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|Table of Contents
|Vol. 114, No. 1, 2006
Issue release date: May 2006
|Section title: Original Article
SLUG (SNAI2) overexpression in embryonic developmentPérez-Mancera P.A.a · González-Herrero I.a · Maclean K.e · Turner A.M.e, f · Yip M.-Y.g · Sánchez-Martín M.a · García J.L.b · Robledo C.b · Flores T.c · Gutiérrez-Adán A.d · Pintado B.d · Sánchez-García I.a
aLaboratorio 13 and b Laboratorio 12, Instituto de Biología Molecular y Celular del Cáncer (IBMCC), CSIC/Universidad de Salamanca, cServicio de Anatomía Patológica, Universidad de Salamanca, Salamanca; dArea de Reproducción Animal, Centro de Investigación y Tecnología, Madrid (Spain); eDepartment of Medical Genetics, Sydney Children's Hospital, and fSchool of Women's and Children's Health, University of New South Wales; gMolecular & Cytogenetics Unit, Prince of Wales Hospital, Sydney (Australia)
Published online: 5/24/2006
Issue release date: May 2006
Number of Print Pages: 6
Number of Figures: 6
Number of Tables: 0
ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)
For additional information: http://www.karger.com/CGR
The Snail-related zinc-finger transcription factor, SLUG (SNAI2), is critical for the normal development of neural crest-derived cells and loss-of-function SLUG mutations have been proven to cause piebaldism and Waardenburg syndrome type 2 in a dose-dependent fashion. However, little is known about the consequences of SLUG overexpression in embryonic development. We report SLUG duplication in a child with a unique de novo 8q11.2→q13.3 duplication associated with tetralogy of Fallot, submucous cleft palate, renal anomalies, hypotonia and developmental delay. To investigate the effects of Slug overexpression on development, we analyzed mice carrying a Slug transgene. These mice were morphologically normal at birth, inferring that Slug overexpression is not sufficient to cause overt morphogenetic defects. In the adult mice, there was a 20% incidence of sudden death, cardiomegaly and cardiac failure associated with incipient mesenchymal tumorigenesis. These findings, while not directly implicating Slug in congenital and acquired heart disease, raise the possibility that Slug overexpression may contribute to specific cardiac phenotypes and cancer development.
© 2006 S. Karger AG, Basel
Request reprints from Isidro Sánchez-García
Laboratorio 13, Instituto de Biología Molecular y
Celular del Cáncer (IBMCC), CSIC/Universidad de Salamanca
Campus Unamuno, ES–37007 Salamanca (Spain)
telephone: +34-923-238403; fax: +34-923-294813; e-mail: firstname.lastname@example.com
P.A.P.-M., I.G.-H., and K.M. contributed equally to this work.
Supported by MEyC (BIO2000-0453-P4-02, SAF2003-01103, FIT-010000-2004-157, and PETRI N° 95-0913.OP), Junta de Castilla y León (CSI03A05), ADE de Castilla y León (04/04/SA/0001), FIS (PI020138, G03/179, and G03/136), Fundación de Investigación MMA and USAL-CIBASA project. M.S.-M. is supported by Fundación Científica de la AECC. K.M. is a recipient of an Australian National Health and Medical Research scholarship.
Manuscript received: 22 August 2005
Accepted in revised form for publication by B.H.F. Weber,: 30 September 2005.
Number of Print Pages : 6
Number of Figures : 6, Number of Tables : 0, Number of References : 23
Cytogenetic and Genome Research
Vol. 114, No. 1, Year 2006 (Cover Date: May 2006)
Journal Editor: Schmid, M. (Würzburg)
ISSN: 1424–8581 (print), 1424–859X (Online)
For additional information: http://www.karger.com/CGR
Published online: 5/24/2006
Issue release date: May 2006
Number of Print Pages: 6
Number of Figures: 6
Number of Tables: 0
ISSN: 1424-8581 (Print)
eISSN: 1424-859X (Online)
For additional information: http://www.karger.com/CGR


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The Spanish-style Carnell Building, considered an important part of the downtown architectural fabric for almost 80 years, is getting a second chance.
The second story caught fire a year ago this month, and ever since, the building has sat behind a tall green fence with only a portion of the second floor visible from the street. Its walls, clay-tiled roof and ornamental details are gone.
PHOTOS: Carnell Building burns in Palm Springs ...

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These celebs showed you can give the cleavage-baring tops a day off and still look h-o-t. More
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Do you just love hanging out googling what the cast of Game of Thrones looks like in real life?
The correct answer is "who doesn't!?" More


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Apparently that happens on Radeon card
I really enjoyed the demo on PS3. I've got too many games for this to be a first day buy. But I dont think any game for me anymore is first day since everything typically gets some DLC that is included 6 months from release and less than 30 bucks.
A chest in the first town my might and rogue builds got a shocking dagger while my mage build got a septre. This was nice, if the game actually takes into account your build.
The demo had alot of graphic bugs. I got a nice bug where all the dialog text flashed by and there wasnt any actor speech. It was nice since it was on my 2nd play through.
I hadn't heard about this either until I saw an article that you get free dlc for ME3 by playing the demo... That's all it took to get me to DL the game... It reminded me of WoW too... just the look and has that same sort of cartoony aspect to it. I ended up enjoying the game so I went and preordered it... I probably won't get to finish it until after I finish ME3 though...
I Don't Know I'm Still Thinking! -> ->
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Last edited by appleyum; 01-31-2012 at 02:19 PM..
So I played the demo. It seems... ok. I don't think I would pay full price on it. Maybe when it hits a steam sale.
Also, I am pretty sure not having threads of fate means your dude is a psychopath. I mean those killing animations are far beyond any sort of thing a soldier would do. You actually make a spike, pick up a guy and drag him to it, then proceed to impale him on it. It's very... off-putting compared to the theme otherwise in the demo. I wonder if it gets darker as it goes on? Anyhow I am pretty sure the fate mode thing is your character having a break with reality and then torturing people. It's very surreal.
those of you looking to pre-order, the PS3/360 versions are $45 shipped with UPS 3 Day at Newegg.
You got a question about Kohl's? Ask me or stop by the Official Kohl's & More thread! :: my first true FP deal
I have never preordered a game for the ol' PS3 before. How does the bonus content work? Do I have to unlock it somehow? Sorry if this is a stupid question, but I am kicking around preordering this from Amazon. Thanks in advance,
No one cares that you saved an extra nickel on this same deal back in 2007. If it doesn't apply to the current deal, please keep it to yourself.
Some items may require you to go through small part of the game before you get them, while others might just be in the inventory when you start the game.
Last edited by appleyum; 02-01-2012 at 08:56 AM..
If you prefer more
Action = Amalur
Open World = Skyrim
I don't read reviews any more. They tend to give 10s to games I hate and lower scores to games I can't stop playing. I rely on demos, gameplay vids, and this message board to help me figure out what to buy.
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Pet gift ideas this holiday
Pet Qwerks
Babble Balls
Find it at Petco and Bed Bath & Beyond
$9.99 -- $11.99
Find it at Petco and Bed Bath & Beyond
It's a ball with the gift of gab.
This is an interactive toy made by Pet Qwerks that talks when touched. It then shuts itself off when your pet is done playing.
There are Babble Balls made specifically for dogs, cats, birds, and ferrets. Choose from the wisecracking "Talking" balls or "Animal Sounds" balls.


