text:
A subspecialty certification by the Board of Internal Medicine. Practitioners focus on diseases of the lungs and airways. Pulmonologists diagnose and treat pneumonia, cancer, asthma, occupational diseases, sleep disorders, emphysema, and other complex disorders of the lungs. They evaluate lung function, examine the bronchial airways, and prescribe and monitor mechanical ventilation. Many pulmonary disease experts are also experts in critical care.
1-10 of 61
225 N Jackson Ave
San Jose, CA 95116
300 Pasteur Dr Ste A175
Stanford, CA 94305
5401 Norris Canyon Rd Ste 308
San Ramon, CA 94583
19830 Lake Chabot Rd Ste D
Castro Valley, CA 94546
701 E El Camino Real
Mountain View, CA 94040
2101 Forest Ave Ste 112
San Jose, CA 95128
815 Hyde St Ste 300
San Francisco, CA 94109
2112 McKee Rd Ste B
San Jose, CA 95116
3300 Webster St Ste 608
Oakland, CA 94609
795 El Camino Real
Palo Alto, CA 94301

subset: commoncrawl


text:
Office of the Attorney General - State of Texas John Cornyn |
September 27, 1999 Mr. Merril E. Nunn
OR99-2704 Dear Mr. Nunn: You ask us to reconsider Open Records Letter No. 99-1347 (1999). Your request for reconsideration was assigned ID# 127690. The City of Amarillo (the "city") received a request for copies of documents in a particular internal investigation file. In Open Records Letter No. 99-1347 (1999), we concluded that the city must withhold incident report number 98-80057 from disclosure under section 552.101 of the Government Code in conjunction with section 58.007 of the Family Code. We further concluded that the remaining documents in the investigation file are not excepted from disclosure under section 552.103 of the Government Code and must be released to the requestor. In Open Records letter No. 99-1813 (1999), you asked us to reconsider whether section 552.103 applied to the requested documents. You also asked for additional guidance about which documents are confidential under section 58.007 of the Family Code. You did not, however, resubmit the documents at issue to this office for review. Furthermore, you did not respond to our facsimile request to resubmit copies of the documents to this office. Based on your failure to provide information requested under section 552.303(c) of the Government Code, this office affirmed Open Records Letter No. 99-1813. See Gov't Code § 552.303(e) (stating that failure to comply with requirements of section 552.303(c) results in legal presumption that requested information is public). You now ask that we reconsider Open Records letter No. 99-1813 (1999) based on your claim that your office did not receive our facsimile. Ironically, you have still not provided the documents at issue to this office for review. Accordingly, this office will no longer entertain any additional arguments or discussion on this matter. The city must release the information at issue without further delay. Open Records letter No. 99-1813 (1999) is hereby affirmed. If you have questions about this ruling, please contact our office. Sincerely, June B. Harden
JBH/ch Ref: ID# 127690 cc: Mr. Mark H. Taboada


text:
Hanna's Blend/Sig Shop(:
Example: Rules: 1. Be Patient. I do have life outside of TDP. 2. Please give me credit (: 4. Don't be rude. Form: Picture (Celeb/Cartoon/etc)- Text- Text Color- Anything else?- CLOSED |
First requester!!!
Picture (Celeb/Cartoon/etc)-Kate Nash Text- I Use Mouthwash <3 Text Color- Blue and Purple Anything else?- Nope, thank you! :] |
Thanks for requesting! Here's your blend and if you want me to change anything, just say :D Hope you like it-- |
*squeal* I love it!! Thank you thank you thank you!!!
Your welcome!
I'm glad you like it :D x |
Picture (Celeb/Cartoon/etc)- Johnny Depp
Text- JD <3 Text Color- neon green Anything else?- nopperz, thank you |
Xx_isolated_heart_xX Here's your blend, hope you like it! |
=D love it!!! thnx!
Picture (Celeb/Cartoon/etc)- Ke$ha
Text- Pedicure On My Toes <3 Text Color- Purple and Yellow Anything else?- Nope :] Thank you! |
Here's your blend;
All times are GMT -4. The time now is 11:21 PM. |
© 2007 The Doll Palace


text:
Congratulations to the Brewers of Milwaukee, obtainers of the NL Wild Card. After playing baseball like a bunch of actual employees from the Miller Factory to begin the month of September, the Brewers rebounded just well enough down the stretch to earn their first playoff berth since 1982. The year of my birth.
Before we get to the Mets, let's not discount what a remarkable few weeks it's been for The Crew. With the exception of a couple weeks when they were within striking distance of the Cubs, they've pretty much been playing for the Wild Card all season. They started Sepetember 3-11 before their manager got fired with 12 regular season games left. Their interim hire, Dale Sveum was met with snickers and more than a little derision, yet here they are. 7-5 under Sveum and in the playoffs. That sealed the deal because... oh fine let's talk about the Mets.
After the Mets fired Willie Randolph, they received that coveted new manager "bounce" that the Brewers did, but it appears they just did it too early. No amount of Manuel/Delgado magic could make up for the universally maligned bullpen, the injuries to John Maine and the professional death of Pedro Martinez. This team went 4-6 in their last ten. Not good, to be sure. But hardly the epic collapse that the bloodthirsty masses will be labeling it this morning.
It was just horrible timing for a minor downturn.
Update: I had totally forgotten about this, until reading Big League Stew this morning. I expect some horrifying pictures to be making their way out of Milwaukee anytime now.


text:
If a JSP is having include directive with aother JSP. Then how the translated Servlet looks. Will is genrate 2 servlets? If so how the main servlet include the other servlet?
Post your Comment
JSP include directive tag JSP include directive tag What is include directive tag in JSP
JSP include directive tag JSP include directive tag What is include directive tag in JSP? Hi, The JSP include directive includes a static file or sends a request to a dynamic file. or The JSP include directive is used to include
Include directive vs Include Action Include directive vs Include Action Include directive: Include directive (<%@ include %>) includes file into the JSP page at compile time. Include directive should be used
The Include Directive in JSP Page The Include Directive in JSP Page  ... directive of the JSP. You will learn about what is include and how to implement...: <html> <head><title>Include Directive JSP Page.<
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JSP page directive tag JSP page directive tag What is page directive tag in JSP?. Hi, The answer given below: The page directive applies to an entire JSP file and any of its static include files, which together are called a translation
Type of JSP Directive Tag Type of JSP Directive Tag How many types of directive tag in the JSP? Hi, The answer is given below: There are three types of directive tag. 1. page 2. Include 3. Tag Lib Thanks
jsp:include action tag the directive tag. The jsp include tag is used to include the file or any other...jsp:include action tag In this section we will discuss about JSP "include" action tag. The jsp "include" tag is used to include
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text:
Spyder Winner Athletic Fit Insulated Ski Pant (Women's)
Quick Specs
- Waterproofing: 7/10
- Fit: Relaxed
- Warmth: 8/10
Available Colors
Blue Light
Product Details
Please Note: This style is from a previous season
The Spyder Winner Athletic Fit Insulated Ski Pant is a relaxed-fitting women's pant with all the necessary performance. This pant is reliably waterproof and warmly insulated so you can ride in wet conditions without discomfort. Spyder used low-profile insulation that won't make you feel bulky or interfere with the flattering fit. The Spyder Winner Ski Pant has a clean and simplistic design with just a coin pocket at the waist and 2 back pockets for holding essentials.
- Fabric Rating: 10K Waterproof / 10K Breathable
- Shell Material: Stretch polyester with Xt.L laminate
- Lining Material: Nylon taffeta lining
- Insulation: 60g Thinsulate insulation
- Athletic fit is more relaxed
- Spylon™ DWR repels water and liquid stains
- Critical seam tape prevents moisture from seeping through exposed seams
- Boot gaiters fit around boots to keep out snow
- Articulated for natural fit and easy movement
- Velcro coin pocket at waist
- Velcro back pockets hold essentials
Questions and Answers
User Reviews
I'm a 40-something mom and wanted ski pants that felt like they were riding beneath my belly button but still look current. These pants have a really comfortable fit and the material is really nice. I've known about Spyder gear for decades but didn't know about the lifetime product guarantee until I received these. That was a nice surprise. Good buy for the money (I looked at other pants of lesser quality at a higher price).
This fitted ski pant looks great. I ordered a size eight and they fits perfectly. The quality of these Spyder ski pants is very good, and the pink is really cute. Looking forward to wearing these many times.
This is my second pair. Best fit and toasty warm. I've tried on dozens of different brands and styles. These are my faves.
Color was a little more toward orange than pink. Fit is great. Used them for ski trip to Copper Mountain, CO. They were warm and waterproof so did perform very well.
I bought these (along with a Spyder Prevail ski jacket) for my girlfriend for our upcoming snowboarding trip to Colorado because she didn't have snow gear. These are excellent snow pants, and fit well. They are toasty warm and very water repellant. They do exactly what they were designed to do, and look great! She loves the Spyder logo too!


text:
Please note that changing your country whilst shopping will remove all items from your basket.
You are here:
Presenting Bumble and bumble Blow Dry Balm
Presenting Bumble and bumble Invisible Oil
Presenting Bumble and bumble Cityswept Finish
Bumble and bumble Bestsellers
Bumble and bumble Salon Locator
Copyright © The Boots Company PLC. All rights reserved. Boots.com is a trading name of Boots UK Limited. Registered office: Nottingham NG2 3AA.Registered in England: company number 928555. Registered VAT number 116300129. Registered pharmacy number 1092488.


