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ride'n 2 live
Joined: Sep 2004
Location: the garage
Oddometer: 2,868
Mark, thanks, a job well done on site picking. All who i met & did not meet, thank you as well. If i can remember how to post pics i will, some pretty sick scenery up there THANKS AGAIN!
Content, NEVER!
Gnarly Adventurer
Joined: Apr 2007
Location: my wife's handbag
Oddometer: 458
Santa Barbara to WMRS
Gillafunk, I'm gonna hi-jack your thread with our ride report.
Bob (big guy, bright green jacket on a V-Strom) & I left Santa Barbara Saturday morning headed to Bishop.
My wife saying good bye:
Hittin' the road
Hauled arse to Mojave where we grabbed gas & food. While stopped we noticed that Bob's chain guard threw a bolt. Easy fix, but just another reason why not to ride a bike with a chain!! Right Bob?
Take a good look at the rear tire, you will be seeing more of this later.
We got to the campground just north of Bishop around 2:30pm. We needed to be at Red's Meadows for dinner at 5:30 so we set up camp quickly.
We were probably the last group to show up at camp. Here's some pic's of camp.
Our camp:
More pics of the valley where the campground was located. Right on the river, what an awesome area:
Looking down into the valley at the campground in the distance:
After setting up camp we headed to Mammoth to see Devil's Post Pile and then to Red's Meadow for dinner. I ski Mammoth between 20 & 30 days a year, this is the fist time I've been here when the road up to the national park was open. This was a real treat for me to see after being so close so many times but never able to drop down into the valley due to impassable conditions.
We had to hike about 15 minutes to Devil's Post Pile from the parking area. A few pic's walking up to the monument:
Devil's Post Pile, easy to see how it gets the name:
We made it to Red's Meadow and had a great dinner, sorry no picks.
After dinner, had a great ride thru Mammoth and into the valley back to camp.
Bob and I had a few cocktails and laughs. Here he is thanking my wife for the Appletini's that she mixed up for us. I now it sounds gay, but nearly straight vodka with green apple flavor, got the job done.
Sunday morning, we shook off the fog from the night before and headed to Big Pine to start the WMRS ride. As we left camp, I told Bob that I thought if we turned right out of camp onto Benton Crossing Road (instead of left), we should end up back at Hwy 395. Well, not exactly! The road led us thru the mountains for about 30 miles, where it dropped us onto Hwy 6, about 35 miles north of Bishop. Oh well, had a great ride with great views and very little traffic.
Here's some sheep we encountered along the way. I would find that sheep would be a popular topic around camp, don't ask me I'm new to this deal. I come from a dessert racing background where you would typically not sit around a camp fire with grown men, discussing their interests in sheep, whatever!
We blew thru Bishop and headed to Big Pine for some breakfast before heading up to WMRS.
Hwy 168 heading up to Bristlecone Pine Forest was probably the best high speed, twisty road I have ever been on. WOW, what a ride. Worth going just for that 13 mile stretch!
Pic's of White Mountain Road headed up to the Research Station:
Check out the road behind Bob:
Made it up to WMRS and had a look around. We debated on whether to hike to the peak. Concerned we didn't have enough time left in the day, since the hike is 3 hours up & 2 hours down. We opted to skip the hike. Later in the day we will be very glad about our decision.
WMRS pic's:
Veiws from the station:
More sheep, go figure:
Pic's from the way back down:
Okay, enough of the scenery pic's.
So, remember the picture of the V-Strom rear tire I told you to keep in mind earlier, this is where that comes back up. About 7 miles into the decent from WMRS on the dirt road, a rock punctures the tire. No big deal, we have plenty of plugs, air pump, and plenty of time. Well, it was not to be so simple. The puncture occurred around 1:30 and we made it back to camp after 9 that night.
A few pic's of the repairs:
One of the many attempts (between 10 & 15) of the plug to stick. Because of the type of tear, the plugs would not seal. Not the best tire of choice, but didn't know the gravel road would actually be a sharp, jagged, loose shale rock road.
Effects of a plug after riding on it for a while:
Bob finally got one of the plugs to seal while I went to Bishop to try to find more suppliers for better repair attempts. By the time I got back he was sitting at 395 & 168 with a successful plug. We limped to Bishop for dinner & then to camp.
For some reason people post pic's of food, here's ours:
I don't have any pic's from camp that night, but boy was the guy (Mik) ripped. He was the one that questioned why I rode on the pegs on the dirt road. Nice guy and a good time.
So we got up Monday morning, packed and needed to focus our attention on what to do about the rear tire, since it would not make it back to Santa Barbara.
We went to KTM in Mammoth to see if they could help with the tire, at least get it off the rim so we could patch it.
Let me start this section off with our phone call to KTM:
Bob: What time do you guys open?
KTM parts guy: Uh, we're open!
Bob: Can you tell me where your located?
KTM parts guy: We're in the Industrial Park
Bob: Can you tell me where that is, I'm not familiar with Mammoth.
KTM parts guy: Uh, take the first left into town.
Bob: Okay, from which direction, what street?
KTM parts guy: Well, uh, you know, over by the industrial park
Scary huh. We kind of had a feeling of what we were in store for.
We get over to KTM & we talk with the owner. Bob gives him the story of the tire and our situation with being nearly stranded. The guy says that due to insurance reasons he can't touch the rim and can't help. Keep in mind that sitting in his show room are 3 adv style bikes that have the same type of rim. So if I bought a bike from him he could not fix the tire that was on the bike that he sold me?
So when we saw that we were getting no where fast with KTM, we ask to buy some tire irons and do it ourselves. KTM parts guy: Um, well we don't have any of those. WHAT, AN OFF-ROAD MOTORCYCLE SHOP WITH NO TIRE IRONS, un f'n believable!!
We went to the Chevron station and Carl (the main guy) just so happened to be on his DS bike, which had tire irons. He let us borrow them so we could take the tire off and try and patch it. Awesome guy, we extend a lot of gratitude to him just for helping us with solutions, that's all we needed. It was a pain to get the tire off by hand since it is a stiff walled street tire, but we did it.
We took the tire over to Good Year and they put an internal patch on it. We got it back on the rim and geared back up and headed back to Santa Barbara. By this time it was 3pm.
We hit 395 towards Mojave to gas up. Just outside of Lone Pine I felt something slip out of my pocket. I see in my mirror a silver shiny object skidding down the freeway behind me. Suddenly I realize it was my PDA phone. I turn around and am lucky to find it. I knew it would be trashed but I at least wanted the memory chip out of it for stored info. The phone doesn't look to bad, can't believe it wasn't hit by the 3 semi's behind me and considering it hit the pavement at 75mph. BTW, I put a new battery in it this morning and it is as good as new.
We got to Mojave for gas and food. We found that the patch in the rear tire seemed to be holding, however, the tire tread was breaking down, likely from all of the abuse the day before. The steel belts were showing thru and we had a long way to go.
We have a friend that lives in Santa Clarita, about 70 miles from Mojave. It took us over 2 hours to get there, doing only 50mph, a little scary on the freeway, but the tire held.
