text:
The FABP2 gene encodes for the intestinal FABP (IFABP) protein, which is expressed only in intestinal enterocytes. A polymorphism at codon 54 in exon 2 of the FABP2 gene exchanges an Alanine (Ala), in the small helical region of the protein, for Threonine (Thr). Given the potential physiological role of the Ala54Thr FABP2 polymorphism, we assess in this study the local population frequency and analyze possible associations with five selected markers, i.e. glycemia, total cholesterol, body mass index (BMI), hypertension, and high Cardiovascular Risk Index (CVR index).
We studied 86 men and 116 women. DNA was extracted from a blood drop for genotype analysis. Allele frequencies were calculated by direct counting. Hardy Weinberg Equilibrium was evaluated using a Chi-square goodness of fit test.
For the polymorphism association analysis, five markers were selected, i.e. blood pressure, Framingham Risk Index, total cholesterol, BMI, and glycemia.
For each marker, the Odds Ratio (OR) was calculated by an online statistic tool.
Our results reveal a similar population polymorphism frequency as in previous European studies, with q = 0.277 (95% confidence limits 0.234–0.323). No significant association was found with any of the tested markers in the context of our Argentine nutritional and cultural habits. We did, however, observe a tendency for increased Cholesterol and high BMI in Thr54 carriers.
This is the first study to look at the population frequency of the Thr54 allele in Argentina. The obtained result does not differ from previously reported frequencies in European populations. Moreover, we found no association between the Thr54 allele and any of the five selected markers. The observed tendency to increased total cholesterol and elevated BMI in Thr54 carriers, even though not significant for p < 0.1 could be worth of further investigation to establish whether the Thr54 variant should be taken into consideration in cardiovascular prevention strategies.
Fatty acid-binding proteins (FABPs) are small intracellular polypeptides found in many tissues, involved in fatty acid transfer and metabolism [1] and encoded by a family of different genes. The FABP2 gene encodes intestinal FABP protein (IFABP), and is only expressed in the absorptive simple columnar epithelial cells of the intestine (enterocytes) [2]. Several functions of IFABP protein have been proposed, these include the facilitation of cellular uptake and/or transport of long-chain fatty acids within enterocytes [3]. The IFABP protein contains two beta-sheet structures surround a cavity into which the ligand binds [4]. The major conformational adjustment between the structure of free IFABP and IFABP bound to fatty acid, occurs at a tight turn containing residues 54 and 55. These residues shift position when long-chain fatty acids are bound to the protein. Therefore, even a subtle change in the amino acid sequence of this turn could affect the structural properties of IFABP in such a way as to alter its ligand affinity [5].
A polymorphism at codon 54 in exon 2 of the human FABP2 gene exchanges an Alanine (Ala) in the small helical region of the protein for Threonine (Thr). Different studies suggest that the Ala-to-Thr substitution is in fact a functional mutation [6,7]. It is reasonable to speculate that if the FABP2 gene polymorphism in any way modifies the absorption of fatty acids, it could in turn affect the lipid metabolism and/or correlate with cardiovascular disease (CVD) risk. Earlier studies have shown that the IFABP Thr54 allele is significantly associated with higher total cholesterol, with stroke incidence [8], elevation of fasting and postprandial triglyceride [9], insulin resistance [2,6], and higher nonesterified fatty acid (NEFA) concentrations [10]. There are many contradicting studies, however, that have found non-significant association with these parameters [11-14]. In the light of the potential physiological role of the FABP2 polymorphism, we assessed the local population frequency of the Thr54 allele and analyzed its possible associations with five selected markers, i.e. glycemia, total cholesterol, body mass index (BMI), hypertension and cardiovascular risk index (CVR index). Our results reveal a similar population polymorphism frequency as in previous European studies and a not significant association with none of the tested markers in the context of our argentine nutritional and cultural habits.
We recruited 202 volunteers (mean age 53 years) from various Public Administration Offices, including 86 men (aged between 35 and 75 years, mean age 51) and 116 women (aged between 45 and 75 years, mean age 56). The means in the sample were: cholesterol level 198,34 (190,52 for men and 204,27 for women), diastolic blood pressure: 79,38 (82,93 for men and 76,96 for women), systolic blood pressure: 127,22 (131,15 for men and 124,26 for women) and BMI: 28,45 (28,86 for men and 28,13 for woman). In the 202 subjects, there were only 11 diabetics. On receiving written informed consent from all participants included in this population screening study, a drop of blood was collected for total cholesterol and glycemia analysis using commercial kits (Accu-Chek Instant Plus, Roche Diagnostic). A second drop of blood was collected on a DNAase free paper (Nucleic Paper, Biodynamics S.R.L, Buenos Aires, Argentina) for DNA extraction. Systolic and diastolic blood pressure was measured by a physician. BMI was calculated as weight (kg) divided by height squared (m2). The ethical committee of the Public Health Care Program for Government Employees (OSEP, Obra Social del Empleado Publico) approved the study.
Cardiovascular risk assessment by calculation of the Framingham Risk Index
The cardiovascular risk was calculated for each individual by the Framingham Index according to the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III guidelines [15]. This index takes into account the following variables: sex, age, blood pressure, total cholesterol, HDL and smoking status. The HDL measure was excluded from this study because of its low impact on the total score for the risk calculation. The total score was obtained by summing the partial scores for each of the variables mentioned. The total score of 10 was established as the threshold, with a 0 to 9 total score implying low risk status and a 10 or higher total score implying high risk status.
Genotype analysis
To extract DNA, a piece of 2 mm radio was cut out from the blood drop on DNAse free paper, added to 100 μl sterile water, and then incubated for 30 minutes at 95°C. For PCR reaction 10 μl were used. Some DNA samples which did not amplify well were diluted 1:10 or 1:20.
DNA was amplified in a total volume of 20 μl, with the upstream primer: 5'ACAGGTGTTAATATAGTGAAAAG3' and the downstream primer: 5' TACCCTGAGTTCAGTTCCGTC3' [6]. The PCR program consisted of an initial and final hold of 94°C and 72°C for 3 minutes, and 30 cycles of 94°C, 55°C, and 72°C, with each step of 30 seconds duration.
For Restriction Fragment length Polymorphism (RFLP) analysis, 5 μl of PCR product were incubated with 0.4 μl of enzyme CfoI (GCG/C) (10 U/μl, Promega) in a final volume of 10 μl for 1 hour at 37°C.
The products were run on a 10% non-denaturing PAGE for 50 minutes at 110 V. Bands were observed after Ethidium bromide staining and UV light exposure.
Allele frequency and polymorphism association analysis
Allele frequencies were calculated by direct counting. Hardy Weinberg Equilibrium was evaluated using a Chi-square goodness of fit test.
For the polymorphism association analysis, five markers were selected, i.e. blood pressure, Framingham Risk Index, total cholesterol, BMI, and glycemia. Each parameter was assigned a threshold value, established by the RCP Program, as follows:
1-Hypertension >140 mmHg systolic or >90 mmHg diastolic; 2-Framingham Risk Index >9 total score; 3-BMI >24 kg/m2; 4-Total cholesterol > 240 mg/dl; 5-Glycemia >110 mg/dl after 8 h fasting or >140 mg/dl postprandial.
For each marker, the Odds Ratio (OR) was calculated by the online statistic tool [16].
The Thr54 allele frequency in Argentina
To assess the polymorphism frequency in our region, DNA samples of 202 individuals (86 men and 116 women) were analyzed for the Ala/Thr polymorphism. The included subjects belonged to an ongoing Regional Cardiovascular Prevention Program (RCP program), organised by the Public Health Care Program for Government Employees (OSEP) of Mendoza (Argentina). This programme focuses on the assessment of an individual cardiovascular risk index in order to apply prevention strategies in the analyzed population.
The observed population genotype composition was: 105 Ala/Ala homozygous, 82 Ala/Thr heterozygous and 15 Thr/Thr homozygous (Table 1).
Table 1. Genotype analysis in the study subjects
Eventhough the province of Mendoza has a total population of almost 1.600.000 individuals, it presents a non-homogenous population distribution provoked by the migration of families to the surroundings of the capital city of Mendoza. We therefore decided to carefully analyze our genotype composition results in order to detect whether our sample could be affected by endogamic behaviour. The cluster of inhabitants around the city could lead to inbreeding and consequently reduce the number of observed homozygous, and affect the allele frequency. In order to assess whether this was interfering with our population sample, the amount of observed heterozygous and homozygous for the Ala54Thr polymorphism was used in the formula F = He-Ho/He (where He and Ho are expected and observed heterozygous). However, a negative (-) 0,02 inbreeding rate was found, confirming there is no endogamic behaviour in our population that could have affected the allele frequency.
The calculated Thr54 allele frequency was q = 0.277 (95% confidence limits 0.234–0.323). In a subsequent analysis of the equilibrium of the populations genotypes, the results revealed that the proportion of hetero and homozygous did not differ significantly from the expected genotypes for a population in Hardy Weinberg equilibrium (Table 1) (p > 0.05, Chi squared goodness of fit), which is consistent with our first finding of non-endogamic behaviour.
The assessment of the polymorphism frequency in Argentina with similar values as in European countries [17] encouraged us to subsequently analyze possible genotype-phenotype associations.
Polymorphism association analysis reveals no significant impact on CVD risk markers
For the genotype-phenotype association assessment, the phenotypic information of the 202 individuals included in the study was used. Association analysis with allele Thr54 was performed on five selected parameters, i.e. glycemia, total cholesterol, BMI, hypertension, and cardiovascular risk (calculated by the Framingham Risk Index). Comparisons were performed between subjects that carried at least one Thr54 allele (homozygous Thr/Thr and heterozygous Ala5Thr) and non-carriers of the allele Thr54 (homozygous Ala/Ala). For each parameter, a threshold value was established by the RCP Program (see Methods).
Our study reveals no significant association (p > 0.05) between the Thr54 allele and any of the analyzed parameters (Table 2). The ORs represent the magnitude of association between the genotype and disease, consequently ORs with a 95%CI including the value 1 are indicative of no difference between Thr54 carriers and non-carriers for that factor. We analysed the five markers in male Thr54 carriers respect to female Thr54 carriers. We did not find any significant difference (for p = 0,05) between gender for BMI, cholesterol, blood pressure, and glycemia.
Table 2. Association analysis of the Thr54 polymorphism and phenotypic parameters
These results are in accordance with other previous publications that found no major contribution of allele Thr54 on these phenotypic parameters [11-14].