text:
Highlight: Karel Appel
Spotlight: Phillips London
Featured: Douglas Udell Gallery
Now On: Stories of the Future
Top Lot: Bert Stern
View Catalogue: Edward Sheriff Curtis
Over 9 MillionAuction Results
Featured Member:Galerie Peter Zimmermann
Upcoming Auction atPerrin, Royere, Lajeuness
Sample Report
A very fine impression.
Skating was a traditional subject for Flemish paintings and prints going back to Breugel, Avercamp and Essais van de Velde; and also among artists in Holland during Ensor's time including Kruseman, Koekkoek, and Schelfhout. But perhaps the traditional theme of carefree partying skaters is not precisely what Ensor had in mind; the ominous figures in the left foreground, including one with a decidedly wolf-like profile, and the scattering of fallen figures, strikes an off note. And virtually all the figures who have not fallen, extending far into space, seems to be on the verge of doing so.
Whatever the meaning of all this, the patterning of the skaters against the darkening winter sky and the bare trees creates one of Ensor's most memorable scenes.


text:
Preview Image |
Item images are no longer available |
Currently | $102.00 USD | |
Item ID # | 12317306 | |
Quantity | 1 | |
Start Time | 1/21/2013 6:00:00 AM PT | |
End Time | 1/31/2013 9:45:00 PM PT | |
Seller | Great Falls Goodwill | |
Location | Great Falls, MT | |
Payment | MUST BE RECEIVED WITHIN seven (7) DAYS from auction close. Available Payment Methods: |
Shipping / Handling | Buyer pays shipping No International Shipments This item ships via Shipping Weight 6 lbs. Get Estimated Shipping & Handling Minimum shipment weight is 1lb., items weighing less than 1lb. will be calculated at the 1lb. rate. Items are shipped using a major carrier usually within 5 business days after receipt of payment. Shipping charges are calculated at payment time. A 5% handling fee applies to all purchased items, regardless of delivery method including pick up. |
Returns Policy | Please read our return policy below. | |
High bidder | j****c For the protection of our buyers, the bidder name is only visible to the bidder. | |
# of bids |
13 (
bid history)
Frequently asked bidding questions:
can't remember my Buyer ID and Password.
is proxy bidding?
is a reserve price?
I lose by less than the minimum bid increment?
Round Stain Glass Bird Hanging Current Price: $10.99 Seller: Great Falls Goodwill | 1984 Ceramic Smiling Pig - Universal Statuary Current Price: $7.99 Seller: Great Falls Goodwill | "That�s Why I Come Up Here" Art By Glenn Fox Current Price: $99.99 Seller: Goodwill Industries of Southern California |
Item images are no longer available
This is a matted 24.5" x 18 double image art deco piece signed by Robert Reinhardt Von Liski. These images appear to be original works due to the following reasons: we do not see printers dots, the signature is in pencil and appears indented and shiny from the lead, pencil lines are visable along the edges of the leaves, flowers and head pieces. We cannot authenticate this work, we are not experts. There is a 2" crease half way up one of the images. Light water damage across the majority of both images. Please email with any questions and visit the link to find more information on this artist. http://www.google.com/search?sourceid=navclient&aq=&oq=robert&ie=UTF-8&rlz=1T4GGHP_enUS428US430&q=robert+reinhardt+von+liski&gs_l=hp..4.0l4j188.8.131.52.4088210...........0.unXOghwgILE&pbx=1
View other items for sale by this seller
Thank You for Shopping With
Great Falls Shopgoodwill.com
Seller Contact Information:
Great Falls Goodwill1201 7th Street South Great Falls, MT, 59405 406-453-0311 |
Return Policy:
Returns will not be accepted without prior authorization. Items may be returned within seven (7) days of receipt if the merchandise was damaged during shipping or if there was a major distortion in the description. In case of shipping damage, save all packing material and contact Great Falls, MT Goodwill ASAP. The buyer will be responsible for all charges associated with a return. PLEASE NOTE THAT WE DO NOT REFUND SHIPPING AND HANDLING CHARGES.


