text:
Compiling Successful IP Solutions for Software Developers
BakerHostetler's Tanya Forsheit Discusses Cloud Computing
Perla: LegalTech Startups Can't Fix BigLaw's Cyber-Security Problems
Competitor or Collaborator? What UpCounsel's Growth Means for BigLaw
Polsinelli Podcasts - Hedge Funds Now Using IPR Challenges
MacEwen on BigLaw's 'Hollow Middle', Shaky Vereins & Dentons in China
Special Report: The Hot-ish Swag at LegalTech New York 2015
Is the Patent Litigation Boom Coming to an End?
What is Bitcoin 2.0?
Will 2015 Bring New Regulations for Bitcoin Users?
Waldman: Stop Immunizing Websites That Allow Harassment
A Moment of Simple Justice - Snitching Ain't Easy
Data Privacy: The Next Frontier of Corporate Compliance
What are the Implications of Alice v. CLS?
After SoundCloud & Wunderlist: How Berlin plans to grow its startup scene
Diversity and Technology in Focus for Morgan Lewis's Incoming Chair
Diversity and Technology in Focus for Morgan Lewis's Incoming Chair
What Does the Supreme Court Ruling in Alice v. CLS Mean to a Software Entrepreneur?
A Moment of Simple Justice - Revenge Porn
Nov. 1 (Bloomberg Law) -- Bloomberg Law's Lee Pacchia runs through the week's most important legal news. Hurricane Sandy ravaged the East Coast of the United States and legal issues are beginning to emerge. Also, General...more
In This Issue:
- An Insider's View - More on Campaign Subplots
- The Congressional Calendar - So Much To Do, So Little Time –
- Heading Towards a Debt Ceiling Standoff, Part II
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text: Quick View save 37% Spirit Animals Starter Pack (Books 1-3) by Brandon Mull April 1, 2014 | Hardcover In stock online from $28.20 The first three titles from The New York Time''s Bestselling Series, Spirit Animals! Four children separated by vast distances all undergo the same ritual, watched by cloaked strangers. Four flashes of light erupt, and from them emerge the unmistakable shapes of incredible beasts a wolf, a… See Details $29.68 / $28.20 lowest price*was $44.97

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American Hustle takes home top SAG award
Published on Jan 20, 2014 6:42 AM
LOS ANGELES (AFP) - Crime caper American Hustle won the top film prize at the Screen Actors Guild (SAG) awards on Saturday, earning another big boost in Hollywood's all-important Oscars race.
Australian Cate Blanchett won best actress for her role in Woody Allen's Blue Jasmine, while Matthew McConaughey took home best actor for Aids activist movie Dallas Buyers Club.
Jared Leto won best supporting actor for his role in Dallas Buyers Club and best supporting actress went to Lupita Nyong'o in the harrowing drama 12 Years A Slave.
On the small screen, best drama went to cult series Breaking Bad and best comedy to Modern Family.
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Enter the More Than You Imagined Pinterest Contest for your chance to win amazing prizes from The New York Palace! #weddingcontest #newyorkweddings
2nd Prize – Congratulations Jourdan Hurst, the 2nd place winner of the "MORE Than You Imagined" Pinterest contest! You have won a dinner for two in The Gallery at Villard Michel Richard. We look forward to wining and dining you at our award-winning restaurant! Please contact email@example.com to redeem your dining certificate.
3rd Prize – Congratulations Danielle Nydam, the 3rd place winner of the "MORE Than You Imagined" Pinterest contest! You have won a complimentary bottle of champagne for two at Trouble's Trust. We are extremely excited to meet you! Please contact firstname.lastname@example.com to make reservations in the bar.
Thank you everyone for participating and please stay tuned for more upcoming contests!
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New York Palace Hotel weddings. Across from St. Patrick's Cathedral. #MOREwedding
A classic ceremony in the historic Villard mansion at The New York Palace


text:
Children's centre numbers fell by 800 after almost £500m of cuts, says Barnardo's
22 May 2015
Almost a quarter of children's centres across the UK have been forced to close or merge as a result...
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Peter Lewis, chief executive of the Institute of Fundraising, has given a lukewarm response to the government's long-awaited consultation on how to reform payroll giving, saying it does not go far enough to address fundamental problems in the system.
The consultation, which addresses how to make it easier to administer payroll giving and drive up the amounts raised through the scheme, makes a number of suggestions, including introducing standardised sign-up forms for all donors, employers and agencies.
However, Peter Lewis, chief executive of the Institute of Fundraising told civilsociety.co.uk that he was disappointed with how far the consultation goes:
"While this consultation addresses some specific issues, on which we will be engaging our members and responding in full, we are disappointed that it does not go further in trying to address the fundamental problems in the system which could make it work better for employers, donors and charities," he said.
The Institute's members have said the payroll giving system needs transformational reform based on the principles of universality, connectivity and portability. Lewis says these three principles are not addressed in the consultation.
The consultation stops short of recommending that offering payroll giving should become mandatory for all employers, saying it should remain a choice. And while it recommends creating "exit packs" for donors that stop giving through the scheme, to help them continue their relationship with the charity, Lewis says this does not go far enough to embed portability and connectivity into the scheme.
Joe Saxton, driver of ideas at nfpSynergy, was also underwhelmed by the consultation, saying the recommendation to open up payroll giving to the private sector was not a revolutionary change.
Currently payroll giving agencies must be charities, but the government has suggested scrapping this requirement.
Saxton said it would be very unlikely that the big companies who are already signed up to payroll giving, such as Tesco or the Royal Bank of Scotland, would switch payroll giving providers. "What would be their motivation?" he said.
Lewis also warned that opening up payroll giving to private providers would increase the burden for charities. "Multiple providers from a charity's point of view is not a good thing. They already have to deal with eight to nine agencies at a time. More would increase the complexity."
Elsewhere, John Low, chief executive of the Charities Aid Foundation, which pioneered the concept of payroll giving, welcomed the consultation.
"It is excellent news that the government is committed to making this important tax relief scheme work," he said. "With the right reform, payroll giving can play a huge part in encouraging more people to give and increasing the vital funds reaching charities at a time when demand for their work is higher than ever."
Sir Stephen Bubb, chief executive of Acevo, also welcomed the consultation and took credit for encouraging the government to launch it. "We welcome the Treasury's proposal to reform payroll giving, making it easier for donors to give regularly on a tax-free basis. This is what I called for in my letter to the Prime Minister earlier this month. There is massive untapped potential in payroll giving, and as a country we have to raise our game at making it work."
Simon Hopkins, finance director at the British Heart Foundation, said payroll giving was "ripe for change":
"Today's workforce is highly mobile and yet when someone changes jobs they must register for payroll giving all over again. It costs the sector an estimated £7m a year and is ripe for change."
And an NCVO spokesman said it was a good time for a review: "Payroll giving levels have hit a plateau in recent years so it's a good time to review what we can do to boost giving in the workplace. We're pleased the Treasury are taking action on this and look forward to contributing to the consultation."
The deadline for submissions to the consultation is 19 April 2013.
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Payroll giving should be opened up to private sector, says Treasury
Just five MSPs use payroll giving
Payroll giving reform must go beyond govt proposals, say sector bodies
Most government departments have below-average payroll giving rates
Government backs Payroll Giving Awards for two more years
Top payroll giving charities' use of payroll giving barely above average
Treasury considering 'pretty radical changes' to payroll giving
Payroll giving awards should not commend mediocrity
Payroll giving donations rise by 5 per cent
Government announces 'overhaul' of payroll giving
Government team to trial ways to encourage payroll giving
Is payroll giving out of steam?
Treasury to launch public consultation into payroll giving
Fewer than 2 per cent of MPs give via payroll
22 May 2015
Almost a quarter of children's centres across the UK have been forced to close or merge as a result...
21 May 2015
A child sexual abuse charity is set to close after it was overwhelmed with inquiries following the publicity...
20 May 2015
Skills for Logistics, a sector skills council charity, was driven into liquidation by its pension scheme...
22 May 2015
Charities considering changing their name must first find out exactly what their staff, beneficiaries...
22 May 2015
The Charity Commission has opened a statutory inquiry into a Bristol-based shelter after concerns were...
21 May 2015
Clic Sargent chief executive Lorraine Clifton, has announced that she will retire at the end of the year...
22 May 2015
Marie Curie set out to improve its use of digital after realising that it was "limiting its future"...
21 May 2015
Amnesty International UK has given street fundraisers virtual reality headsets so they can show the public...
20 May 2015
A review programme has been launched by think tank NPC to assess how to improve access to digital technology...
2013 Charity Shops Survey
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11 Feb 2016


