text:
Influential stakeholders are more likely to become advocates for businesses they see as behaving responsibly.
This is the finding from recent research by Millward Brown which explored attitudes to FMCG (fast-moving consumer goods) businesses among the media, NGOs and academics. The findings highlighted the importance of responsible and sustainable business performance and communication in building reputation and advocacy – when opinion formers share their positive views with others.
Responses from the study show that opinion formers are sensitive to claims that lack substance and look for evidence of real commitment, such as:
Awareness about actual company actions is still low, suggesting an opportunity for improved communication on sustainability among FMCG businesses and these types of stakeholders.
The study was part of Millward Brown's new approach to stakeholder research.
Top seven drivers of advocacy | Strength of relationship between behaviour and advocacy %* | |
1 | Is responsible towards society | 70 |
2 | Is honest, trustworthy and ethical | 69 |
3 | Deals fairly with their supply chain | 65 |
4 | Is responsible towards the environment | 59 |
5 | Provides high quality products & services | 52 |
6 | Treats employees well | 51 |
7 | Builds and maintains positive stakeholder relationships | 46 |


text:
Zul'Gurub Stone | |
| Suggested players: 5 |
I've been sent here by Baron Revilgaz of Booty Bay to make sure this troll menace is halted. Or that it is at least halted at the gates of Booty Bay.I want action and I want results.
I want you to get in there and kill.
I want you to get in there and find me something that will help keep these trolls out of Booty Bay.
You do that and we'll make sure you get paid.
You will receive: 9 40Gains
Upon completion of this quest you will gain:- 12,870 experience

subset: commoncrawl


text:
It is only natural: when you get a brand-new PC, especially one with broadband capabilities built in, you want to connect to the Internet and see it in action. For many, the browser and the World Wide Web are the "killer-apps" of the modern PC -- the Internet is what you have a PC for, everything else is just extra fluff.
However, connecting to the Internet with a new unprotected and unpatched PC is practically inviting the nefarious and malicious to infect your PC. According to research published by Sophos in July 2005, there is about a 50% chance that an unpatched PC will be infected with malicious software within 12 minutes of connecting to the Internet. Once infected, it is almost impossible to get a PC clean again without completely reinstalling the operating system. (I wonder if there is still a 12-minute window.)To prevent the frustration that comes with reinstalling Windows, you should take the necessary steps to update, configure, and patch your new PC. Keep in mind that no matter how new your PC is, it will most likely need patching and it will definitely need to be properly configured. Here are 10 basic things you should do before attaching the Internet to a new PC.
1. Make a starter CD-ROM
Before you disconnect your old computer, take a few minutes to burn a starter CD-ROM that contains the latest version of your favorite antivirus software. I prefer to keep this simple and inexpensive by using AVG from Grisoft, but if you like Norton or McAfee those will work just as well. (I prefer to use Microsoft Security Essentials now -- AVG's nagging became distracting.)To save time later, you should put other security applications on this disk like Spybot Search & Destroy, AdAware, etc. It would also be a good idea to include any updated drivers you might need -- drivers for your video card for example. Just like Windows, your video card drivers are likely to be a little old also. You should also put drivers on this disk for peripherals that you will be connecting to your new PC, like cameras, scanners, printers, and game interface devices. Having all these device drivers residing on a single CD-ROM means you will not have to go to the Internet to retrieve them as you set up your new PC.
2. Remove the promotional apps
After going through the initial setup process where Windows identifies devices, you may be asked to register and/or activate your copy of the Windows operating system -- hold off on that for now, you can always do that later. The first thing to do is to clean up the mess that shipped with your PC. You should remove all the promotional and trial software that you do not intend to use from your new PC. This is usually the first thing I do, because invariably one of those apps will ask if I want to activate it or register it -- a process that usually involves accessing the Internet. (Sometimes they don't ask--they just assume I want them on my pristine PC). At this point you should have no connection to the Internet at all, wireless or not.
The applications to be deleted are usually ISPs advertisements like AOL and Earthlink, an antivirus app from a competitor of your current application (something you should already have ready on your CD-ROM), trial versions of Money or Quickbooks, etc. If you are not going to use these, go to the Add/Remove Programs applet in the Control Panel and remove them completely. (I had a Toshiba notebook that had an unseemly amount of unnecessary Toshiba toolbars and an application from Best Buy that started every time the notebook booted. It all had to go.)3. Install antivirus software
Install the antivirus software that you burned onto a CD-ROM in step 1. The assumption is that any PC purchased after this document is published will have Windows XP SP2 installed, but if SP2 is not installed, you could have that update ready on your disk too. In fact, if you know how, you could have some of the more important Windows patches and updates on your disk also. This would be a good time to install anti-spyware software too. (Windows 7 will most likely be the installed OS today.)4. Turn on a software firewall
Windows XP SP2 comes with a modest but still useful software firewall. Before you start surfing the Internet you should turn it on, or you can install an alternative third-party software firewall like Zone Alarm. Any alternative firewalls should have been included on the startup CD-ROM you made in Step 1. (Windows 7 has a much better installed firewall than XP. The Windows 7 firewall should be on by default, but it never hurts to check.)5. Install printers and other peripherals
Before you connect to the Internet it is a good idea to install your other peripherals to your new PC. Performing this step means that when you do connect to the Windows update page, it will see your devices and make suggestions for new Microsoft-tested (WHQL) drivers if they are available.
6. Establish a password for the administrator account
One of the most glaring security vulnerabilities in any new Windows-based PC is that it ships with a wide open administrator access to the root directory. You never want anyone but you to have unfettered access to the admin settings on your PC. And while a password could easily be bypassed by a skilled cracker, it will deter the less determined intruder.
7. Create a new user account with a password
This is almost as equally important as password protecting your administrator account. For general day-to-day activities, you do not want to be using your admin account. Instead, you should be using a user account that is also password protected (a password that is different from the one you are using for the admin account, please). This adds another layer of protection for your new PC because a user account does not have the same all-access permissions as an admin account. In some cases, malicious software will be thwarted by this level of permissions restriction alone. (Steps 6 and 7 could be combined for Windows 7. For notebooks especially, you should always have to log in with a password. Sure it can be slightly inconvenient, but it is absolutely necessary.)8. Turn off unnecessary Windows services
Microsoft has been doing a better job of this with the release of SP2, but there are still numerous unnecessary Windows services and processes running by default on most PCs. If you'd like to see how many there are just perform the three finger salute (CTRL-ALT-Delete), click Task Manager, and then select the Processes tab. All those applications, services, processes, etc. are operating in the background on your PC. The problem is that many can actually open access to your PC to the outside world without your knowledge or active consent. That access is usually justified for what the process is supposed to be doing, it is just that many times your PC doesn't need that process at all. Web servers, network messengers, debuggers are all processes you probably don't need on your personal PC. (Check out this TechRepublic download for an in-depth examination of these services and for some suggestions for which can be deactivated.) (This is a power user tip and was very important in XP, but with Windows 7 there are less unnecessary services to worry about. You could skip this step and not be too concerned.)9. Establish a system restore point
Now that you have performed the first eight steps you should take a moment to establish a system restore point. To manually create a Restore Point, you launch the System Restore utility by clicking Start | All Programs | Accessories | System Tools |System Restore and then follow the steps in the wizard. This step will establish a fall-back point if something happens to go haywire later.
10. Install and configure a router
This last step may seem like an unnecessary added expense to some, but in this age of viruses, worms, and other nasty Internet infections, a router standing between you and the outside world coming at you at broadband speeds offers another significant layer of protection. Connecting a PC directly to the Internet means that the PC gets its own IP address, which means it can be seen by every sleazebag with malicious intent. By adding a router to your broadband setup, the router gets the visible IP address and gives your new PC an internal address. In addition, routers have hardware firewalls and other features that help block the bad guys before they get to your new PC. (This step is really a given now. I don't think anyone would connect directly to the Internet today. In 2005 it was more common than you might remember, and routers were a bit of a mystery to consumers.)Also read:
Full Bio
Mark Kaelin is a CBS Interactive Senior Editor for TechRepublic. He is the host for the Microsoft Windows and Office blog, the Google in the Enterprise blog, the Five Apps blog and the Big Data Analytics blog.


