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Rules Rumors
NBA Commissioner Adam Silver said Thursday he is "on the fence" about intentional fouling away from the ball and expects the league to be "very engaged" about the tactic over the coming months. A day after the San Antonio Spurs sent the Clippers' DeAndre Jordan to the foul line 17 times in a playoff victory, Silver said he once favored a rule change but now isn't pushing for one. "I've gone back and forth," Silver said during a meeting with a group of Associated Press Sports Editors. "I've sat in meetings with some of the greatest players like Michael Jordan, Larry Bird who said that players should learn to make their free throws and it's part of the game. At the same time, it doesn't make for great television, so I'm on the fence right now."
The "away from the ball foul" rule, which is designed to thwart the "hack-a-whoever" strategy. Right now players such as the Clippers' DeAndre Jordan and Rockets' Dwight Howard (among others) may just get fouled and sent to the line because they struggle to knock down the two free throws. Under the new rule the coach of the fouled team can send any player on the court to the line for one of those free throws. That essentially makes it highly likely one of the shots gets made, which makes employing the "hack" strategy far less attractive.
Other rule changes coming to the D-League this year: The "advance" rule — once in the final two minutes of the fourth quarter, a team can advance the ball for a half-court throw-in (after a made basket or the ball going out-of-bounds off the opponent) without having to call a time out. Teams can also substitute in this window. Right now coaches save a couple of time outs to use in the final minutes of a game so they can advance the ball and get the players they want on the court, often the coaches draw up a play in there. Now once per game they don't have to call a timeout (and slow the game down) to do it.
The D-League, on top of being a minor league for the NBA (one which will by the end of Wednesday already have two call ups this season) but it is a laboratory of NBA experimentation. Whenever the league wants to see how a new rule might work in practice, they try it out in the D-League. That means this year D-League coaches will get a challenge flag (well, the right to challenge a call). That's one of a few interesting rule changes for this season the D-League announced Wednesday.
As I reported last year, Adam Silver and other top NBA officials are at least curious about the 40-minute length of FIBA games. Shorter games would mean fewer advertising windows in a very literal sense, but that doesn't necessarily translate into a long-term revenue reduction or unanimous opposition from network executives. Scarcity can increase per-minute value, especially if ratings go up. There is some belief within the NBA that brisker games could indeed prove more popular among younger fans. Shorter games might also prove to be more unpredictable, since the favorite would have about 15 fewer possessions with which to assert its superiority. Unpredictable games generally rate well, and the NBA is (rather easily) the most predictable of the four major U.S. sports leagues on a game-to-game basis.
The NBA has struck a groundbreaking partnership with Brazil's top domestic basketball league in which the two will share best practices, marketing strategies, and player development techniques, per sources familiar with the situation. The goal of the NBA's partnership with Liga Nacional de Basquete is to increase the sport's profile in Brazil, deepen cooperation between the NBA and top FIBA leagues, and expand the NBA's international brand. The agreement could be announced by early next month, and the NBA will likely obtain an equity stake in the LNB as part of the deal, per sources. The deal will likely have the NBA sending both cash and people into Brazil for at least two years. The LNB was formed in late 2008 as a way of placing the top 16 Brazilian teams under the same competitive umbrella.
NBA stars LeBron James and Dirk Nowitzki reacted to the league's decision to schedule a 44-minute game saying it's the regular season, not the games, that should be shortened. Is that a widespread opinion among players? We asked 28 NBAers to find out. Result: They are split on the debate with 42.9 percent saying regular season should stay at its usual 82 games and 57.1 suggesting that's too much.
The idea to shorten the game was conceived in an off-season coaches' meeting in Chicago. Dallas Mavericks coach Rick Carlisle initially made the suggestion, according to Nets coach Lionel Hollins, the NBA jumped at the idea, and the Nets and Celtics were willing to be the test subjects. The league has no plans to try it again this season, although the D-League could be used to conduct further experiments. But even with a small sample size, the NBA hopes to get a better idea of all the potential externalities. "We're taking a look at a lot of different things regarding our game and if we can find ways that can make it more appealing, or make it better. Then we hope that we're able to ascertain what those things are," said NBA president of basketball operations Rod Thorn, the former general manager of the New Jersey Nets.
Jones elaborated on how the reserves would be impacted. "If there's 44 minutes in a game and teams decide to play their starters the same exact way, you limit four minutes a game from a reserve," he explained "If you extrapolate that over a course of a season, you're talking 328 minutes. That's a lot when you're talking about value. I think anytime you start talking about shortening games, extending games, there has to be a thorough conversation between the league and the players. Limiting minutes has a bigger impact on reserve players."
Cleveland's James Jones, who happens to serve as the secretary-treasurer of the National Basketball Players Association, says he doesn't support the reduction of minutes being that it will have a negative effect on the reserve players. "The structure of the games, the amounts of minutes that are played are working condition issues for us because it limits how much time our guys actually have to work," Jones told Northeast Ohio Media Group. "It's a major concern for us because there is an attempt, or at least an examination to see whether or not you limit the minutes of the games. And that has a direct impact on player's opportunities to work and to provide for themselves."
"No. It's not the minutes, it's the games," James said. "The minutes doesn't mean anything. We can play 50-minute games if we had to. It's just the games. We all as players think it's too many games. In our season, 82 games is a lot. But it's not the minutes. Taking away minutes from the game is not going to shorten the game at all. "Once you go out and play on the floor, it don't matter if you play 22 minutes — like I may be playing tonight — or you're playing 40 minutes," James added. "Once you play, it takes a toll on your body. So it's not lessening the minutes, I think it's the games."
The length of the season? Nowitzki and James would be all for shortening it significantly, although they realize that business realities make that extremely unlikely. "I think you don't need 82 games to determine the best eight in each conference," Nowitzki said Wednesday. "That could be done a lot quicker, but I always understand that it's about money, and every missed game means missed money for both parties, for the league, for the owners, for the players. I understand all that, and that's why I don't think it's going to change anytime soon."
The NBA will experiment with a 44-minute game Sunday when the Nets play host to the Celtics "to examine the flow" of a shorter contest. "It's interesting," Thibodeau said. "I'm curious myself how it plays out. In some ways, the technology (we have) has been great but it also has prolonged the game. "(Commissioner) Adam Silver is very open-minded. There's part of me that likes (the idea) a lot. And there's also a part of me that thinks about the tradition of the game and the records and the history. That's where there's conflict. But the intent is good."
"We have looked at everything that we do and are taking a fresh look at all the different things we do," NBA president of basketball operations Rod Thorn said. "One of the things that keeps coming up is our schedule and the length of our games. … Our coaches talked about it, and a lot of them seemed to be in favor of at least taking a look at it. We talked with our competition committee, and they were in favor of taking a look at it." The NBA will look how a 44-minute game impacts length of the game, player-substitution patterns and flow of the game to determine if there's a better experience. "Let's get some empirical evidence regarding this and take a fresh look at it," Thorn said.
The Brooklyn Nets and Boston Celtics will play a 44-minute game — four minutes shorter than a regulation NBA game — Sunday at the Barclays Center. Playing four 11-minute quarters is a one-time preseason experiment and only exploratory. However, at the recent NBA coaches' meeting in Chicago, the length of games was a topic, and it was suggested the NBA take a look at shortening games.
Around last season's All-Star break, preliminary chatter began among the league's basketball operations folks and rule geeks about the prospect of reducing all trips to the free-throw line to a single foul shot. D-League president Dan Reed and Houston Rockets general manager Daryl Morey were the closest thing to co-sponsors of a bill. Nobody was proposing anything to be fast-tracked, but an imperative to figure out ways to shorten pro basketball games gave the idea some life as something to consider implementing in the D-League.
The concept was this: A player fouled in the act of shooting or in a penalty situation would attempt only a single free throw. If that player was shooting a 2-point shot or in a penalty situation at the time of the foul, the free throw attempt would be worth two points. If that player was fouled in the act of launching a 3-point shot, he'd go to the line for a single shot worth three points.
The NBA is expanding the area that must be clear behind the basket and cutting the number of photographers along the baseline in an effort to improve player safety. The new regulations, calling for an extra foot of open space on both sides of the basket stanchion, were sent to teams Tuesday by league president of operations Rod Thorn and executive vice president of team marketing and business operations Amy Brooks in a memo that was obtained by The Associated Press.
NBA issues statement on the idea of adding a 4-point line: From league spokesman Tim Frank: "No one at the NBA,nor the competition committee, has had any serious conversations about increasing the size of the floor or adding a 4-point line. Rod Thorn and Kiki VanDeWeghe were entertaining a line of questioning about out of the box ideas and ESPN.com chose to make a story that doesn't exist."
During a sit-down TrueHoop TV interview with our own Henry Abbott, Thorn was asked about the chances that a 4-pointer — as outlandish as it may seem — could be brought to the NBA at some point. In a Per Diem column last month, I advocated for the introduction of a 4-point line 28 feet away from the basket. Turns out, Thorn didn't think the advent of a 4-pointer would be outlandish at all. Rather than reflexively squash the radical idea, as you might expect from a 72-year-old NBA lifer who has worn just about every hat in the league, Thorn seemed genuinely intrigued at the notion and revealed that the 4-pointer has "come up" in league discussions. "Oh man," Thorn told Abbott, "Some of the players we have can shoot the ball 30 feet as easily as they can shoot 23, 24 feet." One of those players? Vince Carter. Thorn recalled a moment when he ran the New Jersey Nets from 2000 to 2010 as team president and general manager. As players tend to do at practice, Carter would showcase his shot-making abilities from far, far away.
Did coach Mike D'Antoni know what was going to happen when Sacre picked up his sixth foul? "Yeah …," D'Antoni said with his voice trailing off and his eyes letting reporters know he wasn't being truthful. "Not really. But it's a nice rule." "I never knew when you fouled out, you could go back in," 11-year veteran Chris Kaman said. "I never knew that was a rule. So, I had my shoes untied and I was like lying down on the bench because we had like a really long bench. There was like 30 feet of extra space."
The outcome of the Los Angeles Lakers' 119-108 win over the Cleveland Cavaliers on Wednesday will not matter in the long run — both teams were a lousy 16-32 coming into the game — but it will become a night to remember another way. It was the moment many people in the basketball world first became aware of Rule No. 3, Section I, Part A of the NBA's rulebook. "Each team shall consist of five players. No team shall be reduced to less than five players. If a player in the game receives his sixth personal foul and all substitutes have already been disqualified, said player shall remain in the game and shall be charged with a personal and team foul. A technical foul also shall be assessed against his team. All subsequent personal fouls, including offensive fouls, shall be treated similarly. All players who have six or more personal fouls and remain in the game shall be treated similarly."
New rule for this season: Players can't run to a place beyond the baseline, out of bounds, and just stand there, as more than a few teams had been doing in recent seasons. Now, the player has to return to the court immediately or his team will lose the ball. The league said upwards of 11 teams had been having players stand out of bounds, possibly to create more space in a 4-on-4 game, with Denver supposedly coming up with the strategy first.
Steve Bulpett: Sources: Competition Committee votes unanimously to return NBA Finals to 2-2-1-1-1 format. Owners' approval to come.
The NBA issued seven flopping violations in the first month of the 2012-13 season and seven in the second month. There were just three flopping violations in the third month of the season, and there have been zero flopping violations in February. "We feel that the new flopping rule is working well," NBA executive vice president of basketball operations Stu Jackson told USA TODAY Sports.
Jackson: Yes. Basketball is a simple game. Your goal is penetration, get the ball close to the basket, and there are three ways to do that. Pass, dribble and offensive rebound. The easiest one is — or should be — the pass. But the new rules allow you to throw more people at post-up players. NBA basketball is a big man's game, and in the past they protected that aspect of the game. Well, those rules went out the window and what they didn't do was consider this: If they're going to continue to allow zone defenses to work and shut down the paint, then they have to put six more seconds on the shot clock. A 30-second clock. But they're so attached to the idea of the 24-second clock that it doesn't happen.
Calling Thursday's sideline incident at Madison Square Garden that led to forward Stephen Jackson's right ankle sprain "a Mayoral mishap," Spurs coach Gregg Popovich called on the NBA to police activity along the league's sidelines and baselines. "It's maddening," Popovich said of the incident in which Jackson lost his balance after running into a waitress during the first quarter of the Spurs-Knicks game. The waitress appeared to be taking an order from New York City mayor Michael Bloomberg. "It's an accident waiting to happen."
Popovich expressed confidence the incident would spur the league to better control the sidelines during games. "After what happened, I have no doubt the league has contacted teams to make sure everybody shores up their discipline in that area," he said. "It's obvious people shouldn't be ordering beers or Cokes or hot dogs when the game is going on."
A league source told Grantland.com that NBA officials warned "about 10" players for flopping, but the league refused to release the names. "Flops have no place in our game — they either fool referees into calling undeserved fouls or fool fans into thinking the referees missed a foul call," NBA vice president of basketball operations Stu Jackson said in a statement. "Accordingly, both the Board of Governors and the competition committee felt strongly that any player who the league determines, following video review, to have committed a flop should — after a warning — be given an automatic penalty."


