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Michael Jackson: Dangerous
Regardless of what Michael has done to himself over the years there's no doubt the dude can sing and dance. This cover for Dangerous is one of my favs and was also submitted by Elias of A+.
Designed and painted by Mark Ryden, again of Juxtapoz fame. It's one that would have looked glorious as a 12 inch sleeve. You can look at this for hours and not see everything reviled only by Sgt. Peppers Lonely Hearts Club as one of the most intricate covers.
They released a special edition (before the word collectors had become popular) that folded out to become a diorama.
The closed cover was a masked version of the cover (see below)
This was well before Michael's obsession with masks.
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65 Comments
the amount of detail and reference to the lyrics contained within and the mythology around Jackson is so intricate in this cover it could take many hours to decode and get it al. One of the better album covers of the 90s in terms of artwork.
[...] actually had this one waaaay back in the day. I'm not ashamed. That shit was fire. [...]
Yea, that Michael Jackson was dangerous…
I actually have a copy of the special edition CD cover – really cool, intricate design.
I really love this album cover. I strive to create something this epic!
I love it!
sera q s siorama esta en algun museo (para robarlo)jajajajajajaj s broma
This was a fantastic piece of art. Ryden has gone on to become even more famous… and has grown a strange obsession with Christina Ricci and raw meat (?)… but this one always stands out.
this album art work is very creative.
the ammount of detail that went into its design is incredible. It shows what i think michael loves, and shows items in his life.
good work on the art1!!
NO Matter whats is happening in his personal life, He and all that related to him are all unique and creative.
It's a great cover indeed. I didn't know it was Ryden's work. By the way, it's heavily influnced by Bosch's paintings. Or maybe the right word would be "a rip-off" of Bosch's paintings.
I had this as a 12″ as a kid, and spent hours poring over all the details. Love it.
He had the eyes as a logo for a while. Places where you would've expected to see a label reading "MICHAEL JACKSON" just had the eyes.
And no, it's not very similar to Bosch's work at all, Luca. Other people have done big pieces with lots of details too.
I love this picture.
Beautiful cd-art, my favorite. See this, it´s amazing: http://www.lacortedelreydelpop.com/artedetapa4.htm
This is propagana brainwashing. Look at you all lap it up!
Michael Jackson is hailed today as the King of Pop. On the cover of the recent "Dangerous" Album, the freemasonic symbol of the one eye can be found as well as a picture of a bald headed man well known to the Occult (Satanists) as Alistair Crowley. Alistair Crowley himself was a freemason who became a Satanist and wrote the book "The New Law of Man", which stated in it that it would one day replace the Quran as the law of man.
Beware the new world order! Actually pay attnetion to what you are reading, watching and listening to.
I thought it was great, but then again all of his album are!!! I hope that you michael will get out of this mess. and to all the fans out there in the world, WE GOT TO HELP HIM IN ANYWAY WE CAN!!!
to david:
how come you think that's Alistair Crowley on the cover…?
This CD was actually issued on vinyl. It is indeed wonderful to look at when the media is larger than a CD booklet.
es lo mejor michAel jackson
Damn , michael dangerous album cover is so hot.
Michael jackson has always had a unique taste, from his music to dance and life style, his is one in a billion. This album art is no exception… Ryden is totally awesome. Long live the King… Long live Michael Jackson.
I was fortunate enough to had been working at Tower Records at the time Dangerous was released in November of 1991. I have a 36X36 promo poster of this cover. It is truly something to behold at that size. I have been a huge Michael fan since 1969. I really think Dangerous is his best solo work to this day. Not one bad cut to be found here. He obviously did stellar work with Quincy Jones but a change was needed.
hi i love michael muics
Michael Jackson id death… now.. his in neverland…. RIP my hero…
God bless you Michael, May you rest in peace. I Love You.
o mundo acaba de perde um grade homem e um maravilhoso conto,pra mim ele sempre estarar em nossos coraçoes,eu agora so espero q ele fike bem onde quer que ele estege,michael foi um homem maravilhoso
e um belo canto ñ dar para escrever aqui tudo o q ele é mais ele é realmente incrivel.michael vc é tudo de bom sempre vc vai ser lembrado em nossos coraçoes!!!!!!!!!!!!
David (see post above) may be a seriously deluded and paranoid soul, or maybe just a know it all type who spouts off without any factual basis for his statements. What are you lapping up dude? Whatever his reasons the figure he identifies as Alister Crowley is a depiction of Phineas T. Barnum of P. T. Barnum's Grand Traveling Museum, Menagerie, Caravan & Hippodrome fame, he is the "Barnum" in the Ringling Brothers Barnum and Bailey Circus, you know the greatest show on earth? The Circus? Ring any bells? and the figure on PT's head is likely Charles s. Stratton AKA General Tom Thumb a performer who worked for Barnum. To be fair to our paranoid friend Charles Strantton was reported to be a Freemason. On a final Note the association of occultism as Satanism is a misleading one. While Satanists and Freemason may be branded as occultists by some few Christian religious folks the simple fact of the matter is the term is often used to describe Catholics and could just as easily and accurately be used to describe any supernatural belief system including the Christian belief system. The word occult is most accurately used to describe "hidden knowledge" but a peak behind the curtain reveals it is mostly used to describe secret nonsense masquerading as knowledge such as the beliefs shared by Satanists, Christians and other theists. To try and associate the word solely satanists with the word is disingenuous at best. also Alister Crowley is known to may people not just Satanists, and I believe that to describe Crowley as a satanist is disinformation that may indicate your having a hidden agenda, could our dear David be an occultist? would the real slim shady please stand up!
And as for my 2 cents Mark Ryden is a great artist in my book, personally I enjoy his work much more that that of the late Michael Jackson.
michael jackson sos el mejor cantante del mundo siempre te recordaremos ojala ya estes con dios para que te proteja te queremos argentina
This is propagana brainwashing. Look at you all lap it up!
Michael Jackson is hailed today as the King of Pop. On the cover of the recent "Dangerous†Album, the freemasonic symbol of the one eye can be found as well as a picture of a bald headed man well known to the Occult (Satanists) as Alistair Crowley. Alistair Crowley himself was a freemason who became a Satanist and wrote the book "The New Law of Manâ€, which stated in it that it would one day replace the Quran as the law of man.
Beware the new world order! Actually pay attnetion to what you are reading, watching and listening to.
# 15 Jul 08 at 1:03 pm'
couldt have put it better myself.
however, i dont think MJ had much of choice as to what exactly was put on this cover or as well as symblical meaning behind each one of the cleverly hidden beliefs portrayed in this cover.
this is infact a low blow placed by the artist who had done this piece of work.
to portray his own agenda through the name of a famous world known singer.
in this case it was MJ.
its the same corrupt system thats is and has taken over more then half the world.
for those of you readers who dont know what we are blabbing on about, i suggest you swallow your ignorance and open your eyes to see what is actualy taking over and running your lives.
^^ he lives no longer
i loved michael so much and i am so sad to see him go. He was a legend and i dont care what bad things people say about him because he rocks,! Rip michael 1958-2009 xxx
lo mejor michael jackson se te extraña muxo te amo y love you…………………!!!!!
Michael is true legend. King of Pop..A great person. When I saw his biography on Nat Geo. My heart felt great respect to this great man. He as single, lonely, talented, fun person. Fond of Children. Those allegations against him are baseless. I love Mike for his lifestyle, great dedication and an awesome guy, show stopper. God bless his soul. May his soul rest in peace.
Michael jac
ola michael yo se q tu no escullas pero desidi mandandote mensaje
ola michael yo se q tu no me escuyas asi te mando muchos besitos y descansa en paz michael tu querias morir
michael mi amiga dijo porque moriste tu porq no muestra la cara de tus hijos chao de rosemery
hay i love mj very much.can give me
This is one of my favorite album covers. It's right up there with Earth, Wind & Fire's "All n All", The Beatles "Revolver" and "Sgt Pepper" album covers. I love album covers like this. It makes the music that much more "colorful" when you listen to the album.
interesting that people in this topic actually go beyond the aesthetics & into the way culture is permeated with actual teaching. It's not like you should compare the symbolic saturation of MJ's communication on this album with a church sermon; church sermons teach while their audience knows it's being informed or even instructed.
With so much popular culture, it's like guidance is in the drinking water. We just gobble it up. I agree with david on that.
hello michael i love you miusic and you
wow,dangerous è fantastico già dalla copertina….è stupendo,amo michael
…..michael i love you….
you are not alone….
michael i love you and whoever runs you down i will track the down and get them.
i have a first edition first printing of dangerous diorama and am interested in selling it ,if interested get intouch
i'm so sorry.i will miss my brother very much i can't belive that my brother is death.my favorite tour was the dangerous tour and i will never forget him
i'm so sorry.i will miss my brother very much i can't belive that my brother is death.my favorite tour was the dangerous tour and i will never forget it
i love you michael jackson so mach you are the bast man in the world and you are not along am hear with you and you are in my hart for ever i love you
michael you are so genius song and you handsome love you michael jackson and you nare the best song and the best dance love you KING OF POP
i love u mj
i love u mj
I have this Album with the diorama is it worth anything ?
i like michael jackson the gold around his face he is the king of pop
te amoo mirey de reyes tii amoo
please inform of the price of the album Dangerous by Michael Jackson
Hhe article's content rich variety which make us move for our mood after reading this article. surprise, here you will find what you want! Recently, I found some wedsites which commodity is colorful of fashion. Such as mbt outlet store that worth you to see. Believe me these websites won't let you down.
