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A handheld ultrasound instrument is disclosed having enhanced diagnostic modes including pulse wave Doppler, time-motion analysis, and tissue harmonic imaging. An external electrocardiograph (ECG) recording unit is also disclosed. The ECG unit is adaptable to be used with the handheld ultrasound instrument to provide for ECG monitoring while performing an ultrasound scan in B-mode, Doppler, color Doppler, M-mode, and PW mode. The enhanced handheld ultrasound instrument further includes a security mechanism allowing any combination of the diagnostic modes to be enabled by the manufacturer, and later to enable or disable any one or group of the diagnostic modes. The invention also discloses a method for a manufacturer to maintain a database of handheld ultrasound instrument capabilities after the instruments enter the stream of commerce.
1. A handheld ultrasound device weighing less than fifteen pounds, including a transducer, beamformer and image processor and a first digital signal processor capable of processing B mode and flow (2D Doppler) scans, having an second digital processor block comprised of a FPGA circuit and a second digital signal processor core comprising:
a digital Doppler QBP filter for filtering PW Doppler signals; and
a PW Doppler signal processing circuit.
2. The handheld ultrasound instrument of
3. The handheld ultrasound device as described in
4. The handheld ultrasound device of
5. The handheld ultrasound device of
6. The handheld ultrasound device of
7. The handheld ultrasound device of
8. An ultrasound diagnostic instrument comprising:
a) a handheld module including a display, manual controls, and system circuitry for processing signals for display;
b) a transducer assembly coupled to the system circuitry for providing electrical signals from ultrasound waves for processing; and
c) an electrocardiograph (ECG) module coupled to the handheld module by a cable and including leads for receiving ECG signals from a patient and ECG signal processing circuitry for applying ECG signals to the handheld module through the cable.
9. The ultrasound diagnostic instrument as defined by
10. The ultrasound diagnostic instrument as defined by
11. The ultrasound diagnostic instrument as defined by
12. The ultrasound diagnostic instrument of
13. The ultrasound diagnostic instrument as defined by
14. The ultrasound diagnostic instrument as defined by
15. The ultrasound instrument as defined by
16. The ultrasound instrument as defined by
17. The ultrasound diagnostic instrument as defined by
18. The ultrasound diagnostic instrument as defined by
19. For use with a handheld ultrasound diagnostic instrument, an electrocardiograph (ECG) module comprising:
leads for receiving ECG signals from a patient;
ECG signal processing circuitry; and
A cable for applying ECG signals from the ECG signal processing circuitry to the handheld module.
20. The ECG module as described in
21. The ECG module as defined by
22. The ultrasound instrument as defined by
23. The ultrasound instrument as defined by
24. The ECG module as defined by
25. The ECG module as defined by
26. The ultrasound instrument as defined by
27. The ultrasound instrument as defined by
28. In an electrocardiograph (ECG) module having first signal processing circuitry for processing ECG signals from a patient and second signal processing circuitry for further processing of the ECG signals for diagnostic use, a power supply circuit for providing electrical power from the system to the first signal processing circuitry comprising:
a) a serial inductive path for receiving a DC voltage and a shunt capacitive path and a shunt switch connecting the serial inductive path to a power ground;
b) a first coupling capacitor for coupling the serial inductive path to the first signal processing circuitry and a second coupling capacitor for coupling the power ground to the first signal processing circuitry; and
c) a rectifying circuit in the first signal processing circuitry including a forward polarity diode connecting the first coupling capacitor to a first terminal of a positive charge capacitor and a reverse polarity diode coupling the first coupling capacitor to a first terminal of a negative charge capacitor, and an isolated reference terminal connected to the second coupling capacitor and to a second terminal of the positive charge capacitor and to a second terminal of the negative charge capacitor whereby electrical power is coupled through the coupling capacitors to the charge capacitors at the frequency of the shunt switch.
29. The power supply circuit as defined by
30. A light weight, handheld system for performing electrocardiography comprising:
a handheld ultrasound device weighing less than seven pounds having a transducer, a beamformer, an image processor and one or more digital signal processors for signal filtering, detection and mapping; and
a portable electrocardiogram monitor weighing less than three pounds and having at least three electrical leads for measuring electrical potential across a person's chest, a differential amplifier for amplifying the measured electrical potential, a plurality of signal filters and gain amplifiers, and a means for electronically isolating the measured signal from other electrical inputs and interferences.
31. The system of
32. In a programmable diagnostic ultrasound instrument having stored software and data for operation control, a software security mechanism which restricts modification of software or data including an algorithm which generates a keycode based on a unique system identifier which allows a person or agency to perform a system or data update.
33. The programmable diagnostic ultrasound instrument of
34. The programmable diagnostic ultrasound instrument of
35. The ultrasound instrument of
36. The ultrasound instrument of
37. The ultrasound instrument of
38. An ultrasound instrument having a software library and data for operational control stored on a persistent memory device, and having a means for securely enabling and disabling applications within the software library.
39. A programmable diagnostic ultrasound instrument having a plurality of diagnostic modes, wherein access to the diagnostic modes is controlled through a gate flag registry, the gate flag registry capable of modification through a verification procedure utilizing a secure means for extracting hidden bits from a keycode based on one or more unique system identifiers.
40. The programmable diagnostic ultrasound instrument of
41. The compound algorithm of
42. The compound algorithm of
43. The programmable diagnostic ultrasound instrument of
44. The programmable diagnostic ultrasound instrument of
45. The programmable diagnostic ultrasound instrument of
46. The compound algorithm of
47. The programmable diagnostic ultrasound instrument of
48. The ultrasound instrument of
49. The ultrasound instrument of
50. The ultrasound instrument of
51. In a programmable diagnostic ultrasound instrument having stored software and data for operation control, a software security mechanism which restricts modification of software or data utilizing a 64-bit mixing algorithm and a bit-wise signature generator within an architecture using a X-OR logic to perform reversible encryption and decryption operations, thereby allowing a user to change software or data using a short sequence of numbers while providing the security of a large bit string verification scheme enabling signature verification, error correction and licensing verification.
52. The programmable diagnostic ultrasound instrument of
53. The programmable diagnostic ultrasound instrument of
54. A system for the tracking diagnostic modes in one or more programmable diagnostic ultrasound instrument(s) comprising:
a) a general purpose computer having a means for generating a unique keycode for each programmable diagnostic ultrasound instrument, the keycode having encrypted error detection bits, signature bits and options bits for enabling diagnostic modes in a particular instrument;
b) at least one programmable diagnostic ultrasound instrument having a plurality of diagnostic modes that can be enabled or disabled upon successful verification of the keycode, the verification procedure utilizing a secure means for extracting hidden bits used to modify a gate flag registry from the keycode; and
c) a data structure for centrally recording and tracking diagnostic modes of each diagnostic ultrasound instrument.
55. A system as described in
56. The system as described in
57. The system of
58. A method of upgrading the functional software of a programmable diagnostic ultrasound instrument comprising the steps of:
(a) generating a keycode generation algorithm comprising at least one encryption algorithm, at least one signature generator, and a reversible logic operation for mixing a bit string produced by said encryption algorithm and a bit string produce by said signature generator;
(b) generating a keycode using the keycode generation algorithm, said keycode utilizing data specific to a programmable diagnostic ultrasound instrument and data relating to a desired software upgrade;
(c) inputting the keycode obtained from the step (b) into the programmable diagnostic ultrasound instrument; and
(d) verifying the keycode generated by step (b) in the programmable diagnostic ultrasound instrument, using a reversing algorithm of step (a) to compare and verify the signature bits, error detection bits and option bits.
59. The method of
(b1) inputting instrument specific information into a keycode encryption algorithm;
(b2) providing one or more secret constants to the keycode encryption algorithm;
(b3) executing the operation of the encryption algorithm;
(b4) choosing a series of options to enable, each option coding for a desired software upgrade, in the programmable diagnostic ultrasound instrument and entering the series of options into a signature generator algorithm;
(b5) generating a first bit string in the signature generator having an equal length to a second bit string produced by the encryption algorithm;
(b6) executing a X-OR function on the first and second bit strings to produce a third bit string;
(b7) converting the third bit string to a decimal string; and
(b8) producing a keycode.
60. The method of
(c1) loading a new software application into the programmable diagnostic ultrasound instrument; and
(c2) enabling the new software application by inputting the keycode obtained from the vendor, into the programmable diagnostic ultrasound instrument.
61. The method of
(d1) converting the license string into the X-or bit string;
(d2) generating a second bit string by running the encryption algorithm internally within the programmable diagnostic ultrasound instrument;
(d3) reversing the X-or logic on the X-or bit string and the second bit string to produce a first bit string;
(d4) isolating the signature bits, option bits and error detection bits of the first bit string;
(d5) comparing the signature bits, the option bits and the error detection bits generated by the reverse X-or first bit string to the internally generated first bit string; and
(d6) enabling the necessary options programmed through the option bits.
62. The method of
63. The method of
64. The method of
65. The method of
66. The method of
1. Field of the Invention
This invention relates primarily to a handheld ultrasound instrument having various diagnostic modes and detachable modules. Also included is a means for manufacturer to strictly control the operational capabilities of the handheld ultrasound instrument after the instrument has entered the stream of commerce.
2. Description of the Prior Art
As is well known, modem ultrasound diagnostic systems are complex systems, many of which employ computer control circuits. The computer circuits, in turn are controlled by software and data, which is typically stored in some form of addressable memory associated with the instrument. This memory may be, for example, semiconductor memory or a rotating magnetic disk. As ultrasound systems have become more sophisticated, they have employed a greater quantity of software and data in the control of the instrument.
