text:
In New Report, Boards Voice Concerns Over Risks
Report: "Concerns About Risks Confronting Boards" provides perspectives from public, private, not-for-profit and private equity-owned company boards. ...Read more ›
Report: "Concerns About Risks Confronting Boards" provides perspectives from public, private, not-for-profit and private equity-owned company boards. ...Read more ›
Thirty-five percent of chief financial officers (CFOs) said they find that working efficiently comes from taking greater advantage of technology; another 35 percent said delegating more responsibilities is the secret to maximizing work hours. ...Read more ›
UVa Miller Center's Milstein Commission has released a report on creating manufacturing Jobs; report is first in a series on restoring middle-class jobs. ...Read more ›
The manufacturers in the U.S. are investing more in smart meters and smart grids to provide an excellent foundation for smart city programs. ...Read more ›
New Resilience Index is the only online, interactive tool to display data on country-by-country susceptibility to supply chain risk. ...Read more ›
Nearly one-quarter of respondents of new TD Bank Environmental Attitudes Survey said they would refuse a job if they disagreed with the organization's sustainable impact. ...Read more ›
Thumbtack.com surveyed 12,632 small businesses across the United States. The survey asked questions about the friendliness of states and cities toward small businesses. ...Read more ›
Largest institutions most likely to consider climate change, resource scarcity and social responsibility in their investment strategies, according to new data from PwC's Investor Resource Institute ...Read more ›
Job security and economic outlook within the manufacturing and logistics sectors on the upswing according to a recent survey from Randstad. ...Read more ›
In the Crowe Horwath LLP and Governing Institute study, government leaders revealed that the lack of modern technology and processes creates problems, such as uncoordinated strategies among departments and untracked or incorrectly tracked data. ...Read more ›
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All Items > Knives > Spring Assisted Knives > Under $15
Black Karambit Red Accent Spring Assisted Knife - Black Plain
- Overall Length:7.25"
- Blade Length:2.625"
- Cutting Edge:2.50"
- Blade Thickness:0.12"
- Blade Material:440
- Blade Style:Hawkbill
- Blade Grind:Hollow
- Finish:Black
- Edge Type:Plain
- Handle Length:4.625"
- Handle Thickness:0.52"
- Handle Material:Aluminum
- Color:Black
- Frame/Liner:Stainless Steel
- Weight:4.98 oz.
- User:Right Hand
- Pocket Clip:Tip-Down
- Knife Type:Spring Assisted
- Opener:Thumb Stud
- Lock Type:Liner Lock
- Brand:Azan
- Model:Karambit
- Country of Origin:China
- Best Use:Everyday Carry
- Product Type:Knife
The Rancid Spring Assisted Knife from Azan is a perfect EDC (everyday carry) addition. The Rancid features 440 stainless steel black-finish hawkbill blade, jimping along the thumb rest, ambidextrous thumb studs, flipper, finger ring, secure liner lock construction, black aluminum scales & red accents, and a tip-down carry pocket clip.
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The FRB repealed its several regulations including Regulation DD, Truth in Savings and, Regulation P, Privacy of Consumer Financial Information. The Dodd-Frank Act granted rulemaking authority for a number of consumer financial protection laws to the CFPB. The CFPB adopted interim final rules substantially similar to the FRB's Regulation DD and Regulation P, and as a result, the FRB repealed its Regulation DD and Regulation P.
In conjunction with the repeal of Regulations DD and P, the FRB also issued final amendments to its Identity Theft Red Flags rule in Regulation V, the implementing regulation for the Fair Credit Reporting Act. The Identity Theft Red Flags rule requires financial institutions and creditors to adopt identity theft prevention programs. The amendments to the rule amend the definition of "creditor" and updates a cross-reference in Supplement A to Appendix J to reflect a transfer of rulemaking authority to the CFPB. In particular, the amendments clarify in amending the definition of "creditor" and in connection with certain amendments to the Fair Credit Reporting Act, that the Red Flags rule only applies to creditors that regularly extend credit or obtain consumer reports in the ordinary course of their business to reflect a transfer of rulemaking authority to the CFPB. The Identity Theft Red Flags rule, however, still applies to all financial institutions whether they meet the revised definition of "creditor."
The repeal of Regulation DD and Regulation P and the amendment to the Identity Theft Red Flags rule become effective on June 30, 2014.
IRS Circular 230 Disclosure: To ensure compliance with requirements imposed by the IRS, we inform you that any U.S. tax advice contained in this informational piece (including any attachments) is not intended or written to be used, and may not be used, for the purpose of (i) avoiding penalties under the Internal Revenue Code or (ii) promoting, marketing or recommending to another party any transaction or matter addressed herein.
DISCLAIMER: Because of the generality of this update, the information provided herein may not be applicable in all situations and should not be acted upon without specific legal advice based on particular situations.
© Goodwin Procter LLP
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2005 BEST Restaurant, General Excellence, Martha's Vineyard
Unlike at many other fine-dining destinations, there is nothing stuffy about the elegant, open-air space at Alchemy. The two-story restaurant's white tablecloths, warm atmosphere, and welcoming staff beckon diners off the street. The menu and food are superb, with French-inspired choices such as grilled tuna niáoise, roasted free-range chicken Grenoble, and the must-have risotto fritters.
Be respectful of our online community and contribute to an engaging conversation. We reserve the right to remove impersonators or personal attacks, threats, profanity, or flat-out offensive comments. By posting here, you are permitting Boston magazine and Metro Corp. to edit and republish your comment in all media.


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What makes some types of cancer resistant to drugs? Reporting in Nature, researchers write that cancer cells may be dodging treatment with help from seemingly innocent bystanders. Cancer researcher Todd Golub discusses how a tumor's microenvironment may affect its behavior.


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I liked the combination of Yum and spaghetti, love their creamy mushroom soup, and the chickenjoy is the best.
Mainly a chicken place, they also have burgers and a better selection of fountain drinks than you normally find (as if fast food joints were "normal" in the Philippines!) Competition for McDonald's, and about as good.
It's hard to avoid eating at least once or twice in a Jollibee restaurant-- especially if you are with local friends and thier families-- it is the Fast Food Favorite.
Actually the choices aren't bad-- burgers, chicken, some reasonable combos etc, and you can find one on evey corner-- open for breakfast and some are 24 hours, so be sure...
Jollibee is a local favorite.. much like McDonalds in the USA.. but obviously a regional twist to the menu.. items like Macaroni soup.. which was a favorite with the kids.. inexpensive and quick.. plus for those not used to the climate nice chilly air-conditioning to help you relax before getting back out on your adventure.
A great localized alternative to the "dreaded" McDonalds meals. Try the spaghetti, even if you don't like spaghetti. They make it sweet here (which is why the kids love it), but its actually quite good. Try the chicken as well, better than average (in deep fried terms anyway).
if your filipino taste buds crave - then satisfy yourself in Jollibee. from the yummy burgers, crispy-lecious and juicy chickens to the sweet filipino spaghetti --and to have in minutes, then this place is for you!
best fried chicken and spaghetti and french fries... ambiance os quiet relaxing and child friendly and seniors too... also love their sprite float with different colors and taste.. such delicious fast food chain... :)
The Jollibee close to Kabayan hotel / Gran prix Pasay is like any average Jollibee. The good part is that it is open 24 hours.
Only place I've ever seen a "Jollibee" fast food place was in the Philippines. It was kind of like going to KFC. Experience was enjoyable. More locals there and less of being a tourist attraction made this place a neat experience.
Proudly Filipino, this chain of stores are fast rivalling Mcdonald's especially for the filipino community around the world. The crew often gets your orders mixed up and they usually run out of food so be prepared to have a second order. Dining areas are messy and usually have children running unchecked all the time.The burger is mushy but in accordance...
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Its true that YouTube is and will be one of the best innovations in social media —an innovation that has come to define itself as a social media since 2005 and almost 9 years later it is still being used as an important informational, educational, entertainment and social medium.
YouTube has created a service for people that not only connects us virtually to one another irrespective of what part of the world we live in but also makes us realize that its a small world after all. People come forward and share their ideas, opinions, reviews and emotions in a video which is put up on display for the whole world to see.
Many people use YouTube as a platform for various purposes with the main aim of earning some recognition and entertaining those who watch them showcase their talents, emotions and ideas. They create videos and post them on a daily basis for their subscribers and viewers and hold sessions where people can interact with them. These YouTubers eventually become so popular that they are treated as celebrities on YouTube.
It is their talent and creativity that helps them earn views on their videos. Higher the number of views, the more viral or popular the video and their creators get.
There are numerous channels and videos that have gained a lot of recognition worldwide.
Here are 5 YouTube channels that you must subscribe to :
1. Nigahiga (Ryan Higa)
Ryan Higa popularly recognised by his YouTube username "Nigahiga" and his signature phrase "Teehee" at the end of his videos is an American YouTube celebrity, actor and comedian. He's known for his humorous, creative and sarcastic vlogs and videos which have been viewed over 2 million times. Higa's videos are either solo efforts or videos featuring YouTube users. As of 2014, Higa's YouTube channel, Nigahiga, has over 12 million subscribers and is one of the most subscribed channels on YouTube. According to Ryan Higa, his channel name is a combination of "Niga", which means "rant" in Japanese, and his last name, "Higa". He created a second channel, under the name HigaTV, in 2011, where he posts video blogs and behind the scenes movies and currently has over 2.1 million subscribers.
2. Equals Three (Ray William Johnson)
Another American video blogger, producer, and actor is Ray William Johnson who is best known for his YouTube series "Equals Three", in which he provides his reviews, remarks and commentary on abstract viral videos. Many of the videos that Johnson has featured on Equals Three have gained views to such an extent that the videos have received an additional boost of popularity. As of 2014, Johnson's videos have accumulated more than two billion views and 10 million subscribers. Although Johnson in his last video titled "THANK YOU FOR EVERYTHING" announced his retirement from equals three, but due to the overwhelming support from his fans and subscribers he has mentioned that he will be taking a month or two in order to cast a new host in his replacement to keep the show going.
Apart from featuring famous American actors and icons in his videos, Johnson has also released a 5-part web series titled "Riley Rewind", which he directed and starred in.
Equals Three is on one of the most subscribed channels on YouTube,and also has been recognised by Guinness World Records for the most YouTube subscribers.
3. JennaMarbles (Jenna N. Mourey)
Jenna N. Mourey, commonly known by her stage name Jenna Marbles, is a famous YouTube personality and lives with her two dogs, Mr. Marbles and Kermit seen in most of her videos. Some of Marbles' popular videos that helped her gain recognition include "How To Trick People Into Thinking You're Good Looking" (Currently having over 57 Million views) and "How To Avoid Talking To People You Don't Want To Talk To" (Over 33 Million views). Being a comedian and vlogger Marbles has uploaded videos that have sum up to an approximate total of 1 Billion views and more than 13 Million subscribers.
4. Jus Reign (Jasmeet Singh)
Jus Reign, known as Jasmeet Singh, is a Canadian, Punjabi comedian who has attracted many young YouTube subscribers and viewers with his humorous parodies, vlogs, and Monologues. Being a part of a growing number of talented artists such as ||Superwoman||(Lilly Singh) and more who use YouTube as a platform made available on the internet to showcase their art to the world. Jasmeet's channel has grown into one of the highest subscribed channels on the video platform presenting him with promising opportunities. This young YouTuber is certainly a rising talent to watch out for.
5. IISuperwomanII (Lilly Singh)
Lilly Singh is undoubtedly one of the most famous YouTube celebrities popularly known as"IISuperwomanII". A Canadian stand up-comedian & vlogger of Indian descent, Lilly has earned more than 260 combined million views and over 3 million subscribers on her channel. She not only has a vibrant fan following on YouTube, but also on Facebook and Twitter. Her vlogs consist of comedy sketch videos about various topics; From shopping at the mall to superstitions to being single. Her work is influenced by her Indian heritage, which she takes great pride in. She often features characters inspired by her Punjabi parents.
Being a comedian and a motivational speaker, she seeks to entertain and uplift people which not just includes her fans from India but from all over the world.