I remember the day the album was released (Nov 1991) as I was speeding over to Musicland to get it. I got sucked into Ryden's storybook cover and have never come back out.
Dude you are!
I <3 mj!!!!!!!!!!!!!!!!!!!!!!!!!!!
he ix the king of music
wow //J
its cover with masonic signs…smh
its cover with masonic signs…smh
It's sad that still today most people including me did not know what the message was on this album artwork. The Dangerous album cover is filled to the brim with satanic symbolism. I think Mike was telling us about the dangers of poularity and hollywood. Since his death La Toya Jackson is telling a different story about how he was influenced through people to do things that he really didn't want to do. That artwork has the picture of Alister Crowley, the all seeing eye, Baphomet, skull & bones, naked child etc…
I miss you Michael know matter what nobody says


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Bullitt County youth who model a drug-free life will be recognized at a poster unveiling Wednesday, August 12, 2009 from 6:00-8:00 p.m. at the Shepherdsville Government Center, 634 Conestoga Parkway.
These VIP's will autograph copies of their poster for the public at the unveiling.
Nominated youths wrote an essay and were interviewed prior to the selection by a panel of community, civic and business leaders. Youth selected for posters exemplify a stand against harmful substances in their lives.
SHEPHERDSVILLE - It's not a shovel-ready project for federal stimulus money but it's close.
The Shepherdsville Police Department has been awarded a Community-Oriented Policing Services (COPS) grant for $183,859.
The funds were part of a $1.25 million program set aside for law enforcement agencies in the Second Congressional District of Kentucky.
U.S. Rep. Brett Guthrie announced Shepherdsville's grant on Tuesday. It is part of the U.S. Department of Justice's COPS Hiring Recovery Program.
BOWLING GREEN - Manager Scott Belt was confident that the bats of his Blue Lick 15-year-old All-Stars would come alive in the state baseball tournament.
And, for one inning, they did. Unfortunately, the offense didn't make the trip to Bowling Green and the local team finished with a 2-2 record.
In the opener, Blake Hardy pitched a complete game and Blue Lick won 4-0.
However, they did it without getting a hit off Warren County pitchers.
Combining errors and walks, Blue Lick advanced to a second round encounter against Henderson County.
LEBANON JUNCTION - A year ago, police chief Darrell Paul was removed from his position as police chief.
Now, the dismissal is a point of discussion for the Bullitt Circuit Court.
Attorneys representing Paul and the city of Lebanon Junction were recently in court with each asking Circuit Judge Rodney Burress to rule in favor of their summary judgment requests.
Kristie Walker, insurance attorney representing the city, said that Lebanon Junction mayor Butch Sweat removed Paul on July 30, 2008, at-will.
Bernheim Arboretum and Research Forest celebrated its 80th Anniversary July 12 with a community wide bash for the whole family.
Look for more photos inthe galleries of www.pioneernews.net.
BARDSTOWN - The O'Reilly Battle of the Bluegrass DirtCar Series presented by Graphic Impressions was in action on Saturday evening at Bluegrass Speedway for the 11th Annual Bluegrass 50 and Victor Lee of Stanford, KY would nip Terry English coming off turn four to the checkered flag to capture the $5,000 payday. Other feature winners included Pat Hagan of New Haven, KY in WBRT 1320-AM Sportsman and Jason Wheatley of Loretto, KY in Modifieds.
OKOLONA - It was a tough night all the way around for the Blue Lick 13-year-old All-Stars.
With the first game running long, Blue Lick and Prairie Village had to wait around an hour past the original 8 p.m. start time. And then they had to move from one field to another.
And at the end of the evening, there was even a little bad blood between the teams.
Prairie Village broke the game open with seven runs in the second inning en route to a 12-1 five-inning victory.
The victors did have 10 hits but also capitalized on five Blue Lick errors and four walks.
HILLVIEW - A common word in the sports world is 'rebuilding.'
For the Bullitt County Dolphins, the 2009 summer swim season will best be known for the word 'relocating.'
Student energy teams at seven Bullitt County Public Schools were recognized May 18 for promoting awareness and reducing energy consumption.
Overall since the district started implementing energy conservation efforts over two years ago, there has been a cost avoidance exceeding $250,000 in annual energy costs.
Bullitt East High School student earned the Overall Gold Award for their year end report and additional activities related to energy conservation.
District Energy Manager Andrea Rock lauded the efforts of Bullitt East students.
Local Boy Scouts teamed up with the Bullitt County Woman's Club to do some landscaping at the Bullitt County Detention Center on Saturday, June 6.
Scouts from Shepherdsville Boy Scout Troop 868 and Cub Scout Pack 868 turned out early Saturday morning to construct four flower beds at the front of the jail.
A landscaping plan had been prepared by the Bullitt County Woman's Club in consultation with the local Master Gardener Association and the Bullitt County Extension Office.
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The Pioneer News Online is your source for local news, sports, events and information in Bullitt County and Shepherdsville, KY, and the surrounding area.

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For CBS, the three-man booth works
CBS' first three-man announcing team for the NCAA men's basketball Final Four wasn't grating Saturday.
Instead, Jim Nantz and Clark Kellogg and newcomer Steve Kerr, on hand via the new CBS/Turner partnership, were largely deferential with each other, proving to be easy listening rather than overbearing.
"The three-man booth is very different," Kerr said Sunday. "It either works or it doesn't, depending on the chemistry. In this case, it worked well. With Clark and I, neither of us has a problem deferring. There's no ego involved. If he says something I'm already thinking, I don't care."
Kellogg agreed Sunday: "The chemistry was fine, and we had a good time. And the games were close, if not superbly played."
And, he noted, viewers weren't seeing something completely new because NBC's team of Dick Enberg, Billy Packer and Al McGuire three decades ago was "one of the best (on-air teams) of all time."
Given the NCAA runs from teams with underwhelming regular seasons, fans might conclude there's no need to follow college hoops until the tournament or that the tournament field needs to be expanded. "It probably will expand," Kerr said. "But I hope not." Kellogg agreed: "We're where we need to be for a while."
But Kerr also suggested the so-called First Four could be tweaked: "Have all eight teams in those from power conferences — just the bubble teams rather than league winners — going head-to-head."
And Kerr said, "It's almost unfair that it's all about the NCAA tournament now. Kansas ends up 35-3 after getting to the Elite Eight, and a lot of people feel their season was a failure."
Charles Barkley predicted Saturday that we would not see another First Four team make the Final Four, but then he also predicted Virginia Commonwealth and Kentucky would win. Kerr said: "It wouldn't shock me if we saw something like this again. There's so much parity."
For tonight's final, Kerr won't make a prediction because he's calling the game but said Butler "looks like the most solid team out there." Kellogg said pick 'em: "It's a real toss-up."
NCAA ratings:
Upsets produced the first Final Four without a No. 1 or No. 2 seed, but you wouldn't know there was anything unusual from the TV ratings. CBS drew an 8.3 national rating for Butler's win, translating into 8.3% of TV households, down 3% from last year's Butler-Michigan State game. Connecticut-Kentucky drew 9.5%, up 3% over Duke-West Virginia. Overall, CBS drew an 8.9, the same as 2010.
Spice rack:
After Fox's Major League Baseball coverage Saturday replayed Super Bowl footage of Alex Rodriguez and actress Cameron Diaz touchingly sharing popcorn, Joe Buck addressed reports Rodriguez had complained to Fox: "A-Rod never called anyone here to complain. I've been trying to call that same number here since 1994, and trust me, nobody answers." …Steve Phillips, discussing the Barry Bonds trial on his Sirius XM radio show, said, "Thank God for steroids. It brought the game back from extinction." So if baseball has been cleaned up, it's now in terminal condition? … Driver Martin Truex Jr., on Fox on Sunday, praised NASCAR improvements after he walked away from a fiery crash: "Ten years ago, I wouldn't be standing here" after such a crash. And he sounded like he meant it. …ESPN suspended Jalen Rose after he failed to tell the network he'd been cited for DUI. After the news was broken by a Detroit TV station, Poynter Review Project — ESPN's ombudsman — noted ESPN doesn't have a policy requiring announcers to "tell their bosses about potentially embarrassing personal issues." But it also noted ESPN announcers were told they need to tell ESPN about their "situations." So, presumably, ESPN can report them first.
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(CNN) -- Juan Pablo Montoya has won the 99th Indianapolis 500.
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Rachael Farrokh, 37, who suffers from a severe form of anorexia and weighs roughly 40 pounds, has raised more than $120,000 for her treatment with a GoFundMe page.
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Forget politics and religion. One of the biggest debates on Wall Street these days is whether oil and energy stocks are toxic or terrific.
Bank of America Merrill Lynch put out a note last week telling clients now is the time to buy. Hedge funds have ...
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Caravan and tent Camping on the river
Come with your family for a getaway filled with fun and relaxation. Nothing like the great outdoors .Caravan Camping at its best .The Vaal River at your footsteps .. Bird watching , Fishing and more . Or just Relax next to the Swimming Pool .
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Luxury Tented Camp site : The Luxury Tented Camp Site sleeps 5 people in the main Tent and extra dome tents can be rented that can sleep 4 people without beds or 2 people with beds. Price per extra dome tent will be additional R 200 per tent and R 150 per bed with mattress ( we do not supply the Bedding ) just bring your own bedding and cutlery .. beds are fitted with fitted sheets.