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Today was the first day of the 2011 Pismo Beach KiteXpo and the conditions delivered on the Central Coast. This morning started with clear blue skies and riders were on the water by 1pm.Read More »
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Over 45 kiteboarders & competitors sailed through the Flying Under Canopies & Kites event. Lyle Partnered with Neil Hutchinson from SlingShot Kites bringing in some hot shot kiteboarders who have recently taken up the sport of skydiving. And the event attracted some of the best in both sports.Read More »
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Windance and Ocean Rodeo Weekend Demo/Beach Party: Hood River, May 29/30
If you're in or near Hood River, Oregon, the weekend of May 29, be sure to check out the free demos and beach party Saturday night hosted by Windance and Ocean Rodeo. Beside providing excellent service and products, they're a ...Read More »
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It will be one of those rare occasions when cricket will be on the back burner, and names of Ronaldo, Rooney and Ribery will be renting the air playing for their respective countries. Predictably, sports bars will be flooded with customers sporting jerseys of Spain, Brazil, Argentina — the Indian jersey will be put to wash — and house parties will have football for company. Indeed, India will become a part of the carnival.
In a country where — forgive the cliché — cricket is religion, football is vying for its share of sport-divinity, especially among the youth.
The growth of television has meant that every league across the world, from the English Premier League (EPL) to the UEFA Champions League to the Spanish league (La Liga), is televised live and marketed on par with cricket. In turn, these leagues rake in money through television rights for enabling Indians to watch their favourite stars play almost every week. Sounds perfect, doesn't it?
But it isn't. A couple of questions come up. First, how much do these leagues re-invest, or do something for the growth of the sport in India? For example, clubs like Manchester United, Manchester City, Liverpool, Inter Milan, Paris Saint-Germain and Bayern Munich have their own schools in India, where they frequently hold camps for kids. Some of these, like Manchester United and Bayern Munich, even train Indian talent at their respective clubs for a short period of time, ranging from a week to a fortnight. But it stops there.
Second, and more importantly, where does Indian football stand in the game that many believe will overtake cricket in the years to come in the country?
The first question was answered recently by the former deputy secretary general of FIFA, Jerome Champagne, who is running for the game's governing body's presidential elections in 2015. "EPL makes $50 million from India. How much do they re-invest in India? Zero," he said during his visit to India in March this year.
The second issue requires more than just number crunching. For too long, India has been considered as the 'sleeping giant' of world football. If that's true, it's been slumbering for too long.
The Indian national team is ranked 147th in the world. Just to give you a perspective on where India stands, here's a list of some countries ranked above us: Saudi Arabia (75), Uzbekistan (53), Qatar (95), China (96), Iraq (100), Kazakhstan (118), Tajikistan (121), Afghanistan (128), Thailand (143). FYR Macedonia, a country located in the central Balkan peninsula in southeast Europe that got its independence in 1991, is ranked 80. Sleeping giant who?
"I think you were not a sleeping giant always," Champagne said. "So you have to wonder why that happened. When Sepp Blatter (FIFA president) came here in April 2007, we launched a programme in India — 'Win in India With India' — and $8 million were allocated then. It's 2014 and there's still some money that has not been allocated. You should wonder why. Your country has very intelligent, educated people, strong business sector — you have all the recipes to succeed. But you have to roll up your sleeves."
Opportunity lies in adversity. During the Men's Olympic Football Tournament in London in 1948, the Indian team quite famously played barefoot and almost defeated France, earning praise from Princess Margaret. The task ahead for Indian football is no less gigantic than playing barefoot, and coming out triumphant will require equal, if not more, passion and resilience.
"I feel we all need to pull up our socks, why just the All India Football Federation (AIFF)?" Sunil Chhetri, India's football captain, said. "The players, government, corporate houses, AIFF, media, everyone needs to make India the hub of Asian football. The challenges would obviously lie in upgrading football infrastructure, developing players at grassroots and then funnelling them into top professionals. We should also make our leagues stronger so that we have good players coming into the national team. Our objective should be to do well in Asia first."
Looking ahead, two big opportunities present themselves to Indian football.
First, the Under-17 FIFA World Cup in 2017, which India has won the rights to host. Simply put, the country can ill-afford to do a 2010 Commonwealth Games with it. The future Ronaldos and Messis will be on display, along with the scouts. Unlike in 2010, every single individual that comes for the mega event should go back saying "India was great".
The second perceived catalyst is the newly-conceived Indian Super League (ISL), which promises to change the face of football in India. There lies the catchword: promises. The ISL is trying to do what the Indian Premier League did to cricket — take the game to a newer audience, thereby taking its popularity to another level. A host of celebrities, sportsmen and business honchos have bought a stake in the franchises of ISL, none less than Sachin Tendulkar, Sourav Ganguly, Salman Khan, Ranbir Kapoor, John Abraham and Atletico Madrid, a highly successful Spanish club.
Like most things radical, there are two sides to this. Many believe the influx of foreign stars, management, coaches, officials, and technical expertise will give Indian football some valuable inputs. But then there are people riding on the riders. Some I-League clubs are vehemently opposing the ISL, threatening to split Indian football in its very heart. Their reasoning is that there's no guarantee these franchises will actually invest in building infrastructure and players at the grassroots, and will focus only on marketing the game to pump in money. They also feel the league will have little or no impact in spurring the national team's performance.
The AIFF is banking on three 'P's to take Indian football forward: Promotion, packaging and presentation. "We see a bright light at the end of the tunnel," Subrata Dutta, senior vice-president of the AIFF, said.
"Indian football is in a transition stage and is progressing fast. The Under-17 WC and ISL will boost Indian football and accelerate commercialisation. But we need to make sure that the infrastructure is ready well within time."
Rahul Jha, a 23-year-old sports management student from Mumbai, tells us why Indian football doesn't have him hooked. "One follows international leagues because they are marketed well. Their ads invoke passion and triumph. Most of us would love for an Indian football league to be on par or even better than the cricket league."
However, former India player and president of the Football Players Association of India, Renedy Singh, has two simple mantras to get Indian football back on track: good quality coaches and focus on grassroots.
"There are a lot of plans being floated around, like the 'Lakshya 2022', but as long as you don't implement them, Indian football won't go anywhere. Everyone talks about the time frame that India will take to qualify for the World Cup. I don't see it happening for another 40-50 years," Singh said.
The Indian captain sees more positives for Indian football than negatives going forward. "The early feelers on ISL seem to look good. Similarly, India winning the rights to hold the U-17 World Cup will be huge. Overall, in the long term a lot of work needs to be done but the early signs are good. Football is a global game and I don't see a reason why India cannot play a major part in it," Chhetri said.
Well, the entire country seems to be smitten by optimism of the 'acche din aane wale hain' chant. Will that slogan hold true for Indian football as well? Only time will tell.
Till then, it's time to sit back and enjoy Brazinga 2014!