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Body fluid sampling device comprising a skin-piercing element (10) having a fluid pathway (11) for receiving body fluid, at least a portion of said fluid pathway is open to the environment and further comprising a fluid receiving means (40) being spaced from said fluid pathway so that fluid in said pathway will not contact the fluid receiving means initially. Said fluid receiving means may have a test zone (45) for performing an analytical reaction. Fluid from said channel is contacted with said fluid receiving means either by bringing the fluid receiving means and the fluid into mechanical contact or by electrically transporting fluid from the channel onto the fluid receiving means.
1. Device for sampling body fluid comprising
a fluid pathway (11) for receiving body fluid in a first state, wherein at least a portion of said fluid pathway (11) along its longitudinal extension is open to the environment and
a fluid receiving means (40) being separately spaced apart from said fluid pathway (11) so that body fluid in said pathway (11) is out of fluidic contact with the fluid receiving means (40) in the first separated state,
the device being adapted to undergo a physical change upon actuation so as to assume a second contacting state in which a fluid in said fluid pathway (11) contacts said fluid receiving means (40),
wherein said device having a moveable portion (13) which can be moved and at least a portion of said fluid pathway (11) or fluid receiving means (40) is located on said moveable portion (13) to assume the contacting state.
2. Device for sampling body fluid comprising
a fluid pathway (11) for receiving body fluid in a first state, wherein at least a portion of said fluid pathway (11) along its longitudinal extension is open to the environment and
a fluid receiving means (40) being separately spaced apart from said fluid pathway (11) by an air gap (92) so that body fluid in said pathway (11) is out of fluidic contact with the fluid receiving means (40) in the first separated state,
the device being adapted to undergo a physical change upon actuation so as to assume a second contacting state in which a fluid in said fluid pathway (11) contacts said fluid receiving means (40),
wherein body fluid received in said fluid pathway (11) is moved by electrical actuation onto the fluid receiving means (40).
3. Device according to
4. Device according to
5. Device according to
6. Device according to
7. Device according to
8. Device according to
9. Device according to
10. Device according to
11. Device according to
12. Device according to
13. Device according to
14. Device according to
15. Device according to
16. Device according to
17. Device according to
18. Device according to
19. Device according to
20. Device for sampling body fluid comprising a skin piercing element (10) with a capillary channel as a laterally open fluid pathway (11) for receiving body fluid, wherein the channel has a sampling section (100) and at least one discharge section (102) located downstream the sampling section (100) and/or branching off upstream the sampling section (100) for receiving and discharging a fraction of the body fluid entering the capillary first, and wherein the sampling section (100) is a test zone (45) or is contacted with a test zone (45) for analysis of body fluid contained therein.
21. Device according to
22. Device according to
23. Device according to
24. Device according to
25. Device according to
26. Device for body fluid analysis comprising
a skin piercing element (10) with a fluid pathway (11) for receiving body fluid, wherein at least a portion of said fluid pathway (11) is open to the environment and
a fluid receiving means (40) being spaced from said fluid pathway (11) so that fluid in said pathway is out of fluidic contact with the fluid receiving means (40),
said fluid receiving means (40) comprising a test zone (45).
27. Device according to
28. Device according to
29. Device according to
30. Device according to
31. Device according to
32. Device according to
33. Device according to
34. Device according to
35. Device according to
36. Device according to
37. Device according to
38. Device according to
39. Device according to
40. Device according to
41. Device according to
42. Device according to
43. Method for determining an analyte concentration in body fluid comprising the steps of:
a) receiving body fluid in a fluid pathway (11) preferably of a skin piercing element (10), the fluid pathway (11) being spatially separated from a fluid receiving means (40) during filling,
b) contacting the fluid pathway (11) with the fluid receiving means (40) so that body fluid from the fluid pathway (11) contacts the fluid receiving means (40) and reaches a test zone (45),
c) receiving signals from said test zone (45) which are characteristic for an analyte concentration,
d) processing said signals to determine the analyte concentration.
44. Method according to
45. Method according to
46. Method according to
47. Analytical device comprising
a support structure having a channel (11) therein which is accessible from the surrounding in at least an access region, said channel having a fluid introduction region (a) as well as a discharge region (d) located downstream the access region
a fluid receiving means (40),
the fluid receiving means (40) being spaced from the channel in a first state and the fluid receiving means (40) being in contact with fluid located in the access region in a second state to receive fluid, so that the fluid receiving means (40) is not contacted with a fluid from the discharge region.
48. Method of sampling fluid comprising the steps of
introducing fluid into an introduction region of a support structure which has a channel therein, said fluid filling an access region of the support structure which is accessible from the surrounding and having a waste region (114) located downstream the access region
contacting a fluid receiving means (40) with fluid located in the access region to receive fluid but not with a fluid portion in the discharge region.
49. Analytical device comprising
a support structure having a channel for receiving fluid therein which is accessible from the surrounding in at least an access region,
a fluid receiving means (40) being spaced from the channel
a source of electrical potential which when turned on applies an electrical potential between fluid in said access region and said fluid receiving means (40) so that fluid from said access region is transported onto said fluid receiving means (40).
50. Analytical device according to
51. Analytical device according to
52. Method for transporting fluid from a support structure to a fluid receiving means (40), comprising the steps of
holding a support structure having a channel for receiving fluid therein which is accessible from the surrounding in at least an access region in a spaced relationship to a fluid receiving means (40),
applying an electrical potential between fluid in said access region and said fluid receiving means (40) so that fluid from said access region is transported onto said fluid receiving means (40).
53. System for body fluid analysis comprising
a skin-piercing element with a fluid pathway (11) for receiving body fluid, wherein at least a portion of said fluid pathway (11) is open to the environment and
a fluid receiving means (40) being spaced from said fluid pathway (11) so that fluid in said pathway will not contact the fluid receiving means (40), said fluid receiving means (40) comprising a test zone (45),
a transport means to transport the skin piercing element (10) into contact with the fluid receiving means (40).
54. System according to
a magazine storing multiple fluid receiving means (40).
55. System according to
This application is a continuation of International Application No. PCT/EP2005/002273 filed Mar. 4, 2005, published on Sep. 15, 2005 as WO 2005/084530 A2, which is incorporated by reference in its entirety.
The present invention relates to the field of body fluid analyses in order to make a diagnosis or to monitor the concentration of analytes such as the blood glucose concentration.
The invention concerns a device or system for sampling small amounts of body fluid. A body fluid sampling device may comprise a skin piercing element with a fluid pathway for receiving body fluid therein. At least a portion of the fluid pathway is open to the environment. The sampling device further comprises a fluid receiving means which is separated from the fluid pathway so that fluid in the pathway will not contact the fluid receiving means in a first (separated) state. The device or system can be brought into a second state in which at least a portion of the pathway contacts the fluid receiving means so that fluid is transferred. Based on signals from a sensor of the fluid receiving means analyte concentration can be determined.
Systems for sampling body fluids are already known in the prior art in which body fluid is taken up into a disposable element. Blood collection and analytical systems are e.g. known from the document EP 0 199 484 which comprise a disposable unit with a capillary to collect body fluid and to transport the body fluid into a detection area. The further development of this concept is described in WO 97/42888. The arrangement described in this patent is particularly suitable for collecting relatively small amounts of body fluids which is primarily accomplished by pressing a ring onto the area surrounding a collection site and a pump movement. A system for analysis based on small amounts of interstitial fluid is known from EP 0 723 418. For this purpose a very thin closed hollow needle is inserted into the dermis and interstitial fluid is conveyed through the needle to a test zone by applying pressure to the area surrounding the puncture site. A highly miniaturized arrangement which also utilizes a closed needle to withdraw body fluid is known from U.S. Pat. No. 5,801,057. A particular advantage of this arrangement is the extremely thin needle which can be inserted into the arm region of a patient without essentially any pain.
Whereas the arrangement described in U.S. Pat. No. 5,801,057 already fulfils numerous practical requirements, some features are in need of improvement. A general problem with the sampling devices according to the previously mentioned document is to manufacture the hollow needle cost-effectively and as small as possible.
With this aim body fluid samplers which have an open fluid pathway structure are contemplated. The documents US 2003/0018282 and US 2003/0028125 both describe skin piercing devices which have an open channel for body fluid sampling which at least partially is located in a region of a piercing needle. Body fluid sampled into the fluid pathway is transferred to a testing zone which is fixed to the skin piercing element. In particular US 2003/0028125 describes that the skin piercing element is integral with a part of a test strip. A further document that contemplates a similar sampling and testing device with provision of a pooling area is described in US 2002/0168290.
The prior art sampling and testing devices describe embodiments where sample from a capillary channel is directly transferred to a testing zone which is in contact with the channel. Contrary to that the present invention proposes body fluid sampling and testing devices where the fluid pathway in a phase in which sample is taken up is out of fluidic contact with a testing zone. After having taken up a fluid sample into the fluid pathway at least a portion of the fluid pathway is being contacted with a fluid receiving means that receives fluid from the pathway. The fluid receiving means may be a test zone or it may be a zone that transports sample to a test zone. Wetting of the test zone therefore can be initiated in a controlled manner by the contacting step. This triggering of test zone wetting has the advantage that the reaction time (i.e. the time between contacting a test chemistry with sample fluid and reading of test results) can be controlled which leads to higher accuracy of analyte determination. A further advantage compared to the prior art sampling devices is that fluid sampling and contacting of the sampling device with a testing zone can be conducted at different locations. Fluid sampling for example can be done at the front end of a hand-held apparatus while contacting with a testing zone can be made within the apparatus. Due to this shuttle function of the skin piercing element optics or other evaluation means can be moved into the interior of a housing which is advantageous with view to the limited space at the front end. A further advantage of contacting the test zone or the fluid receiving means with sample already present in the fluid pathway is that contact can be made with a portion of the fluid pathway that does not contain the first fluid emerging the body. By this influences of plasma and substances from the body surface can be avoided or reduced.
Furthermore a physical separation of the test zone from blood during the sampling step avoids that test chemistry diffuses into the human body during sampling.
The present invention therefore has significant advantages over the fluid sampling devices of the prior art.
One particular field of application of systems and devices for withdrawing small amounts of body fluid is the so-called spot-monitoring in which the concentration of particular analytes present in body fluids is determined at a particular time. Such measurements can be carried out repeatedly at time intervals in order to monitor a change of analyte concentration. Such analysis employing disposable test elements has proven to be particularly advantageous especially in the field of blood sugar measurement by diabetics. If excessively high blood sugar values (hyperglycaemia) occur in a diabetic over a period of time, this can lead to serious long-term damage such as blindness and gangrene. If, on the other hand, a diabetic gets into a state of hypoglycaemia because he has for example injected too large a dose of insuline, this can become life-threatening if the diabetic falls into a so-called hypoglycaemic shock. A regular control of the blood sugar level enables the diabetic to avoid hyperglycaemic and hypoglycaemic states and also to learn how to coordinate his eating habits, bodily activity and insuline medication. In addition to improving and maintaining the health of diabetics, regular blood sugar monitoring also has considerable overall economic advantages since high costs for secondary diseases can be avoided. The reasons which prevent a more widespread and consequent use of blood sugar monitoring are primarily the pain caused by the required body fluid collection and the multiple handling steps of systems currently in the market. With the currently used systems the diabetic or medical staff must firstly obtain a drop of blood which is usually obtained from the finger pad. So-called lancing devices may be used to reduce pain. A lancing device must be firstly loaded with a lancet, tensioned, placed on the body surface and triggered. After the lancing process the user has to milk his finger in order to convey a drop of blood out of the puncture wound. Before this procedure the diabetic has to already place a test strip in a blood sugar measuring instrument and activate it. The drop of blood can now be applied to the test strip and after for example 10 seconds a blood sugar measurement is available. Finally the user has to dispose of the spent lancet and test strip. The present invention enables the process of blood sugar measurement to be greatly simplified.
Simplification is reached by employing a piercing element which receives body fluid in a fluid pathway and this fluid then can be automatically contacted with a fluid receiving means including a test zone. A simplification of blood glucose testing not only is advantageous for current users, it hopefully also has the effect that more people having diabetes will test their blood glucose concentration on a regular basis.
A sampling device and system according to the present invention serves to withdraw small amounts of body fluid. In this context body fluids are understood in particular as blood, interstitial fluid and mixtures of these body fluids. Whereas in conventional blood collection systems this is usually carried out on the finger pad, the collection system according to the invention can also be used to withdraw blood from alternate sites on the body such as the forearm and the palm.
A skin piercing element for withdrawing small amounts of body fluid according to the present invention has a protruding portion with a sharpened end for piercing skin. Within at least a region of the protruding portion a fluid pathway is located which has a capillary activity to transport body fluid. At least a part of the capillary structure, preferably the whole capillary, is open to the outside along its extension. A capillary structure is understood within the scope of the invention as a body which transports body fluid as a result of capillary forces towards the proximal end of the capillary structure when the distal area is contacted with body fluid. With regard to this function the capillary structure according to the invention is similar to the open needle structures described in US 2003/0018282 and US 2003/0028125 to which reference is made herewith. However, an important difference is that these documents describe microneedles where the capillary channel is steadily in fluidic contact with a test zone so that body fluid received in the capillary channel is directly applied to the test zone and hence initiates reaction.
The longitudinal extension of the skin piercing element extends from a proximal end which provides a holding area to a distal end having a protruding portion which is intended to be inserted into the skin. The hollow needles of the prior art have an opening at their distal end through which body fluid can enter and the fluid pathway then changes into a closed channel or chamber in which the test zone is located. In contrast the capillary structure according to the present invention preferably is open to the outside over its entire longitudinal extension and the fluid path is not closed by a test zone.
Open capillaries can be manufactured by photolithographic methods like those described in the document U.S. Pat. No. 5,801,057 and which are known from the field of semiconductor technology. It is also possible to provide channels, grooves etc. which are open to the outside in solid needles by milling, etching and such like. Such depressions which provide the capillary channel may lead from the tip or at least from a region adjoining the tip of the skin piercing element to a proximal holding region which is connectable to a holding device. The depressions or capillaries do not necessarily have to run in straight lines, but can also for example be arranged in spirals, meanders etc. Furthermore the capillaries may be arranged in a network with bifurcations, split capillaries, etc. The cross-section of the capillaries can for example be V-shaped, semi-circular or also rectangular.
Such channels are preferably generated by etching processes as photochemical milling (PCM). PCM is the machining of metal structures without heating or mechanically milling the starting material. PCM is based on optical pattern transfer and etch processes. It is known to be a micromachining technology.
The starting materials are metal sheets. There is a wide range of different materials to choose from, ranging from medical steel to aluminium and invar. In the case of steel, most of the standard medical types are available. When compared to silicon, glass or quartz, the cost of the raw material steel is much lower.
PCM is a Photolithography based fabrication method, i.e. the outline of a structure to be machined is transferred optically. A photosensible polymer is applied onto the metal sheet in a film. The polymer is referred to as photoresist and comes in two types:
1. Dry resist (foil laminated onto the substrate)
2. Wet resist (liquid spread and cured on the substrate)
Upon selective illumination of the photoresist via a shadow mask, the photoresist can be selectively removed from the substrate (which is often referred to as patterning).
When the patterned substrate is exposed to aqueous solution (e.g. Iron (III) chloride for steel) which reacts with the substrate material, the material is selectively removed from the areas where there is no photoresist left (referred to as the "etch"). There are two main principles of how the substrate can be brought in contact with the substrate.
1. dipping of the substrate into a bath of etchant