An advantage of extensive use of software programmable instruments that may rely on other stored data for operation is that new capabilities can be added or enabled by modifying this software or data. Also, design or implementation defects in software or data can be corrected by modifying the software or data. Modification of the software or data may be accomplished by introducing new software or data via a portable representation, such as a removable magnetic disk, optical memory, or semiconductor memory, or via an electronic communications network. The same mechanisms may be applied to alter existing software or data as opposed to introducing new software or data.
A significant limitation of current mechanisms for update or modification of data or software associated with diagnostic ultrasound systems is that of control of the update or modification process. Regulatory requirements typically stipulate that manufacturers must keep accurate records of any modification to diagnostic systems, including software or data updates. Thus the modification process must be restricted in some way so that appropriate data can be maintained. In addition it is desirable to limit access to certain functions of an instrument in order to provide lower cost, limited functionality systems that may later be upgraded with more extensive functionality. Typical mechanisms employed currently to implement such control over the modification process are either cumbersome or ineffective. Service personnel may be sent to a customer site to perform the process, or instruments may be returned to a central facility for update. Either mechanism incurs significant expense in both money and time. Other mechanisms may be employed to allow users of the instrument to perform the update process, but this limits the control that the manufacturer has over the process.
In accordance with the present invention, a handheld ultrasound instrument is provided having a group of diagnostic modes not previously available in portable devices due to restrictions on both weight, and signal processing capabilities in small circuit devices. ECG capacity is also described using a separate module to preserve weight in the handheld instrument, as well as a secure control means for the upgrade and control of the diagnostic capabilities of ultrasound instruments while providing a means to maintain a detailed user database are disclosed.
The first embodiment of the present invention is a handheld ultrasound device weighing less than fifteen pounds including a transducer, beamformer and image processor, a first digital signal processor (DSP), a second digital signal processor (DSP) block comprised of a DSP core and an external field programmable gate array (FPGA). The first DSP is capable of processing B mode and flow (2D Doppler) scans. The second DSP comprises a digital Doppler QBP filter for filtering PW Doppler signals and a PW Doppler signal processing circuit.
The ultrasound instrument may also have the capacity for time-motion display, frequently referred to as M mode. M mode signal processing occurs on the first digital signal processor using a micro-code block, and the interpolation of M-mode signal for video display is done on the second digital signal processor.
In an embodiment of an ECG module, ECG functionality is added to a handheld diagnostic ultrasound instrument without significantly increasing the weight or cost of the instrument. More particularly, an ECG module is provided with a cable system connector for connecting the module to the handheld ultrasound instrument. The module includes leads for interfacing with a patient and the basic electronics for ECG signal processing including amplification and filtering of signals for use by the handheld unit. In a first embodiment the module includes electrical ground isolation for isolating the patient leads from the system signals and ground. The module houses the ECG electronics with a first stage amplifier and filter provided in the isolated portion of the module and all other ECG electronics provided in the handheld ultrasound instrument of the module.
Alternatively the first and second stage amplifiers and filters are in the ECG module, as well as a display signal processor, for formatting the signal into a displayable format. The display signal is then exported to the display of the handheld ultrasound instrument. The display export may be in analog format, or through a analog to digital converter, and exported as a digital signal. Amplified and filtered signals from the patient leads are optically coupled from the lead portion to the system portion of the ECG module. Necessary power for the lead portion is generated using either capacitive or inductive type power converters from the system power supply to the isolated portion of the ECG module. Thus the patient is not ground connected directly to the system ground reference.
More particularly, the power supply circuit includes a serial inductor for receiving a DC voltage and a shunt capacitor and a shunt switch connecting the serial inductor to a power ground. A first coupling capacitor capacitively couples the serial inductor to an isolated first power processing circuit, and a second coupling capacitor couples the power ground to the first power processing circuit. A rectifying circuit in the first power processing circuit includes a forward polarity diode connecting the first coupling capacitor to a first terminal of a positive voltage capacitor, and a reverse polarity diode connecting the first coupling capacitor to the first terminal of a negative voltage capacitor. An isolated reference terminal is connected to the second coupling capacitor and to a second set of terminals of the positive voltage capacitor and the negative capacitor whereby electric power is coupled through the coupling capacitors at the frequency of the shunt switch to the isolated signal processing circuitry.
In accordance with the principles yet another embodiment of the present invention, a diagnostic ultrasound instrument is provided with a software security mechanism that effectively restricts modification or replacement of software or data associated with the instrument. Updates to software or data for a particular type of instrument can be developed and easily distributed, but control over the actual update or modification of any specific instrument is retained.
In one embodiment, a "keycode" is generated via an algorithm that takes a unique system identifier and information regarding the modification or update to be performed as inputs. Software in the instrument to be updated prevents any update or modification of the instrument's software or data unless the correct keycode is provided by the person or agency performing the upgrade process. Requiring the person or agency performing the update to obtain the keycode from one or more authorized agencies allows the manufacturer to control such upgrade process to satisfy both regulatory and feature-control requirements. This mechanism does not require service personnel to perform the update process, nor is any movement of the instrument to an update facility required. Update software, data, and keycodes may be provided via a variety of mechanisms including portable memories, communication networks, facsimile, or voice and manual input via the instrument's user interface.
In a second embodiment, the ultrasound device has a software library located in a persistent memory. The software library is used for data and operational control. A security means is provided for enabling and disabling individual components of the software library.
In a third embodiment, a programmable ultrasound instrument is provided having a plurality of diagnostic modes. Access to the diagnostic modes is controlled through a gate flag registry. The gate flag registry can be modified through a verifying a keycode. The verification procedure utilizes a secure means for extracting hidden bits from the keycode. The keycode is based on one or more unique system identifiers.
The keycode is generated by a manufacturer or authorized agent utilizing a keycode generating program. The keycode encodes for the diagnostic modes to be enabled. Once the keycode is entered into the programmable diagnostic ultrasound instrument, the instrument executes the verification procedure on the keycode. The process allows the ultrasound instrument to decrypt the keycode and recover a large array of bits from the small keycode. These bits include the desired option bits (for enabling the desired diagnostic modes), error detection bits, and signature bits. The latter two used to verify the authenticity of the keycode.
Another embodiment of the present invention includes a programmable diagnostic ultrasound instrument having stored software and data for operational control. Part of the stored software is a software security mechanism that restricts modification of the software or data utilizing a 64-bit mixing algorithm and a bit-wise signature generator. The mixing algorithm and the signature generator each produce a bit string that is processed through a reversible logic operation. The resulted bit string is used to code for an alphanumeric keycode. The keycode can be "decrypted" by reducing the alphanumeric information into a bit string, then executing the reversible logic on the bit string to produce the two bit strings originally produced from the mixing algorithm and the signature generator. The two bit strings are verified against the originally produced bit strings via an encryption process inside the ultrasound instrument. If the bit strings are verified, then diagnostic modes are enabled (or disabled).
A system for tracking the diagnostic modes in programmable diagnostic ultrasound instruments is also disclosed. The system comprises a general purpose computer, ultrasound instruments and a data base. The computer has a program or logic board for generating a unique keycode for each programmable diagnostic ultrasound instrument. The keycode having encrypted error detection bits, signature bits and options bits for enabling diagnostic modes in a particular instrument. Each programmable diagnostic ultrasound instrument has a plurality of diagnostic modes that can be enabled or disabled upon successful verification of the keycode. The verification procedure utilizes a secure means for extracting hidden bits used to modify a gate flag registry from the keycode. Finally a data structure for centrally recording and tracking diagnostic modes of each diagnostic ultrasound instrument is used to keep track of every instrument, and their operational diagnostic modes. This system is useful in complying with government regulations covering medical devices, and ensuring a manufacture can maintain control over the operational features of the devices it makes or sells, as required by law.
In addition, a method of upgrading the functionality of a programmable ultrasound instrument is disclosed. The method comprises several steps. First entering instrument specific data and desired option data into a keycode generating algorithm. Second, generating a keycode using the keycode generation algorithm. Third, inputting the keycode obtained from the keycode generator into the programmable diagnostic ultrasound instrument, and fourth, verifying the keycode by running the keycode generation algorithm locally on the ultrasound instrument, but utilizing a "decryption" mode to compare and verify the signature bits, error detection bits and option bits.
These and other embodiment of the present invention will become readily apparent upon a detailed inspection of the detailed description of the invention, and a study of the appended claims.
FIG. 1 is an exterior view of a hand held ultrasound instrument.
FIG. 1A is a side view of the apparatus of FIG. 1B.
FIG. 1B illustrates an ECG module for use with a handheld ultrasound instrument.
FIG. 1C is an end view of the apparatus of FIG. 1B.
FIG. 2 illustrates a high level architecture block diagram of the present invention.
FIG. 3 is a block diagram of the primary DSP ASIC used.
FIG. 4 is a block diagram of the secondary DSP used.
FIG. 5 illustrates a block diagram for an external ECG module.
FIG. 6 illustrates a power scheme for an external ECG module.
FIG. 7 shows a flow chart overview of the license manager.
FIG. 8 shows a detailed flow chart of the license generator.
FIG. 9 shows a detailed flow chart of the license decryption algorithm.
FIG. 10 shows a system incorporating the elements of the present invention for tracking individual unit capabilities.
