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Feb 7, 2010
Should LEGO make sure you can build everything?
A number of folks seem "cheated" or upset that you can't build the same models with the 1.0 kit as you can with the 2.0. Or the reverse ("we want a 2.0 to 1.0 backwards compatibility upgrade"). Or they complain that LEGO should really offer a "parts pack" that allows owners of just the 1.0/2.0 kit to build all the robots in a particular book (a very common comment).
I'm not saying "why do you want this" - that's pretty obvious (I'd love it as well). I'm not asking if this is financially viable or workable in terms of production and stock issues (what I know about those factors wouldn't fill a 2x4 brick). I'm asking "why do users seem to feel entitled to this, and repeatedly demand this?".
It's funny to me, as this seems to come up again & again in discussions on the NXT set - people commenting that "they don't have the pieces they need", or that "you can't build X using just this one set", and often stating that that's a real failing on LEGO's part. The thing I find funny about this is you don't find it anywhere else in the LEGO world. I don't know anybody who bought a single Star Wars set, and then complained that you couldn't build other Star Wars sets from it. Or even that the larger sets in theme (say, one of the larger Rock Raiders sets) should have the extra pieces needed to build a number of the smaller sets in a theme (or even cross-theme). That actually seems to work just fine with consumers of any other LEGO set. And (to me!) the idea that LEGO should design their set contents in such a way as to allow the consumer to build the huge number of user-built models out there (or even figure out which ones are "most desired"... when those trgets literally change month by month or faster) seems irrational. Yey I've heard at least some folks advocate it.
It used to be the question of "Where are the extra pieces?" was answered "In Other Sets"... and that been that way for a very long time now. Of course, it's not the only answer. The LEGO community realized that to build what they wanted, they needed more parts... so you bought more sets. Not sets designated as "with this set you can also construct X, Y, & Z", but as parts - just spare parts. Not content with that, people began selling parts they didn't need from sets they had bought for a couple of special hard-to-find pieces... and Bricklink was born. So it's not like there's not alternatives (tried and true ones at that).
So I guess the question here is "what's different?" Why are these assumptions, that previous consumer have purchased LEGO under for years, not assumed by the Mindstorms consumer? Should they be? Or is there something fundementally different about Mindstorms users and therefore the way the set should be marketed and configured?
15 comments:
- timropp said...
The difference with NXT is that they kept the NXT name and average people (aka non-AFOL types) don't understand that there have been two different NXT sets with different parts. They buy a book or see a model online that says you can build it with just the base NXT set and don't realize that it means NXT 1.0, not their newer set. Lego should have used a different name for the set or something to help with the confusion, since there is far more info out there (sites like nxtprograms.com, books, etc) for NXT than you find specific directions for other Lego sets.
- Feb 7, 2010, 2:53:00 AM
- James Floyd Kelly (Jim) said...
Very good point, Brian, about the Star Wars sets... I certainly wouldn't expect to be able to build an X-Wing from the Millennium Falcon set.
- Feb 7, 2010, 3:10:00 AM
- L3G0-Bots Lady (;-p) LEG0Bot-Gee a.k.a. V.Greene said...
Hey folks, SO... there are different elements in kit 1.0 & 2.0, there are unique and different elements in most of the LEGO kits – that's what makes the kits interesting – a new element to work with; and I wouldn't be surprised if that isn't part of LEGO's marketing plan (smile). For those who might not know, the Educational NXT kit is different from the Consumer 1.0 kit, which was cooler; so a Resource kit $80. was put together to offer the "cool" and most often used elements to Edu kit. Should LEGO offer a resource/supplementary kit to the Consumer 1.0 containing the new elements of the 2.0 and vice versa? Perhaps it would be nice… However, it is kind of sad that people get upset, because they can't build a model EXACTLY the way it is in a book. TRUE LEGO builders are supposed to be CREATIVE! IMPROVISE!! Come up with something slightly different, maybe better. To me, that's the joy of building…
- Feb 7, 2010, 4:05:00 AM
- rick-sam said...
I don't know, it seems kind of obvious to me. The NXT sets require an expensive NXT to use them. Why should you have to buy a new one when a perfectly good one is sitting right there.
Sure, it's handy that the kit comes with the NXT and parts but there could be a parts only kit too for those who don't need or can't afford a second NXT.
The Emerald Night was at one time available both ways with the power functions and without. No reason the NXT can't be the same.
- Feb 7, 2010, 4:07:00 AM
- Mom said...
For us it's a matter of cost and timing. At $200, it burns me that I have to hunt and pay for additional pieces for something LEGO promotes. (Third party books, blogs and web resources aside).
I bought a 2.0 set at Christmas, yet there are no similar books coming out for it as there were for 1.0. I think I saw one coming out later this month, another in March and one in May. All the library books he checked out, all the books at the bookstore weren't what he could use.
He's very disheartened at this point.
I realize one can adapt and modify, but he's barely 10 and needs to do the basics.
- Feb 7, 2010, 4:20:00 AM
- nxt-projects said...
I think these are valid arguments. It would be difficult for lego to achieve full compatibility over all the time. So the way it is, is fine for me. Though I think the naming / book issue is a got point. Not least this discussion helps to be aware of it.
That's why I like your blog – thanks!
- Feb 7, 2010, 4:24:00 AM
- Andy Dannelley said...
I think the difference is in a mindset. When folks buy a LEGO set (Star Wars, Technic, whatever) they know what models they are going to be able to build. They frequently see an A model and a B model. They build the A model and the B model then put the parts n the bin.
With NXT, LEGO advertises that you can build four (4) main models (already 2 more than a traditional set) and if you use your imagination you can build much more. But folks read several Internet websites and and books saying you can build all their wonderful things with one NXT kit. The consumer doesn't know that there are 2 NXT sets and if they do, they do not know the difference between NXT 1.0 and 2.0. Remember, this is not LEGO advertising all these things that folks can build, this is coming from third parties. Web-sites, discussion boards, books and other places.
It is still my contention that any NXT set (1.0 or 2.0) is just a starter set, and if you want to build more and bigger you are going to have to get more parts.
LEGO clearly states what you can build with the NXT 1.0 or 2.0 so I do not believe LEGO has done any misrepresentation here.
This seems to be the perfect storm of lack of information and old information that is present and causing the difficulties.
Just MHO, YMMV
Andy D
- Feb 7, 2010, 1:13:00 PM
- Tim said...
Here's another thing to look at: if there isn't an NXT 1.0 to 2.0 upgrade, then you have to buy an NXT 2.0 kit. Then you have two NXT's and can build two versions of Alpha Rex at the same time!
- Feb 7, 2010, 11:14:00 PM
- Pe-ads said...
I agree with Tim; the difference between the two is not obvious enough for the average consumer. Most of the authors have asked their publishers to put 'not compatible with 2.0' on their books, but that's only half the problem . I really think LEGO should put a notice on the boxes to say that it's not the same as 1.0. That means if people don't notice the warning on either the book or the kit, then it's their fault, not LEGO's/the author's.
Also, with all due respect, I find it slightly annoying that some people moan about the fact that there are 'no books for NXT 2.0!' There were absolutely zero books for NXT 1.0 when it came out!
- Feb 8, 2010, 4:26:00 AM
- James Floyd Kelly (Jim) said...
Pe-ads is correct - when the 1.0 came out, it was about 3 or 4 months before the first NXT book came out... and even more months before a more regular stream of books became available...
I can't guarantee there'll be as many books for 2.0 as there were for 1.0 (many many reasons), but there are some more being planned. 2.0 owners will need to be patient a bit longer...
- Feb 8, 2010, 5:10:00 AM
- Brian Davis said...
Actually, it's one of the reasons I don't see a good reason to write another book... when the kit changes (& it will), if the readership expects a recipe book... then you have to come up with a whole bunch of new recipes. Teach people how to cook, and they'll make a meal with whatever they have at hand. It certainly does make it far tougher to sell books in the long run, as your goal is to make folks self-sufficient.
A great example of this is the book "Building Robots With Lego Mindstorms" by the Ferrari brothers & Ralph Hempel, or Yoshihito Isogawa-san's books. These don't have detailed plans... they don't have finished robots... they don't have code examples written in the current language de jour (or any language, for that matter)... yet they are the books that I pull off the shelf time and time again.
It doesn't matter if you're using NXT 1.0, 2.0, or the RCX - the books are largely part-independent.
- Feb 8, 2010, 1:04:00 PM
- Fay Rhodes said...
While I feel the pain of parents like Mom, I don't think it's the responsibility of the LEGO company to provide any more models than those offered on the box. It would be better if they did, but we can't expect it.
Then, there is the never-ending debate over whether we are encouraging laziness by offering building instructions at all. My position in that debate is that some of us need to see working examples of mechanisms and programs---that includes 10-year-olds and their parents or teachers---to "get" the idea.
