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RR Sport launch: behind the scenes
Daniel Craig takes car reveals to the next level...
Posted: 19 Jun 2013
The Sport's design is a proudly tailored, almost metrosexual affair. Land Rover's urbane design director Gerry McGovern, whom Taylor met for a full briefing, is unusually fashion-conscious for a car designer, and the Sport arguably has as much in common with modern architectural trends as anything else. It also has rather a lot in common with the wildly successful Evoque. McGovern points to a 'faster' windscreen angle, to its more rounded shape with plumper volumes - especially in profile - and a dramatically lower roofline. At a stroke, it makes the outgoing Sport look very old hat. A bit like an old hat, in fact, especially when you see the new Sport on mammoth 22-inch wheels.
"The previous model was a huge success for us," McGovern says, "but it was rather rectilinear and dates from a time when the company was still really establishing itself. The new model has killer proportions, and moves on from the Evoque, which put design at the core of our business. Design is the main differentiator these days."


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Yurbuds Ironman Focus Earbuds
Product Information:
Tired of your earphones falling out? Give the Yurbuds® Ironman Focus Earbuds a chance. Created for the sport athlete, these headphones use a patented Twist Lock Technology that fits perfectly in your ear even when sweating. The earphones are designed to move with the lines of the ear, reducing the pain points that regular earphones can cause.
- TwistLock™ Technology keeps the ear buds comfortably in place with your every move
- FlexSoft™ avoids the nerve rich areas of the ear for a comfortable wear
- FlexSoft™ is made with flexible silicone for a comfortable fit
- Designed to match the contours of your ear for additional wearing comfort
- Sweat proof and water resistant, making them great for use in all conditions
- Rich sound quality with every use
- Developed by athletes for athletes
- Compatible with iPhones, iPods, mp3 players
- Included: Yurbuds Ironman Focus Earbuds, silicone enhancers, 1/8" gold-plated stereo plug
- 14.2mm speaker
- Dynamic driver
- 20Hz-20kHz frequency response
- Neodymium magnet
- Style: V10-11BE-10401
- Yurbuds
Country of Origin: ChinaWeb ID: 11858906

subset: commoncrawl


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St. Francis Brooklyn defeats Sacred Heart 92-80
Updated: March 2, 2013, 8:12 PM ETAssociated Press
NEW YORK -- Ben Mockford scored 22 points and St. Francis Brooklyn defeated Sacred Heart 92-80 Saturday in a showdown for the eighth and final Northeast Conference tournament berth.
Mockford made 6 of 11 from 3-point range as the Terriers (12-17, 8-10) made 12 of 27 (44.4 percent). The Pioneers (9-20, 7-11), who lost their seventh straight, were 4 of 18 (22.2 percent) on 3s.
St. Francis, which will play at Robert Morris in the tournament on Wednesday, used an 18-3 run midway through ...
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The Ethnographic Turn in the visual arts describes a practice in which artists approach other cultures or realities through their research and documentation activities.... more
Much of the work of the Renaissance sculptor Conrat Meit has been lost over the centuries. The Bayerisches Nationalmuseum in Munich has pulled together a goodly collection from around the world which proves Meit to be a master of the pot-bellied feminine ideal of the day. By Birgit Sonna
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Many partners have expressed that they cannot afford to attend WPC due to the cost or the fact that they can't take that much time out of the field. There is good news! A new 2-day pass has been announced. Partners, if you were looking for a cost-effective way to attend WPC, this is your opportunity and this is THE year to attend with all the changes to the partner network! When you register be sure to use the special promotion code in the invite below.
As of last night, June 3rd, NCA partners who are flying out of Minneapolis, can book a ticket for $315 on AirTran. There are also still rooms available ranging anywhere from $179 - $209 and up. However, a lot of the less costly options are quickly disappearing. Basically, here's the breakdown for a partner from Minneapolis to attend WPC for 2 days.
2-Day Pass $ 995
Airfare $ 315
Hotel $ 440 (2 nights @ $220/night)
This is a savings of $1,200 over the cost to attend the entire event!
ACTION REQUESTED – sign up for WPC today then hop on WPC Connect and start entering in your daily schedule; try and connect with as many people as possible during WPC!
As always, let me know if you have any questions regarding this information.
Cheers to a great year!!
Lisa Hughes
North Central Area PTM
You're Personally Invited to WPC
At WPC 2010, you will receive numerous opportunities to network with other partners and Microsoft employees; gain a valuable understanding of Microsoft's new cloud strategy; and learn information about new products and programs that will be announced at the conference.
As a result of partner feedback, we are offering several different options for attendance this year including the, recently announced, 2-Day Pass:
· 2 Day Pass* - $995. Note: This pass can only be used for Wednesday –Thursday only. To take advantage of this special offer, enter PT2DJT6M into the registration code field.
Can you attend the conference for only two days or want to bring additional team members for a shorter time span at the conference? Are you interested in doing a deep dive on driving business with your SMB customers? This is the perfect option for you. Attend Wednesday and Thursday to participate in sessions focused on the SMB space. Additionally, you are invited to join me for the US Central Region Awards & Strategy Session as well as a special Disti TPAM Managed Partner Appreciation Luncheon.
I will be attending WPC and would love the opportunity to meet with you in person and would be happy to facilitate introductions with other Microsoft attendees who you are interested in meeting with. I'm looking for your commitment to attend this year's conference. I'm asking that you please let me know as soon as possible whether you or another member of your team plan to attend.
Below I have highlighted some of the available sessions for taking advantage of the 2-Day pass option*. This is, by far, the best deal if you are wanting to attend and may not have the availability or resources to attend for the whole week.
*more sessions available on digitalwpc.com
Multiple Attendee DiscountsTake advantage of registering three (3) to ten (10) representatives from your company and receive a US$400 refund for each registration. Learn more at www.digitalwpc.com.
Can't come for the whole event?
· All Access/Full Conference Pass - $1795
· 2 Day Pass* - $995
· 1 Day Pass - $650 (I recommend you attend Thursday for the US Track if you select this option)
· Hands-On-Labs Pass - $295
· Expo Only Pass - $150
· Business Leadership One Day Event Pass - $595.
To learn more about each of these options click here
WPC 2010 Expo Showcase your business to 10,000 Microsoft partners from around the world at the WPC Expo. Download the brochure and visit www.digitalwpc.com/Exhibitors.
2-DAY PASS - U.S. partner tracks and sessions are now posted on the conference website! Check out what's being offered to help you grow your business with Microsoft.
Wednesday, July 14th: A few Sessions to choose
Annuity and Renewal Come to this unique interactive session to learn how to position the Microsoft Open Value Licensing Program to maximize your sales potential.
Igniting the "S" In SMB- New Cloud Offerings for the Innovative Small Business This session is for cutting-edge partner sales teams intending to demonstrate the value of voice, data, presence, and business productivity resources available in the Cloud.
The Art of Improving Business Insight with SMB Customers The database is an essential ingredient of the solutions that small to medium business (SMB) customers purchase, and Business Intelligence is just one of the ways you can sell the database with your customers. With Microsoft's platform, you can help your customers implement BI reports faster and at a lower cost.
Windows Intune: Amplify, Simplify, Satisfy PC Management in the Cloud Microsoft recently announced Windows Intune, a new solution that brings together cloud services for PC management and malware protection, a Windows 7 upgrade subscription, and the Microsoft Desktop Optimization Pack. In this session, learn how Windows Intune can help you grow your business while providing greater value to your customers at a lower cost to you.
Telecommunications in the Cloud: What It Means for Service Provider Operations If you're a service provider working with communication companies and want to know industry trends, this is the session for you. An industry analyst talks to partners about how the move to cloud and online services is impacting the telecommunications industry.
Thursday, July 15th: A few Sessions to Choose
US Central Region EPG and SMS&P FY11 Strategy and Awards Join Central Region EPG and SMS&P regional vice presidents for an engaging hour as they showcase some of our partners' best practices and most compelling success stories and provide a high-level strategy for maximizing your partnership with Microsoft in FY11.
Through Disti tPAM Managed Partner Appreciation Luncheon Exclusively for Disti-tPAM managed partners, in this roundtable session and appreciation lunch we'll review FY10 results, celebrate wins, discuss go-forward plans, and provide you a unique opportunity to interact with our executive team in an open tPAM managed partner Q&A session.
Best Practices in Increasing Profit and Reach in the Emerging Cloud Computing Marketplace Attend this session to learn how you can increase profit and reach in the emerging SaaS and Cloud Computing market place. Hear best practices from partners and Microsoft experts who are leading the charge.
FY11 Small Business Conversations Find out what pain points Small Businesses consistently express to Microsoft and the corresponding conversations Microsoft is planning to have with these businesses in FY11 that will address these pain points and solve their technology needs.
Grow Your Business with Business Intelligence Learn how the top spending priority for CIOs four years running is maximized by the use of our latest launch products, Microsoft SharePoint 2010, Microsoft Office 2010 and Microsoft SQL Server 2008 R2.
Introduction to Microsoft's US Local Engagement Team Microsoft has developed an innovative approach to help our partners thrive in this challenging economic environment. Come hear how partners can extend their reach and increase revenue by teaming up with a variety of other companies to multiply their marketing impact.