text:
Silver VMBANNER
Extension Specific, VirtueMart extensions
Silver VM BANNER is a unique banner management solution for Joomla, which also works in conjunction with VirtueMart eCommerce Shopping Cart. This extension is developed mainly to support fundamental requirement to showcase targeted ads / banner to website users. This extension will be very much useful if you are having an eCommerce website and you are offering products with various types categories to your customers. Let's say if your customer is viewing a certain category of products, then it will be very much fruitful to show them relevant products for category the user is interested in. Silver VM BANNER extension resolves this problem by giving flexibility to the site administrators to create different groups of banners and then assign each group to a VirtueMart product category.
This extension can be configured to display banners in VirtueMart category landing page. Site Administrator can upload multiple images for each banner group. Silver VM BANNER extension works as the "showcase module" for the adverts / banners. This extension also gives flexibility to select horizontal or vertical position of the banner on category landing page.
Silver VMBANNER
- Version:
- 1.0
- Developer:
- Silver Touch Technologies Ltd
- Date added:
- Nov 19 2014
- License:
- GPLv2 or later
- Type:
- Paid download
- Uses updater:
- Includes:
- Compatibility:
OverallNot rated
FunctionalityNot rated
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DocumentationNot rated
SupportNot rated
Value for moneyNot rated


text:
Ramblings from another nerd on the grid
Gadget Links
Virtual Stuff
Windows Sites
Other Diversions
Submit an entry about your Windows 7 experiences and thoughts to the community. What are you looking forward to in Windows 7? Share a business or personal success, or cool and innovative feature. Your fellow community members will vote, so may the best story win.
Contest Location: http://it.toolbox.com/communities/microsoft-windows-7/contests
Contest Period: 11/23/09 to 02/23/10
This is a pretty easy contest to enter. No screencast or anything fancy this time around. Instead, tell us about your experience with Windows 7 for a chance to win a great prize.
See the contest site for the full rules. Sure wish I could enter. Good luck!!!
Sorry this is off topic, but I'm looking for a new laptop right now and my spec is simple, I want a 15 inch windows machine with an internal optical drive, and a dual or quad core processor that's as thin and light as a macbook pro. The Envy 15 appears to work (the i7 proceessor is quad core, right?), but why can't they get a slot loading dvd drive in that package size like apple can?
Nobody even seems to be trying. You get thick and clunky or no internal dvd.
You should probably check out the Dell Studio XPS. It has a slot load optical drive, i7, etc. Looks like a nice machine and it was my second choice for 1st prize in this contest.


text: The Q! Film Festival opened this year with a shift of focus. While the festival still predominantly features films that address issues faced by lesbian, gay, bisexual and transsexual (LGBT) people in Indonesia, founding director John Badalu wanted this year's offering to also address other issues faced by other minority groups — and through mediums other than film. Read more.


text:
Google™ voice typing is a feature that allows you to enter text using your voice. To use Google voice typing, you may need to turn the feature on. Open the Notification Panel by swiping your finger from the top of the screen to the bottom, and touch Settings > Language and input. Mark the box next to Google voice typing. Touch the Settings icon next to Google voice typing to edit the settings. Google voice typing allows you to Select input languages and Block offensive words.
To use Google voice typing when you are entering text, open the Notification Panel and touch Select input method > Google voice typing, or touch the Voice icon. Speak the words you want your device to type, and touch Done. The Voice icon will be shown on the keyboard by default. If the icon is not showing on your keyboard, touch and hold the Settings icon, and slide your finger to the voice icon.


text:
Reporting Instructions: DCF CORe Code 3324
Adam Walsh Foster/Adoptive Parent Fingerprinting
Report 100% of the costs for the processing of fingerprints through the federal Adam Walsh Protection and Safety Act, Public Law (P.L.) 109-248. The federal Adam Walsh Child Protection and Safety Act, Public Law (P.L.) 109-248, was signed into law on July 27, 2006, and became effective on October 1, 2006. Effective January 1, 2008 a provision of the law requires state agencies and their local governmental agencies or covered private agencies, to check all fingerprints of prospective foster and prospective adoptive parents. The fingerprints that are collected under this Act must be submitted to the Wisconsin Department of Justice and must be identified as submitted in compliance with the Adam Walsh Child Protection and Safety Act. The Wisconsin Department of Justice will process the fingerprints through the Wisconsin criminal information database and submit the fingerprints to the FBI for processing through the appropriate national criminal information databases. Costs reported on line 3324 will be paid up to the contract amount.
Costs reported over the contract amount may be moved by the county to line 3561 for payment if the 3561 is not fully spent.


