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- Work 1-844-731-1086
- San Diego, CA
- 32.7193545 -117.1565227
- Work 1-858-371-3294
- San Diego, CA
- 32.988819898637 -117.09005588493
- Work 1-844-731-1095
- San Diego, CA
- 32.775161336116 -117.14260736041
- Work 1-844-727-9749
- San Diego, CA
- 32.760433 -117.175577
2 Bay Ho Neighborhood Apartments For Rent
We found 2 apartments for rent in the Bay Ho neighborhood of San Diego, California. Refine your search by using the filter at the top of the page to view 1, 2 or 3+ bedroom apartments for rent in Bay Ho as well as cheap apartments, pet friendly apartments, apartments with utilities included and more. Use our customizable guide to refine your options for apartments in Bay Ho and find exactly what you want during your San Diego, California apartment search.
Pacific Bay ClubExact - 4070 Huerfano Avenue San Diego, CA 9211732.815845357907 -117.21711106387+−Preview DetailsCollapse Details
Pacific Bay Club offers junior, one, and two bedroom apartment homes for rent equipped with functional features so necessary in our fast-paced world and all the amenities that you will be glad to come home to. For your enjoyment there is a lovely pool and jacuzzi, barbecue areas and a fitness center.
- Studio, 1 & 2 Bedrooms
- Fitness Center
- Close to the Beach
- Excellent Central Location
- Assigned Covered Parking
- Easy Freeway Access
- Dishwasher In Select Homes
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- Private Patios & Balconies
Villa Monair
3730 Southview Dr | San Diego, CA See Other ICI Mgmt. Communities
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Latin America
Andrés Rivera's El farmer was a best-seller in 1996. The novel concerned the declining years of the legendary 19th-century Argentine dictator Juan Manuel de Rosas. The work was centred on a winter's night of recollections, with Rosas's rambling monologue bringing back to life for him the glories of his reign and the perfidy of his enemies. In the process he articulated fragments of a modern ideology of authoritarian control.
Tununa Mercado's La madriguera focused on the author's childhood. The work was not autobiographical in any common sense of the word, however, but rather involved a feminist theory of memory.
Jorge Salessi's Médicos maleantes y maricas: higiene, criminología y homosexualidad en la construcción de la nación Argentina (Buenos Aires, 1871-1914) exemplified the work being done to provide an adequate social history for Latin America, which often meant dealing with topics that official scholars had avoided. Salessi's work was concerned with the public discourse regarding sexual deviance and the police and with medical responses to it.
Reina Roffé's El cielo dividido interwove the stories of seven Argentine women. The account of their lives, in addition to being an impressive attempt to record a mosaic of women's history in Argentine society, connected their personal narratives with national political discourse. In the process Roffé provided a lucid explanation of the way in which history in Argentina has referred only to the lives of men or to women only as figures in the lives of men.
Gabriel García Márquez's Noticia de un secuestro was published simultaneously in numerous Latin-American centres, a growing practice with authors of his stature. Continuing his interest in violence and codes of masculinity, García Márquez explored the kidnapping of a prominent woman ordered by the drug czar Pablo Escobar. The author combined documentary sources and narrative re-creations to fashion a testimonial on the social contradictions of Colombia.
Fernando Vallejo's Chapolas negras was a biography of a short-lived 19th-century Colombian poet, José Asunción Silva. The poet was associated with the beginnings of a decadent, bohemian cultural tradition in Latin America, and Vallejo's interest in him continued the series of explicitly homosexual novels he had published.
First published in Spain in 1995, Reinaldo Arenas's posthumous Adiós a Mamá was published in the U.S. in 1996. A few of the stories were written in Cuba before Arenas's escape with the Marielitos, but most were written during the 10 years he resided in the U.S. These bitter stories, which reflected Arenas's interest in his later works with exile and with the lives of homosexuals, had to do with individuals who were unable to identify with the dominant social structures and felt a sense of alienation.
Rafael Loret de Mola's potboiler Alcobas de palacio was one of the fiction hits of the year in Mexico. The author's trashy novel exemplified one more element of U.S. influence: the luridly sexual as an index for political corruption.
Elena Garro continued as the reigning matriarch of feminist writing in Mexico. Her Busca mi esquela & Primer amor consisted of two short novels. The first related an erotic relationship between a young woman and an older man, a theme that Garro treated with her customary acerbic view of the limits of human aspirations. The second had a post-World War II setting in a summer vacation retreat in France at which the ugly history of the war could not be kept at bay by a newfound hedonism.
In late 1995 Carlos Fuentes published La frontera de cristal. Fuentes had in his fiction established a vast mosaic of contemporary Mexico, and he examined various social and political issues via stories and novels that continued to bear his customary mark of sharp insight and fluid storytelling. The stories of the collection dealt with migration, the issue that continued to sour relations between Mexico and the U.S. The ways in which Mexicans viewed U.S. border policy--as racism, economic exploitation, and linguistic and cultural jingoism--were represented. Magali García Ramis's Las noches del Riel de Oro was a collection of short stories that developed the author's interest in the cultural and social contradictions of Puerto Rico's divided identity as a Latin-American country that was also a political unit of the U.S. García Ramis emphasized women's lives.
Mayra Santos Febres's Pez de vidrio was a fine collection of short stories describing the experiences of women in San Juan, the capital of Puerto Rico. There had been a considerable amount of women's writing in recent years in Puerto Rico, and this collection confirmed the interest of those authors in turning away from the representation of women in traditional women's spaces (the home, the church, the school, the convent) and placing them instead not only in strategic positions in public life but also in urban life, where so many changes in women's lives in recent decades had taken place.
Portuguese fiction had a vintage year in 1996. The number of novels published was not higher than in previous years, but the quality of work produced by well-known authors was outstanding. Alexandre Pinheiro Torres, a distinguished academic, completed a remarkable fresco of Portuguese society under the Salazar regime with the publication of A quarta invasão Francesa, a fascinating tale of intrigue that ends in a political assassination. The project started in 1977 with A nau de Quixibá and developed into five novels depicting 50 years of contemporary Portuguese life.
The Association of Portuguese Authors awarded the Great Prize for Fiction to Teolinda Gersão for her novel A casa da cabeça de cavalo, a subtle tale of women's feelings as seen through three generations. In a remote and provincial town, where the presence of an outsider upsets the stability of daily life, women nurture their passions in silence, imposed by a patriarchal society that resists change. A clandestine language is invented between two lovers who have been tricked by paternal authority. Conventions are slowly eroded, and when freedom dawns on the people, they are emotional cripples.
José Saramago published his long-awaited novel Ensaio sobre a cegueira, a hallucinatory tale that was also a dramatic warning on the ills of contemporary society. His characters and the place of action are nameless. Characters are known for the functions they perform, and the events described may have taken place anywhere and nowhere. A strange epidemic of blindness gradually strikes a whole community, sparing only the woman who witnesses it all. To avoid the spreading of the disease, the government sends soldiers to contain the blind in a ghetto. A group of bullies takes over and rules in an orgy of brutality and rape that tests human emotions beyond endurance. As inexplicably as the blindness had started, people begin to recover their eyesight, while the woman fears the moment when the disease might start again, making her one of its victims. It is a philosophical tale of feverish dramatic intensity on the moral blindness of humans and the perversities of their behaviour that seem to be leading to self-destruction.

