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Dogged on disarmament, actor Michael Douglas earns Unicef award
Published on Jan 15, 2014 9:18 AM
BEVERLY HILLS, California (REUTERS) - Oscar-winning actor Michael Douglas says his main philanthropic cause - nuclear disarmament - is not exactly the kind of "touchy-feely" issue that celebrities and their fans covet, and it can be awfully frustrating when it comes to progress.
It is one, however, he has stuck with for years as a United Nations Messenger of Peace since 1998, and for that persistence he will be recognised on Tuesday night, Jan 14, 2014, with the Danny Kaye Humanitarian Peace Award from the US fund for Unicef, the UN branch for children.
"I was born in 1944, one year before the first bomb went off, and I hope in my lifetime to see the elimination of the weapons," Douglas told Reuters ahead of Unicef's Beverly Hills ball, with childhood friend Dena Kaye, the only daughter of the late comic actor and Unicef's first ambassador, by his side.
That he is being honoured with the Danny Kaye award is especially meaningful, he said, because he knew Kaye as a child, admired his impact on children and can still recite rhymes from his films. He said Kaye "did more for the United Nations and for Unicef than anyone I can think of."
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Date: 1948 ca.
Description: Small button tag on a string promoting "Republican, General Douglas MacArthur for President."
Date: date unknown
Description: Two two-sided booster tags, one featuring "Brown County Packer Booster" and the other (which is featured on the reverse of the Packer tag, and vice versa)...
Date: 1885-07-23
Description: Mourning Badge with the image of Ulysses S. Grant.
Date: 1946-02-12
Description: Identification papers of Hans E. Skott, an officer with the United Nations Relief and Rehabilitation Administration. His title was "Registered Agricultural...
Date: 1944
Description: Holiday card made out of wallpaper. Ivy and berries frame the message which reads: "With a paper shortage at Christmastime, Sort of makes one cross and sur...
Date: 1893 ca.
Description: Cover of a box produced by The Singer Manufacturing Company, which holds "Costumes of All Nations" souvenir cards, created for the 1893 World's Columbian E...
Description: The world is flat; we get aroundthis stretched credulityby going straight as an arrowand meeting ourselves in a space of time
Description: Even the slow, dry, hungry engines,diggingwhat would be the best of times,cannot help but leave behind thema restlessness unchanging as bef...
Description: Pen and ink memento of General William T. Sherman's Civil War campaign at Atlanta, Georgia, with pieces of a Union Flag attached.
Date: 1809
Description: Embroidered sampler of a map of the United States.
Description: Bring back somehow the big HelloProlong the noisiest dayThe clapping hands are stilled too soonAnd much too far away
Date: 1936 ca.
Description: Badge for the Wisconsin Beekeepers Association 58th Annual Convention at the Hotel Retlaw in Fond du Lac, Wisconsin. October 29, 30, 1936. Courtesy of Ruep...
Date: 1885
Description: Stephen M. Babcock's membership card for the League of American Wheelmen, Geneva Bicycle Club of New York for the year 1885. The card is signed by Secretar...
Date: 1877
Description: Punch paper "Home Sweet Home" sampler.
Date: 1975 ca.
Description: International Harvester Scout cabs and bodies color chart. Contains paint chips for the main exterior body color and matches this with the interior color s...
Date: 1819 date unknown
Description: A commemorative handkerchief created by a wood engraving on white cotton fabric. The scene is the Manchester Reform Meeting, in England. A crowd of demonst...
Date: 1964
Description: Inside of Coke bottle cap with a head shot of NFL All Star defensive end, #87, Willie Davis.
Date: 1882-03-19 ca.
Description: Certificate creating Post Number 25, Department of Wisconsin, of the Grand Army of the Republic.
Description: For any master line drawn fine enough or spoken welllet us call all professionals to wear the laureland deck the Halls of Fame
Description: A one-sided badge with the words "I'm From Green Bay Wis." printed on it.
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text: WE eat at Country Squire a couple times a month usually on Fridays. My husband says they have the BEST Lake Perch he has ever eaten. I have tried many other items such as shrimp, prok chops, chopped sirloin and everything us excellent. They also have an old fashioned salad bar that is quite good.


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Staff Reporter
A photography exhibition brings 25 world heritage sites in Mexico to Delhi
NEW DELHI: Instituto Cervantes is hosting a photography exhibition of the world heritage sites in Mexico at its Hanuman Road premises here.
The exhibition, which opened on Monday and is on view up to January 31, showcases photographs of 25 sites recognised by UNESCO in Mexico. They include the archaeological zone of Monte Alban (Oaxaca), the pre-Hispanic cities of Teoltihuacan (State of Mexico), Xochimilco (Mexico City), Sian Ka'an (Quintana Roo), Fortune Teller pyramid (City Uxmal), Tajin (Veracruz) and the Luis Barragan house and studio (Mexico City) among others.
The 1972 UNESCO Convention for protection of world cultural and natural heritage is aimed at preserving the creative works of human genius of "outstanding value" as well as sites of natural value, high biological diversity and natural beauty. This distinction gives Mexico a special responsibility to protect its world heritage sites for future generations.
Inaugurating the exhibition, Mexican Ambassador Jaime Nualart said UNESCO declared 29 sites in Mexico as world heritage sites. "In this exhibition we are showcasing 25 pictures of world heritage sites. Mexico is No. 3 in cities catalogued as world heritage sites in America. It is not only the responsibility of Mexico to conserve and protect the monuments, landscape and artistic beauty but of the entire humanity."
According to Instituto Cervantes director Oscar Pujol, the exhibition is aimed at showcasing the Hispaniac culture. "I hope Delhiites are able to find a connection with Indian heritage sites and Spanish archaeological heritage."
Mexico is one of the 162 States that currently adhere to the World Heritage Convention. The images were taken by independent travel photographers Ignacio Guevara, Alberto Moreno, Oscar Alvarez, Carlos Sanchez Pereyra, Claudio Contreras Koob and Rafael Doniz.


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Honda Generator EU10i How To Fix Rough Idle
What do you think about this video?
sarahmorrill: After trying a lot of SeaFoam on my eu2000i with just a little improvement,
I tried removing the pilot jet (idle jet) as shown in this video. Yes, it
was clogged. I tried several different kinds of wire and a needle and
nothing would unclog it even after soaking it in carb cleaner. I suppose I
could have used a mallet on the needle but there's the fear of making the
hole larger than it's supposed to be. So, I was getting ready to order a
new one for $18. But then I spoke to a Honda technician and he suggested I
try twisting a tiny drill bit into the hole. I went to the hardware store
and bought the smallest bit they had. Usually, they'll display a 1/16th as
the smallest but that's too big. Luckily, I found a smaller bit made by
Vermont American. The size is listed as #60 and it t cost me just $2.50.
After a couple minutes of delicate twisting, it finally made its way
through. I reinstalled it and that solved the problem.
robin saunders: thankyou very much.this vid.sorted out the problem.with my ex7.running great now.
brownskinmedallion: Worked perfectly on my Honda EU2000i, which is the larger model. Thank you very much, I do appreciate it!
Pa Bar: Cleaning the main jet didn't do the trick? Still needs choke to run well? Here's the next step… The guy at my Honda generator store told me that what I needed was a NEW main jet. Told him I made sure it was clean as a whistle. He said that over time the main jet, which is brass becomes tarnished (inside the hole) so that the orifice is just a fraction smaller than originally intended. Install a new one and Shazamm! no more choke needed. He also was adamant about the ethanol content of modern fuels raising hell with most fuel system components, said if you can get AVGAS (which has no ethanol) you'll have fewer problems. The Honda part you need is "Jet, Main (#62)" part number is 99101-ZG0-0620… cheap solution... I paid $5.14 retail. Job done.
rollin3z: Did you make a video for that? Thanks
NZVideoGuy: Fantastic!!! Thanks heaps!! :-)
strake750: I have a kiper100 generator it's running real lumpy I'm surprised it doesn't konk out do you think this remedy will work...thanks
jmsmsagrada: My eu2000i was badly clogged with aged fuel. Using "Mechanic-in-a-Bottle" to clean out the fuel tank and carburetor was helpful, along with your suggestion to remove the plastic jet for cleaning. Those treatments restored the eu2000i to like new operation in both the full power mode and the ECO mode. No more having to deal with hard starts, playing with choke settings, and loping operation. My eu2000i now operates like it did when it was brand new! Thanks again.
norman hayes: Thank you for helping me you called it right!!!!!!!! You fix my generator
sputzelein: absolutely great, thank you. I had the "loping in idle" problem with the eu20i and this video was the solution. On the eu20i you even don´t need to remove the carburetor. Now it runs smooth in idle like it should do.
darthbj: Thanks for the video! However, I'm unsure as to how to clean out the jet, you seem to be probing it with a needle at the end of the video, is that all there is to it? Cheers
John Long: thank you very much on behalf of all honda 10i generator owners for taking the time to share this knowledge.
FioletPL: One more question to you. At 0:57 you remove the fule pipe and then take out the carburetor. I made a mistake and I pulled the whole thing out first. So the fuel pipe, which comes out from another, thicker pipe, was pulled out from it by some 2-3 cm. Now I wonder if it's safe and how to repair it. I don't know where the other end goes and how much it goes into the thicker pipe. To avoid fuel spillage and fire during work.