text:
Research Topics
| Jun YangSummaryAffiliation: Pennsylvania State University Country: USA Publications
| Collaborators
Detail Information
- Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathwayJun Yang
Penn State Hershey Cancer Institute, Department of Medicine, College of Medicine, Pennsylvania State University, Hershey, PA, USA
Blood 115:51-60. 2010..These results suggest that targeting of PDGF-BB, a pivotal regulator for the long-term survival of leukemic LGLs, may be an important therapeutic strategy... - Antigen activation and impaired Fas-induced death-inducing signaling complex formation in T-large-granular lymphocyte leukemiaJun Yang
Penn State Cancer Institute, Department of Medicine, College of Medicine, Penn State University, Hershey, PA 17033, USA
Blood 111:1610-6. 2008..Our results demonstrate that expanded T cells in patients with LGL leukemia display both functional and phenotypic characteristics of prior antigen activation in vivo and display reduced capacity for Fas-mediated DISC formation... - Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemiaAijun Liao
Penn State Hershey Cancer Institute, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
Blood 118:2793-800. 2011..These data demonstrate that therapeutic benefit of FTY720 may result from both altered sphingolipid metabolism as well as enhanced degradation of a key component of survival signaling... - Network model of survival signaling in large granular lymphocyte leukemiaRanran Zhang
Penn State Hershey Cancer Institute and Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
Proc Natl Acad Sci U S A 105:16308-13. 2008..The model will be useful in identifying potential therapeutic targets for T-LGL leukemia and generating long-term competent CTL necessary for tumor and cancer vaccine development... - Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemiaXin Liu
Penn State Hershey Cancer Institute, Pennsylvania State University College of Medicine, Hershey, PA, USA
Blood 116:4192-201. 2010..These data suggest that in vivo targeting of survivin through delivery of nanoliposomal C₆-ceramide may be a promising therapeutic approach for a fatal leukemia... - Developing an in vitro model of T cell type of large granular lymphocyte leukemiaTong Ren
Penn State Hershey Cancer Institute, Penn State University College of Medicine, Hershey, PA 17033, United States
Leuk Res 37:1737-43. 2013..This model should be useful for investigating molecular pathogenesis of the disease and for developing new therapeutics targeting T-LGL leukemia. .. - An association between microscopic colitis and celiac diseasePeter H R Green
Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA
Clin Gastroenterol Hepatol 7:1210-6. 2009..Microscopic colitis has been associated with celiac disease. We aimed to determine the extent and significance of this relationship... - Pirfenidone inhibits T-cell activation, proliferation, cytokine and chemokine production, and host alloresponsesGary A Visner
Department of Medicine, Children s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA, USA
Transplantation 88:330-8. 2009..In this study, we tested the hypothesis that pirfenidone has immune modulating activities and evaluated its effects on the function of T-cell subsets, which play important roles in allograft rejection... - Cutting edge: L-selectin (CD62L) expression distinguishes small resting memory CD4+ T cells that preferentially respond to recall antigenRichard L Hengel
Division of Infectious Diseases, Department of Medicine, Georgetown University School of Medicine, Washington, DC 20053, USA
J Immunol 170:28-32. 2003..These findings suggest that CD62L expression facilitates immune surveillance by programming CD4+ T cell blood and lymph node recirculation, irrespective of naive or memory CD4+ T cell phenotype... - Metanephric mesenchyme contains embryonic renal stem cellsJuan A Oliver
Department of Medicine, Columbia University, New York 10032, USA
Am J Physiol Renal Physiol 283:F799-809. 2002..The pluripotency of the 7.1.1 cells is self-renewing. The data suggest that the metanephric mesenchyme contains embryonic renal stem cells... - Innate immunity in HIV infection: enhanced susceptibility to CD95-mediated natural killer cell death and turnover induced by HIV viremiaShyam Kottilil
Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health NIH, Bethesda, MD 20892, USA
J Acquir Immune Defic Syndr 46:151-9. 2007..In addition, these NK cells, particularly the CD56(dim) CD16(bright) subset, undergo enhanced cell turnover in vivo, as demonstrated by intracellular Ki67 expression... - High-affinity binding of [3H]cimetidine to a heme-containing protein in rat brainRebecca Stadel
Center for Neuropharmacology and Neuroscience, Albany Medical College MC 136, 47 New Scotland Ave, Albany, NY 12208, USA
Drug Metab Dispos 36:614-21. 2008..Finally, CC12 is a new, potent inhibitor of CYP2B6 and CYP2C19 that may be a valuable tool for P450 research... - RanBPM, Muskelin, p48EMLP, p44CTLH, and the armadillo-repeat proteins ARMC8alpha and ARMC8beta are components of the CTLH complexNobuaki Kobayashi
Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama City 236 0004, Japan
Gene 396:236-47. 2007..Finally, we confirmed the cellular localization of these proteins. Taken together, our results reveal that RanBPM, ARMC8alpha, ARMC8beta, Muskelin, p48EMLP, and p44CTLH form complexes in cells... - A means for targeting therapeutics to peripheral nervous system neurons with axonal damageThais Federici
Neurosurgery 60:911-8; discussion 911-8. 2007..Because nerve cell bodies are important in initiating and controlling axonal regeneration, targeted delivery is an appealing strategy to deliver therapeutic proteins after peripheral nerve injury... - Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminalsJun Yang
The Berman Gund Laboratory for Study of Retinal Degenerations, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA
Hum Mol Genet 16:1017-29. 2007..We propose that Mpp4 organizes a presynaptic protein complex that includes PMCAs and has a role in modulating Ca(2+) homeostasis and synaptic transmission in rod photoreceptors... - Arginine vasopressin in periaqueductal gray, which relates to antinociception, comes from hypothalamic paraventricular nucleus in the ratJun Yang
Institute for Pharmaceuticals and Medical Science, Guangdong Bangmin Pharmaceutical Co Ltd, Jianghai Distract, Jiangmen, Guangdong 529000, China
Neurosci Lett 412:154-8. 2007..The data suggest that AVP in PAG, which relates with pain modulation, comes from PVN... - Zap70 signaling pathway mediates glucocorticoid receptor-dependent transcriptional activation: role in the regulation of annexin 1 expression in T cellsMohammad Ishaq
Laboratory of Molecular Cell Biology, SAIC Frederick, National Cancer Institute, Frederick, MD 21702, USA
J Immunol 179:3851-8. 2007..To summarize, our data demonstrate an important role for Zap70 signaling in GR-mediated transactivation in T lymphocytes and also point out a crucial role of this kinase in maintaining normal ANXA1 levels in these cells... - Hepatoma-derived growth factor binds DNA through the N-terminal PWWP domainJun Yang
Department of Pediatrics, Division of Pediatric Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA
BMC Mol Biol 8:101. 2007..In this study, we aimed to identify if HDGF is a DNA binding protein, map the functional DNA binding domain and DNA binding element for HDGF... - GLP-1 amplifies insulin signaling by up-regulation of IRbeta, IRS-1 and Glut4 in 3T3-L1 adipocytesHong Gao
Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Rui Jin 2nd Road, Shanghai, 200025, China
Endocrine 32:90-5. 2007..These results indicate that GLP-1 and its analogue exendin-4 can amplify insulin signaling in 3T3-L1 adipocytes by up-regulation of some crucial insulin signaling molecules... - Proteasome-dependent degradation of alpha-catenin is regulated by interaction with ARMc8alphaTakeyuki Suzuki
Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, 3 9 Fukuura, Kanazawa Ku, Yokohama 236 0004, Japan
Biochem J 411:581-91. 2008..Furthermore, ARMc8 knockdown inhibited alpha-catenin degradation and prolonged the half-life of alpha-catenin. We conclude that ARMc8alpha associates with alpha-catenin and up-regulates its degradation... - Genetic control of floral zygomorphy in pea (Pisum sativum L.)Zheng Wang
National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200032, China
Proc Natl Acad Sci U S A 105:10414-9. 2008..Based on the genetic analysis in pea, we suggest that variation in both the functions and interactions of these regulators could give rise to the wide spectrum of floral symmetries among legume species and other flowering plants... - Platelet glycoprotein Ibalpha forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWFTadayuki Yago
Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma 73104, USA
J Clin Invest 118:3195-207. 2008..We conclude that in type 2B vWD, prolonged lifetimes of vWF bonds with GPIbalpha on circulating platelets may allow ADAMTS-13 to deplete large vWF multimers, causing bleeding... - Regulation of Kupffer cell TNF gene expression during experimental acute pancreatitis: the role of p38-MAPK, ERK1/2, SAPK/JNK, and NF-kappaBMichel M Murr
Department of Surgery, James A Haley VA Hospital, University of South Florida, Tampa, Florida, USA
J Gastrointest Surg 7:20-5. 2003..The seemingly limited duration of NF-kappaB activation may be important in "switching off" the cytokine cascade during acute pancreatitis... - Arginine vasopressin enhances periaqueductal gray synthesis and secretion of enkephalin and endorphin in the ratJun Yang
Institute for Pharmaceuticals and Medical Science, Guangdong Bangmin Pharmaceutical Co Ltd, Jianghai Distract, Jiangmen, Guangdong 529000, China
Brain Res Bull 71:193-9. 2006..The data suggest that AVP enhances PAG synthesizing and secreting enkephalin and endorphin rather than dynorphin through V(2) receptors... - Intermedin1-53 protects the heart against isoproterenol-induced ischemic injury in ratsYue Xia Jia
Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100083, China
Eur J Pharmacol 549:117-23. 2006..These results suggest that the intermedin receptor system was up-regulated in isoproterenol-induced myocardial ischemic injury and intermedin1-53 might play a pivotal cardioprotective role in such injury... - Characterization of the common wheat (Triticum aestivum L.) mutation line producing three pistils in a floretZheng song Peng
Department of Biology, China West Normal University, Nanchong, Sichuan, PR China
Hereditas 141:15-8. 2004..According to the Recommended rules for gene symbolization in wheat, the name of the dominant gene for three pistils trait in the line TP was suggested as Pis1... - Oligomeric beta-structure of the membrane-bound HIV-1 fusion peptide formed from soluble monomersJun Yang
Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA
Biophys J 87:1951-63. 2004..However, the functional assays do suggest that small oligomers may be more fusogenic than either monomers or large aggregates... - New ouabain-conjugated peptide found from phage displayed peptide libraryMing juan Zhang
Department of Cardiology, the Second Hospital and School of Medicine, Xi an Jiao Tong University, Xi an, People s Republic of China
Am J Hypertens 17:619-23. 2004..The purpose of this study was to find ouabain-conjugated peptides (OCP) to block or to antagonize actions between endogenous ouabain (EO) and sodium pump, to serve as theoretical and experimental bases of EO in hypertension... - Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblastsKarim Fizazi
Departments of Genitourinary Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Clin Cancer Res 9:2587-97. 2003.... - TagA, a putative serine protease/ABC transporter of Dictyostelium that is required for cell fate determination at the onset of developmentJ Randall Good
Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, 77030, USA
Development 130:2953-65. 2003.... - Tamo selectively modulates nuclear import in DrosophilaSvetlana Minakhina
Waksman Institute, Department of Molecular Biology and Biochemistry, NJ Cancer Center, Rutgers University, 190 Frelinghuysen Road, Piscataway, NJ 08854 8020, USA
Genes Cells 8:299-310. 2003..An important aspect of all NF-kappaB/Rel pathways is the translocation of the Rel proteins from the cytoplasm to the nucleus, where they function as transcription factors... - Centrifugation of human lung epithelial carcinoma a549 cells up-regulates interleukin-1beta gene expressionJun Yang
Clin Diagn Lab Immunol 9:1142-3. 2002 - Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPMHaruko Ideguchi
First Department of Internal Medicine, Yokohama City University School of Medicine, 3 9 Fukuura, Yokohama 236 0004, Japan
Biochem J 367:87-95. 2002..Finally, ubiquitin conjugation to RanBPM was inhibited in a dose-dependent manner by the addition of recombinant USP11. We conclude that RanBPM was the enzymic substrate for USP11 and was deubiquitinated specifically... - Acute pancreatitis induces FasL gene expression and apoptosis in the liverScott F Gallagher
Department of Surgery, James A Haley Veterans Affairs Medical Center, University of South Florida Health Sciences Center, Tampa, Florida, USA
J Surg Res 122:201-9. 2004..We previously demonstrated that Kupffer cell-derived cytokines mediate liver injury. In this work, we sought to characterize the role of Fas Ligand (FasL) in liver injury during acute pancreatitis... - Protective effects of intermedin/adrenomedullin2 on ischemia/reperfusion injury in isolated rat heartsJing Hui Yang
Institute of Cardiovascular Research, Peking University First Hospital, Beijing 100034, China
Peptides 26:501-7. 2005..01), respectively. Interestingly, the above IMD effects were similar to those of adrenomedullin (10(-8)mol/L). These results suggest that IMD, like adrenomedullin, exerts cardio-protective effects against myocardial I/R injury... - Fas/FasL play a central role in pancreatitis-induced hepatocyte apoptosisScott F Gallagher
Departments of Surgery, James A Haley Veterans Affairs Medical Center, University of South Florida Health Sciences Center, Tampa, Florida, USA
J Gastrointest Surg 9:467-74; discussion 474-5. 2005..The manipulation of interactions between Kupffer cell-derived FasL and hepatocytes may have important therapeutic implications... - Neuronal affinity of a C7C loop peptide identified through phage displayThais Federici
Department of Neuroscience and Center for Neurological Restoration, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA
J Drug Target 14:263-71. 2006..The neuronal binding properties of this peptide may be applied in the development of neurotropic viral vectors... - Signature patterns revealed by microarray analyses of mice infected with influenza virus A and Streptococcus pneumoniaeHong Zhang
Z BioMed Inc, 15725 Crabbs Branch Way, Rockville, MD 20855, USA
Microbes Infect 8:2172-85. 2006..The advantage of this novel approach is that the detection of pathogens is based on the differences in host gene expression profiles in response to different pathogens instead of detecting pathogens directly... - Only arginine vasopressin, not oxytocin and endogenous opiate peptides, in hypothalamic paraventricular nucleus play a role in acupuncture analgesia in the ratJun Yang
Department of Nuclear Medicine, Nanfang Hospital, Guangzhou 510515, China
Brain Res Bull 68:453-8. 2006..The results suggested that only AVP, not OXT and endogenous opiate peptides in PVH involved acupuncture analgesia in the rat... - Intermedin1-53 activates L-arginine/nitric oxide synthase/nitric oxide pathway in rat aortasJing Hui Yang
Institute of Cardiovascular Research, Peking University First Hospital, Beijing 100034, China
Biochem Biophys Res Commun 341:567-72. 2006..All these results suggest that IMD1-53 might regulate vessel function homeostasis via upregulating the L-Arg/NOS/NO pathway... - Novel insights into the mechanism of action of FTY720 in a transgenic model of allograft rejection: implications for therapy of chronic rejectionAntje Habicht
Transplantation Research Center, Brigham and Women s Hospital and Children s Hospital, Boston, MA 02115, USA
J Immunol 176:36-42. 2006..These data have important implications for targeting the sphingosine 1-phosphate receptor 1 in solid organ transplantation... - Different expression patterns of duplicated PHANTASTICA-like genes in Lotus japonicus suggest their divergent functions during compound leaf developmentJiang Hong Luo
National Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Shanghai 200032, China
Cell Res 15:665-77. 2005..Our data suggest that LjPHANa and LjPHANb play important but divergent roles in regulating adaxial-abaxial polarity of compound leaves in L. japonicus... - Effect of relaxin on myocardial ischemia injury induced by isoproterenolJing Zhang
Institute of Cardiovascular Research, Peking University First Hospital, Beijing 100034, China
Peptides 26:1632-9. 2005.... - Floral patterning in Lotus japonicusZhi cheng Dong
National Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
Plant Physiol 137:1272-82. 2005..Our findings suggest that gene duplication, change in expression pattern, gain or loss of functional domains, and alteration of key gene functions all contribute to the divergence of floral patterning in L. japonicus... - Cell-cycle-dependent regulation of human aurora A transcription is mediated by periodic repression of E4TF1Masatsugu Tanaka
First Department of Internal Medicine, Yokohama City University School of Medicine, Yokohama 236 0004, Japan
J Biol Chem 277:10719-26. 2002..We conclude that the transcription of aurora A is positively regulated by E4TF1, a ubiquitously expressed ETS family protein, and that the CDE/CHR element was essential for the G(2)/M-specific transcription of aurora A...


