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Bladder Cancer Center
Having Surgery? Quit Smoking
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Smoking May Raise Risk of Second Cancer
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A Potential New Treatment for Bladder Cancer
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Bladder Cancer
Table of Contents
Your bladder is a hollow organ in the lower abdomen. It stores urine, the liquid waste made by the kidneys.
Your bladder is part of the urinary tract. Urine passes from each kidney into the bladder through a long tube called a ureter. Urine leaves the bladder through a shorter tube (the urethra).
The wall of the bladder has layers of tissue. The inner layer of tissue is also called the lining. As your bladder fills up with urine, the transitional cells on the surface stretch. When you empty your bladder, these cells shrink. The...
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Volkswagen 'Golf Cabriolet' by DDB UK
DDB UK has created a TV campaign to mark the return of Volkswagen's Golf Cabriolet to the car market.
The spot evokes childhood memories of having fun in open-top toy cars, with the Kinks track Days as the soundtrack.
It was written by Mike Crowe, art directed by Rob Messeter and directed by Benito Montorio through Blink Productions.

subset: commoncrawl


text: Calendar Stream Posterboard Stream Month Week Day Agenda Categories Community Concerts February 2014 February 20 (Thursday) Gin & Juice Party @ R.C. McGraw's Feb 20 @ 9:00 pm – 11:00 pm Community All The Hits Z96.3 presents the Gin & Juice Party at R.C. McGraw's, Thursday, February 20th from 9-11PM! It's a BIG TICKET BLOWOUT! Starting at 9, we'll [...] Subscribe to filtered calendar Add to Google


text: No recent wiki edits to this page. Maximilian Thermidor pilots a black and red coloured mid-weight reverse-jointed craft, Unsung. His goal is to succeed and make Rayleonard's former vision a reality. Equal parts romanticist, visionary, and passionate demagogue, he is a complex, if not divided man. He is one of the Original five. He believes that carrying out the former Rayleonard's "Closed Plan" will open the last frontier for mankind...Outer Space. He shares some personality and AC part design (with emphasis on energy weaponry and missiles) to Berlioz in Armored Core 4. It is revealed during "Attack on Arteria Cranium" (on Hard Mode only) that Thermidor is actually Otsdarva, who faked his apparent death when his boosters malfunctioned during a fight with White Glint. Otsdarva then became a double agent for the League, infiltrating ORCA, and betraying the player during the aforementioned mission.


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The Sports Network
DATE & TIME: Monday, November 19, 6 p.m. (et)
FACTS & STATS: Site: Stabler Arena (5,600) -- Bethlehem, Pennsylvania. Television: None. Home Record: Fordham 0-0, Penn 1-1. Away Record: Fordham 0-2, Penn 0-0. Neutral Record: Fordham 0-1, Penn 0-2. Conference Record: Fordham 0-0, Penn 0-0. Series Record: Fordham leads, 6-2.
GAME NOTES: The Fordham Rams continue their search for their inaugural win of the season on Monday when they take on the Penn Quakers in the NIT Season Tip- Off consolation round at Stabler Arena.
Fordham enters its fourth game of the year winless after being handed a 74-58 setback by Robert Morris its last time out. The Rams opened up the season with double-digit losses on the road to Texas State and Pittsburgh. Coach Tom Pecora had endured two losing seasons in both years since joining the program, but there is still plenty of optimism he can bring the success that gave him an average of 19 wins per year at Hofstra before arriving in the Bronx. That turnaround is unlikely to come anytime soon as he will be without his star forward Chris Gaston for the at least the next four weeks.
Penn will also be trying to snap a three-game losing slide after blowing a seven-point lead in the final minute in a two-point loss to its neighborhood rival Drexel Dragons on Saturday. The Quakers had the ball in the closing seconds, but did not get off a shot and fell 61-59. Coach Jerome Allen guided his squad to a five-point win over UMBC in its season opener, but it followed that triumph with back-to-back losses to Delaware and Fairfield in the earlier stages of the NIT Season Tip-Off.
The Quakers and Rams will be playing for the ninth time in history. Fordham holds a 6-2 edge in the all-time series.
Fordham shot 43.9 percent from the field and grabbed 42 rebounds in its season opening loss to Texas State. It has been held under 37 percent shooting from the floor and pulled down 55 total rebounds in the two games since. Gaston's absence will take away averages of 11.3 points and 8.7 rebounds per game from the overall production of the Rams. They will still have their top two leading scorers in junior guard Branden Frazier (14.3 ppg.) and sophomore guard Bryan Smith (13). Frazier is coming off of a stellar performance in which he finished with 21 points and seven assists versus Robert Morris. Smith added 12 points in the same contest, but they will both have to step up their production even further to make up for its depleted front court.
The Quakers are hitting a decent 42.9 percent of their field goals this season, but it was evident they miss the outside shot of Zack Rosen when they converted just 4-of-17 from three-point range versus Drexel. While Penn relied on the backcourt duo of Rosen and Tyler Bernardi heavily on offense last season, Fran Dougherty and Miles Cartwright have stepped up to become the team's new one- two punch. Dougherty averaged just 4.5 points and 4.1 rebounds per game in 2011-2012, but the junior center has raised his averages to 20.5 points and 9.3 boards per contest. Cartwright is adding 17 ppg and a team-best 3.3 apg.
Although Dougherty and Cartwright's statistics are impressive, they would be able to enjoy them if they led to victories. Penn should be able to add another one to the win column with Gaston out and Dougherty dominating in the paint.
Sports Network Predicted Outcome: Penn 64, Fordham 59


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A discovery by tactical otaku research consortium, 2ch, has found that the hit anime of the season, a romantic fantasy adventure by the name "Maoyuu Maou Yuusha", spoils the entire story in the end sequence.
Series make hints at future events or background details in the opening or closing credits on occasion – yet Maoyuu doesn't just give a few details, it retells the story to surprising precision, with every event and turn accounted for. The ED of Maoyuu consists of slides with classic storytelling themes, and accompanying text which was perceived as filler typography added simply for visual effect – yet it turns out it wasn't gibberish after all as an otaku has decoded it into plain English, and it truly tells of what lies ahead.


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List Price: US$3.96
|Free shippingTo UNITED STATES
Ships within 7-10 business days
All packages from DX.com are sent without DX logo or any information indicating DX.com. Due to package variations from suppliers, the product packaging customers receive may be different from the images displayed.
To enable volume discounts on this site, use coupon code: BULKRATE during checkout. You will see a discount applied at the bottom of the shopping cart. Competitive pricing is available. Contact us for details.
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In my Dell Inspiron 540 the only x1 slot was covered by the fan of my graphics card that i added earlier. Since I need the x1 slot for my USB3 card I used this cable to install that USB3 card upsidedown above an empty This... Read more
In my Dell Inspiron 540 the only x1 slot was covered by the fan of my graphics card that i added earlier. Since I need the x1 slot for my... Read more
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Subscribe to Optimist online to stay current on all things APLA!
With "In the Loop," APLA's online advocacy network, you can share your voice with elected leaders and shape fair and effective HIV-related public policy.
APLA is on the ground at the local, state, and federal levels to defend funding and programs that people living with HIV/AIDS depend on.
See your dollars at work — and get insider info on our events and more. Sign up for APLA's online updates now.
Registered? Log in »
Your one-stop center to manage your giving, e-subscriptions, and more. Login to your activity center now!
Joining the APLA family changes lives. Share your story here — and we just might feature you on apla.org!
Join us for a tour of AIDS Project Los Angeles to learn more about the programs and services offered to over 11,000 clients every year.
TEAM TO END AIDS (T2) is APLA's endurance training program. Learn how we can help you cross the finish line while you raise money for the fight to end AIDS.
Collective Effect are socially-conscious doers supporting APLA's mission through education, community service, engaging events and social networking, making a direct impact on our community.
Find expert perspective and fresh insight into the epidemic, along with the latest information on our work.
Sign up for our e-news to get updates on all things APLA.
July 2, 2015
June 26, 2015
June 26, 2015
By Darsha Philps, abclocal.go.com
October 17, 2010
WEST HOLLYWOOD, Calif. (KABC) -- The wet weather Sunday didn't keep thousands of Angelenos from filling West Hollywood streets for the 26th Annual AIDS Walk. The fundraiser spanned 6.2 miles and is expected to reel in nearly $3 million to help treat and care for those living with AIDS and HIV. Since 1985, the event has raised about $66 million for AIDS Project Los Angeles, one of the largest nonprofit AIDS service organizations in the country. Various elected officials as well as celebrities were expected to partake in the walk. Event organizers said they expected a total of approximately 30,000 people to take part in the walk. "When we first started this AIDS thing, we were losing friends left and right and walking is something everybody can do and something I can still do," said Hollywood resident Don Foley, 80, who has participated in all 26 walks since the event's inception. Though many roads in and around West Hollywood will be closed or rerouted for the walk, organizers said all roads should be re-opened during the afternoon. Opening ceremonies kicked off the event around 9 a.m. in West Hollywood Park. From the park, the walk went east on Santa Monica Boulevard, south on La Cienega Boulevard, east on Melrose Avenue, south on La Brea Avenue, west on Beverly Boulevard, and finally north on San Vicente back to the park.
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Williston North Dakota Car Rentals
It's easy to find rental car options in Williston, ND when you let RoadsideAmerica.com help! You can make an online reservation with a Williston, North Dakota rental car agency after you select from a range of rental car companies, vehicle types, and rates. Compare your rental car options in Williston, North Dakota by filling in the form below with your desired dates and other information. Pick the vehicle that's right for you, your passengers and your activities, whether it's a road trip or a business mission.To find Williston, ND car rentals, simply enter your itinerary into the search box below.
Smarter Car RentingHere are car rental tips from the road trip-seasoned editors of RoadsideAmerica.com:
• Many States, One Car:If renting a car for a longer road trip, check with the car rental companies in Williston, North Dakota to see if they have policies about crossing state lines that affect the final rate you pay. May be no effect, but don't assume you can crisscross the globe with unlimited mileage impunity. There may be a GPS tracker in the car!
• Special Requests:Special requests can be noted at the time you make your Williston rental car reservation. Nothing too crazy, though. If you are in need of an infant or toddler car seat, navigation system, ski rack or more, be sure to make note of it when booking online. Keep in mind that requests are not guaranteed and additional fees may apply.
• Under 25?Everyone over 25 assumes you are an awkward and unpredictable risk behind the wheel. Ridiculous, you say, without taking your eyes off the road. But be sure to check with Williston North Dakota car rental companies about their specific policies. Some agencies require the driver to be at least 25 while other rental companies may allow younger drivers to rent for an additional fee. Have more than one driver? Be sure to ask if additional charges apply for more than one person driving the rental car.
Click here to see Williston attractions
Williston Area Attractions
- Mercy Behavioral Health Svc
- Mercy Medical Ctr
- Sloulin Field International Airport (ISN)
The following car rental companies are available in Williston North DakotaClick on the logo or name to see more information.
Avis Rent A Car System, Inc.
Williston Airport
Williston ND US 58801
Williston ND US 58801
If you like the services of a particular car rental company, no problem! We offer a variety of national brand car agencies that operate in Williston. Choose to look at only options from a specific rental car brand, or compare rates and vehicles from others by using the search box above. And remember to enter in your discount or reward number during online check-out when you rent your car in Williston, ND.


