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|Mon - Fri
|10:30 am
|7:30 pm
|10:30 am
|5:30 pm
|- Closed -
Online bookings let you pick date/time for your visit.
If you purchase an eVoucher you will need to book with the venue directly.
Our old Wahanda Gift Vouchers can still be redeemed at over 3,000 locations. Use them to pay as you would with cash. Please note, the Wahanda Gift Voucher's successor – the Wahanda Gift Card – can only be used for online purchases.
My name is Anna and I'm a fully qualified beauty therapist and nail technician offering a range of treatments at your choice of location. I am happy to visit clients in the comfort of their own home or, if it's more convenient for you, i am happy to invite you in my salon located in Luton, 53 High Town Road.
I cover North London, NW London, the Bedfordshire and Hertfordshire area including Harpenden, Milton Keynes,High Wycombe, St Albans and much more. Please text me and ask about traveling in your location as i can cover more areas.

subset: commoncrawl


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Womens' easy tam with a "cabled" accent.
Designer Laura IrwinFinished Size 20" circumference. To fit 21½– 23" head circumference.
Yarn Plymouth Baby Alpaca Grande (100% baby alpaca; 110 yd [101 m]/100 g; Chunky #5 Bulky): #401 gray, 2 skeins.
Needles Size 7 (4.5 mm), size 8 (5 mm), size 9 (5.5 mm), and size 10 (6 mm). Adjust needle size if necessary to obtain the correct gauge.
Notions• 2 locking-ring markers;• tapestry needle.
Gauge 22 sts and 20 rows = 4" in rib patt on largest needles.
This pattern is from one of my favorite knitting books, Boutique Knits by Laura Irwin. This hat is perfect. Sweetly vintage chic and cozy warm for the most fridgid winters. A quick knit but always with some sort of patterning or shaping to keep it from getting boring. The entire book is great...if you like this hat, check it out.
Great hat but no pattern that I can find. What the.......this is listed under "free patterns". Can you tell me where to get it? Thanks. Carol
Is there a place to get the pattern for this hat? email@example.com
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Hotels close to Williamston - hotels.com offers the best selection of hotels near Williamston at low competitive prices. Compare the best hotel rates for room bookings close to Williamston and enjoy last minute deals. Book your ideal hotel room today with hotels.com secure online reservation tool and look forward to comfort & quality.
Hotels near Williamston
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Hotels in Williamston
- Most booked
Hampton Inn Williamston
Excellent 4.3 / 5 ( 89 reviews )
Most recent review
"Great hotel, very clean and nicely keep updated. All staff very friendly and very helpful and it had a good stocked breakfast bar including hot and cold breakfast foods, with coffee available all day."
A Traveller, Apr 2015, US
Econo Lodge Williamston
Good 3.8 / 5 ( 49 reviews )
Most recent review
"It was great. The staff was very friendly. The hotel was very clean some of the best sleep I've had"
A Traveller, May 2015, US
Holiday Inn Express Williamston
Excellent 4.3 / 5 ( 35 reviews )
Most recent review
"We had a wonderful time. The staff was upbeat and very helpful. Our needs were addressed promptly. Would love to stay there again. Breakfast was good and filling. That was my main request."
A Traveller, May 2015, US
Days Inn Williamston Nc
Good 3.2 / 5 ( 32 reviews )
Most recent review
"we stayed there because my daughter graduation from ECU and no hotels room available in Greenville NC. the price was very Cheap so i wasn't expecting much. I was surprise at the cleanliness of the rooms and how comfortable the beds were. was very happy with my stay... Front desk people were v..."
A Traveller, May 2015, US
Hotels within 28 kilometers of Williamston
Holiday Inn Express Plymouth
Excellent 4.0 / 5 ( 38 reviews )
Most recent review
"Very clean, quiet room, jacuzzi tub, good breakfast, helpful front desk. Pool not open yet, and booking agent should have told me this. Walk-ins evidently received same rate as I did using Hotels.com and were given choice of 1st floor, while I was not. Overall a decent value and we're happy w..."
A Traveller, May 2015, US
Hampton Inn Washington
Excellent 4.4 / 5 ( 53 reviews )
Most recent review
"No reason for this place to be any less than 4 or 5 stars. Clean, friendly good value. I liked it just fine. Better than many HI I have stayed in."
A Traveller, Feb 2015, US
Comfort Inn Washington
Good 3.3 / 5 ( 34 reviews )
Most recent review
"The room was clean and the bed was very comfortable. The only problem I really had with our room was we were surprised at 1 in the morning when our smoke detector in our room went off and our room had this burnt smell in it. We were sleeping and it made us shoot out of bed. I'm guessing it wa..."
A Traveller, Sep 2014, US
Hotels within 29 kilometers of Williamston
Econo Lodge North
Fair 2.8 / 5 ( 5 reviews )
Most recent review
"The bed was too hard for my wife, but fine for me. Clean overall. Location was good, near shopping and highway. Lady at the desk was very nice and helpful. AC was a little noisy but plenty cool. It is what it is -- Econo Lodge. I got a good nights rest and a shower. I don't need a sauna and f..."
A Traveller, Jun 2014, US
Hotels within 30 kilometers of Williamston
Magnuson Hotel Washington
Good 3.1 / 5 ( 54 reviews )
Most recent review
"we had been traveling by car and we were so tired, when the hotel clerk said she was checking me in over the phone i was so happy. when we arrived she had keys and room waiting for us. thanks for having such warm and understanding staff"
A Traveller, Feb 2015, US
Days Inn Washington Nc
Fair 2.8 / 5 ( 42 reviews )
Most recent review
"Decent hotel at a great price, we travel to the area a few times a year to visit family."
A Traveller, Dec 2014, US


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Date: 04/05/2013
Time: 7:00 PM - 9:00 PM
Location: Lloyd Ultan Recital Hall - Ferguson Hall
Cost: Free
A concert organized together with the current Government of Finland/David and Nancy Speer Professor in Finnish Studies, Matti Jutila (department of political science). Reception to follow.
The trio Suo is an exemplary product of the strong New Folk Music movement of Finland. Their music digs deep into the landscape of archaic "runo" singing: the rich language of the Finnish national epic Kalevala, the fascinating myths and spells, and the ageless flow of kantele music (kantele = Finnish national instrument of the zither family). Interpreted by three graduates of the Sibelius Academy music university, this forgotten music becomes alive and gets injected straight into your spine: the energetic guitar of Roope Aarnio, the nimble fiddle of Emilia Lajunen and powerful voice of Veera Voima will take you on an unforgettable journey.
Finnish-American musicians Sara Pajunen (violin) and Jonathan Rundman (guitar, harmonium, piano) explore their Nordic roots in the progressive acoustic folk duo Kaivama. The band's pyrotechnic agent is Sara Pajunen with her masterful fiddling. Pajunen's skills as a violinist have earned her degrees from the University of Minnesota and the Helsinki Conservatory in Finland, but she has transcended this classical background to become of one North America's most notable progressive folk fiddlers. Jonathan Rundman frames Pajunen's firepower. A veteran performer and recording artist, Rundman has toured the US and Europe as a troubadour songwriter, collecting raves from publications such as Paste, Billboard, and the New York Times.
Hosted by Finnish visiting professors Matti Jutila (political science) and Erkki Huovinen (music). Supported by the Government of Finland, David and Nancy Speer, and the University of Minnesota School of Music.
Hosted by Finnish visiting professors Matti Jutila (political science) and Erkki Huovinen (music). Supported by the Government of Finland, David and Nancy Speer, and the University of Minnesota School of Music.
More on the performers: www.suomusic.net, www.kaivama.com
Convenient parking is available at the University's 19th Avenue and 21st Avenue parking ramps; you must pay a fee to park in these ramps. More information is also available on the University Parking and Transportation Services website.
Reservation Information:
This event is free and open to the public. Tickets and reservations not required. Seats are available on a first-come, first-seated basis.
Disability Options:
To request disability accommodations, please contact Lisa Marshall, School of Music, 612/626-1094 or email@example.com.


