text:
Women Accessing Capital: Overcoming the Psychology of "Small"
Despite reports implying fast growth of women-owned businesses, many still face obstacles related to financing business growth and barriers that are not as prevalent in the male marketplace. This exciting program will provide an advanced approach and strategies to help YOU take YOUR BUSINESS to the next level.
Pre-Meeting Reception: Monday, Oct 15, 2012
Time: 5:30pm until 7pm
Location: Economic Development Corporation- Kansas City Headquarters
Description: A chance to welcome out of town guests and interact with program sponsors and speakers.
**Must Register Separately. Click here to register.
Program Date: Tuesday, October 16th, 2012
Location: Kauffman Foundation, 4801 Rockhill Road, Kansas City, MO
Time: 8am until 5pm
Reception: 5pm until 6pm
This program will address:
· Overcoming the psychology of "staying small"
· Capitalization barriers that restrict company growth
· Tracking and accurately discussing revenue growth and potential in your business
· A hands-on approach to various financing mechanisms available
· How best to position your company to go after financing
Meeting Highlights:
· Keynote Speakers – Don Graves, Executive Director of the President's Council on Jobs and Competitiveness
· Navigating the Capital Maze – Panel Discussion
· Beltway Update: Status of WIPP Core Issues in the 2012 Election – Ann Sullivan, WIPP Government Relations
· Lessons Learned: Keys to Growing Successfully – Amy Millman, Springboard Enterprises
*Speakers and timeframes subject to change
Click here for full meeting agenda.
Sponsorship Packages Available – Click here for more information.
Planning Committee – Click here to view committee list.
Hotel Information: Special Room Rates are available at the Sheraton Plaza Suites in Kansas City. Please specify that you are attending the WIPP event to get the rate when booking.
A shuttle will be available at the hotel to take attendees to and from the reception and event.
If you have any questions please contact AnnaKate Kallay at email@example.com or call 415-434-4314
Remember Me
Forgot your password?
Haven't registered yet?
6/30/2015SBEC - Small Business Summer, SCOTUS Ruling on EPA, and More
6/25/2015WIPP Statement on King v. Burwell Supreme Court Decision on ACA Subsidies
6/24/2015NCRC: Check Out the New Reinvestment Works
7/7/2015WIPP Access to Capital New Platform Briefing
7/14/2015WIPP 2015 Annual Dinner
7/15/2015Give Me 5: Reverse Auctions: When Could They Drive Revenue For You!
7/21/20153rd Quarter WIPP Procurement Committee Meeting
7/21/2015Procurement Committee Meeting - 3rd Quarter 2015


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Victim/Witness Services
Rowan Medicine: A new name for health care in South Jersey | More
New writing scholarship awards three incoming freshmen $35K | More
Rowan winter/summer classes saving students time and money | More
Rowan scholar to study organized crime, terrorism in Eurasia through grant from Department of Defense's Minerva Research Institute | More
In 12 Orientation sessions, new Profs—and their parents—get a formal introduction to Rowan | More
Community Services
Services Empowering Rights of Victims Program (SERV)
SERV is a program which is run by the Center for Family Services, Inc (a nonprofit human services agency). SERV provides 24-hour emergency safe housing, counseling, support groups, outreach, advocacy and accompaniments for victims of violence.
SERV provides free counseling services to victims of violence, and also will provide an advocate to accompany victims and witnesses to court appearances.
SERV also runs an anonymous 24-hour crisis hotline at 1-866-295-SERV (7378). Victims of violence can call this hotline 24/7 and speak to a crisis counselor anonymously.
New Jersey Victims of Crime Compensation Board (VCCB)
The New Jersey VCCB may help ease the financial burden faced by crime victims. Services covered by the VCCB include: benefits for mental health counseling, medical bills, loss of earnings, funeral expenses (up to $5000), crime scene clean-up, relocation expenses, child care/day care services, victims' rights attorney fees, domestic help, and other victim services related to crimes. For further information on filing procedure time requirement and benefit restrictions, please contact the VCCB by phone at 1-877-658-2221 or visit the VCCB website at:

subset: commoncrawl


text:
Scott Kitchen Towels: Coffee
Super absorbent
Advertising Agency: JWT, Kuala Lumpur, Malaysia
13 comments
chriscoastJun 21, 2007 - 5:14
This campaign is very nice.
This campaign is very nice.
But I have a problem with the cup's shadow falling on the table. As it is right now, it looks like a cube's shadow.
mrtalentedJun 21, 2007 - 13:44
the photography and lighting need to be improved though. but nice concept
manuk_esquimalJun 21, 2007 - 17:14
great! i think even the art is cool. Like those liquid things in dali paintings... a little real but a little fake.


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Social Justice
Our Position On Missionaries
The Mazeways They Are A'chang'n ("None's") On The Rise)
Five Questions for Carol Roth
Carol Roth, a staff leader with Native Mennonite Ministries, connects Native Mennonites with the broader Mennonite church.
'Nones' and the Common Good
What will happen to U.S. civil society as the pews empty out?
A Spirituality of Solitude
Marking the centennial of pacifist poet William Stafford
Church to Go
City of God: Faith in the Streets. Jericho Books.
From the Archives: March 1986
Exodus and Community
David Brooks and Religious Hostility: Tasting Goodness
In his New York Times column, " Alone, Yet Not Alone," David Brooks laments the "strong vein of hostility against orthodox religious believers in America today, especially among the young." Even more disturbing for Brooks is that in his experience, the opinion of young people is too often justified. He observes that religious believers can be "judgmental," "hypocritical," "old-fashioned," and "out of touch," and he wonders why that's so. Brooks, who is Jewish, knows that the Judeo-Christian tradition reveals a God who desires mercy and not sacrifice, who calls us toward a radical love that includes our enemies. As evidence of the core of orthodox belief, he offers two giants of the Judeo-Christian tradition, Rabbi Abraham Heschel and Augustine, who give testimony to lives of compassion and love inspired by devotion to the biblical God. Lives that tolerate ambiguity and uncertainty as essential components rather than disqualifiers of faith.
So what gives? Why do religious believers spend so much energy reinforcing their (our – I'm one of those orthodox believers) borders, building thicker and higher dividing walls designed to keep out the underserving, the sinners whom not even God can love? Just who is kept out varies widely, but it seems religious people are utterly convinced that they are on the inside with God. No doubt about it. Musing on this sad fact, Brooks comments:
There must be something legalistic in the human makeup, because cold, rigid, unambiguous, unparadoxical belief is common, especially considering how fervently the Scriptures oppose it.
Brooks is on to something here – there is something rooted in our "human makeup" that the Scriptures fervently oppose, but it is not legalism per se.