The Luxury camp site has its own Private Boumas / Lapa area and the main tent has its own on-suite Bathroom with a outside shower . max people on the camp site 5 people in main tent and 6 people in additional dome tents .
Extras : Rent …. Dome Tents R 200 per tent per night …. Beds … R 150 per night with mattress …. These Extras can be added on to any site
Day Visitors R 80 per person ( day visitors only allowed till 5 pm )


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Double Vision Center - Bloomington, IN
WebMD Physician Directory
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Double Vision
What is double vision?
Double vision is the perception of two images of a single object seen adjacent to each other (horizontally, vertically, or obliquely) or overlapping. Double vision is medically termed diplopia. Polyplopia is the pe...
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Joint Aspiration Center - Midland, TX
Midland Orthopedic Surgeon Doctors for Joint Aspiration
Type of Physician: Orthopedic Surgeon
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Tsonga overpowered fellow countryman Richard Gasquet to meet Federer
Roger Federer tamed big-serving Canadian Milos Raonic while Andy Murray showed an ailing Gilles Simon no mercy as they swept into the Australian Open quarter-finals on Monday.
The pair were joined by Jeremy Chardy and former finalist Jo-Wilfried Tsonga, who powered past another Frenchman Richard Gasquet to set up a meeting against 17-time Grand Slam king Federer. The Swiss ace was forced through a tough second set tiebreak by Raonic but held his nerve and raced to 6-4, 7-6 (7/4), 6-2 win in 1hr 53min to reach his 35th consecutive Grand Slam quarter-final.
Murray too good for Simon
US Open champion Murray was too physical for the troubled French 14th seed Simon, still struggling after a marathon match over the weekend, as he won 6-3, 6-1, 6-3 in 1hr 35min. Simon was barely mobile around the court following Saturday's nearly five-hour win over fellow Frenchman Gael Monfils, and he was a spent fo rce late in the match.
Simon was sanguine about his exit. "It was just difficult for me today. I just did all I could for the last two days to be able to play this one," he said. "It was a painful hour-and-a-half on the court. Andy is a very good player so it's always very hard to beat him. Without being 100 percent you have almost no chance to do it."
Murray largely did as he pleased, breaking Simon three times in the opening set, another three times in the second and two more in the final set.
He now faces up to the 36th-ranked Chardy in the last eight, following the Frenchman's four-set win over Italian 21st seed Andreas Seppi earlier on Hisense Arena. Chardy's previous best performance at a major was his fourth-round appearance at the French Open in 2008, when he lost to Spaniard Nicolas Almagro.
Tsonga praises coach
Meanwhile Tsonga sang the praises of new coach Roger Rasheed as he stepped up his campaign for a maiden Grand Slam win. The 2008 runner-up was too strong for ninth seed Gasquet, winning 6-4, 3-6, 6-3, 6-2 in 2hr 20min on Rod Laver Arena. Tsonga said his game was benefiting from working with his new Australian coach Rasheed, the former mentor to Lleyton Hewitt and Gael Monfils, as he seeks his Grand Slam breakthrough. "He's giving me an extra motivation. It's great because he's always positive. He wants maybe more than me to win. He's incredible…" Tsonga said.AFP


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28th June 2013
David Cameron: Gay and lesbian young people will see that they are truly equal after marriage law changes 18
11:34 AM — Prime Minister David Cameron says implementing equal marriage means gay and lesbian students "will be able to see that Parliament believes their love is the same as anyone else's love."
25th June 2013
Poll: UK support for equal marriage at 55% 18
2:04 PM — A new poll by Ipsos of 16 countries puts support for equal marriage in the UK at 55%.
22nd June 2013
Tory MPs write 'alternative queen's speech' urging referendum on equal marriage 80
5:02 PM — Conservative MPs have drawn up an 'alternative queen's speech', including policies to hold a referendum on equal marriage, bring back the death penalty, ban the wearing of burkas in public and to rename a public holiday after Margaret Thatcher.
17th June 2013
David Cameron to discuss Nigeria's new anti-gay law with country's politicians and leaders 7
2:15 PM — Following the decision of Nigeria's lawmakers to pass a new anti-homosexuality law, Prime Minister David Cameron says "nothing should be off the table" when it comes to foreign aid and protecting equal rights.
15th June 2013
Gay rights opponent Tory MP Edward Leigh knighted in Queen's Birthday Honours list 56
12:13 PM — Edward Leigh, Conservative MP for Gainsborough, one of the fiercest critics of equal rights for lesbian and gay people, has been awarded a knighthood in the Queen's Birthday Honours list.
11th June 2013
Daily Mail's Andrew Pierce: I'm called a 'homophobe' and 'Uncle Tom' for opposing equal marriage 103
12:18 PM — As part of a feature for the BBC News website entitled "The gay people against gay marriage" Daily Mail columnist Andrew Pierce says his opposition to equal marriage means he's denounced by his critics as a "homophobe and Uncle Tom".
10th June 2013
Tory MP Andrew Bridgen: Equal marriage is the last straw, Cameron has to go 35
5:07 PM — Conservative MP Andrew Bridgen says Prime Minister David Cameron's championing of equal marriage "has fuelled the rise of UKIP" and he has asked for a no confidence vote.
Baroness Knight: The gays are still good at antiques and Section 28 was right 61
10:53 AM — Baroness Knight shows no sign of looking to curb her bizarre attempts at making platitudes towards the gay community following her comments during the House of Lords equal marriage debate.
7th June 2013
Labour Lord Alli: We won the equal marriage vote but there is still a long way to go 26
2:40 PM — Writing exclusively for PinkNews.co.uk, Labour peer Lord Alli, the first openly gay peer to be appointed, says he was stunned by the House of Lords decision to support the Marriage (Same Sex Couples) Bill with such an overwhelming majority, and has paid tribute to Conservative peer Lord Jenkin for his powerful equal marriage speech.
Ashcroft poll: Only 15% would be less likely to vote for a party due to its support for equal marriage 12
12:01 PM — A new poll by Conservative peer Lord Ashcroft suggests equal marriage is unlikely to draw voters away from supporting a particular party.
6th June 2013
Ann Widdecombe: I wouldn't have enjoyed serving under David Cameron because of equal marriage 65
8:38 PM — Former Conservative MP Ann Widdecombe says she wouldn't have enjoyed being in the current Coalition Government because of its support for equal marriage.
4th June 2013
Labour Lord Alli: 'A stunning victory for equal marriage in the Lords' 13
7:21 PM — Lord Alli has described the passing of the Marriage (Same Sex Couples) Bill at second reading in the House of Lords as "a stunning victory for equality".
Labour Lord Alli praises David Cameron over his 'courageous' support for equal marriage 4
5:02 PM — Labour peer Lord Waheed Alli has paid tribute to Conservative Prime Minister David Cameron over his "courageous" support for equal marriage.
3rd June 2013
Yvette Cooper: The government needs to remember who the real opponents of equal marriage are 11
10:18 AM — Shadow Home Secretary Yvette Cooper has told PinkNews.co.uk that the government needs to remember "who the opponents are" of the same-sex marriage bill in the wake of last week's row about House of Lords timetabling.
2nd June 2013
Tory Grassroots warn equal marriage will smash family values 74
9:33 AM — Tory activists have urged the House of Lords to reject the same-sex marriage bill in Tuesdays vote, arguing it will weaken the bringing up of children and devalue the family.
1st June 2013
Religious leaders urge David Cameron to drop equal marriage bill before Lords debate 66
7:03 PM — Fifty British faith leaders have come together to sign a letter urging the Prime MInister to drop the Marriage (same sex marriage) Bill, before it goes to the House of Lords next week for its second reading.
Comment: How I campaigned to change the age of consent a world away from equal marriage, by Edwina Currie 21
5:14 PM — Ahead of next week's historic vote on same-sex marriage, PinkNews asked former Conservative Health minister Edwina Currie, who fought against the odds to change the age of consent in 1994, to reflect on her battle.
30th May 2013
Clare Balding takes aim at 'uncool' Lord Tebbit over his 'lesbian queen' remarks 43
1:28 PM — Clare Balding has criticised Lord Tebbit after he warned Britain could be ruled by a lesbian queen if equal marriage is legalised, she says the remarks are "insulting to every surrogate parent".
26th May 2013
Top Conservative donors threaten to quit party over equal marriage bill 24
2:33 PM — The Conservative Party is facing more turmoil as some of its top donors have threatened to quit the party over issues such as equal marriage.
25th May 2013
Labour MP Diana Johnson: It's now time for Parliament to tackle the issue of gay conversion therapy 36
12:45 PM — With marriage equality on its way, Labour MP Diana Johnson and Tom Stephens both write for PinkNews.co.uk on why ending gay-to-straight conversion therapy should be Parliament's next priority.


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Montes Napa Angel Aurelio's Selection Cabernet Sauvignon 2006
Cabernet Sauvignon from Napa Valley, California
Winemaker's Notes
Napa Angel Aurelio´s Selection is 100% Cabernet Sauvignon from the Napa regions of Oak Knoll and Yountville. The soil in these areas is predominantly gravel with a proportion of alluvial loam that helps to achieve harmonious and balanced wines. The climate during the 2006 vintage – moderately warm with cold nights – helped the development of ripe fruit flavors and deep color. Aurelio regularly visited the estates controlling and checking the full phenolic ripeness of the grapes. Yields were 2.5 tons per acre, hence the full-bodied character of the wine. The grapes were carefully selected and hand-picked.