text:
Holes that Must be Filled
2009-07-28 by Stephen Schuette
John's Gospel is filled with dialogue in which the communication never quite happens. It's clear, too, that the problem isn't with Jesus. It's John's way of inviting us into the depth of this mystery that is beyond our typical way of "seeing."
It reminded one colleague of this seminary exchange… The student, in frustration, confronted the teacher, "I keep trying to get a straight answer from you. Why can't you just give me a straight answer?" The teacher responded, "I'll give you a straight answer when you ask the right questions."
OK, so we've got a big hole in us. Everyone has it. And we keep trying to fill it. It's there in the child who is in the store and doesn't understand why they can't get something and the longing for it brings tears from a deeply injured self, even though the injury is only in the child's perception. It's in the dementia resident who travels from room to room in the institution in which they live collecting this and that. I think it was there in one who embezzled funds after losing a brother in Vietnam and a child to teen cancer. It's there when we confuse what we merely want with what we think we need.
And we can hoard even more than money or things. Some may hoard "rights and wrongs," that competitive scorecard that is an attempt to buttress a weak self-image. People can also hoard the injuries they've experienced, locking them in victimhood because at least that's something that identifies them.
I stand in awe of the claim that Jesus makes. "I am the bread of life. Whoever comes to me will never be hungry, and whoever believes in me will never be thirsty."
Give Us This Bread Always
2009-07-27 by Roger Talbott
Mitzi Minor's exegesis of John 6:24-35 in the Journal indirectly raises the question, can we begin to understand this passage unless we are hungry?
It's so easy for those of us, who know where our next meal is coming from, to judge this crowd's inability to understand the spiritual implications of the feeding of the 5,000. We say, patronizingly, "Of course, these people whom Jesus had fed the day before came back again looking for a free meal and they were put off because Jesus was trying to explain that they didn't live by bread alone, but by the Word that comes from God."
Me thinks we spiritualize too much.
I think we should take seriously John Crossan's contention that if the gospel is good news for the poor, then, at the very least, it is about bread.
If we take seriously the Ephesians' emphasis on unity in Jesus Christ, then the communion table becomes not just a symbol of Christ's presence, but a foretaste of that feast where everyone in the world has a place at the table and everyone is fed.
It's something we "see" just as clearly as the crowd saw the miracle of the feeding of the 5,000 and yet we, like them, do not really believe. A boy put his meager resources into the hands of Jesus and somehow it was enough. The Sign that Jesus talks about is the same Sign that we experience in those moments of unity when people come together and take care of each other.
There are moments people remember as miracles, of a sort: the evening the violent thunderstorm blew out the electricity, neighbors introduced themselves to each other as they moved tree limbs out of the road and patched damaged houses the best they could; the funeral that brought the estranged members of a family together and for a day or two the things that divided them didn't seem nearly as big as the grief that united them. Common need, common effort, common humanity leads to a kind of communion that we only wish we could experience once in awhile at church.
Over and over again, people in these circumstances ask, "why can't we always be like this?
Indeed during those few horrible days in mid-September 2001 some people ventured that everything had changed. Republicans and Democrats sang together on the Capitol steps. Liberals hung out American flags and conservatives volunteered for community service. Christians and Jews responded to acts of hatred toward Moslems by forming protective rings around mosques. Aid was distributed to those most directly affected by the destruction of the twin towers without regard to differences between CEO's and janitors. When people come together in genuine community, the maldistribution of bread is no longer a problem.
"Give us this bread always" is a prayer for a world that is no longer afraid of itself; a world that is not fragmented, but centered in a common humanity or the Common Human Being – the One we all know and love; whose face we see in the face of our brother or our sister.
"Give us this bread always" is a prayer for a world that no longer is afraid of tomorrow – that day when there will be no bread – that day, like the others we worry and worry about, that never comes if we break bread together on our knees."Give us this bread always" is a prayer for a world that is no longer afraid of gods who make distinctions based on creeds and rituals, but trusts in the God who gives gifts to us, not for our personal enrichment, but for the building up of the organic unity of humanity that Ephesians calls the Body of Christ.
We misunderstand this prayer if we think that once it is answered there is no longer any reason to pray, because the magic breadbox will supply our every need.
We only truly pray this prayer if we pray it as Jesus taught us to say: "Give us this day, our daily bread". It is in the constant renewal of our dependence upon God and in the constant renewal of community so imperfectly effected by the coming together of the Church around the Table – but effected none-the-less.
My process for sermon prep
2009-07-26 by Rina Terry
On Sunday evenings, I generally take a look at the lectionary texts for the upcoming week, begin to think about the overall worship design for the service, and, perhaps, write a Call to Worship, or Prayer of Confession.
L: In times like these we need a Savior
P: Jesus, you are our Solid Rock
L: In times like these we need an anchor
P: Our anchor holds when we grip the Solid Rock
L: In times like these we need the Bible
P: We're very sure, Jesus, that you are the One
L: In times like these we need not be idle
ALL: Our Rock is Jesus; yes, he's the One.
(based on In Times Like These, Ruth Caye Jones)
Since August 2nd will be Communion Sunday, what's floating through my head right now is the connection between receiving the bread of life (Johannine text) and building up the body of Christ (Epistle text).
2009-07-25 by David von Schlichten
Thank you to all who contributed posts this week. I hope others will scroll down to read them. There is much to work with here - a whole lot of splashing going on in the tub.
This Sunday I will finish a series on a journey through hell and then, the following Sunday, will begin a four-part series on a journey through heaven. In tomorrow's sermon (or whatever it is), my heroine, Pastor Katie Michael, will travel the River Styx, where she will see on the water a terrifying sight that she thinks is Satan but that turns out to be Christ coming to her rescue.
I look forward to your input, eternally
Yours in Christ,
David von Schlichten, Lectionary Blog Moderator
Slow-witted, Naive, and Scared
2009-07-22 by Tuck Taylor Bounds
John 6:1-21
"Slow-witted, Naïve, and Scared"
Poor Philip, he is not known for a quick mind or the boldest spirit. In fact, he is not known for much of anything. Philip didn't even seek Christ out as some of the others had, but Jesus had to go to Philip. No doubt Philip was a stable soul, a good man, dependable; but adventuresome, or risk-taking probably are not the adjectives to describe him. And it is Philip who Jesus asks: "Where shall we buy bread for these people to eat?" What is he thinking? We know the ones in our church, in our families, maybe it's even our very selves, who you do not ask their advice on issues of spending money – unless you want to be shut down immediately. Scripture is clear, Jesus asked it of Philip as a test. Would, could, Philip overcome his basic nature to move slowly, not take risks, see the world as it is, be practical? "Are you kidding me?" Philip says (in so many words), "we couldn't feed all these people even one bite even if we had 8 months of salaries." I wonder how long it took Philip to do that calculation! Seems his mind is quick in some areas – numbers, perhaps. But trusting the Lord who stood before him, the one who had been teaching and performing miracles for quite sometime now – well, Philip just couldn't quite get it. "No way", Philip says, "no way we can swing this one financially."
And then there's Andrew. I have an Andrew. He is the youngest of my 4 boys. The "baby", we call him, even though he is a full 8 years old! He is, by virtue of his age, more naïve than my other boys who are worldly and knowledgeable beyond their teenage years (at least in their minds). How they like to roll their eyes at the naïveté of their youngest brother – "right, Andrew, that'll work." Jesus' Andrew was much like mine, I think. We know he is young, Peter's younger brother, "here, he says, we have 5 loaves of bread and 2 fish", but then abashedly, "but that wouldn't work would it?"
And then we have the story of Jesus walking on the water. How frightening to the disciples: the slow-witted, the naïve as well as the adventurous, older and wiser ones. We have tamed Jesus in our minds: made him our fishing buddy, Jesus of Sunnybrook Farm. This text reminds us however, that when Jesus approaches it can, and often is, frightening.
What a group of followers Jesus has?! Slow-witted, naïve and scared. Which one are you? Certainly there is not one among us who doesn't relate to either Philip, Andrew or the scared disciples in that tossed about boat. Perhaps more than we would ever like to admit. And yet there is good news! Jesus knows all about Philip and his conservative, rather pessimistic view. He knows all about Andrew and his sweet desire to help and solve the problem. He knows all about the fear that each one felt in that tossed about boat. And for each one, Jesus provides what is needed. For Philip who cannot make his mind open up to the possibility of God's abundance in the midst of apparent scarcity, Jesus tests, teaches, and no doubt leads Philip to a stronger place of faith. For Andrew who wants to help, who sees the world in simplistic ways, Jesus takes Andrew's naïve sounding solution and brings forth a miracle. And finally, for the scared and frightened, Jesus provides assurance and salvation.
We are the hopelessly slow-witted, sometimes naïve, too often scared followers of Jesus. And it is enough – not because of who we are, but because of who Jesus is. Glory be!
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Mon-Fri: 7am-1am EST / Sat-Sun: 7am-11pm EST
ApplianceAmana Refrigerator
Level of DifficultyReally easy
Time to do repairLess than 15 mins
Age of Appliance5 - 10 years
this part basically pops in and out on each end of pantry lid. Took about 30 seconds to replace it! I was amazed with the quick service I received from your company too! It was shipped the same day I placed the order and received it the very next day! Way to go!!
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Part Number: PS2361958
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High, I'm a self taught artist who simply loves to paint!!!!!!!!!!!!!!
I accept Portrait & Equine commissions and work from photos supplied by you or I can take them myself.
My 2nd Solo Exhibition at Narellan Library HAS BEEN EXTENDED to January 31st 2015
Take a look at the Exhibition Catalogue here or email me for a copy.
You can also check out progress of my latest paintings on my Facebook Page
Winner Jai Rowell Award, 2011 Fishers Ghost Art Awards
Finalist in the international Inglis Equine Art Prize 2012 & 2013!!!!!! (there was no 2014 Inglis Art Prize..)
Finalist 2011, 2012, 2013 & 2014 Fishers Ghost Art Awards


text:
New to ePHOTOzine? Join ePHOTOzine for free!
Upload photos, chat with photographers, win prizes and much more for free!
Fantastic photo. I would have loved to see a larger version uploaded. ePHOTOzine will resize it for you, no need to resize to 600px anymore.
By: Slawek_Staszczuk
Very nice
By: MattB1987
I think it's pretty awesome as is.
By: karlfox
Really good stuff. If I was to be critical, the aerial has been partially brushed out and it's a little bit noticeable (but i am being critical). I imagine this was done during the removal of the rig. Still one of the best automotive photos I've seen on the site in a long time.
By: MattB1987
Against Terrorism with freedom of expression
it's a very cleaver idea.
By: clausaresu
I think you got it spot on. Brilliant concept.
By: mpnuttall
Thanks for uploading the unedited. Gives me a bit of insight how it would look with the pole and the level of editing required. I have to say, very impressive! Now if you can just find a Ferrari to stick it on
By: MattB1987
This photo seems to tell so many different stories.
By: Trevhas
pretty impressive. And here's me thinking they had some guy in a chaser car/bike doing shots like this. I'd love to see the un-edited version.
By: MattB1987
quite a nice photo. I think even using only the left half with a square crop would make an equally stunning composition.
By: carper123
How i miss the taste of those sooooooo much!
By: prabhusinha
I'm really enjoying seeing some classic american muscle on here.
By: arhb
It's a nice photo, however I would have loved to have seen a larger version uploaded. EPZ will resize it for you automatically.
By: davidcollins
evening falls.. nice skies over Aekingerzand (the Netherlands)
It's a really nice photo. I would have loved to have seen a larger version uploaded so we could see the photo in more detail
By: olafo
Hi Douglas,
By: douglasR
Hi Trev,
By: TrevBatWCC
The faces say it all. They really set the mood. It wouldn't be the same if they had smiles and joking faces.
By: john64
Thanks for all the comments so far! I'd love to see some others have a go. I put some links to a video tutorial on this topic:
By: davidburleson
Hi Terry,
By: terryxc
A really nice shot. It would have been even better if you had uploaded a larger version. ePHOTOzine will resize it for you automatically.
By: Mounters
version 2 is fantastic.
By: Growmore
These are really nice photos. however, it would be nice if you uploaded larger versions.
By: missmoon
This is a really nice photo, it's just a shame it wasn't uploaded a bit larger.
By: mlanda
I really nice photo. Would have been idea for the Panoramic feature.
By: mikesmith
Gran Turismo has a Photo mode which allows you to place the car in different scenes. Then you have the option to tweak the camera settings such as aperture/shutter, angle and some post processing. It's pretty close to taking a real photo.
By: davidburleson
It's a nice shot, it's a shame it's not uploaded at a larger size though.
By: douglasR
It's a really nice shot. It's a shame there isn't a larger version available.
By: victorburnside