text:
Dear All,
I am trying to insert a newline char in mcs51 assembly code (which is part of a c macro). However sdas8051(#6622 snapshot version) is giving error as "Error: <q> missing or improper operators, terminators, or delimiters"
The macro is as below:
#define CAN_pushAMRegs() while(CAN_ADCON & CAN_ADCON_BSY); \
_asm \
push SDCC_CAN_ADL \
push SDCC_CAN_ADH \
push SDCC_CAN_DATA0 \
push SDCC_CAN_DATA1 \
push SDCC_CAN_DATA2 \
push SDCC_CAN_DATA3 \
I want to include a \n after every push instruction. As per v3.0 usermanual I tried using '\n. However, the assembler is not printing a newline as desired. I request you to let me know how to do it.
Best Regards,
You can't insert a newline by using the C preprocessor macro definition, but the following trick should solve your problem:
#define CAN_pushAMRegs() while(CAN_ADCON & CAN_ADCON_BSY); \
__asm push SDCC_CAN_ADL __endasm; \
__asm push SDCC_CAN_ADH __endasm; \
__asm push SDCC_CAN_DATA0 __endasm; \
__asm push SDCC_CAN_DATA1 __endasm; \
__asm push SDCC_CAN_DATA2 __endasm; \
__asm push SDCC_CAN_DATA3 __endasm;
Tormod Volden
Note that your trailing slashes get "eaten" by the preprocessor while it parses your macro. So the macro itself will just be one long line with all your things concatenated. Borat's suggestion will work because the semicolons separate statements that are on the same line. Maybe it will also work to use \n\ at the end of each line (maybe this was what the documentation meant). Can you please tell which section of the documentation you are referring to?
In Borat's example you will have to add braces {} around the while loop contents, otherwise only the first "push" will be in the loop, as it constitutes a full C statement.
And in all of above, there should be no semicolon after the while() conditional, otherwise the loop will be just the empty statement.
> Borat's suggestion will work because the semicolons separate statements that are on the same line.
It is not a semicolon: each __asm / __endasm pair generates an additional newline in the assembly code.
> Maybe it will also work to use \n\ at the end of each line
No, it won't: the preprocessor doesn't convert \n to a newline, so the \n is passed literally to the compiler and in this case to the assembly code.
> In Borat's example you will have to add braces {} around the while loop contents
I didn't pay attention, but this was already wrong (if it is wrong at all) in the original example.
P.S.: it seems that I have new nick name ;-)
Tormod Volden
lol, oops, sorry about the name mix-up :) I thought the semicolon separates the __asm / __endasm C statements, from the C point of view at least. But what the assembler ends up with I do not know very well.
In the original example, the one statement to the while loop (if the semicolon is omitted) is the one __asm/__endasm statement. Well, I /think/ the __asm/__endasm constitutes a C statement, otherwise I am awfully wrong.
> In the original example, the one statement to the while loop (if the semicolon is omitted) is the one _asm/__endasm statement.
Correct. With "this was already wrong" I meant the semicolon after the while(). Curly brackets are required.
> Well, I /think/ the __asm/__endasm constitutes a C statement, otherwise I am awfully wrong.
Yes, __asm/__endasm constitutes a C statement.
Both the semicolon after the while condition in the original post as well as the ones after the __endasm parts end a C statement and thus braces are necessary if multiple __asm/__endasm pairs are used. The O/P may have really meant to have no statement in the wait while busy loop.
Using _asm (single underscore) is depreciated and on top of that not recognized by the preprocessor. So the preprocessor cannot replace the backslashes in the macro with "__endasm; __asm" pairs to solve your problem. If you use __asm (double underscore) it will. See also bug 1505956 why all this is necessary. And the regression test bug1505956.c which shows it works.
BUG: https://sourceforge.net/tracker/index.php?func=detail&aid=1505956&group_id=599&atid=100599
TEST: http://sdcc.svn.sourceforge.net/viewvc/sdcc/trunk/sdcc/support/regression/tests/bug1505956.c?revision=6841&view=markup
There may still be a bug lurking here as the preprocessor probably doesn't emit braces either while it does break up the inline asm instructions into multiple C statements.
It appears that _asm and _endasm are not yet depreciated by the lexer when using -std-sdccXX. This should (will) change soon.
It also appears that _asm IS recognized by the preprocessor so the original code should work as is.
And the missing braces bug is indeed there.
Borut Ražem
Maarten, can you give an example of missing braces bug?
#define NOP __asm \ nop \ nop \ __endasm while (busy) NOP;
The preprocessor changes the code into:
while (busy) __asm nop __endasm; __asm nop __endasm;
And thus it will not do two NOP's in the loop body.
Dear All,
Thanks for all the quick replies. Sorry for my late replies.
@Borut, @Maarten: Thanks for your advices.
In the above example, the while loop is a busy loop, so no statements in the wait state (@Maarten : you got it right :-) )
The following are my observations:
The preprocessor seems to be recognizing the _asm. However not replacing backslash with "__endasm; __asm";
When __asm …. __endasm (double underscore) is used with the rest of the above example as is, it still does NOT replace backslash with "__endasm; __asm"; the reason is : there are some #defines inside the asm code (e.g.: SDCC_CAN_DATA0, SDCC_CAN_ADL etc., in push instruction). However, if I replace the SDCC_CAN_ADL, C_CAN_DATA0 etc., with literal addresses like 0xDB, 0xDC, it works FINE.
Does it mean the preprocessor can be further improved to solve this? Kindly provide your thoughts on this.
Thanks & Best Regards,
Raghunath Lolur.
Why use defines for SDCC_CAN_ADL if you can also create a real symbol for it? Is it an sfr that is defined in a C header? Then you can use the C name with an extra underscore in assembly.
__sfr __at(0xDB) CAN_ADL; __asm push _CAN_ADL __endasm;
Still the preprocessor should not forget it is inside an __asm/__endasm pair when it encounters another macro.
Robas Teodor
Hello all,
Just did some code porting and I have noticed that both compilers had a very convenient "__asm ()" function.
So macros like:
#define SOME_MACRO \ __asm("\tpush r16"); \ __asm("\tst.w 3, r16"); \
put no problems. Is there a reason for not having this in SDCC ?
Borut Ražem
> The preprocessor changes the code into:
> while (busy) __asm nop __endasm; __asm nop __endasm;
What a surprise! Obviously I forgot that Maarten implemented it!
This changes almost everything that I wrote :-(
The second surprise is a different behavior between single underscored _asm / _endasm and double underscored __asm / __endasm. Usage of single underscored variant is deprecated but not obsoleted so by my opinion it should work the same as the double underscored variant.
Actually I think there is no difference currently. I just remembered (wrongfully) that only __asm was recognized. But I sure would not add code for already deprecated keywords to fix very long standing bugs. Unfortunately _asm is not yet marked deprecated.
Here is the content of my test case file t.c:
int main(void) { #define NOP __asm \ nop \ nop \ __endasm NOP; #define NOP1 _asm \ nop \ nop \ _endasm NOP1; return 0; }
$ sdcpp t.c generates (blank lines excluded):
# 1 "t.c" # 1 "<built-in>" # 1 "<command line>" # 1 "t.c" int main(void) { __asm __endasm; __asm nop __endasm; __asm nop __endasm; __asm __endasm; _asm __endasm; __asm nop __endasm; __asm nop __endasm; __asm _endasm; return 0; }
so _asm works the same as __asm. Yesterday I probably made a mistake while testing, sorry.
$ sdcc -S t.c
t.c:15: warning 197: keyword '_asm' is deprecated, use '__asm' instead t.c:15: warning 197: keyword '_endasm' is deprecated, use '__endasm' instead
So single underscored _asm is deprecated by sdcc (not by sdcpp), which I think is OK.
The implementation of __asm / __endasm generated by preprocessor for each line in macro definition introduced a new problem, since a single C statement in source file is by preprocessor devided in sveral C statements. I don't know if the surroundig curley braces sole this problem. Maybe the { .. } while(0) preprocessor trick is more appropriate?
__asm("…"); seems not a bad idea. This approach doesn't require any special handling by cpp, which siplifies the life a lot. But this also means that using macros in the asm strings doesen't works since literal string are not preprocessed. Is this correct or I'm missing something?
Probably both __asm("…") and __asm / __endasm methods can even co-exist if the grammer analyser is smart enough…
Actually the preprocessor trick is:
do {...} while (0);
See http://uw714doc.sco.com/cgi-bin/info2html?(cpp.info)Swallow%2520Semicolon&lang=en
Maarten Brock
I don't see how __asm(…) solves the problem unless it is restricted to one single mnemonic only. In that case you might as well use __asm … __endasm; with only one mnemonic. I have no objections against also supporting __asm(…) as others have already proposed in the past though.
And we probably need the trick for a proper fix.
When I tested _asm I did not get a warning. Maybe I did something wrong too. I'll test again later.
> I don't see how __asm(…) solves the problem unless it is restricted to one single mnemonic only.
Something like __asm("nop\nnop") would also work since the newline is properly transferred to the assembler and the __asm(); is still a single C statement. But a new problem arises: what about the indentation of mnemonics?….
Maarten Brock
Ah, right. So __asm("…") needs the argument as a string. This precludes macro expansion, but apparently that doesn't work properly now either. And instead of the line continuation character (\) you need to use \n. Indentation is copied from the string then as long as you use spaces and no tabs.
__asm( " cpl a ; comment 1 \n" " cpl a ; comment 2 \n" );
Or, if you want to write unreadable and unmaintainable code:
__asm("\tcpl\ta\t; comment 1\n\tcpl\ta\t; comment 2\n");
> This precludes macro expansion, but apparently that doesn't work properly now either.
Macro expansion does work. INSTR is properly expanded to nop in the following example:
#define INSTR nop __asm INSTR __endasm;
In __asm(…); syntax the macro expansion can be done by stringifying the mcaro value:
#define STRINGIFY(x) #x #define S(x) STRINGIFY(x) #define LABEL 100 asm("jmp " S(LABEL));
gcc used asm or __asm__ keywords. If we could use the same kewords (maybe only __asm__), so both __asm / __endasm and __asm__ (…); can coexist.
For solving the indentation the GCC-Inline-Assembly-HOWTO document at http://www.ibiblio.org/gferg/ldp/GCC-Inline-Assembly-HOWTO.html proposes the following coding style:
__asm__ ("movl %eax, %ebx\n\t" "movl $56, %esi\n\t" "movl %ecx, $label(%edx,%ebx,$4)\n\t" "movb %ah, (%ebx)");
Maarten Brock
The bugs are fixed in SDCC revision #6852. The preprocessor can handle macros inside other macros now. And instead of '__endasm; __asm' the preprocessor now inserts '‡' (0x87) for line continuations inside an __asm / __endasm block. The code generator replaces those '‡' characters by newlines.
As you see asm in gcc permits passing values to and from assembler block:
asm ("movl %1, %%eax; movl %%eax, %0;" :"=r"(b) /* output */ :"r"(a) /* input */ :"%eax" /* clobbered register */ ); asm ("cld\n\t" "rep\n\t" "stosl" : /* no output registers */ : "c" (count), "a" (fill_value), "D" (dest) : "%ecx", "%edi" );
This is VERY VERY required feature for this compiler. Because many operations can be done inline. For example memcpy for z80:
__asm("ldir\n\t" : /* no output registers */ : "hl" (src), "de" (dst), "bc" (size) : "hl", "de", "bc");
I suggest gcc-like syntax (with classic assembler - not AT&T):
asm("<STRING>" : "=<REG>"(<var>) : "<REG>"(<var>) : "<REG>" )
where <STRING> - assembler text (can be empty)
<REG> can be:
"r" - any 8 bit register
"rr" - any 16 bit register (or register pair)
"<register name>" - name of standard for corresponding CPU register (for example: A, HL, R0…)
"<register1 name>,<register2 name>" - for values greater than one register/pair can hold (for example: "d,e,h,l"(var) - will load to de:hl value of 32-bit variable var; d - MSB, l - LSB)
Related issues:
please add asm() pseudo function as alternate
Register parameter passing
PIC16: Inline assembly: accesssing of function arguments
A new "class" of functions