subset: commoncrawl


text:
I can add plugin for Wordpress or not??? I like idea make website for selling I'm author next submit my first website
help meeee!!!!!! please
It depends on what the plugin does. On the whole it is ok assuming you have permission and any necessary licenses from the author/creator
I can add plugin, but link where download plugin in documentation, I can make it???
Something like this would be better if you coded and made it yourself for the theme BUT if you want to use this one in your theme then you MUST have permission from the author of the plugin to use it.
I have a dude…... I can make my hand for example create plugin for Wordpress????? and too programmer
Sorry do not understand. You can:
- Create you own plugins on their own for sale on Codecanyon
- Create your own version of this plugin and add it to your theme for sale on Themeforest
- You can use this one in your theme AS LONG AS YOU HAVE PERMISSION from the original devleopers
Sorry, my bad english…... I understand your last message
I can make a plugin original?????
Yes but if it is to be part of your theme it would be better to write it straight into the theme options rather than have it as a plugin
Yes but if it is to be part of your theme it would be better to write it straight into the theme options rather than have it as a plugin
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text:
Speakers Corner
It's free to register, to post a question or to start / join a discussion
Too Many Gold Medal Winners.
« previous 1 2 3 next »
Likes # 0
Posted August 20, 2012 at 9:42PM
I heard a rumour that because there are so many gold medal winners at the Olympics, that it may not be possible for them all to be honoured in the New Year's Honours List... Ahhhh! what a shame.
Who will they choose then?
Likes # 0
Posted August 21, 2012 at 3:42PM
How many people actually know who they're voting for? Most people just vote for a party
Likes # 0
Posted August 21, 2012 at 5:29PM
fourm member
*I get the impression you have a particular incident in mind that makes you say Coe was a poor MP in spite of the election result not supporting that view.
Do tell, please.*
Actually I can find nothing about his parliamentary career online, not a thing. Which isn't really much to show for 5 years in office
Likes # 0
Posted August 21, 2012 at 7:43PM
too many micky mouse sports in the olympics now.
sandpit volleyball, will womens wrestling will be moved to a mud pit in brazil, sync swimming, horse dressage, football, tennis, etc
wait till they include darts and snooker.
Likes # 0
Posted August 21, 2012 at 9:16PM
I suppose it all depends on what you quantify as a sport. I'm pretty sure that those that can hit 180 on a regular basis could argue that their skill is on a par with lets say archery or shooting both of which are Olympic sports. Billiards in its various forms are presently on the Olympic list for consideration but are unlikely for inclusion before 2020. Snooker may also be part of that consideration. As someone who plays competitive pool I can vouch that top players are indeed very skilful.
Golf, Rugby Softball & Baseball are all also under consideration and why not. Thousands of people play these games in virtually all countries of the world.
Perhaps you could give us your views on what are not in your opinion "mickey mouse sports"
Likes # 0
Posted August 21, 2012 at 9:42PM
Condom you said:
"Golf, Rugby Softball & Baseball are all also under consideration and why not"....
I'll tell you why those sports are not worthy of Olympic inclusion...
'cos it's only mainly rich people that can afford the aforementioned sports...but I'll will nevertheless endorse Darts 'n' Pool as I am still in a strict training regime for Rio and/or beyond. [BTW I don't want a knighthood if I win a Gold ... a life-size bronze statue will do].
Likes # 0
Posted August 21, 2012 at 9:45PM
I played rugby, softball & baseball at school, and I went to a comprehensive.
I wouldn't say Rugby League was in any way a rich person's sport.
Now Golf, that's just a good walk spoiled...
Likes # 0
Posted August 21, 2012 at 10:04PM
I understood that golf was already nailed on to be part of the Rio Olympics. As for it being a good walk spoiled, well obviously you have never played it. Skill is needed in abundance to become a top player. Even top amateurs are very skilful. I started playing golf when I was 68 years old and loved it. I was useless at it but as a pastime and an exercise it is ideal. I haven't mentioned the social side which is also excellent.
Yes it costs more than playing footie in the park for youngsters, but it is within reach. A lot of clubs help youngsters get started. I would hazard a guess that it would cost their parents less to kit them out for golf, than they already pay for computer games to keep them sat on their backsides all day and night.
But I agree some sports should not be in the Olympics. But if it goes on audience participation then we should be pushing for fishing. The percentage of people who fish compared to those who do synchronised drowning must be pretty enormous. Javelin throwing is only darts on a larger scale and not as accurate, so maybe the darts players should be able to strut their stuff too.
Likes # 0
Posted August 21, 2012 at 10:06PM
Sorry darts are out... Playing without the stimulant of alcohol would make them look pretty poor players. In fact I don't think they could do it.
Likes # 0
Posted August 21, 2012 at 10:14PM
...I'll concentrate on pool then. [All variations]
Likes # 0
Posted August 21, 2012 at 10:18PM
Although I enjoyed the Olympics, there is a danger of an ever expanding portfolio of "sports", such that the cost of putting on the games is such that few countries can afford it. Some believe that the games should be radically cut back so that only athletics are involved - in the spirit of the original games.Other sports would continue to have their world championship. In this scenario they could be permanently held in Greece, with all participants paying their share.I do not share this view, but I do think that there should be fewer, rather than more, "sports" included. Football, tennis, beach volley ball, trap shooting are all ,perhaps, be considered for the chop, and darts, snooker etc should not, IMHO, be added. However skillful some may be, the test should be that of physical difficulty and need to train hard.
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Australian Open - Day 3
Similar imagesView all
A TILT AND SHIFT LENS WAS USED IN THE CREATION OF THIS IMAGE.)... News Photo2012,Australia,Australian Golf Open,Bestof,Golf,Golf Course,Horizontal,Mathew Goggin,Round Three,Sport,Sports Activity,Sydney,Taking a Shot - Sport,Topics,TopixPhotographer Mark KolbeCollection: Getty Images Sport 2012 Getty ImagesSYDNEY, AUSTRALIA - DECEMBER 08: (EDITORS NOTE: A TILT AND SHIFT LENS WAS USED IN THE CREATION OF THIS IMAGE.) Matthew Goggin of Australia plays a fairway shot during round three of the 2012 Australian Open at The Lakes Golf Club on December 8, 2012 in Sydney, Australia. (Photo by Mark Kolbe/Getty Images)