I've had people suggest that my Zoo book 1) makes people lazy 2) inspires people, and 3) defrauds them (because they need additional parts). Some love it; some hate it. There really is no winning.
I find the books Brian mentioned are not particularly helpful to me, for various reasons. But that is me. I learn best by watching a mechanism in action. (Thank you to all who put videos on YouTube.)
Mom, don't forget to check out the free building instructions for some very cool 2.0 models in the news section of the MINDSTORMS website. Also, check out what Dave Parker is offering at nxtprograms.com.
- Feb 8, 2010, 6:07:00 PM
- Andy Dannelley said...
Both Fay and Brian have good points.
Brian's point that we need books like "Building Robots With Lego Mindstorms" by the Ferrari brothers & Ralph Hempel is well taken. I also believe we do need more books like this that teach basics without getting too mired down in specific constructions. I have and really like "Building Robots With Lego Mindstorms", and right now I'm looking forward to "The Art of NXT-G Programming" by Terry Griffin as I believe it has the potential to help in this area as well.
Fay's point that many people need examples to learn how things work so better understand the process is also very valid. I believe that the learn by doing is a very powerful teaching method.
In my mind it is not an either-or, it is both. We need both types of books and other instruction to become better at whatever we do.
Did your math book just have theory? All the math books I ever used also had detailed examples so as to teach a concept, then you are presented with problems that help you to apply those concepts. I do not believe we are all born with the ability to abstract and do things "out of the box" (including building things with NXT), some of us need a little extra information and help.
As I tell my students that it takes time to learn the technology associated with the course. We do not all have the same experiences with computers and what not, we all needed to learn how to do things at one time. I provide examples to help my students learn, so that they can then do the assignments. I teach a hybrid distance education class. Many professors do not believe that they need to give their students any instruction on how to use the course management technology. I devote one full lecture to teaching the technology, along with hands experience and detailed examples so the students can learn by doing. The distance education specialist tells me that the students in my classes have fewer difficulties with the technology than any other class on campus. To me this proves that examples, very detailed examples are a very valid teaching method.
With NXT, I believe that examples, very detailed examples are very useful. Dave Parker (NXTprograms) does a very good job of providing examples and challenges. I have read books by Jim (Kelly) that also provide good examples and challenges to help people grow through examples and experience. But we also need books that help with general knowledge on the topic (like the one's Brian discussed).
This has turned into a very interesting topic, lots of opinions, and lots of information that should help both the old-timers as well as those new to NXT to understand what is happening in the world of NXT confusion.
This reply got way, way too long. Maybe it should have been a post instead.
- Feb 9, 2010, 2:34:00 AM
- Clinton said...
I think Mindstorms is different. Instead of posting a really long comment, I've put up my thoughts here.
- Feb 10, 2010, 6:31:00 AM
- Jason said...
Many good points have been made in the replies to this question. Here are a couple of observations I would like to add:
1. Supply and demand - let the free market work (and it already is working). Whether the Lego group provides "conversion" kits (1.0 to 2.0 and/or vice versa) nothing prevents someone else from providing the kits if there is enough demand. (FYI check out Brian Davis' website nxtprograms.com for a link to an independent supplier that provides both flavors of conversion kits)
2. The confusion and differences between 1.0 and 2.0 go beyond the bricks and sensors. There are differences in the programming language as well. For example, I just recently discovered that the 2.0 version performs floating point math! That is a subtlety I hadn't discovered while checking out various NXT web resources. This single difference can cause unsuspecting people a lot of confusion especially since so much of the 1.0 literature focuses on getting around the limitations of integer only math. It also creates new "problems" (aka challenges) for 2.0 owners to tackle. (i.e. how do you implement an x mod y function using the 2.0 environment)
My suggestion for the Lego group is to provide some detailed descriptions of the differences between the various sets on their website. This is a common practice in the software community where customers have come to expect being able to understand what has changed between releases of a product. In general, a better educated consumer makes for a happier consumer which then leads to repeat business.
Finally, I think Mindstorms customers' expectations are different (good or bad) because the Mindstorms Lego product is a unique hybrid Lego product. It combines hardware (bricks, CPU, sensors) and software. Therefore, customers' expectations will naturally draw from both domains.
- Feb 10, 2010, 10:44:00 AM


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I'm looking at a Mac Mini for my new home office. The needs aren't huge, music production, photo editing, maybe a LITTLE video but nothing huge. My budget is £500, so for that I could get the entry level Mac Mini (http://store.apple.c...B/A&step=config)
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Can I ask without bias (and any "Get a windows PC / linux / whatever will simply be reported") which is most suitable and moreover why? I mean, is a Hackintosh likely to have issues with software updates?
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Game wardens: Record book deer was taken illegallyBy Patrick McArdle
STAFF WRITER | January 30,2013Vermont Big Game Trophy Club Photo
These antlers are from a huge buck shot in Stamford one day after the November deer season ended.STAMFORD The Vermont Fish and Wildlife Department had good news and bad news for a local hunter in December.
The good news was that the large, trophy-antlered whitetail buck that Jim Smith, 47, of Stamford, had harvested in Stamford was the largest taken in Vermont in more than 20 years.
The bad news was that the buck was taken a day after the 2012 rifle season ended so instead of congratulations, Smith is now facing criminal charges for which he is scheduled to be arraigned in Bennington criminal court Feb. 11.
In a press release, officials with the department said someone had witnessed Smith removing the 10-point buck from the woods Nov. 26 and then tipped them off.
There was no record of the deer being reported so Vermont Game Wardens Richard Watkin, Kelly Price and David Taddei conducted an investigation.
During an interview Dec. 19, Smith admitted to killing the deer the day after rifle season ended but said he had mistakenly believed the season was still open, wardens said. The antlers, meat and hide were seized by wardens.
Smith has been cited to appear in court for taking a deer during the closed season. If convicted, he could be sentenced to 60 days in prison, lose his right to hunt, fish and trap in Vermont for up to three years and be fined up to $3,000.
Curtis Smiley, a lieutenant with the Fish and Wildlifes enforcement division, and president of the Vermont Big Game Trophy Club, said the buck would have boasted a Boone and Crockett Club score of 165 2/8 gross. The Boone and Crockett Club is a national conservation organization, the keeper of North American big game records and the creators of a standardized scoring system.
According to Keith Balfourd, B&C marketing director, the score would make it the fifth- or sixth-largest buck reported from Vermont since the scoring system began almost 100 years ago.
The minimum score to make the B&C Awards book is 160 inches. To make the B&Cs Records of North American Big Game record book, the antlers must score 170 inches.
Vermont doesnt historically produce big-racked, white-tailed deer and there are only 13 in Boone and Crocketts record books, Balfourd said.
Watkin said he agreed with the characterization that the deer would have been a once in a lifetime deer especially in Vermont.
The buck could still be entered into the record books if its submitted by the state, but the name of the hunter, if he is convicted of taking the deer illegally, will not appear. The value of listing the buck would be for tracking the deer population and conservation efforts in Bennington County.
Balfourd said the people of Bennington County should take some pride in their management of public land because a deer would not grow so large unless the habitat was being well-managed.
Officials with Fish & Wildlifes enforcement division said they couldnt provide much more information about the incident because it is a pending criminal matter but Chief Warden Col. David LeCours said on Tuesday there was no evidence that any other illegal means of taking game, such as using a spotlight or shooting from the road, was involved in the alleged incident.
LeCours said Smith didnt have any previous violations on his hunting record.
According to LeCours, most hunters are very aware of when the hunting season begins and ends.
Anyone who hunts deer any length of time in Vermont for rifle deer hunting knows that the season ends on the Sunday after Thanksgiving day as it did this year, he said.
State game wardens asked that people who see or hear activity that might be illegal, call their local Vermont State Police barracks or call Operation Game Thief at 800-752-5378.
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Posted 26 January 2013 - 09:21
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Posted 26 January 2013 - 10:17
As someone who has to read and manage a lot of email in my inbox, i'd like to suggest;
1. don't do it. please send in nice clean text that I can view as I like. I constantly get people sending me emails in weird and wacky ways with things like HTML that is totally broken to the point I can't strip it out or rtf.. I had one company that sent everything as a PDF attachment wtf is that about?!. I'd just like a plain text email that I can assign my own fonts to , not size 8px red on orange background or size 120px klingon superscript. I know this propbalby doens't apply to you, but I do prefer my emails to be clean.
2. Yeah, don't do that either. I hate it when I have to wait several minutes for new mail to finish downloading because someone decided it'd be great to send screenshots of issues, lots of screen shot and attachthem to the email... or the actual email as a PDF file.. please use links to anything you want the recepiant to view where possible, please.
Not sure what you're actually looking for with updated features. Email is, or rather should be pretty basic and feature set by now.
