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Bladder Infection Center - Grand Junction, CO
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Grand Junction, Colorado
Bladder Infection (Cystitis)
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Bladder infection is an infection of the bladder. Bladder infection is also called cystitis and is a type of urinary tract infection (UTI). The urinary tract is naturally sterile and when microbes invade it, ...
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Days of Blood & Starlight (Daughter of Smoke and Bone) (original 2012; edition 2012)
by Laini Taylor
Work details
Days of Blood and Starlight by Laini Taylor (2012)
No current Talk conversations about this book.
The end of Daughter of Smoke and Bone let us -- and its characters -- in on some secrets. Days of Blood and Starlight is what happens once those secrets are revealed.
I have to be honest and say that I almost wasn't going to review this title. Something about it just did not click with me. I did love Daughter of Smoke & Bone -- yet my least favorite part was the Karou and Akiva relationship (for whatever reason, one I could not pinpoint) and that is so much a basis for this book. Don't hate me yet for still choosing to review this!
The reason I am reviewing it despite the disconnect I felt from it is because of the movie news. (Still don't hate!)
There's something about both Daughter of Smoke & Bone and Days of Blood and Starlight, as well that fall back to more of a storytelling time. Days was better for me as an audiobook, hearing someone tell me the story, brought me into it a bit more.
I think what I missed -- and part of why I'm so hopeful the movie will happen soon -- in Days was the gorgeous, exquisite world Laini Taylor created in Daughter. It reminded me a lot of if Sara Crewe from the Little Princess movie had grown up in the magical world she imagined -- and dyed her hair blue.
I did love that some of my favorite characters, like Zuzana were back in this second book. I love that human marionette ballerina -- and her friendship with Karou. As always Laini Taylor's writing is fantastic and she always has lines I'm ready to quote. It just didn't all add up to a story that's so far (see #4 below) worked for me.
So, what I'm taking forever to say is this, no, I never did really connect with Days of Blood & Starlight (I hate that!), but four things: 1) Don't let that discourage you from trying either book 2) Try the audiobook(s) for this series 3) This book/series should be crazy brilliant as a movie, if adapted well - read the book(s) so you know what's up 4) I loved Daughter of Smoke & Bone so much I'm giving this one a try again later to see if I just read it at the wrong time.
(This may be my least sense-ical and/or logical review in a long, long time if not ever . . . . hoping my four points help a bit!)
(egalley received via NetGalley from LBYR; review originally posted on my blog)
It was good! I thought it was much better than the 1st in the series... I liked that there was more happening and less of the mindless mushy gushy love stuff.... (I mean, it is definitely also a love story, but the first one just felt kind of eyes-glaze-over dull, and this was much more interesting). I agree w/ one reviewer that this book probably makes light of genocide-type behavior when compared with the relationship woes... but if you read it as a fantasy (which I did) and not a commentary on real-life tragedies, and take it as a teen romance (which I did), I think you can move right past that ;) I'm looking forward to reading the 3rd!
Even though the story unravelled in a VERY SLOW pace, boring me out of my mind at times and confusing me about where the said story is supposed to be going, after reading Days of Blood & Starlight from cover to cover, I started to appreciate it for its darkness and twistedness. Those of us watching Supernatural have known for years that angels are not fun (Cas is, of course, a different kettle of fish), but here they are REALLY NOT FUN AT ALL. Having the most interesting characters being human says a lot about human race. And even though I like Apocalypse stories as much as the next girl, I really hope this one will not take the oh-my-god-we-are-all-going-to-die-and-the-supervillain-is-going-to-rule-the-world-and-we-have-to-have-the-end-of-the-world-party direction. If it does it is going to be a very boring series finale, which I am going to read anyway, obviously, because right now the story is going places.
I hate to start out with the negative but I've got to lay thoughts out as they come to me. The first third of this book seemed like a mountain climb that was mostly unnecessary. The second third was much more interesting, and the last third the story finally came alive.
Akiva and Karou are an emotional roller coaster all on their own, add in the other angels, chimera and humans and we almost have an emotional explosion. I felt so much closer to Zuzana and Mik this go round. Such a sweet couple and such good friends. Our new love to hate character turned out to be quite a surprise, much like our old love to hate character. These are the things that kept me hanging on.
I'm overall very satisfied with the read and am very excited for the next chapter in the story. Stars 3.5
I find no words to describe the beauty of this book.
I loved the way it went from one POV to another. I got to know the characters, their personalities, their thoughts, their fears and their hopes. They are so many and yet by the end of the book you could name each one of them. My heart broke so many times. This book described the awfulness of war, the loss each side feels be cause they had to follow a "leader" they don't agree with. Then the thoughts of uprising, the doubt, the HOPE.
I can't wait to start the third book.
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"The otherworldly Karou struggles to come to terms with who and what she is, and how far she'll go to avenge her people"--
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Overview of content related to 'interoperability'
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Interoperability is a property referring to the ability of diverse systems and organizations to work together (inter-operate). The term is often used in a technical systems engineering sense, or alternatively in a broad sense, taking into account social, political, and organizational factors that impact system to system performance.The IEEE Glossary defines interoperability as: the ability of two or more systems or components to exchange information and to use the information that has been exchanged. (Excerpt from Wikipedia article: Interoperability)
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EuroCAMP 2005
Masha Garibyan and Ann Borda report on the first Campus Architecture Middleware Planning workshop in Europe hosted by the Politecnico di Torino.
April 2005, issue43, event report
eResearch Australasia 2008
Tobias Blanke, Ann Borda, Gaby Bright and Bridget Soulsby report on the annual eResearch Australasia Conference, held in Melbourne, Australia, 29 September - 3 October, 2008.
October 2008, issue57, event report