Despite the non-significant association results, we consider it worth noting that the ORs for Cholesterol (2.01), BMI (1.44) and CVD risk (1.25) are >1. When we analyzed the distribution of Thr54 carriers and non-carriers combining two of these three parameters, we observed an increased number of polymorphism carriers with high cholesterol and high BMI (Figure 1). Notice in Figure 1a that the quadrant corresponding to high cholesterol and high BMI shows more carrier individuals (17/97) than non-carriers (10/105). This not significant difference for p < 0.1 but subtle tendency was not observed in the rest of the parameter combinations that were analyzed (data not shown). These results reveal that even though the markers for Cholesterol and BMI do not show a significant association with the polymorphism when they are analyzed on their own, a subtle tendency is observed when they are analyzed in combination.
Figure 1. Association of Thr54 carriers with the combination of markers: i.e. cholesterol, BMI and cardiovascular risk index. Sample distribution for Thr54 carriers (homozygous Thr/Thr and heterozygous Ala/Thr) and non-carriers (homozygous Ala/Ala) regarding two features: (a) BMI and Choslesterol (b) Cardiovascular risk index (CV Risk) and Cholesterol. (c) Cardiovascular risk index (CV Risk) and BMI. The crossing lines show the threshold values for BMI (24 kg/m2), cholesterol (220 mg/dl), and high risk (9 total score)
There are no previous reports about the prevalence of the Thr54 FABP2 variant in our region. In the sample tested, the observed Thr54 frequency (q = 0,277) is similar to that reported in eleven different European countries (0.276) [17], suggesting that the colonising European populations, mainly from Italy and Spain, introduced the same original allele frequency in this continent and that this frequency has remained conserved. The fact that the proportion of carriers has not changed and that the polymorphism is in a Hardy Weinberg equilibrium suggests that there is no significant natural selection pressure acting against individuals with the Thr54 FABP2 variant living in Mendoza, Argentina. Other South American frequency analysis of Thr54 were reported by a Chilean group, who found a q = 0.4 in 63 obese and not obese women [18], and a Brazilian study that reported a q = 0.25 in 1042 diabetes type 2 individuals [19]. Even though both analyses are performed on specific study sample, i.e. obese and diabetic individuals, the Brazilian frequency in 1042 individuals is similar to that observed by our group in Argentina.
It is well known that the single nucleotide polymorphism (SNP) at codon 54 is a missence variant that has a definite effect on the primary structure of the protein and affects its fatty acid binding properties. It is not known, however, whether this change can affect the lipid metabolism of carriers [20]. Many earlier studies have reported associations between this polymorphism and insulin resistance, BMI, dyslipidemia, stroke, metabolic syndromes and hypertriglyceridemia [2,6,8-10,21-23]. In contrast, other studies report no association with the same parameters [11-14]. Part of the discrepancy among the studies may come from the different dietary habits of the analyzed populations. For example, the lack of association found in a Finnish population [24] could be related to its prevailing fish diet where the Thr54 variant may not cause any phenotypical manifestation. Therefore, it was important to assess some of these associations in Argentina, characterized by the consumption of significant amounts of beef (i.e. 68 kg of beef/year/habitant). This diet is rich in proteins and fats and poor in fibres and fish [25]. In addition, it was relevant for the local RCP Program to develop health prevention strategies based on educational programs of life style and nutritional habits.
Our results indicate that in the assessed population, the allele Thr54 does not influence the glycemia levels nor the blood pressure (odds ratio approaching 1).
The Cholesterol levels, BMI and CVR index are not significantly influenced by the Thr54, but show ORs >1. These tendencies for increased risk are better manifested when BMI and Cholesterol are analysed in a combination. This observation does, however, not prove association or causality. The sample size was small, and these observed tendencies require further investigation in order to reveal whether the influences become significant and whether it could be related to the meat and fat-rich diet prevailing in Argentina.
We present the first study investigating the Thr54 allele frequency in Argentina and its association with five cardiovascular risk markers. The population frequency of the Thr54 allele in Argentina does not differ from previously reported frequencies in European populations. Moreover, we found no association between the Thr54 allele and any of the five selected markers. Although the observed tendency for increased total cholesterol and elevated BMI in Thr54 carriers was not significant, this will require further investigation to establish whether the Thr54 variant should be taken into consideration in cardiovascular prevention strategies in our country.
Competing interests
The author(s) declare that they have no competing interests.
Authors' contributions
LCG performed the DNA sampling, the molecular assays, the frequency analysis, the phenotypic association studies and the revision of the manuscript. SMR contributed to the DNA sampling and the genotyping experiments. MSO provided the original idea and the PCR primers set. SG is the head of the RCP Program. LSM advised on the design of the study, on the experimental work, and on the critical revision of the manuscript. MR developed and guided the project and drafted the manuscript. All authors read and approved the final manuscript.
This work was supported by the Public Health Care Program for Government Employees (OSEP, Obra Social del Empleado Publico) Mendoza, Argentina.
Hsu KT, Storch J: Fatty Acid Trasfer from liver and Intestinal Fatty-bindig Proteins to Membranes Occurs by Differents Mechanisms.
J Biol Chem 1996, 271:13317-13323. PubMed Abstract | Publisher Full Text
Weiss EP, Brown MD, Shuldiner AR, Hagberg JM: Fatty Acid binding protein-2 gene variants an insulin resistance: gene and gene-environment interaction effects.
Physiol Genomics 2002, 10:145-157. PubMed Abstract
Berthier MT, Couillard C, Prud'homme D, Nadeau A, Bergeron J, Tremblay A, Depre's JP, Vohl MC: Effects of the FABP2 A54T Mutation on Triglyceride Metabolism of Viscerally Obese Men.
Obesity Research 2001, 9:668-675. PubMed Abstract | Publisher Full Text
Rajabzadeh M, Kao J, Frieden C: Consequences of single-site mutations in the intestinal fatty acid binding protein.
Biochemistry 2003, 42:12192-12199. PubMed Abstract | Publisher Full Text
Zhang F, Lucke C, Baier L, Sacchettini JC, Hamilton JA: Solution structure of intestinal fatty acid binding protein: Implications for ligand entry and exit.
Journal of Biomolecular NMR 1997, 9:213-228. PubMed Abstract | Publisher Full Text
Baier LJ, Sacchettini JC, Knowler WC, Eads J, Paolisso G, Tataranni PA, Hisayoshi M, Bennett PH, Bogardus C, Prochazka M: An amino acid substitution in the human fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation and insulin resistance.
Baier LJ, Bogardus C, Sacchettini JC: A polymorphism in the human intestinal fatty-acid-binding protein alters fatty acid transport across Caco-2 cells.
J Biol Chem 1996, 271:10892-10896. PubMed Abstract | Publisher Full Text
Carlsson M, Orho-Melander M, Hedenbro J, Almgren P, Groop LC: The T54 Allele of the Intestinal Fatty Acid-Binding protein 2 is associated with a parental history of stroke.
J Clin Endocrinol Metab 2000, 85:2801-2804. PubMed Abstract | Publisher Full Text
Georgopoulos A, Aras O, Tsai MY: Codon-54 polymorphism of the fatty acid-binding protein 2 gene is associated with elevation of fasting and postprandial triglyceride in type 2 diabetes.
J Clin Endocrinol Metab 2000, 85:3155-3160. PubMed Abstract | Publisher Full Text
Pratley RE, Baier L, Pan DA, Salbe AD, Storlien L, Ravussin E, Bogardus C: Effects of an Ala54Thr polymorphism in the intestinal fatty acid-binding protein on responses to dietary fat in humans.
J Lipid Res 2000, 41:2002-2008. PubMed Abstract | Publisher Full Text
Galluzzi JR, Acupples L, Meigs JB, Wilson PW, Schaefer EJ, Ordovas JM: Association of the Ala54-Thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the Framingham Offspring Study.
Diabetes Care 2001, 24:1161-1166. PubMed Abstract | Publisher Full Text
Endo K, Yanagi H, Hirano C, Hayakawa Y, Hamaguchi H, Tomura S: No association found between the Ala54Thr polymorphism of FABP2 gene and obesity and obesity with dyslipidemia in Japanese schoolchildren.
Pihlajamaki J, Rissanen J, Heikkinen S, Karjalainen L, Laakso M: Codon 54 polymorphism of the human intestinal fatty acid binding protein 2 gene is associated with dyslipidemias but not with insulin resistance in patients with familial combined hyperlipidemia.
J Clin Endocrinol Metab 2002, 87:3735-3739. PubMed Abstract | Publisher Full Text
Erkkila AT, Lindi V, Lehto S, Pyorala K, Laakso M, Uusitupa MI: Variation in the fatty acid binding protein 2 gene is not associated with markers of metabolic syndrome in patients with coronary heart disease.
Nutr Metab Cardiovasc Dis 2002, 12:53-59. PubMed Abstract
National Cholesterol Education Programme (NCEP) Adult Treatment Panel (ATP) III guideline [http://www.nhlbi.nih.gov/guidelines/cholesterol/atglance.pdf] webcite
Pedro Confidence Interval Calculator[http://www.pedro.fhs.usyd.edu.au/calculator.html] webcite
Tahvanainen E, Molin M, Vainio S, Tiret L, Nicaud V, Farinaro E, Masana L, Ehnholm C: Intestinal fatty acid binding protein polymorphism at codon 54 is not associated with postprandial responses to fat and glucose tolerance tests in healthy young Europeans. Results from EARS II participants.
Atherosclerosis 2000, 152:317-325. PubMed Abstract | Publisher Full Text
Albala C, Santos JL, Cifuentes M, Villaroel AC, Lera L, Liberman C, Angel B, Perez Bravo F: Intestinal FABP2 A54T polymorphism: association with insulin resistance ana obesity in women.
Canani LH, Capp C, Ng DPK, Choo SGL, Maia AL, Nabinger GB, Santos K, Crispim D, Roisemberg I, krolewski AS, Gross JL: The fatty acid binding protein 2 A54T polymorphism is associated with renal disease in patients with type 2 daibetes.
Diabetes 54:3326-3330. PubMed Abstract | Publisher Full Text
Agren JJ, Valve R, Vidgren H, Laakso M, Uusitupa M: Posprandial lipemic response is modified by the polymorphism at codon 54 of the fatty acid-binding protein 2 gene.
Arterioscler Thromb Vasc Biol 1998, 18:1606-1610. PubMed Abstract | Publisher Full Text
Hegele RA, Harris SB, Hanley AJ, Sadikian S, Connelly PW, Zinman B: Genetic variation of intestinal fatty acid-binding protein associated with variation in body mass in aboriginal Canadians.
J Clin Endocrinol Metab 1996, 81:4334-4337. PubMed Abstract | Publisher Full Text
Guettier JM, Georgopoulos A, Tsai MY, Radha V, Shanthirani S, Deepa R, Gross M, Rao G, Mohan V: Polymorphisms in the fatty acid-binding protein 2 and apolipoprotein C-III genes are associated with the metabolic syndrome and dyslipidemia in a South Indian population.
J Clin Endocrinol Metab 2005, 90:1705-1711. PubMed Abstract | Publisher Full Text
Vimaleswaran KS, Radha V, Mohan V: Thr54 allele carriers of the Ala54Thr variant of FABP2 gene have associations with metabolic syndrome and hypertriglyceridemia in urban South Indians.
Metabolism 2006, 55:1222-1226. PubMed Abstract | Publisher Full Text
Rissanen J, Pihlajamäki J, Heikkinen S, Kekäläinen P, Kuusisto J, Laakso M: The Ala54Thr polymorphism of the fatty acid binding protein 2 gene does not influence insulin sensitivity in Finnish nondiabetic and NIDDM subjects.
Diabetes 1997, 46:711-712. PubMed Abstract
Navarro A, Diaz MP, Munoz SE, Lantieri MJ, Eynard AR: Characterization of meat consumption and risk for colorectal cancer in Cordoba, Argentina.
Nutrition 2003, 19:7-10. PubMed Abstract | Publisher Full Text
Pre-publication history
The pre-publication history for this paper can be accessed here:


text:
Join our mailing list to be the first to learn about new opportunities
Keshet sometimes has internship openings.
We seek motivated interns who are interested in building community for LGBT Jews and organizing for change. We welcome applicants from all religious backgrounds, gender identities, and sexual orientations and are looking for interns with the following skills and qualities:
To apply for an internship, please send a resume and cover letter explaining why you would like to intern with Keshet to: Richard Feczko.

subset: commoncrawl


text:
Less power to cell phones, more power to the people
The IndiGo pay-as-you-go energy solution (Photo: Eight19)
Researchers are developing innovative ways to keep smartphones powered-up in the developing world (Photo: Shutterstock)
Article Summary
Smart phones are techno wonders, and they are also energy guzzlers, which is not a problem for people living in the developed world. However, their high energy requirements has stymied the adoption of mobile internet services in developing countries where mobile internet can be a real lifeline. In Africa, for example, few people can access the internet from a wired connection but 90 percent of the population lives in areas with mobile phone network coverage. There's one problem though. Access to the power grid in Africa is limited.
« Back to Less power to cell phones, more power to the people
Other Images from this Gallery
Related Articles


text:
News from WTOP
News from the AP
Mike Causey
Shows & Panels
Shows & Panels
- Agency of the Month
- Business of Government Hour
- The CFO Agenda: Delivering value from financial transparency and audit efforts in the public and private sector
- Cloud-Driven Data Insights in Government
- CXO Surveys
- Disaster Resilience for America
- Federal News Countdown
- Government Perspectives on Mobility and the Cloud
- Reducing Risk in the Cloud
- Reimagining the Next Generation of Government
Shows & Panels
- AFCEA Answers
- American Readiness: Renewable Power and Efficiency Technologies
- Ask the CIO
- The Business Case for Cloud Computing in Government
- Cloud-Driven Data Insights in Government
- Connecting the Dots: Digital Authentication in Government
- Cybersecurity Game Changer: Real-Time Event Processing in Government
- Data-Centric Approaches to Government in the Cloud
- Delivering the Digital Government Mission
- Federal Executive Forum
- Federal News Radio's National Cyber Security Awareness Month Special Panel Discussion
- Federal Tech Talk
- The Future of Government Data Centers
- Government Perspectives on Mobility and the Cloud
- Industrialized, Interoperable and Insight-driven Federal Health Panel
- Innovation and Tech Superiority through Acquisition Reform
- Mitigating Insider Threats in Virtual & Cloud Environments
- Moving Agency Applications to the Cloud with PaaS
- Reducing Risk in the Cloud
- Security in the Age of Targeted Attacks
- Air Traffic Management Transformation Report
- The Business of Cloud
- Cloud First Report
- Data Driven Cloud Series
- Disaster Resilience for America
- General Dynamics IT Enterprise Center
- Gov Cloud Minute
- Government in Technology Series
- Homeland Security Cybersecurity Market Report
- The Intersection: Where Technology Meets Transformation
- Modern Mission Critical Series
- National Cybersecurity Awareness Month
- The New IP for Federal IT
- The Social Platform Solution for the Department of Veterans Affairs
- Technology Insights
- The Cyber Security Report
- The Next Generation Cyber Security Experts
Shows & Panels
- Cloud-Driven Data Insights in Government
- Disaster Resilience for America
- F-35 Lightning II Program
- Government Perspectives on Mobility and the Cloud
- On DoD
- Pentagon Solutions
- Reducing Risk in the Cloud
- Reimagining the Next Generation of Government
- Transforming Business Operations at the Defense Department
SEC uses cloud to organize case files
Tuesday - 8/31/2010, 2:30pm EDT
The Securities and Exchange Commission is using cloud to organize case files. Their previous system was 10 years old, and staff had to use phone calls, emails and the U.S. mail to keep up with their work.
Now, federal CIO Vivek Kundra says, much of that has changed.
the SEC implemented a cloud-based CRM tool called Salesforce.com. The implementation of Software as a Service (SaaS) solution that took less than 14 months from inception to deployment. Since the implementation of OIEA, the SEC has realized improvements in system reliability, efficiency and accuracy. Paper files are scanned into the system and worked electronically. All investor contact channels (email, web-form, US mail, fax, and phone) are brought into a single queue to be assigned and worked electronically. All documentation can now be attached to case files, which allows staff member to build complete chronology of events. Using this new paperless environment, the time required to complete files has significantly been reduced.
Read more of the case study here.


text:
For Sale: 1966 Pontiac GTO
Convertible 389 Trip Power
Ad #182228574 Posted:2015-02-10 07:40:37
This ad expired 78 days ago.
Up for sale we have a 1966 Pontiac GTO Convertible. This is a real GTO with the 242 Vin Code as well as the PHS Docs. It has a lot going for it with the Drop Top along with the '66 model 389 Tri Power, Steering, Brakes, and Air. When you look down the sides it has great lines with good gaps. The panels are straight as an arrow. Everything is covered in Cameo Ivory, the factory color, which has a good shine and shows well. It is accented by the Blue Top and pin stripping. The stainless looks good and the bumpers appear to have been either replaced ore rechromed. The final exterior touch is the set of Blue Wall Tires Mounted on a set of Factory Rallye Wheels. Everything on the inside is done in Blue, the factory color, which is an excellent complement to the exterior. It has the correct seats and console. A set of aftermarket gauges were added under the dash and a tach was added to the console. It appears that the seat covers and carpet were replaced at the time of the resto. The top is Power and comes with the Blue boot. Under the hood it has a '66 Model 389 that has the Tri Power Set Up 3x2's. It's mated to the 350 Turbo Trans with the stock 10 Bolt Rear End. The engine retains the stock manifolds and dual exhaust. It comes with Power Steering and Power Brakes. As we said it is a factory AC car that is all there and works. The floor in this GTO are great and super solid with what looks to be the factory pans. Also the Frame looks good with no signs of any damage. If we can help you in any way with questions or a specific picture, you can call our office at (865)988-8088. Or feel free to call Daniel at (423) 807 0600, Devvin at (865) 256 2366, or you can e-mail us at firstname.lastname@example.com.
Business Phone Number: 8659888088
This item is USED
Trades ACCEPTED
Item Location: MARYVILLE, TN Get Directions To This City
This item is USED
Trades ACCEPTED
Item Location: MARYVILLE, TN Get Directions To This City
Business Information
Ad posted by:
Ad posted by:
smokymnttraders (#191178)
Smoky Mountain Traders
2520 S Carver Rd
Maryville, TN 37801
(865) 988-8088
Member Since: 2007-05-02
Phone Number: 8659888088
Member Feedback
Number of Honor Payments: 0
Average Accepted Sale Price: $0.00
Average Honor Payment: $0.00
- Ad #182496086: 1971 Oldsmobile 442
- Ad #182496091: 1970 Dodge Challenger
- Ad #182496094: 1970 Plymouth GTX
- Ad #182496104: 1970 Chevrolet Chevelle
- Ad #182496105: 1970 Chevrolet Chevelle
Report the sale - click here


text:
Tablet. Hotels for Global Nomads
Travel Better.
Tablet Plus
Mondrian South Beach
1100 West Avenue, Miami Beach, FL, USA
Neighborhood: South Beach
With the Collins Avenue strip on the Atlantic side of South Beach pushing maximum density, it makes a certain kind of sense that the Morgans group's next move would be to set up shop on the Biscayne Bay side. For one thing, it affords a bit of space to spread out: with over three hundred units, many of them privately owned, the Mondrian South Beach isn't exactly modest.
Who better to assume the mantle of Morgans' resident design genius—previously worn by a certain Philippe Starck—than the Netherlands' maximalist man-of-the-moment Marcel Wanders? He's a natural fit, both for Miami Beach and for the Mondrian; his bright and shiny modern-baroque sensibility is a natural next step for this white-on-white Art Deco town.
It's a classic boutique-hotel pleasure palace, with all that that entails: bustling bars, placid pools, and a dream of a dining room. Guest rooms lack for nothing in the way of luxury, and the spa, also by Wanders, is a good deal sexier than the usual zen-and-exfoliation fare. Don't be afraid of West Avenue; while it's uncharted territory at the moment, the Mondrian will change that — and anyway, you're close enough to the rest of the South Beach action that you'll be thankful for this slight remove at the end of the night.
- Complimentary upgrade upon hotel check-in, based upon availability
- One complimentary welcome drink per guest at Sunset Lounge (this is in addition to the welcome drink already included in the resort fee)
- Guaranteed 2pm. late check out
- Complimentary continental breakfast for two (tax and service not included)
- 335 Rooms
- Style: Modern Design
- Atmosphere: Happening
- 80 Guest Reviews
- Mondrian South Beach
- 1100 West Avenue
- Miami Beach, FL, USA
- Neighborhood: South Beach
Hotel amenities and services
- 100% non-smoking hotel
- 24 hour concierge
- 24 hour front desk
- 24 hour gym
- Bar
- Bicycle rentals nearby
- Boardroom
- Business center
- Central air conditioning
- Golf nearby
- Lounge
- Multi-lingual staff
- No pets allowed
- Outdoor swimming pool
- Restaurant
- Sauna
- Self service parking (charges apply)
- Shopping area nearby
- Spa
- Valet parking (charges apply)
- Wake-up service
- Wi-fi (charges apply)
Other Miami hotels
80 Guest Reviews
All reviews are from Tablet guests with verified stays.
- robert
- Stayed December 2013
- Rating: Good
What I liked:
Great location. Make sure to get a bay view balcony terrace. Worth the price.
What the hotel could do better:
Nothing, had a wonderful stay!
- Ronanne
- Stayed October 2013
- Rating: Excellent
What I liked:
Loved the pool and view
What the hotel could do better:
Nothing, had a wonderful stay!
- Michael Keith
- Stayed April 2013
- Rating: Good
What I liked:
location, cleanliness, staff
What the hotel could do better:
update pool chairs


text:
|Page: 1 of 1
|Sort By:
Bed & Breakfasts Cascais, Portugal - This jewel of a property is located right in the middle of the picturesque and cosmopolitan town of Cascais, 30 km outside Lisbon on the Estoril Coast
Find a bed and breakfast in Cascais Portugal for your romantic weekend getaway. Intimate b & bs are cozy, romantic accommodations that are perfect for a mini-vacation, honeymoon, or wedding anniversary celebration. You will love the unique charm of our inns in Cascais Portugal. Many guesthouses include complimentary breakfasts and unbeatable hospitality. Browse our bed & breakfasts and plan your Cascais Portugal romantic getaway today!


text:
Cheap BFI to Decatur flights
Popular Flights from Seattle, Washington
Top Seattle Flights to US Destinations
Top Seattle International Destinations
Popular Flights from Decatur, Illinois
Top Decatur Flights to US Destinations
BFI to DEC Route Map
Seattle to Decatur Flights, Stats and Airplanes
Route information for flights from Boeing Field to Decatur IL.
1,737.75 miles
BFI - Boeing Field Airlines
Browse the most popular airlines servicing the Seattle (BFI) airport. Visit their flights pages to learn more about the most popular routes these carriers fly.