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41 year old man | Boston, MA, USA | Seeking women 27-39 within 50 miles
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Hello to all…and thank you for stopping by!...
Hello to all…and thank you for stopping by! Writing an original, non-cliche self description is proving to be a tough task. I mean, what guy isn't going to say he's "smart, funny and easy to be around"? Me included! Ha Ha! That said, let's give it a shot and see if I can catch your attention in 4,000 characters or less! I am a mild mannered, even tempered guy. I rarely get too high or too upset over everyday events. Instead, I tend to joke around and keep things nice and loose. If you prefer subtle, sarcastic (and maybe even witty) humor over loud and outrageous, we might be off to a good start! I actually grew up in Boston so I have many friends and family in the area. Being there for the important people in my life is a priority. I always try my best to do right by them. In return, I think they would very simply describe me as a good man. I know that's a generic term, but hopefully you know what I mean. I'm a fairly athletic guy and played sports my whole life, up to and including college. Although the glory days are over, I still enjoy an active, healthy lifestyle. As mentioned elsewhere on my profile, I have several hobbies that keep me busy. I'll spare you the details of my many fishing and mountain biking stories (for now anyways) but instead will say I don't expect you to share all of the same interests. I'm not determined to find a female version of myself, rather a sweet, happy, smart, energetic, interesting girl who can bring something new into my life. And if you do enjoy a few of the same interests, that's great, too! I think I will wrap up there for now. If you made it this far and find yourself curious, drop me a note and we can chat…… Submitted from mobile
Camping , Coffee and conversation , Cooking , Dining out , Fishing/Hunting , Movies/Videos , Music and concerts , Exploring new areas , Playing sports , Shopping/Antiques , Travel/Sightseeing , Watching sports
Baseball, Billiards / Pool, Bowling, Cycling, Football, Golf, Other types of exercise, Running, Skiing, Tennis / Racquet sports, Walking / Hiking, Weights / Machines
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Investment research for a small firm in town. I know, big surprize for a guy in Boston!
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In Panda3D, I've been learning a bit about the built-in physics engine and its collision detection features.
I'm trying to understand the DSSolid collision object, which is mentioned in a table on the Collision Solids manual page without explanation. It is tersely described in the API reference as "A collision volume or object made up of the intersection of two spheres (potentially a lens) and two half-spaces (planes)."
I basically understand that geometric description, but what is the purpose of such a shape??
Interestingly, this DSSolid is the one collision solid, other than a sphere, that can be either a "from" or an "into" solid. This suggests to me that the shape is considered to be either more commonly needed than other shapes (such as a plane or a tube or an inverse sphere), or is cheaper to test. Neither of those reasons rings true to me... a DS would be more expensive than an inverse sphere to test for collisions against, and it seems to me, less useful. So I'm wondering, what is the use case for a DSSolid?
I'm curious too how the planes are typically arranged in relation to the two spheres... but that would probably become clear given the use case for this solid.
(And what does DS stand for? Double sphere?)