text:
User talk:TeeVeeed
- 1 Your recent edits
- 2 Teahouse
- 3 Re:Logo reducing
- 4 Please fill out our brief Teahouse guest survey
- 5 August 2012
- 6 Orphaned non-free image File:The Real Housewives of New Jersey.jpg
- 7 Disambiguation link notification for May 28
- 8 Your submission at Articles for creation
- 9 Talkback
- 10 July 2013
- 11 DRN Restructure
- 12 all edits missing on July 25
- 13 A kitten for you!
- 14 Diner (film)
- 15 Message
- 16 Message
- 17 Tildes
- 18 Alternate accounts
- 19 The new face of DRN: TeeVeeed
- 20 Your involvement with DRN
- 21 Wikipedia talk:Articles for creation/Jessie Wiseman concern
- 22 Your draft article, Wikipedia talk:Articles for creation/Jessie Wiseman
- 23 DRN needs assistance
Your recent edits[edit]
Hello. In case you didn't know, when you add content to talk pages and Wikipedia pages that have open discussion, you should sign your posts by typing four tildes ( ~~~~ ) at the end of your comment. You could also click on the signature button or located above the edit window. This will automatically insert a signature with your username or IP address and the time you posted the comment. This information is useful because other editors will be able to tell who said what, and when they said it. Thank you. --SineBot (talk) 02:11, 30 April 2012 (UTC)
Please note that all old questions are archived. Message added by Lunashy (Lunashy (talk) 02:36, 30 April 2012 (UTC)). You can remove this notice at any time by removing the {{teahouse talkback}} template.
Re:Logo reducing[edit]
You don't need to do anything. A bot will come along and resize the logo and remove the reduce tag when it's done. We hope (talk) 02:38, 30 April 2012 (UTC)
OH! Thank-you. Also, I would prefer to use the other license (promotional) if possible because that was more in-line with the permission that was granted when I downloaded the graphic. Is there a way to change that or should I wait 'till the bot comes-along? HousewifeHater 02:47, 30 April 2012 (UTC)
- Let me go back and take care of that also. BTW--the only time to worry that something's going to disappear is when a notice says something about the image being deleted or being deleted in X number of days unless you take care of (fill in the blank). ;-)We hope (talk) 02:52, 30 April 2012 (UTC)
- A done deal! :-) We hope (talk) 02:55, 30 April 2012 (UTC)
Muuy Thank-You! Yeah that is exactly what I was worried about because I thought that I saw something that said that the clock was ticking-something about "48 hours"...maybe that has something to do with the bot that re-sizes?? Also-I want to make sure that I use the graphic/and license correctly because I would like to start cleaning-up some of the other Real Housewives pages HousewifeHater 02:57, 30 April 2012 (UTC)
- These Wikipedia:Template messages/Deletion are the ones that say something serious is up. The bot usually does the resizing within those 48 hours. ;-) We hope (talk) 03:02, 30 April 2012 (UTC)
TY♥ HousewifeHater 03:08, 30 April 2012 (UTC)
You can remove this notice at any time by removing the {{Talkback}} or {{Tb}} template.
Please fill out our brief Teahouse guest survey[edit]
Hello fellow Wikipedian, the hardworking hosts and staff at WP:Teahouse would like your feedback! We have created a brief survey meant to help us better understand the experience of new editors on Wikipedia. You are being selected to participate in our survey because you edited the Teahouse Questions or Guests pages sometime in the last few months.
Click here to be taken to the survey site.
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Happy editing,
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This message was sent via Global message delivery on 00:31, 22 May 2012 (UTC)
August 2012[edit]
{{unblock|reason=Your reason here ~~~~}}
, but you should read the guide to appealing blocks first. -- Boing! said Zebedee (talk) 21:43, 3 August 2012 (UTC)TeeVeeed (block log • active blocks • global blocks • autoblocks • contribs • deleted contribs • abuse filter log • creation log • change block settings • unblock)
Request reason:
Decline reason:
If you want to make any further unblock requests, please read the guide to appealing blocks first and then use the {{unblock}} template again. If you make too many unconvincing or disruptive unblock requests, you may be prevented from editing this page until your block has expired.
- See User talk:184.108.40.206 for details of original block. -- Boing! said Zebedee (talk) 22:31, 3 August 2012 (UTC)
Orphaned non-free image File:The Real Housewives of New Jersey.jpg[edit]
Thanks for uploading File:The Real Housewives of New Jersey.jpg. The image description page currently specifies that the image is non-free and may only be used on Wikipedia under a claim of fair use. However, the image is currently not used in any articles on Wikipedia. If the image was previously in an article, please go to the article and see why it was removed. You may add it back if you think that that will be useful. However, please note that images for which a replacement could be created are not acceptable for use on Wikipedia (see our policy for non-free media).
Note that any non-free images not used in any articles will be deleted after seven days, as described in the criteria for speedy deletion. Thank you. Senator2029 ‖ Talk 19:15, 27 April 2013 (UTC)
Disambiguation link notification for May 28[edit]
Hi. Thank you for your recent edits. Wikipedia appreciates your help. We noticed though that when you edited Atlantic City, New Jersey, you added a link pointing to the disambiguation page Imitation of Life (check to confirm | fix with Dab solver). Such links are almost always unintended, since a disambiguation page is merely a list of "Did you mean..." article titles. Read the FAQ • Join us at the DPL WikiProject.
It's OK to remove this message. Also, to stop receiving these messages, follow these opt-out instructions. Thanks, DPL bot (talk) 14:53, 28 May 2013 (UTC)
Your submission at Articles for creation[edit]
- If you would like to continue working on the submission, you can find it at Wikipedia talk:Articles for creation/Jessie Wiseman.
- To edit the submission, click on the "Edit" tab at the top of the window.
- If you need any assistance, you can ask for help at the Articles for creation help desk, or on the . Please remember to link to the submission!
- You can also get live chat help from experienced editors.
- Thank you for your contributions to Wikipedia! 78.26 (I'm no IP, talk to me!) 01:18, 15 July 2013 (UTC)
Message added 03:24, 15 July 2013 (UTC). You can remove this notice at any time by removing the {{Talkback}} or {{Tb}} template.
78.26 (I'm no IP, talk to me!) 03:24, 15 July 2013 (UTC)
July 2013[edit]
Your recent editing history at The Great Gatsby (2013 film) shows that you are currently engaged in an edit war. Being involved in an edit war can result in your being blocked from editing—especially if you violate the three-revert rule, which states that an editor must not perform more than three reverts on a single page within a 24-hour period. Undoing another editor's work—whether in whole or in part, whether involving the same or different material each time—counts as a revert. Also keep in mind that while violating the three-revert rule often leads to a block, you can still be blocked for edit warring—even if you don't violate the three-revert rule—should your behavior indicate that you intend to continue reverting repeatedly.
To avoid being blocked, instead of reverting please consider using the article's talk page to work toward making a version that represents consensus among editors. See BRD for how this is done. You can post a request for help at a relevant noticeboard or seek dispute resolution. In some cases, you may wish to request temporary page protection. — Statυs (talk, contribs) 04:18, 15 July 2013 (UTC)
I think that I will take it to IRC thank-youTeeVeeed (talk) 04:19, 15 July 2013 (UTC)
- Good idea. I definitely agree with you that it's an Australian film. I'm not even sure how it's even an American film; it's only tie is that the distributor is American. But I'm not sure how much that really matters. It's clear the other editor is having no interest in discussing the matter. — Statυs (talk, contribs) 04:23, 15 July 2013 (UTC)
TY-I didn't even start it, trying to follow procedure but instead getting pulled into warring. Plus I resent the additional clarifications and cites that I added being "poofed"-like that.TeeVeeed (talk) 04:28, 15 July 2013 (UTC)
- The other editor finally responded on the talk page that the film was distributed by Warner Bro. But there is also a link to "Baz"-"Boz"? (a producer?) in a secondary source titled, "Baz/Boz says GG is "Australian". If there is some policy involved with countries and movies, that would be different, but the financial assistance provided, (and probably the controversy surrounding that)-should probably be included.TeeVeeed (talk) 04
- 42, 15 July 2013 (UTC)
DRN Restructure[edit]
There seems to be a problem with the DRN page this morning.[1]]
I was not able to get to our page to post my comment because the links to open disputes are all broken. I am going to be unavailable for most of the day so I'm leaving my comment here which you can post if you wish, or, I will try again at the end of the day when I'm back home.
Thank you for your help.
- If comments could stay focused on the text only I think we could make useful progress. It's very hard to look at text and comment when simultaneously your character is being attacked. I still think we need a neutral third party arbitrator in cases where consensus can't be reached.
LoreMariano (talk) 12:47, 18 July 2013 (UTC)
- I'm trying to fix something with how the dispute is listed.
I'm sorry if you feel attacked with anything that has been said there so far, but I assure you that any comments that I made about trying to solve the problem by following the usual policy of Wikipedia was not aimed at you or any other editors personally. I think that someone such as myself who looked at the article for the first time, not knowing anything at all about the topic, is a pretty good representative of a user of Wikipedia.TeeVeeed (talk) 11:56, 19 July 2013 (UTC)
all edits missing on July 25[edit]
So all of my edits except today's are not showing-weirdHousewifehader (talk) 18:35, 25 July 2013 (UTC)
A kitten for you![edit]
Housewifehader (talk) 08:02, 26 July 2013 (UTC)
Diner (film)[edit]
I'm just wondering about the source of this edit. Thanks. Oh, and I think it's too long and somebody will remove it. Anna Frodesiak (talk) 06:01, 28 July 2013 (UTC)
Hello. You have a new message at Anna Frodesiak's talk page. Anna Frodesiak (talk) 08:08, 28 July 2013 (UTC)
Hello. You have a new message at Anna Frodesiak's talk page. Anna Frodesiak (talk) 00:08, 29 July 2013 (UTC)
Hi, I notice that you are leaving edit summaries with four tildes in them ~~~~, probably due to the message SineBot left on your account when you first started. I wanted to let you know that leaving these in edit summaries is ineffectual and just clutters the field. Tildes are required when discussing on talk pages, it is how you sign your posts by leaving them at the end of a line, as wikicode inside the box. The Wiki substs them automatically into a signature. This process does not happen in edit summaries, which are intended to be concise digests of what you did. Individual edits are always "signed" with your name in the database, so we can always tell who did them and there is no need to sign. I hope that clears it up for you. Elizium23 (talk) 04:23, 29 July 2013 (UTC)
- WHAT? I had no idea! Ty for letting me know about that. It might take awhile to get out of that habit.So-don't sign when editing articles? Wow.Housewifehader (talk) 05:11, 30 July 2013 (UTC)
Alternate accounts[edit]
I note that you are editing under both User:Housewifehader and User:TeeVeeed. The policy on that is at WP:SOCK#LEGIT and I do not see that you are using alternate accounts for an illegitimate purpose. But, with a previous block for block evasion, I would very strongly recommend that you disclose your alternate accounts on your TeeVeeed user page (not here on your talk page) using one of the user boxes listed here and be very, very careful not to use them for any purpose which might even remotely be thought by someone to be illegitimate. Best regards, TransporterMan (TALK) 20:01, 29 July 2013 (UTC)
- Thank-you for the advice. I will attempt to try that but I am having a lot of trouble staying with one account! All of my contributions keep vanishing, (so it looks like i have been here less-than four days!), and the system keeps logging me out. I am really thinking about trying a CLEANSTART, just to get a new account at this point, no SP intended, and i have never SP'd or tried to intentionally pretend that i am not one person here. That SP investigation that was alleged actually was between myself and another(S?) editor, because I agreed with his edits so I was accused of being one of his/their socks. It wasn't even about me being a sock really.OH-and my agreement to not be banned from the SP bs, was that I would log-in with a user name, and really I had better luck staying with the same identity when I was IP-editing. Now I have to look for my IP, my old name, and my new name, and 90% of the contributions that I make while logged-in are not showing-up when I want to check on my older edits with those screen-names. That's why I'm thinking that it might be worth a try to start another account and drop this one?Housewifehader (talk) 05:07, 30 July 2013 (UTC)Housewifehader (talk) 05:03, 30 July 2013 (UTC)
The new face of DRN: TeeVeeed[edit]
Recently the Dispute Resolution Noticeboard underwent some changes in how it operates. Part of the change involved a new list of volunteers with a bit of information about the people behind the names.
You are listed as a volunteer at DRN currently, to update your profile is simple, just click here. Thanks, Cabe6403(Talk•Sign) 17:15, 7 August 2013 (UTC)
Your involvement with DRN[edit]
Hi there, I noticed that you haven't been as active at DRN as you was before. DRN has been a bit backlogged lately and we could use some extra hands. We have updated our volunteer list to a new format, Wikipedia:Dispute resolution noticeboard/Volunteers (your name is still there under the old format if you haven't updated it) and are looking into ways to make DRN more effective and more rewarding for volunteers (your input is appreciated!). If you don't have much time to volunteer at the moment, that's fine too, just move your name to the inactive list (you're free to add yourself back to active at any time). Hope to see you again soon :) Steven Zhang (talk) 13:19, 25 September 2013 (UTC)
OOps sorry I just received this message. Thank-you for letting me know about inactive status. I'll see if there is still a backlog.188.8.131.52 (talk) 00:40, 19 November 2013 (UTC)-oops again, that was me not logged-nHousewifehader (talk) 00:42, 19 November 2013 (UTC)
Wikipedia talk:Articles for creation/Jessie Wiseman concern[edit]
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Your draft article, Wikipedia talk:Articles for creation/Jessie Wiseman[edit]
Hello TeeVeeed. It has been over six months since you last edited your WP:AFC draft article submission, entitled "Jessie Wiseman".
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DRN needs assistance[edit]
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Best regards, TransporterMan 15:52, 8 January 2015 (UTC) (current DRN coordinator)


text:
Expert Review
Dan Romascanu (primary), Bert Wijnen (secondary)
This MIB module defines a Textual Convention that provides an indication of the general hardware type of a particular physical entity. Copyright (C) The IETF Trust (2013). The initial version of this MIB module was published in RFC-ietf-eman-rfc4133bis-06; for full legal notices see the RFC itself. Supplementary information may be available at: http://www.ietf.org/copyrights/ianamib.html


text:
Pittsburgh veterans get free ride to National World War II Memorial
UPDATED 1:11 PM EDT May 21, 2013Leonard Puma boards a bus in Monroeville to go to Washington and touch the names of his fallen friends for the first time. The trip evokes memories that are embedded in the minds of these brave men who often keep their war stories to themselves.
The views expressed are not those of this site, this station or its affiliated companies. By posting your comments you agree to accept our terms of use.blog comments powered by Disqus