text:
Localization study of co-phthalocyanines in cells by Raman micro(spectro)scopy
Arzhantsev, S.Y. and Chikishev, A.Y. and Koroteev, N.I. and Greve, J. and Otto, C. and Sijtsema, N.M. (1999) Localization study of co-phthalocyanines in cells by Raman micro(spectro)scopy. Journal of Raman Spectroscopy, 30 (3). pp. 205-208. ISSN 0377-0486
Restricted to UT campus only : Request a copy 247kB |
Abstract: | An investigation of intracellular localization of Co-phthalocyanines is reported. The Raman images of K562 cells stained with phthalocyanine were acquired. To understand the peculiarities of the Raman images, measurements were performed at different z-axis positions. The intracellular concentration of phthalocyanine was estimated. A colocalization study was carried out using the fluorescence probes FITC-dextran and acridine orange by means of Raman and fluorescence microscopy. Partial colocalization with both probes was revealed. |
Item Type: | Article |
Copyright: | © 1999 Wiley InterScience |
Faculty: | Science and Technology (TNW) |
Research Group: | |
Link to this item: | http://purl.utwente.nl/publications/71537 |
Official URL: | http://www3.interscience.wiley.com/journal/60500864/abstract |
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Metis ID: 128412


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Congrats, its all over the LSR board folks talking about the hot Dodge Daytona. I listened to your runs via meridix internet radio - sounded good! Wish I coulda been there. I still hold one ECTA record in Ohio, but I'm saving my car for the Texas Mile in October where I can open it up on the concrete.
Congrats again, glad the CarPC worked out.


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Thursday, April 30 2009
The Wrestler
Like 'The Ram', we do whatever we can to make it in this world with our dignity or our bodies – though rarely both – intact.
Monday, April 27 2009
Summer of Same: June 2009
This month's "original" fare offers a take on a Sid and Marty Krofft classic, more battling seizure robots, and the retaking of '70s subway thriller. Everything old is new again.
Sunday, April 26 2009
Summer of Same: May 2009
May's titles include the fourth films in two aging franchises, more Pixar perfection, and the reboot of a TV series from 40 years ago. And they say there are no new ideas.
Thursday, January 15 2009
The New Classics - The 30 Best Films of 2008
Unlike previous years, where classics came crawling out of the celluloid woodwork with regular reckless abandon, 2008 was more calm… and considered. That's not to say that choosing 30 top titles was hard. The difficulty in placing them in some manner of rank order suggests the actual depth of quality involved.
Tuesday, January 13 2009
Iconic - The Top 20 Male Performances of 2008
Like the gladiators of old, 2008 resembles a battle of formidable acting gods, especially when looking over the 20 choices presented below. Indeed, if anything, choosing a winner requires more of a leap of faith than any amount of critical skill - they all were that good.
Tough and Tender - The Top 20 Female Performances of 2008
Twenty talented ladies, 20 performances worthy of multiple little gold men. Unfortunately, as in all years, someone has to come out on top. But after looking over this impressive list, picking the preeminent turn of 2008 seems almost impossible.
Thursday, December 18 2008
Exquisite Agony
This holiday season, Mickey Rourke (in The Wrestler) and Will Smith (Seven Pounds) suffer for all us sinners.


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- Price: $145.00
- Exclusive Price: $1200.00
Celltel Phone CRE Loaded Template 21341
CRE Loaded Template 21341 is specifically a CRE Loaded 6.2 Patch 13 Template that was composed by our webmaster artist Di. It is also available as osCommerce Template 17727.
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Description, Sources, Software & Requirements
Cell Tel site template for mobile phones and cellular services.
There is a platinum dominated color scheme with white and blue accents.
There is a silver logo which says Cell Tel which you can customize.
There are various large photos of phones in the header area including a Nokia N93i.
The template has two columns with gray backgrounds and white text. Celltel Phone CRE Loaded Template 21341 has a width of 826 pixels and is available in the following sources: .PSD, and .PHP. Software required includes Winzip 9+ (Windows) or Stuffit Expander 10+ (Mac) for uncompressing .zip files, Adobe Photoshop CS+, Hosting with PHP4x and MySQL4x, Adobe Dreamweaver 8+ (or any php-editor), Apache Only (on Unix/Freebsd/Linux/Windows), and CreLoaded 6.2 patch 13 Standard, Pro Only. It has had a total of total of 2 downloads since it first appeared.


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Educate, Motivate, Advocate
GiG of ECW's mission is to provide support to persons with gluten intolerances, including celiac disease, dermatitis herpetiformis, and other gluten sensitivities, in order to live healthy lives.
Celiac Disease is one of the most common and under-diagnosed diseases today. It is estimated that 1 in every 133 people in the USA is affected by this disease. Sadly, 97% of them do not know it.
Celiac Disease is an auto-immune disease where the consumption of gluten [protein found in wheat, barley, rye] causes the body to attack [and damage] the small intestine. Untreated, this condition can lead to malnutrition since nutrients are not being absorbed properly.
Learn more about Celiac Disease... • Don't miss GiG's Educational Bulletins...
Dermatitis Herpetiformis (DH) is a chronic hereditary auto-immune skin disease the presents with groups of itchy, watery, blisters or pimples. Ingestion of gluten triggers the immune system so that it deposits Immunoglobulin A) under the top layer of skin [creating the itchy, watery blisters].
In DH, the primary target is the skin, whereas in celiac disease the damage occurs in the small intestine.
Learn more about Dermatitis Herpetiformis... • A great Continuing Medical Education article on Dermatitis Herpetiformis...
Gluten Sensitivity [also known as Non Celiac Gluten Sensitivity, The Gluten Syndrome] is a condition that is still evolving in the eyes of mainstream medicine. Only recently has the existence of Gluten Sensitivity been proven by the medical/research profession.
GS can present with many of the same symptoms of CD, however it does not present with intestinal damage. Because testing is focused on intestinal damage, the results in those with GS generally come back negative or inconclusive. This makes diagnosing GS even harder than CD. This means patients can often suffer longer because the condition is generally overlooked once celiac disease testing comes back negative.
Dr. Alessio Fasano [medical director of Univ. of Maryland's School of Medicine – Center for Celiac Research], reports seeing 60-70% of his patients fitting his criteria for gluten sensitivity. This means they test negative for CD and wheat allergy, but experience resolution of symptoms on a gluten-free diet. There's a growing number of doctors that say GS effects 10 – 30% of the population.
Learn more about Gluten Sensitivity... Also see our Gluten Sensitivity Links...


