text:
HoopsHype Anthony Bennett rumors
The Minnesota Timberwolves duo are playing their first game in Canada as NBA teammates on Wednesday against the Toronto Raptors as part of Canada Basketball night. Before the game, they posed for a picture with Prime Minister Stephen Harper. Alas, in an embarrasing gaffe, the PMO's official Twitter tagged Bennett — whose Twitter handle is the really confusing @anthonybennett, not even an underscore — but identified him Kyle Lowry, the Raptors point guard, who is from Philadelphia. Yahoo! Sports
Ryan Wolstat: ie. Don't expect to see Tristan Thompson or Cory Joseph with Canada this summer, unless extensions done far sooner than anyone expects. They do expect Andrew Wiggins to play, Tyler Ennis, Stauskas, Anthony Bennett, Olynyk, Nicholson, etc. Twitter @WolstatSun
Wolves forward Robbie Hummel missed his 15th consecutive game Saturday because of a fractured hand. Saunders said he hoped Hummel would be playing by now and that doctors will take a further look at it this week. Saunders also said forward Anthony Bennett probably is two weeks away from returning from a sprained ankle. Minneapolis Star-Tribune
Anthony Bennett will be sidelined a minimum of two weeks with a sprained right ankle, the Minnesota Timberwolves announced Saturday. RealGM
Darren Wolfson: League people say they've brought Bennett up. Bud can be had. RT @aaronkarasov: @DarrenWolfson hearing any #Twolves trade chatter? Twitter @DarrenWolfson
"He hasn't played very well, and Robbie played very well," Saunders said, referring to Bennett. "When you're on the floor, you have opportunities. I just thought Robbie deserved the opportunity because he has been playing very well. A.B. has tried to fight through some things, been hurt a little bit. He'll get other opportunities. They will come. I don't feel he played with enough energy here lately, and I thought Robbie had." Minneapolis Star-Tribune
The Wolves have deemed Bjelica not ready for the NBA until now, partly because Kevin Love was their power forward previously and then because Saunders did not foresee ample playing time on a team that had just traded for power forward Thaddeus Young and Anthony Bennett. Young's future is uncertain: This summer he can opt out of his contract's final year, due to pay him $9.7 million next season. Bennett's future as the team's power forward of the future is no sure thing, either, judging by his uneven play this season. "The only reason we haven't brought him over earlier is because of some of the veterans we have," Saunders said. "It wouldn't have benefited him here." Minneapolis Star-Tribune
On the Wolves, family is paramount. After the fair, everyone went to dinner at the house of coach Flip Saunders. His son Ryan is an assistant coach. Two sons of retired coach Rick Adelman, for whom Saunders took over, are also on the team's staff. This is a milieu Wiggins and Bennett know well. Wiggins is one of six kids, Bennett the youngest of three. The party was a good one. Ribs were cooked. Wiggins' parents and Anthony's mother were there. It was a salve, the end of a summer in limbo. "It was just long," says Wiggins of the lead-up to the trade. "Not really knowing where you're going to end up." In November, Wiggins sits beside Bennett for an interview in a small, cinderblocked room at Target Center in Minneapolis. Despite the team's losing ways, both relish the chance to play and improve. "We couldn't ask for a better position," Wiggins says. "Like he said," Bennett adds, "we're in the best situation we can be." Toronto Globe & Mail
While Wiggins was born in basketball – his father Mitch played in an NBA final – Bennett came to the game as a teenager, after his mom moved the family to Brampton when he was 10. He is quiet, but teammates know another side. "He comes off like he's shy but he's not shy," says Brewer, who calls Bennett the "music man" for his extensive music catalogue. And on the court, Brewer declares, "once he gets more playing time he's going to show people why he was the No. 1 pick." Toronto Globe & Mail
A lot has changed for Bennett. He was traded to Minnesota, part of the package that netted Kevin Love for Cleveland. He dropped 20 pounds, thanks to a more active offseason and a three-week, end-of-summer boot camp with trainer Frank Matrisciano. He had surgery to remove his tonsils and adenoids, which has helped him sleep. He had laser eye surgery. Bennett has never worn contacts. Can't put them in his eyes. How bad was his vision before? "You see that white board?" Bennett said recently, pointing to a board no more than 10 feet away. "Last year, I couldn't read the writing on it." "Anything far, I couldn't really see," Bennett said. "I couldn't see the people in the stands. Now I can see the scoreboard. I can see what plays coach wants to run." Sports Illustrated
Saunders has gone out of his way to make Bennett aware that he believes in him. "I believe the biggest thing is we showed that we really care about him," Saunders said. "We work with him on a daily basis, whether it is in the film room or on the floor or just talking to him. There is a saying coaches use: A player is only as good as his coach thinks he is. If he feels the coach has confidence in him, he is probably going to play at a higher level. We have a lot of confidence in him." Sports Illustrated
"Anything far, I couldn't really see," Bennett said. "I couldn't see the people in the stands. Now I can see the scoreboard. I can see what plays coach wants to run." In Minnesota, Flip Saunders has tried to help Bennett by simplifying things for him. "He came in and the first thing I said to him was there are two things you are not going to do: You're not going to play small forward and you are not going to shoot three's," Saunders said. "Everyone has different ideas. That was just my evaluation. I believe right now he has a comfort level because he understands the position he is and what is expected of him." Sports Illustrated
Bennett's numbers early on have not been eye-popping. He is averaging 7.3 points in 15 minutes. He plays behind starter Thaddeus Young, getting the chunk of his minutes in the second and third quarters. But occasionally he shows signs of his enormous potential. Against Brooklyn, Bennett caught a pass in the paint and threw down a ferocious two-handed dunk over Nets center Mason Plumlee. At 21, Bennett has a lot to learn but for the first time he knows what is expected of him. "Last year I felt like I was always playing catch up," Bennett said. "This year, I know what coach wants from me. It feels a lot different." Sports Illustrated
Love was traded away in the offseason to Cleveland in a blockbuster move to acquire Andrew Wiggins, Anthony Bennett and Thaddeus Young. Wiggins was the centerpiece of the deal, and the Timberwolves are hoping he might be the face of the franchise in future years. It also appears he wants to stay here as he recently purchased a home in Minneapolis. "One thing a lot of people don't know is he moved his entire family up here, his younger sisters, his mom and dad. They bought a house here in the Twin Cities," Timberwolves vice president of communications Brad Ruiter told WCCO-TV's Ali Lucia on WCCO This Morning. "The fact that he moved his entire family up here tells me that he wants to put some roots down here." CBS Minnesota
Darren Wolfson: Rubio's contract not the only one on #Twolves minds before Oct. ends. They'll exercise 2015-2016 options w/ Muhammad, Dieng, and Bennett. Twitter @DarrenWolfson
Any rumor missing? E-mail us at firstname.lastname@example.com.


text:
Feb 9, 2010, 8:17 PM EDT
Among the things to now add to those NBA rookie introduction classes is "don't take nude pictures of yourself with your cell phone then ship them to women you are trying to impress." Yes, you would think that would be common sense, but…
The San Antonio Spurs guard George Hill is the latest to have his nude photos surface on the Internet when a spurned woman decided to get revenge.
"A year ago I made a mistake and take full responsibility for my actions. I have matured and learned from this episode," Hill said in a released statement where apologized to his girlfriend, family and Spurs fans.
Hill was a relatively unheralded guard out of Indiana University-Purdue University at Indianapolis, and is the only player from that school to ever make the NBA. And he is making the most of it, becoming a solid contributor to the Spurs playing 26 minutes a night and averaging 10.9 points per game. He is a good shooter, can hit the three (37% this season) and gets to the line. He's going to be in the league for a long time.
Hill's announcement comes on the heels of nude photos of Portland's Greg Oden being posted on the Web. Guys, put away the cell phone cameras, you're an NBA player — a celebrity — and if you send these photos out bad things are going to happen. And I really don't want to write any more of these stories.
- Craig W. - Feb 9, 2010 at 9:49 PM
You'all are certainly busy. I've lost count of the number of threads — just for today.
Maybe this subject shouldn't count as a complete post. I think nude photos may surface for the next 6 mos or so – from people having sent them out over the last couple of years – but I doubt there will not be any new occurrences going forward from this date.
Naive is too kind a word for these young men.
- Deon Wolma - Feb 11, 2010 at 11:26 AM
Online marketing is not just for the ongoing product, making a website or for letting customers buy items online. Online marketing can also include how a business proprietor can engage a work team. The measure of people who are taking computers, web design, and learning to host websites proves just how productive online marketing can make the employer, the employees, and the independent contractors. And with a sufficient Internet savvy team, your business earnings can increase too.
Top Posts
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- Dwight Howard hit with suspension-triggering technical foul 7
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subset: commoncrawl


