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|Avanir Pharmaceuticals Announces Presentation of Positive Early Results from PRISM II Study
"These initial data showing reduced symptoms of pseudobulbar affect (PBA) in patients with PBA secondary to Alzheimer's and dementia are consistent with the benefits we saw in the pivotal phase III study, in PBA patients with ALS and MS, and provide further evidence that NUEDEXTA may offer relief from the debilitating episodes of PBA," said
"PBA can have a devastating impact on the lives of patients that are already suffering with neurologic disorders such as Alzheimer's disease and other dementias," said Stephen D'Amico, MD, CMD, medical director at
PRISM II assessed the safety and efficacy of NUEDEXTA in treating PBA in patients with Alzheimer's disease/dementia, stroke and TBI. While the Alzheimer's disease/dementia cohort is now fully enrolled at 134 patients, at the time of interim analysis 96 patients had evaluable safety data and 68 had effectiveness data (at least 30 treatment days). The study endpoints included a PBA symptom rating (
About PRISM II
PRISM II is a nationwide, open-label, multicenter, 12-week study enrolling up to approximately 450 patients at approximately 100 study centers. Eligible patients are aged >18 years with a clinical diagnosis of PBA and baseline score >13 on the
Poster Presentation Details:
Poster Number: 45758
Presentation Time:
About PBA
The CNS-LS has been validated in ALS and MS patients.
About NUEDEXTA
NUEDEXTA Important Safety Information
Studies to support the effectiveness of NUEDEXTA were performed in patients with amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS). NUEDEXTA has not been shown to be safe and effective in other types of emotional lability that can commonly occur, for example, in Alzheimer's disease and other dementias.
NUEDEXTA and certain other medicines can interact, causing serious side effects. If you take certain drugs or have certain heart problems, NUEDEXTA may not be right for you.
NUEDEXTA causes dose-dependent QTc prolongation. When initiating NUEDEXTA in patients at risk for QT prolongation and torsades de pointes, electrocardiographic (ECG) evaluation should be conducted at baseline and 3-4 hours after the first dose.
The most common adverse reactions are diarrhea, dizziness, cough, vomiting, asthenia, peripheral edema, urinary tract infection, influenza, increased gamma-glutamyltransferase, and flatulence. NUEDEXTA may cause dizziness.
These are not all the risks from use of NUEDEXTA. Please refer to full Prescribing Information at www.NUEDEXTA.com.
Avanir® and NUEDEXTA® are registered trademarks owned by
Forward Looking Statements
Avanir Investor & Media Contact
Brewlife Media Contact
Logo - http://photos.prnewswire.com/prnh/20130207/LA55901LOGO


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Arab Heat - Scene 4
Bruno Bond gets Damien Crosse's cock all wet, sucking slowly and deeply in this video. He then lifts Crosse's legs, and stabs his tongue deep inside the hairy hole, making him moan for more. After Crosse has been serviced, he takes charge by mounting Bond from behind, and sticking his thick cock, deep inside Bond's hairy ass. Bond's face shows a mixture of ***** with immense pleasure, as Crosse rides his ass wildly.
Website: CLICK HERE
Added: 27 Nov 10
Views: 60233
hunk / big muscles

subset: commoncrawl


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Seattle CB Browner out for 2nd straight game
Seattle Seahawks starting cornerback Brandon Browner is inactive for the second straight game with a hamstring injury.
Browner was ruled out of Sunday night's NFC West showdown with San Francisco. He was hurt in practice last week and missed the season opener at Carolina. He was listed as doubtful on the final injury report.
Seattle is also without defensive end Chris Clemons as he recovers from offseason knee surgery, but Cliff Avril is active after missing last week's opener. Avril is expected to start at defensive end.
San Francisco is healthy with the exception of backup running back and kick returner LaMichael James, who's out with a knee injury. James was questionable on the final injury report and missed last week's opener.
AP NFL website: www.pro32.ap.org
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NFL Headlines
NFL Insiders: Dolphins name Dennis Hickey new general manager
Carroll: Seahawks CB Richard Sherman sorry about postgame rant
Browns to interview Bills' Pettine with Broncos' Gase out of running
NFL talking to 49ers about sideline hit vs Seahawks in NFC title game
Falcons hire former Chiefs GM Pioli as assistant general manager