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Which sex is the worst about washing up? Why is it so important? We've got the dirty truth on how and when to wash your hands.
Rotator Cuff Disorders
Gerdesmeyer L, et al. (2003). Extracorporeal shock wave therapy for the treatment of chronic calcifying tendonitis of the rotator cuff. JAMA, 290(19): 2573–2580.
Other Works Consulted
American Academy of Orthopaedic Surgeons and American Academy of Pediatrics (2010). Impingement syndrome. In JF Sarwark, ed., Essentials of Musculoskeletal Care, 4th ed., pp. 295–300. Rosemont, IL: American Academy of Orthopaedic Surgeons.
Lin KC, et al. (2010). Rotator cuff: 1. Impingement lesions in adult and adolescent athletes. In JC DeLee et al., eds., DeLee and Drez's Orthopaedic Sports Medicine, Principles and Practice, 3rd ed., vol. 1, pp. 986–1015. Philadelphia: Saunders Elsevier.
Wiesel BB, Carroll RM (2010). The shoulder. In SW Wiesel, JN Delahay, eds., Essentials of Orthopedic Surgery, 4th ed., pp. 323–351. New York: Springer.
WebMD Medical Reference from Healthwise
Rotator Cuff Disorders Topics
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Students at a New Zealand elementary school are using a suite of donated iMac computers as part of their classroom instruction. Among other things, students are playing maths games, sending e-mail, watching videos and typing stories on the computers. Educators say the technology benefits students, some of whom may not have access to such technology at home.
View Full Article in:New Zealand Herald, The
Published in Brief:


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Cycle Hire Widget Lite
50,000 - 100,000 downloadsAdd this app to your lists
+ By Little Fluffy Toys Ltd
Find your nearest cycle hire location with this compact homescreen widget, featuring live availability of bikes and slots at each location.
Rated "Best Cycle Hire App" by CNET and The Londonist, "App of the Week" by PC Pro, and "stunning" by The Guardian. Also featured by Google as both an Android app surgery and an App Engine case study.
Supported cities:
+ London (TfL Barclays Cycle Hire)
+ New York City (Citi Bike NYC)
+ Washington DC (Capital Bikeshare)
+ Boston, MA (Hubway)
+ Minneapolis, MN (Nice Ride Minnesota)
+ Paris (Vélib)
+ Marseille (Le vélo)
+ Lyon (Vélo'v)
+ Lille (V'Lille)
+ Toulouse (VélôToulouse)
+ Nantes (Bicloo)
+ Bordeaux (VCUB)
+ Aix-en-Provence (V'hello)
+ Amiens (Vélam)
+ Besançon (VéloCité)
+ Cergy Pontoise (VélO2)
+ Créteil (Cristolib)
+ Mulhouse (VéloCité)
+ Nancy (Cyclotop)
+ Rouen (Cy'clic)
+ Valence (Libélo)
+ Barcelona (Bicing)
+ Seville (Sevici)
+ Valencia (ValenbiSi!)
+ Saragossa (Bizi)
+ Santander (Tusbic)
+ Dublin (dublinbikes)
+ Melbourne (Bike Share)
+ Brisbane
+ Brussels (Villo!)
+ Luxembourg city (Vel'oh)
+ Milan (BikeMi)
+ Rio de Janeiro (SAMBA)
+ Toyama (Cyclocity)
+ Stockholm (City Bikes)
+ Gothenburg (Styr + Ställ)
+ Toronto (Bixi)
+ Montréal (Bixi)
+ Ottawa-Gatineau (Capital BIXI)
Common questions such as "why does a fast hybrid positioning system require wi-fi?" or "why can't any apps that contain widgets be installed to SD card?" are answered in menu-help - anything else, please email us at firstname.lastname@example.com
If you like this Lite version, please buy the full version, which features better data refreshes, favourites, no adverts, support for the Sony Ericsson LiveView second screen hardware device (check out the video at http://bit.ly/LFT-LV), and by helping us pay for our App Engine server charges it's good karma for the day.
Tags: cycle hire widget lite, cycle, cycle hire widget lite full, cycle hire widget lite vs full, bike hire service advertisement, widget cycle text, valenbisi valencia espanja, lication velib barcelone montreal, widget bike html, cycle hire widget.
Added support for NYC's CitiBike
(69 stars)
Better than the Barclay's app imho
(69 stars)
London use is good. Just one infuriating thing... Double tap on the map doesn't zoom in... Unlike every map ever. Updates quickly.
(69 stars)
Works well. Like the widget. Colours not obvious though.
(69 stars)
Doesn't even show the right number of cycles / slots. Wasted 15 minutes because of this app. Right now Barclay's own free app shows 0 bike slots and this useless app shows 3 slots available. Fake.
(69 stars)
(69 stars)
Pleased so far!
(69 stars)
When opening the app WiFi is automatically enabled. Needs a option to diamante disable this. Map appears buggy when zooming in/out. Apart from the bugs, its a good useful app.


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Moonpig, Mothers Day And Other Gifts – Spring Collection
Moonpig is a name I associate with those silly cards and mugs that you can embed a picture of a loved one of friend on … seems I was totally off the mark . Last week I headed up to London to view their Spring collection. Oh wow, was I … Continue reading


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Prices and availability are subject to change from the time and date that you print this page.
6/3/2015 8:03:55 PM. For Customer Service, please call 800.933.9904
Our Princess and the Pea Bedding is like something out of a fairytale. Actually, that's exactly what it is. The quilt depicts a stack of mattresses topped with an adorable princess from the memorable children's story. And a cheerful little pea sits at the bottom. The coordinating sheet sets are a cute multi colored scallop design; made from 100% super soft cotton, so you can rest easy knowing your princess will also rest easy.
Green Leaf Princess & Pea Sham 20"Wx26"H
Details, details
- A Jillian Phillips design
- Quilt is made up of appliquéd prints and detailed embroidery
- Sham is offered in both Pink Multi Polka Dot and Green Leaf
- Quiltiing stitches on shams create a unique circular pattern
- Quilt available in twin and full/queen
- Sheet sets are offered in twin, full and queen
- Complete the look with the Princess and the Pea throw pillow
- Click here to order Complimentary Swatches
Show 'em what you're made of
- Quilt and Sham: Shell is 100% cotton; Fill is 100% polyester
- Sheet Set and Case: 100% cotton and 200 thread-count
Care instructions
- Machine washable
Extras! Extras!
- Don't forget to add our hypo-allergenic Natural Harmony™ comforters and pillows
At The Land of Nod, nothing is more important to us than providing safe, high-quality products to you and your family. We believe that kids' products should be able to handle everything kids throw their way (literally and figuratively). That's why all of our products have an 18-year quality guarantee. And, hopefully, your kids will no longer be sleeping in bunk beds by then.
Who's there?
Ike who?
I can't get in.
Princess and the Pea Sheet Set
Our Designers Recommend
Larkin Metal Bed (Stone) $499.00 - $599.00More Colors Available
Jenny Lind Nightstand (White) $199.00More Colors Available
Princess and the Pea Toddler Bedding $19.97 - $99.97reg. $24.00 - $129.00
Dobby Dot Panels (Green) $24.97 - $39.97reg. $29.00 - $49.00More Colors Available
Top Tier Chandelier $139.00
Ribbon Cutting Rug (Grey) $69.00 - $229.00More Colors Available
Checkmate Table Lamp Base (Grey) $69.00More Colors Available
Polar Bear in a Snowstorm Sheet Set $14.00 - $109.00
Customers Also Viewed
Princess and the Pea Crib Skirt $49.97reg. $59.00
New!Twin Mermaid Mixer Quilt $199.00
Monarch 6 Drawer Dresser $849.00
Brownstone Bookcase $599.00
All That Glitters Goldfish $14.95
Patterned Print Baby Quilt (Pink) $89.00More Colors Available
Sugar Plum Bunny $39.97reg. $79.00
Mythical Edition Plush Unicorns (Set of 3) $29.00More Colors Available
New!4 x 6' Heart to Heart Rug $249.00
Gold Standard Wall Shelf $69.00


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Epworth Post Office
685 Madola Rd, Epworth, GA 30541
Phone: 706-492-3588
Toll-Free: 1-800-Ask-USPS® (275-8777)
Monday-Friday 8:15am - 12:00pm, 1:00pm - 4:30pm
Saturday 8:15am - 12:00pm
Sunday Closed
Monday-Friday 8:00am - 12:00pm, 1:00pm - 4:30pm
Saturday 8:00am - 12:00pm
Sunday Closed
Monday-Sunday 12:01am - 11:59pm
Monday-Sunday 12:01am - 11:59pm
Monday-Saturday 10:00am
Sunday Closed
Monday-Friday 4:15pm
Saturday 12:00pm
Sunday Closed
Monday-Friday 8:00am - 12:00pm, 1:00pm - 4:30pm
Saturday 8:00am - 12:00pm
Sunday Closed
*This facility is not a US Passport renewal office. Check nearby locations below to apply for or renew your passport.
*Please call to verify all information
- General Delivery
- Money Orders (Domestic)
- Money Orders (Inquiry)
- Pickup Accountable Mail
- Pickup Hold Mail
- PO Box Online
Visit our Links Page for information pertaining to Change of Address, Hold Mail/Stop Delivery, PO Boxes™ rentals and fees, Rates on Postage Stamps and Freight/Shipping, Holidays, Bulk Mail, Money Orders, and Available Jobs for Employment in a new post office career.
*Is any of the above information incorrect? Let us know here
Nearby Post Offices:
Mc Caysville
175 Blue Ridge Dr
1.5 miles away
145 Ocoee St
1.6 miles away
1656 N Highway 68
3.4 miles away
Blue Ridge
273 Orvin Lance Dr
4.6 miles away
Click Here for Larger Map - *Please call to verify location


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I predict that all (or most all) of the federally facilitated exchange states will quickly adopt a state exchange, making the court's decision moot.
The Supreme Court will hear arguments in the King v. Burwell case today. The case challenges the legality of tax credits made available in the 2010 Affordable Care Act.
Rick Bell and I will live blog throughout the day on March 4 on the Supreme Court hearings on constitutionality of the individual premium subsidies of the Affordable Care Act.
Leave the political arguments of the ACA to the glib pundits and analysts; we sought out people on the ground floor, those who have to make it work, whatever their feelings about the law or its political symbolism.
It's hard to believe that five years have since passed, with the ACA surviving charges of death panels, chair-tossing town-hall sessions, more than 40 repeal votes and a major Supreme Court challenge.


