know the exact time of His return, what exactly did Jesus mean when he spoke of the signs of His coming (Mat. 24)? How are we to interpret the prophecies in Isaiah regarding the time when "the earth will be full of the knowledge of the LORD as the waters cover the sea" (Isa. 11:19)? Should we expect a time of great tribulation and apostasy or revival and reformation before the Lord returns? Is the devil bound now, and are the saints reigning with Christ? Did you know that there are four hermeneutical approaches to the book of Daniel and Revelation?
These and many more questions are dealt with by four authors as they present the four views on the millennium. Each view is then critiqued by the other three authors.
$12.95 — ORDER NOW!(We accept all major credit cards and PayPal.)
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Abortion Clinic 911 Calls (DVD)
Exposes the Dangers of Abortion to Women!
These shocking eyewitness accounts expose the dangers of abortion not only to unborn children, but to the health and lives women as well. An antidote to the smokescreens of the liberal media, these short clips show what really happens in and around abortion clinics.
Although the content is emotionally gut-wrenching, these videos have been used in church seminars and small groups to educate Christians on the abortion issue and to lead people toward a pro-life position. Contains 2 hours and 40 minutes of materials that can be shown separately.
Watch these pro-life videos on-line.
"These videos helped change my mind from pro-choice to pro-life. Your videos are what did it for me. I will be walking in next year's March For Life in San Francisco." — A. Jackson, California
"I was going to have an abortion until I saw your video. Praise Jesus!"
— M. Drew, YouTube Commenter
$4.95 — ORDER NOW!(We accept all major credit cards and PayPal.)
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Dr. Francis Schaeffer - How Should We Then Live? (DVD)
Special Two-Disc Set!
After 40 years of intense study and world-wide ministry, Dr. Francis Schaeffer completed his crowning work of scholarship – to present profound truths in simple film language. Dr. Schaeffer's brilliant analysis of the past and predictions for current trends have proven so uncannily accurate that this amazing series still feels contemporary almost three decades after its initial release. Ultimately, Schaeffer concludes that man's only hope is a return to God's Biblical absolute, the truth revealed in Christ through the Scriptures.
Available for the first time on DVD, this documentary spectacular also includes intimate in-depth conversations with Francis and Edith Schaeffer. With the on-disc study guide, this presentation forms a unique course of comprehensive study. While this series forms an innovative analysis of the past, this outstanding work is more than history. Each episode focuses on a significant era, yet speaks clearly to 21st-century man with answers for modern problems.
$49.95 — ORDER NOW!(We accept all major credit cards and PayPal.)


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Publications (110)376.68 Total impact
Article: Liver grafts from CD39-overexpressing mice are protected from ischemia reperfusion injury due to reduced numbers of resident CD4(+) T cells.[Show abstract] [Hide abstract]
ABSTRACT: Ischemia-reperfusion injury (IRI) is a major limiting event for successful liver transplantation, and CD4(+) T cells and invariant NKT (iNKT) cells have been implicated in promoting IRI. We hypothesized that hepatic over-expression of CD39, an ecto-nucleotidase with anti-inflammatory functions, will protect liver grafts after prolonged cold ischemia. CD39-transgenic (CD39tg) and wild type (WT) mouse livers were transplanted into WT recipients after 18 hours cold storage, and pathological analysis was performed 6 hours after transplantation. Serum levels of alanine aminotransferase and IL-6 were significantly reduced in recipients of CD39tg livers compared to recipients of WT livers. Furthermore, less severe histopathological injury was demonstrated in the CD39tg grafts. Immune analysis revealed that CD4(+) T cells and iNKT cells were significantly decreased in number in the livers of untreated CD39tg mice. This was associated with a peripheral CD4(+) T cell lymphopenia due to defective thymocyte maturation. To assess the relative importance of liver-resident CD4(+) T cells and iNKT cells in mediating liver injury following extended cold preservation and transplantation, WT mice depleted of CD4(+) T cells or mice genetically deficient in iNKT cells were used as donors. The absence of CD4(+) T cells, but not iNKT cells, protected liver grafts from early IRI. CONCLUSION: Hepatic CD4(+) T cells, but not iNKT cells, play a critical role in early IRI following extended cold preservation in a liver transplant model. (HEPATOLOGY 2012.).Hepatology 04/2013; 57(4). DOI:10.1002/hep.25985 · 11.19 Impact Factor