text:
Gourmet Popsicles
Skip the same-old sorbet and let these refined frozen treats wow you with punchy flavors that tempt the tastebuds.
We've all been there—after a savory feast, lusting for a sweet fix, you find that the only dessert option is a less-than-exhilarating, freezer-burned scoop of lemon or raspberry sorbet. Bore yourself no more! San Francisco-based Pop Nation is here to put the "fun" back into "froz(u)n" with an impressive slew of gourmet ice pops in flavors that are beyond groovy. Both sweet 'n' salty make their way into these gluten-free, all-vegan delights, which come in wowing combos like strawberries 'n' cream with basil, avocado-cilantro, and Earl Grey-lavender. And with spring temperatures climbing fast, we're thinking of keeping a cooler full of these bad boys right next to our lawn chairs. Be cool, man.
Vegan White Cheddar Snacks
These cheese puffs make the perfect summer snack.
Read More »
Raw Coconut Water
Skip the sugary stuff and enjoy electrolyte-laden bliss with Harmless Harvest's coconut water.
Read More »
Edamame Hummus
This creamy soybean-based hummus makes it worthwhile to cheat on chickpeas.
Read More »
Indian-Spiced Popcorn
Crunchy and exotically appetizing, Masala Pops Eastern-inspired popcorn will infuse a festive flair into an ordinary lunch break.
Read More »
Marvelously Moisturizing Vegan Body Butter
Keep your skin supple and soft this spring with The Orange Owl's exclusive body butter line.
Read More »
More Flashbacks
- Vegan White Chocolate Peanut Butter
- Raw Vegan Chocolate Truffles
- Chocolate-Coconut Spread
- Almond Milk-Coffee Drinks
- Vegan Candy Cane Cookies
- Holiday Cranberry Roast En Croute
- Mint Chocolate Coconut Milk
- Pumpkin Spice Coconut Milk
- Salted Chocolate Caramels
- Vegan Macarons
- Crunchy Chickpea Snacks
- Luscious Artisan Vegan Caramels
- Vegan Frankfurters
- Beefless Burgers
- Garlic & Herb Buttery Spread
- Festive Vegan Cheese Shreds
- No-Nut Butter
- Animal-Friendly Sunglasses
- Fruity Sorbet Pops
- Vegan Body Butter


text:
Montgomery County police say they plan to release details about sexual abuse allegations involving a substitute teacher.
Bank Teller Charged With Stealing $42K From Vault
Rockville police have arrested a bank teller for allegedly stealing $42,000 from the bank's vault.
Police: Suspects Sought After Double Shooting In Gaithersburg
Montgomery County Police confirm a double shooting in the 18000 block of Premiere Court in Gaithersburg.
Ex-Student Charged With Bringing Gun To School
Rockville City Police have arrested a former high school student they say brought a gun onto school property.
2 Shot During Attempted Robbery In Gaithersburg
Montgomery County Police say two people were shot during an apparent robbery attempt at a Gaithersburg business.
Md. Officials Rescue 6 From Shipping Container
Authorities in Maryland say six workers had to be rescued after a shipping container they were working in tilted on one end and trapped the workers inside.
Detectives Continue To Investigate Fatal Montgomery County Stabbing
Detectives continue to investigate a stabbing in Montgomery County.
Body Of Missing NIH Scientist Found Near Wrecked Car
Police say the body of a Gaithersburg man missing since Aug. 21 apparently has been found in western Maryland.
Missing NIH Scientist Found Dead In Allegany County
Police have identified a man found dead in an abandoned vehicle Thursday afternoon as 54-year-old Martin John Rogers.
Family Asks Public For Help In Finding NIH Researcher
The search for a missing NIH researcher from Maryland expanded into Pennsylvania and West Virginia.
Two Killed, One Injured In Gaithersburg Car Crash
Montgomery County Police say two men were killed and a third was hurt when their SUV hit a tree in Gaithersburg.
Quadriplegic Md. Army Veteran And Wife Rescued From House Fire
Neighbors help a quadriplegic Maryland veteran and his wife when their home goes up in flames.


text:
Drake Changed the Lyrics of 'Madonna' to Include Rihanna's Name Instead
The reason why is anyone's guess.
DC Comics Doesn't Think Rihanna Should Name Her Magazine 'Robyn'
Too close to Batman's sidekick.
Rihanna Performs 'American Oxygen' & 'Better Have My Money' on 'SNL': Watch
To send off Saturday Night Live's 40th season in style, the show brought out the big guns in Louis C.K. and Rihanna.
Rihanna Is Suddenly Louis C.K.'s Girlfriend in 'SNL' Promos: Watch
She's not so sure.
Rihanna's 'Money' Remixed & Turned Dancefloor-Ready By Diplo, Grandtheft: Listen
The original's menacing, trap-flavored rhythm has been retooled with a turned-up and stripped-back beat and dramatic horn blasts.
Rihanna Is the New Face of Dior: See Her Look
She's the first woman of color to hold the position.
The 11 Biggest Pop Duets of the Last Decade
We compiled a list of the flashiest, most important, most entertaining duets of the last decade in pop music.
Jimmy Kimmel Lampoons Rihanna's Met Gala Dress with the New Rihanket: Watch
Rihanna's dress was a custom couture piece, sewn by one woman over the past year, that will not be available in stores.
Kylie Jenner Basically Wore Her Underwear To The Met After-Party [PHOTOS]
Kylie Jenner didn't get a coveted invite to the Met Gala yesterday, but she definitely made the most out of the afterparty!
Beyonce, Jennifer Lopez, Rihanna, Kim Kardashian & More Celebs Stun At The Met Gala [PHOTOS]
The annual Met Gala in New York City is a place where celebrities can truly have some fun with fashion!


text:
Veterans Contracting Group, Inc.
B-405940: Jan 12, 2012
Additional Materials:
- Full Report:
Ralph O. White
(202) 512-8278
(202) 512-4800
(202) 512-8278
Office of Public Affairs
(202) 512-4800
Veterans Contracting Group, Inc. (VCG), of Mamaroneck, New York, protests the rejection of its bid and the award of a contract to Regiment Construction Corp., of Elizabeth, New Jersey, under invitation for bids (IFB) No. VA-243-11-IB-0284, issued by the Department of Veterans Affairs (VA), to replace a chiller at the VAs New York Harbor Medical Center. VCG contends that the agency improperly rejected its bid.
We sustain the protest.
Jun 30, 2015
- Precise Management, LLC--ReconsiderationB-410912.2
Jun 29, 2015
- Bode Aviation, Inc.B-411265
- Decisive Analytics CorporationB-410950.2,B-410950.3
Jun 26, 2015
- SageCare, Inc.B-411260
- Computer World Services Corporation; CompQSoftB-411216,B-411216.3,B-411216.4,B-411216.5
- WKF Friedman EnterprisesB-411208
Jun 25, 2015
- K-MAR Industries, Inc.B-411262,B-411262.2
Looking for more? Browse all our products here


text:
Synod Celebration Mass - General Registration for Parishes
- Religion & Spirituality
- 600 Main Street, Bridgeport, CT, 06604
Yale LGBT Reunion 2013
Yale GALA (Yale's LGBT Alumni Association) and the Association of Yale Alumni (AYA)
Welcome to the Yale LGBT Reunion Registration Page!
September 20-22, 2013
(Brudner Prize Lecture on September 19)
Note: The registration fee does not include admission to the Benefit Concert on Friday, September 20, 2013. Ticketing for this concert is being handled through a separate registration and must be purchased online via this link: http://yalegalacynthianixon920.eventbrite.com/ (no sales at the door)
Cancellation Policy: To cancel your registration, contact Henry Kwan by email at firstname.lastname@example.com . A cancellation received on or before August 26, 2013 will be refunded the registration fee, less $25. Refund requests received after August 26, 2013, will not be granted. If you do not contact our registration office at the AYA to cancel your registration and do not attend the reunion, your registration fee will be forfeited.
Hotel Room Blocks
Room blocks have been arranged at three New Haven hotels - mention "Yale LGBT Reunion" to get the designated room rate.
We look forward to seeing you at the reunion!
In order to purchase these tickets in installments, you'll need an Eventbrite account. Log in or sign up for a free account to continue.