FioletPL: You helped me a lot. Thanks.
FioletPL: I just wonder. I have a no-name snowblower and a Partner lawnmower, and none of them gets clogged because of leaving fuel in them for longer periods. I just add a fuel stabilizer into the tank. Do you think that in case of this generator it should also be enough or do I always have to drain it after use, period? I'm afraid that in this case it's not about low octanes after a period of time. Such draining after and filling before each use is quite troublesome. Is there no way to overcome this?
Honda Generator EU10i how to fix rough idle 4.9 out of 5


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I want YOU to join us in a nation-wide event the weekend of October 21st at the Merrell Institute on Long Island, New York!
The event will be two and a half days of learning how YOU can stop the bipolar left-right gridlock that has gripped our nation, learning about current issues, getting to know your fellow Reformers and learning how to participate and be effective. This event is open to ALL REFORMERS and centrists from across the country including individuals who are not party members.


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Affluent Lifestyle Guide
You might like Best Runway Models >
Kobe Bryant doesn?t appreciate how critics were calling Carmelo Anthony the Knicks? problem during Linsanity last season, and now they are treating him like a savior. ?I think last year was very tough for him because he was criticized a lot for shooting and for playing the way he likes to play,? Bryant said after scoring a game-high 31 points.


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Net Cetera: Chatting with Kids About Being Online
Federal Trade Commission, January 2014
Heads Up: Stop. Think. Connect
Federal Trade Commission, July 2013
Protecting Your Child's Privacy Online
Federal Trade Commission, July 2013
Technology, Teen Dating Violence and Abuse, and Bullying
National Institute of Justice-Sponsored, July 2013
Children's Online Privacy Protection Rule: A Six-Step Compliance Plan for Your Business
Federal Trade Commission, June 2013
Keeping Children Safe Online
U.S. Computer Emergency Readiness Team, February 2013
Staying Safe on Social Network Sites
U.S. Computer Emergency Readiness Team, February 2013
Teen Dating Abuse and Harassment in the Digital World: Implications for Prevention and Intervention
National Institute of Justice-Sponsored, Office of Juvenile Justice and Delinquency Prevention-Sponsored, February 2013
Evaluation of Internet Child Safety Materials Used by ICAC Task Forces in School and Community Settings (Final Report)
National Institute of Justice-Sponsored, December 2012
Child Pornography on the Internet
Office of Community Oriented Policing Services, May 2012
Kids and Virtual Worlds
Federal Trade Commission, September 2011
Sexting: A Typology
Office of Juvenile Justice and Delinquency Prevention-Sponsored, March 2011
National Strategy for Child Exploitation Prevention and Interdiction: A Report to Congress
U.S. Department of Justice, August 2010
Effects of Federal Legislation on the Commercial Sexual Exploitation of Children
Office of Juvenile Justice and Delinquency Prevention, July 2010
Youth Safety on a Living Internet: Report of the Online Safety and Technology Working Group
Online Safety and Technology Working Group, June 2010
Much Ado About Sexting
National Institute of Justice-Sponsored, June 2010
Internet Crimes Against Children: A Matrix and Summary of Major Federal and Select State Case Law
National Institute of Justice-Sponsored, November 2009
Internet Crimes Against Children: A Matrix of Federal and Select State Laws
National Institute of Justice-Sponsored, November 2009
Internet Crimes Against Children: An Annotated Bibliography of Major Studies
National Institute of Justice-Sponsored, November 2009
Virtual Worlds and Kids: Mapping the Risks
Federal Trade Commission, January 2009
Keeping Kids Safer on the Internet: Tips for Parents and Guardians
English or Spanish
Office of Juvenile Justice and Delinquency Prevention-Sponsored, 2009
Enhancing Child Safety and Online Technologies: Final Report of the Internet Safety Technical Task Force to the Multi-State Working Group on Social Networking of State Attorneys General of the United States
Berkman Center for Internet & Society at Harvard University, December 2008
Electronic Media and Youth Violence: A CDC Issue Brief for Educators and Caregivers
Centers for Disease Control and Prevention, 2008
Implementing the Children's Online Privacy Protection Act: A Report to Congress
Federal Trade Commission, February 2007
Statement of Assistant Attorney General Alice S. Fisher before the Committee on Energy and Commerce Subcommittee on Oversight and Investigations Concerning Sexual Exploitation of Children over the Internet: What Parents, Kids and Congress Need to Know About Child Predators
U.S. Department of Justice, May 2006
Keeping Kids Safe Online: Advice from an FBI Cyber Agent
Federal Bureau of Investigation, April 2006
Social Networking Sites: Online Friendships Can Mean Offline Peril
Federal Bureau of Investigation, April 2006
Child Pornography: Patterns From NIBRS
Office of Juvenile Justice and Delinquency Prevention, December 2004
Protecting Children in Cyberspace: The ICAC Task Force Program
Office of Juvenile Justice and Delinquency Prevention, January 2002
Internet Crimes Against Children
Office for Victims of Crime, May 2001
A Parent's Guide to Internet Safety
Federal Bureau of Investigation, Publication Date Unknown
Commercial Sexual Exploitation of Children (CSEC)
The CSEC page highlights programs and efforts supported by the Office of Juvenile Justice and Delinquency Prevention to address the commercial exploitation of children and assist its victims.
Crimes Against Children Research Center
Funded in part by the Office of Juvenile Justice and Delinquency Prevention, the Crimes against Children Research Center serves to combat crimes against children by providing research and statistics to the public, policy makers, law enforcement, and other child welfare personnel.
Electronic Aggression (Podcast)
The Centers for Disease Control and Prevention's Electronic Aggression Podcast focuses on how new forms of electronic media (blogs, chat rooms, text messaging, and the Internet) are providing new arenas for youth violence to occur.
Federal Bureau of Investigation (FBI): Cyber Crime
The FBI works to prevent criminals, sexual predators, and others intent on malicious destruction from using the Internet and online services to steal from, defraud, and otherwise victimize citizens, businesses, and communities.
Federal Bureau of Investigation (FBI): Violent Crimes Against Children
The mission of the Violent Crimes Against Children program is: to decrease the vulnerability of children to sexual exploitation; to develop a nationwide capacity to provide a rapid, effective, and measured investigative response to crimes against children; and to enhance the capabilities of state and local law enforcement investigators through programs, investigative assistance, and task force operations.
Federal Trade Commission (FTC): Kids' Online Safety
This section of the Federal Trade Commission (FTC) site provides online privacy guidelines and resources for kids, parents, and educators.
In partnership with government and private citizens, INOBTR ("I Know Better") promotes awareness and educates children, parents and teachers to reduce the chance of children becoming victims of Internet crimes.
Internet Crimes Against Children (ICAC) Task Force Program
Funded by the Office of Juvenile Justice and Delinquency Prevention, the ICAC Task Force Program was created to help law enforcement agencies enhance their investigative response to offenders who use the Internet, online communication systems, or other computer technology to sexually exploit children.
National Center for Missing and Exploited Children (NCMEC)
The NCMEC mission is to help prevent child abduction and sexual exploitation; help find missing children; and assist victims of child abduction and sexual exploitation, their families, and the professionals who serve them.
National Institute of Justice (NIJ)
NIJ is the research, development and evaluation agency of the U.S. Department of Justice. Following are NIJ multimedia resources that focus on the topic of online safety:
Office of Juvenile Justice and Delinquency Prevention (OJJDP)
OJJDP provides national leadership, coordination, and resources to prevent and respond to juvenile delinquency and victimization.
Project iGuardian
Project iGuardian is a national cyber safety campaign spearheaded by U.S. Immigration and Customs Enforcement's Homeland Security Investigations in partnership with the National Center for Missing & Exploited Children. As part of Project iGuardian, schools and youth groups can request presentations on how to avoid falling victim to online sexual predators.
Project Safe Childhood (PSC)
This U.S. Department of Justice initiative combats the use of computers for the purposes of sexual exploitation crimes against children. It aims to investigate and prosecute offenders, as well as protect and assist victimized children.
U.S. Department of Justice Child Exploitation and Obscenity Section (CEOS)
The mission of the CEOS is to protect the welfare of America's children and communities by enforcing federal criminal statutes relating to the exploitation of children and obscenity.
Links from the NCJRS Web site to non-Federal sites do not constitute an endorsement by NCJRS or its sponsors. NCJRS is not responsible for the content or privacy policy of any off-site pages that are referenced, nor does NCJRS guarantee the accuracy, completeness, timeliness, or correct sequencing of information. NCJRS is also not responsible for the use of, or results obtained from the use of, the information. It is the responsibility of the user to evaluate the content and usefulness of information obtained from non-Federal sites.


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If there's ever a tamal shortage in McAllen, it might be the Rio Grande Valley Vipers' fault. The Houston Rockets' minor league affiliate has always made a fair amount of three-point shots, so before the current season, local institution Delia's Tamales sponsored a promotion: any time the Vipers hit a dozen treys at home, fans could bring their ticket stub into the restaurant for a buy-a-dozen, get-a-half-dozen-free deal, good for 24 hours. Problem is, the Vipers' shooters did that fourteen out of fourteen times, often without waiting for the second half (the streak finally ended February 8 against the Austin Toros). Delia's loved the crowds—and all the scoring—but still, they couldn't help but gripe to team officials that their free tamal obligation was significantly higher than projected.