Along the way we had a great sunset. The sky was filled with smoke throughout the entire Mojave valley, creating an awesome red sky. This is the Zaca fire which started on July 4th in Santa Barbara. It's amazing how far it has spread, over 70,000 acres burned to date.
We made it to our friend John's house in Santa Clarita to formulate another plan for the next 80 miles back to S.B. He let Bob borrow his new Corvette to drive back home and deal with his tire later. bob was extremely greatfull for John's offer. I rode back to S.B. and made it in around 11:30pm last night...........long day!
Here's a pic of the tire at the end, not much left.
A pic of the original puncture:
After all of the issues we encountered with the tire, we had an awesome time, saw some beautiful scenery and met some good people........wouldn't have changed a thing about the trip.
Thanks to Stonewall & all who helped put the event on, we hope to see you all at another event.
sbbillder screwed with this post 08-07-2007 at 08:18 PM Reason: wrong business name
ahead of his flamin star
Joined: Dec 2003
Location: Santa Maria, Ca
Oddometer: 3,321
Glad to hear you both made it back ok.
Walt '05 R1200GS Carrizo Plain website.
2015 Fitness Goal: hike 1200 miles. Only 402 more to go!
Viel Spass, Vato!
Joined: Nov 2003
Location: San Antonio, Tx
Oddometer: 28,883
Lovely pics of a very beautiful area.
Gracie's Gold
Born Again Pagan
Joined: Jul 2004
Location: 67km east of la república socialista de Kalifornia
Oddometer: 1,460
Some pics
This years dinner entertainment..
ADVRider fuel
ADVRider fuel, too
Hurty, or some guy on Hurty's bike heading out
Heading up
Getting close
Made it
Headed down
The Ice Age Made Me The Man That I Am Today
40MileDesertRat screwed with this post 08-07-2007 at 08:16 PM
Gnarly Adventurer
Joined: Apr 2007
Location: my wife's handbag
Oddometer: 458
Thanks for the words. Wish we had known someone else was going up from our area, Santa Maria is right up the road from me. I think I saw you guys, at least the V-Strom sticks in my mind.
Let me know if you guys are interested in going on any local rides. We ride quite a bit and always looking for good company.
Hope you guys had a good weekend.
Beastly Adventurer
Joined: May 2003
Location: Somewhere
Oddometer: 3,082
while I was working, you goof balls were out having a great time....
that just hurts!
Studly Adventurer
Joined: Feb 2004
Location: Escondido Ca .USA
Oddometer: 968
WMRS Tire Report II
My buddy Dean had a flat Wed nite on 395 near Kramer Junction. We got some air back in it but the tire delamented and was like a egg. He had to ride the shoulder back to Victerville in the dark.Thur morn we got a new one at the Suzook shop and we were good to go.
Studly Adventurer
Joined: Feb 2004
Location: Escondido Ca .USA
Oddometer: 968
WMRS Pics.
Here are some ramdom shots. Man I had a good time!
The GS Ride.
The Fri afternoon ride.
From this
To This
Bald Mtn. Lookout
The ride home.
See Ya Later
Joined: Jun 2007
Location: NBC lot in Woodland Hills CA. Muntz Raceway, Simi
Oddometer: 25
Thanks to Stonewall and family
I had a great time and met some great folks. The views were spectacular! And my boots are still soaking wet!
Glad to hear everyone made it home in 1 piece...
Spineless Adventurer
Joined: Jul 2005
Location: Near Vana
Oddometer: 5,947
"The female ass is a mysterious creature." Sir David Attenborough
Zen Slug's Rides
Join the ADV TooL PooL!
Studly Adventurer
Joined: Jun 2006
Location: WestSacCA
Oddometer: 777
Had a great time at WMRS III, met alot of amazing people, saw some great country, and made it home in one piece, what more could you want from a weekend??
A special thanks to Stonewall for putting this together
I may get older but I refuse to grow up
"Stay smart. Don't put your stupid hat on at this point in time... " Gov. Pat McCrory
ahead of his flamin star
Joined: Dec 2003
Location: Santa Maria, Ca
Oddometer: 3,321
Walt '05 R1200GS Carrizo Plain website.
2015 Fitness Goal: hike 1200 miles. Only 402 more to go!
Loving it!
Joined: Sep 2006
Location: Digging in with McClaw's Div waiting for Jackson
Oddometer: 3,734
I use profanities
Joined: Jan 2005
Location: Penngrove, California (Sonoma County)
Oddometer: 4,179
Hey...anyone seen where the guys who were taking video of the water crossing at the base of Silver Canyon posted their video and posts? Im looking to see documentation of me speeding my GSA throug a stream to a quick choking hault!
oh...I should have a detailed repair cost estimate tommorw to share with you all. However, the first thing Michael said was "Why dont you have a snorkel on this thing if your gonna be doing water crossings THAT deep?
EVERYTHING I need to know I learned from Porn
2011 Gear-Up; "سميرة" (Samira)
2013 DR800; "The Dirty-Hooker Too"
2007 FJR1300; "Sally Jupiter"
2003 1150GSA; the 2 Wheeled Submarine
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Posts Tagged 'Obama'
Russian Hackers Reading Obama's Personal E-mailsSunday, April 26th, 2015
Russian hackers who invaded President Barack Obama's personal e-mail last year were far more successful than previously reported, The New York Times reported Sunday.
No classified information was hacked, but the invaders were able to read President Obama's personal correspondence with diplomats and e-mails concerning policy and legislation.
The hackers penetrated the State Dept.'s unclassified e-mail system and Obama's unclassified account.
The invasion, although it did not reach classified information, could be extremely embarrassing for the Obama administration. It is assumed that the hackers were working with or for the Kremlin.
"This has been one of the most sophisticated actors we've seen," one senior American official told the newspaper. "It's the Russian angle to this that's particularly worrisome," another senior official said.
The president reportedly writes on personal emails about subjects ranging from his golfing to efforts by Republican Congressmen to hamper his proposed deal with Iran over its nuclear program.
If the mails reach the office of Russian President Vladimir Putin, he might learn secrets about how President Obama missed an easy putt on the 17th hole, or perhaps what he really thinks about Sen. Bob Corker, who initiated the bill that would require Obama to submit to Congress for review any final deal with Iran.
If President Obama wrote to a diplomat about what he really thinks about Putin, the Russian president will read some unflattering remarks, assuming Obama does not see him as a "warm friend."
And what does Obama write about Prime Minister Binyamin Netanyahu in his emails? He also is probably not described as a "warm friend."
The White House is not revealing the content of the material that was hacked in order not to hint to the Russians how much investigators know about the computer invasion.
And perhaps the Russian hackers now know what many Americans would like to know about Hillary Clinton's use of her personal account for State Dept. correspondence.
President Obama not only knew about Clinton's routine of using her personal account for government business but also wrote to her on her private account, "email@example.com."
After Obama told CBS News that it was "through news reports" that he'd learned that Clinton was using her personal account, White House Press Secretary Josh Earnest said, "The president — as I think many people expected — did over the course of his first several years in office trade emails with the secretary of state."
The Republican National Committee accused Obama of misleading the American public by having said he knew of Clinton's practice "through news reports."