text: Slideshows Published On: Jul 06 2012 04:51:34 PM EDT Updated On: Feb 19 2013 05:06:31 PM EST On this day: May 24 Test your Memorial Day knowledge Before they were famous: Celebrity commercials Sky 10 above scene as naked man sits atop Fort Lauderdale drawbridge 7 pains men should never ignore Top 10 U.S. beaches of 2015 On this day: May 23 On this day: May 22 10 superfoods for spring Celebrities who served in the military Who is ISIS? New pets awaiting adoption Where are 'Blossom' stars today? Notable deaths of 2015 Indianapolis 500 time trials, Carb Day Baby born in BSFR truck Neki Mohan Through The Years PHOTOS: Fans celebrate Miami Heat championship Test your hair band IQ Police: Insurance fraud ring leaders busted New pets awaiting adoption PHOTOS: Dolphins Friday practice Horse racing's Triple Crown winners Calvin Hughes Through The Years Janine Stanwood Through The Years Tractor-trailer crash blocks southbound traffic on I-95 Police: 27 homeowners busted for insurance fraud A Day In The Life Of Janine Stanwood Gratigny Plateau Park's opening day speakers PHOTOS: White hot Heat fans View More


text:
Ortlieb Mudracer LED Seat Pack
It's a seat pack that's waterproof, it holds two tubes, a multitool, a puncture repair kit and some coins...
Ortlieb Mudracer LED seat pack
It's a seat pack that's waterproof, it holds two tubes, a multitool, a puncture repair kit and some coins, it fits easily to the saddle with the use of two Phillips head screws, there's a removable inner pocket, it has a quick release mechanism and a Velcro strap for around the seat tube to stop it rattling.
That pretty much covers every seat pack I've ever used, so why should you buy this one? Well, as stated above this one is waterproof, made so by the cunning use of a stretchy rubbery plastic (transparent silicone) clear cover that folds down around the zip. For the rubber fetishists out there this does have a certain touchy feely thing going on – its tempting to keep folding the flaps up and down, but then the looks you get from passersby soon put a stop to this.
Another more practical reason to buy this is the inbuilt red LED light, it has standard flashing and full on modes, it's easy to switch on and off and of course it means you'll never forget to fit a rear light for those dark night time training rides.
The pack is available in two sizes and is a useful addition to any bike but especially any bike that is just used for everyday rides where you just need to go without thinking, you'll never get caught short.
Review by Steve Makin
Categorised as:
Posted on: June 17, 2010
You Might Like…
7 responses
looks quite cool. what are the rough dimensions? is the grey bit hard plastic?
i have the one without a light and it is really good. I wish i had got this version though as i can then only fit a light really low down on the seatpost where it cannot be seen so well.
"Avaliable in 2 sizes"
Which size is this one? It carries exactly what I need so it would be good to know which version this is.
yes, the grey plastic is hard, and to be honest I really cannot remember which size it was, sorry !
Is the light any good? What sort of batteries does it use, and how long do they last?
yes, no idea, no idea
Sizes 0.7lt and 1.0lt, from the Ortlieb website http://www.ortlieb.co.uk/product_info.php?pName=mudracer-led&cName=bike-saddlebags
Also few more details here (2 year old review, but looks identidical) http://road.cc/content/review/982-ortlieb-mudracer-seatpack
Log in with your Premier account to comment
If you already have a website account, log in.Forgotten your password?
Not got a Premier account?
Subscriptions cost as little as £2.99 and include access to our entire MagArchive


text:
Wilkes to use attorney for the indigent at trial.
"Wilkes to use attorney for the indigent at trial."
Contractor Brent Wilkes, who was charged with "fraudulently obtaining millions of dollars in government contracts" in the Duke Cunningham scandal, "will have an attorney paid for by taxpayers." Prosecutors from the U.S. Attorney's Office protested that Wilkes should not be allowed to have an attorney that represents the indigent, "noting that the defense contractor is believed to have greatly profited from his alleged crimes."


text:
LITTLE ROCK, Ark (KTHV) - The Pulaski County School District's request to be declared substantially desegregated has been denied by a federal judge.
The district will remain under federal court supervision for now, but US District Judge D.P. Marshall said he's open to holding hearings on the matter next fall.
Superintendent Doctor Jerry Guess said they're encouraged by the judge's decision. "That is our goal -- to regain unitary status in the district so that there are no vestiges of segregation. And to return to the funding stream that is the same for all districts in Arkansas," he explained.
Judge Marshall asked the district to file a status report by February, providing more information on being unitary in areas such as student assignment and special education.
The North Little Rock and Little Rock districts have already been declared unitary.


text:
|Community Calendar
|Upcoming Past Month View
Here you can find out about upcoming events and view photo galleries of past events. Some events may allow for online registration and the ticket purchase. Click the event name to view more details.
CEU: Medical Qigong Self-Care Level 2- Cultivation & Development of Internal Organ Energy Pathways
6/5/2015 » 6/7/2015
CEU: The Best of Master Tung's Magic Points
6/5/2015 » 6/7/2015
CEU: Aromatherapy & Essential Oils - Skin Care & Spa
6/6/2015 » 6/7/2015
CEU: Naturopathic Manipulation Tune-Up - Spine & Upper/Lower Extremities
CEU: Weight, Weight, Don't Weigh Me - How a Social Neuroscientist Takes an Easy-to-Understand, Evide
6/12/2015 » 6/14/2015
CEU: CranioSacral Therapy - Level 3 - The Somato-Emotional Release


text:
Rita Maria Schleck
Rita Maria was born in Milwaukee, Wisconsin and is currently living with her husband in Oak Creek, Wisconsin. She received a BFA in illustration from the Milwaukee Institute of Art and Design in 1999. After an 11-year detour of working in the field of cosmetology, Rita Maria has gone back to her true love of painting and devotes herself full-time as an artist.
In her mixed media paintings you will see what inspires her most: truth, emotion, openness and sentiment. Rita Maria loves connecting with the human heart through her artwork and dreams of inspiring others to open up to their own truths.
These days you can find her working in her studio in Jefferson.
View This Artist's Artwork


text:
Real Madrid star Cristiano Ronaldo says he enjoys playing for coach Carlo Ancelotti.
Ronaldo was speaking with France Football.
"The team has a lot of confidence in itself this year. On the pitch there aren't many differences between last year's team because Ancelotti has done a good job. He's a good person, a great coach, he talks to me a lot and I'm thrilled to work with him. I feel really good with Real Madrid and, frankly, anything is possible this season.
"I believe that I'll be the best on the pitch if I work hard and have more ambition. Throughout my career I've always considered myself a professional. I've learned a lot from other players like Raúl, Michel Salgado, Gary Neville, Ryan Giggs, Figo, Rui Costa…"
For breaking stories and all the great banter like us on Facebook: facebook.com/tribalfootball


text: PROFIT-SEEKING CACAO FARMERS THREATEN WILDLIFE IN IVORY COAST Written by Jennifer Bihm (Contributing Writer) 09 April 2015 Profits from cacao farming have been so generous that farmers invaded national parks in order to carve out plantations, cutting down forests and turning animal habitats into inhospitable treeless ... read more >> AMATEUR PILOTS FILL THE SKIES IN GHANAIAN PARAGLIDING FEST Written by Global Information Network 09 April 2015 From Good Friday to Easter Monday, an annual ritual takes place in Ghana quite unlike the egg rolling contests found in the U.S. People from around the world come to launch themselves into the air ... read more >> KENYAN TROOPS DELAYED RESCUE FOR CLOSE TO 15 HOURS, SURVIVORS SAY Written by Global Information Network 09 April 2015 Frightened students at Garissa University in northeast Kenya, hid for what seemed like a lifetime as a small band of al Shabaab terrorists lined young people up on the floor and put a bullet in the ... read more >> Kenya Attack Survivor Found Hiding In Closet Two Days After College Massacre Written by CHRISTOPHER TORCHIA and TOM ODULA Associated Press 09 April 2015 Cynthia Cheroitich, 19, a survivor of the attack on Garissa University College who was found on Saturday, two days after the attack. Photograph: Andrew Njuguna/AP Somalia's Islamic extremist group al-Shabab ... read more >> Councilman Price Issues $50,000 Reward in Hit and Run of 86 year old woman Written by Sentinel News Service 09 April 2015 Victim still in serious conditions after suffering multiple broken bones and fractures being struck near USC on March 16 Councilman Curren D. Price Jr. announced Thursday April 2 his introduction ... read more >> Jada Paul Hosts 4th Annual Prom Dress Giveaway Written by Sentinel News Service 09 April 2015 Jada Paul (at right in both photos) displays two of the many prom dresses high school girls could obtain for free. Jada Paul, wife of 8-time NBA All Star, Chris Paul, recently hosted her fourth ... read more >> This Week in Black History (April 9-15) Written by Amen Oyiboke, Staff Writer 09 April 2015 (Sidney Poitier) April 9 1950- Actress Juanita Hall became the first African American to win a Tony Award for best-featured actress in a musical for her role as Bloody Mary in, "South Pacific." April ... read more >> Black Press Faces Challenging, but Hopeful Future Written by Freddie Allen Senior Washington Correspondent 09 April 2015 NNPA President and CEO Benjamin F. Chavis discusses the "State of the Black Press" (NNPA Photo by Freddie Allen) WASHINGTON (NNPA) – Jordan Shanks, a sophomore English major at Howard University ... read more >> Detroit-area woman, 115, now listed as world's oldest person Written by By Associated Press 09 April 2015 115 year-old Jeralean Talley of Inkster, Michigan is now reportedly the world's oldest person, following the six day reign of Gertrude Weaver who has died in Camden, Arkansas. Rob Muir reports. (courtesy ... read more >> Dr. Maya Angelou Forever Remembered with Postal Stamp Written by Kenneth D. Miller, Assistant Managing Editor 09 April 2015 (courtesy photo) A spirited pledge of allegiance presented by the Crenshaw High School girls color guard, a soulful rendition of The Black National Anthem by singer/actor Terron Brooks and fitting ... read more >> Another Senseless Killing Shakes Southland Written by Kenneth D. Miller, Assistant Managing Editor 09 April 2015 Hawthorne Mother Murdered in Front of Son (courtesy photo) This should be a week when MTA bus driver and mother of a 12-year old son, 44-year old Denise Chiffon Berry is finishing up another bus ... read more >> Metro Pilot Program to Provide Support to Small Businesses Impacted by Rail Construction Written by Sentinel News Service 09 April 2015 Los Angeles Mayor and Metro Board Chair Eric Garcetti, along with Metro Board members Los Angeles County Supervisor Mark Ridley-Thomas and Jacquelyn Dupont-Walker, delivered checks totaling $66,310 to ... read more >> Jailed Atlanta Educators Await Fate in Cheating Scandal Written by Special to the NNPA from The Washington Informer 08 April 2015 A group of former educators in Atlanta convicted in a widespread test cheating scandal now await their fates behind bars. Eleven defendants were convicted of racketeering and other charges April 1 in ... read more >> Supporters of Mumia Abu-Jamal Worried About His Health Written by Special to the NNPA from The Final Call 08 April 2015 At Final Call presstime supporters of Mumia Abu-Jamal said the 60 year old had been hospitalized March 30 for a medical emergency. According to reports Mr. Abu-Jamal was rushed from the State Correctional ... read more >> Black Fraternity, Police Officer Face Million-Dollar Lawsuit Written by Khari Arnold, Special to NNPA from Howard University News Service 08 April 2015 WASHINGTON – Kappa Alpha Psi, one of the nation's largest and most prestigious black fraternities is facing multi-million dollar lawsuits for hazing, the latest by a 45-year-old Washington man who ... read more >> Supporters of Man Who Filmed Death of Eric Garner by Cops Fears for His Life Written by Brian E. Muhammad,Special to the NNPA from The Final Call 08 April 2015 Eric Garner and his wife Esaw Garner Activists' question why Eric Garner, a husband and grandfather, is murdered by New York police in broad daylight on video tape and the only person incarcerated ... read more >> California moves to kill the lawn, save the water Written by ELLEN KNICKMEYER AND GILLIAN FLACCUS, Associated Press 03 April 2015 A home with a swimming pool sits near hillside, Thursday April 2, 2015, in Altadena, Calif. California Gov Jerry Brown on Wednesday, April 1, ordered a mandatory 25 percent overall cutback in water ... read more >> Woman Victim and Slain Shooter Identified in Hawthorne Murder Written by City News Service 03 April 2015 A woman who was fatally shot in her car after her 12-year-old son made eye contact with a passenger in another vehicle has been identified, while authorities announced the arrests of two associates ... read more >> YMCA of Metro L.A. Partners with Mayor's Office for New Programs for At-Risk Youth Written by Danielle Cralle, contributing writer 02 April 2015 YMCA CEO Alan Hostrup address the crowd at city hall on March 25. On Wednesday, March 25, the mayor's office announced its partnership with the YMCA of Metropolitan Los Angeles' new cradle to career ... read more >> Hezekiah Walker Honored with NNPA Torch Award Written by Elaina Johnson Howard University News Service 02 April 2015 (Hezekiah Walker) WASHINGTON (NNPA) – Grammy Award-winning artist Bishop Hezekiah Walker can add the 2015 Torch Award for religion to his list of accomplishments as a gospel music artist and ... read more >> Rethinking the Recognition of Doris Miller Written by Marsha Rose Joyner Special to the NNPA from the Afro-American Newspaper 02 April 2015 (Courtesy photo) First in a series. Doris "Dorie" Miller, and hundreds of other messmen who were serving breakfast that morning, never dreamed that day in 1941, was the time for them to be heroes. ... read more >> Broader Hiring Practices for Ex-Offenders Receive Bipartisan Support Wade Henderson deplores "overcriminalization" of Blacks. Written by Freddie Allen Senior Washington Correspondent 02 April 2015 Wade Henderson deplores "overcriminalization" of Blacks. WASHINGTON (NNPA) – As the economy recovers and violent crime hits 30-year lows, lawmakers continue to trade in their tough ... read more >> Banking Exec Earned his Money Written by Jordan Shanks NNPA Intern 02 April 2015 Doyle Mitchell received NNPA Torch Award for Business (Photo by Worsom Robinson) WASHINGTON (NNPA) – For many professionals, the road to success starts with humble beginnings. Because B. Doyle ... read more >> Jackie Hampton Left Corporate America for Black Press Written by Beunkka Davis and Anissa Pierre NNPA Interns 02 April 2015 Jackie Hampton at Black Press Week (Photo by Worsom Robinson) WASHINGTON – Many African Americans begin their career at Black businesses and move own to better-paying jobs in Corporate America. ... read more >> Mike Gipson Being Sued Written by City News Service 02 April 2015 Former Carson City Councilman Mike Gipson is being sued by the man he defeated in a heated race for the 64th Assembly District in November over a campaign ad that allegedly made his opponent look like ... read more >> Page 10 of 199 StartPrev567891011121314NextEnd Subcategories Breaking News Campaign Watch Celebration of Life Exclusive International Legends Local National Politics Press Releases