text:
A method and system for controlling flow motion in a channel/cavity in a microfluidic system includes positioning at least one pair of electrodes in and/or proximate to the channel/cavity. A buffer solution is placed in the channel/cavity, the buffer solution having at least one dielectric property that varies in response to changes in temperature of the solution. An AC/DC voltage is applied to the electrodes to generate an electric field in the channel/cavity; the AC voltage having a known magnitude and frequency and the DC voltage having a known magnitude. The magnitude of the AC/DC voltage is adjusted to cause Joule heating of the buffer solution in the channel/cavity. The geometry and position of the electrodes is adjusted to generate a temperature gradient in the buffer solution, thereby causing a non-uniform distribution of the dielectric property within the solution in the channel/cavity. The dielectric non-uniformity produces a body force and flow in the solution. Also, the frequency of the AC voltage is adjusted to generate flow of the buffer solution in the channel/cavity in response to the non-uniform distribution of the dielectric property.
1. A method of mixing liquids in a microfluidic channel comprising:
a. placing at least two buffer solutions inside the channel, at least one buffer solution having a temperature-dependent dielectric property;
b. applying a potential difference to at least one pair of electrodes separated by a gap and positioned within one or more walls of the channel to induce a temperature gradient and non-uniformity of the dielectric property within at least one of the buffer solutions; and
c. controlling the applied potential difference whereby the non-uniformity of the dielectric property is produced within at least one of the solutions generates a flow motion within the solution wherein fluid is expelled away from or pulled toward the gap between electrodes.
2. The method of
3. The method of
4. The method of
5. The method of
6. The method of
7. The method of
8. A method of cleaning a microfluidic channel comprising:
a. placing a buffer solution inside the channel, the buffer solution having a temperature-dependent dielectric property;
b. applying a potential difference between at least one pair of electrodes separated by a gap and positioned proximate to one or more surfaces of the channel to induce a temperature gradient within the buffer solution;
c. controlling the applied potential difference whereby the temperature gradient induced in the solution produces a non-uniformity of the dielectric property within the solution; and
d. controlling the applied potential difference whereby the non-uniformity of the dielectric property produced within the solution causes fluid to be expelled away from or pulled toward the gap between the electrodes.
9. The method of
10. The method of
11. The method of
12. The method of
13. The method of
A portion of the disclosure of this patent document contains material that is subject to copyright protection. The copyright owner has no objection to the facsimile reproduction by anyone of the patent document or the patent disclosure, as it appears in the Patent and Trademark office patent file or records, but otherwise reserves all copyright rights whatsoever.
1. Field of the Invention
The present invention relates generally to devices and methods used for mixing and cleaning in microfluidic systems. More particularly, this invention pertains to employing electrothermally induced flow to enhance mixing of chemical and biological samples and cleaning in microscale devices.
2. Description of the Prior Art
Miniaturized bioanlytical or Bio-Micro Electro Mechanical Systems ("BioMEMS") (hereafter collectively referred as microdevices) are used to perform various functions such as a simple mixing of two or more analytes or liquid streams (hereafter collectively referred as samples) to a more complex biochemical assay that can include immunoassays, DNA hybridization, and general cell-molecule interactions. These devices incorporate many of the necessary components on a single platform, known as a biochip or microfluidic chip (hereafter collectively referred as microfluidic system). The term "microfluidic" is commonly used if at least one characteristic dimension of the device is in micron size. Typical biochip components known in the art include reaction chambers, pumps, micromixers, pre-concentrators, interconnects, separators, and sensors. The successful implementation of a biochemical assay using a microfluidic system is determined in terms of parameters that can include overall assay time, recovery time, sensitivity, selectivity, and accuracy.
In microdevices, samples are usually mixed as a part of an assay protocol. The time taken to accomplish this task, known as "mixing time", is determined by the diffusion coefficient (usually a very small value) of the samples, their flow speed, and residence time inside the device. This time can form a significant portion of the "overall assay time". In this regard, there is a need for methods and systems that will facilitate rapid mixing so that overall assay time may be reduced. Preferably, such devices should contain no moving parts.
A second performance parameter is the recovery time, which is defined as the time taken for the device to get ready before analyzing next set of samples. This requires cleaning of the device. In this aspect also, there is a similar need for systems and methods that will facilitate efficient cleaning.
Most conventional micromixing systems can be classified as either active or passive. Passive mixers use molecular diffusion of samples, and consequently take a very long time to accomplish mixing. Active mixers use externally imposed forcing mechanisms, such as a pressure pulse or an oscillatory flow, and therefore take a relatively short time to accomplish mixing. Known methods of micromixing include electroosmotic flow (electrohydrodynamic instabilities), static lamination (diffusional forces as mixing mechanism), and injection of one liquid into another liquid with microplumes.
Passive mixers do not have any moving parts, in contrast to active devices where moving parts are activated either by a pressure or by an electric field. Passive mixers use channel geometry to increase residence time. Passive micromixers are further subdivided into in-plane and out-of-plane mixers. In-plane mixers divide and mix various liquid streams in one dimension while out-of-plane mixers use three-dimensional channel geometries to enhance mixing. The simplest passive in-plane mixer is a one that merges two different liquid streams into a single channel and accomplishes mixing via molecular diffusion.
Cleaning methods that are conventionally practiced in the industry include ultrasonic cleaning and vacuum washing.
What is needed, then, are methods and systems for inducing flow in a microfluidic system that use no moving parts, are easy to control, and that do not require special treatment of surfaces in the system.
The present invention provides a novel method and system for inducing and controlling flow motion in a cavity or channel (hereafter referred to as a channel) in a microfluidic system. A cavity can be considered as a subset of a channel where one or both ends may be closed. A channel can have any cross sectional area, including square, rectangular, trapezoidal, circular or curved. The method of the invention includes positioning at least one pair of electrodes in and/or proximate to the channel. A liquid medium (hereafter referred to as a buffer) is contained inside the device. The buffer solution has at least one dielectric property that varies in response to the temperature of the solution. When an electric field, is applied to the buffer, it induces a temperature gradient in the buffer solution due to Joule heating. The applied electric field can be one of the following
The Joule heating, in turn, induces variations in the dielectric property of the buffer. The variation in the dielectric property exerts a force on the buffer and, consequently, a flow motion is observed. This motion is called an electrothermal flow. The present invention utilizes this electrothermally induced flow motion to accomplish the processes of mixing or cleaning. The magnitude, frequency and waveform of the electric field, the geometry and position of the electrodes, and geometry of the channel may be adjusted to generate a desired temperature gradient, hence desired flow, in the buffer solution.
The present invention includes a method of designing a microfluidic system to provide controllable flow motion in a buffer solution inside a channel having a fixed geometry. The designer begins by selecting either a buffer solution having a known viscosity, density and a temperature dependent dielectric property, or an electric power source having a voltage of known magnitude, frequency, and waveform. The designer then proposes a geometry of the device and a location and shape for at least one pair of electrodes to be placed in a position proximate the channel. The electrodes are connected to the electric power source. A target function that includes a desired temperature gradient inside the buffer solution and a uniformity of concentration of samples in the channel is defined. A computer simulation of the system is performed, using the selected system parameters. The simulation includes performing an optimization procedure on the target function. Following the initial simulation, the position of the electrodes can be adjusted in response to outcome. The design can further be optimized by adjusting one or more of the other system parameters, including the magnitude, frequency, and waveform of the electric voltage, and electrode shape and size, in response to performing the simulation of the system.
The use of electrothermal flows in a microfluidic system offers several advantages and benefits. First, no moving parts are involved in such systems. Also, such systems have low power requirements. For example, an electrode voltage in the range of 1 Vrms and frequency of 106 Hz (of an AC field) is able to induce a flow field with maximum velocity of 100 □m/sec in microdevices. Electrothermal flow provides an ease of control. Process parameters that induce electrothermal flows are easier to measure. This allows the control of device functionality to be accomplished with ease, for example, by rearranging the electrode configuration and changing the applied electric field.
A further benefit of using electrothermal flow is that there is no need for special treatment of the channel surfaces. The flow is induced within a region of non-uniform temperature gradient and is independent of more complicated surface phenomena. This means that no complex surface modifications are needed, as required in several commercial BioMEMS devices and therefore, is relatively easy to implement.
Traditionally, microdevices use electric fields (AC or DC) as a source of energy to induce flow of buffer using electroosmosis, transport and separation of samples using electrophoresis, or transport of particles using dielectrophoresis. In this context, the present invention focuses on the use of an electric field to facilitate the transport and mixing of two or more analytes or liquid streams, as well as cleaning (removal of particles or analytes) of devices using electrothermally induced fluid flow.
When an electric field is applied to a buffer, it induces a temperature gradient in the buffer solution due to Joule heating. This, in turn, induces variations (non-uniformities) in the dielectric property of the buffer. The non-uniformity in the dielectric property results in a body force being exerted on the liquid and, consequently, a flow motion is observed. The present invention utilizes this electrothermally induced flow motion to accomplish the processes of mixing or cleaning.
Dielectric materials experience an electrostatic force ({right arrow over (ƒ)}) in an electric field as described by:
This body force will contribute to the fluid motion governed by the Navier-Stokes equations:
Successful utilization of electrothermal effects to regulate flow within a microfluidic system relies on a correct choice of one or more of these parameters. For most applications, the thermal properties of the buffer solution are very close to those of water. The metal electrodes exhibit a much higher thermal conductivity as compared to glass, plastics or silicon, which are the materials most widely used in fabricating microdevices. Thus, thermal transfer within these materials can be discounted so that the materials are treated as being thermally insulated. Once the thermal parameters are chosen, the temperature change in the buffer solution will be determined primarily by the applied electric field. In Microsystems for biological applications, the temperature change should often be maintained within a certain range, typically less than two degrees. Because the typical geometry for which electrothermal flow is most effective involves dimensions measured from tens of microns to hundreds of microns (this also being the range for electrode dimensions), the applied electric potential should range from a few volts to tens of volts.
The dielectric properties of the buffer solution are fixed in most applications, although in some cases a specific material (such as an electrolyte) is added to modify the electrical conductivity. The variations in conductivity and permittivity as a function of temperature (α, β) can be found in the literature for most standard buffer solutions. For materials other than water, these two parameters may be different and must be determined by experimental measurement. The hydrodynamic properties of the buffer, such as the viscosity, are also fixed for a known buffer solution.
The applied electric field can be one of the following
From the expression of the electrothermal force applied to the buffer solution, the force changes sign, in the case of an AC applied electric field, as the frequency increases from zero to infinity. For most applications, the critical frequency, where the force changes direction, is in the order of megahertz and the transition band is quite sharp. Therefore, the frequency of the AC field can be in the kilohertz to gigahertz range, depending on what is needed to control the flow.