Any questions about Obama's correspondence with Clinton can be directed to the Russian hackers.
President Rivlin's Independence Day Message Thanks Jews in the DiasporaTuesday, April 21st, 2015
President Reuven Rivlin's Yom Ha'Atzmaut message to Jews in the Diaspora thanked them for contribution to the Jewish state but did not even whisper a hint that they should make Aliyah and come home.
Israel and Jews around the world celebrate Israel's Independence Day Wednesday night and Thursday, one day before the usual date of the 5th of Iyar in order to avoid desecration of the eve of the Sabbath and celebrating through Friday evening.
This also is President Rivlin's first year in office, and he did not even tiptoe the issue of Aliyah. He simply ignored it.
Suggesting Jews in the Diaspora to move to Israel usually is an itchy subject. Prime Minister Binyamin Netanyahu angered some French leaders and especially the French government last year when he flatly stated after a terrorist attack on Jews at a kosher deli in Paris, "The State of Israel is not just the place to which you turn in prayer. The State of Israel is also your home."
David Ben-Gurion, when he was Prime Minister in 1961, hit a brick wall in Baltimore when he told rags-to-riches millionaire Jacob Blaustein he expected several thousand American Jews to move to Israel every month.
Blaustein told Ben-Gurion, "American is our home."
President Rivlin played it safe and patted American Jews on the back without ruffling any feathers.
He told them in the video that can be seen below:
Israel will forever be indebted to our friends and supporters abroad. Those who have contributed and continue to contribute to charities and foundations, those who have volunteered in the Israel Defense Forces even at times of war, those who stand up for Israel in the media – you are all part of the Israeli family, and should take joy and pride in Israel's independence celebrations….
Together, we can work to ensure that Israel fulfills its promise of a Jewish and democratic country, with equality and freedoms for all its citizens.
I wish you all Chag Atzmaut Samayach and may we all enjoy a successful and prosperous Israel.
Americans, especially Jews, love to hear about "equality and freedom" in Israel. It makes them feel proud to be Jewish Americans – and not American Jews – so the non-Jewish community can huff and puff that the United States of America is the model for Israel.
America, the country where church is church and state is state and never the twain shall meet.
America, the melting pot.
America, where the assimilation rate among Jews is 70 percent.
If the Obama administration has not convinced American Jews to move to Israel, maybe Hillary Clinton can succeed.
Khamenei Mocks Obama Officials' Silly Bluffs'Monday, April 20th, 2015
Ayatollah Seyed Khamenei mocked the Obama administration for "silly bluffing" and charged the United States with creating a "myth" of nuclear weapons to portray Iran as a threat.
The most "vital threat" to the Middle East really is the United States and the "Zionist regime," declared Iran's highest authority.
While he belittled the White House, Iran's senior military commander insisted that there is no way that Iran ever will agree to inspections of its military facilities.
Open inspection of Iran's nuclear facilities is one the biggest holes in the framework agreement with Iran that was approved by President Barack Obama. He stated after the P5+1 concluded the framework deal with Iran:
Iran has also agreed to the most robust and intrusive inspections and transparency regime ever negotiated for any nuclear program in history. So this deal is not based on trust, it's based on unprecedented verification.
Iran's Revolutionary Guards deputy-commander Gen. Hossein Salami said on Sunday:
We would not allow such demands [for inspections] even in their dreams to be realized; military centers should be protected against any such violations; a foreign inspector in our garrison would mean occupation of our soil, since it has all our defensive secrets. This would mean national humiliation as well.
So much for "robust and intrusive inspections."
The word "humiliation" is a key, a term that you will not find in any agreement between the West and Iran because it is something that the United States simply does not understand.
The White House conveniently shoves away Iranian hate language, such as "Death to America" as nothing more than hot air for the "domestic audience."
The Obama administration psychologists figure that if they let Iran spout off, it will please the folks back home while the Islamic regime secretly plays by Western rules and agrees to what it signs.
"Humiliation" is one of the biggest – if not the biggest – obstacle to any agreement with any Islamic country. The obvious example is that accepting Israel as a country is humiliation.
Iran has to sell to its citizens a deal that humiliates the United States. The more Iran's leaders scream "no inspections" and "no sanctions," the harder it will be for it to lie to the "domestic audience."
Khomeini's latest rant rejects the idea that Iran even dreams of having nuclear weapons. Instead, he charged that "the most vital threat posed to the world and the region is the US and the Zionist regime which meddle and kill people anywhere they deem to be necessary without any control or commitment to conscience or religious principles."
Khamenei's belittling of the Obama administration works to the favor of Republicans and makes some Democratic Congressmen feel a bit silly, to use Khamenei's word, by backing the president.
Republican U.S. Senator Bob Corker, who helped initiate and draft the bill to give Congress the right to review any final deal with Iran, told CNN on Sunday that lifting sanctions will be phased, a concept that Iran has totally rejected before the ink was dry on the April 2 temporary agreement.
GOP presidential candidate Sen. Marco Rubio warned on Face the Nation that the United States might have to take military action if Iran does not toe the line.
"We don't want that to happen, but risk of a nuclear Iran is so great that option must be on the table," Rubio said.
Obama's Creativity: Signing Bonus Substituting for Sanctions LiftingSunday, April 19th, 2015
Are Americans going to let the administration off the hook for pretending a significant infusion of money as a reward for signing whatever deal the western allies present to Iran is different from the immediate lifting of sanctions?
You see, the western negotiators are stuck.
That's because the Ayatollah and his team have begun demanding that, as a reward for coming to any agreement with the great Satan (the United States) and its buddies regarding its own nuclear program, the economic sanctions imposed upon it for violating years of United Nations resolutions against it immediately be lifted.
But the U.S., at least, began this latest round of negotiations by promising its people that those economic sanctions connected to Iran's nuclear program will only be lifted when Iran has met its obligations under the new deal, not simply when it promises to do so.
Iran is driving a hard bargain. It is insisting that those negotiating with it actually respect its demands, even if Iran has not, and continues to give every reason to believe it will not, respect the terms demanded by others.
So what is an administration, hell-bent on achieving a foreign policy success at any cost, going to do?
Apparently the answer to that question is "be creative." And that is just what U.S. President Barack Obama promised to be, in an effort to give Iran what it says it needs and still allow the American negotiating team and its supporters to insist that the sanctions on Iran will not be lifted immediately.
Instead, Obama suggested at a news conference on Friday, April 17, that it would be willing to provide a "good will gesture" of significant economic relief upon the signing of the nuclear agreement. Think of it as a signing bonus given to desired major league players just for agreeing to come join the team, without ever having to even pick up the ball to play.
And at the same time the administration can continue to state – mostly with a straight face as they're already pretty adept at this kind of thing – that there will only be a phased-in relief to sanctions, pegged to compliance with the signed agreement.
In other words, as described in Friday's Wall Street Journal:
The Obama administration estimates Iran has between $100 billion and $140 billion of its oil revenue frozen in offshore accounts as a result of sanctions. U.S. officials said they expect Tehran to gain access to these funds in phases as part of a final deal. Iran could receive somewhere between $30 billion and $50 billion upon signing the agreement, said congressional officials briefed by the administration.