text:
400 dead, P4B in property, crops destroyed by 'Pablo' –NDRRMC
More News from Frances Mangosing
More News from INQUIRER.net
MANILA, Philippines — The number of deaths in the wake of typhoon "Pablo" (international codename: Bopha) has risen to over 400 with damage to property and crops estimated at P4 billion, the National Disaster Risk Reduction and Management Council said Friday.
As of 6 a.m., there were 418 dead, with only 73 identified.
Most of the fatalities were from the hardest-hit areas of Davao Oriental and Compostela Valley, as caused by floods and mudslides.
Damages to properties and agriculture have gone to over P4 billion, the NDRRMC said.
Injured persons were at 445, while 383 remained missing.
There were over 5 million affected persons in Mimaropa, Eastern Visayas, Central Visayas, Western Visayas, Northern Mindanao, Davao region and Caraga, with over 300,000 still in evacuation centers.
Pablo also destroyed at least 10,000 homes, the NDRRMC report said.
Four provinces and 26 municipalities were declared under a state of calamity in Mimaropa, Central Visayas, Northern Mindanao, Davao region and Caraga.
Pablo, weakened into a tropical storm, is slowly heading out of the country and was last seen 530 kilometers west of Calapan, Oriental Mindoro at 4.am. It packed maximum sustained winds of 110 kilometers per hour and gusts of up to 140 kph.
Get Inquirer updates while on the go, add us on these apps:
Disclaimer: The comments uploaded on this site do not necessarily represent or reflect the views of management and owner of INQUIRER.net. We reserve the right to exclude comments that we deem to be inconsistent with our editorial standards.
To subscribe to the Philippine Daily Inquirer newspaper in the Philippines, call +63 2 896-6000 for Metro Manila and Metro Cebu or email your subscription request here.
Factual errors? Contact the Philippine Daily Inquirer's day desk. Believe this article violates journalistic ethics? Contact the Inquirer's Reader's Advocate. Or write The Readers' Advocate:
c/o Philippine Daily Inquirer Chino Roces Avenue corner Yague and Mascardo Streets, Makati City,Metro Manila, Philippines Or fax nos. +63 2 8974793 to 94


text:
Hi Everyone, I have an Autocord that seems to have a focus issue.
The focus at infinity is good - the taking lens matches the viewing lens, I assume because everything is sharp on the negative even wide open.
I have never noticed a focus problem, and I routinely look very close at every negative. I usually stop down though, and focus about 7 or 8 feet out to infinity though.
When I notice a problem is wide open at near the close focus limit. Every photo taken this way seems to be focused 3 or 4 inches behind where I focused...and it is consistent on every frame of 2 rolls so I think I can rule out user error.
So my question - could the taking lens and viewing lens be out of sync?


text:
TTBN Alpha
- Login or register to post comments
- by TinHead
- Collected by 19 users
Update - 10.02.2015 - Nothing more to add
Marking this thing as done as I'm definetely not going to continue work on this.
Everything related to this one is hosted on Github links below.
LINKS to gihub:
Code https://github.com/TinHead/TTBN-Alpha
Designs: https://github.com/TinHead/3d-designs
Update - 20.05.2014: SD Card Image
Note: This image is configured with the bare minimum and for specific hardware
I'm using an UVC compatible webcam (logitech C110) and an Edimax wifi dongle based on RTL8188CUS chipset supported by the rtl8192cu kernel driver. Unless meeting the specs NOTHING else will work as is!
So here it is the software!
To get it working in your own wifi network you need to:
- download image from above drive
- unzip
- get empty SD card - 2Gb minimum image is 2Gb in size
- flash image to it - now this depends on your OS on linux I do:
dd if=alpha.img of=/dev/xxx
where /dev/xxx is the SD card
- I will not post or support windows ... sorry
- once image is flashed you need to mount the SD card partition 2 and edit /etc/wpa_supplicant.conf to match your network by changing the defined network entry in the file ... SSID and PSK pass. SSID == ypur network name. PASS ... well simplest is to run wpa_password on you favorite Linux distro or use this to get the encripted string http://www.wireshark.org/tools/wpa-psk.html
- once done save unmount the SD ... insert to Pi and boot
- check router for IP assigned
Now if everything goes well you should be able to SSH into it with user root no pass ... if not you need to use the serial console.. sorry :)
You should be able to use Chrome to open http://your_lan_ip:8888 and get to the web interface.
Regarding hardware connections I'm using GPIO's 7,8 for the track servos and 24 for the webcam servo.
Warning! Do Not Attempt To Power Servos From the 5V pin of the PI you will KILL it!
Disclaimer: I do not care if your house burns down, your dog hates you, you cause an earthquake or anything else! This is offered as is. No support is offered ... unless you pay :)
Update - 15.05.2014 - We're Rolling Baby!
Finally working!
|From Share
|From Share
|From Share
Change list:
- created the top side + camera mount
- added a third servo to tilt camera
- changed the web interface to accomodate the web cam tilt
Working! Tested by Frits, Gareth, Bdk, Enigmerald, Badji, Jinx and others (sorry forgot who else :D )
Need to fix some issues with tilt code ... will push latest to github when done.
- fix tilt code
- redo track tensioners (never really happy with them)
- various tweaks to track design
- various tweaks to casing
Update - 16.04.2014 - engines tunning
Finally got new servos namely the TowerPro MG90s ones. Full metall gearing yey!
Modded one last night for continuous rotation keeping the electronics so it can be cotrolled just like regular servos.
To mod this type of servo you would do the following steps (yes I'll do a howto wiht pics) :
1. unscrew the 4 screws
2. remove the output gear (the last one) from the pot shaft
3. use a 1.5 mm drill to drill out the shaft lock hole so the output gear can easyly turn around the shaft
4. cut the plastic tab located underneath the output gear
5. find the center of the pot as precise as possible and glue the shaft in place so it stays centered
6. put the thing back together and enjoy :)
I'll have to update the tensioner design again ... I found I was pushing the track way too much, I'll make it shorter.
Also will work on the cover so it looks nice :)
Update - 4.03.2014 - ain't called alpha for no reason
Found a bug in the track design, you will need 28 links using hard pla :/
Also the tensioner needs to be longer. ... so a bit of redesign is in order.
Later edit: files fixed in git ... printing now.
<--- older stuff below --->
New project in works for a while.
I have designed this one with the following in mind:
- printable by everyone not just me
- off the shelf motors and batteries - easy to source
- rpi + arduino nano + l293 (or what ever else fits) as electronics
- webcam as the main sensor - GroG mentioned rpi cam but I think it's a bit pricey and badly supported
- whatever else comes to mind
I have built a first prototype to test things out and it seems fine, so I think it's ready for some real world testing.
I'm using the RPI because of my own interests but the electronics can be changed to anything really.
The current state of this does not have an upper case part, I did not design it yet but it will be added when I get to.
Here is a (draft) BOM to get things going:
1. Printed parts:
1 x lower_frame.stl
1 x battery_pi_mount.stl
2 x track_spacer.stl
1 x track_panel_right.stl
1 x track_panel_left.stl
4 x tensioner_wheel.stl
2 x tensioner_upper.stl
2 x tensioner_lower.stl
2 x idler_wheel_interiour.stl
2 x idler_wheel_exterior.stl
2 x drive_wheel_interior.stl
2 x drive_wheel_exterior.stl
26 x single_track_link.stl per track so 52 in total
2. Vitamins:
2 x continous rotation 9g microservos
3 x 18650 li-ion batteries - mine are 2000mAh ones
10 x 623zz bearings
2 x 45 mm long 3 mm diameter threaded rod
12 x 10 mm long 3 mm diameter screws (well I hope I counted well)
lots of 3 mm washers and nuts
2 x springs - ~8mm internal diameter , ~9 mm external diameter, ~ 16 mm in length - you'll probably have to experiment here
52 x 1.2 mm diameter, ~ 13 mm pins -- well anything goes here I used some steel wire
3. Electronics
1 x raspberry py
1 x arduino nano + motor driver shield ( this is to be settled but is what I have in mind)
1 x webcam mine is an el cheapo logitech --- to be settled when we do the upper part
1 x 3A Ubec to stepdown to 5v
4. Build instructions:
Print all stuff, I used 0.2 mm.
Assemble as in renders below:
... and top view
I have setup a github repo here for the STL's not sure if it helps anyone to post the blend file:
Have fun!
<--- Older entries below --->
Some pictures from the build below:
|From Share
And one track complete:
|From Share
Current state:
|From Share
Today's update:
|From Share
... backside
|From Share
This is a really neat bot!
Thank you for sharing. This would be a neat platform for experimentation, or playing around, or a great gift to a kid.
Have a great day!
what an update!
ive intended to play with tornado on the Pi.
Been tossing back and forth between that and node.js...
How do find tornado to work with?
PI setup
Hi TinHead
This is absolutely amazing. I have been dabbling with microcontrollers and the Raspberry Pi and have been frequenting this site for months in search of that one project to inspire me to actually build one, and this is most certainly it! I even signed up just so i could post :-)
I am quite comfortable with the Arduino side of the project, however some more info on how the Pi is setup would be wonderful.
I need to find a 3D printer now :-)
Oops - updated my profile :-)
Thank you for taking the time to reply.
I would be very much interested in a set of parts :-)
Ah, I love how it is just running off the Pi, it makes perfect sense!
In the project that is brewing in my head i am going to be potentially using an Arduino to handle some sensors and servos etc.I need to learn to tackle things step by step, however; so setting up the Pi to handle movement via the GPIO pins is a much more sensible option for now :-)
That set up sounds fantastic; I am currently adding an Arduino and motors to a Wall-e toy for control via bluetooth, and one thing i was thinking of was rather than having mutliple apps on multiple devices to control it, why not have one 'built in' and served by the pi on a browser?!
If you could provide me with an image that would be absolutely amazing, and i would forever be in your debt.
I'm inexperienced but can find my way around with Python and Arduino/Processing, however Linux is something i haven't really got to grips with as of yet. I am going to right that wrong as soon as possible though!
Don't worry, i take full responsibility of my actions - I'll build it at work just in case :-D
Thanks again for making such a brilliant project!
Ha ha, I'm not colourist :-)
Any colour would be good for me ha ha!
I've just been given (when i say just, i mean in the last few minutes!) a base from an old toy to play around with, complete with tracks and motors. I have a spare Pi and a few Arduinos so may start playing with that tomorrow on my lunchbreak at work, just to get the the project off the ground and mount it into your lovely enclosure at a later date :-)
I appreciate the help buddy, thankyou very much!