When applying electrothermal flow to facilitate mixing and cleaning, the physics of the flow for a basic electrode structure should be understood. Because of the complex interactions among the electric, thermal and flow fields, it is only possible to solve analytically the electrothermally induced flow in a simple electrode configuration. An exact solution of electrothermal flow in the vicinity of a pair of elongated electrodes (kept along the surfaces of a wedge), which are separated by a gap of the same width as the electrode, can be straightforwardly constructed. The flow field is fundamentally characterized by a pair of oppositely circulating zones above each of the electrodes. The direction of circulation direction depends on the direction of the electrothermal force. The easiest way to control the flow direction is to change the AC field frequency. Depending on the frequency, the flow can move toward or away from the center of the electrode. Because of the incompressibility of the flow, the fluid is expelled away or pulled toward the gap between the electrodes. The size of the circulation zone is approximately the same order of the size of the electrode. It is anticipated that the flow structure shares a similar topology for a pair of electrodes fabricated on each of the surfaces of a wedge region. For an array of periodical, co-planar electrode strips, the electrothermal flow is characterized by an array of circulating zones above each electrode. The direction of the flow is reversed for adjacent electrodes. The circulating zones are squeezed along the electrodes and therefore, they stretch in other directions. In general, the circulating zones are of comparable size to the electrode dimensions.
Although the local electrothermal force increases as the electrode gap decreases, the circulating zones are localized near the tips of the electrodes. This tends to work against a thorough mixing of fluid that is separated from the electrodes. In practice, however, the dimensions and the gap of the electrodes should be comparable with the other dimensions of the channel.
In general, issues that must be addressed for a successful design of a mixing or cleaning microfluidic system using electrothermal flow are summarized in the diagram shown in
All of these factors form a complicated optimization problem with certain restrictions. Accordingly, a preferred embodiment of the invention includes simulation of the proposed system using computational fluid dynamics (CFD) techniques and tools. For example, CFD-ACE+ multiphysics software developed and marketed by CFD Research Corporation, Huntsville, Ala., and its capability of optimization, can be used to determine the most suitable parameters. The CFD-ACE+ software modules of particular relevance to the present invention are fluid flow, heat transfer, multiple species transport, bio- and electro-chemistry, particle transport, and electrostatics.
Simulation-based process and device design is a rapidly emerging paradigm shift in the biotechnology and medical device industries. This design method relies on solving the laws of underlying complex, interacting, physico-chemical phenomena, and creating "virtual" device/process models. Compared to traditional empirical and laboratory analysis, this method provides a fundamental and detailed understanding of the device or process performance. A typical simulation-based design and optimization process for purposes of designing a microfluidic device using electrothermal flow consists of three basic steps:
(1) The designer creates a geometric representation of the system. The device is sub-divided into discrete non-overlapping three-dimensional cell volumes with the help of a computational mesh using a geometric grid generation tool.
(2) The governing system of nonlinear partial differential equations that describe fluid flow, heat transfer, multiple species transport, bio- and electro-chemistry, particle transport and electrostatics is solved. Simulations are performed for the prescribed values of process conditions such as magnitude, frequency and waveform of the applied electric field, buffer and analyte flow rates, and physical and chemical properties of the buffer and the analyte. In addition to these, the orientation and the number of electrodes can also be varied, and their implications on system performance can be analyzed.
(3) Finally, the performance of the device is analyzed using the post-processing tool.
If the performance of the system is found to be unsatisfactory, the designer will change either the process conditions and repeat steps 2 and 3; or will change the system geometry and repeat steps 1 through 3, until optimal (desired) performance is achieved. Steps 1 through 3 will be repeated if the number and orientation of the electrodes are changed.
Examples are provided below for design of mixing and cleaning systems using CFD design and simulation techniques in accordance with the invention. A 100 kHz AC electric field is used for each simulation.
A rectangular cavity 18 is shown in
The electrode pairs 12, 14 are electrically connected to an AC voltage source (not shown) that generates a voltage having a magnitude and frequency that are selectable/controllable by the designer/user in order to provide the desired flow motion control in accordance with the design criteria as described herein. In either embodiment, in order to provide the desired flow control the electrode pairs 12, 14 can be energized by the AC voltage source to work simultaneously, or they can be activated periodically.
In one embodiment, two buffer solution species SPA (1 nM) and SPB (3 nM) occupy the top and bottom half of a 200 micron�100 micron rectangular cavity. The solutions have diffusivities of 1 and 3E−10 m2/s, respectively. An AC voltage of 5 Vrms is applied to the electrodes. Model parameters are:
A concentration profile along the vertical axis at the center of the device is shown for both species SPA and SPB in
Note that the diffusion coefficients used for both species would classify them as small molecules. For macromolecules, such as proteins, the diffusion coefficient is expected to be at least an order of magnitude smaller, which would make the present invention even more effective (i.e. mixing time reduced by more than two orders of magnitude). Such results are presented in
As a further example, the electrode configuration in a rectangular cavity as shown in
In order to achieve optimal mixing while maintaining the temperature change within a certain range, the position of the electrodes on each surface of the cavity should be adjusted. To do this, the designer should define a target function that comprises temperature increase and the uniformity of the concentration. The position of the electrodes will be adjusted based on performing an optimization procedure of this target function. For example, the CFD-ACE+ software provides automatic implementation of the whole process.
Conventional methods of washing microcavities in a channel do not achieve good cleaning efficiency because of the closed circulation of the fluid in the channel. The conventional method to enhance cleaning is to use a time-dependent washing process which attempts to create chaotic flow. Electrothermal induced flow provides an effective way to achieve this objective. By placing one electrode in the channel and another outside but near the channel, a flow is induced which moves locally parallel to the side walls of the channel. This in turn carries along with it any analyte or sample trapped inside the channel, to a location above the opening of the channel, where washing flow will remove them. By repeating this process, i.e., turning the electrothermal flow on and off, the channel can be cleaned.
Removal of sub-micron/nano-particles trapped in a channel can be substantially enhanced by combining electrothermally induced flow with pressure-driven flows. To design and implement such a system, a simulation is performed for 20 nm particles initially uniformly distributed in a 20 micron�20 micron cavity along the lower channel wall. Such particle sizes and cavity dimensions are representative of those that exist in typical microfluidic systems. Two electrodes, 12 and 14 having a width of 10 microns are positioned 5 microns from the corner of the cavity and a 5 Vrms AC field is applied. The electrothermally induced flow creates a circulatory flow pattern within the cavity that levitates the particles. A parabolic flow in the channel is used to wash away the levitated particles. The results are shown in
At least one pair of electrodes 12, 14 (two discrete planar or curved) is needed to generate the electrothermally induced flow. These electrodes 12, 14 can be oriented in-plane or out of plane (0<=θ<=360 degrees) as shown in
Two basic electrode configurations can be used in simulations and in physical electrodes (along the surface of the microchannel); and (ii) a pair of electrodes placed on each surface of a wedge region. Analytic study of electrothermal flow in a wedge region due to a pair of in-plane electrodes on each surface, forming an angle of 0 (see
Methods for fabrication of microelectrodes on substrates are known. The most common method is photolithography which is well established in the semiconductor industry, as taught in X. Wang et. al. 2000 'Cell separation by dielectrophoretic field-flow-fractionation', Anal. Chem. 72, 832–839, which is incorporated herein by reference. Using this method, others have used microelectrode arrays to separate biological cells using dielectrophoresis. (M P. Hughes & H. Morgan 1999 'Dielectrophoretic characterization and separation of antibody-coated submicrometer latex sphere', Anal. Chem. 71, 3441–3445.) (incorporated by reference). A variation of this technique is direct-write electron beam lithography. Both methods are capable of fabricating multiple layers of metals on glass substrate. T. Muller et. al. 1999 'A 3-D microelectrode system for handling and caging single cells and particles', Biosensors & Bioelectronics 14, 247–256 (incorporated by reference) has developed a sophisticated procedure which combines laser ablation and photolithography to construct three dimensional microelectrodes on a glass substrate.
The simulation-based design and optimization process using CFD-ACE+software, for example, described in the previous section, will also be useful in the investigation and development of various devices/concepts using electrothermally induced flow phenomena. The methods and the systems that are described in the present invention related to sample mixing and cleaning in microsystems can be readily applied in other applications such as micropumps, microreactors, microjets, active valves and particle/cell sorting and counting. These devices find applications in the BioMEMS/biotechnology industry in the field of proteomics, genomics, diagnostics and high-density chemical analysis applications, and in polymerase chain reaction (PCR) chips.
Thus, although there have been described particular embodiments of the present invention of new and useful Methods and Systems Employing Electrothermally Induced Flow for Mixing and Cleaning in Microsystems, it is not intended that such references be construed as limitations upon the scope of this invention except as set forth in the following claims.
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Iron Crusade
100,000 - 500,000 downloadsAdd this app to your lists
+ By WYSE GAMES LTD
This is huge update, that change whole game! That's why all progress from last version will be lost.
Instead you will get compensation in lots of crystals.
Join the elite Imperial tank squad! Conquer planet after planet! Expand the Empire!
You think you are a veteran player and nothing can impress you? Then you have never played Iron Crusade. Experience the hardcore gameplay of Iron Crusade!
Iron Crusade is a single player, old school, turn-based action with classic 8-bit graphics and sound. Control the tank and survive in a deadly, fully destructible world. Everything can be destroyed –the enviornment, platforms, weapons, your enemies and even you…
You are the sole defense against hordes of enemy tanks! Turn on all your strategic skills to beat angry armored tanks. Use your imagination to slaughter challenging enemies. Attentively collect ammo, first aid kits, and crystals, used to upgrade powerful weapons and purchase mightier tanks. The only things of value in this cruel world are the crystals, your mind and brute force!
Beware of your enemies. Each enemy is smart and aggressive with a unique weapon and a special ability. Avoid the mine traps. You must survive! You must win! You are the last hope for the Empire!
And that's just the beginning. There's no time to spare, put on your helmet and fight for your Emperor!
Main Features:
-Mind-blowing, turn-based action!
-Old school graphics and sound!
-Fully destructible environment!
-30+ levels!
-14 different weapons to destroy your enemy!
-Unique player tanks with upgrades!
-Variable enemies and bosses on each planet!
Tags: iron crusade faq.
What's new in version 2.3.1
In short, now is much more easier to play.
But in details:
- again MORE crystals for gained stars!
- your tanks now have MORE health
- fixed bug with stars (just small bug)
- napalm and multishot price changed
What's new in version 2.3.0
- more crystals for gained stars!
- upgraded tanks are deal more damage
- crusader tank got regeneration
- fixed tutorial level
(43 stars)
(43 stars)
It is really hard to get through a level and use to be able to buy tanks now have to rummage through excrement to get them
(43 stars)
Great game! Very fun
(43 stars)
(43 stars)
(43 stars)
This is a cool game, but I think it's unfair to PAY for upgrades you've EARNED.. UNINSTALLED.
(43 stars)
This game was fun until it started pressing buttons I didn't, turns out it messes up the calibration on my touchscreen, and I have to restart my device to fix it.