2. spraying of the etchant on the substrate
The etch step is in its nature generally isotropic, i.e. the etch rate is approximately the same in all directions. Isotropicity can be influenced by a large number of parameters during the photolithography and during the etch, thus it is possible to control the etch profile within certain limits.
Spray etching offers larger flexibility in controlling etch rates and profiles when compared to dip etching.
In most cases, it is imperative that the photoresist layer is removed from the substrate to obtain the sampling devices. Removal of photoresist layer is normally a wet process.
In addition to the already mentioned methods for incorporating capillary channels into surfaces, it is also possible to generate the capillary channels by assembling bodies in a way that capillary gaps are created. Thus it is for example possible to fasten two or more solid needles together for example by welding such that the contact areas of the solid needles form capillary channels. In a corresponding manner it is also possible to twist wires together in the form of a stranded wire such that numerous contact areas are formed which generate the capillary channels. Further skin-piercing elements with fluid pathways can be created by applying one or more layer of materials (e.g. laminated foils) onto a flat needle in a way that a capillary gap is created between the layers or is provided in one such layer.
The capillary channels which provide the fluid pathway typically have a greater depth than width. The ratio of depth to width (generally referred to as aspect ratio) is preferably 0.3 to 3. The cross-section of the capillary channel is typically larger than 2500 μm2 and less than 1 mm2. Preferably the capillary channel has a width in the range of 50 to 450 micrometers, most preferred around 200 micrometers. As already stated above it is advantageous that the capillary channels are open to the outside such that they can take up body fluid while the capillary structure is inserted into the body. In order to achieve a good uptake of body fluid the area of the capillary structure that is open to the outside should have a length of 0.5 mm or more.
The shape of the skin piercing element is relatively uncritical. It can for example be in the form of a small cube. Special measures are usually not necessary to mount the skin piercing element in a drive unit but a holding region located at the proximal end of the skin piercing element is preferred. Advantageously the holding area is formed integral with the other regions of the skin piercing element. Piercing element designs can be employed that are known for disposable lancets of conventional blood sampling systems. For example the holding region can have tapers into which spring elements of a holder of a drive unit engage in order to hold the piercing element. The piercing element is advantageously positioned within a holder in such a manner (for example by pressing the end of the piercing element facing away from the tip against a stop) that it allows a good control of the piercing depth. Reference is made to the document EP B 0 565 970 with regard to such a holder and the interaction between the holder and the disposable lancing unit.
The body fluid sampling device in addition to the skin piercing element has a fluid receiving means which is spatially separated from the fluid pathway of the skin piercing element so that fluid in that pathway will not contact the fluid receiving means during filling. The fluid receiving means and the pathway, however, are contacted to each other after fluid sample has been received in at least a part of the fluid pathway and when start of the analytical reaction is desired.
The spatial separation of skin piercing element and fluid receiving means enables embodiments where the skin piercing elements is employed as a shuttle to transport sampled fluid to a fluid receiving means. This is particularly advantageous when fluid sampling is made in a spatially restricted area (e.g. the front end of apparatus) and the fluid receiving means does not fit well into this limited space. The latter in particular is the case for fluid receiving means fixed to a tape as e.g. described in European patent application 0 202 6242.4, U.S. Pat. No. 4,218,421 and EP 0 299 517. The shuttle function enables a testing process with the steps of
When a magazine with fluid receiving means is employed there further can be the steps of exposing a specific fluid receiving means from the stored fluid receiving means to contact the skin piercing element loaded with sample fluid. When the specific fluid receiving means has been evaluated a further fluid receiving means can be exposed to contact sample fluid on a skin piercing element.
A system according to above shuttle concept therefore has one or more skin piercing elements, a drive for driving a skin piercing element to pierce skin, a transport means to transport the skin piercing means into contact with a fluid receiving means. The drive for piercing and the transport means may be employed in the same drive unit. Further the system may comprise a storage unit for multiple fluid receiving means. The system further may comprise an exposing unit for successively exposing fluid receiving means to receive fluid.
The fluid receiving means is a structure that can take up fluid from a fluid pathway of the skin piercing element. This uptake of fluid e.g. can be accomplished by an electrical potential applied between fluid in the fluid pathway and the fluid receiving means. Preferably, however, the fluid receiving means has a higher capillarity than the fluid pathway of the skin piercing element so that during contact fluid is automatically taken up. In this regard the fluid receiving means can be made from a fleece or fabric material that has a high capillarity and is hydrophilic (at least in areas for fluid take-up). The fluid receiving means may have a particular region which comprises such material of high capillarity or the whole area of the fluid receiving means can act as receiving means for fluid from the fluid channel. The fluid receiving means may be a test zone in itself which can be covered with a fabric or woven material or the fluid receiving means may be more complex and allows for pre-processing of sample fluid and/or transport of fluid to a sensor/test zone. Pre-processing may comprise filtration of fluid sample and/or a mixing with reagents.
The fluid receiving means comprises a test zone with at least one chemistry layer that contains a reagent for detecting an analyte.
The reagent undergoes a detectable change due to reaction with the analyte to be detected. Typical reagents for detecting glucose are based for example on glucose oxidase in conjunction with a chromogenic redox system. Reagents are well known in the prior art for optical evaluation which form a colour with glucose from the body fluid. Furthermore reagents are also known from the field of blood sugar test strips which allow electrochemical detection of analytes. The reagent mixtures that are used are usually in a solid state and, due to their constituents (e.g. aluminium oxide, kieselguhr and such like), have such a high capillarity that they can take up body fluid from the capillary channel. Since these detection systems are well-known from the prior art they are not described in more detail herein but reference is made to U.S. Pat. No. 5,762,770 and U.S. Pat. No. 36,268.
The body fluid collection system according to the present invention additionally has a drive unit which, when activated, moves the skin piercing element from a first into a second position such that it performs a lancing movement. Suitable drive units are well-known from the field of blood sampling systems. It can for example contain a spring which is cocked by the user and when released drives the skin piercing element. A particularly advantageous drive unit is described in EP B 0 565 970.
Systems/devices for body fluids analysis comprise a detection unit. If a sensor/test zone containing reagent is used which changes colour or forms a colour when an analyte is present, the system can have an optical detection unit comprising a light source and a detector to detect transmitted or reflected light. When electrochemical detection is employed, the system has electrodes which contact the test zone or the fluid receiving means. For evaluation of raw signals the system can have electronic devices known in the prior art in order to determine the concentration of analyte for example by measuring the so-called Cotrell current (see e. g. U.S. Pat. No. 36,268).
With the skin piercing element according to the present invention body fluid can be withdrawn while the protruding portion is inserted into the skin (i.e. withdrawal of sample directly from the body and/or from body fluid emerging on the body surface) or the protruding portion can be retracted from the body after piercing and takes up body fluid that emerges on the body surface. A partial withdrawal in which the protruding portion remains in the body but the lancing channel in the skin is opened to collect body fluid is especially suitable for sampling at the arm. This is due to the fact that small incisions on the arm close very rapidly such that no fluid or only very small amounts of fluid emerge after piercing. On the other hand the sensitivity to pain is much less pronounced on the arm as compared for example to the finger and thus when the protruding portion remains in the body this is not felt to be painful. As described above an advantage of a capillary structure that is open to the outside is that fluid can be taken up through the open fluid channel whereas the area for taking up liquids by hollow needles is limited to the front end of the needle. The latter is particularly disadvantageous when the needle opening becomes sealed by tissue (due to a stamped out tissue portion) during the piercing process such that no liquid or only an inadequate amount can be taken up.
Furthermore a withdrawal process can be carried out with the sampling device according to the invention which is a combination of the previously mentioned processes. In this combined process piercing is carried out firstly, the protruding portion is pulled back over a part of the piercing path and is allowed to reside there for a collection period of few seconds. An advantage of this process is that the retraction of the protruding portion exposes a part of the lancing channel such that body fluid collects therein and can enter from there into the fluid pathway of the skin piercing element. Further such withdrawal process has the advantage that blood on the skin surface can be taken up by the open channel. Depending on the circumstances it may even be possible to remove residual blood almost completely so that no blood is seen by the user.
A further decisive factor which is important for an efficient uptake of body fluid into the fluid pathway is the wettability of the capillary channel. When capillary structures made of silicon are used, these are usually adequately wettable due to a silicon oxide layer on the surface. If metals are used for the capillary structure, these are often relatively difficult to wet. This can be counteracted by a number of different measures such as silication of the surface. The wettability is usually adequate when the liquid in the capillaries has a concave meniscus which is the case when the wetting angle is less than 90�.
The present invention will be described in more detail with regard to the figures, in which:
FIGS. 11 to 14 show top views of channel designs for additional fluid discharge.
For the purpose of promoting an understanding of the principles of the invention, reference will now be made to the embodiments illustrated in the drawings and specific language will be used to describe the same. It will nevertheless be understood that no limitation of the scope of the invention is thereby intended. Any alterations and further modifications in the described embodiments, and any further applications of the principles of the invention as described herein are contemplated as would normally occur to one skilled in the art to which the invention relates.
As can be seen from
A first advantage over the prior art is that measurement can be initiated at a specific point in time. This means that the time between wetting of the test zone and measurement of the final signal can be chosen at will. The time period, however, is shorter than the drying time of blood in the capillary. Knowing or controlling the time of reaction improves accuracy of the measurement. Further a signal can be measured beginning directly after wetting which allows to monitor reaction kinetics. Evaluation of this early signals can be used to improve accuracy of the measurement result as well. A further advantage can be seen from
It has to be understood that this concept which avoids to contact the fluid receiving means with (contaminated) fluid received first in the channel can be applied to a number of device designs and is not restricted to sampling devices having a skin piercing element. This invokes a method of sampling fluid comprising the steps of
introducing fluid into an introduction region of a support structure which has a channel therein, said fluid filling an access region of the support structure which is accessible from the surrounding and the channel having a discharge region located downstream the access region
contacting a fluid receiving means with fluid located in the access region to receive fluid but not contacting it with fluid in the discharge region.
But now back to the embodiment shown in
It has to be considered, that instead of bringing the capillary to the test zone it is also possible to bring the test zone to the capillary by e. g. bending the carrier.
A skin piercing element according to
piercing skin
sampling body fluid into a portion of the capillary channel (region (a)).
contacting the capillary channel in a collecting region (b) with a test zone and/or a carrier so that region (b) fills with body fluid
detecting changes of the test zone due to reaction with analyte from the body fluid.
A magnetic field 72 provided by an electromagnet 74 (or permanent magnet, solenoid, or other suitable means) thus exerts an actuation force 70 on the sensor (or channel portion or both), bringing them into fluidic contact. The force magnitude and thus the time-dependent triggering of the fluidic contact is controlled by controlling the magnetic field strength, i.e. by switching the electro magnet 74 or approaching a permanent magnet.
Furthermore, a magnetic dipole moment may be induced in a nonmagnetic ring (or similar geometry) deposited on the sensor or channel portion by time-varying magnetic fields at the location of the ring. This represents an alternative way to produce an actuation force for triggered fluidic contact.
As shown in
As outlined above, the glucose concentration is determined by a kinetic measurement of the colour change in the sensor 45 upon wetting with a sufficiently large amount of blood contained in the pathway or channel 11. A reflectometric measurement is performed by illuminating the sensor 45 with incident light 84 of appropriate wavelengths and detection of the reflected radiation 86.
The limited detection area on the sensor 45 imposes severe constraints on the mechanical positioning tolerances of the wetted test zone with regard to the optical detection system. Furthermore, if only a small detection area is available, inhomogeneities in the sensor enzyme chemistry more severely influence the coefficient of variation for repeated glucose measurements. Simultaneous optical detection of the triggered actuation between blood and sensor 45 necessitates that there no interference between the triggering actuation mechanism and the optical detection system.
An optical system consisting of appropriate light emitter and receiver and and optics such as lenses and/or optical fibres is employed for the reflectomertric measurement. The amount of light of a certain wavelength reflected from the sensor 45 gives a measure of the glucose concentration.
The sensor 45 typically consists of an enzyme chemistry mixed with small particles providing diffuse reflection of the incoming light, deposited on a polycarbonate strip or foil 82 with well defined optical transmission properties. The irradiating light 84 is diffusely scattered by the particles in the strip, and absorbed by dyes activated by enzymatic reactions with blood glucose. Thus the amount of reflected light 86 is reduced by increased absorption with increasing glucose concentration.
The elastomeric optical element 80 has a refractive index closely matched to that of the sensor 45. The element 80 is employed as an intermediate layer or slab between the sensor 45 and the optics of the detection unit. The element 80 may have a means 88 which allow it to be used as a lever arm for the transduction of mechanical displacement for the triggered actuation of the sensor 45 (see
The aforesaid components thus:
Alternatively, as shown in
The optical waveguide/fibre bundle 94 is mechanically actuated by an actuation mechanism (a motor, or other drive unit, or a mechanism translating the microsampler movement into a displacement of the optical waveguide/fibre). The intermediate elastomeric material 80 translates the mechanical displacement of the optical fibre or other mechanical actuator directly to the sensor 45, thereby serving as a mediator for the triggered actuation/contact between the sensor 45 and the adjacent portion of the blood-filled micro fluidic channel 11.
The bundle 94 of small diameter fibres 96 is furthermore used to address small regions on the sensor 45, since the cone of acceptance of light for each single fibre 96 in the bundle is limited by its numerical aperture. A densely packed bundle of fibres thus serves to sample discrete small regions on the sensor. A few of the fibres may actually sample parts of the wetted detection area on the sensor, while other fibres sample the non-wetted parts. The bundle of fibres may be coupled to a detector array or CCD for individual readout of the fibres, thus generating an image of the detection area. Individual sampling of the fibres enables the detection in a small sensor area, while mechanical positioning tolerances are largely relaxed.
Each single fibre may either be addressed for illumination of the sensor, or for collection of the diffuse reflected light, or for simultaneous illumination and collection if an appropriate beam splitter is used. A randomized distribution of the fibres in the bundle is desirable to provide homogeneous illumination of the sensor and complete detection coverage of the sensor surface.
As shown in
While the invention has been illustrated and described in detail in the drawings and foregoing description, the same is to be considered as illustrative and not restrictive in character, it being understood that only the preferred embodiment has been shown and described and that all changes, equivalents, and modifications that come within the spirit of the inventions defined by following claims are desired to be protected.
Referenced by
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Email AddressVerified
Phone Number(▒▒▒) ▒▒▒- ▒▒ 80
Reviewed3 Reviews
Offline IDPersonal Info
- School
- Appalachian State University
- Work
- Visiting Assistant Professor
- Katie's Airbnb Symbol
Hey, I'm Katie!
I recently moved to Boone, NC from Long Island, but have lived many other places, including South Florida, Denver, Atlanta, Cincinnati and Albany (briefly). I currently work at Appalachian State University and love the perks of being a college professor, including the opportunity to travel many interesting places! I love outdoorsy stuff and yoga, as well as reading good books, watching interesting movies and cooking tasty food. And then eating it. I love food in general.
Mmmm, food.
When I travel I am rarely in the place I'm staying, because I try to do too many things in too little time. Which makes for really solid sleeping at night :) Also I am always open to recommendations for things off the beaten path; I like seeing the tourist staples, but also getting a flavor for the local area and culture.
And that's about as much as I can sum myself up in a few paragraphs... except that I also have a three-legged cat who is awesome and I would take with me everywhere if it weren't completely impractical. And also that that obviously isn't me in my profile photo (and may eventually get an angry email from the girl who runs (website hidden)) but I'm very protective of my Internet identity. Including being the last 1% of the planet not on Facebook.


