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I'm redoing my seat upholstery and need to replace the diaphragm, actually I think this is a weak point in the seat. Has anyone replaced it with wood or metal? or even jute webbing?
I think the foam and additional foam cushion that I'm using is more than sufficient to make it comfortable. Any ideas on this subject???. Thanks.John G.

subset: commoncrawl


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Windows 8 UEFI with Secure Boot
No Free Boots
The coming Windows 8 implementation of UEFI with Secure Boot adds an extra layer of complexity for some Linux users. We look at the problem and two solutions from Fedora and Canonical.
In an effort to provide additional security to Windows 8 on x86- and ARMbased devices, a new requirement for Microsoft ODMs is that all Windows 8-certified machines have the Unified Extensible Firmware Interface (UEFI) with the Secure Boot option on, creating problems for any Linux distribution that wants to run on such devices.
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Code.org and College Board Team Reach Out for Talented High School Coders
New partnership will bring more and better CS training to US schools
A Peek Inside TeslaCrypt Ransomware
Criminals offer online help over Tor network
Mumblehard Still Spams
Sophisticated malware is still present on Joomla and WordPress sites around the world.
Launchpad Gets Git
Future versions of Ubuntu's code service will support the popular Git version control system used with Linux and other open source projects.
AMD Posts Code for Linux GPU Driver
New release marks the arrival of AMD's unified driver strategy.
30 Percent of New Server Equipment Goes to Cloud Infrastructure
A new study by IDC charts big changes in the big hardware market.
Windows Might Go Open Source
Azure CTO says Redmond has already considered the unthinkable.
Linux Mint Will Stay with Ubuntu
Lead developer quells rumors that the Debian version is slated for center stage.
Microsoft Frees Code for .NET Build Engine
MSBuild is now just another GitHub project as Redmond continues its path to the light.
Researchers Demonstrate Hack by Heat
Malware could pass data and commands between disconnected computers without leaving a trace on the network.


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Join our energetic and passionate team at the National Archives Foundation.
As the independent nonprofit that serves as the National Archives' private-sector partner in the support of exhibitions, educational initiatives and public programs, your work with the Foundation will contribute to our mission to educate, enrich, and inspire a deeper appreciation of our country's heritage through the records held in trust by the National Archives.
The Foundation offers opportunities for employment and internships with a competitive benefits package. Job postings are updated regularly. We welcome applications and inquiries.
We have no open positions at this time.
Interested in an internship? We are always looking for candidates for communications, development, and special events interns. Send your resume and a cover letter to email@example.com to be considered on a rolling basis.


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Canon of Sherlock Holmes
5,000 - 10,000 downloadsAdd this app to your listsTweets por @Appszoom
The four novels are:
1) A Study in Scarlet
2) The Sign of the Four
3) The Hound of the Baskervilles
4) The Valley of Fear
The fifty-six short stories are collected in the following five books:
1) The Adventures of Sherlock Holmes
2) The Memoirs of Sherlock Holmes
3) The Return of Sherlock Holmes
4) His Last Bow
5) The Case-Book of Sherlock Holmes
Tags: 4 novels of sherlock holmes, sherlock close sign, themes in sherlock holmes canon.
(27 stars)
Elementary my dear Watson.
(27 stars)
Thank you for putting them all in one app. It's so hard to find some of the stories now.. Some are even sold in such high prices (in which it shouldn't be because the copyright has already expired). Thanks!!!
(27 stars)
Great reading for my wife who is a sherlock fan since high school.
(27 stars)
(27 stars)
Sherlock Holmes is one of my favorite fictional characters ever, and right under Shakespeare, Sir Arthur Conan Doyle is my favorite writer. Awesome app!!!!
(27 stars)
I've actually been liking the app until I updated it today to find its only daylight background.While all other new features are heartfully welcomed but I personally liked the earlier version's dark backlight and so was hugely disappointed by this development. I strongly urge to either fix it back or to provide both options. Please!
(27 stars)
Every time my phone turns off pr the app fails, I lose my place! It's irritating and simply unnecessary!


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Last-Minute Spring Break Trips, Away From the Party Set
In need of a quick, sunny getaway? Some destinations where you can escape the winter — and hard-partying college students.
In need of a quick, sunny getaway? Some destinations where you can escape the winter — and hard-partying college students.
By STEPHANIE ROSENBLOOM
By AMY HARMON
Seeking a more untamed wildlife experience, a family heads to the remote Osa Peninsula on the country's Pacific coast.
By ELAINE GLUSAC
Go hotel hopping on this five-country tour of notable new properties in the region.
By DAVE SEMINARA
The debate over paving a road in Santa Teresa speaks to larger tensions between development, preservation and health.
By BONNIE TSUI
On a peninsula in northwest Costa Rica, aspiring wave riders go to surf school alongside an exotic jungle habitat.
By JOE STANGE
In a country not known for its food, a small but growing number of restaurateurs and chefs are applying creativity and skill to homegrown flavors.
By GISELA WILLIAMS
Manuel Pinto found his property in Costa Rica while hacking through the jungle.
By GISELA WILLIAMS
The laid-back, untamed vibe of Costa Rica's Caribbean coast attracts surfing disciples and soul-searching world travelers.
By ETHAN TODRAS-WHITEHILL
This Central American country is a destination of multiple personalities: challenging adventure spot, pioneering eco-retreat and luxurious getaway.
By NICK KAYE
A mountaintop golf community in North Carolina, and a residential resort with an extensive marina in Costa Rica.
By NICK KAYE
A residential community aimed at outdoors enthusiasts in Garden Valley, Idaho, and a beachfront residential resort in Jacó, Costa Rica.


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- Exchange: Saudi Arabia
- Sector: Financials
- Industry: Real Estate
- Sub-Industry: Real Estate Owners & Developers
Knowledge Economic City Co+ Add to Watchlist
As of 09:30:15 ET on 06/02/2015.
Company Profile for Knowledge Economic City Co (KEC)
Knowledge Economic City Co is an economic city being developed in Al-Madinah, Saudi Arabia. The City will focus on intellectual property, knowledge-based industries, medical, hospitality, tourism and multi-media.
Contact Information
Knowledge Economic City Co
Tower B 5 Salama Center
Prince Sultan St P O Box 6360
Jeddah, 21442
Saudi Arabia
Phone: 966-2-616-5577
Fax: 966-2-616-5588
Key Executives for Knowledge Economic City Co (KEC)
|Bandar Bin Salman Bin Mohammed Al SaudChairman
|Abdul Rauf Bin Mohammed Abdullah MannaVice Chairman
|Taher Mohammed BawazirManaging Director
Quotes delayed, except where indicated otherwise. All prices in local currency. Time is ET.
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HOUSTON Police are searching for leads after a male teenager was found shot in the head late Saturday in his southwest Houston apartment.
According the Houston Police Department, officers responded to a call of a shooting around midnight at the Houston Westlake Apartments located on Kings Circle. When police arrived at the scene, they found an 18-year-old male with multiple gunshot wounds including one to the head.
The victim was transported to a local hospital in an unknown condition, police said.
Investigators said the victim had been shot in his apartment and was found by his family. The family had heard the gunshots from upstairs and came down to find the victim.
HPD is asking anyone with information about the shooting to call Houston Crime Stoppers.


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Hayden Panettiere and Carrie Underwood Wear Dark Eye Makeup and Light Lip Colors
Which blonde beauty's CMAs look do you like better?
Hayden might not be a country singer, but she plays one on TV! The actress looked picture perfect with her classic white dress, chic updo, and neutral lip gloss. To kick her makeup up a few notches, she added smoky shadow, jet black eyeliner, and ultra-long lashes to finish off the look.
Carrie wore a white dress embellished with gold accents and her hair curled and brushed into a low ponytail that swept over her shoulder. Like Hayden, her clear complexion and glossy nude lips play second fiddle to her dark, bold eye makeup.
Both stars look gorgeous at the CMAs, but whose look wins your vote?


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Health News Archive - February 04, 2009
A person's heritage may initially dictate aging -- but stresses such as divorce or weight gain/loss can add years to your visage, U.S. researchers say. Dr.
CONTINUA WINTER SUMMIT and TOKYO, February 4 /PRNewswire/ -- Bluegiga announced today that its OEM Bluetooth modules are now available with Bluetooth Health Device Profile (HDP).
HUNTINGTON BEACH, California and AMSTERDAM, February 4 /PRNewswire/ -- Agendia, a world leader in molecular cancer diagnostics, today announced that its signature breast cancer test MammaPrint(R) will be offered as standard of care for all eligible early stage breast cancer patients at the Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NKI-AVL).
Unique idea for his-and-hers Valentine's Day gifts that truly demonstrate couple's love ATLANTA, Feb. 4 /PRNewswire/ -- While Valentine's Day is the perfect opportunity for couples to express their love for one another, there are so many trite gifts often used to convey this important message.
WASHINGTON, Feb.
Marshall Edwards Accelerates Study Timeline and Experiences Cost Reduction through Perceptive Alliance with AG Mednet BOSTON, Feb.
BOTHELL, WA, and VANCOUVER, Feb. 4 /PRNewswire-FirstCall/ - OncoGenex Pharmaceuticals, Inc.
BOTHELL, Wash., Feb.
BELGIUM, Wis., Feb.
DETROIT, Feb. 4 /PRNewswire-USNewswire/ -- The Wayne County Medical Society Foundation will hold its annual Chinese New Year Fundraiser to benefit the foundation's Elder Abuse Prevention Program on Sunday, Feb. 15, at the Golden Harvest Restaurant at 6880 E. 12 Mile Road in Warren.
- An uxorious, effeminate, or spiritless man.
- A timorous, cowardly fellow.


