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Publications (26)142.53 Total impact
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ABSTRACT: The skin biopsy is considered one of the most important tools in dermatology. Two primary reasons a clinician may perform a skin biopsy are either to establish a diagnosis or to evaluate therapy. The objective of this study was to critically assess the value of the skin biopsy as a diagnostic test for inflammatory dermatoses. One hundred consecutive skin biopsy specimens where an inflammatory dermatosis was queried were reviewed. To assess the diagnostic ability of the skin biopsy, the frequency with which a correct diagnosis was made based on histopathological analysis alone was recorded, that is, an initial "blind" diagnosis made without clinical data. Once this was recorded, the clinical history was provided and a posthistory diagnosis reached. The posthistory diagnosis was then compared with the final working diagnosis in the patient case notes. In 55% of cases, histology was able to provide a prehistory specific diagnosis. In 31% of cases, histology was not able to provide a specific diagnosis but could provide a differential diagnosis. In two thirds of these (20 of the 31 cases), the diagnosis was reached posthistory with clinicopathologic correlation. In 12% of cases, histology could only provide a pattern analysis, and in 2% of cases, only a descriptive report could be issued. In 13% of cases, the biopsy provided the final working diagnosis, which had not been considered clinically. The skin biopsy for inflammatory dermatoses is clearly a worthwhile investigative procedure. Prehistory blind histology based on microscopic data provided an accurate diagnosis correlating to the working diagnosis in 53% of cases. The diagnostic boundaries of dermatopathology are such that in an additional 25 cases (25%) a diagnosis was reached with aid of clinical data proving the importance of providing a well-thought-out differential diagnosis. Overall, in 78% of cases, histology with the aid of clinical information was able to provide an accurate diagnosis correlating to the working diagnosis.The American Journal of dermatopathology 07/2009; 31(4):350-3. DOI:10.1097/DAD.0b013e31819b3e0c · 1.43 Impact Factor
Article: Patients with both basal and squamous cell carcinomas are at a lower risk of further basal cell carcinomas than patients with only a basal cell carcinoma[Show abstract] [Hide abstract]
ABSTRACT: The rate of development of further basal cell carcinoma (BCC) after first presentation is highly variable. The mechanisms that determine this phenotypic difference are unclear. We assessed the risks of developing a subsequent BCC in patients who developed a BCC and a squamous cell carcinoma (SCC) and compared them with patients who developed a BCC only. In all, 1040 patients who developed BCC only were compared with 140 patients who developed BCC and SCC to see whether the latter group included a high proportion of risk phenotypes (eg, male sex and fair skin). We then compared the number of BCCs developing per year in the two groups (174 BCC only and 71 BCC/SCC) during a 5-year period after initial BCC presentation. The BCC/SCC group demonstrated a significantly lower BCC/year rate than BCC only group. The rate of development of further BCC during 5-year follow-up was lower in the BCC/SCC group because a smaller number of patients developed subsequent BCC and not because the same proportion of patients developed lesions but in smaller numbers. After 5 years of follow-up, 51.1% of BCC and 74.6% of BCC/SCC cases were free from a subsequent BCC. Logistic regression analysis corrected for age at initial presentation confirmed that patients with BCC/SCC were less likely to develop a further BCC during the 5 years after initial presentation (P = .001, odds ratio = 0.31, 95% confidence interval 0.15-0.63). Because of the large patient group and long study follow-up from the date of the index BCC or SCC, not all data were obtained. Where this is the case, the number of patients for whom the information is available is provided. Patients who develop a BCC are similar to patients who develop both a BCC and SCC, confirming the overlap of causative factors. Patients who develop both a BCC and SCC are less likely to develop BCCs compared with patients who develop BCC only.Journal of the American Academy of Dermatology 06/2009; 61(2):247-51. DOI:10.1016/j.jaad.2009.03.015 · 5.00 Impact Factor
Article: Seven-year prospective study of nonmelanoma skin cancer incidence in UK renal transplant recipients[Show abstract] [Hide abstract]
ABSTRACT: Nonmelanoma skin cancer (NMSC) causes significant morbidity and mortality posttransplantation. We examined the annual incidence of NMSC in U.K. renal transplant recipients (RTRs). A total of 269 (95% of potential population) RTRs of skin type I-IV were recruited into a prospective study of NMSC incidence between 1998 and 2006. A total of 244 (91% enrolled) RTRs were screened on at least one occasion. The mean incidence per year of NMSC was 7.82% (SD: 1.84), comprising a mean (SD) incidence per year of squamous cell carcinoma 3.45% (1.36), basal cell carcinoma 3.58% (1.17), and Bowen's disease 2.52% (0.91). The risk of developing NMSC increased with duration posttransplantation: the mean incidence per year of NMSC was 3.27% (0.53) in RTRs <5 years posttransplantation, 5.86% (3.1) in RTRs 5-10 years posttransplant, and 11.1% (1.85) in those >10 years posttransplant. Relatively low NMSC incidence rates within the first 5 years posttransplantation suggests that duration posttransplantation may determine the optimum frequency of surveillance of RTRs in the United Kingdom.Transplantation 08/2007; 84(3):437-9. DOI:10.1097/01.tp.0000269707.06060.dc · 3.78 Impact Factor
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ABSTRACT: One previous study has shown a higher prevalence of sebaceous hyperplasia (SH) in patients with heart transplant on immunosuppressive drugs as compared with sex-matched control patients. We set out to compare the prevalence of SH in a cohort of patients undergoing renal transplant with age- and sex-matched control patients and to find any association with nonmelanoma skin cancer (NMSC) in these patients. In all, 117 patients with renal transplant and 117 age- and sex-matched control patients were screened for the prevalence of SH and NMSC. We found that 29.9% of our patients with renal transplant had SH; 16 of 35 (45.7%) of these patients had a history of NMSC as compared with 6 of 82 (7.3%) patients without SH (P < .001, odds ratio 10.7). In the age- and sex-matched control group, a total of 28 patients (23.9%) had one or more lesions of SH. This study is small and will require confirmation with larger cohort studies. In our cohort of patients with renal transplant we found a strong association of NMSC with SH. This association remained significant after correction of factors such as age, sex, skin type, and duration of transplant.Journal of the American Academy of Dermatology 12/2006; 55(5):878-81. DOI:10.1016/j.jaad.2005.09.041 · 5.00 Impact Factor
Article: Polymorphism in the nuclear excision repair gene ERCC2/XPD: association between an exon 6-exon 10 haplotype and susceptibility to cutaneous basal cell carcinoma.[Show abstract] [Hide abstract]
ABSTRACT: Cutaneous basal cell carcinoma (BCC) risk is mediated by interactions between ultraviolet radiation (UVR) and host factors, including DNA repair efficiency. We investigated the association between BCC risk and SNPs in exon 6 (c.466C > A, dbSNP238406:g.C > A; designated C/A156), exon 10 (c.932G > A, dbSNP1799793:g.G > A; designated G/A312), and exon 23 (c.2251A > C, dbSNP13181:g.A > C; designated A/C751) of the nucleotide excision repair gene, XPD (ERCC2; excision repair cross-complementing repair deficiency, complementation 2 [xeroderma pigmentosum D]). XPD genotype frequencies were not significantly different in 509 cases and 379 controls, although AA156 (odds ratio [OR]=0.61, 95% confidence interval [CI]=0.37-1.01, P=0.052) and AA312 (OR=0.65, 95% CI=0.40-1.05, P=0.08) were linked with reduced risk. A156-A312 and A156-A312-A751 haplotype frequencies however, were significantly lower in cases than controls (OR=0.12, 95% CI=0.05-0.31, P < 0.001; OR=0.10, 95% CI=0.03-0.33, P < 0.001). We confirmed the robustness of these findings by showing significant associations of the haplotypes with risk in two randomly selected equal sized groups of cases and controls and, using the false positive report probability (FPRP) approach (FPRP values < 0.001 and < 0.004, respectively). A156-A312 was similarly associated with reduced risk in subgroups, including cases with no family history of skin cancer, with only BCC on the head/neck, and those with a high rate of increase in BCC numbers. The association was not dependent on gender, age, or extent of UVR exposure. A156-A312 was found in 6.3% of controls and the corresponding risk haplotype, C156-G312 (OR=1.65, 95% CI=1.21-2.26, P=0.002) in 35.4% of controls. We interpret these data as showing that XPD SNP mediate susceptibility to BCC.Human Mutation 04/2005; 25(4):353-9. DOI:10.1002/humu.20158 · 5.05 Impact Factor
Article: Associations between ultraviolet radiation, basal cell carcinoma site and histology, host characteristics, and rate of development of further tumors.[Show abstract] [Hide abstract]
ABSTRACT: Patients with basal cell carcinoma (BCC) frequently develop further tumors during follow-up. We sought to elucidate the relative effects of pattern of ultraviolet radiation exposure, and site and histologic type of the first tumor, on the rate of increase in BCC numbers. We used negative binomial regression analysis to study the association of selected variables on the rate of increase in BCC numbers in 266 Caucasian patients who first presented with a tumor on the head/neck or trunk with nodular or superficial histology. Patients with an initial truncal BCC with superficial histology demonstrated significantly faster increases in BCC numbers than did patients with other site and histology combinations. These data indicate that site and histology define subsets of patients with BCC.Journal of the American Academy of Dermatology 04/2005; 52(3 Pt 1):468-73. DOI:10.1016/j.jaad.2004.08.060 · 5.00 Impact Factor
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ABSTRACT: While sunlight is critical in basal cell carcinoma (BCC) pathogenesis the relationship between exposure and tumor site and histology is unclear. We determined if tumor site (trunk or head/neck) or histology (nodular or superficial) is determined by exposure pattern. In 66 cases with truncal and 362 patients with head/neck BCC at first presentation, average hours exposure/year, intermittency score, childhood sunburning and skin type were not significantly associated with tumor site or histology. However, often sunbathing was associated with a five-fold increased risk of truncal BCC. Average sunbathing score was significantly greater in 22 cases with truncal compared with 325 cases with head/neck nodular tumors and also in 44 cases with superficial truncal compared with superficial head/neck BCC. Thus, sunbathing determined tumor site but not histology.Cancer Letters 01/2005; 216(2):191-7. DOI:10.1016/j.canlet.2004.08.008 · 5.02 Impact Factor
Article: PTCH polymorphism is associated with the rate of increase in basal cell carcinoma numbers during follow-up: Preliminary data on the influence of an exon 12-exon 23 haplotype[Show abstract] [Hide abstract]
ABSTRACT: After first presentation with a basal cell carcinoma (BCC), patients demonstrate interindividual diversity in the rate of development of further BCCs (number/year of follow-up). The mechanism for this variation is unknown. In this study, we evaluated whether PTCH variants mediate this phenomenon. We used negative binomial regression analysis to identify associations between BCC numbers/year and host characteristics, parameters of exposure to ultraviolet radiation (UVR), and PTCH exon 12(1686) C/T, intron 15(2560+9) G/C, and exon 23(3944) C/T genotypes and haplotypes in 279 BCC cases who presented with an initial tumor on the head/neck. PTCH genotypes were not significantly associated with BCCs/year, although cases with two copies of the C1686-C3944 haplotype developed significantly fewer BCCs/year than those without this haplotype (rate ratio = 0.44; 95% CI = 0.27-0.71). Cases with one copy of T1686-T3944 developed more BCCs/year (rate ratio = 2.46; 95% CI = 1.27-3.97) than those without the haplotype. We found no significant associations between BCCs/year and the other PTCH haplotypes studied. We reexamined the association of C1686-C3944 with BCCs/year in a model that included UVR exposure parameters (sunburning in childhood, sunbathing score, intermittency of exposure between 40 and 60 years of age, exposure in hours/year) and skin type, gender, and age at first presentation. The association between C1686-C3944 and BCCs/year remained significant (rate ratio = 0.44; 95% CI = 0.26-0.73 for two copies of the haplotype). The data show that allelic variation in PTCH contributes to the rate of development of BCC.Environmental and Molecular Mutagenesis 01/2004; 44(5):469-76. DOI:10.1002/em.20068 · 2.55 Impact Factor
Article: Factors associated with nonmelanoma skin cancer following renal transplantation in Queensland, Australia.[Show abstract] [Hide abstract]
ABSTRACT: Caucasian renal transplant recipients living in Queensland, Australia, have the highest risk of nonmelanoma skin cancer in the world. To determine clinical and environmental factors associated with posttransplantation nonmelanoma skin cancer in Queensland. 361 Caucasian adult recipients completed a structured interview and full skin examination. Skin cancer details were obtained from hospital records. Squamous cell carcinoma was strongly associated with blue or hazel eyes, time resident in a hot climate, and pretransplantation squamous cell carcinoma; tumor numbers were associated with birth in a hot climate, childhood sunburn, pretransplantation actinic keratoses, and smoking. The risk of basal cell carcinoma was strongly associated with acute or intermittent sun exposure during childhood and pretransplantation basal cell carcinoma; numbers were associated with blue or hazel eyes, time spent living in a hot climate, and male gender. Clinical and environmental factors can be used to identify recipients at risk of nonmelanoma skin cancer in Queensland.Journal of the American Academy of Dermatology 10/2003; 49(3):397-406. DOI:10.1067/S0190-9622(03)00902-2 · 5.00 Impact Factor
Article: Combined effects of gender, skin type and polymorphic genes on clinical phenotype: use of rate of increase in numbers of basal cell carcinomas as a model system.[Show abstract] [Hide abstract]
ABSTRACT: Patients with a basal cell carcinomas (BCC) have an increased risk of further tumors. We studied the individual and combined impact of gender, skin type and allelic genes cytochrome P450 (CYP2D6), vitamin D receptor (VDR), tumor necrosis factor-alpha, TNF-alpha) on the rate of increase in BCC numbers after first presentation. Individually, male gender, skin type 1, CYP2D6 EM, VDR TT and TNF-alpha GG were associated with more BCC/year (rate ratio (RR) 1.20-1.36) while RR for associations of combinations of two, three and four variables were greater than in their reference categories (RR 1.32-1.90, 2.20-2.84, 3.06-5.49, respectively). The data show that different factors mediate the numbers of BCC/year in males and females and, the individual contributions of variables to risk is modest.Cancer Letters 02/2003; 189(2):175-81. DOI:10.1016/S0304-3835(02)00516-5 · 5.02 Impact Factor
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ABSTRACT: Renal transplant recipients are at high risk for multiple non-melanoma skin cancers (NMSC) that occur at a younger age and behave more aggressively. Consequently, the American Society of Transplantation has recommended that physicians conduct annual screenings for NMSC in this population. Few centres currently offer a dedicated surveillance programme. This article discusses a model for skin cancer surveillance in which a trained nurse works within a validated competency programme to provide annual skin surveillance and education in the renal transplant outpatient clinic.Nephrology nursing journal: journal of the American Nephrology Nurses' Association 07/2002; 29(3):257-9, 267. · 0.77 Impact Factor
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ABSTRACT: Malignant melanoma, the most serious cutaneous malignancy, has attracted substantial attention because of its rapidly increasing incidence and the poor prognosis of some tumours. Little is known of the genetic factors that mediate susceptibility to, and outcome of, sporadic malignant melanoma. Because of its role in mitogenesis, which is especially relevant to wound healing, tumorigenesis, and proliferation of epidermal tissues, epidermal growth factor (EGF) is an attractive candidate in which to look for genetic polymorphisms. We enrolled 135 white European patients with malignant melanoma and 99 healthy white European controls, and screened a selection of DNA samples for polymorphisms in the promoter and 5' untranslated region of the EGF gene by analysis. We then screened DNA samples from all participants for the identified polymorphism by restriction-fragment-length polymorphism (RFLP) analysis. In-vitro EGF production was measured in peripheral-blood mononuclear cells from 34 controls, and the results were compared with the individuals' EGF genotypes. We identified a single nucleotide substitution (G to A) at position 61 of the EGF gene. Allele frequencies in the controls were 56% EGF 61*A and 44% EGF 61*G. Cells from individuals homozygous for the 61*A allele produced significantly less EGF than cells from 61*G homozygotes (p=0.0004) or heterozygous A/G individuals (p=0.001). Compared with the A/A genotype, G/G was significantly associated with Breslow thickness (p=0.045) and with risk of malignant melanoma (odds ratio 4.9 [95% CI 2.3-10.2], p<0.0001). This study suggests that high EGF production might be important in the development of malignant melanoma.The Lancet 03/2002; 359(9304):397-401. DOI:10.1016/S0140-6736(02)07600-6 · 45.22 Impact Factor
Article: Susceptibility and modifier genes in cutaneous basal cell carcinomas and their associations with clinical phenotype.[Show abstract] [Hide abstract]
ABSTRACT: While ultraviolet radiation (UV) is critical in the pathogenesis of basal cell carcinomas (BCC), its role in determining the phenotypic variation shown by patients is unknown. Thus, patients manifest variation in BCC numbers, patterns of presentation and tumour site. We have used this diversity to classify patients into subgroups that are associated with different risks of developing tumours. Two phenotypes are particularly interesting. Firstly, presentation with clusters of BCC. These patients, termed multiple presentation phenotype (MPP), had two to five BCC at one presentation, suggesting rapid accrual over short periods of time. They comprised 15% of our 1200 BCC patients. A minority of patients demonstrated multiple clustering events, a phenomenon that is associated with a genetic pre-disposition. The second risk phenotype, characterised by tumours on the trunk, is also associated with a pre-disposition. Both phenotypes were characterised by a susceptibility to develop numerous BCC. Thus, all our patients with more than five BCC had one or both of these phenotypes. We are using a candidate gene approach to identify loci associated with risk of these phenotypes (susceptibility genes) and tumour numbers in them (modifier genes). Interestingly, we did not identify differences in UV exposure between patients with high- and low-risk phenotypes.Journal of Photochemistry and Photobiology B Biology 11/2001; 63(1-3):1-7. DOI:10.1016/S1011-1344(01)00194-4 · 2.80 Impact Factor
Article: Polymorphisms in glutathione S-transferases are associated with altered risk of nonmelanoma skin cancer in renal transplant recipients: a preliminary analysis.[Show abstract] [Hide abstract]
ABSTRACT: Non-melanoma skin cancer (NMSC) represents a significant cause of morbidity and mortality among renal transplant recipients, with tumors behaving more aggressively than those in nontransplant patients. Not all immunosuppressed patients develop NMSC, however, and in those that do, the rate of accrual and numbers of lesions vary considerably. Though ultraviolet light is critical, it is unlikely that this alone explains the observed phenotypic diversity, suggesting the possible involvement of genetic factors. Furthermore, although twin studies in nontransplant patients with NMSC suggest a low genetic component, several genes associated with susceptibility and outcome in these patients have been identified. Thus, having previously shown that polymorphism in members of the glutathione S-transferase (GST) supergene family is associated with altered NMSC risk in nontransplant patients, we examined allelism in GSTM1, GSTP1, GSTM3, and GSTT1 in 183 renal transplant recipients. GSTM1 null was associated with increased squamous cell carcinoma (SCC) risk (p = 0.042, OR = 3.1). This remained significant after correction for age, gender, and ultraviolet light exposure (p = 0.012, OR = 8.4) and was particularly strong in patients with higher ultraviolet light exposure (e.g., sunbathing score > 3, p = 0.003, OR = 11.5) and in smokers (p = 0.021, OR = 4.8). Analysis of the interaction between GSTM1 null and sunbathing score showed that the two factors were synergistic and individuals with both risk parameters demonstrated a shorter time from transplantation to development of the first SCC (p = 0.012, hazard ratio = 7.1). GSTP1*Ile homozygotes developed larger numbers of SCC (p = 0.002, rate ratio = 7.6), particularly those with lower ultraviolet light exposure and cigarette consumption. GSTM3 and GSTT1 also demonstrated significant associations, though some genotype frequencies were low. These preliminary data suggest that genetic factors mediating protection against oxidative stress are important in NMSC development in immunosuppressed patients and may be useful in identifying high-risk individuals.Journal of Investigative Dermatology 08/2001; 117(2):251-5. DOI:10.1046/j.0022-202x.2001.01357.x · 6.37 Impact Factor
Article: Basal cell carcinomas: association of allelic variants with a high-risk subgroup of patients with the multiple presentation phenotype.[Show abstract] [Hide abstract]
ABSTRACT: Previous studies have shown that patients who present at first or a later presentation with a cluster of new basal cell carcinoma (BCC) comprise a subgroup, termed multiple presentation phenotype (MPP), that is at increased risk of developing further lesions. In this study, we examined the hypothesis that patients who develop multiple clusters are a high-risk subgroup. We found, in a total group of 926 BCC patients, 32 patients with 2-5 BCC clusters (multiple cluster MPP) and 113 cases with only one cluster (single cluster MPP). Multiple cluster MPP cases had mean of 11.3 BCC compared with 3.7 in single cluster MPP cases during similar follow-up. Ultraviolet (UV) exposure in these groups was similar. We determined whether the multiple cluster MPP was associated with characteristics associated with sensitivity to UV or glutathione S-transferase (GST) GSTT1, GSTM1, cytochrome P450 (CYP) CYP2D6, tumour necrosis factor (TNF)-alpha and vitamin D receptor (VDR) genotypes previously associated with BCC presentational phenotypes. While the frequencies of blue eyes and male gender were greater in multiple cluster than single cluster cases, these differences were not significant. In multiple cluster cases, mean age at first presentation with single tumours occurred earlier and the frequencies of CYP2D6 extensive metabolizer (EM) (94.4%) and GSTT1 null (41.2%) were significantly greater (P = 0.028 and P = 0.004) than in single cluster cases (67.1% and 14.3%, respectively). The odds ratios for the individual associations of CYP2D6 EM and GSTT1 null with the multiple cluster MPP were relatively larger; 15.5 and 7.39, respectively. TNF-alpha and VDR genotypes were not associated with multiple cluster MPP. We propose that the MPP is not the consequence of excessive UV exposure but rather reflects the presence of a distinct BCC subgroup which is defined by combinations of risk genes.Pharmacogenetics 05/2001; 11(3):247-54. DOI:10.1097/00008571-200104000-00008
Article: Glutathione S-transferase GSTP1 and cyclin D1 genotypes: association with numbers of basal cell carcinomas in a patient subgroup at high-risk of multiple tumours.[Show abstract] [Hide abstract]
ABSTRACT: We previously described associations between basal cell carcinoma (BCC) numbers and allelic variants at loci that mediate host response to ultraviolet radiation (UV). These associations were largely exerted in cases with the multiple presentation phenotype (MPP). This phenotype describes patients who present at their first or a later presentation with a cluster of BCC (2-10 new BCC). Remaining BCC cases have the single presentation phenotype (SPP) and may develop more than one BCC but only have single new lesions at any presentation. We proposed that the MPP cases comprise a high-risk group as they suffer significantly more lesions than SPP cases. We are attempting to determine, in the total BCC case group and subgroups, how many genes influence BCC numbers and their relative importance. In this study, we assessed the influence of two further candidates, glutathione S-transferase GSTP1 and cyclin D1 (CCND1), on tumour numbers in a total group of 457 patients comprising MPP and SPP cases. The relative importance of these genes in comparison with occupational UV exposure and host response (skin type) was also considered. We found that the frequencies of GSTP1 genotypes based on the Ile105 and Val105-expressing alleles and CCND1 AA, AG, GG genotypes were similar in MPP and SPP cases and that there were no significant associations between GSTP1 or CCND1 genotypes and BCC numbers in the total or SPP groups. However, in the MPP cases, GSTP1 Val105/Val105 was associated with more tumours (P = 0.05, reference GSTP1 Ile105/Ile105). Inclusion of skin type and indoor/outdoor occupation in the negative binomial regression models did not alter the associations of these genotypes with tumour numbers. DNA from 258 cases was analysed to identify GSTP1*A (Ile105-Ala114), GSTP1*B (Val105-Ala114), GSTP1*C (Val105-Val114) and GSTP1*D (Ile105-Val114). In SPP cases, there was no association between BCC numbers and GSTP1 BB, though the association with GSTP1 BC approached significance (P = 0.09). In MPP cases, GSTP1 BC was associated with BCC numbers (P = 0.03). We also found that the interaction term, GSTP1 Val105/Val105 with CCND1 AA, was associated with BCC numbers in the total (P = 0.001) and MPP (P = 0.006) but not SPP (P = 0.68) groups. In a stepwise model including GSTP1 Val105/Val105, CCND1 AA and their interaction terms as well as GSTM1, GSTT1 and CYP2D6 genotypes, skin type 1 and gender, the combination of genotypes was the best predictor of BCC numbers. These data suggest that study of further genes involved in cell-cycle control and protection from oxidative stress will be useful, particularly in high-risk subgroups.Pharmacogenetics 09/2000; 10(6):545-56. DOI:10.1097/00008571-200008000-00008
Article: Basal cell carcinoma[Show abstract] [Hide abstract]
ABSTRACT: BACKGROUND Basal cell carcinoma (BCC) is characterized by marked interpatient variation in tumor accrual. The authors previously reported that presentation with a cluster of BCC is associated with an inherited predisposition to develop many additional lesions suggesting clustering is a critical event. A cluster is defined as the presence of two or more new, primary BCCs, at initial or later presentation.METHODS The authors recruited 927 cases and determined whether 1) clustering was an early or late event and 2) tumor accrual was altered after clustering.RESULTSIn the cases, 669 patients developed only 1 lesion, 112 patients presented more than once but with single lesions (single presentation phenotype[SPP]-more), 94 cases had a cluster at first presentation (multiple presentation phenotype [MPP]-cluster initial), and 52 cases first presented with 1 lesion but later had a cluster (MPP-cluster later). The authors found that 1) clustering occurred relatively late. The mean ages at first presentation with 1 BCC of the SPP-more (61.5 years) and MPP-cluster later patients (60.4 years) were similar although presentations with clusters in the MPP-cluster initial (67.6 years, P = 0.0002) and -cluster later cases (68.1 years, P = 0.002) occurred significantly later. 2) Clustering was associated with increased accrual. Thus, 26 patients (MPP-cluster later/a) in the MPP-cluster later group had a additional BCC postcluster. Mean accrual post-cluster (1.99 BCC/year) in these cases was significantly increased (P = 0.0001) compared with precluster accrual (0.39 BCC/year).CONCLUSIONS The authors found that the formation of BCC clusters represents a critical event such that after a cluster presentation, tumor accrual is significantly increased. Cluster presentation is a relatively late event suggesting reduced effectiveness in immune surveillance. Cancer 2000;89:1012–8. © 2000 American Cancer Society.Cancer 09/2000; 89(5):1012 - 1018. DOI:10.1002/1097-0142(20000901)89:5<1012::AID-CNCR10>3.0.CO;2-O · 4.90 Impact Factor
Article: Clinical risk factors associated with nonmelanoma skin cancer in renal transplant recipients.[Show abstract] [Hide abstract]
ABSTRACT: A single-center, cross-sectional, longitudinal study was conducted to determine the prevalence, annual incidence, and clinical risk factors for skin cancer in a white renal transplant population. One hundred eighty-two white patients (95% of population) with functioning allografts, a mean age at transplantation of 38.9 +/- 15. 6 (SD) years, and a mean follow-up of 8.5 +/- 6.3 years were interviewed and examined between May 1997 and June 1999. All case notes were carefully reviewed. Since transplantation, 16.5% of the patients had developed nonmelanoma skin cancer; 15.4%, actinic keratoses (AK); 53%, viral warts; and 1.6%, lentigo maligna melanoma (n = 3). Thirty-nine percent of the tumors were detected as a consequence of this study, and 20% of these occurred on covered body sites. The squamous cell (SCC)-basal cell carcinoma (BCC) ratio was 3.8:1. Eighty-two percent of the patients were examined a second time 12 months after the initial assessment. Using these data to identify new lesions, the annual incidence was calculated at 6.5%, increasing to 10.5% at more than 10 years posttransplantation. Duration of immunosuppression, older age at transplantation, presence of AK, male sex, and outdoor occupation were significantly associated with both SCC and BCC; SCC alone was associated with a history of having smoked tobacco. Early identification of those at greatest risk using a clinical risk profile may allow the development of more structured preventative and surveillance strategies than currently exist.American Journal of Kidney Diseases 08/2000; 36(1):167-76. DOI:10.1053/ajkd.2000.8290 · 5.76 Impact Factor
Article: Glutathione S-transferase GSTP1 and cyclin D1 genotypes: association with numbers of basal cell carcinomas in a patient subgroup at high-risk of multiple tumours[Show abstract] [Hide abstract]
ABSTRACT: We previously described associations between basal cell carcinoma (BCC) numbers and allelic variants at loci that mediate host response to ultraviolet radiation (UV). These associations were largely exerted in cases with the multiple presentation phenotype (MPP). This phenotype describes patients who present at their first or a later presentation with a cluster of BCC (2-10 new BCC). Remaining BCC cases have the single presentation phenotype (SPP) and may develop more than one BCC but only have single new lesions at any presentation. We proposed that the MPP cases comprise a high-risk group as they suffer significantly more lesions than SPP cases. We are attempting to determine, in the total BCC case group and subgroups, how many genes influence BCC numbers and their relative importance. In this study, we assessed the influence of two further candidates, glutathione S-transferase GSTP1 and cyclin D1 (CCND1), on tumour numbers in a total group of 457 patients comprising MPP and SPP cases. The relative importance of these genes in comparison with occupational UV exposure and host response (skin type) was also considered. We found that the frequencies of GSTP1 genotypes based on the Ile105 and Val105-expressing alleles and CCND1 AA, AG, GG genotypes were similar in MPP and SPP cases and that there were no significant associations between GSTP1 or CCND1 genotypes and BCC numbers in the total or SPP groups. However, in the MPP cases, GSTP1 Val105/Val105 was associated with more tumours (P = 0.05, reference GSTP1 Ile105/Ile105). Inclusion of skin type and indoor/outdoor occupation in the negative binomial regression models did not alter the associations of these genotypes with tumour numbers. DNA from 258 cases was analysed to identify GSTP1*A (Ile105-Ala114), GSTP1*B (Val105-Ala114), GSTP1*C (Val105-Val114) and GSTP1*D (Ile105-Val114). In SPP cases, there was no association between BCC numbers and GSTP1 BB, though the association with GSTP1 BC approached significance (P = 0.09). In MPP cases, GSTP1 BC was associated with BCC numbers (P = 0.03). We also found that the interaction term, GSTP1 Val105/Val105 with CCND1 AA, was associated with BCC numbers in the total (P = 0.001) and MPP (P = 0.006) but not SPP (P = 0.68) groups. In a stepwise model including GSTP1 Val105/Val105, CCND1 AA and their interaction terms as well as GSTM1, GSTT1 and CYP2D6 genotypes, skin type 1 and gender, the combination of genotypes was the best predictor of BCC numbers. These data suggest that study of further genes involved in cell-cycle control and protection from oxidative stress will be useful, particularly in high-risk subgroups.Pharmacogenetics and Genomics 07/2000; 10(6):545-556. · 3.45 Impact Factor
Article: Basal cell carcinoma: Tumor clustering is associated with increased accrual in high risk subgroupsCancer 01/2000; 89(5):1012-1018. DOI:10.1002/1097-0142(20000901)89:53.0.CO;2-O · 4.90 Impact Factor
Top Journals
Keele UniversityNewcastle-under-Lyme, England, United Kingdom
WWF United KingdomLondinium, England, United Kingdom
University Hospital Of North Staffordshire NHS Trust
Stoke-upon-Trent, England, United Kingdom
- Department of Dermatology
Staffordshire and Stoke-On-Trent Partnership NHS TrustNewcastle-under-Lyme, England, United Kingdom