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Brought to you by NRHA and the
National Hardware Show®
Click on a product category below to pull up a list of NRHA Vendor Partners with additional product and training information available.
NRHA's product knowledge training
programs for employees are designed
to give store associates the information they need to be productive right from the
start. We offer training programs in core hardware and building materials categories
and it's free to all NRHA members.
April 22, 2013
Bringing a pet into your store is a great conversation-starter for employees and customers. But before your four-legged friend becomes an in-store regular, make sure the animal, store and employees are prepared.
Any retailer thinking of bringing a pet into his store should make sure the pet is comfortable there. It helps if the animal has a small space, such as an office, where it can go to get away from people and any other pets. It's also good to have a place to put the pet if a customer comes in who is allergic or afraid of animals. You should also find out if any employees are allergic to animals and make the necessary accommodations before bringing the animal into the store full time.
You should also keep the animal clean and well-groomed to help with shedding and make sure the animal is properly socialized to handle the flow of people coming in and out of the store each day and trained to not chew on items for sale.
In Category: Management Tips
Related: Management, Operations, Pet
« Back | ^ Back to Top
Featuring independent retailers nationwide, NRHATV on YouTube provides an intimate, inside look at some of our industry's most innovative operations.
Watch Now
See what's going on around the industry, click here to see Who's on Twitter.
Also: @hardwareretail, Store Tweets, Staff Tweets
Fun, behind-the-scenes photos, videos, forums and blogs from the NRHA and Hardware Retailing magazine on Facebook.
Click here to open the digital edition of Hardware Retailing magazine.


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Sony Ericsson teases over see-thru Xperia Pureness phone
Sony Ericsson has revealed some images - but scant info - on a new handset coming soon that boasts a futuristic new design.
The "Xperia Pureness'" design is sort of the opposite of LG's "Crystal" handset with a transparent display, rather than transparent keypad.
We know very little about the device's specs but we are promised more in November when the phone will both be announced, and available.
We will keep you posted.


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San Lorenzo
Teen Killed By Amtrak Train In San Lorenzo Identified
A boy who was fatally struck by an Amtrak train in San Lorenzo on Thursday evening has been identified as 15-year-old Austin Price of Hayward, according to the Alameda County coroner's bureau.
Teen Playing 'Chicken' Fatally Struck By Amtrak Train In San Lorenzo
A 14-year-old boy was fatally struck by an Amtrak train in San Lorenzo on Thursday evening, officials said.
Teen Girl Hurt In San Lorenzo Hit-And-Run Crash
A 16-year-old girl was struck and injured by a hit and run driver in San Lorenzo on Saturday as she walked toward her school, the California Highway Patrol said Sunday.
About The Bay: Dissecting The Differences Between San Leandro, San Lorenzo
Both are Alameda County suburbs, named after saints, border each other, and even each have 10 letters in their names.
Metal Thieves May Have Sparked San Lorenzo Strip Mall Fire
Firefighters extinguished an electrical fire on the roof of a strip mall in San Lorenzo early Tuesday morning, and investigators believe the fire may have been started by thieves attempting to steal copper wiring, a fire spokeswoman said.
Woman Hit By SUV While Crossing San Lorenzo Street
A woman was injured when she was struck by an SUV while crossing a street in San Lorenzo on Wednesday night, according to the California Highway Patrol.
East Bay Retiree Hits $11 Million SuperLotto Jackpot
An East Bay retiree won big in Saturday night's lottery draw, adding $11 million to her retirement fund, California Lottery officials said.
Family Of 5 Escapes Burning San Lorenzo Home
A family of five is lucky to be alive Saturday morning after escaping a dangerous, fast-burning fire at their duplex in San Lorenzo, Alameda County fire officials said.
2 Dead, 7 Hurt In San Lorenzo Minivan Crash
A fatal car crash in San Lorenzo left two people dead at the scene and another seven in area hospitals with injuries ranging from minor to critical, emergency responders said.


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Since 1920, the physicians and staff that compose St. Joseph Health - Humboldt County have been recognized as the best in the region. Continually improving and growing, there are now over 1,400 people who work for SJHS-HC – providing the highest quality of healthcare and always pushing for higher standards in every medical discipline.
Use our online physician search to find the right doctor for you.
Recognized as offering the very best in cancer care and treatment.
We provide a number of classes & events, click here to see them.
2700 Dolbeer Street
Eureka, CA 95501
You can help others by donating to St. Joseph Hospital.
Learn about the many ways to help us at St. Joseph Hospital.
Give the gift of time!Click here to learn more.
Retired physician's assistant Bob Cory has opened a free health coaching service in Eureka for community residents in need of additional help understanding their medical situation.
Cory, who spent 35 years as a physician's assistant before retiring, will provide health coaching services including reviewing clients' health records, lab work and medications; recommending questions clients should ask their health providers; suggestions for healthy eating and exercise habits, and much more.
The health coaching services are free of charge to all clients; however, Cory will accept donations for St. Joseph Hospital's radiation oncology department for those who wish to contribute.
The idea to offer the community free health coaching services came to Cory earlier this year after he experienced the other side of health care – as a patient. Cory was diagnosed last spring with a tumor on his vocal cord and underwent radiation treatment at St. Joseph Hospital. Today he is healthy and happy, and back to running regularly.
"As a patient for the first time in my life, I saw the other side of health care," Cory said. "Too many patients don't understand the basics, like which medications to take when and what to ask their primary care provider."
"My goal is to bridge the gap between patient and provider," he added.
Cory has named his service "Never Holler Ho" health coaching, which is a personal motto meaning "never give up." Cory said the term has carried him through his personal and professional career caring for people on the North Coast, and he hopes his clients will be inspired by the positive message.
For more information or to schedule an appointment with Bob Cory for health coaching services, call the office at (707) 496-3732. His office is located at 2505 Lucas Street in Eureka.
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Sony Ericsson "Bao" leaked
All we have to go on with this latest Sony Ericsson leak are images, but here we bring you what's reported to be the forthcoming "Bao".
This leak follows the rumour we brought you earlier of Sony Ericsson's Xperia-based Android handset, code-named "Rachael".
The images of the Bao reveal an angular design, likened in looks to Nokia's "Prism" range of fashion phones.
We will keep you posted on Bao, and all other Sony Ericsson news, as we get it.


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Edward Poynings is appointed by Henry VII as deputy for Ireland, with instructions to take Carlow under control and to smother support for Perkin Warbeck.
Please log in to consult the article in its entirety. If you are not a subscriber, please click here to read about membership. All our articles have been written recently by experts in their field, more than 95% of them university professors.