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Sox' newfound resiliency refreshing
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- Boston Red Sox
ANAHEIM, Calif. — We don't mean to pick on Adrian Gonzalez, because he was far from last year's only problem.
But Gonzalez is a good place to start when one ponders why the 2013 Red Sox are so much more resilient than their predecessors.
Last May, the Red Sox dropped a 2-1 contest to the Rays at Tampa Bay. Gonzalez went 0-for-4 and struck out twice. After the game, he blasted the umpires.
"I do have a question," Gonzalez said. "How are you supposed to have a professional at-bat with these umpires nowadays? Gosh."
He proceeded to complain, in extensive detail, about the first pitch of his at-bat in the eighth. He also expressed displeasure over multiple called strikes from earlier that week against the Mariners.
Gonzalez was the highest-paid player on the team, and the second-highest-paid player in Red Sox history. He was the central superstar on a club built around them. And even if his complaints were justified, it didn't change that he was setting a whiny tone.
Fast-forward a year. The 2013 Red Sox have the most wins in baseball and have handled tough defeats as well as any team, the latest coming when they blew a 7-3 lead in the ninth Saturday in a 9-7 loss in 11 innings to the Angels.
Last night's slightly more routine 3-0 setback against Los Angeles not withstanding, the question is why they are able to overcome what last year's team could not.
"You saw it last year, every time we lost a game: 'Oh man, the umpire, if he would've made this call, we would've done this,' " catcher Jarrod Saltalamacchia said, without singling out Gonzalez. "Well, enough's enough. We can't sit there and complain and bitch and moan about someone else. It's about, 'What did we do? How do we make this team better?' "
That was certainly the approach a couple of weeks ago in Detroit after the Red Sox lost 3-of-4, but just as easily could have won 3-of-4. The crusher came in the series opener, when closer Andrew Bailey allowed a walkoff, two-run homer to Jhonny Peralta.
The finale against the Tigers, a 7-5 loss, featured a fielding blunder by first baseman Mike Napoli, who had a chance to record an unorthodox double play, but tagged the bag before the runner, thus eliminating the force. Afterward, Napoli looked pretty hangdog at his locker, at least until spark plug and leader Dustin Pedroia started joking with him for teammates and media to see.
"I was just yelling at Nap to tag everybody," the second baseman said. "Nap, did you tag the first base coach?"
It was just a little thing, but as the players filed out of the clubhouse for the flight home, they didn't look particularly defeated. And how did they respond? By winning nine of their next 10.
"Most teams with an inability to turn the page think about what they should have done differently as opposed to what they need to do tomorrow," noted left-handed reliever Craig Breslow, who took the loss Saturday. "We do a good job of understanding that yesterday's game is over and we need to win today, and not reliving what we should have done different so we would've won yesterday."
As an example of how this year's team operates, consider outfielder Jonny Gomes, particularly in light of the Gonzalez quotes above.
"Jonny, for instance, had a (seven)-game hitting streak," Saltalamacchia said. "He's raking. Then he's not in the lineup. Does he complain about it? No. He gets ready, and when it's his time to go, he goes."
That's part of being responsible to himself and his team, and not in that order.
"I knew in spring training we had a good team and personalities were starting to click," Saltalamacchia said. "I didn't think it would be like this, not the winning, but the team chemistry and the expectations of each other. We don't let anyone slip. We have responsibilities and we hold each other accountable, which is what you've got to do, and last year we didn't. We didn't hold each other accountable enough to get better. That's what we do well this year. We challenge each other to get better."
Needless to say, it is a welcome change. When these Red Sox lose, they don't blame the umpire. They go out the next day, or the next series, and find a way to win.


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Dave Stead
PODCAST PAGE: Veteran's Day 2014 The WCCO Morning News With Dave Lee
A snowy Tuesday on the MORNING NEWS WITH DAVE LEE. Click the link above to listen back via Dave's PODCAST PAGE!
Minnesota Bans 'Piggyback Bandit' From Prep Events
Minnesota is banning the man known as the "Piggyback Bandit" from high school games in the state.


