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Press release from Marketwire
Richmont Mines Reports Strong Results in the First Quarter of 2011
Thursday, May 12, 2011
Richmont Mines Reports Strong Results in the First Quarter of 201116:28 EDT Thursday, May 12, 2011MONTREAL, QUEBEC, CANADA--(Marketwire - May 12, 2011) - Richmont Mines Inc. (TSX:RIC)(NYSE Amex:RIC), ("Richmont" or the "Company") is pleased to announce financial and operational results for its first quarter ended March 31, 2011. Financial results are based on International Financial Reporting Standards ("IFRS") and dollars are reported in Canadian currency, unless otherwise noted.Highlights:Q1 2011 net earnings of $8.7 million, or $0.28 per share, versus Q1 2010 net earnings of $1.8 million, or $0.07 per share; Gold sales of 19,234 ounces at an average selling price of US$1,389 (CAN$1,369) in Q1 2011, versus gold sales of 15,841 ounces at an average selling price of US$1,116 (CAN$1,149) in the prior year; Significant increase in resource base at Wasamac; 35,000 metre drill program on Wasamac in 2011 continues to yield positive results; Strong initial drill result on Monique property; exploration program extended to 8,170 metres from 5,500 metres; Sale of Valentine Lake property completed for proceeds of CAN$3.0 million; Strong financial position: $47.0 million in cash and cash equivalents and no long-term debt at March 31, 2011. Commenting on the first quarter, Mr. Martin Rivard, President and CEO of Richmont Mines noted: "We are very pleased with our first quarter results. Recovered grades were notably higher at both of our operating mines year-over-year, with grades up 22% at the Island Gold Mine and up 37% at our Beaufor Mine. Island Gold Mine had a particularly strong first quarter, with tonnage levels and gold recovery rates also improving by a respective 7% and 2% year-over-year. Combined, these factors translated into a first quarter cost per tonne at Island Gold of $128, a notable 13% decrease from the 2010 annual rate of $147 per tonne for this mine. Recovered grades improved significantly at Beaufor, 18,826 tonnes of ore were processed this quarter and the remaining stockpile of 7,932 tonnes available at the end of Q1 was processed in Q2. This, in conjunction with the fact that more development is necessary to access ore zones at this mine, resulted in higher cash costs. As we have stated in the past, extensive development will be needed to access mining zones at Beaufor on a go-forward basis and, as a result, cash costs will remain at current levels. However, we continue to assess our mining plans in order to reach mineable reserves more efficiently, and are also actively evaluating the potential of promising near-surface zones on the property."Commenting on the Company's exploration efforts, Mr. Rivard added: "On the exploration front, we had a very active quarter. We completed 9,900 out of our planned 35,000 metre exploration program on Wasamac in 2011, and approximately 8,000 metres of exploration drilling on our Monique property. To date, preliminary drill results at both of these projects have been very favourable, and we look forward to further evaluating their potential long-term benefit for the Company as 2011 progresses."Revenue for the first quarter of 2011 was $26.4 million up 32% from revenues of $20.0 million in the first quarter of 2010. A total of 19,234 ounces of gold were sold at an average price of US$1,389 (CAN$1,369) per ounce in the current quarter, versus gold sales of 15,841 ounces and an average realized sales price of US$1,116 (CAN$1,149) per ounce in the same period last year. Total precious metals revenue increased notably to $26.3 million from $18.2 million in the first quarter of 2010, a reflection of the 21% increase in the number of ounces sold, and the 19% increase in the average selling price per ounce in Canadian dollars.Cost of sales, which includes operating costs, royalties, custom milling expenses and some related amortization expense, totalled $16.5 million in the first quarter of 2011, up slightly from $16.1 million in the comparable period last year. The increase reflected higher costs per tonne at the Beaufor Mine, increased milling costs and higher amortization expense related to increased sales and a higher depreciation rate. These were partially mitigated by lower custom milling expenses reflecting the fact that no custom milling was performed during the current quarter. The average cash cost per ounce of gold sold declined 12% in US dollar terms and 15% in Canadian dollar terms, to US$743 (CAN$732) in the first quarter, from US$841 (CAN$866) in the first quarter of 2010. This substantial decline was mostly driven by higher recovered grades at both operating mines and higher tonnage at the Island Gold Mine.Exploration and project evaluation costs totalled $0.9 million in the first quarter of 2011, versus $0.8 million spent in the same period last year. However, when excluding exploration tax credits of $1.6 million during the current quarter and $0.4 million in the comparable period of 2010, exploration and project evaluation costs were $2.5 million and $1.2 million respectively. The year-over-year increase was driven by a significant expansion in exploration drilling, most notably on the Wasamac and Monique properties. On a segmented basis, exploration costs before tax credits were approximately $0.2 million at the Beaufor Mine, $0.4 million at the Island Gold Mine, $0.7 million on Wasamac, and $0.9 million on Monique, while exploration and project evaluations costs at other properties amounted to $0.3 million during the current quarter.Net earnings for the first quarter of 2011, which include proceeds from the sale of Valentine Lake, increased significantly to $8.7 million, or $0.28 per share, compared with net earnings of $1.8 million, or $0.07 per share, in the first quarter of 2010.First Quarter NewsWasamac Exploration PropertyRichmont announced a significant increase in the estimated resource base for the Wasamac property during the first quarter of 2011. Specifically, Measured and Indicated Resources for the property as of December 31, 2010, were estimated at 5,093,180 tonnes grading 2.51 g/t Au for 411,073 ounces of gold, and Inferred Resources were estimated at 11,515,020 tonnes grading 2.72 g/t Au for 1,007,875 ounces of gold, a notable increase from 285,200 ounces of Inferred Resources at December 31, 2009. An R 43-101 technical report was filed on April 1, 2011. Please see the February 17, 2011 press release entitled "Richmont Mines announces Resources of over 1 million ounces of gold at its Wasamac property" for additional details.The Company also announced that it would complete an additional 35,000 m of drilling on Wasamac in 2011, with the main objective of expanding overall resources and setting the parameters for completing a scoping study by the end of 2011. Drilling is focused along a horizontal strike length of 2 km, and is targeting a maximum vertical depth of approximately -800 metres. Preliminary results from the first 9,900 metres completed on this campaign in 2011 have been favourable. Specifically, new results include 3.45 g/t Au over 46.60 metres, 2.66 g/t Au over 68.42 metres, 2.16 g/t Au over 65.66 metres, and 3.38 g/t Au over 13.68 metres. These results further reaffirm the Company's view that the property has the potential for an underground bulk mining operation.Option Agreement Signed with GlobexIn May 2011, the Company announced that it had entered into an option agreement with Globex Mining Enterprises Inc. to acquire a 100% interest in 5 claims adjacent to Richmont's Wasamac property. The Company plans to begin exploration work on the land package this summer, with the objective of verifying the potential presence of mineralized trends similar to those observed on the Wasamac property at deeper elevations. The 5 claims cover a total area of 2.07 km2 (207 hectares), are less than 15 km west of Rouyn-Noranda, Quebec, and are approximately 10 km east of the Company's Francoeur Mine. Please see the May 9, 2011 press release entitled "Richmont mines signs option agreement with Globex; Expands Wasamac exploration package" for details.Monique Exploration PropertyFollowing very favourable initial results from the drill program on the Monique property, Richmont announced that the 2011 program was extended from 5,500 to 8,170 metres and that results obtained to date reaffirmed the Company's commitment to the project. Specifically, preliminary results obtained from the G Zone included 6.76 g/t Au over 12.9 metres, 8.07 g/t Au over 10.0 metres, 4.25 g/t Au over 17.1 metres, and 6.20 g/t Au over 11.1 metres (all true widths). The Company similarly noted that geotechnical work and condemnation