text:
Mascara / Eye liner
Wave your magic wand for the best mascara reviews, and best mascara brands! Compare waterproof mascaras. Discover the best mascara for full, voluminous eye lashes or the best mascara for long, thick lashes. Get expert advice and tips of how to create a smoky eye, how to do winged eyeliner and how to use your mascara brush for optimal eyelash effect. Need tips for using liquid, gel or kohl eye liner? We've got the best tips and advice for perfect eye liner application every time!
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Mascara / Eye liner Product Reviews
Beautiful product
I just love this product. You don't need very much and it makes my hair soft and smooth straight away.
More of a corrector than concealer.
This product is available in Australia through some select cosmetic stores as well as good Ol' Target. Keep an eye out for the sales, you might catch NYX on sale like I did.
Healthy and Happy Skin
I received a sample of the Kosmea Rose Hip Oil and I was pretty impressed with the product. I have only been testing it for two and a half weeks.
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This One-bedroom Suite has two separate rooms: a bedroom with a queen-sized bed in the back and a sitting room with a futon sofa/bed in the front with. This unit is perfect for families with small children as the sitting room is a bedroom by night and space to play and relax by day.
Rates between: $110 - $190 [depending on season and number of people]


text:
Nagoya Sights and Landmarks Guide, Japan
For many people visiting Japan, Nagoya is only a bullet train stop on the way to Tokyo, Osaka, or other more touristy cities. Nagoya is indeed more of an industrial metropolis than a tourist attraction, but you don't have to be a fan of Toyota, Honda or Mitsubishi cars to enjoy a few days of wandering around Nagoya. Despite its status as a technological capital, Nagoya has played an important part in Japanese history. Some of the most important people in the history of the country hailed from Nagoya: Oda Nobunaga, Toyotomi Hideyoshi and Tokugawa Ieyasu. Many of the city's most interesting sights are deeply rooted in history, there are plenty of amazing museums and countless traditional shrines that you can visit in Nagoya. Find out more about what Nagoya has to offer in this short Nagoya Sights Guide.
Nagoya Sights - Castles and Shrines
Nagoya Castle was built in 1610 by Tokugawa Ieyasu on the site of a previously abandoned castle. The castle was destroyed during World War II, and what you can see today is a concrete replica of the original building. The most prominent features of the castle are the golden tiger-headed dolphins on the roof, symbols of the feudal lords of Japan. Atsuta Shrine hosts over 4000 historical artifacts on its grounds, among which the famous Kusanagi no mitsurugi sword. The shrine organizes over 70 festivals every year, so if you're in luck you can take part.
Nittaiji Temple has a beautiful pagoda and extensive gardens. This Nagoya Sights Guide recommends that you visit Koshoji Temple during the 1000 Lantern Festival, an impressive annual event. Toganji Temple dates back to the 16th century and has a rather beautiful statue of Buddha. Interestingly enough, the shrine hosts a temple dedicated to the Hindu goddess Saraswati. Last but not least, don't forget to visit Arako Kannon Temple, the oldest building in Nagoya, dating back to the early 8th century.
Nagoya Sights - Parks and Museums
If you're an automobile fan, visit the Toyota Commemorative Museum of Industry and Technology that offers an insight into the long history of one of the world's leading car manufacturing corporations. For more cars, this time from different eras and different countries, go to Toyota Automobile Museum.
Nagoya City Art Museum displays a few pieces by internationally known artists such as Modigliani and Utrillo, as well as works by famous Japanese artists. If you'd like to take a refreshing walk outside, spend a few hours in Meijo Park, the largest park in Nagoya, not far from Nagoya Castle.
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text:
Auction price: Register or sign-in to see quarterly averages
or visit the Wine Market Journal
Drink between: 2004 - 2009 (Add My Dates)
188 Tasting Notes
Really smooth, fruit is wrapped around a firm core. Currants and berries linger in the mouth.
Pleasure to drink well flavored mature cab
Still drinking well, but drink this one up. It's past it's peak and won't last too much longer. Paired well with grilled steak.
Elegant, mature california cab. Perhaps at its peak or just past. Drank at a friends birthday dinner. No formal notes. Everyone greatly enjoyed it.
This was still drinking very nicely. Had been stored properly since being aquired from the winery.


text:
Article Preview
Nathan's column: Plugged in and way too quiet
Published 01/18/2013, Rosemount Town Pages
Times have definitely changed. No longer do you have to power your electric car by shuffling your feet on a shag carpet. Some modern models are legitimate performance cars, with sleek bodies and the ability to get upward of 25 miles on a single charge. Truly, we are living in future times.Word count: 524
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You are here
Home » Sandwich » Meat Sandwich » Beef Sandwich » Barbecue Beef Sandwich » Barbecued Hamburger
Barbecued Hamburger
14 Nov 2009
Barbecued Beef Sandwiches! They cam be made in a jiffyand are extremely addictive. I often pack these yummy Barbecued Beef Sandwiches along for picnics and i love seeing the glee on my children's face when I pack it up for their lunch! Try this Barbecued Beef Sandwiches recipe.
|Sliced cooked roast beef
|3⁄4 Pound
|Rye bread slice/4 hamburger rolls
|Barbecue sauce/Chili sauce
|1⁄2 Cup (8 tbs)
Arrange half of beef on 4 slices bread; spread generously with barbecue sauce.
Top with remaining beef, then bread.
Wrap each sandwich in paper napkin: arrange on oven tray.
Cook at MEDIUM 3 to 4 minutes, or until heated through.
Recipe Summary
Course:Main Dish
Rate It
0 Comments
Barbecued Hamburger Recipe