text:
Love you too!
Added to Bag!
We'll let you know if it's back in stock!
Added to Wishlist!
Travel Funds Wallet
Whether you're heading to the flea market in Paris, on your way to your favorite New York eatery, or simply going to the farmers' market in your hometown, this adorable wallet will ensure that you have all the necessary provisions to make your excursion a successful one. Crafted in the shape of a a miniature suitcase, this vegan faux leather wallet boasts caramel straps and brass grommets on its chocolate exterior, along with a zip-secured pouch to store change, and a snap-shut flap for all of your cards and cash. No matter where your travels take you, so long as you have this wonderful, whimsical wallet in your handbag, you're sure to make the trip in well-organized style.
Final Sale: This item cannot be returned or exchanged.
- Shell: 100% Polyurethane. Lining: 100% Polyester.
- Measures 5.5 inches in length, 3.5 inches in height, 1.5 inches in width.
- Snap closure. Twelve interior card slots. One interior divided pocket with zipper closure. Two interior open pockets.
- Imported


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AT&T Named One of the Most Trusted Companies in Privacy
DALLAS, Feb. 25 /PRNewswire-FirstCall/ — AT&T* today announced it has been named a Most Trusted Company in Privacy by Ponemon Institute, an information security research company. AT&T ranked No. 20 in Ponemon Institute's nationwide survey of more than 99,000 U.S. adults in Q4 2009.
For the fifth consecutive year, the Ponemon Institute asked adult-aged respondents from the U.S. to list up to five companies in various industry sectors that they trusted for honoring their privacy commitments. Survey participants were asked to consider the protection of their personal information.
"We are honored to be recognized as a most trusted company in privacy," said Dorothy Attwood, AT&T senior vice president for public policy and chief privacy officer. "At AT&T, privacy commitments are fundamental to the way we do business every day, and we use powerful security safeguards to protect customer data."
In June 2009, AT&T unveiled its new, unified privacy policy, which replaced 17 separate privacy policies for various AT&T companies, products or services. The overhauled privacy policy reflects direct feedback from consumers. AT&T asked customers about privacy issues and incorporated their feedback into our privacy commitments. Before it went into effect, AT&T offered customers a 45-day preview of the updated privacy policy, answering questions, and making clarifications to policy language.
As a result, the privacy policy is easier to find – centralized at att.com/privacy, and linked from every page on att.com – and easier to read, streamlining 37,000+ words in the original policies to approximately 8,000 words. In addition, AT&T added short videos to illustrate important key concepts from the privacy policy.
"Our research shows that consumers value companies and brands they can trust," said Dr. Larry Ponemon, chairman and founder, Ponemon Institute. "Consumers told us they value companies that protect privacy and safeguard personal information. We commend AT&T for the recognition among consumers that it is a Most Trusted Company in Privacy."
For more information on the 2010 Most Trusted Companies for Privacy list, visit http://www.ponemon.org.
*AT&T products and services are provided or offered by subsidiaries and affiliates of AT&T Inc. under the AT&T brand and not by AT&T Inc.
About AT&T
AT&T Inc. (NYSE: T) is a premier communications holding company. Its subsidiaries and affiliates – AT&T operating companies – are the providers of AT&T services in the United States and around the world. With a powerful array of network resources that includes the nation's fastest 3G network, AT&T is a leading provider of wireless, Wi-Fi, high speed Internet and voice services. AT&T offers the best wireless coverage worldwide, offering the most wireless phones that work in the most countries. It also offers advanced TV services under the AT&T U-verse(SM) and AT&T |DIRECTV(SM) brands. The company's suite of IP-based business communications services is one of the most advanced in the world. In domestic markets, AT&T's Yellow Pages and YELLOWPAGES.COM organizations are known for their leadership in directory publishing and advertising sales. In 2009, AT&T again ranked No. 1 in the telecommunications industry on FORTUNE® magazine's list of the World's Most Admired Companies. Additional information about AT&T Inc. and the products and services provided by AT&T subsidiaries and affiliates is available at http://www.att.com.
© 2010 AT&T Intellectual Property. All rights reserved. 3G service not available in all areas. AT&T, the AT&T logo and all other marks contained herein are trademarks of AT&T Intellectual Property and/or AT&T affiliated companies. All other marks contained herein are the property of their respective owners.
SOURCE AT&T Inc.