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Posted by steve9955 on 7/30/2014 2:49:00 PM (view original):what a shock.... down again. This was once a great site -- sucks now. Where is this major update that we were promised ages ago? grrrrrrrrrrrrrrrrrrrrrrrrrrrrrrr
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Seecamp Kel-Tec Rohrbaugh NAA Guardians Other Holsters Magazine Pouches Price List RJ'isms NRA America's First Freedom Ad |
Current Delivery Time is Approx 6-8 Weeks ~ See Menu to the left for some examples of my holsters ~ ~ I am sometimes asked to explain the way my holsters work ~ [see " Holster Use" link in Menu] No Excuses Guarantee, if not pleased, return for full refund, minus shipping charge. |
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Hancock (PG-13 Version/ Unrated Version/ Blu-ray/ 2-Disc) (2008)
Release Date: 25th November 2008
Director: Peter Berg Cast: Will Smith, Charlize Theron, Jason Bateman, Eddie Marsan, Johnny Galecki, Thomas Lennon
Price: $19.99
Estimated shipping is 5-10 working days.
043396279001 |
Studio: |
Sony Pictures |
Production Year: |
2008 |
Runtime (minutes): |
194 |
Region: |
Release Date: |
25th November 2008 |
Category: |
Action |
Format: |
Academy Award(R) nominee Will Smith (Best Actor, "The Pursuit Of Happyness", 2006) stars in this action-packed comedy as Hancock, a sarcastic, hard-living and misunderstood superhero who has fallen out of favor with the public. When Hancock grudgingly agrees to an extreme makeover from idealistic publicist Ray Embrey (Jason Bateman, "Juno"), his life and reputation rise from the ashes and all seems right again - until he meets a woman (2003 Academy Award(R) winner Charlize Theron, Best Actress, "Monster") with similar powers to his and the key to his secret past.Notes:
Additional Audio: Thai 5.1; "Superhumans: The Making of 'Hancock'"; "Seeing the Future"; "Building A Better Hero"; "Bumps and Bruises"; "Mere Mortals"; "Suiting Up"; "Home Life"; On-Set Visual Diary Bonus View Picture-in-Picture Track; Digital Copy of the Theatrical Version of the Film, Behind The Scenes Featurette, Featurette.Audio: 5.1 TRUEHD Video: LBX, 16:9, BLU-RAY Ratio: 2.35:1


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Dr. David A. Solomon, MD
Pulmonary Disease
- 13000 Bruce B Downs Blvd Ste 111C
Tampa, FL 33612 - 3 Locations
- (813) 972-7543
Dr. David A. Solomon graduated from the University of Maryland School of Medicine in 1969. He works in Tampa, FL and 2 other locations and specializes in Pulmonary Disease. Dr. Solomon is affiliated with H Lee Moffitt Cancer Center, James A Haley Veterans Hospital, Memorial Hospital Of Tampa, Saint Josephs Hospital and Tampa General Hospital.
Pulmonary Disease
Medical School: University of Maryland School of Medicine; Graduated 1969
*This physician has multiple office locations. See Office Information for details.


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The role of spreadsheet knowledge in user developed application success
McGill, T.J. (2005) The role of spreadsheet knowledge in user developed application success. Decision Support Systems, 39 (3). pp. 355-369.
*Subscription may be required
Spreadsheets are the most commonly used tool for end user development of applications, and organizations depend heavily upon them for decision making. This paper reports on a study to investigate the role of spreadsheet knowledge in the successful use of spreadsheet applications. It considers both the spreadsheet knowledge of the user developer and the spreadsheet knowledge of the user and tests a model of the effect of spreadsheet knowledge on the success of a user-developed spreadsheet application. Spreadsheet knowledge was shown to be important in two ways. It influences the quality of the system being developed, but it also acts directly upon the individual impact of the application. Successful use appears to require sufficient knowledge to understand and, if necessary, alter the application.
Publication Type: | Journal Article |
Murdoch Affiliation: | School of Information Technology |
Publisher: | Elsevier |
Copyright: | Copyright (c) 2004 Elsevier B.V. All rights reserved. |
URI: | http://researchrepository.murdoch.edu.au/id/eprint/825 |
Item Control Page |
Downloads per month over past year


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- Comments
Amazon has the Activision Skylanders Giants Single Character (Hot Head) for $15 with free shipping on $25+. This is regular price, but it's hard to find and doesn't stay in stock long.
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Cake - thanks for the kind thoughts. It was great having such a close battle this year - shame we can't do the same in the Championship. Maybe one day in the Premier League !
I've just entered this evening and I notice that it's up to 5057 entrants. I think the limit is 5500 according to earlier posts so it's probably worth getting in now.
Good luck with the recovery - I've had a long road back to this and I can't wait.


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98 stories found.
Photo Essay
Thailandscape Wide
Panoramic images of beautiful landscape from all over the Luscious Land of Thai's.
Personal Post
Noa Siegrist....
Hoya Infrared Filter R 72 Infrared Landscape Photography..by Todd Damiano
Nikken pimag water Nikken air filter custom lights Hadco landscape lighting Hinkley lighting...
Photo Essay
Abstraction of Morning Light
A short exploration of light,form and the landscape of skin
Photo Essay
Winter Silence
As an oasis of silence - the snow lies quiet on the landscape, mountains and forests.
Photo Essay
Arizona's Dramatic Beauty
The varied beauty and landscapes of Arizona that most people never get to see.
Feature Story
Behind the Shot: Arches National Park
A day in the life of a landscape photographer...
Photo Essay
Storefront Cemetery (Vol. II)
Welcome to the new landscape. Welcome to tomorrow. Welcome to nowhere....
Photo Essay
Storefront Cemetery (Vol. I)
Welcome to the new landscape. Welcome to tomorrow. Welcome to nowhere....
The Project
Light Project
With only a camera, a car and a little creativity, you can create striking landscapes of light.


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What is now the College of Professional and Continuing Studies opened in Fall 1946 as the La Salle Evening Division, with 36 men meeting in six courses on Monday, Tuesday, and Thursday. Shortly thereafter, the Evening Division was having "a tremendous impact on Delaware Valley industries with over 350 different businesses and industrial concerns … represented in the student body." In its first two decades, the Evening Division attracted students primarily concerned with professional and skills-oriented curricula, "in Chemistry, Electronic Physics, and Applied Mathematics." Accounting, Industrial Management, and Engineering Physics were the more popular majors, and three local companies, General Electric, Philco, and RCA, each had more than 100 employees attending La Salle at night. By the 1970s, new job opportunities in fields related to public welfare engendered a wave of student interest in the social sciences, particularly Psychology and Criminal Justice. Later, Computer Science and Business Administration attracted the largest number of students.
Many socioeconomic changes took place in the 1970s. Residents and businesses moved from the city to the suburbs. The Christian Brothers' history of "meeting students where they are" provided a supportive context for the plans to educate adults. To meet the growing demand for undergraduate and graduate studies, the Bucks County Center in Newtown Pennsylvania was established in 1997 and the Montgomery County Metroplex in Plymouth Meeting Pennsylvania was established in 2008..
La Salle University's dedication to innovation, accessibility, and outstanding academic quality within the context of the College of Professional and Continuing Studies strives constantly to maintain its reputation as one of the region's best institutions for educating adults. The College of Professional and Continuing Studies' leadership, instructors, and staff are committed to ensuring that all participants receive the very best opportunities in lifelong learning.


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Seventy years ago tomorrow, a Category 3 hurricane that forecasters failed to predict ripped through New England. It was the autumnal equinox, full harvest moon and high tide. Death and destruction reigned.
I grew up hearing about this awful, but intensely fascinating event. I have a Web page about this with links to many Web sites that have information and photographs.
Remembrance of the event was covered last night on the Boston news. This is the memorial plaque and rock on the waterfront in Watch Hill, Rhode Island.
Dedicated to gravestone research and photography, personal family history, technology and research ideas. Guided by my inner light, I strive to help others enjoy their ancestors. Charter Member of the Gravestone Rabbits.
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Saturday, September 20, 2008
1 comment:
- Colleen Johnson said...
Wow! Just found this post. I grew up in RI and often heard about this. I'm going to check out your web site.
I remember hearing my grandmother say that she was dancing on the front lawn during this because they didn't know how bad it was going to get. She lived in Providence at the time and it flooded later on. - 11:02 AM
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text: NATURE LOVE Shea Butter Body Balm 4 oz & 8.5 oz An extra rich and luxurious botanical body cream made with organic African shea butter, organic California lavender water and healing organic herbs. A rich and soothing formula that penetrates deep into the skin's layers. Synergies: Lavender & Orris Ylang Ylang Everlast Flower Rosemary & Mint Massoia Bark Clementine Sage Leaf Vanilla Litsea Patchouli Frankincense Eucalyptus Leaf Juniper Berry |


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At the moment, these are just ideas, and we can run as many or as few as we want at a time. So take a look at what's floating around and lets get some feedback!
Club Necessities
< EDIT: >Made a placeholder icon(recognize it from 'new years evil'? :3 Pen tool is my BITCH >D) for the moment, but if anyone wants to take a go at it still, feel free!< /EDIT >
With the conversion to a group, we now can use a 50x100 icon!
Should we keep the one we've got, or give the iconnists and gif-fiends out there a chance to put something together to bring the club into the new year with?
Holiday Themes
January is fast upon us, and giving time for entries to come in, that makes an excellent window to open a Valentines Day contest. We could open entries from Jan 1st all the way through Feb 13th, with the winners announced on the holiday!
Comm-Jumping Idea Contest
Over on the piper_trickster LJ community, some comm-wide interest was sparked in the ideas of Rogues + steampunk redesigns. That in itself has PLENTY of room for contest material!
Thank you Rabenstolz for the suggestion!
Questions, comments, suggestions? Toss them in below! <3