text:
What's new? Check out today's PDN Page 1. (And activate your 'all access' digital pass)
PDN's front page for today's Clallam County readers.
Print This | Email This
Most Popular this week
2nd UPDATE — Fugitive captured on Port Angeles' west side after many Clallam residents issued electronic lock-up warning
Fugitive captured on Port Angeles' west side after many residents issued confusing 'stay inside with doors locked' warning
6th UPDATE — Port Angeles smashes Bar Harbor, Maine — and now faces Chattanooga, Tenn. in championship for 'Best Town Ever' of 2015
WHEN YOU GET home delivery of the Peninsula Daily News, the digital comes free.
Subscribers to the print PDN (Sunday through Friday or Friday/Sunday only) enjoy free "all-digital access" (an $8.95-per-month value) including:
■ eEdition — our electronic page-by-page replica of the print edition. Now you can read the PDN anywhere — on the deck of a boat in Port Townsend, or in Rome.
■ Unlimited access to www.peninsuladalynews.com, the dominant news, information and advertising website on the North Olympic Peninsula.
Track breaking news via the website through the day — and use our electronic archives for stories you might have missed or want to read again.
■ Smartphone/iPad and tablet access.
Instead of paying a separate fee of $8.95 a month, it's all free . . . included with your daily or weekend-only print subscription.
Already a home-delivery subscriber? To get full, unlimited electronic access, visit www.peninsuladailynews.com and click on the link that says "Already a print subscriber? Activate your digital account."
Don't have home delivery? To sign up, phone our circulation department at 360-452-4507 or 800-826-7714. Or click on http://www.peninsuladailynews.com/section/pdnsubscribe
■ The print edition has up to 40 percent more stories and photos than our website.
■ And there are two editions (print AND eEdition) — one tailored to Jefferson County readers, the other for Clallam County readers.
■ ALSO — read faster, absorb more — studies also show you read up to 30 percent faster on paper . . . while retaining more information.
Questions? Please phone publisher John Brewer — his direct number (with voice mail 24/7) is 360-417-3500.
Or email him at email@example.com
Many thanks.
Last modified: June 05. 2014 7:18PM


text:
Adm. Scott H. Swift returned to his home state and relieved Adm. Harry B. Harris Jr. as commander of the U.S. Pacific Fleet during a change of command ceremony on Joint Base Pearl Harbor-Hickam,
The German Defense Minister Ursula von der Leyen is visiting India lobbying for the purchase of German Stealth Submarines and European military hardware, say local media.
Amid increasing Chinese presence in the Indian Ocean region, Navy Chief Admiral R.K. Dhowan said that Indian Navy "minutely" monitors the activities of its Chinese counterpart in the region,
Around 300 "boat people" have landed on Thailand's shores in recent weeks, Sek Wannamethee, director-general of the information department at Thailand's Foreign Ministry, said on Friday.
The United States said on Friday that China had placed mobile artillery weapons systems on a reclaimed island in the disputed South China Sea, a development that Republican Sen.
Unified Command responding to cleanup aboard vessel in Seldovia, Alaska
A Unified Command consisting of representatives from the U.S. Coast Guard, U.S. Department of the Interior,


text:
Demeter creates the Mighty Minnie pedal board amp
By Paul Ridden
October 4, 2013
There are times when packing a full rig for a small venue tour is just not practical and sacrifices have to be made. When the topic of being forced to use awful-sounding back line amp rentals came up in a conversation between slide guitar master Sonny Landreth and veteran amp maker James Demeter, an idea for an amp small enough to mount on a pedal board began to take shape in the latter's mind. The Mighty Minnie hybrid single channel guitar amp that resulted is now being made available through Demeter's Custom Shop.
"The pedal board amp started as a concept from our chief tech Rick Mulikin to make a small monitor amp and speakers for a pedal board," James Demeter, the principal designer and owner of Demeter Amps, tells Gizmag. "We had been working with next generation Class-D power amplifiers for our bass pre-amps and realized that we could easily fit a 100-watt amp in a small chassis with a hand-wired, point-to-point, all-tube TGA-3 clean channel pre-amp. We had been very successful in warming up the sound and keeping all the tube tone in our Bass Amplifiers with our exclusive tube circuit driving a special Jensen audio transformer to run an 800 watt Class-D amplifier. We incorporated that technology in the pedal board amp."
The Mighty Minnie (TGA-1-180D) features the same hand-wired, clean channel Demeter tube pre-amp as the TGA-3, a Jensen audio transformer, and an audiophile-grade Class-D power amplifier. Sat in front of the caged tubes are chrome-topped knobs for gain control, bass, mid and treble tweaking, and a master volume dial that has a pull pot to give an extra 20 dB of range. There's a standby stomp switch, and a status light shows whether Minnie is active or not.
A regulated 9 V output port at the front can be used to power any neighboring pedals on the board, with the signal routed through the amp via a 0.25-in instrument jack. The Mighty Minnie is connected to speakers courtesy of two 0.25-in audio-out jacks to the back, which is also where you'll find the amp's power input and on/off switch. The 10 x 7 x 4.25 in (25.4 x 17.8 x 10.8 cm), 4.5 lb (2 kg) unit is reported capable of throwing out 60 W into 16 ohms, 100 W into 8 ohms or an incredible 180 W into 4 ohms.
"We set up the pre-amp so it can be run clean or can give you an old school Edge/Overdrive," explains Demeter. "The idea of the amp is to keep the sound clean and get most of your distortion using your pedals. I must say with a Humbucker or a single coil with a bit of boost that you could get a very good over drive tube amp sound."
Originally designed and built as a one-off for Sonny Landreth, Demeter decided to make more after a jazz guitarist friend, who was called in to help fine-tune the tone, asked to buy one, and then sold two more to his friend.
"We decided maybe this fills a niche that we did not anticipate," says Demeter. "So we decided to make more. We can customize a bit. We can put in line level inputs so the player can use a bass pre-amp with it or run his stereo through it, for example. We can tune the EQ bit and lower the front end gain for more head room for jazz players. We can also put in International power switches."
The Mighty Minnie is hand-built in Templeton, California and carries a list price of US$1,199, but is currently available direct from Demeter Amps for $899.
Product page: Demeter Amps
Amps with a thermionic valve pre-amp and solid state output amp are the bastard children of the amplifier world which nobody really likes. What would you power with this? A single speaker cabinet or stage speaker? Sacrilege... Rather stick with a real all valve combo amp if you really must save space. Or avoid tiny clubs altogether and break out the all valve half stack or even full stack:-)Leon Van Rensburg
Rock stars can just hire an extra roadie to cart all their tube gear. As for me (engineer, amateur musician), all solid state is the way to go. And I've spent much of my career designing tube equipment (for microwave radars, though).Captain Obvious
I'm an engineer/musician too. I would have thought that if you're going Class D (constructing the waveform with pulses then smoothing them out) then any audio quality advantage you get from using tubes would be swallowed up in the distortion Class D inherently produces. I'm with Captain Obvious, all solid state is the way to go. You can imitate any other kind of amplifier with solid state including tube distortion.warren52nz


text:
Tiny chihuahua poodle puppies ready to view
We have 5 gorgeous babies ready for their new homes shortly. Beautiful chihuahua poodle puppies . Viewings available from now. Both mum and dad can be seen as are our own family pets. Dad is champion pedigree KC Reg Tri colour chihuahua Mum is KC
- DOB:23 Apr 2015
- Rehome date:18 Jun 2015