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If you are using winblows 8.1 you have to advance boot and allow "unsigned drivers" and reinstall. Then all is well.
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Jennifer Lopez's Oscar Wardrobe Malfunction: 'No Chance,' Says Stylist
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Jennifer Lopez's nipple nearly stole the show at the 84th Annual Academy Awards while presenting with Cameron Diaz, 39 -- or did it?
Wearing a cleavage-baring Zuhair Murad gown, many wondered if the "American Idol" judge, 42, had an accidental wardrobe malfunction while co-presenting the Oscars for Best Costume Design and Best Makeup.
VIDEO: Jennifer Lopez barely avoids a nip slip at the Oscars
Lopez's stylist Mairel Haenn denied Lopez gave an inadvertent peep show during the telecast, telling EXTRA: "The dress fit perfectly to her every inch. There were cups built in and there's no chance that there were any, how do you say? 'slips.'"
Added Haenn: "While the dress did give the illusion of sheer-ness, joke's on everyone who wishes they saw something! If you thought that dress was hot wait until you see what's next."
PHOTOS: What all the stars wore at the 2012 Oscars
The "On the Floor" singer changed into another daring look by Zuhair Murad for the Vanity Fair Oscar party at Sunset Tower in West Hollywood, Calif. Lopez accessorized her plunging sequined gown with H Stern jewels and a Swarovski bag.
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Posted| Updated
Lawyers call for reforms to political donation laws after the ABC's Four Corners program uncovers links between Mafia figures and senior politicians.
Topics: government-and-politics, federal-government, law-crime-and-justice, political-parties, australia
Posted| Updated
Former interpreters who worked with Australia fear for the safety of their families back home in Afghanistan in the face of increasing security concerns in the region.
Topics: unrest-conflict-and-war, security-intelligence, human-interest, people, defence-and-national-security, newcastle-2300, afghanistan, australia
A report by one of Australia's main youth mental health services ReachOut.com says boosting online support networks will help reduce the strain on health system.
Topics: mental-health, youth, healthcare-facilities, australia
Posted| Updated
Retirees relying on term deposits to fund their lifestyle are feeling the pinch of record low interest rates as banks pass on the RBA's rate cut.
Topics: banking, money-and-monetary-policy, australia
Posted| Updated
Women's rights advocates call for an overhaul in the way the Government deals with domestic violence in a bid to address the rising number of women being killed.
Topics: domestic-violence, community-and-society, government-and-politics, australia
Posted| Updated
A study finds alcohol companies are increasingly using social media to link sporting success with drinking to boost sales.
Topics: sport, health, alcohol, alcohol-education
Posted| Updated
The man promoting the Government's Intergenerational Report, ABC science commentator Dr Karl Kruszelnicki, backs away from the document, describing it as "flawed".
Topics: community-and-society, work, welfare, government-and-politics, social-policy, australia
Posted| Updated
Improving education about immunisation is a better way to get people to vaccinate their children than the "draconian" move to withhold their welfare payments, experts say.
Topics: health, vaccines-and-immunity, federal-government, nsw, the-university-of-sydney-2006
Posted| Updated
Tensions between refugees and locals on the pacific island of Nauru are heightened after a series of violent attacks that have left multiple refugees injured or arrested.
Topics: law-crime-and-justice, community-and-society, immigration, refugees, nauru, pacific
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Jihadists returning from Iraq and Syria could see a resurgence in terrorism in Indonesia and become a threat to westerners, a leading terror expert warns.
Topics: terrorism, unrest-conflict-and-war, indonesia, bali, australia
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Security analysts say Muslim parents need more help to stop their children becoming radicalised over the internet, and liken the online jihadist recruitment process to grooming by paedophiles.
Topics: terrorism, unrest-conflict-and-war, federal-government, islam, australia
A study finds alcohol bought at liquor stores and drunk outside pubs or licensed venues plays a major role in causing violence across Australia.
Topics: health, drug-use, alcohol, medical-research, vic, australia
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People who drink three to five cups of coffee a day may have a lower risk of developing clogged arteries that can cause serious heart problems, a study reports.
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Australian Muslim groups condemn the use of slaves, calling it barbaric and completely out of line with Islam.
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The ethnic mix in Australia's regional areas could diversify further with the changes to immigration law that passed the Senate on Friday.
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Five US soldiers have been killed in what appears to be a friendly fire incident in southern Afghanistan.
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Pakistani security forces have cleared the Karachi airport of militants nearly 12 hours after the start of a siege that left at least 27 people dead, a paramilitary official said.
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Afghan presidential election frontrunner Abdullah Abdullah has escaped an assassination attempt after two blasts hit his campaign motorcade in Kabul, just days ahead of a hotly-contested run-off election, but six people died and 22 others were wounded.
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Senior Pakistani health officials have welcomed a move by US intelligence agencies to stop using immunisation programs as a cover for their operations.
But the move comes amid a resurgence of polio cases in Pakistan, a country once thought to be on the verge of eradicating the deadly disease.
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The man many credible Indian political experts said had no chance of being elected will now be India's prime minister.
For years, Narendra Modi was dismissed as too divisive to ever be considered as a legitimate candidate for the job of prime minister. But on Friday he declared victory after his BJP party recorded a landslide win in the country's general election.
The 63-year-old ran a slick and persuasive campaign selling himself to the country's aspirational voters as someone who can revive India's flagging economy, stamp out corruption, and place the nation on the pedestal that the world's largest democracy should be on.
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The US has offered Afghanistan aid as the country held a day of national mourning for the hundreds killed in a landslide that buried a village in the north-eastern Province of Badakhshan.
President Barack Obama offered his Afghan counterpart Hamid Karzai additional US assistance Sunday (local time) to relief efforts dealing with the landslide's aftermath.
During a phone call between the two presidents, Obama "affirmed the support of the American people as the Afghans respond to this tragedy and offered additional US assistance to the ongoing relief efforts," a White House statement said.
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Sri Lanka's navy on Friday arrested 54 asylum seekers heading by boat to Australia.
A navy spokesman says a fishing trawler was detected with the passengers - including 11 women and 13 children - off the island's north-eastern coast.
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Two bomb blasts on a train have killed a female passenger and injured nine other people, two seriously, as carriages arrived at Chennai's central railway station.
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Millions of Afghans have defied the Taliban and turned out to vote in the weekend's presidential election.
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A man dressed as a policeman shot two foreign journalists in eastern Afghanistan, killing Associated Press photographer Anja Niedringhaus and critically wounding journalist Kathy Gannon, local officials said.
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text:
Originally Posted by StoneNYC
As john pointed out I miss reads single word that caused me to miss understand... I read "I'd" for "I'll" and I thought he was going to make a split back that could attach to his current camera and was saying he would still be able to use his camera with my suggestion.
Obviously I missunderstood.
Thanks for your comments Stone, you're just trying to help. I appreciate your comments and attention to my thread.


text:
I've totally hacked together this script and I hope to get some corrections, or some insight into a much simpler version which I know is possible...
I want to loop through a named dir and check each subdir if it contains any subdirs that are X minutes old, and if so delete the old subdir. Each eligible subdir will only contain 1 symbolic link.
For this structure /var/www/flash/avmin/{$usr_id}/{$timestamp}/{->symlink}
I want to preserve /{$usr_id} but delete all /{$timestamp} if +12 hours old, and I assume this means I need to empty it before deleting it.
Because it is likely that /{$usr_id} will be created in the same server instance when $timestamp and the symlink are created, I must loop through each /{$usr_id} subdir and test conditions from there.
I will make this script run every 12 hours with Cron running as root, therefore within one 24 hour period all symlinks will be assured to be clean.
Note there may be several {$timestamp} subdirs in ../{$usr_id}, but each subdir will contain only 1 symlink and nothing else.
I sense this could be one or two lines of code without the for...in and simply using find inside avmin using (-maxdepth 2) and a time condition of X hours (or X mins) right???
for i in /var/www/flash/avmin/*
cd "$i"
for xdir in "$i"
if [ "$xdir" type d -cmin +60 ]; then
find . -maxdepth 2 -type L -cmin +60 -exec rm {} \
"$xdir" -type d -cmin +60 -exec rm {}
I saw a "similar question" which has given me an idea here


text:
Ravens Get New Start in Postseason, Will Face Off Against Steelers Saturday Night
The Baltimore Ravens are back in the playoffs, and they don't mind one bit that it took them until the final game of the regular season to get there.
2014 Top Stories of the Year
2014 Top Stories of the Year
Ravens Need a Win and Help to Reach Postseason
The Baltimore Ravens' effort to reach the postseason now includes this undesirable exercise: scoreboard watching.
Ravens' Playoff Hopes Fade in 25-13 Loss to Texans
The Baltimore Ravens want to leave behind what happened Sunday in Houston and focus on bouncing back next week.
New Video Shows Rice and Fiancee in Aftermath of Punch
A video released Friday shows Ray Rice's then-fiancee crying and kissing him while they are both handcuffed and being taken to jail by police officers after Rice punched her in a casino elevator.
Ray Rice Attends Baltimore Toys for Tots Drive
It's been almost 9 months since Ray Rice was arrested for punching his now-wife in an Atlantic City hotel, and a little over three months since his contract was terminated by the Baltimore Ravens when the full video of the assault surfaced online.
Ravens Have Favorable Path on Road to Playoffs
During a season filled with unexpected obstacles and aggravating injuries, the Baltimore Ravens appear to be finally catching a break in their effort to earn a playoff berth.
Obama: NFL 'Behind the Curve' on Rice Case
President Barack Obama says the Ray Rice domestic violence case showed that the National Football League was "behind the curve" in setting policies about athlete behavior. He says new policies now in effect will send a message that there is no place for such behavior.
Ravens Sack-Happy Dumervil Sets Sights on Playoffs
Having already placed his name in the Baltimore Ravens record book, Elvis Dumervil has turned his attention toward getting the team into the postseason.
Ravens in Playoff Hunt Despite Many Distractions
During a season filled with suspensions, injuries and painful defeats, the Baltimore Ravens have worked their way into the middle of the AFC playoff picture.