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To beer, or not to beer? 'Can ban' slows tourism
As far as trash and rowdiness go, can ban backers are already claiming victory. City data show that 1,800 pounds of litter was collected in and around the river in May - about 15 percent of the amount that had to be cleaned up in May last year.
Other unruly behavior also seems to be on the downturn. New Braunfels police Capt. Michael Penshorn said that on a recent June weekend, police patrolling the river issued 26 citations and arrested four people on charges ranging from minors in possession to public intoxication. On the same weekend last year, police wrote 42 citations and made 17 arrests.
Mike Kubelka, 50, patted his wet bathing suit with a towel before driving back to College Station with his two kids after they practically had the whole Guadelupe to themselves on a slow Monday. Now that he's a parent, Kubelka said, he doesn't mind seeing less beer on the river.
"But," he said, "it gets kind of long out there with nothing to drink."
Follow Paul J. Weber on Twitter: www.twitter.com/pauljweber
The Associated Press


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Jylle Navarro Fall/Winter 2013 collection is heavily inspired by a space age/ futuristic/ alien theme.#10170
Beautifully packaged, natural straight razor whetstones from Zulu Grey. A South African hone company helping to bring back the fine art of Straight Razor shaving...#10165
BELLE NOIR ~ Amazing comfortable jewelry made of recycled silicone baking molds.#10164
Chic flat lace-up sandals by designer P.Monjo. Made on the island of Mallorca, Spain.#10159
Selvage white floral discharge print from The Hill-Side. Original fabric from Okayama, Japan.#10154
Supreme x The North Face 2013
Supreme and The North Face release their upcoming collection as part of their longstanding relationship.
The perfect bag: rugged twill from Filson and Nanamica, with four roomy full-length interior sections.#10144
This Weekend bag from Carga is made of industrial grade canvas. The collection, which includes two other models, has detachable straps making it easy to wash.#10140
Feeling foxy? Gentlemen, dress up your outfit with a printed silk pocket square by Daniel Bruce, that will have you looking as slick as a fox. This pocket square is 100% silk and made in Italy.#10136
The search for a system that causes a bag fold entirely flat has resulted in this amazing geometric shape. By dutch designer FRRRY.#10130
From We Dream in Colour, this brass cuff features exceptional verdigris detailing.#10129


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Earth Day is a great day to volunteer for wildlands, and to start planning volunteer activities to help public lands throughout spring, summer and fall.
Habitat restoration and trail maintenance projects require considerable labor, and volunteers are critical to keeping our shared places safe and accessible to visitors and native species alike.
Our connections with nature may not only determine our happiness but also our attitudes about protecting the environment, according to new studies.
We know that Earth Day isn't the only day of the year to show our passion for wilderness.
This week is National Environmental Education Week, April 13-19, 2014. It is a week to celebrate the connection between young people and the outdoors.
One place we're doing that is in Montana's Southwestern Crown of the Continent.
For the vast Sierra Nevada, it's more important than ever to see the forest for the trees.
I am swinging a pulaski deep into the ground, hoping to chip off a nice large chunk of soil. I am on Sampson Mountain on the eve of the 25th anniversary of the Tennessee Wilderness Act of 1986, doing trail maintenance in this magnificent wilderness.
Last Saturday I was able to join 30 enthusiastic hikers to explore a kind of wilderness that is different than what we often think of as "wilderness" – the subtle, enigmatic hills and valleys of the Adobe Badlands.


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LAGRANGE, Ohio
John Dwight Andrews Jr., 70, of LaGrange, died Monday, June 9, 2008, in EMH Regional Medical Center after a short illness.
He was born Nov. 3, 1937, in Wooster, Ohio. He was a 1957 graduate of Elyria High School and served with the U.S. Army from 1962-1964.
John was employed as a Project Superintendent in the construction industry throughout Ohio and the Midwest, retiring in 2002. He was a member of The First Church in Oberlin, United Church of Christ and Carpenter's Union Local No. 305, Norwalk. He enjoyed golf, all sports, horses and working with his hands.
John is survived by his wife of 43 years, Lenore M. (Anthony); and daughter, Christa M. Andrews of LaGrange.
He was preceded in death by his parents, John Sr. and Lucille J. (Weiker) Andrews, both in 1999; sisters Marilyn Loper in 2002, and Jeannette Keim in 2003.
A graveside service will be 9:30 a.m. Friday in Ridge Hill Memorial Park, Amherst Township, followed by a memorial service at 11 a.m. in The First Church in Oberlin, United Church of Christ, 106 N. Main St., Oberlin, OH 44074; the Rev. David T. Hill, pastor, will officiate. Dicken Funeral Home and Cremation Service, Elyria, is handling arrangements.
In lieu of flowers, memorial contributions may be made to the church.


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F800GS Snatchy Throttle Fixed!
View Single Post
Gnarly Adventurer
Joined: Jun 2011
Location: District 37
Oddometer: 126
+1 for the G2
Installed the G2 on Thursday night (huge props to YetiGS for the pictorial and the beginning of this thread, it was a major help
) and was able to take it out for a proper test ride this weekend.
I could not be happier with the results!! A booster plug was one of the first mods I did for the GS, and while I was pleased it still never felt like how i thought it should. It was still very "snatchy" or "lurchy" in the slow technical stuff. The product description made sense and with the exception of the scotts steering stabilizer it's been the best upgrade hands down. (Side note: I recently switched to the off road version of the stabilizer from the on-raod version; that too has made a world of difference as far as fatigue and control). It got down to around 40 degrees so i was able to give the heated grips a little function test and there was a little less noticeable heat from the right grip but hardly enough to complain for the added benefit from the G2. In fact, probably run the G2 with handguards and no heated grips if those were my only options.
So specifically what I like: I no longer need to use the clutch so often to ensure smooth power deliver (for both traction and comfort) at low speeds. It makes such a difference to be able to be on the throttle and able to provide minute throttle inputs whereas before it felt like almost an on/off switch. Best bang for the buck mod I've made, a no-brainer for $80 if you ask me.
View Public Profile
Find More Posts by officerleroy


text: Therapeutic essential oils in their purest form with all your favorites like peppermint, lavender, and sandalwood for starters. We offer a broad spectrum of single essential oils in a variety of sizes. All at 10% off retail. Consider buying oils in bulk and get 30-59% off! Check out our wholesale essential oil pricing and information.


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|Major League Baseball
· News
· Current Odds
· Gaming Matchups
· Live Odds
· Pitching Report Cards
· Probable Pitchers
· Scoreboard
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· Teams Index
· Transactions
· Weather
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American League
· Injuries
· Power Poll
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· Schedule
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National League
· Injuries
· Power Poll
· Previews
· Recaps
· Rotations
· Schedule
· Standings
· Statistics
American League Preview from The Sports Network
Wednesday, September 18th (All times Eastern)
Texas Rangers (82-68) at Tampa Bay Rays (82-68), 7:10 p.m.
Probable Starting Pitchers: Texas - Derek Holland (9-9, 3.49) Tampa Bay - Chris Archer (9-7, 3.03)
(Sports Network) - The Texas Rangers try to make it two straight wins on Wednesday when they continue a four-game series with the Tampa Bay Rays at Tropicana Field.
Texas ended its season-worst seven-game losing streak on Tuesday, as Ian Kinsler and Elvis Andrus each had three RBI to help the Rangers to a 7-1 win. Kinsler homered to begin the game and Andrus went deep during a four-run third for Texas, which won for only the second time in its last 12 games and pulled into a tie atop the wild card standings with the Rays.
"Given the circumstances, it was a big win. We're gonna try to build off it as best we can," Kinsler said.
Alexi Ogando (7-4), making his first start for Texas since Aug. 13, limited the Rays to two hits, one being a Jose Lobaton homer, in five innings of work.
Starter Jeremy Hellickson (11-9) lasted just 2 2/3 innings in his outing for Tampa Bay.
The Rays and Rangers are a half-game up on Cleveland in the playoff race.
"I just didn't start off right. I settled down a little bit, and in the third walked the leadoff guy and you can't do that against a lineup like that," Hellickson said.
Getting the call for Texas on Wednesday is lefty Derek Holland, who has lost his last three starts and is winless in his last seven. Holland was roughed up badly by the Oakland Athletics on Friday, as he surrendered six runs in three innings to drop him to 9-9, while raising his ERA to 3.49.
"Despite what happened in the Oakland game, I still saw a lot of positives," Holland said. "My bullpens since then have been great, getting my mechanics in shape, finishing my pitches and hitting my spots. It just seems like I wasn't getting all the way through the ball."
Holland is 4-3 in nine starts versus the Rays with a 4.92 ERA.
Tampa, meanwhile, will counter with rookie Chris Archer, who was terrific in beating Minnesota on Friday. Archer scattered three hits over six scoreless innings to run his record to 9-7 to go along with a 3.03 ERA.
Archer did not get a decision in his only other meeting with the Rangers.
Texas has won three of five matchups with the Rays this season.