After harvesting, the grapes were cold macerated for 10 days and then fermented for another 10 days. The wine went through a process of post fermentation skin contact. 80% of the wine was aged for 18 months in new French oak barrels.
Full-bodied wine with firm, soft tannins. Deep and intense garnet red. Rich and harmonious with an integrated, mature and mellow fruit character that makes this wine elegant and silky and opulent at the same time. In the mouth-feel it has a lingering character given by the Oak Knoll and Yountville gravely terroirs. Generous fruit expression with hints of blackberries, plums and layers of black cherries. Velvety in the mid palate, with nuances of perfectly integrated French oak. Nice long finish. A wine to be aged for at least 15 years or to be enjoyed now.
Critical Acclaim
Wine Enthusiast - "Full-bodied wine with firm, soft tannins. Deep and intense garnet red. Rich and harmonious with an integrated, mature and mellow fruit character that makes this wine elegant and silky and opulent at the same time. In the mouth-feel it has a lingering character given by the Oak Knoll and Yountville gravely terroirs. Generous fruit expression with hints of blackberries, plums and layers of black cherries. Velvety in the mid palate, with nuances of perfectly integrated French oak. Nice long finish. A wine to be aged for at least 15 years or to be enjoyed now."
Connoisseurs' Guide - "Chilean winemaker, Aurelio Montes, joins an elite crowd of high-achievers in Napa Valley with a stunning pair of new Cabernet releases. This, the winery's flagship bottling, is a substantial and serious wine by any and all measures, and its combination of concentrated curranty fruit, lavish oak and rich, loam and tobacco-leaf qualities will win loud applause from all who champion hedonistic, optimally ripened, fullflavored Cabs. For all of its up-front appeals, however, it is a solidly structured wine that cries out for age, and it is bound to get better for a decade or more."
Montes Winery
With the release of the first Montes Alpha wine back in 1988, Montes became one of the first premium wineries of Chile. Their premise, a clear belief that Chile had an untapped potential as a producer of quality wines, made them a benchmark for other wineries to follow. Its original four partners' total involvement and the continuous help of the angels that decorate their labels was key to their success. Two decades later, Montes is the fifth most important winery of Chile where Aurelio Montes continues leading the winemaking area with the same passion as the first day. Hard work and total focus on quality has led Montes to be one of the most successful and respected quality-driven wineries in Chile as they continue pioneering and breaking new grounds in wine. View all Montes Wines
About Napa ValleyView a map of Napa Valley wineries
It's hard not to think of Napa Valley when thinking of California wines. The region is, after all, the one that brought world recognition to California wine making. The area was settled by a few choice wine families in the 1960's who bet that the wines of the area would grow and flourish. They were right. The Napa wine industry really took off in the 1980's, when vineyard lands were scooped up and vines were planted throughout the county. A number of wineries emerged, from large conglomerates to small boutiques to cult classics. Cabernet Sauvignon is definitely the grape of choice here, with many winemakers also focusing on Bordeaux Blends. Whites are usually Chardonnay and Sauvignon Blanc.
Notable FactsWithin the Napa Valley lie smaller sub-AVAs that lend even more character specifics to the wines. Furthest south is Carneros, followed by Yountville, Oakville & Rutherford. Above those two is St.-Helena and finally, just grated an AVA, Calistoga. These areas are situated on the valley floor and are known for creating rich, smooth Cabernet Sauvignon, Merlot and Chardonnay. There are a few mountain regions as well, nestled on the slopes overlooking the valley AVAs. Those include Howell Mountain, Stags Leap and Mount Veeder. Wines from the mountain regions are often more structured and firm, benefiting from more time in the bottle to evolve and soften.
About South AmericaRelated Links:
Young, organically farmed Carmenère at Chile's De Martino estate vineyard
Customer ReviewsSign In to Add Your Review5 }div>5 out of 5 stars
- 5 Stars: 1
- 4 Stars: 0
- 3 Stars: 0
- 2 Stars: 0
- 1 Stars: 0
1 rating, 0 with reviewsPaul Levine - Mamaroneck, NY59/30/2010
Alcohol By Volume GuideMost wine ranges from 10-16% alcohol by volume. Some varietals tend to have higher (for example Zinfandel and Cabernet Sauvignon) or lower alcohol levels (Pinot Noir and many white varietals), but there is always some variation from producer to producer. Some wine falls outside of this range, for instance Port weighs in closer to 20%, while Muscat and Riesling are usually a bit below 10%.
Wine Style Guide
Light & Fruity
- Red wines that are more fruit-forward and lighter in tannin and body.
Smooth & Supple
- Medium bodied reds that go down easy, with smooth tannins and supple fruit.
Earthy & Spicy
- Wines where earthy and/or spicy dominate the flavors – typically medium to full body.
Big & Bold
- Full bodied wines that have concentrated fruit and are higher in alcohol and/or tannins. Some need age.
- 5 Stars:


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January 8th,
8:00 p.m. ET, Fox
BCS Championship History
2008 LSU 38, Ohio State 24
2007 Florida 41, Ohio State 14
Tickets for the BCS Championship
CFN 2009 BCS Championship Preview
Richard Cirminiello
Best Gator
Bowl Moment:
How good was the 41-14 thumping of Ohio State in the BCS
Championship Game two years ago? Good enough to trump the 52-20
annihilation of No. 1 and unbeaten Florida State in the 1997 Sugar
Bowl as the best moment in Florida bowl history. Considered by many
to be out of the top-ranked Buckeyes' league, the Gators feasted on
their slower opponent, holding Heisman Trophy winner Troy Smith and
Ohio State to just 82 yards of total offense.
Best Sooner Bowl Moment: Although the last four BCS bowl
appearances have been eminently forgettable, OU's 24-16-1 bowl
record ranks among the best of any program with at least 15
appearances. The Sooners, regulars in Miami throughout the years,
used the 2001 Orange Bowl as a vehicle to regaining their status as
a perennial national title contender. The Oklahoma defense
suffocated high-powered Florida State in a shocking 13-2 win that
captured the school's seventh national championship.
The Last Time You'll See ...
LG Duke Robinson. While the skill position Sooners make all of the
headlines, Robinson and the rest of his linemates have done their
part to make the offense percolate in 2008. A 6-5, 335-pound mauler,
he's been a starter for three seasons, earning All-America honors at
the end of the last two. Next spring will be about revamping an
offensive line that'll go down as one of the best in school history.
WR Percy Harvin. As injury-prone as Harvin has been throughout his
college career, why risk playing another season in Gainesville
without getting paid? If he decides to leave that final year of
eligibility on the table and tests well at the Combine, he has the
electrifying speed and off-the-charts ability as a playmaker to be
scooped up in the first round.
Breakout Player ...
Florida: CB Janoris Jenkins. You know you're special when
you start at Florida as a true freshman. Jenkins is one of those
rare gems on the Gator defense. He has already exceeded expectations
in his first year, blanketing opposing receivers and continuously
improving as the season has progressed. He's got the hips, speed,
and confidence to be one of the best corners in the SEC as early as
next year.
Oklahoma: WR Ryan Broyles. While he sort of got lost in a
receiving corps that included Juaquin Iglesias, Manny Johnson, and
Jermaine Gresham, Broyles was still able to make the first 42 grabs
of his career for 661 yards and six touchdowns. He's loaded with
speed, explosiveness, and upside potential, all of which will become
more obvious once this year's starters graduate.


text:
Clearly my message is not being heard.
I've emphasized repeatedly the importance of "staging" to make your home appealing to the highest number of potential buyers. That is, declutter, depersonalize and set a trap for buyers, paying attention to how your house appeals to all five senses.
After showing 21 Orange County houses in the last three days, it's clear too many home sellers have not gotten the message.
Rather than go on another rant, I figured you might enjoy the specific details about what I've seen recently. You tell me if these people have any interest in getting their house sold for as high a price as possible in as fast a time as possible.
The smelly
Actually, this week there were two winners in the smelliest house on the market category.
Both had me at the front door. Pungent, acrid, heavy, offensive, nauseating, and eye-wateringly smelly houses. The reek of garlic, grease, and spices strong enough to permeate every pore of the property.
I suggested my clients might consider a thorough washing.
The messy
At least one open suitcase, with the contents on display, in every single room, including the dining room, living room and family room.
Dirty laundry piled up in the hall way. A queen-sized mattress sitting on its side, leaning against the upstairs hallway banister, conveniently blocking the view of the downstairs entry way.
Remnants of breakfast decorating the kitchen counter. Dishes piled up in the sink – not in any harmonious fashion and devoid of any distinguishable color scheme. Books strewn about the floor, abandoned for other pastimes.
Personal care items scattered willy-nilly on the bathroom counters.
Dog poop resting on the front lawn -- and on the front porch.
A hot mess.


text:
Tirumala Tirupati Devasthanams: Discourses on Ayodhya Kanda and music concert, Thirunilayam Himayatnagar 5 p.m.
Tirumala Tirupati Devasthanams: Sangeetam, TTD Balaji Bhavan, Himayathnagar, 6.30 p.m.
Vyakti Vikas Kendra: Sri Sri Yoga course, Sindhi Colony, 6.30 a.m.