text:
Steamed, stuffed or grilled?
Greg Morris
You can buy lobster with food stamps.
Smaller backlog
Nathan Deal
Georgia has saved $20 million through changes in criminal sentencing.
Go home already?
Casey Cagle
"For every week that (state lawmakers are) able to cut off our timeline, it saves (Georgia taxpayers) approximately $100,000."
Spotlight on education cuts
Jason Carter
"Since 2009, Georgia's public schools have lost nearly 9,000 classroom teachers while the number of students has gone up."
The big peach
Kasim Reed
The annual gross domestic product of metro Atlanta is "bigger than 28 states in the union."
6 counties are lawyerless
Hugh Thompson
"Six of Georgia's counties have no lawyers at all."
Morris bill at center of debate
Nan Orrock
Florida shelled out more money for drug testing than it saved by denying welfare benefits to people who tested positive for drugs.
Claim close to the mark
Raphael Warnock
"Georgia has the fifth-highest number of uninsured people of any state in the union."
Wallets have gotten thinner
The average Georgia family makes $6,000 less than the average family did 10 years ago when inflation is factored in.
On the upswing
"(M)ore Georgians have jobs than at any other time since October 2008."
Crime down, stats show
Atlanta Police Foundation
"Crime in Atlanta is down 18 percent since 2009."
Falling out of popularity
Kimberly Nelson
"The commission form of government is definitely losing favor in the United States."
A fox-like move
Allan Levene
Says there's no language in the U.S. Constitution that prevents someone from running for Congress simultaneously in multiple states.
$756,905 and counting?
Lynn Westmoreland
"I have returned money every year since taking office."
A penny looks smart
Charlotte Nash
Finance experts estimate that paying in cash for the $2.5 billion in projects funded by the sales tax saved Gwinnett County more than $1 billion in interest payments.
Edward Lindsey
Most voters prefer zombies to the current U.S. Congress.
One small meal for mankind
Facebook posts
The very first meal on the surface of the moon was the Holy Communion.
Claim deserves to remain in your inbox
Tom Graves
"The government does not need a warrant to read your old emails."
Right on the money
Tom Price
Americans spend more than $160 billion and 6 billion hours per year complying with the tax code.
Upon further review
"State law says that once the state appraises a piece of property, they can only pay it a certain amount above appraisal."
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Rag & Bone have compiled a very classic collection of denim for spring and summer featuring a slim aesthetic. With no detailing to talk about it is the quality of fit and materials that speak volumes.
Thanks to Blackbird for the images


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Video Rental
Blockbuster Video to close remaining 300 stores, end DVD by mail service
The national chain of brick-and-mortar video rental stores that dotted the United States throughout the 1980s and 1990s will shut its remaining 300 retail stores and cease its DVD-by-mail service by early next year.
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text:
Blake scholarship helps 2
Former CCC President Dr. McKinley Martin and current CCC president Dr. Valmadge Towner congratulate Miracle Williams and Marquisha Lester. Both were recently awarded scholarships, as part of The J. Steven Blake Foundation's $100,000 endowment to CCC.
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Click to expand
What do you think? Give us your opinion. Anonymous comments allowed.
#30 - chuffberry (10/24/2013) [-]
everyone thinks i'm "creepy" and "sociopathic" because i'm obsessed with plants and genetic modification. but you know what? in my research class i have successfully grown a marijuana plant that glows green under blacklight. when smoked, the vapors also glow. i'm going to be rich from selling my GlowPot.
#31 to #30 - sacrilegious (10/24/2013) [-]
come to Washington
#32 to #31 - chuffberry (10/24/2013) [-]
already in colorado


text:
- Home
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Welcome to 2015.
AADES invites you to the Infinite Futures 2015 Conference.
The Infinite Futures 2015 Conference is scheduled for the 9th – 11th September and will focus on Educational Leadership, Innovation and Technology.
Workshops and Keynotes will be presented by International Experts, leading Principals and Heads of School Curriculum with a focus on Teaching and Learning for 2015 and beyond.
The Venue for 2015 will be the Sofitel Broadbeach (with possible additional workshop options at Griffith University Gold Coast).
Keynotes delivered by Dr Yong Zhao and Dr Steve Brown.


text:
Contract grant sponsor: French-Slovenian Egide PROTEUS project; Contract grant sponsor: Ministry of Science and Technology of Slovenia; Contract grant numbers: J1-2043 and P1-0297 (B. B. and M. K.); Contract grant sponsor: TEOMATRO; Contract grant number: ANR-10-BLAN 0207 (V. C.).
Original Article
Retracts of Products of Chordal Graphs
Article first published online: 16 MAY 2012
DOI: 10.1002/jgt.21665
© 2012 Wiley Periodicals, Inc.
Journal of Graph Theory
Volume 73, Issue 2, pages 161–180, June 2013
Additional Information
How to Cite
Brešar, B., Chalopin, J., Chepoi, V., Kovše, M., Labourel, A. and Vaxès, Y. (2013), Retracts of Products of Chordal Graphs. J. Graph Theory, 73: 161–180. doi: 10.1002/jgt.21665
Publication History
- Issue published online: 1 APR 2013
- Article first published online: 16 MAY 2012
- Manuscript Accepted: 2 APR 2012
- Manuscript Revised: 12 FEB 2012
- Manuscript Received: 5 JAN 2011
Funded by
- French-Slovenian Egide PROTEUS project
- Ministry of Science and Technology of Slovenia. Grant Numbers: J1-2043, P1-0297
- TEOMATRO. Grant Number: ANR-10-BLAN 0207
- Abstract
- Article
- References
- Cited By
- median graph;
- chordal graph;
- retract;
- Cartesian product;
- CAT(0) cubical complexes
In this article, we characterize the graphs G that are the retracts of Cartesian products of chordal graphs. We show that they are exactly the weakly modular graphs that do not contain K2, 3, the 4-wheel minus one spoke , and the k-wheels (for as induced subgraphs. We also show that these graphs G are exactly the cage-amalgamation graphs as introduced by Brešar and Tepeh Horvat (Cage-amalgamation graphs, a common generalization of chordal and median graphs, Eur J Combin 30 (2009), 1071–1081); this solves the open question raised by these authors. Finally, we prove that replacing all products of cliques of G by products of Euclidean simplices, we obtain a polyhedral cell complex which, endowed with an intrinsic Euclidean metric, is a CAT(0) space. This generalizes similar results about median graphs as retracts of hypercubes (products of edges) and median graphs as 1-skeletons of CAT(0) cubical complexes. © 2012 Wiley Periodicals, Inc. J. Graph Theory 73: 161–180, 2013


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South Korea's presidential candidate Park
'Devoted to her country': Park Geun-hye.
Posted December 20, 2012 01:30:02
'Devoted to her country': Park Geun-hye.
If you have inside knowledge of a topic in the news, contact the ABC.
This service may include material from Agence France-Presse (AFP), APTN, Reuters, AAP, CNN and the BBC World Service which is copyright and cannot be reproduced.
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Are you M. S. Fedorov?Claim your profile
Publications (5)2.48 Total impact
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ABSTRACT: The influence of a solid bottom on the "dead water" effect for gravitational and fluctuation waves (having the same dispersion law), as well as capillary waves, is calculated in a linear statement. It is found that the presence of a solid bottom aggravates the dead water effect.Technical Physics 11/2012; 57(11). DOI:10.1134/S1063784212110230 · 0.54 Impact Factor
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ABSTRACT: It is shown that the capillary analogue of the dead-water effect strongly depends on an external electrostatic field: in the presence of the field, the number of nonlinear resonance situations increases sharply. The field increases the wave amplitudes and excites both degenerate and secondary combination resonances, which are not observed without the field.Technical Physics 06/2012; 57(6). DOI:10.1134/S1063784212060126 · 0.54 Impact Factor
Article: Nonlinear Analysis of Interaction between Finite-Amplitude Capillary Waves in a Layered Inhomogeneous Liquid[Show abstract] [Hide abstract]
ABSTRACT: The nonlinear capillary wave motion in a two-layer liquid with a free surface is analytically investigated accurate to the second order of smallness in ratio of the wave amplitude to the layer thickness. The layers differ in physicochemical properties. A capillary analogue to the "dead water" effect is observed in the system in both linear and quadratic approximations. In the absence of an electric charge at the interfaces, internal nonlinear resonance interaction between capillary waves is also absent regardless of the place of their origination. When there is a charge at the interlayer boundary, capillary waves resonantly interact with each other.Technical Physics 11/2011; 56(11). DOI:10.1134/S1063784211110119 · 0.54 Impact Factor
Article: Wave motion in a gravity field on the free surface and stratification interface of a fluid with stratified inhomogeneity. Nonlinear analysis[Show abstract] [Hide abstract]
ABSTRACT: Regularities of the nonlinear gravitational wave motion in a two-layer density-stratified fluid are investigated for a finite thickness of the upper, lighter, layer. The characteristics of the nonlinear internal resonant interaction of the gravity waves generated by the free surface of the upper layer and the medium interface are considered. It is shown that in second-order calculations both degenerate (two-wave) and secondary combined (three-wave) resonant interactions may be realized.Fluid Dynamics 10/2010; 45(5):793-802. DOI:10.1134/S0015462810050121 · 0.32 Impact Factor
Article: Capillary analogue of the "dead water" effect in a stratified liquid with a charged interface[Show abstract] [Hide abstract]
ABSTRACT: In terms of a linear mathematical model of a capillary-gravitational flow in a two-layer liquid with a finite-thickness upper layer, it is shown analytically that an analogue of the dead water phenomenon exists in the domain of capillary waves, which was previously observed only in gravitational waves. This phenomenon shows up as an exponential increase in the capillary wave amplitude at the interface with the surface tension coefficient at the interface tending to zero. It is found that an external electric field displaces this phenomenon toward the range of finite surface tension coefficients.Technical Physics 07/2010; 55(7):920-928. DOI:10.1134/S1063784210070029 · 0.54 Impact Factor
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Yaroslavl State UniversityJaroslawl, Jaroslavl, Russia