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Charting the Map of Life.
When scientists announced they had mapped a rough draft of the human genome--identified 85-90% of the ordered sequence of DNA on each chromosome--the event was lauded around the world as the greatest scientific achievement since the Apollo 11 moon landing. Some scientists called the accomplishment nothing less than the beginning of a true understanding of biology. At a 27 June 2000 White House ceremony featuring the heads of the two teams responsible for the feat--J. Craig Venter, president and chief scientific officer of the Rockville, Maryland-based Celera Genomics, a privately funded biotechnology company, and Francis S. Collins, director of the publicly funded National Human Genome Research Institute--President Clinton said, "Today we are learning the language in which God created life."
The map of the human genome points to a vast uncharted territory, much of it a wasteland. Only 3-5% of the genome--corresponding to between 30,000 and 100,000 functional genes--is thought to be biologically functional. The remainder is so-called junk DNA that may someday be shown to have biologic merit, but that for now is largely seen as filler that remains in the genome for unknown reasons. Scientists expect that mapping the genome will lead to a host of innovations in biology and research. For example, DNA microarrays, devices that analyze the level of expression of thousands of genes at a time, could be used to accurately diagnose cancer and infectious disease subtypes and to predict clinical outcomes. Scientists will also use the genome to look at the interactions of the environment, genetic makeup, and toxic exposures, including the ability of certain genes to detoxify the body and promote disease resistance.
The genome will provide tremendous resources for understanding human diversity and evolution. All humans on the planet are roughly 99.9% genomically identical, not surprising considering a common ancestry thought to date back 150,000 years to a tiny band of people in Africa. Within the remaining 0.1% of the genome are the 3 million letters of DNA that govern our physical differences. Many portions of the human genome, particularly those coding for metabolic processes, are identical to those of other species. Comparative genomics studies will provide insight into how metabolic and other physiologic systems evolved in different species.
But despite the great potential of genomics, scientists caution that public expectations need to be tempered with reality. Decrying what she calls the "media inflation of genetic technology," Lily Kay, an associate of the museum of comparative zoology at Harvard University in Cambridge and author of Who Wrote the Book of Life? A History of the Genetic Code, says, "We are bombarded daily by media reports of the genetic revolution. And the usual approach is to absorb uncritically these scientific forecasts as fait accompli." The fact is, she says, people are as much a product of their environment as they are of their genes. And to suggest that genetics is the sole determinant that defines us as individuals, writes Eric Lander, director of the Whitehead Center for Genome Research in Cambridge, in a 12 June 2000 editorial in The New York Times, "stretches the science far beyond the data."
The Nuts and Bolts
Mapping the human genome is the most recent event in a genetic time line dating back to Gregor Mendel, who discovered the basic principles of heredity in the mid-1800s. Mendel introduced the concept of the gene as a unit of information through which hereditary information is passed from one generation to the next. Later, the concept became less abstract with the discovery that genes are made of the substance DNA. The three-dimensional structure of DNA and its method of replication was discovered by James Watson, an American postdoctoral fellow, and British graduate student Francis Crick at Cambridge University in England. In their classic paper titled "Molecular Structure of Nucleic Acids. A Structure for Deoxyribose Nucleic Acid," published in Nature in 1953, the two scientists described the double-helical form of the molecule, shaped like a twisted ladder, in which each rung is made up of four nucleotides: adenine, thymine, cytosine, and guanine (typically abbreviated as A, T, C, and G). The nucleotides are arranged in a series of base pairs, in which A bonds with T, and C with G. In the years that followed, researchers discovered that genes code for amino acid sequences, which themselves comprise the proteins that make life possible.
A genome map is essentially a representation of where genes are located on the chromosome. At the coarsest level of resolution are genetic linkage maps, which describe gene locations based on their patterns of inheritance, for instance as observed in mating experiments with Drosophila melanogaster (fruit fly). The first such map was developed in 1913 by Alfred Sturtevant while he was an undergraduate in zoology at New York's Columbia University. Working with embryologist Thomas Hunt Morgan in the legendary "fly room" at Columbia, Sturtevant arranged the ordered sequence of genes for eye color, wing shape, body size, and other characteristics based on their appearance in consecutive generations of Drosophila. Morgan himself was the first to associate a specific gene with a specific chromosome; again experimenting with fruit flies, Morgan found that the mutant gene for white eyes (most fruit flies have red eyes) is found only in male progeny and is located exclusively on the X chromosome--a discovery for which he won the Nobel Prize for Medicine in 1933.
Gene mapping (and indeed, the whole field of molecular biology) hit its stride in the late 1960s with the discovery that restriction enzymes could be used to cut DNA into specific sequences. In nature, restriction enzymes protect bacteria by slicing up invading viral DNA. But in the laboratory, they can be used as molecular "scissors" that recognize a highly specific DNA sequence, or type of sequence, and then cut the DNA at the same site in the sequence. Over 3,000 restriction enzymes have been identified to date, affording scientists great specificity when chopping DNA into isolated fragments. The fragments can be cloned (usually in bacteria) or duplicated using a variety of biochemical techniques to provide the unlimited genetic material needed for experimental studies.
These techniques have been used to generate higher-resolution physical maps that describe the biochemical structure of DNA and the ordered sequence of the genes themselves. By the early 1990s, scientists were constructing physical maps of model organisms using a procedure called map-based sequencing. The process involves cutting DNA into fragments of about 200,000 base pairs called bacterial artificial chromosomes (BACs), taking note to record the position of the BACs on the genome, cloning the BACs in bacteria (such as Escherichia coli), determining the sequence of the base pairs, and then reassembling the BACs in their original order using a computer.
Map-based sequencing is the technique of choice for the Human Genome Project (HGP), a consortium of research centers funded by the National Institutes of Health, the U.S. Department of Energy, and the Wellcome Trust, a medical philanthropy based in London. The HGP was formed in 1990, with the goal of mapping the human genome by 2005, a date shortened by five years by politics, competition, and a variety of technical innovations. In addition to mapping the human genome, the project aims to store the information in databases, address the ethical, legal, and social issues raised by the project, and develop tools for data analysis and better sequencing technologies.
Scientists had still not completed a genome map for any organism by 1994, the year Venter and Nobel Prize-winning molecular biologist Hamilton O. Smith proposed speeding up the process with an alternative method they called whole-genome shotgun sequencing. In contrast to the HGP's method, in which the order of the BACs is known before they are each sequenced individually and then reassembled, the shotgun method involves cutting the DNA into small, random, overlapping pieces that are then sequenced and reassembled using a computer that compares all the pieces and matches the overlaps, thus assembling the whole genome. In 1995, with this technique, Venter and Smith mapped the genome of the disease-causing bacterium Haemophilus influenzae--the first completed genome of any single organism.
The period from 1995 to 2000 gave rise to a stunning series of technologic advancements, including computer automation and robotics, that accelerated the rate of genome mapping. At the forefront was a machine called the ABI Prism 3700 DNA Analyzer, introduced in 1998 by the Perkin-Elmer Corporation. This machine is involved in the last step of the sequencing pipeline. Its job is to separate fluorescently labeled DNA fragments by size to determine the sequence of nucleotide bases found on a strand of DNA. Now used by major DNA sequencing laboratories around the world, the Prism 3700 increased the rate of genome sequencing by approximately 20-fold.
The equipment used by both Celera and the HGP to draft the map of the human genome was virtually identical. The only difference between the two organizations was their basic methodology: the HGP used map-based sequencing while Celera used shotgun sequencing. The physical map they produced, the "language in which God created life," is an eye-numbing series of As, Ts, Cs, and Gs stretching into the billions.
Scientists acknowledge that much work on the human genome remains to be done. Since announcing the completion of the rough draft in June, Celera has moved on to other more lucrative pursuits befitting a biotechnology company, such as identifying and patenting gene sequences. Meanwhile, the HGP advances toward a final map, expected to be completed by 2003. At the present time, the BACs covering the two smallest chromosomes, numbers 21 and 22, are essentially complete. Chromosome 22 is particularly noteworthy: it's packed with over 545 known genes (at least 300 more are suspected) ranging in size from 1,000 to 583,000 bases of DNA. Gene variations on chromosome 22 are thought to be associated with at least 27 human disorders including brain cancers, schizophrenia, and multiple birth defects. Other BACs on other chromosomes are still in various states of disassembly, and there are still significant gaps to be filled. Nevertheless, the working draft is considered to be of great value for researchers looking for genes, and it represents a major accomplishment. Says Collins, "The completion of the human genome sequence will have a profound effect on understanding genetic contributions to human disease and the development of strategies for minimizing and preventing disease altogether."
Gene-Environment Interactions
One of the most exciting applications for genomics is in the area of gene-environment interactions. Now light-years beyond the theories of evil spirits and "bad blood" espoused by our ancestors, modern science views illness as the outcome of three related factors: genetics, environmental exposures, and aging. Like death and taxes, aging is a certainty. But within the complex interplay of genes and the environment lies a range of potential targets for disease prevention and treatment--particularly for cancer, pulmonary diseases, neurodegenerative disorders, developmental disorders, birth defects, reproductive function, and autoimmune diseases, all of which have been shown to be influenced by environmental agents. In fact, in a paper published in the 13 July 2000 issue of the New England Journal of Medicine, Paul Lichtenstein of the Karolinska Institute in Stockholm, Sweden, and colleagues state, "Inherited genetic factors make a minor contribution to susceptibility to most types of [cancers]. This finding indicates that the environment has the principal role in causing sporadic cancer."
One group spearheading the effort to elucidate gene-environment interactions is the Environmental Genome Project (EGP), headquartered at the NIEHS. Maynard Olson, director of the University of Washington Genome Center in Seattle, where much EGP research is conducted, describes gene mapping as an "extremely powerful tool for furthering investigations into human biology and its interactions with the environment." Many of the enzymes and proteins involved in toxicity have already been identified in classical cell biology studies, he says. What genomic information allows researchers to do is build on this knowledge by identifying how many types of these proteins are expressed, and in what specific tissues they are found.
The mission of the EGP is to identify genes already mapped by other programs (the organization is continually soliciting candidate genes), and then to resequence the genes in an exhaustive search for the variations that augment resistance or susceptibility to environmental exposures. Most variants of interest are called single nucleotide polymorphisms, or SNPs, which are genes whose ordered DNA sequence is mixed up in ways that alter protein expression. If these proteins are involved in metabolizing or detoxifying chemical agents, it's likely that exposure will cause greater harm. For example, a protein called p53 participates in cell signaling processes related to DNA repair, which is important because DNA is continually bombarded by carcinogens from inside and outside the body. If p53 detects chromosomal damage, it signals the cell to stop DNA synthesis or even undergo cell death. A person with a genetically inherited mutation that alters the function of the p53 gene may be highly susceptible to cancer. Not surprisingly, the EGP has focused its initial efforts largely on finding SNPs among genes that, like p53, participate in DNA repair. Other processes of interest include cell cycle control, xenobiotic metabolism, and immune and inflammatory reactions.