Article: On the need for porcine embryonic stem cells to produce Gal KO pigs expressing multiple transgenes to advance xenotransplantation research.Xenotransplantation 11/2010; 17(6):411-2. DOI:10.1111/j.1399-3089.2010.00611.x · 1.78 Impact Factor
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ABSTRACT: Xenotransplantation using porcine donors holds tremendous promise for alleviating the chronic shortage of human organ donors. However, transplantation from pigs into higher primates triggers a vigorous immune response involving complement activation and thrombosis. Hyperacute rejection can be prevented by using donors in which GalT, the gene responsible for the predominant target of anti-pig natural antibodies, has been deleted. Unfortunately, the adaptive response to GalT knockout (KO) organs has been difficult to immunosuppress. The focus has shifted to identifying additional genetic modifications that will extend xenograft survival beyond the several months currently achievable. Which gene(s) should be added to the GalT KO background is open to debate. Overexpression of a complement regulatory factor(s) seems a logical first choice, supported by recent in vitro data but not yet validated in preclinical models. The next obvious candidate would be an anticoagulant protein(s) to deal with the dysregulated coagulation that is almost invariably associated with xenograft rejection. Several potentially useful molecules have been identified, although this study is yet to be translated to the pig. Our understanding of the mechanisms of GalT KO xenograft rejection continues to grow, providing a rational basis for tailoring further genetic modification of the donor and immunosuppression of the recipient.Immunology and Cell Biology 02/2009; 87(3):203-8. DOI:10.1038/icb.2008.107 · 4.21 Impact Factor
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ABSTRACT: Xenotransplantation of non-human organs into human recipients has long been proposed as a possible strategy to overcome the acute shortage of donor organs. However, vascular organ transplants to humans from phylogenetically disparate species such as the pig are not currently possible due to a rapid rejection process termed hyperacute rejection. This process is initiated by the binding of host pre-formed 'natural antibodies' to the donor vascular endothelium, activation of the host complement system and activation or injury of the donor endothelial cells, leading to intravascular coagulation and loss of the graft due to ischaemic necrosis within minutes to hours of engraftment. Prevention of natural antibody binding and complement activation is viewed as paramount to preventing hyperacute rejection. Even if hyperacute rejection can be prevented, further barriers to successful discordant xenografts such as delayed xenograft rejection and a donor-directed cell-mediated rejection process will still represent major obstacles. This review examines recent advances being made in the various areas of xenograft research and the potential clinical application of pig-to-human xenografts that these strategies may bring.Nephrology 04/2007; 2(4):217 - 227. DOI:10.1111/j.1440-1797.1996.tb00091.x · 1.86 Impact Factor
Article: Blockade of the passive cell death pathway does not prevent tolerance induction to islet grafts.[Show abstract] [Hide abstract]
ABSTRACT: T-cell apoptosis is an important regulatory mechanism in transplant tolerance. The aim of this study was to identify specific apoptotic molecules important for tolerance induction. Mice expressing the human Bcl-2 molecule in T cells or Bim -/- mice were used as islet allograft or rat islet xenograft recipients and treated with CTLA4-Fc and MR1 costimulation blockade. hBcl-2 transgenic mice and Bim -/- accepted islet allografts and rat islet xenografts for more than 100 days, similar to wildtype controls. Changes in the dose of the CTLA4-Fc and MR1 did not lead to differences in graft survival and there were no differences in the percentage of CD4+ T cells expressing Fas, CD25, or undergoing apoptosis. Inhibition of the passive cell death pathway in T cells did not block tolerance induction, suggesting that the mechanism by which apoptosis regulates the alloimmune response is more complex than first thought.Transplantation 04/2007; 83(5):653-5. DOI:10.1097/01.tp.0000255592.09784.ba · 3.78 Impact Factor
