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Transformation toward value-based healthcare is reshaping the delivery of care, patient expectations, and payment structures.
Improve your revenue cycle performance through standard metrics, peer comparison, and successful practices.
If you're already participating in or thinking about a new payment model, you've probably seen that the pundits insist you must have a full IT infrastructure in place before you push the button on these initiatives. Whether it's a Medicare accountable care organization (ACO), bundled payment, an ACO-like arrangement for a payer's Medicare Advantage or commercial business, or even your own self-funded employee health plan, following this advice could mean IT investment requirements of $2.0 to $20.0 million.
It's enough to make you reconsider participation. Fortunately, there are simpler and less expensive ways to address immediate IT needs for these programs. You don't have to take on implementation of a major IT infrastructure solution to identify opportunities for improvement, manage value-based contracts, and monitor financial performance. The early rounds of the new payment models offer upside-only options (e.g., Track 1 of the Medicare Shared Savings Program) that significantly mitigate risk. These options give you time to ramp up your infrastructure incrementally, investing less now, while preparing for the more significant financial exposure that will inevitably come with the next round of payment deals.
Your most important first step is to master the data. Without clean, reliable, and integrated data, the best IT solution out there is worthless. Once your "data house" is in order, you can prepare for that perfect population health management solution, matching the investment to your degree of financial exposure. By that time, the IT solution market will have shaken out, pricing will stabilize, and unfulfilled promises should be a thing of the past.
Medicare, the health plans, and third-party administrators (TPAs) provide ACOs and participants in the Bundled Payments for Care Improvement Initiative (BPCII) with claims data. This data can be scrubbed and integrated with cost, quality, and other data from legacy systems to produce a robust database. Coupled with relatively affordable but still powerful reporting and analytic tools, this type of solution is all you need to monitor and manage financial performance. It enables you to understand how you are doing along the way, month to month, quarter to quarter, long before reconciliation with Medicare or the payer.
This approach also will help you answer important questions to inform and help you prioritize improvement initiatives—a necessary capability during a three- to five-year ramp-up to that eventual "financial risk" tipping point. You'll be able to answer questions like:
You will have what you need to really understand the financial implications at the patient, physician, practice, hospital, or regional level. A robust population health solution can be the goal once the concept is proven, but in the meantime, you can keep your finger on the pulse of all of your value-based payments without losing your shirt.
So the IT issue should not scare you off; strategic and physician engagement considerations probably carry more weight. Invest wisely, step by step.
Dan Grauman is CEO, DGA Partners, Bala Cynwyd, Pa.
Idette Elizondo is a manager, DGA Partners, Bala Cynwyd, Pa.
Publication Date: Thursday, January 23, 2014
Gordon Mountford, executive vice president, Huron Healthcare, discusses business imperatives for undertaking transformative change.
Gordon Mountford, executive vice president, Huron Healthcare, discusses business imperatives for undertaking transformative change.
Tom O'Neill, CEO of Xtend Healthcare Advanced Revenue Solutions, discusses key areas where organizations risk revenue leakage and ways they can use outsourcing to better protect cash flow and support accurate payment.
Tom O'Neill, CEO of Xtend Healthcare Advanced Revenue Solutions, discusses key areas where organizations risk revenue leakage and ways they can use outsourcing to better protect cash flow and support accurate payment.
Victoria Terekhova, senior strategist for Enterprise Healthcare at KeyBank, discusses key challenges when developing long-term strategy in a rapidly changing industry, and the role the right banking partner can play in helping healthcare providers navigate the opportunities before them.
Victoria Terekhova, senior strategist for Enterprise Healthcare at KeyBank, discusses key challenges when developing long-term strategy in a rapidly changing industry, and the role the right banking partner can play in helping healthcare providers navigate the opportunities before them.
Tom Myers, chief strategy officer, The SSI Group, discusses the shifting payment environment and how it affects providers' patient access and claims management processes.
Jeff Chester, senior vice president and chief revenue officer at Availity, shares his thoughts on "Revenue Cycle 2.0" and how to best meet its challenges.
Mitch Morris, vice chair and global leader, healthcare, Deloitte, and Michael O'Rourke, senior vice president and chief information officer, Catholic Health Initiatives (CHI), share perspectives on the need for transformational IT in health care today.
Brian Kueppers, founder and CEO, Apex, discusses the importance of a robust patient payment strategy in boosting organization revenue and enhancing patient satisfaction.
Brian Grazzini, CFO, HealthPort, describes the importance of efficient and compliant information exchange and audit management in helping HIM staff spend less time on paperwork and more on mission-critical projects.
Cindy Matthews, executive vice president, Community Hospital Corporation, discusses how rural and community hospitals can use collaborative partnering to position for success through tough market conditions.
Rick Heise, senior vice president, revenue cycle, at Cerner Corporation, discusses the importance of integrating clinical and financial data to excel in health care's changing payment environment.
Russ Graney, founder and CEO for Aidin, and John Laursen, head of business development for Aidin, share insights on how to improve care transitions between acute and post-acute care settings and incentivize high-quality patient outcomes.
Scott Elston, strategic accounts manager, GE Healthcare Services, describes how substantial cost reduction in health care requires rethinking business strategy and asset use.
Robert Williams, MD, director, Deloitte Consulting LLP, and Arielle Freiberger, product strategist, ConvergeHEALTH by Deloitte, explain how sophisticated retrospective, real-time, and predictive data analytics can inform decision making to reduce costs and improve care.
©2015 Copyright Healthcare Financial Management Association
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The tragic death of four workers falling on a construction site on Christmas Eve 2009 in Toronto, Ontario garnered nationwide media attention and quickly became known as one of the highest profile workplace accidents in Ontario. The accident spurred a historic, comprehensive review of Ontario's occupational health and safety system and led to amendments to Ontario's Occupational Health and Safety Act (OHSA). It also resulted in both regulatory and criminal charges being filed against the parties involved in the construction project.
On June 15, 2012, Metron Construction entered a guilty plea to one charge of criminal negligence causing death under the Criminal Code. Its President also pleaded guilty to four charges under the OHSA. The President has not as yet been sentenced. A joint submission has been placed before the court for a fine of $22,500 per charge, for a total of $90,000. Similarly, Metron has not yet been sentenced on its guilty plea to the criminal negligence charge. The Crown has sought a penalty of $1 million dollars. The defence has not yet completed their submissions on sentencing.
This case is the first corporate guilty plea in Ontario under the Criminal Code as amended by Bill C-45 in 2004. If imposed, a corporate sentence of one million dollars will represent the highest penalty for criminal negligence causing death for a workplace accident in Canadian history. The only other prior corporate criminal negligence conviction in such a matter, on a guilty plea in 2008, was Transpave, resulting in a fine of $100,000.00 in Quebec. The proposed fine against Metron's President will, if imposed, set a new high water mark for a sentence against any individual, let alone a director and officer under an OHS statute in Canada.
For further information please do not hesitate to contact Cheryl A. Edwards firstname.lastname@example.com, Jeremy Warning email@example.com, Shane Todd email@example.com, or Julie-Anne Cardinal email@example.com.
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Staff Reporter
Pictures from different countries to be shown to students
CHENNAI: Feature films that are made often make children forget that they are children and push them into the world of adulthood before they are prepared for it, Fr. Stanislaus Swamikannu, chairman of the Don Bosco institutions, said here on Tuesday.
He was speaking at the inauguration of an International Children's Film Festival organised by the Don Bosco Institute of Communication Arts (DBICA).
"There is exaggerated violence and sometimes, there are good social messages in films…but it is human nature to like whatever is interesting, glamorous and sleazy," he said.
Commending the DBICA for organising an exclusive festival of films for children, he said the list of films being screened in the festival were child-centric, focussing on fun, friendship and genuine affection.
Cricketer Dinesh Karthik, alumnus of the school, recalled his student days there that were filled with fun.
Actor Devayani Raajakumaran, guest of honour, told children to "study hard, have lot of fun and enjoy. "It is sad that not many films for the children are made in our film industry. I hope more children's films are made," she said.
Film director Alagappan, whose children's film 'Vannathupoochi' will hit the cinemas soon, said children were often burdened with academic pressure and lose out on playtime and fun.
Films from different countries, focussing on children, were to be screened to the audience that largely comprised middle school students from different city schools. Managing director of Mathi group of Industries M.S. Vadivel and principal of the school Fr. Jayaprakash Reddy were among others present.