Media Junction: Speaking skills workshop for children, Partani Towers, Musheerabad, 10 a.m.
Hyderabad Management Association: Talk on Leveraging Intellectual Property for Nations Economic Growth, FAPCCI, Red Hills, 6.30 p.m.
Plan: State-level consultation with children on HIV and AIDS, St. John's Seminary, Ramanthapur, 9.30 a.m.
FAPCCI: Seminar on 'How to Hedge Currency Risk', FAPCCI, Red Hills, 10 a.m.
Kamineni Hospitals: Discourse on Yoga, Indira Auditorium, Kamineni Hospitals, L.B. Nagar, 4 p.m.
Sri Venkateshwara, Sri Yogeshwara Devasthanams: 601 Jayanthi celebrations of Saint Annamacharya , Hari Hara Gana Sabha, BHEL Temple Complex, R.C. Puram, 5 p.m.
Sri Lakshmi Narasimha Swami Seva Samiti: Fifth mega musical festival, Keyes High School, Secunderabad, 6.30 p.m.
Shilparamam: Vocal music by Reddy Sisters, Shilparamam, Madhapur, 7 p.m.
Department of Culture: Shastriya Sangeetha Nritya Saptaaham, Ravindra Bharati, 6.30 p.m.
ICONART Gallery: Preview of an exhibition of paintings, 'The Buddha Speaks' by Prakaash Chandwadkar, ICONART Gallery, SBI Building, Road No. 12, Banjara Hills, 7 p.m.


text:
Jessica Mendoza officially retires from softball
In her mind, Jessica Mendoza knew she was done playing softball. It just took her three months to verbalize it to the rest of the world.
Putting an end to one of greatest softball careers of all time, Mendoza, 33, officially announced her retirement Friday morning.
The Camarillo High graduate most recently played for the USSSA Pride in National Pro Fastpitch in 2012 before sitting out the 2013 season while pregnant with her second son, Cayden.
Mendoza realizes many people already thought she was retired from playing, but wanted to make it absolutely clear.
"It's nice to just make the decision. I can't even tell you how much I have been mulling it since Cayden was born," said Mendoza, who will remain working as a broadcaster for ESPN and the Pac-12 Network. "Every day I would wake up and wonder, 'Am I coming back or not?' I was constantly going back and forth with the pros and cons. What it really came down to is I wouldn't be able to do the game justice by committing full time anymore."
Mendoza started her softball career 26 years ago playing in the Camarillo Girls Softball Association at Mission Oaks Park, where her small jersey is retired on the backstop.
She was an All-CIF player at Camarillo High before becoming a four-time first-team All-American at Stanford from 1999 to 2002.
As a member of the U.S. national team, Mendoza won two Olympic medals — gold in Athens in 2004 and silver in Beijing in 2008 — and three straight world championships.
She captured an NPF title with the Pride in 2010 and earned Most Valuable Player honors in 2011.
Mendoza's official retirement comes long after she initially thought her career would end.
"There was a time when I thought I would be done after high school," said Mendoza, who was inducted into the Ventura County Sports Hall of Fame last year. "I didn't think any college coaches would ever want me. That is how insecure and crazy I was. I doubted my ability and thought I would maybe play in junior college."
During Mendoza's first few months with the U.S. national team, veterans Lisa Fernandez and Laura Berg pulled her into their hotel room for a talk.
"They asked, 'Are you a lifer?' I didn't know what they meant. They told me a lifer means someone who cares about the game so much they just play it for life. They play forever," Mendoza said. "They said they could tell I was one of those kinds of people. I remember thinking, 'Yeah., that is exactly what I am.' "
Although Mendoza may not technically play for life, she will remain involved in the sport forever.
She remains eternally grateful for the opportunities softball has provided — from the world travel and the lasting friendships to the ability to impact so many lives.
"As much as I would love to be Derek Jeter and have this perfect retirement with 162 games of goodbyes, it doesn't always work out that way," Mendoza said. "I think when I look back I am just so happy that I was able to play for as long as I did and have so many great memories."
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text:
Graff Diamonds Said to Win Nod for $1 Billion H.K. IPO
May 4 (Bloomberg) -- Graff Diamonds Ltd. gained approval from Hong Kong's stock exchange for a plan to raise as much as $1 billion in an initial public offering, said two people with knowledge of the matter.
The London-based jeweler may start gauging investor demand in the next two weeks, said the people, who declined to be identified because the process is private.
In seeking to list in Hong Kong, where Chinese consumers take advantage of lower tax rates than in the country's mainland and splurge on luxury goods, Graff is following the footsteps of luxury retailer Prada SpA. Prada, the Italian fashion house that raised about $2.1 billion in June, has gained 34 percent from its IPO price.
Credit Suisse Group AG, Deutsche Bank AG, Goldman Sachs Group Inc. and Morgan Stanley are managing the planned offering, the people said. Officials at Graff's London office couldn't immediately be reached to comment.
Graff runs a store in the Peninsula Hotel in Hong Kong. Founder and London jewelry dealer Laurence Graff bought a diamond in a 2010 sale for a record auction price of 45.4 million Swiss francs ($50 million). Graff had also paid 16.4 million pounds ($27 million) for the 35.56-carat grayish-blue Wittelsbach Diamond at Christie's International in London in December 2008, then the highest price for a gem at auction.
To contact the reporters on this story: Fox Hu in Hong Kong at email@example.com; Zijing Wu in London at firstname.lastname@example.com
To contact the editor responsible for this story: Philip Lagerkranser at firstname.lastname@example.com


text:
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In an article in the October/November issue of Society of Corporate and Compliance Ethics Magazine (SCCE), entitled "The seven biggest mistakes companies make that erode ethical culture and destroy reputation", author Eric Feldman reviews his version of the Seven Deadly Sins for a company's compliance and ethics program. While noting that the "most severe consequences of corporate ethical lapses can be mitigated, even avoided, by proactive care and feeding of a corporate culture" when a compliance crisis arises it may well be "too late to put the genie back in the bottle." However, by following his seven prescriptions, it may well be the difference between a "bump in the road or falling into quicksand" when the government comes knocking.
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text:
A device and method in which spectral analysis of heart rate variability is performed in order to assess autonomic balance. When a threshold level is reached, a diagnostic mode is triggered in which the device performs computationally intensive data analysis to assess the probability of a pathological event such as an arrhythmia occurring.
1. A cardiac rhythm management device, comprising:
a sensing channel for sensing ventricular electrogram signal and generating a ventricular sense (R wave) when the electrogram signal exceeds a specified threshold value;
circuitry for measuring and collecting time intervals between successive R waves and storing the collected intervals as a discrete RR interval signal;
bandpass filters for filtering the RR interval signal into defined high and low frequency bands;
a power detector for determining the signal power of the RR interval signal in each of the low and high frequency bands, referred to LF and HF, respectively; and,
circuitry for computing an LF/HF ratio and triggering a diagnostic mode if the LF/HF ratio exceeds a predetermined ratio threshold value, wherein upon entering the diagnostic mode, the device activates processing circuitry that performs data analysis to assess the probability of the occurrence of a pathological event.
2. The device of
3. The device of
4. The device of
circuitry for detecting ectopic ventricular beats and computing an ectopic beat density as the ratio of ectopic to non-ectopic beats over a specified time period; and,
wherein the diagnostic mode is triggered only when the ectopic beat density also exceeds a predetermined density threshold value.
5. The device of
6. The device of
7. The device of
8. The device of
9. The device of
10. The device of
11. The device of
12. The device of
13. A method for operating a cardiac rhythm management device, comprising:
sensing ventricular electrogram signals and generating a ventricular sense (R wave) when the electrogram signal exceeds a specified threshold value;
measuring and collecting time intervals between successive R waves and storing the collected intervals as a discrete RR interval signal;
filtering the RR interval signal into defined high and low frequency bands;
determining the signal power of the RR interval signal in each of the low and high frequency bands, referred to LF and HF, respectively; and,
computing an LF/HF ratio and triggering a diagnostic mode if the LF/HF ratio exceeds a predetermined ratio threshold value, wherein upon entering the diagnostic mode, the device activates processing circuitry that performs data analysis to assess the probability of the occurrence of a pathological event.
14. The method of
15. The method of
16. The method of
detecting ectopic ventricular beats and computing an ectopic beat density as the ratio of ectopic to non-ectopic beats over a specified time period; and, triggering the diagnostic mode only when the ectopic beat density also exceeds a predetermined density threshold value.
17. The method of
18. The method of
19. The method of
20. The method of
This application is a continuation-in-part of U.S. patent application Ser. No. 09/850,537, filed May 7, 2001, entitled "Cardiac Rhythm Management System with Arrhythmia Prediction and Prevention," which is a division of U.S. patent application Ser. No. 09/411,345, filed Oct. 1, 1999, now issued as U.S. Pat. No. 6,272,377, and U.S. patent application Ser. No. 09/802,316, filed Mar. 8, 2001, entitled "Cardiac Rhythm Management System Using Time-Domain Heart Rate Variability Indicia," the disclosures of which are hereby incorporated by reference in their entirety.
This invention pertains to methods and apparatus for cardiac rhythm management, which includes the treatment of arrhythmias and the acquisition of diagnostic data.