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ABSTRACT: Purpose of review: The past year has seen several pig-to-baboon transplant studies using α1,3-galactosyltransferase-deficient donors. There are now sufficient data to begin to assess the impact of this important modification, and to review additional genetic strategies that may bring xenotransplantation to the clinic. Recent findings: Survival of pig heart and kidney xenografts can now be measured in months rather than weeks, and the introduction of α1,3-galactosyltransferase-deficient donors has removed the requirement for depletion of anti-galactose-α1,3-galactose antibodies. The main obstacle to even longer survival is the development of antibodies to as yet unidentified non-galactose-α1,3-galactose antigens. Analysis of rejected grafts indicates that these antibodies activate graft endothelium, and the resulting prothrombotic state is poorly controlled because endogenous porcine anticoagulants fail to efficiently regulate primate clotting factors. Manipulation of the donor or graft to express anticoagulant and immunosuppressive molecules has produced encouraging results in small animal models. It is conceivable that expression of these molecules in pigs, in combination with the existing α1,3-galactosyltransferase-deficient and complement regulator transgenic modifications, will result in stable long-term xenograft survival. Summary: The α1,3-galactosyltransferase-deficient pig has advanced the field and becomes the platform on which further genetic modifications are built.Current Opinion in Organ Transplantation 01/2007; 12(1):30-36. DOI:10.1097/MOT.0b013e328012b0bb · 2.38 Impact Factor
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ABSTRACT: Purpose of review: The success of islet allotransplantation has highlighted the need for an alternative source of islet tissue. This review looks at the current status of islet xenotransplantation and what progress has been made towards a clinical therapy. Recent findings: There has been substantial progress in preclinical studies of islet xenotransplantation. Pig islets have been shown to control diabetes in rhesus macaques beyond 100 days using strong immunosuppression. There have been advances in our understanding of the fate of islets after transplantation. Exposure of pig islets to human blood leads to the instant blood-mediated inflammatory reaction, a likely cause of early graft loss. Islets surviving this reaction face immunological rejection by anti-pig antibodies and cell-mediated rejection. There has been progress with novel immunosuppressive approaches. The use of local immunosuppression secreted by the graft utilizes the therapeutic option of genetically altering the pig to enhance graft survival. Summary: Our understanding of issues such as instant blood-mediated inflammatory reaction and rejection have led to new strategies to overcome these problems. What is required now is well-planned preclinical studies to test these and to develop a protocol that is suitable to clinical application.Current Opinion in Organ Transplantation 03/2006; 11(2):174-179. DOI:10.1097/01.mot.0000218932.27397.19 · 2.38 Impact Factor
Article: Prevention of hyperacute rejection in a model of orthotopic liver xenotransplantation from pig to baboon using polytransgenic pig livers (CD55, CD59, and H-transferase)[Show abstract] [Hide abstract]
ABSTRACT: The search for alternative sources for transplant organs leads us to the search for animals as an inexhaustible source of organs. The objective of this study was to analyze whether livers from polytransgenic pigs expressing the human complement regulatory proteins CD55 (hDAF), CD59, and alfa alpha1,2-fucosyltransferase (H-transferase), protected against hyperacute rejection after orthotopic liver xenotransplantation to a baboon and also to study pig liver function in a nonhuman primate. Nine liver transplants from pig to baboon were divided into two groups: a control group (n = 4) of genetically unmodified pigs and an experimental group (n = 5) of pigs transgenic for CD55, CD59, and H-transferase as donors. All the donating piglets obtained through hysterectomy were maintained in specific pathogen-free conditions. The selection of transgenic pig donors followed demonstration of transgene expression using monoclonal antibodies (antiCD55, antiCD59) and immunohistological studies on liver biopsies. All animals in the control group developed hyperacute rejection with survival rates less than 16 hours without function of transplanted livers. In the experimental group none of the animals suffered hyperacute rejection. Survival in this group was between 13 and 24 hours. The livers were functional, producing bile and maintaining above 35% prothrombin activity. Only in one case was there primary dysfunction of the xenograft. Polytransgenic livers for complement regulatory proteins prevent hyperacute rejection when xenotransplanted into a baboon.Transplantation Proceedings 12/2005; 37(9):4103-6. DOI:10.1016/j.transproceed.2005.09.186 · 0.95 Impact Factor
Article: RECOMBINANT HUMAN ANTITHROMBIN III HAS PROTECTIVE EFFECTS IN PIG-TO-PRIMATE RENAL XENOTRANSPLANTATIONNephrology 02/2002; 7(1). DOI:10.1046/j.1440-1797.2002.00007-1-59.x · 1.86 Impact Factor