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Thaw Out in Snowmass
The first ever Spring Weekend Meltdown in Snowmass is a chance to ease the transition from snowboards to pools and flip-flops. The three-day event combines the Snowmass Chili and Brew Fest with acrobats, DJs, dancers, models and an end-of-the-weekend Recovery Pool Party. "The Chili and Brew Fest has been going on for years at Snowmass," promoter Kevin Larson says. "We just added the After Dark Party and Pool Party to keep the weekend going."
Entertainment includes George Clinton, the Wailers and Brett Dennen. The Seasonal Brew Sampling and People's Choice Chili Tasting on Friday and Saturday offer a chance to warm your tastebuds and cool your tongue. Starting at 10 p.m. on Saturday, the After Dark Hotel Event includes performances by MTV recording artist Allie Pierre, DJ Brian Howe and the National Performers Alliance made up of acrobats, dancers and models. "It could be anything, from characters doing back-flips to people doing trapeze," Larson says.
The Meltdown lasts from 4:30 p.m. today until 2 p.m. Sunday in Snowmass Village and at the five-star Viceroy Hotel, 130 Wood Road. Tickets are $99. For more information, call 720-936-2999 or go to www.kevinlarsonpresents.com.
June 4-6, 2010
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What's happening in town? From underground club nights to the biggest outdoor festivals, our top picks for the week's best events will always keep you in on the action.
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- SIA Snow Show
Upcoming Events
Stumble Monkey (Free Show)Fri., May 15, 8 p.m.
Anaal NathrakhFri., May 15, 7 p.m.
Fit for an Autopsy and AbortedMon., May 18, 7 p.m.
Colorado Ballet AcademySun., May 17, 6 p.m.
- Tickets
- Screw Your Resolution Party


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from The Great Debate:
Why arming U.S. allies can be like sending weapons straight to the enemy
from The Great Debate:
Vast majority of those who fought Iraq, Afghan wars won't get pensions
from The Great Debate:
Don't believe the U.S. military when it says it doesn't keep body counts
from The Great Debate:
Stop the Pentagon program that militarizes U.S. police forces
The article originally ran last October. It has been updated by the authors.
There is a growing bipartisan public outrage about the local police force's fiercely militarized response to protestors in Ferguson, Missouri.
from The Great Debate:
Violence or vaccines: Which path for U.S. in Africa?
Africa is the new frontier for the U.S. Defense Department. The Pentagon has applied counterterrorism tactics throughout the Middle East and, to a lesser extent, Central and South Asia. Now it is monitoring the African continent for counterterrorism initiatives. It staged more than 546 military exercises on the continent last year, a 217 percent increase since 2008, and is now involved in nearly 50 African countries.
from The Great Debate:
Pentagon's big budget F-35 fighter 'can't turn, can't climb, can't run'
Americans should be worried.
The U.S. military has grounded all its new F-35 Joint Strike Fighters following an incident on June 23, when one of the high-tech warplanes caught fire on the runway of a Florida air base. The no-fly order -- which affects at least 50 F-35s at training and test bases in Florida, Arizona, California and Maryland -- began on the evening of July 3 and continued through July 11.
from The Great Debate:
Watch out, that freighter may actually be a warship
U.S. military operations now increasingly begin and end at sea -- aboard a growing fleet of vessels that the Pentagon has specifically outfitted as floating command facilities, barracks and launch pads.
from Stories I'd like to see:
America's biggest boondoggle and 'REAL' voter ID
1. The book on America's biggest boondoggle:
Last week, the Government Accountability Office issued the latest report on the F-35 Joint Strike Fighter, warning that "delays in testing of the jet's software may hinder delivery of the warfighting capabilities the military services expect" for an additional 15 months. This means that the jets are unlikely to be ready until August 2016, at the earliest, instead of what had been a July 2015 deadline.
from The Great Debate:
Counterterrorism: Where are Obama's policy changes?
It is now roughly five months since President Barack Obama announced a new direction for U.S. counterterrorism strategy.
from The Great Debate:
Saving Defense dollars: From BRAC to ORAC
While the government shutdown continues because of the Democrats' and Republicans' profound disagreement, the real issue facing the nation is something that both parties agree on, in principle: the need to reduce the size of the federal deficit.


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Orthopedic doctors suggest ATV safety
Posted: 09/17/2014 - ATV riding can be a popular outdoor activity during the warmer months, but it can also be a dangerous one.
Posted: 09/17/2014 - ATV riding can be a popular outdoor activity during the warmer months, but it can also be a dangerous one.
Posted: 09/17/2014 - A prescribed burn in our area could create quite a bit of smoke over the next few days.
Posted: 09/17/2014 - Marijuana activists in Colorado are tackling old stoner stereotypes in a new ad blitz aimed at promoting moderation and the safe consumption of pot.
Posted: 09/17/2014 - Republican gubernatorial challenger Bob Beauprez has jumped ahead of Colorado Democratic Gov. John Hickenlooper by 10 points in a new poll in a race that has been deadlocked in previous surveys.
Updated: 09/17/2014 - According to Montrose County officials, an investigation is ongoing after officers were dispatched on a report of shots fired and vehicles were seen fleeing the scene.
Posted: 09/17/2014 - The holiday season is still a few months away, but some people seeking jobs may be able to get an early gift
Updated: 09/17/2014 - A woman said to have committed welfare fraud has been caught after nine years of allegedly receiving illegal benefits from the Department of Human Services.
Updated: 09/17/2014 - A Western Slope drug coalition aims to change public perception about marijuana's effects on youth.
Updated: 09/17/2014 - A professional athlete is in hot water for child abuse after what he said is a form of discipline he grew up with, but how far is too far when it comes to punishing your kids?
Updated: 09/17/2014 - Food Bank of the Rockies is asking people to join in to help solve hunger around the state.
Updated: 09/17/2014 - Thermal imagers use infrared technology to show firefighters temperature and people they wouldn't otherwise be able to see in smoke-filled rooms.
Updated: 09/17/2014 - The City of Grand Junction is seeing positive signs for the economy after August sales tax revenue's show a huge increase.
Updated: 09/17/2014 - The Colorado School Safety Resource Center held a workshop for school administrators and teachers to address the issue of bullying in and out of school.
Updated: 09/17/2014 - A naturalization ceremony brought 50 people to celebrate the end of their journey to citizenship at the Colorado National Monument on Tuesday.
Posted: 09/16/2014 - The parents of a woman killed in the Colorado theater shootings are suing four online retailers they say sold ammunition, tear gas and equipment used in the attack.
Posted: 09/16/2014 - Colorado Democratic Gov. John Hickenlooper again raised more money than Republican challenger Bob Beauprez in the latest reporting period covering two weeks
Updated: 09/17/2014 - A teenager is in custody after an incident with police Tuesday morning, resulting in non-life threatening injuries to an officer.
Posted: 09/16/2014 - The White House says Biden will be in Denver on Friday for an event related to domestic violence.
Posted: 09/16/2014 - The Garfield County commissioners have voted to contribute $3 million toward construction of a new bridge across the Colorado River in Glenwood Springs.
Posted: 09/16/2014 - We have several arrests to tell you about over the weekend.
Posted: 09/16/2014 - Some kinds of homemade hash oil could be banned in Denver.
Posted: 09/16/2014 - City council members and downtown business owners tour the Avalon Theatre before its grand opening.
Updated: 09/16/2014 - The Transcontinental Motorcycle Cannonball Run made a pit stop in Grand Junction on Monday evening during their coast to coast ride.
Updated: 09/16/2014 - Medications prescribed treat pain, anxiety and blood pressure are the most common pills to blame for childhood overdoses that lead to emergency room visits
Updated: 09/16/2014 - This is the second year the Western Colorado Chamber of Commerce has coordinated seven weeks of events for the national celebration.


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Re: Border crossing
no, I don't think so? paper work, file, photos, paper work, 22 usd, I didn't have a problem and there are some agent there that will speed you through for a fee.
cheers tommy x
Re: Border crossing
The procedures are very straight forward but it can be a very muddy affair in this part of the country that time of year and getting up through Cambodia could take you some time as you often have floodings there that time of year.
Re: Border crossing
I'm not sure who says it's "bad". But when i did it a few years ago, when it wasn't sure you could get the visa-on-arrival for Cambodia, it was fine. Sure, it's a little more 'rustic' than some crossings, but still super straight forward.
Re: Border crossing
As bad as who says? I did it Visa on Arrival a few years ago and it was a breeze. Perhaps half an hour to forty minutes at the border to get the whole busload processed. Looking at the details on your profile I am guessing you are travelling on a Sri Lankan passport. Have a look at the Cambodian Government website and it will tell you the full story. Obviously, you need to cross at the main crossing point but it really was no problem.
- 1


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Star Cruises Ships
Star Cruises Ship Reviews
Ranked #1 of 2 Star Cruises Ships
- Menus featuring Chinese, Indian, Thai, Malaysian fare
- Kuala Lumpur-based line sails short Asia cruises
- No tipping policy (unless you feel like you must)
- Launched: 1988/2005; Passengers: 1,480
Ranked #2 of 2 Star Cruises Ships
- Offers a real taste of the Far East with its itineraries
- No gratuity charge
- 360-degree views from a large windowed observatory area on Deck 12
- Launched: 1999; Passengers: 1,960
Star Cruises Member Reviews
We are a group of five with 3 elderly people staying in two cabins. We chose this cruise because it is on special offer, for about US$300 per ... Read more
If you are not Asian this is not the ship for you. Star Virgo has been turned into a ship catering predominantly to the Asian to gamble. Norma ... Read more
We have sailed on many cruise lines over the years and last year travelled on this same ship when she departed from Singapore. We chose to sail ... Read more
Star cruise operates several cruises around South East Asia catered mainly for passengers from Singapore, Malaysia and Hongkong. Some of these ... Read more
We have sailed on Virgo many times over the years but not for 18 months so we were interested to see what if anything had changed. Embarkation was ... Read more
Write a Review!