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South Carolina and Georgia have turned down Medicaid expansion despite having many working families who lack health insurance. Georgia can't afford the expansion and the federal government might not have the capacity to provide continuous funding in the future, Gov. Nathan Deal said.
View Full Article in:Augusta Chronicle (Ga.), The


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German labor chief in Manila for inking of deal for Filipino health care workers
MANILA, Philippines – The German Labor and Social Affairs Minister, Dr. Ursula von der Leyen, came to the Philippines Monday to witness the signing of an agreement allowing Filipino health care professionals to work in Germany.
"The German Minister is in Manila for an official visit to witness the signing of the Agreement Concerning the Placement of Filipino Health Care Professionals in Employment Positions in the Federal Republic of Germany," the Department of Foreign Affairs (DFA) said in a statement.
"The Agreement is expected to open the German health care sector to Filipino health care professionals who have been, heretofore, barred from employment in accordance with existing German laws," it said.
Leyen had also paid a courtesy call to Foreign Affairs Secretary Albert del Rosario Monday morning aside from witnessing the signing of the agreement at the Department of Labor and Employment.
"The initiative to help facilitate the deployment of Philippine health care professionals, nurses in particular, to Germany has been high in the agenda of the two countries," DFA said.
"It was taken up during the official visit of Secretary del Rosario to Germany in December 2011 and during the visit to Manila of German Federal Foreign Minister Dr. Guido Westerwelle [February this year]," it said.
The agreement was described by Del Rosario in the statement as a "win-win situation for both countries."
"On the one hand, the Philippines will be able to help Germany fill its needs for health care professionals," DFA said.
"On the other, Philippine health care professionals will be given the opportunity to be employed in Germany, a country which is known for its excellent labor and social welfare standards," it added.
According to 2010 statistics of the Philippine Overseas Employment Agency (POEA), an estimated 21,724 to 29,273 nurses and caregivers leave the Philippines annually for greener pastures abroad.
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The major issues before our nation, and of the world run deeper, more profound, than political labels and simplistic arguments currently maintain. We have framed our debate in almost Homer Simpsonesque style, fittingly delivered through endless sound bites, and cursory analysis on traditional news outlets. Korten maintains that we rely heavily upon the most effective (and cynical) educational tool ever devised: mass media advertising.
Monterey Bay Aquarium—Cooking For Solutions Sustainable Foods Institute: David Mas Masumoto
This post is under construction. A new video player will be added shortly. Inspiring writer, and passionate sustainable farmer, David Mas Masumoto, shares his views on farming, on life, and the inherent tensions that arise, the "creative edge," from the art of writing, and of being a farmer. Filmed in May 2010 at the Monterey […]
Paul Hawken: The High Cost of Cheap Food (video)
Paul Hawken eloquently explains how the price of food is divorced from its true costs, and what this really means for society.
Cooking For Solutions Sustainable Foods Institute: Excerpts of Sample Talks 2010
This post is under construction. A new video player will be added shortly. The Monterey Bay Aquarium Cooking For Solutions Sustainable Foods Institute annual conference, a two day event for the media to promote learning and discussion around the many issues that impact food and sustainability issues. This year's talks and panel discussions brought together […]
Carlo Petrini: Good, Clean, and Fair part 6 (video)
Slow Food founder Carlo Petrini argues for economic respect, and fairness to the small farmers of the world. Economy and ecology share the same roots, both require a local context in order to survive.


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STARmeterSEE RANK
Down 11,576 this week
Dan Rosen (I)
Dan Rosen wrote, co-produced, and appeared (as Deputy Hartford) in The Last Supper (1996), a black comedy whose pointed critique of faux-liberalism is not pursued with sufficient vigor. His directorial debut, The Curve (1998) aka Dead Man's Curve, was shot in his native Maryland, and was far more effective in pursuing its dark vision of the human ... See full bio »
Born:in Baltimore, Maryland, USA
More at IMDbPro » Contact Info: View agent
Represent Dan Rosen? Add or change photos


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Wells Fargo Archive
Banks and Credit Unions Must Improve Cross-Sell Efforts
Cross-selling in banking requires the use of customer analytics to build appropriate offers and deliver effective communication.
Wells Fargo Uses $$ and Pop-Up Branches to Introduce Apple Pay
The use of pop-up branches and social media by Wells Fargo provided a low-cost way to introduce and promote their Apple Pay partnership.
Big Banks Promote Apple Pay Partnership
Before Apple Pay even been launched publicly, Apple's banking partners started heavily promoting their relationship in digital media.
8 Steps to Improved Bank and Credit Union Cross-Selling
Cross-selling is the best way to achieve growth in banks and credit unions. Here are 8 surefire ways to improve cross-selling results.
Angry Big Bank Customers Could Put $230 Billion In Play
The ten largest retail bank brands in the U.S. stand to lose a combined $92 billion in deposits next year. Smells like opportunity for everyone else.
Wells Fargo Revamps Website Homepage With Lifestage Carousel
The bank's new design replaces a messy "link farm" with a snazzy interactive ribbon structured around life needs, but reviews of the site are mixed.
Gen-Y Stressed Most Over Debt, Making Savings a Distant Dream
Debt causes millennials the most financial pain, paralyzing their ability to save for retirement. They need help, but prefer talking to grown-ups with experience.
BMO Tests Nanobranch Strategy With Studio-Sized Store
BMO's 'studio branch' measures less than 900 square feet. As banks build smaller and smaller branches, one question remains: How tiny can these nanobranches get?
Wells Fargo Mini-Branches And The Shrinking Retail Footprint
Wells Fargo's new branch concept -- what it calls "the neighborhood bank format" -- has a footprint one-third of the size of a typical location. Take a look.
Significant Others: Targeting Gays And Lesbians In The Banking Sector
As societal attitudes towards the LGBT community have evolved, so too have financial marketers' approach to this lucrative target market. What are banks doing and why?
Banks Make Customer Experience Gains, But Credit Unions Are Crushing It
The banking industry has steadily improved their customer service and satisfaction scores over the last three years, but credit unions are way in the lead.
Wells Fargo ATMs Can Predict What People Want
Using predictive analytics, Wells Fargo's new ATMs present customers with an array of buttons all based on their previous transactions and preferences.
Banks Fearing Scrooge Image Halt Evictions For Christmas
Most large banks have announced -- and rather publicly -- that they are halting foreclosure evictions for the holiday season. A gesture of good will? Or an awkward PR play?
Chase Tops Big Banks In Harris/Google Customer Satisfaction Study
59% of Chase customers say they are "satisfied" or "extremely satisfied," compared to Citi at 55%, BofA at 48% and Wells Fargo at 47%.
'Bundling' Key To Cross-Selling Banking Products
Author Tom O'Rourke shares his experience creating "checking bundles" for Wells Fargo, explaining the four-step process behind their success.


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White supremacist executed for Texas dragging
HUNTSVILLE, Texas White supremacist gang member Lawrence Russell Brewer was executed Wednesday evening for the infamous dragging death slaying of James Byrd Jr., a black man from East Texas.
Byrd, 49, was chained to the back of a pickup truck and pulled whip-like to his death along a bumpy asphalt road in one of the most grisly hate crime murders in recent Texas history.
Brewer, 44, was asked if he had any final words, to which he replied: "No. I have no final statement."
He glanced at his parents watching through a nearby window, took several deep breaths and closed his eyes. A single tear hung on the edge of his right eye as he was pronounced dead at 6:21 p.m., 10 minutes after the lethal drugs began flowing into his arms, both covered with intricate black tattoos.
Byrd's sisters also were among the witnesses in an adjacent room.
"Hopefully, today's execution of Brewer can remind all of us that racial hatred and prejudice leads to terrible consequence for the victim, the victim's family, for the perpetrator and for the perpetrator's family," Clara Taylor, one of Byrd's sisters, said.
She called the punishment "a step in the right direction."
"We're making progress," Taylor said. "I know he was guilty so I have no qualms about the death penalty."
Appeals to the courts for Brewer were exhausted and no last-day attempts to save his life were filed.
Besides Brewer, John William King, now 36, also was convicted of capital murder and sent to death row for Byrd's death, which shocked the nation for its brutality. King's conviction and death sentence remain under appeal. A third man, Shawn Berry, 36, received a life prison term.
"One down and one to go," Billy Rowles, the retired Jasper County sheriff who first investigated the horrific scene, said. "That's kind of cruel but that's reality."
It was about 2:30 a.m. on a Sunday, June 7, 1998, when witnesses saw Byrd walking on a road not far from his home in Jasper, a town of more than 7,000 about 125 miles northeast of Houston. Many folks knew he lived off disability checks, couldn't afford his own car and walked where he needed to go. Another witness then saw him riding in the bed of a dark pickup.
Six hours later and some 10 miles away on Huff Creek Road, the bloody mess found after daybreak was thought at first to be animal road kill. Rowles, a former Texas state trooper who had taken office as sheriff the previous year, believed it was a hit-and-run fatality but evidence didn't match up with someone caught beneath a vehicle. Body parts were scattered and the blood trail began with footprints at what appeared to be the scene of a scuffle.
"I didn't go down that road too far before I knew this was going to be a bad deal," he said at Brewer's trial.
Fingerprints taken from the headless torso identified the victim as Byrd.