Delia's knew that the Vipers were good—they were, after all, the defending NBA Developmental League champions—but nobody accounted for the particularly three-point-obsessed philosophy of first-year Vipers coach Nevada Smith, who took over last October. Smith stepped into a successful franchise. Since partnering with the Rockets in 2009, the Vipers have won two championships (and they went to the finals in 2011); two of the team's former coaches have gone on to be assistants in the NBA (Chris Finch with the Rockets and Nick Nurse with Toronto). Current Rockets starters Patrick Beverley and Terrence Jones played for the Vipers, as did Aaron Brooks, Greg Smith, and Donatas Motiejunas. Even more important, the Vipers serve as lab rats for the Rockets in terms of strategy, statistical analysis, and sheer trial and error, and Smith is the mad scientist.
"There's certain basketball factors that you can't evaluate at the NBA level, because it's going to cost you wins and losses," says Gersson Rosas, the Rockets' co-head of scouting and player personnel, who also was the Vipers' general manager from 2009 to 2013. "But at the D-League level, you can experiment, you can try things, you can see the results and then apply it [in the NBA]."
The 33-year-old Smith, a former Division 3 college coach, has taken the experiment to a new level, favoring an especially high-motor, three-point-enamored offense in a league that is already higher-scoring than the NBA. On December 2, a mere four games into Smith's tenure as head coach, the Vipers made 24 three-pointers, breaking a D-League record that had held up for five seasons. The next night, they hit 23. Vipers all-star guard Troy Daniels shoots—and makes—so many threes he broke the D-League's single-season record in just 27 games (a full season is 50). The Vipers' average 45.1 three-point attempts a game; the Rockets lead the NBA in average three-point attempts with 25.8. In December, Zach Lowe of the ESPN website Grantland anointed the Vipers "the most innovative pro basketball team you've never seen."
The Vipers current season shot chart. Note the number of shots taken outside of the three-point line.
In some ways, Smith's strategy is simple, and almost settled law around the NBA: it's best to either take shots that are worth more (three-pointers) or take shots that are easiest to make (dunks or layups). In December, Beverley, the Rockets' starting point guard, told ESPN.com's Ethan Sherwood Strauss, "The only thing we're shooting in practice are layups and threes." Of course, taking—and making—a lot of shots is the point, but the Vipers are able to put the ball in the air so often because they're playing fast and rebounding well. Smith takes this approach to the extreme in part because he can, but more likely because his boss, Rockets general manager Daryl Morey, wants him to.
Morey founded the MIT Sloan Sports Analytics Conference, a convention where people discuss the rising importance of sports analytics, and he was the first general manager of an NBA team to be hired because of his Moneyball-style approach to the draft and scouting. And he's clearly pleased with the way the Rockets' D-league team performs. Earlier this month, Morey tweeted that the Vipers had the most efficient offense (a statistic measured by points scored per 100 possessions) of any team at any level of pro basketball since 2000. The D-League bills itself as the NBA's "research and development laboratory," a role the Rockets encourage as both sober intellectuals and unhinged experimenters.
"The Rockets take the Vipers and the D-League really, really seriously," says Gianluca Pascucci, who is both the Vipers general manager and one of the heads of Houston's scouting and player personnel department. The other is Rosas, who gave way to Pascucci as the Vipers GM when he left Houston for an ill-fated stint with the Dallas Mavericks. "A lot of the things we did there in RGV in terms of strategy and philosophy have filtered up here to Houston," says Rosas.
Now it's Smith's turn. "We try some different stuff, see if it works," he says. "We're doing some things right now that are a little crazy, but it's fun. It's still basketball. We still do basic basketball things, but we just look for other end results."
The Vipers may be transforming certain aspects of basketball, but they're still a minor league team, and minor league teams do things like get lost on the way to practice during road trips. The day before a recent game against the Austin Toros, Smith glanced at the itinerary and told the local shuttle driver to proceed from the Candlewood Suites to the Cedar Park Center, the suburban arena home of the Toros and the Texas Stars. In fact, practice was at the Cedar Park Recreation Center, a public gym tucked in a D. R. Horton planned community, with two courts underneath a running track. "NO DUNKING," instructed a sign at both ends of the court. "No hanging on rims or nets."
Practice is basically an assembly line of three-point shots, with five guys shooting and five guys rebounding at any given time, followed by a scrimmage. Smith presides over the team in red-and-white Adidas sneakers, a gray "RIO GRANDE BASKETBALL" T-shirt, and red shorts.


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DMV to Internet-less New Yorkers: Get in Line
By Jared Chausow
By Katie Toth
By Elizabeth Flock
City Hid Facts From Feds About Rikers
By Albert Samaha
Flood Wall Street Gets Pepper Sprayed and Arrested
By Anna Merlan
By Jon Campbell
Report Sheds Light on Anti-Muslim Bias
By Jon Campbell
Rikers Island Lawsuits Over Diabetic Care
By Albert Samaha
Let's focus only on the ungloved facts and realities, even if former child stars and their accusers don't always remember to do so. Let's not leap on every leaked allegation as gospel truth to cherish and abuse. So there may have been both adult and childrens' fingerprints on the porn mags? Well, I'm sure Jacko and the kids ("Blowhole" and "Doo Doo Head") were just innocently using the rags as coasters for the Jesus juice, OK? (Mighty white stuff of him.) With generous observations like that I probably shouldn't be a juror in this casejust a judge.
Sponsor Content


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Albergo Villa Marta invites everyone to enjoy a delicious Easter lunch at their restourant Botton D'Oro. We are waiting you with a delicate seafood menù in an elegant and refined contest.
See the menù dowloading the link below.
Easter Lunch Menù.
Happy Easter!
The staff
The event of the summer. Some fabulous concerts will fill the squares of Lucca in July. Once again there will be international names. Check the programme below. ( New dates will be added soon):
July 5th 2015 JOHN LEGEND, Piazza Napoleone 9:00 p.m
July 8th 2015 PAOLO NUTINI, Piazza Napoleone 9:00 p.m
July 9th 2015 THE SCRIPT, Piazza Napoleone 9:30 p.m
July 10th 2015 BILLY IDOL, Piazza Napoleone 9:30 p.m
July 11th 2015 ELTON JOHN, Piazza Napoleone 9:30 p.m
July 22nd 2015 MARK KNOPFLER, Piazza Napoleone 9:30 p.m
July 23rd 2015 ROBBIE WILLIAMS, Piazza Napoleone 9:30 p.m
July 24th 2015 FEDEZ-JAX, Piazza Napoleone 9:00 p.m
July 26th 2015 LENNY KRAVITZ, Piazza Napoleone 9:30 p.m
For further information and reservation visit the web site www.summer-festival.com
The 2015 Camelia exhibition dates are officially out. For the 26th year it is taking place in Pieve di Compito and Sant' Andrea Di compito, during the second, third and the last week end of March.
Moreover, on association with Verdemura (an exhibition/market that will be held on the walls of Lucca on 27th, 28th, 29th of March) there will be discounts for those who want to buy tickets in advance for both manifestations and free shuttles to make your transfer easier.
Lucca and the part of the land where these cities are located is favourable for the growth of these flowers and they are the symbols of the territory. An important peculiarity of the ground is the acidity that has facilitated the cultivation since XVIII century.
We are waiting for you and we will be delighted to show you the beauty of our country.
From 27th to 29th of March, Lucca will once again be the capital of gardening, thanks to Verdemura: flower exhibition/ market organized by the Opera delle Mura of Lucca.
Verdemura opens the long season of Italian exhibitions of gardening. Lucca celebrates the arrival of spring inviting you all to visit one of the greenest places of Tuscany: the wall park, a unique place all over the world.
The wall park, 96 hectares wide, is free from cars and represent a master piece among the European public green zones.
Its ring form and its 4.2 km walk with trees surround the city centre.
Verdemura takes place in the bastion of San Martino, next to Santa Maria gate, where there are 150 stands: nursery men, bulbs, shrubs, tolls and furniture for gardening and vegetable gardens. A special place rich of panoramas on the city and on the surrounding areas.
For further information check the web site www.verdemura.it


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Car News26 May 2015
Here's the Mahindra XUV500 faceliftTopGear.com
M&M's given its 'cheetah' a makeover to keep things fresh
First Drive
First drive: Lamborghini Aventador SV
The quite mad V12 supercar gets more power, more wing and more mad
Car News
Yellow fever: it's the BMW 3.0 CSL Hommage
Remember BMW's big-winged 'Batmobile' of the early Seventies? It's back. Jason Barlow reports
Bike News
Mahindra readying Peugeot scooters for India; Mojo launch by September
M&M's two-wheeler division's working to bring a handful of two-wheeled Pugs (as well as a three-wheeled one) to India soonish. And, the Mojo is almost ready. We have all the dope
Car News
Meet the lovely Zagato Mostro
Custom-built. Retro curves. Italian V8. So much want. Meet Zagato's tribute to 1950s Maserati
Car News
Listen to a 770bhp Quattro monster
Video: replica of Audi's rally icon with ludicrous power sounds utterly, utterly insane
Car News
Meet the Fiat Aegea
The Linea's successor has been unveiled in Istanbul
Car News
Don't shoot! It's the Mercedes S-Guard
Bullet proof, grenade proof S-Class is now available in India
First Drive
First drive: Porsche 911 GT3 RS
Is the 492bhp, track-ready 911 the best of the bunch?