Cardiac rhythm management devices are implantable devices that provide electrical stimulation to selected chambers of the heart in order to treat disorders of cardiac rhythm. Such devices include pacemakers and implantable cardioverter/defibrillators as well as devices with both types of functionality. Cardiac rhythm management devices have the capability of sensing the intrinsic activity of the heart in order to both deliver certain types of pacing and to detect pathological conditions. Certain devices also have sensors for sensing other physiological variables such as respiratory rate and stroke volume. These devices also have sufficient processing power to perform sophisticated analysis of the data collected by its sensors for the purpose of predicting the occurrence of pathological events, such as an arrhythmia. If such an event is predicted to occur, the device can deliver appropriate therapy and/or alert the patient or clinical personnel. Because implantable devices have limited processing power and are powered by a battery, replacement of which requires re-implantation, it is not practical for a device to continuously perform computation intensive data analysis. It would be useful, therefore, if the device could identify situations where such data analysis would be warranted.
Increased activity of the sympathetic nervous system is associated with metabolic stress and may predispose a susceptible patient to the onset of a cardiac arrhythmia. If increased sympathetic activity could be detected in a patient in whom a cardiac rhythm management device is implanted, a diagnostic mode could then be triggered in which the device performs computationally intensive data analysis to assess the probability of the arrhythmia occurring. It has been found that spectral analysis of heart rate variability can be used to determine the level of sympathetic activity in a subject. Heart rate variability refers to the changes in heart rate that occur during a sinus rhythm (i.e., with normally activated and conducted heartbeats) and is primarily due to the interaction of the sympathetic and parasympathetic nervous systems. Low frequency variation in heart rate is due to both parasympathetic (or vagal) and sympathetic activity, while high frequency variation is primarily due to only parasympathetic activity. The ratio of low frequency variation to high frequency variation can thus be used as an indicator of the level of autonomic balance.
A cardiac rhythm management device can be programmed to measure and collect the time intervals between successive ventricular senses, referred to as RR intervals, for a period of time or a specified number of beats. The resulting series of RR interval values is then stored as a discrete signal and either used directly as indexed by heartbeat or resampled at a specified sampling frequency in order to equalize the time intervals. The RR interval signal can then be analyzed to determine its energies in the high and low frequency bands as described above. Although spectral analysis of an RR interval signal can be performed directly in the frequency domain, a time-domain technique for determining the signal power in defined high and low frequency bands is preferably used for reasons of computational economy. If the ratio of low frequency power to high frequency power exceeds a predetermined threshold value, a diagnostic mode in the device is triggered.
The above summary is intended to provide an overview of the subject matter of the present patent application. It is not intended to provide an exhaustive or exclusive explanation of the invention.
The present invention relates to a method for triggering a diagnostic mode in a cardiac rhythm management device. What follows is a description of the method as well as of the hardware components and operating modes of a device in which the method may be implemented.
1. Hardware Platform
In the embodiment to be described, the invention is implemented with a controller made up of a microprocessor executing programmed instructions in memory. It should be appreciated, however, that certain functions of a cardiac rhythm management device could be controlled by custom logic circuitry either in addition to or instead of a programmed microprocessor. The term "circuitry" as used herein should therefore be taken to encompass either custom circuitry (i.e., dedicated hardware) or a microprocessor-based controller executing programmed instructions contained in a processor-readable storage medium.
Pacemakers and other types of implantable cardiac rhythm management devices are typically implanted subcutaneously or submuscularly in a patient's chest and have leads threaded intravenously into the heart to connect the device to electrodes used for sensing and pacing. Leads may also be positioned on the epicardium by various means. A programmable electronic controller causes the pacing pulses to be output in response to lapsed time intervals and sensed electrical activity (i.e., intrinsic heart beats not as a result of a pacing pulse). Pacemakers sense intrinsic cardiac electrical activity by means of internal electrodes disposed near the chamber to be sensed. A depolarization wave associated with an intrinsic contraction of the atria or ventricles that is detected by the pacemaker and exceeds a specified threshold is referred to as an atrial sense or ventricular sense, respectively. In order to cause such a contraction in the absence of an intrinsic beat, a pacing pulse (either an atrial pace or a ventricular pace) with energy above a certain pacing threshold is delivered to a heart chamber.
A block diagram of a multi-site pacemaker having three sensing/pacing channels is shown in FIG. 1. (As the term is used herein, a "pacemaker" should be taken to mean any cardiac rhythm management device, such as an implantable cardioverter/defibrillator, with a pacing functionality.) The controller of the pacemaker is made up of a microprocessor 10 communicating with a memory 12 via a bidirectional data bus, where the memory 12 typically comprises a ROM (read-only memory) for program storage and a RAM (random-access memory) for data storage. The controller could be implemented by other types of logic circuitry (e.g., discrete components or programmable logic arrays) using a state machine type of design, but a microprocessor-based system is preferable. The controller is capable of operating the pacemaker in a number of programmed modes where a programmed mode defines how pacing pulses are output in response to sensed events and expiration of time intervals. A telemetry interface 80 is also provided for communicating with an external programmer.
The multiple sensing/pacing channels may be configured to deliver biventricular pacing, biatrial pacing, or multi-site pacing of a single chamber. Illustrated in
The controller 10 controls the overall operation of the device in accordance with programmed instructions stored in memory and with information derived from the sensing channels. The voltages sensed by the sensing electrodes are electrogram signals that are analogous to a surface ECG and provide a temporal record of cardiac depolarization and repolarization that occurs during either intrinsic or paced beats. The sensing circuitry of the pacemaker generates atrial and ventricular senses when voltages sensed by the electrodes of a particular channel exceed a specified threshold. A ventricular sense would correspond to an R wave on an ECG, and an atrial sense would correspond to a P wave. The controller 10 interprets sense signals from the sensing channels in order to detect arrhythmias and to control the delivery of paces in accordance with a pacing algorithm that employs such senses to trigger or inhibit pacing.
When an arrhythmia is detected, the controller may cause appropriate therapy to be delivered. For this purpose, the device in
2. Operating Modes and Configurations
The device illustrated in
Bradycardia pacing modes refer to pacing algorithms used to pace the atria and/or ventricles in a manner that enforces a certain minimum heart rate. Pacemakers can enforce a minimum heart rate either asynchronously or synchronously. In asynchronous pacing, the heart is paced at a fixed rate irrespective of intrinsic cardiac activity. There is thus a risk with asynchronous pacing that a pacing pulse will be delivered coincident with an intrinsic beat and during the heart's vulnerable period which may cause fibrillation. Most pacemakers for treating bradycardia today are therefore programmed to operate synchronously in a so-called demand mode where sensed cardiac events occurring within a defined interval either trigger or inhibit a pacing pulse. Inhibited demand pacing modes utilize escape intervals to control pacing in accordance with sensed intrinsic activity. In an inhibited demand mode, a pacing pulse is delivered to a heart chamber during a cardiac cycle only after expiration of a defined escape interval during which no intrinsic beat by the chamber is detected. If an intrinsic beat occurs during this interval, the heart is thus allowed to "escape" from pacing by the pacemaker. When the intrinsic cardiac rhythm is such that escape beats occur, the device senses intrinsic beats through its sensing channels.
In response to the detection of a tachyarrhythmia, the device may pace in the heart with an anti-tachycardia pacing (ATP) mode. In ATP, the heart is competitively paced with one or more pacing pulses in an effort to interrupt reentrant circuits causing the tachyarrhythmia. Generally, only cardioversion/defibrillation will terminate fibrillation and certain high rate tachyarrhythmias, while ATP can be used to treat lower rate tachyarrhythmias. A rate-based criterion may thus be used by the device to decide whether to deliver ATP therapy or a defibrillation shock.
Cardiac resynchronization therapy is pacing stimulation applied to one or more heart chambers in a manner that restores or maintains synchronized contractions of the atria and/or ventricles. Certain heart failure patients suffer from interventricular and/or intraventricular conduction defects that cause the ventricles to beat in an uncoordinated manner. Ventricular resynchronization pacing is useful in treating these patients because, although not directly ionotropic, resynchronization results in a more coordinated contraction of the ventricles with improved pumping efficiency and increased cardiac output. Resynchronization pacing of the atria may also be beneficial in some heart failure patients, particularly for preventing the onset of atrial arrhythmias. One way to deliver resynchronization therapy is to pace a site with a synchronous bradycardia pacing mode and then deliver one or more resynchronization paces to one or more additional pacing sites in a defined time relation to one or more selected sensing and pacing events that either reset escape intervals or trigger paces in the bradycardia pacing mode.
3. Data Analysis for Event Prediction
An implantable cardiac rhythm management device with cardiac sensing channels such as that illustrated in
Data recorded from sensing channels can also be analyzed by the device in order to predict the occurrence of pathological conditions such as arrhythmias. In a particular scheme for doing this, an arrhythmia is predicted by: 1) detecting a conditioning event statistically associated with the occurrence of an arrhythmia in a patient's heart; 2) computing a conditional arrhythmia probability for the conditioning event from past observations of instances in which the conditioning event occurs alone or together with an arrhythmia within a specified time period; 3) computing an estimated arrhythmia probability based upon the detected occurrence of the conditioning event; and 4) predicting the occurrence of an arrhythmia within a specified prediction time period if the estimated arrhythmia probability exceeds a specified threshold value.