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Are you Ratko Lasica?Claim your profile
Publications (21)34.73 Total impact
Article: PM099 Clinical presentation and prognosis of patients with acute aortic intramural hematoma03/2014; 9(1):e81. DOI:10.1016/j.gheart.2014.03.1500
Article: Efficacy and safety of tirofiban-supported primary percutaneous coronary intervention in patients pretreated with 600 mg clopidogrel: results of propensity analysis using the Clinical Center of Serbia STEMI Register.[Show abstract] [Hide abstract]
ABSTRACT: Studies with platelet glycoprotein IIb/IIIa receptor inhibitors (GPIs) showed conflicting results in primary percutaneous coronary intervention (PPCI) patients who were pretreated with 600 mg clopidogrel. We sought to investigate the short- and long-term efficacy and safety of the periprocedural administration of tirofiban in a largest Serbian PPCI centre. We analysed 2995 consecutive PPCI patients enrolled in the Clinical Center of Serbia STEMI Register, between February 2007 and March 2012. All patients were pretreated with 600 mg clopidogrel and 300 mg aspirin. Major adverse cardiovascular events, comprising all-cause death, nonfatal infarction, nonfatal stroke, and ischaemia-driven target vessel revascularization, was the primary efficacy end point. TIMI major bleeding was the key safety end point. Analyses drawn from the propensity-matched sample showed improved primary efficacy end point in the tirofiban group at 30-day (OR 0.72, 95% CI 0.53-0.97) and at 1-year (OR 0.74, 95% CI 0.57-0.96) follow up. Moreover, tirofiban group had a significantly lower 30-day all-cause mortality (secondary end point; OR 0.63, 95% CI 0.40-0.90), compared with patients who were not administered tirofiban. At 1 year, a trend towards a lower all-cause mortality was observed in the tirofiban group (OR 0.74, 95% CI 0.53-1.04). No differences were found with respect to the TIMI major bleeding during the follow-up period. Tirofiban administered with PPCI, following 600 mg clopidogrel pretreatment, improved primary efficacy outcome at 30 days and at 1 year follow up without an increase in major bleeding.03/2014; 3(1):56-66. DOI:10.1177/2048872613514013
Article: Simple Risk Algorithm to Predict Serious Bleeding in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention - RISK-PCI Bleeding Score -[Show abstract] [Hide abstract]
ABSTRACT: Background: Bleeding is a potentially catastrophic complication after primary percutaneous coronary intervention (PPCI). It occurs most frequently within the first 30 days following the intervention. The aim of this study was to generate a simple and accurate risk model for the prediction of bleeding after PPCI. Methods and Results: The training set included 2,096 patients enrolled in the RISK-PCI trial. The model was validated using a database of 961 patients enrolled in the ART-PCI trial. Bleeding was defined as type ≥3a bleeding according to the Bleeding Academic Research Consortium definition. Multivariate logistic regression was used to evaluate the predictors of outcome. A sum of weighted points for specific predictors was calculated to determine the final score. The model included 5 independent predictors of 30-day bleeding: gender (female); history of peptic ulcer; creatinine clearance at admission (<60ml/min); hemoglobin at presentation (<125g/dl); and Killip class >1 heart failure at admission. The model showed good discrimination and calibration for the prediction of bleeding in the derivation set (C-statistic, 0.79; goodness of fit, P=0.12) and in the validation set (C-statistic, 0.76; goodness of fit, P=0.37). Patients were classified into 3 risk classes and the observed incidence of 30-day bleeding of 1.0%, 3.5% and 10.7% corresponded to the low-, intermediate- and high-risk classes, respectively. Conclusions: A simple risk model was developed that has a reasonably good capacity for the prediction of 30-day bleeding after PPCI.Circulation Journal 04/2013; 77(7). DOI:10.1253/circj.CJ-12-1177 · 3.69 Impact Factor
Article: Usefulness of the RISK-PCI score to predict stent thrombosis in patients treated with primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: a substudy of the RISK-PCI trial.[Show abstract] [Hide abstract]
ABSTRACT: Stent thrombosis (ST) is an important cause of death after primary percutaneous coronary intervention (pPCI). This substudy aimed at evaluating the usefulness of the RISK-PCI score, originally developed for the prediction of 30-day major adverse cardiovascular events, to predict the occurrence of ST after pPCI. We analyzed 1972 consecutive patients who underwent pPCI with stent implantation between February 2007 and December 2009. Early ST (EST), late ST (LST), and cumulative 1-year ST (CST) were the predefined end points. Definite, probable, and possible ST were included. Models discrimination and calibration to predict ST was tested using receiver-operating characteristics curves and the goodness-of-fit (GoF) test. Sensitivity analyses and 1000-resample bootstrapping were used to evaluate the model's performance. The rates of EST, LST, and CST were 4.6, 1.4, and 6.0 %, respectively. Compared with controls, the cumulative ST group was associated with much higher rates of adverse clinical outcomes at 30-day follow-up (adjusted odds ratio (OR) for death 6.45, adjusted OR for major bleeding 4.41) and at 12-month follow-up (adjusted OR for death 7.35, adjusted OR for major bleeding 4.56). Internal validation confirmed a reasonably good discrimination and calibration of the RISK-PCI score for the prediction of EST (area under the curve (AUC) 0.71, GoF 0.42), LST (AUC 0.69, GoF 0.36), and CST (AUC 0.70, GoF 0.22) after pPCI. ST after pPCI is associated with adverse 30-day and 1-year clinical outcomes. We conclude that the risk of ST could be accurately assessed using the RISK-PCI score, which might help in deciding upon measures aimed at preventing adverse prognosis.Heart and Vessels 09/2012; 28(4). DOI:10.1007/s00380-012-0276-z · 2.11 Impact Factor
Article: Impact of high post-loading platelet aggregation on 30-day clinical outcomes after primary percutaneous coronary intervention. The antiplatelet regimen tailoring after primary PCI (ART-PCI) trial[Show abstract] [Hide abstract]
ABSTRACT: BACKGROUND: Patients with high post-loading platelet aggregation (PPA) are at increased risk of stent thrombosis and death after primary percutaneous coronary intervention (pPCI). The objective of the present trial was to examine whether high PPA is associated with adverse clinical outcomes in pPCI patients whose therapy was modified in accordance with PPA. METHODS: We analyzed 961 consecutive pPCI patients who underwent pPCI between February 2008 and June 2011. High PPA was defined as PPA >50%, 24h after the loading dose. Patients with high PPA were treated with aspirin 300mg, clopidogrel 150mg or ticlopidine 500mg for 30days. The co-primary efficacy and safety end points at 30days were major adverse cardiovascular events (MACE) and major bleeding. RESULTS: We detected high PPA to clopidogrel and aspirin in 44.4% and 16.5% of patients, respectively. The rates of 30-day MACE (adjusted OR 1.76, 95% CI 1.05-2.97), definite subacute stent thrombosis (DSST, adjusted OR 2.15, 95% CI 1.09-4.22) and nonfatal infarction (adjusted OR 3.99, 95% CI 1.57-10.13) were higher in patients with high PPA to clopidogrel compared with responders. High PPA to aspirin was not associated with an adverse 30-day clinical outcome. Compared with high PPA patients who were not tailored, a significantly better outcome with respect to the primary end point was observed in the tailored group (OR 0.42, 95% CI 0.19-0.93). CONCLUSION: High PPA to clopidogrel was an independent predictor of 30-day adverse events after pPCI. Among high PPA patients, tailoring was associated with an improved primary outcome.International journal of cardiology 05/2012; 167(4). DOI:10.1016/j.ijcard.2012.04.129 · 6.18 Impact Factor
Article: Impact of the Combined Left Ventricular Systolic and Renal Dysfunction on One-Year Outcomes after Primary Percutaneous Coronary Intervention[Show abstract] [Hide abstract]
ABSTRACT: The aim of this study was to assess the impact of combined left ventricular systolic dysfunction (LVSD) and renal dysfunction (RD) on 1-year overall mortality and major adverse cardiovascular events (MACEs) (comprising cardiovascular death, nonfatal renfarction, target vessel revascularization, and nonfatal stroke) in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention (pPCI). One thousand three hundred ninety eight patients with first myocardial infarction, undergoing pPCI were divided into four groups according to the presence of LVSD (ejection fraction [EF] <40%) and/or baseline RD (estimated glomerular filtration rate <60 mL/min per m(2)): Group I (no LVSD and no RD); Group II (LVSD, no RD); Group III (RD, no LVSD); Group IV (LVSD + RD). One-year mortality rates in Groups I, II, III, and IV were 2.6%, 15.2%, 10.6%, and 34.2% and 1-year MACE rates were 5.7%, 19.5%, 17.1% and 35.7%, respectively. Patients in Groups II, III, and IV had an increased probability of 1-year overall mortality and MACE as compared to Group I. Overall mortality: Group II HR 2.1 (95% CI 1.1-4.2); Group III HR 2.1 (95% CI 1.1-4.1); Group IV HR 4.8 (95% CI 2.4-9.4); MACE: Group II HR 2.2 (95% CI 1.1-4.2); Group III HR 2.2 (95% CI 1.1-4.3); Group IV HR 5.1 (95% CI 2.6-10.1). The LVSD-RD combination was the strongest independent predictor for 1-year outcomes. The LVSD-RD combination is associated with an approximately five-fold increase in 1-year overall mortality and MACE after pPCI. The evaluation of the renal function in patients with LVSD represents a simple method which enables a more precise stratification of the risks related to the occurrence of adverse events in long-term patient follow-up.Journal of Interventional Cardiology 11/2011; 25(2):132-9. DOI:10.1111/j.1540-8183.2011.00698.x · 1.32 Impact Factor
Article: Incidence, predictors, and 30-day outcomes of new-onset atrial fibrillation after primary percutaneous coronary intervention: insight into the RISK-PCI trial[Show abstract] [Hide abstract]
ABSTRACT: Limited data exist about the prognostic significance of new-onset atrial fibrillation (AF) after contemporary primary percutaneous coronary intervention (pPCI). The objective of this study was to identify the incidence and predictors of new-onset AF and associated adverse 30-day outcomes in AF patients who underwent pPCI. We analyzed 2096 patients undergoing pPCI after pretreatment with 600 mg clopidogrel. Composite 30-day major adverse cardiovascular events were the primary end point. A logistic regression model was developed to identify risk factors for the occurrence of AF and prediction of its impact on 30-day outcomes. AF occurred in 6.2% of patients. Older age, Killip >1 heart failure at admission, systolic blood pressure of greater than 100 mmHg at admission, creatinine clearance greater than 60 ml/min, preprocedural infarction-related artery occlusion and postprocedural thrombolysis in myocardial infarction flow less than 3 were identified as independent predictors of the occurrence of AF. Rates of 30-day major adverse cardiovascular events [adjusted odds ratio (OR) 2.39, 95% confidence interval (CI): 1.47-3.87] and 30-day death (adjusted OR 2.67, 95% CI: 1.46-4.89) were higher in AF patients compared with patients without AF. A trend toward higher rate of ischemia-driven target vessel revascularization was observed in the AF group (adjusted OR 2.61, 95% CI: 0.82-8.39, P=0.10). New-onset AF after pPCI is associated with adverse 30-day outcomes. Accurate prediction of AF after pPCI might help deciding a more aggressive treatment approach aimed at preventing the adverse prognosis of these patients.Coronary artery disease 11/2011; 23(1):1-8. DOI:10.1097/MCA.0b013e32834df552 · 1.30 Impact Factor
Article: Predicting 30-day major adverse cardiovascular events after primary percutaneous coronary intervention. The RISK-PCI score[Show abstract] [Hide abstract]
ABSTRACT: BACKGROUND: Identification of patients at risk for major adverse cardiovascular events (MACE) might help selecting candidates for aggressive treatment or early discharge after primary percutaneous coronary intervention (pPCI). METHODS: The RISK-PCI is an observational trial of 2096 consecutive patients who underwent pPCI between 2006 and 2009, randomly allocated to derivation and validation sets with a set ratio of 80% to 20%. Thirty-day MACE comprising death, nonfatal reinfarction and stroke was the primary end point. Multivariable logistic regression was used to determine the independent predictors of outcome. A sum of weighted points for specific predictors was calculated to define the final score. RESULTS: The RISK-PCI score comprised 12 independent predictors of 30-day MACE, with a graded 125-fold increase in the primary end point with increasing risk score from ≤1 to ≥15. The model showed good discrimination and calibration for the prediction of 30-day MACE (c-statistic 0.83, goodness-of-fit p=0.72) and 30-day death (c-statistic 0.87, goodness-of-fit p=0.56). Bootstrapping with 1000 resample confirmed the stability of the model's performance. Patients were classified into risk classes, with the observed incidence of 30-day MACE of 1.9, 5.9, 13.3 and 39.4% in the low, intermediate, high and very high-risk classes, respectively. An 18-fold graded increase in the primary end point was observed between patients in a low risk class and those in a very high risk class. CONCLUSION: We derived a novel risk model to predict 30-day MACE after pPCI, which might help clinician decide the most appropriate treatment in accordance with the patient's risk profile.International journal of cardiology 06/2011; 162(3). DOI:10.1016/j.ijcard.2011.05.071 · 6.18 Impact Factor
Article: The importance of defining serum MMP-9 concentration in diabetics as an early marker of the rupture of atheromatous plaque in acute coronary syndrome.[Show abstract] [Hide abstract]
ABSTRACT: Acute coronary syndrome (ACS) is the main cause of mortality in diabetics. Acute myocardial infarction (AMI) in diabetics is much more often than in non-diabetics. MMP-9 activity could ease the formation of atherosclerosis, destabilization and plaque rupture as well as thrombocyte aggregation. THE AIM OF THIS STUDY IS TO EXAMINE: MMP-9 defining in serum in diabetics; the impact of diabetes mellitus on atherosclerosis and MMP-9 level; relation between serum values of MMP-9 and markers of glycoregulation and lipid status, respectively. RESULTS: The greatest concentration of both total and active MMP-9 serum has been noted in diabetics group with ACS. Both total and active MMP-9 values, in group with diabetes and ACS showed significantly important difference regarding the values in control group. Total and active MMP-9 showed statistically important correlation between the values of glycated hemoglobine A1c (HbA1c) and inverse correlations with values of subfraction HDL3.Active MMP-9 showed statistically important inverse correlation with value of HDL cholesterol. IN CONCLUSION: According to the results, it has been thought that active MMP-9 shows a certain degree of atherosclerotic changes on blood vessels better than total MMP-9. MMP-9, active one, could present an early marker of atherosclerosis, especially on coronary blood vessels, in diabetics with type 2.Acta Physiologica Hungarica 03/2011; 98(1):91-7. DOI:10.1556/APhysiol.98.2011.1.11 · 0.75 Impact Factor
Article: Prognostic significance of the occurrence of acute heart failure after successful primary percutaneous coronary intervention.[Show abstract] [Hide abstract]