In reading the description of the present invention and its many embodiments, the following terms are used outside of their ordinary "dictionary" definition:
By "Keycode" we mean an alphanumeric or simply numeric character string used to represent an end user license for enabling a feature in the present invention. The "keycode" is the string of characters that a vendor or manufacturer of the present invention provides to a user for them to enter at a certain prompt of an ultrasound instrument. The keycode itself is an encoded character string, and when properly decrypted, yields large volume of instrument specific information for use specifically with an ultrasound instrument.
By "Ultrasound instrument" we mean any device specifically designed to use a transducer to produce and receive ultrasound waves for use as a diagnostic tool in evaluating a patient's medical condition or state. Ultrasound instrument refers in general to hand held portable ultrasound instruments weighing less than fifteen pounds. However one embodiment of the present invention applying to keycodes for use with ultrasound systems is specifically excluded from the under fifteen pound weight restriction and is meant for use with any ultrasound instrument.
An ultrasound instrument that is highly mobile is ideally suited for use with the present invention. The security and tracking system permits a mobile ultrasound unit to be tracked by its manufacturing serial number, and to have its full capabilities recorded in a central database regardless of where the instrument is located. Thus anyone who wishes to determine if an instrument has certain diagnostic features enabled on a particular mobile ultrasound instrument need only identify the unit by its serial number and call the manufacturer for the operational mode information. Mobile ultrasound instruments maybe more susceptible to tampering as they are may be taken to places outside of the proper control of a hospital or physician, and be tampered. Therefore it is helpful to illustrate a hand held portable ultrasound instrument in the context of the present invention.
A highly mobile or portable ultrasound instrument having the security mechanism of the present invention incorporated into its architecture or software library is shown in FIG. 1. In general form, the ultrasound instrument 100 includes a handle 102 for easy carrying. The instrument has a separate transducer (not shown) for sending and receiving ultrasound waves. The received ultrasound waves are interpreted by the diagnostic programming executed on the hardware of the instrument 100. The resulting images are displayed on a display device 104. The display device may be any type compatible with the instrument, such as a LCD, or a passive/active TFT screen. Screens commonly use with laptop computers may be used for portable ultrasound instruments, while CRT screens, TV monitors or large high definition monitors maybe used with larger, non-portable systems. The ultrasound instrument usually has a control or user interface 110 with which a user can instruct the instrument 100 to perform a variety of diagnostic modes, or data analysis commands. The instrument has a QWERTY style keyboard 112 as well as a cursor controller 114 or "mouse" type feature. In a more specific design, an ultrasound instrument 100 incorporating the present invention also includes an array of visual controls 130 (such as near 132, far 134, gain 136, brightness 138 and contrast 140), and a group of menu keys 120 for allowing a user to make an easy selection of the more common programmed features of the instrument 100. A battery indicator 150 is included to permit a user to identify when the instrument 100 needs to be recharged, or when the battery should be replaced. An audible warning may also indicate when the battery is low. The instrument of the present invention has a speaker (not shown) built into the handle 102, and the handle acts as a sound chamber enhancing the sound quality. The display 104 is hinged so that it may be elevated from the main unit 100 during use for ease of viewing ultrasounds during operation.
FIG. 1B shows an external ECG module 500 such as one usable with the handheld ultrasound instrument 100. The ECG module 500 possesses an interface 170, cable 172, signal processing housing 174 and connector ports 176 for connecting ECG leads RA, LA and LL.
Numerous input/output ports are provided on the side of the instrument. An audio out, ECG receptacle that also provides serial data out (through a special adaptor), docking station data transfer, and video out. While the instrument of FIG. 1 illustrates an ultrasound device having the present invention integrated within, the present invention is not limited to the device as shown in FIG. 1.
FIG. 2 illustrates the architecture of a hand-held ultrasound system of the present invention. A transducer array 210 is used for its solid state, electronic control capabilities, variable aperture, image performance and reliability. Either a flat or curved linear array, or a phased array may be used. The elements of the array are connected to a transmit/receive ASIC 220 which drives the transducer elements and receives echoes received by the elements. The transmit/receive ASIC 220 also controls the transmit and receive apertures of the array 210 as well as the overall signal gain and frequency response. The filter that sets the frequency response of the receive path may be a low pass filter to minimize alias artifacts due to the sampling of the data in the front end ASIC 230. Optionally, to support tissue harmonic imaging (THI mode), the filter may have a frequency amplitude response characteristic to equalize the energy of the harmonic and fundamental frequencies to facilitate additional signal processing in the blocks that follow. The filter in this case may have a topology similar to a high pass filter, band reject or band pass filter depending on the signal path characteristics desired. The transmit/receive ASIC is preferably located within inches of the transducer elements, preferably in the same enclosure and just behind the transducer. The transducer array 210 and T/R ASIC 220 may be located in a separate module, such as a detachable scanhead, or incorporated into the main body of the diagnostic ultrasound instrument. If the scanhead is detachable, it may be connected to the main body through a cable, or through a wireless connection means.
Echoes received by the transmit/receive ASIC 220 are provided to the adjacent front end (FE) ASIC 230, which beamforms the echoes from the individual transducer elements into scanline signals. The FE ASIC 230 also controls the transmit waveform, timing, aperture and focusing. In the illustrated embodiment the FE ASIC 230 provides timing signals for the other ASICs, time gain control, and monitors and controls the power applied to the transducer array, thereby controlling the acoustic energy which is applied to the patient and minimizing power consumption of the unit. A memory device 232 is connected to the FE ASIC 230, which stores data used by the beamformer.
Beamformed scanline signals are coupled from the FE ASIC 230 to the adjacent digital signal processing (DSP) ASIC 240. The DSP ASIC 240 filters the scanline signals and also provides several advanced features including synthetic aperture formation, frequency compounding, Doppler processing such as power Doppler (Doppler/color power angio) processing, and speckle reduction. The DSP ASIC provides signal normalization, QBP RF filtering, programmable micro-code block and a compression/output filter. An external memory unit is connected to the DSP ASIC 240 for use in temporarily storing processed data. A secondary DSP block formed by an external field programmable gate array (FPGA) and DSP core 244 also connect to the FE ASIC 230 to provides the ability to perform Pulsed Wave (PW) Doppler as well as support M-mode analysis. A separate memory 246 provides necessary memory storage for the DSP ASIC operations.
The information from the various diagnostic modes performed in either the DSP ASIC 240, secondary DSP block 244, or the optional ECG external module (see below), are then coupled to the adjacent back end (BE) ASIC 250 for scan conversion and video formatting and the production of video output signals. A memory device 242 is coupled to the BE ASIC 250 to provide storage used in three-dimensional power Doppler (3D CPA) imaging as well as intermediate backend information. The BE ASIC 250 also adds alphanumeric information to the display 104 such as time, date and patient identification. A graphics processor overlays the ultrasound image with information such as depth and focus markers and cursors. Frames of ultrasonic images are stored in a video memory 254 coupled to the BE ASIC 250, enabling them to be recalled and replayed in a live Cineloop real time sequence. Video information is available at a video output in several formats, including NTSC and PAL for television formats and RGB drive signals for an LCD display 104 or a video monitor.
The BE ASIC 250 also includes the central processor for the ultrasound instrument, a RISC (reduced instruction set controller) processor. The RISC processor is coupled to the FE ASIC 230, DSP ASIC 240 and secondary DSP block 244 to control and synchronize the processing and control functions throughout the hand-held unit. A program memory 252 is coupled to the BE ASIC 250 to store program data used by the RISC processor to operate and control the unit. The BE ASIC 250 is also coupled to a data port 256. The data port 256 may be a PCMCIA interface, a USB port or other information I/O line. The interface allows other modules and functions to be attached to the hand-held ultrasound unit. The interface 256 can connect to a modem or other communications link to transmit and receive ultrasound information from remote locations. The interface can accept other data storage devices to add new functionality to the unit, such as an ultrasound information analysis package.
The RISC processor is also coupled to the user controls 110 of the instrument to accept user inputs to direct and control the operations of the hand-held ultrasound instrument.
The power for the hand-held ultrasound instrument is provided by a rechargeable battery. Battery power is conserved and applied to the components of the instrument from a power subsystem 280. The power subsystem 280 includes a DC converter to convert the low battery voltage to a higher voltage that is applied to the transmit/receive ASIC 220 to drive the elements of the transducer array 210.
Referring to FIG. 3, a block diagram of the DSP ASIC 240 is shown. Scanline signals from the FE ASIC 230 are received by a normalization circuit, where they are multiplied by a variable coefficient supplied by coefficient memory 308 to normalize the received signals for aperture variation. When the transducer is receiving signals along the scanline from shallow depths, a relatively small aperture, such as four or eight transducer elements, are used to receive echo signals. As the reception depth along the scanline increases, the aperture is incrementally increased so that the full 32 element is used at maximum depths. The normalization circuit will multiply the received scanline signals by appropriate coefficients over the range of aperture variation, such as factors of four or eight, to normalize the signals for this aperture variation effect.