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Originally written on Red's Army | Last updated 11/18/14
We're using this photo way too much this year… Nate Robinson bugged the **** out of me when he was with the Celtics with is ill-advised threes… but Doc Rivers always said he would occasionally win you a game. He did tonight for the Bulls, dropping 5 of 7 three pointers in a 100-89 Bulls win. To add to this craptastic effort, Joakim Noah dropped a triple double on the C's The Celtics had the lead down to 3… 70-67… with 3:40 to go in the 3rd. With 3:22 left in the 4th, it was 100-79. That's a 30-12 run over the span of 1 quarter. The Green: Rondo had a big scoring night, leading the way with a game-high 26. KG was hot early, and Pierce dropped 16 on 6-10 shooting. The Gross: Where to start…. The Celtics refused to defend… again. They gave up 28 and 27 point quarters to a not-so-great offensive team that was playing in a back-to-back while the Celtics had 2 days off. The Celtics without Garnett on the floor are putrid. They're almost as bad when Rondo's off the floor. Doc R
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Many of our clients proudly tell me they're good PowerPoint users because they've always adhered to the "One Slide Per Minute" Rule.
That's when I have to tell them it's a stupid rule that they need to abandon immediately (I make the point a bit more diplomatically when working with paying clients).
Sure, I understand why speakers are attracted to that rule: It offers them specific guidance that gives them an easy guideline for putting together their presentations. But the rule usually leads to disastrous results, for at least five reasons.
1. Gives Speakers Permission To Create Packed Presentations: The "One Slide Per Minute" rule says nothing about how much information should appear on each slide. As a result, many speakers pack 120 slides worth of information into 60 slides in an effort to fit everything in. Since they present only one slide per minute, they deceive themselves into believing they've created a good presentation – when in fact, they've only managed to produce a cluttered mess.
2. Nobody Wants To Look at 60 Slides An Hour: If I wanted to be put to sleep, I'd take an Ambien or watch a PBS documentary. When I see one slide per minute, I know I'm in for a snoozer.
3. You're Competing With Yourself: People can listen to you talk or read your slide. In the battle between the eye and the ear, social science finds that the eye wins, usually by an overwhelming margin. If the audience is reading what's on the screen, you may as well stop talking. Otherwise, you're just competing with yourself and wasting your time.
4. It Means Speakers Are Reading, Not Presenting: Speakers who put up slide after slide almost always read their slides to the audience. But since we humans can read five times quicker than you can speak, we're usually ahead of you. That means you'll annoy your audience when you continue reading the slides they already finished reading themselves.
5. The Slides Should Be For The Audience, Not You: Too often, slides are created more for the speaker than the audience – the speaker wants to remember what to say next, so he or she simply puts all of their thoughts on the screen. Visuals should be created to help the audience remember your points – not to serve as crib notes for the speaker.
So What Should You Do?
Here are a few questions to ask yourself before creating a PowerPoint slide:
Question 1: Does this slide represent visually what I'm saying verbally? Reinforcing your point with images helps the audience remember points better – but posting a list of uninteresting bulleted sentences quickly leads to audience fatigue.
Question 2: Is this slide intended to help me remember what to say next, or for the audience to better understand the concept I'm trying to explain? If it's the former, kill the slide.
Question 3: Most importantly, ask yourself whether you need to have a slide at all? Ask whether there's a more compelling way you can deliver your content without relying on an electronic gadget to do it for you.
Find these tips useful? Like us on Facebook to follow our tips designed to make you a more effective public speaker and media spokesperson. We're at www.Facebook.com/MrMediaTraining.
Related: The Five Most Common PowerPoint Mistakes
Related: Three Things To Do When The PowerPoint Crashes