Car News
This is the updated Volkswagen Vento
The German sedan gets another midlife makeover


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PUNXSUTAWNEY ã It's a spicy, hot pizza ã and we do mean hot ã when World Pizza Champion (WPC) Patt Miller returns to Punxsutawney to flip his flaming pizzas as part of this weekend's Groundhog Day festivities.
Rob McCoy, director of the Punxsutawney Area Community Center (PACC), said Miller will headline several performances in the Jackson Theater and in Barclay Square throughout the holiday weekend.
McCoy said Miller made his mark in Punxsutawney during Groundhog Festival week in 2010, as he performed on South Gilpin Street and in the Jackson Theater in addition to a local competition held involving staff members of the Punxsutawney Spirit.
During the 2013 Groundhog Day festivities, Miller and his colleagues will entertain crowds via their pizza antics with official show times at 9 p.m. Friday at PACC and 9 a.m. Saturday in Barclay Square to the right of the bandstand, McCoy said, adding that between shows they will be "tossing" around town.
McCoy said the acrobatic routine is set to music.
"This routine incorporates tricks, like across the shoulders, through the legs, two at a time and floor movements," McCoy.
He added that when Miller performs his flaming pizza routine, things really start to heat up, especially when he performs it on stage at the Jackson Theater.
He said the routine will be followed by a demonstration that brings audience members on stage to try and learn how to toss a pizza.
"It works out well on Friday, because we will be showing ãGroundhog Dayã the movie at 5 and 11 p.m., and there will be people in and out of the center for the craft show,ã he said.
McCoy said a highlight of WPCs visit to Punxsutawney will be two special performances that will occur at Gobblerãs Knob with Inner Circle member Dave Gigliotti, Thunder Conductor.
ãI was very excited when I heard about the WPC coming to Punxsutawney to join us for the Groundhog Day celebration," Gigliotti said.
ãThey are very entertaining and are sure to put on a great show,ã said Katie Donald, executive director of the Punxsutawney Groundhog Club Inner Circle.
McCoy said the World Pizza Champions have appeared on major networks across the globe.
Miller himself has appeared on ãAmericaãs Got Talent,ã ãWorld Pizza Games ã Las Vegas,ã ãJimmy Kimmel Live,ã ãGood Morning America,ã ãThe Today Showã and Telemundo.
In an interview, Miller said he has been pizza tossing competitively since 2005 and now owns three pizzerias in Columbus, Ohio.
He said he got his start when he was 15 years old at Dewey's Pizza in Cincinnati, Ohio, where he first witnessed pizza-spinning.
"I was the youngest employee in the kitchen to toss, and soon became the best at Dewey's Pizza," Miller said, adding that, since 2005, he's competed in competitions around the world, placing more than 10 times in different categories, including acrobatics, largest stretch, fastest pizza maker and culinary.
McCoy also said the group will be available for photo opportunities after the shows.
The World Pizza Champions was founded by Tony Gemignani, nine-time World Pizza Champion.
The Champions form an affiliation to promote their restaurants and skills and, most importantly, to "respect the craft."
You can read about The World Pizza Champions at www.worldpizzachampions.com.


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|Half Baths
|Property type
|Minimum Stay
|3 - 7 nights
A perfect romantic setting for your honeymoon or anniversary! Be outrageously spoiled by the wonderful amenities of the romantic Joy Chalet set at the edge of a 33 acre woodlands conveniently located at the south edge of Asheville. You'll be pleased by the elegant comfortable furnishings, luxury king bed with sumptuous bedding, soft towels, hot tub for 2 on a private covered screened back porch, Jacuzzi bath tub, awesome massage chair, a fully-equipped kitchen with quality cookware, outdoor gas grill, living room with gas log river stone fireplace on a 20' cathedral ceiling, movie library, WiFi & central heat & air! Lovingly furnished, the chalet is both beautiful & comfortable. Follow the woodlands path to a creek with a swing suspended from a tree.
INDULGE! You deserve to be spoiled at my vacation home! I am a caring local owner and answer all inquiries personally. I am available anytime to see to your needs. I make sure the home is exceptionally clean, well maintained & the hot tub sparkling with fresh water.
SEE MY WEBSITE LINK BELOW (or email me) FOR 40+ PHOTOS & ALL 10 OF MY ASHEVILLE & HENDERSONVILLE VACATION RENTAL HOMES.
The luxurious, very comfortable couches and rich marble tables are quietly elegant and a perfect nest to watch your flat screen TV with simple-to-use built-in DVD. Choose from over 100 movies in our video library or watch cable TV. Better yet, it's the ideal spot to just peacefully sit and unwind in front of the fire in the river stone gas log fireplace.
Your romantic upstairs king bedroom suite features a magnificent tapestry over a sumptuous Simmons king bed, 400 count cotton sheets, butter-soft blanket and elegant comforter. Lay in luxury while you watch your flat screen TV with a simple-to-use built-in DVD/VCR. A handsome dresser, chest of drawers and walk-in closet offer plenty of space for your clothes. And, best of all, an amazing Human Touch Technology Massage Chair will send you to heaven! It's our favorite ultimate pleasure. A tasteful bathroom with a Jacuzzi bathtub/shower and sumptuously thick cotton towels complete the master suite. A perfect honeymoon nest!
Your delightful eat-in kitchen is fully equipped with all new everything! You have full size new appliances including stainless refrigerator with French doors & bottom freezer drawer, ceramic glass cook top with self-cleaning oven, dishwasher, microwave, and disposal. Enhance your meals by serving them on our festive hand painted dinnerware, heavy glasses and quality silverware. You'll find sharp knives, a multitude of pots, pans, bake dishes, cookie sheets, cake pans, pizza pan, muffin pans, hand mixer, toaster, blender, waffle iron, coffeemaker and even a coffee grinder for your freshly brewed coffee. You'll find a selection of spices and a few other goodies as well. Just off the kitchen is a full size washer and dryer as well as a pretty powder room half bath.
Just out the kitchen door is the wonderful screened, covered porch. Relax there in privacy in your 2-person spa hot tub ( privacy screens) or sip on a morning cup of coffee while you sit in the wicker chairs to view the woodlands back yard.
For the fun of it, there is a 1948 Scrabble board, a 1961 Monopoly game, a 1974 Easy Money game plus games such as chess, checkers, playing cards, Yahtzee, etc. In addition, there is a small selection of enjoyable paperback novels. With all the special touches, Joy Chalet feels like a warm, inviting home rather than a vacation rental house. Central air conditioning makes summers cool although seldom needed in these Blue Ridge Mountains.
I am a local owner who takes exquisite care of my homes and am available anytime to see to your needs. I make sure the home is exceptionally clean, well maintained & the hot tub sparkling with fresh water. SEE MY WEBSITE LINK BELOW (or email me) FOR 40+ PHOTOS & ALL 10 OF MY ASHEVILLE & HENDERSONVILLE VACATION RENTAL HOMES.
I am Stephanie Joy Johnson. My passion is creating beauty in real estate….remodeling and restoring homes, landscape design, interior home décor and, best of all, making guests feel pampered when they stay at my personally owned luxury vacation homes in the gorgeous mountains of Western North Carolina. I devote myself full-time to taking care of my homes & guests. YOU are my full-time business! My business is called Asheville Vacation Homes.
I began this business in 2004 and delight in finding beautiful locations and gorgeous homes for vacation rental settings. I am always searching for interesting furnishings (shopping!) to add to the delightful decor for my guests.
During your stay, you also might meet my awesome property manager and "fix-it man," David. He can take care of any maintenance or property issues should they arise. He and I are both available 7-days-a-week to make sure your stay is the best ever!
Email me for my web address to see all 10 of my vacation homes. Take a virtual tour at AshevilleVacationHomes.
INDULGE! You deserve to be spoiled at my vacation home! I am a caring local owner and answer all inquiries personally.
Stephanie Joy Johnson purchased this chalet in 2004
I am passionate about living in these awesome Blue Ridge Mountains of Western North Carolina and adore sharing my vacation rental homes with guests who come to experience our area's mountains & towns. I take exquisite care of my properties and am available anytime to see to your needs. I make sure each home is exceptionally clean, meticulously well-maintained and the hot tub sparkling with fresh water.
I have lived in Asheville, North Carolina for many years and find great joy in discovering more and more reasons why this is the BEST PLACE IN THE WORLD TO LIVE! Asheville is consistently in the "Top 10 Places To Live" according to almost any criterion published! It's a diverse multi-cultural blend of mountain folk and cosmopolitan society set in a dramatically beautiful mountain setting. It is my heart-felt desire to provide gorgeous welcoming homes in spectacular settings and to share this town with you!
With all the special touches, I promise you that my vacation rental homes will feel as though you are staying at a friend's warm inviting home rather than a 'vacation rental house.' You'll appreciate the tasteful decor and thoughtful care my homes reflect. Each home has been lovingly remodeled, elegantly furnished, beautifully decorated and thoughtfully accessorized with special amenities to pamper you including massage chairs, hot tubs, high speed wireless Internet, king beds with sumptuous bedding, HDTV's & DVD's, movie libraries, quality well-equipped kitchens, fireplaces, central heat & air conditioning, washers & dryers and much more!