When the ultrasound instrument is operating in the M mode to form a structural image of tissue and organs, the digital signal processor is operated as shown in the flow charts for M mode (FIG. 5). When the ultasound instrument is operating in the 2D mode the normalized echo signals follow two paths, as in FIG. 2, one of which is coupled to a four multiplier filter 312 and the other of which is coupled by a multiplexer 322 to a second four multiplier filter 314. Each multiplier filter includes a multiplier and an accumulator which operate as an FIR (finite impulse response) filter. Scanline echo signals are shifted sequentially into a multiplier, multiplied by coefficients supplied by the coefficient memory 308, and the products are accumulated in the accumulator at the output of the multiplier. The coefficients for the filter 312 are chosen to multiply the echo signals by a cosine function and the coefficients for the filter 314 are chosen to multiply the echo signals by a sine function, to form a quadrature bandpass filter (QBP), preparatory for I and Q quadrature signal detection in the micro-code block 324 on the I/Q pair. The four multiplier filters produce accumulated signals at a rate which is less than the input rate to the multipliers, thereby performing decimation band pass filtering. When the signal bandwidth exceeds the display bandwidth of the display monitor. The image lines will flicker due to an aliasing condition. The decimation filtering is designed to reduce the signal bandwidth as well as the data rate to match the display bandwidth of the monitor. By applying a succession of input signals and coefficients to a multiplier and accumulating intermediate products, the effective length of the filter can be increased. For instance, input signals 1-8 can be sequentially weighted by the fourth multiplier and the products accumulated in the fourth accumulator; input signals 3-10 can be weighted by the third multiplier and the products accumulated in the third accumulator; input signals 5-12 can be weighted by the second multiplier and the products accumulated in the second accumulator; and input signals 7-14 can be weighted by the first multiplier and the products accumulated in the first accumulator. The data rate has thereby been decimated by two, and each multiplier and accumulator is effectively operated as an eight tap filter. This it is seen that the effective number of taps of the filter is a product of the number of multipliers (four in this example) and the decimation rate (two in this example).
Additionally, this filter reduces r.f. noise and quantization noise through its bandwidth limiting effects. I and Q echo signal samples are produced at the outputs of filters 312 and 314, amplified if desired by the multipliers of gain stages 316 and 318, then stored in the r.f. memory 320. The Q samples are coupled to the r.f. memory by a multiplexer 326.
When a synthetic aperture image s to be formed the processing can be done in two manners, in the input RF domain after the normalizer block 310 or in the baseband domain after the QBP filter formed by 312 and 314. In the RF domain case the RF data points are stored from the first half aperture in r.f. memory 316 and added to the RF data points received from the second half aperture scanline. The resulting data is then filtered and processed in the normal manner as described above. In the Baseband case the I and Q samples after the QBP filter formed by 312 and 314 from the scanline of the first half of the aperture are stored in the r.f. memory 320 until the I and Q samples from the other half of the aperture are received. As the samples from the second half of the aperture are received, they are combined with their spatially corresponding counterparts by an adder (located in the micro-code 324). The size of this memory for the baseband case is kept to a minimum by storing the aperture signals after decimation filtering, which reduces the size of the memory required to store the scanline signal samples.
After the I and Q samples for the full aperture have been formed, the echo samples are analytically detected using the micro-code 324 and coupled to the compression circuit 328. The detected signal is compressed and scaled to map the detected signals to a desired range of display. Following detection and compression mapping, the signals are lowpass filtered in an FIR filter 332, then stored in an image frame memory 330. If the selected scanning mode (diagnostic mode) utilizes a single transmit focal point, the signals are transmitted back to the BE ASIC 250 for scan conversion. The signals can be frame averaged by an infinite impulse response (IIR) filter 336 in the Backend Asic which utilizes image frame memory 330 as a frame buffer. If multiple focal zones are used, each received scanline segment is stored in the r.f. memory 320 until scanline segments from the entire display depth have been received. Preferably the scanline segments for one complete focal zone are acquired before transmitting and receiving segments from another focal zone. When all segments for a scanline have been acquired, each complete scanline is then read out of the memory and filtered by the FIR filter 332 which smoothes the boundaries between the segments for a more pleasing, artifact free image. A flash suppressor 334 is used to eliminate large frame-to-frame variations in the display signals.
Time-motion analysis, or M mode follows the same path as 2D data as described above until the micro-code block. In M-mode the micro-code block 324 performs a filter on a set, 4-16 lines, of QBP filtered lines and decimates the resulting output to the display scroll rate. The data is then compressed in block 328 before the data is handed off to the secondary DSP 244 which handles the display process and interpolation to the desired number of pixels for the display. Once the interpolation and display handling is complete, the signal moves on to the BE ASIC 250 for normal output.
FIG. 4 illustrates a block diagram of the secondary DSP block 244 used for PWD mode. For PWD the QBP filter operations occur in a separate FPGA. In practice the operations of the external FPGA and secondary DSP can be combined in either a single ASIC, seperate ASICs or a combination of ASICs and off the shelf components, such as DSP cores or FPGAs. For this discussion it is assumed a separate FPGA is used to interface to the FE ASIC and perform the QBP filter operation while a DSP processor is used to perform the baseband processing after the QBP filter for PWD mode. As in 2D or M-mode the QBP filter 410 receives the r.f. signal from the FE ASIC and converts the signal into a baseband IQ pair. The Baseband pair are sent to the DSP processor. The IQ pair are wall filtered by using two 128 tap FIR filters. The wall filter 420 is used to reduce static or slow moving clutter from the signal. The Output of the wall filter is coupled to the Post Gain block 422 to apply gain to scale the post wall filter data appropriately for the next processing steps. At 424 a duplicate IQ pair goes to both the spectral path resampler 434 and the audio output path represented by 426, 430, 428, 432.
In the audio output 425 the IQ pair is processed to create a left and right channels of sound. The I signal goes to a Hilbert Phase Shifter prior to proceeding to the sum/difference blocks. The Q signal goes through a delay 430 prior and the sum and difference signals are generated to produce the left and right outputs. Both Left and Right outputs are amplified by the same audio gains 428 and 438 to send to the audio amplifier to drive the speakers.
In the Spectral path the IQ signals from the wall filter are coupled to the Resample block 434 to generate a IQ pairs at a 1 kHz rate. Every 1 ms N IQ pair enters the window block 436. N can vary depending on PRF rate and temporal resolution vs spectral resolution concerns. N typically will range between 64-256. The output of the window function is coupled to the complex fast fourier transform block FFT, which converts the signal from time domain to frequency domain. The frequency data is then coupled to the magnitude block 440 to generate the signed magnitude of the frequency output. The Frequency data is then averaged for smoothing effects and compressed in preparation for sending to the backend. The data next passes to the baseline shift block 446 to allow the display to be presented in a more effective manner for nonsymmetrical spectrums and finally the spectral data points are interpolated by 448 to the desired backend number of pixels for display. Additionally processing may also be done to generate the Peak and mean frequencies of the spectral data as shown in block 450. The additional information is also passed to the BE ASIC 250 for display on the scrolling display.
FIG. 5 illustrates an external ECG monitoring module that can be used with an ultrasound instrument of the present invention. The ECG module has three electrical leads for typical connection to a patient at the right arm, left arm and left leg (RA, LA and LL respectively). The connections to the right and left arms are used to measure the electrical potential across the chest during heart activity. The lead on the left leg is used as a reference as a signal. The electrical signals pass through the leads into the ECG module through an overload protection filter block 502. The block prevents any excessive potentials to damage the Differential Amplifier block 504 as well as filtering out of band energy to keep it from entering the circuit. The signals are then passed to the differential amplifier 504 for measurement of the electrical potential difference between the right arm and left arm lead using the left leg lead as a reference. The difference signal goes through a bandpass filter block 506 that eliminates signals outside the frequency range of interest and removes any DC offsets from the path up to that point. The signal is then coupled to the isolation block 508 which is necessary to protect the patient against risk of electrical shock hazard that might be present due to ground faults or other possible faults. The isolation block 508 may pass the signal across the isolation barrier 509 through an optical, magnetic or capacitive signal transmission means. The exact method of transferring data across the isolation barrier 509 is not particular to the present invention, as long as the method meets the ANSI/AAMI EC13 specification.
After passing through the isolation block 508, a highpass filter 510 eliminates resulting DC components or remaining low frequency energy and a first variable gain amplifier 512 can be used to boost the signal depending on the signal level. A lowpass/Notch filter 514 eliminates additional signal noise that may be present due to line frequency pickup (50/60 Hz and their harmonics) prior to moving to a second variable gain filter 516. The signal is then exported to the handheld ultrasound device 100 as either an analog signal 520, or a digital signal 522, after passing through an A/D converter 524. A user can control the gain of the signal from a gain control 136 in the handheld ultrasound device 100. The gain control 136 affects the signal both inside the hand held ultrasound device 100 in the image display unit 104, and at the two variable gain amplifiers 512, 516.
High pass filter 510 on the system side of the isolation block 508 removes the lower frequency component and biases from the signal isolation block output for the received ECG signal. It is a first order high pass filter 510 with a frequency cutoff set at 0.07 Hz. The signal from high pass filter 510 is then passed to a variable gain amplifier 512 that has a gain of from 1 to 8 with a center frequency at 100 Hz. The amplified signal from the variable gain amplifier 512 is then passed through a low pass/notch filter 514, having a center frequency of 30 Hz, and then to a second variable gain amplifier 516 with a gain of 1 to 8 and a center frequency at 50 Hz. The amplified signals are then exported to the handheld unit 100 as either an analog signal 520, or digital signal 522 through an A/D converter 524 within the system in unit 100 for application to and use by, the system processor.
In accordance with the present invention, power to the ECG electronics is applied through a power interface 542, which capacitively couples modulated power signals to amplifier 504. In specific embodiments, the DC power from the system can be either +16 volts or +9 volts. The power clock to interface 562 is received from the system in handheld unit 100.
The ECG module is either self powered using an isolated power supply, or powered from the main unit using a power subsystem and a isolated power generator so that only isolated power is fed to the elements on the patient side of the electrical isolation barrier.