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Spielberg On Spielberg
Steven Spielberg is undoubtedly one of the world's most successful, wealthy and admired filmmakers. His films have defined the past four decades – and have included record-breaking successes such as E.T., Jaws and Jurassic Park. Spielberg also manages to combine box office success with critical acclaim, with films like Close Encounters of the Third Kind,…More


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The U.S. Trademark Use Requirement and Associated Risks and Strategies for Chinese Applicants
Global Growth: A Prime Opportunity for the Middle Market
Dentons Dacheng Deal Done: Will BigLaw Follow Suit?
FCPA Compliance and Ethics Report-Episode 121-FCPA Year in Review, Part II
FCPA Compliance and Ethics Report-Episode 117-the Avon FCPA Enforcement Action
FCPA Compliance and Ethics Report-Episode 82, continued fallout from GSK in China
Examining Trends in Worldwide Design IP Filings
A Conversation with Lindsay Chu on Asia Restructurings
A Conversation with Rajiv Gupta on Asia Restructurings
The Changing Landscape of Intellectual Property in China
A Conversation with Ben Simpfendorfer on Asia Restructurings
A Conversation with David Heller on Asia Restructurings
A Conversation with Robyn Meredith on Asia Restructurings
Polsinelli Podcast - Conducting Business in China
FCPA Compliance and Ethics Report-Episode 15-GSK in China: a Game Changer in Compliance
China Outbound Investment
Russian Mergers & Acquisitions Market - Challenges and Opportunities
The FCPA Compliance and Ethics Report, Episode 3
China's Export Policy Changes After U.S. Antitrust Case
Jaffe Sees 'A Lot' of IPOs in 2013 'Pipeline'
When a national 'champion' is at stake, lively political and media debate often follows, sometimes even where the sector involved is not particularly 'sensitive'. This is unsurprising in markets facing slow economic growth...more
On January 19, 2015, China's foreign investment regulatory authority Ministry of Commerce ("MOFCOM") released a draft of new Foreign Investment Law ("Draft Law") (See blog article Comparison Chart re JV Law and Foreign...more
As highlighted in a report by the U.S. Senate Armed Services Committee, a flood of counterfeit electronic parts from China threatens the reliability of sophisticated defense technologies from thermal weapon sights to advanced...more
In This Issue:
- Commerce Department Action on Solar Trade Case
- Energy and Climate Debate
- Congress
- Administration
- Department of Agriculture
- Department of Commerce
The Committee on Foreign Investment in the United States ("CFIUS"), the inter-agency group that conducts national security reviews of foreign acquisitions of U.S. businesses, recently issued its Annual Report to Congress for...more
Number of Filings by Chinese Acquirers Increased Dramatically; First Transaction Blocked by Presidential Order Since 1990 -
The Committee on Foreign Investment in the United States (CFIUS), a multi-agency U.S....more
Chinese officials have long complained about American national security reviews, insisting they are an obstacle to Chinese investment in the United States....more
No longer cut from the cloth of 007's expensive suits, fast cars or well-mixed drinks, present-day espionage is carried out, to a great extent, through computer screens, proxy servers and spoofed e-mail addresses. Dubbed...more
March 8 (Bloomberg Law) -- With reports of corporate espionage and hacking on the rise, the US government and private companies need to take steps to prevent
the loss of trade secrets and threats to national security says...more
After A123 Systems filed for bankruptcy in October a number of companies looked to buy its assets. Now a sale to Wanxiang Group, a Chinese auto parts manufacturer, has been confirmed by the bankruptcy courts despite some...more
China's investments in the U.S. have increased rapidly and will continue to grow in order to acquire advanced technology, real estate, market channels and other assets. With solar module oversupply continuing through 2013 and...more
M&A activity in 2012 continued to be constrained by uncertain macroeconomic conditions, which have dampened dealmakers' confidence. Although there were several bright spots in transactional activity, momentum was difficult to...more
The Committee on Foreign Investment in the United States (CFIUS) recently released the unclassified version of its annual report to Congress for transactions notified to CFIUS during the calendar year 2011. Most notably, the...more
On October 8, 2012, the House Permanent Select Committee on Intelligence ("the Committee") published a report declaring two Chinese telecommunication equipment manufacturers, Huawei Technologies Company and ZTE, to be threats...more
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Compilation of why cruisers are UP
View Single Post
Join Date: Dec 2012
Posts: 460
# 306
Originally Posted by
Damage is linear while defences use a [1-1/(1+x)] type of model to prevent reducing damage to zero. If resistances stacked in a linear fashion then you could conceivably reach 100% resistance and avoid all damage, regardless of how much an attacker buffed it. That's what you need to keep in mind, they are independent of each other. Attackers deal damage while defenders resist percentages. That's why it doesn't matter how high an attacker buffs their damage, a defender will always take a % of it. The higher the resistances the lower the % taken.
This type of damage mitigation is often favored in game design because it allows a lot of latitude without being limited by hard caps. Granted it gets hit with ridiculous DR at high defensive values and then it becomes a design balancing act as gear inflation takes place. I would even propose the reason we haven't seen ships really go up in power dramatically is an attempt to keep gear progression in check since they already know that defences are already hitting really high percentages if players really decide to go for it.
Edit: I agree that a mere +2 to turning would make cruisers a lot more fun to play and would even add their effectiveness since they could more reliably get to critical spots.
Also, I think its true that in the game's original design all ships did comparable damage and had comparable survivability... they would just go about it in different ways. I don't know WHY that plan was abandoned as it really would make the game more interesting.
All that said I think cruisers suffer the most from having poor pilots. Lets not kid ourselves, for a new player leveling in an escort or sci vessel is HARD. They don't know how to stay alive and deal damage so they gravitate towards cruisers that can easily carry anyone through the PvE levelling content without actually teaching anything about how to play. I know this because that's what I did. It wasn't until I saw someone being effective with a non cruiser that I started to look at HOW to build ships and use them properly. I would say a lot of the people complaining cruisers are drastically underpowered have noticed others playing well and instead of choosing to learn themselves prefer to complain. Perhaps they are a cruiser fan that desperately wants their favorite ships to be above all others in everything, perhaps they simply don't think they should be forced to learn a totally different game than the one they played while pve leveling in a cruiser (a valid complain actually), or maybe they are still in the process of learning and will understand how to get the most out of their ships eventually.
On the other hand if someone's complaint is that the way the ship roles have evolved into high dps/medium survivability, medium dps/high survivability, and High CC/medium survivability is not to their liking and has several flaws as a system... that can be valid. Honestly, at this point I'm not sure how to bring all ships to do equal DPS, while having equal survivability... except maybe making cruisers more like escorts? Lower their defences while adding a few points of turning and maybe switching an eng console to a tac one? Admittedly what I suggest is more or less making fed cruisers into KDF battlecruisers. Do KDF players feel their cruisers are underpowered too?
Okay took me awhile, but I think I get it.
So if my FDC had resistance 50% from consoles and the like and gets hit for 1000 damage it will block 500 hp of damage, but if I get hit for 2000 damage I block 1000 damage and if I got hit for 26,000 damage I'd only take 13,000 damage, blocking the other 13,000.
So an Escort attacking me with say a 100 percent damage bonus is actually dealing less then 50 percent of that bonus to me in damage. So if the escort deals 500 damage originally and with a hundred percent dealt an additional 500 damage I would block 250 from his original base damage and 250 from his bonus damage for 500 in total effectively negating his entire bonus even though his attack bonus is a 100 percent and my resist is only 50% because his bonus is based only on his base damage, while my resist is based his total damage dealt.
I think the simplest way of explaining the advantage of armour stacking is that points of damage blocked scales automatically with increases in damage dealt, but the reverse is not true.
Judeo jutisu, you use thier strength against them.
As for cruisers aside from the Borque or what ever its called, FDC are probably the closest the KDF has to Fed Cruisers and I fly one and honestly I've found I'm alot more survivable in it then my fed escort. How much my hanger has to do with that I don't know, although I have 250 more crew and .1 shield thingy and an extra ensign sci Boff over the Advanced Heavy Cruiser the closest the Feds have to comparing to my Dacoit. I'm a tact commander btw, grade 26. Same turn speed and hull though as the Advanced Heavy Cruiser.


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We got Nala on Tuesday. She settled in as typical bossy kitten. She seems to have a bit of a split personality.she will be purring away demanding attention and then turn . Vet has said this is typical savannah behaviour and she will need time out. We have also been told to walk her on a lead. Just ordered her a harness as she hate the collar lead.
Bought her kitten biscuits but as you can see she prefers the Maine coon bolders. 2 fill her up


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PR for Startups over breakfast
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ASUS Chairman Jonney Shih promised the next iteration fo the Eee Pad Transformer would be impressive, and according to new reports his words could be an understatement. Multiple sources are claiming the next Transformer, scheduled for a launch sometime in the fall, will be the first device to feature NVIDIA's quad-core Kal-El SoC. The timing is slightly off from the original timeline set forth by NVIDIA. August was initially pegged as the month for Kal-El's debut, but it would now seem that things have shifted back slightly. Either way, we eagerly await the potential of four cores pumping out Android goodness.
[via Engadget]
Continue reading:
- ASUS Germany Confirms Android 4.1 Jelly Bean
- ASUS Eee Pad Transformer receives 220.127.116.11 OT
- ASUS pushing yet another minor update to orig
- CyanogenMod 9 nightlies now available for mor
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Polsinelli Podcast - Pharmacy Compounding: What's Next in Regulation?
Uncovering Factory Farming - The Effects of Ag Gag Laws
Polsinelli Podcast - Food Safety Modernization Act
Stealth Lawyer: Tama Matsuoka Wong, Forager for Restaurant Daniel
Regulatory Challanges When Bringing a Vehicle to Market in the United States
The Farm Credit Administration has adopted a new final rule governing the ownership and use of unincorporated business entities (UBEs) by Farm Credit System institutions. It applies to investments by System institutions in...more
A summmary and business implications analysis of climate policy and carbon pricing after the 2010 Australian Federal election....more
All, I am in the business of facilitating Gas & Oil negotiations, lease and addendum drafting and litigation. As my G&O practice grows each day, along with the industry itself, I find myself always increasing the protective...more
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text: Right downtown and by the beach. There are other places to stay of course but this one is ideal in our estimation. The rooms with a kitchenette are great for staying three days or longer. Be sure to go for a walk on the boardwalk in the morning before it gets hot and in the evening for fabulous sunsets. Our... More


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Illinois credit union now reporting high adoption rate for mobile app it introduced earlier this year.
Piedmont Advantage Credit Union in Winston-Salem, N.C., plans to acquire East Coast Credit Union in Wilmington, N.C., on Nov. 30.
A Pittsburgh attorney, on behalf of three blind clients, has sued seven credit unions and several more banks, claiming their ATMs don't comply with the Americans with Disabilities Act's standards for accessible design.
Mid-Hudson Valley Federal Credit Union, Kingston, N.Y., announced the promotion of Wayne Winkler to president/CEO. Winkler was named Acting CEO in April of 2012.
Suit targets credit unions in Pennsylvania, Texas and California and says at least half of ATMs in U.S. are non-compliant.
Wayne Winkler had served as acting CEO since April.
Hirings, promotions, career moves.
In 2010, the Filene Research Institute conducted a study, "Customer Experience and Credit Union Opportunities." One of the key takeaways from the report centered on a perplexing fact.
The Great Recession forced some women to take an even more active role in managing the household's finances.