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Laos - Along the Mythical Mekong
|Overview • Detailed Itinerary • FAQ's • Testimonials • BOOK NOW
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Day 1: Arrive in Vientiane, Laos
Upon arrival at Vientiane Airport, you are met by our representative and transferred to our hotel. Dinner and the group orientation this evening.
Day 2: Vientiane Sites
We have a morning tour in the Laotian capital, Vientiane, located on the banks of the Mekong River. Founded in 1563, Vientiane is known as the City of the Moon and is known for its great sunsets, riverside restaurants and well-preserved colonial architecture.
Day 3: Van Vieng
We drive to Van Vieng, famous for its limestone cliffs that give the landscape a similar look to China's 'Guilin' region. Located on the Nam Song River.
Day 4: Stunning scenery to Phonsaven
Today, we drive to Phonsavan, along one of the most beautiful routes in Laos. Driving through the mountainous region, we make stops to explore villages and take in the scenery from various viewpoints. Time permitting, we will visit an organic fair trade silk farm. We spend the night in Phonsavan.
Day 5: Plain of Jars (UNESCO)
We spend the day exploring the Plain of Jars, one of the mysteries of the archeological world. The site has been placed on UNESCO's Tentative List, which means it is presently the focus of international Safeguarding Campaigns. Hundreds of massive clay and stone jars litter the landscape of the area, some of which are as large as 6 tonnes! There are over 60 different site locations of the jars, with some sites having over 200 jars. It is not known what the jars were used for; many theories abound, including that they may have been used as wine holders or for funerary urns. It is known that the jars are around 2,000 years old.
Day 6: To Sam Nuea
We have an early start for our drive to Viengxay through scenic countryside. Our destination is close to the Vieng Xai Caves used as the headquarters of the Pathet Lao Revolutionary Movement during the Indochina war.
Day 7: The fascinating Caves of Viengxay
In an area dominated by limestone cliffs close to the Vietnam border, we will explore the caves used as a shelter for 20,000 people during the war. Visit schools, hospitals and even markets inside the caves.
Day 8: Northern Heritage Route to Nong Khiew
We have an early start to drive the "Northern Heritage" route to Nong Khiew. Our journey takes us through stunning mountains in an area less visited by tourists. Our journey takes us through local villages including Ban Saleuy which is renown for it's weaving.
Day 9: Nong Khiew Village Life
Today we can enjoy Nong Khiew village life as we can do an easier hike visiting villages, a local school and finish with a long tail boat ride back to town. Alternatively, enjoy an optional "100 Waterfalls" hike for those who crave a very challenging (optional) hike.
Day 10: To Luang Prabang (UNESCO)
We start in Nong Khiew and travel by road to Pak Ou Village. Board a boat and cross the Mekong to visit the holy Pak Ou Caves. Continue downstream by boat.
Day 11: Temples of Luang Prabang
Today, we have a half-day walking tour of the old capital, Luang Prabang. This town is in a beautiful mountain setting at the confluence of the Mekong and Nam Khan Rivers. One of the most romantic cities in Southeast Asia, Luang Prabang is a delightful place to explore on foot.
Day 12: Kuang Sy Waterfall, K'hmu Villages
Early this morning we have an optional trip to see the monks receiving alms, followed by the colorful morning market. We return to the hotel for breakfast. After breakfast we visit a small ethnology museum before heading to Kuang Si Waterfall. Enroute we visit a K'hmu ethnic village to learn about their culture. On our return to Luang Prabang, we will visit the village of Xang Khong to see traditional Sa paper being made and a small weaving workshop.
Day 13: Elephant Village Sanctuary
Today is a full day of Elephant riding and trekking. Just 15 km outside of Luang Prabang, this is an easy day tour combining a few highlights that includes village visits and soft hiking into beautiful countryside and the magnificent Tad Sae Waterfall.
Day 14: Fly to Pakse
After breakfast transfer to the airport for your flight to Pakse. Upon arrival visit Wat Luang the biggest and most beautiful temple in Pakse, and home to the Buddhist Monk School. Also visit Wat Phabad the oldest temple of Pakse. It is believed to have a Buddha Footprint, from which its name is derived. After lunch visit Ban Keosamphanh, a former French army camp, that has the most beautiful green rice fields and is home to the oldest market in the area.
Day 15: Start 3 day Mekong River Cruise, Pre-Angkorian Ruins of Wat Phou
After meeting at the Sinouk Coffee House in central Pakse at 9:30am, we transfer you to a long tail riverboat for your 2.5 hour journey to Champassak. Upon arrival at the Vat Phou boat, we help you to your cabins to unpack then serve lunch on deck. The highlight of the afternoon is the Vat Phou ruins - the majestic pre-Angkorian 10th century temple complex and boat's namesake. You have time to visit the museum at the ruins site, walk up to the highest temple and take as many photos as you would like. As dusk falls, we transfer you back to the Vat Phou boat for a chance to enjoy the tropical sunset on the deck. Dinner is served on board, while the boat docks for the night alongside a remote Laotian village.
Day 16: Huei Thamo, Oum Muong Temple, Khong Island
Breakfast is on board as we set sail for the village of Huei Thamo. This is a small village a few minutes walk away from the mysterious hidden forest temple of Oum Muong. Afterwards we rejoin the boat to continue our cruise southwards. Lunch is on the deck, while leisurely sailing closer to the wild paradise of the "4,000 Islands" Late afternoon we disembark from the boat to walk through Ban Deua Tia, a small Laotian Village where the traditional way of life has not changed in centuries. Our day's cruise finishes at the most northern tip of Don Khong, the largest inhabited island in the river archipelago. After dinner, the evening is yours to relax and enjoy.
Day 17: Don Khone, Pha Pheng Waterfall, Pakse
While you breakfast on the deck, the Vat Phou boat cruises the Mekong to the small village of Ban Veuthong, where you board a small boat to meander among the 4,000 Islands to Khone Island. You will visit the old French railway and walk across the bridge that links Khone and Det Islands. We continue on the boat back to the mainland for lunch at a local restaurant in a small fishing village, Xieng Di, on the banks of the Mekong. A bus transfers you to the historically significant Pha Pheng waterfall, "the Niagara of the East", close to the Cambodian border. We end our cruise with a small boat transfer to Pakse, where we will have our farewell dinner.
Day 18: Depart Pakse
After breakfast, we transfer to Pakse Airport for our international flights homeward or join our extension to Angkor Wat.
1-800-741-7956 North America • 0808-234-1714 United Kingdom • 416-588-5000 Worldwide


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text: look at WFs bio for his Havok character- its a name of one of his wrestling moves. Then Youtube Austrian Death Machine- thats who he got the name from. The band does songs based on Arnold movies- terminator, kindergraden cop, total recall, predator etc. Lol. Get to tha Chopper is my fav


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KosherEye Giveaway
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Study of Intratumoral Hypoxia Using Pre-operative Administration of Pimonidazole
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This study involves the intravenous (given by vein) administration of a hypoxia marker, pimonidazole hydrochloride, approximately 24 hours before surgery for pancreatic tumor in order to identify areas of lower oxygen content on samples of your tumour.
Pancreatic Cancer
Drug: Pimonidazole hydrochloride
|Study Type:
|Official Title:
|A Clinical Trial of Intratumoral Hypoxia and Its Biologic Correlates in Patients Undergoing Surgical Resection of Localized Pancreatic Cancer, Using Pre-operative Administration of the Hypoxia Marker Pimonidazole.
- characterization of intratumoral hypoxia in pancreatic cancer [ Time Frame: 5 Years ] [ Designated as safety issue: No ]estimation of tumoral hypoxic fraction by immunodetection of pimonidazole adducts.
- correlation of intratumoral hypoxia with patient survival rate [ Time Frame: 5 Years ] [ Designated as safety issue: No ]evaluation of correlation of tumoral hypoxia with disease-free survival using Cox proportional hazards analysis
- correlation of hypoxia with molecular markers [ Time Frame: 5 Years ] [ Designated as safety issue: No ]colocalization of molecular markers using immunofluorescence microscopy: Stem-cell like populations markers of EMT Endogenous markers of hypoxia (HIF1a, CAIX)
- to assess utility of circulating osteopontin and miR-210 for identifying hypoxia [ Time Frame: 5 Years ] [ Designated as safety issue: No ]correlation of tumoral hypoxic fraction with plasma levels of osteopontin and miR-210
Biospecimen Retention: Samples With DNA
Pancreatic Tumor biopsy and blood samples.
|Estimated Enrollment:
|Study Start Date:
|October 2010
|Estimated Primary Completion Date:
|October 2015 (Final data collection date for primary outcome measure)
|Assigned Interventions
Drug: Pimonidazole hydrochloride
Pimonidazole is a 2-nitroimidazole that is selectively reduced and covalently binds to intracellular macromolecules in areas of hypoxia (by definition, p02 <= 10mm Hg) within normal and tumour tissue. Pimonidazole adducts can then be detected by immunolabelling techniques (microscopy, ELISA, flow cytometry etc). In this study, pimonidazole will be administered intravenously as a one time dose of 0.5gm/m2 (with a maximum dose of 1gm) 24hrs prior to surgery. Since the drug has a half-life of approximately 5 hrs, this time-frame ensures low circulating levels at the time of surgery and therefore reduces the confounding effects of surgical hypoxia on tumour analysis.