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"Where Every Child is a Most Valuable Player"
We don't set up divisions with hard and strict parameters like other tackle programs. Our first and foremost concern is safety for all players and then placing the player where he/she is best suited. (yes, girls can hold their own with the guys in this program)
Our divisions are set with the following general guidelines and are dependent upon final registered numbers. These are guidelines however and you can expect variations to occur.
Ages 7-10 WITH LITTLE TO NO PREVIOUS TACKLE EXPERIENCE
No weight limits for ages 7-9. Age 10 and over 100lbs will be placed in Junior Varsity regardless of experience. This is primarily a developmental division. Football fun is in store but focus is on development of basic skills and confidence. It is low key and educational with light competitive level.
JUNIOR VARSITY - This is a traveling division (some games in San Ramon, some in Concord.
Ages 9-12
Age 9 - No weight limit and with tackle experience
Age 10 - Over 100lbs with or without tackle experience
Age 11 and 12 - Under 100 lbs and with or without previous tackle
VARSITY- This is a traveling division (some games in San Ramon, some in Concord.
Ages 11-14
Age 11 and 12 - over 100lbs
All players ages 13-14
Team mate requests in JV and Varsity are encouraged but groups of more than 5 players must have coaching staff provided.
Freshman are not grouped in official teams but in groups that learn together and play together as a growing developmental group.


text:
The following is an archive of a post made to our
'vox-outreach mailing list'
by one of its subscribers.
I for one think that the new scare of IE security would make people try new
browsers. Firefox is a very good alternative for the windoze user. Maybe
some plug ins available for the browser as well.
This might sound harsh but we can really sell this IE scare. It is slowly
trickling out to the masses...wish that I still had that sac bee article I
cut out of the paper.
Got milk?
----- Original Message -----
From: "Bill Kendrick" <firstname.lastname@example.com>
To: "LUGOD Outreach" <email@example.com>
Sent: Saturday, July 03, 2004 7:12 PM
Subject: [vox-outreach] Discs for STC
> We should put together some discs to give away at our booth at STC later
> this month.
> The software I've mentioned that seems STC-related includes:
> OpenOffice.org
> Mozilla
> LaTeX / LyX
> Inkscape
> Scribus
> Dia
> Should we put together a little ISO with the latest versions of these
> for Windows? (Rather than going with TheOpenCD or GNUWinII, which has a
> of non-writer-related stuff on them.)
> Does STC seem like an event where we should have Knoppix discs? Or should
> we just focus on 'Open Source in general', for now, rather than Linux
> specifically?
> Thanks!
> -bill!
> _______________________________________________
> vox-outreach mailing list
> firstname.lastname@example.com
> http://lists.lugod.org/mailman/listinfo/vox-outreach
vox-outreach mailing list
Hosting provided by:
Sunset Systems
Sunset Systems offers preconfigured Linux
systems, remote system administration and
custom software development.
LUGOD: Linux Users' Group of Davis
PO Box 2082, Davis, CA 95617
Contact Us
LUGOD is a 501(c)7 non-profit organization
based in Davis, California
and serving the Sacramento area.
"Linux" is a trademark of Linus Torvalds.


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text:
1- Take a piece of paper and draw a line down the middle
2- Write the GOOD things you have done on one side
3- Write the bad things on the other..
This is what God knows of you without Jesus in your Life :(
4- Now tear the paper down the middle
5- Confess the bad to Jesus.. be truly sorry & promise to do better
6- Then throw the bad side away.. (to the foot of His cross)
7- Now GO before Your father God with your Good things in hand
YES- NOW GOD ONLY SEES YOUR GOOD SIDE!! Feel better? ;)
Ask your father whatever is on your heart.. He loves & cares for You!!
Repeat this as needed.. Christ's sacrifice forgives it ALL.. and then-
PRAISE Jesus YOUR Savior! Read & Ponder on His Words Daily!
Last- DO ASK for His GIFT of the Holy Spirit that He Promised..
and then WATCH & LISTEN for the Spirit's Guidance for YOU!
Must We be "Born Again" to be Saved?
|Many Christians think "good" people may get to heaven.
Do you?
BUT Jesus said..
"Truly, truly I say to you, unless one is born again,
he cannot see the Kingdom of God" John 3:3
What does it mean to be "Born Again"?
It is a radical transformation that is brought about
through the supernatural work of the Holy Spirit!
Why must a person be "Born Again"?
1) We have a deceitful heart
"The heart is deceitful above all things, and it is
exceedingly weak--who can know it?" Jer 17:9
2) We have a dead spirit
"Once you were dead because of your
disobedience and your many sins" Eph 2:1
3) We have a deceived mind
"Satan, who is the god of this world, has blinded the minds of those
who don't believe. They are unable to see the glorious light of the
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Bouches-du-Rhône (Occitan: Bocas de Ròse, lit. "Mouths of the Rhône River") is a department in the south of France named after the mouth of the Rhône River.
Bouches-du-Rhône is one of the original 83 departments created during the French Revolution on March 4, 1790. It was created from part of the former province of Provence and the principalities of Orange, Martigues, and Lambesc. It lost part of its territory in 1793, including Orange and Apt, when the Vaucluse department was created.
The history of the area is closely linked to that of Provence. Marseille has been an important harbor since before Julius Caesar's conquest of Gaul. The Roman presence has left numerous monuments across the department.
Marseille contains an important harbor.
Other cities include:
Rivers include:
Lakes include:
Mountains include:


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When it was decided to adopt English as the medium of instruction in Rwandan schools, the authorities knew it would not be a walk in the park.
Teething problems were expected and most have been surmounted. The most pressing problem was the availability of English teachers and mentors, therefore the country decided to recruit in neighbouring countries.
The teachers have been working, they have honoured their end of the bargain, it is now time for Rwanda Education Board (REB) to do the same.
If the 1000 teachers recruited for the exercise complain that the government owes them arrears in salaries and other benefits, how would REB have coped with 6,000, the original figure it had sought?
The best incentive for a worker is a conducive working environment and the right tools. If mentors can only receive their transport allowances after working for 12 months and their salaries are two months behind schedule, how does REB expect them to perform well?
These financial woes blot our government's image as an efficient well oiled machine that always has its house in order. It is a very pertinent issue that should be worked out urgently because our children's future cannot be entrusted in the hands of hungry and unmotivated teachers.


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Hiker Ken Farley went up the Sam Merrill trail at the top of Lake Avenue — way up — last weekend and took a bunch of photos that depict both the devastation of the Station Fire and the remarkable landscapes that were saved.
The above shot is from Upper Millard Canyon looking to the east toward Mt. Disappointment and Mt. Wilson. You can see the burned out areas down below, and the beautiful greenery that remains.
Ken has more insight than your average bear into our mountains. He's a geophysicist and chair of the division of geological and planetary sciences at Caltech. I believe he was accompanied on the hike by his wife, fellow geologist Kristen Farley, a former academic herself who is the big boss of Pasadena Up & Moving, the exercise advocates who plan the monthly walks with the mayor around the Rose Bowl.
Both hikers are ultra-marathoners who know the mountains as well as anyone. Today and for the next coupla, no one is supposed to know the mountains as we stay out of them because of the intense danger of debris flows in this rain.


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On the next 'Arrested Development': Mitch Hurwitz on what's after Season 4Add to Favorites | Game of Thrones
"Arrested Development" Season 4 premiered on May 26, which means more than enough time has passed to ask what's coming next for the Bluth family.
Series creator Mitch Hurwitz previously said he wants new "Arrested Development" every two to three years, while Netflix CEO Reed Hastings said the company is open to making more seasons. Then there's the long talked about "Arrested Development" movie, which according to all reports is still in the works. Even though it's not clear what will come next, Hurwitz promised during a recent conference call that fans will know about it when the next installment of the Bluth family saga is decided on.
"I don't have a timeline yet. I don't have a time table on that. I do want to work on it," he says. "If there's more, I promise you, we'll put a date on it. The last time, it got out of hand."
That means that there won't be another situation where a Bluth reunion is promised for seven years. Hurwitz says he has a story planned for what comes next, even if he did finish Season 4 with what he thought was a satisfying ending.
"I really hope that if we were never to come back again and look back at the last episode and say, 'Wow, look at that, [George Michael] broke out of the Bluth circle.' The whole show is a circle and everybody is arrested, everybody keeps falling back in the same patterns," Hurwitz says. "George Michael broke the circle. It's loaded, and really what is the next step if you were to have that type of situation with your father, the closest person to you."
Fortunately Hurwitz promises, "I do have answers for that," but he says someone just needs to let him make it. That is easier said than done, as there a complicated cast schedules and rights issues to work out. Still, he seems to want a film to be the next installment of the Bluths' saga.
"My hope was and is that we would do a theatrical movie. This is all complicated by the fact that there are existing rights. It's not the kind of thing where we can go out and say Warner Bros. wants it and New Line wants it, et cetera, et cetera," Hurwitz says. As for whether the movie could go straight to Netflix, he admits, "I'm sure there is a scenario where this is a made-for-Netflix movie," though it hasn't been explored yet.
Just like he played with the show's format in Season 4, Hurwitz promises that he's going to mess with the traditional model for either television or film with what he makes next. That, to him, is what keeps things interesting, and is why he saw eye-to-eye with Netflix to begin with. At least the cast still wants to work together, so there is a good chance of more "Arrested Development" in the future.
"I think if I'd done the exact same show I did last time, there would be blowback for that," he says. "My interest is in telling the story of this family. I guess it's kind of like give us the canvas and let's see what we come up with."
Hurwitz adds, "I hope that no matter what we do there will always be the suggestion of another step."
There will be at least some new "Arrested Development" content fairly soon, though. Hurwitz says that there are scenes that weren't included Season 4 that Netflix is going to roll out in the future in order to provide something new for fans to see. He also reveals one joke about "Mexican Romneys" that didn't make the final cut of Season 4.
"George Sr. has this land in Mexico, and they were going to -- I shouldn't give this stuff away, oh my god -- they were going to be constantly sort of spooked and chased off the by these really handsome men. I was going to try to get George Clooney and people like that," he says. "It's like, 'Who are these guys? Who are these Mexicans that keep trying to get us off their property?' At one point they were going to say, 'We are the Mexican Romneys!' Because there's a whole sort of strain of Mexican Romneys down there from the period in which they were expatriates and intermarrying and whatever -- I should say, polygamous marrying down there -- his grandparents started a little camp down there."
As for people reediting Season 4 into a new order, Hurwitz says he couldn't be more pleased.
"I love it. It's like sampling, you know? It's really interesting," Hurwitz says, admitting that he at one point talked to Netflix's tech team to see if there was a way to allow viewers to press a button and jump to different characters' perspectives within one scene. "Flattered is kind of an obnoxious word, but I'm very gratified that people are kind of taking this material and ingesting it. What could be a better thing? ... I would say more than anything, I love the fact that it inspires creativity."