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Egypt's draft charter gets 'yes' majority in vote
CAIRO Egypt's Islamist-backed constitution received a "yes" majority in a final round of voting on a referendum that saw a low voter turnout, but the deep divisions it has opened up threaten to fuel continued turmoil.
Passage is a victory for Islamist President Mohammed Morsi, but a costly one. The bruising battle over the past month stripped away hope that the long-awaited constitution would bring a national consensus on the path Egypt will take after shedding its autocratic ruler Hosni Mubarak nearly two years ago.
Instead, Morsi disillusioned many non-Islamists who had once backed him and has become more reliant on his core support in the Muslim Brotherhood and other Islamists. Hard-liners in his camp are determined to implement provisions for stricter rule by Islamic law in the charter, which is likely to further fuel divisions.
Saturday's voting in 17 of Egypt's 27 provinces was the second and final round of the referendum. Preliminary results released early Sunday by Morsi's Muslim Brotherhood showed that 71.4 percent of those who voted Saturday said "yes" after 95.5 percent of the ballots were counted. Only about eight million of the 25 million Egyptians eligible to vote - a turnout of about 30 percent - cast their ballots. The Brotherhood has accurately predicted election results in the past by tallying results provided by its representatives at polling centers.
In the first round of voting, about 56 percent said "yes" to the charter. The turnout then was about 32 percent.
The results of the two rounds mean the referendum was approved by about 63 percent.
Morsi's liberal and secular opposition now faces the task of trying to organize the significant portion of the population angered by what it sees as attempts by Morsi and the Brotherhood to gain a lock on political power. The main opposition group, the National Salvation Front, said it would now start rallying for elections for the lawmaking, lower house of parliament, expected early next year.
"We feel more empowered because of the referendum. We proved that at least we are half of society (that) doesn't approve of all this. We will build on it," the Front's spokesman, Khaled Daoud, said. Still, he said, there was "no appetite" at the moment for further street protests.
The new constitution would come into effect once official results are announced, expected in several days. When they are, Morsi is expected to call for the election of parliament's lawmaking, lower chamber no more than two months later.
In a sign of disarray in Morsi's administration, his vice president and - possibly - the central bank governor resigned during Saturday's voting. Vice President Mahmoud Mekki's resignation had been expected since his post is eliminated under the new constitution. But its hasty submission even before the charter has been sealed and his own resignation statement suggested it was linked to Morsi's policies.


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Dirty laundry is not a good thing to hoist on your spars, so figure the cost of new sails in your future in that situation. Otherwise, synthetic sails that are quite old (10-15 years) can still look OK as far as wear & tear on seams and corners, etc. Determining if they''ve held their shape is another matter. A sail may be only used once, but if it was for a 2,000 mile trip in gale winds, you''ll need a new one. A sail that looks to have solid seams & little wear may be OK for cruising in the trades for another five years, but might not be suitable for a single race around the bouys next weekend because the shape isn''t quite right. If it looks OK to you, it probably is ok for what you plan to do. When you''re ready to think about new sails, get a sailmaker to have a look.
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Comelec set to release list of disqualified party-list groups
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MANILA, Philippines—The Commission on Elections is set to release a list of disqualified party-list groups by September, its spokesman said on Wednesday.
Comelec spokesperson James Arthur Jimenez told reporters the poll body cleanse the list by removing the unqualified groups from the existing 127 registered party-lists.
Jimenez said that only the qualified party-lists could continue serving their terms in the House of Representatives.
The Comelec is currently holding hearings with party-lists to determine whether their accreditation will be retained or cancelled.
Comelec has recently warned that Ang Galing Pinoy party-list, led by Representative Juan Miguel "Mikey" Arroyo, might be disqualified after it failed to appear in a Comelec hearing last week.
Jimenez saw this process to be useful in determining which party-lists rightfully represent the marginalized sectors. Comelec chairman Sixto Brillantes Jr. questioned how multi-millionaires are able to represent the poor.
Brillantes explained that they sought to understand how party-list lawmakers' pork barrel were being utilized and also wanted to scrutinize their Statements of Assets, Liabilities and Net worth (SALNs).
When Cagayan de Oro Representative Rufus Rodriguez questioned the process, Brillantes said that it was necessary to cancel the accreditation of some party-lists that are unqualified to represent marginalized groups.
Disqualified groups could file an appeal, said Jimenez.
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The Dravida Munnettra Kazhagam (DMK) has decided to go it alone in the local body polls scheduled to be held soon.
According to a statement from DMK president and former Chief Minister M. Karunanidhi, his party formed an alliance with likeminded parties for elections to the Lok Sabha and the Assembly in a bid to form a progressive government at the Centre and a democratic reime in the State.
Besides, the DMK was always careful that both at the Centre and the State no government that was "communal" and "anti-human" should be formed.
However, in the local body polls, the DMK had decided that it was not necessary to cobble together political alliances as there was no necessity to place political principles in front of the public but only basic necessities such as sanitation and health care, education, roads and drinking water.
"This decision has been taken after deep introspection," Mr. Karunanidhi added.
Keywords: Tamil Nadu local body polls, DMK-Congress alliance


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Hey !! Is anybody else having problems right now with this site ? I scroll down the list of topics to answer questions--
_and when I click on Arts & Entertainment for example , I don't get the current list of questions from people . All I get is a page of " Hottest questions today " . It's like that for "Current Events " , "Health & wellness " , " Education " ., " Family and Friends " i.e . ALL of them . Anyone else having this problem ?
Yes I do have that problem!The only ones it doesn't do that with are mature topics and other as far as I have noticed!
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Or is it my old computer with Windows XP ??
Is anyone else having problems typing longer answers? I can only get so far and I can't scroll down to see the rest.rag68 41-45, M 3 Answers 1 May 18, 2012