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Amish attacks resentencing scheduled for March
Police: Kidnappers wanted to make 2 Amish girls their 'slaves'
Police: Couple used 'coercion tactics' to kidnap Amish girls, may have plotted to kidnap more kids
Missing Amish girls found safe and alive in upstate NY after apparent abduction
Pennsylvania crash kills two in horse-drawn Amish buggy
Authorities say a vehicle crashed into a horse-drawn Amish buggy in western Pennsylvania, killing two people in the buggy and seriously injuring a third.
Beware the Mullets: Radical Amish arrested for hair-cutting attacksComment
Seven members of the fundamentalist Amish group were arrested, including Sam Mullet and his three sons, and charged with attacking and forcibly cutting the beards and hair of Amish men and women and then taking photos of them.
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Rita Ora - How We Do (Party)
Artist: Rita Ora
Producer: The Runners
Album: ORA
Avg Rating: 2.1 ( 11 votes )
Unable to Watch this Youtube Video? Click here to play in Soundcloud instead.
Though Juicy will be a hip-hop touchstone for as long as there are rap hopefuls to quote its opening couplet, Party and Bullsh*t seems to have momentarily overtaken it as the Biggie reference du jour; the '93 single recently inspired records by August Alsina (Party & Bullsh*t), Andrew Lewis (Party & Bullsh*t) and even 50 Cent (Bullsh*t and Party). The latest artist to put their spin on the partying/bullsh*tting theme, Rita Ora returns to our pages with Roc Nation debut single How We Do (Party) (Originally titled… wait for it… Party & Bullsh*t). Premiered Tuesday by Ora and label boss Jay-Z on NY Top 40 station Z100, the record finds beat crew The Runners juxtaposing a pop-rock guitar with bass-booming reverb-drenched percussion as the singer/songwriter encourages listeners to let go of their cares and paint the town red. An eminently catchy ode to revelry and young love, this pop-appealing selection seems poised to take over airwaves and club dancefloors in the weeks ahead—or do I have it twisted? If you agree with my assessment, then keep it locked for more fresh tunes from Ora, as well as the latest on her as yet untitled/unscheduled Roc Nation debut.
Written by richard on Apr 17, 2012
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Far From the Glow in China, There Are No Games in Darfur
By DeWayne Wickham
What China wants during these Olympics it cannot be allowed to have. More than anything else, the emerging superpower wants to bask in the glory of its role as host of the quadrennial global sports festival. It wants the worldwide embrace that traditionally has come to nations bestowed this honor.
Of course, such acceptance hasn't always been merited. Nazi Germany hosted the Olympics in August 1936, just 11 months after it stripped German Jews of their citizenship and banned them from marrying blond, blue-eyed Germans. And the Soviet Union invaded Afghanistan seven months before Moscow hosted the Olympics in July 1980.
The U.S., which took part in the 1936 Olympics but boycotted the 1980 contest, is represented in China by 596 athletes and George W. Bush, the first U.S. president to attend an Olympic opening ceremony abroad. Bush said it "would be an affront to the Chinese people" if he didn't attend.
He ought to be more concerned about the people of Darfur, the embattled region of Sudan where it's estimated that 300,000 people have been killed and 2.7 million displaced by fighting that has raged in the African country since 2003.
Three years ago, Bush called the attacks by government-backed militias on ethnic minorities in Darfur a "genocide." In July, the International Criminal Court indicted Sudanese President Omar al-Bashir on genocide charges and is considering issuing a warrant for his arrest. China is Sudan's biggest arms supplier. If the Sudanese leader were proven to have committed genocide, China — which gives Sudan the means to carry out this carnage — would be guilty of complicity.
China's sins
China's unbroken link to the genocide in Darfur should make a lot of people cringe at the legitimacy the Games now taking place in Beijing give the world's largest communist nation. But these days, the centuries-old tradition of the Olympic Truce, where warring factions would suspend fighting during the Games, has been replaced with one of indifference. As the rape and slaughter of people in Darfur go on, the U.S. Olympic team picked a refugee from Sudan — who is now a U.S. citizen — to carry this country's flag during the opening ceremony last week.
China had to be relieved that it got off so easily.
The worldview
The world has shown much greater tolerance for genocide in Africa than in Europe. About 800,000 people were killed in Rwanda during a span of a little more than three months in 1994 as the international community did virtually nothing. A token force of peacekeepers from African nations has been dispatched to Darfur but has been unable to stop the bloodshed.
When the former Yugoslavia fractured into warring parts, the response was different. Thousands of U.S. and NATO troops were sent into two breakaway regions — Kosovo and Bosnia — to stop ethnic cleansing. They stayed for years to keep the war's smoldering ashes from reigniting.
Without significant pressure from other nations, China has done little to pressure the Sudanese government to end the attacks on the people of Darfur. A serious boycott threat might have gotten China to act in the months leading up to the Olympics, but that didn't happen.
Now that the Games are under way, it is up to the athletes who have descended upon Beijing to find a way to signal their disapproval of China's support of the mass killings in Sudan. Some of them have already rejected such a role by saying that they are athletes, not politicians.
They should be reminded that those who commit genocide recognize no such distinction.
DeWayne Wickham writes on Tuesdays for USA TODAY. (c) Copyright 2008 USA TODAY, a division of Gannett Co. Inc. <>>


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Relationships between kinetic constants and the amino acid composition of enzymes from the yeast Saccharomyces cerevisiae glycolysis pathway
- Peteris Zikmanis,
- Inara Kampenusa
- … show all 2 hide
The kinetic models of metabolic pathways represent a system of biochemical reactions in terms of metabolic fluxes and enzyme kinetics. Therefore, the apparent differences of metabolic fluxes might reflect distinctive kinetic characteristics, as well as sequence-dependent properties of the employed enzymes. This study aims to examine possible linkages between kinetic constants and the amino acid (AA) composition (AAC) for enzymes from the yeast Saccharomyces cerevisiae glycolytic pathway. The values of Michaelis-Menten constant (KM), turnover number (kcat), and specificity constant (ksp = kcat/KM) were taken from BRENDA (15, 17, and 16 values, respectively) and protein sequences of nine enzymes (HXK, GADH, PGK, PGM, ENO, PK, PDC, TIM, and PYC) from UniProtKB. The AAC and sequence properties were computed by ExPASy/ProtParam tool and data processed by conventional methods of multivariate statistics. Multiple linear regressions were found between the log-values of kcat (3 models, 85.74% < Radj.2 <94.11%, p < 0.00001), KM (1 model, Radj.2 = 96.70%, p < 0.00001), ksp (3 models, 96.15% < Radj.2 < 96.50%, p < 0.00001), and the sets of AA frequencies (four to six for each model) selected from enzyme sequences while assessing the potential multicollinearity between variables. It was also found that the selection of independent variables in multiple regression models may reflect certain advantages for definite AA physicochemical and structural propensities, which could affect the properties of sequences. The results support the view on the actual interdependence of catalytic, binding, and structural residues to ensure the efficiency of biocatalysts, since the kinetic constants of the yeast enzymes appear as closely related to the overall AAC of sequences.
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- Gerosa, L, Sauer, U (2011) Regulation and control of metabolic fluxes in microbes. Curr. Opin. Biotechnol 22: pp. 1-10 CrossRef
- Agarwal, PK (2006) Enzymes: an integrated view of structure, dynamics and function. Microbial Cell. Fact 5: pp. 2 CrossRef
- Kraut, DA, Carroll, KS, Herschlag, D (2003) Challenges in enzyme mechanism and energetics. Annu. Rev. Biochem 72: pp. 517-571 CrossRef
- Pegg, SC, Brown, SD, Ojha, S, Seffernick, J, Meng, EC, Morris, JH, Chang, PJ, Huang, CC, Ferrin, TE, Babbitt, PC (2006) Leveraging enzyme structure-function relationships for functional inference and experimental design: the structure-function linkage database. Biochemistry 45: pp. 2545-2555 CrossRef
- Nevoigt, E (2008) Progress in metabolic engineering of Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev 72: pp. 379-412 CrossRef
- Magyar, C, Tudos, E, Simon, I (2004) Functionally and structurally relevant residues of enzymes: are they segregated or overlapping?. FEBS Lett 567: pp. 239-242 CrossRef
- Boehr, DD, Nussinov, R, Wright, PE (2009) The role of dynamic conformational ensembles in biomolecular recognition. Nat. Chem. Biol 5: pp. 789-796 CrossRef
- Zhang, Z, Kochhar, S, Grigorov, MG (2005) Descriptor-based protein remote homology identification. Protein Sci 14: pp. 431-444 CrossRef
- Rackovsky, S (2009) Sequenced physical properties encode the global organization of protein structure space. Proc. Natl Acad. Sci. USA 106: pp. 14345-14348 CrossRef
- Deiana, A, Giansanti, A (2010) Predictors of natively unfolded proteins: unanimous consensus score to detect a twilight zone between order and disorder in generic datasets. BMC Bioinforma 11: pp. 198 CrossRef
- Gromiha, MM (2009) Intrinsic relationship of amino acid composition/occurrence with topological parameters and protein folding rate. Open Struct. Biol. J 3: pp. 126 CrossRef
- Roy, S, Martinez, D, Platero, H, Lane, T, Werner-Washburne, M (2009) Exploiting amino acid composition for predicting protein-protein interactions. PLoS One 4: pp. e7813 CrossRef
- Antal, MA, Böde, C, Csermely, P (2009) Perturbation waves in proteins and protein networks: Applications of percolation and game theories in signaling and drug design. Curr. Protein Peptide Sci 10: pp. 161 CrossRef
- Johnson, KA (2008) Role of induced fit in enzyme specificity: a molecular forward/reverse switch. J Biol. Chem 283: pp. 26297-26301 CrossRef
- BRENDA (D Schomburg, Braunschweig, 2002)http://www.brenda-enzymes.org/. Accessed 27 December 2011
- UniProtKB (The UniProt Consortium, 2008)http://www.uniprot.org. Accessed 27 December 2011
- Bauer, C, Cercignani, G, Mura, GM, Paolini, M (2001) A unified theory of enzyme kinetics based upon the systematic analysis of the variations of kcat, KM, and kcat/KM and the relevant ΔG0≠ values—possible implications in chemotherapy and biotechnology. Biochem. Pharmacol 61: pp. 1049-1055 CrossRef
- Benner, SA (1989) Enzyme kinetics and molecular evolution. Chem. Rev 89: pp. 789-806 CrossRef
- Gasteiger, E, Gattiker, A, Hoogland, C, Ivanyi, I, Appel, RD, Bairoch, A (2003) ExPASy: the proteomics server for in-depth protein knowledge and analysis. Nucleic Acids Res 31: pp. 3784-3788 CrossRef
- Gromiha, MM, Thangakani, AM, Selvaraj, S (2006) Fold-rate: prediction of protein folding rates from amino acid sequence. Nucleic Acids Res 34: pp. W70-W74 CrossRef
- Arlot, S, Cellise, A (2010) A survey of cross-validation procedures for model selection. Stat. Surv 4: pp. 40-79 CrossRef
- O'Brien, RM (2007) A caution regarding rules of thumb for variance inflation factors. Qual. Quant 41: pp. 673-690 CrossRef
- Bhaskaran, R, Ponnuswamy, PK (1988) Positional flexibilities of amino acid residues in globular proteins. Int. J Pept. Protein Res 32: pp. 242-255
- Deleage, G, Roux, B (1987) Algorithm for protein secondary structure prediction based on class prediction. Protein Eng 1: pp. 289-294 CrossRef
- Zimmerman, JM, Eliezer, N, Simha, R (1968) The characterization of amino acid sequences in proteins by statistical methods. J Theor. Biol 21: pp. 170-201 CrossRef
- Lifson, S, Sander, C (1979) Nature 282: pp. 109 CrossRef
- Teusink, B, Passage, J, Reijenga, CA, Esgalhado, E, van der Wejden, CC, Schepper, M, Walsh, MC, Bakker, BM, Westerhoff, HV, Snoep, JL (2000) Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing Biochemistristy. Eur. J. Biochem 267: pp. 1 CrossRef
- van Eunen, K, Bouwman, J, Daran-Lapujade, P, Postmus, J, Canelas, AB, Mensonides, FIC, Orij, R, Tuzun, I, van den Brink, J, Smits, GJ, van Gulik, WM, Brul, S, Heijnen, JJ, de Winde, JH, de Mattos, MJT, Kettner, C, Nielsen, J, Westerhoff, HV, Bakker, BM (2010) Measuring enzyme activities under standardized in vivo-like conditions for systems biology. FEBS J 277: pp. 749 CrossRef
- Böde, C, Kovács, IA, Szalay, MS, Palotai, R, Korcsmáros, T, Csermely, P (2007) Network analysis of protein dynamics. FEBS Lett 281: pp. 2776-2782 CrossRef
- Li, KC (1997) Nonlinear confounding in high dimensional regression. Ann. Stat 25: pp. 577-612 CrossRef
- Yan, SM, Shi, DQ, Nong, H, Wu, G (2012) Predicting KM values of beta-glucosidases using cellobiose as substrate. Interdiscip. Sci. Comput. Life Sci 4: pp. 1-8 CrossRef
- Yan, SM, Wu, G (2011) Prediction of Michaelis-Menten constant of beta-glucosidases using nitrophenyl-beta-D-glucopyranoside as substrate. Protein Peptide Lett 18: pp. 1053 CrossRef
- Gabdoulline, RR, Stein, M, Wade, RC (2007) qPIPSA: relating enzymatic kinetic parameters and interaction fields. BMC Bioinforma 8: pp. 373 CrossRef
- Title
- Relationships between kinetic constants and the amino acid composition of enzymes from the yeast Saccharomyces cerevisiae glycolysis pathway
- Open Access
- Available under Open Access This content is freely available online to anyone, anywhere at any time.
- Journal
EURASIP Journal on Bioinformatics and Systems Biology
- Online Date
- August 2012
- 10.1186/1687-4153-2012-11
- Online ISSN
- 1687-4153
- Publisher
- Springer International Publishing AG
- Additional Links
- Topics
- Keywords
- Michaelis-Menten constant
- Turnover number
- Specificity constant
- Glycolytic enzymes
- Sequence-dependent properties
- Multivariate relationships
- Authors
- Peteris Zikmanis (1)
- Inara Kampenusa (1)
- Author Affiliations
- 1. Institute of Microbiology and Biotechnology, University of Latvia, Kronvalda Boulevard 4, Riga, LV-1010, Latvia