text:
Madonna at the Super Bowl Totally Looks Like Skyrim Draugr
More funny Sooper Bowl humor over at The Big Game!
Madonna + Marilyn Manson Totally Looks Like Mad Hatter (Johnny Depp)
Bull Frog Totally Looks Like Madonna
Red: The Story of One Painter's Grief and Suffering
The Girl With the Fire/Flying Tattoo
Should I Press the Button?
That Quantum May Just Be Baja Blast
All the Best Reactions to Gay Marriage Becoming Legal Nationwide
Okay, Can Somebody Tell the Green Screen Guy to Cover Up ...
Who Are You Trying to Impress?
America Officially Challenges Japan to a Robot Duel
The Devil is in The Details
Pick Your Site Name
Tell us more about it


text:
Freda Lindstedt, 81 - November 05, 2008
Freda May Lindstedt, 81, of Rock Island Table, formerly of Gothenburg, died Sunday, Nov. 2, 2008, at Good Samaritan Hospital in Kearney.
A visitation will be held Thursday, Nov. 6, from 9 a.m.-8 p.m. with family present from 6-8 p.m. at Blase-Strauser Memorial Chapel of Gothenburg.
Services will be held on Friday, Nov. 7, at 10:30 a.m. at the United Methodist Church of Gothenburg with the Revs. Randall Dilts and Larry Viter officiating. Burial will take place at the Gothenburg Cemetery.
Lindstedt was born on Nov. 6, 1926, north of Callaway to Cleveland Ashley and Mattie May (Price) Pitkin. She grew up at Callaway and then when she was 8 years old her family moved to Oregon. Her parents built and ran cabin camps with a dance hall in Oregon for two and one-half years before returning to Callaway.
She attended school in Callaway and Oregon and graduated from Callaway High School in 1945. Throughout her life she mostly resided on Rock Island Table and then moved to the home of her husband's parents until moving to Gothenburg in May of 2008.
On Aug. 18, 1946, she was united in marriage to Aaron Lindstedt at her parent's home in Callaway. To this union, three children were born.
Lindstedt worked as a teacher and as a farmer's wife. She worked side-by-side with her husband in the fields and doing chores. Everyone was welcome at their table and always had to eat something before leaving, according to family members.
?She enjoyed sewing and quilting as well as playing her keyboard along with her husband at nursing homes, for anniversaries or just for fun, said family members.
?Lindstedt was a member of the Rock Island Extension Club.
She was preceded in death by: her parents, Cleveland and Mattie; her husband, Aaron on May 17, 2008; a brother, Charles Pitkin; a sister, Thelma G'Schwind.
Survivors include: her son, Ted (Debbie) Lindstedt of Cozad; her daughters—Jolene (Don) Olson of Arnold and Peggy (Dan) Yancy of Gothenburg; 12 grandchildren and 10 great-grandchildren; two brothers—Ira (Jo) and Tony (Beverly) Pitkin, all of Callaway; sister, Marge (Dean) Headley of Callaway.
Memorials are suggested to the donor's choice.
Online condolences may be sent to the family at www.blase strauser.com.
Arrangements have been placed in the care of Blase-Strauser Memorial Chapel of Gothenburg.
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Pineapple Orange Sauce
22 Oct 2009
Pineapple Orange Sauce is an irresistible side dish recipe. This delicious Pineapple Orange Sauce is something you would never want to miss out on!
|Canned pineapple chunks in juice
|20 Ounce (1 Dole Can)
|Orange juice
|1 , undrained (From 1 Dole Orange)
|Grated orange peel
|1 (From 1 Dole Orange)
|1 Tablespoon
|1 Tablespoon
|Ground ginger
|1 Teaspoon
Combine pineapple with juice, 1/2 cup orange juice and 1 teaspoon orange peel with remaining ingredients in saucepan.
Cook and stir until sauce boils and thickens.
Cool to room temperature.
Use sauce over frozen yogurt, pancakes or waffles.
Recipe Summary
Course:Side Dish, Fruit Dessert
Rate It
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Pineapple Orange Sauce Recipe


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Driving through Ngorongoro Crater, Tanzania, the sheer density of the animals is truly incredible. There are so many large animals that some of the smaller animals take a back seat at first until you start becoming acclimated to the place. Then, it's the combination of animals that becomes awe inspiring. When I saw these crested crane's it was a total surprise! On the … [Read more...]
The Wildebeest Migration: A Photo Essay
After photographing at Tarangire National Park, Ngorongoro Crater, and Serengeti National Park, the final stop on my African photo safari was the Mara River, near the border between Tanzania and Kenya. Here I watched a natural spectacle like no other: the annual wildebeest migration when wildebeest (along with zebra, gazelle and eland) cross the river in the hundreds of … [Read more...]
The Dancing Egret at Salton Sea, California
There are endless photo opportunities at the Salton Sea, California, and I never tire of watching the comings and goings of the birds. A stop on the pacific flyway, all sorts of birds come to rest and eat here. Although quite common, one of my favourites is the Great Egret, for it's grace. I love to just find myself a comfortable place to sit with a good view, be … [Read more...]
Muddy Elephants in Serengeti National Park
In case you missed my first post about Serengeti National Park, you can read it here. It's all about the central part of the Serengeti and the endless grassy plains that made an excellent backdrop for some minimalist wildlife images. The northern part of the Serengeti is more woodsy, so you don't get the same type of images there, but it has it's own charms. We stayed … [Read more...]
Lions on Kopjes in Serengeti National Park
The Serengeti is a vast grassland where you'll occasionally find small outcroppings of granite, like rocky islands in a sea of grass. They call these rocks kopjes (pronounced ko-pee). This is where the lions find safety from grassfires, shelter under the trees, and vantage points for hunting -- and where photographers can find scenes like no other place. If you've … [Read more...]
Nesting Cormorants on Mitlenatch Island
Looking at my marine chart for the area around Campbell River, BC, I noticed a small island that is marked as a provincial park: Mitlenatch Island Nature Provincial Park. So without any further information than what was on my chart, I headed over there in Snoopy, my little power boat, to see what makes it special. Wasn't I surprised to find a huge colony of nesting … [Read more...]
Baby Elephant Steps
Elephants are such amazing creatures, aren't they? Watching the elephants was my favourite thing to do during my photo safari in Tanzania. I think if I went back I would spend all my time in one place and get to know an elephant family. The mothers are so protective of their babies! I guess all mothers are like that, but the elephant mothers are always touching the babies … [Read more...]
Seagulls and Salmon in Campbell River, BC
Some birds just get all the attention. Everyone loves the spoonbill with all their character, the colourful flamingos, the regal eagles, the elegant egrets and herons. Even the odd and somewhat ugly woodstork gets respect. But what about the lowly seagull? Are they so common as to be uninteresting? Not to me. Especially when it's time for a salmon feast! In Campbell … [Read more...]