text:
"Coach Mattison told me what the Ravens were about, what he thought," Beyer said. "He definitely encouraged me. I hold his opinion in high regard."
neutral site games
Unverified Voracity Has Words For One Word
Scrimmage video. Fan-based, so wobbly.
Perverse incentives create perverse results. It is of course completely nuts for Michigan to play Florida in Dallas. The stadium is smaller, the fanbases are far away, and the pageantry of college football is largely replaced with sterile NFL lawyer spaceship accoutrements. But people do it because they get the money.
After Wisconsin scheduled LSU in a goofy neutral-and-neutral situation, Jim Delany issued a memo that the Cedar Times Gazette has unearthed:
Delany's letter, which was obtained by The Gazette, highlighted the league's support for neutral sites provided at least half of the series occur within the Big Ten footprint and under the league's television agreements. Delany wrote an arrangement would be "disapproved" if a Big Ten game was not designated as the home squad in at least half the games or if it was a one-game event that took place outside the league's television umbrella. …
"We applaud and very much appreciate your efforts in doing so, as this should create value for your teams and fans as well as for our television partners and, therefore, for all Conference members. But please keep in mind the above policies that are important to all of us as we share collectively in the revenue generated by our televised games."
I'm not sure what "disapproved" means here. Could be "we will not let you do this"; could be "we will raise our mighty eyebrow at you but take no other action."
In any case the memo indirectly indicates why neutral site games are popular: the two teams participating can split the TV money between themselves instead of between themselves and Indiana and Purdue and a bunch of other teams that are not in fact playing. When there's a Jerryworld game, ESPN and Jerryworld get the rights and then give home-team-sized slices to both participants. The Big Ten doesn't like that.
The Big Ten can pound sand. Scheduling real games would be so much easier if the teams in them actually saw the benefits without having to leave campus. There is zero reason that a Michigan-Florida home and home should be less lucrative than a neutral site game for the people involved.
Thankfully it sounds like Michigan's trip to Jerryworld in 2017 will be their last, by league decree. It's for the wrong reason, but these days that's all you can hope for.
Hatch things. Good Morning America had him on:
I am going to judge you on your word. Big Ten coaches given one word to describe their teams!
Illinois' Tim Beckman: Family
"Can you help me find them? I'm not supposed to be out after 7 PM."
Indiana's Kevin Wilson: Cusp
That's not an adjective. The Hoosiers are not seeming particularly cusp this morn.
Iowa's Kirk Ferentz: Developmental
Neither is this unless it's followed by "-ly disabled," but I like that Ferentz managed to be even more boring than boring. He's probably in a band called White Toast and that's one of their songs.
Maryland's Randy Edsall: Hungry
Boring, and not in a fun Ferentz way. Boring in a boring way. Randy Edsall is in a band and their one song is "this is not a band it is just a boring man telling you to eat your vegetables."
Michigan's Brady Hoke: Together
…now that our first round left tackle is gone
Michigan State's Mark Dantonio: Committed
…pass interference and still weren't found out
Minnesota's Jerry Kill: Hungry
This would be boring except for this video of Jerry Kill eating a tiny burrito:
Nebraska's Bo Pelini: Exciting
Accurate. Nebraska is not great but they are a cat explosion waiting to happen.
Northwestern's Pat Fitzgerald: Focused
…until the fourth quarter.
Ohio State's Urban Meyer: Fast
Accurate, in fact tells you something about desired composition of team, relatively un-boring.
Penn State's James Franklin: Perseverance
Again with the non-adjectives.
Purdue's Darrell Hazell: Hungry
Would be boring but in this case I think Darrell Hazell may be saying that his players are literally hungry because they can't figure out which hole to put the food in. "NOT THAT ONE," Darrell Hazell screams for the third time today, "THAT ONE ISN'T EVEN A PART OF YOUR BODY."
Rutgers' Kyle Flood: Hungry
wait why is this guy even listed
Wisconsin's Gary Andersen: Youthful
Well… yeah. Joe Namath ain't walking through that door.
Meanwhile, Spurrier said "decent" because hail Spurrier. Mark Richt said "wow" for some reason. I ain't saying that Dave Brandon goes around wearing Mark Richt's skin. But I ain't saying otherwise, neither.
Would you say that your decisions are film and evidence-based? Hoke:
"The evidence for making decisions is on the film," Hoke said Saturday night after the team's public scrimmage. "It's evidence-based. Based on film."
No word on the moisture status of his upper lip.
Another "students are gone" article. This one from USA Today is standard-issue. It never ceases to amaze that athletic directors can say this…
"I don't think it's a targeted demographic problem; I think it's more of a (high-definition) TV, living room, leather couch problem and we have to give the people a reason to come to our live product," Washington athletics director Scott Woodward said. "It is something we're going to have to address and deal with."
…and then marvel at the fact that it's tough to sell tickets that have spiraled upward relative to inflation, nearly tripling since 2000. Surely there is an athletic director out there who can figure out why they might be having attendance problems. Take 2, and then take this other 2, and somehow we have to reach 4.
The article has another pile of lukewarm solutions that aren't going to fix much of anything. One thing that could help: stop treating students like enemies. Michigan gets the vapors when a student says the word "sucks" and tries to drown it out; the ushers in the student section are constantly harassing anyone who does anything that looks even slightly like liability. You've got a choice here: loosen things up and accept the fact that you're going to have slightly higher insurance premiums, or continue to turn off your future customers with adversarial relationships between students and your main point of contact with them.
[Via Get The Picture.]
Italy stuff. The entire first game is available on the tubes. UMHoops has highlights of game #3.
Etc.: MSU WR MacGarrett Kings doesn't even get standard-issue one game DUI suspension. Notre Dame previewed by Paul Myerberg. An overview of where the various NCAA lawsuits stand. The Kessler suit is The Big One. I'm in a sidebar of this ESPN story on the state of Michigan. NOPE.
MVictors interviews Dan Dierdorf. Genuinely Sarcastic comes back for a post about Michigan football that naturally includes a section on Stalingrad. Notre Dame scandal is always a good opportunity to rip Notre Dame.
Unverified Voracity Finds Worst Headline
Not the Onion. News headline:
MSU challenges officials to take control of game vs. Michigan
Are you man enough to call another 100 yards in personal fouls on Michigan State, refs?
Also, Tyler Hoover is supposed to return to the lineup at DT. Not sure how much impact that will have.
Also not the Onion. This is where the rivalry is at the moment:
Michigan prepping for a 'figurative fist fight' in physical tilt vs. Michigan State
More like LITERAL KNIFE FIGHT AMIRITE.
Also also not the Onion. We have a formidable secondary?
Michigan's formidable secondary 'looking to get after it' against MSU
I'm going to go away and hope this is true forever.
YOU DON'T KNOW HOW THINGS ARE CAUSED. Winner?
Former Michigan star Mike Hart's infamous comment sparked Michigan State's resurgence in series
Worst article is easy. Matt Charboneau's flufftastic puff piece on Gholston, which does the same thing all attempts to defend Gholston do: focus on the meaningless punch that brought a suspension while ignoring the Denard helmet twist and the Lewan arm bar. No one cares about hitting a guy in a helmet with your fist in the heat of whatever. It's unfortunate that the Big Ten focused on that instead of the truly dirty stuff.
He's just misunderstood, you see, and he has kid, so he must be an awesome dude. They don't just hand out kids to anyone. You have to be licensed.
Maybe he just went crazy that one time but if you're going to write an article about it at least have the honesty to detail the things that happened.
Uniformz? A photo of a chrome-tastic MSU helmet is floating around the internets and the rumor is they will be deployed Saturday:
Hopefully Michigan doesn't respond in kind as they did last year, if this is actually a thing that is being worn. I worry that someone somewhere is saying "we have to bridge the chrome gap!" and not being shot.
MSU scouting bits. Highly recommended are Ross Fulton's breakdowns of what Ohio State did against MSU. The MSU defense:
As expected, Michigan State adopted an aggressive style that focused upon attacking Ohio State's inside zone read. Michigan State generally operated from their 40 over defense with their Will linebacker walked over the slot receiver.
The Spartan Will linebacker's role was not to cover the slot receiver, however. Instead, he was tasked with accounting for Braxton Miller on the zone read, allowing the defensive end to crash the zone play. In essence, the Spartans ran a constant scrape exchange.
In response, OSU shot their H-back outside the defensive end and hit the edge or used him to block the crashing DE and read the slot-oriented LB, or they used outside runs that used the aggression of that DE to open up the corner. Expect Michigan's inside zone to be a maintenance play that picks up a few yards, allowing other runs to bust for larger gains.
Tremendous also has a breakdown, one that focuses on the defensive tackles—who are not good, thus the Kittredge switch this week. Included are many amazing displays of Spartan DTs put on skates by the OSU OL. I'm with Mr. Larson: block Gholston, option someone else, screw rollouts, especially naked ones.
Fulton's item on the MSU offense vs the OSU defense is a little less relevant because Michigan is mostly a one-high cover three defense and OSU is transitioning to cover four. Hankins did clobberate the MSU run game as a three tech—Will Campbell pad level versus bad guard play come on down?
BONUS: Fulton breaks down what the hell happened to OSU's defense against Indiana.
OH BOY. Hopefully this is Brandon not ruling out anything when someone brings up the idea of a neutral site game in a Q&A and not actually wanting to continue college football's worst trend:
But he did say Wednesday that he remains open to all possibilities for the newly-created void on the Wolverines' schedule beginning in 2015.
Whether it's a home-and-home with a big-name opponent, or another possible neutral site game, similar to this year's Cowboys Classic against Alabama in Arlington, Texas.
"We're looking at both," Brandon said. "The key thing for us is to try and make sure we're playing in a venue that gives our fans access, and economically, provides us the best opportunity that justifies going on the road.
"We put 110 or 112,000 people every game in our venue, it's hard to go play in front of 35,000 people."
Ugh, ugh, ugh. A neutral site game gives fans less access than a home and home because it's a game in the middle of nowhere in a smaller stadium. No more neutral site games—we renovated the stadium for a reason, I assume, and not "so Slippery Rock can play there."
This isn't that hard: see MSU and OSU, currently loading up with quality nonconference home and homes not against opponents with 35k seat stadiums… because those don't exist in BCS conferences. Brandon must wake up at night tossing and turning at the agony of having to go to UConn next year. We get it. We also don't care. No more neutral sites.
Oh, man. Don't listen to them, Dylan Larkin.
While perusing my Twitter feed, I came across this tweet from U.S. NTDP Under-18 Team goalie Thatcher Demko and reply by Michigan commit Evan Allen:
"@thatcher_hockey: Larkin is Screetch" hahahha omg he IS screetch
via Michigan Hockey Net
Kids in high school still know who Screech is?
Mac Bennett stepping up. If Michigan can ever ice their full-strength defensive corps it will be a thing to behold($):
"Our guys liked his poise out there, his ability to handle and move the puck," said Trevor Timmins, Montreal's Director of Amateur Scouting. "He's a gifted skater. That's the one thing that he can rely on to get him to the NHL. He's not a big guy so he's had to add some size and strength, but he's in a great situation at Michigan, with some outstanding coaching, and we're seeing that development there.
"Similarly to Greg Pateryn last season, this season Mac is being leaned on to log a lot of ice time, and to play in all situations - be a leader on the team - and that provides Mac with greater confidence in his ability."
That's still some time away, unfortunately. Here's a Bentley preview from Michigan Hockey Net.
Wojo zings. Wojo zings:
This annual clash has turned into a nasty affair, which can happen when brothers scrap and egos fray. It wouldn't be this way if the Spartans had quietly gone about their business, winning two or three times a decade. But then Mark Dantonio showed up with his deep playbook of scowls, much deeper than his offense's playbook, and started ticking people off.
The Wolverines don't appreciate the Spartans' audacity to physically manhandle them. And the Spartans don't appreciate the Wolverines' continuing attempt to pretend their Ohio-based rival is more important.
Common Michigan State plea: "Heeyyyy, we're right heeeeere! Try to beat us! At least look at us!"
Etc.: Dave Brandon turns down no opportunity to crap on the plebes. Stubhub season ticket quest takes a hit on the MSU game. The Daily on Willis Ward.
Penn State's "fourth down bravery" may have something to do with the fact they have the worst punting and kicking in the country. The Bylaw Blog advocates athletics majors. The new NHL CBA might be better for college programs than the old one. Still waiting on the massive imbalance in AHL eligibility to get sorted out. Genuinely Sarcastic back from the grave. DIAMOND STONE is visiting this weekend. He's a five-star 2015 basketball post.