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Celebrity Central / Top 25 Celebs
Eva Mendes
Eva Mendes Celebrates Her Birthday with Ryan Gosling on Wheels
The couple were spotted at a roller skating arena with their daughter Monday
Ryan Gosling Spent the Oscars … at Disneyland!
The actor was spotted over the weekend at the happiest place on earth
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Plus: How Ryan Gosling and Eva Mendes spent their night away from baby Esmeralda
Ryan Gosling and Eva Mendes Have a 'Relaxed' Date Night
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Six weeks after giving birth, the actress gets back to work shooting a commercial in L.A.
Ryan Gosling and Eva Mendes's New Baby, and the Week's Other Top Stories
See the five stories that got the strongest reactions from readers over the past seven days
Ryan Gosling Is 'Madly in Love' with His and Eva Mendes's Baby Girl, Source Says
He and Eva Mendes are getting help from some special family members, a source tells PEOPLE
Throwback Thursday: See Which Stars Supported Zach Braff's Garden State Premiere 10 Years Ago
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The hunky actor was "very supportive about keeping things a secret," says a source
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Ryan Gosling and Eva Mendes 'Could Not Be More Excited' for Baby, Says Source
Mendes, who is expecting the couple's first baby this October, is "feeling great"


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During the pre-trip inspection, you must show that the vehicle is safe to drive. You will have to walk around the vehicle and point to or touch each item and explain to the examiner what you are checking and why. You will have to point to or touch items under the hood or under the vehicle (this will require you to physically maneuver/crawl under the hood or under the vehicle).
Regulations in red are new this year.
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Retail Managment Network
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Select Local Merchants
Planet Beach Contempo Spa Fort WorthRead MoreA wildly successful alternative to traditional day spas?its more than 300 locations blanket 36 states and half a dozen countries?Planet Beach Contempo Spa is a futuristic relaxation station where state-of-the-art machines administer all the spa and tanning services. These friendly automatons sometimes replace familiar treatments, as in the Luminous facial, a light-based service that delivers blemish-busting results similar to those of a conventional facial. But other equipment maps out new spa territory entirely: the hydro-derma fusion chamber moisturizes the whole body with nutrient-rich steam in order to offset the effects of a dry climate or a rear-end collision with a salt truck. Other machines whiten teeth, spray tan skin, and massage muscles. Planet Beach operates on a gym-style membership system, meaning that members purchase packages or pay flat monthly rates. As members spend more time at the spa, they get to know the helpful assistants who are always on hand to demonstrate how to use the equipment without activating its ability to cry.2881 Matlock RoadMansfield, TX US
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By David Fong
Regional Sports Content Manager
TROY — One year after inducting the inaugural class into the Trojan Athletics Hall of Fame, the second class has been announced.
The Trojan Athletics Hall of Fame Committee and Troy High School Athletic Department has announced the 2014 class will include: Carlton Kazmaier (football, basketball, golf and track coach), Leslie Wells (football and baseball player), Mike Lyons (gymnastics and track), Heath Murray (baseball) and Levi Fox (cross country, track).
The inaugural class contained 10 members, while this year's class will include five members.
"We felt that five was a good number for this year and moving forward," committee chairman John Terwilliger said. "We've still got a lot of great candidates out there that we will eventually get to."
This year's class will be formally inducted Aug. 29 at Troy Memorial Stadium prior to the Troy football team's season opener against Chaminade Julienne. The following day, a banquet will be held in their honor at the Crystal Room in Troy.
A look at this year's class:
Carlton Kazmaier
Kazmaier arrived in Troy in 1940 as an assistant football coach. He took over as head coach in 1941, a position he held through 1951. During his time as head football coach at Troy, Kazmaier's teams compiled a 73-27-6 (69 percent) record. During one four-year stretch, the Trojans went 36-3-1, winning a pair of conference titles and finishing as runner-up twice.
In his final seven years as Troy's coach, the Trojans went 55-10-1 (83 percent) and earned the first 10-win season in school history (1946). That season, the Trojans outscored opponents 202-24 with six shutouts.
Kazmaier also served as Troy's varsity basketball coach on two separate occasions. From 1945-48, the Trojans went 49-11 under Kazmaier, capturing league titles in 1945 and 1946. He returned as head coach from 1954-56, capturing a league title in 1956.
From 1952 until his retirement in 1969, Kazmaier served as the school's golf coach. Under his reign, the Trojans won Miami Valley League titles consecutively from 1962-65. In 1963, the Trojans finished second as a team at the state championships. In 1964, Troy went 17-0 in match play, the first time that happened in school history. Troy sent six teams to state during his coaching tenure.
From 1941-43, Kazmaier served as an assistant track and field coach, taking over as head coach from 1944-46.
Leslie Wells
From 1904-1907, Wells played second base or shortstop on the Troy baseball team and offensive and defensive halfback and kicker on the Troy football team. In 1906, he was a player and the coach for a Troy team that went 8-0.
Following his career at Troy, Wells went on to The Ohio State University, where he was a two-sport athlete as well. In 1908, he was the starting halfback and kicker for the Buckeye football team. He scored three touchdowns in a game against Ohio Wesleyan. In 1909, Wells was the leading rusher and scorer for the Buckeyes. In 1910, Wells was named team captain. He was selected to the All-Ohio College Football Team and was named one of the top five players of the decade at OSU for 1900-1910.
In 1911, Wells served as an assistant football coach at Ohio State. He also lettered two years in baseball for the Buckeyes, 1909 and 1910.
Mike Lyons
Lyons was a state champion gymnast for Troy in 1977, capturing a state title in the still rings with a score of 9.85. That year, he also placed second in the all-around, second in the floor exercise, third in the parallel bars and third in the high bar. As a team, Troy placed fourth at state that year.
During his career at Troy, Lyons also was a team captain and a Western Ohio League champion in the all-around, rings, floor, parallel bars and high bar.
Following his career at Troy, Lyons went on to Iowa State University, where he competed from 1977-1981.
In 1980, Lyons captured second in the rings at the NCAA national championship meet, earning him All-American honors. In 1981, he served as team captain and captured the ISU Alumni Award.
Lyons' athletic career didn't end after college. In 2010, Lyons — owner and operator of CrossFit Troy — took sixth place in the Masters Division at the CrossFit World Championships. The following year, he placed eighth.
Heath Murray
Murray is one of two Troy High School graduates to have pitched in Major League Baseball.
In 1990, as a junior at Troy, Murray went 9-4 with a 2.39 earned run average and 102 strikeouts in 78 innings. He helped lead the Trojans to Division I district and regional titles. He was selected All-Greater Miami Valley Conference and all-district.
In 1991, as a senior, Murray went 12-1 with a 0.16 ERA and 165 strikeouts in 92 innings pitched. He led the Trojans to a GMVC title, a Division I district title and a regional runner-up finish. He was named first-team All-GMVC, the Division I district player of the year, first-team All-Ohio and was the "Mizuno Co-Player of the Year."
Following his career at Troy, Murray went on to pitch at the University of Michigan. He lettered four seasons, earning All-Big Ten honors as a junior and senior. He was a third-round draft pick of the San Diego Padres. In his debut with the Padreds, he out-dueled pitching legend Greg Maddux to pick up his first-career MLB win.
During his Major League Baseball career, Murray played for the Padres, Tigers and Indians. Between his time in the minors and big leagues, Murray compiled a total of 61 wins, 857 strikeouts and a combined ERA of 3.98.
Following his retirement from baseball, Murray has served as an assistant basketball and baseball coach at Troy. He currently serves as Troy's pitching coach.
Levi Fox
Fox graduated from Troy in 2005 as the most-decorated cross country and track athlete in school history.
In track and field, Fox captured a state championship in the 3,200-meter run as a senior. He also was a Greater Western Ohio Conference champion in the 1,600 and 3,200, a district champion in both distance events and a regional champion in the 3,200. As a junior, Fox took second at state in the 3,200. He also was a district champ in the 1,600 and 3,200 and regional runner-up in the 3,200. As a sophomore, Fox placed fourth at regionals and 12th at state in the 3,200.
Fox still holds school track and field records in the 1,600 (4:16), steeplechase (6:31), 3,200 (9:10), 5,000 (15:23) and as a part of the 4x800 relay (7:57).
In cross country, Fox was a state runner-up as a senior. That year, he also took first at districts and second at regionals. He placed in the top 10 in the Footlocker National Championship meet, good enough for All-American honors. As a junior, Fox placed fourth at state, first at districts and fifth at regionals. As a sophomore, he took second at districts and finished in the top 25 at state.
Following his career at Troy, Fox competed in both cross country and track at The Ohio State University, lettering three times in both sports. He was a part of two Ohio State cross country teams to qualify for nationals and two Big Ten runner-up cross country teams.
Contact David Fong at firstname.lastname@example.com; follow him on Twitter @thefong


text: [ Bobby Deen Talks New Book 'From Mama's Table To Mine' on Joy FM [AUDIO] By Laura Daniels February 21, 2013 Yes, I'm still giddy like a school girl. Read More Category: Lifestyle, Mix Morning Rush Tags: Bobby Deen, Cooking Channel, Food Network, nl, paula deen Send to a friend! Share on Facebook Share on Twitter Pin it! Reddit This! Share on Tumblr!


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KrabiOperating day:
DailyOperating time: 08.00 - 18.00
Contact Details
- -
79 Mu 5 Tambon Ao Nang, Amphoe Mueang, Krabi 81000
Tel. +66 7562 2163, +66 7561 2811-2, +66 7562 2164
Category : 岛屿
Attraction Details :
One of the best known archipelagos in Thailand is located approximately 40 km from Phuket. Phi Phi Archipelago contains two islands: Phi Phi Don and Phi Phi Le, sitting 2.2 km away from each other and both islands are home to natural wonders, irresistible beaches and breathtaking views. Visitors can appreciate the nature either a day tour to both islands or an overnight stay on Phi Phi Don. Selections of tour service to other Andaman islands such as Surin, Similan, Lanta, and Tarutao Islands can be booked ahead of time in Phuket or Krabi.