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COLUMBIA — After 23 years in operation, Cool Stuff is permanently closing its retail location and moving into a virtual home online.
Rally House, which sells sporting gear and team apparel, will soon occupy the space that currently houses Hot Box Cookies, a late-night, fresh cookie bakery at 808-B E. Broadway, and Cool Stuff, an exotic products and trinket store at 808 E. Broadway.
Arnie Fagan, who owns both the building and trinket store and co-owns the bakery, said he and Rally House "very recently" signed the lease agreement that will take effect in May.
Paraphrasing "The Godfather," Fagan said Rally House "made me an offer I couldn't refuse. So, I didn't." The sports-themed apparel business approached Fagan about its need for a space to expand its operations.
"I think it'll end up being a very good thing for them and a very good thing for me," he said. "You have to make decisions every day as to what's going to be better and worse in which situation."
Cool Stuff will need to be out of its space in April and Hot Box Cookies by mid-May.
The trinket store will continue to run its store closing sale through April and sell items from Fagan's personal collection such as a "Yin Yang pendant" that had once been requested by a customer. Fagan plans to create a website called www.coolstuffland.com where people can share stories of their experiences with the store.
"There are so many stories like that that I really want to share with the community and with the world," he said.
The website will also showcase photos from patrons and recorded music that has been played in front of the store throughout the years. Fagan said he plans to sell only a few one-of-a-kind products and unique art on the website.
Next door, Corey Rimmel opened Hot Box Cookies with two other partners in 2008. Fagan said he became its co-owner in January 2011, when it wasn't faring well economically.
Rimmel said their business partnership was dissolved sometime in the past week.
A deal is in the works for the bakery's new location in Columbia, and Rimmel said he plans to reopen sometime during summer.
"I plan on making Hot Box Cookies into an extremely successful business," he said. "There will be a lot of changes. It's still the same name and still the same recipe."
Rally House hopes to open in July after renovating the building and combining the two separate spaces into a single unit, Fagan said. "This is a historic building, and they're going to be making some really positive changes to fix it up and bring it to the next level."


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For over four decades, RMI guides have been guiding and climbing on all seven continents, searching for the greatest mountaineering adventures around. Our international programs represent our collection of favorites and there is something for everyone; from treks to high altitude climbs and week-long adventures to months-long expeditions. Come climb with us!
Carstensz Pyramid
$18300 | 23 days | Difficulty: |
The highest continental summit in Australasia, the remote and challenging Carstensz Pyramid, lies tucked deep in the heart of Papua's Sudirman Mountains. Come join us on this, the most elusive of the seven summits.
Vinson Massif
$40300 | 23 days | Difficulty: |
The highest point in Antarctica, Vinson towers above the icy interior of the continent. An expedition to its remote flanks is an unrivaled mountain adventure to a landscape rarely visited.
Kilimanjaro Climb & Safari
$5900 | 15 days | Difficulty: |
Climb to the Roof of Africa through some of the continent's most majestic landscapes and afterward witness the greatest wildlife spectacles on earth where lions and elephants still rule the plains.
Kilimanjaro Climb Only
$4900 | 12 days | Difficulty: |
Scale Kilimanjaro's jungled flanks to the mountain's icy summit in an unforgettable journey designed expressly for those seeking the adventure of Kilimanjaro but limited by the constraints of time.
North America (International)
Mexico's Volcanoes
$2700 | 9 days | Difficulty: |
The volcanoes overlooking Mexico's central valleys challenge mountaineers with high altitudes and exciting glacial climbing in an expedition to two of North America's highest mountains.
Mt. Elbrus Southside
$4900 | 13 days | Difficulty: |
In a journey to the top of Russia's forgotten corners, climb the rolling glaciers overlooking the fabled Caucasus Mountains of Europe's highest peak.
Mt. Elbrus Northside
$5100 | 17 days | Difficulty: |
The north side of Mt. Elbrus is the wild and forgotten face of Europe's highest point. This is the ideal expedition for climbers interested in building their climbing skills while getting off the beaten track on one of the Seven Summits.
Mt. Elbrus Ski Expedition
$4900 | 13 days | Difficulty: |
In a journey to the top of Russia's forgotten corners climb the rolling glaciers, overlooking the fabled Caucasus Mountains of Europe's highest peak.
Mt. Everest Southside
$66000 | 74 days | Difficulty: |
Led by Everest's most experienced guides and supported by some of the best Sherpa staff on the mountain, our Everest Expedition is the ideal approach to climbing the world's tallest mountain.
Everest Base Camp Trek
$4600 | 21 days | Difficulty: |
The unbelievable scenery and rich culture make the Everest Base Camp Trek the experience of a lifetime and the perfect way to explore the Khumbu region of Nepal.
Cho Oyu
$20700 | 44 days | Difficulty: |
The Turquoise Goddess in Tibetan, Cho Oyu is the world's sixth highest mountain. It is regarded as one of the most accessible of the world's 8,000 meter peaks and the perfect introduction to high altitude Himalayan mountaineering.
$20700 | 44 days | Difficulty: |
Shishapangma is the 14th highest mountain in the world, and the only 8,000m peak lying solely in Tibet. For a peak of this size and stature, the Northwest Ridge, our climbing route, offers a direct route to Shishapangma?s Central Summit.
South America
$4700 | 24 days | Difficulty: |
Meaning Sentinal of Stone, Aconcagua is the highest mountain in the world outside the Himalaya, towering over the rest of the Andes. It is an excellent peak for climbers to build their expedition and mountaineering skills.
Chile's Volcanoes Ski Mountaineering Expedition
$3200 | 13 days | Difficulty: |
The Chile Ski Mountaineering Expedition is a thirteen-day adventure in Northern Patagonia in Chile featuring excellent climbing and long ski descents of the region?s volcanoes.
Ecuador's Volcanoes: Cotopaxi & Cayambe
$3000 | 11 days | Difficulty: |
Climbing these glaciated peaks, whose tops soar above the Andes and bases reach into the Amazon, brings mountaineers on an exhilarating climbing expedition through Ecuador's vibrant culture to the thin air of its highest peaks.
Ecuador Volcano: Cotopaxi Express
$2700 | 9 days | Difficulty: |
As the Ecuadorian volcanoes' crown jewel, Cotopaxi challenges climbers with its impressive glaciers and lofty altitude and is the ideal mountain for climber's seeking to build their climbing skills and reach new heights.
Expedition Skills Seminar - Ecuador
$3200 | 14 days | Difficulty: |
Climb Ecuador's great high altitude volcanoes while establishing a solid foundation of mountaineering skills and techniques in order to prepare for bigger peaks in the future.
Machu Picchu
$3600 | 13 days | Difficulty: |
Journey from the streets of Cusco, along ancient winding Incan footpaths, to the legendary city of Machu Picchu perched high in the rugged Peruvian Andes.
Expedition Skills Seminar - Peru
$3800 | 16 days | Difficulty: |
Climb in the peaks of Peru's Cordillera Blanca while establishing a solid foundation of mountaineering skills and techniques in order to prepare for bigger peaks in the future.
Alpamayo Expedition
$6100 | 16 days | Difficulty: |
Alpamayo, one of the world's most beautiful mountains, is an exciting expedition that is both technically and physically demanding.