drilling on the property were progressing well, and that results from the drilling program will be used to complete an R 43-101 compliant technical report during the fourth quarter of 2011. Richmont also announced that it had met all of the requirements of the option agreement with SOQUEM and that, consequently, SOQUEM'S 19% ownership transfer was underway. Please see the April 11, 2011 press release entitled "Monique work commitment completed; Initial drill results confirm strong near surface gold mineralization" for additional details. Francoeur MineA total of $3.8 million has been invested at the Francoeur Mine in the first three months of the year, as development efforts are progressing with 2,331 metres of underground development and 5,792 metres of definition drilling completed as of March 31, 2011. Drift excavation is focused on levels 15, 16 and 17. While access to the mineralized zone was achieved on level 15, development to reach the West Zone on levels 16 and 17 is expected to be completed in the third quarter of 2011. Definition drilling in the area above level 15 has not confirmed a sufficient number of mining areas to support an acceptable production rate. To achieve this, additional development as well as stope preparation work is required on levels 16 and 17. The Company anticipates that milling of development ore will begin in the third quarter of 2011. However, commercial production levels will not be reached in mid-2011 as previously planned, but should be achieved in the first quarter of 2012. Despite challenging conditions to recruit specialized workers, the Company is pleased to report that the Francoeur Mine work force at the end of the quarter totalled 90 employees. The mine has an annual estimated production rate of 35,000 ounces of gold for an initial mine life of four years. Sale of Valentine Lake Property CompletedIn January 2011, the Company announced that it had received the $3.0 million payment from Mountain Lake Resources Inc. ("Mountain Lake") that was required to fulfill the final condition set out in the February 2009 option agreement, giving Mountain Lake the option to acquire Richmont's 70% interest in the Valentine Lake property, located in Newfoundland. In accordance with the terms set out in the agreement, Mountain Lake paid Richmont an option fee of 2,500,000 of its common shares in April 2009, incurred $1.0 million of exploration and development expenditures on the property, and paid Richmont a sum of $3.0 million in cash on January 24, 2011. With all conditions met, Richmont proceeded with the transfer of its 70% interest in the Valentine Lake property to Mountain Lake. Strong Cash Position and Solid Capital StructureCash and cash equivalents totalled $47.0 million at March 31, 2011, up 18% or $7.0 million from the December 31, 2010 year-end level of $40.0 million. While this includes $3.0 million obtained from the sale of the Valentine Lake property, this was achieved despite the Company's $8.6 million of capital expenditures, and exploration and project evaluation investments made during the quarter. The cash equivalents included $10.6 million of term deposits with high level credit ratings and $36.4 million in cash deposited in Canadian chartered banks.As of March 31, 2011, Richmont Mines had 431 employees, working capital of $50.0 million, 31.4 million shares outstanding and continued to have no long-term debt obligations and no hedging contracts.Island Gold MineThree months endedMarch 31,March 31,20112010Tonnes72,38067,735Head grade (g/t)6.395.37Gold recovery (%)95.7393.49Recovered grade (g/t)6.125.02Ounces sold14,23310,938Cash cost per ounce (US$)661845During the first quarter of 2011, the Island Gold Mine processed 72,380 tonnes of ore, a 7% increase over the 67,735 tonnes of ore processed in the first quarter of 2010. The improvement reflects heightened productivity levels at the mine and at the mill, which attained an average daily output of 736 tonnes per day in the current quarter that was driven by the mill expansion completed at the end of the third quarter of 2010. The cash cost per ounce sold improved notably to US$661 (CAN$651) in the current quarter, from US$845 (CAN$870) last year, primarily due to a higher average recovered grade of 6.12 g/t in the quarter, versus 5.02 g/t in the prior year and a lower year-over-year cost per tonne. Similarly, an improved recovery rate of 95.73% versus 93.49% last year, driven by the expanded mill capacity that permitted a finer grinding of the ore, also favourably impacted cash cost per ounce during the quarter. The Island Gold Mine sold a total of 14,233 ounces of gold at an average price of US$1,384 (CAN$1,364) in the first quarter of 2011, versus gold sales of 10,938 ounces at an average price of US$1,120 (CAN$1,154) per ounce in the comparable period last year.Beaufor MineThree months endedMarch 31,March 31,20112010Tonnes18,82625,262Head grade (g/t)8.386.15Gold recovery (%)98.5898.16Recovered grade (g/t)8.266.04Ounces sold5,0014,903Cash cost per ounce (US$)975832A total of 18,826 tonnes were processed from the Beaufor Mine in the first quarter of 2011, below the 25,262 tonnes processed in the comparable period of 2010. The mine output was on budget for the quarter, however a 7,932 tonne stockpile was not processed before the end of the first quarter. These tonnes have since been processed at the Camflo Mill, and will be recorded in the second quarter. While tonnage was down year-over-year, recovered grade improved significantly to 8.26 g/t in the current quarter from 6.04 g/t in the prior year, as higher grade development ore and stopes were accessed, primarily below the 20th level of the mine. Total cash cost per ounce produced rose to US$975 (CAN$961) in the current quarter, from US$832 (CAN$856) in the prior year, a reflection of lower tonnage, higher mining costs associated with increased development needed to access the mining areas, and higher milling costs due to the limited quantity of ore processed during the quarter. While the Company continues to anticipate that extensive development will be needed to access mining zones at Beaufor on a go-forward basis, recovered grades are expected to remain favourable as better grade mining areas continue to be accessed during the remainder of the year. A total of 5,001 ounces of gold were sold in the first quarter of 2011 at an average price of US$1,404 (CAN$1,384), compared to 4,903 ounces of gold sold at an average price of US$1,107 (CAN$1,140) in the comparable period of 2010.OutlookMr. Martin Rivard, President and CEO of Richmont Mines commented: "In addition to continuing to focus on optimizing production efficiencies at both our operating mines, one of our primary objectives for the remainder of 2011 is to significantly advance our exploration programs on our Wasamac and Monique properties. Furthermore, we are intently focused on bringing the Francoeur Mine into commercial production, and while this is taking more time than originally planned, we are reaffirming our production guidance of 80,000 – 85,000 ounces of gold for 2011. Last but certainly not least, we are also continuing to evaluate potential acquisition and partnership opportunities that will enable us to grow our reserve base and increase our production profile for the future."Annual and Special General MeetingThe Company will hold its Annual Meeting on Friday, May 13, 2011 in the Elisabeth conference room at the Mount Stephen Club at 9:00 am EST. The club is located at 1440 Drummond, in Montreal, Quebec. The annual meeting presentation will be available on the Company's website shortly thereafter.Martin RivardPresident and Chief Executive OfficerAbout Richmont Mines Inc.Richmont Mines has produced over 1,200,000 ounces of gold from its operations in Quebec, Ontario and Newfoundland since beginning production in 1991. The Company currently produces gold from its Island Gold and Beaufor mines, and is currently advancing the Francoeur Mine to commercial production, which will increase Richmont's production to 100,000 ounces of gold on an annual basis. With extensive experience in gold exploration, development and mining, the Company is well positioned to cost-effectively build its North American reserve base through a combination of organic growth, strategic acquisitions and partnerships. Richmont routinely posts news and other important information on its website (www.richmont-mines.com).Forward-Looking StatementsThis news release contains forward-looking statements that include risks and uncertainties. When used in this news release, the words "estimate", "project", "anticipate", "expect", "intend", "believe", "hope", "may" and similar expressions, as well as "will", "shall" and other indications of future tense, are