The most recent addition to environmental genomics at the NIEHS is a newly formed National Center for Toxicogenomics, announced in December 2000 [see NIEHS News, p. A22]. Jose Velazquez, a program administrator for the NIEHS Division of Extramural Research and Training, says the center will complement the activities of the EGP by investigating patterns of gene expression and protein function in response to chemicals. "It's not enough just to understand the expression of the gene," he says. "You also have to understand the function of the protein." The problem is that protein function--particularly in the context of environmental exposure--is extremely difficult to characterize. The way the genome reacts to chemicals is highly dependent on timing and dose. Either of these parameters can exert a major influence on gene expression. Furthermore, chemicals trigger biochemical cascades within cells in which some proteins are turned off, others are turned on, and some aren't affected at all. It's really more a question of genome expression than gene expression. And indeed, many genomic scientists say the key to the future of genomics is actually found in functional genomics, or proteomics, which seeks to understand the global activity of proteins in a cell at any given time. Understanding how all the pieces fit together is as much a computational challenge as it is a biochemical mystery. For this reason, the center has also proposed the improvement of mathematical paradigms for the study of protein function as a major agenda item for the future.
The EGP's ultimate goal is to sponsor and support epidemiologic studies of gene-environment interactions, both at the NIEHS and by outside researchers funded through the institute's extramural grants program. Empowered by databases with useful information about genes and gene functions, researchers in the genomic era will be able to more clearly determine how specific populations respond to their environment. The activities now under way at the EGP constitute a critical step in that direction.
Comparative Genomics
Although the public's attention has been captured by human genomics, mapping and studying the genomes of other organisms--or comparative genomics--is also important. Jonathan King, a professor of molecular biology at the Massachusetts Institute of Technology in Cambridge and a board member of the Council for Responsible Genetics, says, "Most genes evolved long ago, and there is enormous homology for essential functions like metabolism." Therefore, he says, the amino acid sequences of many proteins are identical throughout all the higher species, a phenomenon known as genetic conservation. Comparative genomics is generally undertaken for two reasons: to provide road maps that help researchers locate genes for inherited characteristics and behavior in humans and other creatures, and to advance the study of genomic evolution. As the maps become available, blocks of human DNA will be compared to other species to understand not only sequencing gaps but also genetic conservation. To date, physical maps of yeast, the soil worm Caenorhabditis elegans, and the fruit fly (in addition to numerous bacteria and viruses) have been completed. Scientists are also mapping the genomes of the mouse, rat, cat, dog, pig, cow, goat, zebrafish, rainbow trout, tilapia fish, medaka fish, rabbit, chicken, sheep, and horse.
Researchers at the Laboratory of Genomic Diversity (LGD) at the National Cancer Institute's Frederick Cancer Research and Development Center in Frederick, Maryland, are mapping the cat genome, which apparently shares more order homology (meaning similar order of genes on the chromosome) with the human than any other nonprimate species that has been studied. According to William Murphy, a geneticist with the LGD, this means that genomes of both cats and humans have changed relatively little during the 90 million years since mammals diverged from their parent ancestor. Comparing the genome to a deck of cards, he says the genes of other laboratory species including mice, rats, and dogs have been substantially reshuffled over time, making them more challenging than the cat for studying genomic evolutionary history.
Comparative genomics is also useful for identifying models of human hereditary disease. There are a multitude of genetic diseases that show up in humans and other animals. Cats, for example, carry genes for hemophilia, polycystic kidney disease, and hypertrophic cardiomyopathy. According to an article by Stephen J. O'Brien and colleagues from the LGD published in the 15 October 1999 issue of Science, nearly every human gene has a mouse homologue, making this traditional laboratory animal highly amenable to the study of genetic illnesses. Studies in mice have already identified mutated genes for multiple disorders that are also present in humans. In the best known example, a mutated gene involved in metabolism is present in both overweight mice and morbidly obese humans. Similarly, comparative mapping studies of hypertension in rats have uncovered candidate genes for the same disease in humans. Within the year, scientists with the HGP expect to complete working drafts of the mouse and rat genomes, which will expand the potential for comparative inference relating to human health. As this occurs, scientists will use rodent models, and those of other species as well, to identify candidate genes for analogous functions in humans and to define their interactions with other genes in the context of mutation, environmental exposure, infectious disease, sex, aging, and more.
The Myth of Determinism
Ironically, even as gene-environment interactions grow in scientific prominence, scientists worry that the recent media hype is helping to resurrect an outdated theory of "genetic determinism," which suggests that individual phenotypes are governed wholly by genetic makeup. The danger, they say, is that people will take a fatalistic attitude toward disease and discount the effects of environment and lifestyle. David Page, chair of the Whitehead Task Force on Genetics and Public Policy and a professor of biology at the Massachusetts Institute of Technology, attributes the problem to a tendency among scientists to simplify genomics for the press, which have adopted "Gene X Causes Disease Y" as their standard headline. Without efforts to dispel some of the fuzziness surrounding genetic mechanisms, he says, the public will believe the truth is as simple as the headlines would suggest.
And just as the genome isn't deterministic in the context of the entire organism, neither is it deterministic with respect to the structure of individual proteins. Knowledge of the genome makes it possible to describe a protein's amino acid sequence, but not to predict its three-dimensional shape. A host of internal factors within the cell contribute to protein "folding," which governs the protein's receptor chemistry and therefore all of its functionality. This is a major problem for biotechnology and pharmaceutical companies hoping to use genomics to create new classes of drugs--a fact that is rarely appreciated by the public. "This is why gene-based biotechnology is in trouble," says Kay. "Gene-based biotechnology lost $5 billion last year. One hundred seventy-six drugs were proposed; one was approved, and the others faltered in the second stage of clinical trials."
Ultimately, some suggest, genomics will be more useful as a research and diagnostic tool than as an agent that lifts medical treatment to new heights. However, efforts to use genomics for these purposes are increasingly hamstrung by a new application for the law in biology: gene patents and intellectual property protection for gene products [see Spheres of Influence]. Private-sector companies are increasingly patenting gene sequences, cell lines, genetically modified organisms, and even natural species--a practice that has angered many prominent scientists. Leveling sharp criticism at what he calls a "radical extension of patent law," King says, "Genes are the products of millions of years of evolution and are in the deepest sense products of nature. They are not the inventions of individuals, corporations, or institutions." King predicts that gene patents will retard research because investigators won't share information for fear of undermining the ability to file patents later, and will impede health care delivery because providers will need to pay licensing fees to use gene products. In addition, he says, such patents provide a legal mechanism for companies to charge excessive sums for genetic screening (in the event they own the patent to the gene sequences of interest to the patient) and even more for gene therapy (in the event the screen shows the patient's own gene is defective).
But, illustrating the contentious nature of the debate, these concerns were rejected by Philip Reilly, the chairman of the board and chief executive officer of Interleukin Genetics, a biotechnology company located in Waltham, Massachusetts. Reilly says that without legal protection for intellectual property, the $20 billion in research dollars spent annually by biotechnology and pharmaceutical companies would dry up overnight. "I'm the CEO of a very small biotech company," he says, "and I have never seen a more Darwinian process than trying to bring a biotech product forward. The vast majority of these companies fail, and the return on investment is very low." He also charges that it is false to assume that biotechnology companies are looking to establish a "captive population for gene therapy." Responding to negative publicity following the September 1999 death of 18-year-old Jesse Gelsinger, who died following experimental gene therapy for a rare metabolic disorder, he says, "Venture capital companies are running scared from gene therapy."
And so, even as genomics promises to play a vital role in the future of biologic research, the overriding question facing society is how to use the information in ways that benefit the common good. Clearly, the answers to these questions remain unknown. What seems apparent is that genomics must be placed in the context of the whole human experience, including the environment in which we live. "Poverty is the main source of disease in the world," says Olson. "It's not genetic variation [that degrades public health] as much as it is economic variation. And we shouldn't forget that."
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L8 Nite Thursdays: Dozens of retail stores in downtown Encinitas will stay open until 8 p.m. on Dec. 23, with refreshments 5 to 8 p.m. at participating stores. Santa Claus is at The Lumberyard Plaza on L8 Nite Thursdays 5:30-7:30 p.m. Sponsored by Downtown Encinitas MainStreet Association. (760) 943-1950.
Santa at Sunset: Santa Claus will visit Oceanside's Sunset Market near Dorothy's Kidzone 5:30 to 7 p.m. Dec. 23. The market is at Tremont Street between Mission Avenue and Civic Center Drive; Pier View Way between Coast Highway and N. Cleveland Street. Pony rides, bounce house and holiday gift fair. www.sunsetmarketoceanside.com.
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Christmas Eve Farmers Market: Vista Farmer's Market normally runs 8 a.m. to noon on Saturdays, except the Dec. 25 market will be moved to Friday Dec. 24 with fresh produce and a Christmas Market featuring live music by Coco & Lafe. The Vista Farmers Market is at the County Courthouse parking lot, 325 South Melrose Drive. The market will be back on Saturday schedule Jan. 1. (760) 945-7425
Del Mar Holidays: Free live music each Friday except Christmas Eve 5 to 7 p.m. including New Year's Eve at the Del Mar Plaza Deck on Camino Del Mar at 15th Street. Peter Sprague Jazz Concert 1 to 4 p.m. Dec. 24 at L'Auberge Del Mar Amphitheater. Hot Chocolate and cookies. www.delmarmainstreet.com.
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Christmas Dinner: Seaside Center for Spiritual Living sponsors its seventh annual Christmas dinner potluck noon on Christmas Day, Dec. 25, at 1613 Lake Drive in Encinitas next to the Cardiff Sports Park. Those who can bring dishes are asked to bring a little extra for those who cannot. Volunteers needed. (760) 633-0122.
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To ride ing around town on ur atv or truck to messing around at home a suvivel tin is just what u need
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Don't look now but the Reds are up to 6th in team batting average, and up to 10th in runs scored in the NL. And they are positive by +4 in runs scored vs. runs allowed (when's the last time we could say that?)
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- Coagulation Disorders (incl. Hemophilia)
- Colorectal Cancer
- Deep Vein Thrombosis (DVT)
- Hypercoagulable State
- Liver Cancer
- Lung Cancer
- Lung Neoplasms, Not Specified as Malignant
- Macroglobulinemia (incl. Waldenstrom's )
- Meningiomas
- Myelodysplastic Syndromes
- Myeloma
- Myeloproliferative Disorders
- Neuroendocrine Tumors
- Non-Hodgkin's Lymphoma
- Pancreatic Cancer
- Polycythemia Rubra Vera
- Prostate Cancer
- Secondary Malignancies
- Soft Tissue Sarcoma
- Thrombocytosis
- Venous Embolism and Thrombosis
Background Check for Dr. Kral
0 Malpractice Claims
- No malpractice history found for California.
- No sanctions history found for the years that Healthgrades collects data.
0 Board Actions
- No board actions found for the years that Healthgrades collects data.
Education & Training
Medical School
- Keck School Of Medicine Of The Univ Of Southern California
- Graduated in 1990
Internship Hospital
- University Of California Los Angeles School Of Medicine
Residency Hospital
- University Of California Los Angeles School Of Medicine
Fellowship Hospital
- University Of California Los Angeles School Of Medicine
- University Of Southern California School Of Medicine
Languages Spoken by Dr. Kral & Staff
- English