ABSTRACT: Acute heart failure (AHF) has an adverse impact on short- and long-term outcomes in patients with acute ST-elevation myocardial infarction (STEMI). The aims of the present study were to determine independent predictors for the occurrence of AHF during hospitalization and to assess the impact of AHF on 30-day and 1-year outcomes in patients with STEMI who were successfully treated with primary percutaneous coronary intervention (pPCI). The study included 1,074 consecutive patients with STEMI who had no signs of heart failure (HF) at admission (Killip class I) and were treated with successful pPCI. Successful PPCI was defined as postprocedural TIMI 3 grade flow. Acute HF developed in 11.1% patients during hospitalization, which was predominantly mild to moderate (Killip classes II and III). Independent predictors for the occurrence of AHF were: anterior infarction, peak creatinine-kinase (CK) > 2,000 U/L and 3-vessel coronary disease. 30-day and 1-year mortality rates were significantly higher in patients with AHF compared to patients without AHF. AHF during hospitalization was an independent predictor of 30-day mortality (hazard ratio [HR] 10.5) and 1-year mortality (HR 4.4). Even after successful pPCI, the occurrence of AHF during hospitalization remains an independent predictor of 30-day and 1-year mortality.The Journal of invasive cardiology 07/2010; 22(7):307-11. · 0.82 Impact Factor
Article: Development and Validation of a Risk Scoring Model to Predict Net Adverse Cardiovascular Outcomes after Primary Percutaneous Coronary Intervention in Patients Pretreated with 600 mg Clopidogrel: Rationale and Design of the RISK-PCI Study[Show abstract] [Hide abstract]
ABSTRACT: No comprehensive primary PCI (pPCI) risk model to predict net adverse cardiovascular events (NACE) has been reported with the use of clopidogrel 600 mg, which is now considered the standard loading dose. The primary hypothesis of the RISK-PCI trial is that an accurate risk prediction may be achieved by using clinical, angiographic, and procedural variables available at the time of intervention. The present single-center, longitudinal, cohort study will include 1,750 consecutive patients with ST-elevation myocardial infarction (STEMI), undergoing pPCI after pretreatment with 300 mg aspirin and 600 mg clopidogrel. The primary end-points of the trial (NACE) include major adverse cardiovascular events (MACE) and major bleeding. A logistic regression model will be developed to predict 30-day and 1-year NACE after pPCI. A risk score derived from study set data will be validated using validation set data. Until June 1, 2008, 1,166 patients have been enrolled. Thirty-day follow-up is available in 1,007 patients. The RISK-PCI study is designed to develop an accurate risk scoring system, using variables available at the time of intervention, to predict long-term adverse outcomes after pPCI.Journal of Interventional Cardiology 07/2009; 22(4):320-8. DOI:10.1111/j.1540-8183.2009.00476.x · 1.32 Impact Factor
Basic & Clinical Pharmacology & Toxicology 06/2009; 105(s1):53. · 2.29 Impact Factor
Article: Carvedilol Increases Copper-Zinc Superoxide Dismutase Activity in Patients with Acute Myocardial Infarction[Show abstract] [Hide abstract]
ABSTRACT: Balanced and coordinated antioxidant defence enzyme activities are of utmost importance for correct physiological function and for shielding against unwelcome pathological conditions. We determined the activities of copper-zinc superoxide dismutase (CuZnSOD), catalase, glutathione peroxidase and glutathione reductase in erythrocytes isolated from patients receiving different therapy (streptokinase alone or in combination with metoprolol or with carvedilol) for up to 168 hr after starting treatment for acute myocardial infarction. We observed increased CuZnSOD activity in erythrocytes isolated from patients treated with streptokinase-carvedilol (after 6, 24 and 168 hr) and in erythrocytes isolated from patients treated with streptokinase-metoprolol (after 24 hr). In addition, positive correlation between CuZnSOD and catalase activities was found in erythrocytes isolated from patients that received streptokinase-carvedilol after 168 hr. As metoprolol does not react directly with hydrogen peroxide, it would appear that combined streptokinase-metoprolol therapy exerted its effects primarily via by beta-blockade whereas combined streptokinase-carvedilol therapy appeared to function via both beta-blockade and direct antioxidant mechanisms.Basic & Clinical Pharmacology & Toxicology 09/2007; 101(2):138-42. DOI:10.1111/j.1742-7843.2007.00094.x · 2.29 Impact Factor
Article: Randomized active-controlled study comparing effects of treatment with cardeviol versus metoprolol in patients with left ventricular dysfunction after acute myocardial infarction[Show abstract] [Hide abstract]
ABSTRACT: Carvedilol has previously been demonstrated to be beneficial in patients with acute myocardial infarction (AMI) and left ventricular (LV) dysfunction. However, metoprolol has not to date been randomly evaluated in the same patient population. The objective of this study was to compare the effects of treatment with carvedilol versus metoprolol in patients with LV dysfunction after AMI. The study enrolled 313 high-risk patients with anterior AMI and LV ejection fraction of <45%, randomly assigned to treatment with carvedilol or metoprolol. Patients were followed-up for a mean period of 13.4 months. The primary end point was time to composite adverse events (t-CAE). The secondary end points were time to composite hard events (t-CHE) and health-related quality of life. No differences were found either in the primary end point of t-CAE or in the secondary end point of t-CHE. A significant benefit was observed in 4 of 8 health-related quality of life domains in the carvedilol group, with fewer carvedilol group patients being withdrawn from therapy in the hospital. Treatment with carvedilol, in comparison to that with metoprolol in patients with AMI and LV dysfunction, did not differ significantly in regard to the primary end point of t-CAE or to the secondary end point of t-CHE but resulted in better long-term quality of life and favorable early safety profile.American heart journal 08/2007; 154(1):116-22. DOI:10.1016/j.ahj.2007.03.049 · 4.56 Impact Factor
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ABSTRACT: There have only been a few studies of the chronobiological occurrence of acute aortic dissection (AAD), and most were international and multicentered. The aim of the present study, conducted at only one center, was to determine the most frequent daily, monthly, and seasonal occurrences of AAD. The study population included 204 patients (66.5% male) treated at our institute between January 1, 1998 and January 1, 2004. A significantly higher frequency of AAD occurred from 6:00 AM to 12:00 noon, compared with other time periods (P < 0.001). The results showed a significant circadian variation in AAD (P < 0.001) with a peak between 9:00 AM and 10:00 AM. No significant variation was found for the day of the week; however, AAD occurred most frequently on Wednesday and Monday. The frequency of AAD was found to be significantly higher during winter versus other seasons (P < 0.001). The analysis of monthly variations of the onset of AAD confirmed a peak in February (12.9%) and in January (12.3%). Similar to other cardiovascular diseases, AAD exhibits significant circadian and seasonal/monthly variations. Our findings indicate that the prevention of AAD, especially during the aforementioned vulnerable periods, is possible by adequate tailoring of the treatment of hypertension, which is the main AAD predisposing factor.International Heart Journal 08/2006; 47(4):585-95. DOI:10.1536/ihj.47.585 · 1.13 Impact Factor
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ABSTRACT: We have previously shown the protective effects of both Larginine and phystigmine in an experimental model of severe hemorrhagic shock, when these substances were used as monotherapy. It was of interest to investigate whether the combination of L-arginine (300 mg/kg, i.v. bolus) and physostigmine (0.07 mg/kg, i.v. bolus) could produce further beneficial cardiovascular and/or metabolic effects in anaesthetized hemorrhaged rabbits (intermittent bleeding; 40% of the estimated blood volume for 15 min). Selected cardiovascular and biochemical parameters were assessed before bleeding and at several points up to 60 min after the end of bleeding. Drugs were injected 1-2 min after the end of bleeding (Phy-group) or 10 min later (L-Arg+Phy-group). Control rabbits received the corresponding volumes of saline only (0.6-2.0 ml; S-group). Physostigmine (0.07 mg/kg) produced a rapid and sustained increase in mean arterial pressure, the effect being attenuated in L-argininepretreated rabbits (Phy- and L-Arg+Phy-group respectively). The beneficial effecs of L-arginine on heart rate and hemoglobin oxygen saturation in venous blood were not completely lost in rabbits of the LArg+ Phy group, and such a combination partially improved acid-base status (decrease in PaCO2 in arterial blood) and produced further hemodilution (decresase in hematocrit) 15-60 min after the end of bleeding. However, the combination of L-arginine and physostigmine does not offer any significant advantage over the monotherapy with these drugs in hemorrhagic shock.Acta veterinaria 01/2006; DOI:10.2298/AVB0603157T · 0.13 Impact Factor
Vojnosanitetski pregled. Military-medical and pharmaceutical review 10/2005; 62(9):661-70. DOI:10.2298/VSP0509661S · 0.27 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: Intramural haematoma is the precursor or the variant of a classical aortic dissection where hemorrhage occurs within the aortic wall (aortic media) and in absence of initial intimal tear. This entity looks like a classical aortic dissection, but it differs from it by its pathological characteristics. Although the intimal tear is absent, the prognosis of patients with intramural haematoma is similar to that of patients with classical aortic dissection; it is therefore very important for these patients to be early diagnosed. With a development of modern non-invasive diagnostical techniques the intramural haematoma is more often diagnosed and actually amounts at 10 to 30% of all acute aortic syndrome cases. Clinical characteristics and death rate of patients with intramural hematoma are similar to those of patients with classical aortic dissection, especially when it is obvious that there is a considerable risk for intramural haematoma to complicate into aortic ulcer, aortic aneurysm or rupture. Since intramural haematoma comprehensive diagnostic technique does not exist, safe therapy has not been yet established. Future randomized studies and serial observation of patients with intramural hemorrhage are indispensable not only to clarify these patients' survival predictors but also to define a model of optimal therapy.Medical Archives 02/2005; 59(2):121-3.
Article: [Plasma and red blood cell superoxide dismutase activity in patients with different stages of essential hypertension].[Show abstract] [Hide abstract]
ABSTRACT: It has been suggested that superoxide dismutase (SOD) plays an important role in endothelial dysfunction in essential hypertension (EH), by competing with nitric oxide for superoxide, thus influencing nitric oxide bioavailability. To answer the question of whether endothelial dysfunction is consequence of altered SOD expression we determined SOD activity in patients with different stages of EH. In this study 45 EH patients and 25 normotensive subjects were included. EH patients were divided into the three groups according to the guidelines of European Society of Hypertension. SOD activity was determined spectrophotometrically in RBC and plasma of EH patients and controls. The results obtained have shown that all groups of EH patients exhibit lower SOD activity than control normotensive subjects. Significant correlation between SOD activity and both diastolic (p<0.05, r=-0.394) and systolic blood pressure (p<0.05, r=-0.356) was found. Lowering of SOD activity in patients with different stages of EH leads to inefficient detoxification of superoxide in EH. An excess of superoxide of both cellular and extracellular origin takes part in enhanced degradation of nitric oxide and altered vasodilation, and consequent endothelial dysfunction.Medical Archives 01/2005; 59(3):156-9.
Article: The influence of lidocaine and beta-blockers on L-NAME-induced potentiation of the isolated rat hemidiaphragm contractility[Show abstract] [Hide abstract]
ABSTRACT: L-NAME (1-10 mM, 30 min of incubation) potentiates the tension developed (Td) in the isolated rat hemidiaphragm stimulated by direct subtetanic electrical stimulation (OSES) (F = 14 Hz). The aim of our study was to investigate the possible modulatory effect of local anaesthetic (lidocaine) and beta adrenergic blockers, propranolol and atenolol, on the L-NAME- induced potentiation of isometric contractility (1C). Lidocaine (0.1 mM, 5 min incubation) did not change Td by itself. Also, in the presence of lidocaine (0.1 mM, 5 min incubation), the stimulatory effect of L-NAME (3 mM, 30 min incubation) was preserved. In contrast, lidocaine itself (0.1 mM, 30 min incubation) produced an increase of Td up to 50%. The incubation of the muscle with both lidocaine (0.1 mM, 30 min incubation) and L-NAME (3 mM, 30 min incubation) produced an almost additive stimulatory effects, up to 90% on Td. Propranolol itself (1 µM, 5 min incubation) did not change Td. In the presence of propranolol, L-NAME maintained the stimulatory effect on Td. Propranolol (1 µM, 30 min incubation) did not change Td itself, but abolished the stimulatory effect of L-NAME. Atenolol (1 µM, 30 min incubation) neither significantly changed Td nor L-NAME-induced potentiation of Td.Acta veterinaria 01/2005; 55(4). DOI:10.2298/AVB0504259S · 0.13 Impact Factor
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University of BelgradeBeograd, Central Serbia, Serbia
University Children's Hospital, Belgrade, SerbiaBeograd, Central Serbia, Serbia
Klinički centar Srbije
Beograd, Central Serbia, Serbia
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Our Precious Metals group is an industry leader in providing liquidity in gold, silver and platinum group metals through our fully integrated over-the-counter (OTC), physical and derivatives Precious Metals effort. With hubs in New York, London, and Dubai, our team delivers 24-hour desk coverage, knowledge and market insight to a wide range of clients. We are also one of the world's leading coin dealers and are authorized to represent several of the world's mints.
For further information, email us at firstname.lastname@example.com.
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Loopbuddy Prepared Themes
#1 Guest_Tadaeus_*
Posted 29 January 2014 - 10:03 AM
I would like to use LoopBuddy and want to know if my Theme is ready for this.
Tatami - http://www.elmastudio.de/wordpress-themes/tatami/
If not, which Themes can I use?
Thanks in advance
Posted 29 January 2014 - 11:54 AM
Thanks for your interest in LoopBuddy!
LoopBuddy will work with any theme that uses the WordPress Loop Standard. You can also use LoopBuddy in any theme's widget area. You can contact the theme developer and refer them to our codex for more input on compatibility with their theme.
All of our themes are compatible with LoopBuddy.
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#3 Guest_Tadaeus_*
Posted 30 January 2014 - 03:32 AM
thanks for your answer. I don´t know why but it´s hard to get information and reviews about LoopBuddy. I like the functionality a lot, but I need more information.
Is the styling with LoopBuddy responsive?
Why do I need to pay for 2 licences when I only need 1?
Is LoopBuddy compatible with other plugins like Gravity Forms, WPML?
Can i display posts in a loop by views or ratings?
May I see some showcases?
Thanks in advance, but I´m struggling whether to buy LoopBuddy or WP Views.
Best regars,
#4 Guest_Tadaeus_*
Posted 06 February 2014 - 08:06 AM
Posted 06 February 2014 - 10:16 AM
My apologies, it seems I missed your previous post.
The responsiveness is going to depend on your theme, not LoopBuddy.
We don't offer single license packages. This packages we do offer seem to work well for (at least most of) our customers.
I have not seen any conflicts with either of those plugins nor am I aware of any conflicts with other plugins, of course there could be.
LoopBuddy queries have several ways of filtering your posts, but by views or ratings isn't a current option.
Unfortunately I don't have a showcase for you, and I don't think you'd get very much from one. However, below is a link to our codex with tons of information including a one hour webinar.
Please let me know if you have any other questions!