text:
A delivery system (10) is disclosed for delivering a fluid-sensitive beneficial agent (7) such as a somatotropin, or an analogue or derivative thereof, to an animal such as a bovine. The delivery system comprises a wall that surrounds an internal compartment, said wall comprising a first wall section that limits the passage of fluid into the system and a second wall section that permits the passage of fluid into the system. An exit passageway is provided for delivering the beneficial agent an interior compartment (18) to the animal. The exit passageway is sealed with a wax seal (30) which is expelled through the passageway (13) as the internal pressure within the device (10) reaches a predetermined "bursting" pressure. The passageway (13) is preferably sized to compensate for slight variations in the efflux of the beneficial agent and to maintaining a sufficient volumetric outflow rate of beneficial agent in order to minimize influx of biological fluids from the external environment back into the device once the seal (30) is expelled.
1. A device for delivering a beneficial agent to a fluid environment of use, the device comprising:
a) a housing comprising a fluid impermeable wall section, the housing containing the beneficial agent;
b) an exit passageway for fluidly connecting the housing interior to the environment of use;
c) an energy source for increasing pressure within the housing when the device is in the environment of use;
d) a sealing material, adjacent the exit passageway, the material being effective to seal the exit passageway before the housing is pressurized, at least a portion of the material being expelled through the passageway after the housing is pressurized, thereby opening the exit passageway, thereafter allowing continuous release of a therapeutically effective amount of beneficial agent during the entire time of delivery.
2. The device of claim 1, wherein the energy source comprises an osmotic driver.
3. The device of claim 1, wherein the sealing material comprises a wax.
4. The device of claim 3, wherein the wax is a microcrystalline petroleum wax.
5. The device of claim 3, wherein the wax is a blend of a plurality of different waxes.
6. The device of claim 5, wherein the different waxes have differing hardnesses.
7. The device of claim 1, wherein the sealing material maintains the exit passageway sealed until the pressure generated by the energy source exceeds a predetermined pressure.
8. The device of claim 7, wherein the predetermined pressure is between about 0.4 and 0.7 kg/cm2.
9. The device of claim 1, wherein the exit passageway has a diameter of about 0.25 to 0.55 mm.
10. The device of claim 1, wherein the exit passageway has a length of about 1.5 to 3.5 mm.
11. A method of making a device according to claim 1, comprising:
sealing the exit passageway with a material which is expelled through the passageway when the housing is pressurized to a predetermined pressure level in order to open the exit passageway thereafter allowing continuous release of a therapeutically effective amount of beneficial agent during the entire time of delivery.
12. The method of claim 11, including increasing pressure within the housing by means of an osmotic driver.
13. The method of claim 11, wherein the sealing material comprises a wax.
14. The method of claim 13, wherein the wax is a microcrystalline petroleum wax.
15. The method of claim 13, wherein the wax is a blend of a plurality of different waxes.
16. The method of claim 15, wherein the different waxes have differing hardnesses.
17. The method of claim 11, including maintaining the exit passageway sealed until the pressure generated by the energy source exceeds a predetermined pressure.
18. The method of claim 17, wherein the predetermined pressure is between about 0.4 and 0.7 kg/cm2.
19. The method of claim 11, wherein the exit passageway has a diameter of about 0.25 to 0.55 mm.
20. The method of claim 11, wherein the exit passageway has a length of about 1.5 to 3.5 mm.
This invention relates to a beneficial agent (eg, a drug) delivery system, such as an implantable osmotically driven delivery system, and more particularly, the invention relates to a device that protects and administers a fluid-sensitive beneficial agent to a fluid environment of use.
Delivery devices for administering a beneficial agent to a biological, fluid environment of use are known to the prior art. See, for example, U.S. Pat. Nos. 5,137,727; 5,174,999; and 5,238,687.
These devices comprise a housing including fluid-impermeable first wall section and a fluid permeable second wall section. A beneficial agent is enclosed within the first wall section. An expandable driving member is enclosed within the second wall section. A slidable piston separates the beneficial agent from the expandable driving member. An exit passageway is formed in the fluid impermeable wall section. As fluid is imbibed through the semipermeable wall section, the driving member expands within the housing, pushing the slidable piston which forces the beneficial agent through the exit passageway.
The delivery devices described in the above patents operate successfully for their intended use and they can deliver many beneficial agents for their intended effects. Now, it has been observed that their use can be limited because difficulties associated with these delivery devices which include beneficial agents that are sensitive to biological fluids and to fluids containing biological gases; uneven delivery of those beneficial agents from the device and difficulties associated with shortening the start-up time for delivering the beneficial agents from the device.
Implanted devices are continually exposed to biological fluids naturally present in the body. Many beneficial agents, including proteins, peptides, and hormones, may be degraded (e.g., hydrolyzed) or diluted by fluids that enter the implanted device during operation thereof. The fluids may contact the agents by entering through the exit passageway, through the wall joints, or around the slidable piston. In addition, the delivery of beneficial agents from these devices may be uneven. Bubbles may impede passage of the agents through the exit passageways. Pressure may be created by differential expansion between the agent formulation and the materials used to construct the device altering the actual agent delivery rate. Furthermore, the disclosed devices may be unable to provide the desired delivery rates and start-up times.
Thus, there is a need for a delivery system for administering a drug or other beneficial agent that is sensitive to aqueous biological fluids at a controlled rate and for protecting the beneficial agent, and which delivery device possesses the ability to continually deliver the protected beneficial agent in effective amounts, over the desired time, particularly in the fields of human and veterinary medicine (eg, in the breeding and management of farm animals).
The present invention is directed to a fluid-imbibing delivery device or dispenser for storing and protecting a fluid-sensitive beneficial agent and for dispensing the beneficial agent to a fluid environment of use over a prolonged period of time. Protecting the beneficial agent reduces the evaporation of fluid from a beneficial agent solution and/or the dilution or degradation of the beneficial agent by the influx of fluid from the environment of use, thereby maintaining its efficacy.
In accordance with one aspect of the present invention, the delivery device is provided with a sealed exit passageway to protect the beneficial agent from the ingress of biological fluid from the environment of use. The sealed passageway opens once a predetermined internal pressure has been achieved after placing the delivery device in the environment of use. Once the exit passageway has been opened, the agent in the device is isolated from the biological fluid diffusing in through the exit passageway by means of outflow of the beneficial agent at a sufficient rate to prevent the influx of biological fluid from the environment of use. This is achieved by providing sufficient volumetric efflux of the beneficial agent formulation which is pumped into the evironment of use. The volumetric flow of the beneficial agent formulation from the device is a function of the internal osmotic pressure generated by the expandable osmotic driver and by the size (ie, cross-sectional area) of the exit passageway. In addition, the passageway preferably has an extended length which is sufficient to prevent biological fluids in the environment of use from diffusing into the compartment enclosing the beneficial agent when the efflux is temporarily halted, e.g., when the partition movement is impeded.
The drawing figures, which are not drawn to scale, and wherein like reference numerals refer to like elements, are set forth to illustrate various embodiments of the invention as follows:
FIG. 1 is a cross-sectional view of one embodiment of the delivery device of the invention, illustrating one structural embodiment of the delivery system comprising a first walled section and a second walled section.
FIG. 2 is an enlarged fragmented cross-sectional view of the mating end cap of FIG. 1.
FIG. 3 is a graph showing the time (hours) needed to burst a wax seal of the type shown in FIGS. 1 and 2 at various internal pressures.
FIG. 4 is a graph showing the effect of exit passageway diameter on water ingress, measured as percent dilution of a beneficial agent formulation.
FIG. 5 is a graph of internal bursting pressure versus wax seal thickness for a preferred wax seal in accordance with the present invention.
FIG. 6 is a graph of internal bursting pressure for various mixed wax seals in accordance with the present invention.
FIG. 1 illustrates one embodiment of the delivery device according to the present invention. Delivery system 10 of FIG. 1 comprises a housing 11 formed of a wall 12, which wall comprises a first wall section 12a and a second wall section 12b. Wall 12 encloses and defines an internal compartment 18. Delivery system 10 has at least one exit passageway 13 for delivering a beneficial agent formulation 7 from delivery system 10, the inlet of which is in continuous contact with the beneficial agent during storage and use. In accordance with the present invention, the exit passageway 13 is initially sealed with a wax seal 30, discussed below, a portion of which is discharged out through passageway 13 when the pressure within compartment 18 rises above a predetermined bursting pressure during operation of device 10.
Wall section 12a may be in the form of a tubular member having a first and a second open ends 32 and 34, respectively. In this particular embodiment, an end cap 36 is positioned on first wall section 12a at its lead end 9.
The device 10 isolates the beneficial agent from exposure to environment fluids diffusing into the compartment 18 defined by the first wall section 12a. First wall section 12a encloses and defines the internal space of compartment 18 initially occupied by the beneficial agent 7. First wall section 12a also comprises a composition that is substantially impermeable to the exchange of fluid, beneficial agent 7 and other ingredients contained in delivery system 10. The phrase substantially impermeable, as used herein, indicates the volume of external fluid passing through the first wall section 12a is substantially negligible, that is, about zero up to about 1μ or up to about 1 mL/day. As a result, wall section 12a serves as a means for substantially protecting a beneficial agent 7 that is sensitive to exterior fluid present in the environment of use. Other representative compositions for forming first section 12a such as vinylidene chloride copolymers and terpolymers, acrylonitrile polymers, halogenated polymers and polycarbonates are discussed in U.S. Pat. No. 5,057,318, incorporated by reference herein.
Wall section 12b surrounds that portion of internal compartment area 18 that contains expanding means 25 for expanding and for occupying space in compartment 18 for delivery of a beneficial agent formulation from delivery system 10. Wall section 12b has an open end 40 and an enclosed end 42, the enclosed end at end 8 and the open end distal therefrom. Second wall section 12b is permeable to the passage of fluid and it is substantially impermeable to the passage of other ingredients contained in delivery system 10. The thickness and the surface area of the second wall section 12b contribute to the rate of passage of fluid through the membrane second wall section. The rate of passage is a function of thickness, the surface area, the particular compound used in forming the membrane cup and the particular expandable driving means. Thus, a desired fluid flow rate of fluid from the environment of use into the delivery device of about 10-15 μgm H2 0/day and more particularly about 12-14 μgm H2 0/day can be achieved by manipulation of the above described factors.
Typical semipermeable materials, flux enhancers and plasticizers for forming wall 12b are known in the art, and are described in detail in U.S. Pat. No. 5,057,318.
Referring again to FIG. 1, compartment 18 comprises a beneficial agent formulation 7, which beneficial agent formulation 7 comprises a beneficial agent 7a, identified by dots, and a pharmaceutically acceptable carder 21, identified by wavy lines. The pharmaceutically acceptable carder may include more than one ingredient, such as a buffer 22, identified by horizontal dashes; a pharmaceutically acceptable vehicle 23, identified by vertical lines; a pharmaceutically acceptable surfactant 24, identified by slanted lines; and other formulation ingredients, as are known in the art. Delivery device 10 in its compartment 18 can also comprise pharmaceutical carder 21. Carder 21 may optionally include viscosity modulating vehicles (23), buffers (22), surfactants (24), dyes, and other additives known in the art, examples of which are disclosed in U.S. Pat. Nos. 5,034,229 and 5,135,123 to comprise the beneficial agent formulation 7.
One class of fluid-sensitive agents that are presently preferred for delivery from the devices of the present invention are growth factors, including bovine somatotropin and analogues and derivatives thereof. The devices of the present invention provide a means for delivering an effective amount of a beneficial agent for causing increased productivity, such as, in the case of the somatotropins, a higher feed conversion efficiency, improved carcass quality, higher than normal rate of animal weight gain, and increased milk production. Most preferably the bovine somatotropin is present in an amount of about 25 to 60 wt % of the beneficial agent formulation 7, preferably about 30 to 45 wt %.
Wall section 12b surrounds, an expanding means 25 optionally comprising members 25a-f. Expanding means 25 expands in response to fluid imbibed across wall 12b and optionally comprises an osmagent homogeneously or heterogeneously blended with binder.
The expandable driving means 25, initially surrounded by second wall section 12b and operable for pushing the beneficial agent formulation 20 from delivery device 10 comprises, in a presently preferred embodiment, an osmopolymer. The expandable driving means 25 in another preferred embodiment comprises an osmagent. The expandable driving means 25 yet in another preferred embodiment comprises an optional osmagent dispersed within the osmopolymer. Osmagents and osmopolymers are known to the art in U.S. Pat. Nos. 3,865,108; 4,002,173; 4,207,893; 4,327,725; 4,612,008; 5,034,229 and 5,135,123 for example, the disclosures of which are incorporated by reference herein.
In a presently preferred embodiment, delivery device 10 comprises a plurality of expandable driving means 25a-f initially housed in second wall section 12b. This configuration is merely illustrative and there may be any number of driving means present. Generally, there are from one to six expandable driving means; however, this number is not controlling. The expandable driving members in a presently preferred embodiment are formed as depots or layers and comprise like or unlike compositions. For example, driving means 25a-f can be made as tablets comprising like osmopolymers or like osmagents, or they can comprise unlike osmopolymers or unlike osmagents, or one or more of the members can be a composition comprising an osmopolymer together with an osmagent.
Formed on the outer surface 52 of the wall section 12b is the second smoothing shoulder 46. Second smoothing shoulder 46 is positioned to co-extend with the second open end 34 of the first wall section 12a when the second wall section is telescoping received within the first wall section. External discontinuities or surface fiction of the implant device are this minimized and provide a smooth transition between the first and second wall sections. In this particular embodiment, the portion of the second wall section 12b inserted within the first wall section 12a has the same thickness as that portion outside the first wall section. In addition, as a result of this construction, the inside surface of the first and second wall sections facilitates the travel of the piston along the formed smooth continuous interior surface.
In addition, end cap 35, best illustrated in FIG. 2, provides a means for simply and conveniently assembling the device of the invention, and particularly for filling the device with internal components such as the osmotic driver, the partition and the beneficial agent formulation. The end cap 38 is substantially impermeable to fluid, providing protection for the fluid-sensitive beneficial agent. Materials for forming end cap 38 may be chosen from those materials useful in preparing impermeable first wall section 12a. The end cap 38 is specifically beneficial when delivering fluid sensitive materials and protects the material to be delivered before and after activation of the device.
End cap 38 includes an exterior cap side 70, an interior end cap side 72 and an exit passageway 13 extending from the external environment 41 into internal chamber 18 containing formulation 7. The endcap 35 isolates the beneficial agent by providing an adequate formulation flow rate, driven by fluid swellable driving means 25 and a partition member 27 including piston 29, to prevent dilution of the formulation in chamber 18 by the inflow of fluids from the external environment 41. The exit passageway 13 is sized in diameter and length to provide a sufficient beneficial agent formulation efflux which any biological fluid present in the external environment to flow through passageway 13 and into the interior of device 10.
The diameter of the exit passageway 13 determines the volumetric outward flow of the beneficial agent 7 from the internal compartment 18. The length of the exit passageway 13 provides a means for compensating for slight variations in the efflux of the beneficial agent. A passageway diameter of about 0.25 to 0.55 mm, preferably about 0.4 mm, is generally sufficient to generate a sufficient outward volumetric flow of the beneficial agent. A passageway length of about 1.5 to 3.5 mm, preferably about 2.5 mm, is sufficient to compensate for slight variations in the efflux of the beneficial agent.
The terms "exit means" and "exit passageway", as used herein, comprise means and methods suitable for the metered release of the beneficial agent 7 from compartment 18 of delivery device 10. This includes maintaining sufficient efflux or outward volumetric flow of the beneficial agent to prevent an inward flow of biological fluid from the external environment and prevent contact with the beneficial agent formulation in the compartment 18. The exit passageway includes at least one passageway, orifice, or the like, through first wall section 12a or the end cap 38 for establishing fluid communication between compartment 18 and the external environment of use 41. The passageway 13 can have any cross-sectional shape such as round, triangular, square, elliptical, and the like, but preferably is roughly circular, for assisting in the metered release of beneficial agent from delivery device 10. Delivery device 10 can be constructed with multiple passageways 13 in spaced-apart relation. Passageways and materials, equipment and methods for forming passageways are disclosed in U.S. Pat. No. 5,034,229.
Seal 30 blocks the exit passageway 13 until a pre-determined bursting pressure is reached within the device. A recess 37 is preferably provided in end cap 30 so that the wax 30 can be placed therein while in a molten state. Using this procedure, the wax seal 30 will generally fill substantially the entire volume of the exit passageway 13. The internal seal 30 provides point of use readiness without having to reopen the device, such as with a break-off tab, provides for a long term stability seal, protects formulation at start-up and has a consistent rupture pressure to provide consistent start-up. In addition, since the exit passageway 13 is occluded until the pre-determined pressure is reached, the beneficial agent is isolated within the internal compartment 18. Furthermore, when the pressure is sufficient to expel the plug of wax within passageway 13, the osmotic energy source provides sufficient pressure against piston 29 to ensure continuous pumping of the beneficial agent formulation once the plug seal has been burst.