text:
Our Members Say
- SirRichard
- Reviews: 3639
Imperio del Sol
Another good hostel in Yumani. I didn't stay here, just visited it while searching for a place to sleep and it seemed OK, cheap and clean, but was full.
Good views from the top of the hill.
Singles for 20-30 Bs
- AlbuqRay
- Reviews: 1795
La Estancia Ecolodge: Stay Overnight in Comfort
The Ecolodge is located near the village of La Estancia. The solar heated rooms are very clean and comfortable; the staff are friendly and the food good. I am guessing at the price since it was included in my tour. You must be able to walk/climb to reach it.
Although the Ecolodge is associated with American Express, other tour guides like mine (Mario Nina of Zig-Zag Tours in La Paz) are allowed to use it. The manager's name is Sonia.
The website shows three ways to get there. The shortest being a 30-45 minute walk up a steep hill. We actually took a fourth route. There is a trail along the ridge of the island that rises to over 13,000 feet. It is about four miles from Chincana to La Estancia, counting the shortcut over a small hill at the end. You would definitely want to be acclimated to the altitude, and have water and sunscreen before attempting this hike. See also a separate travelogue.
Unparalled views
- AlbuqRay
- Reviews: 1795
Bring Your Own Tent: Camp on the Beach at Challapampa
We walked by this beach on the way from Challapampa to the Chincana ruins. There are no facilities. I think they just pitched a tent at the end of the beach. It looked like they had been there a while though. If you look closely at the center of the picture, you may be able to see the gray walls of a hostel that is under construction (see below).
Magnificent view and plenty of fresh water
- annieruel
- Reviews: 244
Balcony of our motel lake Titicaca
The view was amazing... to the top of the island...a 360 of beautiful landscapes
there is a lot of insects...but...in a sleeping bag..it's ok.....hmmm...we ate trout of the lake for supper.
- Legolam
- Reviews: 5
Hotel Inti Wayra: Greatest view from a hotel window
The Hotel Inti Wayra, in Yumani on the Isla del Sol, is basic but fantastic nevertheless. There are shared facilities with (very) limited warm water, but friendly owners (who let you use their CD player in the dining room). It was 15 Bs a night in August 2003.
The hotel is perched at the top of the ridge above Yumani and has the most amazing views from all of its rooms. You can see right over Lake Titicaca to the Peruvian Andes, and the sunrise is to die for. It's definitely worth the lung-bursting climb up there.
- SirRichard
- Reviews: 3639
Templo del Sol
I stayed in this hostel in YUMANI (south of the island) cos I saw it at my LP guidebook, but there are many other similar as well, and even cheaper. But this was OK.
It is located on top of the hill in the village of Yumani. To get here, disembark the ferry from Copacabana at the first stop (south), by the "Inca stairs".
Then you gotta climb to the very top of the hill and ASK (it is a maze of alleys there).
The shower was shared and not very "luxurious", but enough. The rooms were big and quiet. And there is a terrace with wonderful views (see first pic of the Intro).
30 Bs (3,7 USD) for a single
- annieruel
- Reviews: 244
Templo del Sol: A la cima de la Isla
La vista vale la pena, este hostel esta muy lejos del barco pero cuando llegaste vas a olvidar el camino que es un poco difficil de subir sobre todo con una muchilla.
Al restaurante debes probar La trucha.... increible !!! tienen que probar por supuesto!
- SirRichard
- Reviews: 3639
My room at Templo del Sol
This was my room at the hostel, very good bed with a thick blanket (is very cold at nights there).
With good views and veeeeery quiet!
- AlbuqRay
- Reviews: 1795
Crillon Tours' Posada del Inca: Most Luxurious Hotel on Isla del Sol
Did not stay there. Just walked by it. It is just for customers of Crillon Tours.
It is in a historic hacienda next to the San Antonio church.
- AlbuqRay
- Reviews: 1795
No Name Yet: Future Hostel Near Challapampa
You walk by this structure on your way from Challapampa to the Chincana ruins. Supposedly, the family that runs the Posada del Inca in Challa is building it to be a hostel, although there was no activity the day we went by.
One thing for sure...the views will be spectacular.
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5 Feb 2011
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HARTFORD — One of Mason County's heroes will be honored this Saturday during a ceremony dedicating a bridge in his honor.
Cpl. John L. Gibbs was a local resident who was killed in the Korean Demilitarized Zone (DMZ) on July 21, 1967. At 10 a.m. Saturday, the bridge across Sliding Creek in Hartford on W.Va. 62 will be dedicated in his memory.
Guest speakers will be Dels. Scott Cadle and Jim Butler, who helped get the project completed and push legislation through to make the dedication happen. The public is invited to attend and colors will be presented by an elite unit of the West Virginia National Guard.
Gibbs was killed along with two other Americans while serving with the 2nd Battalion 23rd Infantry Battalion 2nd Infantry Division at a forward bunker on the DMZ. Since the armistice was signed ending the Korean War, between 300-400 Americans have been killed serving the U.S.
The official resolution states "Corporal John Leslie Gibbs was born on Nov. 1, 1944, one of 12 children born to the late Charles and Sadie Gibbs of Hartford. Whereas, Corporal John L. Gibbs entered the United States Army on Aug. 23, 1966. As a private first class, he was serving as a member of Company B, 2d Battalion, 23d Infantry, 2d Infantry Division, one of the forward elements of the United Nations Command enforcing the Korean Armistice of 1953. On July 16, 1967, PFC John L. Gibbs was in a foxhole south of the Korean Demilitarized Zone when his position was suddenly attacked by North Korean infiltrators under the cover of dense fog and darkness. A furious fire fight erupted and PFC John L. Gibbs and two of his fellow soldiers were killed."
On July 15, 1967, PFC John L. Gibbs was posthumously promoted to the grade of corporal, and was awarded the Purple Heart on Aug. 10, 1967, for wounds received in action in Korea resulting in his death. The bridge will now be known as the "U.S. Army Corporal John L. Gibbs Memorial Bridge."


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Galileo's downfall was simpler than theological debate: ideas such as his threatened Vatican power. Whilst of course he was proven right in his presumption - the Bible after all was written by people with no scientific knowledge to speak of - at the time it would have been seen as an attack on Church authority that had stifled learning for centuries.

The Church at the time liked their geocentric model despite being invented by a Classical Greek philosopher whose religion was of a veritable soap-opera of fractious gods and (oh dear, female) goddesses. It fitted both the simple arrogance of Man putting himself forward as God's pinnacle of creation and the mystical notion of perfectly circular orbits.

There's none of that nonsense in Genesis. Its unknown author at least realised he didn't know everything though he was probably only drawing on much older beliefs. It's more logical than other creation beliefs, even though its chronology is no more than metaphorical.

The science or religion debate is rather meaningless because you can believe in God and seek to understand the Universe. Science attempts to understand How and When and Where; not Why. It leaves the Why to the philosopher and the theologist.

Where it fails is in Creationism, an intellectually and theologically cowardly but cynically manipulative movement of minds as closed as the 15C Vatican's, which demeans science, Nature, the Bible, God and its own followers alike.

Whilst Lemaitre devised the theory, he didn't invent the name. It is credited to the British astronomer Fred Hoyle, ironically as he ridiculed the new idea as he was an ardent campaigner for the Steady State Theory of a never-starting, never-ending Universe. The phrase itself came from a BBC Radio continuity announcer who publicised a forthcoming programme on the matter by saying something like "... a sort of big bang."
I had no idea but this gnarly metric associated with General Relativity is mind-blowing:

http://www.ask.com/wiki/Lema%C3%AEtre%E2%80%93Tolman_metric?qsrc=3044

Thanks for making me look!
Ohhh!!!...cool...I love that show!!
He was also an astronomer and professor of physics.