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When I first mentioned the title of this post to my girlfriend, she misheard and thought there was an extra "t" at the end.
One hasty explanation later I have avoided banishment to the shed. All of which is mildly ironic as the tar command comes with a whole alphabet of options, many of which are about to get used here.
As it's name suggests, the venerable tar command ( Tape ARchive) has it's roots back in the time when computers were the size of a small semi in Dagenham and punch cards and tapes were the acme of the Programmer's art.
Now I'm going to use it for backing up data on my assorted Ubuntu machines.
What I want to do here is :
- work out how much data I need to backup
- create a full backup of all of my data
- make sure I know what files have been backed up
- test the restore of a file from the backup
- make subsequent incremental backups
In the course of this odyssey, we will discover that du has a human face and that tar has a bit of a yellow streak.
There are several things that can go horribly wrong when playing around with tar, so I'm going to test everything on a small subset of files…that I have safely stored elsewhere.
Speaking of which… Continue reading


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Sniper Kill medal
Redirected from Sniper Kill Medal
8,846pages on
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this wiki
|Sniper Rifle Kill
|Points worth
The Sniper Kill medal is a multiplayer medal awarded in Halo 2, Halo 3, Halo: Reach and Halo 4. It is obtained by killing an opponent with a headshot using the Sniper rifle (Halo 2, 3, Reach and 4) or Beam Rifle (Halo 2,3 and 4 only) in Halo 3 Matchmaking or Multiplayer, while a plain kill with either weapon will get you the medal in Halo 2 and the Halo 3 Beta.
- After you kill an opponent with a sniper weapon, a message appears on your screen that says: "You sniped (player)". This does not happen in Halo 4.
- It is available in all Multiplayer gametypes where a sniper weapon is available and it is also possible to get this medal in the Halo 3 campaign, with either of the sniper weapons, Battle Rifle or Carbine and the M6G Pistol. Bungie difficulty rating of 1 out of 10. It is represented by a six-pointed star with crosshairs.
See alsoEdit
|Halo 2 medals
|Consecutive Kills
|Double Kill • Triple Kill • Killtacular • Kill Frenzy • Killtrocity • Killimanjaro
|Killing Spree • Running Riot • Rampage • Berserker • Overkill
|Special Kills
|Sniper Kill • Stick It • Splatter • Carjacking • Assassin • Bone Cracker
|Bomb Carrier Kill • Bomb Planted • Flag Carrier Kill • Flag Captured • Flag Taken • Flag Returned


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Emmanuelle Alt in Topshop Baxter Skinny Jeans in Black
Fsahion month may be over, but who doesn't love a shot of Emmanuelle Alt. The EIC of Vogue Paris was spotted strolling through Paris with Caroline de Maigret in between attending the shows.
She wore her very worn in pair of Topshop Baxter jeans with a leather jacket and Marant heels. Then there is the surprise no show of one of her signatures, a belt. I highly doubt this will mean the end of belts, but it is a bit of a shock not to see a staple on her. You can click here to purchase Topshop jeans from their website.
Emmanuelle Alt in Topshop Baxter Skinny Jeans in Black
Emmanuelle Alt made a rare appearance at Barneys for Inez and Vinoodh fragrance launch in New York. The Vogue Paris editor wore her favorite Topshop Baxter Skinny Jeans in Black with a Balmain jacket and some black suede pumps.
This is definitely Emmanuelle's signature look that she has worn. I love that she sticks to it and changes it up with an insane jacket to freshen up her look. I cannot wait to see what she will be wearing during Paris Fashion Week. I am hoping we will see her pull out some flares again and/or her white skinny jeans. You can click here to purchase these jeans from Topshop.
Amanda Seyfried in AG Adriano Goldschmied Denim Shorts
Amanda Seyfried was pictured out and about in Los Anegles, California over the weekend while wearing a pair of AG Adriano Goldschmied, Bonnie in Fade, denim shorts with a burgundy plaid sleeveless shirt from Topshop.
I'm a huge fan of Amanda's, both style wise and acting. I think she's such a natural beauty and so down to earth, she never really pays any attention to the Hollywood life. I love this combination of the shirt and denim shorts on her though, she looks good! Buy AG Jeans online at Shopbop.com.
Images courtesy of INFdaily.com.
Beyonce in Topshop Paisley Print Leigh Jeans
Beyonce once again wore some cool denim for some photos on her Tumblr. For her trip in Berlin, the superstar wore a pair of Topshop Paisley Print Leigh jeans with an anorak and her staple Marant sneakers.
This is the first time we have seen Beyonce wear a pair of jeans that are relatively affordable by Topshop. I do think the detail on these are really cool and look perfect the way she styled them. I'm so envious of her anorak collection. You can click here to purchase these jeans from Topshop for $96.


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Full-Time Program
Full-time students devote a substantial amount of their time during the academic year to the study of law. The full-time program is six semesters long (three academic years) with most classes held between the hours of 9:00 a.m. and 5:30 p.m. However, during their upperclass years, full-time students may take courses in the part-time program, which are typically held in the evenings.
During their first year, full-time students take 31 semester hours of required course work. After the first year, students are required to take a course in Professional Responsibility and fulfill the Upperclass Legal Writing Requirement in addition to their elective course of study. In the upperclass years, full-time students are expected to enroll in 12-16 credit hours each semester.
The essays in the Curriculum Guide suggest how upperclass students might design their upperclass curriculum.


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My Account
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Ronix Parks Wakeboard Bindings
Key Features
Lightest heat formed custom fit boot
Lower cut boot with Intuition + liners
Double Last/Soft density perforated liner
Tool-less mounting hardware
Low friction eyelets
Our Price $439.99
Sale Price $349.99
Availability: Sold Out
- Please note: This item can only be shipped to U.S. addresses.
detailsback to top
Product DescriptionParks Bonifay and the Ronix designers crafted their lightest heat formed custom fit boot with plasmatic portions of a synthetic film coating, tipping the scale under 1.6 lbs. This new Parks boot is built for riders that want the most mobility out of a closed toe boot, without sacrificing heel hold down. This lower cut boot with the Intuition + liners are made with a lightweight breathable shell material for the most in side to side latitude. Parks Bonifay's custom orthotic freestyle inspired signature footwear has more lateral freedom than the One or Cell boot. The Double Last creates an exact fit from your foot to the shell of the boot for the best in comfort and response. The softest density liner is also perforated for amazing mobility. Removable J-bars customize your heel pocket while Feetbelts and Silicon ink in the heel area offer the ultimate heel hold. Tool-less mounting hardware. Low friction eyelets.