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Over 30 area public school educators met with State legislators and representatives of Catapult Learning for a Legislative Luncheon on Friday, April 4, at the former Altus High School Library to discuss issues surrounding public education.
Senator Mike Schulz and Representative Charles Ortega sought input from teachers and administrators concerning Reading Sufficiency to present to Committee members at the State Capitol during the current legislative session.
Following a catered meal by La Plaza Catering, courtesy of Catapult Learning, educators gave feedback on Catapult Learning's "Literacy First" reading assessment program.
Several teachers and administrators praised Literacy First for being a "complete package" when compared to other reading assessments. The program keeps schools accountable and teachers completely informed on each student's performance level, and gives an accurate diagnosis and target area, explained Rivers Elementary School Principal Robbie Holder.
"It's important for us to tell our parents, 'This is what we're doing.' We're not playing a guessing a game with Literacy First," Holder said. "It's a complete package. When the Reading Sufficiency Act came along it fell right into place. I believe that it has truly made a difference because my school is so fluid at River's Elementary school. We have so many kids coming in and out that we've been able to diagnose and target kids who come to us from different countries, different school systems, and know exactly what we need to target in those kids help them read. It is the reason our reading program has become so successful over the years."
Eldorado Public Schools Superintendent Dr. Harold Hays commented about their use of the program when it was offered to their school under a 3-year grant several years ago.
"As we were implementing it each year, we were finding that this was really an exceptional program for classroom teachers and for the students," said Hays. "I wish they would put it back as a line item. If you have not at least investigated Literacy First, you need to take a strong look at that because it does work."
Washington Elementary School Principal Rene Long compared other reading assessments to Literacy First stating they don't provide as much diagnostic information or depth as Literacy First.
Senator Schulz and Representative Ortega were both active in the discussion.
"The comments today are dead on of what we need to hear," Senator Schulz said. "So when we go back… we can talk to them about the details of these programs and why they work."
Additionally, Schulz stated that the Rally For Education on March 31, went very well. Over 130 students, teachers and administrators met with Legislators at the State Capitol to discuss issues surrounding public education.
"The education community has allowed it's voice to be heard," Representative Ortega added about the education rally.
Currently, Altus, Lawton, Norman, and Still Water Public School Districts are the only schools in the State using the Literacy First program through a $455,000 competitive grant according to Catapult Learning Lobbyist Shawn Lepard. Altus implemented the diagnostic program approximately 14 years ago allowing teachers to detect reading deficiencies for grades K-3rd. The program was appropriated as a line item for $2.8 million in the State's budget until 4 years ago when the Department of Education implemented the REACH program. Lepard stated that they continue to ask legislators to restore the full amount for the program state-wide and increase the funding of the competitive grant.