This seal 30 serves several purposes. First, seal 30 seals exit passageway 13 to prevent premature delivery of a beneficial agent 7 from delivery device 10 and to prevent evaporation of volatile carder components such as water or other solvents during storage. By sealing passageway 13, seal 30 helps maintain the clean or optionally sterile environment inside delivery device 10, thereby protecting the materials inside the delivery device from oxidation and also protects the beneficial agent formulation from dilution by body fluids following implantation. The release of the seal 30 occurs when the pressure generated within the device is greater than the burst pressure of the seal. Those skilled in the ad will recognize this must necessarily exceed the pressure outside the device in the environment of use.
In one embodiment, the seal 30 is comprised of a wax. Mineral, vegetable, plant, animal, petroleum and synthetic waxes may be used. Preferably, the wax is a synthetic or refined wax, as opposed to a natural source wax (eg, beeswax), as these are more consistant in composition and physical propedies. More preferably, the wax is a microcrystalline petroleum wax. Preferred waxes are said by Witco of Greenwich, Conn. under the tradnames Multiwax X145a and 180-M. Most preferred is a mix of these two grades of wax. Using these waxes consistent bursting pressures for the seal 30 in end cap 38 have been achieved. Although the invention is not limited to any particular range of bursting pressure, using wax based seals, bursting pressures of about 0.4 to 0.7 kg/cm2 (gauge) are typical.
When wax is utilized as the material of seal 30, the bursting pressure of the seal 30 can easily be modified by varying the thickness of the seal or the hardness of the wax. The thickness can be altered by varying the depth of the recess 37 or the amount of wax in recess 37. The hardness of the wax can be modified by varying the percent composition of a combination of hard and soft microcrystalline waxes as shown in FIGS. 5 and 6. Other waxes which can be used to form seal 30 include montan wax, ozokerite wax, carnuba wax, myricyl cerotate wax, beeswax, parafin wax, spermaceti, ceresine, gamma wax, Japan wax, ouricury, ceresin wax and castor wax.
There are limitations on the maximum strength of the seal 30 determined by the amount of pressure the expandable driving member can generate at start-up without exceeding the yield strength of the second semipermeable wall section 12B. If the force to expel the seal 30 exceeds this yield strength then failure at the joint between the wall portions 12a and 12b can occur, which can result in system failure.
Delivery device 10 can be implanted into the peritoneal cavity of an animal (eg, a human) using a conventional implanting apparatus. Generally, an implanter comprises a tubular member with a central longitudinal axial bore, a pointed, elongated, annular concavely beveled implanting end and an implant-charging end. The implanting end and the charging end communicate through a bore. A plunger adapted to be removably inserted in the bore is designed for slidable movement therein for applying the necessary force for implanting the implant. Alternatively, the implant can be surgically or subcutaneously implanted in the peritoneal cavity.
Delivery device 10 can be manufactured by standard manufacturing techniques. In one process, the first wall section 12a and the second wall section 12b are independently injection molded or extruded into the desired shape. Then, the first wall section 12a is filled with the beneficial agent composition. The second wall section 12b is filled with an expandable driving member or members, and the piston 29 is next added thereto in layered arrangement. Optionally, the piston 29 may be added to the first wall section 12a after filling the wall section with beneficial agent, in addition to, or instead of, the partition layer added to second wall section 12b. Next, the two sections at their open ends are slid together.
The delivery device of the present invention can be manufactured for delivering numerous beneficial agents, including drugs, at a controlled rate to a presently preferred biological environment of use such as warm-blooded animals, including humans; ruminants, such as bovines and sheep; porcines, such as hogs and swine; horses; and the like. The delivery devices provide for high loading of a beneficial agent and for its improved delivery in beneficially effective amounts (that is, amounts that provide a beneficial effect) over time. It is to be understood that the delivery devices can take a wide variety of shapes, sizes and forms adapted for delivering beneficial agents to environments of use. For example, the devices manufactured as delivery devices can be used for dispensing a beneficial agent in the anal-rectal passageway, in the cervical canal, as an artificial gland, in the vagina, as a subcutaneous or intraperitoneal implant, and the like. The delivery devices can be used in hospitals, nursing homes, outpatient clinics, sickrooms, veterinary clinics, farms, zoos, and other environments of use.
FIG. 5 is a graph depicting the internal bursting pressure for a "mixed" wax seals comprising 50% Multiwax 180-M and 50% Multiwax X-145a, the seals having thicknesses between 1.3 and 2.5 mm, from exit passageways having a diameter of 0.4 mm and a length of 2.54 mm. The bursting pressure for those seals having a thickness of 1.3 mm was consistently about 1.6 kg/cm2.
Thus, an exit passage having a 0.4 mm diameter and a length of 2.5 mm, in fluid contact or abutted by a seal of 1.3 mm thick, bursts the seal at about 1.6 kg/cm2 (gauge).
FIG. 3 is a graph showing the effect of the exit passageway diameter on the diffusion of water using an exit passageway length of 2.5 mm and specified diameter. Empirical observations of the respective devices indicate that the beneficial agent formulation turned white in all devices with 1.3 mm diameter passageways with small pockets of water entrained in the formulation. The beneficial agent formulation was clear in all devices having an exit passageway diameter of about 0.4 mm.
Thus an exit aperture having a diameter of 0.4 mm provides sufficient outward volumetric flow or efflux of the beneficial agent from the compartment 18 to substantially prevent diffusion of external fluid back into the compartment 18.
The novel devices of this invention use means for the obtainment of precise release rates in a fluid environment of use while simultaneously maintaining the integrity of the device and the stability of the fluid-sensitive beneficial agent 7 within the device. While there has been described and pointed out features of the invention as applied to presently preferred embodiments, those skilled in the art will appreciate that various modifications, changes, additions and omissions in the devices illustrated and described can be made without departing from the spirit of the invention.
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Arista Black Vinyl Arm Chair
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Staff Profile
Career Summary
Since 2010, I have been employed as an academic statistician within the Priority Research Centre for Gender Health and Ageing (PRCGHA) at the University of Newcastle. I have been afforded the opportunity to work on research using data from the Australian Longitudinal Study of Women's Health (ALSWH), Australia's largest longitudinal study on women focussed on health and well-being. In 1996, this study recruited more than 40,000 women from three different cohorts (born 1921-1926, 1946-1951 and 1973-1978) and last year, ALSWH finalised the recruitment of over 15,000 women into a new cohort (born 1989-1995).
I have been involved with research relating to 1921-1926 cohort (topics: asthma; mental health; social functioning; hospitalisation with stroke and disabilities; constipation; faecal incontinence), as well as research relating to the 1973-1978 cohort (topics: perinatal mental health; alcohol consumption during pregnancy; intimate partner violence). I am involved with research using the 45 & Up Study, specifically the Social, Economic and Environmental Factors (SEEF) sub-study and the Life Histories and Health (LHH) sub-study. ). I currently supervise three PhD students and act as statistical advisor to another 5-8 other RHD students. I have successfully transitioned to public health research, actively contributing to the research output of the PRCGHA (ie. papers, reports, student supervision, etc). In recent years, this work has culminated in several publications and I am currently involved in the preparation of other manuscripts relating to the ALSWH data.
Prior to my appointment at the PRCGHA, I was employed as a statistician at the NHMRC Clinical Trials Centre (CTC), University of Sydney. During my time at the CTC, I was primarily involved in cardiovascular and oncology related research. Initially I was employed as a junior statistician, conducting analysis for the LIPID study. However, I became the senior statistician for the FIELD study in 2000. This trial was completed in 2005 and I coordinated the analysis for the final report and primary results paper. I was also involved with various cancer trials groups after 2005. I was the consultant statistician for the NSW Clinical Trials Partnership (an initiative between the CTC and the NSW Cancer Institute to promote clinical trials in cancer areas) and served as the group statistical advisor for trials within the Australasian Lung Cancer Trials Group (ALTG) operations committee. I was heavily involved with the teaching opportunities presented at the CTC, taking on a coordinator's role in 2003-2007 for many of the professional development courses offered by the CTC. I also participated in the delivery of several Masters level subjects offered within the School of Public Health.
I have been approached to serve on committees due to my knowledge in study design, research methodology and statistical analysis. I currently serve on the International Data and Safety Monitoring Committee (ISDMC) for two clinical trials and remain a member of the Trial Management Committee for another study. Although I left clinical trials work a number of years ago, I have been repeatedly invited back as a faculty member for the Australia & Asia Pacific Oncology Research Development (ACORD) Workshops, providing advice and support to workshop participants with respect to design, methodology and statistical issues.
I have been involved with securing funding for four studies, totally $3.7M over the past 10 years (NHMRC and multi-state Cancer Council grants).
- Master of Biostatistics, University of Sydney, 05/12/2005
- Master of Public Health, University of Queensland, 19/03/1999
- Bachelor of Science (Honours), Griffith University, 17/03/1995
- Bachelor of Science, Griffith University, 01/03/1993
Research keywords
- biostatistics
- clinical trials design
- cohort studies
- health research
- life course epidemiology
- longitudinal methods
- longitudinal studies
- population health
- research design
- research methodology
Research expertise
As a biostatistician, I have worked in a range of health research settings. I currently work within the Research Centre for Gender Health and Ageing at the University of Newcastle, and am involved with design and analysis of data from the Australian Longitudinal Study on Women's Health, a large-scale cohort study which is tracking the health and wellbeing of more than 55,000 Australian women. I also have extensive experience in the design and analysis of randomised clinical trials, having worked for 10 years in clinical trials in the areas of oncology, cardiovascular disease, diabetes and neonatal research.
I have expertise in biostatistics, epidemiology and research design.
- English
Fields of Research
|Public Health And Health Services
My primary work is involved with the Australian Longitudinal Study on Women's Health, contributing expertise on research design, methodology and longitudinal studies.
Teaching keywords
- Biostatistics
Teaching expertise
I currently supervise three PhD students and act as statistical advisor to 5-8 other RHD students. I have been involved with the teaching of biostatistics in Australia through the Biostatistical Collaboration of Australia (BCA), which is an advanced master's program in biostatistics, designed to address an Australia-wide shortage of biostatisticians. I have coordinated a master's level course on clinical trials methods for the Master of Public Health program at Sydney University, and have tutored biostatistics within the MPH and MClinEpi courses at Sydney University, as well as lectured within the Basic Sciences of Oncology program (Cancer Institute NSW).
For publications that are currently unpublished or in-press, details are shown in italics.
Click on a category title below to expand the list of citations for that specific category.
Journal article (33 outputs)
|Vo K, Forder PM, Tavener M, Rodgers B, Banks E, Bauman A, Byles JE, 'Retirement, age, gender and mental health: Findings from the 45 and Up Study', Aging and Mental Health, 19 647-657 (2015)
Co-authors: JULIE BYLES
|Majeed T, Forder P, Mishra G, Byles J, 'Women, Work, and Illness: A Longitudinal Analysis of Workforce Participation Patterns for Women Beyond Middle Age.', J Womens Health (Larchmt), (2015)
DOI: 10.1089/jwh.2014.5009 | Author URL
Co-authors: JULIE BYLES
|Byles JE, Leigh L, Vo K, Forder P, Curryer C, 'Life space and mental health: a study of older community-dwelling persons in Australia', AGING & MENTAL HEALTH, 19 98-106 (2015)
DOI: 10.1080/13607863.2014.917607 | Author URL
Co-authors: JULIE BYLES
|Baker J, Janda M, Gebski V, Forder P, Hogg R, Manolitsas T, Obermair A, 'Lower preoperative quality of life increases postoperative risk of adverse events in women with endometrial cancer: results from the LACE trial.', Gynecol Oncol, 137 102-105 (2015)
|Majeed T, Forder P, Mishra G, Kendig H, Byles J, 'A gendered approach to workforce participation patterns over the life course for an Australian baby boom cohort', Journal of Vocational Behavior, 87 108-122 (2015)
DOI: 10.1016/j.jvb.2014.12.004
Co-authors: JULIE BYLES
|Chojenta C, Harris S, Reilly N, Forder P, Austin M-P, Loxton D, 'History of pregnancy loss increases the risk of mental health problems in subsequent pregnancies but not in the postpartum', PLoS ONE, 9 (2014) [C1]
DOI: 10.1371/journal.pone.0095038
Co-authors: CATHERINE CHOJENTA, DEBORAH LOXTON
|Anderson AE, Hure AJ, Forder PM, Powers J, Kay-Lambkin FJ, Loxton DJ, 'Risky drinking patterns are being continued into pregnancy: a prospective cohort study.', PLoS One, 9 e86171 (2014) [C1]
DOI: 10.1371/journal.pone.0086171 | Author URL
Co-authors: ALEXIS HURE, AMY ANDERSON, DEBORAH LOXTON, JENNY POWERS, f kaylambkin
|Kendig H, Byles JE, O'Loughlin K, Nazroo JY, Mishra G, Noone J, et al., 'Adapting data collection methods in the Australian Life Histories and Health Survey: a retrospective life course study', BMJ OPEN, 4 (2014) [C1]
DOI: 10.1136/bmjopen-2013-004476 | Author URL
Co-authors: JULIE BYLES
|Reilly N, Harris S, Loxton D, Chojenta C, Forder P, Austin M-P, 'The impact of routine assessment of past or current mental health on help-seeking in the perinatal period', Women and Birth, (2014) [C1]
DOI: 10.1016/j.wombi.2014.07.003
Co-authors: CATHERINE CHOJENTA, DEBORAH LOXTON
|Vo K, Forder PM, Tavener M, Rodgers B, Banks E, Bauman A, Byles JE, 'Retirement, age, gender and mental health: findings from the 45 and Up Study', Aging and Mental Health, (2014)
Co-authors: JULIE BYLES, MEREDITH TAVENER
|Halland M, Koloski NA, Jones M, Byles J, Chiarelli P, Forder P, Talley NJ, 'Prevalence Correlates and Impact of Fecal Incontinence Among Older Women', DISEASES OF THE COLON & RECTUM, 56 1080-1086 (2013) [C1]
DOI: 10.1097/DCR.0b013e31829203a9 | Author URL
Co-authors: JULIE BYLES, NICHOLAS TALLEY, PAULINE CHIARELLI
|Anderson AE, Hure AJ, Forder P, Powers JR, Kay-Lambkin FJ, Loxton DJ, 'Predictors of antenatal alcohol use among Australian women: A prospective cohort study', BJOG: An International Journal of Obstetrics and Gynaecology, 120 1366-1374 (2013) [C1]
Co-authors: ALEXIS HURE, AMY ANDERSON, DEBORAH LOXTON, JENNY POWERS, f kaylambkin
|Loxton D, Powers J, Fitzgerald D, Forder P, Anderson A, Taft A, Hegarty K, 'The Community Composite Abuse Scale: Reliability and Validity of a Measure of Intimate Partner Violence in a Community Survey from the ALSWH', Journal of Women's Health, Issues & Care, 2 (2013) [C1]
Co-authors: AMY ANDERSON, DEBORAH LOXTON, JENNY POWERS
|Reilly N, Harris S, Loxton D, Chojenta C, Forder P, Milgrom J, Austin M, 'Disparities in reported psychosocial assessment across public and private maternity settings: a national survey of women in Australia', BMC Public Health, 13 632 (2013) [C1]
DOI: 10.1186/1471-2458-13-632 | Author URL
Co-authors: CATHERINE CHOJENTA, DEBORAH LOXTON
|Byles JE, Forder PM, Grulich A, Prestage G, '"It's okay to ask." Inclusion of sexual orientation questions is feasible in population health surveys', AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, 37 390-391 (2013) [C1]
DOI: 10.1111/1753-6405.12090 | Author URL
Co-authors: JULIE BYLES
|Reilly N, Harris S, Loxton D, Chojenta C, Forder P, Milgrom J, Austin M, 'Referral for Management of Emotional Health Issues During the Perinatal Period: Does Mental Health Assessment Make a Difference?', Birth, 40 297-306 (2013) [C1]
DOI: 10.1111/birt.12067 | Author URL
Co-authors: CATHERINE CHOJENTA, DEBORAH LOXTON
|Nair-Shalliker V, Fenech M, Forder PM, Clements MS, Armstrong BK, 'Sunlight and vitamin D affect DNA damage, cell division and cell death in human lymphocytes: A cross-sectional study in South Australia', Mutagenesis, 27 609-614 (2012) [C1]
|Fogarty G, Morton RL, Vardy J, Nowak AK, Mandel C, Forder PM, et al., 'Whole brain radiotherapy after local treatment of brain metastases in melanoma patients - a randomised phase III trial', BMC Cancer, 11 142 (2011) [C1]
|Show 30 more
Conference (4 outputs)
|Chojenta C, Loxton DJ, Lucke J, Forder P, 'A longitudinal analysis of the predictors and antecedents of postnatal depression in Australian women', Archives of Women's Mental Health, Paris, France (2013) [E3]
Co-authors: CATHERINE CHOJENTA, DEBORAH LOXTON
|Moores C, O'Callaghan N, Donoghoe M, Forder PM, Armstrong B, Fenech M, 'The effect of a micronutrient supplement on telomere length', Australasian Medical Journal, Queenstown, NZ (2011) [E3]
|Koloski NA, Jones M, Gill RS, Forder PM, Talley NJ, 'Long term risk factors for the development of constipation in older community dwelling women', Gastroenterology: DDW 2011 Abstracts, Chicago, IL (2011) [E3]
Co-authors: NICHOLAS TALLEY
|Halland M, Koloski NA, Jones M, Byles JE, Chiarelli PE, Forder PM, Talley NJ, 'Modifiable risk factors associated with faecal incontinence in older community dwelling women', Journal of Gastroenterology and Hepatology, Brisbane, Australia (2011) [E3]
DOI: 10.1111/j.1440-1746.2011.06826.x
Co-authors: JULIE BYLES, NICHOLAS TALLEY, PAULINE CHIARELLI
|Show 1 more
Grants and Funding
|Number of grants
|Total funding
Click on a grant title below to expand the full details for that specific grant.
2015 (1 grants)
House and Home: Pathways and alternatives to residential aged care for older Australian women$91,024
Funding Body: IRT (Illawarra Retirement Trust)
|Project Team
|Professor Julie Byles, Associate Professor Deirdre McLaughlin, Mrs Peta Forder, Associate Professor Deb Loxton
|Research Foundation Grant
|Total Amount
|Funding Start
|Funding Finish
Research Supervision
|Number of current supervisions
|Total current UoN PhD EFTSL
For supervisions undertaken at an institution other that the University of Newcastle, the institution name is listed below the program name.
Current Supervision
|Supervisor Type
|Research Title
|PhD (Gender & Health)
|Asthma Quality Care in Australian Older Women
|PhD (Gender & Health)
|Medications Use and Mental Health Outcome
|PhD (Gender & Health)
|Life-Course Impact of Chronic Diseases on Patterns of Workforce Participation: A Gendered Approach
Mrs Peta Forder
|Work Phone
|(02) 4042 0676
|Academic Statistician
Priority Research Centre for Gender, Health and Ageing
Faculty of Health and Medicine
The University of Newcastle, Australia
Workstation 114, Level 4, HMRI Building,
Hunter Medical Research Institute (John Hunter Hospital Campus),
John Hunter Hospital Campus