Unique to my homes are all the amenities offered for babies and children. There are cribs, pack-n-plays, strollers, high chairs, baby bath tubs, stuffed animals & blankies. Older children love to play on the outdoor playgrounds with forts, slides, swings, climbing walls, etc. plus games, books, toys, kids DVD movies and more. Kids of all ages love to roast marshmallow at the firepits.
My homes are easily accessed, right in-town, close to grocery stores, restaurants and shopping. No winding mountain roads to get lost in or long drives to town. The homes are in peaceful, lush vacation spots where you can relax and feel at home.
Rather than dealing with a third party management company with limited business hours & knowledge of a home, you can deal directly with me, the owner. I am available to you 7 days-a-week, anytime between 9 AM and 7 PM and after hours for emergencies. I know my properties intimately because I have personally had them restored, remodeled, furnished and equipped. YOU are my full time business! Because I live locally, I am available whenever you call.
Email me for my web address to see all 10 of my vacation homes. Take a virtual tour at AshevilleVacationHomes.
My husband and I enjoyed staying at the "Joy" Chalet so much. We took everything we thought we would need. Turns out all we need was our clothes. Everything we could have dreamed of needing was in the chalet. The attention to detail, from plastic wrap to the hair dryer was provided, it was absolutely amazing. The chalet is so beautiful. We appreciated the brochures of all the places to eat, the activities(and there is a lot to do) and maps. We will most definitely be back there. Stephanie is absolutely the nicest lady in ashville. She is very attentive to all your needs. So glad we chose ashville and the "Joy" Chalet.
This was a perfect location to visit both the city attractions and the nature attractions. Very quiet and relaxing. The house is very clean and well kept. Stephanie checked on us to be sure her property met our expectations. We will be staying here again in our future trips to Asheville area.
From the moment I first spoke to Stephanie until we locked the door to leave, we had 5 star service! Stephanie was so helpful in ensuring my husband and I rented the property that was best for our needs. She kept in touch and offered excellent information on weather, shopping, restaurants and places of interest. She was very prompt in responding to e-mails and answered every question to our satisfaction. Joy Chalet was perfect. Everything we needed was available, furnishings were beautiful, comfortable and clean. This is the perfect romantic get away for a couple. We felt secluded even though the chalet is located in a neighborhood. It was very quiet and we never heard traffic or neighbors. The location is perfect and we never drove more than 45 minutes to any activity. Shopping is convenient and restaurants are plentiful and wonderful. The kitchen has every appliance and gadget for those who want to eat at home. Our stay was perfect in every way and we will definitely plan another trip -- if not to the chalet, at least to another of Stephanie's properties. She is the perfect hostess!
My wife and I stayed here during our vacation in Asheville. The chalet was convenient off of I26 and in a quiet neighborhood. Everything we needed to begin our stay was already provided! The hot tub and massage chair were VERY nice touches especially after a day of hiking around the surrounding area. We truly enjoyed our stay in the chalet and look forward to coming back in the near future!!
Joy Chalet is just perfect. Stephanie has thought of everything you might need. There is even a stand in the living room with brochures for most of the things to see and do! The hot tub was great after a hike thru Chimney Rock. I highly recommend Joy Chalet, and will be back.
We would recommend staying a "Joy Chalet". The house is well-maintained, clean, and furnished very well. The location was perfect for us. We would stay there again and recommend to anyone wanting to visit the area.
Attention to detail and amenities were above and beyond. Property was very clean and well maintained. Owner provided excellent customer service prior to our stay and follow-up after. We would definitely recommend the Joy Chalet and hope to return in the future.
There's skiing, hiking, white water rafting, miniature golf, fishing, wildlife viewing, rock climbing, you name it! Check out the new Fun Depot for a wealth of indoor fun. When George Vanderbilt had the entire world to select a site for his home in the 1890's, he choose Asheville to built his 250 room French Chateau. Famous for being the largest private residence in the United States, you can spend a full day wandering through the mansion, its grounds, greenhouses, winery, restaurants and shops. Just outside the gates of the Biltmore House is Biltmore Village. These quaint buildings and streets have enchanting shops and restaurants to delight you. Our favorite is The New Morning Gallery/Bellagio, the largest handcrafted gallery in the Eastern United States.
Guests may purchase DISCOUNTED BILTMORE ESTATE TICKETS GOOD FOR FOR 2 CONSECUTIVE DAYS WITH FREE WINE TASTING TICKET for less than the price of a one day gate ticket!
Golf: Asheville & Hendersonville are a golfer's paradise where the strikingly beautiful scenic settings provide a lush backdrop to your golf experience! These are a few of the public courses near my luxury vacation rental homes:
The upscale BROADMOOR GOLF LINKS located in the lush French Broad River Basin is a certified Audubon Society award winning 18-hole Par 72, 7000 yards golf course known for its bent grass greens & practice facility. You will encounter ponds, streams, views & abundant wildlife.
The HIGH VISTA GOLF COURSE is a scenic mountain valley 6935 yards, 18-hole championship golf course, with spectacular 360 degree views & variety of challenging terrain! Although in a private gated community, this lush course is open to the public.
The ORCHARD TRACE GOLF CULB is an 18 hole par-3 course w/2,139 yards of golf from the longest tee. It has a course rating of 54 & a slope rating of 113. It's perfect for a quick 18 hole game & reasonable green fees. Night golf is a great treat!
The CUMMNINS COVE GOLF is an 18 hole par 71 course w/long-range vistas of the Blue Ridge Mountains at this 3,000' elevation. Fairways are lined w/trees, lakes, streams, waterfalls & spectacular mountain views! From the longest tee, there are 6,415 yards of golf. The course rating is 70.1 & a slope rating of 129 on Bermuda grass.
The SOUTHERN TEE Course is a fun 18 hole, par 3 w/wide fairways. The course rating is 70.0 with a slope rating of 113 with 2573 yards of golfing
|Rate Period
|Weekend Night
May 22 2015 - Aug 31 2015
6 night minimum stay
Sep 1 2015 - Sep 30 2015
5 night minimum stay
Oct 1 2015 - Oct 31 2015
5 night minimum stay
Nov 1 2015 - Nov 19 2015
3 night minimum stay
Nov 20 2015 - Nov 30 2015
7 night minimum stay
Dec 1 2015 - Dec 17 2015
3 night minimum stay
Dec 18 2015 - Jan 4 2016
7 night minimum stay
Jan 5 2016 - Mar 18 2016
3 night minimum stay
Mar 19 2016 - Apr 9 2016
6 night minimum stay
Apr 10 2016 - May 13 2016
3 night minimum stay
May 14 2016 - Aug 31 2016
6 night minimum stay
|$89.00 + Tax
|Pet Fee
|$75.00 + Tax
|Tax Rate
Scroll to bottom of page to the last item in under "Amenities" for link "Owner's Website" with 40+ PHOTOS OF THIS HOME & ALL 10 OF MY ASHEVILLE & HENDERSONVILLE VACATION HOMES. I am a local owner who takes exquisite care of my homes & YOU! Virtual tour at AshevilleVacationHomes.
NOTE: Due to safety issues, we do not accept online payments. Please call to make your reservation to be spoiled!
VISA, MASTER CARD, DISCOVER accepted
HOLIDAYS = 6 night minimum = $1043 (Easter/Spring Break, Thanksgiving, Christmas, New Years);
PET RENT $15/night or $75/week. Dogs allowed w/prior approval & agreement to Pet Policy;
USAGE FEE = $69 (includes Cleaning, Hot Tub, Utilities, Management Fee)
Payment is usually accepted in the quoted currency (USD) unless the currency and the amount is specifically agreed in advance with the owner / advertiser.
Learn more about this vacation rental at the manager's website:


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Day 12
... we were up here i said goodbye to the three local dogs. We'd nicknamed one Smiley dog as it appeared to constantly be grinning, and when you gave it a fuss it'd get so excited it would wet itself.
Having skipped breakfast in place of coffee, we returned to Afros in Acharavi. We had a massive brunch of seafood: calamari, whitebait, tuna fritters etc. and then said our farewells to Costas and Chris. I'm sure we will see them again.
After fare-welling ...
Day 11
... was only silence. We wouldn't be going round for dinner any time soon.
My parents went out to IKEA to look at white ware so I decided to stay home and look into Istanbul. *************.
Later that afternon we checked in on the house. The tiles downstairs have been laid and the place is really starting to come together. I'm jealous that by the time my sisters visits in July it will probably be finished.
We left ...
Day 10
... flight to Istanbul on Thursday !
We decided to go and explore Corfu Castle, the older of two fortresses in the town. The fortress was huge, and had been in use for centuries. The British had built barracks here, and also a church in neo-classical style.We climed up to the light house on the top and looked out across Corfu town and the Mediterranean below. Sitting on the castle walls we watched ...
Day 9
... case someone slipped and sent him rolling down the cobblestones.
We watched the bands march through the town, finally congregating in front the Lindon cafes. Here they stood in the rain and played in turn, then marched back into the city. The whole occasion was watched over by a large crowd of Greeks, both from Corfu and the mainland, who braved the rain and cheered the bands. It was definitely worth getting out of bed for. ...