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Sport, Concert and Theater tickets are hot and Frontrow.com has tickets to all your favorite events, including the Miami Heat Games, College Football and Super Bowl. We can get you "In the door" or the best seats to all games and events. Talk to one of our specialists or order online 24/7. Frontrow.com has a solid reputation of 22 years in the business selling tickets. Front row can get you tickets for all the, Playoffs and all NBA Games.
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Front Row is a quality ticket broker for all concerts, theater, and sporting events. Front Row sells the finest Step Show packages and tickets. If tickets you are searching for are not available, please check back as we always update and list new tickets in our huge inventory. Step Show schedules are on our web site. Just click to see our real-time online concert, sport and theater tickets.
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New Pittsburgh Courier
Rick Ross rocks Step Show during Atlanta Greek Picnic at Morehouse
New Pittsburgh Courier
ATLANTA – The 2015 Atlanta Greek Picnic (AGP2015) was in full throttle mode on the campus of Morehouse College as rap impresario detonated the stage during his performance following the ultra-popular $10,000 step show.
and more »
Rick Ross rocks Step Show during Atlanta Greek Picnic at Morehouse
ATLANTA – The 2015 Atlanta Greek Picnic (AGP2015) was in full throttle mode on the campus of Morehouse College as rap impresario detonated the stage during his performance following the ultra-popular $10,000 step show.
and more »
Chicago Defender
Rick Ross rocks Step Show during Atlanta Greek Picnic at Morehouse
Chicago Defender
ATLANTA – The 2015 Atlanta Greek Picnic (AGP2015) was in full throttle mode on the campus of Morehouse College as rap impresario detonated the stage during his performance following the ultra-popular $10,000 step show.
and more »
University Press
FAU Student Alleges Gang Rape at Step Show After Party
University Press
Last month, at a party following FAU's annual Step Show, a female FAU student told Boca Raton Police "she was pulled behind a curtain by several men who raped her." But police just announced the allegations in a news release today. "She reported the ...
and more »
New York Daily News
Florida Atlantic University student gang raped at 'step show' after-party: cops
New York Daily News
A Florida college student was gang raped by several men at an off-campus party at an events center last month after she became separated from her friends, Boca Raton police said Friday. The Florida Atlantic University student attended a "step show" on ...
and more »
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subset: commoncrawl