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JBT Corporation Announces Award of Citrus Processing Conversion Contract
CHICAGO, June 8 /PRNewswire-FirstCall/ — JBT Corporation (NYSE: JBT) announced today that its JBT FoodTech business has been awarded an exclusive contract in excess of $30 million for the supply of new citrus processing equipment to French group Louis Dreyfus Commodities. The six year operating lease agreement includes the conversion of all LD Commodities' (Dreyfus) Brazil and US-based citrus processing facilities to JBT FoodTech citrus juice extractors and associated ancillary equipment.
Dreyfus participates in a wide variety of businesses and commodities including the processing of citrus fruits, being one of the world's three largest orange juice processors. Dreyfus markets citrus juice produced in their Brazil and U.S. operations to over 70 countries throughout North America, Europe, Asia Pacific, the Middle East and Latin America.
"We are very pleased with our strengthened relationship with Dreyfus and Dreyfus' confidence in JBT's leading citrus processing technology and proven track record for field service and technical support," said Juan Podesta, Vice President and General Manager for JBT FoodTech's Food Processing Systems Division. "Throughout the last citrus season, JBT's technical team worked closely with Dreyfus to unequivocally demonstrate JBT's strong value streams. We will continue to work closely with the Dreyfus team to contribute to our customer's success in achieving the optimal mix of yield, quality, and throughput that the market demands."
The project will be phased in over the next three years with all Dreyfus facilities fully converted to JBT FoodTech citrus extractors by the second quarter of 2013.
JBT Corporation (NYSE: JBT) is a leading global technology solutions provider to the food processing and air transportation industries. JBT Corporation designs, manufactures, tests and services technologically sophisticated systems and products for regional and multi-national industrial food processing customers through its JBT FoodTech segment and for domestic and international air transportation customers through its JBT AeroTech segment. JBT Corporation employs approximately 3,300 people worldwide and operates sales, service, manufacturing and sourcing operations located in over 25 countries. For more information please visit www.jbtcorporation.com or www.jbtfoodtech.com.
This release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995. Forward-looking statements are information of a non-historical nature and are subject to risks and uncertainties that are beyond the Company's ability to control. These risks and uncertainties are described under the caption "Risk Factors" in the Company's Annual Report on Form 10-K filed by the Company with the Securities and Exchange Commission that may be accessed on the Company's website. The Company cautions shareholders and prospective investors that actual results may differ materially from those indicated by the forward-looking statements.
SOURCE JBT Corporation