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Purchasing a Sailboat from the US?
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Re: Purchasing a Sailboat from the US?
HS, yes Providence airport is 30 to 45 mins away, depending. I'm not even sure you can get there on a direct flight from either Montreal or London, so that would add even more time.
One boat is owned by two families and they seem to timeshare. One comes for a couple of weeks straight and then the other. Their boat, by the way, is a shambles. They didn't even cover it over the winter. Long distance romance, I guess. But, I think they just use it as a foreign vacation cottage.
The other is a very nice Hallberg, kept in nice condition. They come from London and spend several long weekends and a few straight weeks throughout the summer.
As far as the Newport bridge, you should see the work they've done to add speed lanes to the toll plaza. The town father's have fully embraced collecting that money as fast as humanly possible.
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In the harsh marine environment, something is always in need of repair. Margaritas fix everything.
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6. Dogs Help with Weight Loss
According to a story published in The New York Times, research from the University of Missouri found that people who walk dogs are more consistent about regular exercise and show more improvement in fitness than people who walk with a human companion. In the 12-week study of 54 older adults, 35 people were assigned to a walking program for five days a week, while the remaining 19 served as a control group. Among the walkers, 23 selected a friend or spouse to serve as a regular walking partner, another 12 participants took a bus daily to a local animal shelter where they were assigned a dog to walk.
The researchers were surprised to find that the dog-walkers showed an impressive improvement in fitness, while the human walkers leaned towards making excuses to avoid the workout. Walking speed among the dog walkers increased by a whopping 28 percent, compared with just a 4 percent increase among the human walkers.
A University of Missouri-Columbia study showed that people who did not walk regularly could lose an average of 14 pounds in one year by walking a dog 20 minutes a day, 5 days a week!


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Written on: 20/10/2009
I just opened my cup soup packet to find a solid lump of gunk in it instead of powder! Moisture must have got into the packaging to have this effect therefore they people at Symingtons need to work on their packaging. Potentialy this product is not safe to eat.
What makes it worse is that they was no customer help info provided on the packaging or that I could find on the web to offer somekind of refund. They need to work on their packaging and their custommer service.
Previously I did find the soup quite tasty but will not be having it again.
As rated by our community of reviewers
" 1.2 inch bone and a ridiculous £10 voucher to "compensate" " Read More
" Tesco minestrone cup soup " Read More
Written by fallon8888
" Sizzling Sausage " Read More
" Gruel " Read More
" Not the same as I remember it, a pity, it was always good. " Read More


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Shaq didn't shy away from firing shots at Kendrick Perkins on air this week, as he took his Twitter beef with the big man onto national TV.
It all started with this tweet from Perkins during TNT's double header coverage of Miami-Chicago and Spurs – Golden State:
Do Shack ever stop talking about himself. SMH
— Kendrick Perkins (@KendrickPerkins) May 7, 2013
Wow @kendrickperkins is dominating2 PTs. When he gets 20 and 10 then ill stop talking about myself#worryaboutyourowngameandname
— SHAQ (@SHAQ) May 8, 2013
(as an aside – check out what Chuck says about Skip Bayless at 1:50! lol)
Via Ball Don't Lie.


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SAN ANTONIO -- Authorities believe a body found inside a car on the city's west side may be that of a Bexar County deputy who has been missing for a week.
The decomposed body was found Wednesday night inside Deputy John Salazar's blue Nissan Sentra. He has been missing since June 20.
The vehicle was parked in the parking lot of the Park Police training academy in the 5800 block of Old Highway 90.
The Bexar County Sheriff's Office said in a press release earlier this week that he was last seen running errands in the Las Palmas area on city's west side.
The body has been taken to medical examiner's office and will undergo an autopsy on Thursday.
An identity will not be released until the autopsy is complete.
Authorities did not comment on whether foul play or possible suicide was suspected.


text:
Lanza 1-Light Swing Arm Sconce
- Color:
- polished chrome
Please select an available size.
Please select a size.
Share This Item: Email
Description: Lanza 1-Light Swing Arm Sconce:
- From the Swingarm Collection
- Polished chrome finish
- Swing arm allows for custom adjustment
- Each requires one 100-watt 3 way bulb (not included)
- Measures 6 inches in width by 11 inches in height
- Dust with a dry cloth
This product is manufactured in compliance with U.S. standards. If product is to be used outside of the U.S., use only with the appropriate outlet adapter and voltage converter for your country. Do not plug into an electrical outlet higher than 110-120V as this could result in fire and/or injury.
Material: Metal
Care: Dust with a dry cloth
Brand: ELK
Origin: Imported


text:
The 4400: Season 3, Episode 1
The New World (11 Jun. 2006)
In a broadcast, the Nova Group promises the world a demonstration of their power on October 19. Tom and Diana apprehend Gary, but he refuses to give any information about October 19. ... See full summary »
Director:Vincent Misiano
Writers:Ira Steven Behr, René Echevarria (creator), 3 more credits »


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100 - 500 downloadsAdd this app to your lists
+ By Mystique
SecretVaultpro create an encrypted file and mount as a folder in your "/sdcard" folder. You can move sensitive docs, photos to SecretVaultpro folders/subfolders with your favorite file manager. SecretVaultpro unmount itself as a single encrypted file when you closed it.
Have you ever worried about your sensitive documents when you lost your mobile devices?
Note: An ads support SecretVaultpro is available free, the free version lack the ability to import Xml. The network access permission is strictly to retrieve ads from Admod, also a Google company.
If you like SecretVaultpro and like to buy me a beer, please support me by purchasing the paid version.
If you found bug on the app, please send me email so I can have it fix. I might not see it that way.
* Up to 5 times improvement in encryption performance with NG engine!
For more information and screenshot, please visit http://secretvaultpro.blogspot.sg/
Tags: secretvaultpro, secretvaultpro gratis, alternative to eds lite.
* New NG encryption, up to 5x performance!
No ads, no Internet access permission.
Improved Password Manager and Encrypted Notepad. Ability to import/export passwords and notes in Xml file. So you can import into other software or manually add more password by editing the Xml file. Ability to send password and notes to Email, Evernote and other applications.
GUI improvement for ICS and service updates.
The latest version is 2.9 c57, cipher update from c56 to support JellyBean.
(40 stars)
Good Truecrypt-like features. A little slow but appears to offer good security.


