text:
Credits & Info
- Date
- 03/04/2009
- File Info
- Song
- 44 sec
- Score
- 2.18 / 5.00
Licensing Terms
- Attribution:
- You must give credit to the artist.
- Noncommercial:
- You may not use this work for commercial purposes unless you make specific arrangements with the artist.
- Share Alike:
- If you alter, transform, or build upon this image, you may distribute the resulting creation only under a license identical to this one.
- Score:
- Rated 2.18 / 5 stars
- Plays & Downloads:
- 419 Plays | 54 Downloads
- Share Links:
- Genres:
- Voice Acting - Voice Demo
- None
Author Comments
shandra... i got to tell ya something
for FatKidWithAJetPak's Voice Acting Contest
http://www.newgrounds.com /bbs/topic/1025263
Rated 2 / 5 stars
Well, it seems like you really didnt try for this. It wasnt very good acting at all and the ending just wasnt original. There was only two characters and they both sounded the same. Try to include a longer story with more characters instead of just saying a random 30 second voice clip.
Thanks for entering though. ;) Better luck next time. *Lol whats up with the da dda dum dum da d daaa at the end?*
Dylawrence said:
Suggestions: needs more content, and the characters could seem more real... but the real problem was the story, it needs more depth!
Compliments: fucking awesome punch line!
is that out of 100? whatever. i did actually try, this is just the first time i've ever done anything like this. the "da da dum" part was really the only spur of the moment stuff. i'd like to improve my voice acting and participate in any future contests.
thanks Dylawrence!
Rated 5 / 5 stars
I liked the babey crying in the background LOL. adds a quirky novelty :D:D:D
no its funny. lol. thanks alot. and fingers crossed for the contest! good luck!
stalagmite :D:D:D
thanks man. if you were on of the judges i probably would have ben better off.
fun fact; the baby was actually a door closing. i tried to redo it, but every other take sounded gay.


text:
The visa for Cuba is rather controversial since there isn't much information about it on the internet. So here's my attempt at dispelling all doubts regarding entry requirements into Cuba for Indians.
We travelled to Cuba in January 2012. Since we flew in from Mexico, we were able to purchase what they call a tourist card. This costed us 250 Mexican Pesos (approximately USD 20). The tourist card is available to anyone regardless of nationality. You simply buy it, fill in your details and you're ready to arrive in Cuba. Present it at immigration in Cuba and they'll let you in with a stamp on it. You need to keep this card with you until you leave Cuba.
The tourist card acts as your visa for Cuba.
You can also purchase the tourist card on board most flights to Cuba. If you're flying in from another location, make sure you confirm with the airline that they do indeed have the cards available.
If not, you can also purchase them just before immigration when you arrive at Havana airport.
Just be careful to not make any mistakes while filling in your card. If you make an error, you will need to purchase a new card.
So there you have it. No prior visa is required for Indians (or anyone else) traveling to Cuba. All you need is your passport, USD 20, and the spirit to enjoy a country that is truly unique in this day and age of globalization!
Note: You will have to pay a 25 CUC (25 USD) departure tax when you leave Cuba. Everyone has to pay this at the airport, there are ATMs and currency exchange Cadeca's at the airport – the counter does not accept cards though.

subset: commoncrawl


text:
Promoting an increase knowledge of the profession of athletic training to the citizens of Kansas.
If you are a member of the National Athletic Trainers Association (NATA) then you are automatically enrolled as a member of the Kansas Athletic Trainers Society (KATS). For non-NATA members an application is required for membership to KATS and the fees are $20. Athletic trainers from outside Kansas are welcome to join KATS as well. The same application is required and the fee is also $20.
Click here to fill out the application.
7th Annual Sports Medicine Seminar … Practical Applications for Clinicians
Sunday November 10th, 2013
Maize High School Auditorium
905 W Central
Maize, KS 67101


text:
This feature is not supported on the Wolfram Cloud.
This feature is not supported on the Wolfram Cloud.
represents a button that is labeled with label, and evaluates action whenever it is clicked.
Details and OptionsDetails and Options
- label can be any expression, including a dynamic one. »
- Button by default displays label in style, which typically uses the system button font.
- Button[label,action] maintains action in unevaluated form, evaluating it each time the button is clicked.
- The following options can be given:
Alignment Automatic how to align contents within the button Appearance Automatic the overall appearance of the button AutoAction False whether to click the button automatically when the mouse is over it Background Automatic button background color BaselinePosition Automatic alignment relative to surrounding text BaseStyle "GenericButton" base style specifications for the button ContentPadding True whether to shrink the margins tightly around the contents Enabled Automatic whether the button is enabled or grayed out Evaluator Automatic the kernel in which to evaluate expr FrameMargins Automatic minimum margins to leave inside the frame ImageMargins 0 margins around the image of the displayed button ImageSize Full the overall image size of the displayed button Method "Preemptive" the evaluation method to use Tooltip None the tooltip for the button TooltipDelay 0.` how long to delay before displaying the tooltip TooltipStyle {} style specifications for the tooltip - With the default setting ImageSize->Full, a button will be sized to fill out its enclosing region in a Grid or related construct.
- The setting ImageSize->Automatic specifies that the button will be sized to fit its contents, but will not expand to fill out an enclosing region.
- Settings of Tiny, Small, Medium, and Large for ImageSize specify buttons with certain system-standard minimum sizes.
- Typical possible settings for the Appearance option include , , , and . In some cases, , , etc. are also supported.
- Appearance->"Pressed" gives a button with a pressed appearance. Appearance->{type,"Pressed"} gives a button of a certain type with a pressed appearance.
- With Appearance->None, label is displayed literally, without being placed in a button. »
- Typical possible settings for the Method option include and .
- With the default setting Method->"Preemptive", button actions are performed immediately, preempting any other evaluation, but are allocated only a limited time to complete.
- With the setting Method->"Queued", button actions are added to the current queue of evaluations, and are performed when other evaluations are complete. No time limit is applied.
- The settings for BaseStyle are appended to the default style typically given by the style in the current stylesheet.
- Button[label] displays as a button labeled with label, but performs no action.
- Button[prims,action] can be used within graphics objects to specify that action should be evaluated whenever the graphics primitives prims are clicked. »
- Button[label,None,BaseStyle->stylename] inherits button functionality from the definition of stylename in the stylesheet. Such styles typically allow \[SelectionPlaceholder] to be used in label to represent the currently selected text.
- Some style names defined in default stylesheets that provide Button functionality:
"Paste" effectively use NotebookApply upon the current selection using the button label as the applied data "Evaluate" use NotebookApply and SelectionEvaluate in sequence upon the current selection "EvaluateCell" use NotebookApply upon the current selection, then evaluate the entire cell containing the selection "CopyEvaluate" equivalent to , but paste the result into a new cell instead of changing the currently selected cell "CopyEvaluateCell" equivalent to , but apply changes to a newly created copy of the input cell instead of changing the currently selected cell
ExamplesExamplesopen allclose all
Basic Examples (1)Basic Examples (1)
Create a button that prints a number:
In[1]:= |
Out[1]= |
Introduced in 2007
| Updated in 2010 (8.0)
© 2015 Wolfram. All rights reserved.


text:
looking for ancestors for charles elmer martin's wife alice (davis) martin
Journal by
i have some info on charles: who his parents are and his siblings; however iam having some problem with info on his wife, alice.
i'm not sure but her parents (davis) could be from Iowa - her father's name could be roy davis
is there anyone out there that could tell me anything?
catherine wilkinson
by nannycathy Profile | Research |
Contact | Subscribe | Block this user
on 2008-12-16 02:08:20
on 2008-12-16 02:08:20
nannycathy has been a Family Tree Circles member since Dec 2008. is researching the following names: MARTIN, CHARLESEMARTINALICEMARTIN, ALICEMARTIN and 1 other(s).