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Microsoft and Crytek are enhancing the "Ryse: Son of Rome" experience with a free game update to Gladiator Mode that includes two new level events. In addition, the first add-on pack for Gladiator Mode, the Colosseum Pack, is available, adding two new character skins and two new arenas where you'll spill your foes' blood and grow your legacy.
New Arenas and Gladiator Skins Available with the Colosseum Pack
Available for NZD$5.85 through the Xbox Live Marketplace, or as part of the "Ryse: Son of Rome" Season Pass, the Colosseum Pack includes:


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Pronunciation: Gordon Bennett
Added on: 2009-12-04 Listened: 144 timesin: exclamations, slang, names, idioms, offensive
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Huevos Rancheros
30 May 2010
|Hot sauce
|1⁄2 Cup (8 tbs)
|6 (Corn Or Flour)
|Poached eggs/Fried eggs
|6 , hot
|1⁄2 Cup (8 tbs) (sliced avocado, sliced radishes, shredded jack or mild Cheddar cheese)
Prepare sauce and keep warm.
In an ungreased heavy frying pan over medium-high heat, place tortillas, one at a time, and heat until soft and hot (about 30 seconds on each side).
Put immediately into a covered ovenproof container or foil packet; keep in a 200° oven until all tortillas are heated.
For each serving, place 1 tortilla on a plate; top with a well-drained poached or fried egg and about 1/2 cup sauce.
Sprinkle with garnish of your choice.
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Huevos Rancheros Recipe


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Self Catering
Bendigo Ridge Holiday Home
1 Bendigo Ridge, Goodlands Road, Anerley, 4230, KwaZulu Natal
This 3 bedroom house sleeps 6 people. The home is fully furnished and linen and towels are provided. Just bring your own beach towels. The kitchen is fully equipped with a fridge/freezer, stove, microwave, kettle and washing ... read more
Price Range
Available on request
Self Catering
Banana Beach Holiday Resort
Melville Beach, 4230, Port Shepstone, South Coast, KwaZulu Natal
Located on the popular Hibiscus Coast, Banana Beach Holiday resort offers one a true fun filled relaxation. Located only 50m from the beach one is assured of an awesome sea views, and a truly relaxing and enjoyable ... read more
Self Catering
The Beach House Southport
10 Ocean Drive, Southport, South Coast, KwaZulu Natal
The Beach House has four tastefully decorated bedrooms, all with magnificent beach and sea views. Sleeping 8 adults and 4 children in trendy seaside luxury. The main bedroom features a king size bed and en suite bathroom with ... read more
Price Range
Available on request
Self Catering
2 Fourth Avenue, Umtentweni, 4235, South Coast, KwaZulu Natal
Ambleside is located on the South Coast of KwaZulu Natal and only an hour's drive from Durban, in the picturesque and tranquil village of Umtentweni. We are 80 metres from a deserted beach and you can wake up to the sound of the ... read more
Bed & Breakfast / Self Catering
Mdoni House Guest Lodge
10 Norwood Road, Umtentweni, South Coast, KwaZulu Natal
A warm welcome awaits you at Mdoni House Guest Lodge where we invite you to relax in the peaceful tranquillity of our house and garden. Mdoni House Guest Lodge provides ideal accommodation for the businessman, tourist or ... read more
Please Note
per unit / night
This rate is a guide only and is the lowest rate for 2 persons sharing a room/unit in the current season.
Prices vary depending on room/unit selection, occupancy and season; and are subject to change without notice.
Self Catering
3 Beachfront Road, Seapark, South Coast, KwaZulu Natal
This magnificent 13 sleeper cottage is right on the beach! DaBeach is a great place to simply relax and enjoy the beach right on your doorstep. The property is level with one step into the cottage and a split level inside - one ... read more
Guest House / Self Catering
Stephans Guest House
19 Old St. Faiths Road, Umtentweni, 4235, South Coast, KwaZulu Natal
Our seven luxury double rooms all enjoy a sea view with balcony or veranda from where one can gaze at the Indian ocean and listen to its whispering. Keep your eyes open as you might just be lucky and spot some whales and ... read more
Bed & Breakfast / Self Catering
Tweni Waterfront Guest Lodge
Lot 222, Casuarina Road, Sea Park, South Coast, KwaZulu Natal
Tweni Waterfront Guest Lodge lies on the North bank of the Umtentweni Lagoon, 3km North of Port Shepstone. We are easy to find and only 100m to the beach (great for kids as there are no roads to cross!). The Lodge has upmarket ... read more
Self Catering
Sandy Toes
2 Beach Front Road, Port Shepstone, 4241, South Coast, KwaZulu Natal
Sandy Toes is a typical 3 bedroom family holiday home just a stone throw from the beach. Walk into an open plan living area consisting of a lounge and dining room with a sun room opening to the wooden deck and entertainment pool ... read more
Self Catering
Barnacle Bill's Beach Cottage
8 Beachfront Road, Sea Park, South Coast, KwaZulu Natal
Barnacle Bill�s Beach Cottage, an original fishermen�s cottage, situated on the edge of the Admiralty Reserve, and about 25 paces to the beach sand, is the ideal family holiday home. There are loads of shops, restaurants and fun ... read more
Barnacle Bill's Beach Cottage is fully booked over the following dates � 27 March to 2 May 2015 � 8 May to 27 July 2015 � 3-13 September 2015 � 2-11 October 2015 � 22-26 October 2015 � 5 December 2015 to 5 January 2016
Self Catering
Pinnacles Seaside Unit
19 Ambleside Road, Umtentweni, 4235, South Coast, Kwazulu Natal
Just an hours drive from Durban in the Paradise of the Kingdom of KwaZulu Natal is Pinnacles Seaside Unit. Housed in an original South Coast beach cottage with high pitched ceilings and Oregon-pine floors; Pinnacles is an ... read more
Self Catering
Cosy Cabins
Southport, Port Shepstone, KwaZulu Natal
The romance of staying in a log cabin can be fulfilled when you stay at Cosy Cabins where two one bedroomed log cabins are nestled on the hillside in a pretty garden with sea views on the inland side of the main road in ... read more
Self Catering
2 Mzimayi, Mangrove Beach Estate
Bokmakierie Road, Port Shepstone, South Coast, KwaZulu Natal
Just 150m away from the unspoilt Banana Beach on a private path past a mangrove lined lagoon, this north facing, 2 bedroom ground floor unit, is uniquely placed on the quieter part of the Hibiscus Coast between Hibberdene and ... read more
2 Mzimayi, Mangrove Beach Estate is fully booked on the following dates � 20 - 22 May 2015 � 7 - 14 June 2015 � 3 - 18 July 2015 � 7 - 9 August 2015 � 24 - 26 September 2015 � 17 - 21 October 2015 � 16 December 2015 to 4 January 2016
Self Catering
Thandulula Luxury Safari Tents
14 Mhlangankulu Drive, Southport, Port Shepstone, KwaZulu Natal
The uniqueness of Thandulula lies in the fact that every luxury safari tent has its own bathroom, fully equipped kitchen, sleeping and relaxing area, and own deck area all under one roof. All units are equipped with two to three ... read more
Bed & Breakfast / Self Catering
32 Abelia Cresent, Sea Park, Port Shepstone, South Coast, KwaZulu Natal
Honeywood offers luxurious self catering accommodation on the South Coast of KwaZulu Natal, 6km north of Port Shepstone. This secluded spot provides an ideal get away in a quiet forest garden, only 700 meters from the beach. The ... read more
Why Book with SA-Venues.com
- Secure payments
- Accredited establishments
- Deal direct and save


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Mon-Fri: 7am-1am EST / Sat-Sun: 7am-11pm EST
ApplianceAmana Range
Level of DifficultyEasy
Time to do repairLess than 15 mins
Age of Appliance5 - 10 years
Screw driversSocket set
4 out of 4 people found this instruction helpful
The Job didn't take very long at all. I pulled the unit out and unplug it before I started the repair. I had to remove the back two access cover plates to get to the two wire leads that connect the broiler. I don't believe there was enough wire to be able to do it all from the front side. Next I disconnected the two wires that connected it while remembering what color goes to the correct side (just incase this does matter). After removing the wires I moved on to remove the element with a Philips screwdriver. The new part already had the hangers on it so I reused the old screws and installed the new element. Next I reconnected the wires in the back and re-installed the back panels. I plugged it up and it works as good as new now. This was definitely a lot cheaper to fix this myself than hire a repairman.
Help other customers find the most helpful instructions.
Were these instructions helpful?
Part Number: PS1745901
All brand logos are trademarks of their respective owners.
The PartSelect logo is a Registered Trademark of Atlantic Laundry Centres, Ltd.
Copyright © 1999-2015 , Eldis Group Partnership. All rights reserved.