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Relay For Life in Henry County is quickly approaching, scheduled for Friday, June 26, at the Henry County High School Track. Relay For Life is the American Cancer Society's signature activity. It offers everyone in a community an opportunity to participate in the fight against cancer. Teams of people camp out at a local high school, park, or fairground and take turns walking or running around a track or path. Each team is asked to have a representative on the track at all times during the event. Relays are an overnight event, up to 24 hours in length.
A determined Brittany Crawford blasted out of the blocks, clipped the first hurdle and settled into a quick rhythm for the next nine as she closed in on the competition and finished with a perfect lean at the line. In a 100-meter hurdles race that was too close to call, it took a photo finish to decide the outcome.
Eminence Redskins
In his final outing wearing an Eminence uniform, Ed Berry wrapped up an impressive high school career with an eighth-place finish in the 200-meter dash, ninth in the high jump and 18th in the long jump at the Kentucky State Track and Field Championships at the University of Louisville on Saturday afternoon.
Staff writer/photographer
At the May meeting of the HCPS board, superintendent Tim Abrams asked the board to approve the 2009-10 district tentative budget.
"It's a good budget," he said. "It shows us being in sound financial condition."
Abrams said it is difficult to call it a great budget because although the district has a six percent contingency, future cuts at the state level could deplete the fund significantly. The district is required to maintain a reserve of at least two percent.
Emma Foree has lived on Crabb Ave. across from the Eminence Independent Schools' softball field for four years.
During games she has come to expect fouled-back softballs landing in her yard or closer.
Last year during tournament play a ball flew through an open window.
"That's something I can't explain to this day," she said. "The ball landed right on my son's bed."
Nineteen teams made up of 85 Henry County Biggest Losers are off to a great start! If you'd still like to join, call 220-3614. Achieve maximum weight loss for your team by encouraging your teammates and holding one another seriously accountable for the next nine weeks. No secrets are hidden from the scales!
Postmaster, New Castle
You probably know that the Postal Service is big. To be able to serve the mailing needs of every American every business day, we have to be big! But we bet you didn't know that:
Henry County's Reigning Biggest Loser
"Matter cannot be created or destroyed." As a seventh-eighth grade science teacher I know that this is true. If you exercise to burn off more calories than you consume, you have to lose weight. As the reigning Biggest Loser of Henry County, I challenge Henry County Local readers to join the next Biggest Loser Contest.
For 137 years, the oldest portion of Smithfield Baptist Church stood tall. It stands no more.
Reverend Ed Life said the old building finally had to come down.
The sign outside the church reads "Thank you, Lord, for 137 years in this building."
Copyright © 2015
The Henry County Local is your source for local news, sports, events, and information in Eminence, KY and the surrounding area.


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Jacques Molitor Plus
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I'm a European filmmaker, working mostly in drama.
films should stir thoughts about human relationships,
explore the limits of emotion
& haunt your brainwaves afterwards
Contact: email@example.com
Jacques Molitor was born in Luxembourg on February 15th, 1980.
After two years of medical studies, he enrolled at film school «Institut des Arts de Diffusion » (Louvain-la-Neuve, Belgium), where he obtained a degree with honors.
In 2003, Jacques took a trip to California for the summer production workshop « directing intensive » at prestigious University of Southern California USC. Lecturers: William H. Macy, Jerome Gary among others.
Jacques's IAD thesis project "GEMINI" is a bold mixture of traditional film and animation techniques and was screened at Korea's SICAF and Munich Student Film Festival.
In 2008, Jacques co-wrote and directed the ambitious short "En compagnie de la poussière / WITH THE DUST". This story of a failed gay romance, exploring the intersection of love and death, was screened in the official short competition at Locarno, as well as in numerous international festivals: Les Films du Monde in Montréal, Ghent, Dresden Filmfest, Torino LGBT, etc.
"With the Dust" has also been screened on the TV channel ARTE.
His third short film « BONOBO » (2009), a portrait of a man's self-destruction, shot on 35mm, was broadcast on France 2.
More recently, Jacques has conceptualized and shot the first commercial for AIDS prevention organisation "Paticka" and directed two episodes of the RTL sitcom "COMEBACK".
In his quest for perfection, Jacques attended workshops by Peter Webber ("Hannibal Rising") and script doctor legend John Truby.
The feature documentary "SWEETHEART COME" (produced by Red Lion), tackling unconventional sexuality and relationships in Luxembourg, was released to theaters in March 2013.
Jacques finished his first fiction feature MAMMEJONG, a coming-of-age story about a man-child who tries to sever the unhealthy ties that bind him to his mother to win the heart of a young, equally troubled girl. The project is supported by Luxembourg Film Fund and produced by Lucil Films (Lux) / Wrong Men North (Be).
More info: facebook.com/mammejong


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Comparison of a novel fast-dissolving acetaminophen tablet formulation (FD-APAP) and standard acetaminophen tablets using gamma scintigraphy and pharmacokinetic studies.
Summary of "Comparison of a novel fast-dissolving acetaminophen tablet formulation (FD-APAP) and standard acetaminophen tablets using gamma scintigraphy and pharmacokinetic studies."
Context: Acetaminophen (paracetamol, APAP) is widely used to relieve mild-to-moderate pain and reduce fever. Absorption of the drug can be impacted by dosage form; this may have implications for pain relief in some individuals, potentially accounting for suboptimal efficacy in analgesia. Objective: To assess the disintegration and dissolution of a new fast-dissolving acetaminophen tablet formulation (FD-APAP) and the impact on pharmacokinetic and pharmacodynamic parameters. Materials and methods: Two randomized, single-center, open-label, single-dose, two-way crossover studies in healthy subjects to compare FD-APAP (2 × 500 mg tablets) with standard acetaminophen (2 × 500 mg tablets). Gamma scintigraphy was used to assess tablet disintegration (Study 1, N = 24), and plasma profiles were evaluated in the fasted state (Study 2, N = 40). Results: In Study 1, the mean time to complete disintegration (12.9 vs. 69.6 min, P < 0.0001) and onset of disintegration were both significantly faster with FD-APAP than with standard acetaminophen (P < 0.0001). For Study 2, median T(max) was significantly faster for FD-APAP (0.50 vs. 0.67 h, P < 0.01) and AUC(0-30 min) was significantly greater (4.51 vs. 2.74, P < 0.05). AUC(0-t) and AUC(0-inf) were comparable between the two study treatments. Discussion: Despite the absence of comparative clinical data, the FD-APAP formulation may be expected to overcome some of the issues associated with the slow and variable absorption of standard acetaminophen tablet formulations, improving therapeutic outcome and avoiding the need to switch to alternative therapeutic options. Conclusion: Compared with standard acetaminophen, the FD-APAP formulation results in significantly faster onset of disintegration and more rapid absorption.
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
Journal Details
This article was published in the following journal.
Name: Drug development and industrial pharmacy
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21244275
- DOI: http://dx.doi.org/10.3109/03639045.2010.538058
PubMed Articles
A New Transmucous-Buccal Formulation of Acetaminophen for Acute Traumatic Pain: A Non-inferiority, Randomized, Double-Blind, Clinical Trial.
Acetaminophen (APAP) consumption is large and sometimes excessive, and guidelines suggest to diminish the dosage prescription. In emergency situations of mild/moderate pain intravenous (iv) APAP is re...
Protein-Derived Acetaminophen-Cysteine Can Be Detected After Repeated Supratherapeutic Ingestion of Acetaminophen in the Absence of Hepatotoxicity.
Generation of protein-derived acetaminophen-cysteine (APAP-CYS) is reported after ingestion of large and therapeutic dosages of acetaminophen in healthy and in liver-damaged patients. The incidence of...
Wuzhi Tablet (Schisandra Sphenanthera Extract) Protects Against Acetaminophen-induced Hepatotoxicity by Inhibition of CYP-mediated Bioactivation and Regulation of NRF2-ARE and p53/p21 Pathways.
Schisandra sphenanthera is widely used as a tonic and restorative in many countries to enhance the function of liver and other organs. Wuzhi tablet (WZ) is a preparation of an ethanol extract of Schis...
Metformin Ameliorates Acetaminophen Hepatotoxicity via Gadd45β-Dependent Regulation of JNK Signaling in Mice.
Acetaminophen (APAP) overdose is a leading cause of drug-induced acute liver failure. Prolonged c-Jun N-terminal kinase (JNK) activation plays a central role in APAP-induced liver injury, and growth a...
Protective effects of luteolin against acetaminophen-induced acute liver failure in the mouse.
Acetaminophen (APAP) is widely used as a safety analgesic and antipyretic agent. Although considered safe at therapeutic doses, overdose of APAP can cause acute liver injury that is sometimes fatal, r...
Clinical Trials
Evaluation of the Interaction Between Acetaminophen and Zidovudine
To determine if zidovudine (AZT) and acetaminophen (APAP) interact when given to the same patient, and if so, the manner of interaction. Patients with AIDS often require therapy with paink...
Study of the Safety & Efficacy of Intravenous Acetaminophen in Pediatric Inpatients
IV APAP is safe in repeated dose, multi-day clinical use when administered at a daily dose of 40 to 75 mg/kg body weight
Acetaminophen in aSAH to Inhibit Lipid Peroxidation and Cerebral Vasospasm
The objective of this study is to determine whether acetaminophen (APAP), N-acetylcysteine (NAC), and APAP in combination with NAC will inhibit lipid peroxidation in aneurysmal subarachnoi...
Study of the Efficacy and Safety of Intravenous vs Oral Acetaminophen for Treatment of Fever in Healthy Adult Males
To assess the rapidity of onset of antipyretic effect and the efficacy and safety of a single dose of IV APAP versus PO acetaminophen in the treatment of fever induced by a standard dose o...
Safety of Intravenous Acetaminophen Versus Placebo for the Treatment of Endotoxin-Induced Fever in Healthy Adult Males
A research study to determine if acetaminophen given intravenously (IV-a liquid given through a needle into a vein in your arm) is safe and effective in controlling fever when compared to ...
Medical and Biotech [MESH] Definitions
Cross-cultural Comparison
Comparison of various psychological, sociological, or cultural factors in order to assess the similarities or diversities occurring in two or more different cultures or societies.
Muscle Fibers, Fast-twitch
Skeletal muscle fibers characterized by their expression of the Type II MYOSIN HEAVY CHAIN isoforms which have high ATPase activity and effect several other functional properties - shortening velocity, power output, rate of tension redevelopment. Several fast types have been identified.
Comparative Study
Comparison of outcomes, results, responses, etc for different techniques, therapeutic approaches or other inputs.
Receptors, Amino Acid
Cell surface proteins that bind amino acids and trigger changes which influence the behavior of cells. Glutamate receptors are the most common receptors for fast excitatory synaptic transmission in the vertebrate central nervous system, and GAMMA-AMINOBUTYRIC ACID and glycine receptors are the most common receptors for fast inhibition.
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.