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Asus A8V & SATA2 Drives - I'm confused.
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Join Date: Apr 2007
Posts: 5
Asus A8V & SATA2 Drives - I'm confused.
A8V Deluxe motherboard
SATA2 Seagate Barracuda 320GB HDD
I currently have 2 IDE HDD already in the machine. These I wish to retain and one of them set as the primary/boot device on XP Pro. I wish to add the SATA drive (a single drive) purely as a data drive.
OK. So my research indicates that this motherboard is not SATA2 compatible but is SATA1. The drive is SATA2. I've read that I can jumper the throughput to 1.5Gb/s and this should work. No problem there. The confusion comes in when I go into the BIOS.
The A8V motherboard has 4 SATA connectors. 2 x SATA and 2 x SATA RAID.
No to achieve the above scenario, which connectors do I use on the motherboard?
Then, in the BIOS, there are two SATA settings (3 actually, but one is a subsetting)
- OnChip SATA boot ROM
- OnBoard Promise Controller
>Operating Mode [RAID Mode/IDE Mode]
Enabling either or both of these with/withou IDE/RAID and trying different physical connectors on the Motherboard doesn't seem to detect the drive at all. I'm not sure if I have missed a configuration or not performed something to get it to work. As I only have one SATA drive I can't even tell if the drive itself is the problem.
Can anyone please tell me the BIOS settings, the process (i.e. connect drive, reset BIOS etc) and connectors I should be using. It takes so long when the drive isn't detected I haven't been able to find a solution.
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NEW YORK (TheStreet) -- The S&P 500 hit 2,000 for the first time in its history but closed short of that mark, up 0.43% to 1,997.92.
On CNBC's "Fast Money" TV show, the trading panel took a closer look at the market.
Read More: Warren Buffett's Top 10 Dividend Stocks
Steve Grasso, director of institutional sales at Stuart Frankel, advised investors to never "short a dull market." A 10% correction isn't coming anytime soon and the S&P 500 is on track to hit 2,100 by year's end.Tim Seymour, managing partner of Triogem Asset Management, said he likes financials for three reasons: The sector has lagged the broader market, individual companies are returning to normalized earnings and the economy appears to be accelerating. If the economy does pick up, interest rates are likely to climb, which will be good for the banks. Seymour owns Bank of America (BAC) and Citigroup (C) . Pete Najarian, co-founder of optionmonster.com and trademonster.com, said there doesn't seem to be much fear in the market and many individual financial stocks seem to have room to the upside. He pointed out the bullish options activity in the Financial Select Sector SPDR ETF (XLF) , specifically in the December $24 call options. Guy Adami, managing director of stockmonster.com, said he continues to like the health care sector. The broader market seems likely to run higher, he added. The panel was asked what their top buy and sell candidates are: Seymour is a buyer of Baidu (BIDU) and a seller of the Utilities Select Sector SPDR ETF (XLU) . Najarian likes transport stocks, such as airlines, as well as Goldman Sachs (GS) on the long side. He is a seller of Netflix (NFLX) and is looking for a pullback toward the 200-day simple moving average. Grasso is a buyer of KB Home (KBH) and a seller of Exxon Mobil (XOM) . Read More: Roche Investors Should Breathe Easier After InterMune Acquisition Adami is a buyer of Celgene (CELG) and is taking profits in Home Depot (HD) , adding that it could pull back to $84.
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Cheap ANV to Las Vegas flights
Popular Flights from Anvik, Alaska
Top Anvik Flights to US Destinations
Popular Flights from Las Vegas, Nevada
Top Las Vegas Flights to US Destinations
Top Las Vegas International Destinations
ANV to LAS Route Map
Anvik to Las Vegas Flights, Stats and Airplanes
Route information for flights from Anvik AK to McCarran Intl..
2,641.70 miles
LAS - McCarran Intl. Airlines
Browse the most popular airlines servicing the Las Vegas (LAS) airport. Visit their flights pages to learn more about the most popular routes these carriers fly.


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Question: Garcinia cambogia make you urinate frequently .because i have to go every hour
Age: 60 Gender: female
Conditions: Going Frequently To The Bathroom
Medications: Garcinia Cambogia
Number of patients like blanca on eHealthMe: 57
Personalized health information: on eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 66 million people have used us. 200+ peer-reviewed medical journals have referenced our original studies. Start now >>>
I started taking garcinia cambogia in about a month ago and I'm taking 3000 milligrams a day is it making me go a lot to the bathroom I have to go every hour it's driving me crazy.so I went to the doctor I thought I had urinated tract infection but they said no but I'm still going to bathroom a lot and it started with the vitamins.should I stop taking them.thank you can you help me
Replies (subscribe to this Q&A):
3000 mg per day is way too high. Dr. Oz and Dr. Chen recommend 1500 mg per day. I am urinating more than usual and I am taking 1300 mg per day. Just started so no real weight loss measurements yet.
You can also ask your question in a related mobile support group:
- support group for people who take Garcinia Cambogia
Related topics: Garcinia Cambogia
Can you answer these questions (Ask a question):
- Can i use garcinia cambogia if on levothyroxine treatment, (2 answers)
Due to my Hypothyroidism I have gained wait and cannot seem to lose it no matter how much I exercise. I gained 30 pounds in one year after weighing 120 for 60 years. The added weight makes me very uncomfortable.


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Nitish Kumar today chose senior minister Jitan Ram Manjhi to succeed him as Bihar Chief Minister, who would stake claim to form the government.
The 68-year-old Manjhi, a dalit leader, was SC & ST minister in the Nitish Kumar government.
The JD(U) has staked claim to form the government in the state under Manjhi, Kumar said.
Manjhi's name, he said, has the approval of JD(U) President Sharad Yadav as well state party chief Basistha Narayan Singh.
"We have staked claim before Governor D Y Patil to form the government under leadership of Jitan Ram Manjhi," outgoing Chief Minister Nitish Kumar told reporters outside Raj Bhawan.
He said "We have handed over a list of support of 117 JD(U) MLAs, 2 Independents and 1 CPI member totalling 120 to the Governor for formation of the new government." Asked for the reason for choosing Manjhi as his successor, Kumar said "he is experienced and his contribution to the party is immense."
The effective strength of the House at present is 239.
JD(U) has 117 members, BJP 90, RJD 21, Congress 4 and others including Independents 1 CPI member 7.
The four-member Congress, which voted for the Nitish Kumar government in the trust motion in June last year has authorised party High Command to decide on the future course of action.


text:
The government says phone and email traffic is not protected by the Fourth Amendment, and does not require a court warrant to search. The logic is based on a 1978 case that has been hauled out regularly to justify acquisition of third-party information. But does that logic apply to bulk collection of the sort that's at the heart of the debate over NSA surveillance?
Source: NPR
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1606 Bellevue Way Se ( )
Bellevue, WA 98004-7193
Neighborhoods: West BellevueView Hours
1606 Bellevue Way Se ( )
Bellevue, WA 98004-7193
Neighborhoods: West BellevueView Hours
February 20, 20075.0
I came back to Chace's to try out more selections from their fine breakfast and pancake menu, and I was definitely not disappointed. It's a good idea to come early during the busy weekend brunch hours, as there isn't a lot of seating for how crowded it can get.
My follow-up review for this restaurant. Read my previous review for this restaurant here
February 1, 20075.0
My wife and I call this "The Happy Pancake Place" because after eating here you will be full and happy! They have amazing potato pancakes with sour creme, german sausages, strawberry belgian waffles… the list goes on and on, but so far those are our favs. I think they've been around for 40 years or so. We ran into an elderly couple who've been going there for over 20 years… yes, it's that good. :)
Cooked to perfection. light, and fluffy with crispy edges. melt in your mouth! Best with sour creme topping.
October 14, 20075.0
I read the comments about this resturant this morning, so my husband and I decided to check this place out. I ordered the strawberry pancakes… one bite feels like an angel just kissed you. The parking isnt great and you're a little cramped in but its well worth it!! My husband and I decided that if we're going to have any friends or family come in to visit we're going to take them to Chaces Pancake Corral. Its our new favorite place to eat.
July 17, 20075.0
I always enjoyed coming here. The restaurant gives off a warm home feeling and is great place for quick meal. The hours are great for morning people. parking and seating is not very friendly.
Out of the pancakes I've tried… I enjoy the strawberry pancake the most…
October 16, 20064.0
This place had good pancakes. The staff was friendly and service was quick. The seating area is cramped and to quote my husbad "there is not enough space for big people to walk."
August 5, 2011
Guys. You might have lines at breakfast time but don't think its for good food. There is no other breakfast place in this part of Bellevue to go to. Better to eat ceral at home. Don't waste your $$ or time. Service with attitude and…
September 17, 2009
if you have not ate here you are missing out!! my buddy and i ate here after a long night and were BLOWN AWAY!!great service, a nice clientèle, and FANTASTIC food. chaces is my new favorite breakfast location!! i hopped right out of ihop…
July 13, 2009
Great food! You can't go wrong. They are small old restaurant that really know how to serve breakfast. Great value.
These dishes from the Chace's Pancake Corral menu are contributed by Menuism users directly, as part of a restaurant review, or as part of an image upload.


