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The median home value in Boling, TX is $55,700.
This is
lower than
the county median home value of $91,900.
The national median home value is $170,100.
The average price of homes sold in Boling, TX is $55,700.
Approximately 63.92% of Boling homes are owned,
compared to 16.48% rented, while
19.6% are vacant.
Boling real estate listings include condos, townhomes, and single family homes for sale.
Commercial properties are also available.
If you see a property you're interested in, contact a Boling real estate agent to arrange a tour today!
Learn more about Boling Real Estate.
This amazing ranch has a beautiful approx. 5000+/- sq. ft. custom estate home on approx. 87 acres, which includes over 1000 citrus, 500 fig & 500 pomegranate trees all within 45 minutes of Houston. This custom home has a circular drive with porte-cochere, 3 car garage, 5 bedrooms and 4 1/2 baths with a lavish master bedroom downstairs and a spacious walk-in closet with an oversize whirlpool in the master bath. 2 barns, 1 w/8 horse stalls
Gorgeous home on 4.8 acres in the historical community of New Gulf. This beautiful colonial styled home features 4 spacious bedrooms, 2.5 baths, formals, 2 verandas and a sunroom with spectacular views of the New Gulf golf course. Don't miss this opportunity to own this beautiful well-built home in the Boling ISD!
Immaculate 3BD/2BA custom built home only 1 year old and sits on an acre of land. The kitchen has black granite counters. The floor is all wood flooring but the bathrooms have tile, very nice home!!
Large home in quiet country subdivision in Boling ISD; beautiful oak trees; spacious yard; covered patio; gazebo; attached 2-car garage; detached 3-car garage. Adjacent two lots also available for sale and listed on MLS under ''Lots''.
Iago area - 17 acres with 1 acre lake, 6 inch irrigation well with submersible pump, completely fenced, improved Bermuda grass, currently grazing Longhorn cattle. Approx 35 miles to Sugarland.
Great cottage style with sleigh roof line. Old World Charm with hardwood floors, glass knobs and pulls, french doors but with modern conveniences. The home sits on 2 acres with cross fencing. Boling School District!! The home is currently rented, please do not enter property without a Realtor.
Raised house on block and beams, 3BR/2BA, MASTER BATH IS UNFINISHED, large den, large dining, office, kitchen has an eat in area, partial porch around 3 sides, chicken house, needs TLC, House sold ''AS IS'', no repairs will be made by seller, access to property is an easement, home does not have a water well, they buy water from neighbor, paying about $40 per month, neighbor is willing to keep selling water, his water well is very close to sellers property line.
Beautiful lot with large trees and cleared grassy 9.622 acres on cul de sac street. 1000 feet +/- from the San Bernard River. No public river access. Water well and electricity on elevated pad site. Property is agriculture exempt with cattle (under $200). There are deer on the property for hunting. Dead end street is more private. Barb wire fence circles the property keeping cattle or horses in. Pond on property is typically filled with water except in drought. Property can flood in heavy rains.
Open concept floor plan featuring 2 bedrooms and 2 full baths. Ideal starter home or retirement home.
Secluded 4.6 Acres w/362 ft Road Frontage in Wild Oaks Estates by FM 442. Property consists of three lots and is covered in Century Old Oak Trees. Close to TX-60, Local Schools, Boling Fire Dept, Lago & Newgulf. Minutes to US-59, TX-36 & Bay City. 30 minutes to Brazos Bend State Park, Rosenberg & Richmond. Quiet country living close to city amenities! No mobile homes!
Real Living The Hatmaker Group
1021 61st Street, Suite 100-B
Galveston, TX 77551
Email Us | Visit our Real Estate Website


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http://blogs.ajc.com/atlanta-falcons-bl ... um=twitter
My disdain for D-Led is approaching PB-like levels with his hate for Terrence Moore.
I guess my real beef is with the AJC in that their top Falcons beat writer would much rather prefer to cover the local college teams than the Falcons.
I can't say I follow the local beat writers for all 32 teams thoroughly, but I do read the Denver Post, Houston Chronicle, Chi Sun-Times, etc. quite a bit because I'm trying to find out what other teams needs are and their off-season plans for The Huddle Report.com. But from everything I've seen, D-Led is by far the worst beat writer for the major publication in an NFL city.
Man I HATE this guy
The year's upcoming draft and the college game can be discussed here.
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Man I HATE this guy
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Corvallis 104.3 FM • Hood River 91.9 FM • Portland 90.7 FM
Linda Olson-Osterlund conducts a discussion with listeners on the use of "pretext" stops and racial profiling by local police. Pretext stops occur when police become suspicious about a car or its occupants, and then use a minor traffic infraction as an excuse to initiate a stop. This controversial law enforcement technique led to the fatal shooting of James Jahar Perez, an unarmed black motorist, killed by a Portland policeman in 2004.
Hosted by Lisa Loving
Today's guests are Larry Collins, Michael Harper, and Furlton Burns from POPA, People of Purpose and Associates. Our topic is mentoring and supporting those with the greatest burdens stacked against them.
This is a very positive organization, providing invaluable resources for families, youth, and re-entry programs for the recently incarcerated. Find out what they're doing in and around YOUR community to make Portland a Better Place to Live.
Callers offered the following additional resources during the course of the show:
Minority Information Outreach
The studies are in and the reports have been issued. The Police and the Justice system in Oregon target and lock up a disproportianate percentage people of color.
Oregon House District 43 is one of the most diverse in the state. It also faces some of the biggest challenges: high unemployment, high rates of police misconduct, high displacement from gentrification.
This week Dave and Jo Ann talked with State Rep. Lew Frederick about what role the state can play in addressing some of these problems.
Today's show, hosted by Tom Becker, featured three interviews on green economics, transnational identies in the United States, and the political import of late '70s British music. Related to that last theme, you will hear through out the show music selected by Denise Morris from The Clash "Guns of Brixton", XTC "Respectable Street" and Selector "Too Much Pressure". For specific segments click the links below, and for the whole show click the play button just under them.
Laurie Mercier talks with Luz María Gordillo about her new book, "Mexican Women and the Other Side of Immigration: Engendering Transnational Ties." Luz Maria looked at migratory patterns between western Mexico and Detroit, and how men and women differently participate in it. She also comments on racism in immigration policy and the problem of equivocating undocumented workers with drug-dealers.
Luz Maria Gordillo is an assistant professor of Women Studies and on the graduate faculty for American Studies at Washington State University.
This week on Voices from the Edge, Jo Ann and Dave ask the question "Are the good guys ahead?" Local progressive may be feeling a bit down over the direction of local and state politics lately. City Hall seems more disconnected than ever from the world in which most Portlanders live. Earlier this week, city council voted 4-1 (Commissioner Fritz abstaining) to put a new bond measure before voters for a new communications system and other equipment for the Fire Bureau. With so many city services taking hits - and at least on other proposed bond measure being put on hold because of the economy - should there have been a community discussion about whether this measure could wait? Oregon's gubernatorial race - "Doc vs.
Portland City Council voted 3-2 this morning to let police unit commanders have a vote in certain cases before the new police review board. Does this make the new board "structurally flawed" or does it increase accountability as commissioners supporting the change claim? Voices from the Edge Hosts Dave Mazza and Jo Ann talk about this new development.
This just in: some members of the Tea Party movement have said racist things in public, and displayed racist slogans and images at public events. This is apparently completely acceptable in conservative circles. What's not acceptable, it seems, is pointing out the public racism when it happens.
A dustup between the NAACP and the Tea Party movement throws the racist streak in modern conservatism into stark, ugly relief. It's the next chapter in a sordid tale that predates our Republic. But the good news? The Tea Party's visible virulence is proof that things are getting better.
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Dermatologist (skin)
34 years of experience
Accepting new patients
34 years of experience
Accepting new patients
Greater Heights
2120 Ashland St
Houston, TX 77008 Phone number & directions
2120 Ashland St
Houston, TX 77008 Phone number & directions
License & Identifications
A medical license is required for a doctor to practice medicine in a particular state. Requirements vary by state but most require, at a minimum, post-graduate training in the doctor's specific specialty. An NPI number is a national identifier unique to an individual health care provider and is managed by the Center for Medicare & Medicaid Services (CMS).
Learn more about Dr. John Morrison:
View the full profile to get information on:
- Qualifications
- What's important to you
View full profile
Patient Reviews
Have you visited Dr. Morrison? Share your experience.
Write a Review
Write a Review
Specialties & Research
Dr. John Morrison, MD is board certified in Dermatology.
- He has special expertise in 5 areas:
- Acne (Acne Vulgaris)
- Acne Rosacea
- Melanoma
- Psoriasis
- Skin Cancer
Education & Awards
Dr. Morrison graduated from University of California at Irvine.
- Spanish
Home > Find a Dermatologist > TX > Houston Dermatologists > Dr. John Morrison, MD
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- Additional Information
- Dr. John Troth Morrison MD is a male Dermatologist, has 34 years of experience and practices in Dermatology.
- Where does Dr. John T. Morrison practice?
- Dr. John Morrison has 2 office locations.
Dr. John Morrison practices Dermatology near Houston, TX.
See Houston Dermatologists.