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For sale in our Orlando showroom is a 1966 Buick Riviera. This gorgeous matte black Riviera is certainly a sight to behold and one... More
Motorcar Studio is pleased to offer this 1966 Buick Riviera GS finished in Riviera Gold Poly (paint code G) over black interior. The car... More
BUICK: 1966 Riviera, 350 TPI engine, very dependable, $9,500. 805-300-7825, CA; email for photos: [email]... More
BUICK: 1966 Riviera, complete solid body, nice bumpers and trim, restore or part it out for only $3,495 obo. 405-392-3447, OK; www.okoldies.com**35-YR**... More


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Twelve area high school seniors were recently honored before family and as graduating members of the New Vision Program, Class of 2014. The heartfelt ceremony capped a year of rigorous academic work paired with clinical rotations alongside Adirondack Health staff.
In a room filled to capacity, opening remarks were made by Adirondack Health Chief Nursing Officer Linda McClarigan and Program Director Alison Riley-Clark followed by the presentation of graduation certificates to students. New Vision is a division of the Adirondack Educational Center and the Board of Cooperative Educational Services of Franklin, Essex and Hamilton Counties (BOCES).
This year's graduating class included: Hanna Potter (Lake Placid), Lindsay Yamrick (Tupper Lake), Cassitty Rose (Saranac Lake), Aaron Noel (SL), Gwen Goudreau (SL), Krystal Gilbert (TL), Hanna Courcelle (SL), Janelle Edwards (TL), Jenny Ward (SL), Brittany Woodruff (SL), McKayla Duffy (SL) and Ranya Hamdan (Long Lake).
Kathy Craft, of the Saranac Lake Voluntary Health Association (SLVHA), presented $1,000 scholarships to Hanna Potter, McKayla Duffy, Cassitty Rose, Jenny Ward, Brittany Woodruff, Lindsay Yamrick and Ranya Hamdan. Hannah Hanford, Executive Director of the Adirondack Health Foundation, presented a $3,500 scholarship to graduate Janelle Edwards of Tupper Lake. Dr. David Welch, a physician with Adirondack Internal Medicine and Pediatrics, provided the closing remarks to the graduates, reminding them to be sure to make time for friends, family and simple joys in their busy lives.


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- Shopping Bag ( 0 items )
This expansive and carefully crafted reader brings together many of the classic texts that help to define culture as a tool of resistance. With concise, illuminating introductions throughout, it presents a range of theoretical and historical writings that have influenced contemporary debate, and includes a number of new activist authors published here for the first time.
Cultural Resistance Reader is both an invaluable scholarly resource and a tool for political activists. But most importantly it will inspire everyday readers to resist.


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Supply Chain
Samsung finds child labor in supply chain
The South Korean electronics giant has learned of allegations that one of its Chinese suppliers uses child labor.
Viewing IP as a supply chain
Companies that review, assess and optimize at their entire IP supply chain can gain significant competitive advantage and enhance corporate value because they can put into place action plans to address any delays or inefficiencies found in their current process.
List released of 100 top supply chain projects
Big Data has most recently come to impact the supply chain as more points of data become available and supply chain managers use big data analytics to better pin the pain points of the supply chain. Digital analysis is just one of the ways in which the supply chain is...
Foxconn's compensation debate highlights Taiwan's wage problems
Foxconn has been in the international spotlight for a few notorious reasons — one being its rash of employee suicides over the last couple of years. Its association with Apple device manufacturing has put it front and center in the human rights arena. But a recent debacle dubbed the "Liang...
The state of supply chain in 2014
Today, delivering more products faster, with flawless execution and minimal business interruption defines supply chain success. Closing loops, redefining boundaries, and keeping simple principles in mind are all hot supply chain topics.
SEC receives first conflict minerals report
The first report has been submitted by Siliconware Precision Industries in the form of a filed Form SD — the new report through which companies must file their conflict mineral reports by June 2.
Big data can have big impact on supply chain management
The use of data analytics is underused in supply chain management to minimize risk exposure.
The role of business in preventing modern-day slavery
International laws and rules to address human trafficking have been in place for decades, but new efforts are being made around the world to confront this terrible issue.
SEC releases new guidelines governing conflict mineral disclosure
These new questions and answers deal heavily with independent private sector audits (IPSA) of an issuer's Conflict Minerals Report and the scope of disclosure within a company's reports.
EU drafts conflict mineral compliance regulation
Compliance regulations for companies that handle conflict minerals have been revamped over the last few years as awareness regarding the human rights violations come to light.