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Elan Corporation, plc (NYSE:ELN) today announced that it has agreed to restructure the Tysabri® collaboration with Biogen Idec. Under the terms of the agreement, Elan will move from the current 50:50 business collaboration to an upfront payment of $3.25 billion and a double digit tiered royalty structure for the complete asset.
Highlights of Transaction Upon Closing:
- Up front cash payment of $3.25 billion to Elan
- First 12 months: royalty of 12% of Tysabri global net sales (all indications)
- Tiered royalty structure after 12 months
- 18% on up to $2 billion of global net sales (all indications)
- 25% on over $2 billion of global net sales (all indications)
- Biogen Idec will have full ownership and control of Tysabri
- Current 50:50 collaboration will terminate
- Provides tax efficient capital and long term cash flow to Elan
Elan's CEO, Kelly Martin, commented "This transaction enables Elan and its shareholders to realize, upon close, a meaningful percentage of the current value of Tysabri while maintaining long term cash flow realization through the multi-tiered royalty structure of the complete asset.
Mr. Martin added, "The restructuring of this business collaboration provides Elan with significant strategic flexibility. Future actions will be guided by our consistent and multi-year approach of dynamic risk/reward assessment of business opportunities. We are enthusiastic about the market opportunities around the globe and remain flexible and creative about the manner in which we would participate in those opportunities.""Upon close, this highly unique platform provides us with the financial resources to create an enterprise that will diversify its assets, generate future income, maintain specific science and clinical translational capabilities, and leverage the financial and business structure from being a 40 year Irish plc."


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Deltek CMO Kevin Iaquinto Named 2013 SmartCEO Executive Management Award Winner
Mr. Iaquinto joins top Washington area executives as winners of SmartCEO´s Executive Management Awards program
Herndon, VA (PRWEB) March 21, 2013
Deltek, Inc., the leading global provider of enterprise software and information solutions for government contractors and professional services firms, today announced that Kevin Iaquinto, Chief Marketing Officer at Deltek, has been named winner of the Greater Washington SmartCEO 2013 Executive Management awards. The Executive Management Awards program recognizes the best of Greater Washington´s management all-stars including chief financial officers, chief information officers, chief technology officers, chief operating officers and other executive officers. Iaquinto joins several dozen top executives being recognized in 2013.
The Executive Management Awards recognize the achievements of Greater Washington´s management all-stars for their creative management vision, leadership philosophy, innovative strategy and undeniable work ethic. The 2013 award winners collectively generate over $2.58 billion in annual revenue and employ over 14,400 individuals. This year´s winners will be recognized in the March issue of SmartCEO magazine and honored at an awards ceremony with over 350 local C-level guests on March 21, 2013 at the Fillmore Theater in Silver Spring, MD.
"All too often, senior leaders in an organization become unsung heroes. This is why SmartCEO designed the Executive Management Awards. The 2013 EMA winners are not only taking their companies and co-workers to new heights, but they are also leaders within the communities where we work and live," says Jaime Nespor, group publisher of SmartCEO magazine, "We are honored to award each of these individuals and tell the stories of their achievements and contributions."
"Kevin is very deserving of being recognized as one of the region´s top executives and best CMOs. We are extremely proud of Kevin, and this award is a tribute to his hard work and creativity," said Mike Corkery, president and CEO at Deltek. "As a key member of the executive team, Kevin has played a critical role in transforming the Deltek brand and significantly increasing market awareness and demand for our solutions. Kevin and his highly skilled marketing team have helped grow our company into a global market leader with 16,000 customers in over 80 countries around the world. On behalf of Deltek and our employees, I´d like to congratulate Kevin on being named a 2013 Executive Management Award recipient."
About SmartCEO
SmartCEO is an exclusive community of CEOs and business executives, highly regarded mentors and well-respected thought leaders whose experiences benefit their own organizations and the communities in which they serve. SmartCEO´s mission is to educate and inspire the business community through the pages of our award-winning magazine, connections at our C-level events and access to valuable online resources. For more than a decade, SmartCEO has been a leader in helping CEOs tell their stories in-print, in-person and most recently in-video. SmartCEO´s Mid-Atlantic focus began in Baltimore and has grown to include Philadelphia, Washington DC, and has recently expanded to New York City.
About the Executive Management Awards
The Executive Management Awards highlight chief executives who have gone above and beyond to support their organizations' initiatives. SmartCEO profiles chief executives in the Mid-Atlantic in four categories: CFO, CIO/CTO, COO and CXO. SmartCEO accepts award applications online and via email, which are reviewed by an independent panel of business leaders who select winners based on the quality of the nominations. Each year, the winners are profiled in Washington SmartCEO magazine and celebrated at an awards reception in March.
About Deltek
Deltek is the leading global provider of enterprise software and information solutions for professional services firms and government contractors. For decades, we have delivered actionable insight that empowers our customers to unlock their business potential. 16,000 organizations and 2 million users in over 80 countries around the world rely on Deltek to research and identify opportunities, win new business, optimize resources, streamline operations, and deliver more profitable projects. Deltek — Know more. Do more.® http://www.deltek.com
Follow us on Twitter @Deltek or fan us on Facebook at http://www.facebook.com/deltekinc
For the original version on PRWeb visit: http://www.prweb.com/releases/prweb2013/3/prweb10553318.htm


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|Property type
|Minimum Stay
|7 nights
Mbali Lodge is a luxurious private family home, owned and managed by me, it is NOT owned by the estate. Set in the serenity and breathtaking beauty of Table Mountain's nature reserve, it is just minutes from the Cape's famous beaches, vineyards, restaurants and exclusive shopping. There is plenty to suit all tastes here. Set in a 50 acre private estate with 24 hour security, Mbali (meaning 'flower' in Zulu) has scenic mountain trails to explore on the doorstep and the country's oldest vineyards just down the road, as well as Hout Bay's long sandy beaches. Meanwhile the buzz of Camps Bay, the V&A Waterfront and central Cape Town are all within easy reach. Excellent cafés and restaurants abound nearby in case you do not feel tempted by Mbali Lodge's fully equipped modern kitchen or its smart built-in braai (barbecue) by the private lap pool. Three beautiful bedrooms (each with its own bathroom), and stunning open plan living and dining give on to a wide wooden deck - the perfect spot for enjoying a glass of the Cape's best. Mbali lodge is owned and managed privately, it is NOT owned by the estate.
Inside: Bedroom 1: has a king size bed and access to main deck. Its en suite bathroom has a free standing bath, glass roofed shower room with a view to the sky, WC and basin.
Bedroom 2: comes with double size bed on a mezzanine floor with its own deck, own bath, WC and basin.
Bedroom 3: is on a lower level, has a queen size bed with access to a deck and garden, its own shower, WC and basin.
On the main floor, there is a spacious open plan living room with elegant stand-alone fire place, large comfortable sofas and arm chairs, television . The dining area has a table to seat 8. There are extensive views and sliding doors to access the main deck. The fully equipped modern kitchen comes with cooker, electric hob, fridge, freezer, dishwasher, full dinner service for 8, glassware, utensils, cooking pots and water filter, and is directly off the dining area. Downstairs, there is internal access to the garage (with remote opener) and washing machine and tumble dryer.
There is a small charge for an internet service.
Please note families with small children, that there are stairs, a large deck and an open pool.
Outside: Mbali Lodge has its own landscaped garden and is part of a 50 acre private estate with nature trails literally on the doorstep. There is outdoor furniture on the deck, a built in braai (barbecue) by the 12m solar heated lap pool. There is plenty of outdoor lighting perfect for alfresco dining on warm evenings. The house, while very peaceful, is not isolated and has neighbours who are also part of the Silvermist Estate.
Additional Services: Towels and linen are included. The property is cleaned on a weekly basis and all linen changed. Additional house keeping service is available on request. Gardener and pool maintenance are also included.
The estate is an exclusive gated property with 24 hour security. Mbali Lodge also has its own user-friendly alarm system.
Having spent my childhood in Africa, i left as a young woman to travel the world and never went back. However, when the opportunity to build a house at the back of Table Mountain came along, it seems that the time was right to return. Mbali lodge is for me, each time i go there, my own 'out of africa' experience. Its very much my dream and have tried to make it into a comfortable, welcoming and fun place to share with my family and hopefully yours as well.
Lorna King purchased this house in 2010
Mbali lodge is set high up on the back of Table mountain, the view is stunning. It feels as though we are miles from anywhere, when in fact we are within a short drive from the city, 20 mins to central cape town, 10 to beaches and 3 minutes to the oldest vineyards in the cape.
We can walk from our back door up the mountain, or drive a few minutes to the beach. We are also on the Constantia Wine Route, only minuets from our door. If you are really feeling lazy, the pool is a great place to relax around.
We had a wonderful stay in your beautiful house, with lots of wildlife for company.
Love the views and area and hope to return soon.
A wonderful holiday in a stunning location. The house is beautifully maintained and furnished with everything one could want for a comfortable and memorable stay. Waking up to views of Table Mountain outside my window was one of the highlights. Others were visiting wineries, great restaurants, friendly cafés, lovely beach close by and fun shopping. I would definitely recommend this property.
Jill Ziemer
It is difficult to overate the retreat as it has so many outstanding features. The tranquil site, superb 'boutique hotel' facilities, the panoramic views, great walking trails all make Mbali a wonderful base for a restful holiday. An added bonus is that the house is situated just forty minutes drive from the international airport. The close proximity of Hout Bay, Kirstenbosch, the vineyards and Cape Town provides a huge range of cultural and culinary delights to enjoy. Mbali is a beautifully furnished and immaculately maintained property. We would have no hesitation in recommending it to friends.
Mbali Lodge couldn't be in a better location if you are looking for a relaxing holiday in the midst of beautiful enchanting mountain scenery, good restaurants within easy reach in and around the vineyards of Constantia Valley and in a gated nature reserve. It is very comfortable and well-equipped, stylish and very well-maintained. I would readily recommend it to friends and family without doubt.
Mbali Lodge is a beautiful house set in the hills between Constantia & Hout Bay and thus ideally located to explore both Cape Town as well as the total Cape area. With it secure gated & supervised entrance you feel very safe. The house provides all the comforts that you need and especially liked the swimming pool which has a nice size. The managing company was very responsive to any problem and made us feel very welcome. All in all a very good house at a good location which was very well cleaned and maintained.
I don't normally write reviews, but Mbali lodge is such a breathtaking, beautiful place I can't recommend it highly enough. SItuated in picturesque Constanzia Nek, the views look onto table Mountain in all its dramatic glory. Some of the finest vineyards South Africa have to offer are conveniently close, as are the beaches and amazing restaurants. The lap pool was perfect for a morning swim, or nice to have a dip whilst enjoying our braii (also known as the BBQ). The interior design is impeccable. From the hand-painted fabrics on the lounges and curtains, to the tastefully-selected African art- the general attention to detail really is astounding. Books and games are also provided (we did have a 5 hour game of South African Monopoly, that was epic!). The outside shower of the master bathroom is possibly my most favourite shower that I've ever used. Open, yet protected - it offers a chance to enjoy the location yet with the utmost privacy. Definitely a place I'd like to go back and stay. Thank you so much for sharing your home with us.
This house is a perfect base for a stay in Cape Town. We enjoyed the tranquility of the setting - beautiful views and peaceful but also very close to all the local attractions. The layout of the house was perfect for our family of 5. It is beautifully decorated, with comfy sofas and beds. We would definitely stay here again if we ever make it back to Cape Town. We all wish we were still there!
The safe, sandy swimming beaches of Hout Bay are just 10 minutes drive from Mbali Lodge in one direction. Meanwhile, the Constantia Wine Route starts at the bottom of Silvermist Estate where Mbali Lodge is situated. There is exclusive shopping, boutiques and banking available in Constantia while Hout Bay has a wide range of High Street stores, supermarket, banking and a small mall (where you can purchase credit on the PAYG phones readily available on arrival at Cape Town airport.) The vibrant V&A Waterfront and Cape Town central city is an easy 20 minutes away while there are plenty of scenic routes to follow too - Chapman's Peak being one of the most dramatic.
Nature trails and hiking are literally on the doorstep of Mbali Lodge, on the Table Mountain Nature Reserve.
Other Activities: clifton is 20 minutes drive kirstenbosch botanical gardens is 5.5km
Golf: Steenberg Golf Club is rated as one of the top 3 golf courses in South Africa.
Alternatively, the Royal Cape and Westlake Golf Courses, also highly rated, are very nearby to Mbali Lodge.
|Rental Period
|Minimum Price
|Additional Nights
|Weekend Night
|Event Price
Rate 2
1 Apr 2015 - 30 Sep 2015
7 night minimum stay
for 7 nights
Rate 3
1 Oct 2015 - 13 Dec 2015
7 night minimum stay
for 7 nights
Rate 4
14 Dec 2015 - 4 Jan 2016
7 night minimum stay
for 7 nights
My Standard Rate
7 night minimum stay
for 7 nights
|No additional mandatory fees
|Refundable Damage Deposit
33 1/3% deposit to be paid to confirm booking. To be paid immediately on receipt of booking form.
The balance to be paid 6 weeks prior to arrival.
rental rates are in South African Rands.
Please enquire for longer or shorter stays.
Monthly rates are negotiable.
The booking form will have details of our cancellation policy.
Rates are subject to change until reservation is confirmed.
Please Note: The owner of this property accepts payment in the original currency specified (ZAR), before use of conversion tool. The conversion tool is provided for your convenience only. The owner may accept other currencies if specifically agreed in advance.