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U.S. Foreign Policy News
The Military's Invaluable 'Soft' Power
Nov 19, 2013
"At a time when too many see U.S. foreign policy in kinetic terms, like drones or special ops, the 'soft power diplomacy' of disaster relief delivers life-saving help to desperate people, and improves their image of America," writes Jane Harman in The Huffington Post.
IAEA Chief Cites Modest Iran Nuclear Progress; Official Report Due
Nov 15, 2013
Public Policy Scholar Michael Adler interviewed IAEA Chief Yukiya Amano and reports in Breaking Defense that Iran's recent slow down on its nuclear program could signal a readiness to create favorable conditions for a deal with the U.S.
The NSA in Mexico: If You Can't Betray Your Friends, Whom Can You Betray?- The Expert Take
Nov 14, 2013
In this Expert Take, David A. Shirk considers the implications of the NSA wiretapping scandal on the US-Mexico relationship. He argues that the current crisis gives President Obama an opportunity to right America's course, and to rebuild the relationship with Mexico. Both countries should ponder the NSA scandal seriously, and recognize that cooperation is not just contingent upon immediate interests but on longer-term mutual benefits.
America Has Nowhere to Go on Egypt
Nov 12, 2013
There's no doubt that American policy toward Egypt and the political turbulence in the Middle East has lacked direction, writes Aaron David Miller in The New York Times. Yet the Obama administration's approach — working with, not against the military, and essentially giving up on any serious effort on democratic reform — is both logical and necessary.
Security Policies for a Post-Snowden Age
Nov 08, 2013
The hemorrhaging leaks by Edward Snowden has the U.S. government reeling, writes Jane Harman in The Washington Post, but it is time that the U.S. explains what we do—and what we won't do—to rebuild shattered trust between our country and other world leaders.
The Case Against Negotiating With Assad
Oct 31, 2013
"U.S. Secretary of State John Kerry is on a roll," writes Aaron David Miller. But, he cautions, negotiations with Assad would be a bad move.
An Incomplete Democracy
Oct 22, 2013
Pakistan, ruled by the military for half of its 66-year life, has taken steps toward democracy, but the process is far from complete as illustrated by the strength and influence of Pakistan's military. When President Obama meets with Pakistan's new prime minister, Nawaz Sharif, on Wednesday, he should use the occasion to bolster the civilian government's role relative to the military, writes Michael Kugelman in this New York Times op-ed.
Dealing with Iran: Get Ready for a Wild Ride
Sep 26, 2013
The Obama administration's effort to negotiate a deal on the nuclear issue is going to be an unpredictable ride, but any deal will need to acknowledge the politics on both sides, writes Aaron David Miller.
The Carbon Tax: An Idea Whose Time Has Come
Sep 25, 2013
Canada Institute Contributor Omer Aziz discusses the future of Canadian and American energy and what that means for both countries efforts to curb carbon pollution.
For Biden, Mexico's endless allure
Sep 20, 2013
Vice-President Joe Biden visited Mexico on Friday to inaugurate the first High Level Economic Dialogue between the two nations. Duncan Wood and Christopher Wilson write about the importance of the dialogue and the role of the vice president.


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1,500-year-old landfill discovered in USVItags: archaeology, pre-Columbian, St. Thomas, Virgin Islands
Crews renovating a public square in the U.S. Virgin Islands have discovered a 1,500-year-old landfill stuffed with shells, bones and pottery fragments.
Public Works Commissioner Darryl Smalls says a team of specialized archaeologists will arrive soon to further excavate the pre-Columbian site. It is located in the capital of Charlotte Amalie on St. Thomas....
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- Did a historian who said he's a victim of McCarthyism get the story wrong?
- Stephanie Coontz's work on the history of marriage cited by the Supreme Court.
- How Does It Feel To Have One's Work as a Historian Cited by the Supreme Court? Cool. Very Cool. Thank You Very Much.
- NYT History Book Reviews: Who Got Noticed this Week?
- David Hackett Fischer wins $100,000 prize for lifetime achievement in military writing


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baxter international inc (BAX:New York)
Last $69.93 USD
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He had a small role in the movie "Mr. Holland's Opus".
Jay is a playwrite.
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Jack Black
Watch Jimmy Fallon and Jack Black Redo Extreme's 'More Than Words' Video for Some Reason
Did we just witness the origin of rock's hottest new duo, Black Fallon?
Dirty On The 30: Friday, February 7, 2014
Who said goodbye to Jay Leno during his final Tonight Show last night and what is Rihanna's phobia? You won't believe it. Click here for Dirty on the 30.
Jack Black Takes Over Myspace, And Eggnog Loses Its Appeal
This week, [lastfm]Jack Black[/lastfm] hijacked Myspace and turned it into his personal website! Crazy, right? Head over and check out the homepage for a taste (uh, wait) of what's going on. There is an eggnog […]


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Tip: For easier set up, choose a password at least seven characters, one capital and a number.
June 01, 2015
MOTHER EARTH NEWS is the Original Guide to Living Wisely. Launched in 1970, each bimonthly issue of MOTHER EARTH NEWS features practical and money-saving information on cutting energy costs; using renewable energy; organic gardening; green home building and remodeling; fun do-it-yourself projects; and conscientious, self-sufficient lifestyles
Instant Read:PC, Mac
GET THE NEW APP to read offline:iPad| iPhone| Android| Kindle HD/HDX
genre: Computers & Technology
country: United States
language: English


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ASUS Radeon HD 3870 512MB G-DDR4AMD's RV670 has been discussed a lot and it's finally almost here. We check out the ASUS HD Radeon 3870 in fine detail!
Here it is!
The new AMD offering! It's the 55nm DX10.1 HD Radeon 3870 and not the 3870 XT or XTX but just the 3870. The other model to launch is the 3850. In the old naming scheme the 3870 would represent an XT while the new 3850 is a PRO.
We have on hand today the brand new 3870 from ASUS. There are a lot of questions that have to be answered and mainly, how does it perform? Where does it sit on the market? How much is it going to cost? Should you buy it? Are NVIDIA in trouble?
We intend to answer all this and more as we look into the 3870 from ASUS.
PRICING: You can find products similar to this one for sale below.
United States: Find other tech and computer products like this over at Amazon's website.
Australia: Find other tech and computer products like this over at PLE Computer's website.
Canada: Find other tech and computer products like this over at Amazon Canada's website.
- Page 1 [Introduction]
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- Page 4 [Test System Setup and 3DMark05]
- Page 5 [Benchmarks - 3DMark06]
- Page 6 [Benchmarks - Half Life 2 (Episode One HDR)]
- Page 7 [Benchmarks - Prey]
- Page 8 [Benchmarks - F.E.A.R.]
- Page 9 [Benchmarks - Company of Heroes]
- Page 10 [Benchmarks - World in Conflict]
- Page 11 [Benchmarks - Crysis Demo]
- Page 12 [Benchmarks - High Quality AA and AF]
- Page 13 [Benchmarks - 3DMark06 - Vista]
- Page 14 [Benchmarks - Call of Juarez (DX10) - Vista]
- Page 15 [Benchmarks - Lost Planet (DX10) - Vista]
- Page 16 [Benchmarks - Company of Heroes (DX10) - Vista]
- Page 17 [Temperature and Sound Tests]
- Page 18 [Power Consumption Tests]
- Page 19 [Final Thoughts]
Further Reading: Read and find more Video Cards content at our Video Cards reviews, guides and articles index page.
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Patrick O'Connell (poet)
From Wikipedia, the free encyclopedia
Patrick O'Connell (1944–2005) was a Canadian poet.
Born in Winnipeg, Manitoba, he was educated at the University of Manitoba. In 1993, he was the winner of the John Hirsch Award for Most Promising New Writer.
- Hoping for Angels (1990) ISBN 0-88801-151-2
- Falling in Place (1993)ISBN 0-88801-173-3
- The Joy that Cracked the Mountain (1999) ISBN 1-896239-52-8
External links[edit]
|This article about a poet from Canada is a stub. You can help Wikipedia by expanding it.