The president presented this word game as something that is intended to dupe Iranians while allowing their leadership to save face, "get to our main concerns while allowing the other side to make a presentation to their body politic that is more acceptable," of course the Iranians can make the same exact claim to their constituents.
The difference, of course, is that all the West gets is, maybe, a signed deal with the Iranians, while the Ayatollah and the Iranian political leaders gain enormous and immediate financial relief for their people.
Now you'll be hearing lots of emphasis on the importance of sanctions being able to "snapback" if there is any backsliding by Iran on the nuclear agreement. But given the chance that Iran will get, free and clear, large infusions of money simply for signing the agreement, the already heavily criticized as unworkable snapback concept becomes less significant.
ISIS Expands To Afghanistan and Kills 35 in Suicide AttackSaturday, April 18th, 2015
The Islamic State (ISIS) has claimed its first "success" in Afghanistan by staging a suicide attack on Saturday that killed at least 35 people and wounded 125 others.
The motorcycle bombing at a bank branch was aimed at soldiers and civilians who were lined up to receive their monthly salaries.
Afghanistan is trying to keep the Taliban terror organization under control following the US Army invasion of the country after the 9/11 terrorist attacks. The United States' mission, later joined by NATO, was to destroy Al Qaeda and remove Taliban from power.
President Barack Obama declared "victory" over Al Qaeda with the assassination of its leader Osama bin Laden in 2011.
The victory was illusory. Despite all the headlines focusing on the Islamic State, Al Qaeda also has gained large swaths of territory in Syria and Yemen.
The Islamic State's expansion into Afghanistan, following attacks in Libya and Egypt, follows a warning to the Obama administration last month by President Ashraf Ghani:
If we don't stand on the same line united, these people are going to destroy us.
A White House statement said:
This visit…was an opportunity to review the remarkable strategic, political and economic achievements of this partnership and the successful completion of the security transition in Afghanistan.
He has said the same thing about Yemen and Iraq.
Who's next?
Obama Saves 'Never Again' but Steers Clear of Mentioning IranThursday, April 16th, 2015
President Barack Obama recognized Holocaust Remembrance Day that was marked in Israel on Thursday with a splendid statement against anti-Semitism while ignoring Prime Minister Binyamin Netanyahu's remarks last night that noted that Iran is preparing to murder 6 million Jews in Israel with a nuclear weapon.
Obama dutifully said, "Never Forget" and "Never Again" and added:
Yet, even as we recognize that mankind is capable of unspeakable acts of evil, we also draw strength from the survivors, the liberators, and the righteous among nations who represented humanity at its best.
With their example to guide us, together we must firmly and forcefully condemn the anti-Semitism that is still far too common today. Together we must stand against bigotry and hatred in all their forms. And together, we can leave our children a world that is more just, more free, and more secure for all humankind.
Netanyahu has asked that if President Obama is so sure his deal with Iran can stop the regime in Tehran from procuring a nuclear warhead to be aimed at Israel, all Iran has to do to signal its peaceful intentions is to recognize Israel as a country.
Obama rejected the idea out of hand, explaining that it is not practical because it would ruin his deal with the Islamic Republic.


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The past three decades have witnessed steady growth in our ability to harness DNA branched junctions as building blocks for programmable self-assembly of diverse supramolecular architectures. The DNA-origami method, which exploits the availability of long DNA sequences to template sophisticated nanostructures, has played a major role in extending this trend through the past few years. Today, two- and three-dimensional custom-shaped nanostructures comparable in mass to a small virus can be designed, assembled, and characterized with a prototyping cycle on the order of a couple of weeks.
Structural DNA nanotechnology [1,2] pursues the construction of devices on the 10–100 nm scale through self-assembly of DNA strands. The greatest advantage of using DNA for nanoconstruction derives from the strong predilection of DNA for adopting Watson-Crick pairing, if it is available, to yield double helices of very regular structure; a base pair typically is 2.0 nm in diameter and 0.34 nm in height with a twist of 34–35 degrees. Each segment along a given strand can be programmed to pair with a different partner, therefore various branched junctions (e.g. Figure 1A) are possible. The antiparallel double-crossover motif [3,4] (Figure 1B), where two double helices are held in parallel by two pairs of antiparallel strand exchanges, has emerged as a particularly useful building block for nanoconstruction. This motif can be conceived as akin to a rigid Lego tile that can be arrayed into two- and three- dimensional lattices of custom size and shape [5] (Figure 1C).
A principal mission for the field is to generate exact structures of ever increasing complexity. Imagining a custom-shaped tapestry composed of a vast number of unique tiles that each occupy a specified physical address is trivial, yet coaxing real double-crossover tiles to coalesce into such large assemblies with appreciable yield is not. Ascension to successive vistas of complexity over the next twenty years will critically depend upon continuous innovation in one key area: suppression or circumvention of DNA–self-assembly errors. The DNA-origami method [6], which employs a long, enzymatically produced single strand as a majority of the assembled mass, has emerged in recent years as an important foundation for decreasing self-assembly errors and thereby realizing more complex nanostructures. This review will focus on progress in the field towards advancing DNA-origami capability; some potential applications will be briefly mentioned (for another perspective, see here [7]).
In our view, the second greatest advantage of DNA for robust self-assembly of complex nanostructures results from the availability of biologically evolved polymerases that efficiently catalyze sequence-complementary monomer addition for faithful replication of long DNA strands. Nanoconstruction with long strands confers the entropic advantage endowed by pre-organization of its component segments at high effective concentration with perfect control over the intended stoichiometry. However, generalized production of highly homogeneous populations of informational molecular polymers that each are thousands to millions of units in length demands extremely accurate and robust elongation, which only is accessible today through the use of enzymes with relatively low error rates (e.g. for DNA polymerases, 1E-04 or better). Artificial polymer platforms (e.g. peptide nucleic acids, peptoids) will not be compatible in a practical sense with an extensive scaffolded-assembly strategy until comparably accurate enzymatic or enzyme-like synthesis becomes accessible (e.g. through creation of variant polymerases or ribosomes [8]). In the meantime, such aqueous-compatible polymers can be combined with DNA into hybrid materials that offer the combined functionalities of their constituent parts.
In DNA origami [6] (foreshadowed by [9]), one starts with a long single strand that acts as a scaffold, most commonly the 7.3 kilobase genome of the M13 bacteriophage, and mixes it with hundreds of chemically synthesized oligonucleotides, typically 20 to 50 nucleotides in length, that are programmed by Watson-Crick sequence complementarity to act like staples to pinch the scaffold into an antiparallel array of helices after rapid heating followed by slow cooling over the course of an hour (Figure 2A). Neighboring helices are held together by strands that cross over through a bridging phosphate, as in the double-crossover motif. Each helix can be designed with a different length, thus it is as if a designer has two ribosomes worth of molecular silly putty that can be molded by self-assembly into any desired two-dimensional cookie-cutter shape; realized examples from independent groups include a smiley face [6], dolphins [10], and a map of China [11] (Figure 2B). Remarkably, DNA origami efforts to date have not required sequence design, tight control over staple-strand stoichiometry, or purification of staple strands. This robustness is a testament to the entropic advantage of using long strands for scaffolding.