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Did any of the show goers on here get a chance to see or even listen to these little standmounters ?
They look like they might be real giant killers.
Did any of the show goers on here get a chance to see or even listen to these little standmounters ?
They look like they might be real giant killers.
"Eat food, drink liquids, shite in a bog."
I have just bought Loosends pair of Q Acoustics 1010 which have just arrived here, and I can honestly say I am completely amazed at how good they are.
I know they have a good reputaion at the budget end , and from what i've read on here Gromits ( i think ) system with q acoustics in had excellent reviews at scalford.
The concept 20s have a rrp of £350 plus £200 for the matching stands . Be interesting to read a proper review on them . Hopefully on here!
"Eat food, drink liquids, shite in a bog."
I'm being sent a pair on Friday. I'm rather looking forward to them.
The saddest day of your life isn't when you decide to sell out. The saddest day of your life is when you decide to sell out and nobody wants to buy.
Look forward to hearing your thoughts on them Ed.
From the pictures i've seen of them on the matching stands if they sound half as good as they look they should be crackers.
"Eat food, drink liquids, shite in a bog."
Excellent - will be interested to read of what you think of them.
I love the little 2010i's - they do need a fair bit of running in (they sound slighty dim-witted, flabby and slow when fresh out of the box) and IME respond well to plenty of current from an amp with well-damped bass. I've had mine on the end of 4 different amps now, and each time the amp has got bigger, the little Q's have improved.
They look very interesting indeed, look forward to reading and hearing them!
I would also be interested to hear opinions on these.
Now that my Obelisks are gone, I am temporarily running my Q 2010i (taken from my home cinema setup) with my Krell FPB300 and the results are shockingly good! (It helps that the 2010i are on Target R2 stands).
I must post a pic: £9k power amp with £120 speakers
Hehe, I can see a Wigwam group power buy on Q Acoustics speakers!
I'm currently using some little Mordaunt Short MS10i (Pearl I think), I think they are terrific.
Last edited by freefallrob; 20-03-2013 at 04:22 PM.
damn tempted to get some 2020i and a denon dm39 dab thingy and just be done with it!
As I'm so happy with the 2010i's, I've been toying with the idea of getting a pair of 2020i's to try but after a long listening sesh yesterday afternoon (with just me in the house so could crank things up hurrah!) the little ones just integrate so well in the room I'm loath to risk upsetting the balance.
Think it might be time to go cartridge/phonostage shopping instead.
That's exactly the situation I'm in at present - trying to resist the temptation to 'improve' the system with 2020i
Another dilemma is that the Krell will be departing soon (going back to its original owner) so am trying to figure out what will replace it and if the 'magic' will go with it. I've just hooked up my standby amp (a Marantz PM6010KI) and the sound has deflated somewhat Still tonally very nice, but the snap, least edge definition and involvement has reduced.
Despite their low price tag, these title 2010i are real divas! They don't get out of bed for cheap amplification!
Question is do I retain the Krell just to drive a pair of £120 Richer Sounds specials?
I've found they need a little bit of owner participation too to get the best out of them - getting their positioning right took quite some time, but they're so revealing they soon let you know when things are right. Amp-wise, my dad uses a pair of 2010i's (the first pair I bought for him, to swap for his ProAcs) with a clamshell Brio and whilst they sound ok, they really don't sing anywhere near the same as they do on the end of my big Sony amp. The Q's are just too much for the Rega.
Peter Empson at Deco Audio (who sells the whole Q range) had been raving about them for some time and as usual he's come up trumps in recommending these.
I was also oggling these the other day. I like the dedicated stands. Nicely conceived and designed.
I\'m gonna eat your brains and gain your knowledge.
Do you think it's an outright power thing, or is there more to it than that? I ask because I am looking at replacements for the Krell and am wondering whether something like a Sugden A21a or Puresound A10 would be man enough for the task.
Tell me about it. The man has a great pair of ears. Listening to his recommendations has always resulted in a successful and fantastic sounding system.Peter Empson at Deco Audio (who sells the whole Q range) had been raving about them for some time and as usual he's come up trumps in recommending these.
I preferred the CA S30's to these..