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Search the collections
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Olive Oliver Collection
Image: Travel Diary – Olive Oliver, 1911
Source: Museum Victoria
In 1911 Miss Olive Oliver, a wealthy 32 year old woman from Melbourne, embarked on a round-the-world tour of the United States of America, Britain and Europe. The extensive journey took her to many grand cities and places of natural beauty. Olive travelled with her father, William Oliver, her brother, William Donald ('Don'), and her friend, Gretta Nicolls.
Throughout the trip, Olive kept a travel diary and collected brochures, postcards, menus, concert programs and maps from the places she visited. Museum Victoria has acquired these items as well as Olive's large wooden sea chest, and together these make up the Olive Oliver collection. The diary is a small, leather-bound paper diary in which Olive wrote of her daily activities from 9 March 1911 to 31 December 1911. As the trip lasted about a year, it is likely that there would have been a second diary covering the months of the trip during 1912 but unfortunately it has not survived.
The diary and colourful ephemera enable Olive's travels of almost a century ago to come to life. Yet more than simply recording the story of one woman's travels, the collection gives insights into early 20th century Australia and the cultural outlook and identity that Australians engaged with at this time. It demonstrates the desire among early and subsequent generations of Australian settlers to return 'home' to Britain and Europe, as well as visit other 'new world' countries, and it highlights the importance placed on gaining a cultural education outside of Australia through the 'grand tour'.
The collection is also a record of an era when the world was opening up to women, especially middle and upper class women, as they were granted new economic and legal rights, and presented with unheralded opportunities for travel and recreation, as well as for work.
Apart from the details of her journey, little is known of Olive except that she returned to Australia, did not marry or have children and died in Melbourne 1961. If anyone has any further information about Olive Oliver, please contact the Discovery Centre at Museum Victoria.
Items per page: 10 50 (showing 81 - 86) 86 items
Leaflet - 'The Niagara Belt Line', New York, U.S.A.,1911
'The Niagara Belt Line' leaflet, issued by the International Railway and Niagara Gorge Railroad in New York, U.S.A. in 1911, provides travel information about the journey around the Nia ...Images: 1
Leaflet - 'King Edward Hotel, Los Angeles', U.S.A., 1910
'King Edward Hotel, Los Angeles' is a leaflet issued by King Edward Hotel in Los Angeles, U.S.A. in 1910. It provides information for hotel guests about the hotel and about Los Angeles. ...Images: 2
Leaflet - 'Santa Catalina Island', California, U.S.A., 1911
'Santa Catalina Island', a leaflet issued by Santa Catalina Island Ticket Office in California, U.S.A. in 1911, provides travel information about Santa Catalina Island. When unfolded, o ...Images: 2
Leaflet - 'Overland Excursions to the East, Burlington Route', Omaha, Nebraska, U.S.A., 19 ...
'Overland Excursions to the East, Burlington Route', a leaflet issued by Burlington Route in Nebraska, U.S.A. in 1911, provides information for east-bound travellers on the Burlington R ...Images: 2
Booklet - 'Santa Catalina Island, Official Guide', Santa Catalina Island, California, U.S. ...
'Santa Catalina Island, Official Guide' is a booklet issued in Santa Catalina Island, California, U.S.A in 1911. It provides a history of, and general information about, the island and ...Images: 1
Booklet - 'Santa Catalina Island, Official Guide', Santa Catalina Island, California, U.S. ...
'Santa Catalina Island, Official Guide' is a booklet issued in Santa Catalina Island, California, U.S.A in 1911. It provides a history of, and general information about, the island and ...Images: 2