text:
A system is disclosed for producing images representing radiation dose distributions in order to verify the radiation dose applied to a target area. The system uses a phantom assembly constructed of material that is the radiological equivalent of live tissue. The phantom assembly has slits where radiation sensitive film can be inserted and can include a channel for an insertable radiation generating device. The treatment dose is then applied to the phantom and the radiation sensitive film records the dose. A CCD camera microdensitometer is then used to read the exposed radiation sensitive film. The CCD camera microdensitometer includes a computer system which processes the image to remove artifacts and generates isodose contours for the radiation treatment applied. In addition, several pieces of radiation sensitive film in different planes can be exposed and processed in order to produce images representing the radiation dose distribution in three dimensions.
1. An microdensitometer system for reading an image recorded on radiation sensitive film, said microdensitometer system comprising:
camera means, directed along an imaging axis, for producing image signals representative of said image, said camera means including a planar array of CCD sensing elements extending transverse to said imaging axis,
illumination means for producing light uniformly across an imaging plane extending transverse to said imaging axis, said illumination means including an array of light producing elements, a stable voltage reference and a light control means coupled to said array of light producing elements and said stable voltage reference, said light control means including means for sensing the light output of at least one of said light producing elements and means for controlling a level of current to each of said light producing elements in response to said sensed light output,
alignment means for adjustably aligning said camera means with respect to said illumination means along said imaging axis.
2. A microdensitometer system according to claim 1 wherein the wavelength of the light producing elements is substantially the same as the peak absorption wavelength of said radiation sensitive film.
3. A microdensitometer system according to claim 2 wherein the wavelength of the light producing elements is 660 nanometers.
4. A microdensitometer system according to claim 1 wherein said illumination means includes a plurality of groups of light producing elements arranged in an array, and said light control means controls the current level applied to each group of light producing elements.
5. A microdensitometer system according to claim 4 wherein each of said groups are annular groups with respect to a central location of said array and the current level applied to at least one group is different from the current level applied to any other group.
6. A microdensitometer system according to claim 5 wherein at least one of said groups is further arranged into two or more subgroups and the same current level is applied to each of said subgroups in said group.
7. A microdensitometer system according to claim 5 comprising three annular groups of light producing elements, an inner group adjacent to said central location of said array, a middle group substantially surrounding said inner group and an outer group substantially surrounding said middle group, and said light control means controls the current level applied to each group, and the current level applied to at least one group is different from the current level applied to any other group,
said outer group is further arranged into at least four subgroups and the same current level is applied to each of said subgroups in said outer group,
said middle group is further arranged into at least four subgroups and the same current level is applied to each of said subgroups in said middle group, and
said inner group is further arranged into at least two subgroups and the same current level is applied to each of said subgroups in said inner group.
8. A microdensitometer system according to claim 1 wherein said light producing elements are arranged in a circular array.
9. A microdensitometer system according to claim 1 wherein said light control means comprises photosensing means for monitoring the intensity of at least one light producing element and for generating an intensity signal representative of the intensity of at least one light producing element, and current control means for regulating the current to at least one of the light producing elements in response to said intensity signal to maintain constant intensity.
10. A microdensitometer system according to claim 9 wherein said illumination means further comprises illumination intensity control means for uniformly adjusting the intensity of each of light producing elements, said intensity control means including means for uniformly adjusting the current supplied to each of said light producing elements.
11. A microdensitometer system according to claim 1 wherein said illumination means includes means for maintaining said stable voltage reference irrespective of ambient temperature.
12. A microdensitometer system according to claim 1 wherein said alignment means includes an optical rail means, extending parallel to said imaging axis, for aligning said camera means along said imaging axis and baseplate means for supporting said optical rail means,
said camera means includes means for adjustably positioning said camera means along said optical rail means and
said illumination means is moveable in a direction transverse to said imaging axis and includes means for removably securing said illumination means to said baseplate means.
13. A microdensitometer system according to claim 12 wherein said means for removably securing said illumination means to said baseplate means includes a removable magnetic clamp.
This invention relates to a device for measuring two and three dimensional radiation dose distributions for radiation generating devices. Specifically, the invention relates to a system for recording the dose of radiation delivered to a target area and utilizing one or more recordings to measure radiation dose distributions for the tissue in and adjacent to the target area.
In the field of medicine, radiation is used for diagnostic, therapeutic and palliative treatment of patients. The conventional medical radiation sources used for these treatments include large fixed position machines as well as small, transportable radiation generating probes. The current state of the art treatment systems utilize computers to generate complex treatment plans that are difficult and sometimes impossible to verify using conventional measurement techniques such as ionization chambers which only record the dose at one point in space.
In order to be able to more precisely control the dosage and area of treatment, it is necessary to accurately measure and verify the dose distribution and precisely calibrate the device. This procedure is further complicated by fact that the radiation dosage is affected by the density of the material, the more dense the material the more radiation it will absorb. Therefore it is desirable to model the area to be irradiated in order to verify the proper radiation dose is being applied.
Accordingly, it is an object of this invention to provide an apparatus for measuring the dose distribution for radiation applied to a target area.
It is another object of the invention to provide an apparatus for measuring and recording the dose distribution and generating an image representing the dose distribution of radiation applied to a localized area.
It is another object of the invention to provide an apparatus for measuring and recording the dose distribution and generating an image representing the dose distribution of a miniaturized radiation source in a target area.
It is another object of the invention to provide an apparatus which is capable of measuring and recording the dose distribution and generating an image representing the dose distribution of a predefined radiation treatment plan applied to a medium having known density and radiation absorption characteristics.
It is yet another object of the invention to provide an apparatus which is capable of measuring and recording and generating a three dimensional image representing the dose distribution of radiation applied to a target area.
The invention relates to a phantom assembly and a microdensitometer. The phantom assembly supports radiation sensitive film in one or more predefined planes and optionally includes a channel for the insertion of a miniaturized radiation source. One preferred radiation sensitive film is radiochromic film. Radiochromic film is a special film used to measure the dose of ionizing radiation delivered to an area and does not require subsequent processing to develop the image. The optical density of the exposed film is proportional to the dose of ionizing radiation received. The radiochromic film is exposed by the radiation source. The radiochromic film is read by the microdensitometer and used to produce isodose contours and a three dimensional representation of the dose distribution.
The phantom assembly is preferably constructed of a tissue equivalent material and formed in substantially the same physical dimensions as the tissue being treated. The phantom assembly includes one or more locations where radiochromic film can be inserted for exposure. Preferably, several pieces of film, each parallel to a common plane but spaced apart at predetermined distances from the target area can be provided. Alternatively, the film can be oriented in three orthogonal planes for measuring the radiation dose applied to the target area in three dimensions.
The microdensitometer consists of a CCD Camera and a uniform light source connected by an optical rail. The CCD Camera is connected to a computer system which processes the image. The optical rail allows the camera to be moved with respect to the light source to change the magnification of the image while maintaining the camera in fixed alignment. The uniform light source includes a light box enclosing multiple light generating elements and a light diffusing element. The wavelength of the light generating elements is matched to the peak absorption wavelength of the exposed radiochromic film. The light generating elements and the diffusing element are designed to provide uniformity of better than 10% in the central area of the light box. The light generating elements are arranged in substantially annular arrays varying with intensity. The annular array with the highest intensity being adjacent the outer edges of the uniform light source. A current control circuit can be provided to adjust the light intensity and optimize the image for the dynamic range of the CCD camera. A photo-sensing element can also be provided to regulate the light intensity. The computer system acquires images from the camera and processes the images to produce isodose contours.
In order to obtain accurate profiles, the image is processed to compensate for various sources of error and noise. Dark image acquisition errors appear as differences in pixel values for the same level dark image. The system reads a pure black image and stores the dark value for each pixel and uses these dark values to compensate the image. The light image acquisition errors appear as differences in pixel values for the same level light image. They can also be caused by imperfections in the camera lens and non-uniformity of the light source. The system reads a light image and stores the individual light values for each pixel and uses these light values to compensate the image. Frame transfer errors occur when the CCD Camera takes a new image, the camera clocks in a blank image causing some image smearing. The system compensates for this error by first taking a short exposure and subtracting it from the second longer exposure. Scatter compensation error is caused by reflections from the surface of the camera lens, dust on the lens and the surface finish of the lens surfaces. To compensate for scatter error, an opaque object is imaged and a scatter compensation factor is generated as the average pixel value for the area of the opaque object divide by the average pixel value for the entire image. In addition, the system can scan same image of the film several times and take an average of the several scans.
The foregoing and other objects of this invention, the various features thereof, as well as the invention itself, may be more fully understood from the following description, when read together with the accompanying drawings in which:
FIG. 1 is a diagrammatic front view of a CCD Camera Microdensitometer in accordance with invention, the front door had been removed to facilitate comprehension;
FIG. 2 is a diagrammatic side view of the CCD Camera Microdensitometer of FIG. 1 in accordance with invention, the right side panel has been removed to facilitate comprehension;
FIG. 3 is section view of the light box along line 3--3 of FIG. 2;
FIG. 4 is a diagrammatic view of the circuit board showing the groupings of LEDS in accordance with the invention;
FIG. 5 is diagram showing the LED current control circuit; and
FIG. 6 is a representation of an image produced with the CCD Microdensitometer System in accordance with the invention.
The microdensitometer system provides a means for acquiring the images recorded on radiation sensitive film by reading them into a computer. The computer can then use conventional image processing techniques to produce isodose contours or images representing dose distribution in three dimensions.
As shown in FIGS. 1 and 2, the microdensitometer system includes a highly uniform light source 30 and a charge coupled device (CCD) camera 20 both coupled to an optical rail 40. The CCD camera 20 is directed along a principal axis 26 to the uniform light source 30. An imaging plane 28 is located between the CCD camera 20 and the uniform light source 30. Preferably, the imaging plane 28 coincides with the top surface of the uniform light source 30. A light tight enclosure 50 is also provided to block out ambient light that could affect the camera 20 readings. The CCD camera 20 is interconnected via a cable 62 to a computer system 60.
The light tight enclosure 50 includes a top wall 60, a bottom wall 62 and four lateral side walls, front 52, left 64, right 66, and rear 68. The front wall 52 is attached to the right side wall 66 by a hinge 54 and serves as a door. Adjacent the rear wall 68 is a rail 40 and a camera mounting element 22 that can be adjustably positioned along the rail 40. In one embodiment, the rail 40 is a cylindrical tube and the camera mounting element 22 includes a locking collar 24 that can be tightened around the tube 40. Either the rail 40 or the rear wall 68 adjacent the rail 40 can be provided with indicia 42 for indicating the distance from the camera 20 focal plane to the imaging plane 28 on the light source or indicating the relative magnification of the camera lens.
Preferably, the uniform light source 30 includes a locking element 38 for locking it in position in the light tight enclosure 50. This prevents any slight movement of the light source which would require recalibration of the system. In the preferred embodiment, the light tight enclosure 50 includes a steel baseplate 56 and the light source 30 includes a releasable magnetic clamp 38 which can engage the baseplate 56 and lock the light source 30 in place.
The radiation sensitive film can be either silver halide based films or radiochromic films. Radiochromic films are preferred because they provide several advantages over silver halide based films. Radiochromic films do not require subsequent processing to develop the image and they are not substantially affected by ambient light. In addition, the peak absorption wavelength of the radiochromic film can be selected based on the radiochromic dye used.
The light source 30 produces a specific wavelength of light that is highly uniform over a predefined area. Preferably, the wavelength is carefully chosen to match the peak absorption wavelength of the radiochromic film. In the preferred embodiment, the light source 30 uses GaAlAs LEDs to produce red light at a wavelength of 660 nanometers which is optimally matched to the radiochromic film selected. The preferred radiochromic film is GAFchromic film available from ISP Corporation of Wayne, N.J. The GaAlAs LEDs are type LN28WAL available from Panasonic Corporation of Japan.
Alternatively, the light source 30 can use Silicon Carbide LEDs to produce blue light at a wavelength of 470 nanometers which is optimally matched to a film having a peak absorption wavelength of 470 nanometers. In an alternative embodiment, blue light, such as that produced by the silicon carbide LEDs, can be used with film having a red peak absorption wavelength in order to extend the dynamic range of the measurement system.
FIG. 3 shows the highly uniform light source 30 which includes a light box 100 housing a plurality of light generating elements LED and a diffuser 120 arranged and configured to produce light uniformly over the top surface. The light box 100 includes a bottom wall, and four side walls. A circuit board 150 carrying an array of light emitting diodes (LEDs) LED is supported by channels in the side walls near the bottom of the light box. Preferably, the inside surfaces of the light box are made as shiny as possible to facilitate producing light uniformly. The light box also holds a diffuser 120 which further aids in providing light uniformly. In the preferred embodiment, the diffuser 120 includes one piece of frosted glass 122 and one piece of opal glass 124. The upper diffuser 122 is positioned as the top of the light box and the lower diffuser 124 is placed approximately half way between the upper diffuser 122 and the circuit board 150. The upper diffuser 122 also serves to support the radiochromic film for imaging.
As shown in FIG. 4, one preferred embodiment of the circuit board includes a rectangular matrix of sixty LEDs arranged in a planar, substantially annular array of ten groups of six LEDs 210--210. The current to each group of LEDs is chosen to precisely control the amount of light produced by each group. In this embodiment, three different levels of current are applied to three annular areas in order to produce a substantially uniform source of light. As shown in FIG. 5, this is accomplished by using three different current sensing resistors R2, R2' values in the circuits in each of the different annular areas. In the preferred embodiment, the current limiting resistor values are: 20 ohms for the outer most groups 201, 202, 203, and 204; 42.2 ohms for the middle groups 205, 206, 207, and 208 and 75.8 ohms for the inner most groups 209 and 210. Alternatively, the uniformity of the matrix of LEDs can be controlled by driving all the LEDs at the same current and properly selecting the spaces between adjacent LEDs to produce uniform intensity. In addition, the LEDs can be arranged in a substantially circular array and/or mounted in a cylindrical housing.
FIG. 4 also shows a photodiode D1 mounted on the circuit board 150 adjacent one of the LEDs LED55. The photodiode D1 is used in conjunction with a current control circuit to regulate the level of intensity of the LEDs. A potentiometer R1 can also be provide to permit manual adjustment of the relative intensity of the light source. By adjusting the potentiometer R1, the intensity can be adjusted to optimize the light source and resulting image for the dynamic range of the camera.
FIG. 5 shows a diagram of the circuit 200 for driving the LEDs. In order to produce a highly stable light source, the circuit includes a highly stable temperature compensated voltage reference 210. The circuit 200 also includes a current controlling circuit 220 which uses the photodiode D1 and the potentiometer R1. The photodiode D1 monitors the LED output and produces a signal representative of the LED intensity. The current control circuit detects any change in intensity and controls the current ensure that the light output is stable. The potentiometer R1 allows the LED output to be manually adjusted in order to optimize the light source 30 for the maximum dynamic range of the CCD camera 20.
FIG. 6 shows the resulting image produced by processing a single piece of radiochromic film. The dark lines are isodose contours. The image can also be rendered in color whereby the different colors represent predefined levels of absorbed radiation. Several such images from different planes can be combined using conventional computed image rendering techniques to produce a three dimensional representation of the radiation dose distribution.
In the preferred embodiment, the camera 20 is 242 by 375 pixel CCD camera capable of 16 bit resolution. The preferred camera is ST-6 available from the Santa Barbara Instrument Group of Santa Barbara, Calif. The computer is a desktop personal computer such as an IBM compatible personal computer or an APPLE Macintosh personal computer. Preferably, the computer is an Intel i486 based IBM compatible personal computer. The image processing software is MIRA available from Axiom Research, Inc. of Phoenix, Ariz.
In operation, the system is used to read an image recorded on a piece of radiochromic film. First the light source 30 is positioned under the camera 20 and locked in place. Next the camera 20 is adjusted to a position along the optical rail 40 for proper magnification and the camera lens is focused on the image plane 28. The system is then calibrated for dark imaging acquisition, light image acquisition, frame transfer compensation and scatter compensation. The film is placed on the upper surface of the light source 30. The camera reads the image and the computer processes the image to compensate for imaging errors determined during calibration.
Dark image acquisition error is compensated for by reading a dark image and recording dark level for each pixel. The computer system stores this compensation factor for each pixel and applies it by subtracting the corresponding compensation factor from each pixel value for the image being processed. This dark image error compensation factor will need to be recalibrated if either the CCD camera temperature or shutter speed changes. In the preferred embodiment, several dark images are read and the average over the several images is used to generate the dark image compensation factor.
Light image acquisition is used to compensate for non-uniformity of the light source 30, as well as non-uniformity of the lens and the CCD camera. A light image is read and the pixel values for the light image are recorded. The computer system stores this compensation factor for each pixel and applies it by dividing the corresponding pixel compensation factor by subsequent images pixel values. This error also varies with CCD camera temperature and shutter speed. In the preferred embodiment, the several light images are read and the average over the several images is used to generate the white compensation factor.
Frame transfer error is a known error in CCD cameras, occurring when a new image is read. Smearing occurs from the signal from pixels in a given column. To compensate for this, a short exposure of an image is taken and each pixel value subtracted from the corresponding pixel value of the second normal exposure of the same image which is much longer. The subtraction removes any frame transfer error and is thus completely compensated for.
Scattering errors occur due to the imperfections in the surface finish of the lens, reflections from the surfaces of the lens and from dust particles. To compensate for scattering error, a small opaque object is read and average pixel values for the opaque object and for the entire image are generated. A scatter compensation factor is calculated as the average for the opaque image divided by the average for the entire image. In subsequent images, the scatter compensation factor is multiplied by the average pixel value for the image and the resulting value is subtracted from each pixel in the image.
Image acquisition errors occur as random differences between successive reads of the same image. Depending upon the quality of the results required, several images can be taken and an average image used.
The system is also calibrated with respect to dose. This accomplished by imaging pieces of film exposed to known doses of radiation. The system produces a calibration curve by associating a given level of light intensity with a known dose of radiation. In this way subsequent images can calibrated and rendered in absolute dose.
In addition, the image must be calibrated with respect to distance in order to determine the number of pixels in the X and Y dimensions of the image. In the preferred embodiment, this is accomplished by placing a grid of known dimensions on the light source and calculating the number of pixels per unit distance.
The various compensation factors are stored in the computer for the particular setup. As long as the light source 30 is not moved or adjusted and the shutter speed is not changed, the system remains in calibration. Various pieces of radiochromic film can be placed on the light source and imaged. The raw image is then processed to compensate for the various errors discussed above to produce a precision image that accurately represents the radiation dose applied, such as FIG. 6. Several of these images from three orthogonal planes can be processed using conventional image rendering techniques in order to produce a three dimensional representation of the radiation dose. This information can be used by the medical practitioner to verify radiation treatments specified. Alternatively, this information can be used in any field where it is desirable to verify radiation dose delivery.
The invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are therefore to be considered in respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of the equivalency of the claims are therefore intended to be embraced therein.
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Los Alamos County Council approved the final design and construction of the White Rock Visitor Center Complex. The next step is to complete the design document, which will take about five months. Construction is expected to start in early spring 2011.
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7 p.m.
The Coaches: Redeemer's Pat Reece (0-0, 1st year); Northwest's Carl Majer (28-17, 5th year)
Last Meeting: Northwest 38-24 in 2011
All-Time Series: Northwest leads 4-0
Quick Fact: Northwest has scored at least 33 points in all four meetings.
Scouting Redeemer: Reece takes over and has some passing weapons at his disposal with QB Jimmy Strickland and pass catchers Thomas Cosgrove and Eric Kerr. The Royals, though, really need to run the ball with consistency. And block much, much better.
Scouting Northwest: Northwest running back Tony Politz had a career-high 244 yards in last year's victory over Redeemer. The Rangers' 352 yards on the ground were also a season high. The passing offense will be a work in progress. The parts are there, but some assembly is required.
What To Expect: Running Politz last season worked, so don't expect Northwest to deviate too much from that philosophy. It should be good enough for a victory.
-- John Erzar