DNA-origami domains can be linked together in various ways. The simplest strategy preserves coaxial stacking of double helices, through either blunt-end or sticky-end cohesion. Origami also can be linked along the axis orthogonal to the helices by shared staple strands that cross over from the helix on the bottom of one monomer to the helix on the top of the next. It is striking, however, that no lattices anywhere near in size to those achieved for simpler multistrand-based tiles (e.g. [12]) have been reported with DNA origami; success may await significant improvements in the folding quality of constituent origami monomers. Domains also can be linked with their respective helical axes at an angle, for example to build a triangle [6] (Figure 2B).
By shifting the register of crossovers along adjacent interhelical interfaces, DNA sheets can be programmed to roll along their helical axes into tube-like structures, such as six-helix bundles [13] and prisms with three, four, or six flat-origami faces [14] (Figure 3). Such domains can be combined to form wireframe polyhedra with open faces, such as an icosahedron built from six-helix struts that is 100 nm in diameter [15]. A box with closed faces roughly 40 nm per dimension can be generated by attaching a square lid to the two open faces of a square nanotube built from four flat-origami faces. One such box was generated with a top lid attached along a flexible hinge on one wall and two "locks" along the the opposite wall in the form of DNA double helices with a "toehold" extension; this extension allowed for opening of the lid by addition of "key" complementary strands [16]. A similar box was generated that can be assembled in two steps, with the second step closing two sets of three walls using a total of nine face-sharing staple strands [17]. Using a quite different approach, a tetrahedron with solid faces has been constructed, with edges that are 54 nm long [18]. In this case, the four triangular faces are not constructed from modular domains of the scaffold. Instead, the scaffold strand passes one helix at a time through each face, such that only two hairpin turns are present in the entire structure.
Sheets of DNA helices can be stacked upon each other to create multi-layer structures, which can be advantageous when greater rigidity or complex three-dimensional cavities and surfaces are desired. The cross section of a multi-layer structure can be designed such that the helices fall either on a honeycomb lattice [15] (Figure 4A) or a square lattice [19], where stability is enforced by strand crossovers between all or most adjacent helices. The honeycomb lattice is more convenient for building objects with a hexagonal cross-section, and enables construction of objects that are more rigid per unit mass, due to the greater cross-sectional area that is afforded. The square lattice is more convenient for building objects with a rectangular cross-section, and enables construction of flatter surfaces, finer grade cavities, and denser objects. Multi-layer origami have the disadvantage that folding requires up to week-long folding times and produces lower yields [15]. As with single-layer origami, helices can be designed with different lengths, and separate domains can be connected together in various orientations. In this way, a variety of honeycomb origami have been demonstrated, including a slotted cross about 30 nm in diameter [15] (Figure 4B).
Further design versatility can be obtained by introducing structures whose helical axes supertwist and bend [20]. For example, increasing the number of base pairs in between crossovers leads to locally underwound helices and a compensatory global right-handed supertwisting of the helical cross-section. Alternatively, if the number of base pairs between crossovers is increased on one face of a nanostructure and decreased on the other face, then the respective supertwisting moments cancel out. However, now the face with deletions is under tension and the face with insertions is under compression. The structure relaxes this stress somewhat by global bending of the axis of the nanostructure towards the face with deletions. These principles were used for multi-layer honeycomb structures to create 60-helix ribbons that supertwist in either direction, 18-helix beams that bend up to 180 degrees with a radius of curvature as tight as 6 nm, and more complex structures such as square-toothed gears (Figure 4B).
For creation of increasingly complex DNA nanostructures, the availability of powerful software design tools becomes a rate-limiting factor. An open-source package, caDNAno, greatly aids the design of single-layer and multi-layer origami on either a honeycomb [21] or square lattice [19]. Other software packages are available as well, for example the SARSE program that was used to design a cookie-cutter dolphin and a single-layer box [10]. As our ability to suppress self-assembly improves, there will be a need for increasingly sophisticated CAD programs.
Another important step for increasing complexity will be to transition from M13-based to designed-sequence scaffolds. The cost per base pair of gene synthesis has been dropping steadily [22]. Low-cost enzymatic or biological synthesis of scaffold sequences that each are specially customized for folding one particular nanostructure will re-introduce sequence design as a key accessible parameter for improving the speed and robustness of DNA-origami folding, which in turn will be required for assembling more complex three-dimensional nanostructures. Recent methods that enable the use of double-stranded DNA as a source of scaffold that can be fed directly into the folding reaction, made possible through combined thermal and chemical denaturation followed by a quick drop to a lower temperature [23], or else methods that enable selective purification of one strand of a PCR product, such as through introduction of a biotin into only one of the primers [24], further enhance our ability to use diverse and longer scaffold sequences beyond what is available from M13. Low-cost gene-synthesis technology also makes more attractive the use of single-stranded DNA origami, where few or no staple strands are used, instead most interactions are programmed to occur via intramolecular base pairing within the long template strand [25-29]. Furthermore, if all the DNA is produced enzymatically or biologically, this raises the long-term prospect of large-scale production of industrial quantities of DNA eventually at a cost similar to other biologically produced commodities such as cotton.
Chemically synthesized DNA is much more heterogeneous than DNA polymerized by enzymes directed by a clonal template, thus the latter provides a possibility for supplying higher quality staple strands to the folding reaction. Here a Type IIS restriction endonuclease might be used to liberate short staple strands from a longer linear template; these clonally–derived, high–quality oligonucleotides can be expected to be advantageous in other applications where high quality is critical, such as DNA computing, where heterogeneities presumably contribute to leakage errors. The long thermal folding ramps currently required for assembling multi-layer DNA origami undoubtedly result in considerable depurination and strand scission defects [30], both in scaffold and staple strands. The use of chemical instead of thermal denaturation may lessen this type of damage [31]. Further optimization of origami architecture and DNA sequence, introduction of folding chaperones, and other strategies such as isothermal active self-assembly to guide the folding pathway or to implement error correction may be useful in reducing the amount of time that the DNA must be subjected to harsh thermal regimes.
Patterning on a rectangle can be enabled by synthesis of two sets of staple strands [6]. For example, a "zero-bit pixel" set specified folding of the scaffold into a rectangle, and a "one-bit pixel" set was identical to the first, except that a hairpin dumbbell was programmed to extrude out of the plane of the rectangle for each of the strands. Then any custom bitmap pattern, for example a map of the Americas, could be created by mixing and matching subsets of strands from the two pools. DNA origami can be used to capture other DNA strands after initial formation [32], with potential application in nanoarray-based sensing [33,34]. DNA origami also have been used as rigid, information-bearing seeds for templating low–error-rate algorithmic assembly of multistrand tiles into cellular automata to build patterns such as binary counters [35] and Sierpinski triangles [36].