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You can now invite anyone to meet at your favorite Starbucks.
Limited-time feature
53 year old man | San Francisco, CA, USA | Seeking women 35-51 within 10 miles
SF native
Just looking for a woman who stays healthy, is reasonably fit, and is easy to communicate with. Most important, she is positive. The rest will take care of itself. I'm currently self-employed, taking care of personal financial investments. Some photos are from a 2011 trip to Costa Rica. I enjoy following and watching baseball, soccer, and the NFL. It would be great to meet a woman who has some interest in these things as well. I also have many interests beyond sports as listed below. In fact, people who know me would say that I tend to be on the "brainy" side. I enjoy keeping up with international news and getting into discussions about it. I'm always getting into new projects. When I get interested in something, I've been known to get totally focused on it. My latest fascination is with editing Wikipedia pages. I live on the far west side of SF, so it would be easier if you lived in the city or nearby in Marin/Peninsula. The basic information in my profile is true, because I don't want to waste anybody's time. I look forward to meeting a special woman who turns out to be the right match.
Coffee and conversation , Dining out , Movies/Videos , Music and concerts , Exploring new areas , Playing sports , Travel/Sightseeing , Watching sports
Other types of exercise, Running, Tennis / Racquet sports, Walking / Hiking
I exercise 1-2 times per week.
I don't believe in astrology
I like Dogs
Middle of the Road
Beach Chalet, Cliff House, Pacific Cafe, Ocean Beach, Lands End, Golden Gate Park; Stinson Beach.
visiting with friends; tennis, reading, travel.
Economist, WSJ, SF Chronicle, GoogleNews
Z{{Cta}} {{#if HasMoreInfo}} ?{{CtaSecondary}} {{/if}}
|What he is looking for
|5'7" (170cms)
|5'0" (152cms) to 5'7" (170cms)
|Body type:
|About average
|Slender, About average, Athletic and toned
|Blue, Green, Hazel
|Dark brown
|Auburn / Red, Black, Light brown, Dark brown, Blonde, Dark blonde
|No Way
|No Way
|Social Drinker
|Never, Social Drinker, Moderately
|Self-Employed / Entrepreneur
|No preference
Individual financial investor
|I'll tell you later
|No preference
|Never Married
|Never Married, Widow / Widower, Divorced
|Have kids:
|No preference
|Wants kids:
|White / Caucasian
|White / Caucasian
English, Scottish, German
|Spiritual but not religious
|Agnostic, Atheist, Spiritual but not religious
Episcopalian family. Culturally I identify with it somewhat, but I'm not religious.
|English, French
|Some college
|Some college, Associates degree, Bachelors degree
Finished two years at UC Berkeley