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Originally written on Busted Coverage | Last updated 2/4/13
• Kate Upton wearing her Mardi Gras beads • Power company says Superdome at fault • John Harbaugh kissing Ravens owner? • AJ McCarron not beefing w/Musburger • VIDEO: Futboler knocked the f–k out • MUST-SEE: TV Azteca reporter Veronica • Candice Swanepoel. Boat. Bikini. • Jenn Sterger minus the implants! Rudy Gay Power Dunk of the Weekend  Chip Aisle At Supermarket On Super Bowl Sunday (via Reddit) Filed under: Daily Dump
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- 21Promote
Framed Art Print
You Are Who You Choose To Beby Secretly Swedish
Choose from a variety of frame styles, colors and sizes to compliment your favorite Society6 gallery, or fine art print - made ready to hang. Fine-crafted from solid woods, premium shatterproof acrylic protects the face of the art print, while an acid free dust cover on the back provides a custom finish. All framed art prints include wall hanging hardware.
My rejected Iron Giant submission, for Print Club London's Blisters exhibition.


text:
Call Ben Cantu the Energizer Bunny of Manteca municipal politics.
The Turkeys R Us effort is $10,000 short with 20 days to go until Thanksgiving.
Grace for Vets. That's the name of the program started a few years ago by Francene Escobar which gives all veterans a free express car wash at Quicki-Kleen in Manteca on Veteran's Day, Nov. 11.
Tom Wilson was amazed to see the vibrance back in the "Cow-munity" dairy mural.
Joe Pellegrino knows freedom carries an extremely high cost.
As Kristen Koehler handed in her election papers to the precinct workers, other people played goo-goo with her smiling 7-week-old son Logan in the baby carrier.
Oakland's loss is Manteca's gain.
Manteca developers have built and sold 834 homes since the start of 2007.
Job centers and not housing are in line to develop first in the proposed 1,049-acre Austin Road Business Park project.
Landon is a 3-year-old local boy who, according to his mother, Nicole, graciously gave away his Halloween candies to a good cause.
There are 24 days left until Thanksgiving and Turkeys R Us has raised only enough money so far to provide the traditional holiday meal for 1,080 struggling families in Manteca, Ripon, and Lathrop.
Manteca planners have heard a group of rural residents northwest of the city loud and clear.
Accountability is No. 1 on Chuck Carpenter's list.
Two members of the Manteca Artists Guild are taking center stage in the Council Chambers at the Civic Center.
Scenes from the Sunday "Trunk or Treat" event at Manteca High.
Page 516 of 776
Darryl Quaresma - a third generation farmer that parlayed starting work in the family dairy at the age 12 into a multi-faceted agricultural businesses - is being inducted into the Manteca Hall of Fame.
A brand new Jayco Motorhome sustained an estimated $7,000 in damages when a couple taking the vehicle on a test drive were rear ended by a late model Honda Accord.
Manteca's first single family neighborhood featuring all lots smaller than 6,000 feet under zoning changes put in place in 2012 to encourage more affordable housing is before the City Council Tuesday for final approval.
Manteca Unified School District last month recognized those selected for Educators of the Year.
Life saving memories and fleeting words of caution are often shared at the Every 15 Minutes program every year during the two-day event at Manteca High's Gus Schmiedt Field. This year was no different.
Veterans of Foreign Wars Post 1051 is asking for a $50,000 loan from the City of Manteca in order to furnish the new Manteca Veterans Center being built on Moffat Boulevard in time for the July 4 grand opening.
About 15 years, the City of Ripon entered into a long-term lease with Jack Tone Golf, LP.
Page 18 of 18
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Little Vic
Deep Concepts Media
Artist: Little Vic
Song: Bad Blood
In the near future, Long Island rhymesayer Little Vic will be unleashing a new project made up entirely of unreleased Loosies. Isn't that a contradiction in terms? The short answer is, yes. Rather than troubling... More
Posted 7 months ago
Artist: Kap Kallous
Featuring: Little Vic
Song: The Void
Last week, L.A.-by-way-of-Orlando rhymesayer Kap Kallous blessed our front page with More Grandeur, the first in a weekly series of Booth-exclusive jams he plans to unleash while touring with MURS and ¡MAYDAY!. Awarded a... More
Posted 8 months ago
Artist: Little Vic
Featuring: Kool G Rap
Song: Caked Up ft. Kool G Rap
Almost once per week, DJBooth will feature a song that looks like this: "Local Artist ft. National Heavyweight." In their attempt to get some "shine" from a popular guest feature, the... More
Posted 7 years ago
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text: Ellie Goulding Wearing See Through To Panties Dress At MTV Video Music Awards 2013 In Brooklyn New York Aug 25, 2013 Ellie Goulding Place your ad here Loading... Like the article? Please share on your social network. :) Facebook Google+ Twitter Reddit LinkedIn Pinterest You may also like ... Ellie Goulding Wearing Revealing Dress At Versace Fashion Show In Paris Ellie Goulding Wearing Shorts At Barry's Boot Camp Gym In Miami Ellie Goulding Bikini Pictures On Miami Beach


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text: On Tue, 2 Oct 2001 volodya@... wrote: > With linux, it will say something along the lines of "works with Redhat > 6.2". (take a look at many CAD packages, for example - they are _not_ very > graphics intensive). Games are even trickier. I have not bought a single > Loki game for this reason: once I upgrade to new libraries or X it will be > dead weight. And if it crashes because of incompatibility there is little > I can do to fix it. (And no, I am not going to waddle thru machine code to > fix something I paid money for). That's just not true. I still run the quake2 binary release which I first used on Redhat 5.something on Redhat 7.1. Quake3 runs better on my Redhat Frankenstein Roswell/Rawhide workstation than it did on Redhat 6.2. -d -- | Damien Miller <djm@...> \ ``E-mail attachments are the poor man's | http://www.mindrot.org / distributed filesystem'' - Dan Geer