text:
- March 31st, 2011
- /
- General Info, In the News, Legal Services, New York Law
- /
- 1 Comment
- /
- New York Cuts Funding to the Courts Undermining Justice and Hurting the Most Vulnerable New Yorkers
The New York State budget passed in the overnight hours cuts $170 million from the court system that will result in hundreds of layoffs and longer waits for trials. The state's chief judge, Jonathan Lippman, told the New York Times that the cuts "would require hundreds of layoffs." He said, "It will have a tremendous impact on the system…you're going to see delays in the administration of justice, without question."
The cuts will hurt anyone who is depending on the court system for justice and weakens the State's basic promise of delivering justice for all New Yorkers. Any time the government makes a change, it creates winners and losers: in this case, the losers are the poorest New Yorkers who will feel the brunt of these cuts and the employees who lose their jobs. The winners? Count the civil court defendants who avoid justice and the insurance companies that avoid paying compensation to injured New Yorkers.
And what savings will these drastic cuts produce? .1 percent of the total state budget. That's right: these savings will result in a savings of one tenth of a penny for every hundred dollars spent. Does anyone believe that is what New Yorkers would want? In return for a potential savings of .1 percent on their tax bills, would New Yorkers undermine the judicial system?
The Impact of the Budget Cuts in the Courthouse
Chief Justice Lippman has not announced the specific cuts that he will make, but he must reduce the Court budget by $170 million. We can expect cuts to the following personnel:
- Court Clerks: These are the people who handle the paperwork of the courts. Without them, it will take longer to process cases, meaning fewer cases can be heard each day and cases will take longer to come to trial.
- Court Officers: These are the people who provide for safety and order in the courts and the courthouses. They staff the doors and the magnetometers. If you reduce personnel there, you will see longer lines just to enter the courthouse. If they reduce court officers in the courtrooms, fewer hearings can be held at the same time, resulting in more backlogs.
- Law Secretaries: These are the people who help the judge prepare orders and decisions, do research for the judges and provide general legal support. Without them, judges can handle fewer cases and will take longer with the cases they do have.
- Hearing Officers: We already know that the court system plans to eliminate virtually all of the hearing officers. These are retired judges who would help move cases along by handling jury selection and attempting to resolve cases by negotiating plea bargains and settlements so not every case required the time and money of a trial. The Daily News points out that many of these hearing officers were esteemed judges whose talents and wisdom will now be lost. "Everything is just going to take longer," said Justice Jeremy Weinstein, who oversees the civil courts in Queens. "There's just no way around it."
The Impact of the Budget Cuts on the Judicial System: Justice Delayed is Justice Denied
These cuts will not be minor or superficial; they will affect the ability of the courts to operate. In criminal cases, it will take longer for a defendant's case to come to trial. That means innocent defendants may sit in jail longer for crimes they did not commit. As backlogs develop, the jails will fill up, straining overcrowded local jails. The cuts to the court system will reduce State spending, but backlogs in the jails will cost New York City and the counties. An overflowing jail already required Suffolk County to build a new jail. Therefore, the State lawmakers will save a few bucks while costing local governments more. Taxpayers keep paying.
In civil cases such as the personal injury and medical malpractice cases that I handle, we can expect growing backlogs in bringing a case to trial. For example, once a case is certified ready for trial (by filing a Note of Issue) in the Bronx today and added to the trial calendar, it can take 18 months for that case to come to trial. With these budget cuts, we can expect that to grow to 24 months and increase to as high as 36 months. In Suffolk County, the delay will grow from 12 months to 24 months or more. The delays will grow because of the loss of court personnel, particularly the hearing officers who helped resolve many cases before they went to trial, yet those cases will now go to trial.
The cuts and delays may have another impact on plaintiffs seeking justice. As the wait for a trial increases, insurance companies may become less willing to settle cases early. After all, if they can wait three years before making a payment, why pay now? If insurers settle fewer cases early, that will delay justice for plaintiffs and further add to the backlogs in the courts.
The Budget Cuts Hit the Poor the Most
As is too often the case, these budget cuts will hurt the poor the most. The poor criminal defendant is less likely to have the money to post bail and so will sit in jail longer waiting for a trial. The poor person injured due to the negligence or recklessness of another will wait longer to receive compensation. If the person cannot work due to an injury caused by the negligence of another and cannot receive timely compensation, it may mean going without an income. If the person lacks health insurance and needs medical treatment due to the negligence of another, it may mean going without medical care.
The delays may undermine cases of the poorest plaintiffs. If a poor plaintiff requires medical attention for an injury caused by another's negligence and lacks health insurance, the insurance company will use the lack of treatment to argue against making any payment or to reduce a settlement amount or payment. If a person's life is threatened by medical malpractice or shortened by it, a delay in bringing a case to trial could me that the person could die before ever receiving justice.
I understand the desire of the State leaders to rein in spending. I understand the claim that everyone has to share in the cuts. Yet I wonder how New Yorkers feel about making these cuts. The savings from the court budget will undermine justice in this state, yet those savings account for .1 percent of the entire state budget. What cost justice? Our State leaders have answered the question.
I welcome your comments.
Carol L. Schlitt
New York Personal Injury Attorney


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text:
Scripture: Matt. 18:12-14; Luke 15:1-7;
John 10:1-18
Click on the visual to download and print the original document
Display for lesson: on a table
set up a field (green fabric) with rocks, shepherd and sheep. Put a couple
together and one far away looking lost & trapped in rock and shrubs.
Preview: We have talked about parables the last couple of
weeks. A parable is an earthly story with a heavenly meaning that Jesus taught.
There were 3 main jobs for men during the time of Jesus. They
were shepherding, fishermen and farming. So Jesus is going to use a lesson that
they will understand.
Jesus told the parables of the lost sheep, the lost coin,
and the Prodigal son at the same time to these people wanting to listen. We did
the Prodigal Son last week and we are going to talk about the lost sheep and the lost coin today.
The Bible tells us that Jesus is the Great Shepherd. Jesus, like
shepherds, is always watching over us. Shepherds protect their sheep, and
always want to make sure they return home safe.
Lesson: One of the parables Jesus told was about a
lost sheep. Jesus wanted to show that God loves everyone and is happy when
anyone repents. God wants everyone to go to Heaven. There were people in the
time of Jesus who thought they were better than every else. We have people like
that now. When they all came to see Jesus, the
Pharisees and the scribes started complaining that Jesus welcomes sinners…He
even eats with them!
So Jesus told a parable about a shepherd. He said that
if any man had 100 sheep and he lost one of them, wouldn't he leave the 99 in
the wilderness to go find the one that is lost until he finds it? So, if we
quit coming to worship and start doing things that God doesn't like, then we
are lost.
When the shepherd finds the lost sheep, wouldn't he
lay it on his shoulders and celebrate that he found it? When he gets home, he
would call together his friends and neighbors saying to them "Celebrate with me
because I have found my lost sheep!"
Jesus said just like the
found sheep, when a sinner repents, there is more joy in heaven than over the
99 who do not need to repent.
Who is the Shepherd? Jesus
is the GREAT Shepherd
Who is watching over us? Jesus
Who is the lost sheep? the
ones who are not faithful to Jesus
I found this Shepherd's Hook at a Halloween store.
(This is in pieces, and you screw the plastic pieces together to make it the 68".)
The sheep would usually graze
all day, then be kept in caves or pens at night. They usually had one opening,
and if it didn't have a door to block, the shepherd would lay in front of the
opening to sleep at night to protect the sheep. Several flocks of sheep could
be kept together, and in the morning if a shepherd called for his sheep, they
recognized his voice. Jesus said that He is the gate for the sheep. He protects
from thieves and robbers. He takes care of His people like a shepherd and would
check the sheep at night when they came in for injuries and fix with oil if
In the New Testament book of John, Jesus told the
people about a shepherd and his sheep. Jesus said, "I
am the good shepherd. The good shepherd gives His life for the sheep." {Today's Bible verse} Which Jesus gave His life for us by
dying on the cross.
This can printed in color or black and white to use as a picture to color. You can print them here:
Put on coin headbands. (See directions at the bottom) I walked around the
room with a broom and a candle 'looking' for my lost coin.
Parable of the
lost coin: Open your Bibles to Luke 15:8-10. We are going to read this parable.
This parable is only 3 verses, but very important.
There was a woman that had a headband that
had 10 silver coins on it. She probably got it on her wedding day.
One of the coins fell off and was lost.
She lit a lamp, swept the entire house, corners and all, to search carefully for the lost coin. She looked and looked for the lost coin... She didn't stop looking until she found that lost coin!
One of the coins fell off and was lost.
She lit a lamp, swept the entire house, corners and all, to search carefully for the lost coin. She looked and looked for the lost coin... She didn't stop looking until she found that lost coin!
When she finally found it, she called her friends
together to celebrate that she had found the coin that was lost. Even though
she had 9 other coins, she looked carefully until she found the lost coin.
Jesus wanted the
people to understand that for those that are lost, Jesus will welcome you back
and rejoices when you return.
For hands on fun, I made 1 ½ inch
round circles on grey cardstock (Cricut machine, George, shadow blackout O). I
punched a hole with a hole punch and used yarn (or whatever you prefer) to tie 9 'coins' on a long piece
of fabric for a headband. (I used stretchy fabric that would not fray.) I left an open space for the 10th. (I put 3 on, left a space, then added the final 6 coins.)
I hid extra 'coins' around the room and let them search and they added the 10th coin that they found with a safety pin. They had so much fun looking for the coins!
I hid extra 'coins' around the room and let them search and they added the 10th coin that they found with a safety pin. They had so much fun looking for the coins!
You can print this worksheet here.
There are 2 lapbook printables for today's lesson. You can print them here:
This is the printable for today's lesson. The students will cut out the shepherd and glue him to the worksheet. You can print it here.
You can find all the download links for the Life of Jesus lapbooks and the lapbook worksheets here.
Lost Coin visuals found here.
and are the copyright of FreeBibleimages.org. (Used with permission)
Lost sheep visuals for this post are here. (Original publisher)
Scripture taken from the New King James Version®. Copyright © 1982
by Thomas Nelson.
Used by permission.