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Apple grants top execs $60M retention stock bonuses through 2016Apple's recent filings with the Securities and Exchange Commission outline stock bonuses worth up to $60 million each, intended to retain top executives through at least 2016.
The filings detail grants of 150,000 shares for each of six senior vice president falling under the SEC's definition of directors, officers, and principal stockholders: general counsel Bruce Sewell; senior vice president of Operations Jeffrey Williams; worldwide product marketing SVP Philip Schiller; chief financial officer Peter Oppenheimer; hardware engineering SVP Robert Mansfield; and iOS software SVP Scott Forstall.
At current market prices, 150,000 shares would be worth $60 million, but grants don't begin to vest until June of 2013, and the second half of the grant isn't available until March 2016, contingent upon the executives staying with Apple over the next half decade.
A smaller grant for 100,000 shares was awarded recently promoted Eduardo "Eddy" Cue, who was just awarded 100,000 shares at his promotion in September to SVP of Internet Software and Services, which put him in charge of the iTunes App Store, iAd, iBooks and iCloud services.
In August, Apple's chief executive Tim Cook was awarded a grant of a million shares of restricted stock that only begin to vest in 2016 and continue through 2021, similarly providing both an incentive to stay at Apple and a public assurance that Apple's leadership won't abandon the company to pursue other goals.
On Topic: Investor
- UBS calls Apple 'the Shake Shack of technology,' advises investors to buy in
- Apple to reveal fiscal Q3 2015 earnings on July 21
- Buyers opting for higher capacity iPhones, likely boosting Apple profits, RBC survey finds
- Apple on pace to sell 53M iPhones in June quarter, Apple Watch demand sustaining 'healthy' levels
- Subscription music service expected to boost iPhone experience, but not Apple's profits


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♪ Silver Moon, many thanks for nice opinion :) Greetings to Ankara, Anna
Ponuro, strasznie ... mi się podoba :)
Krzysztof Bochniak, lubię takie klimaty, chociaż zbyt często nie ma takiej gęstej mgły... Pozdrawiam, Anna
I like very much this photo, weel done! congratulations. Voted! Greetings from Spain.
Vanessa García Rivera, many thanks for nice visit :) I greet, :) Anna
I like this, nice shot.
Andrew Mckie, :) many thanks for nice visit :) I greet, Anna
very good photo
good atmosphere
best of
Greetings from Austria
Der weiße Wolf, many thanks for Your nice visit and comment :) Greetings to Austria, Anna
Photo taken in Pruszcz Gdański, Poland