DNA origami can be used to template the organization of other matter. DNA origami have been used to template protein guests [37-41] and metallic nanoparticle arrays [42,43], to provide a calibration tool for super-resolution optical microscopy [44]; to self-assemble a cross-junction of carbon nanotubes into a field-effect transistor [45]. Even weak organization can be useful; for example, DNA origami have been used as a weak alignment medium for enabling NMR structure determination of membrane proteins [13].
It is very challenging to maintain long-range coherence by self-assembly, as small errors can accumulate into a large defect over long distances. To scale towards greater lengths, a useful strategy will be to take advantage of top-down strategies to enforce long-range order on a large number of DNA-origami structures. A promising early step has been taken in demonstrating the shape-complementary docking of DNA origami on electronics-compatible surfaces patterned by electron-beam lithography [46]. Here the microfabricated surface can template the microscale position of origami monomers, each of which in turn can template the nanoscale positioning of guest molecules [47]. Origami also have been positioned between nanoelectrodes using dielectrophoretic trapping [48].
Scaffolded DNA origami has been recognized as revolutionary because its entropic advantage has enabled researchers to bypass requirements for sequence design, strand purification, and strand stoichiometry control, and thereby rapidly prototype intricate aperiodic nanostructures more than an order of magnitude larger in size than what has previously been possible. However, it may be necessary to introduce sequence design and production of higher-quality staple strands in order to achieve good yields of solid, three-dimensional DNA nanostructures of considerably greater complexity than is practical to achieve today. Fortunately, automated sequence design and low-cost production of clonally derived staple strands appear as achievable objectives for the not-too-distant future. Ultimately, we expect to see development of a large number of strategies for decreasing self-assembly errors, where each method only offers a modest improvement, but the combined effect of many such strategies applied in tandem result enables a large jump in complexity over what can be achieved today.
This work was supported by Claudia Adams Barr Program Investigator, Wyss Institute for Biologically Inspired Engineering, and NIH New Innovator (1DP2OD004641-01) grants to W.M.S.
Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's Canada Institute for Scientific and Technical Information in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Garlic Rosemary Scallop Kabobs
26 Jul 2010
|Frozen scallops
|2 Pound (American Pride)
|Red bell peppers
|2 , cut in 1 inch squares
|Olive oil
|1⁄2 Cup (8 tbs)
|1 Tablespoon, crushed with a spoon to bring out flavor and make smaller pieces
|3 Clove (15 gm), finley minced
|Garlic powder
|1 Tablespoon
|Kosher salt
|1 Teaspoon
|Black pepper
|To Taste
1, Thaw scallops overnight in the refrigerator.
2, Marinate scallops and peppers in olive oil, rosemary, garlic, salt and black pepper to taste for 30 minutes.
3, Preheat grill.
4, Thread peppers and scallops alternately onto skewers, using 4 scallops per skewer.
5, Cook on a very hot grill for 2 1/2 minutes per side, or until scallops are done.
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Garlic Rosemary Scallop Kabobs Recipe


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5 Things You Need to Know About the Beef Recall
Some 9 million pounds of meat have been recalled. Here's what you need to know.
A Tough Guy Comes to Terms With His Troubled Past
Plus: How the Drug Cartels Took Over Mexico
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Whether you love Martha Washington, Betsy Ross, or you're just a history buff the Colonial Lady Child Costume is calling your name. Features pink and blue dress with apron detail and matching bonnet.
Show some patriotism with this red, white and blue classic Betsy Ross child costume! Great for reports, pageants, plays and trick-or-treating! The patriotic outfit comes complete with dress, cap and star spangled apron.


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Tennis Polls
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[5] More Slam titles- Federer or Nadal
[6] Rome 2012
[7] Clijsters vs Sharapova- who ends up with more slams (in singles) or the same
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It's that time of year, as a popular collegiate tournament takes over the hoops spotlight. Good luck with your brackets! The final month is always "silly season" in the NBA — players get shut down early on bad teams and rested frequently on good teams, just in time to affect the playoffs in traditional Head-to-Head fantasy leagues. [Read more…]
Fantasy Spin: Grizzlies, Warriors Stars Well Rested
It's not the greatest Saturday night in NBA history. There are six games, involving many tired teams, with some coaches resting their stars for the upcoming playoff grind and others — their seasons effectively over — experimenting with lineup combinations and evaluating players for the future. [Read more…]
Fantasy Spin: Cavaliers-Spurs Key To DFS Action
One day after getting almost everything right, my Wednesday picks were as off-target as a DeAndre Jordan free throw. Just kidding, big guy. Jordan and Chris Paul slowed down the Russell Westbrook MVP Express and beat the Thunder on a night of NBA surprises. [Read more…]
Marks: Dreaming of the Day When Sixers' Master Plan Comes True
PHILADELPHIA – Joel Embiid passed the ball effortlessly, the navicular bone in his broken left foot hardly seeming to present a problem. His endearing smile lit up the place and thrilled the crowd, happy to see their hoops savior looking well and wondering if the civic basketball nightmare was about to finally end. Don't worry, Sam Hinkie. Nobody's raining on your "parade,'' which continues to look more and more like the only celebration Philadelphia 76ers fans will ever see — if
Tweet of the Night: Amid Love's Uncertain Future, Wolves Add Veteran Leader
It seems the only thing that you hear about the Minnesota Timberwolves these days is the on-again-off-again, never-ending swirl of Kevin Love trade talks. Whether the other team involved is the Cleveland Cavaliers, the Chicago Bulls or the Golden State Warriors, it almost seems to go on forever. Where will Love end up? As of now, no one knows. What we do know, as of Monday, is that the Wolves president of basketball operations and head coach Flip Saunders has added some
Sheridan Hoops Rookie Rankings: Week 23
This is the final edition of the Rookie Rankings, and we will allow Kobe Bryant to have the final word on a race that was decided long ago. Bryant is a student of the game who understands its history and normally is not given to hyperbole. So when he offers an evaluation of an opponent – most of whom he holds in disdain – it should not be taken with a grain of salt. And here's what he had to say about
Euroleague Update: Ricky Hickman Rising, Nemanja Bjelica to Minnesota This Summer?
If Anadolu Efes is supposed to have merit as a contender, they sure aren't supposed to let a team with ten losses take them to overtime in their own building. But for a second straight week, Jordan Farmar scored 20-something and Istanbul's darlings resisted the urge to tumble into their old ways, closing it out against Bamberg 89-86. [Read more…]
Sheridan Hoops Rookie Rankings: Week 16
Thomas Robinson just caught a huge break. With the possible exception of Austin Rivers, Robinson had been the most disappointing 2012 lottery pick this season. An All-American and the Big 12 Player of the Year, he went fifth overall to the Sacramento Kings, who weren't exactly loaded in the frontcourt. There appeared to be an opportunity for Robinson to make an impact as a rookie, but he did not. He has averaged 4.8 points and 4.7 rebounds in just under 16 minutes.


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And then she herself becomes a sarsaparilla vine, the reasons of which are unclear.
tropical American plant, 1570s, from Spanish zarzaparrilla, from zarza "bramble" (from Arabic sharas "thorny plant" or Basque sartzia "bramble") + parrilla, diminutive of parra "vine," which is of unknown origin. Hence, also, "a medicinal preparation of sarsaparilla" (1570s). In 16c.-17c. the dried roots were held to be efficient in treatment of syphilis.