Other Name: Hypoxyprobe-1
Detailed Description:
This study involves the intravenous (given by vein) administration of a hypoxia marker, pimonidazole hydrochloride, approximately 24 hours before surgery for pancreatic tumor in order to identify areas of lower oxygen content on samples of your tumour.
Pimonidazole is a drug that, when given intravenously, will attach to areas in the tumour that is low in oxygen. When this happens, the areas that are low in oxygen can be more easily found and studied.
We will collect tumour samples from about 100 patients to study hypoxia and other biologic processes in clinical pancreatic cancer as well as animal (mouse) models of these cancers. Since patient samples are being collected as part of the Pancreatic Cancer Genome project (designed to collect 500 patient samples) we developed this companion study to characterize patient tumours with respect to hypoxia.
|Ages Eligible for Study:
|18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
Participating in ICGC Pancreatic Cancer Genome Project.
Inclusion Criteria:
- age > 18
- provisional diagnosis of pancreatic cancer
- scheduled resection at UHN
- consented to ICGC Pancreatic Cancer Genome Project
- surgery planned for >2 days away (drug administration has to be 16-20hrs before surgery)
Exclusion Criteria:
- not participating in ICGC
- contraindications to pimonidazole (allergy)
- surgery scheduled for same or next day (not enough time to arrange for drug administration)
Please refer to this study by its ClinicalTrials.gov identifier: NCT01248637
|Contact: Neesha Dhani, MD
|416-946-4501 ext 4921
|Contact: David Hedley, MD
|416-946-4501 ext 3428
|Canada, Ontario
|Princess Margaret Hospital
|Toronto, Ontario, Canada, M5G 2M9
|Contact: Neesha Dhani, MD 416-946-4501 ext 4921 email@example.com
|Principal Investigator: David Hedley, MD
|Principal Investigator: Richard Hill, MD
|Principal Investigator:
|David Hedley, MD
|Univeristy Health Network - Princess Margaret Hospital
No publications provided
|Responsible Party:
|Dr. David Hedley, University Health Network, Toronto
|ClinicalTrials.gov Identifier:
|NCT01248637 History of Changes
|Other Study ID Numbers:
|Study First Received:
|November 24, 2010
|Last Updated:
|June 18, 2012
|Health Authority:
|Canada: Ethics Review Committee
Canada: Health Canada
Keywords provided by University Health Network, Toronto:
pancreatic cancer
pancreatic tumor
whipple's resection
Additional relevant MeSH terms:
Digestive System Diseases
Endocrine System Diseases
Pancreatic Diseases
Pancreatic Neoplasms
Digestive System Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Pharmacologic Actions
Radiation-Sensitizing Agents
Therapeutic Uses
ClinicalTrials.gov processed this record on July 07, 2015


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Welcome to FestivalFinder, the site where you'll discover the latest details on more than 2,500 music festivals in North America.
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Sac. Jazz Fest. & Jubilee 2010
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Musicians having a good time, too!


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1950-12-07 1
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'1^':"'^<^Y^<K^ " i •' i'*.,', 5r<'''f v.\v /..", /;• :; y-\ I • ^w*'i ^**\. J/!{J •'*.t/'!l.7 "•';."' );#^^9W^ ''•:.'.:;.. ':•':: v^'^'tr''::;K/;^ "*lLV.^'^.y^V 15tli YearvNo} 2&:;; •• * '*, ^BEEPpaT^ '., re' ^•#{r*. ™T TT*** Wjw W&V" '•'•'; •''•'':" -\ '"•• -.'"'• •" ''-'• •' • ''''^ ''• "•'•'.'' ''"• •'"•''• * J^ivk^ %iMK'^ ,,' <•; •', •#??:;'OZ^#^y OR?i' \ \ 14^^^ To To Go ht Groups douiicll at its Monday night in *b,e' M Building; adopted MspluiM callliig.bn the propier authorities o takel:steps to see that conditions are remedied ao that the two trage-dies which, liave oocumrect on the Long Island Rail Road' within less $han a year ape not \repeated. Ooples of the resolution are 4o be sent to *Ae organizations constituting the Council and they, in turd. will .take such action as they deem fit. "The resolutions <were presented by by Homer I. Harris and explained by Edwin- J, Freejman. TBiey were adopted on motion of Russell K tot-aling, and read as follows: "W^ hereby .declare .that the tra-gedy resulting from the two L.IJ&.R. wreaks within .the space of less than one year. In which so many of our neighbors and friends were killed _ .*.-**»»«#v- o—" '"investigations, resolutions and blame fixing are not enough and cannot take the place of "concrete action to avert further tragedies of this nature. , "Our memories must not be short. At aL cost«'iar.the excitement of great world p^blema,'ve.'muF\nrk permit=the; prcaont- impossible situ A - *:*k* •--«" '• — — , wwMWMmwwnnMHMMMMIIMMMMMMHMMMkMMk^^ Four members of the cast of "What a Life/' presented by the Masque, and Wig Club as the annual senior ptlhaey ?o»fm:nM #trh e?. »F'»r e^ep*o ?r;t»- —H igh.. .Bo l*t .oolT-Ieft *e ?**h*,Moret*e McrrMt. ?»+ «"» /w^^. ^ » - — —- » *»&. **«ww W* VYCHW & I'M play of the Freeport High 8ohMlr-hft *o (he leading rd^c of Ilchry Aldrioh, and Ba , Morrltt,, Pat BUss, /Frank O. Barry Hart* (Story on page 2) •'•; m Acdpn » i?Ken on Contracts Tdo Late For hsue of Leader '\ Irit of F^epprt* Cr^w '•We demand Izatlonif and "We .to the end . ^^^^ blym &n . . of our cooitltuexit to ^rlte. t^ie', G<>veMi(%r our "State .Genatqms and Aasem- ' - islation eneibllng theen astcattmeee bn yt oopf r loeepgger-- authority to operate and manage the railroad. * "We iirge all of our constituent organizations to write to. Congress-man Leonard W. Hall and %T J9. Sen-ato_ r_ —I.rv l-n., MT**I.v e*a ?.w. M i*ud* u Hjeirebreonetrc H, I^elunan urging Immediate action by Hie mter-6bate Oommerce Cbinr mission .forcing rnataHatlon'of .nec-essary safiety equipment on ,:the LJ.AIR. to guarantee that our pub-lic officials; do not .forget this pro-blem of the, LJ.RJR. in the press of later or greater problems. We here-by create a permanent committee of five members impbwered to co-operate with other ""— - *—^ - • By rJ^ei^^JpsephB: Taylor Bombardler^;^ApM* of Freepo^'^B^9 ^^.^'"m"' M^"B "*"'"^ ^%#&' '^ Mtpp-^*^reep6zt^I^g^ii&n'&^ •'•"'//MaroA . _,_ injlea as the B'29?.»^^ ** but well worth the: 4?4P' m fact, the sixteen, of'us wji-o nan *a «*Rv**M+ *** ™- ^" •" ^— - Dpwee on Brdadtiaat Having studied the bids submit-ted by various contractors to do the general construotion, heating anA ventilating, plumbing and/sanitary and electrical work for the new Bay* view ave. school in consultatidn with Architect prederio P. Wiederainn. of Valley Stream, the Board/of Edu-cation was to have*'taken formal ,._ an the awarding of'the con-tracts at & meeting last night. How-ever, as The Leader had to g& to press earlier in the day to make the mails for delivery today in the homes of Ks readsrs.lt is impossible to give a report of the action .taken at the meeting in this issue. However, Leo F. OlbJyn, presi-dent of the Board :J Sduoation issued a statement yesterday, in which l?e said: j . 'v . "Firm bids were' received whidh slightly exceeded the . estimatod oosL A number of alternates were' requested in the specifications whl*m the Board of Education is studying at thet present time/to determine, 'the award of,\the contracts and^if' additional funds arer, required-to do-.the'work.-*: /.,- /••.,'' ,'/, y^yV...---->-/-. VThe Board of Education : feels '"^^% ^d*^u&e*!