text:
Tech Helproom
It's free to register, to post a question or to start / join a discussion
A couple of questions about "dongles"
Likes # 0
Posted February 4, 2013 at 3:45PM
I have 2 PC's, one running Windows 8, The other running Vista. They are in different rooms in the house. I am connected to the internet with Virgin Broadband and I have a Virgin Mini-Hub. On the Vista PC, which is 2 rooms away I cannot get the internet and have been advised by the Virgin engineer I need a "dongle". I've had a look at "dongles" on Google and I can see it's a USB connection. Fair enough I've used USB's for file transfers etc, but I take it this "dongle" is different. So my question is, bearing in mind the distance one PC is from the other, do I need a powerful "dongle". Put plainly are some "dongles" more powerful than others, and if so, how can you tell which is more powerful? Any help much appreciated.
Likes # 0
Posted February 4, 2013 at 4:19PM
The dongle the engineer referred to is a USB wireless adapter, although why he thinks that it will cure the problem I don't know. Presumably your Vista PC already has a built-in wireless network adapter, and a dongle isn't likely to be any better at connecting to your wireless router.
One of the best USB wireless adapters around is the Linksys AE1000 It's not cheap, but it out-performs pretty well everything else.
Likes # 0
Posted February 4, 2013 at 4:25PM
Thanks for the help and info.
Likes # 0
Posted February 4, 2013 at 4:27PM
Sounds more like you need a Wireless Range extender.
Likes # 0
Posted February 4, 2013 at 6:32PM
Or forget wireless and use a couple of homeplugs.
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Current Filters
Traxxas pro .15 w/pull start with long shaft is a long crankshaft Version of the Traxxas Pro TRX-15 Engine. It is for modelers who want higher performance than a .12 size engine in their 1/10 scale kits such as Nitro Hawk, Buggy and Street. This Version Comes With a Pull Starter.
ABC (Aluminum Brass Chrome) Construction
Oversized Machined Aluminum Blue/Silver Anodized Cylinder Head
Channelled Beam Connecting Rod for Improved Oil Flow
Precision Ball Bearings
Large-Bore, High-Flow Carburetor
Double O-Ring Seals on High and Low Needles
Industry-Standard Mounts and Crankshaft Lengths to Fit Most Applications.
This package includes:
One Assembled Engine With Pull Starter
One Air Cleaner (Black rubber with Black foam element)
One Full Instruction Book and Parts Exploded View
One "Traxxas" Decal Sheet
Installed Glow Plug (standard long--no idle bar)
A 1/10 scale kit to put it into and 5%-20% Glow Fuel
Appropriate exhaust system