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Deputies: Housekeeper cleans up, stealing more than $100,000 in jewelry
A Bonita Springs housekeeper cleaned up at the expense of her elderly clients, stealing more than $100,000 in jewelry and pawning it at shops in Lee and Collier counties, detectives say.
Authorities believe other victims have yet to come forward.
Linda Flemke, 37, of the 10000 block of Carolina Street, faces felony fraud, theft and exploitation charges after her arrest by Collier deputies on Wednesday.
Detectives with both counties' sheriff's offices and the Naples Police Department say Flemke pocketed rings, necklaces and sterling silverware from seven victims, all of whom were above the age of 75 and one of whom suffers from dementia.
Flemke maintained strong relationships with her clients, Collier detective Wade Williams said, and she sent Christmas cards and bought gifts for them during the holidays.
"She was their friend, as far as they were concerned, for years," he said.
Meanwhile, she peddled their jewelry at pawn shops and second-hand dealers in both counties, receiving little on the dollar value, reports say. In one case, she traded a $3,000 necklace for $640. When the distraught homeowner offered Flemke $500 to "find" the necklace, Flemke claimed she never had the piece.
Many of the items have been returned to victims, detective said. Unique markings, serial numbers and photographs provided by victims were all crucial in identifying and returning the jewelry.
Authorities wouldn't say what Flemke did with the money, although Williams said drugs may be involved in the case. He said the investigation remains ongoing to find additional victims and to determine whether anyone worked with Flemke.
Thursday, a jailed Flemke agreed to a one-day postponement of her first appearance before a judge, as Collier detectives expect they may add charges if more victims respond to the publicity of the case.
The current alleged victims — two in Bonita, one in Naples and four elsewhere in Collier — all allowed Flemke into their homes for weekly cleaning with her business, "Jackie's Gotcha Cleaning Service." Detectives said Flemke had a reputation as a good cleaner and was hired by many of her victims on word of mouth.
One of the alleged victims, a Bonita Springs woman born in 1927, was in failing health and losing normal functions, including the ability to hold a conversation, according to the report. Flemke ripped the woman off for at least $10,000 worth of necklaces, rings and bracelets, the report stated.
Williams received the first complaint about Flemke in May 2010. Evidence was insufficient to make an arrest at the time, he said, but he pursued the case.
"This is the type of situation where, if it's an ongoing thing like that, it's not going to stop until someone puts a stop to it," he said.
He coordinated with detectives in nearby agencies, Mike Detar of the Lee County Sheriff's Office and Joe Craig of the Naples Police. They placed holds on Flemke's pawned items and conducted surveillance.
When Flemke learned of the holds, she called Detar to arrange a meeting.
Wednesday, Detar, Williams and Craig met Flemke at the Naples Police station. Detectives showed her 60 pages of pawn records amounting to more than $100,000 in jewelry over the past two years. In one month alone, she made $5,400 in cash from stolen jewelry, Williams wrote in the report.
Flemke's statements were redacted from the arrest report, but detectives say she accepted responsibility for her actions.
For the combined seven cases, Flemke is charged with one count each of fraud to gain property over $50,000; theft of $50,000 or more from someone 65 years of age or older; and exploitation of the elderly for $100 or more.
The theft and fraud counts are both first-degree felonies, punishable by a maximum 30 years in prison. The exploitation charge is a third-degree felony, which carries a maximum five-year prison sentence.
Flemke told detectives during the meeting that had she been aware she was to be arrested, she would have "ran and never looked back," according to the report.
A judge is scheduled to set her bond on Friday.
The case offers a learning opportunity for others who allow strangers into their homes, authorities say. Among their advice is that owners document their jewelry or ensure it has a special marking or serial number; to know the full identity of anyone who enters their home; and to ask for ID to verify someone is who they claim to be.
Anyone believed to be a victim of Flemke, or who may have information about the case, is asked to call the Collier County Sheriff's Office at 239-252-9300 or Southwest Florida Crime Stoppers at 1-800-780-TIPS (8477).
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text:
Cheap PIE to Burlington flights
Popular Flights from St. Petersburg, Florida
Popular Flights from Burlington, Iowa
Top Burlington Flights to US Destinations
Top Burlington International Destinations
PIE to BRL Route Map
St. Petersburg to Burlington Flights, Stats and Airplanes
Route information for flights from St. Petersburg Clearwater Intl. to Southeast Iowa Regional.
1,010.06 miles


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A slew of big name stars — Leonardo DiCaprio, Nicole Kidman, Steve Martin, Robert Redford and Warren Beatty — and the smash TV show Downton Abbey were all victims of the notorious hacker Guccifer, RadarOnline.com has learned.
The Smoking Gun reports that Redford and Beatty's phone numbers were stolen by the hacker, as were Kidman and DiCaprio's e-mail addresses.
A script for Downton Abbey's season four finale was snatched six months prior to the episode's broadcast, according to the report.
PHOTOS: Stars Who Have Been Stalked
Guccifer's antics previously made headlines after the hacker infiltrated the personal accounts — including, in some cases, confidential financial statements, e-mails, and contact lists — of political figures such as Colin Powell, Bush and Rockefeller relatives, and members of President Barack Obama's administration. Other prominent personalities hacked include tell-all scribe Kitty Kelley, Star 80 beauty Mariel Hemingway and John Dean, a former Richard Nixon aide.
Most of the victims likely had no clue of the incidents, TSG reported.
In a bizarre twist, the hacker himself was the person to notify TSG of his latest celebrity conquests, telling the site he had a dream "in which a woman is stepping up to me saying that she is from Federal Bureau and I am busted" while he'd try "desperately to erase my files on my computer at my desk or on my smartphone which btw I don't have because I can't afford one."
Guccifer told the site, "i don't know what near future hold for me," and said he was sending many of his illegally-obtained findings to a reporter, "in case I disappear."


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Where do you put your Christmas tree?
If you put up a Christmas tree where do you put it in your house? If you have little kids do you have to put it up to keep them out of it?
I'm guessing we will have to put the tree up high again this year so that my 2 year old doesn't tear everything off of it lol. I can't wait until we can just put it up without worrying about it!
In our entryway of our house next to the stairway And no our kids don't mess with it our youngest is one
In the living room
In the living room. My biggest problem is keeping the cat out of it. LOL
Ours is in the living room. All the presents I have purchased so far are wrapped under there too.
We put it in the place where we can see it the most while home. That's our livingroom.
in our living room. I also have a 2 year old and I fully expect the bottom of the tree to be bare LOL. thats why we put the plastic ornaments towards the bottom.


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Dreamy waterfront vacation home with private pool
|No rental rates available - please contact the owner
|Pets allowed:
Bedrooms: 2
Bathrooms: 2
Sleeps: 4
Type: Home
Pets allowed: No
Internet: Yes
About the owner
Owner Profile
Availability Calendar
- 1 Queen Bed
- 2 Twin Beds
- Air Conditioning
- Lakefront
- Patio
- View (Lake)
- Beach Towels
- Lanai
- Porch
- View (Water)
- Full Kitchen
- Linens Provided
- Private Pool
- Waterfront
- Heating
- Outdoor Shower
- Screened Porch
- Wheelchair Accessible
- High Speed Internet
- Parking Included
- Alarm Clock
- DVD Player
- Refrigerator (Full)
- TV (Cable/Satellite)
- CD Player
- Dishwasher
- Stereo
- Telephone
- Ceiling Fan
- Microwave
- Stove
- Toaster
- Charcoal Grill
- Oven
- TV (Antenna)
- Washer/Dryer
- Coffee Maker
- Radio
- Bicycling
- Shopping Area
(<1 mile)
- Deep Sea Fishing
(2 miles)
- Water Skiing
(3 miles)
- Fishing
- Boating
(1 mile)
- Hiking
(2 miles)
- Windsurfing
(3 miles)
- Lake
- Bowling
(1 mile)
- Kayaking
(2 miles)
- Winery
(10 miles)
- Pool
- Golf
(1 mile)
- Beach
(3 miles)
- Aquarium
(20 miles)
- Basketball Court
(<1 mile)
- Gym/Fitness Center
(1 mile)
- Ocean
(3 miles)
- Zoo
(20 miles)
- Grocery Store
(<1 mile)
- Miniature Golf
(1 mile)
- Sailing
(3 miles)
- Amusement Park
(25 miles)
- Park
(<1 mile)
- Movie Theater
(1 mile)
- Scuba Diving
(3 miles)
- Theme Park
(25 miles)
- Playground
(<1 mile)
- Canoeing
(2 miles)
- Snorkeling
(3 miles)
- Water Park
(25 miles)
- Restaurant
(<1 mile)
- Casino
(2 miles)
- Tennis
(3 miles)
Reviews (10)
Reviews for this vacation home rental in Port Richey, Florida
James Basile
Debbie Hughes-Siegert
Buffalo, ny
May 7, 2013
The property owner is very attentive. Very easy to work with and if you have a problem she is right there to help make your vacation perfect.
Ted Boisvert
Ted and Theresa
May 7, 2012
The home worked out wonderful for us.Close to my son and grandchildren.It was great!! The owner was very nice. Shopping was no problem. The house felt cozy. Cooking morning beackfast was liking being at home .Thanks
Marilyn Rogers
Hamilton, Ontario, Canada
Spring Training for the Blue Jays
April 18, 2012
Our stay at this rental for March 2012 was very enjoyable. The advertisement for this home is right on the money! We found the house to be very comfortable and cozy. Everything was at your fingertips both in the house and out in the community. Loved my shopping trips to the department store called Beall's. Our main reason to visit the area was to take in all the spring training games for the Blue Jays. A bit of a drive tp the games but well worth it. The weather was excellent for the entire month. The locals said it was an unusually hot month this year. I would like to thank the caretaker Angela and her husband along with the owner Doris. They were just awesome. The only negative thing was the cable service to the home gave you access to HD channels however, the TV's were not HD ready and therefore watching TV was a bit annoying. Would I recommend this rental? YES! I would not hesitate to return to this rental again. Frank & Marilyn Rogers
Arlen Carlson
Lake of the Ozarks, Missouri USA
Great place to spend February!
March 7, 2012
This was our first trip to spend a month in Florida and was very pleased with the accomodations. The pool was just like the picture. We tried swimming a couple times but the water was just a bit cold. We were concerned about the safety in the neighborhood since we hadn't been in the area before but found after a few days that the neighborhood was safe. We walked several times around the area and found the neighbors were nice and friendly too. Would we recommend it to other travelers. YES. Oh, we had our 5# dog Allie with us and she enjoyed the secure fenced yard and liked to watch the ducks and squirrels.
Diane Hodge Hess
Chicago, IL
Home Away from Home!
April 3, 2011
It wasn't easy to leave this lovely home with such a beautiful backyard full of lush trees, pond, ducks and turtles. The yard is very quiet and private. House was clean and well decorated. Everything you need is there. The owner of the home is very pleasant and makes sure all is well. If, for any reason, you need help with anything, the caretaker responds immediately. We would return to his house in a second, but next year we are going to vacation near friends elsewhere in Florida.
Susan Abbott Effler
Maryville, TN
Hoping to Return Soon!
February 2, 2011
My husband and I stayed in this lovely home recently and we loved it there. It was very neat, clean and comfortable, and even when the weather wasn't great, it was cheerful because of the view of the pool, lanai and pond. It is near grocery stores, shopping, and of course the beach is only a few miles away. (We loved the restaurant on Hudson Beach.) Our vacation there was a very pleasant experience, and we're already hoping to return. Also, the owner and caretaker are both exceptionally nice people. Thank you, Bruce and Susan Effler
Rockville Centre, NY
August 1, 2010
What a wonderful experience renting this little piece of paradise. Clean, comfortable, affordable luxury. Great ammenities, swimming in the morning and watching the wildlife while having your morning tea. What is better than that? Dealing with the owner was a pleasure and we enjoyed our relaxing stay so much we can't wait to go back again soon.
Douglas Cates
Childersburg, AL
Relax, Chill, unwind.
June 25, 2010
I need a place just to relax and unwind for a while and this was just the place. It's close enough to civilization for the shopping and dining conveniences and sites but out away from all the hustle and bustle. The house was very cozy and relaxing having everything needed. Mainly though I loved that pool and the lanai. It was cool to watch the turtles and ducks from the pond also. The property manager was also very helpful, so a big kudos for her. Loved this place. Only bad thing was I had to leave.
New York, NY USA
Dreamy. . .Definitly!
March 13, 2010
My husband and I spent a week here in February with our teenage daughter. We loved the waterfront view and it was a nice change from our usual fast city living and there were alot of activities for us to do as a family. My daughter especially loved the amusement park, and my husband and I got some time alone to go wine tasting. When we wanted to relax the house really was the perfect spot to hang out and lounge by the pool in private. Overall, I definitely recommend this vacation home for your next getaway.
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Let's Talk Health
Let's Talk Health is a production of the University of Memphis' Department of Communication and the Loewenberg School of Nursing to empower you to communicate and make healthy choices. See more information at http://www.memphis.edu/letstalkhealth.
Last Modified: 04/02/2013
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Check Ask TOM for a solution:
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text:
ACCA Publishes R-22 ComforTool
March 5, 2012
ARLINGTON, Va. — The Air Conditioning Contractors of America (ACCA) recently published its latest ComforTool. The latest series installment, "Why is the Price of R-22 Refrigerant So High?" explains why the price of the R-22 refrigerant recently increased and what may happen in the future.
"The recent spike in the price of R-22 has caused a lot of frustration and confusion among contractors and their customers," said Paul T. Stalknecht, ACCA president and CEO. "This ComforTool serves as an explanation of what is going on in the market and how the price of the refrigerant is out of the control of contractors. We hope this will help our members deal with some of the pushback they are getting from their customers in response to the price increases."
ACCA members can download the R-22 ComforTool, and any previous series inclusions, for free at www.acca.org/comfortools.
Publication date: 3/5/2012