text:
CCBA to Host 25th Annual Meet Your Judges Mixer
SPECIAL EVENT UPDATE: For those people who placed their order BEFORE 5/29/2015 for tickets to this event (and who are local to Las Vegas area and not a judge or their guest), please note that your tickets will be packaged for delivery to you before 6/4/2015. For those who order tickets AFTER 5/29/2015 and BEFORE 6/4/2015, then your ticket will be at "will call" table for pick up when you arrive at the event. Thank you all for your patience and support of our non-profit organization!
Clark County Bar Association presents
25th Annual Meet Your Judges Mixer
Date: Thursday, June 4, 2015
Time: 5:30-8:30 p.m. Doors open at 5:30 p.m.
Location: The Mob Museum, 300 Stewart Ave, Las Vegas, NV 89101, Las Vegas
All members of the Nevada Bar and Bench, their staff, and the legal community are invited to attend this special event.
Enjoy appetizers, desserts, and cool refreshments while networking in one of the valley's most historic settings. Event highlights to include a trivia game about the National Museum of Organized Crime & Law Enforcement™. This event provides an opportunity for members of the legal community meet in social setting. Please attend to meet Nevada judges, catch up with colleagues, and make new contacts.
This private event is open to judges (local, state, and federal), attorneys, legal assistants, legal secretaries, law students, and merchants. Attendance levels at past events average 600 people. Business casual attire acceptable.
This is a cocktail reception; no minors allowed. Please note more restrictions listed below.
Ticket* prices: $45/CCBA Member and $75/Non-member
To attend this event, please register using one of the following methods:
- Register online (via Constant Contact)
- Fax or mail PDF form to CCBA: CCBA-MYJ-2015-Reg-Form
- Call CCBA at 702-387-6011 between 8 a.m. and 4 p.m. Monday-Wednesday, June 1-3, 2015.
*Please note these restrictions:
- THIS IS A TICKETED EVENT. No ticket, no entry, no exceptions. Ticket orders made through May 29, 2015 will be filled and delivered to purchaser. The Clark County Bar Association is not responsible for lost or stolen tickets.
For ticket orders made AFTER May 29, 2015 but BEFORE June 4, 2015, CCBA will hold purchased tickets at the event registration table. Without prior registration, there is an additional $15 fee to be charged upon check-in at the event.
Registration will be refunded minus a $15 processing fee for all written cancellations, including return of tickets, received by Friday, May 29, 2015. No refunds will be issued after May 29, 2015.
Get all the event details on our Special Events page…|
CCBA New Lawyers Committee Highlights
The New Lawyers Committee consists of attorneys admitted to practice in Nevada within the last five years regardless of age. In addition to publishing the Lawyer's Survival Guide, producing CLE seminars of special interest to new attorneys, hosting networking and social events for new attorneys, and volunteering at CCBA events such as the Meet Your Judges Mixer, the New Lawyers Committee works closely with the William S. Boyd School of Law's Society of Advocates to coordinate volunteers for law school competitions.
Highlights from Recent William S. Boyd School of Law Competitions
From January through April, 2015, the New Lawyers Committee aided in the organization of the Eighth Annual In-House Negotiation Competition and the Seventeenth Annual Moot Court Competition.
On January 30, 2015, twenty-two student teams competed in the Eighth Annual In-House Negotiation Competition, which was held at the William S. Boyd School of Law. The Bank of Nevada generously provided cash prizes to the members of the top three teams:
- First Place: Andrea Orwoll & Michael Viets, recipients of a $200.00 cash prize
- Second Place: Jonathan Chung & John Mowbray, recipients of a $150.00 cash prize
- Third Place: Andrew Coats & Todd Weiss, recipients of a $100.00 cash prize
On April 24 and 25, 2015, seventy-five students participated in the Seventeenth Annual Moot Court Competition, which was held at the William S. Boyd School of Law. On the second day of the competition, the four student finalists competed for cash prizes provided by the Bank of Nevada and BARBRI scholarships provided by BARBRI.
- First Place: Michael Viets, recipient of a $150 cash prize and a $1,000 BARBRI scholarship
- Second Place: Aarin E. Kevorkian, recipient of a $100 cash prize and a $1,000 BARBRI scholarship
- Third Place: Garrett Chase, recipient of a $75 cash prize
- Fourth Place: Emily Ross, recipient of a $50 cash prize
Special thanks to all who volunteered!
The New Lawyers Committee and the Clark County Association wishes to extend thanks to the volunteers who made these competitions a tremendous success:
|Boyd Law Competition Volunteers
|Michelle Alarie
|Crystal Eller
|Natalie Lehman
|Chad Schatzle
|Erik Aldrian
|Frank Ellis
|Mark Lerner
|Adam Schneider
|Melissa Alessi
|Michael Esposito
|Jeffrey Luszak
|Jeffrey Segal
|Elizabeth Ashley
|Abe Flores
|Karissa Mack
|Marisa Shapoval
|Jae Barrick
|Kylie Foster
|Theresa Mains
|Alina Shell
|Travis Barrick
|Mark Gentile
|Judge Janiece Marshall
|Matthew Sibert
|Liane Binowitz
|Greg Gordillo
|Michael McKellab
|Marsha Stephenson
|Brian Blaylock
|Saman Heidari
|Nadine Morton
|Jaimie Stilz-Outlaw
|Judge Richard Boulware
|Lawrence Hill
|Jared Moser
|Kelly Stout
|Lauren Calvert
|Michael Hughes
|Lydia Nussbaum
|Anita Webster
|Patrick Chapin
|Josh Igeleke
|Judge Vincent Ochoa
|Brenda Weksler
|Benjamin Childs
|Amy Ismail
|Casey Perkins
|Amber White-Davidson
|Miles Clark
|Joni Jameson
|Robin Perkins
|Lynsey Williams
|Jamie Combs
|Brandon Kemble
|Justice Kristina Pickering
|Cayla Witty
|Judge Kenneth Cory
|Samuel Kern
|Brian Ramsey
|Alejandro Yanez
|Dana Cotham
|Judge Bita Khamsi
|Jennifer Roberts
|Kristopher Zeppenfeld
|Andrew Craner
|Pooja Kumar
|Esther Rodriguez
|Judge Cynthia Cruz
|Elham Khomassi
|Michael Saltman
|Judge Jennifer Dorsey
|Paul Lal
|Eduardo San Miguel
Michael Hughes serves as the Chair of the CCBA's New Lawyers Committee. Michael is an attorney at the law firm of Cohen-Johnson, LLC.| Tags: New Lawyers Committee
Standard Bail Schedule Updated for Las Vegas Justice Court
On May 21, 2015, the Las Vegas Justice Court has released an updated Standard Bail Schedule for felonies, gross misdemeanors, misdemeanors, violations of protection order, and additional penalties. The schedule is effective May 26, 2015. As such, beginning at 6:00 a.m., Tuesday, May 26, 2015, the Clark County Detention Center will utilize the new bail schedule for all new CCDC bookings.| Tags: criminal law, Las Vegas Justice Court
Clark County Seeks Proposals from Law Firms to Provide Civil Defense Legal Services
Clark County is soliciting submittals from qualified firms/agencies to provide civil defense legal services to Clark County. Clark County is seeking outside legal counsel with qualifications to give legal advice and civil litigation representation of Clark County and its employees in any of the following practice areas:
- Civil Rights Personal Injury/Tort Defense
- Employment Bankruptcy
- Eminent Domain General Contract Disputes
- Flood Litigation Construction Contract Disputes
- Public Utilities Commission Special Improvement District Litigation
- Real Property Transactions
Law firms interested in submitting a proposal to provide these services must complete the document, "STATEMENT OF QUALIFICATIONS, SOQ NO. 603696-15, CIVIL DEFENSE LEGAL SERVICES FOR CLARK COUNTY, NEVADA" See PDF file at http://www.clarkcountynv.gov/Depts/finance/purchasing/Bid_Documents/603696_abb.pdf.
Those who wish to propose their services should note the following tentative schedule set by the county:
- Last Day to Ask Questions: May 29, 2015
- Last Day County Will Provide Addendum: June, 3, 2015
- Proposal Due Date: June 10, 2015 3:00 p.m. Pacific
- Final PROPOSER Selection: June, 2015
- Award & Approval of the Final Contract(s): July 21, 2015
To get all the details, visit the Clark County's website at http://www.clarkcountynv.gov/depts/finance/purchasing/Pages/listingdetails.aspx?bidID=1337.| Tags: Clark County, Nevada
Bar Luncheon to Feature Nevada Attorney General Laxalt
Event registration extended to Noon, Wednesday, May 20, 2015!
Join us on Thursday, May 21, 2015 from Noon to 1 p.m. for a luncheon at the Las Vegas Country Club with featured speaker Nevada Attorney General Adam Paul Laxalt. Laxalt's presentation will include information about the Attorney General's Advisory Committee for the Office of Military Legal Assistance. Entrée choices are Ginger Orange Grilled Salmon, Pesto Grilled Chicken Breast, and Pasta Caprese. Check-in starts at 11:30 a.m. outside the LVCC's main dining room.
To attend this event, please register by Noon, Wednesday, May 20, 2015 using one of the following methods:
- Register online (via Constant Contact)
- Fax or mail registration form to CCBA.See PDF: CCBA-Luncheon-May-21-2015
- Call CCBA at 702-387-6011 (8am-4pm, Monday-Friday)
|Luncheon Sponsor
Note: All reservations to CCBA events must be pre-paid. Each person who arrives without a prior reservation will not be guaranteed a seat, a meal, or entry to the event. If space becomes available to accommodate the unexpected person, then there will be an additional fee of $15 in addition to the listed price to attend. To receive a full refund for cancellations, a written request must be made to CCBA 72 hours prior to the luncheon.| Tags: Military Legal Assistance, Pro Bono
Administrative Order Regarding Matters of Electronic Recording of Courtroom Proceedings in Juvenile Cases at Eighth Judicial District Court
On May 7, 2015, the Eighth Judicial District Court filed an order in the matter of electronic recording of courtroom proceedings in juvenile cases. In Administrative Order 15-05 (AO 15-05), the court addresses the conditions and concerns for how electronic proceedings in juvenile dependency and juvenile delinquency cases may be opened to inspection or released only to the attorneys of record or by court order to persons who have a legitimate interest in the records. The court further ordered the clerk of the court to develop policies and procedures to ensure that electronic recordings of all juvenile proceedings are not disseminated without compliance with the order as well as conditions for their release. See Administrative Order 15-05, a PDF document.| Tags: Eighth Judicial District Court, juvenile law
New Administrative Order to Address Misdemeanor Releases at Las Vegas Justice Court
On May 6, 2015, the Las Vegas Justice Court Chief Judge Joe Bonaventure signed an order (effective immediately) that addresses the condition for release of defendants who are arrested on one or more misdemeanor charges, and no gross-misdemeanor or felony charges. See Amendment to Administrative Order 15-05 (AO 15-05), a detailed four-page PDF document: 15-05-Misdemeanor-Releases-(Final)| Tags: criminal law, Las Vegas Justice Court, Las Vegas Justice Court Rules
Procedures Amended for Assignments of DUI and Vehicular Crime Cases at Las Vegas Justice Court
On April 21, 2015, the Las Vegas Justice Court ordered amendments (effective immediately) to the policies and procedures for the assignment of cases involving DUI cases and vehicular-crime cases. To read the detailed four-page document, download the PDF file: 15-03-DUI-Case-Assignments-(Amended-Final)
Related story (April 7, 2015): "Las Vegas Justice Court Changes Procedures for Assignments of DUI Cases," (April 7, 2015) https://www.clarkcountybar.org/2015/las-vegas-justice-court-changes-procedures-for-assignments-of-dui-cases/| Tags: Las Vegas Justice Court, Las Vegas Justice Court Rules
Procedures Amended for Assignments of Domestic Violence Cases at Las Vegas Justice Court
On April 21, 2015, the Las Vegas Justice Court ordered amendments (effective immediately) to procedures for the assignment of cases involving domestic violence. To read the detailed three-page document, download the PDF file: 15-04-DV-Case-Assignments-(Amended-Final)
Related story (April 7, 2015): "Las Vegas Justice Court Clarifies Procedures for Assignments of Domestic Violence Cases," https://www.clarkcountybar.org/2015/las-vegas-justice-court-clarifies-procedures-for-assignments-of-dv-cases/| Tags: Las Vegas Justice Court, Las Vegas Justice Court Rules
Eighth Judicial District Court Civil/Criminal Case Reassignment Effective May 4, 2015
Effective May 4, 2015, the Eighth Judicial District Court reassigned cases in conjunction with the arrival of its newly appointed district judges and as reflected in Administrative Order 15-03. The following reassignments and track changes are in effect:
- 1. Department 2's entire case load will be transferred to Department 15.
- 2. Department 15's entire caseload will be transferred to Department 2.
- 3. Department 2 will replace Department 15 in Track 8 of the Criminal Case Flow Model.
Attorneys should review the posted administrative order and the Odyssey electronic case management system for further specifics on the aforementioned transfers and to confirm upcoming hearing dates. In the event a party is eligible pursuant to Supreme Court Rule 48.1, he or she may exercise a peremptory challenge as a result of the case having been reassigned.
To read the full administrative order (AO 15-03), it is available as "May 2015 Civil/Criminal Case Reassignment" under "Court News" at http://www.clarkcountycourts.us. Questions can be directed to Assistant Court Administrator Timothy Andrews at (702) 671-3312.| Tags: Eighth Judicial District Court, Odyssey Case Management System