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Are you Etsuko Shibata?Claim your profile
Publications (11)78.7 Total impact
Article: 14-3-3 Proteins Play a Role in the Cell Cycle by Shielding Cdt2 from Ubiquitin-Mediated Degradation[Show abstract] [Hide abstract]
ABSTRACT: Cdt2 is the substrate recognition adaptor of CRL4(Cdt2) E3 ubiquitin ligase complex and plays a pivotal role in the cell cycle by mediating the proteasomal degradation of Cdt1 (DNA replication licencing factor), p21 (CDK inhibitor) and Set8 (histone methyl transferase) in S-phase. Cdt2 itself is attenuated by SCF(FbxO11) mediated proteasomal degradation. Here, we report that 14-3-3 adaptor proteins interact with Cdt2 phosphorylated at threonine 464 (T464) and shields it from polyubiquitination and consequent proteasomal degradation. Depletion of 14-3-3 proteins promotes the interaction of FbxO11 with Cdt2. Overexpressing 14-3-3 proteins shields Cdt2 with phospho-mimicking mutation (T464D), but not Cdt2 (T464A), from ubiquitination. Further, the delay of the cell cycle in the G2/M phase and decrease in cell proliferation seen upon depletion of 14-3-3γ is partly due to the accumulation of the CRL4(Cdt2) substrate, Set8 methyl transferase. Therefore, the stabilization of Cdt2 is an important function of 14-3-3 proteins in cell cycle progression.Molecular and Cellular Biology 08/2014; 34(21). DOI:10.1128/MCB.00838-14 · 5.04 Impact Factor
Article: CRL4Cdt2 E3 Ubiquitin Ligase and PCNA Cooperate to Degrade Thymine DNA Glycosylase in S-phase.[Show abstract] [Hide abstract]
ABSTRACT: Thymine DNA Glycosylase (TDG) is an essential enzyme playing multiple roles in base excision repair, transcription regulation and DNA demethylation. TDG mediates the cytotoxicity of anti-cancer chemotherapeutic drug, 5-Fluorouracil (5-FU) by prolonging S-phase, generating DNA strand breaks and inducing DNA damage signalling. During S-phase of the cell cycle TDG is degraded via proteasomal pathway. Here we show that CRL4(Cdt2) E3 ubiquitin ligase promotes ubiquitination and proteasomal degradation of TDG in S-phase in a reaction that is dependent on the interaction of TDG with Proliferating Cell Nuclear Antigen (PCNA). siRNA mediated depletion of PCNA or components of CRL4(Cdt2), specifically Cullin4A/B, or substrate adaptor Cdt2, stabilizes TDG in human cells. Mutations in the PCNA-interacting-peptide (PIP) motif of TDG that disrupt the interaction of TDG with PCNA, or change critical basic residues essential for the action of the PIP-degron, prevent the ubiquitination and degradation of TDG. Thus physical interaction of TDG with PCNA through the PIP-degron is required for targeting TDG to CRL4(Cdt2) E3 ubiquitin ligase complex. Compared to forced expression of wild type TDG, CRL4(Cdt2)- resistant TDG (ΔPIP) slows cell proliferation and slightly increases the toxicity of 5-FU. Thus CRL4(Cdt2) dependent degradation of TDG occurs in S phase because of the requirement for TDG to interact with chromatin-loaded PCNA and this degradation is important for preventing toxicity from excess TDG.Journal of Biological Chemistry 06/2014; DOI:10.1074/jbc.M114.574210 · 4.60 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: After acute DNA damage, the intra-S-phase checkpoint arrests S phase progression by inhibiting origin initiation and fork progression to repair damaged DNA. Cdc25A is targeted for degradation by CRL1beta-TRCP to inhibit origin firing. The mechanism for inhibiting fork progression, however, has not been identified. Here, we show that degradation of p12, the fourth subunit of DNA polymerase delta is critical for inhibiting fork progression. CRL4Cdt2 is an E3 ligase that ubiquitinates and degrades p12 after UV treatment. Cells expressing a stable form of p12 exhibit radioresistant DNA synthesis. DNA fiber assay and alkaline-sucrose gradient assay demonstrate that the impairment of fork progression after DNA damage requires p12 degradation. These results suggest that ubiquitination of p12 through CRL4Cdt2 and subsequent degradation is one mechanism by which the intra-S-phase checkpoint inhibits fork progression.Journal of Biological Chemistry 09/2013; DOI:10.1074/jbc.C113.505586 · 4.60 Impact Factor
Article: Abstract 3380: Overcoming platinum resistance in ovarian cancer using the novel compound MLN4924.Cancer Research 08/2013; 73(8 Supplement):3380-3380. DOI:10.1158/1538-7445.AM2013-3380 · 9.28 Impact Factor
Article: Overcoming Platinum Resistance in Preclinical Models of Ovarian Cancer Using the Neddylation Inhibitor MLN4924[Show abstract] [Hide abstract]
ABSTRACT: The nearly ubiquitous development of chemoresistant disease remains a major obstacle against improving outcomes for ovarian cancer patients. In this investigation we evaluated the preclinical activity of MLN4924, an investigational inhibitor of the NEDD8-activating enzyme, in ovarian cancer cells. Efficacy of MLN4924 both alone and in combination with platinum was assessed. Overall, single agent MLN4924 exhibited moderate activity in ovarian cancer cell lines. However, the combination of MLN4924 with cisplatin or carboplatin produced synergistic effects in SKOV3 and ES2 cells, as well as, in primary ovarian cancer cell lines established from high grade serous, clear cell, and serous borderline ovarian tumors. The efficacy of cisplatin plus MLN4924 was also evident in several in vitro models of platinum resistant ovarian cancer. Mechanistically, the combination of cisplatin and MLN4924 was not associated with DNA re-replication, altered platinum-DNA adduct formation, abrogation of FANCD2 monoubiquitination, or CHK1 phosphorylation. An siRNA screen was used to investigate the contribution of each member of the Cullin RING-Ligase (CRL) family of E3 ubiquitin ligases, the best characterized downstream mediators of MLN4924's biological effects . Cisplatin-induced cytotoxicity was augmented by depletion of CUL3, and antagonized by siCUL1 in both ES2 and SKOV3 ovarian cancer cells. This investigation identifies inhibition of Neddylation as a novel mechanism for overcoming platinum resistance in vitro, and provides a strong rationale for clinical investigations of platinum and MLN4924 combinations in ovarian cancer.Molecular Cancer Therapeutics 08/2013; 12(10). DOI:10.1158/1535-7163.MCT-12-1028 · 6.11 Impact Factor
Article: Deubiquitination of Tip60 by USP7 Determines the Activity of the p53-Dependent Apoptotic Pathway.[Show abstract] [Hide abstract]
ABSTRACT: Tip60 is an essential acetyl transferase required for acetylation of nucleosomal histones and other non-histone proteins. Tip60 acetylates the p53 tumor suppressor at Lysine 120 (K120), a modification essential for p53-dependent induction of PUMA and apoptosis. It is known that Tip60 is turned over in cells by the ubiquitin-proteasome system. However, the deubiquitinase activity for stabilizing Tip60 is unknown. Here we show that USP7 interacts with and deubiquitinates Tip60 both in vitro and in vivo. USP7 deubiquitinase activity is required for the stabilization of Tip60 in order to operate an effective p53-dependent apoptotic pathway in response to genotoxic stress. Inhibiting USP7 with the small molecule inhibitor, P22077 attenuates the p53-dependent apoptotic pathway by destabilizing Tip60. P22077, however, is still cytotoxic and this is partly due to destabilization of Tip60.Molecular and Cellular Biology 06/2013; DOI:10.1128/MCB.00358-13 · 5.04 Impact Factor
Article: CRL1-FBXO11 Promotes Cdt2 Ubiquitylation and Degradation and Regulates Pr-Set7/Set8-Mediated Cellular Migration.[Show abstract] [Hide abstract]
ABSTRACT: The Cul4-Cdt2 (CRL4Cdt2) E3 ubiquitin ligase is a master regulator of cell-cycle progression and genome stability. Despite its central role in the degradation of many cell-cycle regulators, e.g., Cdt1, p21, and Pr-Set7/Set8, little is known about the regulation of its activity. We report that Cdt2 is autoubiquitylated by the CRL4A E3 ubiquitin ligase. Cdt2 is additionally polyubiquitylated and degraded by Cul1-FBXO11 (CRL1FBXO11). CRL1FBXO11-mediated degradation of Cdt2 stabilizes p21 and Set8, and this is important during the response to TGF-β, with the Set8 induction being important for turning off the activation of Smad2. The migration of epithelial cells is also stimulated by CRL1FBXO11-mediated downregulation of Cdt2 and the consequent stabilization of Set8. This is an interesting example of crossregulation between specific Cullin 4 and Cullin 1 E3 ubiquitin ligases and highlights the role of ubiquitylation in regulating cellular responses to TGF-β and the migration of epithelial cells.Molecular cell 03/2013; DOI:10.1016/j.molcel.2013.02.003 · 14.46 Impact Factor
Article: MCM8-9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.[Show abstract] [Hide abstract]
ABSTRACT: The minichromosome maintenance protein homologs MCM8 and MCM9 have previously been implicated in DNA replication elongation and pre-replication complex (pre-RC) formation, respectively. We found that MCM8 and MCM9 physically associate with each other, and MCM8 is required for the stability of MCM9 protein in mammalian cells. Depletion of MCM8 or MCM9 in human cancer cells or loss of function MCM9 mutation in mouse embryo fibroblasts sensitizes cells to the DNA interstrand cross-linking (ICL) agent cisplatin. Consistent with a role in the repair of ICLs by homologous recombination (HR), knockdown of MCM8 or MCM9 significantly reduces HR repair efficiency. Chromatin immunoprecipitation analysis using human DR-GFP cells or Xenopus egg extract demonstrated that MCM8 and MCM9 proteins are rapidly recruited to DNA damage sites and promote RAD51 recruitment. Thus these two metazoan-specific MCM homologs are new components of HR and may represent novel targets for treating cancer in combination with DNA cross-linking agents.Molecular and Cellular Biology 02/2013; DOI:10.1128/MCB.01503-12 · 5.04 Impact Factor
Article: Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.[Show abstract] [Hide abstract]
ABSTRACT: CRL4(Cdt2) is a cullin-based E3 ubiquitin ligase that promotes the ubiquitin-dependent proteolysis of various substrates implicated in the control of cell cycle and various DNA metabolic processes such as DNA replication and repair. Substrates for CRL4(Cdt2) E3 ubiquitin ligase include the replication licensing factor Cdt1 and the cyclin-dependent kinase (Cdk) inhibitor p21. Inhibition of this E3 ligase leads to serious abnormalities of the cell cycle and cell death. The ubiquitin-conjugating enzyme (UBC) involved in this important pathway, however, remains unknown. By a proteomic analysis of Cdt2-associated proteins and an RNA interference-based screening approach, we show that CRL4(Cdt2) utilizes two different UBCs to target different substrates. UBCH8, a member of the UBE2E family of UBCs, ubiquitylates and promotes the degradation of p21, both during the normal cell cycle and in UV-irradiated cells. Importantly, depletion of UBCH8 by small interfering RNA (siRNA) increases p21 protein level, delays entry into S phase of the cell cycle, and suppresses the DNA damage response after UV irradiation. On the other hand, members of the UBE2G family of UBCs (UBE2G1 and UBE2G2) cooperate with CRL4(Cdt2) to polyubiquitylate and degrade Cdt1 postradiation, an activity that is critical for preventing origin licensing in DNA-damaged cells. Finally, we show that UBCH8, but not UBE2G1 or UBE2G2, is required for CRL4(Cdt2)-mediated ubiquitylation and degradation of the histone H4 lysine 20 monomethyltransferase Set8, a previously identified CRL4(Cdt2) substrate, as well as for CRL4(Cdt2)-dependent monoubiquitylation of PCNA in unstressed cells. These findings identify the UBCs required for the activity of CRL4(Cdt2) on multiple substrates and demonstrate that different UBCs are involved in the selective ubiquitylation of different substrates by the same E3 complex.Molecular and Cellular Biology 05/2011; 31(15):3136-45. DOI:10.1128/MCB.05496-11 · 5.04 Impact Factor
Article: CRL4Cdt2 Regulates Cell Proliferation and Histone Gene Expression by Targeting PR-Set7/Set8 for Degradation[Show abstract] [Hide abstract]
ABSTRACT: PR-Set7/Set8 is a cell-cycle-regulated enzyme that monomethylates lysine 20 of histone H4 (H4K20). Set8 and monomethylated H4K20 are virtually undetectable during G1 and S phases of the cell cycle but increase in late S and in G2. We identify CRL4(Cdt2) as the principal E3 ubiquitin ligase responsible for Set8 proteolytic degradation in the S phase of the cell cycle, which requires Set8-PCNA interaction. Inactivation of the CRL4-Cdt2-PCNA-Set8 degradation axis results in (1) DNA damage and the induction of tumor suppressor p53 and p53-transactivated proapoptotic genes, (2) delayed progression through G2 phase of the cell cycle due to activation of the G2/M checkpoint, (3) specific repression of histone gene transcription and depletion of the histone proteins, and (4) repression of E2F1-dependent gene transcription. These results demonstrate a central role of CRL4(Cdt2)-dependent cell-cycle regulation of Set8 for the maintenance of a stable epigenetic state essential for cell viability.Molecular cell 10/2010; 40(1):9-21. DOI:10.1016/j.molcel.2010.09.014 · 14.46 Impact Factor
Article: Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage[Show abstract] [Hide abstract]
ABSTRACT: The role of chromatin-remodeling factors in transcription is well established, but the link between chromatin-remodeling complexes and DNA repair remains unexplored. Human Rvb1 and Rvb2 are highly conserved AAA(+) ATP binding proteins that are part of various chromatin-remodeling complexes, such as Ino80, SNF2-related CBP activator protein (SRCAP), and Tip60/NuA4 complexes, but their molecular function is unclear. The depletion of Rvb1 increases the amount and persistence of phosphorylation on chromatin-associated H2AX after the exposure of cells to UV irradiation or to mitomycin C, cisplatin, camptothecin, or etoposide, without increasing the amount of DNA damage. Tip60 depletion, but not Ino80 or SRCAP depletion, mimics the effect of Rvb1 depletion on H2AX phosphorylation. Rvb1 is required for the histone acetyltransferase (HAT) activity of the Tip60 complex, and histone H4 acetylation is required prior to the dephosphorylation of phospho-H2AX. Thus, Rvb1 is critical for the dephosphorylation of phospho-H2AX due to the role of Rvb1 in maintaining the HAT activity of Tip60/NuA4, implicating the Rvb1-Tip60 complex in the chromatin-remodeling response of cells after DNA damage.Molecular and Cellular Biology 05/2008; 28(8):2690-700. DOI:10.1128/MCB.01983-07 · 5.04 Impact Factor
Top Journals
University of Virginia
Charlottesville, Virginia, United States
- • Department of Biochemistry, Molecular Biology and Genetics
- • Department of Medicine


text:
This idea relates to case number 04266521.
Add Wake on LAN option when you select "On Schedule" in Software Update Policy
创建时间: 14 6 月 2013 | 1 条评论
The Wake on LAN check box is currently only available in the "As soon as possible" section of the Software Update Policy.
We should be ableto use the same in the "On Schedule" section as well. Currently, it does not let you.
I see no logic behind it, as to why we cannot use the weake on LAN with a scheduled software update deployment.
意见 归类至以下社区:


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Activities and events in Maine, July 2015 lists the best things to do in Maine in July, Yarmouth Clam Festival, Maine Lobster Boat Races, Bangor State Fair, and more.
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The Maine Lobster Boat Races 2015 schedule has been announced! From Portland to Winter Harbor you will not want to miss one of the most unique things to do in Maine this summer!
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Fun Maine Easter events for 2015 include Easter Egg Hunts, Photos with the Easter Bunny, Easter Brunch, Sunrise Service, and surprise kid's activities!
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The Fryeburg Fair Maine 2015, a Blue Ribbon Classic, with agricultural exhibits, events, shows, and entertainment is a great place to enjoy fall foliage in Maine.
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Dave Ord, Ben Linfoot, Ian Ogg and Sky Bet's Andy Wootton answer the burning questions following the weekend's racing.
Chris Waller has his eyes set on July Cup glory for Brazen Beau, who is among 17 possibles for Saturday's Group 1 sprint.
John Gosden would not be concerned if Golden Horn was forced into making the running again.
A review of the action from Ayr where Irish trainer-and-jockey combination Adrian Keatley and Sean Corby stole the show.
Jack Hobbs could have his next run in France after the Prix Niel was mentioned as a potential target by John Gosden.
Yarmouth will stage its first competitive action of the year on August 30 rather than the planned date of July 23.
Kingston Hill could miss the rest of the season after suffering a further setback.
Fancy a flutter on the racing? Let Sky Sports News HQ's Alex Hammond mark your card every day.
Chris Wilson is keen on the chances of Temptress at Pontefract - he has a tip in every race.
Chris Hill brings us his weekly round-up of the news from the bloodstock scene and the emergence of another first-season sire.
Golden Horn joined some of the great names of the Turf when winning the Coral-Eclipse at Sandown.
Sky Sports News HQ presenter Alex Hammond looks forward to a super Saturday at Sandown and Haydock.
Richard Fahey has runners at six meetings on Saturday. Find out what he makes of his team's chances up and down the country.
Alex Hammond has an extensive preview of Royal Ascot with her best bets for each day.
Find out why our star columnist Richard Fahey has high hopes for Lathom at Royal Ascot on Tuesday.


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Viewtier enhances build management server
Parabuild, a build management server from Viewtier Systems, now comes with manual builds, RSS-based build status notification and next/previous navigation.
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Description: Viewtier Systems' Parabuild is a build management server that provides daily builds as well as continuous integration builds. The product works with an enterprise's existing build infrastructure and supports numerous build scripting tools, such as nmake, nANT and Maven.
The latest edition, Parabuild 3.0, adds build enhancements such as manual builds, the ability to keep running a build if one step fails and a build results publisher. UI improvements include a build time graph, a display group for watching only broken builds and next/previous navigation in build results. In addition, developers can publish a build's status using an RSS feed and hide change descriptions from anonymous users.
Company site: http://www.viewtier.com/index.htm
Demo download: http://www.viewtier.com/downloads.htm


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Alice in Chains Vocalist William DuVall Recalls Being Detained at Own Home
The singer-guitarist was greeted by police as he pulled into his garage and detained while they tried to determine his identity.
The singer-guitarist was greeted by police as he pulled into his garage and detained while they tried to determine his identity.
Soundgarden's Kim Thayil speaks with 'Loudwire Nights' host Full Metal Jackie about the band's epic 'Echo of Miles' rarities collection.
A couple days off for these two bands resulted in this awesome cover, and one of the best birthdays I've ever had! I was invited to attend this recording at Metro 37 Studios in Rochester Hills a couple years ago, and would like to revisit it with you since Sean Danielsen from Smile Empty Soul is performing acoustically at The Machine Shop tonight!
Alice in Chains have unveiled their 'Phantom Limb' video, plus much more, via a new BitTorrent Bundle.
Keeping up with all the new hard rock and metal album releases can be a daunting task. We've made it easier for you, collecting all of the releases for 2014 in one place. Current and upcoming releases are at the top of the list, and you can scroll down to check out what has already come out this year.
Alternative rock act Days of the New seem to have unfortunately fallen apart just months after reuniting for a summer 2014 tour.
Are you angry enough to own this piece of music history?
Bush have announced they will release their sixth album, 'Man on the Run,' via Zuma Rock Records on Oct. 21.
Rick Parashar, who produced Pearl Jam's 'Ten' and other notable albums, has passed away at the age of 50.
Alice in Chains drummer Sean Kinney spoke about how streaming services such as Spotify and Pandora are "a f---ing ripoff" for musicians.
Soundgarden, Alice in Chains, Nirvana and several others have been covered in the new medley / video for '8-Bit Grunge.'
The lineup for the 2014 Rockstar Energy Drink Uproar Festival tour has been announced and it features Godsmack, Seether, Skillet, Buckcherry and more.


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The Winking Idol
From Wikipedia, the free encyclopedia
|The Winking Idol
Film poster
|Directed by
|Francis Ford
|Written by
|Arthur Henry Gooden
George Morgan
Charles E. van Loan
|William Desmond
Eileen Sedgwick
|Distributed by
|Universal Pictures
Release dates
Running time
|200 minutes
(10 chapters, 20 reels)
|United States
The Winking Idol is a 1926 Universal Pictures silent western motion picture serial, consisting of 10 chapters, starring William Desmond and Eileen Sedgwick.
Directed by Francis Ford, the screenplay was written by Arthur Henry Gooden, George Morgan and Charles E. van Loan.
This serial is considered to be a lost film.[1]
- William Desmond as Dave Ledbetter
- Eileen Sedgwick as Jean Wilson
- Jack Richardson as Crawford Lange
- Grace Cunard as Thora Lange
- Moravana as Komi
- Herbert Sutch as Jim Wilson
- Dorothy Gulliver
- Artie Ortego
- Helen Broneau
- Vanna Carroll
- Syd Saylor (as Les Sailor)
- The Eye Of Evil
- Buzzards' Roost
- Crashing Timbers
- Racing for Love
- The Vanishing Bride
- The Torrent of Terror
- Flames of Fear
- The Fight at the Falls
- In the Danger of Dynamite
- The Lost Lode
See also[edit]
- ^ "The Progressive Silent Film List: The Winking Idol". SilentEra.com. Retrieved 2009-01-03.
External links[edit]
|This 1920s Western film–related article is a stub. You can help Wikipedia by expanding it.
|This article about a silent film is a stub. You can help Wikipedia by expanding it.


text:
- 33 total posts
- 2 reviews
- 31 comments
Reviews by Swimgal44
Happy with my Results - Inverness, IL
My procedure took just a few minutes and I am happy with my results. They use a very thin needle and just keep moving along the facial line until they are done. I did the typical parentheses lines and he even did a couple between my eyes. On your way out they hand you a couple of gel cool... READ MORE
Brow lift healing in progress
First I should probably provide some background. I am 47 years old and ever since I was I college I knew that someday I would get a facelift. At this point I am not ready for a facelift but my eyes were starting to droop so even if I am not "face lift" ready I am ready to start on the small... READ MORE
Recent comments from Swimgal44
Oh boy, I would need to look at my paperwork to see what the technical name was. Yeah I have some long scars, it was so he could look in and see what he was doing. I think I got mixed up on what I called it. It was wavy because it... READ COMMENT
Thanks ;0) READ COMMENT
I was given hydrocodone/acetaminophen combo. I had a killer headache so I was happy to take it. I'd be annoyed if I didn't have something that strong. However, it is my understanding that there are more controls over pain meds as of... READ COMMENT
Wow, you are just drop dead gorgeous. READ COMMENT
I received the link to your story from another real self member, I am so sorry this happened. My sister is a retired nurse and wound care specialist, she worked for a company called KCI, they have a negative pressure therapy wound vac,... READ COMMENT


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USWNT Already Has Some Good News
We're even more excited for tonight's World Cup Final.
It's the World Cup Finals Tonight!
Turn it into a party with these easy snack-and-drink combos.
5 Post-Sun Beauty Picks We Swear By
6 slides
You've had some fun—now it's time to refresh your hair and skin.
Bounce Back with This Pharmacist-Approved Hangover Helper
We've all been there. This fix is quick, easy and effective.
Another Upset At Wimbledon: Defending Champ Heads Home
We didn't see it coming, either.
How To: Dress Up Store-Bought Ice Pops
Just in time for the Fourth of July, this kitchen hack for transforming store-bought ice pops into something extra special will make you the star of the barbecue.