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Striped Poplin Boyfriend Tunic: Button front blouse in stretch poplin features a relaxed, boyfriend-style fit with a touch of shaping added for a more flattering silhouette. Diagonal striped placket for an added touch of style.
Read what customers are saying about this product:
Rating: 4.00 out of 8 votes cast
Love It!
I ordered the Medium instead I should have ordered the Small! Runs large!
Andalusia, AL
Love it
Absolutely love the shirt, the print and the material. Just the right amount of stretch to make it so comfortable but still look great!
Runs large
I ordered the small, which is my usual size, but it was very large on me. I had to return the shirt.
Not for a curvy fit
I'm curvy in the bottom so not a good fit for me. Top was to big and the bottom area to snug. Would be great for a straight fit apple fit figure.
too small in hips
Well made blouse; very pretty; but did not fit. Too large in shoulders for me and too small in hips. Definitely not for a woman that is more pear shaped. (larger in hips than top). Had to return it and very sorry to do so.
Rockwall Tx
Size XL Runs Very Small
This is a pretty blouse, and seems to be well made. I typically wear a L or XL, but wanted this to be fairly loose, so ordered the XL. It fit far more like a M.
San Francisco
Nice shurt
The shirt runs very large its pretty you may want to order size down
This shirt runs huge. I ordered Medium. Even if I washed it (part cotton), it would be huge. Otherwise, the shirt is well made and really cute.
Abington, MA
Click here to read all of this product's reviews
*Sale and Clearance pricing is available on select colors and sizes and is valid on chadwicks.com purchases only. Hurry, quantities are limited! As a result, items shown may sell out. Click quick to get your favorites before they're gone!


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Marcia Davis: "A Swift Night Out" monitors declining chimney swifts
It's hard to believe how rapidly the familiar chimney swifts are disappearing from our summer skies. The chimney swift population is in a severe decline and is on the verge of becoming a threatened species.
With a body shape that's pointed at both ends, this easily identifiable bird (the only swift species to nest in the eastern U. S.) looks like a cigar with wings. It moves across the sky with rapid stiff wing beats as it searches for small flying insects to capture and eat in mid-air.
Every spring, fewer and fewer chimney swifts migrate north from South American wintering grounds. They face major problems when they reach the lower 48 states where 99 percent of all chimney swifts nest. The other one percent faces similar problems in Canada.
Building practices are changing and chimney swifts can't adapt. In the 19th and first half of the 20th centuries there was an ever-increasing supply of suitable open chimneys for nest sites. As the supply of chimneys increased after Europeans settled in America and cities developed the population of chimney swifts increased. Today, many older chimneys are disappearing as they are demolished, capped, or screened. Newer chimney designs may lack open tops and rough fire brick walls suitable for nest attachment. They can't be used by swifts. There aren't enough old-style chimneys that remain accessible for nesting. Also, little is known about factors on wintering grounds that could also contribute to the population decline.
North American Breeding Bird Surveys since 1966 show the breeding chimney swift population has suffered a 65 percent decline. Nearly two-thirds of the chimney swift population is already gone. From 1966 through 2010 the decline was 2.2 percent a year with an estimated 7.8 million chimney swifts remain.
"A Swift Night Out" is a continent-wide annual event to promote awareness of the plight of chimney swifts and the need for conservation. It's coming up the evenings of Sept. 6-8. As summer draws to a close chimney swifts gather in large migratory flocks that spend nights in communal roosts. Chimneys may contain from a few to hundreds or even thousands of swifts.
To participate in this event watch the sky at dusk for areas where swifts are feeding. Search for tall shafts, large chimneys and similar structures that swifts might enter and roost for the night. The sight of hundreds of chimney swifts swarming in the air at dusk, swirling in a funnel-shaped cloud, and finally peeling off from the flock to dive into an open chimney top is a true avian spectacle.
On the night of either Sept 6, 7, or 8 watch at a roost site starting about 30 minutes before sunset. Count or estimate the number of swifts that enter the structure. Record number of swifts counted, time, date, location, weather conditions, and a description of the site such a school chimney, church tower, warehouse, residence, chimney swift tower, etc.
Submit your information at www.chimneyswifts.org. This is a project of the Driftwood Wildlife Association, a volunteer organization promoting the conservation of chimney swifts through public education, preservation of nesting sites, and creation of new nesting and roosting sites.


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Nutrition for baby's first 1000 days
The first 1000 days, from conception until two years, are the most crucial for a baby's development. more
This article was written by Ella Walsh for Kidspot. Sources include Raising Children Network .
This article was created for Kidspot - Australia's parenting resource for during your pregnancy


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Single Panel Bronze Finish Cast Aluminum ScreenItem # HN-ES532
- Single-panel fireplace screen
- Cast aluminum with bronze finish
- Decorative leaf and scroll design
- Strong and broad base
- Dimensions: 42W x 33H inches
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IMAX Catarina Fireplace Screen
Arts and Crafts Style Curved Fireplace Screen
Reviewed by 1 customer
- Attractive Design
- Easy To Assemble
- Good Size
- Quality Materials
- Very Sturdy
- Well Constructed
Best Uses
- Decoration
Comments about Single Panel Bronze Finish Cast Aluminum Screen:
Very excited when the package arrived and was not disappointed when we opened the box. Assembly was very manageable and the product was of excellent quality.
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Sister Sky Coupons & Promo Codes
2 verified offers in May, 2014
We have 2 Sister Sky coupons for you to choose from including 1 sale, and 1 free shipping coupon. Latest offer: 'Free Shipping on $75+' The last time an offer was used was April 12, 2015.
Sign Up for Sister Sky Newsletters and Receive Exclusive News and Offers
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text:
Matthew Weiner on Directing Zach Galifianakis: "He Makes Me Laugh Just Walking Across the Room"
8:58 AM PDT 9/10/2013 by THR Staff
"All I had to do, honestly, was stay out of their way," Weiner said about working with Galifianakis and Owen Wilson in his new movie, You Are Here. "Owen, Amy (Poehler) -- there is so much of my laughter cut out of this movie offscreen. I have to be a good audience; that's the thing to be a good director to some degree."
Must Reads
Comic-Con: Which Movies Could Benefit From Panel Buzz?
Comic-Con 2015: THR's Full Guide to Parties in San Diego
CBS Entertainment Chief and "Loudmouthed Feminist" Nina Tassler Reveals the Strategy Behind 'Supergirl' Gamble
Paul Rudd and Marvel's Kevin Feige Reveal 'Ant-Man's' Saga, from Director Shuffle to Screenplay Surgery to Studio's "Phase Three" Plans
HBO's Real-Life Game of Thrones: The Fight to Stay Rich, on Top and Score Bill Simmons
Taraji P. Henson, Viola Davis and Drama Actress A-List Tackle Race, Sexism, Aging in Hollywood
Lena Dunham, Amy Schumer and Comedy Actress A-List in Raunchy, R-Rated Roundtable
Bob Odenkirk, David Oyelowo and Drama Actor A-List on Oscar Snubs, Bad Scripts and Getting Ignored by Robert Redford


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Home Winemaking
Best Practices in Selling
Wearing a smile, having a gift for gab, and dressing for success used to be essential tips for aspiring salespeople. Best Practices in Selling provides participants with up to date methods for selling through today's most frequently used media: the phone, email, texting, and social media.
Rapid Prototyping With Solidworks
This course will be a hands-on approach to learning SolidWorks software for additive manufacturing. In the course, you will learn the basics of 3D modeling, including building parts, assemblies, and testing your technical drawings to help each student understand what it takes to develop successfull design practices for 3D printing.
Sign in to create a new account, or access an existing one.
Browse our course listings of Degree & Academic, Life & Culture, Professional Advancement, and Special Programs. Please note that this symbol is used for online classes.
Search for Courses using the Class search bar.
Monday – Friday
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Cal Poly Extended Education
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Two groups to investigate off-duty officer's shooting
Armando Robledo Jr. was shot twice in the neck and chest at a Southside apartment complex early Sunday by Officer Jesse Hernandez, said Assistant Police Chief Ken Bung. Hernandez arrived about 5 a.m. at the apartment complex in the 3900 block of Holly Road, where he works security, Bung said.
A resident approached Hernandez and reported two residents causing a disturbance at a party at a unit in the complex, Bung said. Minutes later, the officer saw the two men in a parking lot, Bung said.
The men got into an older-model Cadillac, and Hernandez told the driver, Robledo Jr., to get out of the car, Bung said. Robledo Jr. backed the car up and pulled forward, hitting Hernandez and knocking him on top of the cars hood, Bung said.
Hernandez shot Robledo Jr. twice with his service revolver, Bung said. Hernandez called 911 and began CPR on the driver, Bung said. Robledo Jr. was taken to Christus Spohn Hospital Memorial where he was pronounced dead shortly after arriving.
A passenger in the car was arrested on suspicion of public intoxication.
The departments Criminal Investigation Division will investigate whether Robledo Jr.s death was a criminal homicide, and the Internal Affairs Division will investigate whether Hernandez acted according to the departments standard operating procedure, Bung said.
more to come for Tuesday's print edition
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Need Help? Call us at 1-800-566-8098.
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text:
Hamas Vows Revenge After 7 Members Killed
Hamas Vows Revenge After 7 Members Killed
Wrongly Imprisoned Brothers Sue Detectives and Cleveland
Unlock your personal NFL Now stream by signing in to NFL.com
The Islamic militant group Hamas that rules Gaza vowed revenge on Israel for the death of seven of its members killed in an airstrike early Monday morning in the deadliest exchange of fire since the latest round of attacks began weeks ago. Hamas' said "the enemy will pay a tremendous price," referring to Israel. The group said its men were killed by an Israeli airstrike on a tunnel used by the militants. Two militants from a different group were also killed in a separate strike.
Police detectives threatened a 12-year-old witness to make him offer false testimony in a murder case and fabricated statements by him, according to a federal lawsuit filed on Thursday by two brothers who spent decades in prison for a crime they didn't commit. The lawsuit, naming several living and deceased Cleveland police detectives and the city, also alleges it was common practice for detectives not to turn over notes, including witness statements, during investigations.
Authorities said, An Arizona man confessed to fatally shooting a Maricopa couple who disappeared more than a week ago, and whose bodies were found buried outside his home Wednesday. Pinal County Sheriff Paul Babeu said Thursday, 38-year-old, Jose Valenzuela, is charged with two counts of first-degree murder in the deaths of Michael and Tina Careccia, who were reported missing on June 22.
Colombian authorities say a homemade explosive has gone off in the capital's financial district, wounding five people. Col. Oscar Pinzon of the Bogota Metropolitan Police says there is no information on who might have set off Thursday's explosion. He describes the device as of being of medium power.
The rapper Sean "Diddy" Combs will not be charged with felony assault stemming from an incident involving a kettlebell weight at the University of California, Los Angeles, city officials said on Thursday, but he still may face a lesser penalty. 45-year-old, Combs, was arrested on charges of assault with a deadly weapon last month by campus police, and held in jail. Media reports said Combs was involved in an altercation with UCLA's football coach at the campus athletic facility.
NBC keeps the Heroes Reborn marketing campaign rolling with two more character posters, via TV Insider. The first poster features Kiki Sukezane as the sword-wielding 'Miko.' She's described in the official synopsis as "a unique and quiet girl looking for her missing father, but she hides an extraordinary secret that can be dangerous to her." The second poster features former Chuck and Thor: The Dark World actor Zachary Levi as 'Luke Collins,' a vigilante who lost someone special during a terrorist attack.
AWOLNATION - AWOLNATION LIVE Concert
Strung Out - Strung Out Concert
EDC Las Vegas - EDC Las Vegas 2015 Compilation
Electric Daisy Carnival in Pictures - Day 1
EDC Las Vegas - Highlights from Day 1 of Electric Daisy Carnival
Barenaked Ladies - One Week - Live from DTE Energy Music Theatre
Community Episode 1: Ladders
Community Episode 2: Lawnmower Maintenance and Postnatal Care
Community Episode 3: Basic Crisis Room Decorum
Community Episode 4: Queer Studies and Advanced Waxing
Community Episode 5: Laws of Robotics and Party Rights
Community Episode 6: Basic Email Security
Community Episode 1: Ladders
Community Episode 2: Lawnmower Maintenance and Postnatal Care
Community Episode 3: Basic Crisis Room Decorum
Community Episode 4: Queer Studies and Advanced Waxing
Community Episode 5: Laws of Robotics and Party Rights
Community Episode 6: Basic Email Security