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its frustrating in a really bad way(shards)
Quick Apps: Shards and Hedronism for the iPhone
John Welch wrote in to let us know about Shards and Hedonism. Shards also has a free
demo lite version, Shardsette available via the App Store.
Shards is a hybrid that combines inlay and breakout style games. Each level is composed of four types of triangles: floor, empty, wall, and void. You must first fill the empty triangles by tapping triangle based shapes in that appear in a bubble that the player controls with tilt movements. Hedronism is a permutation puzzle. You start on a faceted globe and can move to your immediately adjacent neighbors changing their color in a predictable sequence. The goal is to turn the globe into any single color in the shortest time possible. Advancing to the next level increases the number of colors. Best time is kept for individual levels and for the difficulties easy, medium and hard.
Thanks John!
Have something to say about this story? Leave a comment! Need help with something else? Ask in our forums!
Reader comments
Quick Apps: Shards and Hedronism for the iPhone
Care to elaborate?
Yes, please elaborate... As the developer we are always interested in finding out what people like or don't like about the game. And of course we have forums where you can voice your thoughts if you want.


text:
Report Finds Faith Organizations Building Community, Improving Health Through Healthy Foods
The report, Faith and Food: Action Strategies for Healthy Eating, found that churches, synagogues and other faith organizations throughout
"Faith communities are important supporters of healthy eating because of their strong presence in neighborhoods and their commitment to the well-being of community members," said
IATP joined forces with Blue Cross' Prevention Minnesota initiative, which works to improve the health of Minnesotans by combating the root causes of cancer and heart disease, of which unhealthy eating is a leading factor. Physical inactivity and unhealthy eating combined contribute to obesity, cancer, cardiovascular disease and diabetes. Together, they are the second leading cause of preventable death and disease in
"With two-thirds of Americans overweight or obese, we need many solutions to stop this alarming trend," said Dr.
Case studies in the report include:
- St. Alban's Episcopal Church in
Bolivar, Mo., manages three gardens and three orchards from which they harvest and provide both fresh and preserved fruits and vegetables for anyone who wants them.
- Guardian Angels Catholic Church in
Oakdale, Minn., manages a volunteer-based community garden that provides fruits and vegetables for local food shelves.
- Taqwa Eco-Food, a food cooperative in
Chicago, Ill., works to meet the needs of people wanting to purchase local meats raised and processed within the principles of Islam.
- Central
Baptist Churchand Bethlehem Baptist Church of Columbia, S.C., runs the "Dash of Faith" cooking program to help church cooks prepare healthier foods.
- Sixteen Interfaith Communities in
Eugene, Ore., connect urban residents with local farmers and community-supported agriculture (CSA) farms in which residents purchase shares and receive deliveries of harvested fruits and vegetables.
- St. Paul Jewish Community Center in
St. Paul, Minn., arranges for members to purchase shares in a local CSA farm that uses farming practices based on Jewish beliefs.
- Plymouth Congregational Church and Stevens Square Community Organization of
Minneapolis, Minn., operate a community garden, food shelf and farmers market at the church.
- Central Presbyterian Church in downtown
St. Paul, Minn., provides a weekly healthy community lunch program for members and the surrounding community.
- Upper Sand Mountain Parish of northeastern
Alabamaoperates a food pantry, community and church gardens, cannery and healthy eating education program.
- Body and Soul healthy eating program throughout the U.S. helps African-American congregations improve eating among their members.
- The Hindu Temple of
Minnesotain Maple Grove, Minn., organizes a weekend healthy lunch program for both members and non-members.
IATP is working to identify and expand opportunities for faith communities to support local foods, sustainable agriculture and healthy eating. They invite others to share the efforts of their own faith community to improve access to healthy food by visiting www.iatp.org/faith and adding their stories to complement the case studies highlighted in this report.
A PDF of the complete Faith and Food: Action Strategies for Healthy Eating report can be downloaded at www.iatp.org/faith or www.bluecrossmn.com/preventionminnesota.
The Institute for Agriculture and Trade Policy works locally and globally at the intersection of policy and practice to ensure fair and sustainable food, farm and trade systems. www.iatp.org.
Blue Cross and Blue Shield of
SOURCE Blue Cross and Blue Shield of