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Book your room at Hotel Universel Montreal
Standard Room, 2 Double BedsMax Occupancy: 4 guests (up to 3 children, 3 infants)
Premier Room, 1 King BedMax Occupancy: 3 guests (up to 2 children, 1 infant)
Room, 2 Double Beds (Prestige)Max Occupancy: 4 guests (up to 3 children, 3 infants)
Superior Room, 1 King BedMax Occupancy: 2 guests (up to 1 child, 1 infant)
Get an overview of this hotelFamily-friendly Montreal hotel in Hochelaga-Maisonneuve, walk to Saputo Stadium
This family-friendly Montreal hotel is located in the business district, within a 15-minute walk of Saputo Stadium, Olympic Stadium, and Montreal Biodome. Montreal Botanical Garden is 0.7 mi (1.2 km) away.
Hotel Features
Along with a restaurant, this smoke-free hotel has an indoor pool and an outdoor pool. Free WiFi in public areas, free self parking, and a free area shuttle are also provided. Additionally, a fitness center, a sauna, and a conference center are onsite.
Room Amenities
All 230 rooms feature comforts like memory foam beds and premium bedding, while conveniences include refrigerators and coffee makers. Free WiFi and room service are standard, as are flat-screen TVs with cable channels.Information missing or incorrect? Tell us!
Hotel Amenities
Hotel Amenities
The hotel offers a restaurant. A computer station is located on site and high-speed wireless Internet access is complimentary. In addition to an indoor pool and an outdoor pool, Hotel Universel Montreal provides a sauna and a fitness center. Event facilities measuring 15000 square feet (1394 square meters) include a conference center, conference space, and meeting rooms. A complimentary area shuttle within 2 km is available for guests. This family-friendly hotel also offers a seasonal outdoor pool, a terrace, and tour/ticket assistance. Onsite self parking is complimentary.
Hotel Universel Montreal is a smoke-free property.
- Free self parking
- Free WiFi
- Restaurant
- Indoor pool
- Outdoor pool
- Outdoor seasonal pool
- Fitness facilities
- Sauna
- Pool umbrellas
- Free area shuttle
- Conference center
- Ski storage
- Breakfast available (surcharge)
- Free RV, bus, truck parking
- Conference space
- Conference space size (feet) - 15000
- Conference space size (meters) - 1394
- Number of meeting rooms - 13
- Meeting rooms 13
- Concierge services
- Dry cleaning/laundry service
- 24-hour front desk
- Computer station
- Tours/ticket assistance
- Multilingual staff
- Terrace
- Gift shops or newsstand
- Porter/bellhop
- Safe-deposit box at front desk
- ATM/banking
- Elevator/lift
- Luggage storage
- Smoke-free property
- Number of buildings/towers - 1
- Number of floors - 7
- Total number of rooms - 230
- Year Built 1985
Family Friendly Amenities
- Free Wi-Fi
- Indoor pool
- Outdoor pool
- Refrigerator
- Area shuttle (complimentary)
- Microwave (on request)
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Free self parking, Free RV, bus, truck parking
Room Amenities
- Free WiFi
- Memory foam mattress
- Room service
- Flat-panel TV
- Cable TV service
- Premium TV channels
- Pay movies
- Refrigerator
- Microwave (on request)
- Premium bedding
- Shower/tub combination
- Coffee/tea maker
- Down comforter
- Cribs/infant beds (surcharge)
- Daily housekeeping
- Free local calls
- Hair dryer
- Free toiletries
- Phone
- Iron/ironing board
- Desk
- Blackout drapes/curtains
- Air conditioning
- Climate control
- Private bathroom
Where to Eat
Cooked-to-order breakfasts are available for a surcharge and are served each morning between 6:30 AM and 10 AM.
Resto Bar Le Toit Rouge - This restaurant serves breakfast, lunch, and dinner.
Room service is available.
Nearby Things to Do
An indoor pool, an outdoor pool, and a seasonal outdoor pool are on site. Other recreational amenities include a sauna and a fitness center.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Surfing/boogie boarding nearby
- Water skiing nearby
- Sailing nearby
- Rafting nearby
- Windsurfing nearby
- Mountain biking nearby
- Hiking/biking trails nearby
- Bicycle rentals nearby
- Scooter/moped rentals nearby
- Ecotours nearby
- Golf lessons available nearby
- Cross-country skiing on site
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
- Accessible path of travel
- Accessible parking
Hotel Policies
Check-in time starts at 3 PM
Check-in time ends at 2 AM
Minimum check-in age is 18
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- Kids stay free! Children under 7 years old stay free when using existing bedding.
- Rollaway/extra beds are available for CAD 10 per night.
- Cribs (infant beds) are available for CAD 10 per night.
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- Minimum Spring Break check-in age is 18 years old.
No pets or service animals allowed
- Fee for cooked-to-order breakfast: CAD 9 per person (approximately)
- Crib (infant bed) fee: CAD 10 per night
- Rollaway bed fee: CAD 10 per night
We should mention
Children 7 years old and younger stay free when occupying the parent or guardian's room, using existing bedding. Some facilities may have restricted access. Guests can contact the property for details using the contact information on the booking confirmation. No pets and no service animals are allowed at this property.


text:
[IMAGE]bentech.jpg[/IMAGE]When bus operators head out on their routes, they are unaware what challenges they may face. As we have read in the headlines, operators have been subjected to verbal abuse, spitting, a thrown soda or, in some cases, even physical violence. Some transit agencies are looking into driver partitions as a way of providing better protection for operators.
Philadelphia-based design and fabrication firm Bentech Inc. has been at the forefront of developing driver partitions. "We've actually worked on driver compartments and assemblies for 15 years," says Robert Benninghoff, Bentech manager of sales & engineering. In 1995, Bentech supplied Siemens with several components for the St. Louis Metro light rail vehicles, including the hinges and the vertical support stanchion for the doors.
"It was kind of an R&D process that gave us a working knowledge of the hinge system that would support glass and panels," Benninghoff says.
The company also worked with San Francisco Muni on its Neoplan buses for driver's door compartments in 1999. "It's a product arena that's gone from hot to cold over the years," Benninghoff says.
Testing Two Designs
The company worked with New Jersey Transit (NJ Transit) on a pilot program that tested two prototypes of driver partition designs for two different buses. "About a year ago, we were invited by [the transit agency] to develop a working driver's compartment system for two different buses," Benninghoff says.
One model that was developed — the hinged-door design — was created for NJ Transit's North American Bus Industries' (NABI) low-floor bus, meets ADA requirements and can be furnished with locking latches. The second model is a sliding-door design, which they developed to equip the agency's Neoplan bus. A large transfer cutter situated close to the driver was accommodated by the sliding design. According to Mike Sosnowsky, Bentech sales engineer, this version can be stowed in an open position as an option. Both designs feature upper and lower portions that can be used for advertising, he says.
The partitions are made with laminated tempered safety glass, which complies with the FMVSS AS2 requirements for impact and scratch resistance. With Bentech's design, the glass doors are rimmed with aluminum extrusions (TH12 Series) designed by the company to conform to the shape of the door. All of the edges are covered, creating a rigid and robust design, he adds. The cost of the drivers' doors will be in the $1,000 to $2,000 range, depending upon the transit authority's final design requirements and the quantity ordered, Benninghoff says.
The MS Series of Driver's Partitions comply with National Highway Traffic Safety Administration's regulation (Z26.1-1996) for driver visibility, via the use of safety glass. The partitions, which are easily installed in the field, can accommodate existing partitions and fare collection systems. "We could retrofit existing product work with the OEM in the development stages to develop a door system," Sosnowsky says.
Materials, Costs, Benefits
Sosnowsky says the benefits of the driver partition products include providing a deterrent for abusive passengers, preventing objects from being thrown at drivers and providing noise reduction to allow the driver to focus on the road. Other benefits from a cost analysis point of view include reduced personal injury claims, reduced traffic accidents and a decrease in insurance premiums, he adds.
Bentech will provide complete engineered design with installation assistance, says Sosnowsky. "I can share solid files with the customer, so that's a complete service. We are offering engineered design, install and support thereafter," he says. The company will design a system that will work with the current configuration of the bus.
Bentech has received orders for five Drivers' Door assemblies for NJ Transit's NABI buses and one prototype door for MTA New York City Transit.
When asked what prompted NJ Transit to look into driver partitions, spokesperson Dan Stessel says, "Like many transit agencies, we are concerned about the safety of our bus operators."
The transit agency specified that the driver partition must cover and protect the operator, with minimal blind spots, and be shatter resistant.
NJ Transit will begin testing the driver partitions on five buses and run these buses for 90 days before determining its next step, Stessel says.
The Flatiron Flyer buses, which were supplied by MCI and can carry 57 passengers each, are specially branded with a unique blue-and-sunrise-orange paint scheme designed by RTD and a U.S. 36 corridor stakeholder group.
The Hadley mirror business will remain in Elkhart, Ind., but will relocate from the Hadley site to its own production facility over the next few months. The management, engineering, customer service, administrative and production personnel of the Hadley mirror business will remain with the business and transition to Safe Fleet.
Each year, more and more people look forward to BusCon as a chance to network, learn about new trends and technology, and gain the tools that are necessary to revitalize the way they tackle their own operations.
The countdown clocks were developed in part to address concerns about the overall accessibility of MTA's Bus Time system, which sends wait-time information to riders via text message, a QR code scan, or over a web site.
The report argues that the city should be pushing for the "gold standard" of BRT. That would include a control station that monitors buses and ensures they come at well-spaced intervals and enclosed stops that shelter customers.
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text:
You can clone with HTTPS or SSH.Download Gist
|1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
I did not found the woocommerce_template_functions.php in my WP + Woocommerce setup. Could you please elaborate where to paste the above mention code? I will be thankful to you. Thanks
I need this very urgently to add an custom text field on the single product page just above the add to cart where customers will add special instruction during add to cart. plz let me know how to use this code. Thanks !
In the current version of WooCommerce, the relevant file to update with this hack is "woocommerce/templates/single-product/add-to-cart/variable.php" (which you can copy under your own theme at "{your_theme}/woocommerce/single-product/add-to-cart/variable.php" in order to override it without the risk of a WooCommerce update blowing away your changes.
At least in the current version, though, this hack is only half the battle: you also have to extend https://github.com/woothemes/woocommerce/blob/master/assets/js/frontend/add-to-cart-variation.js to have it recognize that the
input has been "fulfilled" so that it will show the "Add to Cart" button. The script is only looking at
select elements right now, so this variation will never be fulfilled without updating the JavaScript.
Just compared this script with version 2.0.3 script and it looks different. Seems this script is not updated.
Hi, I'm searching a way to add 2 number input fields in WooC. , validate price based on both values from inputs, and save values on order pages, I've aadded fields to single-product, but i can't set price and save those numbers, can you,please, help me/look at my code?