text:
US 20080025943 A1 Abstract Compositions, methods of manufacture and methods of treatment for post-myocardial infarction are herein disclosed. In some embodiments, the composition includes at least two components. In one embodiment, a first component can include a first functionalized polymer and a substance having at least one cell adhesion site combined in a first buffer at a pH of approximately 6.5. A second component can include a second buffer in a pH of between about 7.5 and 9.0. A second functionalized polymer can be included in the first or second component. In some embodiments, the composition can include at least one cell type and/or at least one growth factor. In some embodiments, the composition(s) of the present invention can be delivered by a dual bore injection device to a treatment area, such as a post-myocardial infarct region.
Claims(43) 1. A composition comprising:
a first mixture comprising a first functionalized polymer in a first buffer at approximately physiological osmolality; a second buffer at approximately physiological osmolality; a second functionalized polymer, wherein the second functionalized polymer is combined with one of the first mixture or the second buffer; and a substance having at least one cell-adhesion site combined with the first mixture, wherein the first mixture and the second buffer comprise a gel at pH 7.2 when combined. 2. The composition of
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simultaneously injecting from a dual bore delivery device (a) a first mixture comprising a first functionalized polymer and a substance having at least one cell-adhesion site in a first buffer at physiological osmolality and (b) a second buffer at physiological osmolality to a post-myocardial infarct region. 30. The method of
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Description Post-myocardial infarction treatments and compositions. Ischemic heart disease typically results from an imbalance between the myocardial blood flow and the metabolic demand of the myocardium. Progressive atherosclerosis with increasing occlusion of coronary arteries leads to a reduction in coronary blood flow, which creates ischemic heart tissue. �Atherosclerosis� is a type of arteriosclerosis in which cells including smooth muscle cells and macrophages, fatty substances, cholesterol, cellular waste product, calcium and fibrin build up in the inner lining of a body vessel. �Arteriosclerosis� refers to the thickening and hardening of arteries. Blood flow can be further decreased by additional events such as changes in circulation that lead to hypoperfusion, vasospasm or thrombosis. Myocardial infarction (MI) is one form of heart disease that results from the sudden lack of supply of oxygen and other nutrients. The lack of blood supply is a result of a closure of the coronary artery (or any other artery feeding the heart) which nourishes a particular part of the heart muscle. The cause of this event is generally attributed to arteriosclerosis in coronary vessels. Formerly, it was believed that an MI was caused from a slow progression of closure from, for example, 95% then to 100%. However, an MI can also be a result of minor blockages where, for example, there is a rupture of the cholesterol plaque resulting in blood clotting within the artery. Thus, the flow of blood is blocked and downstream cellular damage occurs. This damage can cause irregular rhythms that can be fatal, even though the remaining muscle is strong enough to pump a sufficient amount of blood. As a result of this insult to the heart tissue, scar tissue tends to naturally form. Various procedures, including mechanical and therapeutic agent application procedures, are known for reopening blocked arties. An example of a mechanical procedure includes balloon angioplasty with stenting, while an example of a therapeutic agent application includes administering a thrombolytic agent, such as urokinase. Such procedures do not, however, treat actual tissue damage to the heart. Other systemic drugs, such as ACE-inhibitors and Beta-blockers, may be effective in reducing cardiac load post-MI, although a significant portion of the population that experiences a major MI ultimately develop heart failure. An important component in the progression to heart failure is remodeling of the heart due to mismatched mechanical forces between the infarcted region and the healthy tissue resulting in uneven stress and strain distribution in the left ventricle. Once an MI occurs, remodeling of the heart begins. The principle components of the remodeling event include myocyte death, edema and inflammation, followed by fibroblast infiltration and collagen deposition, and finally scar formation from extra-cellular matrix (ECM) deposition. The principle component of the scar is collagen which is non-contractile and causes strain on the heart with each beat. Non-contractility causes poor pump performance as seen by low ejection fraction (EF) and akinetic or diskinetic local wall motion. Low EF leads to high residual blood volume in the ventricle, causes additional wall stress and leads to eventual infarct expansion via scar stretching and thinning and border-zone cell apoptosis. In addition, the remote-zone thickens as a result of higher stress which impairs systolic pumping while the infarct region experiences significant thinning because mature myocytes of an adult are not regenerated. Myocyte loss is a major etiologic factor of wall thinning and chamber dilation that may ultimately lead to progression of cardiac myopathy. In other areas, remote regions experience hypertrophy (thickening) resulting in an overall enlargement of the left ventricle. This is the end result of the remodeling cascade. These changes also correlate with physiological changes that result in increase in blood pressure and worsening systolic and diastolic performance. Compositions, methods of manufacture and methods of treatment for post-myocardial infarction are herein disclosed. In some embodiments, the composition includes at least two components. In one embodiment, a first component can include a first functionalized polymer and a substance having at least one cell adhesion site combined in a first buffer at a pH of approximately 6.5. A second component can include a second buffer in a pH of between about 7.5 and 9.0. A second functionalized polymer can be included in the first or second component. In some embodiments, the composition can include at least one cell type and/or at least one growth factor. In some embodiments, the composition(s) of the present invention can be delivered by a dual bore injection device to a treatment area, such as a post-myocardial infarct region. Bioscaffoldings formed of two components and applied in situ to the left heart ventricle can be used to treat post-myocardial infarction tissue damage. �Bioscaffolding� and �two-component gelation system� and �gelation system� are hereinafter used interchangeably. Examples of two-component gelation systems include, but are not limited to, alginate construct systems, fibrin glues and fibrin glue-like systems, self-assembled peptides, synthetic polymer systems and combinations thereof. Each component of the two-component gelation system may be co-injected to an infarct region by a dual-lumen delivery device. Examples of dual-lumen delivery devices include, but are not limited to, dual-needle left-ventricle injection devices, dual-needle transvascular wall injection devices and the like. In some applications, the two-component gelation system includes fibrin glue. Fibrin glue consists of two main components, fibrinogen and thrombin. Fibrinogen is a plasma glycoprotein of about 340 kiloDaltons (kDa) in its endogenous state. Fibrinogen is a symmetrical dimer comprised of six paired polypeptide chains, alpha, beta and gamma chains. On the alpha and beta chains, there is a small peptide sequence called a fibrinopeptide which prevents fibrinogen from spontaneously forming polymers with itself. In some embodiments, fibrinogen is modified with proteins. Thrombin is a coagulation protein. When combined in equal volumes, thrombin converts the fibrinogen to fibrin by enzymatic action at a rate determined by the concentration of thrombin. The result is a biocompatible gel which gelates when combined at the infarct region. Fibrin glue can undergo gelation between about 5 to about 60 seconds. Examples of fibrin glue-like systems include, but are not limited to, Tisseel� (Baxter), Beriplast P� (Aventis Behring), Biocol� (LFB, France), Crosseal� (Omrix Biopharmaceuticals, Ltd.), Hemaseel HMN� (Haemacure Corp.), Bolheal (Kaketsuken Pharma, Japan) and CoStasis� (Angiotech Pharmaceuticals). In some applications, the two-component gelation system includes self-assembled peptides. Self-assembled peptides generally include repeat sequences of alternating hydrophobic and hydrophilic amino acid chains. The hydrophilic amino acids are generally charge-bearing and can be anionic, cationic or both. Examples of cationic amino acids are lysine and arginine. Examples of anionic amino acids are aspartic acid and glutamic acid. Examples of hydrophobic amino acids are alanine, valine, leucine, isoleucine or phenylalanine. Self-assembled peptides can range from 8 to 40 amino acids in length and can assemble into nanoscale fibers under conditions of physiological pH and osmolarity. In sufficient concentration and over time, the fibers can assemble into an interconnected structure that appears macroscopically as a gel. Self-assembled peptides typically undergo gelation between several minutes to several hours. Examples of self-assembled peptides include, but are not limited to: AcN-RARADADARARADADA-CNH2 (RAD 16-II) wherein R is arginine, A is alanine, D is aspartic acid, and Ac indicates acetylation; VKVKVKVKV-PP-TKVKVKVKV-NH2 (MAX-1) wherein V is valine, K is lysine and P is proline; and AcN-AEAEAKAKAEAEAKAK-CNH2 wherein A is alanine, K is lysine and E is glutamic acid (EAK16-II). In some applications, the two-component gelation system is an alginate construct system. One component may be an alginate conjugate (or alginate alone) which can include alginate and a protein constituent. The second component may be a salt. Examples of alginate conjugates can include, but are not limited to, alginate-collagen, alginate-laminin, alginate-elastin, alginate-collagen-laminin and alginate-hyaluronic acid in which the collagen, laminin, elastin, collagen-laminin or hyaluronic acid is covalently bonded (or not bonded) to alginate. Examples of salts which can be used to gel the alginate constructs include, but are not limited to, calcium chloride (CaCl2), barium chloride (BaCl2) or strontium chloride (SrCl2). In one embodiment, the alginate construct is alginate-gelatin. The molecular weight of the gelatin may be in the approximate range of 5 kDa to 100 kDa. The relatively low molecular weight of gelatin offers processing advantages in that it is more soluble and has lower viscosity than hydrogels of higher molecular weight. Another advantage of gelatin is that it contains from 1 to 4 RGD (arginine-glycine-aspartic acid peptide sequence) sites per molecule. RGD is a common cell adhesion ligand and would increase the retention of cells within the infarct zone where the bioscaffolding is formed. The cells retained by the RGD sites may be cells co-injected with the bioscaffolding components or dispersed throughout a component of the system. The gelatin may be a porcine gelatin or a recombinant human gelatin. The porcine gelatin is a hydrolyzed type 1 collagen extracted from porcine skin. In one embodiment, the molecular weight of the porcine gelatin is approximately 20 kDa. The human gelatin is produced by bacteria using human genetic material. The human recombinant gelatin is equivalent to the porcine gelatin but may reduce the likelihood of an immune response when injected into an infarct region of a human subject. Alginate is a linear polysaccharide derived from seaweed and contains mannuronic (M) and guluronic acid (G), presented in both alternating blocks and alternating individual residues. It is possible to use some of the carboxyl groups of the alginate as sites to graft useful cell adhesion ligands, such as collagen, laminin, elastin and other peptide fragments of the ECM matrix, forming an alginate conjugate, because alginate does not have RGD groups for cell attachment. The alginate-gelatin conjugate can be formed of approximately 1% to 30% and more particularly approximately 10% to 20% gelatin (either porcine or human recombinant) and approximately 80% to 90% alginate. A relatively lower proportion of gelatin is used in the conjugate to retain gelation capacity of native alginate because the carboxyl groups of alginate that cause the gelation may be bound up in the alginate-gelatin conjugate. In some embodiments, the two-component gelation system includes polyethylene glycols. PEG is a synthetic polymer having the repeating structure (OCH2CH2)n. A first component may be a polyethylene glycol (PEG) polymer functionalized with at least two nucleophilic groups. Examples of nucleophilic groups include, but are not limited to, thiol (�SH), thiol anion (�S−), and amine (�NH2). A �nucleophile� is a reagent which is attracted to centers of positive charge. A nucleophile participates in a chemical reaction by donating electrons to an electrophile in order to form a chemical bond. A second component may be a PEG polymer functionalized with at least two electrophilic groups. Examples of electrophilic groups include, but are not limited to, N-hydroxy succinimide ester (�NHS), acrylate, vinyl sulfone, and maleimide. �NHS, or succinimidyl, is a five-member ring structure represented by the chemical formula �N(COCH2)2. An �electrophile� is a reagent attracted to electrons that participates in a chemical reaction by accepting an electron pair in order to bond to a nucleophile. The total number of electrophilic and nucleophilic groups should be greater than 4. In some embodiments, two functionalized PEGs comprising a PEG functionalized with at least two nucleophilic groups and a PEG functionalized with at least two electrophilic groups can be combined in a 1:1 ratio. The PEGs can be stored in a 0.01M acidic solution at a pH below about 4.0. At room temperature and standard concentration, reaction and cross-linking between the two functionalized PEGs occurs beginning at approximately pH greater than 6.5. Under these conditions, reaction kinetics are slow. When 0.3 M basic buffer solution at pH about 9.0 is added to the PEGs, gelation occurs in less than 1 minute. This system exhibits poor cytocompatibility due to the low pH of the functionalized PEG solution and the high osmolality pH 9.0 buffer. �Cytocompatibility� refers to the ability of media to provide an environment conducive to cell growth. Additionally, this system does not include any cell adhesion sites. In some embodiments, a bioscaffolding is formed from combining functionalized polymers (bioscaffolding precursors) with an extra-cellular matrix (ECM) protein at physiological osmolality. The resulting bioscaffolding can be in a pH range of between about 6.5 and about 7.5. Examples of ECM proteins include, but are not limited to, collagen, laminin, elastin and fragments thereof, in addition to, proteins, protein fragments and peptides with cell adhesion ligands such as RGD groups. In some embodiments, cells can be added to the bioscaffolding precursors. Examples of cell types include, but are not limited to, localized cardiac progenitor cells, mesenchymal stem cells (osteoblasts, chondrocytes and fibroblasts), bone marrow derived mononuclear cells, adipose tissue derived stem cells, embryonic stem cells, umbilical-cord-blood-derived stem cells, smooth muscle cells or skeletal myoblasts. In some embodiments, growth factors can be added to the system. Examples of growth factors include, but are not limited to, isoforms of vasoendothelial growth factor (VEGF), fibroblast growth factor (FGF, e.g. beta-FGF), Del 1, hypoxia inducing factor (HIF I-alpha), monocyte chemoattractant protein (MCP-1), nicotine, platelet derived growth factor (PDGF), insulin-like growth factor 1 (IGF-1), transforming growth factor (TGF alpha), hepatocyte growth factor (HGF), estrogens, follistatin, proliferin, prostaglandin E1 and E2, tumor necrosis factor (TNF-alpha), interleukin 8 (II-8), hematopoietic growth factors, erythropoietin, granulocyte-colony stimulating factors (G-CSF) and platelet-derived endothelial growth factor (PD-ECGF). The polymers can include synthetic polymers, such as polyamino acids, polysaccharides, polyalkylene oxide or polyethylene glycol (PEG). The molecular weight of the compounds can vary depending on the desired application. In most instances, the molecular weight (mol. wt.) is about 100 to about 100,000 mol. wt., and more preferably about 1,000 to about 20,000 mol. wt. In some embodiments, the polymer is polyethylene glycol. As used herein, the term �polyethylene glycol(s)� includes modified and/or derivatized polyethylene glycols. According to some embodiments, a first functionalized PEG can be functionalized by at least two reactive groups, such as electrophilic groups. Examples of reactive groups include, but are not limited to, a succinimidyl group (�NHS), a vinyl group, such as acrylate, vinylsulfone, vinyl ether, allyl ether, vinyl ester, vinyl ketone or maleimide, and nitrophenolate or similar leaving group. According to some embodiments, a second functionalized PEG can be functionalized by at least two reactive groups, such as nucleophilic groups. Examples of reactive groups include, but are not limited to, a thiol group, an amino group, a hydroxyl group, phospine radical (PH2) and �CO�NH�NH2. Representative functionalized PEGs with electrophilic groups are shown in The branched conformation of the PEGs represented in In some embodiments, a bioscaffolding can include a first component with at least one functionalized PEG and an ECM protein, and a second component of buffer. �Component� hereinafter refers to one part of a two-part system and can include multiple constituents (e.g., a mixture). In one embodiment, the first component can include a mixture of a first functionalized PEG, such as �NHS PEG (or other functionalized PEG with at least two reactive groups), a second functionalized PEG, such as �SH PEG (or other functionalized PEG with at least two reactive groups), and an ECM protein. In some embodiments, the first component can include first functionalized polymer only, such as �NHS PEG (or other functionalized PEG with at least two reactive groups) and an ECM protein. In some embodiments, the first functionalized PEG can be combined with the second functionalized PEG in a 1:1 ratio. In some embodiments, e.g., the functionalized PEGs can be combined in a ratio less than 1:1. For example, the two PEGs can have different number of functional groups and, as a result, the PEG stoichiometry could be altered. Alternatively, the crosslinking density may be altered by varying the polymer ratio. In some embodiments, the functionalized PEGs are combined in the solid phase. When preparing to deliver to a treatment site, the mixture can be suspended in a pH 6.5 buffer at approximately physiological osmolality, i.e., 280-300 mOsm/kg H2O. Examples of buffers include, but are not limited to dilute hydrogen chloride and citrate buffers. The second component can include a buffer in a pH range from approximately 7.5 to 9.5 at a concentration from about 140 mM to about 150 mM. Examples of buffers include sodium phosphate and sodium carbonate buffers. The buffer can be at approximately physiological osmolality, i.e., 280-300 mOsm/kg H2O. In some embodiments, the second component can include an �SH PEG and the buffer (or other functionalized PEG with at least two reactive groups). In some embodiments, a cell type can be added to the first component. Examples of cell types include, but are not limited to, localized cardiac progenitor cells, mesenchymal stem cells (osteoblasts, chondrocytes and fibroblasts), bone marrow derived mononuclear cells, adipose tissue derived stem cells, embryonic stem cells, umbilical-cord-blood-derived stem cells, smooth muscle cells or skeletal myoblasts. For example, human mesenchymal stem cells (hMSC) can be added to the first component. In some embodiments, a growth factor can be added to the first component. In some applications, the functionalized PEGs can react with the growth factors which could stabilize the growth factors, extend their half-life or provide a mode for controlled