intended to identify forward-looking statements. The forward-looking statements are based on current expectations and apply only as of the date on which they were made.The factors that could cause actual results to differ materially from those indicated in such forward-looking statements include changes in the prevailing price of gold, the Canadian-United States exchange rate, grade of ore mined and unforeseen difficulties in mining operations that could affect revenue and production costs. Other factors such as uncertainties regarding government regulations could also affect the results. Other risks may be set out in Richmont Mines' Annual Information Form, Annual Reports and periodic reports.Regulation 43-101 ("R 43-101")The geological data in this news releas has been reviewed by Mr. Daniel Adam, Geo., Ph.D, Exploration Manager, an employee of Richmont Mines Inc., and a qualified person as defined by R 43-101. Cautionary Note to U.S. Investors Concerning Resource EstimatesInformation in this press release is intended to comply with the requirements of the Toronto Stock Exchange and applicable Canadian securities legislation, which differ in certain respects with the rules and regulations promulgated under the United States Securities Exchange Act of 1934, as amended ("Exchange Act"), as promulgated by the SEC. The reserve and resource estimates in this press release were prepared in accordance with R 43-101 adopted by the Canadian Securities Administrators. The requirements of R 43-101 differ significantly from the requirements of the United States Securities and Exchange Commission (the "SEC"). U.S. Investors are urged to consider the disclosure in our annual report on Form 20-F, File No. 001-14598, as filed with the SEC under the Exchange Act, which may be obtained from us (without cost) or from the SEC's web site: http://sec.gov/edgar.shtml.EXPLORATION AND PROJECT EVALUATIONThree months endedMarch 31,March 31,20112010$$Exploration costs – MinesBeaufor231296Island Gold436484Francoeur3835705815Exploration costs – Other propertiesWasamac74035Monique9161Other32213Project evaluation971161,785365Exploration and project evaluation before depreciation and exploration tax credits2,4901,180Depreciation3634Exploration tax credits(1,632)(404)894810FINANCIAL DATAThree-month periodended March 31,CAN$20112010Results (in thousands of $)Revenue26,42919,964Net earnings8,7121,842Cash flow from operating activities9,6105,208Results per share ($)Net earnings basic0.280.07Net earnings diluted0.270.07Cash flow from operating activities0.310.20Basic weighted average number of common shares outstanding (thousands)31,27126,111Diluted weighted average number of common shares outstanding (thousands)31,76326,315Average selling price of gold per ounce1,3691,149Average selling price of gold per ounce (US$)1,3891,116March 31,December 31,20112010Financial position (in thousands of $)Total assets128,516115,305Working capital50,04543,880Long-term debt--SALES AND PRODUCTION DATAThree-month period ended March 31,Ounces of goldCash cost(per ounce sold)YearSalesProductionUS$CAN$Island Gold Mine201114,23314,430661651201010,9389,529845870Beaufor Mine20115,0014,46797596120104,9035,635832856Total201119,23418,897743732201015,84115,164841866Average exchange rate used for 2010: US$1 = CAN$1.0299 2011 estimated exchange rate: US$1 = CAN$0.9855 CONSOLIDATED INCOME STATEMENT(in thousands of Canadian dollars)(Unaudited)Three months endedMarch 31,March 31,20112010$$REVENUEPrecious metals26,33818,207Other income911,75726,42919,964EXPENSESCost of sales16,45516,062Exploration and project evaluation894810Administration1,3011,105Gain on disposal of long term assets(3,000)(489)15,65017,488OPERATING EARNINGS10,7792,476Accretion expense – asset retirement obligations3229Financial revenue(51)(30)EARNINGS BEFORE MINING AND INCOME TAXES10,7982,477MINING AND INCOME TAXES2,086612NET EARNINGS FOR THE PERIOD8,7121,865NET EARNINGS ATTRIBUTABLE TO NON-CONTROLLING INTERESTS-23NET EARNINGS ATTRIBUABLE TORICHMONT MINES SHAREHOLDERS8,7121,842EARNINGS PER SHAREbasic0.280.07diluted0.270.07WEIGHTED AVERAGE NUMBER OFCOMMON SHARES OUTSTANDING (thousands)31,27126,111DILUTED WEIGHTED AVERAGE NUMBER OFCOMMON SHARES OUTSTANDING (thousands)31,76326,315See accompanying notes to consolidated financial statements available on SEDAR (www.sedar.com).CONSOLIDATED STATEMENT OF FINANCIAL POSITION(in thousands of Canadian dollars)(Unaudited)March 31,December 31,20112010$$ASSETSCURRENT ASSETSCash and cash equivalents47,04840,030Shares of publicly-traded companies1,0261,311Receivables1,7141,892Income and mining tax assets1,6381,745Exploration tax credits receivable4,4603,474Inventories9,2317,36465,11755,816RESTRICTED DEPOSITS290290PROPERTY, PLANT AND EQUIPMENT63,10959,199TOTAL ASSETS128,516115,305LIABILITIESCURRENT LIABILITIESPayables, accruals and provisions11,1939,262Income and mining taxes payable3,8792,67415,07211,936ASSET RETIREMENT OBLIGATIONS6,3756,343DEFERRED MINING TAXES3,1172,235TOTAL LIABILITIES24,56420,514EQUITYShare capital89,41788,743Contributed surplus6,7436,709Retained earnings7,234(1,478)Accumulated other comprehensive income558817TOTAL EQUITY ATTRIBUTABLE TORICHMONT MINES SHAREHOLDERS103,95294,791TOTAL EQUITY AND LIABILITIES128,516115,305See accompanying notes to consolidated financial statements available on SEDAR (www.sedar.com).CONSOLIDATED STATEMENT OF CASH FLOW(in thousands of Canadian dollars)(Unaudited)Three months endedMarch 31,March 31,20112010$$OPERATING ACTIVITIESNet earnings before mining and income taxes for the period10,7982,477Taxes received108305Adjustments for:Depreciation and depletion2,4401,458Stock-based compensation216276Accretion expense – asset retirement obligations3229Gain on disposal of long-term assets(3,000)(489)Gain on disposal of shares of publicly-traded companies(43)-10,5514,056Net change in non-cash working capital items(941)1,152Cash flow from operating activities9,6105,208INVESTING ACTIVITIESDisposition of shares of publicly-traded companies69-Property, plant and equipment – Francoeur Mine(3,819)(1,300)Property, plant and equipment – Island Gold Mine(1,334)(1,485)Property, plant and equipment – Beaufor Mine(907)(698)Property, plant and equipment – Other(93)(92)Disposition of long-term assets3,000533Cash used in investing activities(3,084)(3,042)FINANCING ACTIVITIESIssue of common shares49234Cash flow from financing activities49234Net change in cash and cash equivalents7,0182,200Cash and cash equivalents, beginning of period40,03021,139Cash and cash equivalents, end of period47,04823,339See accompanying notes to consolidated financial statements available on SEDAR (www.sedar.com).FOR FURTHER INFORMATION PLEASE CONTACT: Jennifer AitkenInvestor Relations:RICHMONT MINES INC.514 email@example.com BolducMedia Contact:EDELMAN Public Relations514 844-6665 ext. firstname.lastname@example.com


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There's no doubt the Apple 1 is an iconic computer. We decided to re-create this classic machine with the help of an unassembled kit. Find out how we got on.
Early computers were designed for functionality, not aesthetics. The Apple 1 did not come with a case; hobbyists instead designed their own, including carving wooden cases or retrofitting briefcases.
The Replica 1 is similarly utilitarian, so there's a power LED right on the board to indicate the on/off state. Here I'm holding the LED, which has two leads that slide into the appropriate holes, in my left hand; the longer lead is the positive end and is inserted where the + symbol indicates.
Top photo
Here, some of the interface components are being inserted and soldered.
Bottom photo
From left to right are a composite video output, a serial port, a DC power input, and the on/off switch. Not all of these parts were included in the original Apple 1; the RS232 serial port, for example, allows the Replica 1 to interface with and download data from modern computers.
See all laptop reviews
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Bordeaux Cathedral
Bordeaux Cathedral (Cathédrale Saint-André de Bordeaux) is a Roman Catholic cathedral, seat of the Archbishop of Bordeaux-Bazas, located in Bordeaux.
The cathedral was consecrated by Pope Urban II in 1096. Of the original Romanesque edifice, only a wall in the nave remains. The Royal Gate is from the early 13th century, while the rest of the construction is mostly from the 14th-15th centuries. The building is a national monument of France.
In this church in 1137 the 13-year-old Eleanor of Aquitaine married the future Louis VII, a few months before she became Queen.
A separate bell tower, the Tour Pey-Berland, is next to the cathedral.
The site is served by line A and line B of the tramway de Bordeaux at Station Hôtel de Ville.