FIG. 6 illustrates and example of a possible power scheme for an external ECG unit. The system power from the handheld unit is connected through serial connector inductors L1 and L2 to a first isolation capacitor C1. The common terminal of inductors L1 and L2 is connected via optional capacitor C3 and a transistor switch SW to the ground terminal of the system power. Switch SW is controlled in response to the power clock in chopping the system power at a frequency suitable for coupling through isolation capacitors C1 and C2 to the isolated electric circuit in module 500. The first coupling capacitor C1 is connected through a forward biased diode D1 to a positive charge storage capacitor C4, and isolation capacitor C1 is connected through a reverse bias diode D2 to a negative charge storage capacitor C5. Isolation capacitor C2 couples the system power ground to an isolated reference terminal.
The coupling capacitors allow for a very high frequency operation of the power interface. High frequency operation also allows the use of small capacitors and inductors on both sides of the isolation boundary, thus further reducing the size and weight of the ECG module. A resonant topology as shown also reduces EMI considerations since some switching voltage will be present on the isolated reference due to the capacitive coupling impedance of the ground planes and the switching currents circulating across the isolation boundary 509.
A high frequency operation is also required to allow the isolation capacitors to be small in value and guarantee the isolation impedance is sufficiently high to pass the energy required for the isolated power supplies without having the voltage present at the switching frequency on the isolated reference to fail the leakage current at that frequency. The allowed leakage currents increase with frequency.
The capacitors must be rated at a voltage which is large enough to pass the various safety tests, and rated at 5 kv or greater if defibrillation protection is desired. Surface mount capacitors are commercially available which must meet these requirements in a cost effective small and lightweight package. The use of capacitive coupling permits isolation of the power supply from the diagnostic system in accordance with medical safety applications.
Tissue harmonic imaging (THI) allows the reduction of signal clutter and near field effects. The normal 2D path components as described above are used for THI, but the blocks are programmed in a different manner. In THI the receive path QBP filter in block 312 and 314 will be programmed to receive energy at the second harmonic of the transmit spectrum. The Front End transmitters will be driven at a frequency near the low band edge of the transducer to allow the second harmonic energy to fall within the upper edge of the transducer frequency response. Some fundamental energy may also be utilized by shaping the QBP filter to fill out the image across the entire display depth due to the higher attenuation of the second harmonic energy with depth.
FIG. 7 illustrates an overview flow diagram of the license manager 1000 used in the present invention. Once the ultrasound instrument of the present invention is turned on, the system goes through its normal startup routine. During this procedure, the system checks for the operational mode of the device, established by a registry of gate flags. The gate flags identify to the system whether the unit is operating in unrestricted mode (normal mode) or a grade period mode (grace mode) as well as detecting the gate flags for the software that is enabled within the instrument. The principle gate flag is to determine if the operational mode is enabled as open (gate encoded as 1) or if the operational mode is encoded as "grace" (gate encoded as 0). If the operational mode is encoded as open, then the device operates in normal mode with the gate flag registry scanned so that all other diagnostic modes are scanned for a determination of whether the mode is enabled (gate flag set to 1) or disabled (gate flag set to 0). If the operational mode is set as "grace", the instrument will still run through a scan of the gate flag registry. Any enabled modes detected will now run in grace mode—they are available for use for a limited time as determined by the grace period. Once the grace period expires, those modes are disabled.
As shown in FIG. 10, the system goes through a startup routine 1002 when it is turned on. The system checks for the operational mode 1004, a gate flag set to either 1 or 0. If the operational mode 1004 gate flag is set to 1 (it is enabled), then the system enters unrestricted mode 1006. The system then proceeds to check for enabled application software or diagnostic modes 1008. Each diagnostic mode has a corresponding gate flag that is either set for 1 (enabled) or 0 (disabled). All the applications that are flagged as enabled are available to the user for normal use 1012.
If the unit detects the system is operating in grace mode 1020, the system checks the system clock against the preprogrammed grace period 1022. The grace period may be established in number of hours of run time for the system, number of hours of run time for a particular option, or number of hours since the grace period started (which would include time the system was turned off). Once the system has checked the grace period against the system clock, it will prompt the user 1026 to enter a keycode 1150 that will permit the unit to operate in normal mode 1012 without any additional prompts for a keycode. If the user enters a valid keycode 1150 and enables the unit for normal use 1012, the system will switch over from grace mode 1020 to normal mode 1012. If the user fails to enter a valid keycode, the system will either operate normally as long as the grace mode has not expired, or if the grace mode has expired, it will prompt the user to enter a valid keycode. If the user attempts to bypass the keycode entry screen, the unit will either shut down completely, or operate in a restricted normal mode where previously enabled applications are available to the user, however any "trial period" applications will not operate. A description of how the unit is enabled through the keycode licensing system follows.
FIG. 8 illustrates the keycode encryption algorithm utilized by the system in GOM. The algorithm shown is a combination of a signature generator 1104 and an encryption algorithm 1134 combined with a reversible logic operation 1110. In this process, a user selects one or more software features the user would like to enable in a programmable diagnostic ultrasound instrument. That information is provided to the manufacturer of the instrument, or their authorized agent. The software enabling request is converted into a code for entering into the keycode encryption algorithm. The code carrying the software enabling information becomes the options bits 1102 (containing some variable of K bits). Following the logic of the algorithm, the option bits 1102 are sent to a signature generator 1104 where the bit string is separated into a pair of sub-field bit strings, labeled J and L. An intact K option bit string is sent to a merge operation 1106 that merges the K bit string with the J bit string into an N bit word. The N bit word is then sent to a circular shift 1108 (which may be any bit shift process, but here is labeled a left shift) wherein the shift is equal to L bits. The circular shifted N bit word becomes a first N bit string 1130 and is passed on to the reversible logic process 1110 (X-or operation shown here).
A second N bit string 1132 is generated using information specific to the instrument to be upgraded. This information involves parameters unique to the particular device, such as a device ID 1122 (serial number or other identifier), software build ID 1124, or other identifier assigned to the instrument during the manufacturing of the device. The unique device identifiers are combined with one or more secret constants 1120, 1126 (two in the example shown) and the unique identifiers and secret constants are used as the encryption keys for a block encryption algorithm 1134 (TEA, or others). To generate the necessary output bits for the reversible logic operation 1110, a bit pattern constant may be utilized in the block encryption algorithm. The encryption algorithm 1134 executes its logic on the input of the various encryption keys and optional bit pattern constant 1140 to produce a second N bit string 1132. The second N bit string 1132 is sent to the reversible logic process 1110 for a creation of a third N bit string 1136. The third N bit string 1136 is processed through a merge shift count 1112 using the L bit sub-field produced in the signature generator 1104. The result is a N+L bit string that is converted into a keycode 1150 of alphanumeric (or simply numeric) characters. Since the characters coded for in the keycode 1150 may use a large number of bits, the keycode 1150 can be relatively short while the N+L bit string is very long.
While either alphanumeric or simple numeric keycodes can be generated, there are practical limitations to an alphanumeric keycode. An alphanumeric keycode (keycode) cannot be easily distributed to foreign countries where the language base does not support the same alphabet as the manufacturer or authorized agent of the ultrasound instrument. For the manufacturer, an alphanumeric scheme may be used domestically, or in countries with a common alphabet. However for location where the product is used where the alphabet is not the same, a simple numeric keycode must be used. In either case the length of the license will still provide the use of the full length of the N+L bit string.
The logic shown utilizes a single signature generator 1104 and a single block encryption algorithm 1134. However the effectiveness of this type of keycode generation system is by no means limited to using only one of each type of algorithm. Computationally a processor can as easily handle a keycode generation system that involves a plurality of signature generators and encryption algorithms. The base component that is required regardless of the combination of algorithms used is to provide for the reversible logic operation to mix the bits of the various bit strings that are produced so that it is essentially impossible for an unauthorized person (e.g. some one trying to hack the ultrasound software) from enabling features in the instrument which have not been paid for, and cannot be tracked as required by government regulations. Thus the use of the encryption algorithm as a pseudo-random number generator, combined with a signature generator to produce an option string with a series of non-option encoding bits, combined with the reversible logic (X-OR) process, permits the generation of a strong, safe way to transmit a license code through any channel which cannot be decrypted by an unauthorized user. The use of this process allows the device to recover all the necessary option bits upon reversing the procedure.
FIG. 9 illustrates the process through which the keycode is verified by the ultrasound instrument implementing security mechanism of the present invention. The keycode 1150 generated (FIG. 11) in the license generator 1100 is entered into the instrument by a user at the new license entry prompt 1018. The keycode of P characters 1150 encodes the N bit word and the L bit string from the license generator. The instrument has the same logic operations programmed into it as are used in the license generator (FIG. 11) and is able to extract L bit string and the N bit word from the P character keycode 1150. The N bit word 1136 is used by a reversible logic process 1110 (X-or) to reverse the logic process of the license generator. The second N bit string 1132 that was originally produced by the block encryption algorithm 1134 is produced by an identical operation within the ultrasound instrument. The second N bit string 1132 is used with the N bit word 1136 in the reversible logic operation to reproduce the first N bit string 1130.
From this point the L bit string extracted from the keycode 1150 of P characters is used to extract the relevant signature bits, error detection bits and option bits. By using the reversible logic process 1110 and the combination of a signature generator 1104 and block encryption algorithm 1134, it is possible to extract a large number of bits from a small number of characters in the keycode. The various bit patterns must match up precisely to produce the signature, error detection bits and option bits 1102. The option bits 1102 are then used to identify which gate flags of the system registry are to be marked "open" or "closed" thus enabling previously dormant software resident in the ultrasound instrument.