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Cabinet officials to talk to Congress about Syria
WASHINGTON President Barack Obama said Tuesday he's confident Congress will authorize a military strike in Syria, as lawmakers were holding their first public hearing about how to respond to respond to last month's alleged sarin gas attack outside Damascus.
Obama met with congressional leaders at the White House as part of his push to win over support for his request for authorization for limited military strikes against Syrian President Bashar Assad's regime. He indicated he is open to changing the language to address lawmakers' concerns, but urged them to hold a prompt vote.
"So long as we are accomplishing what needs to be accomplished, which is to send a clear message to Assad, to degrade his capabilities to use chemical weapons, not just now but also in the future, as long as the authorization allows us to do that, I'm confident that we're going to be able to come up with something that hits that mark," Obama said.
With war-weary Americans skeptical of sparking another long-winded intervention, Obama tried to assure the public involvement in Syria will be a "limited, proportional step."
"This is not Iraq, and this is not Afghanistan," Obama said.
After a decade of war in Iraq and Afghanistan, polls show most Americans opposed to any new military action overseas. That reluctance is being reflected by senators and representatives, some of whom say Obama still hasn't presented bulletproof evidence that Assad's forces were responsible for the Aug. 21 attack. Others say the president hasn't explained why intervening is in America's interest.
The meeting in the Cabinet room included House speaker John Boehner, House Democratic Leader Nancy Pelosi and Senate Minority Leader Mitch McConnell, along with other members of leadership and the heads of the committees on armed services, foreign relations and intelligence. Secretary of State John Kerry, Defense Secretary Chuck Hagel and Joint Chiefs Chairman Gen. Martin Dempsey also attended before heading over to Capitol Hill for testimony later in the day before the Senate Foreign Relations Committee. A classified briefing open to all members of Congress was to take place as well.
Obama won conditional support Monday from two of his fiercest foreign policy critics, Republican Sens. John McCain of Arizona and Lindsey Graham of South Carolina.
A congressional vote against Obama's request "would be catastrophic in its consequences" for U.S. credibility abroad, McCain told reporters outside the White House following an hour-long private meeting with the president.
But despite Obama's effort to assuage the two senators' concerns, neither appeared completely convinced afterward. They said they'd be more inclined to back Obama if the U.S. sought to destroy the Assad government's launching capabilities and committed to providing more support to rebels seeking to oust Assad from power.
"There will never be a political settlement in Syria as long as Assad is winning," Graham said.
McCain said Tuesday he is prepared to vote for the authorization that Obama seeks, but the Arizona Republican also said he wouldn't back a resolution that fails to change the battlefield equation, where Assad still has the upper hand.


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RoboReel pulls in its power cord at the touch of a button
The RoboReel is a motorized extension cord winder, that incorporates several safety and convenience features
Using an optional mount, the RoboReel can be located on a wall
The 15-amp RoboReel comes with a user-replaceable 50-foot (15.24-meter) 12-gauge electrical cord
Article Summary
The winding up of extension cords is something that most of us probably don't give a lot of thought to – we loop them on the ground, spool them around our forearm, or perhaps use a spring-activated or hand-cranked winder. If you're someone who spends a lot of time putting cords away, however, you might want to make the job safer and easier. That's where Great Stuff's RoboReel comes in. It's a portable motorized cord winder, with some interesting features.
« Back to RoboReel pulls in its power cord at the touch of a button
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Property Details
6 Bedrooms, 5 Full Bathrooms, Sleeps 14
Welcome to Alfred House, a new, luxurious, and secluded beachfront estate on the north end of world-famous French Leave Beach (formerly Club Med Beach). There are no houses between this house and the mile-long beach of pink sand where a Club Med once stood, the most sought-after beach location on Eleuthera. The ocean is turquoise, shallow, and historically safe, having served Club Med well for many years. Enjoy thousands of feet of deserted beachfront, extensive ocean views from every major room, and the sound and smell of the ocean from everywhere.
Alfred House is a newly constructed, 4000-square-foot, 5-bedroom Bahamian Colonial home plus one-bedroom guest cottage (800 square foot), located just 50 feet from the beach. The house was designed and decorated to reflect the laid back feeling of the cabanas at the Bitter End Yacht Club, Virgin Gorda. Both the upstairs and downstairs of Alfred House have a wall of glass french windows, so as you move through the house, you see the sea at every turn. The house is furnished with distressed Indian teak antiques and custom pieces made of teak, mango, & cherry woods, and black and white photographs of movie icons.
Downstairs, Alfred House features a vast great room that looks out through a wall of glass french doors at the beach and ocean. The open-plan kitchen faces the ocean, and features custom wooden white shelving with Mexican shell encrusted stone countertops. Appliances are stainless steel. The kitchen island is capped with a ten-foot teak counter with matching teak bar stools.
There are Honduran hardwood floors, cypress cedar ceilings, marble and slate tile, and mini-split air conditioning units. The upstairs features a huge media room overlooking the sea, along with four bedrooms, with a fifth bedroom downstairs. Four of the bedrooms have huge ocean views. The fifth has a hill/sunset view. Three large bedrooms have king beds; the two smaller bedrooms have two twin beds in each. The three king suites have ensuite bathrooms. There is a powder/shower room downstairs. The media room upstairs is huge, another gathering spot, and faces the ocean and shows turquoise water through several french doors.
The upstairs sun deck, with its grand row of honduran mahogany shutters, runs the length of the house (60 ft), with miles of beach and ocean views. It is furnished with comfortable white lounge chairs. Beneath it is a covered terrace, a shady spot for enjoying the sea breeze and the sound of the ocean. The floor of the terrace contains a lovely mosaic of a conch made by a local island artist. Seating for drinks or coffee is available on the ground terrace, where you can see and hear the ocean.
Alfred's guest cottage, called Med Point, is perched right on the edge of the ocean with a huge 1100-square-foot teak wrap-around deck. It is 800 square feet, and has it's own kitchen, in a large great room. The cottage is available for an additional charge (see Rates for details). If you don't require use of the guest cottage, it will be left empty. We will not rent it to anyone else.
Amenities at Alfred House include full AC, a large flat-screen TV with DVD in the media room, high-speed internet with WIFI. The house does not have cable or satellite TV.
Alfred House is surrounded by over 20 acres of secluded wild nature, full of casuarina trees, coconut palms, giant cacti, sea grape and lettuce, even though we are only a mile or so from town. (See the aerial view). Explore French Leave Beach, and see the ruins of the old Club Med, which was swept away by a hurricane. The grounds and gardens of Alfred House have palms, palmettos, cacti, hibiscus, and oleander. We have a beautiful copper coloured coral garden off the Med Point deck, on which geckos sun themselves, and which has a natural blowhole that spouts water 30 feet on windy days. There is excellent snorkeling right off our property.
WALK 20 MINUTES INTO TOWN, through Club Med Beach, and buy lobster or grouper, freshly caught every day around 2 pm. The local fishermen will clean the fish for you, and provide only lobster tails, if you wish. A CHEF CAN BE ARRANGED FOR NIGHTLY SERVICE. Daily maid service is available for additional charge.
There is a fantastic sandy jogging/walking path, shady in places, in both directions along the beach. The wooden upstairs deck and terrace below are suitably wide for yoga. There is a wide outdoor stairway, so that children can run out into the garden. The outdoor shower faces the ocean and the palm filled garden. The back garden has a vegetable patch, which is available for guest use.
A 15 minute walk down the beach from Alfred House will take you to the beautiful Beach House Restaurant, where you can enjoy tapas and drinks on the large beachfront deck. The famous bar/restaurant Tippy's is just two miles away, and you can drive through Club Med beachfront to reach it. A 20 minute walk (or 5 minute drive) in the other direction takes you to Sky Beach Bistro, another great beachfront restaurant and pool bar.
Recent Review
The best in beach properties!
The caretakers do a wonderful job of maintaining the property and they are available to take care of any need you have at a moment's notice. We had a problem with an air conditioner and it was repaired within 2 hours.
We love the atmosphere of the location. You feel like you are on a deserted island, but all the amenities and restaurants in Governor's Harbor are just minutes away. We especially enjoyed dining at the 1648 restaurant in the new French Leave Resort.
We would recommend Alfred House to anyone who wants a first-class beach experience in Eleuthera.
About the Manager
Guestbook comments from the manager
Your home is beautiful and we loved everything about Eleuthera and our stay at Alfred House. It was the perfect spot to relax and a wonderful place to come home to after our many adventures in and around the island. Your welcome letter and tips were so helpful. My children said Eleuthera is one of their very favorite places we've ever visited (and we travel quite a bit). We all hope we can return one day soon! Many thanks again!
10 Reviews
4.8 based on 10 traveler reviews
The best in beach properties!
The caretakers do a wonderful job of maintaining the property and they are available to take care of any need you have at a moment's notice. We had a problem with an air conditioner and it was repaired within 2 hours.
We love the atmosphere of the location. You feel like you are on a deserted island, but all the amenities and restaurants in Governor's Harbor are just minutes away. We especially enjoyed dining at the 1648 restaurant in the new French Leave Resort.
We would recommend Alfred House to anyone who wants a first-class beach experience in Eleuthera.
Amazing location!!
On the negative side the house does not have its own water supply and water has to be brought in by a truck and put in the tank so there is very little water pressure and if you want to take a shower it comes in little dribbles so don't expect a good hot shower. Additionally, there is no hard lined phone service here nor Internet so both phone and Internet have to be through cell service which can be difficult. The house is in a remote location which we love because we enjoy the privacy and yet it is only around a five minute drive to a town where you can buy most of your groceries so we found the location to be delightful. Additionally being on the Atlantic Coast of Eleuthera it is often very windy so make sure to bring a windbreaker as even during the days the winds blow quite briskly.
amazing vacation home--ritz- carlton quality
Eleuthera Paradise
Eleuthra's Best!Eleuthra's Best!
The caretaker of Alfred House met us at the Governor's Harbour airport and helped us get settled in. She checked in on us during the week and was only a phone call away.
If you want luxury accommodations, the most beautiful beaches on the island, privacy yet being close to stores and restaurants, you can't find a better place than Alfred House. We will certainly be back.
This is one of the nicest properties on Eleuthera!
From the Owner
"Club Med Solo, Secluded Atlantic Beach Front, suitable as a Work Retreat or Family Reunion Place."
Activity and Interests
Alfred House is set on a point between 2 beautiful beaches: Club Med Beach, which is shallow and safe and superb for snorkelling, and boogie boarding, and Casuarina Beach, which is 1000 feet from Twin Cove Beach, which has the finest snorkelling in town. The town of Governors Harbour, less than a mile away, is an easy and pleasant walk along the beach, and up a small hill. Snorkel and swim off our wide pink sand beach, then shower in our garden.Alfred House is on a point between Club Med Beach (French Leave) and Casuarina Beach, so you have your choice of 2 beaches to step onto. 1000 feet up the beach is Twin Cove Beach which has the finest snorkeling in Governors Harbour. Our beaches are shallow, and historically safe, protected by a large reef system. The water is among the clearest in the world. Walk half a mile to THE BEACH HOUSE RESTAURANT, for tapas and live music on the beach. Sky Beach Bar is about 2 miles away along the beach. On Casuarina Beach, turtles nest at night, because it is so gloriously unspoiled. There is a SUPERB SANDY JOGGING PATH extending north and south, along our beach, which is by times shrouded in foliage, and by times open to vistas of the ocean, on the old Banks Road, which is far more secluded and rustic than Banks Road on the south. One of the loveliest drives on the whole island, is the drive north, from Alfred House, to Knowles Drive, along the water, on the Old Banks Road. There is a youtube video on this. You will brush palm trees and sea grape, and see rare birds and hear the crickets sing. This is Club Med Solo. Set up your iPod and do yoga on the deck as the sun rises over the Atlantic
Rental rates
|Rate Period
|Weekend Night
Base Rate 2015
Jan 4 2015 - Dec 18 2015
7 night minimum stay
Dec 19 2015 - Jan 3 2016
7 night minimum stay
Base Rate 2016
Jan 4 2016 - Dec 18 2016
7 night minimum stay
Payment is usually accepted in the quoted currency (USD) unless the currency and the amount is specifically agreed in advance with the owner / advertiser.
Additional information about rental rates
RATES ARE FOR UP TO 10 GUESTS. For more than 10 guests, the guest cottage can be added for $1500/week. For more than 12 guests, additional charges apply.
Cancellation Policy
- 12
- Available
- 12
- Unavailable
- 12
- Today
From the Owner
"So close to the ocean, that there is instant accessibility for quick swims several times a day."
Property Type
- estate
- Away From It All
- Air Conditioning
- Alarm Clock
- Basic Soaps
- Broadband Access
- Ceiling Fans
- Clothes Dryer
- Hair Dryer
- Internet
- Laundry Soap
- Linens Provided
- Paper Towels
- Parking Off Street
- Safe
- Toilet Paper
- Towels Provided
- Washing Machine
- Wireless Internet
- 4 Ring Stove
- Blender
- Coffee Maker
- Cooking Utensils
- Dishwasher
- Freezer
- Kitchen
- Microwave
- Oven
- Refrigerator
- Toaster
- Dining Area
- Books
- DVD Player
- Music Library
- Television
- Video Library
- Groups
- Singles
- children welcome ...
- limited accessibility
- non smoking only
- pets not allowed
- suitable for elderly or infirm
Location Type
- Beach View
- Beachfront
- Ocean View
- Oceanfront
- Rural
- Village
- Waterfront
- arboretum
- bay/sound
- botanical garden
- caves
- churches
- cinemas
- duty free shops
- library
- marina
- pond
- reefs
- restaurants
Leisure Activities
- beachcombing
- bird watching
- boating
- eco tourism
- photography
- scenic drives
- shelling
- sight seeing
- walking
Local Services & Businesses
- ATM/bank
- Babysitter
- groceries
- laundromat
- massage therapist
- medical services
Sports & Adventure Activities
- cycling
- deepsea fishing
- fishing
- fly fishing
- hiking
- jet skiing
- kayaking
- mountain biking
- pier fishing
- sailing
- scuba diving or snorkeling
- snorkeling
- snorkeling/diving
- sound/bay fishing
- spelunking
- surf fishing
- surfing
- swimming
- tennis
- water skiing
- wind-surfing
Floor Area
- 5000 sq. ft.
- 5 Bathrooms
- Bathroom 1 - toilet, shower
- Bathroom 2 - toilet, shower
- Bathroom 3 - toilet, shower
- Bathroom 4 - toilet, shower
- Bathroom 5 - toilet, shower
- 6 Bedrooms, Sleeps 14
- Bedroom 1 - 1 king
- Bedroom 2 - 1 king
- Bedroom 3 - 1 king
- Bedroom 4 - 2 twin/ single
- Bedroom 5 - 2 twin/ single
- Bedroom 6 - 1 king
- Balcony
- Beach Chairs
- Beach Towels
- Beach Umbrellas
- Deck / Patio
- Deck Furniture
- Lawn / Garden
- Outdoor Furniture
- Outdoor Grill
- Outdoor Grill Gas
- Patio
- Wood Deck
- Yard
- Guests provide their own meals