text:
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will be back with more photos after I get through the 300+ photos oscar took with the camera.
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Top Definition
A grueling physical workout intended to make you a better athlete. Usually done at home or the gym, and we call that place the "pain cave."
"If I want to get faster on the bike, I've gotta do my workout, so I am headed to the pain cave."
Por Chumango
08 de febrero de 2010
3 more definitions
A situation that involves either performing tasks for or working with people you do not like.
Question: "How was work today?"
Answer: "It was a total pain cave..."
Answer: "It was a total pain cave..."
Por Male Nurse
25 de junio de 2009
A mentally and/or physically debilitating condition worse than a hang over usually brought on by the consumption of copious amounts of alcohol combined with severe lack of sleep.
... oh my head... it's a day in the pain cave for me today, thanks to that goddamn moonshine!
Por 00s4s00
15 de noviembre de 2009
Dark room or basement where you lure unsuspecting and intoxicated women.
Come into my pain cave so I can bludgeon you.
Por The Pantsman
03 de mayo de 2007


text:
Tag Archives: sojourner
me interviewed for the library school newsletter I used to edit in 1993
When I went to the Graduate School of Library and Information Science at the University of Washington, there was a newsletter called the Sojourner. I was the editor my first year. It was a print newsletter. Now the newsletter is … Continue reading
Posted in me!
Tagged gslis, interview, ischool, jessamyn, newsletter, silverfish, sojourner, uw
Comments Off