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text: Cancer Cell International - Latest Articles http://www.cancerci.com The latest research articles published by Cancer Cell International 2015-06-27T00:00:00Z Stromal-epithelial responses to fractionated radiotherapy in a breast cancer microenvironment Background: The stromal-epithelial-cell interactions that are responsible for directing normal breast-tissue development and maintenance play a central role in the progression of breast cancer. In the present study, we continued our development of three-dimensional (3-D) cell co-cultures used to study cancerous mammary cell responses to fractionated radiotherapy. In particular, we focused on the role of the reactive stroma in determining the therapeutic ratio for post-surgical treatment. Methods: Cancerous human mammary epithelial cells (MRC-7) were cultured in a 3-D collagen matrix with human fibroblasts (MRC-5) stimulated by various concentrations of transforming growth factor beta 1 (TGF-β1). These culture samples were designed to model the post-lumpectomy mammary stroma in the presence of residual cancer cells. We tracked over time the changes in medium stiffness, fibroblast-cell activation (MRC-5 converted to cancer activated fibroblasts (CAFs)), and proliferation of both cell types under a variety of fractionated radiotherapy protocols. Samples were exposed to 6 MV X-rays from a linear accelerator in daily fraction sizes of 90, 180 and 360 cGy over five days in a manner consistent with irradiation exposure during radiotherapy. Results: We found in fractionation studies with MRC-5 fibroblasts and CAFs that higher doses per fraction may be more effective early on in deactivating cancer-harboring cellular environments. Higher-dose fraction schemes inhibit contractility in CAFs and prevent differentiation of fibroblasts, thereby metabolically uncoupling tumor cells from their surrounding stroma. However, higher dose fraction appears to increase ECM stiffening. Conclusions: The findings suggest that dose escalation to the region with residual disease can deactivate the reactive stroma, thus minimizing the cancer promoting features of the cellular environment. Large-fraction irradiation may be used to sterilize residual tumor cells and inhibit activation of intracellular transduction pathways that are promoted during the post-surgical wound-healing period. The higher dose fractions may slow wound healing and increase ECM stiffening that could stimulate proliferation of surviving cancer cells. http://www.cancerci.com/content/15/1/67 Muqeem Qayyum Jin Kwak Michael Insana Cancer Cell International 2015, null:67 2015-06-27T00:00:00Z doi:10.1186/s12935-015-0218-9 /content/figures/s12935-015-0218-9-toc.gif Cancer Cell International 1475-2867 ${item.volume} 67 2015-06-27T00:00:00Z XML Retraction: Hypericin-mediated photodynamic therapy induces apoptosis of myoloma SP2/0 cells depended on caspase activity in vitro No description available http://www.cancerci.com/content/15/1/66 Junping Zhang Linxiang Shao Chunlin Wu Hongfei Lu Ruian Xu Cancer Cell International 2015, null:66 2015-06-24T00:00:00Z doi:10.1186/s12935-015-0199-8 /content/figures/s12935-015-0199-8-toc.gif Cancer Cell International 1475-2867 ${item.volume} 66 2015-06-24T00:00:00Z XML The dual PI3K/mTOR inhibitor NVP-BEZ235 inhibits proliferation and induces apoptosis of burkitt lymphoma cells Background: Phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway is a therapy target of cancer. We aimed to confirm the effect of dual PI3K/mTOR inhibitor NVP-BEZ235 on cell proliferation and apoptosis in Burkitt lymphoma (BL) cells. Methods: Two human BL cell lines, CA46 and RAJI were used in this study. The proliferation of BL cells was detected by manganese tricarbonyl transfer (MTT) assay. Cell cycle and apoptosis assay were examined by flow cytometric analysis. The phosphorylation levels of AKT (Thr308), AKT (Ser473), and RPS6 were evaluated by western blot analysis. Results: NVP-BEZ235 significantly inhibited the proliferation of BL cells (CA46 and RAJI) and the inhibition effect was time and dose-dependent. Cell cycle analysis indicated that the cells (CA46 and RAJI) were mostly arrested in G1/G0 phase. Cell apoptosis assay showed that the late apoptotic cells were significantly increased after 72 h treatment by 100 nmol/L of NVP-BEZ235. In addition, results also found that NVP-BEZ235 reduced the phosphorylation levels of AKT (Thr308), AKT (Ser473), and PRS6 in BL cells (CA46 and RAJI). Moreover, this inhibition effect on phosphorylation was dose-dependent. Conclusions: NVP-BEZ235 effectively inhibited cell proliferation by G0/G1 cell-cycle arrest and induced apoptosis through deregulating PI3K/Akt/mTOR pathway in BL cells. http://www.cancerci.com/content/15/1/65 Chuntuan Li Pengliang Xin Huifang Xiao Yan Zheng Yuanling Huang Xiongpeng Zhu Cancer Cell International 2015, null:65 2015-06-24T00:00:00Z doi:10.1186/s12935-015-0213-1 /content/figures/s12935-015-0213-1-toc.gif Cancer Cell International 1475-2867 ${item.volume} 65 2015-06-24T00:00:00Z XML Only one health, and so many omics The development of new approaches based on wide profiling methods in studying biological and medical systems is bringing large amounts of data on a daily basis.The causes of complex diseases have been directed to the genome examination bringing formidable knowledge. We can study genome, but also proteome, exome, transcriptome, epigenome, metabolome, and newcomers too such as microbiome, connectome and exposome. The title of this editorial is paraphrasing the famous saying of Victor Schlichter from Buenos Aires children hospital in Argentina who said "How unfair! Only one health, and so many diseases". Today there is indeed a whole lot of omics. We think that we are lucky to have all the omics possible, but we also wanted to stress the importance of future holistic approach in integrating the knowledge omics has rewarded us. http://www.cancerci.com/content/15/1/64 Nives Pe¿ina-¿laus Marko Pe¿ina Cancer Cell International 2015, null:64 2015-06-23T00:00:00Z doi:10.1186/s12935-015-0212-2 /content/figures/s12935-015-0212-2-toc.gif Cancer Cell International 1475-2867 ${item.volume} 64 2015-06-23T00:00:00Z XML Increased expression of Six1 correlates with progression and prognosis of prostate cancer Sineoculis homeobox homolog 1 (Six1), normally a developmentally restricted transcriptional regulator, is frequently dysregulated in mutiple cancers. Increasing evidences show that overexpression of Six1 plays a key role in tumorigenesis. However, the Six1 expression status and its relationship with the clinicopathological characteristics in prostate cancer were unclear. In this study, the mRNA and protein levels of Six1 in prostate cancer tissues and normal prostate tissues were evaluated. The clinicopathological significance of Six1 was investigated by immunohistochemistry (IHC) on a prostate cancer tissue microarray. The cut-off score for high expression of Six1 was determined by the receiver-operating characteristic (ROC) analysis. The correlation between Six1 protein expression and clinicopathological characteristics of prostate cancer was analyzed by Chi-square test. Increased expression of Six1 protein was observed in the majority of prostate cancer, compared with their paired adjacent normal prostate tissues. When Six1 high expression percentage was determined to be above 55 % (area under ROC curve = 0.881, P = 0.000), high expression of Six1 was observed in 55.6 % (80/144) of prostate cancer tissues and low expression of Six1 was observed in all normal prostate tissues by IHC. Increased expression of Six1 in patients was correlated with high histological grade (χ2 = 58.651, P = 0.00), advanced clinical stage (χ2 = 57.330, P = 0.000), high Gleason score (χ2 = 63.480, P = 0.000), high primary tumor grade (χ2 = 57.330, P = 0.000) and positive regional lymph node metastasis (χ2 = 19.294, P = 0.000). Furthermore, univariate and multivariate survival analysis suggested that Six1 was an independent prognostic indicator for overall survival (P < 0.05). This study suggests that Six1 could be served as an additional biomarker in identifying prostate cancer patients at risk of tumor progression, might potentially be used for predicting survival outcome of patients with prostate cancer. http://www.cancerci.com/content/15/1/63 Jun Zeng Rong Shi Cui-xia Cai Xin-rui Liu Yan-bin Song Min Wei Wen-li Ma Cancer Cell International 2015, null:63 2015-06-20T00:00:00Z doi:10.1186/s12935-015-0215-z /content/figures/s12935-015-0215-z-toc.gif Cancer Cell International 1475-2867 ${item.volume} 63 2015-06-20T00:00:00Z PDF Association between underexpression of microrna-203 and clinicopathological significance in hepatocellular carcinoma tissues Background: Although recent studies have shown the utility of miR-203 as a cancer-relevant biomarker, the validated clinical significance of miR-203 in HCC remains obscure. The aim of the present study was to evaluate the relationship between miR-203 expression and clinicopathological features in HCC patients. Methods: MiR-203 expression in 95 formalin-fixed, paraffin embedded (FFPE) HCC tissues and their paired adjacent non-cancerous tissues was evaluated by quantitative reverse transcription polymerase chain reaction (qRT-PCR). Simultaneously, expression of miR-203 and its correlation with a variety of clinicopathological parameters and patient recurrence was analyzed. Results: The relative level of miR-203 was 1.1651 ± 0.70378 in HCC tissues, significantly lower than its expression in the corresponding adjacent non-cancerous liver tissues (2.2408 ± 0.75351, P < 0.001). The area under curve (AUC) of low miR-203 expression to diagnose HCC was 0.85 (95 % CI: 0.796 ~ 0.904, P = 0.027) at a cut-off value 1.99 evaluated by the median expression of miR-203 in all tissues, including HCC and normal liver tissues. Expression of miR-203 was negatively correlated to metastasis (r = −0.254, P = 0.013), clinical tumor nodes metastasis (TNM) stage (r = −0.300, P = 0.003), nm23 expression (r = −0.292, P = 0.004), p21 expression (r = −0.223, P = 0.030), microvessel density (MVD)(r = −0.206, P = 0.045) and was positively correlated to cirrhosis (r = 0.487, P < 0.001). Additionally, the recurrent time of lower miR-203 expression group was 57.949 ± 4.184 months, slightly longer than that in the high expression group (54.682 ± 2.591 months), however, no significant difference was noted (Chi-square = 0.206, P = 0.650). Conclusions: MiR-203 plays a vital role in the carcinogenesis and progression of HCC, which makes itself as a predictor for the deterioration of HCC. Furthermore, miR-203 may become a new target for molecular therapy in HCC. http://www.cancerci.com/content/15/1/62 Yongru Liu Fanghui Ren Minhua Rong Yihuan Luo Yiwu Dang Gang Chen Cancer Cell International 2015, null:62 2015-06-18T00:00:00Z doi:10.1186/s12935-015-0214-0 /content/figures/s12935-015-0214-0-toc.gif Cancer Cell International 1475-2867 ${item.volume} 62 2015-06-18T00:00:00Z XML MicroRNA-24 inhibits growth, induces apoptosis, and reverses radioresistance in laryngeal squamous cell carcinoma by targeting X-linked inhibitor of apoptosis protein Background: Increasing evidence indicates that dysregulation of microRNAs is involved in tumor progression and development. The aim of this study was to investigate the expression of microRNA-24 (miR-24) and its function in laryngeal squamous cell carcinoma (LSCC). Methods: Quantitative RT-PCR (qRT-PCR) was used to detect miR-24 expression in LSCC cell lines and tissue samples. MTT, colony formation, and flow cytometry was performed to analyze the effects of miR-24 expression on growth, apoptosis, and radiosensitivity of LSCC cells. Dual-luciferase reporter assays were performed to examine regulation of putative miR-24 targets. Expression of X-linked inhibitor of apoptosis protein (XIAP) mRNA and protein, cleaved or total caspase-3, and cleaved or total PARP protein were detected by qRT-PCR and western blotting assays, respectively. Results: miR-24 expression levels in LSCC cell lines or tissue were significantly lower than in a normal human keratinocyte cell line or adjacent normal tissues. Functional analyses indicated that re-expression of miR-24 inhibits growth, reduces colony formation, and enhances apoptosis in LSCC cells. In addition, miR-24 upregulation increases LSCC sensitivity to irradiation by enhancing irradiation-induced apoptosis, and luciferase activity indicated that miR-24 binds to the 3′-untranslated region (3′-UTR) of XIAP mRNA. Upregulation of miR-24 inhibits XIAP protein expression in LSCC cells, and silencing of XIAP mimics the effects of miR-24 upregulation on LSCC cells. In addition, XIAP mRNA expression significantly increases in LSCC tissues and is inversely correlated with miR-24 expression. Conclusions: Our data suggest that miR-24 inhibits growth, increases apoptosis, and enhances radiosensitivity in LSCC cells by targeting XIAP. Therefore, miR-24 may be a potential molecular target for the treatment of human LSCC. http://www.cancerci.com/content/15/1/61 Li Xu Zhifeng Chen Fei Xue Wei Chen Ruina Ma Shiyin Cheng Pengcheng Cui Cancer Cell International 2015, null:61 2015-06-17T00:00:00Z doi:10.1186/s12935-015-0217-x /content/figures/s12935-015-0217-x-toc.gif Cancer Cell International 1475-2867 ${item.volume} 61 2015-06-17T00:00:00Z XML Pathological features of transplanted tumor established by CD133 positive TJ905 glioblastoma stem-like cells Background: This study is to explore the pathological features of transplanted tumor established by CD133 positive TJ905 glioblastoma stem-like cells. Methods: CD133 positive TJ905 glioma cells were separated by immunomagnetic beads to isolate glioma stem-like cells. TJ905 cells and stem-like cells were inoculated subcutaneously into the mice to establish model of transplanted tumor, respectively. Mice growing condition and behavior were observed. HE staining assay, immunohistochemical assay for GFAP, Ki-67 and Olig-2, and CD34 marked microvascular density (MVD) test were performed. Results: The growing condition and behavior of mice in TJ905 stem cell group was more exaggerated and the models showed stronger malignant features pathologically than that in TJ905 cell group. Glial fibrillary acidic protein (GFAP) in TJ905 cell and stem-like cell group showed the transplanted tumor originated from astrocytes. Expression of Ki-67 and oligodendrocyte transcription factor-2 (Olig-2) in TJ905 stem cells was higher notably and CD34 expression in stem cell group was significantly higher than that in the other two groups. Conclusions: Pathological features of transplanted tumor established by CD133 positive glioblastoma stem-like cells show more malignant. Use of TJ905 stem cells to establish transplanted tumor model in nude mice is excellent for glioma research. http://www.cancerci.com/content/15/1/60 Feng Jin Ran Zhang Song Feng Chuan-Tao Yuan Ren-Ya Zhang Guang-Kui Han Gen-Hua Li Xi-Zhen Yu Yang Liu Ling-Sheng Kong Shu-Ling Zhang Lei Zhao Cancer Cell International 2015, null:60 2015-06-13T00:00:00Z doi:10.1186/s12935-015-0208-y /content/figures/s12935-015-0208-y-toc.gif Cancer Cell International 1475-2867 ${item.volume} 60 2015-06-13T00:00:00Z XML Effect of Matrine on HPAC cell migration by down-regulating the expression of MT1-MMP via Wnt signaling AimThis study sought to explore the exact mechanism of Matrine inhibited migration and invasion of human pancreatic cancer cells. Methods: HPAC or Capan-1 cells were cultured in completed RPMI-1640 medium, contained with 50 μg/ml Matrine or 0.05 μg/ml docetaxel, respectively. Cell viability was evaluated by spectrophotometric analysis using MTT assay. Wound healing assay and transwell approach were used to detect the effects of Matrine on HPAC cell migration and invasion. Western Blot and RT-PCR were performed to detect the expressions of MT1-MMP, Wnt and β-Catenin. CHIP assay was used to detect whether the MT1-MMP transcription activity correlated with Wnt signaling pathway. Results: MTT results indicated that cell proliferration was inhibited by Matrine at a range of concentrations, especially at high dose. We further found that Matrine treatment significantly induced cell migration and invasion decreased. Interestingly, the expression of MT1-MMP decreased evidently upon Matrine treatment, paralleled with the expressions of Wnt and β-Catenin detected by Western Blot and RT-PCR assay. Further analysis of MT1-MMP transcription activity revealed that Matrine reduced the expression of MT1-MMP mediated by Wnt signaling pathway. Conclusion: Matrine play a vital role in inhibiting HPAC cellular migration and invasion through down-regulating the expression of MT1-MMP via Wnt signaling pathway. http://www.cancerci.com/content/15/1/59 Yongchao Ma Fazhang Zou Junping Xiong Wei Wan Li Yin Xianjia Li Zhanyu Bei Lei Yuan Song Meng Jianguo Wang Guohua Song Cancer Cell International 2015, null:59 2015-06-11T12:00:00Z doi:10.1186/s12935-015-0210-4 /content/figures/s12935-015-0210-4-toc.gif Cancer Cell International 1475-2867 ${item.volume} 59 2015-06-11T12:00:00Z XML <it>RB</it> mutation and RAS overexpression induce resistance to NK cell-mediated cytotoxicity in glioma cells Several theories aim to explain the malignant transformation of cells, including the mutation of tumor suppressors and proto-oncogenes. Deletion of Rb (a tumor suppressor), overexpression of mutated Ras (a proto-oncogene), or both, are sufficient for in vitro gliomagenesis, and these genetic traits are associated with their proliferative capacity. An emerging hallmark of cancer is the ability of tumor cells to evade the immune system. Whether specific mutations are related with this, remains to be analyzed. To address this issue, three transformed glioma cell lines were obtained (Rb−/−, RasV12, and Rb−/−/RasV12) by in vitro retroviral transformation of astrocytes, as previously reported. In addition, RasV12 and Rb−/−/RasV12 transformed cells were injected into SCID mice and after tumor growth two stable glioma cell lines were derived. All these cells were characterized in terms of Rb and Ras gene expression, morphology, proliferative capacity, expression of MHC I, Rae1δ, and Rae1αβγδε, mult1, H60a, H60b, H60c, as ligands for NK cell receptors, and their susceptibility to NK cell-mediated cytotoxicity. Our results show that transformation of astrocytes (Rb loss, Ras overexpression, or both) induced phenotypical and functional changes associated with resistance to NK cell-mediated cytotoxicity. Moreover, the transfer of cell lines of transformed astrocytes into SCID mice increased resistance to NK cell-mediated cytotoxicity, thus suggesting that specific changes in a tumor suppressor (Rb) and a proto-oncogene (Ras) are enough to confer resistance to NK cell-mediated cytotoxicity in glioma cells and therefore provide some insight into the ability of tumor cells to evade immune responses. http://www.cancerci.com/content/15/1/57 Mario Orozco-Morales Francisco Sánchez-García Irene Golán-Cancela Norma Hernández-Pedro José Costoya-Puente Verónica de la Cruz Sergio Moreno-Jiménez Julio Sotelo Benjamín Pineda Cancer Cell International 2015, null:57 2015-06-05T12:00:00Z doi:10.1186/s12935-015-0209-x /content/figures/s12935-015-0209-x-toc.gif Cancer Cell International 1475-2867 ${item.volume} 57 2015-06-05T12:00:00Z PDF