text:
Phase 1-2 Study of Onapristone in Patients With Advanced Castration-resistant Prostate Cancer
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This study will evaluate an extended-release (ER) formulation of onapristone in patients with prostate cancer in which Progesterone Receptor (PR) may be contributing to tumor progression. A companion diagnostic to select patients whose prostate cancer expresses the activated form of the PR (APR) is under development and will be implemented in this study; it may be used to further enrich the selection of the population based upon ongoing review of the results. Patients will be treated until occurrence of an intolerable safety issue, treatment failure, if patient elects to withdraw, or for non-compliance with either protocol-specified evaluations or onapristone treatment. An additional cohort of patients will be included at the recommended phase 2 dose to gain additional understanding of the onapristone safety profile and potential anti-cancer activity.
Prostate Cancer
Metastatic Prostate Cancer
Androgen-independent Prostate Cancer
Recurrent Prostate Cancer
Drug: onapristone
Phase 1
Phase 2
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|A Phase 1-2 Study of Onapristone in Patients With Advanced Castration-resistant Prostate Cancer
- Dose limiting toxicities related to onapristone utilizing a day 57 safety cut off and based on CTCAE v4 [ Time Frame: Baseline to 57 days post-first dose ] [ Designated as safety issue: No ]
- Response to onapristone [ Time Frame: Baseline to 30 Days after last dose ] [ Designated as safety issue: No ]
- Objective partial or complete response by RECIST 1.1, confirmed on a second CT scan at least 4 weeks apart
- and / or
- Conversion of circulating tumor cell count (CTC) from ≥5/7.5 ml blood to <5/7.5 ml blood nadir confirmed by at least two readings at least 4 weeks apart
- and / or
- PSA decline of ≥ 50% (according to the PCWG2).
- Safety and tolerability of extended-release onapristone tablets BID [ Time Frame: Baseline to 30 Days after last dose ] [ Designated as safety issue: No ]Safety will be assessed by physical exam, vital signs, monitoring of adverse events, changes in ECG, and changes in PSA and other clinical laboratory values.
- PK of onapristone, mono-demethylated onapristone and other metabolites in plasma and urine [ Time Frame: Baseline to 30 Days after last dose ] [ Designated as safety issue: No ]
|Estimated Enrollment:
|Study Start Date:
|February 2014
|Estimated Study Completion Date:
|December 2015
|Estimated Primary Completion Date:
|July 2015 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: onapristone 10 mg BID
onapristone 10 mg BID extended-release tablets
Drug: onapristone
Other Name: ZK 98299
Experimental: onapristone 20 mg BID
onapristone 20 mg BID extended-release tablets
Drug: onapristone
Other Name: ZK 98299
Experimental: onapristone 30 mg BID
onapristone 30 mg BID extended-release tablets
Drug: onapristone
Other Name: ZK 98299
Experimental: onapristone 40 mg BID
onapristone 40 mg BID extended-release tablets
Drug: onapristone
Other Name: ZK 98299
Experimental: onapristone 50 mg BID
onapristone 50 mg BID extended-release
Drug: onapristone
Other Name: ZK 98299
|Ages Eligible for Study:
|18 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Male patients, 18 years of age or greater;
- Histologically confirmed adenocarcinoma of the prostate (without neuroendocrine differentiation or small cell features). For Stage 2 of the study, PR expression in ≥1% tumor cells;
- Biopsy to determine current AR/PR and APR status
- Metastatic or recurrent inoperable disease after previous surgery, radiation therapy, and/or chemotherapy;
- No more than two prior chemotherapy regimens for CRPC (docetaxel rechallenge will be regarded as one line of chemotherapy);
- Disease that has progressed by PSA on abiraterone or enzalutamide as the last line of treatment. Ongoing androgen deprivation therapy with a gonadotropin releasing hormone (GnRH) analogue or orchiectomy (i.e., surgical or medical castration);
- Serum testosterone level < 1.7 nmol/L (50 ng/dL);
- Patients receiving bisphosphonate therapy must have been on stable doses for at least 4 weeks;
- Evaluable disease per RECIST 1.1 or Prostate Cancer Clinical Trials Working Group 2;
- ECOG performance status 0-2;
- Life expectancy ≥ 3 months;
- Willing and able to sign written informed consent.
Exclusion Criteria:
- Serum creatinine >1.5 ULN;
- On ECG a QTc(F) interval >480 msec or any clinically significant cardiac rhythm abnormalities;
Liver function tests documented within the screening period and/or at baseline:
- Total bilirubin > ULN (except in patients diagnosed with Gilbert's disease);
- Alkaline phosphatase > 2.5 x UNL, unless test for alkaline phosphatase isoenzymes is elevated only for bone isoenzyme;
- ALT/AST > UNL or > 2.5 x UNL in case of liver metastases;
- Absolute neutrophil count < 1,500/μL, platelet count < 100,000/μL, and hemoglobin < 5.6 mmol/L (9 g/dL) and no growth factors or blood transfusions within 7 days of these values;
- Serum albumin < 25 g/L (2.5 g/dL);
- Known positive virology/serology for HIV, HBV or HCV
- Chronic inflammatory liver condition. History or clinical evidence of any liver or biliary pathology;
Patients with any other prior malignancy are not allowed except for:
- Adequately treated basal cell or squamous cell skin cancer;
- Adequately treated Stage I or II cancer from which the patient is currently in complete remission;
- Other cancer from which the patient has been disease-free for 2 years;
- Chronic adrenal failure or is receiving concurrent long-term corticosteroid therapy
- History or clinical evidence of any surgical or medical condition which the investigator judges as likely to interfere with the results of the study or pose an additional risk in participating;
- Used any prescription medication during the prior 2 weeks that the investigator judges is likely to interfere with the study or to pose an additional risk to the patient in participating;
- Received an investigational product or been treated with an investigational device within 30 days prior to first drug administration, or plans to start any other investigational product or device study within 30 days after last drug administration;
- Received any of a number of specific anti-cancer therapies with known efficacy within predetermined timeframes prior to receipt of first dose of study drug, without withdrawal response and with no plans to initiate any of these during study;
- Concurrent use of herbal products that may decrease PSA levels (e.g., saw palmetto);
- Residual toxicity of prior anticancer treatment > grade 1 except for alopecia;
- Brain metastases, active epidural disease or spinal cord compression, unless treated at least 4 weeks before entry, and stable with steroid treatment for ≥1 week;
- Paget's disease of the bone;
- Structurally unstable bone lesions suggesting impending fracture;
- Patients with reproductive potential not employing adequate contraception during treatment and for 1 month after completing treatment;
- Lack of physical integrity of the upper gastrointestinal tract, malabsorption syndrome, or inability to swallow pills;
- Mental incapacity or language barriers precluding adequate understanding, cooperation, and compliance with the study requirements;
- Is, in the judgment of the investigator, unable or unwilling to comply with the requirements of the study.
Please refer to this study by its ClinicalTrials.gov identifier: NCT02049190
|Contact: Joseph Bisaha
|United Kingdom
|Inst of Cancer Research & Royal Marsden NHS Foundation Trust
|Sutton Surrey, United Kingdom, SH2 5NG
|Contact: Gerhardt Attard, MD, PhD, MRCP (+44) 020 872224137 firstname.lastname@example.com
|Sub-Investigator: Johann S De Bono, MD, PhD, MSc, FRCP
|Sub-Investigator: Joaquin Mateo, MD
No publications provided
|Responsible Party:
|Arno Therapeutics
|ClinicalTrials.gov Identifier:
|NCT02049190 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 28, 2014
|Last Updated:
|December 8, 2014
|Health Authority:
|United Kingdom: Medicines and Healthcare Products Regulatory Agency
Keywords provided by Arno Therapeutics:
Advanced Prostate Cancer
Castration-resistant Prostate Cancer
Prostatic Neoplasms
Genital Neoplasms, Male
Urogenital Neoplasms
Neoplasms by Site
Genital Diseases, Male
Prostatic Diseases
Additional relevant MeSH terms:
Prostatic Neoplasms
Genital Diseases, Male
Genital Neoplasms, Male
Neoplasms by Site
Prostatic Diseases
Urogenital Neoplasms
Antineoplastic Agents
Fertility Agents
Fertility Agents, Female
Hormone Antagonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Pharmacologic Actions
Physiological Effects of Drugs
Reproductive Control Agents
Therapeutic Uses
ClinicalTrials.gov processed this record on May 21, 2015