text:
You won't be able to dismiss this by usual means (escape or click button), but you can close it programatically based on user choices or actions.
"The design process was easy, with the review team fixing the issues I had with picture format. Speedy delivery and all receivers are so happy with the cards. Well worth it."
"The cards and envelopes are of excellent quality, we're very happy with the final product! We love that we get the choice to share a number of images on your thank you cards, this was a big plus! Product was reviewed promptly and delivered days before the estimated arrival time. We couldn't be happier, thank you WPD!"
"Our thank you cards came out great! The picture quality (which I am always worried about when purchasing online) looked fantastic! We even had a problem with our delivery and Wedding Paper Divas was more than happy to resend them without a problem! I love our cards!"
"The bride to be selected a classic, long, white menu to place in the napkins. Navy printing. Wonderful black and white engagement photo on the back. The quality is superb. The text and images are exquisite. As the mother of the groom, I appreciated the customer service. The text would not fit online, but I made a note about what I needed the menu to say and the designers had a proof ready in a day. I used live chat when I had questions. Fast, courteous service, helpful editing. Very accessible. I ordered 10 to test the product and then 220 when the bride to be LOVED them. Highly recommend."
"The quality of the paper was amazing and we got so many compliments on and and people asking where we got them! Common complaint about the top pictures cutting off some of our heads but a designer reviewed and fixed t for us before the final product was shipped !"


text:
Book your room at Hilton Garden Inn Cincinnati-Mason
Please enter your travel dates.
Suburban hotel with restaurant and indoor pool
Situated in the suburbs, this hotel is within 6 mi (10 km) of Loveland Castle, Wall2Wall Soccer, and The Golf Center. Courts4Sports and Alverta Green Museum are also within 6 mi (10 km).
Hotel Features
Along with a restaurant, this smoke-free hotel has an indoor pool and a fitness center. WiFi in public areas is free. Other amenities include a bar/lounge, a business center, and meeting rooms.
Room Amenities
All 110 rooms offer conveniences like refrigerators and microwaves, along with free WiFi, free wired Internet, and MP3 docks. Guests will also find flat-screen TVs, room service, and premium bedding.Information missing or incorrect? Tell us!
Hotel Amenities
Hotel Amenities
Hilton Garden Inn Cincinnati-Mason features an indoor pool and a fitness center. The hotel offers a restaurant. A bar/lounge is on site where guests can unwind with a drink. A computer station is located on site and high-speed wired and wireless Internet access is complimentary.
This 3-star property offers access to a business center and meeting rooms. Event facilities measure 2250 square feet (209 square meters). This business-friendly hotel also offers laundry facilities, dry cleaning/laundry services, and a grocery/convenience store.
Hilton Garden Inn Cincinnati-Mason is a smoke-free property.
- Number of floors - 4
- Business center
- Express check-out
- Fitness facilities
- Free wired high-speed Internet
- Total number of rooms - 110
- ATM/banking
- Safe-deposit box at front desk
- Conference space size (meters) - 209
- Smoke-free property
- Indoor pool
- Bar/lounge
- Breakfast available (surcharge)
- Dry cleaning/laundry service
- Elevator/lift
- Grocery/convenience store
- Free WiFi
- Computer station
- Laundry facilities
- Meeting rooms
- Luggage storage
- Restaurant
- Year Built 2010
- Conference space size (feet) - 2250
- Number of buildings/towers - 1
- Wedding services
Family Friendly Amenities
- Indoor pool
- Free Wi-Fi
- Rollaway/extra beds available
- Grocery/convenience store
- Laundry facilities
- Refrigerator
- Microwave
Available in all rooms: Free WiFi , Free wired high-speed Internet
Available in some public areas: Free WiFi , Free wired high-speed Internet
Room Amenities
- Phone
- Microwave
- Iron/ironing board
- Rollaway/extra beds available
- Premium bedding
- Hypo-allergenic bedding available
- Climate control
- Air conditioning
- Refrigerator
- Coffee/tea maker
- Free toiletries
- Hair dryer
- Shower/tub combination
- Desk
- Cribs/infant beds available
- Flat-panel TV
- Free WiFi
- Free wired high-speed Internet
- MP3 docking station
- Room service
Where to Eat
Cooked-to-order breakfasts are available for a surcharge and are served each morning.
Great American Grill - Onsite restaurant.
Room service is available.
Nearby Activities
Recreational amenities at the hotel include an indoor pool and a fitness center.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Hiking/biking trails nearby
- Golf lessons available nearby
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
- Accessible bathroom
- Accessible path of travel
- Braille or raised signage
- Accessible parking
- In-room accessibility
Hotel Policies
Check-in time starts at 3 PM
Check-out time is 11 AM
Payment types
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.


text:
Seagle Music Colony Musical Revue
- When: Saturday, July 20, 2013, 7:30 p.m.
- Where: Tannery Pond Community Center, North Creek
- Cost: $15
- Age limit: Not available
- Categories: Community, Dance performance, Theater
NORTH CREEK — Our Town Theatre Group proudly announces its annual presentation of the Seagle Music Colony on the Main Stage at the Lyle Dye Auditorium at Tannery Pond Community Center. The performance is part of the Cultural Arts weekend and will take place on Saturday July 20 at 7:30 p.m.
Back by popular demand, this is a revue of the music of one of the most successful Broadway composers ever. It features selections from many of his most popular musicals including Phantom of the Opera, Evita, Jesus Christ Superstar, and Cats. First put together by Seagle Music Colony in 2006, this show is sure to please.
All tickets for the performance are $15. For tickets, please call the OTTG Ticket line at 406-8840 or email your ticket order to email@example.com.
Use the comment form below to begin a discussion about this content.


text:
WILMINGTON, Delaware, September 30 /PRNewswire/ -- According to a new market research report, 'Neurostimulation Market', published by MarketsandMarkets (http://www.marketsandmarkets.com), the global market for neurostimulation products is expected to be worth $3.6 billion in 2009, and expected to reach $10.2 billion by 2014, driven by the multiple treatment applications of neurostimulation products, and the emergence of venture capital in the industry.
Browse 48 market data tables and in-depth TOC on Neurostimulation market.
Early buyers will receive 10% customization of reports. http://www.marketsandmarkets.com/Market-Reports/neurostimulators-advanced-tec hnologies-and-global-market-102.html
(Due to the length of this URL, it may be necessary to copy and paste this hyperlink into your Internet browser's URL address field. Remove the space if one exists.)
The Global Neurostimulation report analyzes the neurostimulation products, applications and technology market over the period 2009-2014. The report studies the major market drivers, restraints, and opportunities for the global neurostimulation market; and also evaluates the major trends in the macro- and micro-markets with respect to different geographic regions.
The steadily rising demand for neurostimulation treatment is mainly driven by the rising incidence of neurological disorders across the globe, the unsatisfactory outcome of existing treatments, and the increasing consumer focus on improving the quality of life and on reducing treatment cost, hospitals stays, and post-treatment side effects.
Neurosurgeons too are seeking more efficient surgical techniques that
involve fewer complexities in the treatment of neurodisorders.
Neurostimulation treatments are rapidly ga
|SOURCE Markets and Markets
Copyright©2009 PR Newswire.
All rights reserved


text:
How fickle the mind of the football fan!
It was not so long ago that Andrey Arshavin was the best thing since sliced bread. He was scoring goals for fun, assisting like no tomorrow and lighting up the red half of North London. On the other hand, Samir Nasri was "good" but not good enough. Played well in the Champions League but didn't look like cutting it in the physical Premier League. Now, it seems, the opposite is true.
While Nasri has been ripping defenses to shreds and is an early contender for the EPL player of the year, Arshavin is baring the brunt of the Emirates' ire.
Fans and critics are commenting on his seemingly lack of desire and effort on the pitch. While his goals and assists are up there with the best, his all round game has been lacking.
However, instead of acting the negative, could it be that the little Russian is just off form? Could he be suffering from an injury that is not bad enough to keep him off the field, but bad enough to affect his performances?
Arshavin isn't the type of player to be involved in everything on the pitch. He is someone that causes surprise, be quiet for 89 minutes but light up the entire stadium with one minute of absolute magic.
There is no doubting that he is a fantastic player, and with Nasri, Cesc Fabregas and Robin van Persie all in form, what harm is it in having Arshavin as an impact player seen as he does not need to be relied upon?
Andrey Arshavin will regain that red hot tempo that saw him become a fan favourite so early in is tenure at the Emirates, as they say, form is temporary, class is permanent.


text:
Smog thick enough to cancel flights hits Beijing
Celebrity real estate developer Pan Shiyi, who has previously pushed for cities to publish more detailed air quality data and who is a delegate to Beijing's legislature, called Tuesday morning for a "Clean Air Act." By late afternoon, his online poll had received more than 29,000 votes, with 99 percent in favor.
On Monday, Wang Anshun was elected Beijing's mayor after telling lawmakers the municipal government should make more efforts to fight air pollution, according to Xinhua.
Last week, he announced plans to remove 180,000 older vehicles from the city's roads and promote government cars and heating systems that use clean energy.
Associated Press writer Christopher Bodeen and researcher Flora Ji contributed to this report.
The Associated Press


text:
GURGAON: In a keenly-fought match, Punjab National Bank (PNB) defeated Namdhari XI through penalty shootout in the 5th Oriental Bank Maharaja Ranjit Singh hockey tournament at the Nehru Stadium here on Tuesday.
PNB and Namdhari XI were tied 2-2 after the regulation time. Yudhveer Singh and Jatinder Saroha scored for PNB while Namdhari's Gurmail Singh struck a brace.
In the penalty shootout, Yudhveer, Navdeep Singh and Jalwinder Singh netted one goal apiece to help PNB win. Gurbhag Singh and Harmit Singh were the scorers for Namdhari XI.
In another match, Punjab and Sind Bank (PSB) rode on Daler Singh's lone goal to beat Army XI 1-0.
More In: SPORT | Today's Paper


text:
By Felix Igbekoyi, Asaba
A GOVERNORSHIP aspirant in Delta State, Ndudi Elumelu, has explained reasons for dedicating his aspiration to God with a warning to his supporters to be careful over arguments on his ambition. He said his reason for dedicating his ambition to God was to seek His divine guidance in the political journey.
Elumelu said this on Monday in Onicha-Uku, Aniocha North Local Government Area, during a sermon for the special dedication service in respect of his gubernatorial aspiration.
He warned his followers, especially the foundation members, to avoid distractions, remain focused and be mindful of their reactions to arguments from members of the public with regards to who becomes the governor of Delta State.
While assuring them that their efforts would not be in vain, as there is already light at the end of the tunnel, he thanked his foundation members for their steadfastness and promised that incentives would be made available for the coordinators to facilitate their task of mobilising the electorate towards the 2015 general elections.
Special prayer was held for the governorship aspirant for divine protection and wisdom in the task ahead. 10 branded buses and 30 tricycles were allocated to the coordinators in the three senatorial districts.
Rev. Fr. Ignatius Chigbo, Assistant Parish Priest, St. Michael's Catholic Church, while delivering a sermon during the special dedication service, commended the wisdom of the governorship aspirant for committing the project into the hand of God, stressing that all successes come from God.