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Pure Life Body Lotion Coconut and Vanilla -- 14.9 fl oz
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Coconut oil is an intensive moisturizer and healer that has been used for ages to help treat thirsty or burned skin- blended with natural vanilla extract produces a sensory treat.
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text:
How did three Danes end up being tortured in Lebanon?
What a crisis has done to the people of Greece
Inside Story | 20 Feb 2013 14:07 GMT | Politics, Zimbabwe
The European Union has eased sanctions against Zimbabwe, lifting travel and banking restrictions against a number of members of President Robert Mugabe's Zanu PF party.
"We don't believe that there have been enough reforms in Zimbabwe to allow the easing of sanctions, of restrictive measures by the EU, the reforms that have taken place to date are 'purly cosmetic' types of reforms, arrests and beatings continue in Zimbabwe."- Tiseke Kasambala, the advocacy director of the Africa Division of Human Rights Watch
It is see as a reward for progress over political reforms, and further encouragement for a country preparing for what is hoped to be free and fair elections.
Furthermore, a deal has been reached to lift more sanctions within a month of elections, if the polls are seen as peaceful, transparent and credible.
But Zanu PF has dismissed the measure as 'outrageous and preposterous', arguing that the sanctions are illegal anyway.
And rights groups accuse the EU of putting economic interests ahead of human rights.
They are concerned that freeing up the country's controversial diamond trade, could help fund Robert Mugabe's Zanu PF party and help keep him in power.
Economic hardship and a series of disputed elections have been at the root of much of Zimbabwe's troubles.
Simmering frustrations boiled over in late 2006, as inflation exceeded 1,000 percent. Public demonstrations were quickly banned.
"These sanctions are illegal because the people and institutions who were put on these restrictive list were never afforded procedural rights, they were never given the right to reply to any accusations made against them."
- Tafadzwa Musarara,the chairman of Resources Exploitation Watch
Opposition leader Morgan Tsvangirai was arrested and badly beaten at a rally in March the following year.
Elections were held in March 2008 and Robert Mugabe was declared the winner in polls marred by allegations of ballot-rigging and voter intimidation.
An uneasy power sharing deal was forged in September 2008, with Tsvangirai later sworn in as prime minister.
In June 2009, a review of the constitution began but little progress was made.
But talks resumed this year and now March 16 has been set as the date for a referendum on a new draft constitution. This is seen as a key reform ahead of elections scheduled for July.
So, did Mugabe constitute enough reforms for the EU to ease sanctions? Is the EU putting economic interests ahead of human rights?
Inside Story, with presenter Mike Hanna, discusses with guests: Tafadzwa Musarara, the chairman of Resources Exploitation Watch - an NGO which backs Zanu PF; Tiseke Kasambala, the advocacy director of the Africa Division of Human Rights Watch; and Daniel Hammet, a lecturer on human geography at the University of Sheffield.
"Sanctions are an important part of international diplomacy in trying to tackle events and situations that go against the norms of what we expect as a global society in terms of things like human rights abuses and democracy."
- Daniel Hammet, a human geography lecturer
Source: Al Jazeera