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Electrodynamic Space Thruster Innovative Propulsion System Video
Innovative Propulsion System using a Phase-shifted Array of Transverse Impulse Drives (f=c/L) http://www.crossfirefusion.com/thruster
Read the full transcript
Browse Most Popular Videos
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text: Clients spending more before stopping treatment, DVMs say Jul 01, 2003 By Daniel R. Verdon DVM360 MAGAZINE 12Next Cleveland-The economic cap on veterinary care is rising, DVMs say. Table 1: Estimate the total dollar amount at which most of your clients would refuse or stop treatment for their pets In an exclusive state of the profession survey, veterinarians were asked to estimate the total dollar amount in which most clients would refuse or stop treatment. The average for 2003 was $961 - a 21 percent increase over the 2000 average of $795. In 1997, the average stop-treatment point was $576 (Table 1). DVM Newsmagazine's survey was mailed to 1,500 U.S. practitioners. Three hundred fifty-two veterinarians responded to the survey achieving a 23 percent response rate with a ± 5 percent error (Methodology, p. 29). Table 2: Estimate the total dollar amount at which most of your clients would refuse or stop treatment for their pets In regard to the stop-treatment average, a great disparity was cited in the survey when the results were cross-tabulated by the type of species treated. In fact, the average stop-treatment point for exclusive companion animal practitioners tipped the scales at $1,087, while the average dropped significantly for predominantly small animal practitioners, $587, and mixed practitioners, $599. When these data were broken out by practice gross revenues, the stop-treatment estimate also declined significantly. In practices generating less than $250,000 in gross revenue, the average dropped to $729, whereas larger grossing practices ($750,000-plus) the average jumped 46 percent to $1,061 (Table 2). Table 3: Over the past 12 months, to what extent has cost affected your clients' decisions to treat (or continue treatment of) sick or injured animals? A disparity in answers also exists between men and women respondents. In fact, women exacted a 10 percent higher stop-treatment average than men ($927 average for men, and $1,020 average for women). This economic trend also was cited by owners, partners and associates in practice. Owners' stop-treatment average was $1,012, while partners capped treatment at an average of $815 and associates, $825. The survey shows that cost is a limiting factor for treatment for 41 percent of clients. Table 4: What percent of euthanasias are client requested or doctor suggested? The trend line from DVM Newsmagazine surveys conducted in 1997, 2000 and 2003 was consistent. The surveys asked: "Over the past 12 months, to what extent has cost affected your clients' decisions to treat (or continue treatment of) sick or injured animals?" In 2003, veterinarians believe that about 60 percent of their client base says cost did not limit treatment of sick or injured animals (Table 3). Under the category, "cases for which cost was a factor, but client agreed to recommended treatment," some interesting differences were noted by respondents. The average percentage actually increased along with gross revenue. For example, respondents estimating "cases for which cost was a factor, but client agreed to recommended treatment" include: Less than $250,000 gross: 29.7 percent $250,000-$499,000: 28.9 percent $500,000-$749,000: 34.5 percent More than $750,000: 38.5 percent Practitioners in larger grossing practices say that cost is an issue with clients, but they are still forging ahead with treatment. Larger grossing practices also report higher dollar average stop-treatment points and are more willing to accept pet insurance. Methodology Power of suggestion Euthanasia remains a client-requested service as opposed to "doctor-recommended." On average, 72.5 percent of clients request euthanasias, while 27 percent are doctor-suggested (Table 4). The average number of euthanasias conducted in a typical month dropped slightly. The average number of dogs euthanized in a month was 8.5, while the number of cats was 6.7. In DVM Newsmagazine's 2000 survey, the average number of dogs was 10.9, while cats averaged 8.3. Euthanasia numbers also increased proportionately when measured by practice gross. For example, dog euthanasia averages included: Less than $250,000 gross: 4.2 $250,000-$499,000: 5.8 $500,000-$749,000: 7.8 More than $750,000: 10.7 Client requests to euthanize healthy animals is not a rare event, and in the majority of cases it is caused by a behavior problem, veterinarians say. In extreme cases, some veterinarians report it happens every week. Only 7.6 percent of the veterinarian respondents say it never happens. Table 5: How often are you approached to euthanize healthy animals? Of the survey respondents, 5.6 percent say they are asked to euthanize healthy animals weekly, while 7.1 percent say it happens several times a month. About 9 percent say this request comes in every month, while 40 percent say owners ask to put down healthy pets several times a year. About 29 percent of the respondents say it happens yearly or less frequently. When these data are broken out by practice size, differences are noted (Table 5). Behavior problems is also the most popular reason for requests to euthanize healthy animals, veterinarians say. In fact, 79 percent of the most common reasons cited by veterinarians were behavior related. The survey asked: "What are the primary reasons behind requests to euthanize healthy animals?" The top reasons include: Behavior problems: 46 percent Aggression (i.e. biting): 22.8 percent Inappropriate urination/sanitary concerns: 9.6 percent. Owner moving: 22.2 percent Death of an owner: 7.1 percent Old age: 8.4 percent Unable to care for pet: 10 percent It's important to note that financial considerations did not rank in the top categories for respondents. An inability to afford veterinary bills was only mentioned by 6.8 percent of survey respondents. 12Next Hot topics on dvm360Vetcetera: APOP says more than half of U.S. pets are overweight Apr 03, 20154 core skills to help you deliver bad news to veterinary clients Apr 03, 2015A veterinarian's view on exercising with pets Apr 02, 2015Michigan state veterinary board rules against Dr. Pol Mar 26, 2015Photo gallery: The top 10 veterinary schools in America, according to U.S. News Mar 26, 2015|More|


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Had 3 nights in November, perfect weather, quiet Riad, 10 minutes walk to the souks, lovely staff, excellent cooking of both breakfasts and dinners. Nothing was too much. Would go back without hesitation!
- Official Description (provided by the hotel):
- An oasis of calm in Marrakech, Riad Porte Royale dates from 1750. Lovingly renovated, it has a plunge pool in the courtyard. Rugs, textiles and objets d'art from the caravan routes of Africa and Asia accent the white rooms. Sleeping 10 to 12, it is perfect for the discerning traveller, families looking for a home from home, or a group booking a special occasion. Excursions and meals can be arranged, and airport pick-up is complementary ... more less
- Also Known As:
- Riad Porte Royale Marrakech


text:
Sierra Towers
There are no available listings here today, but you can create a Condo Alert and you'll be notified as soon as one comes on the market. If you are considering selling please contact us - we have buyers waiting for inventory.
About the Building
Beata Mandell
Executive Realty Group310-765-2229
Interested in this building?
Contact Beata Today!9255 Doheny Rd, Los Angeles, CA 90069
- Year Built1965
- Floors32
- Units146
- Height395
- Neighborhood West Hollywood
- Building Type High-Rise
- Ownership Condo
Building Amenities
- 24/7 Security
- Catering Kitchen
- Concierge
- Fitness Center
- Locker Rooms
- On-site Management
- Outdoor pool
- Spa / Hot Tub
- Building Type: High-Rise
Parking Features
- Valet Parking
Based on information from California Regional Multiple Listing Service, Inc. as of April 28th, 2015 at 1:30am PDT. This information is for your personal, non-commercial use and may not be used for any purpose other than to identify prospective properties you may be interested in purchasing. Display of MLS data is usually deemed reliable but is NOT guaranteed accurate by the MLS. Buyers are responsible for verifying the accuracy of all information and should investigate the data themselves or retain appropriate professionals. Information from sources other than the Listing Agent may have been included in the MLS data. Unless otherwise specified in writing, Broker/Agent has not and will not verify any information obtained from other sources. The Broker/Agent providing the information contained herein may or may not have been the Listing and/or Selling Agent.


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After closely dodging a major public transportation strike of the LIRR (Long Island Railroad) earlier this week (which would have trickled down to affect MTA buses and subways, thereby affecting all New Yorkers and not just those who commute into the city from suburban Long Island), folks here are still breathing a sigh of relief in this city where, it seems, nearly everyone takes public transportation. Speaking of which, the Citi Bike program has expanded its service to embrace more tourists by making it more accessible for casual one-off users. Compared to typical bike rental outlets Citi Bike's $10 for a 24-hour period seems like a deal. However the drawback is that is you only get the bike for 30-minute increments before having to re-check it out - or suffer heavy fines. More info here.
Continuing in the bike loving NYC theme, this month 122 metal bicycle sculptures (see below) have been rolled out around Manhattan and Brooklyn as part of a grand scale sculpture exhibit by 83-year-old bicycle-loving Mexico City artist Gilberto Aceves Navarro. He first created the cycle themed sculpture exhibit entitled "Las Bicicletas" in his hometown with the stated goal of celebrating both art and bike riding. Supported financially by the Parks Department and the DOT (Dept. of Transportation) the public art installation can be seen all over lower Manhattan and Brooklyn, with many strategically installed near the Citi Bike share racks. More detailed info.
1984's Ghostbusters, set in New York City, is among the free films screened in NYC this week
The bevy of free outdoor movies continues with a wide range of choices of movies and locations to view them that include tonight (July 16) at Pier 63 at Hudson River Park (near 23rd Street) where the award winning 2013 film American Hustle will screen for free. This is a great location and does not get as packed as some of the other spots like Bryant Park but note that the front half of the lawn, which is damp most of the time so bring a plastic sheet, is on a backward slant from the screen so try to avoid sitting there or you will keep falling backwards. More info. Meanwhile at the aforementioned Bryant Park's (42nd Street at Sixth Ave.) weekly HBO sponsored screening this Monday (July 21s) will be National Lampoon's Vacation. More info. Over in Brooklyn at McCarren Park tonight (July 16) SummerScreen presents Ben Stiller's silly but fun Zoolander. What makes this free outdoor movie series extra special is that they also have a live concert beforehand. This evening that will be the must-see double bill of two hot new NYC hip-hop acts Ratking and Princess Nokia. 6 pm start time with film screening at sundown (8:30pm approx). McCarren Park is at N. 12th St. at Bedford Avenue, Williamsburg. More info. Then on Friday evening at Pier 46 (again on Hudson River Park) "Ghostbusters (trailer above) will screen at part of the summer movie series' Family Fridays with free popcorn to accompany the free movie. Pier 46 is along West St. at Charles St. More info.
Summer is officially well underway here in New York City with proof being that there are simply too many things going on simultaneously to possibly attend them all - a good thing because every day there is a myriad of fun events (mostly free, and mostly outdoors) to chose from ranging from music concerts of all genres, to films in fun locations, to dance productions, and art shows, etc. These include the must-attend annual summer tradition of the Tools of War grassroots hip-hop produced Park Jams which take place in parks in the Bronx and Manhattan over the three main summer months on either Tuesday or Thursday late afternoon/early evenings. Since it's now July that means that the Park Jams, with the focus on the DJs, are happening at Crotona Park up in the Boogie Down Bronx - bringing the phenomenon, that gave birth to hip-hop four decades ago, back full circle.
Last week, up until the summer thunderstorm kicked in the last quarter of the four-hour event, those entertaining included 1980's DMC champ DJ Cheese, "forever" host Grandmaster Caz, and legendary hip-hop DJ Jazzy Jay who is pictured top care of Ignacio Soltero. (Soltero also took photo above from one of last month's Spanish Harlem Tools of War Park Jams at White Park). Tomorrow (Thursday July 10) at the Crotona Park, Bronx location at the same time (4pm-8pm) the lineup will include DJ Cash Money, DJ Jazzy Joyce, and DJ Looie Loo. For full listings see flyer below or click here.
Boot Camp Clik "Trading Places" - The legendary BK crew throw a free BBQ/concert tomorrow
Yesterday (June 3rd) was the official launch of this season's annual citywide park concert series SummerStage with a free show by Ty Dolla $ign at Red Hook Park in Brooklyn. The series continues this evening at the same location where Mark McGuire, Marissa Nadler, and Delicate Steve all perform (again for free) at 7:00pm. An excellent triple bill this show is worth it just to check out Mark McGuire alone who plays an array of instruments and musical styles that include mandolin, drum machines, guitars (electric and acoustic), and a Talkbox as witnessed on the former Emeralds member's latest solo album Along the Way whose sound Amoeba.com likened to "early New Age—think Tangerine Dream and Brian Eno." More info.