In conjunction with the keycode system of the present invention, the ultrasound device may have a software application made available to a user through uploading through an external hardware element, such as a detachable scanhead. This is particularly useful when a new feature requires a new hardware element such as a specialized scanhead (e.g. for neonatal examinations) or a specialized diagnostic module (such as an ECG attachment). In this instance the software application is automatically loaded from the scanhead (or attachment) to the main ultrasound unit 100. The unit detects the new scan head either at startup, or during a peripheral device check routine. When the new scanhead is detected, the system automatically detects software that is not already part of the software library. The new software is download from the scanhead into the main software library and enabled for use during a fixed grace period. The customer is permitted to try the software during the grace period and enter a keycode specific to the software downloaded from the scanhead. In the event a valid key is entered into the ultrasound instrument the grace period switches over to unrestricted use, and the user is able to use all functions that have been paid for without any concern for running out of the trial period. However if the proper keycode is not entered into the ultrasound instrument, the ultrasound instrument will not startup as normal during the start up procedure (at the expiration of the grace period). Instead the ultrasound instrument will automatically prompt the user for the proper, unit specific keycode that will allow the unit to be used in unrestricted format. If the user fails to enter the proper code, the ultrasound instrument will automatically go re-prompt the user for a keycode. Alternatively the unit might be programmed to shut down, or enter a "sleep" mode. Use of information specific data to a particular unit permits the proper unit to be enabled with the desired features. Use of the same keycode on another unit will not generate an authentication bit string. This insures that each keycode issued by the manufacturer prevents the enablement of features on a different unit. It also permits the manufacturer to maintain a precise database of the capabilities of each instrument since each instrument may only be upgraded through a keycode made available from the manufacturer. Although the instrument itself has the ability to verify a keycode, it does not have the ability to generate keycodes on its own, and the unique elements to each instrument would not permit some one to "hack" one instrument to yield a security scheme to enable other instruments of the same type. It is also possible for the user to contact the vendor for a license code that will disable the application that has placed the instrument into the GOM and return to unrestricted use of the previously purchased applications without enabling any new features.
While the processes described above are principally executed through software, an alternative embodiment of the present invention utilizes the same operations within the program of an application specific integrated circuit (ASIC) wherein the ASIC chip retrieves the necessary input values to perform the logic of producing and verifying a keycode or keycode from one or more registers containing the necessary information. In this manner the ASIC mimics the same logic as the software previously described to achieve the same result. The ASIC may be programmed with additional features such as a feature verifying download to a keycode database in order to enable or disable any applications within the software library.
FIG. 10 illustrates a system incorporating the license generator and an ultrasound instrument of the present invention. The system incorporates a general purpose computer 1306 having a license generator 1100 for receiving the required information from a user necessary to create a keycode 1150. Once an operator has entered the necessary instrument specific information provided by a client, a keycode 1150 is produced that is provided to the client. The transmission means of the keycode to the client can be in any format, including a public distribution since the keycode has no value to anyone except the client. The vendor may receive the request through a dial-up connection using a modem M or through an internet connection LAN, or the user may call the vendor by phone 1302 and the vendor can manually input the information into the keycode generator. The client then enters the keycode into the unit for which the upgrade is desired. The instrument runs through the decryption process to produce the first N bit string and validates the keycode. Once the keycode has been validated, the instrument 100 now operates with the desired features. The vendor or manufacturer can update his records in his central database 1304 with the newly enabled features of the ultrasound instrument 100 allowing the manufacturer to maintain a complete and accurate log of all the instruments sold and their operational capabilities. Using this system the manufacturer is able to keep accurate records of the capabilities of all the instruments sold. The manufacturer may be the same entity as the vendor, or the vendor may perform the keycode generation and report the information back to the manufacturer.
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The basic properties, methods of characterization, applications, and safety issues of nanoparticles are described in Masuo Hosokawa et al. (eds.), Nanoparticle Technology Handbook (2007). The design, assembly, and use of nanoparticles as semiconductors, scaffolds, chemical sensors, catalysts, and other agents is covered in Vincent M. Rotello (ed.), Nanoparticles: Building Blocks for Nanotechnology (2004). The specific application of nanoparticles in the development of drug-delivery technologies is described in Ram B. Gupta and Uday B. Kompella (eds.), Nanoparticle Technology for Drug Delivery (2006). Nanoparticle safety, from their manufacture and handling to their use in biomedical technologies, is discussed in Thomas J. Webster (ed.), Safety of Nanoparticles: From Manufacturing to Medical Applications (2009). Issues surrounding the behaviour and detection of nanoparticles in the environment are discussed in Kevin J. Wilkinson and Jamie R. Lead (eds.), Environmental Colloids and Particles: Behaviour, Separation and Characterisation (2007). The consequences to the environment and to human health as a result of the introduction of human-made nanoparticles are discussed in Ron E. Hester and Roy M. Harrison (eds.), Nanotechnology: Consequences for Human Health and the Environment (2007).
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Adorable 'McGhees' too nice for reality TV
Adorable 'McGhees' too nice for reality TV
The McGhees are a delightful family. Is it wrong to hope their show flops?
The reality show genre, which is famous for bringing out the worst in people, takes another swing at sextuplets with "Six Little McGhees," cutie pies in Columbus, Ohio.
Grade: C
Parents Mia and Rozonno were high school sweethearts. He says he was instantly smitten. She might have needed some convincing, but the way they tease and support each other now says enough.
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An investigative officer who presided at a hearing to help decide whether three midshipmen should face court-martial over a sexual assault allegation has forwarded his recommendations to the school's superintendent, the academy's spokesman said Monday.
Lawsuit Filed In Naval Academy Sex Assault Case
Attorneys for a midshipman at the center of a sexual assault case against three ex-Navy football players have asked in a federal lawsuit filed Thursday that the Naval Academy's superintendent not be involved in the decision of whether the men will be court-martialed.
Naval Academy Sex Assault Case Continues
A U.S. Naval Academy midshipman accused of sexually assaulting a fellow student initially told a Navy investigator that he hadn't interacted with her at a party, but he changed his story in a later interview to say he had sex with her, the investigator testified Sunday.
Naval Academy Sex Assault Hearing Postponed A Day
A military hearing on sexual assault accusations against three U.S. Naval Academy midshipmen has been postponed because the alleged victim says she is too fatigued to testify.
Hearing Begins For Naval Academy Football Players Accused Of Sex Assault
Facing a judge. Three Navy football players are in military court, accused of raping a female midshipman at a 2012 off-campus party and then lying about it.
Naval Academy Grad Says Top Brass Needs To Stop Sexual Assaults
The military is under fire for what's being called an epidemic of sexual assault.
Police Release Sketch Of Suspect Who Sexually Assaulted 7-Year-Old
Police have released a sketch of the man who sexually assaulted a young girl.
Police: Woman Sexually Assaulted At Knifepoint While Jogging In Fells Point
A downtown community is on edge after an unusual attack right along the Fells Point waterfront. A female jogger was sexually assaulted early Friday morning. And now, the suspect is still on the loose.
Baltimore Police Investigate Sex Assault On Notre Dame Campus
Baltimore City police are investigating a sex assault that happened on the Notre Dame campus.
Prince George's County Deputy Sheriff Accused Of Sexual Assault
A deputy sheriff in Prince George's County is accused of sexually assaulting a female inmate inside the county courthouse.
New Sex Assault Case Linked To Serial Rapist
A 1996 sexual assault has been linked through DNA to the same man believed responsible for nine other attacks on women in the District of Columbia and Maryland, police and the FBI said Thursday.
Annapolis Police Release Surveillance Video Related To Downtown Sexual Assault
Annapolis police are looking for the man who sexually assaulted a downtown resident last month.


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Took the family to the meet the Hall
Of Famers who were in attendance this weekend. WOW. Total class acts. Every players ask my boys if they played ball and what position. Leo was the best. He told my oldest to eat cereal this morning before his tournament game and to stay away from bacon and eggs. Lee May was friendly and told the Hall people to relax when they tried to push us through. Eric Davis still looks like he could play. Sean Casey was very personable and thanked us several times for attending. George Foster flirted with my wife and pushed me out of the picture Loved seeing the guys I grew up watching. The Hall of Fame did a tremendous job and the players proved why I am a die hard REDS FAN FOR LIFE.


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Lions Eye Institute Limited
|Lions Eye Institute Limited Patent applications
|Patent application number
|TREATMENT OF AMD USING AAV SFLT-1 - The present disclosure provides compositions and methods for the prevention or treatment of ocular neovascularization, such as AMD, in a human subject, by administering subretinally a pharmaceutical composition comprising a pharmaceutically effective amount of a vector comprising a nucleic acid encoding soluble Fms-related tyrosine kinase-1 (sFlt-1) protein to the human subject.
|Therapeutic molecules for modulating stability of vegf - This present invention discloses nucleic acid compositions and methods that are useful for treating ischemic conditions in animals, particularly in mammals such as humans. Specifically, the invention discloses nucleic acid molecules comprising or encoding a sequence that modulates the stability of a transcript from a vascular endothelial growth factor gene, as well as pharmaceutical compositions containing such molecules, which arm useful for modulating angiogenesis or vascularization, especially in methods for treating ischemic conditions.