release of the growth factors. The growth factors can act to help survival of injected hMSC or endogenous progenitor cells at the infarct region. In addition, the growth factors can aid direct endogenous progenitor cells to the injury site. In general, cells do not attach to PEG surfaces or gels formed from PEG polymers. That is, PEG polymers do not provide a cytocompatible environment for cells. Collagen or gelatin or any other ECM protein such as fibronectin, may be added to improve cytocompatibility. However, in the case of collagen, for example, the collagen added to the mixture of PEGs can make the mixture very viscous and therefore not conducive with catheter delivery systems. It is anticipated that the pH of the first component and the concentration of the second component, as described in embodiments of the invention, will increase the cytocompatibility of the cell types even with an ECM protein present. In some embodiments, the first component can be combined with the second component to produce a bioscaffolding at an infarct region. When combined, the resulting bioscaffolding gel can be at a pH of between 6.8 and 7.4. Although the low buffer concentration of the second component may slow the reaction down, the resulting gel can enable improved cytocompatibility. The ECM protein can provide cell adhesion cites to enable cell spreading and migration. �Cell spreading� refers to the naturally occurring morphology that some cells attain when they are allowed to grow on cytocompatible surfaces. In the case of hMSC, the natural morphology is a flattened, spindle-shaped morphology. In some embodiments, the N-terminus and lysine and arginine side groups of the ECM may react with the �NHS PEG. This may provide better mechanical stability of the gel and reduce the tendency of the gel to swell. This reaction is what forms the gel. In some embodiments, the �NHS group of the �NHS PEG can be replaced with a vinyl constituent such as acrylate, vinylsulfone, vinyl ketone, allyl ester, allyl ketone or maleimide group(s). When mixed with an �SH PEG at appropriate conditions, these groups can react with the thiol group(s) of the �SH PEG through a Michael type reaction. Michael type reactions are well known by those skilled in the art. In some embodiments, the reaction could be activated with a buffer in a pH range of between about 6.0 and about 9.0, by a catalytic amount of various amines or a combination thereof. It is anticipated that a Michael type reaction would contribute to the long term stability of the resulting gel since thioether bonds are formed as compared to the more hydrolytically labile thioester bonds formed from the reaction of thiols with activated esters. In some embodiments, the �NHS group of the �NHS PEG can be replaced with a leaving group such as a nitrophenolate. In some embodiments, the �SH group of the �SH PEG can be replaced with an amino group to form an amide bond when combined with an �NHS or alternatively functionalized PEG. Devices which can be used to deliver each component of the gel include, but are not limited to, dual-needle left-ventricle injection devices, dual-needle transvascular wall injection and dual syringes. Methods of access to use the minimally invasive (i.e., percutaneous or endoscopic) injection devices include access via the femoral artery or the sub-xiphoid. �Xiphoid� or �xiphoid process� is a pointed cartilage attached to the lower end of the breastbone or sternum, the smallest and lowest division of the sternum. Both methods are known by those skilled in the art. In some applications, first barrel 410 can include a first component of a two-component polyethylene glycol gelation system and second barrel 420 can include a second component of the system according to any of the embodiments described previously. A therapeutic amount of the resulting gel is between about 25 μL to about 200 μL, preferably about 50 μL. Dual syringe 400 can be used during, for example, an open chest surgical procedure. In one embodiment, delivery assembly 500 includes first needle 520 movably disposed within delivery lumen 530. Delivery lumen 530 is, for example, a polymer tubing of a suitable material (e.g., polyamides, polyolefins, polyurethanes, etc.). First needle 520 is, for example, a stainless steel hypotube that extends a length of the delivery assembly. First needle 520 includes a lumen with an inside diameter of, for example, 0.08 inches (0.20 centimeters). In one example for a retractable needle catheter, first needle 520 has a needle length on the order of about 40 inches (about 1.6 meters) from distal portion 505 to proximal portion 515. Lumen 510 also includes auxiliary lumen 540 extending, in this example, co-linearly along the length of the catheter (from a distal portion 505 to proximal portion 515). Auxiliary lumen 540 is, for example, a polymer tubing of a suitable material (e.g., polyamides, polyolefins, polyurethanes, etc.). At distal portion 505, auxiliary lumen 540 is terminated at a delivery end of second needle 550 and co-linearly aligned with a delivery end of needle 520. Auxiliary lumen 540 may be terminated to a delivery end of second needle 550 with a radiation-curable adhesive, such as an ultraviolet curable adhesive. Second needle 550 is, for example, a stainless steel hypotube that is joined co-linearly to the end of main needle 520 by, for example, solder (illustrated as joint 555). Second needle 550 has a length on the order of about 0.08 inches (0.20 centimeters). Referring to The proximal end of main needle 520 includes adaptor 570 for accommodating a substance delivery device (e.g., a component of a two-component bioerodable gel material). Adaptor 570 is, for example, a molded female luer housing. Similarly, a proximal end of auxiliary side arm 560 includes adaptor 580 to accommodate a substance delivery device (e.g., a female luer housing). The design configuration described above with respect to In one embodiment, catheter assembly 600 is defined by elongated catheter body 650 having proximal portion 620 and distal portion 610. Guidewire cannula 670 is formed within catheter body (from proximal portion 610 to distal portion 620) for allowing catheter assembly 600 to be fed and maneuvered over guidewire 680. Balloon 630 is incorporated at distal portion 610 of catheter assembly 600 and is in fluid communication with inflation cannula 660 of catheter assembly 600. Balloon 630 can be formed from balloon wall or membrane 635 which is selectively inflatable to dilate from a collapsed configuration to a desired and controlled expanded configuration. Balloon 630 can be selectively dilated (inflated) by supplying a fluid into inflation cannula 660 at a predetermined rate of pressure through inflation port 665 (located at proximal end 620). Balloon wall 635 is selectively deflatable, after inflation, to return to the collapsed configuration or a deflated profile. Balloon 630 may be dilated (inflated) by the introduction of a liquid into inflation cannula 660. Liquids containing treatment and/or diagnostic agents may also be used to inflate balloon 630. In one embodiment, balloon 630 may be made of a material that is permeable to such treatment and/or diagnostic liquids. To inflate balloon 630, the fluid can be supplied into inflation cannula 660 at a predetermined pressure, for example, between about one and 20 atmospheres. The specific pressure depends on various factors, such as the thickness of balloon wall 635, the material from which balloon wall 635 is made, the type of substance employed and the flow-rate that is desired. Catheter assembly 600 also includes at least two substance delivery assemblies 605 a and 605 b (not shown; see From the foregoing detailed description, it will be evident that there are a number of changes, adaptations and modifications of the present invention which come within the province of those skilled in the part. The scope of the invention includes any combination of the elements from the different species and embodiments disclosed herein, as well as subassemblies, assemblies and methods thereof. However, it is intended that all such variations not departing from the spirit of the invention be considered as within the scope thereof. Referenced by
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Another Problem with the "Right to be Forgotten"
History is riddled with examples where attempts to achieve one outcome actually led to the opposite result. In May, the European Court of Justice (ECJ) ruled that Europeans have the "right to be forgotten," the ability to request search engines to remove links from queries associated with their names if those results are irrelevant, inappropriate, or outdated. Just as Prohibition famously increased alcohol consumption, it would seem the "right to be forgotten," while intended to increase online privacy, may actually have the opposite effect, both by cataloging shameful information and incentivizing individuals to publicize the very materials people want forgotten.
Since the decision, Google has scrambled to meet Europe's demands by creating an online form to process removal requests and hiring new personnel to handle compliance. When individuals want information removed about themselves, they must submit verification of their identity, provide the URLs to be removed, and justify why they should be taken down. Google then verifies that the submitted information is accurate and meets the criteria for removal. Then, if the company decides to take the link down, it notifies the website where the content was posted of
The Nanny Police Are at IT Again
The Washington Post printed a story about how the Campaign for a Commercial-Free Childhood has submitted the opinions of six experts on child development to the Federal Trade Commission in support of CCFC's complaint against toy maker Fisher-Price for marketing its "Laugh and Learn" app for infants and small children.
One of the six experts, Herbert Ginsburg writes, "Existing research suggests that infants and very young children are not cognitively ready to learn key abstract ideas about numbers. Although some children at the upper bounds of this age range might learn to parrot some number words they are highly unlikely to learn important concepts of numbers."
To be sure I am not a child development expert (although I did study child development in college.) I am a parent of a wonderful daughter. When she was 19 months old I ran across a Fisher Price online game, "The ABC Game", which taught infants and toddlers their letters. (This was pre-tablet so I used a laptop). My daughter would press keys on my laptop and up would pop a picture of the letter, a picture of an animal whose first
If the Courts Do Not Recognize Technology Neutrality in the Wiretap Act, Congress Should Intervene
Yesterday the United States Court of Appeals for the Ninth Circuit ruled that a lawsuit against Google for illegal wiretapping could proceed.
The case involves Google's Street View project which provides online access to panoramic views of public streets in cities around the world. To build the database of images, Google sent vehicles into cities to photograph public streets. At times, these vehicles also unintentionally recorded data that users were transmitting over unencrypted wireless networks. The central claim of the lawsuit is that this collection of unencrypted data from wireless networks is a violation of the Wiretap Act. Google argued that the case should be dismissed because the Wiretap Act exempts "electronic communications" that are "readily accessible to the general public." In its ruling, the Court denied Google's motion to dismiss.
The basic logic of the Wiretap Act is that if people do not take action to make their communications private, then they do not have an expectation of privacy. For example, if two individuals use unscrambled CB radios to have a conversation, then other radio users are not in violation of the Wiretap Act if they hear this conversation.
RFID: Readily Forced Information Distortion
The sign of a civilization in decline is when there is widespread fear of the future and longing for the past. While America may not yet be in decline we are certainly fearing the future. Case in point, California's decision to back off its deployment of drivers' licenses with embedded radio-frequency identification chips (RFID) in them. RFID chips are small electronic devices embedded with a unique code that communicates with an electronic reader usually within a range of 1 to 2 inches.
We can thank the privacy-fundamentalists for this, for they love nothing better than to spread fear based on misinformation about technology. As supposedly pro-tech Wired Magazine writes, this is "spy-friendly technology." The article claims that "Privacy advocates worry that, if more states begin embracing RFID, the licenses could become mandatory nationwide and evolve into a government-run surveillance tool to track the public's movements." It goes on to say "law enforcement already monitors drivers' whereabouts via the mass deployment of license-plate readers. But the ability to scan for identification cards in public areas could evolve into another surveillance tool."
That sure scares me. I don't want the
Do Consumers Care About Online Privacy Anymore?
According to the latest online search trends, concerns about Internet privacy are so 2004.
If this sounds incredible to you, let me explain.
First, some background. An individual's search queries can reveal interesting information about their interests. When this data is amassed across many individuals, it can provide insights into consumers as a whole. Google is one of the first companies to make use of its large historical database of search engine queries to try to better understand consumers. Perhaps the most famous example of this is Google Flu Trends which uses both historical and real-time data to predict the level of influenza in the population across time.
Google has also made a version of its database of search queries available to the public in a product called Google Trends. Google Trends shows how many searches have been performed on a particular search term relative to the total number of searches. Individuals can use Google Trends to discover the relative popularity of search terms for a particular period of time or for a particular location. Google Trends does not show total search volume, but rather normalizes the data to
Privacy Zealots Say "Cookies for Me, None for Thee"
This op-ed originally appeared in ComputerWorld.
Last week, Brendan Eich, the chief technology officer and senior vice president of engineering at Mozilla, announced that the organization is planning to block third-party cookies in future versions of the Firefox Web browser. In addition, the Center for Internet and Society (CIS) at Stanford Law School announced that it has created a new organization called the "Cookie Clearinghouse," which will begin publishing blacklists for websites based on whether it believes a website's particular usage of cookies "makes logical sense." Mozilla will use these blacklists to decide which cookies to accept or deny.
Large-scale blocking of third-party cookies may have profound negative consequences on the future of the Internet. There are three main concerns. First, this practice will result in a loss of revenue from online advertising for many websites, and thus lead to less free content available to consumers. Second, it will cut off many legitimate business models for companies that collect and aggregate user data across the Internet to understand user behavior to design better websites, content and features. Third, it will limit the functionality of websites, both
California Law Would Criminalize "Revenge Porn." Guess Which Privacy Groups Oppose It?
The California Senate's Public Safety Committee passed SB 255 earlier this week to prohibit the distribution of "revenge porn"—the non-consensual distribution of intimate images of individuals. Groups like Without My Consent have been campaigning to get state laws changed to make this a crime. As the bill's chief sponsor State Senator Anthony Cannella says, "People who post or text pictures that are meant to be private as a way to seek revenge are reprehensible. Right now, there is no tool for law enforcement to protect the victims."
The legislation is fairly straightforward so I will quote it directly:
"This bill would make it a misdemeanor for any person who, with the intent to cause substantial emotional distress or humiliation to another person, by means of an electronic communication device, and without consent of the other person, electronically distributes, publishes, emails, hyperlinks, or makes available for downloading nude images of the other person along with personal identifying information of the other person."
This bill is a common sense solution to an incredibly offensive activity. Indeed, California's Public Safety Commission approved the legislation unanimously. As I have argued
Caught on Camera: The Inconsistency of Privacy Advocates on Surveillance Technology
In the aftermath of the Boston Marathon bombing, we've seen a lot of discussion about the crucial role that the abundance of surveillance cameras and smartphones played in finding the suspects. The general consensus seems to be that these technologies were useful. For example, New York Mayor Michael Bloomberg said, "The Boston bombing is a terrible reminder of why we've made these investments—including camera technology that could help us deter an attack, or investigate and apprehend those involved." And Chicago Mayor Rahm Emanuel similarly endorsed surveillance cameras when he said, "I will say, as I always have, because we have continued to put cameras throughout the city for security … purposes, they serve an important function for the city in providing the type of safety on a day-to-day basis—not just for big events like a marathon, but day-to-day purposes."
Not surprisingly privacy advocates worry that such a high-profile display of the benefits of these camera systems will lead to more public acceptance and adoption, and so they are trying to minimize the value of these systems by arguing that this is a rare event. Jeff Chester, the executive director of
The Cost of Privacy: Netflix – Three Years & Three-Quarters of a Million Dollars
I've written before about how well-intentioned privacy laws and regulations can come at the expense of innovation and harm consumers (see here, here, and here), but there is not a lot of data available to show the exact impact. However, a new feature on Netflix provides a good case study of the impact on innovation of at least one of these privacy rules.
First, some background. Today, Netflix announced a new feature—"Netflix Social"—which lets users share the TV shows and movies they watch on Netflix with their friends on Facebook. As Cameron Johnson, the director of product innovation, at Netflix explains on the official Netflix blog:
By default, sharing will only happen on Netflix. You'll see what titles your friends have watched in a new "Watched by your friends" row and what they have rated four or five stars in a new "Friends' Favorites" row. Your friends will also be able to see what you watch and rate highly… You are in control of what gets shared. You can choose not to share a specific title by clicking the "Don't Share This" button in the player.
The FTC's Top Consumer Priority Should be Identity Theft
The past two weeks have seen two important announcements come out of the Federal Trade Commission (FTC). First, Commissioner Edith Ramirez was designated to replace outgoing Commissioner Jon Leibowitz as Chairman. Second, identity theft has been reported as the top consumer complaint to the FTC for the 13th year in a row.
Why are these two announcements related? It's simple. As Chairwoman Ramirez considers how she will lead the FTC throughout her term, it's worth looking at where the FTC can help Americans the most, particularly in an era of limited budgets. And the most recent data from the FTC overwhelmingly shows that the top priority for the Commission should be on identity theft.
The latest data on identity theft comes from the FTC's recently released Consumer Sentinel Network Data Book for 2012. The Consumer Sentinel Network (CSN) is a database of consumer complaints received by a variety of sources including the FTC, state law enforcement agencies, state attorneys general, the FBI, the Consumer Financial Protection Bureau, the U.S. Postal Inspection Service, and the Better Business Bureau. While there are limits to how the data should be used