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Half of the new jobs are likely to be in Scotland.
Maersk Oil and BG Group said the proposed reforms to the oil and gas tax regime, involving a new allowance for ultra High Pressure High Temperature (HPHT) fields will enable the development of two new projects, leading to investment of £6bn across new fields.
Chancellor George Osborne said: "Backing businesses, who in turn create jobs, is part of our long-term plan to fix the economy. The Government's continued support for the oil and gas industry has led to billions of pounds of investment and tens of thousands of jobs across the country."
His Liberal Democrat deputy, Danny Alexander, who today will open Maersk Oil's new offices in Aberdeen, added: "Each new job will mean more security for another family and this shows how the UK Government is supporting one of Scotland's most important industries."
Jakob Thomasen, Maersk Oil's Chief Executive, described the proposed HPHT allowance as a welcome boost to new projects, which could contribute to energy security, jobs and the economy.


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This traditional Irish favorite is a one-pot, complete meal that is so easy to prepare, you won't want to save it for just the wearing o' the green.
1 corned beef brisket, trimmed (3 pounds)
1 small onion, quartered
2 tablespoons McCormick® Mixed Pickling Spice
1 teaspoon McCormick® Garlic, Minced
8 small red potatoes
2 cups baby carrots or 8 carrots, peeled and cut into 1 1/2-inch pieces
1 small head cabbage, cored and cut into 8 wedges
2 tablespoons butter, melted
1 teaspoon McCormick® Parsley Flakes
Place brisket in 6-quart saucepot or Dutch oven. Cover with about 2 quarts water. Add onion, pickling spice and garlic; cover.
Bring just to boil. Reduce heat to low; cover and simmer 2 hours. (Do not boil.) Add potatoes and carrots; simmer 30 minutes longer. Add cabbage; simmer 15 minutes longer. Remove brisket and vegetables from saucepot.
Slice brisket across the grain. Mix butter and parsley; brush on vegetables.
(Amount per serving)
I had No idea How to Cook Corned Beef And Cabbage,And I had already put Mine in the Slow Cooker at 5pm to Slow Cook in the Slow Cooker for Ten Hours.McCormick showed Me How to Put it in One Pot,What to add & How to Spice it And Be done and Eating in Less Time! I was amazed.Next Time I will check McCormick First.
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I'm searching for phrases to describe Phases of the Moon Music & Art Festival. It began as a dark side of the moon, but that was just a phase. As an audience, our hackles were already up, howling at the moon before the weekend ever arrived. Through no fault of the Phases organizers, RatDog had to cancel their appearance. Bobby Weir's lightening is lazy.
Although there's no camping at Bumbershoot, the crowd looks funkier than yesterday. I pass many familiar faces strolling around Seattle Center; they may be reapplied with make-up or flourished with new clothes, but no amount of blush can mask the wear and tear of an all-nighter. I get the sense that, even if it wasn't 80 degrees and sunny, people would still be wearing their shades.
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Facing the malpractice crisis: academic physicians' willingness to accept quick fix solutions.
Methods: We surveyed all 270 Department of Medicine physicians at a large academic center. Respondents were asked about their knowledge regarding malpractice premiums, willingness to reduce patient-care activities and accept decreases in compensation.
Results: The response rate was 80%. Respondents estimated the annual increase in malpractice premiums from 2004 to 2005 to be 29%. The true increase was 28% (P = 0.55). Almost all opposed eliminating patient care (95%) or providing patient care every other year at double effort and withdrawing from patient care on alternate years (97%). Seventy percent would limit their clinical procedures. Most physicians opposed salary reduction (97%) or decreases in fringe benefits (99%).
Conclusions: Few academic physicians are willing to limit patient care or accept decreases in compensation to recoup institutional malpractice costs.
Key Words: medical malpractice, academic medical centers, physician compensation
Research, teaching, and patient care encompass the core mission of academic medical centers; however, increasing malpractice rates may threaten this mission. (1) Current efforts to address the crisis have focused primarily on tort reform. This involves complicated legal processes, multiple stakeholders, and will take time to result in meaningful change. (2-4) In the interim, academic medical centers are faced with the challenge of paying rapidly escalating malpractice premiums. Because of the unique setting in which academic medical centers provide care, creative ways to manage the malpractice crisis may be needed until more long-term solutions are developed. Consideration for the academic physician as clinician, teacher and investigator will need to be paramount. Possible quick fix solutions might involve eliminating patient care responsibilities for faculty who spend the majority of their time in nonclinical roles or reducing salaries and fringe benefits.
The purpose of this study was to determine the willingness of physicians at a large academic medical center to accept various strategies designed to rapidly contain institutional malpractice costs.
Study Administration
In May 2004 we surveyed all 270 clinically active physician faculty in the Department of Medicine at Johns Hopkins University School of Medicine (Johns Hopkins Hospital and Johns Hopkins Bayview Medical Center). Up to two follow-up contacts were sent to encourage full participation. The study was approved by the Johns Hopkins Medicine Institutional Review Board.
Survey Content
We developed a 27-item questionnaire. The survey obtained information on participants' personal and professional characteristics, their estimates of current malpractice fees, attitudes about malpractice premiums and willingness to accept changes to their clinical practice and compensation (salary and benefits) in an effort to reduce institutional malpractice costs. Questions were formatted as multiple choice, short answer, yes/no and 5-point Likert scales.
Statistical Analysis
Descriptive statistics were used to characterize physician demographics and responses. Responses to 5-point Likert scales were dichotomized and analyzed as proportions. t tests were used to compare physician responses with actual malpractice premium values. Data were analyzed using Stata Statistical Software: 8.2 (Stata Corp., College Station, TX, 2004).
Respondent Characteristics
Two-hundred and seventeen faculty completed the survey for an 80% response rate. Fifteen respondents were excluded from the analysis because they spent 0% of their time in patient care. The personal and professional characteristics of the respondents are presented in the Table. Thirty percent of the faculty spent 50% or more of their time on patient care. There were no significant differences between respondents and nonrespondents in terms of gender and rank (P > 0.05).
Knowledge and Attitudes About Current Malpractice Rates
Almost all respondents (99%) correctly reported that malpractice rates for the institution had increased in the last year. Respondents estimated the annual increase in malpractice premiums to be 29% from 2004 to 2005. The true premium increase was 28% (P = 0.55). Faculty estimated the mean rate per physician in the Department of Medicine in 2004 at $13,724.50: the actual mean rate was $10,453 (P < 0.001).
Most faculty believed that the following factors place academic medical centers at a greater risk for malpractice claims compared with nonacademic hospitals: higher expectations from patients and society (81%), sicker patients (81%) and the presence of trainees (62%). Forty-one percent of physicians in our sample thought that escalating malpractice premiums was the most important financial challenge facing academic medical centers.
Willingness to Accept Reductions In Patient Care Responsibility, Salary and Benefits
When asked if they would be willing to give up patient care responsibilities completely, almost all physicians opposed or strongly opposed this measure (95%), (Fig.). A similar number opposed or strongly opposed the option of providing patient care every other year at double the effort and withdrawing from patient care on alternate years (97%). Seventy percent of respondents were willing to limit their clinical procedures to only those that they regularly performed. Almost all physicians opposed or strongly opposed salary reductions (97%) and decreases in fringe benefits (99%) as ways to help the institution cover escalating malpractice costs.
Academic physicians in our study appear to be aware of the magnitude of the current malpractice crisis. Almost all knew that costs were increasing. Many reported that increasing malpractice costs represent the most important financial challenge facing academic medical centers. Despite this knowledge, very few were willing to limit or eliminate patient care activities or accept a decrease in salary or benefits in an effort to help recoup institutional malpractice costs.
To our knowledge, this is the first survey asking academic physicians what changes they would be willing to make in response to the malpractice crisis. One possible explanation for this unwillingness to limit or give up clinical roles may be that academic physicians recognize and are committed to their unique roles as clinicians, teachers and investigators. Another reason may be that academic physicians remain relatively cushioned from the pressure of increasing malpractice costs because they do not pay their own premiums. In contrast, many private physicians who must pay their own malpractice premiums, have responded to increases in malpractice costs by limiting or relocating their practices or retiring from clinical medicine. (5,6)
Physicians in our study were even less likely to accept decreases in salary or benefits in an effort to defray institutional malpractice costs. It is well documented that the salaries of academic physicians are lower than those of doctors in private practice. (7) Fringe benefits, including malpractice coverage, may reduce the magnitude of the discrepancy in salaries. Furthermore, the potential solutions proposed in our study are not without limitations. For example, faculty who conduct clinical research but who may not care for their own patients would still require malpractice coverage.
The academic physicians in our study believed that many factors place them at a greater risk for being sued than non-academic physicians, such as higher societal expectations, sicker patients and the presence of residents and fellows. The complex structure and multiple functions of academic medical centers create unique liability issues and the literature shows that litigation, including malpractice claims, has increased over the last half century. (8) Existing efforts to reduce the risk of litigation including systems approaches to enhance patient safety and reforms to graduate medical education may help control malpractice costs in the long term but are unlikely to have immediate effects. (9-11) However, if malpractice premiums continue to account for an increasing percentage of clinical income generated at academic institutions, academic physicians may no longer feel as sheltered from these costs. (1)
Several limitations of this study should be considered. First, our survey posed hypothetical questions. Faculty may have chosen different responses under more pressing real-life circumstances. Second, although we had a high response rate from faculty at a large institution, our findings may not be representative of the experiences of faculty in other departments or at other academic institutions. The Johns Hopkins Institutions are insured as part of an academic group consortium, and therefore, our malpractice premiums may not reflect national trends. Finally, we were unable to make comparisons based on amount of time spent in patient care due to the size of our sample. However, because of the high response rate, the percentage of faculty willing to accept the changes proposed in the survey would be unlikely to change even with a larger sample.
While academic physicians are aware of the magnitude of the current malpractice crisis, very few are willing to limit or eliminate patient care activities or accept a decrease in salary or benefits in an effort to help cover institutional malpractice costs at this time. Understanding physicians' perspectives will be important as academic medical centers consider potential quick fix solutions to address the rapidly rising costs of malpractice premiums.
Dr. Wright is an Arnold P. Gold Associate Professor of Medicine. Drs. Kravet and Wright receive support as Miller-Coulson Family Scholars through the Johns Hopkins Center for Innovative Medicine.
1. Brody WR. Dispelling Malpractice Myths. Washington, DC, The Washington Post, November 14, 2004.
2. Mello MM, Studdert DM, Brennan TA. The new medical malpractice crisis. N Engl J Med 2003;348:2281-2284.
3. Studdert DM, Mello MM, Brennan TA. Medical malpractice. N Engl J Med 2004;350:283-292.
4. Kessler DP, Sage WM, Becker DJ. Impact of malpractice reforms on the supply of physician services. JAMA 2005;293:2618-2625.
5. Rice B. Hospitals feel the malpractice pain. Med Econ 2003;80:37-38.
6. Brehm J, Hannah K, Ruddick P, et al. Physician supply in key medical specialties in West Virginia hospitals, 2001-2004. W V Med J 2004; 100:132-135.
7. Academic Practice Compensation and Production Survey for Faculty and Management: 2004 Report Based on 2003 Data. Medical Group Management Association, 2004.
8. Helms LB, Helms CM. Litigation involving medical faculty and academic medical centers, 1950-1991. Acad Med 1993;68:7-19.
9. Brennan TA, Mello MM. Patient safety and medical malpractice: a case study. Ann Intern Med 2003;139:267-273.
10. Kachalia A, Studdert DM. Professional liability issues in graduate medical education. JAMA 2004;292:1051-1056.
11. Schoenbaum SC, Bovbjerg RR. Malpractice reform must include steps to prevent medical injury. Ann Intern Med 2004;140:51-53.
Rachel B. Levine, MD, MPH, Steven J. Kravet, MD, Darcy A. Reed, MD, MPH, Donna M. Windish, MD, MPH, Leah Wolfe, MD, and Scott M. Wright, MD
From the Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, Baltimore, MD; the Division of Primary Care Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN; and the Department of Internal Medicine, Yale University School of Medicine, New Haven, CT.
Reprint requests to Rachel B. Levine, Division of General Internal Medicine, Johns Hopkins Bayview Medical Center, B2N, Rom 235, 4940 Eastern Avenue, Baltimore, MD 21224. Email: firstname.lastname@example.com
Accepted March 15, 2006.
RELATED ARTICLE: Key Points
* Increasing malpractice costs may limit the ability of academic medical centers to fulfill their commitment to research, teaching, and patient care.
* Academic physicians appear to be aware of the magnitude of the current malpractice crisis.
* Very few academic physicians are willing to significantly limit or eliminate patient care activities or accept decreases in salary or benefits in an effort to help contain institutional malpractice costs.
Table. Characteristics of the 202 Department of Medicine faculty physician respondents Characteristics Mean age +/- SD, yr 46.0 +/- 9.8 Women, n (%) 61 (30.0%) Academic rank Instructor, n (%) 19 (9.4%) Assistant Professor, n (%) 81 (40.1%) Associate Professor, n (%) 52 (25.7%) Professor, n (%) 50 (24.7%) Average percentage of time spent in research and patient care Research 39.5% Direct patient care (no learners present) 21.0% Supervising patient care (learners present) 18.3%
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Ramblings on about natural perfumery, perfumery raw materials, daily grind, and anything else that needs to come out.
Sunday, September 06, 2009
LPR Contest/Giveaway!
The September/October sponsor for Le Parfumeur Rebelle's giveaway is me ~ The Scented Djinn. I put up the first of three bathing kits in the Harem Skincare line-up ~ Karima Skin Care Kit. Please enter the giveaway. You can enter anonymously, which just means LPR won't publish your name as the winner. Enter! Enter! Enter!
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Keiko Abe Marimba Scores, Parts: 1 items found
Works for Marimba Duo
(Performance Score). Composed by Keiko Abe. For Marimba. Percussion. 24 pages. Schott Music #SJ052. Published by Schott Music (HL.49013538)
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2 women accused of staging fake funerals
LOS ANGELES It was quite a send-off for Jim Davis, or so the people paying his funeral bills were led to believe.
They were told Davis was laid to rest at Abbey Memorial Park in Compton after being placed in an ornate, top-of-the-line casket lined with elaborate floral arrangements. Altogether, the bill to bury Davis at the palm-lined cemetery came to nearly $31,000.
But there was a problem: There was no Jim Davis. He was dreamed up by a group of scam artists, authorities say.
And prosecutors say the coffin that was lowered into the ground was made out of cheap plywood or cardboard, filled with either rocks or butchered meat and animal bones, apparently to convince those who handled it that there was a body inside.
Faye Shilling, 60, and Jean Crump, 67, were indicted last week on federal charges that they scammed insurance companies and funeral-related businesses out of as much as $1 million by taking out policies on fictitious people and then staging their funerals.
Two other women previously pleaded guilty in the case. The indictment lists just two fabricated deaths, but authorities said there may have been as many as seven.
The participants went so far as to file phony death certificates, and bought a $3,354 burial plot for "Jim Davis," investigators said. Davis was the only one "buried." The others were supposedly cremated, evidently because that was easier to pull off.
"The allegations, if true, are quite shocking," federal prosecutor Anthony Montero said Monday after Shilling and Crump pleaded not guilty to fraud. "It does demonstrate an enormous level of deception and a commitment to hide their fraud."
The women were freed on $10,000 bail. In a telephone interview with The Associated Press, Shilling said: "I am hurt, just hearing things that I know are not true. Someone is trying to destroy me, but why?"
The prosecutor said a small group of mourners attended Davis' graveside service in 2006, but he would not say who they were. He said he did not know whether a clergyman officiated or anyone gave a eulogy.
The scheme began coming apart several weeks after the funeral, when an insurance investigator began snooping around, the prosecutor said. He said the participants panicked and dug up the coffin, claiming later that they had had Davis' remains cremated and scattered at sea.
Lydia Eileen Pearce, 37, owner of the Steward-Pearce Mortuary in Long Beach, and Barbara Lynn, 54, a notary, previously pleaded guilty to fraud and face as much as 20 years in prison when sentenced. Montero said more arrests are possible.
He said the women used their knowledge of the insurance and funeral industries to pull off the ruse.
"How else are you going to get a coffin buried with no body in there?" the prosecutor asked.
As a phlebotomist, Shilling drew blood from people applying for insurance, Montero said, which gave her expertise in how such policies are set up and paid out. Crump worked in a now-defunct Long Beach mortuary.
In the case of "Jim Davis," prosecutors said the women persuaded two insurance companies to issue policies on his life worth a total of $700,000. A doctor was also allegedly offered $50,000 to create a fake medical history for him. But the prosecutor would not say whether the doctor took the money.