^;* -tto*'< the. ' - - %"^ Ml^! ,, ..**, w««&wwc** v* ua wjio the "Spirit of Freeport",B-29 Surer-fortress are agreed ithat each of us will fly many times- tnad: defiance before we mee"t the equal of the hospitality we received In, that smaJl by dynamic Eastern city. The folks who.bought our bombeir treated us all like long lost sons. We arrived back here panting but mighty pleased after five ?of the fullest and mo# thrilling da)rs we've ever spent. ' '' ^" the last u was the hlla ___..... v»* ^M*&*c vm**LpiuA*f over one another changing from flying coveralls to blue uniforms just be-fore we landed. **.^***w% w*wi wilier organizations in From the time of our landing and constructive^ action designed to pre- the parade—which was probably the vent further disasters on the L, I. first and last time each of us will R.B." • ^^ ever have his own conventible — A forum on the Seniof uWzens each thing that happened seemed • Group activities' being;, conducted better than the last. Mondays and Tuesdays in the Am- The public reception, the War erican Legion- Dugout was conduct- Bond gifts, football game, dances, ed by John, P.. pejjonhe, chairman dinner parties and cocktail parties of the movement '.Mrs, L.. S. Yudin —«ach brimming with hospitality told how the group was functioning, an4 kindness—bowled, us over. Mm. Arthur. Barrfgan spoke on Its The tripe to New York were the possibilities. Mrs. ^Elizabeth F, Kel- first to most of us. We certainly en-ley told cJ the.;progr6ins of simi^ joyed meeting Mrs. Roosevelt and lar movement?;.in Nassau County were.thrilled by Miss Jinx Faulken-and the country a* large. Mrs. .Phil-, burg. Luncheon at Sardi's was won* ip Bloom appealed for those present derful, and Guy Lomlbardo and his 4ttiooh et cahTlMelAJ vat*dMhvMeaa vnaitttatgeenqti obne inogf tohffee rpeedo pblye owtr+gyahnl »zaitlon were certainly in """ ' ;\%%% ??ek York ;«$& Prayers fo in every okhe'way peace to this .. • perf onnanoe of one of Broadway . . "— *v.*.**wjr ma.:* *te m iii.^ hit shows. own good time' and the uncertain-tie? of the present .day and bring lasting peace. Everyone who agrees with these sentiments is invited; to drop into the Army headquarters any day and join in the prayers for the end of hostilities and a perm-anent peace." Holiday Season Hours Listed By Post O@c 0»»t^ A-- "- — :SB3#^X»^B^^^^ • t- "the movement. . " iSo many people'did so many An appeal fb? funds to},'provide things for us, we're all at a loss equipmenf to enable the pouncil to (to know just wliom we should thank; condupt.classes In various'subjects So :may we. just, say "thanks" in also was piade, ; ; < ..,, this story to each and. every ojie ii. Mrs/ Hornold W, B«*tin, past pres- of you who had anything to do wl^h Jdenit, presided -Jh the^abgense of the five days pf *"^-*" * ' President SainuelLyleraeL ' " honor? ' .^^ — W* ^^****#%^ Postmaster Mary Bannon uoday announced the late hours of Win-dow Service for the Christmas per-iod at the Freeport Post Office.. Parcel Post, .Registry and Stamp .Windows will be open during the following hours: Through Dec. 9/8:00 AJM. to 6:00 :M . •• ... • . . . . . . December 11 to 14, inclusive^- .!'.-.! V.' aavproud of FreepqPt'; "B?0@ Iq you have-been Jwe'can make you 7:00 A^J. to 8:00 ; December 15 to r:oo A^f* to 6:001 22, inclusive— December -33"-7:00 AJ^M. to. 6:00 'pair. '• •' , v. • • ; • . • Money order seirvie..wlll be avail-able during the hduihg.of 9:00 and •the :*he vvx y . , «* future ds . including 6aturijayB, \ ; Money order wlhd@\v #U1 . be op 22, from 9:0. •urday, . '' UniJfor sales L-C'V flJ'' •/r(: ••'X.t /^r @B™^^MBB^ S%!™! 4,y <* «. '^ 'W " ^ '^- WJ "\»" /.•^•"•yv • ^ •"*•.* * • <• ?f ;%V 'J \* - v- J-", "'I' '('' #J ,. ..__ _^ ...^. ,.,,*@*w,pM. woQ^.»a%»a" nosp&«u»y,^.''r''i'"%'-'-^..-y• -..•n o-;/m. yvfn!"i'.f-o;[r• ?,.'^ ^ C^^:wiir,^pi*sen!!.'^^vJ^^ ^^^^f^rViyy^^vZ-.'.,^- •''/}"' {•• < KiWMi* M###M?;t& ^)^3&lsol$W;^j^%iakmua3^%neet< / iThe;^v«8ohlM#Ti%^/^-SbMp9aoyp ffA '%™ ^%^^u#^I^%Sl%%eB^ j9ou*hvMain$st^;^4'%!eaM^ 9B[tedr to r^^wo^A?pres&i?»kv to after;the'ot^r druggists:J%& B*e@r rv«a-Lu'cV7wa"e?e"'d.' '^R»"s'"J ^.&I-"^-«• w zbrt!cioMi «MMHaw'«+^«* «*** *^* of Dec dudhgl the . 9Z1 on Sat-of stam 3Bt will schools Henry Vielbig Dies In Sarasdta/ Florida Friends, in Freeport have just re-ceived word of the death of Henry Vielbig,: a former Freeport resident and attorney In Sarasota, Fla;, last Friday. Mr. Vlelbig moved to Flori-da three years ago.. He was associated with Joseph ?"r?he3 and'Raymond Malone in Uie practice of law at 23 Pine st,'He was active In local politics and.a past^ Sxhalted Ruler of the Freeport Lodge of Elks. . % ?Jr, V101b*g will be among the 28 m«mlbers who have dlepl during the past year to receive recognition at the annual memorial .exercises to bo held tonijht by the Elks. For-mer. Grand, Exalted Ruler. .George I.;Hall arlil be the 'SpeaKer. .Mrs, George W. Bems will sing, Zdward F. Meaney. is chairman of the orial. commlttee^i ' "• •' • y; ,•. .Willher Heat Co., Inc., $133,984; Dierks Heating Oo., Inc.; $124,114; James % Martin, Inc., $125,742; H. Sand & Qo.? inc., $138,400; Benwihd & Co., Inc., $138,760; Cpurter & Co., Inc., $132,626, and Brutschy, Fred, Oo., Inc., $133,783, , . , : Plumbing and Bantlary-nJohn Boyd Plumbing & heating Oo,, Inc., $58,995;. Central Plumbing & Heat-ing, . I n c,, $59^)00; Rlttenhouse Plumbing, $03,840; Moriarty & Mol-ler, $04,191; MUIer-Lette»nan Oorp., $65,969, and ' Eastern -Mechanical Corp., $75,622. ' , . ' Elec tries 1—Bank Eleotrio Od., $93,- 900; Ai-c Elec*.Oonatr. Co., $M,640; .Oeeco Else. ^Opnstr. Co., $J7,930; MaiWn-Bpste'h Co., $103,980; Nager Elec. Co., Inc., $113,403, and Karter, Harry B., E. E,, $124,500. .: .. i Unity Party Meeting Call«dfor " ' '* KRX* on , ,'!V','..''*;'. ''* ^ji^llpl^g^ill^Sf^MMMmisk^ $1,S28 WasCoII^ | Jn Girl Scout Campaign Contributions to the Girl Qocuf movement in the annual;fund rais-ing^ drive., tolled $1,528.11,. William J. Margin,! jr.,, the honorary cnalr-man, knnqimced today.' This was ;the, highest lamount collected Sin recent years* he /commented. <% B^ th Mr^ Maytlp,' and' Mrs. '^Wwlidy' Mln-% nerly,\' fund •. drive ehainhan,' @^!' Dressed appreciation to; .all: whp^ assisted in:- the campaign ,^ in a%iy' fOfOW 'MaWnfd4 M^*'* ^— .*4-^V.-. *-- • '" ' ao. generously ^ • r. j,_ ..v • .-•: -.i. : ••/'<•.•.. • ,% ^• -^• ••'' '.''•< ''•''''%•'. "' -'^• •''"• '"•'••. '' T 'V'-'-' y .'' / 'f'-':"•'*'•'''•/" '•. ' " • '^'-.',"''.'• J- '•:•'.'' ' iVJ'-.V^' vA/-'J..../..y': '•' ..v.'^lJ^iliJvV.V*%'".V.:\*jt'' j%:;j\Av..v.'^!:' ;7&'»vj.^l T- ^.' .^^^V'il^^^^^^-^^:---V?'^^:"^^^ ^- -/^rr: %• ^}^r% ^ • ?^'.^:''^^^"'%'r3-l;-"-f?l"' •^•'R^'"-';'• nR\-•''?^ j •;;•.? 'AT-!;.'%:,:'• .)'.••• »%™^w.|Bli.«^^^^^
Object Description
|This is a newspaper distributed locally within Freeport and Baldwin, Long Island, New York
|Linda Toscano
|L & M Publications, P.O. Box 312, 30 South Ocean Avenue, Suite 204, Freeport, New York 11520.;
|Nicolas Toscano, Michele Swersey, Joan Delaney.
|Freeport Memorial Liobrary
|United States
|Newspapers are Public Domain before 1 March 1989; and Digital Rights after that date transferred to Freeport Memorial Library by L & M Publications.;
|1950-12-07 1
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Far too long has the subject of Satanic magic and philosophy been written down by wild-eyed journalists of the right-hand path.