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ABSTRACT: A retrospective analysis of transgenesis rates obtained in seven pronuclear microinjection programs was undertaken to determine if a relationship existed between the amount of DNA injected and transgenesis rates in the pig. Logistic regression analysis showed that as the concentration of DNA injected increased from 1 to 10 ng/microl, the number of transgenics when expressed as a proportion of the number liveborn (integration rate) increased from 4% to an average of 26%. A similar relationship was found when the number of molecules of DNA injected per picolitre was analysed. No evidence was obtained to suggest either parameter influenced integration rate in mice when the same constructs were injected. The number of transgenics liveborn when expressed as a proportion of ova injected (efficiency rate), increased as DNA concentration increased up to 7.5 ng/microl and then decreased at 10 ng/microl for both species suggesting that at this concentration DNA (or possible contaminants) may have influenced embryo survival. The relationship between efficiency and the number of molecules injected per picolitre was complex suggesting that the concentration at which DNA was injected was a better determinant of integration and efficiency rates. In conclusion, the present study suggests that transgenes need to be injected at concentrations of between 5 and 10 ng/microl to maximise integration and efficiency rates in pigs.Transgenic Research 01/2002; 10(6):523-31. DOI:10.1023/A:1013007329936 · 2.28 Impact Factor
- Transplantation Proceedings 11/2001; 33(7-8):3053-4. DOI:10.1016/S0041-1345(01)02305-3 · 0.95 Impact Factor
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ABSTRACT: The involvement of the vascular endothelium in a large number of diseases supports the importance of vascular-specific gene delivery for their treatment. The hereditary hemorrhagic telangiectasia type 1 is an example of a vascular inherited disease (OMIM 187300). This is an autosomal dominant vascular disorder originated by mutations in the endoglin gene and associated with frequent epistaxis, telangiectases, gastrointestinal bleedings, and arteriovenous malformations in brain, lung and liver. Here, we address for the first time the possibility of using in vivo gene transfer to target endoglin expression to the vasculature. The promoter of the endothelial gene, ICAM-2, was used to generate transgenic animals which demonstrated endothelial expression of endoglin. Next, the promoters of the human endothelial genes, endoglin and ICAM-2, were inserted upstream of the human endoglin cDNA, and the resulting constructs were systemically or locally delivered, demonstrating endoglin expression in the vessel walls of liver, lung and skin. These gene transfer experiments represent an initial step in the treatment of the hereditary hemorrhagic telangiectasia type 1 by gene therapy, and suggest that endoglin and ICAM-2 promoters can be used to deliver other genes to the endothelium specifically.Gene Therapy 07/2001; 8(12):897-904. DOI:10.1038/sj.gt.3301468 · 4.20 Impact Factor
Article: Profound coagulopathy associated with pig-to-primate xenotransplants: How many transgenes will be required to overcome this new barrier?Transplantation 12/2000; 70(9):1273-4. DOI:10.1097/00007890-200011150-00003 · 3.78 Impact Factor
Article: Anti-alpha 1,3-galactose-mediated hyperacute rejection of vascularized transplants in a small animal modelTransplantation Proceedings 12/2000; 32(7):2075. DOI:10.1016/S0041-1345(00)01574-8 · 0.95 Impact Factor
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ABSTRACT: Pig-to-primate vascularized xenografts undergo hyperacute rejection (HAR). This results from pre-formed xenoreactive antibodies directed against galactose-alpha1,3-galactose (alphaGal) in the donor organ and activation of the complement cascade. We describe an in vivo murine model of HAR using a BALB/c mice system devoid of histocompatibility or complement differences between donor and recipient to investigate in isolation, the effects of alphaGal epitope and anti-alphaGal antibody interactions in causing rejection of vascularized heart transplants. Gal KO mice were immunized with rabbit red blood cell membranes to induce high anti-alphaGal antibody titers that were predominantly IgM by ELISA (enzyme-linked immunosorbent assay). When alphaGal-expressing mice hearts were transplanted heterotopically into these recipients (n= 12), 67% of grafts rejected within 24 h, the majority within 16 h with histological features of HAR. In contrast, none of the grafts in the non-immunized Gal KO recipient control group (n=11) underwent HAR. Interestingly, approximately 50% of the remaining grafts in both the immunized and non-immunized Gal KO recipient group were rejected between 7 and 27 days by a rejection process characterized by a dense infiltrate of macrophage/monocytes, perivascular cuffing and tissue destruction similar to recent descriptions of delayed xenograft rejection (DXR). In addition, some grafts (21.5%) continued to survive in the immunized Gal KO recipients despite the presence of anti-alphaGal antibody and normal complement activity and these showed well-preserved myocardium when harvested whilst still functioning well at days 30 or 90. No rejection was seen when Gal KO donors were used in this system (n=4), nor when alphaGal-expressing BALB/c hearts were transplanted into alphaGal-expressing BALB/c recipients (n=5). This in vivo small animal model offers the opportunity to test a variety of strategies to overcome HAR prior to more resource intensive pig-to-primate studies, and may provide insights into the processes similar to DXR and accommodation.Xenotransplantation 12/2000; 7(4):237-46. · 1.78 Impact Factor