text:
Gov't holds PPP invest briefing
popular .
Amid all the criticisms it has gotten for the slow pace at which it is implementing infrastructure projects, the government is giving its flagship public-private partnership program another push with an investment briefing for potential investors on Monday.
According to the Department of Trade and Industry, Monday's briefing "will give an overview of opportunities in infrastructure development, particularly in PPP, which aims to raise the profile of PPP not only in the context of direct opportunities but also in harnessing the potential of PPP to boost the construction industry in the country."
Also to be discussed are the rules of engagement for the engineering and construction projects that will be presented to interested investors today.
Trade and Industry Secretary Gregory Domingo and Undersecretary Cristino Panlilio, Public-Private Partnership Center executive director Eleazar Ricote and Bases Conversion and Development Authority president and chief executive Arnel Paciano Casanova will be making the project presentations on behalf of the government.
Also attending the event are United Kingdom Foreign and Commonwealth Office Minister Jeremy Browne and Philippine Constructors Association incoming president Augusto Manalo.
The government launched the PPP program last year, shortly after the start of the Aquino administration's term.
Ten big-ticket infrastructure projects were lined up as priority projects, with the operations and maintenance contract for the EDSA Metro Rail Transit 3 and the Light Rail Transit Line 1 scheduled to be auctioned first.
While the bidding was opened to potential investors and several groups have already expressed interest in participating, the submission of bids was shelved when losing vice presidential candidate Manuel Roxas II took over the helm of the Department of Transportation and Communications (DoTC).
The government's plan for the MRT-3 and LRT-1 O&M contracts continued to remain unknown as the DoTC had yet to make its recommendation.
Finance Secretary Cesar Purisima had earlier said the O&M contracts were currently being prepared for bidding. He later backtracked on his statement, saying he did not want to preempt the results of the review being conducted by the DoTC on the projects.
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text:
With various groups linking him to all sorts of prophecies, it looks like it's open season on Kiichi! Saku's ready to turn him over to the Researchers. Saame believes his clan will regain their legendary wings with the help of an Oni. Meanwhile, all of Kiichi's traveling companions seem to be gaining extra powers. Speaking of "extra," how will Kiichi handle three horns instead of one?
Story and art by Taka Amano.
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Posada de Colores Apartments2221 Fruitvale Ave, Oakland, CA 94601 View On Map (510) 534-6200
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Panthers lose guard Williams for year
The Panthers announced that starting right guard Garry Williams has torn the ACL and MCL in his left knee and will miss the remainder of the season.
SIDELINE PRINCESSESThey're fit, they're pretty and we can't get enough of them. Check out the the 2013 NFL cheerleaders.
The news came Monday shortly after coach Ron Rivera addressed the media at his weekly press conference.
The injury occurred in the first half of Carolina's 12-7 loss to Seattle after a Seahawks defensive lineman rolled up on Williams' leg.
The five-year pro won the starting right guard spot in training camp prompting the Panthers to release veteran guard Geoff Hangartner.
Rivera said earlier Chris Scott would likely replace Williams at right guard.
It's Williams' second major injury.
He broke his ankle in Carolina's final preseason game in 2011 after earning a starting spot earlier that summer.
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NFL Headlines
NFL Insiders: Dolphins name Dennis Hickey new general manager
Carroll: Seahawks CB Richard Sherman sorry about postgame rant
Browns to interview Bills' Pettine with Broncos' Gase out of running
NFL talking to 49ers about sideline hit vs Seahawks in NFC title game
Falcons hire former Chiefs GM Pioli as assistant general manager