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- Exchange: New York
- Sector: Consumer Discretionary
- Industry: Retail - Discretionary
- Sub-Industry: Department Stores
JC Penney Co Inc+ Add to Watchlist
As of 20:04:04 ET on 05/22/2015.
Company Profile for JC Penney Co Inc (JCP)
J.C. Penney Company, Inc., through a subsidiary, operates department stores in the United States and Puerto Rico. The Company provides merchandise and services to consumers through department stores, catalog departments, and the Internet. JCPenney markets primarily family apparel, jewelry, shoes, accessories, and home furnishings.
Contact Information
JC Penney Co Inc
Key Executives for JC Penney Co Inc (JCP)
|Myron E Ullman III "Mike"Chief Executive Officer
|Marvin R EllisonPresident/CEO-Designee
|Edward J Record "Ed"Exec VP/CFO
|D Scott LavertyExec VP/CIO
|Brynn EvansonExec VP:Human Resources
|Dennis P MillerSenior VP/Controller
|Kristin HaysSenior VP:Communications
|Kirk WaidelichSenior VP:Sales Promotion & Mktg
Quotes delayed, except where indicated otherwise. All prices in local currency. Time is ET.
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Ignazio Silone
Ignazio Silone (ēnyä´tsyō sēlō´nā), 1900–1978, Italian novelist and journalist, whose original name was Secondo Tranquilli. A Socialist and for a time a Communist, he broke with Stalin and supported Trotsky in the late 1920s and thereafter, devoting his writings to attacking Fascism and promoting Socialism without sacrificing human and literary values to his thesis. He fled Italy in 1931, and, after living in Switzerland, he returned to his native country in 1944 to become editor of the newspaper Avanti. His novel Fontamara (1933, tr., 1934) was rewritten after World War II to reflect his matured political thought; an English translation of the second version appeared in 1960. Silone's other works include Pane e vino (1937, tr. Bread and Wine, 1962); La scuola dei dittatori (1938; tr. The School for Dictators, 1938); The Living Thoughts of Mazzini (tr. 1939); Il seme sotto la neve (1940; tr. The Seed beneath the Snow, 1942); Uscita di sicurezza (1951; tr. Emergency Exit, 1968); and L'avventura d'un povero cristiano (1968; tr. The Story of a Humble Christian, 1970). Silone contributed critical and political articles to various periodicals.
See biography by S. G. Pugliese 2009).
Ignazio Silone: Selected full-text books and articles
Ignazio Silone; Eric Mosbacher.
Harper & Brothers, 1961
Michael Hanne.
Berghahn Books, 1994 (Revised edition)
Nathan A. Scott Jr.
King's Crown Press, 1952
Peter Bondanella; Julia Conaway Bondanella; Jody Robin Shiffman.
Greenwood Press, 1996 (Revised edition)
Whit Burnett.
Dial Press, 1950
Irving Howe.
Horizon Press, 1957
McDonald, Michael P.
The National Interest, Fall 2001
Pryce-Jones, David.
New Criterion, Vol. 20, No. 1, September 2001