text:
According to an aspect of the invention there is provided an apparatus for deploying a fistula device. The apparatus comprises an elongate cover member having a proximal end and a distal end, and an elongate support member within the cover member for supporting the fistula device and configured for relative movement with respect to the cover member so as to release the fistula device at a desired location.
1. An apparatus for delivering a fistula device into a wall of a patient's heart to place the fistula device in fluid communication with a heart chamber, the apparatus comprising:
an elongate cover member having a proximal end and a distal end;
an elongate support member slidably disposed within the cover member and comprising, at a distal end, a first elongate limb and a second limb shorter than the first elongate limb, the first and second limbs forming an L-shaped member;
a fistula device being supported by the elongate support member, the second limb of the elongate support member being disposed distal to the fistula device and being configured to push the fistula device proximally upon proximal movement of the elongate support member; and
a removable retaining sheath overlying at least a portion of the fistula device wherein the fistula device is transformable from a collapsed state to an expanded state when the retaining sheath is removed;
wherein the fistula device or the retaining sheath comprises a penetrating tip at a proximal end of the fistula device or retaining sheath, the penetrating tip being configured to penetrate the wall of the heart upon proximal movement of the elongate support member to facilitate passage of the fistula device therethrough; and
wherein, in use, the elongate cover member is moveable along the support member so as to release the fistula device from the delivery apparatus to permit delivery of the fistula device to a desired location in the wall of the heart.
2. An apparatus according to
3. An apparatus according to
4. An apparatus according to
5. An apparatus according to
6. An apparatus according to
7. An apparatus according to
8. An apparatus according to
9. An apparatus according to
10. An apparatus according to
The present invention concerns relates to methods and devices for placing a fistula device in fluid communication with a target vessel. The methods and devices of the invention are particularly for use in the treatment of heart disease. The term "fistula device" as used herein is to be understood to include a conduit, shunt or stent and the like.
Heart disease as referred to herein is caused by the formation of atherosclerotic lesions within coronary arteries. Atherosclerosis involves changes to the intima arterial vessel wall. Atherosclerosis is characterized by a progressive accumulation of plaque about the arterial wall and associated loss of elasticity. Artery walls consist of three layers: a layer of connective tissue, a second layer of smooth muscle cells and elastic connective tissue, and a third layer of endothelial cells. The endothelial cells are flattened and elongated and they overlap and are aligned in the direction of the blood flow. They have cell membrane surfaces which provide them with an "anti-stick" characteristic so as to avoid the build-up of substances on the inner surface of the blood vessel lumen.
Mechanical or chemical injury of the endothelial cells or damage to their non-stick surface provides sites for thrombocyte adhesion and leads to the formation of thrombi in the arterial wall. Some chemicals e.g. homocysteine and nicotine permanently open up the junctions between the endothelial cells perforating the endothelial layer. This damage allows monocytes (white blood cells) to stick to the formerly non-stick surface and pass into the intima itself, where they become active macrophages and scavenge oxidised LDL cholesterol. Aggregations of lipid-rich macrophages (known as foam cells) constitute early lesions which are often referred to as fatty streaks.
So called fatty streaks interfere with normal laminar blood flow, particularly at the site of blood vessel branches and bifurcations. They also continue to aggravate the surrounding tissue and provide sites for further thrombocyte adhesion. Over time, fatty streaks grow and connective tissue forms thereby progressively narrowing the lumen and consequently progressively restricting blood flow distally of the occlusion. Atherosclerosis may lead to myocardial infarction and angina pectoris and also contributes to the occurrences of strokes.
Currently, approximately 16 million U.S. citizens have diabetes and approximately 50% are unaware of their condition. Worldwide, approximately 110 million people suffer diabetes and recent projections suggest that this figure will have doubled in 10 years. The risk of heart disease and stroke is three to fives times greater for males with diabetes. Female diabetics are normally protected from heart disease until the menopause, however by the age of 55 they are seven times more likely to have heart disease than women without diabetes. Sixty five percent of people with diabetes also have high blood pressure and heart disease is the most common cause of death in patients with diabetes.
As a consequence of having diabetes, the blood vessel walls of a typical sufferer become thinned. If a balloon angioplasty procedure is indicated, this thinning of the walls presents two serious consequences. Firstly, since the vessel walls are thinner, they are mechanically weaker than healthy vessels and consequently they are more likely to rupture and sustain trauma. The second consequence of diabetes is that sufferers are more likely to suffer follow on post balloon angioplasty complications.
Studies by the US National Heart, Lung & Blood Institute comparing the effects of both balloon angioplasty and bypass procedures between groups of diabetic and non-diabetic and those patients with non-medication dependant diabetes indicates virtually identical long term outcomes, viz., a five year mortality rate of approximately 9%. Similar studies on medication dependant patients, i.e. those injecting insulin, indicated a five year mortality rate of 19% for post bypass surgery and 35% for post balloon angioplasty. Another interesting observation was that medication dependant diabetics are less likely to experience angina, the chest pain associated with oxygen deprivation through reduced blood flow.
On the basis of the preceding information it is evident that medication dependant diabetic patients fare considerably better when treated by bypass surgery than balloon angioplasty. Although there have been recent successes through employment of endoscopic coronary artery bypass graft (ECABG) techniques, bypass surgery typically involves sternotomy, and consequently considerable trauma, pain, and associated relatively long bed residence. Furthermore, although beating heart operations are becoming more common due to the employment of devices such as the Medtronic Endo Octopus™ stabilizer, many coronary artery bypass graft (CABG) techniques require the heart to be arrested. Amongst the possible complications encountered with CABG are the following:
Sternitis and mediastinitis, Haemolysis, Heparin rebound phenomena, Complement activation, Deterioration of the immune system, Poor appetite, Insomnia, Depression, Visual deficit, Memory deficit, Intellectual deficit, and Loss of sexual ability.
Thus, there is a need for a method by which the advantages of minimally invasive procedures and the long-term relative success rate of CABG can be combined. Such a method would be particularly suitable as a treatment for medication dependant diabetics.
The function of the methods and devices of the invention is to re-establish and maintain an adequate supply of oxygenated blood to heart tissue in areas formerly starved of oxygen. These regions of oxygen starved tissue are typically distal of an atherosclerotic lesion. The devices and methods described herein source oxygenated blood from a chamber of the heart, for example from the left ventricle (LV) and redirect this blood via a connecting conduit (shunt) to a portion of the left anterior descending coronary artery (LAD) or circumflex artery lying distal of the lesion.
U.S. Pat. No. 6,123,682 discloses a closed chest coronary bypass implant (conduit) for forming a channel directly from the left ventricle of the heart into a coronary artery distal to an obstruction or narrowing. In various embodiments disclosed, the implant can be used in an open-chest procedure, closed-chest procedure or alternatively, by catheter access to the coronary arterial vasculature and chambers of the heart via two incision sites, one in the groin and one in the right superior-anterior chest. The implant disclosed can be an L-shaped or T-shaped hollow stent which may be rigid or may have varying flexibilities. The device disclosed includes a capacitance pressure reservoir for storing pressurized blood during systole, for delivery to the heart muscles during diastole when pressures are reduced. In the catheter-controlled embodiment, a channel is ablated through both the chambers of the heart and the coronary artery wall using an ablating tip.
International Patent Specification No. WO 00/21461 discloses methods and devices for delivering a conduit into a heart wall to place a coronary vessel in communication with a heart chamber and for removing tissue from the vessel or heart wall to facilitate such communication.
WO 00/6607 discloses methods and devices for placing a conduit in fluid communication with a target vessel. The device includes a handle, a shaft assembly and a conduit having a vessel coupling.
WO 00/6609 also discloses methods and devices for forming a fistula device to place a target vessel in fluid communication with a source of blood, such as the aorta or a heart chamber.
The present invention seeks to alleviate the disadvantages of the known devices by providing an improved method and device for placing a conduit in fluid communication with a target vessel.
Accordingly, the present invention provides a delivery apparatus for delivering a fistula device into a wall of a patient's heart to place the fistula device in communication with a heart chamber, the apparatus comprising an elongate cover member having a proximal end and a distal end; an elongate support member provided inside the elongate cover member with the elongate cover member and the elongate support member being moveable with respect to each other; and a fistula device supported by the support member, wherein, in use, the elongate cover member is pulled in a proximal direction to allow the fistula device to be released from the delivery apparatus and to deliver the fistula device at a desired location in the wall of the heart.
Preferably, the delivery apparatus comprises a retaining sheath overlying at least a portion of the fistula device, the sheath being moveable to expose the portion of the fistula device covered by the sheath.
Conveniently, the fistula device comprises a stent which is moveable between a collapsed condition when covered by the retaining sheath and an expanded condition when the sheath is removed.