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Looking in your eyes is like a mirror, have to face my fears
from Jay Z – Jay Z Blue Lyrics on Genius
Every time he sees his daughter he sees himself in her, and she holds a mirror up to him and makes him assess himself. While earlier he indicates that he sees his own past demons in his fatherhood, he's now saying he has to deal with them.
To help improve the quality of the lyrics, visit Jay Z – Jay Z Blue Lyrics and leave a suggestion at the bottom of the page


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Hartley works to tame the 'Lion'
Story | Apr 29, 2014 | 2:41 PM
Hartley works to tame the 'Lion'
Story | Apr 29, 2014 | 2:41 PM
Op-Ed: Ending conversion therapy for LGBT youth
Story | May 2, 2014 | 12:27 PM
Kirk Murphy was 5 years old when his mother took him to see a therapist. She was concerned because he liked to play with girl's toys. The therapist assured his mother that he could help Kirk act more like a boy. After 10 months of treatment that...
In Theory: Is 'radicalization' child abuse?
Story | Mar 7, 2014 | 11:43 AM
The mayor of London wrote in a March 2 column in the Daily Telegraph that Muslim children who are at risk of radicalization by their parents are victims of child abuse and should be removed from their homes. Mayor Boris Johnson says that such a move...
Year in Review: A year of tragedy and triumph
Story | Dec 28, 2012 | 10:40 PM


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Strictly Salsa
A birthday cake for a salsa and strictly come dancing loving couple.
By far the most complicated figures I've made.
I do like the glitter ball effect onthe top of the cake though.
Sparkle, sparkle and glitter!
Tags: birthday black pink silver cake chocolate salsa couple dancing strictly