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Date: 1 year ago
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There are many things I understand but do not do myself for erotic stimuation. I have seen people use sounds, catheters, and needles but this is extreme. I am glad he is using what appears to be sterile technique but the risk of infection in a non-sterile enviroment is too great. Good luck - I have no idea what you could possibly do next to feed your fetish.
What is he doing?
This has to be one of the more fucked up things I've ever seen. Wow.


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Staff Reporter
The order says schools should spend 95 p.c. of earning on improving standards
NELLORE: The All-India Youth Federation (AIYF) has asked the Government to implement its order with regard to primary education (GO 1 of 1994 ) in letter and spirit.
The GO, which stipulates that all school managements should spend 95 per cent of their earnings only to improve academic standards, has been kept in abeyance for a variety of reasons.
"The time has come now for the Government to implement the order with a view to checking private school managements from commercialising education in the State," AIYF State council general secretary G. Eswaraiah told reporters on Thursday.
Moreover, the Government should also take private school managements to task for violating norms on many fronts besides initiating action against all those District and Mandal Education Officers, who failed to check managements from collecting donations from parents. "Parents face problems arranging for donations," he said.
The AIYF decided to stage dharnas at all district collectorates in the State on June 30 demanding filling of 2.5 lakh vacancies. The AIYF leader alleged that the Congress had failed to implement its election manifesto and unemployed youth were the most affected in the three-year Congress 'misrule'. He wondered as to why the unemployment dole promised for jobless youth in the Congress manifesto had not yet been implemented in the State.
Protest plan
The AIYF would conduct classes for its activists from June 23-27 in Hyderabad. It would also lay siege to all AP Vaidya Vidhana Parishad offices in July demanding quality medicare for common man. The federation would also conduct 'cycle jata' in September and cover 1,400 km to highlight various issues, Mr. Eswaraiah added.


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Logan, located at the south end of the Cache Valley against the Wasatch Range and the dramatic Wellsville Mountains to the west, is an attractive Western-style college town, well known for its scenic beauty and recreation. It is home to Utah State University and a center of Mormon culture and history. The economic base extends well beyond the university; a diverse set of businesses have discovered the area's pleasant surroundings, good labor force, and low operating costs. Industries include high tech, biomedical research, food processing, printing and call centers with names like Pepperidge Farms, Moore Business Forms, Herff-Jones (yearbooks) Convergys and Tyco present.
The downtown area is attractive and walkable with wide streets and independently owned businesses, spreading mostly east into the hills with traditional homes, trees, and several parks. Cost of living is reasonable for the type of area and crime rates are extremely low, but geography makes Ogden and especially Salt Lake City to the south a fairly long trip at 75 miles across a mountain pass and may be difficult at times in winter.
The Cache Valley is flat and dry and mostly grassland or agricultural. Logan is tucked into the south end of the valley with wooded mountains rising on three sides and especially to the south. The climate is generally dry and pleasant with lots of sun, warm days and cool evenings in summer, with infrequent rain arriving mostly as thundershowers. Winter is mostly dry and fairly mild with a few blasts of rigorous weather each year, bringing snow, a few below-zero days, and a dusting to a moderate accumulation of snow.
As of 2014, Cache County's population is 112,095 people. Since 2000, it has had a population growth of 22.65 percent.
The median home cost in Cache County is $190,500. Home appreciation the last year has been 0.60 percent.
Compared to the rest of the country, Cache County's cost of living is 1.90% Higher than the U.S. average.
Cache County public schools spend $7,182 per student. The average school expenditure in the U.S. is $12,435. There are about 23 students per teacher in Cache County.
The unemployment rate in Cache County is 2.50 percent(U.S. avg. is 6.30%). Recent job growth is Positive. Cache County jobs have Increased by 2.91 percent.
Ranked #4 Emerging Metropolitan AreasRanked #5 Most Secure Places to Live in the U.S. (Small Towns)Ranked #6 Most Secure Places to Live 2011 (Small Towns)Ranked #99 Best Green CitiesSee More Rankings Click Here
Average Commute time is 17 minutes. The National Average is 25 minutes.
Cache County's Real Estate Market (click to see properties) • Newly Listed Homes • Most Expensive Listing • Million Dollar Houses • Homes from $750,001 to $1,000,000 • Homes from $500,001 to $750,000 • Homes from $250,000 to $500,000 • Homes under $250,000 • Median Priced Homes
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Best of Hot Dish: June 10-14, 2013
|Benjamin Carter Grimes
|Booze-soaked beer and tasty wings from Mason's
The Twin Cities food and drink scene keeps on rockin'. Stay in the know with the top stories from this week's Hot Dish.
~We have a "Drink of the week" from Smack Shack that you can sink your teeth into.
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How can I tail the running cron job, so that I can come to the conclusion that my job is going on.
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In your script you could echo something like
If you want to check 'live' what your job is doing, just do
Another option is to log the start (or the end) of your script in syslog with the
You need to find out the PID of your job:
After that you can check if your job is working, by tracing its actions with


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Fed Begins Sales of Treasuries Under Operation Twist
Oct. 12 (Bloomberg) -- The Federal Reserve began selling as much of $9 billion of Treasuries as part of its program to replace $400 billion of short-term debt in its portfolio with longer-term Treasuries in an effort to reduce borrowing costs.
The central bank is offering securities maturing from March 2013 to October 2013 for sale between 10:15 a.m. and 11 a.m. New York time, according to a Federal Reserve Bank of New York statement today.
The Fed will purchase $44 billion of longer-maturity Treasuries and sell the same amount of shorter-term debt in October under a monetary stimulus plan that's become known as Operation Twist.
To contact the reporter on this story: Liz McCormick in New York at firstname.lastname@example.com
To contact the editor responsible for this story: Dave Liedtka at email@example.com


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The draw of Silicon ValleyComment
Aitoro interview April 30, 2015
CIA to undertake sweeping change of spy agency
Possible capture of ISIS leader's wifeComment
Green interview December 3, 2014
House intel panel debunks many Benghazi attack theories
Apple's new payment systemComment
Verton intverview September 18, 2014
Brain FoodComment
We read a lot about how healthy eating can save our hearts and our waistlines. But what about our brains?
The NSA ReviewComment
Leighton interview December 18, 2013
The NSA decisionComment
Mahoney interview December 17, 2013
Changes at the National Security AgencyComment
Jackson interview October 21, 2013
Who is Edward Snowden? NSA leaker comes forwardComment
Edward Snowden grew up in Ellicott City, Md. He said he knew the great risks he was taking in exposing a phone records monitoring program and an Internet scouring program designed by the government to monitor for threats.
Sequestration could hurt American intelligence effortsComment
Budget cuts due to sequestration could have a major negative effect on how well the United States can gather and process intelligence, Federal Times reports.
Osama bin Laden dead: Inside the raid that killed bin LadenComment
When helicopters descended out of darkness on the most important counterterrorism mission in U.S. history, they were acting based on years of intelligence work that eventually led to bin Laden.
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ABC7 News at 4 Now Weekdays!ABC7 is giving you MORE news in your afternoons with an extra hour, an hour earlier! Join ABC7's Leon Harris and Alison Starling for what's trending in your community and world. Every weekday afternoon at 4pm right after back to back "Hot Bench" shows at 3pm on ABC7.


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"What sort of contradictory justice is this? How can one court find him guilty another find him not; even though his misdoings are known to everyone," questioned the father of the budding tennis player, who was allegedly molested by the former Haryana Director-General of Police S.P.S. Rathore in 1990.
The teenager committed suicide three years after the incident.
On Wednesday, the Central Bureau of Investigation (CBI) stated in a report submitted to an Ambala court that the charges against Rathore could not be proven and subsequently on Thursday he was granted bail by the Supreme Court.
The Supreme Court took into consideration the fact that Rathore had already completed six months of his 18-month conviction and the CBI filed two closure reports on Wednesday in two of the three fresh cases filed against Rathore by the victim's family.
Last December, three fresh first information reports were registered against the former police officer after a public outcry on the six-month sentence he received. The jubilant manner in which he walked out of the court premises also caused a lot of resentment. However, the CBI challenged the verdict in a session's court in Chandigarh which enhanced the sentence to an 18-month jail term.
"2 FIRs registered"
Two FIRs were registered against Rathore for non-bailable offences such as attempt to murder, criminal intimidation, forging evidence, wrongful confinement, fabricating false evidence, custodial torture and criminal conspiracy. In its closure report, the CBI claimed that the allegations could not be proved on the basis of documentary evidence and the oral testimony of witnesses alone. While the CBI filed the closure reports in two cases before a special magistrate here, the probe in the abetment-to-suicide case has been stayed by the Punjab and Haryana High Court.
On May 25, the Chandigarh sessions court enhanced Rathore's sentence to 18 months, terming the initial verdict as an 'error' and denied bail to avoid 'mockery of justice delivery system.' The judge had observed that "the convict has no remorse for the wrong committed by him… Every witness of this case had to face allegations in one form or the other and attempt was made to catch them in a well-woven legal web."
The victim's father said that he or his family were never questioned by the CBI. "We had provided the statement of witness and all the evidence that were required in court, but they could not find any proof. No one approached us for any questioning or proof. How can they claim that charges against him for his heinous acts could not be substantiated?"
Reacting to the CBI's report, he said, "The closure report will not give any relief to Rathore as abetment-to-suicide charges are still intact. We will pursue the legal course of actions and I am sure that Rathore will get strict punishment for his crime."