–Anton Szandor LaVey, The Satanic Bible.
While not a "wild-eyed journalist of the right-hand path" (whether defined in Tantric, Blavatskian or newage terms), I have, over the past few months, shared some rather amusing sensationalist news stories written by those who are. I thought it only fair to take the time to write a short piece on "real" Satanism and go beyond highlighting some of the more absurd stories that rise up out of the deep.
This is a little tricky as Satanism is a broad term these days encompassing a variety of religions. There's "traditional" Satanism which does involve devil-worship and Luciferianism which (sometimes) runs along similar veins. However, there's also "modern" and LaVeyan Satanism which does not, as these Satanists are atheistic, holding the self in the highest position of reverence.
For years I managed the website for the Satanic Continue reading


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The following is an archive of a post made to our
'vox-tech mailing list'
by one of its subscribers.
From: Lance Geroso <email@example.com>Subject: Re: [vox-tech] I'm the guy with the infinite login problemTo: "lugod's technical discussion forum" <firstname.lastname@example.com>Date: Thursday, June 2, 2011, 1:21 AM
Hi, I didn't see the posts you made but... if you run XFCE try this-----> http://www.linuxquestions.org/questions/linuxquestions-org-member-success-stories-23/xubuntu-xfce4-infinite-login-problem-simple-workaround-789843/On Thu, Jun 2, 2011 at 1:09 AM, Bill Broadley <email@example.com> wrote:> On 06/01/2011 03:27 PM, Dr. Denny Scronek wrote:>> 1. Thank you all for your helpoful emails.>>>> 2. I am a pc idiot and I'm too old to change. I use a pc, can't repair a>> pc to save my life.>>>> 3. My pc is a tool and I need it repaired, so>>>>
4. Who wants to make some $$ fixing my beast? How much do you charge?>> When can we get this done? I live close to Sac State.>> Does it have a public IP address? I.e. can I ssh to it? If so I> suspect I or someone else could help you remotely. I'd consider doing> so for free.>> If not there are a few tricks for remote access assuming you have home> internet.>> First thing though, can you hit control-alt-f1, login as yourself or root?>> _______________________________________________> vox-tech mailing list> email@example.com> http://lists.lugod.org/mailman/listinfo/vox-tech>_______________________________________________vox-tech mailing firstname.lastname@example.com://lists.lugod.org/mailman/listinfo/vox-tech
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On a warm spring evening in 2001 in a Northeast Portland bungalow, two dozen strangers–artists, architects, designers, copywriters and philanthropists–were seated around a long table MacGyvered together from two-by-fours and old foam-core doors. Candles flickered; guests chatted about summer plans and delighted in the acquaintances that they, perhaps not so coincidentally, had in common. But their attention mostly centered around a slender, blond-haired, blue-eyed 24-year-old, Michael Hebb, the evening's host, who busied himself by making introductions and pouring more wine, darting in and out of the kitchen, where his girlfriend, Naomi Pomeroy, a pixieish, glitter-eyed 26-year-old, put the finishing touches on the night's dinner: platters of local salmon baked with fleur de sel, caramelized turnips, and artichokes simmered with lemon, herbs and garlic.
Diners passed the food to one another for what seemed like hours. By 10, the party was winding down. While guests ferried dishes to the kitchen, Hebb asked them to throw $5 into the bowl by the door before they left. Despite all appearances, this was a business plan, not a party. It had begun with a home-based catering business for which, according to Pomeroy, shrimp were thawed in the bathtub and dishes were hosed on the lawn. Now it was expanding into clandestine, invitation-only dinners dubbed "Family Supper." This had been the first.
Within a few years Michael and Naomi Hebberoy–the couple famously merged their surnames in 2002–would, with the help of some of Portland's wealthiest citizens, build the upstart venture into what came to be known as the Ripe restaurant empire, a gastronomic supernova so bright it dazzled (some might say blinded) the city. Its gleam reached as far as New York, where the press praised Portland's rise to culinary power; W magazine even dubbed Ripe's creators "the prince and princess of the Pacific Northwest food scene."
Which is perhaps why the city was so astonished last April when Ripe imploded, Michael Hebberoy disappeared, and the Hebberoys' impending divorce received prominent headlines in the Oregonian and other local publications. What the city had perceived to be an entirely new culinary and artistic business model (some used the word "revolution"), complete with its own celebrities, had curdled into disappointment, lawsuits and schadenfreude. Portland, in some ways, had been duped. An illusionist had appeared out of nowhere, made a moderate-sized city with a sizable appetite appear to be a top-tier cultural and culinary metropolis, and then stolen away in the night.
Michael Hebb grew up in Bend and Portland, the son of a father who was 71 when Hebb was born, and who, Hebb claims, "played polo … developed the Salishan Spa & Golf Resort … 'groomed' [Oregon Senator Mark] Hatfield … and was the first person to bring a Jersey cow to the United States," among other things. (Several of Hebb's assertions about his father's past are at best unverifiable; the last is unequivocally untrue.) His father died when Michael was 12 years old. In 1997, after Michael had dabbled in design and architecture at Reed College and Portland State University, he assumed duties as catering manager at Elephant's Deli in Northwest Portland. By night he bused dishes at Zefiro restaurant in Nob Hill, where Michael says he was more interested in making social connections than in cleaning plates.
That same year, Naomi Pomeroy, a petite, dark-haired girl who grew up in Corvallis with a jeweler father and a stay-at-home mother, had graduated from Lewis & Clark but was unsure what to do with her history degree. "I'd lived in India for a year and studied cooking, but I didn't realize it was something I could do as a job," she says, though she landed the occasional catering gig and bused tables at Il Piatto on SE Ankeny St. Then she met Hebb. "He would come into the restaurant, and we both loved dancing so we'd go out to clubs," she says. "He invited me to a potluck dinner at his house, and I pretty much never left."


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Persona 4 Arena walkthrough | Kanji Tatsumi Arcade Mode Ending
He's the bloodcurdling beefcake emperor, with his blooming roses and bulging muscles... it's Kanji Tatsumi. This Persona fighter gets the job done with a never ending supply of folding chairs, yet for some reason seems to think the P-1 Grand Prix is all a dream! Will he figure out what's going on, or will Kanji just pummel his fellow students into submission blissfully unaware?
In this installment, Kanji has taken Labrys's shadow down! Now that he's discovered the mystery behind the P-1 Grand Prix, has he figured out that he wasn't simply dreaming? Will he make friends with this new mechanical student? Let's find out!


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Sometimes, the power of the mainframe is the most cost effective answer. Computing's Peter Gothard puts Computing's readers' questions on the future of the mainframe to IBM's Z13 expert Steven Dickens.