Conditioning events may be broadly classified into markers and triggers. A marker event corresponds to a detected physiological state that is statistically associated with occurrence of cardiac arrhythmias, but the causal relationship between the marker and the arrhythmia is not known. A conditioning event is regarded as a trigger, on the other hand, if the event is thought to increase the risk of an arrhythmia occurring via a depolarization that serves as a source for the arrhythmia. Conditioning events may be detected on a beat-to-beat basis or over a longer time frame. Examples of conditioning events include a detected specific morphology of a waveform representing the electrical activity of the heart, a specific pattern of activation times of different areas of the heart as sensed by a plurality of electrodes, a specific sequence pattern of heartbeats with respect to time, a value of a measured physiological variable such as heart rate or blood pressure, or a statistic based upon a history of occurrences of conditioning events.
In one embodiment, the conditional arrhythmia probability is calculated as a ratio of the number of observed instances in which the conditioning event is followed by an arrhythmia within a specified basic time period, to the total number of observed instances of the conditioning event. In that case, the estimated arrhythmia probability for an arrhythmia to occur within the specified basic time period after detection of the conditioning event is simply the calculated conditional arrhythmia probability.
In another embodiment, the conditional arrhythmia probability CP is calculated by the expression:
In another embodiment, rather than basing the estimated arrhythmia probability upon the detection of a conditioning event, a rate at which the conditioning event occurs is detected over some period of time. The estimated arrhythmia probability is then calculated as the product of an estimated probability that a conditioning event will occur times the probability of an arrhythmia occurring within specified time period given the occurrence of the conditioning event (i.e. the conditional arrhythmia probability).Thus:
Another way of deriving a conditional arrhythmia probability, especially for trigger-types of conditioning events (although it can be used with any type of conditioning event), is to designate a particular detected trigger event as being responsible for causing a detected arrhythmia. Such culpability may be assigned based, e.g., upon the proximity in time between the trigger event and the onset of the arrhythmia, the magnitude of the detected trigger, or the frequency of occurrence of the trigger event within a specific time period prior to the onset of the arrhythmia. A conditional arrhythmia probability CP for that trigger event can then be calculated as a ratio of the number of instances in which the trigger event was deemed culpable for causing an arrhythmia, to the total number of occurrences of the trigger event. Also, as above, rather than basing the estimated arrhythmia probability upon the detection of the trigger event, a rate at which the trigger event occurs can be detected over some period of time. The estimated arrhythmia probability is then calculated as the product of an estimated probability that a trigger event will occur times the probability CP of an arrhythmia occurring within a specified time period T given the occurrence of the trigger event. Thus:
In another embodiment, the prediction of arrhythmias is based upon a plurality of the same or different detected conditioning events. A composite estimated arrhythmia probability is then computed as a combination of the estimated arrhythmia probabilities derived for each separately detected conditioning event. The separately detected conditioning events may be separate occurrences of the same or different conditioning events. As before, the composite arrhythmia probability is compared with a threshold value in order to predict the occurrence of an arrhythmia. In one embodiment, the composite arrhythmia probability is calculated by adding the individual estimated arrhythmia probabilities derived for each detected conditioning event, which thus assumes each individual arrhythmia probability to correspond to an independent event. In other embodiments, specific combinations of detected conditioning events are mapped in a non-linear fashion to estimated arrhythmia probabilities that can be added or otherwise combined with other estimated arrhythmia probabilities to give a composite value. In still other embodiments, the estimated arrhythmia probability is computed from a combination of conditional arrhythmia probabilities derived using different basic time periods but for the same prediction time period.
The past observations of the occurrences of conditioning events and arrhythmias from which the conditional arrhythmia probabilities are derived can be taken from either population data or from data collected in real-time from a particular patient. In a preferred embodiment, the conditional arrhythmia probabilities are based initially upon past observations of the occurrences of events and arrhythmias taken from population data, and each probability is subsequently updated from a previous value to a present value with observations taken in real-time from a particular patient. In one embodiment, a conditional arrhythmia probability is updated only if the present value differs by a predetermined amount from the previous value. In another embodiment, the amount by which the present value differs from the previous value is tested for statistical significance before a conditional arrhythmia probability is updated. In another embodiment, the previous value of the conditional arrhythmia probability is incremented or decremented by a specific amount after a prediction time period in accordance with whether the arrhythmia occurred or not, respectively.
In still another embodiment, the statistical association between the conditioning event and the occurrence of an arrhythmia is periodically reevaluated using the most recent patient-specific data. If the statistical association (e.g., as a calculated from a chi-square test) is found to be below a specified value, the use of that conditional arrhythmia probability in deriving a composite estimated arrhythmia probability is discontinued.
4. Triggered Diagnostic Mode
Computational power is limited in implantable medical devices due to a finite battery supply, and it is not practical for such a device to be always performing all of the data analysis that it may be capable of. A diagnostic mode may therefore be defined where such computationally intensive data analysis as described above is performed and which may further include acquisition of additional data from the sensing channels of the device such as high fidelity electrograms for morphology analysis, accelerometer data relating to myocardial contractility or pulse pressure, and transthoracic impedance data relating to respiration patterns and onset of pulmonary edema. It would be beneficial if the device could efficiently detect when conditions are such that the probability of an arrhythmia is increased so that a deeper analysis of the collected data by the diagnostic mode is warranted. Detection of such a condition would then trigger the diagnostic mode in the device where computationally intensive data analysis is performed for predictive purposes.
Increased activity of the sympathetic nervous system, for example, is associated with metabolic stress and may predispose a susceptible patient to the onset of a cardiac arrhythmia. One means by which increased sympathetic activity may be detected is via spectral analysis of heart rate variability. Heart rate variability refers to the variability of the time intervals between successive heart beats during a sinus rhythm and is primarily due to the interaction between the sympathetic and parasympathetic arms of the autonomic nervous system. Spectral analysis of heart rate variability involves decomposing a signal representing successive beat-to-beat intervals into separate components representing the amplitude of the signal at different oscillation frequencies. It has been found that the amount of signal power in a low frequency (LF) band ranging from 0.04 to 0.15 Hz is influenced by the levels of activity of both the sympathetic and parasympathetic nervous systems, while the amount of signal power in a high frequency band (HF) ranging from 0.15 to 0.40 Hz is primarily a function of parasympathetic activity. The ratio of the signal powers, designated as the LF/HF ratio, is thus a good indicator of the state of autonomic balance, with a high LF/HF ratio indicating increased sympathetic activity. By monitoring the LF/HF ratio and initiating computation intensive data analysis for arrhythmia prediction when it exceeds a specified threshold value, the device is able to apply its computational power when it is most needed.
A cardiac rhythm management device can be programmed to determine the LF/HF ratio by analyzing data received from its ventricular sensing channels. The intervals between successive ventricular senses, referred to as RR intervals, can be measured and collected for a period of time or a specified number of beats. In order to derive a signal representing heart rate variability during a sinus rhythm, ectopic ventricular beats (i.e., premature ventricular contractions or PVCs) can be detected by monitoring whether a P wave precedes each R wave, with the RR intervals before and after the PVC changed to an interpolated or otherwise filtered value. The resulting series of RR interval values is then stored as a discrete signal. The signal can be used directly as indexed by heartbeat such that each value of the signal represents an RR interval for a particular heartbeat. Preferably, however, the signal is resampled at a specified sampling frequency in order to equalize the time intervals between signal values and thus convert the signal into a discrete time signal, where the sampling frequency is selected to meet the Nyquist criterion with respect to the frequencies of interest. In any case, the RR interval signal can then be analyzed to determine its energies in the high and low frequency bands as described above.
Spectral analysis of an RR interval signal can be performed directly in the frequency domain using discrete Fourier transform or autoregression techniques. Frequency domain analysis is computationally intensive, however, and may not be practical in an implantable device. A time-domain technique for determining the high and low frequency components of the signal is therefore preferably used.
A diagnostic mode may thus be triggered in the device when the computed LF/HF ratio exceeds a predetermined threshold value. The predetermined threshold value may be fixed or may be determined by the device based upon previous measurements. For example, the LF/HF threshold may be set to 50% of the maximum computed LF/HF ratio value during the previous day. Additional specificity to the criteria for entering the diagnostic mode may be obtained by requiring the detected ventricular ectopic beat density to also exceed a predetermined threshold before triggering the diagnostic mode. The ventricular ectopic beat density may be measured using only interval data by defining it to be the fraction of detected R waves during a period of time that are not preceded by a P wave. The ectopic beat density threshold may either be a fixed value or made dependent upon previous measurements. An exemplary ectopic beat density threshold would be 20% above the daily average of the previous day plus one standard deviation.
Although the invention has been described in conjunction with the foregoing specific embodiment, many alternatives, variations, and modifications will be apparent to those of ordinary skill in the art. Such alternatives, variations, and modifications are intended to fall within the scope of the following appended claims.
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Send an opponent through all three Metropolis transitions in one fight
This can only be done in the Metropolis arena. The trophy / achievement can be unlocked in Practice Mode. Your opponent won't move and time doesn't run out. Dash towards the enemy to push him to the other side of the arena. Once you reach the end, press ← + X (PS3) / ← + A (X360) / ← + B (Wii U) to send the enemy through the transition. There are three transitions in this arena and you have to send the opponent through all of them. The trophy / achievement will pop during the match.