text:
STAMFORD, Conn. -- Fairfield County's Chinese community is set to celebrate the Year of the Horse on Saturday, Jan. 25, in Stamford.
The celebration will take place at the 40th anniversary dinner dance at 5 p.m. at the Hilton Stamford Hotel. The dinner dance is organized through the Organization of Chinese Americans, Fairfield County chapter. The celebration honors the 40th anniversary of the founding of the Chinese community in Fairfield County.
Children from the Chinese Language School of Fairfield County will perform a Dragon Dance and the program features concert violinist Richard Lin and concert pianist Ms. Xiaohui Yang. Soprano Yvonne Cheng and the OCAFC Chorus will be singing a medley of songs and opera in Chinese, English and Italian. A 10-course Chinese banquet is followed by raffles and ballroom dancing.
Tickets can be purchased online at the event webpage for the 40th anniversary celebration.
- 1 New Scam Showing Up On Facebook Could Cost You Lots Of Money
- 2 Stamford EMTs Use Narcan For First Time To Save Man From Overdose
- 3 Police Search For Stamford Man In Armed Robbery Of Check-Cashing Business
- 4 Teen Killed After Being Hit By Car Crossing Road To Danbury Pizza Place
- 5 Rain Could Spoil July 4 Events, Celebrations In Stamford


text:
Showing 99 Results for jack black
College Football 2012 — Week 13 Preview
NFL 2012 Season — Week 11 Recap
NFL 2012 Season — Week Nine Recap
10 Things You Didn't Know About Halloween
Shakespeare described the "witching hour" as a time "when churchyards yawn and hell itself breathes out." Spooky! Equally esteemed author Washington Irving described Halloween night in his classic 'The Legend of Sleepy Hollow' as a setting full of "fearful shapes and shadows...amidst the dim and ghastly glare of a snowy night." Kids all across the country describe it as the night when the entire world gives them all the candy they can eat until they either pass out or develop early on-set diabetes.
20 Halloween Pumpkin Fails
Between your foolproof stencil of Justin Bieber's face and an endless supply of premium 99 cent carving tools, you probably envisioned yourself minutes away from that dreamy pop star pumpkin glowing all over your neighbors' jealous faces. What could go wrong?
Jack-o'-Lanterns, Witches and Costumes: The Ghoulish Truth About 10 Halloween Traditions
Halloween is more steeped in tradition than just about any other holiday, and the roots of those traditions are as varied and seemingly unconnected as a pumpkin and a bonfire.
We decided to take a look at a few of Halloween's most well-known customs. What do they all mean? Why do we celebrate Halloween by putting on bizarre outfits and asking strangers for candy? Who is Stingy Jack, and why does he haunt our dreams?
The 10 Most Haunted Places in America
As Halloween draws near, shut the lights off, grab your pet, a well-worn blanket, and curl up to read about some of the most spine-tingling and frightening places on Earth. As the ghost stories of each place draw you in, be aware of that disembodied footstep or strange rapping noise-it may just be a spirit trying to reach out to you!
Some Random Thoughts – From the Bird's Nest
This Day in Sports History — September 28
Here are just some of the notable sports moments that happened on September 28:
1920 — Shoeless Joe Jackson and seven of his teammates on the 1919 Chicago White Sox were indicted by a grand jury for allegedly throwing the World Series to the Cincinnati Reds. (More info.)


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Top Definition
AKA as Balanitis Swollen foreskin in the Orthopaedic surgery patient.
Wow!, Look at the Heffernan's Syndrome on that Ortho Patient!!!!! Holy F^#%in S*!T!!!!!!
by JMCG2222 December 12, 2011
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Videos tagged "iainbaxterand"
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Nov 5, 2011 – Jan 15, 2012 Iain Baxter legally changed his name to IAIN BAXTER& in 2005. He appended an ampersand to his name to underscore his belief that art is about connectivity, contingency, and collaboration with a viewer. In 1965 he formed a collaborative art-making entity titled IT Works, which subsequently evolved into N. E. Thing Company, a corporate-styled entity whose copresidents were BAXTER& and his then-wife, Ingrid. Producing a diverse array of projects that encompassed conceptually based photography, pioneering works of appropriation art, and gallery-transforming installations, the N. E. Thing Company offered a new model of art-making, allowing the artists to remain anonymous and masquerade in the guise of business people. Collapsing the boundaries between art, commerce, and everyday life, BAXTER&'s protean and peripatetic work has unfolded over five decades and proved difficult to locate within conventional critical or art historical narratives. A relentless emphasis on reaching out to the viewer, a core concern with ecology and the environment, and a belief that art must assume plural means and media, inform BAXTER&'s early credo: understanding that "art is all over." This exhibition seeks to appraise the remarkable achievement of this artist, and to position his contribution in relation to mainstream histories of conceptual art, photography, and installation art. Organized by the Art Gallery of Ontario mcachicago.org+ More details
IAIN BAXTER&: Information/Location, North Vancouver06:19
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Video of the making of the NVMA show IAIN BAXTER&: Information/Location+ More details
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This was a project in development for my senior level drawing course with Iain Baxter& at the University Of Windsor. The project was to create a self portrait. I have had a recent interest in Max/MSP/Jitter and thought to use the histograph abilities, taken from a live camera. I used 'face detect' from Open.CV to detect a person, which starts the rapid flow of colours as the screen projects the histograph one colour band at a time. The face detects also allows only one person to start the projection, if two or more faces are detected the projection will stop. Music: Boards Of Canada - 747+ More details
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The Tree House
Price for guests, Nights
2 reviews
Price for guests, Nights
Estimated nightly price based on a weekly stay. Excludes fees (if applicable). Enter your dates to see the total cost.
Apartment / 2 bedrooms / sleeps 5
Availability Your dates are available
Apartment / 2 bedrooms / sleeps 5
|Key Info
From this elegant Victorian conversion, central Oxford is a 15 minute stroll or 5 minute bus trip. The location, is minutes away from the trendy bars and restaurants in Jericho, and on the same road as a former president of the United States.
You will find this the ideal location from which to explore cental Oxford, London or the Cotswolds. You also have the option of off-street allocated parking.
|Sleeps up to 5, 2 bedrooms
|Will consider
|Corporate bookings, Long term lets (over 1 month)
|Car not necessary
|Nearest travel links
|Nearest airport: Heathrow 72 km, Nearest railway: Oxford 1.6 km
|Family friendly
|Great for children of all ages
|No pets allowed, No smoking at this property
Features and Facilities
|Internet access, DVD player
|Central heating, TV, Wi-Fi available
|Kettle, Toaster, Iron
|Dishwasher, Cooker, Microwave, Fridge, Freezer, Washing machine
|2 bedrooms, 1 bathrooms of which 1 Family bathrooms
|Double beds (1), Single beds (3), Dining seats for 5, Lounge seats for 5
|Linen provided, Towels provided
|Shared garden
|Parking, Not suitable for wheelchair users
|Further details indoors
Bedroom 2 can be configured as a king sized bed, as a twin room, or with 3 single beds, for families with young children.
|Further details outdoors
There is a possibility of allocated off-street parking for one car; please ask at time of enquiry if you need a parking space.
The Oxfordshire region
Oxford is one of our most famous and world renowned cities. There is a wealth of culture and history on your doorstep, including, the Oxford Colleges, The Ashmolean Museum, The Radcliffe Camera. It is the gateway to the Cotswolds and, either by car or coach, you can enjoy exploring the picture postcard traditional villages, like Burford, Stow and many others.
If and when you are wanting a break from culture and beauty, the shopping is great, and Bicester Village shopping outlet is only 20 minutes away.
Central Oxford
The apartment is only minutes walk from the trendy bustling area of Jericho, which features many bars and restaurants as well as an art house cinema. Oxford has two large theatres, and a variety of smaller drama and theatrical venues.
The Playhouse, Burton Taylor, and Apollo theatres are all within about 10 minutes walk.
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Craig M.
- 3 Years listed
55% Response rate
Calendar last updated:17 Apr 2015
Based in United Kingdom
- English