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Important Safety Information
INTUNIV is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents aged 6 to 17. Efficacy was established in two controlled clinical trials (8 and 9 weeks in duration). The physician electing to use INTUNIV for extended periods should periodically reevaluate its long-term usefulness for the individual patient.
INTUNIV should not be used in patients with a history of hypersensitivity to guanfacine or any of its inactive ingredients or by patients taking other products containing guanfacine
Hypotension, bradycardia, and syncope were observed in clinical trials. Use INTUNIV with caution in treating patients who have experienced hypotension, bradycardia, heart block, or syncope, or who may have a condition that predisposes them to syncope; are treated concomitantly with antihypertensives or other drugs that can reduce blood pressure or heart rate or increase the risk of syncope. Heart rate and blood pressure should be measured prior to initiation of therapy, following dose increases, and periodically while on therapy. Patients should be advised to avoid becoming dehydrated or overheated.
Sedation and somnolence were commonly observed in clinical trials. The potential for additive sedative effects with CNS depressant drugs should be considered. Patients should be cautioned against operating heavy equipment or driving until they know how they respond to INTUNIV.
Common adverse reactions in patients taking INTUNIV that may be dose-related over the range of 1 to 4 mg/day include somnolence, sedation, abdominal pain, dizziness, hypotension/decreased blood pressure, dry mouth, and constipation.
About ADHD
ADHD is one of the most common psychiatric disorders in children and
adolescents. Worldwide prevalence of ADHD is estima
|SOURCE Shire Plc
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Journal Articles
Small Increases To Employer Premiums Could Shift Millions Of People To The Exchanges And Add Billions To Federal Outlays
2013; 32 (9): 1531-1537
The Affordable Care Act will expand insurance coverage to more than twenty-five million Americans, partly through subsidized private insurance available from newly created health insurance exchanges for people with incomes of 133-400 percent of the federal poverty level. The act will alter the financial incentive structure for employers and influence their decisions on whether or not to offer their employees coverage. These decisions, in turn, will affect federal outlays and revenues through several mechanisms. We model the sensitivity of federal costs for the insurance exchange coverage provision of the Affordable Care Act using the nationally representative Medical Expenditure Panel Survey data set. We assess revenues and subsidy outlays for premiums and cost sharing for individuals purchasing private insurance through exchanges. Our findings show that changing theoretical premium contribution levels by just $100 could induce 2.25 million individuals to transition to exchanges and increase federal outlays by $6.7 billion. Policy makers and analysts should pay especially careful attention to participation rates as the act's implementation continues.
View details for DOI 10.1377/hlthaff.2013.0522
View details for Web of Science ID 000324681500004
View details for PubMedID 24019356
Targeting the BH3-interacting domain death agonist to develop mechanistically unique antidepressants
2012; 17 (8): 770-780
The BH3-interacting domain death agonist (Bid) is a pro-apoptotic member of the B-cell lymphoma-2 (Bcl-2) protein family. Previous studies have shown that stress reduces levels of Bcl-2 in brain regions implicated in the pathophysiology of mood disorders, whereas antidepressants and mood stabilizers increase Bcl-2 levels. The Bcl-2 protein family has an essential role in cellular resilience as well as synaptic and neuronal plasticity and may influence mood and affective behaviors. This study inhibited Bid in mice using two pharmacological antagonists (BI-11A7 and BI-2A7); the selective serotonin reuptake inhibitor citalopram was used as a positive control. These agents were studied in several well-known rodent models of depression-the forced swim test (FST), the tail suspension test (TST), and the learned helplessness (LH) paradigm-as well as in the female urine sniffing test (FUST), a measure of sex-related reward-seeking behavior. Citalopram and BI-11A7 both significantly reduced immobility time in the FST and TST and attenuated escape latencies in mice that underwent the LH paradigm. In the FUST, both agents significantly improved duration of female urine sniffing in mice that had developed helplessness. LH induction increased the activation of apoptosis-inducing factor (AIF), a caspase-independent cell death constituent activated by Bid, and mitochondrial AIF expression was attenuated by chronic BI-11A7 infusion. Taken together, the results suggest that functional perturbation of apoptotic proteins such as Bid and, alternatively, enhancement of Bcl-2 function, is a putative strategy for developing novel therapeutics for mood disorders.
View details for DOI 10.1038/mp.2011.77
View details for Web of Science ID 000306760600002
View details for PubMedID 21727899
Acute D-serine treatment produces antidepressant-like effects in rodents
2012; 15 (8): 1135-1148
Research suggests that dysfunctional glutamatergic signalling may contribute to depression, a debilitating mood disorder affecting millions of individuals worldwide. Ketamine, a N-methyl-D-aspartate (NMDA) receptor antagonist, exerts rapid antidepressant effects in approximately 70% of patients. Glutamate evokes the release of D-serine from astrocytes and neurons, which then acts as a co-agonist and binds at the glycine site on the NR1 subunit of NMDA receptors. Several studies have implicated glial deficits as one of the underlying facets of the neurobiology of depression. The present study tested the hypothesis that D-serine modulates behaviours related to depression. The behavioural effects of a single, acute D-serine administration were examined in several rodent tests of antidepressant-like effects, including the forced swim test (FST), the female urine sniffing test (FUST) following serotonin depletion, and the learned helplessness (LH) paradigm. D-serine significantly reduced immobility in the FST without affecting general motor function. Both D-serine and ketamine significantly rescued sexual reward-seeking deficits caused by serotonin depletion in the FUST. Finally, D-serine reversed LH behaviour, as measured by escape latency, number of escapes, and percentage of mice developing LH. Mice lacking NR1 expression in forebrain excitatory neurons exhibited a depression-like phenotype in the same behavioural tests, and did not respond to D-serine treatment. These findings suggest that D-serine produces antidepressant-like effects and support the notion of complex glutamatergic dysfunction in depression. It is unclear whether D-serine has a convergent influence on downstream synaptic plasticity cascades that may yield a similar therapeutic profile to NMDA antagonists like ketamine.
View details for DOI 10.1017/S1461145711001386
View details for Web of Science ID 000307188000011
View details for PubMedID 21906419
The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications
2012; 2
Glutamatergic signaling through N-methyl-D-aspartate receptors (NMDARs) is required for synaptic plasticity. Disruptions in glutamatergic signaling are proposed to contribute to the behavioral and cognitive deficits observed in schizophrenia (SZ). One possible source of compromised glutamatergic function in SZ is decreased surface expression of GluN2B-containing NMDARs. STEP(61) is a brain-enriched protein tyrosine phosphatase that dephosphorylates a regulatory tyrosine on GluN2B, thereby promoting its internalization. Here, we report that STEP(61) levels are significantly higher in the postmortem anterior cingulate cortex and dorsolateral prefrontal cortex of SZ patients, as well as in mice treated with the psychotomimetics MK-801 and phencyclidine (PCP). Accumulation of STEP(61) after MK-801 treatment is due to a disruption in the ubiquitin proteasome system that normally degrades STEP(61). STEP knockout mice are less sensitive to both the locomotor and cognitive effects of acute and chronic administration of PCP, supporting the functional relevance of increased STEP(61) levels in SZ. In addition, chronic treatment of mice with both typical and atypical antipsychotic medications results in a protein kinase A-mediated phosphorylation and inactivation of STEP(61) and, consequently, increased surface expression of GluN1/GluN2B receptors. Taken together, our findings suggest that STEP(61) accumulation may contribute to the pathophysiology of SZ. Moreover, we show a mechanistic link between neuroleptic treatment, STEP(61) inactivation and increased surface expression of NMDARs, consistent with the glutamate hypothesis of SZ.
View details for DOI 10.1038/tp.2012.63
View details for Web of Science ID 000306221300009
View details for PubMedID 22781170
The effects of chronic treatment with mood stabilizers on the rat hippocampal post-synaptic density proteome
2011; 119 (3): 617-629
Bipolar disorder is a devastating illness that is marked by recurrent episodes of mania and depression. There is growing evidence that the disease is correlated with disruptions in synaptic plasticity cascades involved in cognition and mood regulation. Alleviating the symptoms of bipolar disorder involves chronic treatment with mood stabilizers like lithium or valproate. These two structurally dissimilar drugs are known to alter prominent signaling cascades in the hippocampus, but their effects on the post-synaptic density complex remain undefined. In this work, we utilized mass spectrometry for quantitative profiling of the rat hippocampal post-synaptic proteome to investigate the effects of chronic mood stabilizer treatment. Our data show that in response to chronic treatment of mood stabilizers there were not gross qualitative changes but rather subtle quantitative perturbations in post-synaptic density proteome linked to several key signaling pathways. Our data specifically support the changes in actin dynamics on valproate treatment. Using label-free quantification methods, we report that lithium and valproate significantly altered the abundance of 21 and 43 proteins, respectively. Seven proteins were affected similarly by both lithium and valproate: Ank3, glutamate receptor 3, dynein heavy chain 1, and four isoforms of the 14-3-3 family. Immunoblotting the same samples confirmed the changes in Ank3 and glutamate receptor 3 abundance. Our findings support the hypotheses that BPD is a synaptic disorder and that mood stabilizers modulate the protein signaling complex in the hippocampal post-synaptic density.
View details for DOI 10.1111/j.1471-4159.2011.07424.x
View details for Web of Science ID 000297019300017
View details for PubMedID 21838781
Bax inhibitor 1, a modulator of calcium homeostasis, confers affective resilience
2011; 1403: 19-27
The endoplasmic reticulum (ER) is a critical site for intracellular calcium storage as well as protein synthesis, folding, and trafficking. Disruption of these processes is gaining support for contributing to heritable vulnerability of certain diseases. Here, we investigated Bax inhibitor 1 (BI-1), an anti-apoptotic protein that primarily resides in the ER and associates with B-cell lymphoma 2 (Bcl-2) and Bcl-XL, as an affective resiliency factor through its modulation of calcium homeostasis. We found that transgenic (TG) mice with BI-1 reinforced expression, via the neuronal specific enolase promoter, showed protection against the learned helplessness (LH) paradigm, an animal model to test stress coping. TG mice were also protected against anhedonia following both serotonin and catecholamine depletion as measured in two different models, the female urine sniffing test and the saccharine preference test. In addition, we used primary mouse cortical cultures to explore the ability of BI-1 to influence calcium homeostasis under basal conditions and also following challenge with thapsigargin (THPS), an inhibitor of sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) that disrupts calcium homeostasis. TG neurons showed decreased basal cytosolic calcium levels and decreased Ca(2+) cytosolic accumulation following challenge with THPS as compared to WT neuronal cultures. Together, these data suggest that BI-1, through its actions on calcium homeostasis, may confer affective resiliency in multiple animal models of depression and anhedonia.
View details for DOI 10.1016/j.brainres.2011.05.067
View details for Web of Science ID 000293156800003
View details for PubMedID 21718971
Lithium treatment attenuates muscarinic M-1 receptor dysfunction
2011; 13 (3): 238-249
Altered muscarinic acetylcholine receptor levels and receptor-coupled signaling processes have been reported in mood disorders. M(1) , one of five muscarinic receptor subtypes, couples to the phospholipase C/protein kinase C and extracellular signal-regulated kinase (ERK) pathways. Mood stabilizers regulate these pathways. MicroRNAs (miRNAs) are small noncoding RNAs that suppress translation in a sequence-selective manner. Lithium downregulates several miRNAs, including let-7b and let-7c. One predicted target of let-7b and let-7c is the M(1) receptor. We hypothesized that miRNAs regulate M(1) receptor translation, and that disrupted M(1) expression leads to aberrant behaviors and disrupted downstream signaling pathways that are rescued by lithium treatment.The effects of miRNAs and chronic treatment with mood stabilizers on M(1) levels were tested in primary cultures and in rat frontal cortex. Effects of M(1) ablation and chronic treatment with mood stabilizers on several signaling cascades and M(1) -modulated behaviors were examined in wild-type and M(1) knockout mice. Results:? Let-7b, but not let-7c, negatively regulated M(1) levels. Chronic treatment with lithium, but not valproate, increased M(1) levels in the rat cortex. M(1) knockout mice exhibit ERK pathway deficits and behavioral hyperactivity; chronic treatment with lithium attenuated these deficits and hyperactivity.Lithium treatment can affect M(1) receptor function through intracellular signaling enhancement and, in situations without M(1) ablation, concomitant receptor upregulation via mechanisms involving miRNAs. Muscarinic dysfunction may contribute to mood disorders, while M(1) receptors and the downstream ERK pathway may serve as potential therapeutic targets for alleviating manic symptoms such as psychomotor hyperactivity.
View details for DOI 10.1111/j.1399-5618.2011.00915.x
View details for Web of Science ID 000292666000003
View details for PubMedID 21676127
Cellular mechanisms underlying affective resiliency: The role of glucocorticoid receptor- and mitochondrially-mediated plasticity
2009; 1293: 76-84
Bipolar disorder (BPD) is a devastating psychiatric illness marked by recurrent episodes of mania and depression. While the underlying pathophysiology of BPD remains elusive, an abnormal hypothalamic-pituitary-adrenal (HPA) axis and dysfunctional glucocorticoid receptor (GR) signaling are considered hallmarks. This review will examine how targeting resiliency signaling cascades at the cellular level may serve as a mechanism to treat BPD. Here, cellular resiliency is defined as the ability of a cell to adapt to an insult or stressor. Such resiliency at the cellular level could confer resiliency at the systems level and, ultimately, help individuals to cope with stressors or recover from depressive or manic states. This review will focus on four molecular targets of mood stabilizers that are known to play integral roles in these cellular resiliency signaling pathways: (1) B-cell CLL/lymphoma 2 (Bcl-2), (2) Bcl-2-associated athanogene (BAG-1), (3) glucocorticoid receptors (GRs), and (4) 51 kDa FK506-binding protein (FKBP5). These targets have emerged from neurobiological and human genetic studies and employ mechanisms that modulate GR function or promote anti-apoptotic processes critical to affective resilience. Future research should focus on elucidating sustainable treatments that target resiliency factors-such as BAG-1 or FKBP5-which could ultimately be used to treat individuals suffering from BPD and prevent relapses in afflicted individuals. Further identification of resiliency and susceptibility factors will also be vital. Ultimately, these developments would allow for the treatment of susceptible individuals prior to the development of BPD.
View details for DOI 10.1016/j.brainres.2009.06.103
View details for Web of Science ID 000270865600008
View details for PubMedID 19595676
MicroRNAs in Mental Health: From Biological Underpinnings to Potential Therapies
2009; 11 (3): 173-182
Psychiatric illnesses are disabling disorders with poorly understood underlying pathophysiologies. However, it is becoming increasingly evident that these illnesses result from disruptions across whole cellular networks rather than any particular monoamine system. Recent evidence continues to support the hypothesis that these illnesses arise from impairments in cellular plasticity cascades, which lead to aberrant information processing in the circuits that regulate mood, cognition, and neurovegetative functions (sleep, appetite, energy, etc.). As a result, many have begun to consider future therapies that would be capable of affecting global changes in cellular plasticity to restore appropriate synaptic function and neuronal connectivity. MicroRNAs (miRNAs) are non-coding RNAs that can repress the gene translation of hundreds of their targets and are therefore well-positioned to target a multitude of cellular mechanisms. Here, we review some properties of miRNAs and show they are altered by stress, glucocorticoids, mood stabilizers, and in a particular psychiatric disorder, schizophrenia. While this field is still in its infancy, we consider their potential for regulating behavioral phenotypes and targeting key predicted signaling cascades that are implicated in psychiatric illness. Clearly, considerable research is required to better determine any therapeutic potential of targeting miRNAs; however, these agents may provide the next generation of effective therapies for psychiatric illnesses.
View details for DOI 10.1007/s12017-009-8070-5
View details for Web of Science ID 000270284500005
View details for PubMedID 19544012
Reverse translational strategies for developing animal models of bipolar disorder
2009; 2 (5-6): 238-245
Bipolar disorder (BD) affects a significant portion of the population of the world, yet there has been limited success in developing novel treatments for the disorder. One of the major reasons for this dearth is the absence of suitable animal models for BD. Traditionally, animal models of human phenomena have been evaluated based on similarity to the human syndrome, response to appropriately corresponding medications, and the degree to which a model supports a common mechanistic theory between the human disorder and the model itself. The following review emphasizes the use of 'reverse translation', drawing on patient-based findings to develop suitable animal models for BD. We highlight some examples of this strategy, emphasizing their construct validity as a starting point. These studies have produced informative models that have altered the expression of genes/pathways implicated in BD, including the point mutation D181A of mouse mitochondrial DNA polymerase (POLG), glutamate receptor 6 (GluR6), Clock, extracellular regulated kinase 1 (ERK1), glycogen synthase kinase-3beta (GSK-3beta), B-cell lymphoma 2 (Bcl-2) and Bcl-2-associated athanogene (BAG-1). These studies demonstrate that this method is useful, viable and deserves attention in new efforts to generate animal models of BD.
View details for DOI 10.1242/dmm.001628
View details for Web of Science ID 000268455300010
View details for PubMedID 19407332
Animal models of suicide-trait-related behaviors
2009; 30 (4): 165-173
Although antidepressants are moderately effective in treating major depressive disorder (MDD), concerns have arisen that selective serotonin-reuptake inhibitors (SSRIs) are associated with suicidal thinking and behavior, especially in children, adolescents and young adults. Almost no experimental research in model systems has considered the mechanisms by which SSRIs might be associated with this potential side effect in some susceptible individuals. Suicide is a complex behavior and impossible to fully reproduce in an animal model. However, by investigating traits that show strong cross-species parallels in addition to associations with suicide in humans, animal models might elucidate the mechanisms by which SSRIs are associated with suicidal thinking and behavior. Traits linked with suicide in humans that can be successfully modeled in rodents include aggression, impulsivity, irritability and hopelessness/helplessness. Modeling these relevant traits in animals can help to clarify the impact of SSRIs on these traits, suggesting avenues for reducing suicide risk in this vulnerable population.
View details for DOI 10.1016/j.tips.2009.01.004
View details for Web of Science ID 000265331100001
View details for PubMedID 19269045
The neurotrophic and neuroprotective effects of psychotropic agents.
Dialogues in clinical neuroscience
2009; 11 (3): 333-348
Accumulating evidence suggests that psychotropic agents such as mood stabilizers, antidepressants, and antipsychotics realize their neurotrophic/neuroprotective effects by activating the mitogen activated protein kinase/extracellular signal-related kinase, PI3-kinase, and wingless/glycogen synthase kinase (GSK) 3 signaling pathways. These agents also upregulate the expression of trophic/protective molecules such as brain-derived neurotrophic factor, nerve growth factor, B-cell lymphoma 2, serine-threonine kinase, and Bcl-2 associated athanogene 1, and inactivate proapoptotic molecules such as GSK-3. They also promote neurogenesis and are protective in models of neurodegenerative diseases and ischemia. Most if not all, of this evidence was collected from animal studies that used clinically relevant treatment regimens. Furthermore, human imaging studies have found that these agents increase the volume and density of brain tissue, as well as levels of N-acetyl aspartate and glutamate in selected brain regions. Taken together, these data suggest that the neurotrophic/neuroprotective effects of these agents have broad therapeutic potential in the treatment; not only of mood disorders and schizophrenia, but also neurodegenerative diseases and ischemia.
View details for PubMedID 19877500