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An Unsolved Mystery of the Old WestThe legend of the Lost Lemon Mine is one of the most enduring unsolved mysteries of the Canadian West. In 1870, so the story goes, two prospectors named Lemon and Blackjack found gold in the rugged mountains of southwestern Alberta or southeastern British Columbia. Shortly after, Blackjack died at Lemon`s hand. The distraught Lemon left the scene of the murder and never recovered his senses—or his
Curse of the Mumy: Collected EditionHi dittle dee dee, an actor's life for me... There's a heavy price to pay when bringing a character to life, some might even call it... a curse. Ask iconic sci fi actor Bill Mumy (Lost In Space, Twilight Zone & Babylon 5). The Illuminati... secret Nazi moon base... the Akashic Records... a ghost boy... all this and Row Bot too. "The Curse of the Mumy"... an original new series from the pages of


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Installation Shots From Pangaea II: New Art From Africa And Latin America
Installation Shots From Pangaea II: New Art From Africa And Latin America
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Dealers and Galleries Home
Sample Gallery/Dealer Art Work - Westwood Gallery, NYC
Wall Fragment No. 93.11
Will Insley
Created On:
Image Medium:
acrylic on masonite
Image Dimensions:
204 x 204 cm
Art work Description:
New York, NY â Westwood Gallery is pleased to present a solo exhibition of artwork by New York artist, Will Insley (born 1929). ONECITY, envisioned by Insley is a 675 mile square architectural labyrinth of mythology buried in the central North American plains. It is designed as an imaginary city to house 400 million people of the time, considered the entire population of the United States. During the era of ONECITY the outer rim of the country is inhabitable, possibly due to environmental devastation. Westwood Gallery will exhibit 33 works of art by Insley. The drawings on exhibit represent architectural renderings of abstract buildings which surround ONECITY as vacant ruins to be abandoned after they are built. Insley created over 40 drawings of abstract buildings, originally shown in his exhibition at the Solomon Guggenheim Museum, NYC in 1984. The concept of ONECITY was contemplated for over 40 years by Insley, establishing not only an architectural layout consisting of over 14,000 outer city square buildings, each two and half miles wide, but an entire sociological order for the citizens of ONECITY. No visible leader exists, but a democratic voting system occurs every day, whereby residents vote on various matters. Instead of a vertical religious order, the inhabitants worship the horizontal line as a mythical space between earth and sky. The center of ONECITY holds the Opaque Library, âthe seed and soulâ which houses information and secrets, not accessible to the populace. Criminals are kept in an area known as the âNinth Arenaâ where they can eliminate one another and are the object of âTheatres of Deathâ. Also on exhibit are âWall Fragmentsâ, acrylic paintings which represent remnants from the walls of ONECITY. âIf there are wall fragments, there must be buildings; if buildings â a city, if a city â a civilization, if a civilization â a religion; -- all the ingredients to form a mythological contextâ â Will Insley. Through his wall fragments, drawings and photomontage, Insley explores an abstract civilization, created line by line using logic, dimension and spatial theories in combination with interrelationship of people living in a futuristic environment. Diane Waldman, Deputy Director, Guggenheim Museum, 1984 âBy means of his geometric imagery he explores the potential of an architecture unlimited by the restrictions of reality; perhaps paradoxically, through the cool and rational appearance of his art he elaborates the myth of a dark and mysterious civilization outside of normal timeâ. Will Insley was born in Indianapolis, IN in 1929. He lives and works in New York City. He graduated from Amherst College with B.A. in 1951 and from Harvard Graduate School of Design, M.A. Architecture in 1955. His work has been exhibited by over 70 museums, including Museum of Modern Art, NYC, Solomon Guggenheim Museum, NYC, Whitney Museum of American Art, NYC, Albright Museum of Contemporary Art, Ridgefield, CT, as well Kunsthalle Basel and Fondation Maeght, Saint-Paul de Vence, France, Dokumenta Kassel and the Venice Biennale and is in numerous collections. His artwork has been reviewed extensively in publications, such as ARTnews, Art in America, The New York Times and documented in the reference book, The New American Abstraction 1950-1970 by Claudine Humblet.
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Kia's compact connects
Stylish Forte sedan challenges Toyota and Honda models
Kia is pushing limits and raising expectations with its new compact Forte sedan.
The 2010 Forte, which replaces Spectra, could cause Toyota to put some style in the next Corolla and make Honda look over its shoulder to protect the Civic's turf.
Forte — pronounced For-tay — is the first compact, Kia says, to offer a USB port, satellite radio and Bluetooth phone connection as standard equipment. Also standard are safety features such as six air bags, electronic stability control, traction control, ABS, brake assist and electronic brake force distribution.
Available in LX, EX and SX models, prices range from $14,390 to $18,890. The EX test car has a starting price of $17,490 and was $18,090 with the Fuel Economy Package, $600.
The LX is the price leader with crank windows, limited color choices and limited access to conveniences. The EX piles on the extras, and SX pushes sportiness with a slightly larger engine, tighter suspension and larger front brakes and 17-inch wheels with performance tires.
The fuel economy package applies such refinements as a five-speed automatic, electric power steering and "silica" tires to stretch mileage to 27/36. The 16-inch, low-rolling resistance tires can be noisy on concrete highways, but that is more than overcome by the six-speaker audio system with steering-wheel controls.
Forte's cabin architecture pushes limits for size — 40 inches of headroom, 43.3 inches of legroom in the front and 35 inches of rear legroom, on a three-seat bench that doesn't cheat on thigh support or comfortable back angle. The trunk is wide and accessible with 14.7 cubic feet of space.
A folding back seat is standard on EX and SX, optional on LX. A fold-down armrest with cup holders is a good territory divider for siblings. Missing from the back seat is a head restraint at the center position.
Kia is also showing ability in design. The Forte is an attractive car with interesting lines and angles that won't appear gimmicky and tired before the warranty expires, which is five years for basic coverage and 10 years for powertrain.