text:
They fixed the animation for Magic Missile, and it looks a lot better. Though in the case of the archer ranger they'll probably take cues from Legolas so yeah extreme archery.
Home | Search | Today's Post
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- Neverwinter Discussion
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- About wizard combat animations
Results 51 to 60 of 60
Thread: About wizard combat animations
03-04-2013, 04:19 AM #51Hero of the North
- Join Date
- Feb 2013
03-10-2013, 03:06 PM #52Knight of the Feywild
- Join Date
- Mar 2013
I love my wizard, but every time I look at those two fingers up in the air, I can't help but to envision a rabid gynecologist and wait for the sound of latex gloves snapping against flesh.
03-10-2013, 03:09 PM #53Banned
- Join Date
- Mar 2013
I'm going to call my wizard Quagmire!
03-11-2013, 02:37 AM #54PWE User
Hi all,
- Join Date
- Feb 2013
been watching this video on youtube
(which i saw it mentioned in another thread below)
Does anybody see a problem with the animation moves?
From my perspective it looks like animations from another class, monk for example ?
Moving while in combat reminds a bit of bruce lee legendary style?
In overall not very wizzy style?
What you think?
P.S: personally i think the wizard combat animation doesnt quite fit, bit strange since thief combat animation looks greatIt helps if you check for previous topics on this. I refer you to:
Wizard's attack stance is not good
done not even a month ago.
Anyway, if you think the male wizard is bad, have a look at the female!. it really looks like she took a dump and it looks like its the same mechanics as the male, making the female look like a she-male, and thou that could be an option for not discriminating cross-gender-player, then i still belive that it is a really bad animation taking away the femine feeling of playing a female wizard. Please please please have a look at the Cryptic. You can change this quite easy and it would make a world of dif for the spellcaster fanboys and girls.
I for one, am using alotta time creating my char and making it just right so i can put all the playing hours into the char and not get tired of it, but all that fades if it's gonna look like my char had an accident every time she goes into combat.
I can only hope that this is a beta mechanic, and it would be great if you could confirm if it is or is not.
EDIT: for some reason the vedeo doesn't jump into 23m29s as it should, but there you can see the horror.
Best Regards:
Last edited by archiloni; 03-11-2013 at 02:40 AM.
03-11-2013, 05:01 AM #55Guardian
- Join Date
- Jun 2012
A few specific requests:
- Please change the out-of-combat idle pose to one which is not embarassing to roleplay from. Imagine the character standing at the bar in the Moonstone Mask. Would we have a hand up in an arcane gesture? No, we would not.
- Please hook up a non-combat walk animation. I toggled on walk and moved forward with both hands raised. I'm fine with this animation in combat, but I would like a regular walk.
- Male and female animations for walking and running and idle stance. See, for example, the very fluid idle and walking and running animations for STO females. They're lovely.
- Ray of Enfeeblement: Any D&D player who regularly plays the wizard will tell you that Ray of Enfeeblement is GREEN. This is in every edition of the game. Please fix.
03-11-2013, 05:10 AM #56PWE User
- Join Date
- Mar 2013
03-11-2013, 05:48 AM #57Guardian
- Join Date
- Jun 2012
I'll check that out. Thanks for the tip!
03-12-2013, 08:31 PM #58PWE User
- Join Date
- Jan 2013
I'm digging the animations. Its like Mage Kata.
I should name my next Wizard, Kiara. Water Tribe!
03-13-2013, 06:59 AM #59Guardian
- Join Date
- Feb 2013
Honestly, I like the martial arts feel of the wizards combat-stances and movements. The fingers are not well loved. But I always marvel at how rigid the minds of people are.
So you imagined that Wizards moved differently. Long bears, broken backs, and probably some spectacles. Can't have young energetic wizards?
Please, I know it is hard from personal experience, but try to judge something on it's own merits, not how much it confirms your expectations.
03-14-2013, 06:04 AM #60PWE User
- Join Date
- Mar 2013
For the spell animations, sure. However, his combat idle and walking animations look like he has a broom shoved up his ***. That's not a "martial arts feel".
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29 year old woman | Sauk Rapids, MN, USA | Seeking men 25-35 in Saint Cloud, Minnesota, United States
Don't let the fear of striking out keep you from playing the game...Babe Ruth Well-behaved women seldom make history...
I am a very open, honest, straight forward, and goal driven individual. I'm open to trying new things or laying low and just hanging out. I enjoy spending time with my family and friends and having a good time. I really enjoy traveling so a a few trips a year is an absolute must! I have a fun and outgoing personality and the littlest of things make me smile. I'm pretty easily entertained and always up and ready for a good time!
Coffee and conversation , Dining out , Movies/Videos , Music and concerts , Exploring new areas , Nightclubs/Dancing , Playing sports , Religion/Spiritual , Travel/Sightseeing , Watching sports
Aerobics, Baseball, Basketball, Dancing, Football, Hockey, Inline skating, Running, VolleyBall, Walking / Hiking
I exercise 3-4 times per week.
I like Cats
Middle of the Road
Not too sure I have a favorite hot spot in town...but I love going to Destin Beach, FL every year...or the occassional trip to some place warm, sunny, and where the ocean and beaches goes on for miles...
Minnesota State University Moorhead, Moorhead, MN
My favorite TV show by far is friends. My favorite kind of music is anything except extreme hard rock and rap. I have Nickleback playing on Pandora and whatever that station pulls up seems to be a good fit for music for me. And food...I'm not picky!
I enjoy spending time with family and friends...going out, being outdoors, playing sports, working out, traveling, laying low, etc. I'm open and game for anything and I'm pretty easy to please so you best be ready for a good time!
I'm sure something nursing related because I am a nurse and in college...nothing to exciting
Z{{Cta}} {{#if HasMoreInfo}} ?{{CtaSecondary}} {{/if}}
|What she is looking for
|5'8" (172cms)
|5'9" (175cms) to 6'11" (210cms)
|Body type:
|Athletic and toned
|About average, Athletic and toned
|Blue, Brown, Grey, Green, Hazel
|Light brown
|Black, Light brown, Dark brown, Blonde, Dark blonde, Bald
|No Way
|No Way
|Social Drinker
|Social Drinker
|Medical / Dental / Veterinary / Fitness
|Administrative / Secretarial, Artistic / Creative / Performance, Executive / Management, Financial / Accounting / Real Estate, Labor / Construction, Legal, Medical / Dental / Veterinary / Fitness, Political / Govt / Civil Service / Military, Retail / Food services, Retired, Sales / Marketing, Self-Employed / Entrepreneur, Student, Education / Teacher / Professor, Technical / Science / Computers / Engineering, Travel / Hospitality / Transportation, Other profession, Nonprofit / Volunteer / Activist, Law enforcement / Security / Military, Fashion / Model / Beauty, Architecture / Interior design
Currently I am working as RN (Nurse Manager) and love what I do! Every day is a new and different day! No repeat days in this career field!
|I'll tell you later
|$35,001 to $50,000, $50,001 to $75,000, $75,001 to $100,000, $100,001 to $150,000, $150,001+
|Never Married
|Never Married, Widow / Widower
|Have kids:
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|White / Caucasian
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|Christian / Catholic
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My faith is important to me and I hope to find someone who feels the same way. I want to be able to have a faith filled relationship with that special someone.
|Bachelors degree
|High school
I'm currently finishing up my Bachelors of Science Degree in Nursing at MSU-Moorhead. From there, I am pursuing my Master or Doctorate degree...I hope to be a Nurse Practioner, Traveling Nurse, Nursing Anesthetist, or Legal Nursing Consultant.


text:
Is Psychological Well-Being Linked to the Consumption of Fruit and Vegetables?
- David G. Blanchflower,
- Andrew J. Oswald,
- Sarah Stewart-Brown
- … show all 3 hide
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
Little is known about the influence of people's diet on their psychological well-being. This study provides evidence of a link between the consumption of fruit and vegetables and high well-being. In cross-sectional data, happiness and mental health rise in an approximately dose–response way with the number of daily portions of fruit and vegetables. Well-being peaks at approximately 7 portions per day. We document this relationship in three data sets, covering approximately 80,000 randomly selected British individuals, and for seven measures of well-being (life satisfaction, WEMWBS mental well-being, GHQ mental disorders, self-reported health, happiness, nervousness, and feeling low). The pattern is robust to adjustment for a large number of other demographic, social and economic variables. Reverse causality and problems of confounding remain possible. We discuss the strengths and weaknesses of our analysis, how government policy-makers might wish to react to it, and what kinds of further research—especially randomized trials—would be valuable.
- Blanchflower, DG, Oswald, AJ (2004) Well-being over time in Britain and the USA. Journal of Public Economics 88: pp. 1359-1386 CrossRef
- Blanchflower, DG, Oswald, AJ (2008) Is well-being U-shaped over the life cycle?. Social Science and Medicine 66: pp. 1733-1749 CrossRef
- Blanchflower, DG, Oswald, AJ (2011) International happiness: A new view on the measure of performance. Academy of Management Perspectives 25: pp. 6-22 CrossRef
- Capacci, S, Mazzocchi, M (2011) Five a day, a price to pay: An evaluation of the UK program impact accounting for market forces. Journal of Health Economics 30: pp. 87-98 CrossRef
- Carter, KN, Krus, K, Blakely, T, Collings, S (2011) The association of food security with psychological distress in New Zealand and any gender differences. Social Science and Medicine 72: pp. 1463-1471 CrossRef
- Clark, AE, Frijters, P, Shields, MA (2008) Relative income, happiness, and utility: An explanation for the Easterlin Paradox and other puzzles. Journal of Economic Literature 46: pp. 95-144 CrossRef
- Dave, DM, Kelly, IR (2012) How does the business cycle affect eating habits?. Social Science and Medicine 74: pp. 254-262 CrossRef
- Diener, E (1994) Assessing subjective well-being: progress and opportunities. Social Indicators Research 31: pp. 103-157 CrossRef
- Diener, E, Suh, EM, Lucas, RE, Smith, HL (1999) Subjective well-being: Three decades of progress. Psychological Bulletin 125: pp. 276-302 CrossRef
- Dolan, P, Peasgood, T, White, M (2008) Do we really know what makes us happy? A review of the economic literature on the factors associated with subjective well-being. Journal of Economic Psychology 29: pp. 94-122 CrossRef
- Easterlin, RA (2003) Explaining happiness. Proceedings of the National Academy of Sciences of the USA 100: pp. 11176-11183 CrossRef
- Farnworth, CR (2009) Well-being is a process of becoming: Respondent-led research with organic farmers in Madagascar. Social Indicators Research 90: pp. 89-106 CrossRef
- Goldberg, DP, Gater, T, Sartorious, N, Ustun, TB, Piccinelli, M, Gureje, O, Rutter, C (1997) The validity of two versions of the GHQ in the WHO study of mental illness in general health care. Psychological Medicine 27: pp. 191-197 CrossRef
- Graham, C (2005) Insights on development from the economics of happiness. World Bank Research Observer 20: pp. 201-231 CrossRef
- Graham, C (2008) Happiness and health: Lessons—and questions—for public policy. Health Affairs 27: pp. 72-87 CrossRef
- Hu, YJ, Stewart-Brown, S, Twigg, L, Weich, S (2007) Can the 12-item General Health Questionnaire be used to measure positive mental health?. Psychological Medicine 37: pp. 1005-1013 CrossRef
- Jacka, FN, Pasco, JA, Myletun, A (2010) Association of western and traditional diets with depression and anxiety in women. American Journal of Psychiatry 167: pp. 305-311 CrossRef
- Layard, R (2005) Happiness: Lessons from a new science. Allen Lane, London
- Ness, AR, Powles, JW (1997) Fruit and vegetables, and cardiovascular disease: A review. International Journal of Epidemiology 26: pp. 1-13 CrossRef
- Piqueras, J. A., Kuhne, W., Vera-Villarroel, P., van Straten, A., & Cuijpers, P. (2011). Happiness and health behaviours in Chilean college students: A cross-sectional survey. BMC Public Health, 11, Article number: 443. doi:10.1186/1471-2458-11-443.
- Powdthavee, N (2009) What happens to people before and after disability? Focusing effects, lead effects, and adaptation in different areas of life. Social Science and Medicine 69: pp. 1834-1844 CrossRef
- Propper, C, Jones, K, Bolster, A, Burgess, S, Johnston, R, Sarker, R (2005) Local neighbourhood and mental health: Evidence from the UK. Social Science and Medicine 61: pp. 2065-2083 CrossRef
- Shelton, NJ (2009) Regional risk factors for health inequalities in Scotland and England and the "Scottish effect". Social Science and Medicine 69: pp. 761-767 CrossRef
- Shields, MA, Wheatley Price, S (2005) Exploring the economic and social determinants of psychological well-being and perceived social support in England. Journal of the Royal Statistical Society (Series A) 168: pp. 513-537 CrossRef
- Tennant, R, Hiller, L, Fishwick, R, Platt, S, Joseph, S, Weich, S, Parkinson, J, Secker, J, Stewart-Brown, SL (2007) The Warwick-Edinburgh mental well-being scale (WEMWBS): Development and UK validation. Health and Quality of Life Outcomes 5: pp. 1477-7527 CrossRef
- Tsai, AC, Chang, TL, Chi, SH (2012) Frequent consumption of vegetables predicts lower risk of depression in older Taiwanese—results of a prospective population-based study. Public Health Nutrition 15: pp. 1087-1092 CrossRef
- Title
- Is Psychological Well-Being Linked to the Consumption of Fruit and Vegetables?
- Journal
Social Indicators Research
Volume 114, Issue 3 , pp 785-801
- Cover Date
- 2013-12-01
- 10.1007/s11205-012-0173-y
- Print ISSN
- 0303-8300
- Online ISSN
- 1573-0921
- Publisher
- Springer Netherlands
- Additional Links
- Topics
- Keywords
- Subjective well-being
- Healthy food
- Diet
- Mental health
- Depression
- Happiness
- Industry Sectors
- Authors
- David G. Blanchflower (1)
- Andrew J. Oswald (2) (3)
- Sarah Stewart-Brown (4)
- Author Affiliations
- 1. Department of Economics, Dartmouth College, Hanover, NH, USA
- 2. IZA Institute, Bonn, Germany
- 3. Department of Economics and CAGE Centre, University of Warwick, Coventry, UK
- 4. Warwick Medical School, University of Warwick, Coventry, UK


text:
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Work Crew Services Laborer Workers, and Low Rate Trade-Hands. Contractor Network, Delaware County, Main Line and Philadelphia.