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By Rich TandlerWith the championship competition phase of Redskins 2011 season essentially over, lets take a look at what really matters right now. What pieces of the puzzle for 2012 and beyond are in place? Where will the Redskins have to look for help in free agency and in the draft? Over the next two weeks well put the roster under the microscope and see who might be key members of a playoff team and which ones need to be left on the side of the road.Earlier this week we looked at the offensive line and running backs. Today its the wide receivers and tight ends. Well work our way through the roster by position over the next couple of weeks.Key starters: Fred Davis, Leonard Hankerson
Marginaldepth players: David Anderson, Niles Paul, Terrence Austin, Santana Moss, Logan Paulsen, Chris Cooley, Anthony Armstrong
Out: Donte Stallworth, Jabar GaffneyDavis is on pace to gain a little over 1000 yards on 78 receptions this year, a solid performance considering what a mess the quarterback situation has been this year. His contract is up after this year but it seems to be a pretty good bet that the Redskins will lock him up for the next several seasons.We should be careful about declaring that Hankerson is a future star. The fact that he broke out with eight receptions for 106 yards in his second game as a full-time starter certainly was promising. But with his hip injury well have to press the pause button on this story and see if he can have a true breakout season in 2012. Still, as of right now he looks like a solid building block.It seems odd to see Moss and Cooley listed as marginal players when they have been mainstays for so long. But it seems unlikely that either will be with the team in 2013 and if they are they will be reserve and role players. Moss probably will be around next year for the second season of the three-year contract he signed in August. But he will be 34 in 2013 and if he is here he should be pushed down the depth chart by younger talent. Cooleys future has been discussed and he could be asked to take a pay cut to remain a Redskin next year, when he will be 30.Paul and Austin are late-round draft picks who have an opportunity to get themselves established. We will have to see if they develop beyond special teams and role players and become regular contributors on offense. If one of them does it will be a nice boost; if both do it would be a major plus for the Redskins.There is no reason to think that Paulsen wont continue in his present role as a blocking tight end and special teams player for the next few years. His undrafted free agent contract will keep him under the teams control for the next two seasons at a very reasonable rate.Anderson, 28, is under evaluation. He will suit up for his third game and he may take the place of Gaffney, who is about to turn 31, for the next couple of years. The Redskins would like him to be reasonably productive and step aside if another young receiver is able to step up.Armstrong is off to a slow start following up his nice 2010 season as a 27-year-old rookie. There's no reason not to keep him around to at least compete for a spot in camp in 2012.
Stallworth was released and then recently resigned and it seems unlikely that he will be back next year.Rich Tandler blogs about the Redskins at www.RealRedskins.com. You can reach him by email at email@example.com and follow him on Twitter @Rich_Tandler
Which late-round receivers are keepers?
Which late-round receivers are keepers?
November 25, 2011, 4:47 pm