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Search the collections
Where is it from?
- A Addressed To London, United Kingdom
- B Author Fitzroy, Australia
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Letter - J Ash to AG Maclaurin, 8 Dec 1927 Reg. No: HT 8299
- Summary:
- Letter from John Ash, General Manager of the Commonwealth Bank Note Printing Branch Fitzroy, to Archibald Gordon Maclaurin, dated 8 December 1927. The letter is in regards to Archie's request for information regarding employment opportunities and working conditions in Australia. Ash provides details of pay, hours and leave but expresses inability to employ machinists at present. However he does offers assistance to help Archie secure employment at McLaren's printers until he can take him into his employ. Ash also explains his inability to assist with Archie's fare due to Victorian regulations regarding importing labour. However he notes that if Archie can pay his own way, he will be compensated through wages. Ash describes the working conditions and climate as superior to London, Melbourne as beautiful and the lifestyle all together an improvement on London.
Archie was born in 1904 in Westham London. He trained as a printer and sought work in Australia as there were few opportunities in England; he migrated on the 'Jervis Bay' in 1928. Before migrating he commenced negotiations with the general manager of the Commonwealth Bank Note Printing Branch Fitzroy, who assisted Maclaurin in securing employment at McLaren & Co Pty Ltd Colour Printers in Fitzroy. He then moved to Spicers & Depmont Printers and Stationers before an opening came up for a machinist at the Note Printing Branch, where he worked for 32 years.
He married Constance Duffell in 1934, who had migrated from England on the 'Narkunda' with her parents and brother in 1927. Her father and brother worked for the Note Printing Branch which facilitated their meeting. They had two children, Roger and Jocelyn and lived all their lives in Essendon.
- Description:
- Two sided hand written letter on ruled paper to Maclaurin from John Ash, Commonwealth Bank of Australia Bank Note and Security Dept, Fitzroy, Melbourne, dated 8 December 1927.
- Acquisition Information:
- Donation from Mrs Jocelyn Maclaurin, 2004
|20.15 cm (Width), 26.00 cm (Length)
More information
|Tagged with:
|british immigration, immigration, printing industry, correspondence, printing, employment
|Themes this item is part of:
|Domestic & Community Life Collection, Migration Collection, Transport Collection, Working Life & Trades Collection, Archibald Gordon Maclaurin, English Migrant, 1928
|Primary Classification:
|Secondary Classification:
|Processing - Planning & Departure
|Tertiary Classification:
|Addressed To:
|Archibald Maclaurin, London, England, Great Britain, 8 Dec 1927
|John Ash - Commonwealth Bank Note Printing Branch, Fitzroy, Victoria, Australia, 8 Dec 1927
This item is part of the following themes:
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Welcome USF Faculty! We know how busy things can be during a semester but just a few dates to remember:
Ready to submit an order online?Just go to our Online Adoption site! (tutorial available)*NOTE: This site is NOT affiliated with USFConnect; first-time users must register;the Bookstore Supplied Password is: 0864 (you will only need this once; you'll be asked to create your own password afterward)*Please contact the Bookstore if you're having problems accessing the site or need a password reset.
Soon the Spring semester will end and we'll find ourselves with (hopefully) a lot more free time to take in the day and relax!
While the end of the semester happens, we can get too caught up in it and forget to focus on tomorrow.
So don't forget there is still a Summer term and, next thing you know, Fall term will be upon us. Please make sure you're submitting those book orders and ensuring your students won't be caught unprepared because they didn't know what course materials were needed or couldn't get them because no orders were placed!
But! Don't forget to also take a moment for yourself! While the summer can still be stressful and busy, find some time in the day just for yourself: catch up on a good book, go see a movie, or even just find a nice spot in the park to soak it all in..
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NBI chief quits
More News from Jamie Elona, Kristine Sabillo
More News from INQUIRER.net
MANILA, Philippines – National Bureau of Investigation Director Nonnatus Rojas has tendered his irrevocable resignation, Justice Secretary Leila de Lima said on Monday.
Rojas' resignation came after President Benigno Aquino III himself disclosed that charges are being readied against two NBI officials who had allegedly tipped off Napoles about the warrant of arrest issued against her last August 14.
While the resignation was irrevocable, De Lima said it would still be subject to the President's approval though she said she would recommend to Aquino not to accept it, saying that the NBI chief still has her trust.
"It goes to show that he (Rojas) is very principled. It goes to show that he has delicadeza na kahit alam niya at in-explain ko na na hindi ikaw ang tinutukoy ng Pangulo," De Lima said.
(It goes to show that he is very principled. It goes to show that he has delicadeza even if I have already explained to him that he wasn't the one being referred to by the President)
In interview with Inquirer editors and reporters Thursday, Aquino said the two NBI officials had ties to senators implicated in the scam allegedly masterminded by Janet Lim-Napoles.
The President refused, however, to name the two though reports said they were the ones who had tipped off Napoles' impending arrest even before a warrant was actually issued.
On August 28, Napoles surrendered to the President after he announced the P10 million bounty for anyone with information leading to her arrest.
The NBI has been building a case against Napoles and others linked to her alleged bogus non-government organizations which were used to channel P10 billion Priority Development Assistance Fund (PDAF) known as "pork barrel."
Aquino said the team building the case is "a very trusted team" but they "could not be tasked" to do other work such as surveillance.
In fact, he said, both Rojas and De Lima have to contend and sometimes rely on "less trustworthy" agents because the NBI is severely undermanned.
Related Stories:
Raps readied vs 2 NBI execs who tipped off Napoles
Janet Napoles and the pork barrel scam
Originally posted: 12:39 pm | Monday, September 2nd, 2013
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S.R. Ashok Kumar
Singers perform some of her most memorable numbers
CHENNAI: It was a memorable evening of the enchanting music of noted singer of yesteryear L.R. Eswari, who was felicitated here on Tuesday.
She was presented with a gold medal by Mrs.Y.G.Parthasarathy, dean, Padma Seshadri Bala Bhavan group of schools.
Immortal songs
Fans continue to be mesmerised by the immortal songs of L.R. Eswari, such as 'Pattathu Rani' (the function was titled after this song). Show anchors Y.Gee. Mahendra and ARS provided interesting insights into the singer's life and explained how some of her melodies were recorded. Some enjoyable numbers performed were 'Palingu Nan Oru' (Vallavan Oruvan), 'Malarendra' (Kadhalikka Neramillai) and 'Adavarellam' (Karupuppanam).
Singers who performed at the show, organised jointly by Madhu Enterprises and Alandur Fine Arts, included Malathi Lakshman, Madhuvanthi, Madhumitha, Suchitra, Prasanna, T.M.S. Balraj, Kovai Murali, Thyagu, Sainthavi, Madurai Kavitha, Sudha, Sabitha and Raja.
Veteran playback singers T.M. Soundararajan, S. Janaki, A.L. Raghavan, and actors M.N. Rajam and Sachu were present.