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X-Men Producer and Screenwriter Spill the Beans
Kaley Cuoco Shows Off Her Tennis Skills
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The Ultimate List of Must See Summer Movies
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9 Unforgettable TV Interviews
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Film Review: In The Name Of My Daughter
Teen Titans Live Action is Headed to TNT
15 Horror Movies Only Adults Will Understand
Marvel Studios Announces New Dates and Titles
14 Movie Heroes Who Should Fight Each Other
Walking Dead's Star Goes From Good Girl to Bad on The Flash
12 Things You Didn't Know About Heath Ledger's Role In The Dark Knight
Robert Downey Jr. Confirms Iron Man 4 is on the Way!
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Fox Considers Comebacks For '24,' 'The X-Files' & 'Prison Break'
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Will The Hulk Come Back?
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Four TV anchors from local markets across the country were invited to the White House Monday to interview President Obama. His policy agenda was to talk about the federal budget. The political strategy is also familiar: leap over the national press corps and into people's living room. NPR's Mara Liasson reports.


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With the exception of Garry Tradeau's "Doonesbury," "For Better or For Worse" is the only major comic strip with aging characters. Daughter Elizabeth Patterson born in 1981, is now twenty years of age. Characters have died, characters have been born. Families have moved away while others came to fill their homes. Lifelong friends continue to share their devotion with one another, while others just drifted away with the passage of time. Some of those friends got married and had kids of their own.
The Pattersons live in a fictional southern Ontario suburb. The setting and the characters of the strip closely follow the life of its creator and author, Lynn Johnston. The mother/wife of the strip, Elly, is Lynn in many ways. John, the dad, is a dentist and resembles Lynn's husband, Rod. Son Michael, now in his mid-twenties, has finished university with a major in journalism. Elizabeth, the older daughter, is hoping for a teaching career. April, the younger daughter just now entering junior high, still provides a youthful energy to the strip, especially now that her siblings have left. And, of course, there have been the various pets through the years, dogs Farley and Edgar and Mr. B, the resident rabbit. The Pattersons have lived in the same home for the entire duration of the strip.
The strip occasionally explored outside the family. Michael's friend Gordon was frequently the target of domestic abuse from his father. One of the neighbor's wives had to go through the pain of her husband's affair. Another one of Michael's friends, Lawrence, revealed himself to be gay to the surprise of his family. Even though the subject matter was handled very delicately, the series was controversial enough to convince some United States newspapers to drop the comic strip permanently. The family itself has suffered through car accidents and dropped frozen turkeys on toes (not so funny to the victim of the plucked toes). They've also lost parents. However, they're lives are not completely full of Doom and Gloom, which makes identifying with them easy. An obvious love exists that cannot die.
While some may dismiss the day to day happens of a modern suburban family as "domestic trivialities," the fact is that millions of readers continue to make the strip one the most successful of the last twenty years. And why shouldn't it be? Most people don't live the troubled trials of the "Foxtrots," the smirky comebacks of "Sally Forth," or the bumbling hijinks of Bumstead in "Blondie." As funny as those strips can be, the lives of most North Americans resemble those of the Pattersons, no matter how "trivial" they are. It's the kind of strip that gently reminds to treasure one's family, no matter the troubles or the tribulations of the time.
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Wilson, L. and Head, J. W. and Parfitt, E. A. (1992) The Relationship Between the Height of a Volcano and the Depth to its Magma Source Zone: A Critical Reexamination. Geophysical Research Letters, 19 (13). pp. 1395-1398. ISSN 1944-8007
Full text not available from this repository.Abstract
It is commonly assumed that hydrostatic pressure balance arguments can be used to establish a relationship between the maximum height to which a volcanic edifice is able to grow and the depth at which the partial melts providing its magma supply are formed. Such a relationship has been used to infer various aspects of the thermal and stress state of the lithosphere beneath volcanic constructs on Earth, Mars, Io and Venus. We examine the assumptions behind this relationship (which are that: (1) a continuous pressure connection exists between source and summit, (2) the pressure around the magma source is the local hydrostatic pressure dictated by the depth below the geoid, and (3) the melt erupting at the summit has a net positive buoyancy), and show that many of them require geologically unreasonable conditions. We then critically assess the evidence cited in the literature for the relationship and find that there are other factors that may explain the observations. We conclude that volcano heights on the terrestrial planets cannot be related in any simple way to lithospheric thickness or depth to the magma source zone and we review the range of other factors controlling volcano height.
Item Type: | Article |
Journal or Publication Title: | Geophysical Research Letters |
Subjects: | G Geography. Anthropology. Recreation > GE Environmental Sciences |
Departments: | Faculty of Science and Technology > Lancaster Environment Centre |
ID Code: | 22880 |
Deposited By: | ep_ss_importer |
Deposited On: | 06 Jan 2009 09:00 |
Refereed?: | No |
Published?: | Published |
Last Modified: | 07 Jan 2015 13:45 |
Identification Number: | |
URI: | http://eprints.lancs.ac.uk/id/eprint/22880 |
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Moderate risk of baseball-sized hail and tornadoes in northwest Kansas, southwest Nebraska
The Storm Prediction Center in Norman has upgraded the storm threat in northwest Kansas and southwest Nebraska to moderate for Saturday.
Forecasting models are suggesting conditions in that sector will support the development of tornadoes and large hail – as big as baseballs in some cases.
Among the cities included in the moderate are Hays, Stockton, Colby, Hill City, Atwood and Norton.
Suzanne Fortin, meteorologist in charge of the National Weather Service in Wichita, said she wouldn't be surprised if the moderate zone for Saturday is eventually increased to include Russell and Rush counties in central Kansas.
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Differential interaction of Aggregatibacter (Actinobacillus) actinomycetemcomitans LsrB and RbsB proteins with autoinducer 2. | |
MedLine Citation:
PMID: 17526716 Owner: NLM Status: MEDLINE |
Our previous studies showed that the Aggregatibacter actinomycetemcomitans RbsB protein interacts with cognate and heterologous autoinducer 2 (AI-2) signals and suggested that the rbsDABCK operon encodes a transporter that may internalize AI-2 (D. James et al., Infect. Immun. 74:4021-4029, 2006.). However, A. actinomycetemcomitans also possesses genes related to the lsr operon of Salmonella enterica serovar Typhimurium which function to import AI-2. Here, we show that A. actinomycetemcomitans LsrB protein competitively inhibits the interaction of the Vibrio harveyi AI-2 receptor (LuxP) with AI-2 from either A. actinomycetemcomitans or V. harveyi. Interestingly, LsrB was a more potent inhibitor of LuxP interaction with AI-2 from V. harveyi whereas RbsB competed more effectively with LuxP for A. actinomycetemcomitans AI-2. Inactivation of lsrB in wild-type A. actinomycetemcomitans or in an isogenic RbsB-deficient strain reduced the rate by which intact bacteria depleted A. actinomycetemcomitans AI-2 from solution. Consistent with the results from the LuxP competition experiments, the LsrB-deficient strain depleted AI-2 to a lesser extent than the RbsB-deficient organism. Inactivation of both lsrB and rbsB virtually eliminated the ability of the organism to remove AI-2 from the extracellular environment. These results suggest that A. actinomycetemcomitans possesses two proteins that differentially interact with AI-2 and may function to inactivate or facilitate internalization of AI-2. |
Hanjuan Shao; Deanna James; Richard J Lamont; Donald R Demuth |
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Publication Detail:
Type: Journal Article; Research Support, N.I.H., Extramural Date: 2007-05-25 |
Journal Detail:
Title: Journal of bacteriology Volume: 189 ISSN: 0021-9193 ISO Abbreviation: J. Bacteriol. Publication Date: 2007 Aug |
Date Detail:
Created Date: 2007-07-19 Completed Date: 2007-09-10 Revised Date: 2013-06-06 |
Medline Journal Info:
Nlm Unique ID: 2985120R Medline TA: J Bacteriol Country: United States |
Other Details:
Languages: eng Pagination: 5559-65 Citation Subset: IM |
Department of Periodontics, Endodontics and Dental Hygiene, University of Louisville School of Dentistry, 501 South Preston Street, Room 209, Louisville, KY 40292, USA. |
Export Citation:
APA/MLA Format Download EndNote Download BibTex |
MeSH Terms | |
Actinobacillus actinomycetemcomitans
metabolism* Bacterial Proteins / antagonists & inhibitors, metabolism* Gene Deletion Homoserine / analogs & derivatives*, metabolism Lactones / metabolism* Periplasmic Binding Proteins / metabolism* Protein Binding Receptors, Cell Surface / metabolism* Vibrio |
Grant Support | |
Chemical | |
Reg. No./Substance:
0/Bacterial Proteins; 0/Lactones; 0/LuxP protein, Vibrio; 0/N-octanoylhomoserine lactone; 0/Periplasmic Binding Proteins; 0/Receptors, Cell Surface; 498-19-1/Homoserine |
Comments/Corrections |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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Adolescent Social Skills Training Program (ASST)
Recruitment status was Active, not recruiting
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- How to Read a Study Record
This study is a pre-test, post-test single group design with follow-up at month three. Twenty-four individuals total will participate in this study with 6 participants in each of 4 cohorts. Participants and their parents will complete pre-test measures including both paper and pencil measures and a video-recording to assess the participant's social interaction skills and fluency. These adolescents will participate in both group therapy and peer generalization sessions once a week over the course of twelve weeks. Upon completion of the intervention, participants and parents will complete paper and pencil and video post-test measures. Participants will be encouraged to participate in one follow-up session where the paper and pencil and video measures will be completed again.
Condition | Intervention |
Asperger's Disorder High-functioning Autism |
Behavioral: Multi-Media Social Skills Training Program |
Study Type: | Interventional |
Study Design: | Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment |
Official Title: | The Multi-media Social Skills Project: Validation of an Intervention for Adolescents With Autism Spectrum Disorders |
- Social Fluency [ Time Frame: 12 week, 3 month ] [ Designated as safety issue: No ]
- Loneliness Scale (Asher & Wheeler, 1985) [ Time Frame: 12 week, 3 month ] [ Designated as safety issue: No ]
- Social Responsiveness Scale (SRS; Constantino, 2002) [ Time Frame: 12 week, 3 month ] [ Designated as safety issue: No ]
- Strengths and Difficulties Questionnaire (SDQ; Goodman, 1997) [ Time Frame: 12 week, 3 month ] [ Designated as safety issue: No ]
Estimated Enrollment: | 24 |
Study Start Date: | November 2009 |
Estimated Study Completion Date: | April 2011 |
Estimated Primary Completion Date: | December 2010 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Experimental: Social Skills Training
All participants will take part in this arm of the study.
Behavioral: Multi-Media Social Skills Training Program
All individuals will participate in a twelve week social skills training program designed to enhance the social skills of adolescents with Asperger's Disorder or high-functioning autism. The intervention is comprised of both group therapy and peer generalization.
Detailed Description:
After consent , has been obtained, parents will complete the Autism Disorders Interview-Revised (ADI-R; Rutter & LeCourteur, 1995) to determine eligibility and the Checklist for Autism Spectrum Disorder (Mayes & Calhoun, 1999), the Social Responsiveness Scale (SRS; Constantino, 2002), and the Strengths and Difficulties Questionnaire (SDQ; Goodman, 1997) at the initial appointment with the study coordinator.
After assent has been obtained, adolescents will complete the Kaufman Brief Intelligence Test, Second Edition (KBIT-2; Kaufman & Kaufman, 1990) to determine eligibility and the Checklist for Autism Spectrum Disorder (Mayes & Calhoun, 1999), the Strengths and Difficulties Questionnaire (SDQ; Goodman, 1997) and the Loneliness Scale (Asher & Wheeler, 1985). Adolescents will also complete a standardized joint attention assessment.
After the completion of the eligibility and pre-test interventions there will be a wash of participants who do not meet eligibility requirements.
One week before the start of the program, participants will attend an introduction session to the program. At this time, participants will be filmed in a brief interaction with a typically developing peer that will be used as a baseline indicator of their social fluency.
Participants will attend the social skills intervention program once a week for twelve weeks. Each week there will be approximately 90 minutes of group therapy which will be conducted like a seminar class: the principal investigator will teach and review social interaction skills and nuances, participants will be encouraged to take an active role in the class.
During the twelve week intervention there will be three review/fluency building sessions: week four, week eight, and week twelve. The group therapy sessions for these review weeks will simply review the material that was covered during the prior three weeks. Participants will then practice what they have learned by having a conversation with a peer that will be taped.
Following the group therapy session each week, participants will join six typically developing peers in a 90 minute introductory photography class taught by one of the study's co-investigators. The photography class will give the participants the opportunity to practice the skills learned in group therapy with their peer group.
Participants will once again complete a battery of clinical and self-report outcome measures which will serve as the post-test measurements for the study. They will be filmed in a brief interaction with a typically developing peer which will be coded to obtain post-test social interaction skills and fluency scores. These evaluations will occur at completion of social skills program, and at three month follow-up.
Ages Eligible for Study: | 13 Years to 17 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Between 13 and 17 years of age
- A primary diagnosis of Asperger's Syndrome or high-functioning autism, as confirmed by the Autism Disorders Interview-Revised (ADIR; Rutter & LeCourteur, 1995)
- An IQ of 70 or above on the Kaufman Brief Intelligence Test, Second Edition (KBIT-2; Kaufman & Kaufman, 1990)
- Local to Central Pennsylvania region
Exclusion Criteria:
- A significant language delay
- Difficulty with aggression directed at peers
- A primary thought disorder
- A secondary disorder of anxiety or depression so severe as to prevent the individual's participation in the treatment
Please refer to this study by its ClinicalTrials.gov identifier: NCT01031823
United States, Pennsylvania | |
Penn State College of Medicine, Penn State Milton S. Hershey Medical Center | |
Hershey, Pennsylvania, United States, 17033 |
Principal Investigator: | Micheal J Murray, M.D. | Penn State College of Medicine, Penn State Milton S. Hershey Medical Center |
No publications provided
Responsible Party: | Michael J. Murray, M.D., Penn State College of Medicine, Penn State Milton S. Hershey Medical Center |
ClinicalTrials.gov Identifier: | NCT01031823 History of Changes |
Other Study ID Numbers: | 32300 |
Study First Received: | December 12, 2009 |
Last Updated: | January 25, 2011 |
Health Authority: | United States: Institutional Review Board |
Keywords provided by Penn State University:
Autism Spectrum Disorder |
Additional relevant MeSH terms:
Asperger Syndrome Child Development Disorders, Pervasive Mental Disorders Mental Disorders Diagnosed in Childhood |
ClinicalTrials.gov processed this record on April 19, 2015