Science and religion usually can't co-existing because they often contradict.

e.g. plants growing before the Sun

Sun revolving around the Earth

illness caused by demons and curses

Don`t have to be a dogmatic anything to understand and accept the theory. I was at Grammar School aged about 12 when the master opened up the debate without any ob<x>jections. No Einsteins just simple common sense.
Yes, I did know. The Science/Religion conflict is a relatively recent phenomenon and a product of the atheist movement.
You need to study the issue. The dispute was not over the science, but that Galileo had pronounced that the Bible may only be taken literally on matters of theology; his error was to presume that the Bible may not ever be taken literally on matters pertaining to the physical universe.
I do now! Thank you!
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The express lane is the linea rapida. Coke comes in glass bottles. Jalapeños are 99 cents a can and green chilies are on special up front for 79 cents a pound.
The Food City on Broadway Road near Country Club Drive in Mesa is a larger version of many grocery stores in Mexico. The chain has grown from its original Phoenix store acquired in 1993 to 62 stores in Arizona. And another is on the way, says Diana Bejarano-Medina, a spokeswoman for Bashas', which owns Food City and AJ's grocery stores.
"To me that speaks to the growth of the Hispanic population," she says. "We have in some neighborhoods chosen to even convert some stores to Food City when the neighborhood changes. We try to serve each of the neighborhoods neighborhood by neighborhood. If it needs an AJ's, we put in an AJ's, if it needs a Bashas', we put in a Bashas', if it needs a Food City, we put in a Food City."
Bashas' is the mainstream market, AJ's is the upscale version.
In Mesa, there are nine Bashas', five Food Citys and one AJ's.
Some of the products in Food City are specialty items from Mexico, Bejarano-Medina notes.
The songs heard overhead are in Spanish and there are fancy sombreros decorating the walls. The bakery, called the "panaderia," sells duros — fried pinwheel snacks. The deli offers menudo and chili verde, which can be washed down with guava nectar.
Eggs come in five-dozen cartons, there are several varieties of chilies, and beans and rice are sold in tubs the size of kids' plastic play pools. Hot sauce bottles sit on dining tables next to the deli. Chickens are being grilled out front.
Spanish is the spoken language, mostly, except when it comes to the intercom. "Mario to the deli," a manager calls out on a recent weekday.
Caroline Novak, manager of the Thrift Town thrift store next door to Food City, sends husbands to the deli for Mexican pastries while their wives shop.
At her store, the songs overhead are in English but the sale signs are bilingual. Thrift Town has been on the corner for four years and Novak has been there for three. About 80 percent of her customers are Hispanic, she says.
"We welcome the culture," says Novak, who was born and raised in Arizona and spent 14 years in Tucson. "They feel flattered when I speak their language."
She speaks enough Spanish that she's able to converse with a man who is looking for the key to the locked restroom. But sometimes her employees have to translate. Her job has forced her to become bilingual, Novak says.
She says many Hispanics purchase cut-rate shoes and clothes to resell them in Mexico.
Other customers include Japanese who are interested in Western wear and vintage clothes for resale in Japan.
While the store has always been busy, Novak says a recent advertising push has helped increase traffic.
"You've got the barrios right over there," she says motioning across Country Club. "That's what you see is Hispanic."
She said many of her Hispanic customers are surprised when they get to the United States.
"I think they get exploited," Novak says.
"A lot of them come over here thinking there's jobs and there's not that many jobs."


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Novemeber 17, 2010 will be the last day of broadcasting...
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This historic log home is located in downtown Pinedale, near restaurants and shopping. Most of the five rooms have private bathrooms and two have old-fashion fire places. There are plenty of family heirlooms, but all the bed mattresses are new. Every room has high-speed internet and cable TV.
Chambers House Bed & Breakfast
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H&S is strength at Stanford's core
In establishing Stanford University in 1891, Jane and Leland Stanford declared that this institution should educate "cultured and useful citizens." In the years since its creation, the university has grown into one of the world's premier centers of teaching and research.
Delivering a transformative education is the core mission of the School of Humanities & Sciences.
The School of Humanities and Sciences is the soul—the core—of a Stanford University education. It's one of the primary reasons students come to Stanford.
The goal of educating cultured and useful citizens remains as relevant today as it was 120 years ago. But the definition of such an education has dramatically changed. The world has changed; Stanford students have changed; and the education provided by the School of Humanities and Sciences has risen to meet the challenge.
In the Spotlight:
- Stanford Cantor Arts Center presents solo exhibition of Jacob Lawrence's work
- One of the largest collections of works by American artist Jacob Lawrence (1917–2000) in any museum belongs to the Cantor Arts Center, and is now on view to the public. Read More »
- Stanford's Ants in Space study launches citizen science for students worldwide
- Want to teach high school students about science, technology, engineering and math? "Get ants," advises Stanford biologist Deborah M. Gordon, who sent ants to the International Space Station in January 2014. Read More »
Latest NewsView all »
- Latin American authors reshaping world literature, Stanford literary scholar says
- May 21 - Stanford scholar Héctor Hoyos' research goes beyond famed writers to uncover a whole generation of Latin American authors who are contributing novel perspectives on the evolving landscape of global culture. Read more »
- TEDxStanford presenters describe turning points and opportunities
- May 18 - The fourth annual TEDxStanford conference was a rich experience for everyone. Read more »