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Tips for Trips: Advice from a Haitian Missionary
by Jillian Kittrell ('08), Emmaus House, Cap Haitien, Haiti
As a host of short-term mission teams, I often get asked whether or not I validate the money spent on their mission trip. I dread this question.
I mean, what in the world do they expect me to say? For most teams my answer is an absolute yes, however sometimes, if I were to be completely honest, I might just say I wish they had stayed home and sent us their money instead.
Truth is, I don't know how I really feel about this question. As a previous short-term missionary, I know how good short-term missions can be. Coming to Haiti every summer was my favorite part of the year. The relationships I built with people during my short-term visits were priceless and eventually brought me to Haiti to live and serve full time. I am a huge supporter of short-term missions. But on the flip side, now that I am the one living here and receiving teams, I can't help but to let my mind wonder into the "what ifs".
What if teams stopped coming for just one year and sent us their money instead?
What if we had $100,000+ extra dollars to work with instead of teams?
My mind begins to spin around with the possibilities.
We could remodel our facilities, hire new employees, increase staff salaries, pay off some debt, send a few students to college, feed countless people in our community, and the list goes on…
Maybe that sounds awful, but that is honestly where my mind goes sometimes.
Please don't think I am saying I think all of our short-term mission teams should just stay home and send us money. Please don't think that at all. All I am trying to say is this: If you are going to invest a large amount of money in a short-term mission, make your time and money worth it.
First of all, don't go somewhere to do what missionaries and the local people can already do for ourselves. Instead, come for something greater. Do your research on what we can't provide and do ourselves, and come do that. Second, come to encourage the Christians who are already working hard to spread the kingdom of God in a given area. Third, come to learn. And above all, come to build relationships with the local people.
I have been fortunate to play many different roles in short-term missions- first as a participant, then as a team leader through Lipscomb, and now as a host here in Haiti. All three roles have taught me countless lessons about short-term missions. Being a host for the past 2½ years, however, has afforded me more wisdom than I have ever expected to receive on the topic.
Am I a supporter of short-term missions? Absolutely! If it weren't for short-term missions I wouldn't be living here in Haiti today. Short-term missions has changed my life. And I believe it can change everyone's life if they let it. That may not mean moving oversees for everyone, but for some it may. How missions should change each one of us should be up for God to decide.
Last but not least, remember that Jesus told us to go to make disciples (Matthew 28:19). He didn't tell us to go paint, play, build, or heal. These things, although good, are not the reason why you should go on a mission trip. You go on mission trips to bring others to Christ. If you are a doctor going to help people's physical pains, do so with the underlying cause of planting seeds in your patients. If you are going to build a building, do so with the intention to plant seeds with the locals you will be working with. And the list goes on.
All in all, I love short-term missions. In the grand scheme of things they are a glimpse into our future in Heaven- a future when all nations will gather together to bring glory to God. Forget culture, country, and language barriers- we will all be one. So if you participate in short-term missions in any capacity, I thank you for your willingness to love and help others all over God's beautiful world. May you be a blessing to those you have been called to serve.
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Lipscomb Missions
One University Park Drive Nashville, Tennessee 37204 | firstname.lastname@example.com | 615.966.6049 | Ezell 238