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India today sought investments from Singapore in its infrastructure and connectivity projects along the ambitious Delhi-Mumbai and Chennai-Bangalore industrial corridors as well as in the North Eastern region.
Kicking off an year-long celebration to mark 50th anniversary of the establishment of bilateral diplomatic ties jointly with her Singaporean counterpart K Shanmugam, External Affairs Minister Sushma Swaraj said the occasion will be used to advance economic engagement, defence and security cooperation between the two countries.
Noting that Singapore is not only India's largest trading partner in ASEAN, but also one of the largest source of foreign investment globally, Swaraj said the two countries can achieve anything if they open their imagination.
On his part Shanmugam, appreciated role of India which was one of the first countries to diplomatically recognise Singapore. He also observed the significant contribution made by the Indian diaspora in Singapore's economy and culture.
After reading out her prepared speech in English, Swaraj broke into Hindi, taking audience by surprise who responded the Minister's gesture with a huge round of applause.
During her Hindi remarks, the Minister said that there are a lot of expectations from the new government in India which has come into power with a huge majority after a long gap and assured them that they will try to fulfil the same.
Ahead of the inauguration of the celebration, Swaraj also interected with the Indian diaspora, present in huge numbers at the event to greet her.
"The commemoration of 50 years of diplomatic relations between our two countries is not just a celebration of what we have achieved so far, but also an opportunity to push the envelope to find and develop new areas to deepen our engagement," Swaraj said in her address.
Seeking enhanced investment from Singapore, she said both the countries should also look at scope of venture capital for innovations and for cooperative projects in third countries.
"We look forward to Singapore companies to speed up connectivity and infrastructure projects in India, particularly, along the Delhi-Mumbai Industrial Corridor (DMIC), the Chennai-Bangalore Industrial Corridor and the North-East. Singapore could develop a virtual city or a 'little Singapore' somewhere along the corridor," she said.
The External Affairs Minister said improving connectivity was a priority area for India's new government and suggested launch of air-connectivity between Singapore and the north eastern city of Guwahati.
"Singapore's expertise in Smart Cities, urban planning and water management strategies offer a valuable learning experience for India. We shall work for setting up greenfield Smart Cities and for urban rejuvenation. Our experts shall identify the priorities and we shall coordinate its timely delivery," she said.
Swaraj said the world class skill development centre in Delhi, set up by Singapore, was a model for similar centres in the rest of the country.
"I see our emerging relations as one in which the cultural content can be enhanced considerably and can become one of the new pillars of our robust relationship," she said.
The External Affairs Minister said Singapore has played a key role in the revival of the Nalanda University in Bihar and expressed happiness that the country will contribute to the library of the university.
"I am also pleased to announce that we shall be gifting a bust of Netaji Subhash Chandra Bose to the India Heritage Centre, to be established by the Singapore authorities," she said.
Earlier, during their meeting, Swaraj and Shanmugam agreed that the main highlight of the 50th anniversary celebrations will be the exchange of State Visits by Singapore's President Tony Tan to India and India's President Pranab Mukherjee to Singapore in 2015.
The celebrations will feature a "Festival of Singapore" in India and the "Year of India" in Singapore.
India and Singapore had established diplomatic relations on August 24, 1965. "During the year-long activities, we shall try to open windows to India which we hope will leave the viewer wanting more. This will be an important pillar of our emerging relations," Swaraj said.