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So, did anyone see something revealing that the recap missed? What was Stephen Amell talking about in his tweet?
Completely agree with you - this episode felt completely luke-warm.
In our review, we get a little ranty about how clearly telegraphed everything is: there's nothing that isn't completely obvious or "oh so perfectly" slotted in. The show can do a lot better than these kind of throw away episodes where we don't learn anything about the characters.
Hopefully Seth Gabel coming on next week will do the trick.
Absolutely! I don't get what the big deal about this episode was. The tweets are becoming over glorified 140 character puffs of caricature. Don't see what the holy s$@# balls was all about. @Stephen: I watched it...again.
I think the the entire populace has finally caught on to the equation....The more they hype, the worse it is!
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text:
Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes
- Z. Asghar,
- D. Yau,
- F. Chan,
- D. LeRoith,
- C. B. Chan,
- M. B. Wheeler
- … show all 6 hide
Although insulin resistance induces compensatory increases in beta cell mass and function to maintain normoglycaemia, it is not clear whether insulin resistance can precipitate beta cell dysfunction and hyperglycaemia without a pre-existing beta cell susceptibility. We therefore examined the beta cell phenotype in the MKR mouse, a model in which expression of a dominant-negative IGF 1 receptor (IGF1R) in skeletal muscle leads to systemic insulin resistance and diabetes.
Materials and methods
Circulating glucose, insulin and glucagon concentrations were measured. Insulin sensitivity, glucose tolerance and insulin release in vivo were assessed by i.p. insulin and glucose tolerance tests. Beta cell function was assessed via insulin secretion from isolated islets and the glucose gradient in the perfused pancreas. Beta cell morphology was examined via immunohistochemistry. MKR mice were fed a high-fat diet containing sucrose (HFSD) to test metabolic capacity and beta cell function.
Insulin-resistant MKR mice developed hyperglycaemia and a loss of insulin responsiveness in vivo. Basal insulin secretion from the perfused pancreas was elevated, with no response to glucose. Despite the demand on insulin secretion, MKR mice had increased pancreatic insulin content and beta cell mass mediated through hyperplasia and hypertrophy. The HFSD worsened hyperglycaemia in MKR mice but, despite increased food intake in these mice, failed to induce the obesity observed in wild-type mice.
Our studies demonstrate that insulin resistance of sufficient severity can impair glucose-stimulated insulin secretion, thereby undermining beta cell compensation and leading to hyperglycaemia. Moreover, because insulin stores were intact, the secretory defects reflect an early stage of beta cell dysfunction.
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- Kubota, N, Tobe, K, Terauchi, Y (2000) Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia. Diabetes 49: pp. 1880-1889 CrossRef
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- Kahn, SE (2001) Clinical review 135: the importance of beta-cell failure in the development and progression of type 2 diabetes. J Clin Endocrinol Metab 86: pp. 4047-4058 CrossRef
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- Bruning, JC, Gautam, D, Burks, DJ (2000) Role of brain insulin receptor in control of body weight and reproduction. Science 289: pp. 2122-2125 CrossRef
- Michael, MD, Kulkarni, RN, Postic, C (2000) Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Mol Cell 6: pp. 87-97 CrossRef
- Bluher, M, Michael, MD, Peroni, OD (2002) Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. Dev Cell 3: pp. 25-38 CrossRef
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- Wang, X, Li, H, Leo, D (2004) Gene and protein kinase expression profiling of reactive oxygen species-associated lipotoxicity in the pancreatic beta-cell line MIN6. Diabetes 53: pp. 129-140 CrossRef
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- Roduit, R, Masiello, P, Wang, SP, Li, H, Mitchell, GA, Prentki, M (2001) A role for hormone-sensitive lipase in glucose-stimulated insulin secretion: a study in hormone-sensitive lipase-deficient mice. Diabetes 50: pp. 1970-1975 CrossRef
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- Joseph, JW, Kalitsky, J, St Pierre, S, Brubaker, PL (2000) Oral delivery of glucagon-like peptide-1 in a modified polymer preparation normalizes basal glycaemia in diabetic db/db mice. Diabetologia 43: pp. 1319-1328 CrossRef
- Zhao, H, Yakar, S, Gavrilova, O (2004) Phloridzin improves hyperglycemia but not hepatic insulin resistance in a transgenic mouse model of type 2 diabetes. Diabetes 53: pp. 2901-2909 CrossRef
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- Chua, S, Liu, SM, Li, Q, Yang, L, Thassanapaff, VT, Fisher, P (2002) Differential beta cell responses to hyperglycaemia and insulin resistance in two novel congenic strains of diabetes (FVB-Lepr (db)) and obese (DBA-Lep (ob)) mice. Diabetologia 45: pp. 976-990 CrossRef
- Laybutt, DR, Weir, GC, Kaneto, H (2002) Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes. Diabetes 51: pp. 1793-1804 CrossRef
- Jonas, JC, Sharma, A, Hasenkamp, W (1999) Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes. J Biol Chem 274: pp. 14112-14121 CrossRef
- Laybutt, DR, Glandt, M, Xu, G (2003) Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes. J Biol Chem 278: pp. 2997-3005 CrossRef
- Ruderman, N, Prentki, M (2004) AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome. Nat Rev Drug Discov 3: pp. 340-351 CrossRef
- Prentki, M, Joly, E, Assaad, W, Roduit, R (2002) Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. Diabetes 51: pp. S405-S413 CrossRef
- Kulkarni, RN, Bruning, JC, Winnay, JN, Postic, C, Magnuson, MA, Kahn, CR (1999) Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 96: pp. 329-339 CrossRef
- Kulkarni, RN, Winnay, JN, Daniels, M (1999) Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines. J Clin Invest 104: pp. R69-R75
- Leibiger, IB, Leibiger, B, Berggren, PO (2002) Insulin feedback action on pancreatic beta-cell function. FEBS Lett 532: pp. 1-6 CrossRef
- Title
- Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes
- Journal
Volume 49, Issue 1 , pp 90-99
- Cover Date
- 2006-01-01
- 10.1007/s00125-005-0045-y
- Print ISSN
- Online ISSN
- 1432-0428
- Publisher
- Springer-Verlag
- Additional Links
- Topics
- Keywords
- Beta cell compensation
- Beta cell dysfunction
- Insulin resistance
- Insulin secretion
- Industry Sectors
- Authors
- Z. Asghar (2)
- D. Yau (2)
- F. Chan (2)
- D. LeRoith (3)
- C. B. Chan (4)
- M. B. Wheeler (1) (2)
- Author Affiliations
- 2. Department of Physiology, University of Toronto, 1 King's College Circle Room 3352, Toronto, ON, Canada, M5S 1A8
- 3. Diabetes Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD, USA
- 4. Department of Biomedical Sciences, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE, Canada
- 1. Department of Medicine, University of Toronto, Toronto, ON, Canada


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Cheap SHH to Brunswick flights
Popular Flights from Shishmaref, Alaska
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Route information for flights from Shishmaref AK to Golden Isles.
4,112.30 miles
BQK - Golden Isles Airlines
Browse the most popular airlines servicing the Brunswick (BQK) airport. Visit their flights pages to learn more about the most popular routes these carriers fly.


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NEW YORK (TheStreet) -- Shares of Dean Foods Co. (DF - Get Report) are down -1.96% to $17.04 on heavy volume trading after a U.S. insider trading investigation of Carl Icahn's (IEP - Get Report) attempt to buy The Clorox Co. (CLX - Get Report) in 2011 has been hampered by reports tying it and trades in Dean Foods to golfer Phil Mickelson and sports gambler William Walters, sources told Bloomberg.
Investigators are reviewing large option trades ahead of Icahn's $10.2 billion offer for Clorox, as well as trading by Mickelson and Walters in Dean Foods in 2012, the source said.
None of the three individuals has been accused of any wrongdoing.
Must Read: Warren Buffett's 25 Favorite Growth Stocks
- Despite its growing revenue, the company underperformed as compared with the industry average of 3.3%. Since the same quarter one year prior, revenues slightly increased by 2.1%. Growth in the company's revenue appears to have helped boost the earnings per share.
- The company's current return on equity greatly increased when compared to its ROE from the same quarter one year prior. This is a signal of significant strength within the corporation. Compared to other companies in the Food Products industry and the overall market, DEAN FOODS CO's return on equity significantly exceeds that of both the industry average and the S&P 500.
- DEAN FOODS CO reported significant earnings per share improvement in the most recent quarter compared to the same quarter a year ago. The company has demonstrated a pattern of positive earnings per share growth over the past year. However, we anticipate underperformance relative to this pattern in the coming year. During the past fiscal year, DEAN FOODS CO increased its bottom line by earning $3.39 versus $0.26 in the prior year. For the next year, the market is expecting a contraction of 83.2% in earnings ($0.57 versus $3.39).
- The gross profit margin for DEAN FOODS CO is rather low; currently it is at 19.46%. It has decreased from the same quarter the previous year. Along with this, the net profit margin of -0.38% trails that of the industry average.
- The company, on the basis of change in net income from the same quarter one year ago, has significantly underperformed when compared to that of the S&P 500 and the Food Products industry. The net income has significantly decreased by 101.8% when compared to the same quarter one year ago, falling from $492.61 million to -$8.96 million.
- You can view the full analysis from the report here: DF Ratings Report


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Starting with 2,942 genes that TCGA identified as overexpressed in the mesenchymal group, they narrowed that list to 253 genes, 219 of which were associated with miRNA.
They found that the 219 miRNA-associated mesenchymal genes divided 455 ovarian cancer patients into two clusters:
The team confirmed these results in three independent data sets totaling 560 ovarian cancer patients.
Nineteen miRNAs were identified, eight of which were predicted to control 89 percent of the 219 miRNA-associated genes. Of the eight, the least was known about miR-506, and it was least expressed in the mesencyhmal cases. "We decided to focus on miR-506," Zhang said.
miR-506 blocks mesenchymal, helps epithelial proteins
In a series of cell line experiments, the scientists forced overexpression of miR-506 and a control miRNA in ovarian cancer cells. Treated cells had much lower levels of two important mesenchymal markers and higher levels of E-cadherin, a protein vital to epithelial cells.
Additional experiments showed miR-506 specifically inhibited SNAI2, a mesenchymal-cell-promoting protein, by binding to the promoter region of its gene, blocking activation.
Transforming growth factor beta (TGF) induces epithelial-to-mesenchymal cell transition, and the team found that it was prominent in the mesenchymal type of ovarian cancer. In cancer cells treated with miR-506 and then treated with TGF, the miRNA completely abolished TGF's effects.
In human tumors, more miR-506 tied to improved survival
Analysis of 92 ovarian cancer tumors from Tianjin Hospital in Tianjin, China, showed:
|Contact: Scott Merville
University of Texas M. D. Anderson Cancer Center