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ABSTRACT: It has been proposed that hyperacute rejection (HAR) of pig-to-primate vascularized xenografts is due in large part to ineffective regulation of recipient complement by pig complement regulatory proteins (CRPs), and indeed transgenic expression of human CRPs in pigs can prevent hyperacute rejection. However, at least one pig CRP (CD59) efficiently regulates human complement in vitro, suggesting that it is the level of expression of a particular CRP(s) rather than cross-species incompatibility that explains the HAR of porcine xenografts. We investigated the relative effectiveness of transgenically expressed pig and human CD59 in providing protection of mouse hearts from human complement in an ex vivo setting. Transgenic mice expressing pig CD59 or human CD59 under the control of the human ICAM-2 promoter, which restricts expression in tissues to vascular endothelium, were used. Hearts from mice expressing similar levels of pig CD59 or human CD59 were perfused ex vivo with 10% human plasma and heart function was monitored for 60 min. Sections of perfused hearts were examined for deposition of the membrane attack complex (MAC). Control nontransgenic hearts (n=5) were rapidly affected by the addition of human plasma, with mean function falling to less than 10% of the initial level within 15 min. In contrast, hearts expressing either pig CD59 (n=6) or human CD59 (n=8) were protected from plasma-induced injury, maintaining 31 and 35% function, respectively, after 60 min of perfusion. MAC deposition was markedly reduced in both pig CD59 and human CD59 transgenic hearts compared to nontransgenic control hearts. When highly expressed on endothelium in transgenic mice, pig CD59 provided equivalent protection to human CD59 in a model of human complement-mediated xenograft rejection. Thus supranormal expression of endogenous porcine CRPs may be a feasible alternative to the expression of human CRPs in preventing HAR of pig-to-primate xenografts.Transplantation 10/2000; 70(6):963-8. DOI:10.1097/00007890-200009270-00014 · 3.78 Impact Factor
Article: Synthetic peptides which inhibit the interaction between C1q and immunoglobulin and prolong xenograft survival.[Show abstract] [Hide abstract]
ABSTRACT: Acute vascular xenograft rejection (AVXR), also termed delayed xenograft rejection (DXR), occurs when hyperacute rejection (HAR) is prevented by strategies directed at xenoreactive natural antibodies and/or complement activation. We have hypothesized that AVXR/DXR is initiated in part by early components of the complement cascade, notably C1q. We have developed synthetic peptides (termed CBP2 and WY) that interfere with the interaction between C1q and antibody. CBP2 and the WY-conjugates were used as inhibitors of immunoglobulin aggregate binding to solid phase C1q. Inhibition of complement activation by the peptides of the classical system was determined using lysis assays with sensitized sheep red blood cells or porcine aortic endothelial cells as targets and of the alternate complement pathway using guinea pig red blood cells as targets. Two transplant models were used to study the effects of administering peptides to recipients: rat heart transplant to presensitized mouse, and guinea heart transplant to PVG C6-deficient rats. CBP2 and WY-conjugates inhibited immunoglobulin aggregate binding to C1q. The peptides also inhibited human complement-mediated lysis of sensitized sheep red blood cells and porcine aortic endothelial cells in a dose-dependent manner and the WY-conjugates prevented activation of the alternate complement pathway as shown by inhibition of guinea pig red blood cells lysis with human serum. In addition, the use of the peptides and conjugates resulted in significant prolongation of xenograft survival. The CBP2 and WY peptides exhibit the functional activity of inhibition of complement activation. These peptides also prolong xenograft survival and thus provide reagents for the study of the importance of C1q and other complement components in transplant rejection mechanisms.Transplantation 10/2000; 70(5):828-36. DOI:10.1097/00007890-200009150-00021 · 3.78 Impact Factor