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One of the most common neighborhood disputes regarding real estate involves so-called party driveways, sometimes called common driveways. With a party driveway, the boundary line between the two neighbors runs lengthwise down the middle of the driveway. Each neighbor, therefore, owns one-half of the driveway. Each neighbor, however, has an easement or right to use the half of the driveway that the other neighbor owns. With that in mind, each neighbor's ownership of their share of the driveway is subject to the fact that they must share the use of their side of the driveway with the neighbor. Unless there exists an agreement to the contrary, the cost of maintaining and taking care of the driveway is equally shared by the neighbors. Finally, as a general rule, party driveways will both bind and benefit later owners of both properties.
Another neighborhood dispute often involves a house, garage, fence, etc., found to be located on the property of the next door neighbor. This is called an "encroachment". As a general rule, one neighbor may demand that a fence or even a building be moved if it encroaches on one's property. However, under a legal doctrine known as adverse possession, if a building or fence is in existence for a period of time (generally 21 years), that building or fence and the land within it may be subject to claim of ownership and the encroaching structures owner. This is called ownership by "adverse possession". While other conditions in additions to the passage of time must be met to successfully prove adverse possession, it can result in an individual actually owning the real estate he has illegally trespassed upon at the expense of his neighbor who had legally purchased it. 7/11
If you need an attorney and don't have one, the Lawyer Referral and Information Service can help.


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Researcher -Product/User — Atlassian — Sydney - Australia
Research is enormously valued at Atlassian, and we are looking for designers from all level of seniority to boost our team. As a UX researcher you'll be part of a dynamic group that does it all--early stage contextual inquiries, ethnography, and concept testing through usability studies and other methodology. This key role will set up and maintain research frameworks and internal engagement models for usability testing, surveys, interviews and requirements workshops.
Posted May 25, 2015
Product Designer — Atlassian — Sydney - New South Wales - Australia
Product design is enormously valued at Atlassian, and we are looking for designers from all level of seniority to boost our team. As a product designer at Atlassian you'll be responsible for ensuring that our users have a great experience with our products. You'll design elegant and delightful product experiences as part of an integrated team to help define the vision and roadmap for your product area.
Posted May 25, 2015
UX Designer — TheLadders — New York - New York - United States
The User Experience Designer at TheLadders is integral to the creative process and plays a pivotal role in the strategy, conception and design of TheLadders web and mobile products. The UX Designer at TheLadders will report to the Director of UX and Design. Preference will be given to people who demonstrate a combination of strategic, conceptual and UX design and UX research chops.
Posted May 22, 2015
UX Designer — Electronic Ink — Philadelphia - Pennsylvania - United States
The Senior Designer plays a key role in creating the design and user experience of various web-based applications, software and business systems. Senior Designers must have the ability to collaborate with fellow team members. They are expected to seek a understanding of every client's target audiences, users' behaviors, needs and expectations, and incorporate them into a comprehensive solution that addresses business goals.
Posted May 21, 2015
Design Researcher — Electronic Ink — Philadelphia - Pennsylvania - United States
Electronic Ink is looking for Contract Senior Design Researchers available for project work starting immediately. Candidates local to the Philadelphia area are preferred. The Senior Design Researcher is responsible for research-related engagements, including gathering product requirements, analyzing research data and applying this information to the design process, validating the usability of the resulting product, writing reports and developing supporting artifacts.
Posted May 21, 2015
Senior UX Designer / Consultant — Market Gravity — London - London - United Kingdom
With sales and prospects at an all-time high, we are currently searching for world-class UX designers to join our rapidly growing team. We're looking to hire people who are passionate about working with leading brands to design and launch new propositions and user experiences. It's not for everyone, we're only interested in risk takers with an entrepreneurial mindset who thrive on creating game changing innovation within big companies.
Posted May 21, 2015
Informatiom Architect — Dukat LLC — Edison - New Jersey - United States
The Information Architect is responsible for developing IA documentation (site maps, navigation models, content models) for web sites. The role of the information architect is to work directly with design, development and content teams to ensure consistency and continuity of overall categorization and product development strategies. A firm understanding of user-centered design processes and information architecture principles is essential.
Posted May 21, 2015
Senior UX Interaction Design — Acquia — Boston - Massachusetts - United States
You'll be joining a talented team of interaction designers and UX researchers creating breakthroughproducts for people developing rich digital experiences with Drupal. Our customers are a savvy, demandinggroup; you and this team are responsible for delivering best-of-breed enterprise-grade applications in a fast-paced, agile, startup-like environment.Acquia offers fabulous company benefits and a fast paced, highly motivated, enormously fun work environment, not to mention a career with
Posted May 21, 2015
UX Interaction Designer - Contract — Patriot Staffing & Services — Charlotte - North Carolina - United States
UX - Challenge accepted - how would you change the user experience for our client? Our clients is interested in what you can do for their client. Support the development of simplified, efficient, and consistent external and internal client technological experiences across the company footprint of applications and tools. Design specific applications and work with different product groups with the goal to create common user experiences. http://bit.ly/1dmIS2T
Posted May 21, 2015
Associate Director, Innovation and Design — NYC Mayor's Office of Operations — New York - New York - United States
As part of this unit, the Innovation and Design team leads innovation, design, and strategy for enhancements and new functionalities to the three core digital products: Accelerator, ACCESS NYC, and Worker Connect, in addition to creating new offerings in support of the equity and opportunity agenda. Joining this team is an opportunity to use your expertise in digital services to create meaningful impact and help improve the lives of millions of New Yorkers.
Posted May 20, 2015
User Experience Designer — Tradesy — Santa Monica - California - United States
You will, as a User Experience Designer at Tradesy, envision how people experience all of our products and articulate in a clear and compelling way that vision. You'll make sure all of the complexity and power under the hood of our technology is experienced by users through easily recognizable, accessible and empowering interfaces and interactions. You will bring these experiences to life from strategy and concept through to polish, while partnering with teams of Designers, Research
Posted May 20, 2015
UX Architect wanted to join a growing creative team — Every Interaction — London - London - United Kingdom
This is a real opportunity to carve out a leading role in a growing agency, and in time hire to build you own IA team. The person we hire will be pivotal and tightly integrated into the team to ensure we all work on solving problems together, ensuring there are plenty of intelligent minds in the circle.
Posted May 20, 2015
Creative Project Manager — Tekzenit — Irving - Texas - United States
The Creative Project Manager will be responsible for the coordination, implementation, execution, control and completion of creative projects guaranteeing consistency with brand strategy, commitments and goals.
Posted May 18, 2015
UX Strategist (full-time) — R2integrated — Baltimore - Maryland - United States
The UX Strategist will manage strategic planning for complex web and mobile projects for a wide array of clients in diverse verticals. The ideal candidate will be a creative thinker with a strong content creation background who is able to define the "why" and the "how" in order to create insight driven user experiences. Strategists are expected to be skilled and active listeners who are able to translate big-picture, strategic thinking into actionable recommendations that maximize results.
Posted May 18, 2015
Senior Experience Architect — Allen & Gerritsen — Philadelphia - Pennsylvania - United States
Our ideal candidate will, first and foremost, be a baller. But he or she will also excel at helping us work with our clients to solve their business issues with solutions that are both creative and ingenious. If you want to ride with us, it's also pretty important that you have an intense passion for how humans interact with the digital worlds around them – whether the experience is web, mobile, wearable, ambient, or some other crazy thing we don't even know about yet.
Posted May 18, 2015


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Our native-speaking qualified Arabic teachers can guide you and your group at your work or at home, at a time convenient to you. Classes can take place on any day of the week - even weekends - morning, afternoon or evening. If needs be, if meeting at your office or home is not suitable, you can take your lessons at the trainer's office. Study materials are supplied for you.
Arabic lessons of this type are broader and are aimed towards students with a variety of requirements. While all beginner level students will cover survival Arabic - needed for short visits to countries where English isn't widely spoken, or if you wish to 'go local'; those studying Arabic usually go in different directions at this point, depending on what they need. Those who have benefitted from these Arabic classes have been those investing in or buying property overseas, those married to overseas nationals, people setting off on a round-the-world trip, enthusiasts in Arabic culture, and those enthusiastic to pass a specific exam in Arabic.
These Arabic lessons are driven towards people who have a requirement to learn Arabic to bolster their work output. For novices, you will find it useful to learn basic greetings and business etiquette; and once you have become more proficient then reading and writing will come to the fore. Typical students include those concerned with import/export, those seeking work in multinational companies, international negotiations, and anyone working with international colleagues or administration. Even on our most rudimentary beginners lesson, students can expect to finish the lesson with decent telephone and e-mail Arabic, as well as a good enough grip on the language for a short trip to the country.
Lessons in Arabic are also accessible for 2 or more studying in tandem (Two-to-One Arabic Lesson or Small Group In-Company Arabic Lesson). All those involved must have around the same experience of the language, similar needs of areas of proficiency, and must be able to work at the same time and place. Bookings must be made for all students at the same time. Listen & Learn do not advise classes of more than 6-8 people, although In-Company Taster Arabic sessions can be run with as many as 12 people.
In written Arabic, nouns have three different cases and two genders; they can be singular, dual or plural, and unlike European languages, nouns also have a state - 'indefinite', 'definite' and 'construct'
Arabic shares many linguistic properties with Aramaic and Hebrew
There are around 206 million Arabic native speakers in the world
Arabic Testimonials
"I have recently completed my Arabic course with my extremely helpful, native speaking, and really qualified teacher. She helped me a lot with my basics in Arabic, and it was a wonderful experience for me!"
NashvilleIf Nashville spoke only one language, it would be that of the "rhinestone" sound of country music. Luckily enough for all those out there who are tone-deaf or musically un-inclined, Nashville speaks a whole range of other international languages. Experience the world of languages all from the comfort and familiarity of Nashville; it's all out there waiting for you! Learn Spanish, Arabic or Vietnamese in Nashville and find that opportunities for practical language exchange crop up in everyday life. There are also significant numbers of Kurdish, Lao and Somali speakers in Nashville. Speaking the languages of Europe, Asia and Africa, Nashville is the ideal location for kick-starting your foray into the languages of the world!