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Hey so gamefly is having a sale on Syndicate for PC. I'm gonna pick it up. It does use origin. Do we have A PC giantbomb Syndicate? Btw the link is http://www.gamefly.com/Download-Syndicate/5000401/
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If you have the money there's pretty much no reason to not do this. What's $5? A trip to a fast food place? Don't be silly, buy a great game instead.
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$5 too much.
@zenmastah: I should have mentioned it states the sale is for Canada and the US only.
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Would like to buy this but right now i cant out of principle, i just have too many unfinished games. 5 dollars is a good deal though
I had bought it at $6.50 awhile ago. 45 minutes after playing, I regretted even a $1 spent on it. Terrible awful lighting effects (maybe they confused the flash bang effect with normal lighting source), map design, encounter design, shooting feel, and story.
Though it is difficult to make co-op horde mode type gameplay completely flat, so maybe that is decent.
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show up 15 pounds for me..damn
Same. :/ Though it's always been around £5 or less on Amazon when I've checked so I might bite anyway.
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so either jeff is off his gourd or he's the only one who really knows what's what.
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$5 too much.
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I just did it. Pumped to play it after hearing so much good stuff about it from GB.
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Wouldn't play it for free
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Oh yeah, you just reminded me I own this. I tend to forget about Origin games I pick up on sale.
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I personally liked the game. Umm... did anyone else find the DART voice kinda hot?
Not the worst game in the world, but it definitely caught at a bad time when a ton of 4 player co-op games were coming out and Resident Evil O:RC was one of them, got all the hype and turned out to be a terribad game which burnt alot of folks. That and all the old-school Syndicate fans had a DMC sized hissy-fit that it was an FPS. If you're looking for co-op and doing the same missions over and over again, you'll get some enjoyment, but the story is pretty much nonsense and it's really short.


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Zdislava Berka
|This article includes a list of references, related reading or external links, but its sources remain unclear because it lacks inline citations. (August 2014)
|Zdislava of Lemberk
Saint Zdislava and Saint John Sarkander
|c. 1220
Křižanov, Moravia
Lemberk Castle, Bohemia
|Venerated in
|Roman Catholic Church
|28 August 1907 by Pope Pius X
|21 May 1995, Olomouc, Czech Republic by Pope John Paul II
|January 1
|Depicted as a Dominican tertiary with a crucifix wound around with roses; lying in the place of a sick person in bed
|Difficult marriages; people ridiculed for their piety
Zdislava Berka (also, Zdislava of Lemberk; c. 1220 – 1252) was the wife of Havel of Markvartice, Duke of Lemberk, and is a Czech saint of the Roman Catholic Church. She was a particularly austere and generous woman who founded a convent.
Zdislava was from a Moravian family, born in Křižanov, in what is now the Žďár nad Sázavou District of the Czech Republic. She was reportedly an unusually devout child, who at age seven ran away into the forest with the intention of living a hermit's life of prayer and solitude. She was forcibly returned by her family, and made to live a normal childhood from that point on. Later, her family arranged for her to marry Havel of Markvartice (also known as Gallus of Lämberg or Havel of Lemberk) of the prosperous Markwartiner family. He founded the towns of Gabel (Deutsch Gabel) and Habelschwerdt. Together they would have four children.
As a married woman, Zdislava continued to live a life of remarkable personal austerity, worked tirelessly in the care of the poor and dispossessed, and was, unusually for her era, a frequent recipient of the Eucharist. Tatar invasions of Eastern Europe were causing large numbers of people to leave their homes during this period, and a large number of refugees sought refuge at the castle of Gable, where Zdislava lived with her family and assisted these refugees as much as possible.
Her husband was concerned about what he considered the excessive degree of Zdislava's charity to these refugees. In one incident, he is reported to have gone to the bed Zdislava had given to a feverish beggar the night before, but to have found a figure of the crucified Jesus there instead. He is said to have been so impressed by this apparition that he would later allow her to found a Dominican convent in Turnov. Zdislava worked with this convent for the rest of her life, and was eventually buried there.
Shortly after her death Zdislava is reported to have appeared in an apparition to her husband. In 1907, Pope Pius X confirmed her veneration for her native country. She was canonized a saint in 1995 with John Sarkander in a ceremony in Olomouc, Czech Republic, by Pope John Paul II. In artwork, she is commonly depicted as a Dominican tertiary with a crucifix wound around with roses, or lying in the place of a sick person in bed. As a patron saint, she is asked for her intercession in difficult marriages and for people ridiculed for their piety.
- Burns, Paul (1995). Butler's Lives of the Saints: New Full Edition. Collegeville, MN: The Liturgical Press. ISBN 0-8146-2377-8.
- Dolistová, Marie (2009). Paní Zdislava z Lemberka (in Czech, Polish, Upper Sorbian, German, Esperanto, and English). Prague: ŘÁD. ISBN 978-80-86673-15-8.


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The APNGOs Association will convene an all-party meeting here on December 20 to chalk out a strategy in support of Samaikhyandhra.
Association president P. Ashok Babu said that they had invited political representatives of Congress, Telugu Desam, Left parties, MIM, Lok Satta for the all-party meeting.
They could not meet YSR Congress president as he was not available, he told reporters here on Tuesday.
Mr. Ashok Babu said now that the bifurcation bill was introduced in the legislature, political leaders supporting united State would have to play a greater role as ultimately they were answerable to the people. It was time for them to prove their commitment to the cause of united AP and meet people's aspirations.
"As employees, our role is limited now but employees and people will extend their full support to the legislators against the Centre's unilateral decision to divide the State,"he said. Mr. Ashok Babu said that the APNGOs and other employees associations would continue their movement along with political leaders. Welcoming the debate in the Assembly and the Council, he said if there was no debate, how the members could express their opinion as directed by the President.Chalo Assembly
As the present session would sit for only two more days, the APNGOS and other employees associations will organise 'Chalo Assembly' against bifurcation during the special session when serious debate on Telangana Bill would take place, he said.
Keywords: APNGOs, Telangana, Andhra Pradesh bifurcation, Seemandhra, Telangana issue, Andhra Pradesh politics, Telangana Bill


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When Patti LaBelle, Gladys Knight and Fantasia Barrino take the stage during the Tony Awards ceremony Sunday night, they'll be there to showcase the new musical contender "After Midnight." But they won't be doing a number you'll see in the show.
Instead, they'll be performing in a new sequence that works the three guest stars -- who have appeared or will appear separately in the production -- into a full-cast mashup of two numbers from the musical. "It doesn't exist in the show," said director Warren Carlyle of the sequence. "It's a Tony special."
That kind of ongoing, freeform riffing seems in keeping with the spirit of the tuner itself, a jazzy take on a Cotton Club revue that reconfigures some of its production elements every time a new performer slips into the rotating guest-star slot. Each new star -- including kd lang, Vanessa Williams and Toni Braxton, in the wake of original guest artist Barrino -- has required new choreography, new costumes and, sometimes, new prop elements.
"It's like being a doctor on call," joked fashion designer Isabel Toledo, the show's Tony-nominated costume designer.
The improvisatory style of jazz great Duke Ellington -- whose years at the Cotton Club provide the inspiration for the show -- seems to have guided "After Midnight" from the start. According to Jack Viertel, the City Center Encores! a.d. who conceived "After Midnight," the musical began life as an amorphous idea for a project that would launch the new partnership between the nonprofit Encores! program and Jazz at Lincoln Center.
Wynton Marsalis, whose Jazz at Lincoln Center All Stars appear on Broadway as the production's onstage orchestra, pushed for an Ellington theme, and the piece grew out of the 80 or so pieces of music he brought to the table. From the common themes in those tunes emerged the concept for a musical with the feeling of a floorshow, but with enough of a loose narrative to carry the audience on a journey from birth to death, and from innocence to experience.
With Carlyle ("Hugh Jackman, Back on Broadway") on board as director-choreographer, the creatives went in search of performers with unique skills. Casting director Laura Stanczyk spent nine months drumming up an array of talent from TV stars (Dule Hill) to modern dancers (Karine Plantadit) to tappers (Dormeshia Sumbry-Edwards) to a memorable pair of hip-hoppers (Julius "iGlide" Chisolm and Virgil "Lil O" Gadson).
Then the creative team allowed the performers' individual talents to dictate the shape of several numbers. For instance, a tribute to Earl "Snakehips" Tucker evolved into a showcase for the differing -- and very contemporary -- styles of Chisolm and Gadson. "I was picturing a straight-up imitation of Snakehips," Viertel recalled. "But then we realized: What they're doing is the modern-day equivalent. It's is the great-grandchild of Snakehips."
The show's utopian vision of the Cotton Club through a contemporary lens won raves in its initial nonprofit iteration (then called "The Cotton Club Parade") at City Center in 2011, and again when the musical returned for a second limited run in 2012. For all that success, however, the commercial transfer was another improvisation, when producer Scott Sanders added guest stars to the mix, combining the model of an ongoing Broadway musical with that of a limited-engagement concert run.
The Main Stem transfer proved as well-received as the early incarnations, making "After Midnight" (along with another fall opener, "A Gentleman's Guide to Love and Murder") one of best reviewed new musicals of the season. Awards love followed, with the tuner racking up seven Tony noms in total.
Despite all the critical praise, box office has proven relatively soft since the show opened Nov. 3. Guest stars haven't quite brought the expected B.O. spikes, with the two-week stint of Braxton and Babyface Edmonds, who filled houses to about 90% of capacity, spurring the most obvious rush at the box office.
Pundits may consider chances to be slim for a revue like "After Midnight" to score the new musical trophy, but until the awards are handed out Sunday night, Sanders and company are capitalizing on the month-long window when the show can trumpet its status as one of four nominees for best new musical. Thursday afternoon saw the renaming of West 47th Street to Duke Ellington Way (pictured, above), just down the block from where "After Midnight" is playing. On Sunday, the appearance of LaBelle and Knight on the nationally televised Tony telecast is expected to help sustain the sales jolt prompted by recent news of the show's summer guest stars -- LaBelle, Knight and Natalie Cole.
Before then, of course, Toledo still has to finish LaBelle and Knight's costumes, and Carlyle must polish up the Tony number's choreography. But none of that will pose a problem. At "After Midnight," they're used to improvising.
Related storiesBroadway Play 'All the Way,' Starring Bryan Cranston, Recoups Its $3.9 MillionJennifer Hudson to Perform a Song from 'Finding Neverland' at the Tony AwardsRoad to the Tonys: The Golden Links With Oscar and Emmy 2014 Variety Media, LLC, a subsidiary of Penske Business Media; Distributed by Tribune Content Agency, LLCCopyright © 2015, The Baltimore Sun