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Volkswagen demonstrates fully-automatic reverse parking system
The system has been demonstrated in a Volkswagen Passat Variant
Parking without driver at the Hannover Messe 2008
Prof. Dr. Jürgen Leohold, Executive Director Group Research Volkswagen AG
Volkswagen's Park Assist Vision system
Minor collisions as a result of parking mishaps are a common, costly and extremely frustrating occurrence and for several years auto manufacturers including BMW have indicated that solutions that take human error out of the equation are on the way. The latest news in the area comes from Volkswagen, which has demonstrated its "Park Assist Vision" system at this year's Hanover Fair. The fully-automatic, remotely-operated self-parking system lets you get out of the car and watch as it backs itself into even the skinniest of perpendicular spaces, using cameras located in the left and right exterior mirrors to gauge the dimensions of the parking area available and communicate this information to the computerized steering and drive systems.
« Back to Volkswagen demonstrates fully-automatic reverse parking system
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District on 119 Apartments605 SW 119th St., Moore, OK 73170 View On Map (405) 652-0872
Brand New Apartment Community with onsite storm shelter!
Located near 119th and South Western, the brand new District on 119 is now leasing! Our one, two and three bedroom apartment homes have a variety of sought after amenities including garden tubs, brushed nickel accents, over sized closets, patio/balcony, and hardwood floors plus so much more! With a full size washer and dryer included, the tasks of everyday life are more convenient and enjoyable. The kitchen is stylishly equipped with modern black appliances including microwave, dishwasher and refrigerator with ice maker. The open floor plans create a flexible layout with a cozy feel. Last but certainly not least, our residents will find added comfort during severe weather threats by utilizing our community storm shelter! Your peace of mind is our priority!
District On 119 is located in the Oklahoma City Area in the 73170 zip code. View this apartment on a map.
Pricing & Floor Plans
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|Price Range
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Office Hours
- Monday - Friday, 9 AM-6PM
- Saturday, 10AM-5PM
- Sunday, 12PM-5PM
Why You'll Love Us
While there is much to love about the conveniences of living near 119th and South Western in Oklahoma City, what lies within the controlled access gates of District on 119 will have you hurrying home to enjoy life! Hard day at work? We have just the cure, whether it's sweating out the frustration in our state of the art fitness center, or relaxing in your garden tub surrounded by bubbles and soft music. Ready for some fun times with friends? You have options at District on 119...enjoy the community tv lounge indoors, or the resort style pool and lounging area outdoors. Call or come by to discover what your favorite part of coming home to District on 119 will be!
Features & Amenities
- Brand New!
- Fitness/Health Center
- On-site Management
- Brushed Nickel Accents & Lighting
- Modern Black Appliances
- Roommate Friendly Floor plans
- 4 Story Buildings with Elevators
- Resort Style Swimming Pool and Lounge Area
- On-site Maintenance
- Hardwood Floors
- Cable Ready
- Storm Shelter
- Community Lounge with Free Internet Access
- Package Receiving
- 9' Ceilings
- Large Garden Tubs
- Garage Available
Floor Plan Features & Amenities
- Controlled Access Gates
- Full Size Washer/Dryer in Unit
- Balcony
- Furnished Apartments Available
- Microwave
- Patio
- Ample Closet Space
- Refrigerator w/Icemaker
Maps & Directions
About Us
Professionally Managed By: SC Bodner
Also visit us here: Visit this Property's Website, Like us on Facebook
Pet Policies
Dog: Up to 2 are permitted
- 2 Pets maximum per apartment. $200 Fee is non-refundable. Up to $200 of deposit is refundable.
- Restrictions: ask your leasing professional about weight and breed restrictions.
- Size: Small
- Deposit: $200.00 Rent: $20.00 Fee: $200.00
Cat: Up to 2 are permitted
- 2 Pets maximum per apartment. $200 Fee is non-refundable. Up to $200 of deposit is refundable.
- Size: Small
- Deposit: $200.00 Rent: $20.00 Fee: $200.00


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Get your pizza on our menu
We're inviting you to create your own pizza to feature on our Autumn menu. Not only that but you will also be entered into our draw to win £10,000 and a holiday for two.
The New Spring Menu 2015
A fresh take on old favourites with the Romana 65s and more fresh flavours to try.
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