Article: Renal xenografts from triple-transgenic pigs are not hyperacutely rejected but cause coagulopathy in non-immunosuppressed baboons.[Show abstract] [Hide abstract]
ABSTRACT: The genetic modification of pigs is a powerful strategy that may ultimately enable successful xenotransplantation of porcine organs into humans. Transgenic pigs were produced by microinjection of gene constructs for human complement regulatory proteins CD55 and CD59 and the enzyme alpha1,2-fucosyltransferase (H-transferase, HT), which reduces expression of the major xenoepitope galactose-alpha1,3-galactose (alphaGal). Kidneys from CD55/HT and CD55/CD59/HT transgenic pigs were transplanted into nephrectomised, nonimmunosuppressed adult baboons. In several lines of transgenic pigs, CD55 and CD59 were expressed strongly in all tissues examined, whereas HT expression was relatively weak and did not significantly reduce alphaGal. Control nontransgenic kidneys (n=4) grafted into baboons were hyperacutely rejected within 1 hr. In contrast, kidneys from CD55/HT pigs (n=2) were rejected after 30 hr, although kidneys from CD55/CD59/HT pigs (n=6) maintained function for up to 5 days. In the latter grafts, infiltration by macrophages, T cells, and B cells was observed at days 3 and 5 posttransplantation. The recipients developed thrombocytopenia and abnormalities in coagulation, manifested in increased clotting times and an elevation in the plasma level of the fibrin degradation product D-dimer, within 2 days of transplantation. Treatment with low molecular weight heparin prevented profound thrombocytopenia but not the other aspects of coagulopathy. Strong expression of CD55 and CD59 completely protected porcine kidneys from hyperacute rejection and allowed a detailed analysis of xenograft rejection in the absence of immunosuppression. Coagulopathy appears to be a common feature of pig-to-baboon renal transplantation and represents yet another major barrier to its clinical application.Transplantation 07/2000; 69(12):2504-15. DOI:10.1097/00007890-200006270-00008 · 3.78 Impact Factor
Article: Naturally acquired anti-alpha Gal antibodies in a murine allograft model similar to delayed xenograft rejection.[Show abstract] [Hide abstract]
ABSTRACT: Antibodies directed against galactose-alpha1,3-galactose (alphaGal) are believed to play an important role in the pathogenesis of delayed xenograft rejection (DXR). This study was designed to determine whether alpha1,3-galactosyltransferase-deficient (Gal KO) mice can naturally acquire a sufficient anti-alphaGal titre to cause the delayed type rejection of alphaGal-expressing hearts. Gal KO mice of various ages were assessed for anti-alphaGal antibody levels. alphaGal-expressing hearts were transplanted heterotopically into these mice and monitored daily. Rejecting and surviving hearts were evaluated histologically. In Gal KO mice greater than 6-month-old, 64% had an anti-alphaGal antibody titre above the background level. When wild-type alphaGal-expressing hearts were transplanted into this group, 45% of grafts rejected within 5 to 13 days. Histological examination of the rejected hearts displayed marked tissue damage and an inflammatory infiltrate of predominantly macrophage/monocytes. Surviving grafts showed preserved morphology. Like humans, Gal KO mice naturally develop anti-alphaGal antibodies with age. The titre in these mice was sufficient to cause a "delayed-type" rejection of a significant proportion of alphaGal-expressing cardiac grafts. This model thus provides an opportunity to investigate the role of naturally acquired anti-alphaGal antibodies in the pathogenesis of DXR.Xenotransplantation 03/2000; 7(1):42-7. · 1.78 Impact Factor
- Transplantation 12/1999; 68(11):1630-1. DOI:10.1097/00007890-199912150-00004 · 3.78 Impact Factor
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The Herbfarm
Displaying all 17 articles
Seattle's Next Hot Chefs 2014
Best Restaurants 2012
Six of Seattle's Kitchen Interns Share their Tales
Food News Roundup
Neighborhood Food News: Trophy Celebrates the Girl Scouts, Everywhere Else Celebrates St. Patrick's Day
Food and Drink Events
Nosh Pit Weekly Planner
Critic's Notebook
The Herbfarm Brings Back its Tree Feast
Best Restaurants 2011
Seattle Best Restaurants 2011
Bizarre Moments in Drinking
The Herbfarm's Purloined Port
Wine Enthusiast Publishes America's 100 Best Wine Restaurants 2011
The Things You Learn on Twitter
The Vesper at The Herbfarm
The Herbfarm Announces New Pastry Chef
Herbfarm Chef de Cuisine Takes Over Christina's on Orcas Island
Leaves, needles, bark
Tree Eating at The Herbfarm
Nosh Pit Recommends
Nosh Pit Recommends: Halloween Dinners
The Herbfarm's 100-Mile Dinner
Dept. of Six Courses
Herbfarm Fourth of July
Dept. of Quiches and Frittatas
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Displaying all 17 articles


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ID Artikel: 938818 - Melihat produk di mana artikel ini berlaku.