Marcadé collection[edit]
The Cathedral is home to the Marcadé collection, which consists of a group of forty-two illuminations, among other objects (paintings, sculptures, liturgical vestments and silver objects). It was given to the Cathedral of Bordeaux by canon Marcadé in 1947. Of note, these illuminations, little studied so far, will be exhibited starting in 2015 in the cathedral, in a room specially designed for this collection. [1]
See also[edit]
Article incorporates text licensed under the CC-by license from Heritage Science as cited
- ^ Mounier, Aurélie et al. (October 24, 2014). "Hyperspectral imaging, spectrofluorimetry, FORS and XRF for the non-invasive study of medieval miniatures materials". Heritage Science (Springer) 2 (24). doi:10.1186/s40494-014-0024-z. Retrieved 1 March 2015.
External links[edit]
|Wikimedia Commons has media related to Bordeaux Cathedral.
Coordinates: 44°50′16″N 0°34′39″W / 44.83778°N 0.57750°W
|This article on a Roman Catholic cathedral in France is a stub. You can help Wikipedia by expanding it.


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Surgeries and other procedures can influence the risk of death in hospital. All published scales that predict post-operative death risk require clinical data and cannot be measured using administrative data alone. This study derived and internally validated an index that can be calculated using administrative data to quantify the independent risk of hospital death after a procedure.
For all patients admitted to a single academic centre between 2004 and 2009, we estimated the risk of all-cause death using the Kaiser Permanente Inpatient Risk Adjustment Methodology (KP-IRAM). We determined whether each patient underwent one of 503 commonly performed therapeutic procedures using Canadian Classification of Interventions codes and whether each procedure was emergent or elective. Multivariate logistic regression modeling was used to measure the association of each procedure-urgency combination with death in hospital independent of the KP-IRAM risk of death. The final model was modified into a scoring system to quantify the independent influence each procedure had on the risk of death in hospital.
275 460 hospitalizations were included (137,730 derivation, 137,730 validation). In the derivation group, the median expected risk of death was 0.1% (IQR 0.01%-1.4%) with 4013 (2.9%) dying during the hospitalization. 56 distinct procedure-urgency combinations entered our final model resulting in a Procedural Index for Mortality Rating (PIMR) score values ranging from -7 to +11. In the validation group, the PIMR score significantly predicted the risk of death by itself (c-statistic 67.3%, 95% CI 66.6-68.0%) and when added to the KP-IRAM model (c-index improved significantly from 0.929 to 0.938).
We derived and internally validated an index that uses administrative data to quantify the independent association of a broad range of therapeutic procedures with risk of death in hospital. This scale will improve risk adjustment when administrative data are used for analyses.
Surgeries and procedures are major functions of hospitals that importantly influence patient outcomes and hospital performance. Procedural outcomes are often used to compare surgeons, clinical divisions, hospitals, and health jurisdictions. Many different types of surgeries and procedures exist in different specialties, involving very different patient populations. As a result, the influence of different types of procedures on hospital outcomes can vary greatly.
Quantifying the independent influence of a broad range of different types of procedures on outcomes would allow analysts, administrators, and researchers to measure, compare, and adjust for the importance of each procedure. Six indexes have been developed to quantify the risk of post-operative death after a range of surgeries (Table 1) [1-6]. Each of these indexes, however, requires clinical information that is usually unavailable in routinely collected administrative data.
Table 1. Summary of previous indexes predicting risk of death following surgery
In this study, we derived and internally validated an index to measure the influence of a broad range of surgeries on in-hospital mortality. Our goal was to quantify the independent association of all procedures with the risk of death in hospital. To do this, we first grouped procedures based on administrative codes and the procedure's urgency status and then determined which of these procedure-urgency groups were associated with risk of death in hospital after adjusting for factors that are highly predictive of this outcome. We then created a scoring system to quantify the independent association of significant procedures with risk of death in hospital. This index can be calculated using administrative data and estimates the risk of death in hospital from these procedures that is independent of other factors associated with this outcome. It can be used to help risk-adjust analyses using administrative data that have death in hospital as an outcome. Such analyses could be done to identify factors independently associated with death in hospital and, in some situations, compare quality of care between institutions.
Study Setting
This study took place at The Ottawa Hospital (TOH), a tertiary-care teaching facility with three sites that averaged 20 000 admissions annually during the study period. TOH functions within a publicly funded health care system. TOH is the sole regional provider of trauma care, thoracic surgery, and neurosurgical interventions, and provides most of the region's oncological care.
We included all admissions to the hospital (including same-day surgeries) between 1 April 2004 and 1 April 2009. "Same-day surgeries" included patients who had their surgery on the same day on which they were admitted to hospital. These patients were typically discharged home the same day but may have been kept in hospital if complications occurred or if additional monitoring was required. We started patient recruitment in April 2004 to ensure that our hospital had at least two years of experience coding procedures with the Canadian Classification of Interventions (CCI) coding system (which was introduced in April 2002). Patient recruitment ended in April 2009 (the last complete year of data available when the analyses were conducted). To apply the Kaiser Permanente In-patient Risk Adjustment Model (KP-IRAM) [7] - the method used to adjust for other risk factors associated with death in hospital - we excluded all patients with age ≤ 15 years at admission, all delivery-related obstetrical admissions, and those who were transferred to or from TOH. Throughout this study, the unit of analysis was the hospitalization.
Candidate Procedures
We used multiple binomial logistic regression to derive our index. We chose death in hospital as the model outcome because it is accurately recorded and is important to all potential users of the index. There were a total of 4013 hospital deaths (2.9% of all admissions) in the derivation cohort. Our logistic model could therefore test a maximum of 400 procedures or surgeries (i.e. 10 deaths per exposure) to safely avoid problems with over-fitting and model instability [8].
We identified candidate procedures using their Canadian Classification of Interventions (CCI) code. The CCI system contains more than 18,000 unique codes. We therefore grouped procedures using the first five alpha-numerics of each code (which identifies the anatomical area and the intervention type) and limited our study to therapeutic procedures (i.e. CCI section 1). We used the admission status of the hospitalization (i.e. elective vs. non-elective admission) to classify the procedure urgency since urgency is an important and independent predictor of post-procedural outcomes [9-14]. Procedures that could not be performed electively (such as cardiac resuscitation, implantation of an internal device in the thoracic descending aorta, and control of bleeding in the thoracic cavity) were classified as "non-elective" regardless of the admission status of the hospitalization.
There were 3984 unique procedure-urgency combinations during the study period. Since this exceeded the maximum number of variables allowed in our model without overfitting (n = 400), we used three filters to exclude procedures. First, we only included procedures that were conducted on the day of the principal procedure (defined as the procedure considered by the health records analyst to be most significant during the patient's hospital stay). In 5% of hospitalizations, coded procedures occurred on more than one day. In such cases, only procedures that occurred on the day of the principal procedure were considered. Second, procedures had to be conducted at least once per month at our hospital during the study period (independent of its urgency status). Finally, the p-value for the association of the procedure with death in hospital (after adjusting for risk of death in-hospital measured with KP-IRAM) had to be less than 0.5.
Adjusting for Risk of Death in Hospital
To adjust for risk of death in hospital due to patient and hospitalization factors, we used the Kaiser Permanente In-patient Risk Adjustment Model (KP-IRAM) [7]. This model was derived and internally validated on almost 260,000 hospitalizations at 17 hospitals belonging to the Kaiser Permanente Health Plan and was subsequently validated at our hospital [15]. The KP-IRAM includes six covariates including: patient age; patient sex; admission urgency (i.e. elective or emergent) and service (i.e. medical or surgical); admission diagnosis; severity of acute illness as measured by the Laboratory-based Acute Physiology Score (LAPS); and chronic comorbidities measured by the Comorbidity Point Score (COPS). Using the admission diagnosis, hospitalizations were grouped into "Primary Conditions," and a separate logistic regression model was created for each group. Interaction terms between age, LAPS, and comorbidity score were included. The model had excellent discrimination (c-statistic = 0.88) and calibration (p-value of Hosmer Lemeshow statistic for the entire cohort was 0.66) for all-cause death in hospital.