text:
Since genetic engineering has the potential to alter the uses to which domestic animals are put, it also can lead to fundamental changes in the relationship between (1) individuals of the same species or population, (2) different species, (3) engineered animals and their products, and (4) the products and humans. There currently are major research efforts underway to develop the use of genetically engineered animals as sources for production of nontraditional materials for human use. Such uses can be divided into three major categories: biopharmaceuticals for animal or human use; live cells, tissues, and organs for xenotransplantation; and raw materials for processing into other useful end products (the latter use is discussed in Chapter 4). Several possible concerns that might in practice arise from the first two uses are discussed in the following sections.
A large number of genes encoding useful protein products—hormones, blood proteins, and others—has been introduced into domestic animals, leading to their expression in milk, eggs, or blood (Dove, 2000; Table 3.1). So far, none of these animals has been used for commercial production. However, a recent report suggests that the same technology might be extended to the large-scale
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Animal Biotechnology: Science-Based Concerns
Animals Engineered for Human Health Purposes
Since genetic engineering has the potential to alter the uses to which domestic animals are put, it also can lead to fundamental changes in the relationship between (1) individuals of the same species or population, (2) different species, (3) engineered animals and their products, and (4) the products and humans. There currently are major research efforts underway to develop the use of genetically engineered animals as sources for production of nontraditional materials for human use. Such uses can be divided into three major categories: biopharmaceuticals for animal or human use; live cells, tissues, and organs for xenotransplantation; and raw materials for processing into other useful end products (the latter use is discussed in Chapter 4). Several possible concerns that might in practice arise from the first two uses are discussed in the following sections.
A large number of genes encoding useful protein products—hormones, blood proteins, and others—has been introduced into domestic animals, leading to their expression in milk, eggs, or blood (Dove, 2000; Table 3.1). So far, none of these animals has been used for commercial production. However, a recent report suggests that the same technology might be extended to the large-scale
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production of vaccines (Stowers et al., 2001). Such "biopharming" applications have the potential to use well-established agricultural methods to produce large amounts of valuable products at relatively low expense as compared to fermentation. Although the end products of these applications will be novel, by and large, the process of production and the potential concerns are not likely to differ greatly from those seen in current practice, such as the use of animals or animal cell cultures to prepare live vaccines (Brown et al., 2001), hormones, or traditional products such as meat, milk, or leather. These standard products are subject to specific regulatory procedures, and essentially the same regulatory framework is expected to apply for products of both biopharming and standard technology as regards common issues such as purity of the final product, microbial contamination, levels of adventitious DNA, and the like. Nevertheless, a few more specialized concerns arise.
Contamination or Spread of Novel Pathogens
As discussed in Chapter 2, there is a theoretical potential for microorganisms to acquire—by recombination or transduction—genes from the vector constructs used to insert the transgene. Although there is no example yet of acquisition of any gene, including drug resistance markers, by bacterial flora living in a transgenic animal, the spread of introduced genes remains a possibility, albeit remote.
Of greater concern is the possibility for generation of potentially pathogenic viruses by recombination between sequences of the vector used to introduce a transgene and related, but nonpathogenic, viruses that might be present in the same animal. These concerns are particularly acute for retroviral vectors. Retroviruses appear to be efficient vehicles for inserting transgenes into many species, including chickens (Crittenden and Salter, 1990; Briskin et al., 1991), mice (Jahner et al., 1985), cattle (Chan et al., 1998), fish, and shellfish (Sarmasik et al., 2001), and might prove more successful than pronuclear injection of DNA in the generation of transgenic offspring. In many species, including chickens and pigs, there are endogenous proviruses (including the porcine endogenous viruses, PERVs, discussed below) that are competent for low-level replication in the host animal, but have no apparent pathogenic consequences (Boeke and Stoye, 1997). Endogenous proviruses are DNA sequences that were derived from infection of germline cells with a retrovirus and that are transmitted from parent to progeny like any normal gene. Their attenuation relative to their exogenous, pathogenic counterparts often is due to differences in transcriptional regulatory sequences in long terminal repeats (LTR's; Rosenberg and Jolicoeur, 1997). Since many vectors, such as the widely-used ones derived from murine leukemia virus (MLV), have LTR sequences derived from pathogenic viruses, the presence of both vector and
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endogenous provirus in all cells of a transgenic animal provides the potential for generating pathogenic recombinant viruses by straightforward and well-understood mechanisms. Such concerns are particularly acute in chickens and pigs, where infectious proviruses very similar in sequence to those used for vectors are known to be present (Boeke and Stoye, 1997). In mice, there is a well-studied model in which recombination between benign endogenous proviruses or endogenous proviruses, and infecting viruses early in the life of the animal, can cause a high incidence of lymphoma (nearly 100 percent in some mouse strains) 6 months later (Stoye et al., 1991; Rosenberg and Jolicoer, 1997). Given this example, it is reasonable to expect that viruses of much greater pathogenicity are likely to arise in an animal when there is a possibility of recombination between vector and endogenous viral sequences.
Similar concerns arise with the use of vectors based on lentiviruses for the introduction of genes (see Chapter 2). Recombination of lentiviruses in circulation in domestic animal populations, such as Feline Immunodeficiency Virus (FIV) in cats and Bovine Immunodeficiency Virus (BIV) in cattle, with vectors based on Human Immunodeficiency Virus (HIV) is improbable due to the large genetic distance between them. However, vectors based on FIV and BIV are being developed (Curran et al., 2000; Berkowitz et al., 2001), and their use to introduce transgenes into the corresponding species would significantly increase the probability of generating more pathogenic recombinants.
TABLE 3.1 Potential uses of transgenic animals for pharmaceutical production.
Theoretical Yield (g/yr of Raw Protein)
Examples of Products Under Development
Monoclonal antibodies
Growth hormone
Human serum albumin
Superoxide dismutase
Growth hormone
Antithrombin III
Tissue plasminogen activator
Monoclonal antibodies
Growth hormone
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Factor VIII
Factor IX
Human serum albumin
Source: Modified from Dove, 2000.
Ensuring Confinement of Unwanted Animals
Although biopharm animals are not intended for consumption by humans or other animals, there are grounds for concern that adequate controls be in place to ensure that this does not happen without appropriate approval (see Chapter 4). As long as they do not contain the product of the introduced gene, there might be no strong reason to believe that eating or using products from transgene-containing animals would pose a threat to human health; the possibility of such a threat combined with the lack of regulatory oversight for such uses argues strongly for confinement measures.
Although it has been stated that such animals will be too valuable to the owners to allow their misappropriation (Wall, 2001), the fact that the products of interest usually are produced only by lactating females means that half the transgene-containing animals essentially will be valueless, as will the females at the end of their period of useful production. "No takes," or animals generated from manipulated embryos, but culled because of lack appropriate expression of the transgene product (or lacking the transgene itself) also are inevitably generated in significant numbers during the production of transgenics. Thus, companies using biopharm animals are likely to seek approval for marketing food or rendered products from surplus animals, and the regulatory agencies will need to be ready to deal with such requests. Of greater concern is the possibility that surplus animals (and their carcasses) might, through inadvertence or theft, find their way into the food or rendering chain, or be used for breeding, thus allowing uncontrolled spread of the transgene into the general population. This would create a regulatory problem of dealing with unapproved transgenes after their release into the food chain—a problem analogous to that posed by the appearance in food products of Starlink, a transgenic maize unapproved at the time for human consumption (Fox, 2001).
Xenotransplantation differs from other uses of genetically engineered animals in that it has the potential to create something entirely new—permanent
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human–animal chimeras—in which cells of distantly-related species survive and function for long periods of time in the most intimate contact possible. Given its potential for alleviating human diseases due to irreversible tissue or organ failure (Table 3.2), and given the acute shortage of human organs for transplant, there are very active research programs underway, in both commercial and academic laboratories, to overcome the significant immunologic and physiologic barriers, and thereby to bring xenotransplantation into standard medical practice. This topic and associated concerns about infection have been reviewed in great detail elsewhere (Boneva et al., 2001), and only an overview is given here.
At present, the only animal under serious consideration as a xenotransplant donor is the pig. For regulatory purposes, human cells cultured ex vivo with the cells of any other animal, such as mouse cell lines, also are considered to be xenotransplants (DHHS, 2001); co-cultivation with mouse cell lines has been used in the preparation of some cultured skin grafts as well as human stem cell lines; Thomson et al., 1998). While nonhuman primates, such as the baboon, would seem to have physiologic and immunogenetic advantages such as the lack of a hyperacute immune response, their scarcity as well as the difficulty of clearing them of adventitious infectious agents (as well as ethical concerns) render them impractical for further consideration.
The field of xenotransplantation covers a great many procedures, ranging from implantation of single cells to treat Parkinson's disease and tissues, such as pancreatic islets, to treat diabetes; extracorporeal use of intact organs, such as perfusion of patient blood through pig livers to provide short-term support in cases of liver failure; to transplantation of whole organs—heart, kidney, liver, and so on. While whole-organ xenotransplantation remains far in the future, development of the simpler modalities is underway, and hundreds of human
TABLE 3.2 Applications of xenotransplantation.
Organ Failure
Pig heart, kidney, liver, etc.
Acute liver failure
Extracorporeal perfusion
Pancreatic islets (or cells)
Parkinson's disease, Huntington's Disease, Focal epilepsy, Stroke
Neural tissue
Burn, Skin injury
Skin autograft
(co-cultured with mouse cells)
Note: 0=No successful experience.
1=Some trials have been performed.
2=Successful trials have been performed.
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subjects have received porcine cells or tissues as part of clinical trials in the United States, Russia, Israel, and many European countries (Paradis et al., 1999). Given the nature of infectious disease issues, regulatory concerns are not limited to the United States alone, but extend to the international health community as well.
The development of xenotransplantation as a part of clinical practice promises great benefits in terms of making possible essentially infinite supplies of replacement tissues and organs where severe shortages exist today. This development naturally will entail both great potential benefit as well as considerable risk to the study participant, but such risk is not qualitatively different from that entailed in the development of any other new medical procedure and will not be considered further. The principal concern is that the uniquely close relationship created between recipient and host will allow novel opportunities for transmission of infectious disease, and possible creation of new disease agents in the process. While the history of close contact between humans and pigs is a very long one, and one would imagine that all possible transmission of infectious agents between the two species already would have been seen and thoroughly studied, it is possible that the "co-culture" environment of a transplant would be qualitatively different in ways that would allow different outcomes. Two different types of agents are discussed separately.
Exogenous Infectious Agents
In general, bacteria and parasites that might cause problems readily can be excluded from source flocks, leaving viruses as the principal concern (Onions et al., 2000). As can be seen in Table 3.3, the number of viral agents that are of potential concern is very large. Not all of the viruses are on the list because of their potential to cause human disease; some would cause serious disease among the donor animals and others are sensitive indicators of breaks in biosecurity, and so forth. In principle, since all of theses agents are horizontally (one animal to another) or vertically (mother to offspring) transmitted, they can be eliminated by proper management—proper containment, vaccination, close monitoring, culling, birth by Caesarian section, etc. In practice, elimination is going to prove a very difficult task, since the numbers of agents are very large and there is a lack of reliable assays for detecting many of them. Nevertheless, problems resulting from transmission of exogenous infectious agents are not qualitatively different from the present situation with human donors (allotransplantation), where infection with agents transmitted with the transplanted organ (such as Epstein–Barr virus and cytomegalovirus) is a major problem. In fact, it is anticipated that reduction in the risk of acute morbidity
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TABLE 3.3 Exogenous pig viruses of concern in xenotransplantation.
Foot and mouth disease
Enterovirus 1 Talfan/Teschen
2, 5
Enterovirus (other serogroups)
Enterovirus swine vesicular disease
Human enteroviruses
Enteric calicivirus
Swine hepatitis E
Porcine astrovirus
Western encephalitis
Eastern encephalitis
Venezuelan encephalitis
Japanese B encephalitis
Louping Ill/TBE complex
Wesslebron disease
Dengue fever
West Nile fever
Classical swine fever (hog cholera)
Bovine viral diarrhoea
Border disease
Transmissible gastroenteritis
4, 5
Porcine respiratory coronavirus
4, 5
Epidemic diarrhea
4, 5
Haemagglutinating encephalomyelitis
4, 5
Porcine reproductive & respiratory disease syndrome
4, 5
Porcine torovirus
Murine parainfluenza virus type 1 (Sendai)
Parainfluenza 2
Parainfluenza 3
Blue eye disease
Vesicular stomatitis
2, 5
Influenza A
Influenza C
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1, 5
1, 5
1, 5
Lymphocytic choriomeningitis
1, 5
Reovirus 1 to 3
Rotavirus A, B, C, E.
Porcine picobirnavirus
Porcine endogenous
Hepatitis B
Porcine circovirus
Porcine parvovirus
4, 5
Porcine polyomavirus
Porcine genital papillomavirus
3, 5
Porcine adenovirus serotypes 1 to 4
Porcine cytomeglovirus
Porcine lymphotropic herpesvirus type 1
Porcine lymphotropic herpesvirus type 2
1, 5*
1, 5*
African swine fever
NOTE: 1=Zoonotic.
2=Replicates in human cells or weak evidence for zoonotic potential.
3=Might undergo abortive replication and possibly oncogenic replication.
4=Belongs to a family with evidence of frequent changes in host range or pathogenicity.
5=Undesirable as indicates a breakdown in biosecurity and/or might compromise health of the pigs.
*=Although the virus has not been detected in pigs, it has been included for reasons such as its wide host range.
Source: Onions et al., 2000. Courtesy of D. Onions.
and mortality resulting from the transmission of infectious agents with transplanted organs will be a significant benefit of xenotransplantation.
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Porcine Endogenous Retroviruses
PERVs present quite a different situation and level of concern since they are inherited as part of the host genome and, therefore, cannot be removed easily from donor animals. All pigs contain multiple (around 50) PERV proviruses in their genome, at least several of which encode infectious virus. PERVs are gammaretroviruses, closely related to MLV, that can be classified into three subtypes, A, B, and C, based on their envelope gene sequences (Takeuchi et al., 1998). Subtypes A and B can infect many types of human cells in culture. Subtype C is much less infectious for humans. Most breeds of pig carry proviruses capable of yielding infectious virus of all three subtypes. Although most pigs carry about the same number of proviruses in their DNA, there is considerable diversity in location, implying that their insertion into the genome must have occurred rather recently (on an evolutionary time scale). Based on extensive experience with related endogenous proviruses of mice, it is highly likely that the majority of proviruses contain some sort of genetic defect, and that only a small number are responsible for release of infectious virus. Taken together with the polymorphism in the presence or absence of specific proviruses, it might well be possible to breed animals lacking infectious proviruses for use as xenotransplant donors.
PERVs have not yet been shown to cause disease (or even viremia) in pigs or any other species in which they have been detected. Nor has their presence been detected (by polymerase chain reaction, PCR, or serology) in more than 150 human recipients of pig cells or tissues (Paradis et al., 1999), although a low level of infection of recipient cells can be observed in immunodeficient mice transplanted with porcine islets of Langerhans (Van der Laan et al., 2000). Nevertheless, given the release of viruses infectious to human cells by many types of pig cells; the close similarity of these viruses to viruses known to cause cancer, immunodeficiency, and other diseases in mice and cats; the well-known adaptability and variability of retroviruses; and the example of the rapid worldwide spread of HIV and AIDS, there is serious concern that the novel association between pig and human tissues might create novel evolutionary opportunities for the virus, leading to the appearance of a new pathogen. Although such a pathogen could have serious long-term adverse consequences for the transplant recipient, this issue is not an area of concern since it is far outweighed by the potential benefits of the transplant. The real issue of concern is that the xenotransplant setting might provide the opportunity for the virus to evolve into a pathogen that also could be transmitted from one individual to another efficiently enough to create a new epidemic disease.
Such an evolutionary pathway would require a series of events, each increasingly improbable, as indicated by the scale shown in Table 3.4 (J. P. Stoye, 2001). As implied by the table, it is virtually certain that many cells in the transplant would express infectious PERV following transplantation, and it
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is likely that some local infection of host cells would occur. The subsequent events necessary for generation of pathogenic, transmissible viruses increasingly are unlikely, but on some unknown, arbitrary scale. Although the probability of inadvertent creation of a new epidemic generally is judged to be extremely small (particularly given the long history of intimate association between humans and pigs), it cannot be ignored altogether. Current FDA policy is to permit xenotransplantation trials to proceed, but to require close monitoring of recipients, and (insofar as possible) of their contacts (DHHS, 2001). Attempts also are being made to identify specific proviruses responsible for production of infectious virus and then to selectively breed them out of lines of animals to be used as transplant donors (Herring et al., 2001).
TABLE 3.4 Theoretical scale of risks associated with PERV transmission from xenotransplants.
Cumulative Probability
Expression of infectious virus
Localized infection of host cells
Spreading infection in the host
Persistent viremia
Disease (e.g., lymphoma, "AIDS")
Transmission to close contacts
Spreading, epidemic transmission