Prime Minister Morgan Tsvangirai is in China. It's a hot topic in Zimbabwe's capital city Harare – at least amongst the politicians.

Tsvangirai is known as being anti-China, accusing the country of ignoring alleged human rights abuses in his country and backing President Mugabe politi
A look at how, even in the digital age, the best way for Zimbabweans to get the news is to pick up the phone.
Politics, Zimbabwe
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Did You Know?
All adults in the group help raise baby Cotton-tops, even brothers and sisters.
Check out What's New at the Zoo every other Thursday during the 5:00pm news on WILX TV. Our Education Curator Dennis will take you on a tour of the zoo in each episode, showing you some of your favorite animals, and sharing fun information you may not have known!
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Tax Tip: Educational tax benefits cheat sheet
By The Tax Institute at H&R Block
Teachers and students are back in the classroom across America, but since some educational tax benefits have expired, they need to be aware that they might not be able to take the credits or deductions they are used to taking. Here's a cheat sheet of which benefits are in effect and those that have expired.
Student-approved and still available
- The Lifetime Learning Credit, up to $2,000, is for taxpayers who pay education expenses, such as tuition and fees, for themselves, their spouses or their dependents. This credit does not require the student to pursue a degree, making this an option for anyone acquiring or improving their job skills through an eligible educational institution. More detailed eligibility requirements relate to a taxpayer's income and filing status.
- The American Opportunity Credit, up to $2,500, is for taxpayers who pay tuition and fees and purchase course materials for themselves, their spouses or their dependents. This credit has more restrictions than the Lifetime Learning Credit, but on the up side, it covers the cost of books and other course materials, which is all important to students facing textbook inflation of 812 percent over the last 30 years.
A taxpayer cannot claim both the Lifetime Learning and the American Opportunity credits for the same student in the same year, so taxpayers will need to study up on which credit better suits their specific situation. Proper planning can maximize educational tax benefits.
School is out on these expired breaks
- The Educator Expense Deduction expired on December 31, 2013. While teachers were able to claim this $250 above-the-line deduction for classroom expenses when filing this year for 2013, they will not be able to claim it for 2014. Although there is no alternate credit or deduction to cover these specific expenses for 2014, educators could explore deducting unreimbursed employee business expenses as an itemized deduction if their miscellaneous expenses exceed 2 percent of their income.
- Likewise, the tuition and fees deduction expired on December 31, 2013. This $4,000 deduction covered the same expenses as the Lifetime Learning Credit and American Opportunity Credit, so taxpayers might consider using either of those credits in 2014 instead of the tuition and fees deduction.
Teachers and students should monitor H&R Block's newsroom for any changes to the education tax benefits that may occur before tax season begins.News Source : Tax Tip: Educational tax benefits cheat sheet
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NATO Airstrikes Hit Gadhafi's Libya Compound
NATO Airstrikes Hit Gadhafi's Libya Compound
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NATO Airstrikes Hit Gadhafi's Libya Compound
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Hot Gossip
Beyonce Gets Goofy, Swanky in Paris
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By Kat Giantis
To most of the visitors at Euro Disney in Paris on Thursday, she was just another blonde in a Goofy hat and platform stilettos.
But underneath that novelty chapeau was Beyonce, who marked the iTunes release of her anthemic new single, "Run the World (Girls)," by hitting the theme park with her 6-year-old nephew, Daniel (mom is her sister, Solange).
And after a long day of listening to "It's a Small World" and fending off life-sized mice, an A-list pop star likes nothing more than to kick back in comfortable surroundings with her hubby.
For Beyonce and Jay-Z, that means seriously luxurious accommodations.
People says the couple, who recently celebrated their third anniversary, have been holed up in a $20,000-a-night (!) two-story penthouse suite at the Hotel Le Meurice since jetting into town by private jet on Monday.
Among the amenities in their nearly 3,000-square-foot pad: an Italian marble bath and a sweeping view of several City of Light landmarks.
The good news is they can probably write off the cost of the deluxe digs as a business expense. Seems it's a working vacation for Bey and Jay, who are said to be recording a new tune with Kanye West.
"They've set up a studio in another suite and have been working nights on her album," says a source.
And while Beyonce has reportedly refrained from going on her usual designer shopping sprees while in town, she's still taking advantage of Paris in springtime.
The day before hitting the Happiest Place on Earth, she joined her music mogul hubby for an alfresco meal at L'Avenue restaurant, where they shared a toast with friends.
Days earlier, Jay-Z took part in another toast during a celebrity-stuffed dinner party tossed by pal Gwyneth Paltrow, who's out stumping for her new cookbook, "My Father's Daughter."
Jay broke bread with the likes of Cameron Diaz and Alex Rodriguez, Jerry Seinfeld, Michael Stipe and Mario Batali. Also in attendance: Paltrow's husband, Chris Martin, who apparently wasn't all that eager to participate in the promotional chow-down.
According to the New Yorker, the Coldplay frontman arrived at the GOOP-y shindig "looking cranky," and a publicist cautioned, "He doesn't want to talk."
Here's hoping that Martin became social enough to exchange a few words with Jay-Z on the proper way to show support for a famous spouse.
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Prepare your portfolio for divergent policies, rising rates, and slower earnings growth.
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Buying a home is a big financial step. Make sure it's right for you and your budget.
If it's a stock picker's market, S&P Capital IQ offers some candidates for consideration.
Consider cybersecurity, health care technology, energy, and agriculture companies.
Check out In the Money, a new publication for more investing ideas and strategies.
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Ten Connecticut Burgers For National Burger Month
Of course, there are more. But is your fav in here? May is National Burger Month, so we've rounded up some options for you.
Image 1 of 10
The Neighborhood Joint
One of the most popular burgers at Corey's Catsup & Mustard is a red-hot number by the name of Oh Burger, You Devil, with a crushed red pepper-seared patty, jack cheese, jalapeno relish, bacon and sriracha mayonnaise. Despite a lot national exposure, "we're still that [neighborhood] place," says partner Tyler Miller.