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Region 2: Texas Medicaid 1115 Waiver
On behalf of the Region 2 anchor team, CONGRATULATIONS to all performing providers who completed their April DY4 DSRIP reporting! Kudos to the work regional performing providers have done to meet DSRIP project metrics and milestones which were designed to transform healthcare delivery in Texas as well as optimize health system performance through three dimensions, which we call the "Triple Aim:" 1) improving the patient experience of care, including quality and satisfaction; 2) improving the health of populations; and, 3) reducing the per capita cost of health care. Please take a few minutes to stop and celebrate your accomplishments, and use these significant results to motivate you and your colleagues to push forward to make even more substantial impact during the remainder of the current waiver period. ~ Craig Kovacevich
Important Dates
May 20, 2015, 5:00pm–Due date for IGT Entities to approve and comment on their affiliated providers' April reported progress on metrics using the "IGT Info" tab for each project (please do not use this tab to identify technical errors entered in the reporting system)
June 10, 2015–HHSC and CMS will complete their review and approval of April reports or have NMI requests
July 2, 2015, 11:59pm–Responses to NMI due
July 8, 2015–IGT due for April reporting
July 21, 2015–April reporting DY4 DSRIP payments for transferring hospitals and top 14 IGT Entities
July 31, 2015–April reporting DY2 and DY3 DSRIP payments processed for all providers and DY4 DSRIP payments for remaining providers that were not paid on July 21, 2015. *Note: there are separate transactions for each payment for each DY
August 7, 2015–HHSC and CMS will approve or deny the additional information submitted for NMI requests
Important Announcements
Waiver Renewal Planning
HHSC will post a draft of the Waiver Extension/Renewal request for public review in June 2015, and will hold public meetings throughout Texas during July. One of these meetings will be held in Houston, and the Anchor Office encourages Region 2 performing providers and stakeholders to consider attending in person if possible. As soon as HHSC publishes the public meeting schedule, the Anchor Office will send a regional announcement, and the complete schedule will be posted on both the HHSC and regional websites.
The Clinical Champions workgroup, in coordination with HHSC leadership and staff, is developing a process for DSRIP performing providers to demonstrate the benefits and early successes of some of the strongest DSRIP projects through peer assessment reviews. As soon as more information is available, it will be shared with the region. The Anchor Office will be ready to assist providers as needed since there will be a quick turnaround time (end of May) to get assessments completed and returned to HHSC.