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ECEBC's History
The Early Childhood Educators of British Columbia (ECEBC) is the association of educationally qualified individuals who work with children in early childhood settings in the province of BC. The association changed its name from the British Columbia Preschool Teachers Association (BCPSTA) to ECEBC in 1988.
BCPTSA was established in 1969, with its first constitution written and adopted by the membership at its first Annual General Meeting (AGM) on May 23, 1970. In a series of interviews in 1997 of the Association's past presidents, Joyce Brown (the first president of BCPSTA) told the story of a small group of preschool teachers and daycare workers who came together to both support preschool teachers and to work toward better educational preparation. She described how "children needed something better and teachers needed to know what that 'better' was...teachers...were out there working on their own in isolation." Joyce described how she "...never felt we reached that level of teachers feeling their own professionalism. That just was always a fire in my heart...that this should be a profession because it was such important work!"
The preamble to the Constitution at the time, spelled out the rationale for the formation of the organization and its purposes:
BCPSTA (1969) In recognizing there are thousands of BC children in preschool and in daycare centres, In knowing that there are hundreds of teachers involved in teaching these children, In believing that these teachers of young children need support, encouragement and unification throughout BC, We hereby seek to build together this Association dedicated to the varying interests of preschool teachers who serve young children and the community in which they live.
One of the earliest issues faced by BCPSTA was the name it had chosen for itself to represent workers in the preschool and daycare system. Both government officials and public school teachers resisted its efforts to call its members "teachers". Hannah Polowy, the second president of BCPSTA, argued that "people that work with young children whether they are daycare or whatever...they are teachers. They are teaching every minute they are with children!"
Issues that faced later Association presidents and their boards were not unlike the issues faced today. In an article for the provincial government's magazine People in 1975, Kay Britton (President, 1974 to 1976) stated:
"We are determined that the children entrusted to us shall be housed in quality facilities that meet the children's and teacher's needs... We are determined that our salaries shall rise above the poverty level... We are determined that support services for children, parents, and teachers should be available immediately on request. Too many of us have seen one or two years go by with nothing, except the teacher's efforts, being extended to help and rehabilitate a child in need..."
Over the past forty years, ECEBC has focused much attention on promoting professionalism and improved educational preparation for its members, as well as on the development of professional support and resources to improve the quality of early childhood experiences for the children with whom they work. While ECEBC has worked diligently on behalf of its members, benefits have also extended to everyone working in the early childhood field.
BCPSTA was an invited contributor to the DACUM (Developing a Curriculum) process in 1978 that resulted in guidelines for our post-secondary early childhood programs. In 1979, the Association was invited to sit on the newly established Provincial Child Care Facilities Licensing Branch Advisory Committee, and in 1982 on the Early Childhood Education (EC) Articulation Committee. Shortly thereafter, ECEBC maintained membership on the EC Articulation Committee, had several presidents sit on the Provincial Child Care Council (set up by the provincial government in 1994), and successfully led numerous contracts to research educational needs of practitioners (Blueprint, 1992), revised the ECEBC Code of Ethics (1994), and undertook several projects and contracts between 1989 to 2002 to advance the field's professional status through self-regulation. Self-regulation would allow the profession to determine entry requirements to the field and provide direct input into the approval of post-secondary early childhood programs.
ECEBC has held conferences annually since 1970, with the exception of 1984 and 2000. The first three conferences were held in the Lower Mainland. Beginning in 1973, with Focus on the Teacher in Kelowna, locations alternated from outlying Branches to the Lower Mainland. In 1990, Expanding Horizons held at Vancouver's Westin Bayshore was the start of a new trend. The numbers of delegates attending conference had grown so quickly that conference facilities outside of the Lower Mainland were unable to provide adequate facilities. Moreover, ECEBC was becoming increasingly dependent on conference revenue to meet increasing organizational costs. With the exception of Together: 25 Years of Stories in Whistler in 1995 and Together: Valuing the Early Years in Victoria in 1998, this trend continued until the early 2000's.
BCPSTA/ECEBC has been through many changes since its inception in 1969. Membership has grown from 118 members in its first year to over 500 in 1982. Membership numbers continued to grow until 1987 when a sudden drop occurred, bringing membership down to 357. Numbers increased to 2013 under the direction of our first Executive Director Joyce Branscombe in 1996, followed by another slow decline. Since 2002, membership numbers have hovered between 800 and 1300. The challenge of membership is thought to be largely the result of the low wages typical of Early Childhood Educator work. Though every effort is made to keep membership fees low, the challenge continues to be a struggle between keeping fees affordable and meeting the demands of a vital, growing organization.
ECEBC Historical Timeline
Joyce Brown (1970-1972) Hannah Polowy (1972-1974) Kay Britton (1974-1976) Bridie McIlwraith (1976-1980)
Diane Tannahill (2002-2004) Amy Collum (resigned mid-term 2004-2005) Diane Tannahill (mid-term 2004-2005 to 2006) Toni Hoyland (2006-2008) Vi-Anne Zirnhelt (2008-2010) Denise Marshall (2010 - 2013) Taya Whitehead (2013-Present)
Early Childhood Educators of British Columbia 2774 East Broadway · Vancouver, BC V5M 1Y8 Phone: (604) 709-6063 · Toll free: (800) 797-5602 · Fax: (604) 709-6077 · Email: membership[at]ecebc.ca


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WHAT YOU NEED: - Glue gun - A cassette tape that you can pull to bits - A zip that is the length of the circumference of a cassette - Little Phillips screw driver WHAT TO DO: 1. Unscrew the screws on the tape. 2. Pull the tape in half and take out the middle. 3. Get an oldie to help you glue gun one side of the zip around the cassette. 4. Do the same with the other side. Now you have a sweet B-boy coin purse!
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South Africa Motorhomes and Campervans is part of the Outback-Xplorer Pty. Ltd. Group. If you have any questions or require further information please do not hesitate to contact us. Our Team will be happy to answer any question you may have. No details of the vehicles displayed on the images ha ...read more
The Holiday Maker For Holiday Makers Drive through our sophisticated cities, visit our invigorating mountain resorts, laze on our spectacular beaches, or explore our vast game reserves. Tour the highways and explore the byways, travelling at your leisure, free to enjoy every aspect of the constantly ...read more
Make the most of your holiday. Never worry about struggling to pitch a tent at the end on those long hot days. Ignore timetables and deadlines. Imagine the luxury of going where you want, when you want, with your own home-from-home. Park at a waterhole and enjoy breakfast while spotting the Big 5 ...read more
Eastern Cape
Free State
KwaZulu Natal
North West
Northern Cape
Western Cape


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September 12, 2011 Another Jewish memorial vandalized in Poland http://www.jewishjournal.com/world/article/another_jewish_memorial_vandalized_in_poland_20110912 |
A Jewish memorial in eastern Poland was vandalized—the second time this month that a Jewish monument in the country was defaced. The monument to a Jewish cemetery in Bialystok that no longer exists was attacked Sunday night, local police said Monday. The bushes forming a Star of David were rearranged into a Nazi swastika on the memorial's site. Other bushes also were uprooted. It is the latest in a string of attacks on minority sites in Bialystok that includes an arson attack on a Muslim cultural center, the defacement of Lithuanian road signs and graffiti scrawled on an 18th century synagogue, Reuters reported. On Sept. 1, vandals defaced the monument in Jedwabne, Poland, that commemorates the hundreds of Jews burned alive in a barn there by their Polish neighbors in July 1941. |
JewishJournal.com is produced by TRIBE Media Corp., a non-profit media company whose mission is to inform, connect and enlighten community © Copyright 2015 Tribe Media Corp. |