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The Valley City Area Chamber of Commerce's annual chili cook-off and community olympics are scheduled Monday evening to kick off the North Dakota Winter Show.
The annual events, which are known as friendly and fun competition among community members, groups, businesses and organizations, will take place at the Winter Show's main arena. Sign-up forms are on the Chamber's website, www.valleycitychamber.com, and must be sent by Saturday. The chili cook-off begins at 5:30 p.m., and the community olympics begin at 7 p.m.
More in Friday's Times-Record.
A Valley City bar has a new name and new owners. Scott Sandvik, Valley City, and Jerry Jarvis, of Arizona, are the new owners of My Bar, formerly called The Ram, which was owned by Michelle Brendmoen. Sandvik and Jarvis became the owners of the bar, located at 240 East Main Street in Valley City, Feb. 19.
My Bar plans to have entertainment regularly, starting with Big Hammer Karaoke on Friday, March 7 from 9 p.m. to close. Sandvik said, "Come on down for entertainment after the Winter Show concert."
More in Friday's Times-Record.
The State Board of Higher Education Thursday named Valley City State University President Dr. Steven Shirley as the next president of Minot State University, Minot, N.D., said MSU spokeswoman Linda Benson. More in Friday's issue of the Times-Record.
Several members of a Barnes County family were arrested Tuesday on a variety of charges including possession of methamphetamine, possession of stolen property, and assault.
Barbara Case, 45, of Wimbledon, was charged in Barnes County District Court for possession of a controlled substance – methamphetamine, a class C felony: and possession of stolen property, a class A misdemeanor.
Two new dentists have joined Dr. Ted Hagen at Concept Dentistry in Valley City. Dr. Brian Bulik and Dr. Ann Slama each have skills that allow the practice to offer a variety of modern services.
Read more in Thursday's Times-Record.
The Barnes County Senior Center will be home to an American Association of Retired Persons Smart Driver Course 1 p.m. May 8, said Peter Farrelly, an AARP-certified instructor who lives in Valley City. More in Thursday's issue of the Times-Record.


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A brief interview with Rob Worthing
Tenkara needed someone to play the handsome doctor role, so Rob Worthing stepped in. One third of the Utah-based Tenkara Guides, he's an emergency-room physician, wilderness-medicine expert and passionate tenkara angler.
Not to mention a tireless investigator of yarn translucence. While searching for the most killer of Killer Bug yarns, Rob famously spent two days at the Blazing Needles knitting shop in Salt Lake City, asking the nice ladies there to show him yarn after yarn after yarn, which he would tie into a fly on the spot (yes, he brought his vise with him) and drop into a glass of water to judge its killerness. Forty soaked flies later he had the wool yarn he was after: Jamieson's Shetland Spindrift "Oyster," the essential ingredient of the Utah Killer Bug, the signature fly of the Tenkara Guides.
Rob recently took some time out from saving lives and confusing knitting-shop employees to talk tenkara with me.
ASHLEY: How did you discover tenkara?
ROB: Through backpacking. I'm a Fellow of the Academy of Wilderness Medicine, and teach med students and physicians how to apply medicine to the backcountry. Two of my prior students wanted to do a pack trip in Utah. One was a native Alaskan fly fisherman. Big flanneled dude nicknamed Moose. Looked like the Brawny paper towel guy. I went in to a local Western fly-fishing shop to look into a new rod for backpacking. Didn't really feel like spending $1000 for a decent 5-piece setup. So I went on BackpackingLight.com, heard about Tenkara, and the rest is history.
ASHLEY: What do you like about tenkara versus other styles of fishing?
ROB: For me, it really is about the simplicity. Dissect a process until you're left with only the most basic functional elements, the elements that really matter when it comes to success. Then concentrate on perfecting those elements. That's something I was already doing in other aspects of my life. If I don't absolutely need it to get a job done, then it goes away. When Tenkara came along, it just made sense to do the same thing with fly fishing.
ASHLEY: What is your style of tenkara? "One fly" purity? Hybrid?
ROB: I have fun fishing both traditional tenkara and hybrid styles. Either way, I try to keep the emphasis on the fish. A study of entomology can be very useful. But the best anglers begin and end with the study of fish. I try hard to concentrate on trout biology - making notes on the water, reviewing scientific literature on trout behavior, diet, migratory patterns, etc. I'm pretty intrigued to see how far pure presentation can take you. If a guy or girl fishes with one generic pattern for 20 years, on a diverse collection of waters, and placing all the emphasis on presentation, what kind of angler will you get? I dunno, but it'd be fun to find out.
ASHLEY: What are your favorite rods, flies, or other gear?
ROB: My favorite piece of gear is my fishing partner. The right partner doubles my vision, doubles my casts, doubles the amount of water I can cover, doubles the number of times I place a fly in front of a fish, doubles the amount I learn, and doubles the rate at which I improve. Fish with each other, not just near each other.
ASHLEY: Where do you like to fish?
ROB: In as many different places as possible.


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You can plant seeds of generosity through your gifts that will grow and positively impact the programs, parishes, schools and Catholic organizations throughout the Diocese of Lubbock. You can accomplish more than you ever thought possible with the wise and thoughtful sharing of the blessings God has entrusted to you.
Please contact Renée Underwood, Managing Director, by email or call 806-792-3943, ext. 206. We are here to help you plant seeds of generosity to grow the Catholic Church in West Texas.
P O Box 98700 Lubbock TX 79499-8700 • (806) 792-3943, xt. 206 • Click here to email us.


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Stores »
so simple and unique - these make me think of cherries!
We are a community of shoppers sharing our best finds from across the web.
© 2015 ThisNext, Inc. ThisNext is a member of BUZZMEDIA Entertainment, a division of BUZZMEDIA.
Create your own free digital magazine at our new site Glossi.com


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The shirt in the post below (last picture) is from Forever21. I got it when I was probably a sophomore in college. (see, I can make their clothes last ;)
Question for you all....if you ask me the brand or where something is from...should I add it in to the post you've seen the item in, or should I put it at the top of another post like I did above?
Since this post was sparked my the oven mitt, I am going to include some fun pics from a cooking class I went to last Thursday afternoon :) My friend Tallee nannies for a sweet family and the daughter, Vivian, hosted a cooking class. She is going to NYC in a few weeks and Tallee thought it would be a good way to raise some money for her trip! Plus, she is a WONDERFUL cook! She has made some of the most fabulous cakes I've ever seen. We had a lot of fun :)
The hosts made cupcakes with the initials of those who were planning to attend..cute idea!
The printed up the recipes for us!
Sweet Vivian
Cameron juicing limes
Tallee, Kristen & Jen working on the Key Lime Pie
Jen & Cameron working on the peanut butter balls. You guys they are SO DELICIOUS! I'll post the recipe!
Jen snacking :)
I am putting the filling in the pie
Tallee, Vivian & Cameron
Jen dipping the peanut butter balls in chocolate
Our cooking class :)
Vivy sent us home with treat bags (peanut butter balls inside!!)
Here is the recipe the hosts gave us for the DELISH Chocolate Dipped Peanut Butter Balls
1 1/2 sticks butter, melted
1 cup peanut butter
1 lb. box of powdered sugar
4 cups of Rice Krispies
2 bags of chocolate chips (we used Ghirardelli)
-Put Rice Krispies in a gallon bag and whack until slightly crushed.
-In a mixer bowl, combine butter and peanut butter while gradually adding sugar and cereal. Mix everything together and the mixture will be very dry.
-Roll peanut butter mixture into small balls and place on a cookie sheet covered with wax paper.
-In a double boiler, melt all chocolate over medium heat then reduce heat to low. Dip the peanut butter balls in the chocolate. Refrigerate then serve when chocolate is hard.
I am so happy it is Friday. This week hasn't been the greatest but ended up much better than it started :) I plan to relax tonight (all weekend really)..I wish it would include a glass of wine but I don't think my prednisone would like that ..or work as well as it should. With my goal being stated to relax and rest, our sweet friends Jessica & Kyle offered to bring us dinner tonight. They are so sweet and we love hanging out with them.
I am liking having my new blog domain :) I've had a few people ask about the blogs I had listed on my page. Well, I don't know WHERE they are :( When I go to layout, it says I've never entered any in...but I have. I'm hoping they are lost in transition...but if they don't appear back in a few days, I'll be adding them back :)
Hope you all have a wonderful weekend & thanks for being such sweet bloggy friends!
xoxo ~ Megan


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The following is an archive of a post made to our
'vox mailing list'
by one of its subscribers.
On Wed, 2002-11-27 at 15:58, Joel Baumert wrote:
> The version of squirrelmail that you are using is the same
> one that I think was used to attack my system. You might
> want to either update or otherwise make sure you are not
> vuneralble...
> Joel
Gonna check with SuSE as they tend to fix things in source rather than
issue new upgrades.
Matthew Johnson <email@example.com>
vox mailing list
Hosting provided by:
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Sunset Systems offers preconfigured Linux
systems, remote system administration and
custom software development.
LUGOD: Linux Users' Group of Davis
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and serving the Sacramento area.
"Linux" is a trademark of Linus Torvalds.


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No bolt to L.A. for Chargers?
Funding remains the elephant in the East Village, the Chargers' location to built their version of the Dean Dome.
That quest took a hit recently when it was ruled hotels could be taxed to fund the Convention Center expansion at its current location, which derails the Chargers' idea.
"The project still has a long way to go including potentially several years of legal appeals all the way to the California Supreme Court and the entire Coastal Commission process, which hasn't even begun,'' said Mark Fabiani, the Chargers' lead man in the stadium search.
The Chargers hope that taxing mechanism is eventually squashed, so they can construct a stadium with a soft, retractable roof and convention space.
"Securing voter approval for a multi-use facility outside of the coastal zone but next to Petco Park and the Convention Center remains a much better solution,'' Fabiani said.
Maybe, maybe not.
What's obvious is Los Angeles produced more than its legendary smog on Friday. It became clear the scenario of the NFL's return there remains clouded in a haze of broken promises.