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Photo SpecialTweet & Eat! What Your Favorite Stars Are Eating & Drinking Right Now
Peek at the plates of Padma Lakshmi, Jessica Alba and more celebs who are making us hungry!
Credit: Courtesy Mindy Kaling; Inset: Getty
Updated: Friday Apr 25, 2014 | 01:40 PM EDT By: Rosa Heyman
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Originally written on Fox Sports | Last updated 1/18/13
Rodney McGruder is settling into first-year coach Bruce Weber's offensive scheme, and that's a big reason Kansas State is on the verge of its longest winning streak in more than three years. Oklahoma is looking to continue its own lengthy run. McGruder tries for another strong offensive showing as the No. 16 Wildcats seek an eighth straight victory Saturday against the Sooners. McGruder leads Kansas State (14-2, 3-0 Big 12) with 15.3 points per game, slightly lower than his career-high average of 15.8 from last season. The senior guard initially struggled to learn Weber's offense, averaging 11.9 points on 37.8 percent shooting - 7 of 30 from 3-point range - over the first nine games of the season. But the learning curve seems to be over, with McGruder getting 19.6 points per contest while hitting 50.0 percent from the field - 15 of 36 from beyond the arc - to spark the Wildcats' seven-game winning streak. "I'm able to make shots. It's a lot of fun," McGruder said. "There's a lo...
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Italian Potatoes
Total Time
1hr 10mins
Prep 10 mins
Cook 1 hr
FFA/HERO cookbook.
Make and share this Italian Potatoes recipe from Food.com.
Ingredients Nutrition
- Arrange potatoes in 2-quart casserole.
- Add salad dressing and butter.
- Sprinkle with seasonings and parsley.
- Bake at 350 for 45 to 60 minutes or until potatoes are tender.
Most Helpful
Nice way for potatoes! I wish I had the parsley to add but I was out. The Italian dressing adds a subtle flavor and does not overpower the potatoes. I used a 8x12 baking dish and baked for about 55 minutes.


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Kirk, Spock, McCoy and the rest of the Enterprise crew face another threat to the Federation.
'Star Trek Into Darkness' Stills
22 / 42
Star Trek Into Darkness Still
Paramount Pictures' "Star Trek Into Darkness"
Fifty States of Great: Can You Name Every Movie in Our Great American Supercut?
Yahoo Movies Staff
The 'Frozen' Effect: "Elsa" Re-enters List of 500 Most Popular Baby Names After 97 Years
The Hollywood Reporter


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Corinne L. (Putnam) Clift passed away Sept. 16, 2013 at home in Eaton.
She was a long time resident of Eaton, and Preble County. She was born in Larned, Kansas on Aug. 10, 1935 to Harold and Sylvia Putnam. She was a homemaker and active member of several embroider groups and the Preble County Historical Society. She also served as director of the Preble County Senior Activity Center from 1978 through 1981.
She is survived by her husband Ellis Clift, and their three children, daughter Karen Clift of College Corner, Ohio, daughter, Sharon and husband Alison Walker, of Eaton, and son, Alan and wife Cathy Clift, of Eaton, Ohio. Also surviving is Corinne's sole grandchild Benjamin Clift, of Eaton.
A celebration of her life was held on Monday, Sept. 23, at the Girton Schmidt & Boucher Gard Funeral Home, Eaton, 226 West Main Street, Eaton. Memorial contributions may be sent to Hospice of Dayton, 324 Wilmington Ave., Dayton, OH 45420 or the American Cancer Society, Ohio Southwest Region, 2808 Reading Road, Cincinnati, OH 45206. Online condolences and other remembrances may be sent to the family by visiting www.gsbfuneralhome.com.
The My Memorials Facebook app allows you to:


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Watch Bon Iver on "Fallon" Again
By Tom Breihan on June 22, 2011 at 9:25 a.m. EDT
Just last month, Bon Iver appeared on "Late Night With Jimmy Fallon" to cover Bonnie Raitt and Donny Hathaway/Leon Russell and enthuse about Bruce Hornsby. Last night, Justin Vernon and co. returned to the show, continuing a big media week that also saw the release of their BNM'ed new self-titled album and their appearance on "The Colbert Report". Watch video of Bon Iver performing "Holocene" from Bon Iver below. As ?uestlove Tweeted, "'Holocene' might be the most beautiful moment on @latenightjimmy. i think i just grew some wings." (Also, Kanye was apparently supposed to show up, but didn't.)
Bon Iver Adds Tour Dates
By Larry Fitzmaurice on June 21, 2011 at 12:20 p.m. EDT
Busy week for Justin Vernon's Bon Iver project: Their new self-titled album was slapped with a BNM, they appeared on "The Colbert Report" last night, and now they've announced more tour dates for later this year, too. Check out Bon Iver's full road schedule and the video for bon Iver single "Calgary" below.
Watch: Bon Iver on "The Colbert Report"
By Larry Fitzmaurice and Amy Phillips on June 21, 2011 at 1:30 a.m. EDT
Tonight, "The Colbert Report" kicked off their week-long concert series, "Dr Pepper Presents StePhest Colbchella '011: Rock You Like a Thirst-icane". (Try saying that three times fast.) After jokes about corporate sponsorship, Wheat Thins, and, um, Pitchfork, Colbert introduced the series' first guest: Bon Iver.
Listen: Bon Iver Covers Bonnie Raitt
By Larry Fitzmaurice on June 20, 2011 at 9:40 a.m. EDT
Bon Iver's self-titled effort just got slapped with a BNM this morning; the album comes out today in the UK and Europe via 4AD and tomorrow everywhere else via Jagjaguwar. Disco Naïveté has a stream of Justin Vernon's medley of Bonnie Raitt's "I Can't Make You Love Me" and "Nick of Time", found as the B-side to the single for BNT'd Bon Iver standout "Calgary". Hear it here.
Video: Bon Iver: "Calgary"
By David Bevan on June 15, 2011 at 8:55 a.m. EDT
"Calgary" is the BNT'd first single from Bon Iver's new album, out next week by way of Jagjaguwar (4AD in the UK and Europe.) In the song's equally opaque visual companion, just about everything is up for wild interpretation. Makes sense: the video's treatment was written by Bon Iver's Justin Vernon. (It was directed by Andre Durand and Dan Huiting and produced by Daniel Cummings and Picture Machine Productions).
Watch it below and over at Pitchfork.tv.
Stream the New Bon Iver Album
By Larry Fitzmaurice on June 9, 2011 at 9:25 a.m. EDT
The self-titled new album from Justin Vernon's Bon Iver project arrives June 21 via Jagjaguwar and a day earlier in the UK and Europe via 4AD. Listen to the whole album in its entirety below, via NPR and The New York Times.
A few other new releases are also streaming online right now, and we've also got links to them below.