text:
3 Finger Pickin' Banjo Songbook
By Mike Bailey
3 Finger Pickin' Banjo Songbook composed by Mike Bailey. For Banjo (5-String). Squareback saddle-stitched, SongBook. Old Time. Beginning. Book/CD Set. 112 pages. Published by Mel Bay Publications, Inc (MB.93612BCD).
ISBN 9780786628872. Old Time. 8.5 x 11 inches.
All of the arrangements in this book were especially prepared for the beginning bluegrass banjo student. Written in G tuning, melody and accompaniment tabs are shown for 51 banjo favorites! Lyrics are included with the melody tabs. Includes a CD in split-track format with performance of all the songs in the book.


text:
Glenn Dorsey DL SF 5 months ago
Dorsey (arm) was placed on season-ending injured reserve Saturday, Matt Maiocco of CSNBayArea.com reports.
Dorsey spent most of the year on short-term on IR after undergoing biceps surgery in August, and he did not end up playing after being activated late last month. Cornerbak Marcus Cromartie and guard Andrew Tiller were added to the active roster, with NaVorro Bowman (knee) moved to IR along with Dorsey.
Glenn Dorsey DL SF 6 months ago
Dorsey (biceps) is inactive for Sunday's game against Washington.
After being activated from short-term injured reserve earlier in the week, Dorsey was expected to play Sunday, but instead he'll spend another week in street clothes. The 49ers are a bit thin along the defensive line after the recent loss of Ian Williams to a leg injury.
Glenn Dorsey DL SF 6 months ago1 Comment
The 49ers have activated Dorsey (biceps) from IR/designated to return, the Sacramento Bee reports.
The timing of Dorsey's activation coincides with that of fellow nose tackle Ian Williams landing on IR, so Dorsey figures to have a key role in the 49ers' defense out of the gate.
Glenn Dorsey DL SF 9 months ago
Dorsey (biceps) is expected to be placed on the 49ers' injured reserve/designated to return list on Tuesday, CSN Bay Area reports.
Dorsey was slated to start at nose tackle before tearing his biceps Aug. 1 and is now expected to miss three-and-a-half months following surgery. With the possibility of returning some time after the mid-season mark, Dorsey will be named San Francisco's designated player to return, ruling him out of practice until after Week 6 and out of games until after Week 8. While Dorsey rehabs, Quinton Dial is expected to open the regular season as the 49ers' starter at nose tackle.
Glenn Dorsey DL SF 9 months ago
Dorsey (biceps) is expected to miss three and a half months after undergoing successful surgery on August 4, Matt Maiocco of CSN Bay Area reports.
The three and a half month timetable is on the short end of the expected recovery from an injury like the one Dorsey sustained, so this is good news for the nose tackle and for the 49ers. Coach Jim Harbaugh is hoping that Dorsey will be ready by late-November to early-December to help out the team down the stretch. He is the leading candidate to be placed in the injured reserve - with a designation to return list. Dorsey recently signed a two-year extension with the 49ers.
Glenn Dorsey DL SF 9 months ago
Dorsey (biceps) agreed to a two-year contract extension with the 49ers on Tuesday, Matt Maiocco of CSNBayArea.com reports.
Dorsey is uncertain to play in 2014 after tearing his biceps in training camp, but in signing Dorsey to a new deal, they'll be able to ensure he doesn't hit the open market next summer. He'll likely be placed on injured reserve to start the season, but there's a good chance he could be the club's designated player to return if he progresses well in his recovery.
Glenn Dorsey DL SF 10 months ago
Dorsey (biceps), who will undergo surgery Monday, is at best hoped to be able to return late in the regular season, CSN Bay Area reports.
Glenn Dorsey DL SF 2 years ago
The 49ers gave DL Glenn Dorsey no assurances on his role when they signed him to a two-year, $6 million deal on March 13.
"No, I'm coming into it trying to play whatever they want me to play," he said. "I don't have no set spot." Dorsey is penciled in (lightly) at nose tackle, but at 6-foot-1 and just over 300 pounds, it's not an ideal position in the Niners' 3-4. The 49ers would prefer Dorsey to fill Ricky Jean-Francois' shoes as a utility lineman capable of backing up all three positions up front.
Glenn Dorsey DL SF 2 years ago
The 49ers plan to play newly signed Glenn Dorsey at nose tackle in their 3-4.
At 6-foot-1 and just over 300 pounds, Dorsey will be an undersized nose tackle in the Jay Ratliff mold. The 49ers will likely give him plenty of penetrating opportunities as opposed to using Dorsey as a two-gap plugger. Dorsey's two-year deal is worth $6 million. He received a $2.285 million signing bonus.
Glenn Dorsey DL SF 2 years ago
49ers agreed to terms with DE Glenn Dorsey, formerly of the Chiefs.
Dorsey made San Francisco his lone free-agent visit. The Chiefs initially wanted him back, but they went out and signed DL Mike DeVito on Tuesday. Dorsey is a quality run defender, and he'll slide into the role vacated by free agent DL Ricky Jean-Francois, acting as the top backup at the end spots.


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Love Music? Sylvia Theater's the Place to Be Tuesday Night for Benefit Concert
By Shannon Greene / firstname.lastname@example.com
YORK – Educator Ron Wright shifts focus from school matters to making music Tuesday, when he debuts as bassist for Ansel Couch and Tracy Johnson.
They'll cover Simon and Garfunkel, The Eagles and Seals and Crofts – "the music of our youth," said Wright, an assistant superintendent for Clover schools.
And it's all for a good cause.
The trio will perform with Woody's Music musicians at the Sylvia Theater in downtown York during a benefit for Hospice and Community Care, a Rock Hill-based organization that provides emotional support and medical care for patients at the end of their life. The show is open to the community with a $10 suggested donation. All profits go to Hospice's Danny Guyton Music Enrichment Endowment, which promotes the physical, social and/or emotional well-being of Hospice patients and families through music.
Wright, a former band director who spent 13 years in one of the area's premier beach bands, is excited about the show.
"I was blown away by Ansel and Tracy," Wright said. "I can't believe they're undiscovered. Those guys' harmonization is natural – it's an amazing sound."
Wright said anyone who appreciates acoustic music of the 1960s and 1970s will love the show, regardless of their age.
In fact, Wright had so much fun at their first practice that he hopes something more comes out of it.
"I've missed the music scene," Wright said, quipping that he wouldn't mind "this turning into a permanent gig."
But Wright's especially eager about supporting the cause.
"Cancer's really hit me pretty close over the last five years," he said. "My mom's a survivor of breast cancer."
Tony Caruso, community relations coordinator with Hospice, said the musicians and event organizers have all been "touched by watching the tender care that Hospice has given their family."
He said the goal for Tuesday's concert is to raise more awareness for Hospice and help people understand that death, much like music, touches everyone.
Caruso said the audience is in for a treat.
"I absolutely love Ansel Couch," Caruso said. "He's one of my favorites. He's just so smooth. The guy's an ace – they don't get much better than that. … And he's doing it all for the love of Hospice."
Want to go?
What: Benefit for Hospice and Community Care
Where: Sylvia Theater, 27 N. Congress St., York
When: 8 p.m. Tuesday; doors open at 7 p.m.
Cost: $10 suggested donation
Details: Call (803) 329-1500
(c) 2008 Herald; Rock Hill, S.C.. Provided by ProQuest LLC. All rights Reserved.


text:
Founded in 1998, Tribridge is a leading IT services provider dedicated to helping customers leverage cloud and on-premise business solutions to become more productive, profitable, competitive and secure. With more than 450 employees throughout the U.S., Tribridge provides award-winning Microsoft Dynamics, SharePoint, application development, infrastructure and security, and other solutions to its 3,500 customers nationwide.
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AvePoint is a global technology company and proven software leader. Since its founding in 2001, AvePoint has become the world's largest provider of enterprise-class governance, compliance, and management solutions for social enterprise collaboration platforms. AvePoint helps more than 10,000 customers – including many Fortune 500 companies and government agencies – meet their specific business objectives by enabling collaboration with confidence. AvePoint, Inc. is headquartered and maintains its principal operational center in Jersey City, NJ, with wholly owned operational centers in the USA, Canada, Australia, South Africa, United Kingdom, France, Germany, Netherlands, Switzerland, Japan, Singapore, and China. AvePoint is a Depth Managed Microsoft Gold Certified Application Development Partner and Gold Certified Collab
|Source: PRWeb
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