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Pebble Dragon, Tympanocryptis cephalus
Jaurdi, Western Australia
An Armoured Pricklenape (Acanthosaurus agama), also known as the Peninsular Horned Tree Lizard. This agamid lizard is found in China (Hainan), Myanmar (= Burma), S Thailand, the Malaysian peninsula, Indonesia (Sumatra), Palau Pinang and Pulau Tioman.
Photo © Blepharopsis / Igor Siwanowicz
bearded dragon on Flickr.
"Fan-throated Lizard" (Sitana ponticeriana)
…a species of agamid lizard that occurs in India, Sri Lanka and parts of Pakistan. Fan-throated lizards typically inhabit sandy coastal areas and open areas in forests and scrublands. They are primarily terrestrial but are known to inhabit trees as well. Like some other lizards S. ponticeriana possesses a brightly colored dewlap, which is used primarily in courtship but can also be used in communication and defense.
Animalia-Chordata-Reptilia-Lacertilia-Iguania-Agamidae-Agaminae-Sitana-S. ponticeriana
Images: J.M. Garg and Dr. Caesar Photography
Hump-nosed Lizard (Lyriocephalus scutatus)
also known as the Lyreshead Lizard, the hump-nosed lizard is a species of Agamid lizard native to Sri Lanka. It gets its name from a small knob on the top of its nose which i can only guess is used in display. They also have a dewlap under their chins to deter predators. They are often found in wet forests where they do lizard things….


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Dog in Mexico kills toddler
More News from Associated Press
MEXICO CITY – Mexico City prosecutors said they are considering criminal charges against the owner of a dog that dragged a toddler off the street and killed him.
Prosecutors said the boy aged 1 year, 8 months was walking down a street with his mother on the city's southern outskirts when a boxer stuck its head through a fence, seized the child and pulled it into the yard where there were two other boxers and a pit bull. Together, they killed the child, though the dog owner tried to pull the boy away.
Prosecutors said late Tuesday the dogs have been taken to a city animal-control facility to be examined to determine whether they represent a continuing danger. They say the owner might face charges of criminal negligence.
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4191 GLUT + modules.conf problems
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Join Date: Dec 2002
Posts: 2
4191 GLUT + modules.conf problems
I have two separate problems with the new drivers.
Most annoyingly, the nvidia module does not load automatically on boot. This has always worked fine before, and works when I revert back to the older drivers. When 4191 is installed I have the following in my modules.conf
alias char-major-195 nvidia
This is the same as how the old drivers use it except obviously the driver name is NVdriver. I don't even know how to start looking for problems here. Does anyone have a link on how modules.conf actually works? I mean what makes the system know it should load the module 'nvidia'? I know I can just add an insmod somewhere in my boot, but I'd like to know how to do it properly
My other problem is with GLUT. After installing 4191 some apps, like celestia and billards-gl failed with a 'GLXBadRenderRequest'. The apps are linked to libGLU.so.1 which on my system is from a package named xlibmesa3. The same package and apps work fine with the older drivers though.
So I'm having to use 3123 at the moment, which seems a little slower (the new 2D work seems to go quite well on mine).
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What features does Skype on my Blu-ray player support?
The exact features may vary from manufacturer to manufacturer, but most products will support the following features:
- Free voice and video Skype-to-Skype calls
- Calling mobiles and landlines at great Skype rates using your Skype Credit - you can buy Skype Credit from your Skype account on your computer, phone or tablet.
- Retrieving your Skype voice messages
- Participation in a voice group call with up to 24 other people
- Some products will support HD video calling
Be aware that you can make voice calls to anyone using Skype, but you will only be able to make video calls to people who are using Skype 5.0 for Windows or higher, or Skype 5.0 for Mac.
For further support, you can contact the Blu-ray player manufacturer.


text: Does anyone know why I cannot get the infinite Kleos cheat to work? When they say the title screen, do they mean where it says 300 march to glory or after you press start and you can select to continue to load etc? Also are they referring to the D-pad or the analog stick? I tried all different combinations and I cannot figure it out. Thanks!!!


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I love this scripture so much that everytime i read it i get a different understanding. To know i have life o man no wonder am a life giving spirit.
Colossians 1:27 - Christ IN KIRSTIN IS GLORY......says it all...
its a transforming scripture one can ever read
1 John 4:4 ....greater is He that is in me, than He that is in the world...
Yes I have
I have....James 5:16b
Wow I enternal life is in me! PRAISE GOD!
2 Cor 4:16-18: "So we are not giving up. How could we! Even though on the outside it often looks like things are falling apart on us, on the inside, where God is making new life, not a day goes by without his unfolding grace. These hard times are small potatoes compared to the coming good times, the lavish celebration prepared for us......." I say what I believe not vice versa, Praise God!


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Masonic Traveler on AmazonPosted by GregS
Apr 19
I am just in from a week away and happened to take a peek at Amazon, and to my amazement they have already picked up and made the book available for purchase!
So, if your an Amazon shopper, you can get your copy of Masonic Traveler – Essays and Commentary now!
Or, you can order them through my links here on this site as I've just done the foot work to determine the fulfillment and handling. I'm placing an order tonight for my first batch of 50 copies to send out. If your interested, you can order your copy here or off of the main page!
Thanks for the support!


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Friday's standings are as follows! TEAM DONATIONS AMOUNT Team Borepatch 14 630 Team HBC Concealment 8 618 Team JayG 13 405 Team Old NFO 7 350 Team USA Karate 6 335 Team Ambulance Driver 4 255 Team McThag 5 215 Team Happy Medic 2 200 Team Coykendall 3 110 Team Brosius 2 […]View Post
A wild weekend for fundraising!
Our fundraising teams have kilted up and got the word out! Here are the standings as of 12 noon central time Monday September 8th 2014! Team Donors Totals Team HBC Concealment 7 578 Team Borepatch 12 570 Undesignated 6 285 Team Old NFO 6 250 Team JayG 5 195 Team McThag 4 195 Team […]View Post
Fundraising Team Update!
It's Friday, which means another update on the Fundraising Competition here at Kilted to Kick Cancer. We appreciate everyone's help this year in spreading the word about Prostate Cancer. Here are the standings as of 11 AM CST Friday September 5th 2014! Team Donations Totals Team HBC Concealment 1 500 Undesignated 4 […]View Post
Fundraising Competition Update!
We're working on a way for you team leaders to see your team's progress in real time but in the meantime here are the standings as of 9:19 AM (central) Sept 3rd! 500.00 Team HBC Concealment 120.00 Undesignated 100.00 Team Ambulance Driver 75.00 Team McThag 60.00 Team Borepatch 60.00 Team Coykendall 50.00 Team Brosius […]View Post
How to Register a Fund Raising Team for KTKC 2014
Some folks have sent emails asking about joining KTKC on the website and if that also includes adding a Fundraising team. No. Registering on our website (And you should) adds you as a member of the Kilted Army. Signing up for our newsletter (Which you should also do) will keep you in the […]View Post