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Targeted Oncology Biomarker Solutions in the Elucidation of Inflammatory Breast Cancer Mechanisms, Webinar Hosted by Xtalks
Part 2 in this Genomic Series will help cancer researchers better understand how genomic data can be used to gain insights into drug resistance, and will focus specifically on resistance and response in a specific subtype of breast cancer. The live broadcast takes place on Wednesday, May 28, 2014 at 1 p.m. EDT.
Toronto, Canada (PRWEB) May 09, 2014
Next generation sequencing (NGS) has posed new challenges and opportunities in cancer treatment and drug development. NGS has allowed clinicians and researchers to identify variants in cancer that may be predictive of response and resistance to oncology drugs. However, NGS outputs are typically large & complex datasets that are often difficult to interpret.
The speakers, Dr. Sarah Bacus, Senior VP and Chief Scientific Officer, Translational R&D Oncology, Quintiles, and Jeff Fitzgerald, Director, Personalized Medicine Integration, EA | Quintiles, will describe:
- The analysis of NGS data generated using a targeted cancer sequencing panel from a multi-sample cohort of patients
- How this data has led to new insights into drug resistance and response in a specific breast cancer subtype
Particular emphasis will be placed on contextualization of variants with respect to biological pathways.
By attending this webinar, the audience can expect to gain insights into translational approaches that may be used to understand the biological implications of genomic variants and their interaction with drug response.
This webinar is part of a 5-part series on Genomics Know-How®. To register for this session or learn more about the series visit: Genomic-Know-How.
Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global Life Sciences community. Every year thousands of industry practitioners (from pharmaceutical & biotech companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.
To learn more about Xtalks visit http://xtalks.com.
For information about hosting a webinar, visit http://xtalks.com/sponsorship.ashx.
Michelle Tran
Tel: +1 (416) 977-6555 ext 284
Email: mtran(at)xtalks(dot)com
For the original version on PRWeb visit: http://www.prweb.com/releases/2014/05/prweb11837826.htm


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Olympic gold medalist Dominique Dawes has love for the newest African-American gymnast representing Team USA, but she's not feelin' her nickname.
Gabby Douglas, 16, the only Black member of this year's Olympic women's gymnastics team, has Dominique's support, but the '96 Olympian refuses to refer to her as "The Flying Squirrel."
"I'll be honest with you. I do not like that nickname. I'm going to call her 'Doin' It Douglas,' 'Wowing It Douglas.' I am trying my hardest to come up with a nickname that's going to stick," said Dominique who didn't explain why she dislikes the name.
"She does fly on the uneven bars. She wows the crowd. You jump out of your seat. Maybe you can be creative and come up with a good nickname," Dominique said.
The young gymnast wowed audiences in London, and advanced farther than many had expected. She is a serious threat to win an gold in the all-around competition. If she earns gold, Gabby will be the second African American to hold the honor.
Although names and medals are important when it comes to the Olympic games, Gabby's family will celebrate no matter the outcome.
"I told her we're gonna celebrate when you win a gold medal like you won a gold medal. You win a silver medal, we're gonna celebrate like you won a gold. You get a bronze, again, we're celebrating like you took home the gold. You don't get a medal at all, we're going to be there partying like there's no tomorrow," Gabby's mother Natalie Hawkins said.
"We're going to have a party no matter what you do. Forever more you're an Olympian and that says it all."
Watch a video chronicling Gabby's journey below.
—Tracy L. Scott
Are you watching Gabby compete? Do you like her nickname? Does it matter one way or the other? Leave your comments below.


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Colombia Cerro Azul Enano
Colombia Cerro Azul Enano
Introducing the new crop arrival of Cerro Azul Enano, an ongoing exclusive offering at Equator. As many of you know, Cerro Azul is a coffee farm owned and operated by our quality-obsessed friends at Granja La Esperanza. The farm was planted exclusively to the rare and celebrated botanical variety known as Gesha (or Geisha), or so they thought. As the coffee trees began to mature, it became evident that a small number of trees did not look like Gesha. The compact size of the trees and the dense foliage were distinctly different than the taller, rather sparse Gesha bushes. No one was sure what the true identity of this dwarf variety is. As such, the plants were dubbed Enano, which means dwarf in Spanish.
Because it was not thought to be of the Gesha variety, Granja La Esperanza began processing the Enano cherry separately. When we tasted in Colombia a few years ago we offered to purchase the entire production of this Gesha-like coffee. Whatever the actual variety, the intense floral tones is clearly reminiscent of the Gesha type. Our understanding of this coffee is evolving over time. Originally we thought it might just be a great tasting Arabica species coffee, the shrub looked a little like the Catuai variety. Now we are beginning to think that it is an actual dwarf mutation of Gesha. As the plants continue to naturalize on the farm it seems as if the Gesha-like characteristics are becoming even more intense.
Cupping Notes
Delicate aromas of gardenia and jasmine combine with flavors of milk chocolate, strawberry preserves and sweet table grapes.
View map of the growing region for Colombia Cerro Azul Enano
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2 HOURS AGO - People
A Must Read - Share
The 19 Kids and Counting star admitted to molesting underage girls as a teen
6 HOURS AGO - Perez Hilton
This sounds pretty reasonable.
Last year, TLC canceled Here Comes Honey Boo Boo after Mama June was spotted with her horrible ex-boyfriend and child molester Mark McDaniel.
Well, the network still hasn't officially cancelled 19 Kids And Counting despite the recent admissions of Josh Duggar being a child molester.
[ Related: 19 Kids ...
MAY 22, 2015 - Reality TV Magazine
Unfortunately for Britt Nilsson, Kaitlyn Bristowe is the more popular of this season's two Bachelorettes. Britt's a nice gal, but there just something about Kaityn that makes us want to see more. Chris Soules evidently agrees with the guys fighting for the roses, as well as the dedicated members of the Bachelor Nation on Facebook. […]
MAY 22, 2015 - Business Insider
Bill Murray may be more myth than man at this point. He has been known to crash random events, such as bachelor parties. Dozens of stories have been shared online, and many of them sound almost too good to be true. Now, Murray will be getting his own Netflix Christmas special, simply titled "A Very Murray Christmas." "A Very Murray ...
6 MINS AGO - Hollywood Life
The very private Kanye is definitely planning a special surprise for Kim to celebrate their one-year wedding anniversary.
2 HOURS AGO - Hollywood Life
Kim and Kanye's first dance as a married couple was just as perfect as we'd imagined.
MAY 23, 2015 - Just Jared
George Clooney, Britt Robertson, and Hugh Laurie pose for a pic together while making an appearance on The Graham Norton Show on Wednesday (May 20)! During the show, George, 54, chatted about playing pranks on close friend Brad Pitt. "I'm not sure how it started but we have done some terrible things to each other. [...]
Get ready to run from crazed zombies with Brad Pitt again. Paramount has announced that the sequel to its 2013 thriller "World War Z" will be released June 9, 2017, according to Variety's Dave McNary. Pitt will again star and produce the film. The first movie, based on the popular Max Brooks novel, revolved around a United National employee Gerry Lane (Pitt) ...
MAY 22, 2015 - Seattle Times
Barry Manilow says this is his last big tour. The soft-rock master performs at KeyArena on Wednesday, May 27.
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