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A new fence line for the next phase of work on the Physical Sciences Building Project will be established on Monday, July 6. he new construction area will extend south of the West Experiment Station, west to Goessmann and north to the Lederle Graduate Research Center lowrise. Vehicle access to the Goessmann loading dock will be maintained.
Starting Monday, July 6 and running approximately five weeks, or until completion, fire hydrants on campus will undergo an annual flushing process. Flushing will begin at 3 p.m. and run until 9 p.m. every weekday. The perimeter of the campus will be done early in the shift and the core later in the shift. Residential areas, including North Village and Lincoln Apartments, will be notified two days prior to flushing.


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Norfolk State University BEHOLD Magazine
The word "BEHOLD" is often used by those who love Norfolk State. It sums up the excellence of the University and pride felt for it. That is why when it came to naming your magazine–featuring alumni and their achievements as well as the accomplishments and progress taking place at norfolk State—"BEHOLD," easily came to mind.


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Photo by Andrea Chu
YIELD: Makes 6 servings
Mix garlic, pepper, and 1 1/4 teaspoons coarse salt in small bowl; rub all over steak. Let stand at room temperature 1 hour.
Spray barbecue grill with nonstick spray. Prepare barbecue (medium-high heat). Grill steak until charred and cooked to desired doneness, about 7 minutes per side for medium-rare. Let rest 10 minutes.
Mix tomatoes and all remaining ingredients in medium bowl. Season to taste with salt and pepper. Thinly slice steak; arrange on plate. Spoon salad over steak and serve.


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I THINK TRINIDAD HAS REACH THE BOTTOM.KIDS KILLING KIDS COME ON THATS SAD AND SCARY [/img][/email]
he truely is the sweetest kid and the boys that did this to him really are monsters who have hearts made of stone assuming they have hearts
..:: alwayz in our heartz ::....:: foreva in our memoriez ::..<3 R. ii. P. SeaN LuKe <3
If i was d boy's mom i wud have been hanged long time for killin dem two bullerman


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Saturday, January 17, 2009
About Me
- Name: Greg Mankiw
- Location: United States
I am a professor and chairman of the economics department at Harvard University, where I teach introductory economics (ec 10). I use this blog to keep in touch with my current and former students. Teachers and students at other schools, as well as others interested in economic issues, are welcome to use this resource.
Naked Self Promotion
Previous Posts
- Obama rejects the Pigou Club
- The Brain Science of Irrational Exuberance
- How to Become a Trillionaire
- More Spending Stimulus Skeptics
- In Praise of Sweatshops
- A Defense of TARP
- Fama on Fiscal Stimulus
- Ted is more relaxed
- Triangles vs Gaps
Advice for Students
- Advice for Aspiring Economists
- Where do economists come from?
- Choosing a Graduate Program
- Working Before Grad School
- Advice for Grad Students
- Advice for New Junior Faculty
- Which math courses?
- Why Aspiring Economists Need Math
- Love Econ, Bad at Math
- Summer Reading List
- JD vs PhD: My Story
- My Life as a Student
- PhD or not?
- Education Beyond the Classroom
- An engineer seeks career advice
- A Question about Learning Economics
- Good Academic, Bad Human Being
- Are B-school economists different?
- How to Write Well


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Samsung has improved on the already impressive Series 5 and Series 9 Notebook ranges and just unveiled them at CES.
The new Series 9 Notebook is 21 percent thinner than its predecessor and despite also being 28 percent smaller overall, it still has a stunning aluminum unibody. The Series 9 manages a sturdy 10 hours battery life even with the 13.3 or 15in SuperBright Plus screens and second generation Intel Core Procesors. Oh and it boots it around only 9 seconds.
The Samsung Series 5 Ultrabook is pretty, sure. And yeah it has the power of Intel i5 in both 13.3 and 14in models. But somehow Samsung has also managed to cram in a DVD drive. Take that MacBook Air.
The Series 9 will be out in February at $US1,400 and $1,500 for the 13.3in and 15in models respectively. The 13in Series 5 with a 500GB hard drive will be US$900, or with 128GB SSD, $1,100 – both are due out at the end of January. The 14in, due out around March, should start at $950.
This article originally appeared at Stuff.tv
Copyright © Stuff.tv
Issue: 339 | June 2015
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Just a bunch of nonsnsical pics http://marinaibiza.deviantart.com/
"Boobies and Such". That folder name just made me chuckle. Seriously, though. I really liked your Candlelight picture. I left a couple of feedback tips as requested, but I think it looks really good overall.
*Goes to create a "Buttocks and Whatnot" folder*
Seriously, though. I endorse this profile with its equal-opportunity nudity. :D