Watch Bon Iver Cover Bonnie Raitt on "Fallon"
By Tom Breihan on May 24, 2011 at 10:05 a.m. EDT
Last night, Bon Iver rolled through "Late Night With Jimmy Fallon" for a performance and interview. Accompanied by Phil Cook of Megafaun on piano, Justin Vernon covered Bonnie Raitt's "I Can't Make You Love Me" with Raitt's "Nick of Time", along with Donny Hathaway's "A Song for You", written by Leon Russell. As previously reported, the Bonnie Raitt covers are from the B-side to the new Bon Iver single "Calgary". Vernon also sat down with Fallon to chat about the new Bon Iver album. The interview included this amazing sentence: "Man, there's not enough Hornsby in my scene."
Watch the videos of the performance and interview (via the Audio Perv) below.
Echo Chamber: Rick Ross Big Ups Bon Iver
By Larry Fitzmaurice on May 20, 2011 at 4:40 p.m. EDT
"He's a fucking genius. I'd never seen nor heard of him in my life, and I looked up, and I was in a fucking 5-by-5 room with a white guy, smoking weed . . . and his voice is like something I've never heard, and he's using words that are far from common. Within 20 minutes, I realized why Kanye had him there."
-- Rick Ross, singing the praises of Bon Iver's Justin Vernon while describing working with him on Kanye West's My Beautiful Dark Twisted Fantasy. I think I'm Big Meech...Justin Vernon! (via Billboard)
Bon Iver Share Lyrics for New Album
By Tom Breihan on May 19, 2011 at 10:55 a.m. EDT
The self-titled sophomore album from Bon Iver arrives on June 21 (via Jagjaguwar), with 4AD dropping it a day earlier in the UK and Europe. Yesterday, Jagjaguwar posted the album's entire lyric sheet online. Justin Vernon's words are some dense, poetic freeform stuff: "Armour let it through, borne the arboretic truth you kept posing." That sort of thing. Get to parsing!
UPDATE: Bon Iver mastermind Justin Vernon performed this past weekend at the National member Bryce Dessner's MusicNOW Festival in Cincinnati. His old friends in Megafaun performed their "Sounds of the South" project, which reimagines old folk and blues songs recorded by musicologist Alan Lomax. Vernon guested with them. Below, we've got videos of Vernon singing a pair of songs, including a duet with singer-songwriter Sharon Van Etten.
Bon Iver Cover Bonnie Raitt
By Tom Breihan on May 17, 2011 at 1:15 p.m. EDT
Yesterday, the world got to hear "Calgary", the first taste of Bon Iver's forthcoming self-titled sophomore album. The album is due June 21 via Jagjaguwar and a day earlier in the UK and Europe via 4AD. The album can be pre-ordered now in a number of different packages from Secretly Canadian Distribution, and some of those bundles also include a 12" vinyl single of "Calgary". That single's B-side is a cover of two tracks by Bonnie Raitt: the supremely popular 1991 ballad "I Can't Make You Love Me", with a little bit of Raitt's 1989 song "Nick of Time" thrown in at the end.
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The Police concert on June 29 will be the last chance for UK fans to see the reunion tour. The tour will end in North America in August. Speaking to the Sun Newspaper Sting revealed, "The very last show will be in New York in the first week of August - it's our swan song..."
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text: Unfortunately we had a pretty sad experience here. We waited aprx 10 mins for a server to come around. Then we ordered Chimi changa, tamale , pazole and a quesadilla and a margarita. The margarita had a harsh metalic taste. The pazole was not very brothy and the overall flavor was bland. The tamale... read more


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- Drum Set Instruction(497)
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Pediatrician, Endocrinologist (diabetes, hormones), Pediatric Specialist
9 years of experience
Accepting new patients
9 years of experience
Accepting new patients
11 Vanderbilt Park Dr
Asheville, NC 28803 Phone number & directions
Asheville, NC 28803 Phone number & directions
License & Identifications
A medical license is required for a doctor to practice medicine in a particular state. Requirements vary by state but most require, at a minimum, post-graduate training in the doctor's specific specialty. An NPI number is a national identifier unique to an individual health care provider and is managed by the Center for Medicare & Medicaid Services (CMS).
Learn more about Dr. Lori Wagner:
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Patient comments (0)
The overall average patient rating of Dr. Lori Wagner is Excellent.
Specialties & Research
Dr. Lori Wagner, MD is board certified in Pediatrics and Pediatric Endocrinology.
- She has special expertise in 3 areas:
- Diabetes
- Growth Disorders
- Puberty
Education & Awards
Dr. Wagner graduated from University of Mississippi , Jackson.
Dr. Wagner has 4 hospital affiliations:
- Mission Hospitals
- Asheville Specialty Hospital
Home > Find a Pediatrician > NC > Asheville Pediatricians > Dr. Lori Wagner, MD
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- Additional Information
- Dr. Lori Finch Wagner MD is a female Pediatrician, has 9 years of experience and practices in Pediatrics and Pediatric Endocrinology.
- Where does Dr. Lori F. Wagner practice?
- Dr. Lori Wagner has 1 office location.
Dr. Lori Wagner practices Pediatrics and Pediatric Endocrinology near Asheville, NC.
See Asheville Pediatricians and Asheville Endocrinologists.


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It seems the father-daughter bond is the flavour of the season. Post ...
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[BETTER BUT NOT CURED] Spleen tumor in a dog
Hi, I hope this will be of some help to someone out there. My female German Shepherd aged 15yrs was diagnosed with a ruptured spleen tumor and given 2wks to live. She was having injections to stop her bleeding to death every few days but the vets opinion was to put her sleep. This was nearly 6mths ago. I have my girl on 'china 20C', 'ceanothus 3x', aspidosperma 30C, I also give her 1 garlic oil tablet daily, 500mg of Vit C. Her tumor shrunk to a 1/5th of its original size and she's been running around like a 6yr old dog. Unfortunately I think the cancer may have spread and the tumor looks like its has grown again so now I'm googling everything I can to see if I can find anything else to help her. Also, her diet is pretty much carb-free but I have to give her cat food in the morning to get her medication into her which probably isnt doing her any good but its better than not having her meds. If your beloved pooch has this type of cancer, please try these (her new homeopathic vet put her on these) and if you know of anything else I can try - please post it - thanks


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Kerr Memorial Baptist Church would like to take this opportunity to invite you to be our guest and encourage you to take advantage of the many opportunities for worship, fellowship and ministry that are available for all age groups. The mission of Kerr Memorial Baptist Church is to lead individuals to become disciples of Jesus Christ. With Scripture as our authority and love as our motivation, we are to teach individuals to develop a relationship with Jesus Christ, leading them to lifestyles of ministry and evangelism.We all have a story. It is our hope that through our ministry the story of the gospel will intersect the lives of those in our community and become the motivation for new life and eternal hope. Come join us as we fulfill our mission by:
Planting: Connect with us through Worship services and fellowship events.
Cultivating: Grow and develop your spiritual journey through Bible Teaching Sunday Schools, Small Groups and other ministries within the church.
Harvesting: Minister with us through engaging in opportunities to serve our community and world in need. Come be a part of our story as we press forward in the journey of life together.
In His Care, Rev. Darrell Brumfield & Minister to Families, Justin Curry
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