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Cal 29 Fuel Tank Replacement
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Just acquired a well maintained 1979 Cal 29. However the original 20 gal tank leaks. After inspecting the area dimensions, it seems as if the aft cabin compartment walls need to be removed in order to get the tanks in and out. Does anyone have any first hand experience with this?
In 1999 we had to replace the fuel tank on our, then, 1976 Cal 2-29. Removing the old tank and installing the new required the removal of a portion of the longitudinal bulkhead between the engine compartment and the port quarterberth. One must leave enough of the bulkhead in place around the edges of the cut-out to allow one to install backing plates to the edges of the opening when it is time to reinstall the cut-out. One thing to keep an eye on is he support base for the tank which must be very sturdy. Also, one does not want the tank to rest flush against the transverse bulk-head between the engine compartment and the stern locker or it will be subject to wear and potentially corrosion. We had an approxmately 18 gallon stainless steel tank made up that just fit through the cut-out though that effort was a trial. The 18 gallons gave us roughly 36 hours of running time on our Yanmar 2GM20F engine or a powered range of about 180 miles.
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www.fifi.org Documentation Manpages GNU Info Debian document tree Whole document tree Trigance web page Public services User info Mailing lists Secure server Multilingual usage
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#include <db.h> int DB->get_byteswapped(DB *db);
int DB->get_byteswapped(DB *db);
The DB->get_byteswapped function returns 0 if the underlying database files were created on an architecture of the same byte order as the current one, and 1 if they were not (i.e., big-endian on a little-endian machine or vice-versa). This field may be used to determine if application data needs to be adjusted for this architecture or not.
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Zeb ColterActiveAlso known as Dutch Mantel, Dutch Mantell, Texas Dirt, Wayne Cowan, Uncle Zebekiah, Zebekiah
Latest comments of the CAGEMATCH inmates
Phenomenal91 wrote on 30.08.2014:
[10.0] "It took Dutch 40 years to finally become a high profile wrestling superstar. Although he'd been a great worker in several promotions throughout his seemingly never ending career, Dutch never achieved much in the way of fame as a wrestler. He became better known in the wrestling industry for his work behind the scenes than for his on-camera performances. It's strange that WWE decided to take this former TNA booker who had never been a wrestling legend in the traditional sense and make him one of their top managers. His character's remarks courted mainstream controversy, and gave Dutch/Zeb/Wayne Keown a special kind of notoriety he never could have hoped for a few short years earlier. This is the oddest kind of career resurgence a wrestler can have. But it couldn't have happened to a more deserving guy. Here's to hoping we see Dutch for another 40 years!"
AriesMark wrote on 11.03.2014:
[8.0] "One of the most entertaining and unique managers in the business today. Former wrestler Dutch Mantell has made this character stand out in so many ways. Cuts good promos and is a good mouthpiece for Jack Swagger who really needs one. Cesaro, however I admit does not really need a mouthpiece. Former Vietnam vet paid his dues in the business as both a wrestler and a booker. While he's nowhere near Paul Heyman's level as far as heel awesomeness is concerned, he's still a good mic talker with an interesting, yet controversial Libertarian/Tea Party type gimmick. Eine der unterhaltsamen und einzigartigen Manager in der heutigen Geschäftswelt. Der ehemalige Wrestler Dutch Mantell hat diesen Charakter zeichnen sich in vielerlei Hinsicht. Schneidet gut Promos und ist eine gute Mundstück für Jack Swagger, die wirklich benötigt man. Cesaro, aber ich gebe zu, nicht wirklich ein Mundstück. Ehemalige Vietnam Tierarzt bezahlt seine Beiträge in der Geschäfts sowohl als Wrestler und Booker. Während er ist bei weitem nicht Paul Heyman Niveau so weit wie Ferse awesomeness betrifft, ist er immer noch ein gutes Mikrofon Sprecher mit einem interessanten, noch umstritten Libertarian / Tea-Party-Typ-Gag."
spesini wrote on 01.03.2014:
[9.0] "Really awesome manager, after Paul Heyman best manager currently in WWE. Real Americans without him aren´t Real Americans."
JustinJDMarineau wrote on 25.02.2013:
[9.0] "I never got the chance to follow Dutch Mantel's career when he was in WWF as Zebekiah in the mid-90's managing the likes of JBL and The Harris Brothers. As a matter of fact, all I knew about him was that he was a booker for TNA at one point in time. But ever since he unexpectedly returned to the WWE recently and became Zeb Colter, he has without a doubt made me become a big fan of his! He obviously falls under the category of being such an amazing heel manager if he can take a great talent like Jack Swagger who hasn't done that much within the past 2 years and catapult him to the highest point in his career in such a controversial fashion that he even got people outside of the wrestling world talking about Jack Swagger as well as himself! Zeb Colter has not only done wonders for Jack Swagger's career so far, but for his own career as well! He has a character on WWE TV now that best suits him (being a legit Vietnam veteran) and he has more than the gift of gab to actually pull his character off the way he does and to be a great mouthpiece let alone be an amazing manager in Jack Swagger's corner! WE THE PEOPLE!"
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Andy Kaufman: "Hello, ladies and gentlemen. I'm Andy Kaufman as of course most of you know. Uh, I have a lot of unfinished business in the South. First and foremost in my mind is taking care of that dumb hillbilly, Jerry Lawler. I really wanna take care of him,...Read on!