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My Story
by Ron Marchant
The family biography of Ronald Victor Marchant. Ron was born and raised in Brighton. The book chronicles his family life, experience as a engineer, his involvement in WWII and his legendary humour and wit.
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Ticonderoga posted victories in Champlain Valley Athletic Conference cross country action Sept. 22.
The Sentinels beat AuSable Valley, 25-34, and Lake Placid, 15-50. in the girls meet. They lost to Saranac Lake, 19-36.
Katie Karkoski led Ti, finishing fifth overall.
Tabitha Taylor was eighth for the winners, followed by Becky Barber ninth, Hannah Herbst 11th, Brittany Holt 13th and Alaina Bevilacqua 14th.
In the boys race Ticonderoga beat AuSable Valley, 27-28, Lake Placid, 21-35, and Saranac Lake, 15-50.
Jay Berube won the race for the Sentinels.
Josh Cook was third for Ti, followed by Ben Karkoski ninth, Kevin Densmore 11th and Mark Barber 13th.
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County roads safer in '08 than '07
Cities rank dangerous in some areas, according to state's safety statistics
Ventura County roads were generally safer in 2008 than the year before, although several cities ranked among the most dangerous in some traffic categories, according to new statistics from the state Office of Traffic Safety.
Overall, 5,354 people were injured or killed in 2008 traffic accidents in Ventura County, about 5 percent fewer than in 2007, according to data the office released last week. Traffic injuries and deaths declined 6.7 percent statewide during the same period, said Chris Cochran, a spokesman for the Office of Traffic Safety. Statistics for 2009 are not yet available.
More than 98 percent of the traffic casualties tallied in the data were injuries, not deaths. According to the Ventura County Medical Examiner-Coroner's Office, 77 people died in traffic accidents in Ventura County in 2008, compared with 83 in 2007.
The drop came as the average number of miles traveled daily by motorists in Ventura County declined by only 0.6 percent in 2008.
Oxnard registered some of the most dramatic improvements in traffic safety from 2007 to 2008, but its roads remained among the most dangerous for California cities of a similar size.
Total injuries and deaths in Oxnard dropped by 170, to 1,394 in 2008, but that was still the second highest among 55 cities in its population category, according to the traffic safety office's rankings.
The number of alcohol-involved accidents in Oxnard dropped by 32, to 197 in 2008, but that also was the second highest among similar-size cities.
The rankings did include one bright spot for Oxnard: For motorcycle crashes, the city was the seventh safest among the 55.
Oxnard Police Chief John Crombach attributed the drops in overall and alcohol-related accidents to aggressive enforcement, community education, and responsible beverage-service training for those with alcohol licenses. He said the 2009 statistics should show a further reduction in Oxnard accidents.
Crombach said he doesn't know why Oxnard has more traffic problems than most cities of a similar size. He said it should be judged on its progress, not on rankings. "If we're making progress, then we're doing something right," he said.
Thousand Oaks' roads were generally safer than average when compared with similar-size cities in 2008, but they were among the most dangerous for bicyclists.
Injury accidents involving bicyclists in Thousand Oaks climbed from 45 in 2007 to 75 in 2008, the fourth highest among the 55 cities.
In the majority of the 2008 collisions between cars and bicycles, however, the cyclists were deemed at fault because they were riding against traffic or making unsafe turns, said Thousand Oaks Police Chief Jeff Matson. Impatient drivers who don't pay enough attention to cyclists were also part of the problem, he said.
Matson said efforts to ease the problem over the past year have helped. As of Dec. 30, there were 69 bicyclists injured or killed this year in Thousand Oaks, he said. The efforts included adding markers to show bicyclists the direction they should ride, a public education campaign, and citations for wrong-way cyclists, Matson said.
Overall, Thousand Oaks ranked 18th in traffic safety among the 55 cities.
Santa Paula's 10 motorcycle injuries and fatalities in 2008 ranked second among the 97 cities in its population group. One of Santa Paula's best categories was DUI arrests; only 25 of the cities had more.
In 11 of 15 categories, Simi Valley roads ranked among the 15 safest of the 55 cities. The number of people killed or injured in traffic accidents in the city dropped almost 14 percent, from 477 in 2007 to 412 in 2008.
Simi Valley Police Chief Mike Lewis said the city's accident statistics have been trending downward for five years. He attributed the improvements to increased police focus on problem intersections and public education.
Simi Valley's worst category was injuries involving bicyclists younger than 15. Police worked to raise public awareness about the issue, and the number appeared down in 2009, Lewis said.
"It's not a chronic problem," he said.
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by Bryce Covert Posted on May 20, 2015
More than 1,600 families, including 2,700 children, will lose their benefits.
by Casey Quinlan Posted on May 20, 2015
Texas' enhancements to their pre-K program may be far from perfect but they are a step forward for a program that has lost funding in recent years.
by Lauren C. Williams Posted on May 20, 2015
Renz's hiring makes her the first female executive to directly report to Amazon CEO Jeff Bezos.
Yale University's former president, Richard C. Levin, received a handsome retirement benefit after leaving the university.
Los Angeles voted to move forward with a wage hike to $15 an hour by 2020.
by Alice Ollstein Posted on May 20, 2015
Bernie Sanders (I-VT) wants to see a "revolution" in higher education funding.
by Alan Pyke Posted on May 19, 2015
Many of the people best positioned to get rich by breaking the law say they have to cheat to succeed and that the regulators who hunt them are overmatched.
by Bryce Covert Posted on May 19, 2015
Female accounting clerks allegedly made $4 less an hour for the same work.
by Igor Volsky & Victoria Fleischer Posted on May 19, 2015
Do you know how much of the total gains since the recession went to the top 1% of Americans?
by Casey Quinlan Posted on May 18, 2015
Many Asian American advocacy groups are not supporting a discrimination complaint against Harvard University because they see it as a way to attack affirmative action policies.


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EDWARDSVILLE: Edwardsville Active Adult Center, 57 Russell St., is hosting a presentation on transitional care by a representative from Riverview Ridge at 11 a.m. on Aug. 27.
A discussion on heat stroke prevention and a blood pressure screening by Golden Living Center will take place at 11 a.m. on Aug. 28.
For more information, call 570-287-3381.
EXETER: The Cosmopolitan Seniors will meet at 1 p.m. today Aug. 20 in St. Anthony's Center. Host and hostesses are Aggie Abromavage, Rose Gunsior, Johanna Malinowski, Victor Malinowski and Marge Zinkavich.
The previous meeting was attended by 59 members and two guests. New pastor, the Rev. Finn was introduced to the club. Birthday celebrants were announced and Mary Dirhan was highlighted for her 98th birthday.
The 50-50 winners were Sam Ferrara, Ron McAdarra, Johanna Malinowski and Frances Poluske. Rosalie Ferrara won the special game prize and the guest of Cheryl Piphers won the bingo jackpot.
A casino trip is planned for September to Mount Airy with pick ups in Exeter and Pittston. Membership is not a requirement for trips. Call Johanna at 655-2720 for details.
PLAINS TWP.: Plains Senior Citizens Project Head held a meeting on Aug. 7 at SS. Peter and Paul school cafeteria, Plains Township. President Kevin O'Connor thanked members who helped at the Plains Crime Watch Night Out. The Chinese auction was a great success.
Michael Boncheck gave a report on the trip in September to Mount Airy Casino. The date will be announced at the next meeting. The cost is $20. Members and non-members are invited to contact Mike at 823-2871.
The next meeting will be held on Wednesday.There will be no hostesses at this meeting since there will be an ice cream social.
SWOYERSVILLE: The Swoyersville Senior Citizens will meet on Wednesday at St. Elizabeth Ann Seton Hall. New members are welcome. Winners of the 50-50 fundraiser were Helen Yurevich, Sue Barger and Liz Zdancewicz.
WYOMING: The Wyoming, West Wyoming Seniors will meet at 1:30 p.m. today at the St. Monica's meeting rooms with President Frank Prefinski presiding. Servers are Armonde Casagrande and Vicky Mecklavage.
Refreshments will be served after a brief business meeting and bingo will be played.
Fifty-fifty winners from the last meeting were Helen Markert , Marion Pocceschi, Olga Mizin and Angie Mastruzzo. Bingo jackpot winner was Marion Poccschi.
Birthdays for August are Olga Mizin, Joe Kosloski, Genny Rooney and Angie Zagursky.


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Mustang owners are a rather dedicated group and tend to relish learning as much as they can about their cars. Besides obtaining the original factory literature, reference photographs, technical data, and related information on their particular year and model Mustang, the owners love to read about "all things Mustang" as evidenced by the high number of Ford Mustang-specific books that have been published over the years.
Retail bookstores are an obvious source for automotive books, and besides the big book chains there's places like Wal-Mart, where you might find a book on Mustangs at a discounted price. Certain mail-order businesses that specialize in Ford parts offer a selection of Mustang books, and many of the major automotive swap meets across the country have vendors that sell automotive books of all kinds, including those that specialize in pony cars and Fords in general. Of course there's always garage sales and brick-and-mortar used bookstores for locating Mustang books, however sometimes it can be like finding the proverbial needle in a haystack.
The Internet has really had a major impact on book sales in recent years and is considered the best place to find a variety of automotive publications, and places like Amazon.com (http://www NULL.amazon NULL.com/) are great resources for finding these. In addition, Motorbooks.com (http://www NULL.motorbooks NULL.com/) sells its new publications direct, and there are also loads of books on eBay (http://www NULL.ebay NULL.com/) listed in both the auction area as well as eBay Stores, where they are purchased (often at reduced prices) via a "Buy It Now" feature.
One specific Web site that has helped me find a large number of the pictured Mustang and Ford books is Bookfinder4U.com (http://www NULL.bookfinder4u NULL.com/), a Web site that searches 130 bookstores and some 80,000 booksellers to find the best selection as well as the best prices on any particular publication you're looking for. The key to finding books is using the search engine of a site like this, and searches can be done by title, author, keyword (like Mustang), or ISBN number (International Standard Book Number), and this method provides perhaps the easiest way to really find out what is available online.
Books that are out of print are often more challenging to find, and the search engines are great for digging up the rarest of the rare. However, there's also the supply-demand situation with older books to consider; in many cases, they can be purchased at extremely low prices (1-cent!) with the only cost being shipping and handling (typically $3.99 or less.) Other books on topics like Boss 429 Mustangs that were originally printed in very low numbers are in extremely high demand and can cost several hundred dollars, if you can even find one for sale.
This article highlights a selection of Mustang/Ford books used for feature car magazine writing; this particular collection has been an ongoing effort, with the vast majority being purchased online. Because the goal was to obtain a high number of titles, price became a priority, and in some cases the book may have had a slightly damaged (or missing) jacket cover, but nearly all of them had clean, tight pages and are perfect for the research work for which they were originally obtained.
Anyone can go out and buy brand-new books at full retail prices; the trick was to shop around for the best deals! Rule of thumb on eBay is to avoid participating in "bidding wars," it's often better to wait for the item to come up again, without high competition from other bidders. If you really are serious about eBay, it's in your best interest to wait until the final moments of the auction to avoid showing other online bidders your "hand," and to bid once with your highest price to eliminate drama.
Also, the beauty of eBay is to use it as a tool to locate the names and descriptions of books you desire, but then to use that information to locate it elsewhere at a set price. Here's some general information on the books I've found and the prices paid for them:
Tags: books, ford, information, mustang, research