This Dummies white paper will help you better understand business process management (BPM)


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It's around this time of year that many of us will start to think of all those packages that are likely to be delivered containing Christmas presents from our loved ones. In the US alone, it's reckoned that the Postal Service will deliver over 450 million different packages over the holiday season with deliveries being increased to 7 days a week. It makes you wonder how all those packages get sorted quickly and correctly so that we get the right parcel delivered and at the right time. Maybe they trained their workers by using this snappy little 3D puzzle game ... Read more
There are many many games out there that purport to be educational language applications for kids but most are a bit of a let down when it comes right down to it. Some are barely educational and others lack that something special that sparks some interest with the child. Fantasy Tidy Up! is a new kids game for iPad that has a functioning storyline, beautiful graphics and a simple philosophy. It uses text-to-speech technology to teach small kids English vocabulary by having them move objects and put them in their right place in the room. The app 'speaks' in different ... Read more
Flash technology has been around since the mid '90's with simple but quite gorgeous animation technology that pretty well anyone can access. In that time, online, animated flash games have become one of the great little 'time wasters' for we Internet users. Their brightly colored graphics - with the option for interactivity - made them some of the most addictive and fun activities around. There are heaps of sites out there that claim to have the biggest selection of compiled flash games, but mostly they are a disappointment. FlashFreeOnline not only has a huge array of hundreds f thousands of ... Read more
It's not easy to come up with an original game concept these days. YIX is a new game for iOS that actually manages to come up with something a little bit different to keep us amused. Well, to be honest, you can't really call this entertaining and very social game truly original because it's origins lie in games like Cards Against Humanity and Apples To Apples but, with it's use of animated GIFs rather than cards, it offers a unique take on a fun and often hilarious piece of entertainment that you can play with family and friends. The ... Read more
The Tower Defense (TD) style of video game is a sub-genre of real time strategy games where the idea is to try to stop an invading force from making inroads into your territory by using various fighting methods - and anything else you can get your hands on. I guess the genre began when Atari introduces the game Rampart way back in the early 90's. The graphics have changed a lot over the years but the gameplay is basically pretty similar. Hero TD - Ancient Continent is a multiplayer online role-playing game for Android, Blackberry10 and iOS that proves to ... Read more
It must have been my growing up in a household that was stacked with Agatha Christie and Sherlock Holmes novels that led to my love of a genuinely good 'whodunnit' mystery. I used to love trying to figure out who the dastardly murderer was or who stole the jewels from some stately mansion. Then along came the Cluedo board game and it went to another level. The thought of Mr Mustard bludgeoning someone to death with a hammer in the kitchen still haunts me. Things changed inexorably though when fully interactive games like Myst and, later on, Syberia were unleashed ... Read more
According to Goldman-Sachs, Australia is one of the least likely nations to win the twentieth FIFA World Cup when it concludes in the middle of July. I'm sure it didn't take them too long to work that one out. But you can never tell with this Australian team. If i remember rightly, they were within a hairs breath of taking a 10-man Italian team into extra time at the 2006 tournament until a woeful penalty decision gave the Italians victory in the 95th minute. The fact of the matter is, on the big stage, anyone can beat pretty well anybody ... Read more
In case you haven't noticed, the soccer World Cup is due to kick off in just a matter of weeks - assuming the Brazilian venues are all up and running and not crippled by promised local strikes. Whoever you support to win the coveted trophy, there's little doubt that Brazil will be many people's 'second team.' Luis Felipe Scolari's team is a little like the Harlem Globetrotters and are always a pleasure to watch whether you are from Spain, England, Germany or one of the 'minnows' like the USA or Australia. If you are planning to get on the Brazilian ... Read more
With the soccer World Cup due to start in just a few weeks on June 12th, soccer-fever around the world is beginning to hit fever pitch. The USA play their first game against Ghana on June 16th but, given that the team have been drawn into one of many 'groups of death," not even the most ardent fan will give them much of a chance of proceeding through to the second round. Given that the tournament is being played in Brazil, it's hard to see anyone but a South American team picking up the trophy a month or so later. ... Read more
With the Brazil World Cup just around the corner, there's one question all English supporters are asking themselves. Do England have a realistic hope of claiming the trophy? Well, it would be silly to completely rule out a team containing the Liverpool trio of Daniel Sturridge, Raheem Stirling and likely captain Stevie Gerrard not to mention brilliant goalkeeper Joe Hart and Manchester United's Wayne Rooney but it's still very hard to go past a South American country holding up the trophy on July 13th. English supporters are infamous for their vocal support for their team and the England World Cup ... Read more


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GoPro's versatile cameras and accessories enable people to self-capture immersive and engaging footage of themselves enjoying their favorite activities. From extreme to mainstream, GoPro's HERO® line of wearable and gear-mountable capture devices are transforming the way consumers, professional athletes, and video production professionals capture, manage and share meaningful photo and video content. Based in San Mateo, California, GoPro's products are sold through more than 25,000 stores in over 100 countries worldwide and direct via GoPro.com. GoPro branded content is shared and enjoyed by millions of people on popular media channels such as Instagram, Facebook, Twitter, Vimeo and YouTube.
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I think liberals should have a Groundhog Day type of event where they cram a bunch of garbage down a voter's throat (they need something tangible to represent their philosophy) and if the voter doesn't puke until they die they get 4 more years of power.
That said, there is a new Quinnipiac poll out that paints yet another grim picture for the Democrats, where they would lose again in a generic ballot against Republicans.
While this is good news, the thing that irritates me about the reporting of these polls is that they continue to be interpreted, with a acumen of a tax-raising liberal in a recession, as "anti-incumbent sentiment."
This implies there isn't a rational reason to explain why the Democrat's numbers stink worse than poop that fell into a pile of ObamaCare. As if they're not doing anything at all (like
hypothetically speaking defy the will of the public AND OPENLY ADMIT TO IT) to deserve the voter wrath that's marching toward November.
We all know that's ridiculous. This party under Obama's leadership has made so many gaffes you'd think they invented the concept.
I could go ahead and list the examples, but if you don't already know them then this post is probably above your pay-grade anyway....
All of this reminds me of a cartoon I drew many years ago (and is very different from the artwork I do now) that has nothing to do with politics but speaks perfectly to this issue. Basically, the problem Democrats and media have with interpreting the poll numbers goes something like this...
The poll also found that at the moment voters, by a three point margin, would pick ANY REPUBLICAN over Obama in 2012. In other words, every Republican in the country has a viable shot at being president if they were on the ballot against Obama today.
Your dog, if it's registered Republican
and has a verifiable United States birth certificate, could be elected president over Obama .
Even Lindsey Graham could be elected president against Obama! All he'd have to do is become a Republican!
If Quinnipiac's finding is correct I guess even Obama could possibly avoid a scorching 2012 defeat by becoming a Republican, but then again, probably not. I don't think he'd withstand the pressure of the media demanding he show proof of citizenship.


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Plant Protection and Quarantine (PPQ) regulates the importation of plants and plant products under the authority of the Plant Protection Act. PPQ maintains its import program to safeguard U.S. agriculture and natural resources from the risks associated with the entry, establishment, or spread of animal and plant pests and noxious weeds.
Import Requirements for
Accreditation and Certification Programs for Plant Imports
Agriculture Quarantine Inspection (AQI)
Offshore Plant Health Safeguarding Activities


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How they performed ... player-by-player guide to 2011/12 season
Last updated at 17:03, Thursday, 03 May 2012
Danny Hurst: Simply outstanding. Experienced keeper commanded his box, pulled off wonder saves and proved why he is one of the best in non-league. Missed two months of campaign with serious head injury. App: 35. Clean sheets: 7. Mark out of 10: 8.
Shaun Pearson: One of Barrow's most improved players. Has grown in stature and confidence. App: 18. Clean sheets: 4. Mark out of 10: 7.
Gavin Skelton: Solid and reliable at left-back. Vocal on the pitch and a popular member of the squad who brought valuable experience. App: 48. Goals: 0. Mark out of 10: 7.
Paul Smith: Mr versatile. Played right-back and central midfield, doing best in latter role. A fiery character on the pitch, proved to be Barrow's best crosser of a ball. App: 40. Goals: 3. Mark out of 10: 6.
Kelvin Lomax: Failed to hold down a regular place at right-back. Often struggled with his positioning. App: 30. Goals: 0. Mark out of 10: 5.
Phil Bolland: Along with Skelton, the veteran skipper was Barrow's most consistent in an unsettled back-four. Had several different centre-half partners throughout the season. App: 34. Goals: 3. Mark out of 10: 7.
Danny Hone: Arrived on loan from Lincoln in November. A breath of fresh air in the first four months, his form tailed off towards the end of the season. App: 28. Goals: 1. Mark out of 10: 6.
Andy Nicholas: Warmed the bench for the most part and often left out in favour of loan arrivals. Failed to really impress when given a chance. App: 23. Goals: 0. Mark out of 10: 5.
Mike Pearson: Barrow's best defender until season was cruelly cut short due to broken leg and ankle suffered in FA Cup defeat against Rotherham. App: 11. Goals: 1. Mark out of 10: 6.
Cliff Moyo: A teenager with raw talent, showed he has potential but still a lot to learn. Had loan spells at Northwich and Droylsden. App: 9. Goals: 0. Mark out of 10: 6.
James Owen: Took over the midfield terrier role vacated by Robin Hulbert. Ran and tackled his heart out for the Bluebirds' cause. App: 38. Goals: 0. Mark out of 10: 8.
Richie Baker: Hit a Baker's dozen of 12 goals, six of which came from the penalty spot. Most effective when team played well. App: 44. Goals: 12. Mark out of 10: 7.
Andy Ferrell: Huge disappointment. Was expected to be the midfield leader but failed to deliver the goods. App: 19. Goals: 0. Mark out of 10: 4.
Robin Hulbert: Season wrecked by knee injury suffered in the first month. Helped manager Dave Bayliss on the sidelines. App: 8. Goals: 0. Mark out of 10: 5.
Paul Rutherford: Troubled by thigh problem, the nippy winger blew hot and cold. Right footed but played most of campaign on left flank. Now only six appearances short of 150 for the club. App: 46. Goals: 2. Mark out of 10: 7.
Jack Mackreth: A revelation on the right wing. Electric pace terrorised defenders, enabling him to set up countless goals – especially in the early months – for strikers. Made more appearances than any other Barrow player, despite struggling with foot problem. App: 49. Goals: 5. Mark out of 10: 9.
Adam Boyes: Started season on fire with 16 goals in first 19 games, including four in one FA Cup tie against Witton Albion. Struggled with confidence in months that followed, bagging six more in a further 27 appearances. Played for England C. App: 46. Goals: 22. Mark out of 10: 8.