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Welcome, Sign In
Kanye West's Best Quotes of 2013
Description:Kanye West is known for saying some of the most outrageously awesome quotes. John Basedow (@JohnBasedow) highlights some of Yeezus' best and most delusional verbal gems of 2013, including him telling Jimmy Kimmel he's a genius and saying to radio show 'Sway In The Morning' that he's the 'most important artist of our generation.' (1:11)
Source: Buzz60
Tags: buzz60 , celebrity news , entertainment news , john basedow


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Jamaica Bay and the Rockaways
Idlewild Park Is March's Park Of The Month
IMMEDIATETuesday, March 17, 2009
No. 20
As one of the largest remaining saltwater marshes in Queens, the 160-acre Idlewild Park gives visitors a unique window to one of the New York City's many aquatic habitats while also playing a vital role in our water system. With kayaking and canoe season beginning April 1, outdoor enthusiasts can also take to the water at the park's launch.
"Idlewild Park is one of the many natural areas we restored to re-establish the public's connection to the water." said Parks Commissioner Adrian Benepe. "Idlewild Park's kayak launch and the NYC Water Trail allow New Yorkers to explore the city from a different angle. With access to Jamaica Bay, as well as to the wetlands and surrounding areas that so many different animals call home, Idlewild Park is a great way to see and learn about the city's natural history."
The waters along the Idlewild Park Preserve, not only provide a natural backdrop to the city, but also act as a natural filtration system for Queens' groundwater, preventing any contaminants from entering Jamaica Bay. This not only improves the water quality of the area, but also helps to keep the ocean from flooding the southern half of Queens and parts of Brooklyn. Salt marshes also help reduce water erosion.
Idlewild Park is a gateway into Jamaica Bay and the water provides an astounding view of surrounding habitats, including freshwater and tidal wetlands, in addition to also the tributaries of Hook Creek. The bay is home to many different kinds of birds and marine life, including egrets, ibis, and herons, which make up 25 percent of the northeast Atlantic population.
Park of the Month introduces some of our greatest parks and green spaces to curious New Yorkers and visitors. To pick up a kayak and canoe permit or learn more about parks, visit www.nyc.gov/parks for photos of Idlewild Park and an archive of featured parks.
Directions to Jamaica Bay and the Rockaways
Know Before You Go
Seba Playground
Seba Playground will be closed to reconstruct the current Seba Tot Lot into a playground for children of all ages. The new design will enlarge the toddler area by adding a custom spray shower, seating, and two new tot play units. Additional play spaces will also be added for 5 to 12 year olds, and will include a large accessible play unit, a second spray shower and seating area. These two play areas will be joined by 15 additional swings for both age groups. The site will also feature an accessible drinking fountain, attractive plantings, and a bicycle rack.
- Barbecuing Areas
- Baseball Fields
- Basketball Courts
- Bathrooms
- Beaches
- Bicycling and Greenways
- Bocce Courts
- Cricket Fields
- Dog-friendly Areas
- Eateries
- Fitness Equipment
- Football Fields
- Golf Courses
- Handball Courts
- Hiking Trails
- Kayak/Canoe Launch Sites
- Marinas
- Model Aircraft Fields
- Nature Centers
- Paddleboat Rentals
- Playgrounds
- Roller Hockey
- Skate Parks
- Soccer Fields
- Spray Showers
- Tennis Courts
- Volleyball Courts
- Wi-Fi Hot Spots
Know when to go:
View upcoming athletic area usage in
Bayswater Park
Beach 9 Playground
Canarsie Park
Idlewild Park
Marine Park
McGuire Fields
Rockaway Beach and Boardwalk
Rockaway Beach Boardwalk
Rockaway Community Park
Spring Creek Park


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Thammasat University Business School Map (Thai)
near 2 Prachan Road, Bankok, Thailand
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Run away!
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Author Comments
This is by no means a new illustration, since I completed it around the spring of 2008! It still employs a traditionnal lineart technique I've left behind with time. This is probably my first work making considerable use of textures, and while it still has some anatomical, perspective and flow issues, I still like it somewhat! I posted it because I was revisiting some old work recently...
I certainly hope you'll still enjoy it despite its problems!
Rated 5 / 5 stars
This is again WOW :D
I love the lineart technique, I don't know why you left it behind, because this is just amazing. I don't like the glowing eye of the dragon, but that's just me, there's nothing I could criticize. An amazing piece of art :)


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Maybe we need to head out to see Ballet Arlington's performance of The Nutcracker--deemed The Nutcracker of choice by a Dallas Observer theater critic. (Odd, we thought that was Laura Miller. Or maybe Sharon Boyd.)
In any event, while various urchins from Ballet Arlington's school were lined up onstage as the "party girls" and "party boys" in Herr Stahlbaum's house for the Saturday matinee, a loud thunk came from the orchestra pit, followed by the clatter of music stands and other paraphernalia skittering across the floor. The music abruptly stopped, and the back door to the orchestra pit swung open. The dancers, who didn't know what was going on, stopped.
James Rives-Jones, conductor of the Texas Chamber Orchestra, had keeled over, and in a line Buzz thought was only used in Warner Bros. cartoons, someone called out, "Is there a doctor in the house?"
Maybe Rives-Jones was bored. We would have been. Of course, we also probably would have yelled out, "Ehh, what's up, doc?" to the woman who went hustling to the orchestra pit to help, which is one of about 1,000 reasons why Buzz should never be permitted near anything resembling high culture--not that anyone is inviting us.
Our boss, who apparently is a much classier person than one might assume if you judged her only by the company she keeps at work, was there, and says Rives-Jones, who was ill, not bored, eventually came to and was ushered out. The show continued 45 minutes later with a relief conductor, who was awarded the save.
Not really. He just got a big round of applause, though maybe the Rangers should check this guy out, since they haven't had much luck lately with actual baseball players in the bullpen.
We called Ballet Arlington to see if they could promise similar excitement at future performances, but oddly enough they didn't call back. Still, our boss' description is enough to make Buzz want to check out some dance ourselves. We're looking for something equally classy and entertaining...with a fire pole, perhaps.
You know, a real nutcracker.


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Diversity champion is convocation speaker
Peter Vogel, the founder of an organization that advances cross-cultural relations in education and other industries, is the keynote speaker at Central Wyoming College's Convocation.
Scheduled for Wednesday, August 31, Convocation begins at 4 p.m. with the traditional faculty march to the ceremony which will be held at the plaza in front of the Intertribal Education and Community Center. The ceremony, which includes the conferral of the Professor Emeritus title upon longtime math professor Carol Rardin, is open to all and is followed by a Native American dance exhibition and a picnic.
Vogel is the founder and managing director of Colorado-based CulturePrep Inc., an organization that empowers individuals and groups from around the world to overcome obstacles that threaten cross-cultural relationships.
Vogel is a noted speaker and has assisted people and groups around the world in need of better understanding and appreciation of differences. His 17 international trips in three years have led him to design Safe to Relate, CulturePrep's series of programs and services building community across cultures.
In addition to administering Safe to Relate workshops and mediation services to a variety of organizations, he has equipped more than 200 organizations with strategies to affirm diversity. He was awarded "Peacebuilder of the Year" by School Mediation Center and has been featured in television news programs and newspaper articles.
In 1999, Vogel delivered the keynote address on the topic of unity and hope for the future to 10,000 people at Uganda East Africa's largest youth rally. He has made subsequent trips to Uganda to build friendships and provide funding for small business development.
"The time is ripe for offering forums – safe places – for campuses and communities to engage in a deeper connection between diverse groups of people," Vogel was quoted as saying on a way to initiate racial discussions on college campuses.