We made three minor modifications to the KP-IRAM for this study. First, Canada switched from the International Classification of Diseases (ICD) 9-CM system (used in the KP-IRAM) to the ICD-10-CA system in 2002. We therefore used tables (provided by Canadian Institute for Health Information) to translate ICD-9-CM admission diagnoses to ICD-10-CA codes. Second, we measured chronic comorbidities using the Elixhauser Index [16] instead of the COPS because the KP-IRAM performed equally well using either comorbidity index [15]. Finally, the KP-IRAM was calculated on the day of the procedure (rather than at admission) for people who had one of the procedures included in the model. This model was used to estimate each patient's risk of death in hospital at the time of the procedure (expressed as a number that ranged between 0 and 1).
Creation of the Procedural Index for Mortality Risk (PIMR) Score
We randomly separated patients into equally sized derivation and validation groups. Using the derivation group, we ran a binary logistic regression model with death in hospital as the outcome and the KP-IRAM estimated risk as the adjusting covariate. The index day for patients undergoing one of the procedures considered for the model was the day of the procedure. For all other patients, the index day was the day of admission. Values of all covariates for the KP-IRAM model were those on the index day. We used stepwise variable selection to identify which candidate procedure-urgency combinations were independently associated with death in hospital. Surgeries with a 2-sided p-value less than 0.05 were retained in the model.
We then used the methods described by Sullivan et. al. [17] to modify the parameter estimates of this regression model into an index. The number of points assigned to each procedure equaled its regression coefficient divided by the coefficient in the model with the smallest absolute value. We rounded this quotient to the nearest whole number. This number translated the parameter estimates into units relative to the procedure with the smallest, independently significant association with death in hospital. Therefore, the association of a procedure assigned two points was twice as important for predicting risk of death in hospital as a procedure with one point. Each person's total Procedural Independent Mortality Risk (PIMR) score was then calculated by summing up the points of all significant procedural groups for which they had been coded.
When calculating the PIMR score, we tallied up only those procedures that were performed on the index day (i.e. the day on which the principal procedure was conducted). Procedures done on other days did not influence the PIMR score. The PIMR score also did not capture whether or not the procedure was the first procedure conducted during the hospitalization.
Assessment of the PIMR score
In the validation group, we described the distribution of the PIMR score and used logistic regression to measure the association of the PIMR score alone with risk of death in hospital.
We then measured the influence of the PIMR score on risk of death in hospital independent of other factors associated with this outcome. "Discrimination" measures a model's ability to distinguish between patients who did and did not die in hospital and was measured using the c-statistic [18]. "Calibration" measures the accuracy of a model's predicted risk of death and was measured by dividing the study cohort into deciles and strata based on the estimated risk of death. Within each decile and stratum, observed and expected death rates were deemed similar if the 95% confidence interval around the former (calculated using exact methods [19]) included the latter. Overall calibration was summarized using the Hosmer Lemeshow statistic [20]. Table cells containing less than five observations were censored to maintain patient confidentiality.
In the validation group, we then compared the predictive performance of models containing the KP-IRAM with and without the PIMR score. To do this, we used two statistical measures: the Integrated Discrimination Improvement (IDI) [21] and the Net Reclassification Improvement (NRI) [22]. The IDI is the discrimination slope (the mean predicted risk in patients with the event minus that of patients without the event) of a model with the KP-IRAM and PIMR as independent predictors minus the discrimination slope of a model with the KP-IRAM alone as the independent predictor. An IDI above zero indicates improved discrimination (i.e. a larger separation in mean predicted risk between events and nonevents) with the addition of the PIMR. The NRI represents the net proportion of correct reclassification (with correct reclassification defined as the predicted risk moving upwards for events and downwards for non-events) among events and non-events (calculated separately and then summed) when the predicted risk from the model with KP-IRAM and PIMR is compared to that from the model with KP-IRAM alone. We also calculated the net number of correct reclassifications when the PIMR was added to the KP-IRAM.
SAS 9.2 (Cary, NC) was used for all analyses. The study was approved by The Ottawa Hospital Research Ethics Board.
There were 369 588 admissions to The Ottawa Hospital between 1 April 2004 and 1 April 2009. 93 971 of these hospitalizations were excluded from this study because patients were less than 15 years of age (n = 36 820), patients were transferred from or to another hospital (n = 12 931), or admissions were obstetrical and delivery-related (n = 44 220). We excluded another 157 admissions because they were missing a primary condition group (required to calculate the KP-IRAM). This left a total of 275 460 hospital admissions (137 730 in both the derivation and the validation group) consisting of 172 396 unique individuals. A description of patients in the derivation cohort is provided in Table 2. The validation group did not differ significantly from the derivation group (see additional file 1).
Table 2. Description of study hospitalizations in derivation cohort
Additional file 1. Comparison of study derivation and validation cohort. Additional file 1 contains descriptive statistics of the derivation and validation cohort.
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In the entire cohort, a total of 1939 therapeutic procedures were coded during the study period. 1436 procedures were excluded because less than one procedure per month was performed during the study period. The remaining 503 procedures included a total of 938 procedure-urgency combinations. After adjusting for the Kaiser Permanente In-patient Risk Adjustment Model (KP-IRAM) death risk estimate, the p-value of the association of 726 of these procedure-urgency combinations exceeded 0.5 in the derivation cohort and were therefore excluded. This left a total of 212 procedure-urgency combinations (including 168 individual surgeries) expressed as binomial (i.e. 1/0) variables that were offered to the logistic model (see additional file 2).
Additional file 2. List of the 212 unique procedure-urgency combinations offered to the multivariate logistic model. Additional file 2 contains the frequency (in the derivation set), description, and 5-digit CCI code of the 212 procedure-urgency combinations that were offered to the multivariate logistic model. The p-value for the association of each of these 212 procedure-urgency combinations with death in hospital was < 0.5 (after adjusting for the risk of death in-hospital, as measured with KP-IRAM).
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After adjusting for important patient and admission factors, 56 procedure-urgency combinations (comprising 52 individual procedures) were independently associated with death in hospital (Table 3). 37 emergent and eight elective procedures were independently associated with an increased risk of death in hospital, while four emergent and seven elective procedures were protective. In the validation set, there were 22 664 (16.4%) admissions where the patient underwent at least one PIMR procedure, with 83% of these procedures occurring within the first three days of the hospitalization. Procedures having the strongest association with death in hospital included cardiac resuscitation, ventriculectomy, pericardial drainage, and pelvic irradiation. A full description of each procedure that was independently associated with death in hospital is given in Additional File 3.
Table 3. Procedures independently associated with death in hospital
Additional file 3. Full description of all procedure-urgency combinations independently associated with in-hospital death. Additional file 3 contains the frequency and full CCI code and description of all procedure-urgency combinations independently associated with in-hospital death (i.e. included in the PIMR index), as observed in the derivation set.
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Four procedures were independently associated with risk of death in hospital regardless of whether the procedure was done emergently or electively (Table 4). In two cases, the elective version of the procedure was assigned more points (indicating a higher risk of death in hospital) than the emergent version of the procedure.
Table 4. Procedures independently associated with risk of death in-hospital regardless of procedure urgency
Parameter estimates for procedures in the final logistic model were modified into the Procedural Index for Mortality Risk (PIMR) score (Table 3). The PIMR score for individual procedures ranged from -7 to +11. Since 84% of admissions had none of the included procedures, most hospitalizations had a total PIMR score of 0 (Figure 1, left axis). The risk of death in hospital was significantly associated with the PIMR score (Figure 1, right axis). By itself, the PIMR score was moderately discriminative for death in hospital (c-statistic 67.3%, 95% CI 66.6%-68.0%).
Figure 1. Frequency distribution of the total Procedural Index for Mortality Risk (PIMR) score among validation admissions. The horizontal axis presents the total PIMR score. The bars and left vertical axis presents the percent of hospitalizations with each total PIMR score. Individual PIMR scores were grouped to contain at least 0.5% of all admissions. The line and right vertical axis presents the observed number of deaths (with 95% confidence intervals) in each PIMR score.