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Products/Services for Cotterless Hitch Pin
Hitch Pins and Linch Pins - (88 companies)...found on vehicle trailers. Hitch Pin and Linch Pin Operation All of the types of pins listed in this selection guide require at least one predrilled hole that is meant to hold and retain objects in place. For coupling... Search by Specification | Learn More
Industrial Pins - (778 companies)...on design and employment, but industrial pins can be categorized into several categories, such as: hitch and linch pins; cotter pins and wire clips; spring pins; locating and fixturing pins; and specialty pins. Industrial Pin Operation. Hitch pins... Search by Specification | Learn More
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No Image AvailableCotter Pins and Wire Clips - (65 companies)...also be used on the vehicle hood. Sometimes hairpins are substituted for linch pins, despite specific pins for this application. They are also used as the locking pin for hitch pins. Circle cotters are designed for use near fabrics and insulated... Search by Specification | Learn More
No Image AvailablePIN Diodes - (67 companies)PIN diodes are three-layer semiconductor diodes consisting of an intrinsic layer separating heavily doped P and N layers. The charge stored in the intrinsic layer in conjunction with other diode parameters determines the resistance of the diode... Search by Specification | Learn More
No Image AvailablePlug and Pin Gages - (195 companies)...and a no-go gauge pin on the opposite end. Progressive or step go/no-go gauges have stepped pins with the go gauge surface and the no-go gauge surface on the same side of the handle. Master gauge blocks, master or setting discs, and setting rings are master... Search by Specification | Learn More
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Product News
Pivot Point, Inc.
Detent Ring Pins Click here to configure & compare products. Ball detent depresses and springs up for "quick release" applications. Used as a convenient way to adjust or remove accessories on equipment. Stocked in zinc plated low carbon steel. Custom pins available in stainless, aluminum, alloy, brass and a variety of finishes. Decades of in-house detent manufacturing experience, as well as qualified import sources manufacturing to our rigid specifications, come together to provide  ... (read more)Browse Hitch Pins and Linch Pins Datasheets for Pivot Point, Inc.
Wood's Powr-Grip Co., Inc.
FLEX Vacuum Lifters composite panels, plywood, particle board, OSB, marble and granite in weights ranging from 600 lbs [270 kg] to 1500 lbs [680 kg], depending on the model purchased. FLEXR4- and FLEXR6- models feature sliding pad arms, to support a variety of material widths by increasing pad spread from side to side. These pad arms make it possible to handle flexible and fragile materials by provide optimal support across the load surface. No tools are required, because cotterless hitch pins make positioning... (read more)Browse Vacuum Lifters Datasheets for Wood's Powr-Grip Co., Inc.
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Pivot Point, Inc.
SLIC Pins™ - A Pin and Cotter All in One Pivot Point's Self Locking Implanted Cotter Pin is a pin and cotter all in one! (US Patent #'s 6,872,039 & 7,147,420. Foreign Patents Issued). . Strong spring-loaded plunger features easy insertion ramp and the vertical face at rear prevents backing out. This patented design is ideal for blind holes or where cotter pin access is limited. The SLIC Pin ™ eliminates cotters, bolts and nuts and does not require tools for use - thereby greatly speeding assembly... (read more)Browse Hitch Pins and Linch Pins Datasheets for Pivot Point, Inc.
Pivot Point, Inc.
SLIC Pins™ Self Locking Implanted Cotter Pin The Self Locking Implanted Cotter Pin is a pin and cotter all in one! (US Patent #'s 6,872,039 & 7,147,420. Foreign Patents Issued). Strong spring-loaded plunger features easy insertion ramp and the vertical face at rear prevents backing out. This patented design is ideal for blind holes or where cotter pin access is limited. The SLIC Pin ™ eliminates cotters, bolts and nuts and does not require tools for use - thereby greatly speeding assembly times. It is well suited... (read more)Browse Cotter Pins and Wire Clips Datasheets for Pivot Point, Inc.
FKN Systek, Inc.
F Series Eurocard Connector - 48 pins at 6A/pin 48 pin F Series Male and Female DIN 41612 are rated at 6A/pin. Available with solder eyelet, Wire Wrap and board solder pins. Now available from 2E SysCom, the F Series 48 pin power DIN rated at 6A per pin. The female connector is available in the standard card cage mountable version and in low profile back plane version. Pin configurations include faston forks which can have the contacts soldered onto the pin or be connected to discrete wiring via faston crimp contact. Solder eyelet wire wrap... (read more)Browse DIN Connectors Datasheets for FKN Systek, Inc.
Pivot Point, Inc.
Detent Clevis Pins assures quality and consistency in function, and we have the ability to adjust ball compression force to translate into a suitable pull-out force in your individual application. Please select the product that you are interested in to learn more and to view stock listings. You can also easily configure a custom product if a stock item does not suit your needs. Quick Release Fastener Solutions include: Clevis Pin | Cotter Pin | Quick Release Pins | Ball Lock Pin | Detent Pins | Hitch Pin... (read more)Browse Industrial Pins Datasheets for Pivot Point, Inc.
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Solid Pins Standard Solid Pins. Specifying SPIROL Solid Pins provides the lowest cost and the most responsive delivery. Tooling and raw material are available to meet your production requirements for all standard parts. Standards include SPIROL Straight Pins, Knurled Pins, Headed Pins and Headed Knurled Pins. Specials. You can rely on SPIROL to be a design partner that helps solve unique problems. Because we supply numerous customers with similar products in similar industries, we... (read more)Browse Dowel Pins Datasheets for SPIROL
Jergens, Inc.
JERGENS QUICK RELEASE PINS Jergens Kwik-Lok ® pins are available in five handle styles: T, L, button, recessed button and ring. Available in corrosion resistant, high strength stainless steel (17-4 PH) as well as in carbon steel. Standard sizes include: Metric - 5 mm to 25 mm outside pin diameters in 10 mm to 100 mm grip lengths. Imperial - 3/16" to 1" outside pin diameters in 1/2" to 6" grip lengths. Special configurations of Kwik-Lok ® pins are available with minimal delay. Jergens is a Department of Defense... (read more)Browse Industrial Pins Datasheets for Jergens, Inc.
Post Installation Tools
These three components are held together with 3/8-inch diameter cotterless hitch pins that can be quickly removed to "knock-down" the assembly for more effective storage and transport.
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The Belkin TuneBase Hands-Free AUX for iPhone 5/5s & iPod touch 5th Generation allows you to play music and make hands-free calls through your car's FM receiver. Use the included cable to connect to your car's auxiliary input. The cradle swivels, so you can view your device in either portrait or landscape mode. It plugs into the 12V power port to charge your device. It has a built-in Lightning connector to make a connection to your device. Additionally, it's compatible with most protective cases. This mount works with iPhones or iPhones with "open-base" cases, meaning that the headphone jack, pin connector and speakers are exposed.
- Play music and make hands-free calls using car stereo
- Connects to car's auxiliary input with included cable
- Built-in Lightning connector to make a connection to your device
- Cradle swivels for viewing in portrait/landscape mode
- Charges through car's 12V lighter outlet
- Fits iPhone 5 and iPod touch 5th generation


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WiFi Probe
50,000 - 100,000 downloadsAdd this app to your listsTweets por @Appszoom
With WiFiProbe, you can simply tap an open network, then WiFi Probe connects to it and checks Internet connectivity. The result is directly shown, there is no need to start a browser or another app. It even identifies captive pages and can thus separate free from password protected wireless networks. Checked networks are stored, so they do not have to be probed one more time when they are found again.
In auto probe mode, WiFi Probe automatically checks all open WiFis it encounters and vibrates when a network providing Internet access has been found or if you are in range of a free network that has already been checked. If you want, WiFi Probe can also immediately connect to the network. Hence, WiFi Probe is the perfect tool to quickly find an open Internet access in the vicinity.
Tags: wifi probe, wifi probe apk, auto connect to a prefered wireless, wifi password detect, wifi probe von florian fetz apk, wifi probes, wifi, open wifi scanner.apk, que es wifi probe, preferred wifi.
- Fix ignoring silent ring tones
(59 stars)
Why do we have to manually connect to each "open" wifi network just to discover that it doesn't actually give you access until it takes you to a web page to log in with a password? This app solves that problem by checking them all for you and indicating which ones need a login. You don't necessarily have to use the "scan in background" or "auto probe" feature (I haven't tried them yet). When ev
(59 stars)
This app is the only one I've found which gives me exactly the function I want without unnecessary access rights. It simply searches all wifi Hotspots and checks automatically if there is "real" Internet access. It alerts and connects automatically if a true free wifi is found. What else you need? I hope the dev keeps the app updated further. I would also pay/donate for the app. Thanks for a easy
(59 stars)
Sadly the "Auto probe" and "Auto connect" doesn't work. Not as useful without these features...
(59 stars)
The app could scan always the status of all free sites connectivity automatically without the use of the magnifier nor ? icons. Add to that a way to connect to secure sites through this app. then you have an All in One super sweet excellent wifi connectivity app. too. Hopefully the maker of this app will make the changes. B-)


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India, despite leading by two sets, lowered its guard at a crucial stage and lost 2-3 to Spain in the FIVB World junior volleyball championship at Rio de Janeiro on Wednesday.
The 25-21, 25-17, 21-25, 12-25, 17-19 loss saw India, the World No. 7, finish eighth in the championship.
Wing spiker T.D. Ravikumar (21 points), Dhanabalan Selvaprabhu (17) and Kataryia Lavmeet (16) were the leading scorers for India.
Keywords: FIVB World junior volleyball
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