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Thai Beef Salad
From EatingWell: September/October 1991, EatingWell Serves Two
The hot-and-sour dressing has an exotic flavor, yet has just a few ingredients.
Makes: 4 servings
Active Time:
Total Time:
Nutrition Profile
Diabetes appropriate | Low calorie | Low cholesterol | Low saturated fat | Heart healthy | Healthy weight | High potassium | Gluten free |View Our Nutrition Guidelines »
- 3 tablespoons fish sauce, or reduced-sodium soy sauce
- 3 tablespoons brown sugar
- 1 head iceberg lettuce, halved, cored and thinly sliced
- 1 tablespoon canola oil, divided
- 3/4 pound sirloin steak, trimmed of fat and thinly sliced
- 3 jalapeno or serrano chili peppers, seeded and minced
- 1 onion, finely chopped
- 1 clove garlic, minced
- 1 orange, peeled and white pith removed, coarsely chopped
- 1/4 cup chopped fresh cilantro
- 2 tablespoons chopped dry-roasted peanuts
- Stir together fish sauce (or soy sauce) and brown sugar in a small bowl. Arrange lettuce on a platter or individual plates.
- Heat 2 teaspoons oil in a large nonstick skillet over medium-high heat until hot but not smoking. Stir-fry beef, in batches, until browned on the outside and still pink inside, about 1 minute per batch. Spoon over the lettuce.
- Add the remaining 1 teaspoon oil to the pan and cook chili peppers, onions and garlic, stirring occaccsionally, until softened, about 1 minute. Add the fish-sauce (or soy-sauce) mixture and bring to a boil, stirring. Remove from the heat and stir in orange and cilantro. Spoon over the lettuce and beef, sprinkle peanuts over top and serve warm.
Per serving: 230 calories; 12 g fat (3 g sat, 5 g mono); 42 mg cholesterol; 6 g carbohydrates; 24 g protein; 2 g fiber; 455 mg sodium; 525 mg potassium.
Carbohydrate Servings: 1/2
Exchanges: 1 fruit, 2 vegetable, 3 lean meat, 1 fat
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Recipe Categories
- Type of Dish
- Main dish, meat
- Salad, main dish
- Ethnic/Regional
- Thai
- Health & Diet Considerations
- Diabetes appropriate
- Low calorie
- Low cholesterol
- Low saturated fat
- Heart healthy
- Healthy weight
- High potassium
- Gluten free
- Ease of Preparation
- Easy
- Total Time
- 45 minutes or less
- Servings
- 4
- Main Ingredient
- Beef
- Preparation/ Technique
- Stir-Fry
- Style/Theme
- Entertaining, casual
- Publication
- EatingWell Serves Two
- September/October 1991


text:
Talk:National Library of Scotland
|This article is of interest to the following WikiProjects:
Addition of new 'See also' link[edit]
Dear all,
This is the first time I've done this, so please forgive me (and if possible advise me) if I've not done this correctly.
One of the Library's major collections is the Bartholomew Archive, the archive of the Edinburgh-based cartographic printer and publisher. It is regarded as one of the most important archives of its kind in the world, and as such I believe it warrants a link to the relevant Wikipedia page in the 'see also' section - the page is Collins Bartholomew. It is my aim to help to improve the Collins Bartholomew page meaning it will, in time, become an even more robust link.
My precedent for this is a similar link to the page on John Murray; the NLS holds this important archive too.
What do you think?
Many thanks, User:Karlalbaker —Preceding undated comment added 10:18, 21 August 2013 (UTC)
Potential COI - disclaimer[edit]
I have just updated the information for the NLS's operating budget in the infobox and have fixed the link to the annual audit (which was broken previously). The information is now correct and up-to-date for 2010/11. However, I work for the NLS as the Wikimedian in Residence. This is a minor edit which can easily be verified.
The working link to the the 2008/9 budget is available here and the 2010/11 audit now linked indicates the more recent operating budget in section 3.2 (for info, the Library also publishes its annual review, report and accounts on its website here). Not sure whether this would be a problem but wanted to post here for clarity in case there were concerns. ACrockford (talk) 19:20, 11 September 2013 (UTC)
My reading of the 'main intent' of COI policy is for editors involved in an institution or business making an edit that is promotional or in some way prejudicial for or against, without adequate WP:RS - to simply edit details of annual reports or details seems to be taking that general understanding of the COI issue too far. It is worth stating as above, but hardly an issue. sats 09:18, 12 September 2013 (UTC)
- Start-Class Libraries articles
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- High-importance Edinburgh articles


text:
Brown University ranked 35th in graduate school rankings for medical research and 57th in primary care, according to the latest annual graduate school rankings from U.S. News & World Report. more
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As we have previously discussed, the Supreme Court held in Stern v. Marshall that Congress did not have the authority under the Constitution to empower bankruptcy judges to decide legal claims that are based entirely on state...more
Now that the hubbub surrounding the Supreme Court's June 26 decision in the consolidated case of Obergefell v. Hodges has begun to level off, employers are wondering how the decision will impact their workplaces. (In case...more
Independence Day—no better time to reflect on the numerous (enumerated and unenumerated) rights protected by our United States Constitution. Thanks to Obergefell v. Hodges, those rights are now more clearly focused. However,...more
On June 26, 2015, the Supreme Court handed down its decision in the landmark case of Obergefell v. Hodges. The Court held that the Fourteenth Amendment to the United States Constitution requires all states to license a...more
Delivering a sharp blow to President Obama's efforts to regulate coal plants, the U.S. Supreme Court invalidated the Environmental Protection Agency's (EPA's) 2012 Mercury and Air Toxics Standards (MATS) rule, finding that...more
Regardless of whether you believe the Supreme Court should have decided the issue, last week's decision on marriage equality has the potential to benefit your business. Because the decision creates a uniform definition of...more
On Monday, the U.S. Supreme Court halted further implementation of a U.S. EPA's regulation limiting mercury and other hazardous air toxic emissions from coal- and oil-fired electric power plants. In a 5-4 decision, the...more
The Mercury and Air Toxics Standards rule ("MATS") for electric utility steam generating units has been reversed and remanded with the Supreme Court's much-anticipated decision in Michigan v. EPA on June 29, 2015. Writing for...more
On June 29, 2015, the U.S. Supreme Court delivered another warning to the Environmental Protection Agency (EPA) against overstepping its statutory authority under the Clean Air Act. In Michigan v. Environmental Protection...more
During the United States Supreme Court's 2014-2015 term, the Court departed from the pro-business reputation it had developed in labor and employment cases. This term, employees prevailed more often than not, including in...more
The status quo stands, to a degree. By a 5-4 vote, the United States Supreme Court has concluded that the federal Fair Housing Act ("FHA") authorizes lawsuits not just for intentional discrimination, but for conduct taken...more
On June 15, 2015, the US Supreme Court ruled that a law firm could not recover fees it incurred in defending its own fee application.
The case involved the copper company ASARCO LLC that filed...more
On June 29, the U.S. Supreme Court held that the Environmental Protection Agency (EPA) was wrong not to consider the cost of compliance when it decided to regulate mercury and other air toxic substances emitted from power...more
In 2013, the Supreme Court, in United States v. Windsor, struck down Section 3 of the Defense of Marriage Act ("DOMA") which defined marriage, for Federal purposes, as between one man and one woman. The Windsor ruling...more
In the aftermath of the Supreme Court's decision supporting the payment of subsidies by the federal government to eligible persons seeking insurance through the federal health insurance exchanges ("Exchanges") under the...more
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text: Is the ICD-10 nightmare going to cease? Whether it does or not shouldn't influence whether are prepared for the possible transition. And even if you've already created a ever budget for it, you still need to develop an action plan, and yes, this action plan can be a bit complex in terms of carrying out the involved tasks.But by following an action plan you can rest assured that you'll be covering all the bases in relation to compliance with the new codes.


text:
The FixturesPRO toolkit is designed to save time and help manage sports in schools.
FixturesPRO caters for all sports and comes complete with a dedicated sports
website to link to your school website.
Information published in your sports website is not an additional overhead
but the natural output from the processes needed to manage sports in your school.
With a FixturesPRO site license for your school, you can create an unlimited
number of sports user accounts, perhaps for all the staff and coaches in your
sports department.
More details
Pricing and how to order
"Team Sheet builder has turned the weekly boring job of rewriting and amending the team sheets into a five minute and fun task."
FixturesPRO Login
Find Your School
Wisbech Grammar School47 North BrinkWISBECHCambridgeshirePE13 1JX
Tel: 01945 583631
School Website
Sports Website
Coach:Mr J Williams
Captain:Brodie Ellis
Coach:Mr A Laybourne
Coach:Mr M. Jarvis
Coach:Dr S Miller
Coach:Mr R. Killick
Coach:Mr A. Laybourne
Coach:Mr M Sansom / Mr T Meyrick
Coach:Mr D Garfoot
Coach:Mr D Hyland
Coach:Mr M Jarvis
Coach:Mr T Claydon


text:
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NYC soda ban struck down: Hooray for big drinks
Now that a State Supreme Court justice has struck down New York City Mayor Michael Bloomberg's ban on sugary drinks larger than 16 ounces, here's a look at some of our favorite supersized beverages.
Long Island and New York City's top photos LI notable deaths Recent LI fires Stunning aerial shots of LI landmarks LI people on the move! Promotions, new jobs Guess who: LI celebrity yearbook pictures Peek into Long Island's most lavish homes 14 things you didn't know about LI's valedictorians 26 surprising relics from WWII LI veterans then and now Meyer Steinberg, LI vet, worked on Manhattan Project LIers lose up to 320 lbs: Dieting secrets revealed