text:
Parrish, FLUSA
Hometown: Parrish Florida
January 30, 2014
Green is where it's at! Eat green or go home
Yes of 25 years!
I started with Dr. Graham in Marathon Key Fl. Been teaching and living this lifestyle for 25 years. Still working with Dr. D www.foodnsport.com
Vegan/Raw Foods Lifestyle Coach, Speaker, Teacher. Essential Oils Consultant, Massage Therapy and Fitness
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text:
church-tx-valley-view-cross-timber-church's FavoritesBack to church-tx-valley-view-cross-timber-church's channel.
- Family Force 5 - Love Addict (ChristianRemix.com)No God, no peace. Know God, know peace.christianmusicremix2008-03-17T00:00:0059,316 views00:03:09
- Switchfoot - We Are One TonightYet another great music video by Switchfoot.littlefreakyman2008-03-17T00:00:0027,228 views00:03:46
- Switchfoot - OH! GravityThe latest music video from Switchfoot, "OH! Gravity"littlefreakyman2008-03-17T00:00:0030,147 views00:02:36
- KJ52 - "Life After Death"KJ52dibromaceton2008-03-17T00:00:0027,875 views00:04:39
- Activate - Stellar KartThe song "Activate" by Stellar Kart!tumeg2008-03-17T00:00:0055,103 views00:03:53
- Shine - NewsboysThe song "Shine" by the Newsboys, this is not the official music video!tumeg2008-03-17T00:00:0057,977 views00:03:45
- Carman Sunday School Rocka music videopopulist2008-03-17T00:00:0020,496 views00:04:05
- Frontline - PillarMTV Video Full GOD BLESSgabo12010-10-01T20:59:5333,906 views00:03:25
- Steven Curtis Chapman - DiveSteven Curtis Chapman - Diveobjektivonemusic2008-03-17T00:00:0030,851 views00:03:46
- Strong Tower by Kutless music videochristian rock music videowilfred12008-03-17T00:00:0048,245 views00:03:54
- Newsboys - He Reigns (Official Music Video)Newsboys' music video to He Reigns.michaelscott12008-03-17T00:00:0025,114 views00:04:11
- Toby Mac- GoneMusic video for "Gone" by Christian recording artist Toby Mac.tobymac2008-03-17T00:00:0077,189 views00:03:30
- Toby Mac-Boomin'The official music video for Boomin', from the tobymac website. Please excuse the slight jump near the start. By the way, for all those who have not seen the video but enjoy the song, around 2:40 you will get a special treat.pinelicker2008-03-17T00:00:0044,992 views00:03:33
- Wake Up! Wake Up!Everyday Sunday music viddemetri12010-10-01T22:22:088,640 views00:02:57
- Hilsong - Take It Allgreat song, agree ?juggier2010-10-01T22:23:0413,308 views00:03:40
- Fireflight - UnbreakableFireflight music videoluvinmuzic092010-10-01T22:33:589,881 views00:03:32
No playlists found for this account.