text:
Recent Comments
- 7 months ago it would be so cool to win
- 8 months ago Imore is awesome !!! Thanks for giving us another chance
- 8 months ago I tried the family sharing... and like others so far we are not able to share iTunes match. If we have paid for it I...
- 8 months ago I like Imore like a like the new iPhone Sent from the iMore App
- 9 months ago Looking forward the Health App & NFC
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- 10 months ago Imore have the coolest giveaways
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- 12 months ago Will this happen with Beats ?
- 12 months ago Well Apple is known for taking something and improving on it.
- 1 year ago Imore gives insight and giveaway apple products. Apple make great products and technology
- 1 year ago I like apple for the simplicity
- 1 year ago The reason I like apple is the marriage between simplicity
- 1 year ago What isn't there to not to love about Apple. Apple perfects everything then innovate something that no one ever thinks of...
- 1 year ago I would prefer Apple TV since I have an Iphone. So ill be in the Apple ecosystem
- Member for
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If you'd like to
be updated on meeting changes, upcoming events and other
AA-related topics, click here.
Your group can become famous! Make a video for the 2015 Anniversary
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By Area
If you
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This site created and maintained for alcoholics everywhere.
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text:
I have to build a dynamic form in my activity depending on the data retrieved via HTTP that is popullated from XML.
This could be one or more
RadioGroups each with exactly three
RadioButtons. After RadioGroups I need to place two
EditText and one
CheckBox control with submit button afterwards.
I have prepared a
LinearLayout with vertical orientation and unique ID to be addressed from code and I expect that I can create a form control within a Java code without defining in android XML layout and adding to this
I was googling for a few hours but could not find any example how to do this.
Could anyone please provide some example how to create e.g. one
RadioGruop with 1-2
RadioButtons and add it to the
LinearLayout (that is prepared in XML layout)?
Many thanks for any advice!!!


text:
Download Music VideosUse YouTube Downloader for much, much more than downloading YouTube videos.
in TONE a rue MORE on – Recent 75…
- Gordon Lightfoot Live at the BBC
- Ultimate Muscle Roller Legend
- Fukkireta Eagle Dance
- Knelt Rote – Usurpation
- Grateful Dead – Hell in a Bucket
- Carpenter Brut – Escape from Midwich Valley
- Poison Idea – Bog
- Peaking Lights – Breakdown
- Richard Dawson – Poor Old Horse
- Ian Andrews – HiFi Facts
- Steve Reich – Come Out
- Reece Shearsmith – Put on a Happy Face
- Brian Eno – Dead Finks Don't Talk
- Clark – Shuttle Track
- Vietnam Gong Ensemble
- Plaid – T.E.T.H.E.R.
- Nathan Shields – Pancake Fluit
- Anonymous – Turkey in the Straw
- Karsten Pflum – Impulse 11
- Sosaku Kalimba Kobo – Jesus, Joy of Man's Desiring
- Murcof – Rostro
- Giorgio Mainerio – Caro Ortolano
- Dux Content – Lifestyle
- GuiGui Zheng – Piano Performance
- Three Instruments
- Rick James: You and I
- Moritz Simon Geist – MR808
- Jim Croce – Operator
- Cotton Eye Joe – The Country Sisters
- Corvus Corax – Saltarello
- Peaches – AAXXX
- Rachid Taha, Mick Jones, Brian Eno – Rock the Casbah
- Sachal Studios – Take Five
- Bonnie Poe and Bela Lugosi – Betty Boop Meets Dracula
- Chairman Kim Makes My Panties Wet
- Kate Bush – Sat in Your Lap
- QT – Hey QT
- Pete Shelley – Telephone Operator
- Leslie Lemke – Concert for Mom
- Liquid Sky (1982)
- Apache – The Shadows
- Dyko – Autobahn
- 3 Guys and a Tractor
- Laibach – Warm Leatherette
- Blade Runner Geisha Eating Candy
- Adi Ulmansky – Was It You?
- Hexstatic – Guerilla Gig
- Frank Perri – Bach Cantata BWV 147, Jesu Joy of Man's Desiring
- Mark Mothersbaugh – Thinking Cap
- FKA Twigs – How's That
Category Archives: podcasts
The Old Silverback Hour – Pedicab Stridency
One full hour of variety in the popular music genre. Originally broadcast over the experimental HEER-ZUM radio network on or about the week of April 1st 1927. Fans of old time radio will enjoy this offering. Restored from the original … Continue reading
Posted in podcasts, radio Leave a comment
Underworld Amusements – Mencken/Scopes
"In the summer of 2010 I recorded and released a series of podcasts dedicated to the infamous Scopes Trial of Dayton, Tenn. The idea occurred to me near the end of 2009, and I was just able to get everything … Continue reading
Posted in podcasts Tagged underworld amusements 2 Comments
H. L. Mencken – Homo Neanderthalensis
"Welcome to the first installation of an ongoing series of reports on the Scopes Trial in Dayton Tennesee in 1925, exactly 85 years ago! The trial was the first in the US to be broadcast on the radio. Those recordings … Continue reading
Posted in podcasts Tagged underworld amusements Leave a comment
American Knucklehead #19 Now Available!
AK-019 – From Bubble to Bubba Joe pays a holiday visit to the heartland and reports on what's on the minds of American Knuckleheads. Bowl games, screamin' airplane babies and a touching family moment make this a very special episode … Continue reading
Posted in podcasts Tagged american knucklehead Leave a comment
American Knucklehead #18 Now Available!
AK-018 – Iraq and Roll Over The spittle flies as Joe gets really worked up about the end of the war in Iraq. With worse-than-usual profanity, he asks the important questions about the war that no one in the media … Continue reading
Posted in podcasts Tagged american knucklehead 1 Comment


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Greater Saskatoon Catholic School Division
From Wikipedia, the free encyclopedia
(Redirected from Saskatoon Catholic School Division)
|Greater Saskatoon Catholic School Division (St. Pauls R.C.S.S.D No. 20)
|Type and location
|"Putting faith in education!"
|Students and staff
|Other information
|Board Chair
|Jim Carriere
|Teachers' union
|Saskatchewan Teachers' Federation
|Greater Saskatoon Catholic Schools
Greater Saskatoon Catholic School Division is Saskatchewan's largest Catholic school division. The Greater Saskatoon Catholic School Division has approximately 15,000 students in 44 schools located in Saskatoon and surrounding rural districts. St. Pauls R.C.S.S.D No. 20 belongs to Department of Saskatchewan Learning Division 4 along with Englefeld Protestant Separate S.D. No. 132, Horizon School Division No. 205, Prairie Spirit School Division No. 206, Saskatoon School Division No. 13, Sun West School Division No. 207 and Division scolaire francophone 310.[1]
Elementary schools[edit]
- Bishop Filevich Ukrainian Bilingual School
- Bishop Klein School
- Bishop Pocock School
- Bishop Roborecki School
- Cardinal Leger School (French Immersion)
- Father Robinson School
- Father Vachon School
- Georges Vanier School
- Holy Family School
- Mother Teresa School
- Pope John Paul II (St. Thomas) School
- St. Angela School
- St. Anne School
- St. Augustine School
- St. Bernard School
- St. Dominic School
- St. Edward School
- St. Frances School
- St. George School
- St. Gerard School (French Immersion)
- St. Maria Goretti Community School
- St. John School
- St. Luke School
- St. Marguerite School
- St. Mark School
- St. Mary Community School
- St. Matthew School (French Immersion)
- St. Michael School
- St. Paul School (French Immersion)
- St. Peter School
- St. Philip School
- St. Volodymyr School
- Sister O'Brien School (French Immersion)
- Saskatoon French School (French Immersion) (Associate School)
Rural Schools[edit]
Special programs[edit]
- Cyber School
- Farm School Program (Bishop Murray)
- START Program (St. Frances)
- Deaf and Hard of Hearing Program (St. Frances)
- Living Our Faith Together (LOFT) Program (E.D. Feehan Catholic Highschool)
- Opening Doors Program
- White Buffalo Youth Lodge
High schools[edit]
- Bethlehem High School
- Bishop James Mahoney High School
- Bishop Murray High School
- E.D. Feehan Catholic High School
- Holy Cross High School
- Oskayak High School (formerly known as Joe Duquette High School)
- St. Joseph High School
- ^ Section 7: Saskatchewan School Divisions, retrieved 2008-12-21
External links[edit]
|This Saskatchewan school-related article is a stub. You can help Wikipedia by expanding it.