The total PIMR score significantly changed the expected risk of death in hospital beyond that estimated by the KP-IRAM (Figure 2). The total PIMR score also significantly improved the ability to predict risk of in-hospital death beyond that generated by the KP-IRAM. Model discrimination improved, as indicated by the c-statistic (increased from 0.929 [95% CI 0.926-0.932] to 0.938 [0.935-0.941]) and the Integrated Discrimination Improvement (IDI) (0.04327, 95% CI 0.0384-0.0482; p < .0001). Model calibration (Figure 3) did not change (Hosmer-Lemeshow fit statistic decreased from 37.56 to 36.51). The Net Reclassification Improvement (NRI) analysis showed that although the overall net proportion of correct reclassification was negative (-18.4%), the overall net number of correct reclassifications was positive (+17 923 or 13% of the entire cohort, Table 5).
Figure 2. Effect of adding the Procedural Index for Mortality Risk (PIMR) score to the Kaiser Permanente Inpatient Risk Adjustment Methodology (KP-IRAM) on predicted risk of death in hospital. This graph presents the expected probability of death in hospital (vertical axis) for varying PIMR scores (horizontal axis). Risks are presented for people whose expected risk of death in hospital (based on the KP-IRAM) was at the 25th percentile (0.01%, solid line), 50th percentile (0.11%, long-dashed line), and 75th percentile (1.35%, short-dashed line).
Figure 3. Calibration of KP-IRAM and PIMR to predict death in hospital. These figures compare observed and expected death rates when the validation group was divided into expected risk deciles (top) and strata (bottom). The decile plot presents observed mortality rates with 95% confidence intervals with those in red significantly differing from expected.
Table 5. Results of the Net Reclassification Improvement (NRI) analysis:
We derived and internally validated an index that used administrative data to quantify the relative contribution of a broad range of therapeutic procedures on the risk of death in hospital. We identified 52 procedures which (after adjusting for a robust and validated hospital mortality model) were significantly associated with the risk of death in hospital. We modified this model into an index that reflects the independent contribution of each procedure to the risk of death in hospital. By itself, and when added to an accurate model to predict hospital mortality, the total Procedural Index for Mortality Risk (PIMR) score significantly predicted risk of death in hospital.
The importance of surgical interventions on hospital outcomes is reflected by the large number of indexes that use patient and hospitalization factors to predict the risk of post-procedural death (Table 1) [1-6]. The clinical variables in these indexes, along with their simplicity, increase their face validity to practicing clinicians. However, these clinical variables prohibit calculation of these indexes using administrative data. To develop our index, we started with a validated, highly accurate model to predict hospital mortality risk in all hospital patients. We then determined the risk of death after a broad range of procedures independent of that predicted from the KP-IRAM. Both by itself and when added to the KP-IRAM model, the PIMR was significantly associated with the risk of death in hospital.
The PIMR would primarily be used in analyses involving administrative data. Expressing this risk as a simple score facilitates our understanding of the relative importance of various interventions on death in hospital. When combined with the KP-IRAM, the PIMR had excellent discrimination and calibration for predicting risk of death in hospital. It is notable that the discrimination achieved with the KP-IRAM and PIMR was similar to that achieved using clinical based models (Table 1). The PIMR will allow researchers and administrators to gauge patient and procedural complexity of individual surgeons, services, or hospitals for descriptive or comparative purposes and will also let analysts adjust for the influence of a large range of therapeutic procedures on risk of hospital mortality.
The independent association between many of the PIMR procedures and risk of hospital death may reflect unresolved confounding of patient or hospitalization factors. The significance of several procedures (e.g. cardiac resuscitation) is likely due to important clinical events (e.g. cardiac arrest) that are identified by the procedure code and are not captured by the KP-IRAM. Further work is required to determine how much mortality risk is due to the procedure and how much is due to other underlying patient factors.
The addition of the PIMR to the KP-IRAM model significantly improved the ability to predict hospital mortality. The absolute increase of the model's c-statistic was small (0.009 or 0.9%). Several studies have shown that the overall, sequential improvement of model performance decreases as more and more variables are added [23,24]. However, the c-statistic of the KP-IRAM was already very high without the PIMR score (92.9%). With the PIMR, the C-statistic increased more than 10% of the distance between the KP-IRAM and perfect discrimination. This indicates, along with the results presented in Figure 1, the strength of PIMR to predict risk of death with or without other covariates associated with death risk in hospital.
We believe that two steps could greatly improve the PIMR. The PIMR relies on procedure codes whose accuracy has not been validated. Our study's objective was to derive and validate an index that determines the independent influence of various procedures on hospital mortality. Strictly speaking, however, the PIMR measures the independent influence of codes for various procedures - rather than the procedures themselves - on hospital mortality. Without knowing the accuracy of each code for its respective procedure, we are uncertain how strong a surrogate each code is for the actual procedure. Before one uses the PIMR for individual patient risk prediction, the accuracy of the procedure codes contained in the PIMR should be validated.
The second major limitation of the PIMR is its imputation of procedural urgency using admission urgency status. For most hospitalizations, admission and procedural urgency will be identical but situations could arise in which they would differ. For example, consider a patient admitted electively for a hip replacement who has an acute myocardial infarction requiring an emergent angioplasty. In this case, the angioplasty urgency would be misclassified as an elective procedure. We believe that this bias explains why the number of points assigned to two elective procedures exceeded that for their emergent counterpart (Table 4). The PIMR could be improved by using an accurate classification of procedural urgency.
There are other limitations to the PIMR. First, the PIMR requires that surgical procedures are coded using the Canadian Classification of Interventions (CCI). Without validated translation tables to other procedural coding systems, this limits its use to Canadian institutions. Second, the PIMR was derived and validated in a single hospital. While objective and universal criteria are used to code procedures, it is possible that local coding practices could change the PIMR's validity in other patient populations. Third, most procedures are not included in the PIMR because they were not independently associated with risk of death in hospital. As a result, the PIMR should be used as an adjunct to other factors associated with risk of death in hospital - such as those in the KP-IRAM - to compare outcomes after various surgeries. Researchers should exercise some caution if this index is used when inferring institutional quality of care issues using hospital mortality. Some of the components in the PIMR (such as heart resuscitation) could result from poor quality of care, the adjustment of which could hide such problems.
Finally, our analyses did not include surgeries that were infrequently conducted at our hospital.
We have derived and internally validated an index to express the independent association of a broad range of procedures with risk of death in hospital. When this is added to a validated hospital death risk index, we can accurately predict post-procedural risk of death.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
CvW conceived of the study; directed the study design and statistical analysis; and drafted the manuscript. JW participated in the study design; performed the statistical analysis; created the tables, additional files, and figures; and edited the manuscript. CB performed the literature search and extracted the information in Table 1. AF provided the study data, participated in the study design, and reviewed the manuscript for important clinical and intellectual content. All authors have read and approved the final manuscript.
This study was supported by the Department of Medicine, University of Ottawa.
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Recently FIBA Europe TV caught up with Sean Cunningham and Toon Van Helfteren in Leiden to pick their minds on the aspirations of ZZ Leiden ahead of the up and coming EuroChallenge season.
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does everyone up here qualify for wic
We don't use WIC and I will breastfeed for as long as baby is willing and everything else we will pay for ourselves.
Because Mean Girl.
I will do the same as Pippycoke :)
We don't qualify for WIC, and I will breastfeed. I'm not sure I really understand your question, though?
Hospital birthing, vaccinating, babywearing, cloth diapering, cosleeping, breastfeeding, Disney-holic, AP SAHM of 4
Welcoming #4 4 weeks early 11-23-12
Mama to one sweet faced 2 year old boy, Jackson, and a chunky little girl brought by Santa, Julianna.
We don't qualify and I plan on breastfeeding.
A, K, and the love of our lives, J
"Am I the only one zen around here? Good Lord!"
Gold Boobies! ( o )( o )
I don't understand the question. How do you "make it yourself"? I'm planning on breastfeeding and then transitioning to formula at some point.
And I had never heard of WIC until joining this birth board but based on the the posts I've seen there's not a chance I would qualify.