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Polycystic Ovarian Disease: Treatment Protocols
Polycystic Ovarian Disease: Treatment Protocols
Abstract: We should stress that that before addressing failure for any treatment protocol, the treatment cycle should be properly evaluated and monitored. For failed treatment with Gonadotropin, there is a question to be addressed, do we embark on ovarian drilling (the replacement of the obsolete wedge resection) or do we start In vitro fertilization? Introduction: Pathophysiology: The diagnosis of PCOD does not require the presence of polycystic ovaries. However, it is believed that 80-100% of women with PCOD have polycystic ovaries, which are defined as the presence of 8 or more small (2-8 mm) follicles in each ovary. Polycystic ovaries also can be present in other causes of androgen excess and in approximately 20% of normal women. Conclusions
Stein and Leventhal were the first to recognize an association between the presence of polycystic ovaries and signs of hirsutism, amenorrhea, oligomenorrhea and obesity. Subsequently, it was reported that after successful wedge resection of the ovaries in women diagnosed with Stein-Leventhal syndrome, menstrual cycles became regular and these patients were able to conceive. Consequently, it was thought that a primary ovarian defect was the main culprit, and the disorder came to be known as polycystic ovarian disease (PCOD). Further biochemical, clinical, and endocrinological studies have shown an array of underlying abnormalities, though it may occur in women without ovarian cysts. Since the era of Stein and Leventhal, many treatment protocols have been implemented for the treatment of PCOD. The aim of any treatment is to get a live birth of a singleton from a healthy mother. To achieve such result, treatment by Clomiphene Citrate, Gonadotropin and Gonadotropin analogs (GnRh-a) have been reviewed. Most of the work done are on the favor of Rec-FSH as a treatment without the addition of GnRh-a. It should be stressed on the importance of adding Metphormin for Hyperinsulinemic patients as it improves the treatment results as far as ovulation rate, pregnancy rate, abortion rate and ovarian hyperstimulation are concerned.
In 1935 the pathology of polycystic ovarian disease (PCOD) was described by Stein and Leventhal. It is a clinical syndrome consisting of menstrual irregularities featuring amenorrhea, oligomenorrhea, infertility, masculine type hirsutism and obesity. Since that time many theories have been postulated for the pathology causing the disorder. In the meanwhile and because of the uncertainty of the underlying etiology, many treatment protocols, surgical and medical have been recommended to control that disorder.
Treatment Protocols:
It is given 50mg twice daily starting on the second day of the menstrual cycle and given for 5 days. The treatment cycle should be monitored by ultrasonic folliculometry and hormonal assays, so as to know whether ovulation is induced or not. 50-80% of cases will ovulate by CC however pregnancy rate is only 40-50% (Cudmore and Tupper, 1966 ; Johnson et al, 1966). Before addressing failure of treatment, we should know is it failure to get ovulation or failure to get pregnancy. If it is failure to get ovulation we shift to Gonadotropin treatment. If it is failure to get pregnancy (and we did had good ovulation, we address the case as unexplained infertility for which we either do Controlled Ovarian Hyperstimulation (COH) with or without Intrauterine insemination (IUI) and if failed we shift to In Vitro Fertilization (IVF).
The Gonadotropin used is either Human menopausal Gonadotropin (HMG), Urinary Gonadotropin (uFSH), Purified Gonadotropin (p FSH) or recombinant FSH (Rec-FSH). The Rec-FSH is produced by genetic engineering from Chinese Hamster Ova (CHO) and it is pure FSH. The idea of using FSH alone without LH in these patients is that the high levels of LH lead to poor oocyte quality, reduced rate of fertilization and pregnancy and increased rate of early abortion. The use of Rec-FSH will guarantee purity of FSH, lower dosage needed to induce ovulation and shortage of stimulation period required for sound ovulation.
The gonadotropin is used by either step up or step down method. By step up we start with small dosage of 75U and increase it up to 150U. In step down method, we start by high dosage of 150U and gradually decrease the dosage. Both methods have comparable results. Rec-FSH is more superior to uFSH (Coelingh Bennink et al. 1998, Daya and Gunby, 2000), Rec-FSH is the Gonadotropin of choice.
The addition of GnRh analog: In the past many voices said that the addition of GnRh-a to gonadotropin treatment will improve the treatment results. However Fleming (1988), Hamburg (1990) and Hompes (1986), did not find any significant difference as far as pregnancy rate is concerned. Regarding Ovarian hyperstimulation and abortion rate, there was no significant difference. So, At the moment, the addition of GnRh-a is not recommended.
As long as hyperinsulinemia is associated with higher levels of androgen and lower diameters of follicles, the addition of insulin sensitizers is highly recommended.
The hyperimsulinemic women (45%of PCOD) are associated with higher levels of Estrogen, higher number of immature small follicles (nuisance follicles), higher incidence of ovarian hyperstimulation and higher incidence of abortion. From here we got the idea of adding Metformin to the treatment protocol, either in addition to CC or FSH.
Metformin (Glucophage) reduces hepatic glucose output, decreases intestinal absorption of glucose, and increases glucose uptake in the peripheral tissues (muscle and adipocytes). It is a major drug used in obese patients with type 2 diabetes. It is given by mouth 500 mg three times daily after meals.
Documented hypersensitivity; renal impairment (serum creatinine greater than or equal to 1.5 mg/dL in males and 1.4 mg/dL in females or a CrCl of less than 60 mL/min); any condition resulting in low CrCl, such as cardiovascular collapse from acute myocardial infarction, septicemia, and metabolic acidosis with or without coma; including diabetic ketoacidosis; metformin should be temporarily withheld at the time of or prior to a radiologic procedure involving intravenous administration of iodinated contrast material and restarted 48 hours subsequent to the procedure after renal function has been reevaluated and found to be normal.
It was found that in a study done by (Nestler et al., 1998) when Metformin was given to obese anovulatory women, high rate of ovulation occurred compared to placebo. The same happened if the metformin was added to CC, leading to reduction of nuisance follicles, reduced estradiol on day of Human chorionic gonadotropin injection , reduced rate of ovarian hyperstimulation and reduced rate of abortion.
So far, most of work done on that area did not find significant increase of fetal abnormalities, on the contrary the abortion rate was decreased.
Wedge resection of the ovaries is mentioned to be condemned; it is the operation that is associated with destruction of already diseased ovaries, and might transfer the patient from ovulatory problem to ovulatory and tubal problem, that is because of the postoperative adhesions.
Laparoscopic ovarian drill is the substitute for wedge resection. The postoperative adhesion is lower that in wedge resection.
The question is, If there is good ovulation but no pregnancy, will the patient benefit from Ovarian drill or shall we consider it as unexplained infertility and move to COH with or without IUI or IVF.
If there was resistance to get ovulation by either CC or FSH, A trial of drill would not do any harm. The drill should be followed by Ovarian stimulation, because the effect of the drill would not last long.
We should stress that that before addressing failure for any treatment protocol, the treatment cycle should be properly evaluated and monitored. For failed treatment with Gonadotropin, there is a question to be addressed, do we embark on ovarian drilling (the replacement of the obsolete wedge resection) or do we start In vitro fertilization?
The diagnosis of PCOD does not require the presence of polycystic ovaries. However, it is believed that 80-100% of women with PCOD have polycystic ovaries, which are defined as the presence of 8 or more small (2-8 mm) follicles in each ovary. Polycystic ovaries also can be present in other causes of androgen excess and in approximately 20% of normal women.
Click here to find a doctor or for more symptoms and treatment options for endometriosis.
Originally presented: Lotfi, G (2002): Polycystic ovary syndrome: Treatment protocol. Obstetrics and gynecology annual meeting, Suez Canal university, Ismaila. Egypt. April 25-26, 2002
Adams J, Polson DW, Franks S: Prevalence of polycystic ovaries in women with anovulation and idiopathic hirsutism. Br Med J (Clin Res Ed) 1986 Aug 9; 293(6543): 355-9.
Conway GS, Agrawal R, Betteridge DJ: Risk factors for coronary artery disease in lean and obese women with the polycystic ovary syndrome. Clin Endocrinol (Oxf) 1992 Aug; 37(2): 119-25.
Coulam CB, Annegers JF, Kranz JS: Chronic anovulation syndrome and associated neoplasia. Obstet Gynecol 1983 Apr; 61(4): 403-7.
Cumming DC, Yang JC, Rebar RW: Treatment of hirsutism with spironolactone. JAMA 1982 Mar 5; 247(9): 1295-8.
Donesky BW, Adashi EY: Surgically induced ovulation in the polycystic ovary syndrome: wedge resection revisited in the age of laparoscopy. Fertil Steril 1995 Mar; 63(3): 439-63.
Ehrmann DA, Barnes RB, Rosenfield RL: Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 1999 Jan; 22(1): 141-6.
Johnson JE Jr, Cohen MR, Goldfarb AF et al, The efficacy of clomiphene citrare for induction of ovulation. A controlled study. Int J Fertil 1966. 11, 265-270
Kiddy DS, Hamilton-Fairley D, Bush A: Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome. Clin Endocrinol (Oxf) 1992 Jan; 36(1): 105-11.
Lotfi,G: Polycystic ovary: Normal variation. Post Graduate Doctor. 1991. 16.
Nestler JE, Jakubowicz DJ, Evans WS: Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome. N Engl J Med 1998 Jun 25; 338(26): 1876-80.
Polson DW, Adams J, Wadsworth J: Polycystic ovaries--a common finding in normal women. Lancet 1988 Apr 16; 1(8590): 870-2.
Rittmaster RS: Hirsutism. Lancet 1997 Jan 18; 349(9046): 191-5.
Stein I, Leventhal M.: Amenorrhea associated with bilateral polycystic ovaries. Am J Obstet Gynecol. 1935; 29: 181.
Stein IF: Duration of infertility following ovarian wedge resection. West J Surg 1964; 72: 237.
Stumvoll M, Nurjhan N, Perriello G: Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med 1995 Aug 31; 333(9): 550-4.
Velazquez EM, Mendoza S, Hamer T: Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy. Metabolism 1994 May; 43(5): 647-54.
Zawadzki JK,, Dunaif A: Diagnostic criteria for polycystic ovary syndrome: Towards a rational approach. In Dunaif A, Givens JR, Haseltine FP, et al, ed. Current issues in Endocrinolgy and Metabolism. Oxford: Blackwell Scientific Publications; 1992: 377.