text:
Thoughts from the EPS Windows Server Performance Team
Useful Microsoft Blogs
Platforms Blogs
We often get questions on configuring Terminal Server Authentication. The questions have less to do with configuring a simple logon scenario than they do with preventing attacks, in particular "Man in the Middle" attacks – especially when the Terminal Servers may be publicly accessible. For those of you who are unfamiliar with the "Man in the Middle" scenario, this describes a situation in which an attacker intercepts the communication between two parties, and impersonates each one to the other. There have been several improvements in Terminal Server security that can protect against attacks.
Our fellow bloggers on the Terminal Services team published post on Configuring Terminal Servers for Server Authentication to Prevent "Man in the Middle" Attacks. The post covers Network Level Authentication (NLA) and using SSL / TLS (among others).
Until next time …
- CC Hameed


text:
Man Utd keeper Van der Sar: Ferguson management absolutely unparalleled
Edwin van der Sar admits Manchester United boss Sir Alex Ferguson convinced him to sign his new 12-month deal last week.
The Dutch keeper, 39, said if he only had Premier League games to look forward to, he would have called it a day.
"There is not another bloke in the world like Sir Alex. I really think he is a unique coach, unparalleled.
"The way he has us playing is everything I think football should be be: utter concentration, reaching peak moments at the right stages.
"I only have to think about the AC Milan game. What a joy it was. I have to be honest, if I only had Bolton away to look forward to, I wouldn't carry on playing in England."


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meteorological stations Companies in Lithuania
Opsis AB
based in Furulund, SWEDEN
Opsis AB is the leading supplier of open-path monitoring systems for air quality monitoring, continuous emissions monitoring (CEM) and process control. Opsis offers total monitoring solutions and the product line includes both monitoring hardware and data handling software. The DOAS technology, developed by Opsis, has received international approvals and provides ...
Mierij Meteo Nederland
based in De Bilt, NETHERLANDS
Mierij Meteo systems was founded in 1982 and delivers solutions for projects where meteorological information is essential. Mierij Meteo is an innovating company that keeps innovating their meteorological sensors and systems with the goal to improve the quality of your measurements, to improve your saftey, to reduce your cost of ownership, to improve reliability and to ...
RainWise Inc.
based in Trenton, MAINE (USA)
RainWise Inc. manufactures professional weather stations and other meteorological equipment for consumer and industrial applications. We feature solar powered wireless weather stations, data loggers, rain gauges, advanced cellular telemetry, PV array environment monitors, wind measurement loggers, anemometers, barometers, thermometers and a variety of other weather ...
World Meteorological Organization (WMO)
based in Geneva 2, SWITZERLAND
The World Meteorological Organization (WMO) is a specialized agency of the United Nations. It is the UN system`s authoritative voice on the state and behaviour of the Earth`s atmosphere, its interaction with the oceans, the climate it produces and the resulting distribution of water resources.
Meteorological Solutions Inc. (MSI)
based in Salt Lake City, UTAH (USA)
Meteorological Solutions Inc. (MSI) is an air quality and meteorological consulting company with a strong emphasis on near-field dispersion modeling, far-field dispersion modeling, and air permitting. We can provide complete meteorological and air quality monitoring services including initial site selection and permitting, monitoring systems integration and installation, ...
Skandinaviska Meteorologi-Och Miljoinstrument AB
based in Stockholm, SWEDEN
Skandinaviska Meteorologi-Och Miljoinstrument AB, is a Swedish company. We develop, manufacture and market products and services for environmental, meteorological and water measurement to allow: Observing, monitoring, recording and reporting weather, water resources, climate and the related natural environment; Providing beneficial weather, water, climate and related ...
Delta-T Devices Ltd
based in Cambridge, UNITED KINGDOM
Delta-T offers a wide range of data loggers and sensors able to measure and record hydrological, meteorological and other environmental parameters. Our products provide direct measurements of the forces and effects that renewable energy and other environmental technologies attempt to harness, control or monitor.
Umwelttechnik MCZ GmbH
based in Bad Nauheim, GERMANY
MCZ has more than 25 years of experience in the construction and manufacture of apparatuses and systems in the area of gas analysis and related fields. MCZ develops and manufacturers devices and systems for end customers as well as OEM systems. Gas Collectors, Calibration Systems for Gas Analyzers, Inspection Stations and Test Benches, Zero and Process Gas treatmentg, Gas ...
Climatronics Corporation
based in Bohemia, NEW YORK (USA)
Climatronics Corporation is a leading manufacturer of weather sensors and instruments and large integrated environmental monitoring systems in the United States. For over 40 years, we have been dedicated to producing the highest quality, state-of-the-art equipment, and through continued excellence have established ourselves as one of the leading companies in this field.
Felix Technology Inc.
based in Concord, ONTARIO (CANADA)
Felix Technology is an integrator and provider of sensors and systems for measuring and monitoring meteorological, hydrological and environmental parameters. Our main focus is on developing quality instruments and providing engineering solutions to frequently encountered environmental problems. Our highly skilled technical and sales personnel make sure that the customers ...


text:
Conan O'Brien Farewell Speech
What a class act. I'll admit it - it made me a little misty eyed. I wish nothing but success to this great entertainer.
This post was created by a user and has not been vetted or endorsed by BuzzFeed's editorial staff. BuzzFeed Community is a place where anyone can post awesome lists and creations. Learn more or post your buzz!
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text:
Huskies have trouble adapting to our climate. But can this one? Kartikeya Singhee finds out
Husqvarna is a name most Indian bikers would only have heard of vaguely. Many upheavals in the Swedish brand's rich history now has their bikes built in Varese, Italy. 'Huskies' as this marquee's products are popularly known are generally focused, top class off-road motorcycles. With the Nuda 900R almost here via Navnit Motors, we sling a leg over the Nuda for a few hours to check what it's about.
Although it is outlandish in its entirety, the details on the Nuda are incredibly stylish. The attractive instrument cluster houses an analogue rev-counter in the centre with telltale lights stacked on the left, while the LCD display on the right shows the speed prominently. The slashed exhaust with its carbon-fibre end-plate, clamp and shield, the cast-alloy side stand, the black anodised handlebar, the vented sprocket cover, motocross-cum-street footpegs, and the slinky grab handles for the pillion are stunning details on a masterful blueprint.
Overall, the Husqvarna makes its supermoto intentions quite clear. It is a tall motorcycle with an upright stance and offers a narrow and flat seat running from the tank to the tail section. The exposed trellis frame, big motor and massive rubber sit denuded underneath.
The 798cc liquid-cooled parallel-twin engine has been bored and stroked to stretch the displacement to 898cc. Bigger-diameter valves have been used to cope with the added displacement. Finally, instead of a zero-degree crank as on the GS, the Nuda uses a 315-degree crankshaft to deliver the character and power befitting a Husqvarna. To mark the motor out as a Husky engine, the cam cover is painted red.
The Husky comes well equipped too. It gets top-flight radially-mounted, four-pot mono-bloc calipers for the twin 320mm discs, with 48mm Sachs upside-down forks for springing duties. At the rear, there is a completely adjustable Ohlins unit and a 265mm disc with two-piston calipers. Shod in Metzeler rubber, the Nuda 900R is brimming with confidence.
Once you've clambered onto the saddle and thumbed the starter, you are greeted by a fantastic exhaust note. Bass, volume and the howl of trapped power waiting to break free all burst through the slashed exhaust in just the right mix. Sure, 103bhp might not sound like much for a near-litre-class bike, but the Nuda is high on adrenaline. Throttle response is, quite simply, frenzied.
The mildest twist of the right wrist sends the Nuda 900R charging forward. Hang on harder as you near the 4000rpm mark. There's always a sense of confidence that makes this motorcycle thrilling rather than scary.
The Nuda's ECU has an alternate 'MAPII' engine map that softens power delivery significantly. Suddenly, stop-go traffic is no longer a bother and even ham-fisted inputs won't cause the Nuda to misbehave.
Both versions of the Nuda use double discs at the front. However, the bite from the 900R's mono-bloc set-up is ferocious enough to rival the engine's performance.
The steel-braided hoses provide a crisp feel at the lever and it takes only a light tap to check city speeds. A harder pull is only for shedding serious speed. The front 120/70 R17 Metzeler felt confident and rock-solid too. However, for such an edgy motorcycle, an ABS system would have been of great help in the Indian environment.
The Nuda's design, components and character come together and tempt you to give the supermoto style of riding a shot. Given adequate time and space, the Nuda will have you sliding into corners spinning the rear wheel, and popping the front wheel on the way out. It's a motorcycle that will urge you to man up and hone your riding skills.
Surprisingly, apart from the high seat, the Nuda is a bike that can be used regularly. The slim seat is a bit firm, but the pliant ride keeps things comfortable. Despite Mumbai's roads throwing their worst at the Husky, the long-stroke front suspension and well-damped rear allowed only a few sharp edges to filter through to the rider. The generous lock-to-lock steering movement also makes it quite manoeuvrable. Husqvarna claims that the 13-litre fuel tank is more than sufficient to cover 260km between refills. However, the high-compression motor does require a premium fuel diet to keep it running without any hiccups.
If you are willing to brave the tall saddle, the Nuda 900R (built under the tutelage of German automotive powerhouse, BMW Motorrad) is among the more exciting street-worthy introductions to the Husqvarna brand. However, its Rs. 18 lakh (ex-showroom, estimated) price will make it a high that very few will be willing to stretch for.
Keywords: Huskies, Nuda 900R, Navnit Motors, Husqvarna, bike reviews, automobile reviews