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"This collaboration is a natural strategic fit for MonoSol Rx and our PharmFilm® technology," commented A. Mark Schobel, President and Chief Executive Officer, MonoSol Rx. "KemPharm is a true pharmaceutical innovator, and through the combination of KP106 and PharmFilm®, there is the potential to introduce a novel ADHD product that could represent a safer, more convenient treatment option for ADHD patients. We look forward to working together to maximize the commercial potential of KP106 through this partnership."
About KP106
KP106, KemPharm's lead prodrug candidate for the treatment of ADHD, is composed of d-amphetamine and a ligand. In clinical studies, KP106 demonstrated pharmacokinetics indicative of an attenuated amphetamine exposure as compared to Vyvanse®. These data suggest that patients receiving KP106 may experience decreased side effects and decreased risk of abuse typically associated with stimulants. In addition, KemPharm is positioning KP106 to be the first ever proprietary oral film dosage form for ADHD. KemPharm projects the filing of a new drug application (NDA) for KP106 in 1H2013.
About KemPharm, Inc.
KemPharm, Inc. is focused on the discovery and development of new chemical entities (NCEs) to treat serious medical conditions through its proprietary and broadly applicable LAT prodrug approach. KemPharm utilizes its LAT prodrug technology to generate improved versions of FDA-approved drugs. The Company's business strategy includes seeking strategic development partners following rapid clinical proof of concept demonstration in a Phase 1 trial. KemPharm also plans to explore discovery stage alliances with industry leaders, leveraging its prodrug know-how and LAT technology. KemPharm is developing candidates for ADHD, pain, other central
|SOURCE KemPharm, Inc.
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and not the uber-sacrosanct unquestionalable Chosen by God Nation State that is immaculately conceived and preserved from all sin both original and actual that exists in the fever dreams far too many Americans.
Today's Reminder that Israel is Just a Secular Nation State
Related posts from Catholic and Enjoying It!:
- MikeTheGeek
Although I agree w/ your premise that the modern nation state of Israel is not necessarily (or even likely) the end-times Israel of scripture, the publishing of Playboy doesn't make the point. The original Israel, rather by definition the Chosen of the day, weren't exactly models of purity either. Their nation had the same misfortune as the current one (and ours, for that matter) in that it was made up of humans.
- Rosemarie
I also agree with that premise and do not consider Israel above criticism. But I wonder whether the Evangelical view of Israel's special chosen-of God status and alleged role in end times prophecy necessitates that it be a perfectly holy nation. IIRC from my Evangelical days, we were told that the nation of Israel would at first fall for the Antichrist's deception. They would sign a peace treaty with him and he in turn would make it possible for them to rebuild the ancient temple. They wouldn't see him for what he really is until he marches into that temple on its day of dedication and declares himself a god. At some point after the Beast screws them over, the Israelis finally come to recognize Jesus as the true Messiah. So if (according to Evangelical eschatology), Israel can at first mistake the Antichrist for a good guy, why couldn't the country also have sinful stuff like prôn0graphy?
- Mark Hartman
Agreed; but it is also the closest thing to a Western democracy that exists in the Middle East, and as such it's much easier to relate to, discuss with, and have an alliance on mutually-understood terms with. But we should remember that Israel's first priorities will involve the security of Israel, not the security of the USA, and we should have the same priorities here at home.
- Dan C
Does everyone within the borders of the State of Israel have voting rights?
- John H.
Dan C. No, not everyone within the Nation of Israel has voting rights.. Only those who pledge to recognize the state of Israel as such have voting rights. Other people are non-voting permanent residents (mostly Arab Muslims and Christians).
- Rhinestone Suderman
Hmmm. . . does that mean we can stop funneling American tax dollars to Pakistan, Egypt and the Palestinians?
Naaaaah. . . those guys really are "Uber sacrosanct"!
- Mark Shea
Absolutely we should stop giving them money. We are broke.
- Kirt Higdon
Israel has numerous religious and secular elements and factions. The former have been gradually increasing in influence due to a high birth rate and more dedication, but the recent elections gave evidence of a secular backlash which may be gaining strength. Neither a secular nor a religious Israel has any claim on US military aid or support, nor do Pakistan, Egypt, the Palestinians, the Syrian rebels, etc. etc.
- John C
Wow! Playboy has been a tired old rag since the seventies. This guy Pomerantz is really cutting edge!