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By GWEN SISSON
Becky Stockwell said she and her husband, Joe, enjoy sitting on a particular bench in the garden that provides a great view of the landscape.
The fungus (Rhizoctonia solani) commonly known as large patch (also referred to as brown patch) is the most troublesome lawn disease for many Southern lawns.
The monster tornadoes which gobbled up much of north Mississippi and Alabama on Wednesday were devastating, but folks in my town did the best they could to cope.
By RUTH MORGAN
For Starkville Daily NewsÂ
A reflection is an instant of being reflected...reflected light...like a mirror reflecting an image being produced by one thing or another.


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Gear Deals
Announcements of online & local sales, coupons, etc. Commercial posts OK, but ONLY if you are announcing a sale or coupon.
Announcements of online & local sales, coupons, etc. Commercial posts OK, but ONLY if you are announcing a sale or coupon.
|Gore-tex Active Shell $180
|New Products On Sale: Evernew, Aquamira, Equinox, Brunton, Etc.
|Golite Reed Pants
|WTB TT Hogback or BS Revolution 4P
|Esbit 12 pcs X 14 g $5.99 at LiteTrail, Plus New Items...
|Campmor Therm-a-Rest Sale
|Gore-Tex "boonie" hats
|Womens down vest - $30 at Costco
|MH conduit SL bivy $60 on Steepandcheap.com for 17 more minutes (18 oz. breathable bivy)
|wtb BPL cocoon
|WTB: Crampons, ice axe
|Jack Mountain Bushcraft - Free eBook Downloads This Week
|Eddie Bauer Serrano Primaloft Insulation jacket $85
|Nat Geo maps & no-name down jackets
|Pack for sale, only $59,750.00
|Nikwax, Baladeo, Granite Gear at the Clymb
|New LiteTrail Odor Proof Bags and Packliners - like NyloFume
|enLIGHTened equipment down quilt from $165
|July 4th: One Day Sale-20% Off
|GoLite Malpais Trinity rain jacket $79.99
|New Products
|Patagonia R1 Pullovers & jackets at 6pm.com - Women (all sizes) $35 - $46 free ship
|40% off at Sierra Trading Post - ends tonight
|All Stakes 25% Off for one week only!