Diagnose and fix the problem automatically
Note If you would rather fix this problem yourself, go to the "Let me fix it myself" section.
Similar issues that the MATS package fixes
(https://support.microsoft.com/kb/2415237/ )Can't preview pictures in Windows Photo Gallery in Windows Vista
(https://support.microsoft.com/kb/930102/ )Image transition issues in Windows Photo Gallery in Windows XP or in Windows Vista
For more information about other issues that the MATS package fixes, go to the "Other issues that the MATS package fixes" section.
When you start a slide show in Windows Photo Gallery on a computer that is running Windows Vista, pictures in the slide show are not displayed.
When you start a slide show, Windows Vista uses the Windows Experience Index ratings for Graphics to determine whether to use the DirectX Exclusive mode or the GDI+ mode to draw the images. If the DirectX Exclusive mode is used to draw the images, the progressive scan mode is always used. However, the display may not support the progressive scan mode or the non-interlaced scan mode in the current resolution. In this situation, you experience the issue that is described in the "Symptoms" section.
Note Some displays only support the interlaced mode in specific resolutions. For example, many plasma and LCD televisions use the 480i mode or the 1080i mode. In these examples, the letter "i" signifies "interlaced."
Let me fix it myself
Important This section, method, or task contains steps that tell you how to modify the registry. However, serious problems might occur if you modify the registry incorrectly. Therefore, make sure that you follow these steps carefully. For added protection, back up the registry before you modify it. Then, you can restore the registry if a problem occurs. For more information about how to back up and restore the registry, click the following article number to view the article in the Microsoft Knowledge Base:
(https://support.microsoft.com/kb/322756/ )How to back up and restore the registry in Windows
To fix this problem, use one of the following methods:
Method 1Use a display that support progressive mode in the selected resolution.
Method 2Edit the registry to force Windows Vista to use the GDI+ mode. To do this, follow these steps:
How the MATS package works to fix this problem
Click here to understand how the MATS package works to fix this problem
Other issues that the MATS package fixes
(https://support.microsoft.com/kb/930097/ )Computer is slow when Windows Photo Gallery displays TIFF images that do not fit into one page in Windows Vista
(https://support.microsoft.com/kb/2415238/ )Color issues in the print preview of an image in Windows Photo Gallery in Windows Vista
(https://support.microsoft.com/kb/2009298/ )Can't download albums in Windows Live Photo Gallery after upgrading from Windows Vista to Windows 7
(https://support.microsoft.com/kb/944221/ )Windows Live Photo Gallery freezes or can't start
(https://support.microsoft.com/kb/939395/ )An image and its background become yellow in Windows Photo Gallery in Windows Vista
(https://support.microsoft.com/kb/2425702/ )A screen saver that displays pictures stops working in Windows
ID Artikel: 938818 - Kajian Terakhir: 29 Februari 2012 - Revisi: 6.0
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For a home away from home on your luxury getaway, look no further than these unique destinations.
A Bazaar Caper: Bored to Death Subterfuge
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Teen Mom
Dalis Connell's Mother Is Diagnosed With Stage 3 Cancer
We have some sad news to report today, Teen Mom fans.
Dalis Connell, the current girlfriend of Maci Bookout's baby daddy Ryan Edwards, took to Twitter today to share some painful news.