To be challenged
The victim's family friend, Anand Prakash, who fought the case for over two decades, said that an independent inquiry should be formed to ensure that no police officers were involved in the probe. "Needless to say, the CBI has shielded him. We will challenge the CBI move on November 25 in the Ambala Court.
"Throughout the inquiry, the CBI was inclined towards favouring Rathore and his officers. The CBI is shielding the accused. We had apprised the Union Home Ministry of our apprehension and will demand an independent inquiry where no police officers are involved in the investigation," Mr. Prakash said.
Rathore,69, is currently serving his 18-month sentence in the high-security Burail jail in Chandigarh for molesting the teenager.


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Sharing is easy: With Verizon, you get a link to a Web site where you can view the video. With the new iPhone 3GS, you can e-mail the video to yourself or use SMS to send it to other phones (There are also apps to upload directly to Facebook and YouTube). With the T-Mobile MyTouch, we could e-mail, message or upload video to the Web directly through the phone.
Video cameras from the likes of Sony and Canon cost a lot, but they deliver big. I tested a Canon Vixia hard drive-based HFS10 and the Sony HDR-HC9 Mini-DV camera. These types of camcorders are priced at $750 and up, and while they are heftier than the Flip or the Kodak, they are still just a little bigger than a soda can. They have flip-out LCD screens, a microphone input, and they take still pictures. These cameras have a big advantage over the shoot-and-share cameras like the Flip: They have 10X optical zoom.
Prosumer camcorders have very sophisticated lenses that can physically magnify images. If you shoot sports or nature scenes, this is important. The shoot-and-share cameras don't have this kind of zoom.
The image sensors in prosumer cameras also handle motion much better than the shoot-and-share cameras. Prosumer cameras pan smoothly and you don't see motion blur in action shots. While the Kodak Zi8 does have a microphone input, most low-end cameras don't. If you care about recording comments from people at noisy events (weddings, parties, restaurants) or doing serious storytelling with interview subjects, you will want to invest in an external microphone. People underestimate the importance of good sound, but it is one of the most important elements of making your videos meaningful.
The downside of these powerful cameras is their complexity. Only the owner of the camera will feel comfortable picking up the device to record a moment, so less video is captured. Getting videos onto your computer is easier than it used to be with these types of cameras, but it's still much more complicated than if you were just dragging and dropping files from a Flip cam.
I am the mom of two toddlers and I've been in the TV business for 16 years, so I know my way around cameras. I have a $2,000 camera here at the house and I have a few Flip cams. Ninety-five percent of the time, I record the kids with the Flip cam. When I create videos for ABCNews.com or need to capture home video for "GMA," I use my prosumer camera.
When I've wanted to do interviews with family members to preserve our stories and history, the clear choice is the prosumer camera. I'm a jock, and when I've been asked to record games for analysis, I always use the prosumer camera. When I've been out on the road and seen the kids do something cute, I record it with my phone.
Bottom line: Most people only need to invest in a shoot-and-share Flip Cam or Kodak Zi8, and if more sophisticated video needs arise, only then consider the $1,000 plus investment in a prosumer camera.


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These figures provided by the CNN-IBN exit poll predictions clearly indicate that the BJP is going to be victorious in these 3 states. In all 3 states the BJP vote share is increasing by a considerable percentage.
In Haryana, according to the CNN-IBN exit poll predictions-the BJP-HJC is projected to win about 38% of the vote share which is a jump from 22% in 2009.Congress is to fall to 24% vote share in 2014 from a 42% in 2009.Indian National Lok Dal to jump from 16% in 2009 to 20% in 2014.AAP will be at a meager 4% vote share.
The BJP seems to winning the majority share in this state.
In Uttarakhand, the contest is predicted to be a straight fight between the BJP and Congress.BJP jumps to a whopping 49% in 2014 from 34% in 2009. Congress which won all 5 seats in 2009 fell to a vote share of 38% from 43% in 2009.BSP falls to only 7% from 15% vote share in 2009.
Himachal Pradesh, a traditional seat for the BJP,it is to remain stable at a 51% vote share and it had 50% in 2009.Congress to fall to 37% from a 46% in 2009.


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Hey grapple fans it's the Great Blueski again... this blog is about the thoughts I had for the evolution of TNA. Now bear with me because I started this blog a few weeks if not a month and a half ago and abandoned it cos I had some boxing ish to talk about elsewhere on the web (it's been a funny few months in the boxing world wrestling fans... Pac Man was screwed worse than the Rock at Wrestlemania
This is the Great Blueski blog. And this time I'm going to talk about but the man who rules the world (as the title of the blog probably already gave away lol)... SID!!!
So I was watching old tapes the other day and I came across Wrestlemania 8. We're talking the golden era of the Great Blueski's childhood here. The double main event Savage vs Flair for the gold and Sid vs Hogan
© 2011 eWrestlingNews, All Rights Reserved.


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Mon-Fri: 7am-1am EST / Sat-Sun: 7am-11pm EST
ApplianceRoper Washer
Level of DifficultyEasy
Time to do repair15 - 30 mins
Age of Appliance5 - 10 years
Screw driversSocket set
0 out of 3 people found this instruction helpful
Bottom Agitator was working, but top part wasn't. It was running ok, but not cycling the clothes from top to bottom.The repair was fairly simple. I took the cap off the center, and down inside was a domed looking disk with an O ring on it. I turned it a little to unseat it, and it came right out. I used a Socket wrench with an 11mm socket and multiple extentions to reach down to the bolt. When I took out the bolt, the whole thing comes out. I got the top agitator piece, it needed one. the repair kit, it needed this also. And a thrust washer that I did not need. The kit came with a thrust washer, and I didn't know it. The washer only cost $2 and something, so I didn't worry about it to much. Had all the instruction, with pic's, so it was no problem to replace. Anyone with a little mechanical know-how will breeze through it.
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Part Number: PS334562
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Home » Girls' Swimming & Diving News
BSW: Dragons 2nd on Senior NIght
February 11, 2014By Andrew Smith of New Palestine High School
New Palestine recognized its swimming seniors Monday, finishing second in the final boys meet of the regular season.
Pendleton Heights won the meet with 145 points. New Palestine tallied 124 and Hagerstown 37 in the three-way meet at NPHS.
New Palestine recognized its seven swimming seniors -- Carl Baird, Chris Dodd, Grant Gish and Kelley Murphy from the boys team, and Claire Hornsby, Tricia Roberson and Addison Virt from the girls team.
New Palestine's Jake Mitchell, Chris Dodd, Kelley Murphy and Todd Horn won the 200 medley relay.
Todd Horn was also part of two second-place finishes -- in the 100 freestyle and joining Grant Gish, David Thompson and Jake Mitchell on the 400 free relay.
"Todd Horn really looked strong last night, swimming a couple of life-time bests and anchoring a relay with a great finish. I think he'll be one of our guys to surprise other schools at sectional."
Also second were Murphy in the 200 IM, Gish in the 50 freestyle, Conner Page in diving, Mitchell in the 100 backstroke and the 200 medley relay team of Page, Luke Reed, Joey Rogers and Parker Horn.
"This was a 'last chance' meet for some of the guys as final decisions about the sectional line-up were being made," NP coach Steve Maxwell said. "We had some really good performances and it helped to clarify what our sectional will look like."
"It's been a rough winter and our training has been so erratic; but, after seeing how well the girls swam at their sectional last weekend, the guys are optimistic they will do equally as well. We'll put in another week of regular workouts and then begin to rest the boys for sectional."
The New Palestine boys swimming sectional will be held Feb. 20-22.


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My video review of Zack Zero - It's surprisingly good.
By mkernan 1 Comments
Zack Zero just hit the Playstation Store this week (and last week on the EU store). I had never even heard of the game prior to its launch, which seems to typically only happen with pretty terrible games. I hadn't even heard of the developer either, but it turns out Crocodile Entertainment is a small development team based in Spain and this is their first release.
I have to say, I was pretty impressed with the game, even moreso considering the fact that it seemed to complete appear out of nowhere. Check out the video below for my review of Zack Zero. If you like what you see, the game is available now on the PlayStation Store for $12.99.


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Urban Assault
Don't try this at home people! Urban Assault displays utility poles and phone lines with three guys repelling down them with shades of grey and yellow. This urban shirt makes you want to go for an adventure!
Urban Assault
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E-book to open doors to Myanmar
Published on Dec 15, 2012 6:00 AM
THE gates of the once-reclusive Myanmar have swung open, but what is happening inside remains a bit of a mystery.
Is the opening up for real? Is the much talked about economic boom for real? And what does the man in the street make of it? Questions swirl even as Yangon makes great strides in dismantling controls that have held the country back.
Chances are that you are already invested in the Myanmar story - the world's newest democracy experiment and the region's last great economic frontier.
Perhaps you are intrigued by the unlikely torch-bearer in President Thein Sein, or captivated by the understated glamour of the serene Ms Aung San Suu Kyi.
Maybe the entrepreneur in you sees Myanmar as the next Asian tiger. Is it a window of opportunity for you? Or, if you plan to sample the unspoilt charms of the Golden Land, what should you pack before you go?
The Straits Times brings you "Myanmar Sunrise" - downloadable on your iPad from early next month.
The Straits Times' Indochina Bureau Chief Nirmal Ghosh and a select team of writers and insiders will capture the story of Myanmar's awakening in this interactive book. You will find essays by ST Foreign Editor Ravi Velloor, ST Life! writer John Lui and loads of pictures and videos by prize-winning photographers Sim Chi Yin and Neo Xiaobin.