text: NC Senate sees lawmaking continue into November By: The Associated Press July 31, 2014 RALEIGH— North Carolina lawmakers want to continue their election-year legislative session past November's elections. A Senate committee unveiled legislation Thursday that would adjourn their annual session Saturday, then return in less than two weeks to consider overriding any bills Gov. Pat McCrory vetoes. That would give McCrory 10 days to decide on legislation, not the 30 days allowed after ... Subscribe Login Email Address: Password: Already a paid subscriber but not registered for online access yet? For instructions on how to get premium web access, click here.Forgot your password? Share this:EmailPrintFacebookLinkedInTwitterGoogle +1Like this:Like Loading... North Carolina lawmakers session 11:24 am Thu, July 31, 2014 Mecklenburg Times: News for Mecklenburg, Union and Iredell counties The Associated Press


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May 22, 2012
These watermelon Jello shots from That's So Michelle are fun summertime shooters. Different flavored gelatins are mixed with tequila (you can omit the alcohol if you want to serve to children or non-drinkers) are layered upon one another to resemble a watermelon. The green layer is made with lime Jello, the white layer is made by mixing sweetened condensed milk with powdered gelatin, and the final red layer is watermelon flavored Jello. These watermelon shooters are sure to be a hit at your next pool party. For full recipe instructions, click here.
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Correcting Problems With Your Retirement Plan
FCPA Compliance and Ethics Report-Episode 63-Managing the Third Party Relationship Under the FCPA, Part I
Thomson Reuters Session 2: Investment Management, Hedge Funds and Registered Mutual Funds: What's Happening Now?
Did the IRS Just Help or Hurt the Bitcoin Economy?
Tax Traps of Employment Documents
BB&K's Isabel Safie Discusses the Implications of IRS' Definition of Governmental Plan Status
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Hot Topics for Waste-to-Energy Investors and Developers
On Thursday, March 12, 2015, the District of Columbia Department of Employment Services ("DOES") hosted its first Webinar regarding the D.C. Wage Theft Prevention Amendment Act (the "Act"), and its subsequent amendments. ...more
Given the complexity of the rules under Section 409A of the Internal Revenue Code, which govern the timing and taxation of payments made under non-qualified deferred compensation arrangements (NDCAs), companies are encouraged...more
U.S. authorities continue to aggressively pursue cross-border investigations and to scrutinize closely the compliance programs of multinational corporations. Investigative activity by U.S. authorities in 2014 was particularly...more
As of July 1, 2014, the Internal Revenue Service (IRS) has implemented several changes to the streamlined filing procedures for offshore compliance, as well as the Offshore Voluntary Disclosure Program (OVDP). These programs...more
Issuers, underwriters and advisors in the municipal bond marketplace are facing unprecedented challenges from federal regulators in connection with both the issuance of bonds and ongoing post-issuance compliance. These...more
The Treasury Inspector General for Tax Administration (TIGTA) released its annual report on IRS compliance trends yesterday. The key takeaway from the report is TIGTA's finding that the total amount of revenue received and...more
With two seemingly simple and straightforward definitions in the final regulations implementing the Affordable Care Act's pay-or-play rules—i.e., definitions of "employer" and "employee"— the Treasury Department and IRS have...more
On June 18, 2014 the IRS announced changes to the Offshore Voluntary Disclosure Program (OVDP). The changes include the following...more
While employers sometimes view the Affordable Care Act's employer shared responsibility (or "pay-or-play") rules in isolation, they don't operate that way. Instead, they exist side-by-side with other provisions of the Act. In...more
Recent IRS rulings and a U.S. Tax Court decision continue to lay a solid foundation for captive insurance companies. However, the tax requirements must be strictly followed. Below we provide an update to assist captives in...more
On June 18, 2014, the IRS announced a number of significant changes to its Offshore Voluntary Disclosure Program (OVDP) and 2012 streamlined procedure for nonresidents and the addition of a streamlined procedure for U.S....more
The existing OVDP has been in place since March 2009. The program allows a taxpayer to voluntarily come into compliance with US tax reporting obligations and pay a reduced civil penalty rather than facing either greater...more
The new Streamlined Filing Compliance Procedures (the Streamline Procedures) go into effect July 1, 2014. Under the terms of the procedures some taxpayers will suffer no penalty for failure to timely file FBARs, (in the case...more
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The IRS announced substantial changes to both the Streamlined Filing Compliance Procedures for Non-Resident, Non-Filer Taxpayers and the Offshore Voluntary Disclosure Program (OVDP) on June 18, 2014....more
On Wednesday, June 18, 2014 the Internal Revenue Service announced sweeping changes to its Offshore Voluntary Disclosure Programs, effective Tuesday, July 1, 2014. Some taxpayers are treated much more leniently under expanded...more
On Wednesday, the IRS announced substantial expansions of the 2012 Streamlined Filing Compliance Procedures and the 2012 Offshore Voluntary Disclosure Program (OVDP).
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On June 18, 2014, the Internal Revenue Service (IRS) announced major changes to its 2012 Offshore Voluntary Disclosure Program (OVDP) and streamlined procedures. The modifications provide new options to help both taxpayers...more
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In this episode I being a two part series on how to manage your third party relationships under the FPCA and UK Bribery Act. In this episode, steps 1-the Business Justification and Step 2-the Questionnaire. ...more
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ROBERT Koren is hoping Albion stay in tune for a title triumph - because 'We are the Champions' is the only English song he knows!
The on-song Slovenian midfielder is desperate for West Brom to finish in top spot so that he can lead a chorus of the Queen classic.
Koren, pictured, has become better known for belting in smashing goals than belting out smash hits with nine league strikes so far this season.
But he admits that his choice of karaoke song is quite appropriate as Tony Mowbray's men close in on the Championship silverware.
"I don't know many English songs,"said Koren. "Most of the ones I could sing would be in Slovenian! If I had to choose, I would pick 'We are the Champions' by Queen.
"I know a lot of the words to that one.
"It's a good song so hopefully I will be singing it soon. It's really popular back home and when teams are winning it's always played."
Koren was Mowbray's first signing when he joined from Norwegian club Lillestrom last January.
But he admits the biggest culture shock he received in English football was the pre-match music blaring out of the Baggies dressing room.
"It's not easy when you're coming from another country, everything's different and it's a different culture," said Koren. "For me the most strange thing is that we're listening to music before the game. I've never done that before. But it creates a really chilled out atmosphere so it's really positive."
Koren's creative qualities have helped Albion storm to the top of the Championship hit parade.
And the 27-year-old playmaker is backing the Baggies to still be at number one when the season ends a week today.
"Throughout the whole season we have proved that we play with a good style," added Koren.
"But in the end it's always about the results and you need to be focused on doing your job right and staying at the top."
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Today is most likely the last day for people to download CSS. It won't be back up on my site for a long long time. (If ever). I must thank Larissa for hosting it via the secure link as well.
alatri wrote:Or you can ask Anneke to send you a CD. Anneke -- are you going to put CSS on the CD at the Distribution Center?
-- Larissa ^..^
Users browsing this forum: Dradix78 and 3 guests


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Fox Ridge Apartments1445 4th St. Dr NW Apt 35, Hickory, NC 28601 View On Map (828) 322-6684
For rates, availability, and other information fill out the availability request form and a representative from Fox Ridge Apartments will contact you shortly
Fox Ridge Apartments is located in the Charlotte Area in the 28601 zip code. View this apartment on a map.
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Set to begin a new session Monday, lawmakers are struggling to find optimism that 2014 will mark a pivot point for an institution whose historically low approval rating has been at or below 20 percent for three years. Last year seemed to bring a rock-bottom moment — not just in the public's view but also across the Capitol, where ambition withered among lawmakers themselves.Gee, Roy. You're more frustrated than any of us ... and yet you're a Republican in Congress in Washington, D.C. and you don't think you're the problem? Must be nice to have a job where you can spend all day screwing up and then spend all night claiming nobody's angrier about it than you are.
"Legislators give up on the process, and either before or right after they've done that, the people that we work for give up on the process," said Sen. Roy Blunt (R-Mo.), a 17-year veteran of the House and the Senate. He summed up the malaise that some members of Congress feel: "Whenever anybody tells me, 'I'm frustrated with the way the Senate and the Congress are working,' I say: 'I fully understand. I'm more frustrated with this than you are.' "
Meanwhile, D.C. reporters have decided how to think about the return of Republicans on the other side of The Hill:
As House Republicans return to Washington for the new year, their leaders must decide how ambitious the party will be in the 10 months before their majority faces voters in November.And as Laura Clawson wrote this morning, we may have an answer:
Republicans expected to block unemployment aidLooks like they are choosing "ambition." Just like last year.
Email your member of Congress now to demand that they restore benefits to the Emergency Unemployment Compensation program.