We get WIC and I love getting all the milk and fruit and whatnot, it is very helpful as we barely get by on our own. I will be breastfeeding this one for at least year but probably two years so I will continue to get milk and stuff from WIC, but not formula.
I'm thinking the presupposition of the post would be that 1) many people get WIC (which is def true around where I live and with people I know) and 2) people get WIC just to pay for formula .
WIC is for very low income women and you will have monthly appointments with your caseworker, measurements of you and your baby and so on. It's not like they hand you a load of formula and send you on your merry way. My mom had it when my sister was a baby, as my parents' income was very low and they qualified.
I am committed to breastfeeding for many reasons. I nursed my DD for 37 months and my 25mo DS is "still" nursing, as nature intended. I had to pump for the first 3 months of his life due to severe birth complications we both suffered. I was hospitalized in a psych ward for PPD. If I can do it, anyone can do it.
( o ) ( o ) Diamond Milkies! DS 2yo still nursing!
( o ) ( o ) Super double platinum milkies DD 37 months!
Donated 22+ gal to MMB of Ohio


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Creamy Cheddar Cheese Popovers
8 Feb 2011
|All purpose flour
|1 Cup (16 tbs)
|Mexican seasoning/1/4 teaspoon chili powder and a dash each ground cumin, garlic powder, and oregano leaves
|1⁄2 Teaspoon
|Garlic salt
|1⁄4 Teaspoon
|Melted butter/Margarine
|1 Tablespoon
|1 Cup (16 tbs)
|Shredded sharp cheddar cheese
|4 Ounce (1 Cup)
|Ripe olives
|1⁄4 Cup (4 tbs), finely chopped
In a bowl, combine flour, Mexican seasoning, and garlic salt.
Add butter, milk, and eggs and beat, scraping bowl frequently, until very smooth (about 2 1/2 minutes at medium-high speed if using electric mixer).
Beat in cheese and olives.
Evenly distribute batter in 12 well-greased 1/2-cup-size containers (muffin tins or ovenproof glass custard cups).
Bake on center rack in the preheated 375° oven for 45 to 50 minutes or until well browned and firm to touch.
Remove from containers and serve hot.
If you like popovers to be especially dry, loosen from pan but leave sitting at an angle in cups; prick popovers' sides with a skewer and let stand in the turned-off oven with door slightly ajar for 8 to 10 minutes.
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Creamy Cheddar Cheese Popovers Recipe


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It's a BBQ lover's dream! A welcome addition to the picnic basket, this salad is full of that sweet, tangy taste usually reserved for grilled meats.
3 pounds small red potatoes, quartered
1/2 cup olive oil
1/2 cup ketchup
1/4 cup cider vinegar
1 1/2 teaspoons McCormick® Mustard, Ground
1 teaspoon McCormick® Black Pepper, Coarse Ground
1 teaspoon salt
1 1/2 cups thinly sliced celery
1 cup coarsely chopped red bell pepper
1/2 cup chopped red onion
Bring potatoes to boil in lightly salted water in large saucepot. Reduce heat and simmer 10 minutes or until fork-tender. Drain well. Cool slightly.
Mix oil, ketchup, vinegar, mustard, black pepper and salt in large bowl with wire whisk until well blended. Add potatoes, celery, bell pepper and onion; toss gently to coat.
Serve immediately or refrigerate until ready to serve.
(Amount per serving)


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Mutations in many genes affect aggressive behavior in Drosophila melanogaster
1 Department of Genetics, North Carolina State University, Raleigh, NC, USA
2 W. M. Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC, USA
3 Department of Biology, North Carolina State University, Raleigh, NC, USA
4 Laboratory of Developmental Genetics, VIB-PRJ8 & Katholieke Universiteit Leuven, Center for Human Genetics, Leuven, Belgium
5 Current address: Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Department of Psychiatry, Richmond, VA, USA
BMC Biology 2009, 7:29 doi:10.1186/1741-7007-7-29Published: 11 June 2009
Additional files
Additional file 1:
Mean aggression scores (MAS) of 170 P{GT1} insert lines. This file shows the results of the screen of 170 P-element insert lines for alterations in aggressive behavior, the genes tagged by the P-elements, the mean aggression scores and effects, and gene ontology information.
Format: XLS Size: 57KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 2:
Human diseases associated with P{GT1} insertions in Drosophila genes with aberrant aggressive behavior. This file shows the P-element insert lines with altered aggressive behavior, their mean aggression scores, and diseases in which the human orthologues of the tagged genes have been implicated.
Format: XLS Size: 34KB Download file
This file can be viewed with: Microsoft Excel Viewer


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|Michael Parkinson
|Himself - Host / ... (295 episodes, 1971-2007)
Series Directed by
|Stuart McDonald
|(6 episodes, 1998-2007)
Series Produced by
|Beatrice Ballard
|executive producer (102 episodes, 1998-2004)
|Richard Drewitt
|producer (2 episodes, 1975-1976)
|John Fisher
|producer (2 episodes, 1978)
|Danny Dignan
|assistant producer / producer (2 episodes, 1998-1999)
|Steven Lappin
|producer (2 episodes, 2004-2007)
|Mark Wells
|executive producer (2 episodes, 2004-2007)
Series Original Music by
|Harry Stoneham
|(1 episode, 1975)
Series Film Editing by
|John Sillitto
|(2 episodes, 1982-2003)
|Chris Wadsworth
|(2 episodes, 1998-1999)
Series Production Design by
|Louise Lusby
|(3 episodes, 1971)
|Simon Kimmel
|(2 episodes, 1998-1999)
Series Costume Design by
|Lynda Wood
|(2 episodes, 1998-1999)
Series Makeup Department
|Christina Baker
|makeup designer (2 episodes, 1998-1999)
Series Production Management
|Garrie Mallen
|production manager (1 episode, 1998)
|Stephen Abrahams
|production manager (1 episode, 1999)
Series Art Department
|Bernard Heyes
|graphic designer / title sequence (2 episodes, 1998-1999)
|Bob Warans
|production buyer (2 episodes, 1998-1999)
Series Sound Department
|Tony Revell
|sound supervisor (2 episodes, 1998-1999)
Series Camera and Electrical Department
|Joe Finan
|camera operator (17 episodes, 2005)
|Nigel Saunders
|camera supervisor (2 episodes, 1998-1999)
Series Editorial Department
|Ian Trill
|vision mixer (2 episodes, 1998-1999)
Series Music Department
|Laurie Holloway
|musical director (2 episodes, 1998-1999)
Series Other crew
|Bill Cole
|resources manager / studio resources manager (78 episodes, 1998-2004)
|Chris Greenwood
|program consultant (2 episodes, 1998-1999)
|Quentin Mann
|floor manager (2 episodes, 1998-1999)
|Joanna MacDonnell
|floor manager (unknown episodes)
Series Thanks
|Anthony Morris
|acknowledgment: film extracts courtesy of (1 episode, 1975)
ITV obviously bares a grudge against the BBC. The loss of the
Premiership must still be fresh in the mind; why else would Parkinson
air before Match Of The Day? As ruthless as it may sound, they're
cunningly boring the audience to sleep.
Michael Parkinson has been peddling the same inoffensive, tired format for years now, and last nights episode was no exception. Guests included "the evergreen" Goldie Hawn, "the king of cool" John Travolta and, erm, "political correspondant" John Sergeant. 'Parky's golden rule is set out nice and clear from the outset: the bigger the star, the bigger the brown nosing.
He has neither the 'blokey' charm of Frank Skinner nor the wit of Jonathon Ross, but has somehow managed to remain increasingly popular throughout the years.
Unsurprisingly enough, Hawn was given an easy ride as far as questions go. Parkinson beamed on about her "glittering, successful career," clearly not having done his research. The fact remains that Hawn has not had a hit movie in nearly ten years. Her career is littered with far more misses than hits, but the way the he rambled on was like she'd won several Oscars. But she hasn't, and never will.