Day 7
... the windmill and had one those awkward encounters you get holiday, with a German couple that we just kept running into. They're weren't our friends, but it would have been weird not to say hi. If we run into them again we may even have to start a conversation ! God forbid, thats every English person's nightmare. Ha !
Surviving the awkwardness, we carried on around the coast towards Mon Repos, the old ...


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A service breakdown
On Feb. 7, 2013, around 1 to 4:30 in the afternoon, the Department of the Interior and Local Government-National Capital Region experienced a breakdown in our telco service. The problem reoccurred on Feb. 8, from 9 until 10:40 in the morning.
This is not the first time Globe Telecom Inc. failed to deliver the service it is obliged to provide its consumers. Since November 2012, we have experienced three service breakdowns.
As a government agency, we are expected to deliver efficient and reliable service to our public. Communication is vital to our work and interruptions of this kind in our communication system keep us from doing our work effectively.
With this letter, I hope to call the attention of Globe Telecom and help it improve its service. If Globe Telecom can be reckless with its business with the government, how much more with an ordinary citizen who does not command as much authority?
Our department believes that communication is a serious business and we trust that the Inquirer shares the same conviction for we are not just serving the people; we are banking on their trust.
—RENATO L. BRION, Ceso 3,
regional director,
Department of the Interior and Local Government
National Capital Region
Norbertina Bldg., 2 East Ave. cor Edsa
Barangay Pinyahan, Quezon City
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True 138 SS Chevelle, 396ci V8 Automatic, 12 Bolt Posi Coming Soon! Call Tom 7 Days a Week! 248-974-9513... More
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Vegan Cheese Ball Spread
1 (6 ounce) package vegan blue cheese 4 ounces vegan cream cheese 1 teaspoon white onion, finely chopped 1 teaspoon vegan Worcestershire sauce 1/2 cup walnuts, chopped 2 tablespoons fresh Italian parsley, chopped
1. Combine the blue cheese, cream cheese, onion, and Worcestershire sauce in a medium bowl. Mix well. 2. Refrigerate for at least 1 hour, up to 24 hours. After chilling time, mix the walnuts and parsley. 3. Form the cheese mixture into a large ball. Roll around in parsley and walnuts. Serve with crackers. Source of recipe: I modified the ingredients of this recipe from the cookbook "Dishes Men Like". For more information, please see my blog here: http://veganmiss.blogspot.com/2011/03/dishes-men-like-mystery-cheese-bal...
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Tablet. Hotels for Global Nomads
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The role of the anatomy of the sigmoid colon in developing sigmoid volvulus: a cross-sectional study
- Olusegun Isaac Alatise,
- Olusegun Ojo,
- Polycarp Nwoha,
- Ganiyat Omoniyi-Esan,
- Abidemi Omonisi
- … show all 5 hide
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The aim of this study was to determine the length of the sigmoid colon and sigmoid mesocolon in living subjects and fresh cadavers.
The subjects for the study were consecutive 50 living subjects undergoing abdominal surgeries via midline incision and 50 fresh cadavers undergoing a medicolegal postmortem at Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, Nigeria.
The study showed that the mean length of the sigmoid colon in living subjects was 48.9 ± 1.3 cm (range 30.5–65 cm) while the mean length of the sigmoid colon in cadaver subjects was 50.1 ± 1.6 cm (range 34.5–67.8 cm) and this was not statistically significantly different. Two patterns of the shape of the sigmoid loop were identified: dolichomesocolic and brachymesocolic pattern. In about 80 % of subjects in both groups, dolichomesocolic-type was seen. The gender analysis showed that males had statistically significant longer sigmoid colon (P = 0.040). The dimension of sigmoid colon significantly increased with age of the patients in cadaver subjects and in both sexes (P = 0.001).
The study concluded that the lengths of sigmoid colon are not different in living and cadaver subjects but are relatively longer than measurement from western countries. The lengths of sigmoid colon and mesocolon also increases with age and this may possibly be the anatomical basis for the frequent occurrence of sigmoid volvulus and failed colonoscopy among the older population in our environment.
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- Akhator, A, Umukoro, D (2007) Sigmoid volvulus in mid western Nigeria. Niger J Surg Sci 17: pp. 59-62
- Akinkuotu, AA, Samuel, JC, Msiska, N, Mvula, C, Charles, AG (2011) The role of the anatomy of the sigmoid colon in developing sigmoid volvulus: a case–control study. Clin Anat 24: pp. 634-637 CrossRef
- Bassey, DE (1993) Radiological observations in the colon of Nigerians with chronic enema abuse. East Afr Med J 70: pp. 452-454
- Bhatnagar, BNS, Sharma, CLN, Gupta, SN, Mathur, MM, Reddy, DCl (2004) Study on the anatomical dimensions of the human sigmoid colon. Clin Anat 17: pp. 236-243 CrossRef
- Brown, JL, Khan, N, Moore, LA Large intestine. In: Borley, NR, Standring, S eds. (2010) Gray's anatomy: the anatomical basis of clinical practice. Churchill Livingstone, Edinburgh, pp. 1147-1148
- Bruusgaard, C (1947) Volvulus of the sigmoid colon and its treatment. Surgery 22: pp. 466-478
- Burkitt, D (1981) No relation of sigmoid volvulus to fiber content of African diet. N Engl J Med 304: pp. 914
- Masri, SH Volvulus. In: Adeloye, A eds. (1987) Davey's companion of surgery in Africa. Churchill Livingstone, Edinburgh, pp. 335-348
- Grossmann, EM, Longo, WE, Stratton, MD, Virgo, KS, Johnson, FE (2000) Sigmoid volvulus in Department of Veterans Affairs Medical Centers. Dis Colon Rectum 43: pp. 414-418 CrossRef
- Hanson, ME, Pickhardt, PJ, Kim, DH, Pfau, PR (2007) Anatomic factors predictive of incomplete colonoscopy based on findings at CT colonography. Am J Roentgenol 189: pp. 774-779 CrossRef
- Heis, HA, Bani-Hani, KE, Rabadi, DK, Elheis, MA, Bani-Hani, BK, Mazahreh, TS, Bataineh, ZA, Al-Zoubi, NA, Obeidallah, MS (2008) Sigmoid volvulus in the Middle East. World J Surg 32: pp. 459-464 CrossRef
- Jit, I, Grewal, SS (1975) Length of small and large intestines in North Indian subjects. J Anat Soc India 24: pp. 89-100
- Kohn, GJ, Rosnequist, CJ, Lawson, MJ (1992) Diverticular disease and sigmoid colon length in southeast Asians and Caucasians. Med Sci Res 20: pp. 407-408
- Lal, SK, Morgenstern, R, Vinjirayer, EP, Matin, A (2006) Sigmoid volvulus an update. Gastrointest Endosc Clin N Am 16: pp. 175-187 CrossRef
- Madiba, TE, Haffajee, MR (2010) Anatomical variations in the level of origin of the sigmoid colon from the descending colon and the attachment of the sigmoid mesocolon. Clin Anat 23: pp. 179-185
- Madiba, TE, Haffajee, MR (2010) Sigmoid colon morphology in the population groups of Durban, South Africa, with special reference to sigmoid volvulus. Clin Anat 24: pp. 441-453 CrossRef
- Madiba, TE, Haffajee, MR, Sikhosana, MH (2008) Radiological anatomy of the sigmoid colon. Surg Radiol Anat 30: pp. 409-415 CrossRef
- Manzini, VT, Madiba, TE (2006) Sigmoid volvulus in KwaZulu-Natal Teaching Hospitals: preliminary results. S Afr Med J 96: pp. 732
- Moore KL, Dalley AF (1999) Abdomen. In: Moore KL, Dalley AF (eds) Clinically oriented anatomy. Lippincott, Philadelphia, pp 174–330
- Nuhu, A, Jah, A (2010) Acute sigmoid volvulus in a West African population. Ann Afr Med 9: pp. 86-90 CrossRef
- Raveenthiran, V, Madiba, TE, Atamanalp, SS, De, U (2010) Volvulus of the sigmoid colon. Colorectal Dis 12: pp. e1-17
- Sadahiro, S, Ohmura, T, Yamada, Y, Saito, T, Taki, Y (1992) Analysis of length and surface area of each segment of the large intestine according to age sex and physique. Surg Radiol Anat 14: pp. 251-257 CrossRef
- Saunders, BP, Fukumoto, M, Halligan, S, Jobling, C, Moussa, ME, Bartram, CI, Williams, CB (1996) Why is colonoscopy more difficult in women?. Gastrointest Endosc 43: pp. 124-126 CrossRef
- Saunders, BP, Masaki, T, Swada, T, Halligan, S, Phillips, RK, Muto, T, Williams, CB (1995) A preoperative comparison of Western and Oriental colonic anatomy and mesenteric attachments. Int J Colorectal Dis 10: pp. 216-221 CrossRef
- Schembre, DB, Ross, AS, Gluck, MN, Brandabur, JJ, McCormick, SE, Lin, OS (2011) Spiral overtube-assisted colonoscopy after incomplete colonoscopy in the redundant colon. Gastrointest Endosc 73: pp. 515-519 CrossRef
- Shah, HA, Paszat, LF, Saskin, R, Stukel, TA, Rabeneck, L (2007) Factors associated with incomplete colonoscopy: a population-based study. Gastroenterology 132: pp. 2297-2303 CrossRef
- Shepherd, JJ (1969) The epidemiology and clinical presentation of sigmoid volvulus. Br J Surg 56: pp. 353-359 CrossRef
- Tegegne, A (1995) Cultural bowel patterns and sex difference in sigmoid volvulus morbidity in an Ethiopian hospital. Trop Geogr Med 47: pp. 212-215
- Williams PL, Bannister LH, Berry MM et al (1995) Gray's anatomy, 38th edn. Churchill Livingstone, Edinburgh, pp 1777–1778
- Yamazaki, S, Yamazaki, K, Miyazaki, T (1994) An analysis on the length of the large intestine and its internal diameter amongst the Japanese. Japan Soc Coloproctol 47: pp. 31-39 CrossRef
- Title
- The role of the anatomy of the sigmoid colon in developing sigmoid volvulus: a cross-sectional study
- Journal
Surgical and Radiologic Anatomy
Volume 35, Issue 3 , pp 249-257
- Cover Date
- 2013-04-01
- 10.1007/s00276-012-1037-5
- Print ISSN
- 0930-1038
- Online ISSN
- 1279-8517
- Publisher
- Springer-Verlag
- Additional Links
- Topics
- Keywords
- Sigmoid colon
- Sigmoid volvulus
- Colonoscopy
- Dimension
- Nigeria
- Industry Sectors
- Authors
- Olusegun Isaac Alatise (1)
- Olusegun Ojo (2)
- Polycarp Nwoha (3)
- Ganiyat Omoniyi-Esan (2)
- Abidemi Omonisi (2)
- Author Affiliations
- 1. Department of Surgery, College of Health Science, Obafemi Awolowo University, PMB 5538, Ile-Ife, Osun, Nigeria
- 2. Department of Morbid Anatomy, College of Health Science, Obafemi Awolowo University, Ile-Ife, Osun, Nigeria
- 3. Department of Anatomy and Cell Biology, College of Health Science, Obafemi Awolowo University, Ile-Ife, Osun, Nigeria


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A robotic system with a common software and hardware platform for integration of a variety of modular components is provided that can be set up for a given application and reconfigured to address changing needs. Modules attach to the robotic platform with standard interfaces in order to maximize the platform's flexibility. Robotic arms also have interchangeability such as variable pitched Z-racks, powder handling or other technologies. The standard interfaces allow third party developers to develop and integrate their own custom modules. One module included with the robotic platform in accord with this invention is a module that both weighs and images a sample.