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Book your room at Hampton Inn Florence Midtown
One King and One Sofa Bed, SmokingMax Occupancy: 4 guests (up to 3 children, 3 infants)
One king study sofabed non smokeMax Occupancy: 4 guests (up to 3 children, 3 infants)
Two Queen Beds, AccessibleMax Occupancy: 4 guests (up to 3 children, 3 infants)
Room, 2 Queen Beds, Smoking, RefrigeratorMax Occupancy: 4 guests (up to 3 children, 3 infants)
Two Queens Microwave Fridge SmokingMax Occupancy: 4 guests (up to 3 children, 3 infants)
Deluxe, One King Bed, with Jetted TubMax Occupancy: 4 guests (up to 3 children, 3 infants)
Hotel in Florence with free breakfast and outdoor pool
Collect 200 points
Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.*Offers may apply
Located in the heart of Florence, this hotel is within 2 mi (3 km) of Regency Square Mall, Children's Museum of the Shoals, and Shoals Conference Center. Renaissance Tower and Kennedy-Douglass Center for the Arts are also within 3 mi (5 km).
Hotel Features
An outdoor pool, a fitness center, and a bar/lounge are available at this smoke-free hotel. Free buffet breakfast and free self parking are also provided. Additionally, a business center, conference rooms, and express check-out are onsite.
Room Amenities
All 90 rooms provide conveniences like refrigerators and microwaves, plus free WiFi and flat-screen TVs. Guests will also find coffee makers, hair dryers, and phones.Information missing or incorrect? Tell us!
Hotel Amenities
Hotel Amenities
Hampton Inn Florence Midtown features an outdoor pool and a fitness center. A bar/lounge is on site where guests can unwind with a drink. A complimentary breakfast is offered.
This hotel offers access to a business center. This business-friendly hotel also offers express check-out and a safe deposit box at the front desk. Onsite self parking is complimentary.
Hampton Inn Florence Midtown is a smoke-free property.
- Conference space
- Total number of rooms - 90
- Outdoor pool
- Fitness facilities
- Number of floors - 4
- Free breakfast
- Bar/lounge
- Business center
- Express check-out
- Safe-deposit box at front desk
- Free self parking
- Smoke-free property
Family Friendly Amenities
- Outdoor pool
- Free Wi-Fi
- Refrigerator
- Microwave
Available in all rooms: Free WiFi
Free self parking
Room Amenities
- Phone
- Refrigerator
- Coffee/tea maker
- Microwave
- Hair dryer
- Iron/ironing board
- Desk
- Flat-panel TV
- Free WiFi
Where to Eat
Guests are offered a complimentary hot/cold buffet breakfast.
Nearby Things to Do
Recreational amenities at the hotel include an outdoor pool and a fitness center.
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
- In-room accessibility
Hotel Policies
Payment types
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.


text:
View Poll Results: Favorite combos?
- Voters
- 40. You may not vote on this poll
Multiple Choice Poll.
Results 6 to 10 of 11
Thread: Which combo?
July 16th, 2013 02:19 PM #6
July 16th, 2013 03:20 PM #8
Fiona Carys is beautiful! It feels really spunky and different while still being feminine and sweet. I absolutely love Carys in the middle! I also like Gwyneth but I feel it doesn't flow right with Carissa and Josephine or maybe its that the styles are so different I'm not certain. What about Gwyneth Carys?23 year old name lover with a passion for art history married for three years to my much better half
talking with said partner about trying to conceive our first late this year
July 16th, 2013 04:40 PM #10
July 16th, 2013 11:08 PM #12frontrunners:
Jane Cosima | Quentin Cyrus
Alice | Naomi | Lucy | Fiona | Faye
Rosalind | Bridget | Evangeline | Gwyneth | Delilah
Jude | Asher | Griffin | Nathan | Oliver
Lars | Bram | Oren | Kieran | Rhett
Carly Beth
| married 5.17.14 |
| ttc March 2016 |
July 16th, 2013 11:25 PM #14
I voted Fiona Carys which is lovely, but had Evangeline Carys been an option it would have definitely gotten my vote.
♥ Clara Dean Lucy Dominic ♡
Feel free to ask me anything about saints names


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Strong Talks Merging "Super-Cute" with "Super-Psycho" for "Arkham Knight's" Harley Quinn
Video Games, Comic Books, TV, Film
Every day this year, I will be examining the first pages of random comics. Today's page is from X-Men Unlimited #16, which was published by Marvel and is cover dated September 1997. Enjoy!
Continue Reading »
Comics Should Be Good accepts review copies. Anything sent to us will (for better or for worse) end up reviewed on the blog. See where to send the review copies.


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Neurons in the cortical area 5 are active when a cat is straddling an obstacle.
This animation series shows four experiments that compare the activity patterns of a wild-type fly keeping a normal schedule with those of a mutant fly apparently following a 19-hour internal clock.
Demonstrates how changes in the amount of fat tissue lead to changes in leptin levels and thus changes in appetite.
A touch to the Aplysia's siphon causes a gill withdrawal, a simple reflex for studying memory.
The bobtail squid swims during the night to hunt. During the day, it burrows to hide from predators.
Even when distracted by food, the cat's brain encodes and retains the location of an obstacle.
Video microscopy of mating between a male and a hermaphrodite C. elegans roundworm.
Dr. Jessell's leg muscle activation patterns are recorded during walking.
This species of cone snail immobilizes its prey in a split second with lightning-strike cabal toxins.
A fish-hunting cone snail strikes its prey with a venomous harpoon, causes paralysis, and eats it.
Larger cone snails produce more venom and are more dangerous to human beings in an accidental stinging.
A worm-hunting cone snail species feeds on fireworms, and is unaffected by the prey's sharp bristles.
A species of fish-hunting cone snail quickly immobilizes its prey and swallows it.
Fossilized dung beetle balls are part of a comprehensive fossil collection project to reconstruct the habitat of Ardipithecus ramidus.
Male courtship dances in two fruit fly species show that the wing spots play a prominent role.
Chimpanzees are capable of using rocks as tools to crack nuts for eating. But they don't appear to use sharp-edged tools.
Mice can be trained to use spatial cues to navigate a maze that tests their ability to remember specific locations.
Dr. Evans compares the activity of a normal mouse to one with a mutation in a key gene controlling obesity.
To prevent mosquitoes from spreading diseases, it's essential to understand their life cycle.
Dr. Ronald Evans discusses the so-called "marathon" mouse, with a mutation in the PPAR-gamma gene, and its performance on a treadmill relative to a normal mouse.
At the end of the ice age, the retreating ice sheet created many new lakes, some of which were colonized by sticklebacks.
This time-lapse videoclip shows human circadian activity while assembling a T. rex skeleton.
This time-lapse videoclip illustrates a mouse's nocturnal behavior.
Dr. Jason Biggs of the University of Guam Marine Laboratory discusses the anatomy of cone snails and introduces us to a variety of cone snail species with different tactics to hunt and capture their prey.
Dr. Harshad Vishwasrao guides you through a collection of images showing neuronal growth and synaptic formation representative of anatomical changes that occur during learning.
Venomous carniverous cone snails are a rich source of molecules for scientific research and potential drug development.
In this ten-minute Q&A session, Dr. Olivera answers questions on cone snail behavior, venoms, and biodiversity.
What is mind? Can molecular biology help us understand mental function?
The history of localization of function in the brain, and research that led to the understanding of localization of memory.
Understanding the neural circuits in the spinal cord that control movement.
The cellular and molecular nature of learning and memory, investigated in simpler sea slugs and more-complex mice.
In the 2004 Holiday Lectures on Science, HHMI investigators Ronald M. Evans and Jeffrey M. Friedman discuss how the body regulates weight by carefully controlling the storage and burning of fat—and how a better understanding of these complex metabolic systems could lead researchers to treatments...
Dr. Friedman introduces the genes and circuits that control appetite, including the key role of leptin.
Dr. Evans describes how fat communicates with muscle and how diet and exercise influence that relationship.
Four lectures highlight the research of two scientists who have made groundbreaking discoveries elucidating the molecular basis of circadian clocks—the internal timekeepers that govern fluctuations in behavior and physiology on a 24-hour cycle.
Dr. Joseph Takahashi takes us on an exciting journey into a very special region of the brain—the biological clock that governs our physiology and certain behaviors.
Although tiny in size, the fruit fly has had a major impact on our understanding of circadian rhythms.
This survey, developed by Horne and Ostberg, will let you determine if you are a morning or an evening person.
Explore the biology of the symbiotic relationship between the Hawaiian Bobtail squid and bioluminescent bacteria Vibrio fischeri.
Different gaits employed by animals and how the nervous system is able to switch between them.
To accompany the lecture series Viral Outbreak: The Science of Emerging Disease.
To accompany the lecture series AIDS: Evolution of an Epidemic. In this activity, you simulate taking HIV antiretroviral drugs by using tic tac mints and Kool-Aid packets.
This activity uses the planaria's property for regeneration and compares how long it takes for planaria cut in different places to regenerate a head.
In this activity, students rear mosquitoes in chambers and test variables that might affect the life cycle of the mosquito.
Four decades of research on finch species that live only on the Galápagos Islands illuminate how species form and multiply.
In the Caribbean islands, adaptation to several common habitats has led to a large adaptive radiation with interesting examples of convergent evolution.
The richness and diversity of life raises two of the most profound questions in biology: How do new species form? And, why are there so many species?
Finches discriminate between members of their own species and those of a closely related species based on song and appearance.
The following classroom-ready resources complement The Origin of Species: The Beak of the Finch. By following four decades of research on the finches of the Galápagos islands, the film illustrates how geography and ecology can drive the evolution of new species.
The following classroom-ready resources complement The Origin of Species: Lizards in an Evolutionary Tree. Research on the anole lizards is enriching our understanding of evolutionary processes, such as adaptation by natural selection, convergent evolution, and the formation of new...
This animation features the anole lizards as an example of how a single species can split and multiply into many different species with distinct traits.
Dr. Elinor Karlsson discusses her work with dogs as a model organism for genomic studies.
The fins of the scalyhead sculpin are related to our arms.
This classroom experiment supports the film The Origin of Species: The Beak of the Finch. Students collect and analyze data to learn why even slight variations in beak size can make the difference between life and death.
The shape of our hands comes from tree-dwelling ancestors.
Female peacock spiders stay with their young in an egg sac until they can fend for themselves.
Infant lemurs hitch a ride through the forest by holding on to their mother's tummy or riding piggyback.
The male peacock spider performs a spectacular dance to attract a mate—but the female is not always impressed.
The Lizard Evolution Virtual Lab was developed by a team of scientists, educators, graphic artists, and film makers to explore the evolution of the anole lizards in the Caribbean.
Weaver ants labor to carry a live land snail back to their nest in Gorongosa National Park.
HHMI investigator Jeff Friedman provides an update to his 2004 lectures on obesity.
Tracking the flight paths and speeds of fruit flies in a wind tunnel may help design better flying robots.
The Lizard Evolution Virtual Lab app lets you explore the evolution of the anole lizards in the Caribbean on your iOS device.
The Plymouth anole (Anolis lividus) lizard is found only on the Caribbean island of Montserrat—and it is the only anole species living there.
Ecosystems in the world-famous national park are threatened by warming temperatures.
This activity supports the film The Origin of Species: Lizards in an Evolutionary Tree. Students are guided to sort the lizard species by appearance, then generate a phylogenetic tree using the lizards' DNA sequences to evaluate whether species that appear similar are closely related to...
The flight patterns of a flock of black vultures are revealed by a novel digital video technique.
Dr. Zoghbi introduces the topic of Rett syndrome by showing how development usually progresses in a young girl. She then shows an excerpt from ...
A close-up view of the sound-producing structure on the wing of a field cricket (Gryllus pennsylvanicus).
Warthog mothers look after their young in small family groups.
A smalltooth sawfish (Pristis pectinata) patrols the murky waters of the Everglades National Park in Florida.
Leaf-cutter ants practice fungus agriculture to provide the ant colony with a steady source of food.
Animal mimics evolved markings that make them look either like other animals or inanimate objects.