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Sam Smith - Nirvana (Harry Fraud Remix)
Artist: Sam Smith
Featuring: Harry Fraud
Producer: Harry Fraud
Album: None (Promo Single)
Avg Rating: 3.0 ( 2 votes )
Back in August of 2013, London singer-songwriter Sam Smith stepped into the Booth with Nirvana, a slow-burning ballad that won high praise from our readership. UK beatsmith Two Inch Punch subsequently remixed the cut, but was unable to match the Craze & Hoax-produced original's lofty 4.25-star average rating. Now, Harry Fraud has thrown his hat into the ring. While the Brooklyn beatmaker's rendition sticks closer to the source material than TIP's Promised Land Remix, it nonetheless incorporates a few unique touches, including the subtle use of trap-style hi-hat rolls. Does this rendition measure up its prototype? Debate away—and, if you haven't already, be sure to check out Smith's more recent single selections, Money on My Mind and Make It to Me.
Sam SmithHarry Fraud R&B/PopClub
Written by richard on Jan 22, 2014
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How do you know the Bible is true?
That's an excellent question because so much is at stake in the Christian faith in terms of the truthfulness of Scripture. The Bible is our primary source of information about Jesus and about all of those things we embrace as …Read More
How were the books of the Bible selected and compiled, and how were the decisions made as to what would be distributed as the Word of God?
Even though we think of the Bible as being one book, it's actually a collection of sixty-six books, and we realize that there was a historical process by which those particular books were gathered together and placed in one volume …Read More
What is your opinion of abortion, and are there any Scriptures that would back it up?
We are all aware of hellfire-and-damnation preachers who rave and scream about the decadence of the world. It can become tiresome to listen to all of that. I think we all respect people who can disagree with others in a …Read More
What should make Christian marriages distinctive?
When we talk about the difference that being a Christian makes in life, not just in marriage, we point to the reality that as Christians we are indwelt by God the Holy Spirit, who is working within us to give …Read More
If justification is by faith alone, how can we apply James 2:24, which says a person is justified by what he does, not his faith alone?
That question is not critical only today, but it was in the eye of the storm we call the Protestant Reformation that swept through and divided the Christian church in the sixteenth century. Martin Luther declared his position: Justification is …Read More
Does the Bible tell us what heaven will be like?
When I was in seminary, I studied under an extremely learned professor who I was convinced at the time knew the answer to every possible theological question. I remember I was so in awe of him that I asked him …Read More
What is the biblical basis for human dignity?
As a Christian I do not believe that human beings have intrinsic dignity. I am totally committed to the idea that human beings have dignity, but the question is, Is it intrinsic or extrinsic? Dignity, by biblical definition, is tied …Read More
When did God decide to give us eternal life?
When is a time word, and the Bible uses words like that. And when the Bible speaks about the time frame in which God's decision is made in respect to our eternal life, it generally puts the decision at the …Read More
Is God concerned with the material well-being of Christians?
The short answer to that, emphatically and definitely, is yes. Not only is God concerned about the material well-being of Christians, he's deeply and profoundly concerned for the material well-being of the whole world. God created a material world. He …Read More
What does the Apostles' Creed mean when it says that Jesus descended into hell?
The Apostles' Creed is used as an integral form of worship in many Christian bodies. One of the more puzzling statements in that creed is: [Jesus] descended into hell. First of all, we have to look at the creed from …Read More
What can Christians expect from God in regard to healing?
I don't know how many times I've seen on the walls of pastors' studies or in Christian homes the little sign, Expect a Miracle. If a miracle is something we can expect, like we expect the postman every morning, it …Read More
In the case of a terminally ill person, who should decide when to discontinue life-support systems — to "pull the plug"?
Last year I addressed eight hundred physicians at the University of Alabama in Birmingham. I was asked to address that precise question: How you decide when to pull the plug? I was also interested to note that the largest single …Read More
What is the relationship between a Christian education and a public education?
In recent years we have seen the beginnings of sectarian schools in numbers that are unprecedented in American history—save for the manifestation of parochial schools sponsored by the Roman Catholic Church. In the case of Catholic theology and practice, the …Read More
As a minister, would you marry a believer and a nonbeliever?
The basis for your question obviously is the biblical text that says we ought not to be yoked unequally with unbelievers. The assumption, of course, is that this text has direct reference to marriage. The Bible doesn't explicitly say that. …Read More
Both Peter and Paul call us to submit to governing authorities. In light of that, is revolution ever possible for a Christian, and if so, under what circumstances?
It certainly is clear that the New Testament puts an emphasis on the Christian's responsibility to be a model of civil obedience. In Romans 13, Paul tells us that the powers that be are ordained by God. That doesn't mean …Read More
Questions AnsweredHere you'll find responses to numerous questions R.C Sproul has been asked over the years.
- All
- Atonement
- God
- Heaven and Hell
- The Holy Spirit
- Jesus Christ
- Last Things
- Man and Sin
- Sacraments
- Salvation
- Systematic Theology
- Apologetics
- Christianity and Culture
- Ethics
- Philosophy
- Bible Interpretation
- Bibles
- Controversies in the Church
- Marriage and Family
- Practical Theology
- Spiritual Growth
- Sanctification and Growth


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Four Seasons Dubai to launch in time for Christmas
Four Seasons Resort Dubai at Jumeirah Beach is targeting a December 1 launch.
The 14-acre luxury resort has a Spanish-Mediterranean feel with Arabian accents and the 237-room hotel offers panoramic sea views and large balconies.
The lobby is capped by an octagonal dome finished with gold leaf and no expense has been spared – even the handrails in the elevators are made of Murano glass, and the opulence extends to the two 510sqm Presidential Suites and Royal Suite.
Four Seasons believes the resort's positioning – located on the Jumeirah beach and not far from the city centre – will appeal to business and leisure travellers alike. The spa will offer a full menu of traditional rituals and each of the 10 treatment rooms will open up onto a discreet outdoor space.
Ten F&B venues will be available, half managed by Four Seasons and half independent.
Suq will be a market-style restaurant with three open kitchens; the pool grill Sea Fu will transform into an open air fine seafood restaurant each evening; the Shai Salon – meaning "tea" in Arabic – will be a meeting spot by the main entrance and near the gardens; and the Hendricks Bar is fashioned as a traditional club, with leather-panelled oak walls, deep chairs and a cigar room.
The sixth floor rooftop Mercury Lounge will be the see-and-be-seen place, where private majlises with exclusive alcove seating offer views of Burj Khalifa and Burj Al Arab. Executive chef Gilles Arzur will oversee the food and there will be two concepts by celebrity chef Jean-Georges Vongerichten, two additional venues by Zuma restaurants, and the Provocateur Night Club, a small and exclusive lounge featuring top international DJs.
MICE will be a key sector with 1,199sqm of event space available, hosting everything from society galas to beachfront weddings.
Top Headlines
- Gazans reach beyond Israeli blockade through start-up
- France is playing a risky dating game in the Gulf: experts
- Egyptian stocks plummet as Yemen confict deepens
- Mission to Mars: UAE plans Arab region's first unmanned probe
- Supervising the stoners: Egyptian tobacco traders call for the legalization of cannabis
- Halfway around the world for 27 dollars?! From Dubai, anything is possible this holiday season
- Four Points by Sheraton Downtown Dubai
- four seasons golf club's italian restaurant, quattro, nominated for two time out awards
- Skype launches its Website in Arabic to help connect families and friends just in time for the festive season


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Lollipop Chainsaw
- Platforms: PS3, X360
- Developer: Grasshopper
- Publisher: Warner
- Genre: Action, Third Person
- VN:F [1.9.22_1171]User Score: 0 votes
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Lollipop Chainsaw is the 'un-deadly' story of sweet but killer zombie-hunter Juliet Starling and her quest to uncover the root of a colossal zombie outbreak. With her wickedly awesome chainsaw in hand, Juliet slices, dices and splits her way through hordes of the undead, but soon realises the horde is only the opening act to a festival of zombie rock lords determined to kill the chainsaw-wielding cheerleader. Lollipop Chainsaw is being developed by GRASSHOPPER MANUFACTURE, led by celebrated game developer Goichi Suda (aka SUDA 51) and featuring the musical compositions of the renowned Akira Yamaoka. In addition, Hollywood director and writer James Gunn (Super, Slither, Dawn of the Dead, Tromeo and Juliet) has brought his cult humor and edgy storytelling to Lollipop Chainsaw's script
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Lollipop Chainsaw
Great like a lollypop but equally lacking depth and forgettable
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