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Lucifer's Hammer
By Larry Niven; Jerry Pournelle
(Del Rey Books, Mass Market Paperbound, 9780449208137, 640pp.)
Publication Date: May 1985
List Price: $7.99*
* Individual store prices may vary.
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The gigantic comet had slammed into Earth, forging earthquakes a thousand times too powerful to measure on the Richter scale, tidal waves thousands of feet high. Cities were turned into oceans; oceans turned into steam. It was the beginning of a new Ice Age and the end of civilization. But for the terrified men and women chance had saved, it was also the dawn of a new struggle for survival--a struggle more dangerous and challenging than any they had ever known....
"Massively entertaining."
JERRY POURNELLE is an essayist, journalist, and science fiction author. He has advanced degrees in psychology, statistics, engineering, and political science.


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11 Teacher-Approved Crafts for School
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Back to School Album
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Remember the joy of the first day of school with this Back to School Album. Made using simple paper-folding techniques, this project is great for kids to do with their parents for at school for their first arts and crafts time! Let the kids decorate their mini album however they'd like, and fill it with photos, notes, and other memories from their first day back. This also makes a precious time capsule gift for when your little one eventually graduates high school or college.
Primary Technique: Paper Crafts
- Double sided cardstock
- Letter stickers
- School theme stickers
- Washi tape
- Ribbon
- Craft knife & Ruler
- Dry adhesive
- Fold 12"X12" double sided cardstock in half. Open turn quarter of a turn clockwise and fold in half again.
- Cut a slit on the fold line from the top edge to the center.
- Widen the slit by cutting a 1/16" on each side of the cut.
- Fold top left square towards the bottom. Fold top right square towards the bottom.
- Fold two squares towards the center.
- Embellish with Washi tape and stickers.
- Add ribbon around the folded mini album for closer.
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Do you want to make Ohio.com your homepage?
By Scot Lehigh
Boston Globe
Ronnie Wood (left) Mick Jagger (center) and Keith Richard of the Rolling Stones perform in concert at the TD Garden arena in June 2013 in Boston. (Photo by Bizuayehu Tesfaye/Invision/AP)
Click here to read or leave a comment(s) on this story.


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December 7, 2011
I know I'm getting cantankerous in my old age, but don't get me started about things like keyless start, backup cameras and "instant" fuel economy.
Tags: ignition trigger, Air Conditioning, fuel economy gauge
Author: Chris Brown | Posted @ Wednesday, December 7, 2011 12:00 AM | » Comments(1)
We offer e-newsletters that deliver targeted news and information for the entire fleet industry.
The expert, Mark Betner from CITGO, will answer your questions
The expert, Rence Oliphant from Hendrickson, will answer your questions
TruckTech+ Provides Diagnostics to Fleets and Dealers
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VentAiRator Vented Visors


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Offered for sale is a set of four early 19th century English garniture dessert comportes or compotes. They are a matched set and are hand painted in an unusual burgundy ribbon tied border hung with hand painted flowers. The set is enhanced with gilt borders and open branch handles.
The set is marked with puce colored pattern numbers and attributed to either Spode or Coalport. It is in excellent condition, perfect for display in a cabinet or on a sideboard. There is minor age-related gilt and enamel wear.
Size of 2 rectangular compotes: 2 3/4" Height by 11 7/8" Length by 9" Width
Size of 2 garniture compotes: 2 1/4" Height by 9 1/2" Diameter.
Antiques, Decorative Items, and Fine Art for everyone- from the new collector to the connoisseur
We are adding new hand picked treasures every week. To view them, be sure to check out "This Weeks Arrivals.".


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A new report by the Center for Reproductive Rights (CRR) calls on both the federal and state governments to address the growing threats against and stigmatization and abuse of abortion providers throughout the United States. The report is accompanied by a series of videos including interviews with providers, and an action campaign targeting Congress.
The best gift I could give to honor Dr. Tiller's life is to "come out" as an abortion provider to friends and family, to identify myself and the work I do with pride.
PBS has produced an exceptional segment about violence and harassment targeting abortion providers, asking whether Dr. George Tiller's killing was an act of domestic terrorism and what the effect of decades of violence has on women's access to the procedure.
In a resolution that passed 423 to 0, the House of
Representatives condemned the murder of my friend Dr. George Tiller. Now it is
the Senate's turn.
Senators Jeanne Shaheen, Amy Klobuchar, and Barbara Boxer
have introduced a Senate version of the House's resolution. They
need our help to convince their colleagues to sign on.
But these resolutions are just the beginning. Congress
has much more to do.
One of the last remaining providers of very late abortions in the country said it was an "outrage" the murder of Dr. George Tiller last week has led to his family's decision to close the clinic he ran in Wichita, Kan.
Dr. Marianne Knox is a young abortion provider working in the South — defying statistics, and the fear factor.
Now is the time to recognize the real threat to abortion providers and women seeking their services. Now is the time to recognize the extreme lack of abortion providers and resources for women. Now is the time to recognize Dr. Tiller as a hero, and perhaps in death he can truly change the face of the pro-choice movement and the future of abortion care.
Members of the reproductive health community, those working in clinics and as allies of clinics across the country, shared their shock and deep sadness at the loss of Dr. George Tiller today.
When women who regret their abortions take to the streets…
On National Abortion Provider Appreciation Day, we recognize that the threats to abortion providers have changed since the 1990s. Violent attacks have diminished. But state legislatures are still restricting and targeting providers.


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Originally written on Diehardsport | Last updated 12/7/12
PITTSBURGH - DECEMBER 27: Ray Lewis #52 of the Baltimore Ravens prepares for the snap during the game against the Pittsburgh Steelers at Heinz Field on December 27, 2009 in Pittsburgh, Pennsylvania. (Photo by Karl Walter/Getty Images)
As if anyone needed a reason to be more afraid of Ray Lewis when he was on the field. Lewis pulled a page out of Justin Tuck's playbook and is going with the new "shredder" facemask, to keep offensive players from grabbing at his facemask. It also helps that this look makes him look absolutely fierce. I'm still in awe that Lewis has returned to practice after tearing his triceps just over seven weeks ago, the man is a machine.H/T: Ravens Instagram
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How About Those Hoakies!!!!!!!!!!!!!!!!!!!!
How About Those Hoakies!!!!!!!!!!!!!!!!!!!!
UNC, Florida, UCLA, Ohio St., Wisconsin, Kansas, and probably Pitt will all have a strong case.
Should be a helluva NCAA tourney.
Matta = Really good
"I saw Wedding Crashers accidentally. I bought a ticket for Grizzly Man and went into the wrong theater. After an hour, I figured I was in the wrong theater, but I kept waiting. Thats the thing about bear attacks. They come when you least expect it."-Dwight K. Schrute
I'd like to see any other team in the country play UNC, Florida, and Wisconsin on the road, and not have their best big man against UNC and play better than OSU did. Except against Florida, where they got dominated.
If OSU can figure out a way to keep Butler and Lewis active and in the game while feeding Oden a ton, OSU will have a strong chance to make a big run come March.
Matta = Really good
By the way, my buddy in C-bus tells me that the talk around there is that Oden has been quoted lately saying that he wants to stay four years. I'll believe it when I see it...but wouldn't that be amazing. Could you imagine how monstrous he'd be as a senior? Yikes.
For every action there is an equal and opposite criticism.
Personally, I really hope OSU doesn't get a #1/2 seed in the tournament. I'm really hoping they can be a #4 seed or so. I think if OSU doesn't have a target on their back they can be the most dangerous.
OSU could also win the national championship and he would then have very little to prove on the college level and leave.
*IF* he comes back next season, OSU and UNC would be hands down the favorites to win it all next year. If he does or does not I sure hope they match UNC and OSU up in the ACC/Big Ten Challenge and let OSU host it, WOW!
OSU's team next year if Oden came back would simply be sickly deep.
PG - Conley Jr - So.
SG - Butler - Sr.
SF - Cook - So.
PF - Hunter - Sr.
C - Oden - So.
Terwilliger - Sr.
Lighty - So.
Madsen - So.
Koufus - Fr. (aka Dirk Jr.)
Diebler - Fr.
Lauderdale - Fr.
Turner - Fr.
Wallace - Fr.
That team is 13 deep. That is as deep and talented as what UNC throws out this season. I'd say Lauderdale, Wallace, and Diebler would get the least playing time of the freshman. Koufus is going to be a beast at 7'1" and can play the SF position.
Anyways, enough of the rant. OSU will be Top 5 no matter what Oden does next season. It is very bright in C-Bus with Matta around.
Matta = Really good
Ohio State's young group will just get better and better. Nobody will want to play them come tournament time.
"I came here to kick ass and chew bubble gum... and I'm all out of bubble gum."
- - Rowdy Roddy Piper
"It takes a big man to admit when he is wrong. I am not a big man"
- - Fletch
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