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[Reviewer's Note: Six years ago, I reviewed a different DVD release of The Devil Bat for Monsterzine. Portions of this new review regarding the film itself are carried over from that 2002 review.] "Good night, Doctor." "Good...bye...Roy." Ah, who can forget those lines? They come from The Devil Bat, a dirt cheap horror film quickly made and released in 1940 starring the legendary Bela Lugosi. When I was young, my father purchased a bargain basement EP-recorded VHS copy of this oft-released film, and I can remember watching it several times, always smiling at the great actor's campy malevolence. While The Devil Bat definitely shows its age and budget, Lugosi makes the best of it and plays one of his best "mad scientist" roles [of course, weren't all scientists in 1940s films a bit mad?]. Here, his character has created large killer bats who are attracted to a peculiar scent he adds to a shaving lotion. It's all part of an elaborately ridiculous scheme to wreak vengeance on the Heath family who has made a fortune off of his work. He offers his new "scent" to members of this family to try out. Once they've generously placed some of the lotion on their necks, they bid farewell to the seemingly kind old doctor. "Good. . .bye" is what he replies in classic Lugosi fashion before unleashing his killer bats, who follow the scent and rip out the throats of their preordained victims. As a life-long fan of Bela Lugosi, I must admit that this is one of my all-time favorite Lugosi lines. His sinister "Good . . . bye" is up there with "I don't drink . . . wine" and other lines from Universal's Dracula and it's part of what really makes The Devil Bat so fun. Many horror film fans here at DVD Talk are probably familiar with The Devil Bat. It appeared on VHS through numerous different companies in the 1980s and 1990s. I don't recall the company that released the copy my family owned, but it was of distinctly poor quality, much as the majority of releases probably were. Its proliferation on DVD suggests to me that the film is likely in the public domain, and thus its presentation has frequently left much to be desired. There was one release of The Devil Bat that was collector-worthy, however. It was released under the umbrella "Bela Lugosi Presents" back in 2002. The print was in comparatively great shape, and the disc had several extras, including a commentary track with Bela Lugosi's son and an original old-time radio program starring Lugosi. Does Legend Films' 2008 release stack up to the "Bela Lugosi Presents" release from 2002? In terms of video and audio quality, they look and sound fairly comparable. Otherwise, not really. I confess that I am not a fan of colorization. I've always preferred watching classic films in their original black and white, so to me, Legend's new color version of The Devil Bat holds zero interest. I will talk more about this in the Video section of the review, however. Thankfully, Legend includes a black and white version. Otherwise, the only other thing that Legend's release has over the "Bela Lugosi Presents" release is its availability, as the latter is now out-of-print. Collectors, though, may be able to find it used from online sellers, and that's the route I would encourage. The extras are near non-existent on this new release, but it's definitely the second best version I've seen of this Lugosi Poverty Row "classic." Recommended. The DVD
Video: As mentioned above, Legend Films offers two versions of The Devil Bat: the original black and white, and a colorized effort. Both are in a full frame 1.33:1 aspect ratio. The black and white version is certainly an improvement over most other public domain editions of this movie. Details are much sharper. There's a slight shimmering to the image, though, and speckling, dirt, and other imperfections are noticeable. A random sampling of the colorized version suggests it's about what one expects from such an endeavor. Colors don't look quite real, with unnatural hues of brown and blue dominating the palette. It appears competently done, though, and about in line with previous colorized films I've experienced.
Both versions of The Devil Bat sport a Dolby Digital 2.0 Mono audio track. The sound is limited and tinny, but strong. Hiss and scratchiness are evident but do not impede the dialogue and music. Given the dubious quality of previous public domain releases of The Devil Bat, I found that the audio here was serviceable and acceptable, but far from exemplary.
No subtitle options appear available.
The only extra on this disc is a Legend Films Trailers gallery sporting ads for the colorized versions of Plan 9 From Outer Space, Night of the Living Dead, Reefer Madness, House on Haunted Hill, Carnival of Souls, and Little Shop of Horrors. Yawn.
Despite my antipathy toward colorization, I think it would have been nice to have a featurette on the colorization process utilized here. It's something that would be interesting to learn about.
Final Thoughts:
The Devil Bat is one of my favorite horror films from the early 1940s. Bela Lugosi is terrific in this pure camp fantasy involving a series of murders committed via large screeching bats. Legend's release of this movie ranks among the best on DVD in terms of video quality (and, if you absolutely must see a black and white film colorized, then this is the one to get). However, this new Legend release still doesn't beat the extras-heavy "Bela Lugosi Presents" DVD version released in 2002, and though out of print, that's the one I would still recommend the most to Lugosi fans.
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Women who have made great contributions to our history will be portrayed at the next Brown Bag Luncheon on noon Friday, March 8 at the North Platte Public Library.
Vicki McCarty will share stories, using costumes, pictures, dolls and antiques from her vast collection.
Women featured will include Amelia Earhart, Eleanor Roosevelt and Rosie the Riveter, to name a few.
McCarty has presented programs at the library, schools, nursing homes, and other places. She amassed her collection of costumes from relatives and has continued the hobby, studying historical periods and clothing styles through the years.
She developed her storytelling style as the activity director of a local nursing home. Her programs always evoke memories.
This program is free to the public but seating is limited. Phone the library at 535-8036 to reserve seats by March 7. Attendees may bring their lunches. Coffee, tea and water will be provided.
Flatrock Publishing, Inc. 1300 E 4th St., Suite F North Platte, NE 69101


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Infographic authored by Treks In The Wild.
To view the original post, see the original How to Identify Poison Ivy.
Discovering New Plants, Ideas and Uses Everyday
Every month there are things to do in the garden and November is no different. However, the garden is not just veggies but flowers, lawns and greenhouse.
As the season changes the - garden - is a wonderful place to hang out with lots to do! Find out what to do at: November Gardening To Do List: Flowers, Veggies Lawn and More
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