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Justice For Trayvon: 10 Burning Questions About The George Zimmerman Murder Trial- By Bossip Staff Categories: Arrests, Bolitics, Entertainment
This has been the most stressful, intriguing and heartbreaking trial in recent memory with incredibly-petty defense attorneys, cunning prosecutors fighting for justice and a fat-faced blob (defendant George Zimmerman) with the most punchable face ever. Must watch TV? Absolutely, with several key moments that inspired the following questions.
Here are ten burning questions about the George Zimmerman Murder trial. Take a look.


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A recent decision of the Supreme Court of Canada has held that a court may properly dismiss an action arising from an international commercial agreement, even after the defendant has filed a Statement of Defence. This decision is important since the contracts in issue contained both a forum selection clause and an arbitration clause, and the consequence of the filing of the Statement of Defence is not the same for each of those clauses.
In holding that the action could be dismissed after the filing of a Statement of Defence, the Supreme Court effectively applied the law applicable to forum selection clauses, not the law applicable to international commercial arbitrations.
arbitration-international commercial arbitration-stay motion-alleged waiver of arbitration agreement
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Antigone, Chronia Polla! I wish for you many years of good health, full of Peace, Light and Happiness!
Antigone, Ithaca is symbolic of our life.Please click on the link below to my spirituality blog for more on this beautiful poem. ~~~ ITHACA~~~A SPIRITUAL POEM ON LIFE~~~
Please sign this very important Petition concerning Gross Human Rights Abuse in America!
Here is the link to my Petition - (Visit my page & share with others)
- Sheldon


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In an age where accurate time measurement is taken for granted, the upcoming auction of an 1825 marine chronometer highlights just how far science has advanced in the last 200 years. The marine chronometer was a critical technology enabling navigation at sea. This 190 year-old example, which is heading for the auction block on July 9, has certainly witnessed its fair share of history in fulfilling that critical scientific role, having accompanied Charles Darwin on his epic five-year second voyage (1831-1836) to South America and the Galapagos Islands, the North American Boundary Expedition (1843-1846) which established the border between the USA and Canada and the 1857 survey of the Australian coastline which saw the naming of Darwin and the Fitzroy River. Given its stellar provenance, the chronometer seems ridiculously cheap if it does fall within its expected price range of … £30,000-50,000. Read More
Following the tsunami that hit Japan in March, 2011, designer Chris Robinson was inspired to create an escape pod to ensure he and his family could survive if such a disaster were to occur in his home city of Palo Alto, California. After some two years of painstaking design and construction, his floating off-grid shelter, dubbed Tsunamiball, is nearing completion. Read More
It becomes difficult for boats to stand out when they're stuffed into an expo center segmented into row after row of seafaring vessels and marine hardware. Even massive yachts and striking boat concepts can start to look alike after a few passes through a boat show. One boat that did grab our attention at the Boot Dusseldorf show earlier this year is the new Frauscher 858 Fantom, a V8-powered craft inspired by German and Italian sports cars. Read More
Horatio Hornblower meets Jean-Luc Picard on the ship's bridge of 2025 as Finnish applied research organization VTT and Rolls-Royce present their vision of seafaring ten years from now. Presented in 3D animation videos that projects current technology to the near future, the study shows a world where ship captains call on heads-up displays and high-tech workstations turn the bridge into an augmented reality command and control system. Read More
New toys for land and sea in 2014
March 11, 2014
In January, Gizmag traveled around Germany to the Boot Dusseldorf and ISPO Munich shows to take a look at the latest in everything from monolithic yachts to tiny sports sensors. We've already covered many of our finds, but both shows were so filled with new gear and innovation, we've combined some of the remaining ones into one big gallery. Here is some of the latest, most interesting hardware for enjoying water and land. Read More
GE using medical X-rays to inspect undersea pipelines
February 26, 2014
Using X-rays and other forms of radiation has been a standard tool for testing pipelines for decades, but until now it's been largely confined to factories and land-based pipelines instead of the deep seabed. That's changing as GE adapts its medical X-ray systems to work in the crushing pressures of the deep oceans, as part of a remote-controlled submersible rig for examining pipelines in place. Read More
At last month's Boot Dusseldorf show, we learned two things about electric boats. One, there aren't that many of them, and two, those that are available tend to be on the small side – as evidenced by day cruisers like the Joyboat and Superiore Uno. The latter point was true save for one exception: the 23-foot (6.9 m) long Energy 23cs from Slovenia's Alfastreet Marine. The 23cs is an (optionally) electric boat with sleeping quarters, plus a few other tricks up its sleeve. Read More
X-Jetpacks tweaks the ride of the hydro jetpack
February 11, 2014
Water-based jetpacking originally looked like an insane activity for the extremely rich and bored, but it has gradually gained in popularity. First, we saw the JetLev-Flyer, then the Flyboard, and now the X-Jetpack H3X Hydro. More than just a "me too" competitor in the water jetpack market, the H3X offers a few key evolutionary advantages for novices, families and daredevils alike. Read More
Seaway debuts flagship Greenline 48 hybrid yacht
January 29, 2014
A motor yacht's nice, big diesel engines are wonderful if you're in a hurry, but they're thirsty, not very green, and not the best of neighbors as they roar away while leaving harbor at first light. As a quieter, cleaner alternative for the luxury boating market, Greenline Boat's Greenline 48 Hybrid motor yacht made its world première last week at the Dusseldorf Boat Show. Using hybrid electric technology combined with solar panels and a new hull design for greater efficiency, Greenline sees is as a the flagship of the company's range and a bridge between its Greenline line and its transoceanic OceanClass yachts. Read More
The National Science Foundation (NSF) announced on Friday that the Alvin deep-sea submersible is returning to service. The DC3 of the oceanographic world was launched fifty years ago in 1964 and is ready to begin its second half-century of service after a three-year overhaul involving significant redesigns and upgrades. Read More