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There are few certainties in life, but the one thing we can be absolutely sure about is that one day we will die. Not today, nor tomorrow (hopefully) but there is no escape. How it Ends is an in-depth look at possible ways in which the end will come for us mortals and the Universe as a whole. Although at first glance the subject matter may seem a little depressing, morbid even, the author, a professional astronomer at the University of Arizona, manages to bring humour as well as enlightenment to his writing. We start from the human perspective of death and how for some people the goal is to extend life by several decades; this Impey believes will be achievable in a reasonable time-frame, but whether it is desirable is another matter. However, if we are ever to reach the stars, then extending the human lifespan or at least suspending it would seem to be a necessity. Our fate as a species and the potential threats to humanity is examined in detail, including the odds of us surviving our almost reckless abuse of the planet, and avoiding any cosmic disasters which may come our way. The inevitable topic of possible life beyond Earth is discussed with a cursory glance at our immediate neighbourhood, the Solar System, followed by a wider look out among the stars for any signs that we may not be alone. We continue the journey through space and time into the far future when planets, stars and galaxies eventually cease to exist and consider the ultimate fate awaiting the Universe. Throughout the book, Impey gives credit to the many scientists whose theories, research and opinions he frequently quotes, however, he doesn't always say whether he agrees or not but leaves it to the reader to decide. I personally would have preferred him to come off the fence a little more with some of these issues. The photographs and graphics (all in black and while) could have been of better quality but that's only a minor gripe in what is otherwise a thought-provoking and entertaining read. Linda Storey |
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« Fucked Up named Album of 2011 by SPIN, on 'No Reservations' tonight, playing Brooklyn Friday, releasing Christmas single w/ Sloan & 'Year of the Tiger' single | Bear in Heaven announce tour & new album on Dead Oceans ('stream' it now) --- 2012 Tour Dates »
photos by Sarahana
The War on Drugs @ Bowery Ballroom
"War On Drugs plays with the National tonight at the Beacon Theater, but WOD had no trouble selling out a show of its own at Bowery Ballroom last night. The four-some played tracks from Slave Ambient for a sold-out crowd as part of a brief East Coast tour that ends December 17 in Philadelphia. At the Bowery stop, the band toasted the birth of a friend's first-born, passing the new dad a bottle of Maker's Mark from the stage for a sip. Father appreciation continued as frontman Adam Granduciel played a song for his dad, who was in the crowd. He thanked him for the guitar he was playing, one his dad bought for him at age 13. There was tribute too to musical forefathers as the band slipped into a cover of the Grateful Dead's "Touch Of Grey." "We've been working on this one for a while, since the early '80s," quipped Granduciel, playing it off like a fresh track." [CMJ]Though the tour ends soon in Philly, there's already another tour scheduled for 2012.
Brooklyn's own impossible-to-google TEEN opened the Bowery Ballroom show. You can get more familiar with the all-female band via a 15 minute video Sarahana shot with them below.
More pictures from the Bowery Ballroom show, also below...
Arc in Round
War on Drugs
TEEN play Secret Garden video series from hoovesontheturf (sarahana) on Vimeo.
Comments (9)
cant wait to see war on drugs again on saturday...wish arc in the round was opening
Posted by Anonymous | December 12, 2011 4:49 PM
WOW! Teen was terrible. WOD was great though...probably better than the National tonight...
Posted by seanc74 | December 12, 2011 10:56 PM
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Flywheel shaft key victory
Want to be notified when new comments are posted on this page? Click on the RSS button after you add a comment to subscribe to the comment feed, or simply check the box beside "email replies to me" while writing your comment. another skill, another $. CONGRATULATIONS!
Comment by
Tue Jun 5 21:29:17 2012
Mona --- My sentiments exactly! I was so impressed! Less time to do it himself than to load the lawnmower in the car and take it to our mechanic, even though he only lives a mile down the road.
Comment by
Wed Jun 6 07:56:38 2012
Really REALLY , tighten the nut on top of the crank shaft, The key is only there for timing purposes , the taper on the crank / flywheel is supposed to stop movement between the two as long as the nut is super tight .
Comment by
Mon Jul 28 18:01:39 2014