1. A robotic system, comprising:
a) a frame,
b) a plurality of interfaces, wherein at least two of said interfaces are substantially identical to one another, and
c) a plurality of modules supported by the frame, each of the modules connecting into at least one of said interfaces, the plurality of modules having top plates that together form a work surface,
wherein at least one of said modules is a weigh and image module adapted to weigh and image a sample.
2. The system of
3. The system of
4. The system of
5. The system of
6. The system of
7. The system of
8. The system of
9. The system of
10. The system of
11. A module for automated weighing and imaging of a sample, the module comprising
a top plate, bottom platform and side supports connecting the top plate and bottom platform, the top plate having a door;
a sample chamber located beneath the door, the sample chamber comprising a diffuser;
a balance on the bottom platform;
a sample holder positioned on the balance directly below the door, the sample holder defining the bottom of the sample chamber; and
a digital camera with a lens focused on a sample held by the sample holder positioned on the balance directly below the door.
12. The module of
13. The module of
14. The module of
15. The module of
16. The system of
17. The system of
18. The system of
19. The system of
20. A module as set forth in
21. A robotic system comprising:
a frame;
a plurality of modules supported by the frame, wherein at least one of the modules is a weigh and image module adapted to weigh and image a sample;
locators supported by the frame, the locators being engageable with the modules for accurately locating the modules relative to the frame;
a robot supported by the frame and movable with respect to the modules;
a housing supported by the frame and housing electronic equipment; and
interfaces on the housing for interfacing with the electronic equipment, the modules being connected to respective interfaces;
wherein the top plates form a substantially continuous work surface.
22. The system of
23. The system of
24. The module of
25. The module of
This application claims the benefit of U.S. Provisional Application No. 60/795,788 filed on Apr. 28, 2006, which is incorporated herein by reference for all purposes.
This invention relates to a modular robotic workstation capable of performing a multitude of functions, with the workstation including a module having the capability of both weighing and capturing the image of a sample. The robotic workstation has a modular design, meaning a plurality of modules can be plugged into the workstation to create different configurations, as desired.
Automation is well established within the pharmaceutical discovery research departments. Over the past several years, there have been efforts to apply automation and high throughput techniques into various development labs in which automated systems have been set up to serve dedicated workflows. For example, there are a number of automated reactor systems that have been used for synthesis screening and process optimization. See, for example J. Am. Chem. Soc. 2003, 125, 4306-4317; "An Automated Approach to Process Optimization, Parameter Setting, and Robustness Testing" Organic Process R&D 2001, 5, 331-334; J. Am. Chem. Soc. 2002, 124, 15280-15285; "Automated Workstations for Parallel Synthesis" Organic Process R&D 2002, 6, 833-840; "Parallel solid-phase synthesis, screening, and encoding strategies for olefin-polymerization catalysts." Tetrahedron 1999, 55(39), 11699-11710; "An integrated high-throughput workflow for pre-formulations: Polymorphs and salt selection studies" Pharmachem, 2003, 1(7/8); and "Application of high throughput technologies to drug substance and drug product development" Computers and Chem. Eng. 2004, 28, 943-953.
While these examples highlight that automation has been successfully applied to dedicated workflows, there is a need for more flexible automation systems. Others have proposed robotic systems having interchangeable parts, including robotic arms, reaction vessels and reaction vessel arrays. See, e.g., WO 98/40159. These systems have proven too complex to be easily customizable for application to a variety of chemical workflows.
In addition, others have produced automated weighing systems, such as the Balance Automator from Mettler Toledo, Inc. This system however performs only one function (automated sample weighing) and is not modular.
The invention provides apparatus and systems that comprise a robotic platform with a common software and hardware platform for integration of a variety of modular components that can be set up for a given application and reconfigured to address changing needs. Modules attach to the robotic platform with standard interfaces in order to maximize the platform's flexibility. Robotic arms also have standard interfaces for interchangeability such as variable pitched Z-racks, powder handling or other technologies. Optionally, a third robotic arm can be added. The standard interfaces allow third party developers to develop and integrate their own custom modules. One module included with the robotic platform in accord with this invention is a module that both weighs and images a sample.
The details of embodiments of the invention are set forth in the accompanying claims, drawings and description, below. Other features, objects, and benefits of the invention will be apparent from the description and drawings.
In the present invention, systems and apparatus comprise a configurable three axis Cartesian robot, pump housing, and deck which can be outfitted with various functional modules. This configurable architecture allows users to customize the hardware for specific workflows by adding the appropriate modules to the basic robot platform. This robot system further comprises additional functionality selected from the group consisting of parallel overhead stirring, viscous dispense tips, friction/force probes, high temperature dispense tips, vial grippers, plate grippers, pH probes, and a variety of configurable deck modules including a balance for feedback control of viscous materials dispensing, heating/cooling/stirring zones, vortexing zones, and a sample imaging station. Robot configurations range from a simple general purpose liquid handling robot to a configuration that also includes the sample processing and analytical capabilities required for a complex workflow.
Modules attach with standard interfaces in order to maximize the platform's flexibility. Robotic arms also have standard interfaces for interchangeability such as variable pitched Z-racks, powder handling or other technologies. There are typically two robotic arms, and optionally, a third robotic arm can be added. The standard interfaces allow third party developers to develop and integrate their own custom modules.
One embodiment of the invention includes a robotic system, comprising: a) a frame optionally comprising a backplane, front, and sides. The frame can form a deck outline adapted to receive a plurality of modules associated with the frame. The frame can also comprise a base adapted to receive a plurality of modules, with the modules having top plates that combine to form a work surface. The arms of the robotic system are supported by the backplane or a framework extending from the base. The robotic system also comprises, b) a plurality of interfaces associated with the frame, wherein at least two of said interfaces are identical to one another and c) a plurality of modules, each of which connects into at least one of said interfaces, the plurality of modules having top plates that together form at least a portion of a deck or work surface. At least one of the modules is adapted to both weigh and image a sample. The robotic system can include one or more additional modules selected from the group consisting of a vortexing module, a heat and stir module, a wash station module, a reagent holder module and a heating module. The robotic system may have other features that are generally of a nature similar to those that have been described in the past, For example, the system may incorporate a plurality of pumps, such as syringe pumps.
The invention also provides a weigh and image module having a top plate with a door that opens and closes to reduce wind impact on measurements and allow for more accurate weight measurements. The weigh and image module includes a digital camera and optionally one or more lights below the top plate focused on the sample nest of a balance also located below said top plate. A diffuser surrounds the sample holder/nest on the balance and defining a sample chamber, and the diffuser can be colored and/or include a ruler to measure a sample property (such as color, settling, etc.). The weigh and image module includes a bottom platform attached to the top plate by a side support, with the bottom platform supporting the camera and balance, and being adapted to substantially isolate the balance from vibration.