Next in the interviewee's chair was John Sergeant. Like Hawn, he too had a book to promote. This time though, it was about Margaret Thatcher. Sergeant claimed that with this book he "aimed to bring together the people who loved her and those who hated her." Parkinson agreed, but then again he would do. Hawn laughed uncontrollably at Sergeants mildly amusing political jokes, with one clear motive in her head: to make the audience believe that not all blondes are dumb.
John Travolta then took to the stage for his relentless barrage of lacklustre questioning. During his gruelling stint he was asked ridiculous questions such as "how do you manage to keep your feet on the ground?" This of course, was to a man, who, has two 747's parked in the driveway of his 60 acre mansion, and commands a $20 million fee for each film he's in. At one stage, Travolta told the story of the time he danced with Princess Diana - "I was told it was one of the highlights of her life" he beamed, "and one of mine too" he responded a good ten seconds later. At which point every middle aged housewife in Great Britain must of gone "Aw he's a lovely man." Parkinson then, for the first time in nearly 45 minutes asked a daring question - "Is their anytime in your career that you would point out as your lowest?" ("We've all had them," said Parkinson, obviously referring to the infamous Ali interview that occurred shortly after the invention of the wheel). Travolta though was allowed to skate around the question by referring to a time his car broke down.
And then it was back to sitting on the fence again for Parkinson, a position he's become rather too comfortable with throughout his career.
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TV sets sail with Titanic anniversary specials
- "The Titanic with Len Goodman" (April 10 at 8 p.m. EDT on most PBS stations) examines the impact of the sinking on the thousands of affected families, part of the Titanic legacy that lives on in the victims' descendants. Len Goodman, best known as a judge on "Dancing With the Stars," has his own connection: Before he was a dancer, he was a welder in East London for the company that built Titanic, in Belfast, Northern Ireland. Goodman takes viewers on an exploration of the ship's 100-year legacy through the stories of the handpicked group of men who helped build Titanic and then died with it.
- "Why Ships Sink" (April 18 at 9 p.m. EDT on most PBS stations) is a "Nova" program that investigates the safety of current-day cruise ships, which keep getting bigger and bigger. Some engineers fear that these towering behemoths are dangerously unstable, and the recent tragedy of the Costa Concordia has raised new questions about their safety. "Nova" brings together marine engineering and safety experts to reconstruct the events that led to famous cruise disasters, including the ill-fated Concordia, the Sea Diamond and the Oceanos.
The Associated Press


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Sign Up for DealFlyer and get An Extra 30% OFF Select Items! Sign Up
Closeouts. A long, double strand of blushy rose quartz beads bring a feminine, textural beauty to any look, thanks to the varying sizes of stones and a shimmery pink bow at the nape of the neck.


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Guide To Philly's Farmers' Markets
Philadelphians can take their pick of delicious, local produce, dairy products and baked goods…even artisanal chocolate and natural beauty products!
Top Spots To Pick Your Own Summer Produce
To reawaken the gatherer in you, head to one of these local farms and get your hands dirty.
More Options Than Ever For The Gluten Free
May is National Celiac Disease Awareness Month and eating to stay healthy is easier than ever.
Local College Students Grow Produce To Help Feed Area Residents
Hope of Harvest is a program that puts food on the tables of area residents. Scott Smith, Assistant Farm Manager at Delaware Valley College in Doylestown says this year, the program is expected to grow more than 50,000 pounds of vegetables.
Grocery Store Worker Recovering After Being Stung By Scorpion
A Giant produce employee is recovering after he was bit by a scorpion while at work on Saturday.
After Slow Start, NJ Tomato Production Expected To Be Back On Track
Agricultural agent Wesley Kline, with the Rutgers Cooperative Extension of Cumberland County, says too much rain in the spring and early summer is to blame for delaying outdoor tomato harvest by a week or two.
New Jersey Farmers Do Best To Cope With Heavy Rain
We may be in the grips of another heat wave around here, but recent heavy rains in the region have proven to be troublesome to several South Jersey farmers.
Guide To Philadelphia's Farmers' Markets
With so many farmers' markets within the city and scattered throughout the suburbs, Philadelphians can take their pick of delicious, local produce, dairy products and baked goods…even artisinal chocolate!
Gov. Corbett Meets With Chilean Minister Of Agriculture In An Effort To Increase Trade
The Governor's meeting with Chilean officials is a follow up to the administration's trip to South America last month for the purpose of increasing trade between the regions.
Environmental Group Releases Annual 'Dirty Dozen' List Of Fruits And Vegetables
The list, which highlights the 12 fruits and vegetables that are most contaminated by pesticides, included an additional "Plus" category for the second year in a row.
Local Food Prices Remain Stable Despite Drought In Midwest
Produce prices in our area have been stable this summer and should remain stable until locally grown produce is gone.
Health: New Study Shows White Produce Linked To Reduction Of Strokes
White is the new healthy color, according to new research that says white produce can be life saving.


text:
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All Candlebox sales and all other event tickets are final.
Headlining band announced for 2015 Portuguese Feast
The Feast of the Blessed Sacrament is July 30-Aug. 2, and the planning committee recently announced the headlining band for this year. Candlebox! Visit www.portuguesefeast.com for more information. Here's the news release from the committee:.
and more »
Clay Center Dispatch
Cookie jar and candle box
Clay Center Dispatch
Riley Riggs made this cookie jar (left) that received a commendation by Fort Hals Sate University and Sophomore Lauren Lane made the "DC candle box" that received a blue ribbon at the NCKL art show.
Port Huron Times Herald
Starship, Sponge and Candlebox to headline Riverfest
Port Huron Times Herald
St. Clair – This city wasn't built on rock 'n' roll — but it will rock out on July 24 and 25. The national acts for St. Clair Riverfest are Starship with special guest Sponge on July 24 and Candlebox on July 25, said Joe Nieporte, one of the owners of Funfest ...
Get Out! Candlebox and Clutch with Mastodon play Pittsburgh
Get All Digital Access to the website, apps, e-edition, plus local delivery of the Sunday paper.Subscribe now. Subscription Required. Thank you for reading The Times. Thank you for reading the Times. A subscription is required to access this premium content.
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Check out Frontrow.com for all your tickets needs. We've got great sources for any event ranging from concert tickets to World Series tickets, Book of Mormon tickets, and Las Vegas show tickets. And don't forget the chance to score big on Broadway tickets and once in a lifetime events like the National Final Rodeo, the 2016 Super Bowl or the Daytona 500. Our inventory covers all types of entertainment and special events. With the biggest selection of concerts, sports, and theater tickets around, you can't go wrong with tickets from Frontrow.com.


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The installation is titled "The Waters Reglitterized" after an essay Henry Miller wrote for his friend Emil Schnellock about painting, in 1949. Miller writes about doing one of his watercolors, "before going out to the cinema, I gave the smaller picture a bath. Astonishing effect -- everything took on a supernal hue, as at a dawn. Where the colors washed out completely it was not just white paper but a windswept space in which the vanished colors still spoke faintly."
©2015 Artnet Worldwide Corporation. All Rights Reserved.


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'The genius of France triumphant, - or - Britannia petitioning for peace'
20 of 45 portraits of Charles Stanhope, 3rd Earl Stanhope
© National Portrait Gallery, London
'The genius of France triumphant, - or - Britannia petitioning for peace'
by James Gillray, published by Hannah Humphrey
hand-coloured etching and aquatint, published 2 February 1795
10 x 14 1/4 in. (254 mm x 362 mm) paper size
Purchased, 1947
Reference Collection
Click on the links below to find out more:
Sittersback to top
- Charles James Fox (1749-1806), Whig statesman. Sitter associated with 298 portraits.
- Richard Brinsley Sheridan (1751-1816), Dramatist and parliamentary orator. Sitter associated with 162 portraits.
- Charles Stanhope, 3rd Earl Stanhope (1753-1816), Scientist and politician; MP for Wycombe. Sitter associated with 45 portraits.
Artistsback to top
- James Gillray (1756-1815), Caricaturist. Artist associated with 881 portraits, Sitter in 7 portraits.
- Hannah Humphrey (active 1778-1822), Publisher and printseller. Artist associated with 718 portraits, Sitter in 1 portrait.


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