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Roasting brings out cinnamon's spicy-sweet flavor. Add to muffins, apple pie and chocolate desserts. Also great in mole recipes and spice rubs for meats.
• Perfect for French toast, oatmeal or yogurt.• Also great in molé recipes and spice rubs for meat.• Sprinkle on fruit or stir into pancake, muffin or cookie batter.
Serves: 8Prep time: 20 mins
This product has no significant nutritional value.
This is the BEST cinnamon I have ever had! I love it in all my baked goods and shaking on at the table.
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The best cinnamon I have ever used in baked goods!


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Take each step of your way with ABB - from the mine to the product you market
Our approach covers the complete value-added production chain, from your mine to the product you market. We excel at merging equipment, skills and services to develop a complete customized solution that strengthens your entire operation - regardless of project size. You specify the requirements and we take the responsibility for creating an integrated solution that works smoothly and efficiently.
2015-04-30: State-of-the-art ring-geared mill drive solution to provide process efficiency and equipment reliability for Ferrexpo Poltava Mining's latest mine upgrade
2015-01-22: The new Knowledge Manager Production Scheduler supports plant managers to find the optimal production schedule by constantly adapting it to operational constraints
2014-12-11: The new service package includes two new modules GMDbeat and GMDfit to anticipate the behavior of grinding assets – analyzing the past and the present to predict the future
2014-12-03: End users, suppliers and partners from across the globe joined ABB for its ninth consecutive global mining networking event
One of the world's largest and cost-effective tungsten and polymetallic mines – Nui Phao in Vietnam – is coming into production now and is equipped with a vast range of locally supported ABB power and automation solutions to maximize productivity, energy efficiency and grid stability.


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Sandwich Monday: The Concrete
Purveyors of fine foods have any number of ways of showing them off. Auntie Anne's hands out free pretzel samples at the mall; McDonald's lets a princess sit on top of the Big Mac to show she can't feel a pea underneath.
At Ted Drewes in St. Louis, when they hand you your Concrete, they flip it upside down to show you it's so thick, it won't fall out of the cup.
If you're not familiar with the Concrete, it's a frozen custard confection, like a Dairy Queen Blizzard on crack. You can get it filled with anything, including crack.
Miles: The world would be a better place if this was what roads were paved with.
Ian: This is way better than the Loose Gravel. Which it turns out is actual loose gravel.
Peter: If they'd had these in the 1810s, Lewis and Clark never would have left St. Louis. They wouldn't have been able to move.
Ian: So the thing about these is you can flip them over and they don't fall out. Yet I can eat it easily with a spoon. Therefore my desire to have food in me is stronger than gravity.
Miles: In physics, there are five kinds of forces: strong, weak, electromagnetic, gravitational and — the strongest — gastrointestinal.
Peter: I like the Dark Matter flavor Concrete. You can't see or taste it, but it still makes you fat.
Robert: Slamming my face into this concrete is much more satisfying than that time in college after those tequila shots.
Miles: I'd like to be a victim of the mob that makes its cement shoes out of Ted Drewes' Concrete.
Eva: This makes me feel inferior — if someone turns me upside down, I fall.
Robert: It's delicious, but I think strengthening it with rebar goes a little too far.
Miles: Either way, I, for one, am now pro-crete.
Eva: I like knowing my dessert is there for me; my rock.
[The verdict: Is it delicious? Absolutely. Is it a sandwich? Of course it is. We stopped at Ted Drewes when we were in St. Louis to do Wait, Wait there a while back .... OK, let's be honest: We did Wait, Wait there so we had an excuse to go to Ted Drewes.]
Sandwich Monday is a satirical feature from the humorists at Wait, Wait ... Don't Tell Me!


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In an ordinary deck of cards there are four type of cards (club, spade, diamond and heart), and in each type there are face cards . So, total number of face cards are
Number of non – face cards in a deck of cards are
Therefore, odds in favour of drawing a face cards
Hence, the required odds in favour is .
Chegg is one of the leading providers of homework help for college and high school students. Get homework help and answers to your toughest questions in math, calculus, algebra, physics, chemistry, science, accounting, English and more. Master your homework assignments with our step-by-step solutions to more than 3000 textbooks. If we don't support your textbook, don't worry! You can ask a homework question and get an answer in as little as two hours. With Chegg, homework help is just a few clicks away.


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Pronunciation: smalamennska
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text: Texas A&M's Kenric McNeal watches as Oklahoma State's Justin Gilbert (4) recovers McNeal's fumble next to Markelle Martin (10) and Brodrick Brown (19) in the third quarter of their game Saturday in College Station, Texas. The fumble and recovery turned the tide of the game, leading OSU to a 30-29 win in College Station, Texas. Photo by Nate Billings, The Oklahoman


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State Police at Swiftwater are investigating a theft from a car at Shawnee Mountain in Smithfield Township.
The suspect rummaged through the car, stealing a platinum wedding band and a silver ring valued at $1,000.
Anyone with information is asked to contact police at 570-839-7701.
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Colette Bouchez
Douglaston, New York
I'm an award winning medical journalist with over two decades of experience reporting on women's health. Many of you may know me from my many years working with WebMD. I'm also the author of 8 books on women's health. I decided to specialize in women's health because I believe... Full Bio
Dear Colette,
I hereby requesting your vote to win 'People's Health Blogger Award'. Please see all my posts related to cancer in my blog. Thank you in advance for your help.
Best Regards,


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Lincoln Saving Bank is proud to announce the opening of a new LPO in West Glen on Monday, May 4!
Fraudsters are now pretending to be from credit/debit card companies' fraud departments, hoping to trick individuals into giving away their credit card security code. Be sure to be able to recognize what to look for when receiving these calls to keep your information secure.
Member FDIC
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Greg Mankiw
From Wikiquote
Nicholas Gregory Mankiw (born February 3, 1958) is an American economist and Professor of Economics at Harvard University.
|This People article is a stub. You can help Wikiquote by expanding it.
- After more than a quarter-century as a professional economist, I have a confession to make: There is a lot I don't know about the economy. Indeed, the area of economics where I have devoted most of my energy and attention — the ups and downs of the business cycle — is where I find myself most often confronting important questions without obvious answers.
- If You Have the Answers, Tell Me, The New York Times, May 7, 2011.
Principles of Economics[edit]
- The management of society's resources is important because resources are scarce. Scarcity means that society has limited resources and therefore cannot produce all the goods and services people wish to have.
- Ch. 1 : Ten Principles of Economics
- Economics is the study of how society manages its scarce resources. In most societies, resources are allocated not by an all-powerful dictator but through the combined actions of millions of households and firms. Economists therefore study how people make decisions: how much they work, what they buy, how much they save, and how they invest their savings. Economists also study how people interact with one another.
- Ch. 1 : Ten Principles of Economics
- There is no mystery to what an economy is. Whether we are talking about the economy of Los Angeles, the United States, or the whole world, an economy is just a group of people dealing with one another as they go about their lives.
- Ch. 1 : Ten Principles of Economics
- Principle 1: People Face Trade-offs…
Principle 2: The Cost of Something Is What You Give Up to Get It …
Principle 3: Rational People Think at the Margin…
Principle 4: People Respond to Incentives…
Principle 5: Trade Can Make Everyone Better Off…
Principle 6: Markets Are Usually a Good Way to Organize Economic Activity…
Principle 7: Governments Can Sometimes Improve Market Outcomes…
Principle 8: A Country's Standard of Living Depends on Its Ability to Produce Goods and Services…
Principle 9: Prices Rise When the Government Prints Too Much Money…
Principle 10: Society Faces a Short-Run Trade-off between Inflation and Unemployment
- Ch. 1 : Ten Principles of Economics
- Economists try to address their subject with a scientist's objectivity. They approach the study of the economy in much the same way a physicist approaches the study of matter and a biologist approaches the study of life: They devise theories, collect data, and then analyze these data in an attempt to verify or refute their theories.
- Ch. 2. Thinking Like an Economist
- To find a substitute for laboratory experiments, economists pay close attention to the natural experiments offered by history.
- Ch. 2. Thinking Like an Economist
- Assumptions can simplify the complex world and make it easier to understand.
- Ch. 2. Thinking Like an Economist
- The art in scientific thinking—whether in physics, biology, or economics—is deciding which assumptions to make.
- Ch. 2. Thinking Like an Economist
- The economy consists of millions of people engaged in many activities—buying, selling, working, hiring, manufacturing, and so on. To understand how the economy works, we must find some way to simplify our thinking about all these activities. In other words, we need a model that explains, in general terms, how the economy is organized and how participants in the economy interact with one another.
- Ch. 2. Thinking Like an Economist
- In this model [circular-flow diagram], the economy is simplified to include only two types of decision makers—firms and households. Firms produce goods and services using inputs, such as labor, land, and capital (buildings and machines). These inputs are called the factors of production. Households own the factors of production and consume all the goods and services that the firms produce.
- Ch. 2. Thinking Like an Economist
- The production possibilities frontier is a graph that shows the various combinations of output … that the economy can possibly produce given the available factors of production and the available production technology that firms use to turn these factors into output.
- Ch. 2. Thinking Like an Economist
- An outcome is said to be efficient if the economy is getting all it can from the scarce resources it has available. Points on (rather than inside) the production possibilities frontier represent efficient levels of production.
- Ch. 2. Thinking Like an Economist
- Microeconomics and macroeconomics are closely intertwined. Because changes in the overall economy arise from the decisions of millions of individuals, it is impossible to understand macroeconomic developments without considering the associated microeconomic decisions.
- Ch. 2. Thinking Like an Economist
- Positive and normative statements are fundamentally different, but they are often intertwined in a person's set of beliefs. In particular, positive views about how the world works affect normative views about what policies are desirable.
- Ch. 2. Thinking Like an Economist
- Making economic policy in a representative democracy is a messy affair—and there are often good reasons presidents (and other politicians) do not advance the policies that economists advocate. Economists offer crucial input into the policy process, but their advice is only one ingredient of a complex recipe.
- Ch. 2. Thinking Like an Economist