One of the benefits of the combined weigh and image module is in the training of the robot for sample positioning on the balance. A user typically wants to repeatedly, accurately position a sample on the balance to ensure repeatability. However, because the balance is located below the deck (i.e., below the top plate), the camera can be used to position the sample to the correct location, which is then trained into the software for the robotic system. In this regard, the camera is used in a live image mode, with the user positioning the robotic arm with the gripped sample in the sample chamber on the balance nest using the camera live image view to position the sample. Once the position is identified, the robotic software trains that particular position that can be recalled during automated weighing protocols.
Looking at
The backplane housing 18 comprises interfaces and support (e.g., racks) for pumps or other ancillary electronic equipment needed for the workflow. Such interfaces and supports are typically for inexpensive, off-the-shelf syringe pumps, peristaltic pumps, switching valves, or any other electronic equipment for other parts of the robotic system (e.g., such as a heated tip on the robotic arm). An optional information display may be added to the back plane housing 18, allowing a user to monitor critical information such as temperature, stirring speed or other user defined variables. In circumstances where a dedicated computer is not used to run the robotic system, this optional display can function to provide the user information from the firmware.
Continuing with
For example, as shown in
Looking specifically at the modules that are attached to the robotic system, a weigh and image module 30 is shown in
A camera 40 is mounted on the lower platform 38 having a lens 42 focused in the direction of the sample chamber 70, which comprises sample 74. The camera is typically a charged coupled device (e.g., a digital camera) for high resolution picture and/or video capture. For example, a Mutech Corp. P/N PC-1280/C or a Phoenix PC-1280 USB which has a resolution of 1280-1024 may be used. The lens typically has a deep enough depth of field to accommodate a range of sample sizes, but an autofocus lens with desired zooming capability appropriate to focus on the samples in the chamber can also be used. For example, a ZOOM, TOYO OPTICS, 12.5-75 MM lens may be used. Associated with the camera 40 and lens 42 are lights 46, with two lights 46 being shown in
Another module is a heated and stirred module having the ability to heat 3 microtiter plates up to 200� C. and magnetically stir liquid samples in each well of the microtiter plate at speeds of up to 750 RPM. This module comprises an independent over-temperature control circuit to disconnect power in the event of an anomalous thermocouple reading or component failure. Other modules for the deck include a 0.01 mg resolution balance, a vortex stirrer, a vertical shaker for powder mixing, and several different types of standard wash stations.
Users control the robotic system using a robotic control system, which typically includes software for both protocol development and execution. Software useful in the robotic control system is Renaissance Impressionist� and Epoch� software, available from Symyx Technologies, Inc. (Santa Clara, Calif.). Renaissance Impressionist� Software is a general laboratory automation package for creating and executing laboratory procedures. Epoch typically records log files, and writes data from the balance, the camera, and any pH or conductivity probes back to the database. Each module of the robotic system will include an Impressionist software resource which defines the underlying communications protocols for each device contained within a particular module. For example, the weigh and image module has resources for camera, the weigh cell, and you define each of the digital inputs/outputs (I/O) points for the each of the connections (as described above). Also for example, the heated and stirring module has resources for a stir motor controller, heater controller and over temperature controller. Configuring Impressionist for a specific module configuration is accomplished by selecting those resources that correspond to the hardware devices connected to the interfaces. This approach allows devices of the same type (e.g., Watlow temperature controller or an Omega Temperature controller) to be used interchangeably by user procedures even if the underlying communications protocols are different. Renaissance Impressionist currently supports over 140 resources that manage communications with individual hardware devices. In addition, users can extend capabilities to new modules by using the Impressionist Developer's Kit, which allows users to develop their own custom resources to be used with any proprietary or custom modules.
The robotic system is designed to be the central enabling technology of many different workflows. One method of using the robotic system is in a liquid formation workflow, which accelerates the process of making solubility measurements in addition to preparing and testing liquid formulations, starting from either solid forms or solutions of active pharmaceuticals and intermediates. Robotic activities include dispensing solvents and buffers, measuring or adjusting the pH, heating, cooling, stirring and filtering samples, and making serial dilutions for subsequent chromatography measurements.
In one method of using the system, components of liquid formulations to be prepared are identified using a library design package, such as Library Studio (available from Symyx Technologies, Inc., Santa Clara, Calif.) or design of experiments software or other means. The design is not critical to this invention. The user defines the resources available to the robotic system (such as the number of arms, syringe pumps, vial grippers, plate grippers, temperature modules, vortexers, heaters stirrers, etc.). As part of defining the resources, a user will also specify a communication channel for each resource, so that the robot control system will know which signals to trigger the desired action; in other words, each resource will have a specified software address. The user will also typically train each available robotic arm to a reference position, which is an X-Y-Z space within the workspace and can be a point on the deck (such as a screw location). The reference position allows the user to identify any substrate relative to the reference point, which then provides the substrate reference to all available arms and resources. The user will then define the physical locations on the deck or in the range of the robotic arms. The locations are typically defined as an array or an individual vial. A user typically will manually train individual locations of each substrate, which can be retained for repeated use (such as source vial locations, destination vial locations, wash stations, balance location, etc.). For the weigh and image module, the sample nest is trained (as described above), but also the image capture parameters are set by setting aperture, color balance and light intensity (e.g., should one light or two lights should be on during image capture). Once the desired formulations are identified or conceived, the source materials are typically set on the deck in specified locations and a destination array of individual vials are set on the deck at a designated location, known to the software and user. An Impressionist/Epoch dispense protocol is used to recall the recipe and in this example, the first component is dispensed according to the recipe. After all the dispenses, the robot system then tares the balance, picks up a sample vial using a vial gripper tool, opens the draft door, moves the vial to the balance nest, opens the grippers, retracts the arm and closes the draft door. The software waits for a stable weight, during which time the image is captured by the lights activating and the camera recording the image to the database. In another example, an aliquot of a suspension formulation is taken from an array into a second array. The weight of each aliquot is taken and an image is taken at a first time. The array of aliquots is processed as desired, such as waiting for a period of time to allow for settling or heating or other processing. The aliquots are weighed and imaged again to look for mass loss due to evaporation and changes in the formulation.
A number of embodiments of the invention have been described. Nevertheless, it will be understood that various modifications may be made without departing from the spirit and scope of the invention.
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|College Basketball Odds: Oklahoma State at Texas Spread, Picks & Public Bets
|Written by Anthony Rome
|Thursday, 13 March 2008 18:11
Texas After a Big 12 Title
Texas has accomplished a lot since Rick Barnes took over in 1998, but it's never won the Big 12 tournament.
The sixth-ranked Longhorns begin their push for their first Big 12 tourney title when they meet Oklahoma State in the quarterfinals on Friday.
Oddsmakers from Bodog have made Texas –7.5 point spread favorites (View College Basketball odds) for today's game (Game Matchup). Current public betting information shows that 88% of bets for this game have been placed on Texas -7.5 (View College Basketball bet percentages).
Texas (26-5) has lost the last two finals of this event to Kansas, and the teams could be in line for another meeting. Both squads shared the regular-season crown, although the Longhorns are the top seed by virtue of their 72-69 win over the Jayhawks on Feb. 11.
"I want them to feel good about it, but the time to celebrate is when it's all said and done," said Barnes about sharing the title. "We've still got work to do."
Texas also lost in the final in 2001 and 2004, but went to Barnes' first Final Four in between in 2003. The coach has guided the Longhorns to a school-record 26 regular-season wins this season, and was named Big 12 coach of the year, although he was quick to deflect that honor.
"The credit goes to our players," Barnes said. "They've put in the time and do what it takes to be successful."
The success wasn't necessarily expected after Texas lost national player of the year Kevin Durant to the NBA. The Longhorns, however, had the rest of their starters back, although they have been using basically a six-man rotation down the stretch due to their lack of depth.
"The last three games have been pretty hard games to play because we've played against teams that have mostly perimeter guys out there," Barnes said. "So we haven't been able to use our big guys because of some matchups."
Barnes will face that same problem since the Longhorns used a short bench in the regular-season finale, a 62-57 win over Oklahoma State (17-14) on Sunday. D.J. Augustin scored 20 points and Damion James added 12 for the Longhorns, whose reserves played a total of 22 minutes.
Augustin has been the catalyst for both of Texas' wins over Oklahoma State this season. The sophomore guard scored 26 points in a 63-61 road win over the Cowboys on Jan. 21.
Oklahoma State has won six of its last eight games, and Texas figures the third meeting between the teams will be another challenge.
"You just look at their team in general, they just really got aggressive, they're driving the ball," Barnes said. "That turnaround is really impressive."
The Cowboys bounced back from the loss to Texas by advancing with a 76-72 first-round win over Texas Tech on Thursday. Freshman James Anderson scored 18 points and made two clinching free throws with 4 seconds to go.
The Cowboys overcame a shaky defensive performance in which they allowed the Red Raiders to shoot 54.7 percent - the second-worst mark allowed by Oklahoma State this season. They allowed Texas to shoot just 36.1 percent in the first two meetings this season.
"We've played them well both times," said Oklahoma State coach Sean Sutton about playing Texas. "They've just made a few more plays than us at the end of the game."
This is the second straight year these teams are meeting in the Big 12 tournament. Texas won 69-64 in last season's semifinals.
by: Staff Writers - Email Us
More NCAA College Basketball Coverage from theSpread.com
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