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Cirque Du Soleil Videos
NeNe Leakes Takes on Broadway
The star of "The Real Housewives of Atlanta" is about to make her Broadway debut in "Cinderella."
Kathleen Sebelius Resigns, Obama to Announce Replacement
about two -- what was that? A bat? Was that a bat? That's somebody throwing something at me? Is that part of cirque du soleil ? My goodness. I didn't know solid waste management was so controversial. Good she didn't play softball like
Cirque Du Soleil Performs Live in Times Square
Performers celebrate the 15-year anniversary of the first performance of "La Nouba."
Magic Money: It's Edgy, It's Dangerous, It's Las Vegas
Reporter: The mgm grand president, scott cebelo was talking about copperfield's success but reluctant to talk about a cirque du soleil performer, a publicist cutting our interview short. Is it safe? It is very safe. Not about david copperfield
Cirque Du Soleil Acrobat Falls from 'Wheel of Death'
THIS ONE AT CIRQUE du SOLEIL . A cast member slipped and fell ..... of death. THIS MORNING, ONE CIRQUE du Soleil performer is lucky to be alive ..... off the wheel on friday night. CIRQUE du SOLEIL WOULD NOT Confirm his identity
Cirque Du Soleil Performer Survives Fall from 'Wheel of Death'
On the Las Vegas Strip this weekend audience members watched him or as a circus a late performer fell from the so called of death. He's in the hospital tonight in just days after the company was hit with fines after another performer fell to her death. There are growing questions about safety
Cirque du Soleil and MGM Ordered to Pay Fines for Performer's Death
shocking cirque du soleil tragedy. When a young performer ..... wrong and as david wright reports, cirque du soleil and the cass seen know will pay a ..... guillot-guyard plunged to her death. Today cirque du soleil was ordered to pay more than $30
Kathleen Sebelius Addresses the Problems With Obamacare Website
who have insurance that works, you can keep it. George? Jim, thanks very much. Now a new twist in that shocking cirque du soleil tragedy. When a young performer and mom plunge 100 feet.
Mysterious Death at Cirque Du Soleil
Now back here at home what happened at cirque du soleil . Millions of families attend their shows every year including those in las vegas. But this weekend a tragic death of an acrobat
Cirque Du Soleil Performer Plunges to Her Death
to that fatal ACCIDENT AT THE CIRQUE du SOLEIL In las vegas. A veteran performer ..... where she had fallen. Reporter: Cirque du soleil seen here in video provided by ..... devastated WITH THIS NEWS" SAYS CIRQUE du Soleil 's founder. The safety measures
Cirque Du Soleil : Fatal Accident
vegas. The high wire act gone terribly wrong as hundreds watched. A member of the celebrated cirque du soleil troupe has lost her life after a fall here's abc's gio benitez. Reporter: The 31-year-old performer fell 50 feet during
Germs at the Grocery Store
always say to you, keep your hand off the bannisters. Off everything. Off of everything. My own family is like a CIRQUE du SOLEIL ACT. Now it's father and son in a germophobic showdown. Oh. Oh. Losing your fruit. Oh, I -- I can't touch
'Arbitrage' Star Susan Sarandon Dishes on Busy Year
And the fun of it is, everyone plays different genders and races in different time periods. So, it's kind of a cirque du soleil . At one point, I say our lives are not our own, from moon to tomb, every act of kindness or crime bursts your
'GMA' World Records: Cirque Du Soleil's Attempt
World-famous acrobats attempt to break three Guinness World Records on "GMA."
Cirque Du Soleil Flips to Michael Jackson on 'GMA'
Michael Jackson his claim that because we are getting ready for a dazzling dominate in. Michael Jackson's music an amazing acrobatics. the celebrating the King of Pop its latest extravaganza. And this morning all of us get a free front row seat for the performs. Let's bring in artistic director and
Training for Cirque du Soleil
A look at how performers eat and exercise to maintain those stong physiques.
The Red Velvet Workout
Jen James on how to get fit with a Cirque du Soleil -style workout.
Cirque du Soleil Remixes Michael Jackson
Michael Jackson's musical legacy continues to grow more than two years since the king of pop's Jackson's music inspired the new circus LA show Michael Jackson the immortal world war here's your first listen to one of the songs from the soundtrack immortal next.
From Street Performer to Billionaire
Part 1: Guy Laliberte, founder of Cirque du Soleil , was a clown with a dream.
Michael Jackson's Music, Cirque's Magic
Behind Cirque du Soleil's latest hit with Cirque founder Guy Laliberte.
Michael Jackson's Music Opens New Cirque Du Soleil
The music of Michael Jackson and mesmerizing a circus so lay the show is just opened in Motown. Right where it all began for the Jackson 5 handgun that's in droves now for a backstage look at this doesn't this morning again. That's right I'm back again. The artists of circus so have have put
Cirque du Soleil Tribute to Michael Jackson: 'GMA' Pop News Heat Index
The King of Pop gets a high-wire treatment from the Canadian circus company.
Cocooning: The Hot New Fitness Craze
Cameron Mathison tries this anti-gravity yoga with a Cirque du Soleil twist.
'Cirque du Soleil' Premieres Latest Creation
Lara Spencer goes behind the scenes of new show, inside "The Wheel of Death."
Welcome to 'Wintuk'
"Wintuk" artist talks about the Cirque du Soleil show.
The Cast of 'Wintuk' Performs for 'GMA'
Cirque du Soleil's tribute to winter is in its final season.
Cirque du Soleil Donates Coats
Time now for our warm coats and warm hearts comes drive today's come from the cast of surface a magical show wins happen. Quinton is the story of a young boy who wanted to bring snow who has here we have well over. There is still not Going to read It is the common they're putting all the getting an
High-Flying Workout
How to stay fit Cirque du Soleil style.
Giving to Charity With Cirque du Soleil
Winds up this show that was so cool to let us come on save them last year is here this morning because they wanted to contribute to the coat drive Jamie stop stop Boy from winter and obviously because you know he's a lot of time in your cold winter He knew this was an important thing tell me how
Backstage at Cirque's 'Wintuk'
A sneak peek to the extreme acrobatics of Cirque du Soleil's newest project.
Backstage at Cirque's 'Wintuk'
A sneak peek to the extreme acrobatics of Cirque du Soleil's newest project.
Flying High with Cirque du Soleil
ABC's many Castro got a taste of the highlight. Trading at her whether posted GMA for some high flying on inspiring moves but the performers of still delirium. ABC's Chris Klein has the details. Flip think big thing. Make up lots of makeup and of course don't forget the hair it would be enough to
Cirque du Soleil's Delirium
The world famous Cirque du Soleil performs "Desejo" from its current show.
All She Needs Is Love
A behind-the-scenes look at Cirque du Soleil , Beatles style.


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text: "When I started to plan the upcoming review schedule for APH Networks early last month, the influx of new network media players onto the market really caught my attention. Providing more digital media integration with your living room audio/video equipment than ever before, long gone are the days when we were restricted to watching certain videos on our computers only, or swapping a bunch of CDs every time you wanted to listen to those songs on the big system. Last month, we reviewed the Patriot Box Office network media player, which delivered excellent media compatibility for a very low price of admission, but failed to provide the kind of experience users would come to expect for a home entertainment device. Inevitably, there are compromises due to its cost. At the same time, I also began testing QNAP's NMP-1000 network media player. QNAP is known for making absolutely brilliant network appliances in both performance and reliability, such as the QNAP TS-439 Pro network attached storage system we examined back in September last year. But here's the thing: The QNAP NMP-1000 retails for $400 at press time — effectively four times the price of products such as Asus' O!Play and the Patriot Box Office as aforementioned. It is probably no surprise that you are wondering at this point what makes the NMP-1000 so much more expensive than other products that carry out pretty much the same tasks. And you know what? I was asking the same question before I got my hands on these products as well, haha. Is the QNAP NMP-1000 truly the ultimate, no compromise, fully featured high performance network appliance with multimedia features for the home user to justify its price tag, or will it fail to hold its own against the competition? To answer all these questions and address everything else in a detailed and thorough manner, well, let me present to you this week's review!"


text:
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Fastpitch Coach: Q&A
Connie Clark, Head Softball Coach, University of Texas.
Overall won-lost record at present position: 45-17
Previous Softball Head or assistant softball coaching positions: Assistant coach, Florida State, five years.
Other accomplishments: Won national championship in 1986 as a player at Cal State Fullerton. Assistant coach three years at Women's College World Series, head coach one year at WCWS (Texas, 1998).
Undergraduate Alma Mater and year graduated: Cal State Fullerton, 1987.
Postgraduate Alma Mater: Florida State University, 1994.
Softball playing career highlights: Three-time national champions, Broderick Award winner, 1987.
Q: When did you know you wanted to coach fastpitch softball and how did you get started?
CC: I knew once I began working clinics at CSUF. JoAnne Graf called me and I was lucky enough to be offered the FSU job at a young age.
Q: Who are some of the coaches and non-coaches you learned the most from and what did you learn?
CC: My pitching coach, Dave Smith, taught me to be more assertive and a little mean. My parents taught me persistence.
Q: What do you think you do best as a coach?
CC: I am organized, which allows for more production in several areas. I respect opinions and input from my staff and players.
Q: What would you change, if anything, about the recruiting process?
CC: Recruits should trade places with college coaches so they might understand our decisions.
Q: If there is one rule or procedure change you would like to see your national governing body adopt, what would it be?
CC: That we (NCAA) could oversee the olympic process instead of ASA.
Q: When recruiting, what's the first thing you look for in a player? What's the second thing?
CC: First, does she fit our specific needs for position, student and type of personality? Second, athleticism, arm strength and foot speed.
Q: What makes for a successful season?
CC: Fulfilling potential of your specific group for that given year.
Q: What do you think was the best coaching job you ever did?
CC: Splitting pitchers in a championship game, which allowed us to win the title.
Q: What was your greatest moment as a coach?
CC: Each time I see someone "get it" or execute something you just taught them.
Q: What was your worst moment as a coach?
CC: Not fulfilling potential in a team that should have gone farther.
Q: What is funniest/strangest/most memorable experience you and your team have had on the road?
CC: We have had several, but probably the time I didn't get my suitcase and the team put together a very funny care package and brought it to my hotel room. We laughed at the clothes they had me put on and we stayed up a while and told jokes and laughed.
Q: What do you love most about coaching?
CC: The rapport you build with the team and individuals. Seeing athletes "grow up" during their college career.
Q: What do you love least about coaching?
CC: Very time-consuming. I am married to my job.
Q: Please complete this sentence: My coaching career has been successful if the majority of my players_____________.
CC: Fulfill their potential as athletes and as people.
Q: Who was the best player (position or pitcher) you've ever coached against?
CC: Jennifer Lizama, Nebraska, second base. She competes every single pitch, intense.
Q: Which is the best team you've ever coached against ?
CC: Arizona in 1995. They were tough to pitch to.
Q: If you could go anywhere in the world for a week, all expenses paid, where would you go?
CC: Somewhere with a beach or water.
Q: What haven't you done yet in your life that you still want to do?
CC: Win a national championship as a coach. Do something completely out of the coaching arena.
Q: What advice would you give to young people who want to coach softball?
CC: Be a graduate assistant, student assistant or a volunteer to get a true feel for it all.
Q: If you weren't coaching softball, what would you be doing?
CC: Advertising, interior design.
Q: What is your favorite movie?
CC: Against All Odds, Patch Adams.
Q: What is your favorite music?
CC: Old rock and roll, most of it.
Q: What is your favorite food?
CC: Italian.