text: Politics Political news from WNPR Sen. Barbara Mikulski, Congress' Longest-Serving Woman, To Retire By Jasmine Garsd • Mar 2, 2015 Updated at 12:15 p.m. ET. Sen. Barbara Mikulski, D-Md., who has served in the Senate and in Congress longer than any other woman, says she will not seek a sixth term in 2016. Mikulski, 78, announced her decision Monday in Baltimore. " 'Do I spend my time raising money, or do I spend my time raising hell?' " she said she asked herself, according to The Associated Press. Rep. Rosa DeLauro Opposes GOP Education Legislation By Diane Orson • Mar 2, 2015 Sage Ross / Creative Commons Last week's Congressional wrangling over Homeland Security funding temporarily ended House debates in Washington on the GOP's version of the Elementary and Secondary Education Act, also known as No Child Left Behind. Republicans would take away much of the federal government's authority over how states and local school districts spend federal education dollars. Some conservative critics say the bill doesn't go far enough in scaling back the federal role in education. Democratic Congresswoman Rosa DeLauro spoke out last week against the GOP version of the bill. Netanyahu: U.S., Israel Agree On No Nukes For Iran, Split On How To Get There By Krishnadev Calamur • Mar 2, 2015 Israeli Prime Minister Benjamin Netanyahu says that while the U.S. and Israel agree that Iran should not get nuclear weapons, they disagree about how to stop the Islamic republic. But, he tells the 2015 American Israel Public Affairs Committee Policy Conference in Washington, reports of a decline in U.S.-Israeli relations are "not only premature, they're just wrong." Netanyahu says his planned speech to Congress on Tuesday is not intended to be a slight to President Obama. "I have great respect for both" Obama and the office that he holds," he says. Quinnipiac, Hamden Dispute Agreement Over Housing Students By Heather Brandon • Mar 2, 2015 Wasted Time R / Creative Commons Quinnipiac University faces a $150-a-day fine, with the Hamden Planning and Zoning Commission accusing it of violating a 2006 housing agreement that led to construction of the York Hill campus. Final Approval Expected For Casino Ethics Ordinance By Paul Tuthill • Mar 2, 2015 The city council in Springfield, Massachusetts is expected to give final approval Monday to an ordinance restricting public officials from obtaining casino jobs. Hartford's Segarra Fumbles the Numbers, and a Challenger Pounces By Jeff Cohen • Feb 28, 2015 Jeff Cohen / WNPR Hartford Mayor Pedro Segarra is boasting about his record in fundraising emails to potential donors, saying the city's "graduation rates have more than doubled since I took office." It sounds good. But it's not true. Gov. Malloy Taps Army Reservist as New Connecticut Veterans Chief By Heather Brandon • Feb 26, 2015 Office of Gov. Dannel Malloy Governor Dannel Malloy is naming a U.S. Army reservist and ethics officer for Pratt and Whitney to oversee Connecticut's Department of Veterans Affairs. Malloy announced the appointment of Lt. Colonel Sean Connolly on Thursday afternoon. FCC Approves Net Neutrality Rules For 'Open Internet' By Bill Chappell • Feb 26, 2015 The Federal Communications Commission approved the policy known as net neutrality by a 3-2 vote at its Thursday meeting, with FCC Chairman Tom Wheeler saying the policy will ensure "that no one — whether government or corporate — should control free open access to the Internet." The Open Internet Order helps to decide an essential question about how the Internet works, requiring service providers to be a neutral gateway instead of handling different types of Internet traffic in different ways — and at different costs. "Today is a red-letter day," Wheeler said Thursday. Denise Merrill Proposes Changes for Connecticut Registrars of Voters By Jeff Cohen • Feb 25, 2015 Chion Wolf / WNPR Secretary of the State Denise Merrill wants to change the way Connecticut runs its elections, having one professional registrar oversee elections in each city and town. Current state law provides for two registrars in every town: one Republican, one Democrat. But Hartford's failure last year to get all of the polls open in time for voting enraged officials across the state. Ben Barnes's Bad Day: Breaking Down Connecticut's New Budget Deficit By Ryan Caron King • Feb 25, 2015 Chion Wolf / WNPR A miscalculation announced by state budget chief Ben Barnes this week has pushed over the state's spending cap by $54.5 million, putting the proposed budget in the red only a few days after it was announced by Governor Dannel Malloy. Obama Administration Intensifies Criticism Of Israel's Netanyahu By Krishnadev Calamur • Feb 25, 2015 Updated at 5:45 p.m. Secretary of State John Kerry sharply criticized Israeli Prime Minister Benjamin Netanyahu's "judgment" on talks with Iran on its nuclear program — the latest Obama administration official wading into the controversy stirred by the Israeli leader's planned talk to Congress on March 3 on the dangers posed by the Islamic republic. Isn't It Time to (Really) Talk About Iraq? By Colin McEnroe • Feb 25, 2015 James McCauley / Creative Commons A couple of weeks ago, I wrote a newspaper column about the Brian Williams debacle, except it really wasn't about that. It's about the way a relatively small story about a lie told by a news anchor seems to be the only national conversation we can have about our role in Iraq. The Wheelhouse Takes on the Budget, and We're Still Talking About Rowland By Catie Talarski & John Dankosky • Feb 25, 2015 creative commons Governor Dannel Malloy announced his two-year budget plan last week, and everything has been a mess ever since. The proposed budget would hurt social services and cause potential layoffs at UCONN, a situation that drew star basketball players to testify at the Capitol. On Tuesday, we learned that a SNAFU with accounting sets Malloy's proposed budget more than $50 million over the state's spending cap for the next fiscal year. That might be more cuts. OPM Secretary Ben Barnes issued a formal (somewhat confusing) apology. Local Casino Ethics Ordinance Nears Final Approval By Paul Tuthill • Feb 24, 2015 The city council in Springfield, Massachusetts is poised to approve a casino ethics ordinance, but the city's mayor has been silent so far on the issue. The Springfield City Council is expected to give final approval at its next regular meeting to an ordinance that would put restrictions on public officials obtaining jobs at the new MGM casino being built in the city. Supporters say it is intended to foster public trust in the municipal decision making surrounding the casino project. Obama Vetoes Keystone XL Pipeline Bill By Krishnadev Calamur • Feb 24, 2015 Updated at 4:04 p.m. ET The White House has notified the Senate that President Obama has, as promised, vetoed congressional legislation to approve the Keystone XL pipeline project. "Through this bill, the United States Congress attempts to circumvent longstanding and proven processes for determining whether or not building and operating a cross-border pipeline serves the national interest," Obama said in the notification to the Senate. VA Secretary Apologizes For Making Special Forces Claim By Bill Chappell • Feb 24, 2015 Updated at 1:05 p.m. ET. The head of Veterans Affairs has apologized for misrepresenting his military record, after telling a man that he had served in the U.S. Special Forces. Secretary Robert McDonald says he made a mistake. The story drew attention late Monday, weeks after McDonald, an Army veteran and West Point graduate, made the claim during a conversation with a homeless man he met during a community outreach effort. NPR's Quil Lawrence reports: Separatists In Ukraine Say They're Pulling Heavy Weapons Back By Bill Chappell • Feb 24, 2015 In a claim that's meeting with skepticism in Kiev, Russian-backed separatists say they've started to withdraw heavy weapons in eastern Ukraine, as required by a recent cease-fire. Ukraine's military says separatist attacks are ongoing. The development comes after Russia's President Vladimir Putin said he thinks a war with Ukraine would be "apocalyptic" — but that the area is now on a path to stability, after the recent Minsk agreement. ISIS Reportedly Abducts Dozens Of Christians In Syria By Bill Chappell • Feb 24, 2015 Extremist fighters from the self-proclaimed Islamic State, or ISIS, have kidnapped "at least" 90 Assyrian Christians in northeastern Syria, according to a monitoring group. The claim emerges from an area recently targeted by coalition attacks. Marijuana Is Now Legal In Alaska, The 3rd U.S. State With Legal Pot By Bill Chappell • Feb 24, 2015 Alaska's voter initiative making marijuana legal takes effect Tuesday, placing Alaska alongside Colorado and Washington as the three U.S. states where recreational marijuana is legal. The new law means people over age 21 can consume small amounts of pot — if they can find it. It's still illegal to sell marijuana. "You can still give people marijuana, but you can't buy it — or even barter for it," Alaska Public Media's Alexandra Gutierrez reports. "So, it's a pretty legally awkward spot. That probably won't stop people from acquiring it, though." Lawmakers Begin Work on Connecticut Budget By Associated Press • Feb 23, 2015 Chion Wolf / WNPR The General Assembly's budget-writing committee is beginning its work on a response to the two-year, nearly $40 billion tax-and-spending proposal offered by Governor Dannel Malloy. The Appropriations Committee was scheduled to hold its first public hearing about the Democratic governor's plan on Tuesday evening. Additional public hearings and budget presentations from state agencies were planned throughout the week. Superstorm Sandy Victims Say FEMA's Role Is Fatally Conflicted By editor • Feb 21, 2015 After Superstorm Sandy in 2012, Kathy Hanlon's life crumbled. Her Long Beach, N.Y., home had no electricity, her family was traumatized and one of her sons was getting sick. On top of that, there was the bureaucratic maze of flood insurance. "I cried many times because I was so angry when I got off the phone with the insurance company," Hanlon says. "It was demeaning. We had to send them things repeatedly. We had to wait for phone calls. We had to wait for people to come visit the house." U.S.: Major Offensive Planned Against ISIS In Mosul This Spring By Bill Chappell • Feb 20, 2015 Looking to take back a city that has high strategic and symbolic value, the Iraqi military will launch an offensive against fighters from the self-proclaimed Islamic State in the coming months, a senior U.S. military official says. NPR's Tom Bowman reports: "A U.S. Central Command official told reporters at the Pentagon that the military operation to retake Mosul, Iraq's second-largest city, will be in the April-May timeframe, and this operation will involve an estimated 20,000-25,000 Iraqi soldiers. British Fighter Jets Escort Russian Bombers Away From Coast Of U.K. By Jackie Northam • Feb 19, 2015 British fighter jets scrambled from their base on Wednesday after two Russian long-range bombers skirted the coast of Cornwall, in the southwest of England. The incident comes one day after British Foreign Secretary Michael Fallon warned about Russia's intentions in Europe. Hartford Stadium Developers Seek Financial Assistance to Lower Apartment Rents By Jeff Cohen • Feb 19, 2015 DoNo Hartford LLC The developers of the new minor league baseball stadium in Hartford are also building apartments around the venue. They're looking for ways to make some of those units accessible to people with lower incomes. Officials held a ceremonial groundbreaking earlier this week for the baseball stadium. Soon, across the street, the work to build the retail, residential, and entertainment project will begin. Gov. Malloy Plans to Transfer 1,500 Judicial Positions to Other Departments By Lucy Nalpathanchil • Feb 19, 2015 Chris Reed/iStock / Thinkstock As part of his $40 billion biennial budget proposal, Governor Dannel Malloy wants to move more than 1,500 positions from the judicial branch's court support services to the Departments of Correction and Children and Families. The proposal is part of the governor's "second chance society" initiative to change the state's drug laws so non-violent offenders have a better chance of re-integrating into society. Reforms include making certain non-violent offenses misdemeanors, and eliminating mandatory minimum sentences for drug possession. Poll Shows Bloom Has Fallen Off Olympic Bid For Most Bostonians By Eyder Peralta • Feb 19, 2015 Just a little more than a month since Boston was chosen to become the next American city to put together an Olympic bid, Bostonians seem to be getting cold feet. A poll commissioned by NPR member station WBUR found that a plurality of Bostonians (46 percent) "oppose the idea of bringing the Olympic Games to the Boston region in 2024." WBUR's Asma Khalid tells our Newscast unit that just 44 percent of those polled support the bid. Gov. Malloy Touts "Tough Choices" Budget By Harriet Jones • Feb 18, 2015 Jessica Hill / Associated Press Governor Dannel Malloy has unveiled his biennial budget, a document aimed at closing yawning gaps projected in state finances in the next two fiscal years. The governor wants to achieve this with a package of spending cuts and a reform of tax codes that will net the state government more revenue. "The budget I present to you is filled with tough choices," the governor told the legislature. "All told, my proposal contains more than $590 million in cuts to the current services budget." Most of those cuts come in the areas of social services and higher education. While there will be no layoffs of state employees, the administration will implement what it termed an "aggressive" hiring freeze, aiming to shrink the workforce by attrition by several hundred positions over two years. Gov. Malloy Proposes Cutting Funds to Bury the Poor By Jeff Cohen • Feb 18, 2015 Stephan Ridgway / Creative Commons Governor Dannel Malloy is proposing paying less to bury the poor. Malloy told legislators in his budget address that balancing the budget means hard choices. "The vast majority of these cuts are choices that, under ideal circumstances, Connecticut would not have to make," he said. Obama Names Joseph Clancy As Secret Service Director By Bill Chappell • Feb 18, 2015 Four months after he was brought back to an agency that was struggling to cope with a series of embarrassing missteps, Joseph Clancy was named the permanent director of the Secret Service on Wednesday. Clancy has been the agency's acting head since the service's director, Julia Pierson, resigned in October. He is the former leader of the Secret Service's Presidential Protective Division. Baker Administration Commits Money To Western Mass. Broadband By Jim Levulis • Feb 18, 2015 Listen Listening... / Massachusetts Governor Charlie Baker, a Republican, is continuing support for a broadband initiative started under former Democratic governor Deval Patrick. The state is releasing $50 million of previously approved capital funding to expand internet connectivity in western Massachusetts. Pages« first ‹ previous … 7 8 9 10 11 12 13 14 15 … next › last »


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Indonesia 2013 - OMBAK PEDAS
A Surfing video by Edouard Delpero - 1,465 views
Stop motion surfing with Arthur Bourbon, Antoine Delpero, Edouard Delpero.. We let you discover our road trip in Indonesia which took place last may 2013.. Which Island ? Which Place ? Let your imagination work ! Surfers: Arthur Bourbon, Antoine & Edouard Delpero Photography: Laurent Gaden
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Lemon Wafers
18 Jul 2010
|1⁄2 Cup (8 tbs), softened
|Powdered sugar
|1⁄4 Cup (4 tbs)
|Lemon peel
|1 Tablespoon, grated
|Lemon extract
|1⁄4 Teaspoon
|1⁄8 Teaspoon, ground
|All purpose flour
|1 Cup (16 tbs)
|1 Cup (16 tbs), chopped
|Powdered sugar
|1 Tablespoon
Cream butter and sugar until fluffy.
Add lemon peel, lemon extract, and ginger.
Add flour and mix well.
Stir In nuts.
Shape dough into balls the size of small walnuts.
Place 2 inches apart on ungreased cookie sheets.
Bake at 325° for 15 to 17 minutes, or until cookies just begin to brown.
While cookies are still warm, roll in powdered sugar
Rate It
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Lemon Wafers Recipe