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Melissa Joan Hart is well on her way to starting her own baseball team.
The Melissa & Joey star, 36, gave birth to son Tucker Tuesday night. The little guy weighed in at 8 lbs., 5 oz. and joins big brothers Braydon, 4, and Mason, 6.
PHOTOS: Celebs Who Have Adopted Children
"Mom and Dad (Mark Wilkerson) are elated and can't wait to introduce him to his brothers," the couple told PEOPLE.
New episodes of Melissa & Joey premiere on ABC Family in the Spring of 2013.
PHOTOS: Cutest Celebrity Children


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Tuesday, May 26, 2015
As is well-known and frequently discussed, the gothically-inclined English woman of letters Daphne Du Maurier ({-Don't Look Now}, {-Rebecca}) also happened to be a lesbian, but virulently suppressed these inclinations given her beloved father's abhorrence to homosexual behavior - attitudes that Du Maurier imbibed and that gave her lifelong pangs of guilt and self-denial. She experienced two life-altering homosexual loves, however: an irreciprocal one for heterosexual Ellen Doubleday, the wife of her publisher Nelson Doubleday, and another for bisexual actress Gertrude Lawrence ({+Private Lives}), which Lawrence purportedly helped her consummate. As created for Du Maurier's centenary, Claire Beavan's BBC production Daphne dramatizes the connection between these two relationships; Beavan pulls from private letters and memoirs to depict the series of events by which Du Maurier (here played by Geraldine Somerville) fell into an impassioned love for Doubleday (Elizabeth McGovern), and how the unrequited nature of that love spurred her on to author a play about forbidden romantic longings, {-September Tide} - a play that, ironically, introduced her to the second great love of her life, Lawrence (Janet McTeer). In so doing, the film not only resurrects a long-buried and hidden part of Du Maurier's life, but explores the connection between life experiences and highly personalized artistic expression. ~ Nathan Southern, Rovi


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Botox WORTH IT RATING DETAILS
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Reviews from the Community
Botox: Help - South Africa
I had my botox done on 6/12/2012 on the 7/12/2012 left eye was looking smaller and felt heavy. I panicked and rubbed it. By the 8/12/2012 my left eye was completely shut I can not move my eyelid at all. It is now 16/12/2012 and no improvement. I phoned my doctor and he said it shouldnt last... READ MORE
Painless but Expensive - Edmonton, AB
I'm 34 and have noticed really bad crows feet lately. I was scared thinking I was going to get needles of toxin in my face but it was more scary thinking I look so old already so I sucked it up and went for it. #1 it doesn't hurt! don't not do it for fear of pain there was none. #2 it is alot of $$$ READ MORE
Bilateral Masseter Reduction - Atlanta, GA
I went to Dr Kim last week to get botox for a bilateral masseter reduction. He was very professional, helpful, and I am excited to see the results! It was clear that he tailored his approach to patients; spending more time with the woman before me who had dozens of questions and straight to the... READ MORE
Botox on my Jawline - Calgary, AB
Today, I have my first Botox done. Doctor prescribed 25ml to me. He put 3 needles on each side. The assistant told me it takes about 7 to 10 days to see the effect. I can't wait to see how my new jaw looks like. Hope it will be good. My head feels heavy after few hours injection.Jun 22,... READ MORE
Botox Brow Lift - Madison, WI
I turned 50 this year and have felt like my brows have really fallen which has made my upper eye lids sit very low, right on my eye lashes. This is true especially of my right brow and eye lid and I would draw the brow higher with pencil to make it look like it was at the same level as my left.... READ MORE
Botox 4 Days Ago - Waiting for Results...- Wailea, HI
It was not painful, I had no bruising, not really even any swelling to mention. I had red dots like bug bites on my forehead for 15 minutes, then you couldn't even tell. I am 43 and wanted a smoother youthful appearance. READ MORE
Botox: Cheapest in Adelaide AND Thailand
I've always wanted BOTOX and i waited for a while before i got it, i didn't really need it but at the age of 29 i find i have fine lines around my eyes and one in the middle of my forehead (between my eyes). I went to Thailand and got my breasts lifted and thought "what the... READ MORE
The Dreaded DROOP. Awful 1st Time Experience.
I'm a skin specialist working within a physician-directed clinic and one of the perks is that I am given free botox and fillers. (I entered $500 in the cost-section as this is what I would be paying were I not an employee as well as it being a required field.) I've always taken... READ MORE
Cow Wrinkle - Bangkok, Thailand
Hi Lady For cow wrinkle- We have to get it of For me, I looked uncomfortable, like as self-conscious when I meet some people. But Now!! I feel free!! Thank Doctor Thank high technology One month ago- How about my cow wrinkle? Let's talk. READ MORE
Never Again - Michigan
I went into the doc's to get juvaderm around my mouth, the clinician said that I should get botox around my eyes for my crows feet, i did not really want to but she kinda insisted, so I caved... Sorry I ever did that, my eyes look ok, but my smile is severly crooked, called them, they said... READ MORE
Botox for Eyes - Seoul, South Korea
I wanted to fix areas around my eyes which showed serious signs of aging. Most of my students thought I was 40 when I'm not even 30. I do not suffer from having a baby face. I went to the Teng Teng Skin Clinic in Shinsa(Seoul) South Korea and had Botox. The procedure was pain free and the... READ MORE
Botox in Masseters Resulting in Buccal Fat Pad Herniation - New York, NY
Pros: Last time I had this treatment done, I loved the result. I loved my more contoured, feminine jawline, and the atrophy of my masseters has really brought out my cheekbones. Cons: This time, I had the same amount injected, but it seemed to have caused an over-weakening of my left... READ MORE
Botox Was a Great Experience for Me! - Birmingham, AL
I spent $500 on 40 units of Botox and $1200 on 2 syringes of Juvederm. I love the results! I'm 48 years old and really wanted to do something to help with my aging appearance. I Received 40 units of Botox 5 days ago and I love it! I decided to only do the crows feet area and forehead. Now I... READ MORE
Worth the Wait-Takes Longer to Go into Effect than Dysport - Scottsdale, AZ
When I was a kid, I thought it was fun to be able to move my eyebrows separately because of my brow muscles. Then in my late 20's, the "11's" appeared. Not so fun. I'm talking about the wrinkles in between your brows you make when you get mad - and botox is awesome to... READ MORE
Love It! - Ireland
What can I say only that I love Botox! I am a 24 year old girl... I know very young for Botox but I had slight lines in my forehead that used to really annoy me, others say they could not see them but I could!!!! This was even worse when I wore make-up as it used to just sit into the lines and... READ MORE
Goodbye Wrinkles! - Bristol, CT
I am 41 years old and have been using Botox/Dysport for approx. 7 years. I really don't have many forehead wrinkles so I am mostly treating the glabellar area. (number 11 lines between the eyebrows). READ MORE
Botox - California
YAY,Botox! I look less stressed. What a simple solution. I know the effects will only last about 3 months.I've already made an appointment 3 months from now. I save a lot of money on all the store bought "remedies". READ MORE
Amazing Botox - Toronto, ON
I drove to Toronto Ontario just to receive Botox! Let me tell you it was totally worth the drive!!!! My doctor gave me the exact look I was going for, not overdone but natural and perfect! I have already sent several of my friends and family members to Dr Jugenburg and everyone has been... READ MORE
botox male 30 australia....
I have had botox around my eyex and also a filler in my cheeks, where they seemed to sink in alittle, the filler cost me about $1000 but the dr gave me a 10% discount cause I worked in Aged Care. The botox was about $300. I have had the botox twice now, the second time didnt look as good as... READ MORE
Never Again - Sydney, Australia
I had botox injected into my forehead I was just going to have my crows feet done but Doctor suggested forehead as well. Wish I had never had done it! the results were disastrous my entire brow has dropped making my eyelids drop so much that I cant even wear eye make-up and struggle to open my... READ MORE