Andy Cook: Powerhouse frontman came of age in 2011/12. Barrow's top scorer in league with 17 goals, he bullied defenders and got his reward. Hat-trick against Fleetwood will live long in the memory. App: 43. Goals: 18. Mark out of 10: 8.
Joe Jackson: Local striker made instant impact during loan spell from Burnley. Showed he has the talent to go far in game. App: 7. Goals: 3. Mark out of 10: 7.
Adam Quinn: Big centre-half won lots of headers but struggled for pace. App: 18. Goals: 0. Mark out of 10: 6.
Louis Almond: Attacker fell a long way short of standard shown in previous loan spell at Barrow. App: 28. Goals: 1. Mark out of 10: 4.
Alex-Ray Harvey: Worked hard in midfield and never shirked a tackle. App: 14. Goals: 1. Mark out of 10: 6.
Dominic Rowe: Diminutive winger showed plenty of potential. App: 8. Goals: 1. Mark out of 10: 6.
Paul Edwards: App: 4. Goals: 0. Darren Sheridan: App: 2. Goals: 0. Ryan Brooke: App: 5. Goals: 0. Haydn Hollis: App: 3. Goals: 1. Chris Turner: App: 5. Goals: 0. Stuart Dixon: App: 1. Goals: 0. Jack Cudworth: App: 1. Goals: 0. Mike Rushton: App: 1. Goals: 0. Ben Beresford: App: 1. Goals: 1. Michael Ricketts: App: 1. Goals: 0. Salou: App: 1. Goals: 0.
* Appearances and goals are in all competitions (Blue Square Bet Premier, FA Cup, FA Trophy and Lancs Trophy).
First published at 13:25, Wednesday, 02 May 2012
Published by http://www.nwemail.co.uk
Have your say
I think the ratings are fair, And also am glad Bayliss has got rid of Nicholas, lomax and a couple more players. Nicholas was a under average defender and i knew he wouldnt get a contract, lomax, half decent footballer, but he needs to start all over again, get plenty of games and reach his full potential. Barrow have some good players now, i hope they sign Danny Hone as he is a free agent, id also be looking at another Lincoln player or two, If barrow can get a sterdy defence next season then i think we will have a great football package and then on see what the 2012/2013 season will bring.
Danny Hurst deserves at least a 9, if it wasn't for him we'd be looking at relegation again. How he's still playing non-league is a complete mystery to me.
View all 3 comments on this article


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The 28" Hexagon Starburst Portable Heavy Duty Fire Pit Ring makes it possible to bring the open fire with you wherever you go. Built with heavy-duty durability and equipped with a zipper tote bag, this fire pit ring is designed to easily be carried along for the ride.
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Out of the bag and assembled in a matter of seconds, the 28" Hexagon Starburst Portable Heavy Duty Fire Pit Ring is designed for a night on the move. The heavy-duty I-beams can withstand frequent set-up and tear-down, and the included zipper tote will keep things portable. This fire pit ring is covered under a five year warranty, ensuring a little extra peace of mind.


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Brett Crosby is the Group Product Marketing Manager of Google Analytics. He has been shaping the Web Analytics industry for ten years as the co-founder of Urchin Software Corporation and more recently as a senior product
leader at Google. He is currently responsible for product positioning, feature roadmap development and all external product communications. Brett holds a degree from USC in Political Science and International Relations.
Mir Imran founded InCube Laboratories in 1995 to focus on his passion: creating medical device solutions that change the standard of care in critical healthcare markets. Mir began his career as a med-tech entrepreneur in
the late 1970's. Over the decades, he has become one of the world's most successful inventors, entrepreneurs and investors in healthcare. Mir now holds more than 200 issued patents - and is perhaps most well known for his pioneering
contributions to the first FDA-approved Automatic Implantable Cardioverter Defibrillator. Mir's current crop of inventions includes advanced treatments for neural aneurysms, epilepsy, ulcerative colitis, obesity and chronic pain, among
others. Most of these will enter clinical trials in the 2008 to 2010 timeframe. As an entrepreneur, Mir has founded over 20 medical device companies, including: Vidamed (acquired by Medtronic), Physiometrix, Cardiac Pathways, Advanced
Cytomextrix (acquired by Oncotech 1997), Percusurge (acquired by Medtronic 2001), Reflow, Inc. (acquired 1999), Safeview (acquired by L3 2006) Intrapace (founded 2001), Spinal Modulation (founded 2005) and Zonare (founded 1999). As an
investor, Mir serves as the Life Science Venture Partner for DFJ ePlanet, where he has led 9 investments in a range of promising ventures around the globe. Mir is also an active angel investor, with a portfolio based around both medical
and pharmaceutical ventures. Mir currently holds board seats with Bodymedia, Cardiovasc, Intrapace, Egeen International, Spinal Modulation, ZARS and Zonare. Mir holds an MS in Bio-Engineering and a BS in Electrical Engineering from
Rutgers, where he spent three years as a Research Specialist.
Prior to joining B Lab, Kassoy spent 16 years in the private equity business, most recently as a partner at MSD Real Estate Capital, an affiliate of MSD Capital, the $12 billion investment vehicle for Michael Dell.
Kassoy is dedicated to growing innovative for-profit and non-profit models for social change. He is a board member of Working Today and the Freelancers Union, which provide affordable health insurance and other financial services to
independent workers in thirty-two states. He also sits on the boards of Echoing Green, Wall St. Without Walls, and acts as an advisor to Civic Builders. Andrew was raised in Boulder, Colorado and graduated with distinction from Stanford
University, where he was a Truman Scholar and President's Award winner. In 2001, he was named a Henry Crown Fellow by the Aspen Institute. Kassoy has also been active in Colorado politics, and he has served as a member of the Council on
Foreign Relations. He is married to Kamy Wicoff, a writer, and he has two young sons.
Ken Wilcox is president and CEO of SVB Financial Group. Since January 2000, when he took on the role, Wilcox has successfully pursued a strategy of expansion and diversification, while remaining focused on the company's
core niches of technology, life sciences, private equity and premium wineries. Wilcox joined Silicon Valley Bank in 1990 when he co-founded the company's East Coast Technology Division. In this role, Wilcox managed the first regional
office of Silicon Valley Bank and was responsible for all lending activity east of the Mississippi River. Upon promotion to chief banking officer in 1997, Wilcox moved from Massachusetts to California and became president and CEO within
four years. Prior to joining Silicon Valley Bank, Wilcox spent two years as a member of the Technology Lending Group with the Bank of New England and five years at Shawmut Bank in Boston. Prior to his banking career, Wilcox was a professor
of German at The University of North Carolina at Chapel Hill. Wilcox received a bachelor's degree in German studies from Oakland University and a Ph.D. in German Studies from The Ohio State University. He also earned a master's of business
administration from Harvard Business School. Wilcox is a member of the board of directors of the Federal Reserve Bank of San Francisco and the Silicon Valley Leadership Group.
Jeffrey Housenbold is President & CEO of Shutterfly, Inc., an internet-based social expression and personal publishing service. Shutterfly provides a full range of products and services that enable consumers to
manage their digital photographs. Housenbold has a successful track record of building online consumer franchises by combining commerce and community. In June 2006, he received the Ernst & Young Entrepreneur of the Year Award in the
Retail and Consumer Products category for the Northern California region. Previously, Housenbold was Vice President of Business Development & Internet Marketing at eBay, where he managed customer acquisition and retention. At eBay he
also held positions as Vice President & General Manager of its Business-to-Consumer Group and Vice President of Mergers and Acquisitions. Formerly, he held senior management positions with AltaVista, including Vice President &
General Manager, and was the Chief Operating Officer of Raging Bull, the community finance portal. He also served as Vice President of Corporate Development at WinStar Communications and as Manager and Founder of Accenture's Media &
Entertainment Strategy Group. Housenbold completed his undergraduate degree with High Honors at Carnegie Mellon University in Economics and Business Administration and was also a Presidential Scholar. He went on to earn his MBA from
Harvard Business School where he was a Dean's Fellow. Housenbold is the co-author of The Shutterfly Guide to Great Digital Photos, an instructional book published by McGraw-Hill on the essentials of digital photography and managing images.
He is an avid photographer with his Canon 30D.
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text:
Dr Oz did a show with Deepak Chopra, an Alternative Health All-Star, who taught us How To Meditate to Lose Weight and the Secrets to Reverse Aging. Doctor Oz said that Deepak Chopra's approach combines the body, mind, and spirit and that he is considered one of the rock stars of alternative treatment. In March […]
Posts Tagged ' Deepak Chopra How To Tell If You Are Hungry '
Dr Oz & Deepak Chopra: Meditate To Lose Weight: 5 Minute Meditation
By Dr Oz Fans on January 5, 2011