Preferably, the delivery apparatus includes means for urging the fistula device through the wall of the heart.
Conveniently, the elongate support member is substantially straight over its length. The elongate support member conveniently includes a short limb and a long limb defining a generally L-shaped member at the distal end of the elongate support member. The short limb of the generally L-shaped member abuts the fistula device at the distal end of the fistula device.
Ideally, the means for urging the fistula device through the wall of the heart comprises the short limb of the L-shaped member.
Conveniently, the delivery apparatus also includes an inner rod connected to the short limb of the L-shaped member, the inner rod extending into the fistula device for at least a portion of its length.
Advantageously, the fistula device includes a penetrating tip for penetrating through the wall of the heart- and facilitating passage of the conduit into and through the heart wall.
Conveniently, the elongate cover member comprises an outer tube which covers the elongate support member and the latter is in the form of an inner tube. The fistula device is moveable between a storage mode in which the fistula device is contained inside the delivery apparatus, with the fistula device lying alongside the elongate cover member at one elongate side of the fistula device and with the elongate support member at the other elongate side of fistula device; and a delivery mode in which the elongate cover member is moved in a proximal direction to release the conduit from the delivery apparatus.
Some of the prior art devices require loading of a delivery device by firstly using a puncture wire to perforate the artery wall and myocardium and then pushing the delivery system containing the fistula device e.g. shunt, stent or conduit over the puncture wire and into position. Other prior art devices have a penetrating tip to facilitate penetration of the heart wall.
However, the delivery apparatus of the present invention has the advantage that the apparatus is loaded by pulling it into position i.e. the conduit is released from the delivery apparatus by pulling the elongate cover member in a proximal direction. Delivery by using this pulling action allows for greater control of the loading procedure since the forces required to puncture the myocardium and artery wall are most easily generated in this way. This loading method also has the advantage of naturally directing the resulting blood flow from the underlying heart chamber distally, and lessens the possibility of a jet of blood impinging directly onto the artery wall. The delivery apparatus of the invention has the further advantage that it is steerable and therefore allows the fistula device to be torqued, thereby facilitating ease of positioning within the coronary artery.
The present invention will hereinafter be described in conjunction with the following drawings figures, wherein like numerals denote like elements, and
The following detailed description of the invention is merely exemplary in nature and is not intended to limit the invention or the application and uses of the invention. Furthermore, there is no intention to be bound by any theory presented in the preceding background of the invention or the following detailed description of the invention.
Referring to
The method of delivery of a fistula device using the delivery apparatus 1 will now be described with reference to
As shown in
The entire delivery apparatus 1 is then pulled proximally by the surgeon, so that the short limb 33 of the L-shaped member 32 urges the fistula device 4 through the coronary artery wall and the myocardium 70 and into the underlying heart chamber as shown in
In the next step, shown in
The penetrating tip 6 of the fistula device 4 is anchored in the myocardium by anchoring means so as to prevent it from being pulled out of the myocardium while the sheath is being removed. One embodiment of such anchoring means is described hereinbelow with reference to
Referring to
In a second embodiment (not shown in the drawings), the delivery apparatus may include a small reservoir for the collection and storage of oxygenated blood during systole (i.e. the period of contraction of the heart during each cardiac cycle) from the underlying chamber and the delivery of this blood to the coronary artery during diastole (i.e. the period of relaxation of the heart during each cardiac cycle). This avoids any problems arising from the provision of blood to the artery during the systolic phase and not during the diastolic phase. This is achieved by ensuring that blood is available at all times of the heart cycle and most importantly during the diastolic phase as naturally happens in the normal coronary vasculature. During the systolic phase, high pressure in the ventricle causes blood to flow into the coronary artery and the blood reservoir. Because of heart muscle contraction, the coronary arteries may have collapsed, thus reducing the available volume for oxygenated blood flow. This is where the reservoir is of use since it stores some excess blood from the ventricle during systole. The wall of its membrane possesses a natural elasticity, since it will most likely be manufactured from a durable elastomer that is capable of repeatedly contracting once the pressure in the ventricle drops (during diastole). This forces the blood out of the reservoir and into the coronary artery making up any shortfall in the supply during this part of the cycle. A non-return valve ensures that no blood returns back into the chamber from where it originally emanated.
The apparatus of the first and second embodiments described above are the preferred forms of the apparatus of the invention.
Referring now to
As shown in
Referring now to
Referring initially to
Referring now to
In an alternative embodiment to that shown in
Each of the following 3 alternative methods of deployment of the delivery apparatus are further possible alternative methods of deploying the Ventricular fistula device and address the issue of anchoring the tip of the fistula device in the myocardium so that the fistula device is not pulled out of the heart wall when the sheath is removed.
In some instances, a lesion must actually be crossed to deliver the device to the intended site. Depending upon the severity of the lesion, this will present varying degrees of difficulty. In order to avoid this, an alternative embodiment of the delivery apparatus, shown in
The change in the normal velocity profile is expressed mathematically as Volumetric flow rate Q=∫VdA. Placing the fistula device proximal to the lesion attempts to change the distribution of V with respect to radial distance from centre of artery and thereby get a high flow rate down the artery.
In an alternative embodiment shown in
As shown in
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The overview of metabolism Associate professor Shi-Jie Liu,Ph D. Department of clinical pharmacology, Xinqiao hospital, TMMU. An open system:Exchange mass and energy ΔS surrounding+ΔS system>0, biology capture negative entropy from surrounding Metabolism: The total of all chemical reactions in an organism Purposes: To acquire free energy To acquire reduction potential To synthesize the structure unit molecules The design of metabolism • The amount of reactions in metabolism is large, but the kind is small and the mechanisms are similar • A lot of molecules are involved in metabolism, but only a few of molecules play key roles in metabolism • The different metabolic pathways are controlled by similar mechanism The design of biochemical reactions • Impossibilities of thermodynamics: Almost biochemical reactions do not spontaneously process without extra free energy • Impossibilities of kinetics: Almost biochemical reactions do not actually occur without catalysis of enzymes • Enzymes: Control almost biochemical reactions. The role of enzymes in metabolism • Enzymes can't change the direct of reactions, but decrease active enery of reactions • Pacemaker enzyme(or regulate enzyme): An enyme that catalyzes a committed step in a biochemical pathway • Anabolism: Large complex molecules are synthesized from smaller molecules. • Catabolism: Large complex molecules are degraded into smaller and simpler products • These two pathways are completely difference The intermediate molecules • ATP: the energy currency • NADH/NADPH: the carrier of electrons • Coenzyme A: the carrier of acyl • Biotin: the carrier of CO2 • Isopentenyl pyrophosphate: the carrier of five-carbon structural units. ATP+H2O=ADP+Pi ΔGº'=-7.3 kJ/mol ATP+H2O=AMP+PPi ΔGº'=-32.2 kJ/mol PPi+ H2O=2Pi ΔGº'=-32.2 kJ/mol Phosphate group transfer potential: the tendency of a phosphorylated molecule to undergo hydrolysis In cell: 500=[ATP]/[ADP][Pi] The compartmentation of metabolism in eukaryote cell • Glycolysis: all in cytoplasm • Gluconeogenesis: Pyruvate carboxylase in mitochondria • Citric acid cycle: all in mitochondria • Fatty acid breakdown: all in mitochondrial matrix • Fatty acid synthesis: all in cytoplasm • Stage 1: The major nutrient molecules are degraded to building block molecules • Stage 2:The building block molecules are converted to a small number of simpler molecule,such as acetyl- CoA • Stage3: The acetyl group of acetyl-CoA enters the citric acid cycle and is completely oxidized. The regulation of metabolism • The amount of enzyme in metabolism is controlled • The activity of enzyme is controlled by: – Allosteric regulation – Covalent modification – Compartmentation • The anabolic and catabolic pathways are completely difference • Many reactions are controlled by state of energy. Summary • The system of living organism • Metabolism, anabolic and catabolic pathway • The purposes of metabolism • The design of reactions in thermodynamics and kinetics • Three stages of energy captured from food • The regulation of metabolism Key words • System of living organism • Metabolism; Anabolism; Catabolism • Genetic control, Allosteric regulation, Covalent modification, Compartmentation • ATP; NADH/NADPH; Biotin; Coenzyme CoA; Actyl-CoA; Isopentenyl pyrophosphate Thanks
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Comprehensive, industry-specific ERP solution from Microsoft.
Customer relationship management for sales, marketing, customer services and social listening.
Better overview, better decisions, better business - with InfoSuite Business Intelligence.
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Professed in the company a comprehensive, systematic approach to business objectives ensures our customers in receive of efficient and satisfying the requirements solution that will provide competitive advantages and open up new opportunities for further business development. More details…
The next major release of Microsoft Dynamics AX is code named 'Rainier'. It is a new cloud optimized platform for deployments in private and public cloud as well as on-premises. It…
Nucleus Research has updated matrix of global players CRM market. Microsoft Dynamics CRM is the leader in terms of usability and functionality.