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Handcrafted in a limited edition, this streamlined pair from BucketFeet has a lot more than a classically cool, white-hot body going for them. These stylish slip-ons let you walk in comfort with their fine yet durable canvas upper, padded ankle collar, removable molded latex insole, and sturdy rubber outsole. Rock these kicks at the after-office happy hour or your favorite rooftop bar.
Fit true to size. If you fall between sizes, order the next size down. Designed in Berkeley, CA.
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Frederick A. Jakobiec, M.D., D.Sc.
Harvard Medical School
Henry Willard Williams Professor of Ophthalmology, Emeritus Department of Ophthalmology
Massachusetts Eye and Ear
Director, David G. Cogan Ophthalmic Pathology Laboratory
Director, Eye Pathology Service
Director, Ophthalmic Pathology Fellowship
Senior Scientist
Center Affiliations
Research Summary
Dr. Jakobiec's clinical and research interests have centered on inflammation and tumors of the eye and surrounding tissues. As a clinician, he advanced cryotherapy for conjunctival melanomas and squamous carcinomas as well as concentrated on orbital tumors, particularly lymphomas, and was responsible for a 450 page chapter on orbital diseases in Spencer's four volume definitive textbook on Ophthalmic Pathology. Throughout his career, Dr. Jakobiec has focused much of his efforts on ophthalmic education. He has served a myriad of visiting lectureships and professorships at over 50 institutions and societies, and has received numerous awards and medals.
Frederick A. Jakobiec, M.D., D.Sc.
Mass. Eye and Ear
243 Charles Street
Boston, MA 02114
For patient inquiries, please visit
» Clinician Profile


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Women are more likely to use every social media platform except LinkedIn, according a Pew Research study. Every major network has seen an increase in users over the past year, with 73% of online consumers using at least one. Instagram in 2013 showed strong gains with 18-to-29-year-olds and African-Americans.
View Full Article in:Adweek
Media | Advertising | Marketing | Education | K-12 | Tech | Software & IT Services


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Early detection.
Accurate diagnosis.
Proper treatment.
You don't necessarily have to deprive yourself of your favorite foods when you are on a heart-healthy diet -- all you really need to do is update them to fit into your lifestyle. This healthy version of the classic Philly Cheesesteak adds more whole grains and vegetables while using leaner cuts of meat.
Time: 1 hour
Lean Rib-eye or Top-round, sliced thin
Tbsp yellow onion, julienned
Tbsp green pepper, cleaned, trimmed, and julienned
Tbsp mushrooms, sliced thin
tsp olive oil
tsp ground black pepper
Whole Wheat Steak Roll (6inch)
Tbsp Shredded Reduced Fat Provolone
Directions: Place the rib-eye in the
freezer for 30-45 minutes. Remove rib-eye and slice thin. Spray skillet with
cooking spray. Add onions, green peppers, and mushrooms. Sauté until onions are
golden brown and peppers and mushrooms are tender. In a separate skillet, brown
the sliced rib-eye in 1 tsp olive oil and pepper. Toast Steak Roll. Put a layer
of rib-eye on the bottom of the steak roll, top with provolone, onions,
peppers, and mushrooms.
Nutritional Analysis: Calories 450, Protein 35g, Fat 18g, Saturated Fat 5g,
Cholesterol 60mg, Carbohydrates 37g, Fiber 6g, Sodium 500mg, Vitamin A 2%,
Vitamin C 35%, Calcium 20%, Iron 20%
Variations: Other
variations to consider include the chicken cheesesteak (replace beef with
chicken to lower fat and sodium content), the pizza steak (a cheesesteak topped
with pizza sauce and mozzarella – note that this will add calories, fat, sodium, and
cholesterol), the cheesesteak hoagie (cheesesteak with lettuce and tomato), and the portobello cheesesteak (substitute grilled portobello mushroom slices for the steak).
photo courtesy of Eating Well.
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As Twitter Chairman Jack Dorsey prepares to unveil a new mobile payment system to politicos, the company seeks its first D.C.-based employee.
As Twitter co-founder and Chairman Jack Dorsey prepares to unveil a new mobile payment system to politicos, the company is on the lookout for its first Washington, D.C.-based employee.
The Government Liaison position appears to be the company's attempt at establishing stronger connections on Capitol Hill, as well as with political candidates using Twitter for their campaigns. "You'll help set the culture and approach of a fledgling public policy department and be an important part of our very small company," explains the job description, posted on Twitter's jobs site.
Twitter has become an increasingly integral component of political social media campaigns, so it comes as no surprise that the firm want to facilitate that usage, particularly if it means fortifying bonds with lawmakers and potential lawmakers who could eventually affect Twitter's business plans. "You'll help Twitter understand what we can do to better serve candidates and policymakers across party and geographical lines. You'll support policymakers['] use of Twitter to help them communicate and interact with their constituents and the world," notes the description.
"We are seeing strong growth of government, policy and political usage of Twitter and we want to help officials get the most out of our service to better communicate with constituents," a Twitter spokesperson told ClickZ in an e-mail.
The company hopes the new staffer will boost political use of its service, as well as develop best practices for it.
While Twitter is calling the Government Liaison gig its first job officially based in D.C., Dorsey has been establishing his own beltway connections. He plans to introduce a mobile payment system, Square, to Washington insiders and supporters of Tommy Sowers, a Democrat running in Missouri's 8th congressional district, at a campaign fundraiser tonight at a D.C. restaurant and bar.
Square is a magnetic device that works with iPhone, iPod touch, iPad, Nexus One, and Droid devices. It plugs into the headphone jack of the device, and acts like a tiny credit card swipe machine. Though it has obvious commercial potential, political campaigners are already buzzing about its uses for in-person fundraising.
"Online fundraising has always been hampered by the fact that the best asks are done face-to-face. Now we can have our people make those face-to-face asks...and actually be able to finish the conversion during the conversation," said Josh Koster, managing partner at digital consulting firm Chong + Koster, which is working with the Sowers campaign. "Square is the future of grassroots fundraising. It turns every canvasser into a fundraiser," he added.
According to tonight's event invite, the Sowers campaign is already using the Square system. "What better way to unveil the future of grassroots fundraising than through a fundraiser for a true grassroots candidate," declares the e-mail invitation. Howard Dean, former Vermont Governor and DNC Chairman, and Clinton White House staffer Paul Begala are also expected to attend.
Attendees can pay at the door through the Square system; the cost is $50 - or $25 for those 25 and under.
Chances are Twitter Government Liaison hopefuls could be in attendance at the Sowers fundraiser. According to the job listing, candidates should have at least three years experience working in government or with politicians.
Twitter is also hiring an Internet Marketing Manager.
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Kate Kaye was Managing Editor at ClickZ News until October 2012. As a daily reporter and editor for the original news source, she covered beats including digital political campaigns and government regulation of the online ad industry. Kate is the author of Campaign '08: A Turning Point for Digital Media, the only book focused on the paid digital media efforts of the 2008 presidential campaigns. Kate created ClickZ's Politics & Advocacy section, and is the primary contributor to the one-of-a-kind section. She began reporting on the interactive ad industry in 1999 and has spoken at several events and in interviews for television, radio, print, and digital media outlets. You can follow Kate on Twitter at @LowbrowKate.
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This Magic Quadrant examines leading digital commerce platforms that enable organizations to build digital commerce sites. These commerce platforms facilitate purchasing transactions over the Web, and support the creation and continuing development of an online relationship with a consumer.
Paid Search in the Mobile Era
Google reports that paid search ads are currently driving 40+ million calls per month. Cost per click is increasing, paid search budgets are growing, and mobile continues to dominate. It's time to revamp old search strategies, reimagine stale best practices, and add new layers data to your analytics.
June 10, 2015
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Rival factions in the Bharatiya Janata Party (BJP) got together on Friday when the party's renovated office was inaugurated by the party's state president, Sudhir Mungantiwar.
On the occasion, Mungantiwar urged the activists to keep the party united. The city office of the BJP now has a meeting hall, closed-circuit television (CCTV) cameras and video conferencing facility with links to the party's state unit office in Mumbai.
MLC Chandrakant Patil; BJP city president, Vikas Mathkari; MLAs Madhuri Misal and Bhimrao Tapkir; group leader of BJP in the Pune Municipal Corporation (PMC), Mukta Tilak: chairman of PMC standing committee, Ganesh Bidkar; former state minister, Dilip Kamble; former MP Pradeep Rawat; and former BJP city president, Vijay Kale were present.
Except for former city unit president, Anil Shirole and former city general secretary, Yogesh Gogawale, most of the local leaders of the Gopinath Munde faction attended the inauguration. Former city president and MLA Girish Bapat could not attend the event as he was out of town.
Vikas Mathkari was appointed city president in May. His appointment was strongly opposed by the Munde faction.
Mungantiwar said activists should keep the party united and take decisions in the interest of the common man.