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Archives for "South America"
February 12, 2010 9:39 am
Activists to discuss indigenous politics, environmentalism in the Americas at Bates College
The politics and environmental interests of indigenous peoples in the Americas, including Native Americans from Maine, are at issue in two nights of panel discussions at Bates College at Monday, Feb. 22 and Tuesday, Feb. 23.
October 30, 2009 12:50 pm
Bates' Language Arts Live series events span November
Longtime Maine poet Theodore Enslin and poet-artist-filmmaker Cecilia Vicuña take part in the Bates College Language Arts Live series in November. Featuring noted writers reading from their work, Language Arts Live events are open to the public at no cost. The series is sponsored by the English department, the environmental studies and Spanish programs, the Learning Associates Program, the Bates Humanities Fund and the John Tagliabue Poetry fund. For more information, contact email@example.com.
October 27, 2009 12:04 pm
Global Lens film series concludes with Brazilian film Margarette's Feast
The Global Lens film series at Bates College concludes with "Margarette's Feast", a film from Brazilian director Renato Falcão. The film will be shown at 8 p.m. on Friday, Dec.11, and Sunday, Dec. 13, in the Olin Arts Center, Room 105, 75 Russell St.
August 4, 2009 2:36 pm
Manbi, Ecuador
This photo was taken in the province of Manbi on the coast of Ecuador. After a long hike through the bosque seco and bosque nublado we stopped to cut platano and bananas to bring down to the house for our Ecuadorian-American feast.
July 23, 2009 9:27 am
Tania Isaac Dance presents Bates Dance Festival premiere
A visually explosive, sensual marriage of modern American and Caribbean aesthetics, Tania Isaac Dance brings its newest evening-length work to the Bates Dance Festival in performances at 8 p.m. Friday and Saturday, July 24 and 25, in Bates College's Schaeffer Theatre, 305 College St.
Tickets are $20 for the general public and $12 for students and seniors, and can be purchased by calling 207-786-6161. Dance writer Debra Cash offers a pre-performance lecture in the festival's "Inside Dance" series at 7:15 p.m. on the 25th.
March 26, 2009 10:54 am
Writers from Equatorial Guinea to speak
Four writers from Equatorial Guinea, the only Spanish-speaking nation in Africa, visit Bates College to give a joint presentation titled "Writing Africa in Spanish: Four Equatorial Guinean Writers Speak of Exiled Dreams" at 4:15 p.m. Tuesday, March 31, in the Edmund S. Muskie Archives, 70 Campus Ave.
March 19, 2009 4:40 pm
Cultural activists from South America to speak at Bates
Marfa Inofuentes and Rosana Silva Chagas, cultural activists from Bolivia and Brazil, speak at Bates College on March 23. The event is co-sponsored by the Caribbean Cultural Center African Diaspora Institute and the Arturo Schomburg Afro-Latino Speaker Series, a program of the Bates Office of Multicultural Affairs.
November 5, 2008 12:11 pm
Global Lens 2008 film series continues with Argentinian, Iranian entries
The Global Lens 2008 film series, a touring program of narrative feature films from Latin America, the Middle East, Africa, Europe and Asia, continues at the Olin Arts Center, Bates College, this week with 7 p.m. screenings of the 2006 Iranian drama 'The Fish Fall in Love' on Wednesday, Nov. 5, in Room 104, and 'Kept and Dreamless' (Argentina, 2005) on Thursday, Nov. 6, in Room 105.
November 1, 2008 9:24 am
Feeding the Bobcat
Sylvan Ellefson '09 and his Nordic teammates trust the Bates food chain.
November 1, 2008 9:20 am
Cornfield as Classroom
Food-oriented community projects provide more than physical nourishment.


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Over the summer, a Seattle University Professionals Without Borders team traveled to Chirundu, Zambia to implement a senior design project. The project was conceived by Father Bert Otten, SJ, Emeritus Professor of Electrical and Computer Engineering, who now lives in Zambia. With only 21% of the people in developing countries have access to electricity; the project was to test a unique way to deliver power to rural developing countries.
Seattle University students installed a waterwheel electrical generator on the Zambezi River in Chirundu, Zambia. During their senior year, the Electrical and Computer Engineering students designed and completed extensive testing to determine the power characteristics of the generator. A prototype of the generator was constructed to design and test the controls, transmission, and an appropriate way to store the generated power.
The installation uses simple, appropriate technology to deliver renewable electricity to rural communities on larger rivers in Zambia. Using a commonly available washing machine motor and simple electronics to charge batteries, the system is more cost effective source of power than the equivalent solar panels in this rural part of Africa. This electrical system is easy to maintain and can be recreated in other communities. The total cost, including the construction of the waterwheel is less than the solar panel equivalent. The waterwheel platform was developed for a spiral pump by a Seattle University Senior Design team in 2009
The installed generator system includes a generator, controls, protection, and a battery system. The battery system can be used for a variety of purposes, including charging cell phones, operating pumps and other electrical devices.
In picture: Senior Design Project Installation Team: Nowell Ancheta, Colin O'Brien, Steve Szablya, Faculty Advisor
Other Project Team Members, not in Zambia:Jeremy DeibellAndrew Sprenger
Industry Advisors
Byron LynchMark Beggs, BSCE 2012Meghan Reha, BSME 2009 (on the original 2009 team)Renee Vandermause BSCE 2013Jeff Wilhite, Staff SUDeLaunde Hopkins, Staff SU
2014 Projects Day was a great success with over 34 Senior Design Project Teams! Check out the photos and download the Projects Day 2014 Program
2013 Projects Day was a great success. Check out photos and the complete 2013 Projects Day Program
SU Project Center 25th Anniversary Video
SU Project Center 25th Anniversary Video (short version)
Engineering Project Testimonial
MBA Project Testimonial
Working as a faculty advisor on student projects helps me to expose my students to an entirely new range of skills that they will need when they become practitioners in their chosen fields. Project management, teamwork, communication, translating academic knowledge to reality are skills that set our students apart. The partnerships we've built with sponsoring organizations provide valuable professional connections for students and faculty alike.
- Teodora Rutar Shuman, Chair, Mechanical Engineering
Nondiscrimination Policy | Diversity Statement
RSS | Contact | Careers | Public SafetyThe Project Center is operated by the College of Science and Engineeringand the Albers School of Business and Economics.
901 12th Ave, P.O. Box 222000
Seattle WA 98122


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Sanctuary Medical Center Now Offering MiraDry
Advanced Treatment for Excessive Underarm Sweating Now Available in Ft. Lauderdale
Ft. Lauderdale, FL (PRWEB) June 10, 2013
The Sanctuary Medical Center of Ft. Lauderdale, Florida, is pleased to be one of the first centers in South Florida to perform miraDry, an advanced treatment for excessive underarm sweating.
MiraDry is an exciting new procedure approved by the FDA for the treatment of excessive underarm sweating, a condition known as primary axillary hyperhidrosis. This is a common condition which affects both men and women of all ages. Excessive sweating can be embarrassing and even debilitating, affecting one´s social and professional lives and also limiting clothing options. MiraDry is the latest and most effective treatment for primary axillary hyperhidrosis, providing immediate and dramatic results that last.
The renowned medical aesthetic center Sanctuary Medical Center is pleased to now offer this exciting new treatment at their Ft. Lauderdale location. Performed in the office setting, treatment with miraDry takes about forty minutes to complete using a local anesthetic for the patient´s comfort. During the treatment, a special hand piece is used which delivers microwave energy to the armpit area, precisely targeting and disabling the underlying sweat glands while simultaneously cooling the surrounding outer layers of skin for maximum comfort and safety. Patients experience little to no downtime and immediate results with an average 82% reduction in underarm sweat. For optimal results, a series of two treatments performed at three-month intervals is typically advised.
The Sanctuary Medical Center of Ft. Lauderdale is the premier destination in South Florida for total body rejuvenation and enhancement. Staffed by renowned plastic surgeons, dermatologist, age management specialists and other medical professionals, SMC offers a full array of surgical and non-surgical cosmetic procedures, including Botox and injectable fillers, anti-aging therapies, body treatments like Cellulaze and CoolSculpting, sclerotherapy, dermatology treatments including acne and skin cancer treatments, laser skin treatments, skin care, plastic surgery and more. To contact Sanctuary Medical Center of Ft. Lauderdale, Florida, call (954) 266-5512 or visit them online at http://www.smacboca.com/fort-lauderdale.html.
For the original version on PRWeb visit: http://www.prweb.com/releases/prwebMiraDryFtLauderdale/SanctuaryMedical/prweb10806644.htm