The college junior tweeted:
Normally I wouldn't do this bc I don't like sympathy but could everyone please say a prayer for my mom? She was diagnosed with— Dalis Connell (@dalispaige) August 8, 2012
Stage 3 cancer & it's been weighing heavy! But I know— Dalis Connell (@dalispaige) August 8, 2012
#prayerworks :) thanks yall.
We're so sad to hear this news and we're keeping Dalis's mom in our thoughts.
Dalis and Ryan have been dating for more than a year now and this pretty model seems to be a great help with baby Bentley.
Feel free to share your well wishes to Dalis below!
Wanna chat with fellow Teen Mom fans? Join the discussion on our Teen Mom Facebook page!
Follow @TeenMomWetpaint on Twitter
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2009 Award Winners ATMOSPHERIC RESTAURANT OF THE YEAR 2009
Chez Hans
This is a very special award, because it invariably goes to an establishment that is really outstanding in every way – and has that special extra 'something' that makes a great atmosphere to showcase the whole operation, so that every visit is sure to be memorable.
It's often partly down to the building itself, or the way it has been converted or decorated, and that's certainly the case this year, as - although many others have since followed suit - the idea of running a restaurant in a church was highly original when this one opened in 1968.
And it is a wonderful setting – but it would be nothing without the people who have dedicated themselves to creating a really fine restaurant here - Hans-Peter Matthia, and now his family, especially his son Jason who returned from working in some of London's finest kitchens to join him in the business ten years ago and now runs it with his wife, Louise.
Their energy and talent have added greatly to the atmosphere of this famous restaurant - and its continued status as the leading restaurant in a wide area seems assured.
Show me all 2009 Award Winners
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Arts News
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Fireflies put on spectacular light show
Those ubiquitous synchronous fireflies are once again putting on a brief, but jaw-dropping light show in the Great Smoky Mountains.
Park spokesman Molly Schroer, who attended Wednesday night's viewing along with about 1,000 curious firefly gawkers in the Elkmont area of the national park, said the illuminated aerial display that occurs about this time each year is as spectacular as ever.
It's actually part of an elaborate mating ritual by the fireflies, which are also called lightning bugs.
"It's like a disco in the sky," said Schroer.
"It's neat the way it gets going very slowly. At one point, lights start flashing and then it goes black for eight or nine seconds. More and more fireflies start coming out and it just pops up around you. It just pulsates."
Schroer said the fireflies take center stage each night at about 9:30 to perform their flash dance as a way of attracting mates.
"It's about 11:30 when they shut it off and they're done with their mating."
Park officials are continuing organized viewing sessions of the fireflies through Wednesday for the weeklong event.
Parking passes that allow visitors to park at the Sugarlands Visitor Center cost $1.50 and are available online at www.recreation.gov.
Remaining passes go on sale at 10 a.m. each day for the following night's viewing.
Firefly enthusiasts are whisked by five shuttles from the visitor center to the viewing area at Elkmont for $1 per person. The shuttle service is the only way for most visitors to get to the Elkmont area during the viewing period. However, visitors staying in the Elkmont Campground can walk from the campsite to attend the event.
Schroer said Elkmont is a favorite haunt of the fireflies because of its elevation and the high moisture content in the area.
"Elkmont just so happens to have a high population," she said.
Synchronous fireflies, which are actually beetles, are one of at least 19 species of fireflies living in the park.
They are the only species in America that can synchronize their mostly greenish-yellow, flashing light patterns.
Each species of firefly has a signature flash pattern that helps males and females recognize each other.
Peak flashing season in the Smokies is normally during a two-week period in late May to mid-June.
Park officials instituted organized viewing sessions in the mid-2000s after large crowds became unmanageable and detracted from the firefly viewing experiences.
"Once we started to manage the event, the numbers (of people) had to go down, but the visitor experience has improved greatly over that time," said Schroer.
Last year, Schroer said that 179 parking passes per day, which can include up to six people per vehicle, were issued.
She said the count for this year's event is 200 per day so far.
Last year's event attracted people from 48 states.
Sadly, Schroer said, the annual choreographed spectacular is a last hurrah of sorts for the fireflies.
"After they mate, they lay their eggs and die," said Schroer.
A sad final act, but it's a process that ensures another eye-popping light show will go on next June.
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