text:
Fri Jan 6, 2012, 09:26 PM
WillyT (62,673 posts)
Ok.. Hold Onto Your Hats... I'm Going Positive... With Much Love To DU !!!
Many moons ago, three dudes named Skinner, Elad, and EarlG, started this weird website that would eventually become... muscular. Out of a sense of hopelessness over the travesty of the 2000 Presidential Elections, they started a journey. That journey led to millions of views and posts, and is why you are looking at these pixels right now.
Now I wasn't there at the very beginning, and I would love to know what the view/post count was after the first week. But after being laid-off after 9/11, and with plenty of time on my hands, I found DU through a website recommendation article through a local newspaper about this new fangled WorldWideWeb. When I found DU, it had been going for several months by then, and I recognized it as my home. Backing up... you of tender years need to recognize that when a lot of us grew up: A.) TV was Black & White, B.) There were only 3 Channels: ABC, CBS, & NBC. And C.) THAT WAS IT! And although the argument can and should be made that those entities were far more independent, investigative, and broke/covered stories that the MSM might never cover now... a funny thing happened. At the same time that the "Inventor of the Internet" ( ) was getting screwed out of his rightful election to the presidency... the internet started bypassing the MSM. Now this took some time to occur, and some think that the Y2K "threat" might have helped to accelerate this... Windows 3.11/95/and just barely 98 being the predominate OS's at the time... But whatever happened... things have progressed. In the last 10 years or so, we now have Facebook, Twitter, I-Phones, "Social Media", et. al. We The People are bypassing the MSM on a daily basis... at high-speed. But I, here tonight, want to thank some of the pioneers of this reality... and snark at some if you must, but remember... while every pioneer wasn't necessarily sucessful, they ALL led the way. So I'd personally like to thank DU, once I found DU, for BEING DU, and for pointing me towards things/people with names like Randi Rhodes, Mike Malloy, Crooks & Liars, Digby, DailyKos, Air America, Al Franken, Rachel Maddow, Sam Seder, Cenk Uygur, Anna Kasparian, Ed Schultz, FireDogLake, ThinkProgress, Truthout, RawStory, BradBlog, TPM, and I'm gonna feel like a real shit when I post this because I sure I've left people out... NOT my intent. Point being... whether it's FDR, or Barack Obama... we WILL hold your feet to the fire, and we will plead our case, state our feelings, shed our tears, and hold each other close... even mourn the passing of those who we cannot know... if they got to see the end of the play... although I'm pretty sure NONE of get to see the end of the play... "We Are Merely Players"... But... on this first Friday of the New Year... I would like to thank ALL of the afore mentioned, those that my aging brain forgot to mention, and all of the DU family here. Like any wonderful family... we may fight some days... but it is with much love... and hope for the future of everyone. And... P.S... Huffington Post Tries... But with all of OUR eyes... DU is the best information clearinghouse on the Net. By far, So there...
41 replies, 6183 views
41 replies | Author | Time | Post |
Ok.. Hold Onto Your Hats... I'm Going Positive... With Much Love To DU !!! (Original post) |
WillyT | Jan 2012 | OP |
a kennedy | Jan 2012 | #1 | |
WillyT | Jan 2012 | #8 | |
CaliforniaPeggy | Jan 2012 | #2 | |
WillyT | Jan 2012 | #9 | |
liberalmuse | Jan 2012 | #3 | |
WillyT | Jan 2012 | #11 | |
sabrina 1 | Jan 2012 | #4 | |
WillyT | Jan 2012 | #13 | |
Surya Gayatri | Jan 2012 | #5 | |
WillyT | Jan 2012 | #14 | |
a kennedy | Jan 2012 | #6 | |
pinboy3niner | Jan 2012 | #7 | |
one_voice | Jan 2012 | #10 | |
WillyT | Jan 2012 | #17 | |
ralps | Jan 2012 | #12 | |
WillyT | Jan 2012 | #19 | |
DonCoquixote | Jan 2012 | #15 | |
Surya Gayatri | Jan 2012 | #16 | |
spanone | Jan 2012 | #18 | |
Change has come | Jan 2012 | #20 | |
T S Justly | Jan 2012 | #21 | |
ClayZ | Jan 2012 | #22 | |
Arctic Dave | Jan 2012 | #23 | |
WillyT | Jan 2012 | #28 | |
Rex | Jan 2012 | #24 | |
marions ghost | Jan 2012 | #25 | |
nadinbrzezinski | Jan 2012 | #26 | |
Scuba | Jan 2012 | #27 | |
Little Star | Jan 2012 | #29 | |
gateley | Jan 2012 | #30 | |
blondie58 | Jan 2012 | #31 | |
raouldukelives | Jan 2012 | #32 | |
Tippy | Jan 2012 | #33 | |
tpsbmam | Jan 2012 | #34 | |
cyberspirit | Jan 2012 | #35 | |
UpInArms | Jan 2012 | #36 | |
WillyT | Jan 2012 | #37 | |
Zorra | Jan 2012 | #38 | |
dixiegrrrrl | Jan 2012 | #39 | |
WillyT | Apr 2012 | #40 | |
WillyT | Apr 2012 | #41 |
Response to WillyT (Original post)
Fri Jan 6, 2012, 09:33 PM
a kennedy (9,771 posts)
1. Love you for this.......
thank you, thank you, thank you.
Response to a kennedy (Reply #1)
Fri Jan 6, 2012, 10:02 PM
WillyT (62,673 posts)
8. You Are Quite Welcome !!!
Response to WillyT (Original post)
Fri Jan 6, 2012, 09:35 PM
CaliforniaPeggy (115,136 posts)
2. My dear WillyT!
What a great essay! I could not agree more...
I wasn't here at the beginning, far from it, but DU is my home. There are so many great good people here, people I have come to know and care about! They have taught me much. As have you... Thank you! |
Response to CaliforniaPeggy (Reply #2)
Fri Jan 6, 2012, 10:15 PM
WillyT (62,673 posts)
9. My Dear Peggy...
Response to WillyT (Original post)
Fri Jan 6, 2012, 09:40 PM
liberalmuse (15,966 posts)
3. Thank you!
THIS is what DU is all about. I appreciate the reminder, and wholeheartedly agree with you. I found this site the same way you did, and finally got up the courage to join - around the same time you did.
It's been wonderful, aggravating, wonderful place to come - and no matter if I leave for months, I'm back, because there's nothing like being amongst like-minded souls, no matter how much we might disagree on some things. L |
Response to liberalmuse (Reply #3)
Fri Jan 6, 2012, 10:31 PM
WillyT (62,673 posts)
11. You Are Quite Welcome !!!
Response to WillyT (Original post)
Fri Jan 6, 2012, 09:50 PM
sabrina 1 (52,272 posts)
4. Great trip down memory lane. It's strange how so many people turned to the internet after the
stolen election. I knew nothing about political websites, I used the internet for fun mostly. It's as if there were all these people wandering in the desert trying to find a place to go to make sense of what was going on, and to find out if they were the only ones who were having these terrible feelings of foreboding.
I was not into politics much at all, but I can only say I had very, very bad feelings about Bush, and I didn't even know much of what had happened re the stolen election. I guess I got curious, no one in real life that I knew seemed to be bothered by anything, so I went online, found a political website which I thought was the only one on the internet, and ended up fighting with Bush supporters for the next two years. One day someone posted a link to what I know now was Alternet. Omg, I couldn't believe it, a place where people actually wrote coherently and didn't attack you every time you said something negative about Bush, which was everyday. There were people there from all over the world. Anyhow, I signed up and eventually became a moderator there and we had the absolutely best people including from several Muslim countries, from whom I learned nearly everything I know. I used to go back to the other board, and I don't know if they noticed, but I was a lot more informed and better able to destroy their talking points since I had a secret source of information. During the 2004 election was when I first discovered DU. I had found FR and was horrified as I used to lurk there and was terrified of them. But DUers made me realize there was nothing to fear. They were funny, witty, with great spirit and I felt so much better about our side. Mostly I lurked in the beginning, but without DU I have to say, I don't think I would have made it in a state of sanity after the election, if it had not been for DU. I miss a lot of people, including some like Elizabeth Edwards who posted here for a while. Thanks Willy |
Response to sabrina 1 (Reply #4)
Fri Jan 6, 2012, 10:38 PM
WillyT (62,673 posts)
13. Anytime sabrina 1, Anytime...
Response to WillyT (Original post)
Fri Jan 6, 2012, 09:51 PM
Surya Gayatri (7,419 posts)
5. +1,000! You said it all, WillyT...
DU is like a shelter from the storm of spin in the MSM--a place to come and find out what's really going on.
"You heard it first here..." SG |
Response to Surya Gayatri (Reply #5)
Fri Jan 6, 2012, 10:49 PM
WillyT (62,673 posts)
14. Shelter From The Storm... And The Only Thing That Has Kept My Sanity... Such As It Is...
Response to WillyT (Original post)
Fri Jan 6, 2012, 09:52 PM
a kennedy (9,771 posts)
6. So I guess you haven't been to LeftUnderground yet eh??
been there done that, not a real fan.
Response to WillyT (Original post)
Fri Jan 6, 2012, 09:58 PM
pinboy3niner (41,943 posts)
7. I hear there's also a great new unmoderated progressive site...
...something called "DU2"...
Spanking myself so you don't have to... |
Response to WillyT (Original post)
Fri Jan 6, 2012, 10:25 PM
one_voice (14,666 posts)
10. Lovely!...
thanks for posting!
Response to one_voice (Reply #10)
Fri Jan 6, 2012, 11:01 PM
WillyT (62,673 posts)
17. You Are Quite Welcome !!!
Response to WillyT (Original post)
Fri Jan 6, 2012, 10:37 PM
ralps (58,608 posts)
12. Hi WillyT, Thanks for this thread!
Response to ralps (Reply #12)
Fri Jan 6, 2012, 11:06 PM
WillyT (62,673 posts)
19. Anytime ralps... Anytime !!!
Response to WillyT (Original post)
Fri Jan 6, 2012, 10:58 PM
DonCoquixote (9,239 posts)
15. Huffpo
Is the centrist site where Mark Penn and Ariana try to pretend they are not just republicans minus the jesus juice.
Response to DonCoquixote (Reply #15)
Fri Jan 6, 2012, 11:00 PM
Surya Gayatri (7,419 posts)
16. Word! n/t
Response to WillyT (Original post)
Fri Jan 6, 2012, 11:13 PM
Change has come (2,199 posts)
20. DU Rec
and a kick! Good job reminding us all why we Love it here!
Response to WillyT (Original post)
Sat Jan 7, 2012, 01:53 AM
ClayZ (8,623 posts)
22. K and R
I love DU.
I come here every day! |
Response to WillyT (Original post)
Sat Jan 7, 2012, 02:40 AM
Arctic Dave (13,812 posts)
23. Finally, an OP worth reading and replying to.
Happy New Year to you.
Response to WillyT (Original post)
Sat Jan 7, 2012, 02:52 AM
Rex (52,611 posts)
24. Awesome post this is what I like seeing
WillyT! We don't get the junk news so many out there depend on as being fact. Another fact - some here actually help report the news and are dam good at it! I don't have to say names but DU is/was always one of their 'good friends' and still is. DU is a really great gift for people that want to learn the truth and not get fucked up mentally by the M$M/corporate/infotainment agenda.
Response to WillyT (Original post)
Sat Jan 7, 2012, 03:18 AM
nadinbrzezinski (136,068 posts)
26. Positive willyt, I like it
Response to WillyT (Original post)
Sat Jan 7, 2012, 05:36 AM
Scuba (45,013 posts)
27. Thanks to time spent on DU, I am usually the best-informed party in the conversation....
... thanks to all of YOU, because YOU ARE DU.
Response to WillyT (Original post)
Sat Jan 7, 2012, 12:21 PM
Little Star (14,881 posts)
29. I started lurking here shortly after DU went up....
I was so upset about GWB's stealing the election I wanted to vomit!
There were way too many very, very smart, politically savy members here that I found it to intimidating to join in the conversation. I was not in anyway as well learned on everything political as those first members were. I watched and learned from them for a very long time before I felt comfortable enough to join in and become a part of the community. Have to admit that some of them treated me as if "what the hell are you doing here" when I first joined, but I was finally accepted. lol I think this place actually saved my sanity back then. I was able to read others who were as pissed off as I was about that theft. I also got a education on not only the Republican Party but also the Democratic Party. I am so grateful, it is hard to express my gratitude to DU and it's members past and present. Thanks for this WillyT, LS |
Response to WillyT (Original post)
Sat Jan 7, 2012, 01:06 PM
gateley (62,118 posts)
30. Outstanding, WillyT! And you've expressed how many of us feel -- beautifully!
And I SO agree with DU being the BEST info clearing house. No matter WHAT my question, DU is where I come for the answer. When people say "Google is your friend", I say yeah, but DU is so much BETTER!
Thanks for this great post, WillyT! and various other 'attaboy' smilies. |
Response to WillyT (Original post)
Sat Jan 7, 2012, 01:43 PM
blondie58 (2,291 posts)
31. you are SO right, willy T!
U was thinking the same thing today. And DU has the smartest, kindest souls in the universe. It has helped to expand my conciousness and has helped to educate me.
Thank you. |
Response to WillyT (Original post)
Sat Jan 7, 2012, 03:17 PM
Tippy (4,610 posts)
33. K&R....Great post Willy T....thanks
Response to WillyT (Original post)
Sat Jan 7, 2012, 05:05 PM
tpsbmam (3,927 posts)
34. Always love my many WillyT recs, but this one is probably my fav!
Thanks, Willy. Yep, best info clearing house anywhere -- I always head here first then branch out for more!
Response to WillyT (Original post)
Sat Jan 7, 2012, 07:19 PM
cyberspirit (67 posts)
35. Absolutely!
Thank you.
Response to WillyT (Original post)
Sat Jan 7, 2012, 07:24 PM
UpInArms (42,781 posts)
36. all I can say is - my, what a long strange ride it has been
Response to WillyT (Original post)
Sat Jan 7, 2012, 08:40 PM
WillyT (62,673 posts)
37. Thanks Everybody !!!
Response to WillyT (Original post)
Sat Jan 7, 2012, 11:09 PM
dixiegrrrrl (40,306 posts)
39. Not only were there just 3 stations on tv
we actually had to GET UP and WALK over to the set to change the channel!!
(Oh, boy, did you ever give your age away on that one, eh?) Once I found DU, there was no changing of the online channel, believe me! People who have tv and/or listen to NPR and read newspapers say to me " did you hear about_____?" and I always can say "yep, read about it on DU this morning". One stop shopping for most news, information, laughter, and poutrage....fine by me. Great post, Willy T.... |
Response to WillyT (Original post)
Thu Apr 26, 2012, 08:37 PM
WillyT (62,673 posts)
40. Just Because


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