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- Shopping Bag ( 0 items )
From the Publisher"A simply wonderful book from the master historian of Catholicism in America."—Jon Butler, author of Awash in a Sea of Faith: Christianizing the American People
"A tour de force of mature scholarship, careful but critical thought, and engaging prose.... A bold departure from earlier social histories of American Catholicism."—Harry S. Stout, author of The New England Soul: Preaching and Religious Culture in Colonial New England
"The capstone to Dolan's celebrated career. Put simply, he argues that America has been quite good for Catholicism and that Catholicism must continue to adapt to American culture if it is to endure, let alone flourish."—Christian Century
"This absorbing inquiry answers the often troubling question of what it means to be both a Catholic and an American."—Booklist
"Ideal as an introduction to the main issues and characters in American Catholic history." —Patrick Allit, Professor of History, Emory University, in The Journal of American History
"A brilliant study about the relationship between Catholicism and American democratic ideals, this timely book considers the historical foundations and subsequent evolutions of Catholicism's adaptation to and influence on American self-understanding. This well-documented, and lucidly written book is essential reading for all Americans interested in religion and politics. Wholeheartedly recommended."—Library Journal
"An eminent Catholic historian examines the ways American culture and Catholicism have affected one another. In his most engaging section, covering the past 40 years, he reveals his great admiration for John XXIII and his disdain for the conservative, authoritarian policies of the current pontiff. He does a good job, as well, of showing how Hispanic and black Catholics have affected the church as a whole."—Kirkus Reviews
"Can the church achieve an American version of Catholicism without getting swallowed up in the all-enveloping American culture? The answer to that question is still very much in doubt, as Dolan acknowledges, and his extended essay is a compact guide to the twisty accommodations that have evolved over the last 200 years."—Los Angeles Times
"It is ideal as an introduction to the main issues and characters in American Catholic history."—Patrick Allitt, Professor of History, Emory University, The Journal of American History


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Dental Care for Babies Center - Bullhead City, AZ
WebMD Physician Directory
Bullhead City, Arizona
Dental Care for Babies
When to Start Caring for Your Baby's Teeth
It's a good idea to get in the habit of cleaning your baby's gums even before teeth emerge.
To clean your baby's mouth:
Other Related Dental Care for Babies Articles
Emergency Contact for Bullhead City
Nearby Bullhead City Hospitals *
Western Arizona Regional Med Ct
Valley View Medical Center
Colorado River Medical Center
Kingman Regional Medical Center
*Provider Directory Terms of Use:
The WebMD 'Provider Directory' is provided by WebMD for use by the general public as a quick reference of information about Providers. The Provider Directory is not intended as a tool for verifying the credentials, qualifications, or abilities of any Provider contained therein. Inclusion in the Provider Directory does not imply recommendation or endorsement nor does omission in the Provider Directory imply WebMD disapproval.


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challenge of data assimilation, in which we wish to use new data to update model parameters without reanalyzing the entire data set. This is essential when new waves of data continue to arrive, or subsets are analyzed in isolation of one another, and one aims to improve the model and inferences in an adaptive fashion—for example, with streaming algorithms. The mathematical sciences contribute in important ways to the development of new algorithms and methods of analysis, as do other areas as well.
Simplifying the data so as to find their underlying structure is usually essential in large data sets. The general goal of dimensionality taking data with a large number of measurements and finding which combinations of the measurements are sufficient to embody the essential features of the data set—is pervasive. Various methods with their roots in linear algebra, statistics, and, increasingly, deep results from real analysis and probabilistic methods—such as random projections and diffusion geometry—are used in different circumstances, and improvements are still needed. Such issues are central to NSF's Core Techniques and Technologies for Advancing Big Data Science and Engineering program and to data as diverse as those from climate, genomics, and threat reduction. Related to search and also to dimensionality reduction is the issue of anomaly detection—detecting which changes in a large system are abnormal or dangerous, often characterized as the needle-in-a-haystack problem. The Defense Advanced Research Projects Agency (DARPA) has its Anomaly Detection at Multiple Scales program on anomaly-detection and characterization in massive data sets, with a particular focus on insider-threat detection, in which anomalous actions by an individual are detected against a background of routine network activity. A wide range of statistical and machine learning techniques can be brought to bear on this, some growing out of statistical techniques originally used for quality control, others pioneered by mathematicians in detecting credit card fraud.
Two types of data that are extraordinarily important yet exceptionally subtle to analyze are words and images. The fields of text mining and natural language processing deal with finding and extracting information and knowledge from a variety of textual sources, and creating probabilistic models of how language and grammatical structures are generated. Image processing, machine vision, and image analysis attempt to restore noisy image data into a form that can be processed by the human eye, or to bypass the human eye altogether and understand and represent within a computer what is going on in an image without human intervention.
Related to image analysis is the problem of finding an appropriate language for describing shape. Multiple approaches, from level sets to "eigenshapes," come in, with differential geometry playing a central role. As part of this problem, methods are needed to describe small deformations of shapes, usually using some aspect of the geometry of the space of


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Louis Tomlinson with any girl who isn't us still breaks our hearts but the blow of seeing the One Direction hottie next to his model girlfriend Eleanor Calder was softened when we saw how happy he looked!
Louis Tomlisnon tweeted this photo of him with his girlfriend Eleanor Calder. Copyright [Twittr/Louis Tomlinso …
Before Louis returned to the studio to record One Direction's second album, he hit celebrity holiday hotspot, St Tropez — where Rihanna has recently been partying aboard a private yacht.
[Related story: Louis Tomlinson going deaf because of screaming fans]
[Related story: Louis Tomlinson treats his girlfriend to incredible birthday]
Yesterday Louis shared this cute snap of him and Eleanor sunning themselves by the pool and we literally cannot believe how perfect they look.
Not only is Louis' torso toned and gorgeous, his equally as hot gf, Eleanor has one incredible bikini body!
And how come our hair never looks that good in a messy up do? #nofair
After posting the photo Louis quickly deleted it… we're not sure why! But luckily we had time to share it with you.
Last night he fell victim to some prank calling from Tulisa who took part in a Twitter chat with and decided to call the One Direction star.
Following the silly exchange Louis tweeted: "Very funny @officialTulisa!"
And a somewhat apologetic Tulisa replied with: "soz babe we had 2 get ya! Thanks for 4 being a laugh n entertaining us! [sic]"
It's nice to hear he's a good sport too!


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- 2-hour tour of Vancouver's most popular food trucks
- Dine on four items including a famous Japadog, smoked wild salmon sandwich, butter chicken and more!
- Sample fresh, a unique beverage and a fiery diablo cookie
- Enjoy being led by a passionate, local foodie guide
- This tour has been named a Canadian Signature Experience by the Canadian Tourism Commission
Recent Photos of This Tour
What You Can Expect
Your exciting food experiences will be the highlight of your trip to Vancouver. See how wild BC salmon is hot smoked inside a tiny, 8-by-14-foot (2-by-4-meter) food cart. Meet chefs, truck owners and food artisans. Get recipes and tips to re-create your favorite street eats in your own kitchen. And wrap up your lunchtime adventure with a spicy diablo cookie that will set you on fire!
Please note: If you require vegetarian or pescetarian tastings, please advise in the Special Requirements box at check-out. Due to the mobile nature of food trucks, tastings and food trucks visited during the tour are subject to change without prior notice.
This tour is part of the Canadian Signature Experiences collection, a group of tourism businesses designated by the Canadian Tourism Commission as tours and activities that provide an authentic and distinctive Canadian travel experience.
Sample Tasting Menu (subject to change without prior notice)
1. Kurobuta Terimayo Japadog
2. Butter chicken naan kebab
3. Hot smoked wild salmon sandwich
4. Japanese chicken Karaage
7. Diablo cookie
Customer Reviews
October 2014
This was a great experience at excellent value. Excellent hosts from Vancouver Foodie Tours. Good fun, wonderful food and bonus info on the city. Would even do it again on my next trip! Hope they keep growing and offering new tours. Well done.
September 2014
Such a great tour! Our guide, Lisa was lovely and very knowledgable about food and Vancouver in general. We were a group of 10 and visited 5 trucks all within a short distance of each other. our tastings included hoisin chicken wrap, grilled cheese sandwich, pulled pork poutine, cod and salmon salad and fish tacos (my fave). We had the most amazing weather which was a bonus! So glad we did this tour, highly recommend!