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Life Extension Magazine July 2011
Cover Story
Shed Pounds by Inhibiting Cellular Fat Storage
By Kirk Stokel
By Kirk Stokel
Health authorities are warning about the devastating consequences of obesity, yet doctors remain in the dark about what causes people to accumulate so many fat pounds as they age. Through a series of well-designed studies, scientists investigating certain plant extracts found they can block fat storage at the cellular level. In a significant scientific advance, a potent new weapon has been identified to help safely induce weight loss. This article describes how a novel dual plant extract favorably modulates six pathways that fat cells use to trigger weight gain. When tested on humans in a placebo-controlled study, those taking this dual plant extract lost 4.05 inches of abdominal fat and dropped 11.4 pounds after eight weeks…with weight loss observed as early as 14 days.1 Cells that store fat are called adipocytes. They are deposited throughout our bodies.2,3 As we age, adipocytes tend to expand and congregate in areas that are cosmetically unsightly and detrimental to our health. Of greatest concern are the adipocytes that deposit deep in our abdomens. This "visceral fat" represents more than fat stored on our waistlines. Visceral fat is chemically active tissue that churns out a torrent of pro-inflammatory cytokines.4 Those with bulging belly fat suffer constant bombardment from toxic cytokines that trigger the metabolic syndrome and its deadly consequences.5,6 This widespread problem led scientists to seek out plant extracts that specifically interfere with adipocyte fat storage in our abdominal anatomy.
How Unwanted Fat Storage OccursExcess calories transform to fat deposits in adipocytes7 through a multi-step process known as adipogenesis. When fewer calories are consumed, fat is released from adipocytes to meet the body's energy needs.8,9 This is known as lipolysis. A dual plant extract has been studied based on its ability to simultaneously inhibit adipogenesis (fat storage) and enhance lipolysis (fat breakdown and release).
Like any other cell, adipocytes develop from undifferentiated stem cells. Premature, developing fat cells are called pre-adipocytes. When you ingest more calories than your body needs, "young" pre-adipocytes respond by maturing into "adult" adipocytes.7,10-12 "Adult" adipocytes take up excess fatty acids from your bloodstream and begin expanding. It is this process of fatty acid uptake and adipocyte expansion that ultimately results in obesity and its pathologic consequences. Every excess calorie contributes to the maturation and growth of fat cells in this way. Past a certain point, adipocytes distend and become bloated, much in the same way your belly does. Not all adipocytes are the same. While fat cells distribute throughout your body, those that store in your abdomen—producing so-called visceral fat or belly fat—are more than just storage "containers." Belly fat cells are chemically active. They form fatty tissue capable of releasing detrimental pro-inflammatory cytokines.4 In obese individuals, the mass of excess visceral fat deposits generates a pro-inflammatory flood of cytokines. This cytokine release then incites a cascade of harmful effects that, if left unchecked, contributes to the onset of multiple degenerative diseases.5,6 So unwanted body fat storage happens when pre-adipocyte stem cells mature in order to store excess dietary fat (adipogenesis) while the ability to break down stored fat (lipolysis) diminishes.
Combating Surplus Body Fat StorageSearching for natural interventions that would effectively inhibit fat accumulation (adipogenesis) and enhance fat burning (lipolysis), scientists evaluated more than a thousand plants for evidence that would meet this criteria.13 Two plants whose extracts demonstrated significant biological effects were:
In the laboratory, S. indicus and mangosteen extracts powerfully impeded adipogenesis. When cells were treated with S. indicus alone, fat storage was inhibited by as much as 65%, compared with control cells. Photographs (below) show a markedly visible difference between the two cell groups. The control cells show a bloated, "foamy" appearance, bulging with fat droplets, compared to the smaller, more naturally contoured cells treated with the S. indicus extract.13 Each of these extracts also enhanced lipolysis (or fat burning), by as much as 56% compared to control cells.13 Having identified these unifying properties in the two extracts, the researchers set out to determine if they would exhibit enhanced effects when used in combination. They found that the S. indicus and mangosteen extracts favorably modulate the activity of six genomic pathways involved in fat cell formation and breakdown.13 Remarkably, these extracts reduced gene expression that promotes adipogenesis while favorably influencing a gene involved in desirable lipolysis. The box on this page shows how these plant extracts, used alone and in combination, positively modulated the markers involved in unwanted cellular fat accumulation by inhibiting adipogenesis and promoting lipolysis. Given these observations, researchers recognized that this novel blend of plant extracts could result in significant weight loss via three distinct mechanisms:
The next step was to determine if these plant extracts would induce weight loss in experimental animals and—more importantly—obese humans. Preventing Obesity in RodentsWhen young adult rats are fed a high-fat diet they rapidly gain weight—just as humans often do. To investigate the effects of the plant extracts that worked in cell studies, scientists fed a group of young adult rats a high-fat diet. Half the rats received the dual plant extract while the other half served as the control group.13 At the end of eight weeks, the control group rapidly gained weight. The rats fed a high-fat diet and given the dual plant extract, on the other hand, reduced body weight gain by an impressive 700%.13 This is not surprising considering these same plant extracts blocked fat accumulation by 48.5% and 65.9% in the cellular model.13 This study demonstrated that these plant extracts decrease diet-induced obesity in young adult rats. The real challenge, however, is whether these same plant extracts are effective in humans who are already obese.
Weight Loss Findings in HumansHuman weight loss studies comprise an active arm that received the potentially effective fat-reducing agent and a similar group that received an inactive placebo. To evaluate the effects of these two plant extracts, 60 obese adults were recruited and divided into two groups. One arm of 30 patients functioned as the placebo group while a second group of 30 patients received 800 mg per day of a combination of the two plant extracts. Both groups followed a 2,000-calorie- per-day diet and were asked to walk 30 minutes five days a week. At the end of eight weeks, the group receiving the two plant extracts showed the following improvements:1
This was a randomized, double-blind, placebo-controlled study, the kind the FDA mandates before it approves new drugs. The charts on this page reveal the magnitude of the weight loss and belly fat reduction that occurred in the group receiving the dual plant extract compared to placebo.1 (See Charts 1 and 2) In addition to the favorable results seen at eight weeks, researchers were impressed with the reduction in waist and hip circumference, as well as lost body weight that occurred within the first 14 days! In fact after only two weeks, the average weight reduction was 4.6 pounds.1 At eight weeks, the dual plant extract group showed reduction in the waist-to-hip ratio that was 2.2 times greater than the placebo group. This is an important improvement as it indicates dangerous visceral belly fat is being lost. These findings are supported by a second, similarly designed trial involving 60 obese subjects. They were divided into three groups that consisted of a placebo arm, an active arm receiving one plant extract, and another active arm that received a dual plant extract. All participants followed a 2,000-calorie-per-day diet and were asked to walk for 30 minutes five times a week for 8 weeks.13 After eight weeks the group receiving the dual plant extract experienced statistically significant changes in their abdominal circumference, total body weight, and hip circumference similar to those seen in the first study mentioned above.13 These confirmatory findings indicate that this novel dual plant extract may enable aging humans to safely shed unwanted body fat stores. No major adverse events or side effects were reported in either study. Protection against Coronary ThrombosisMost sudden death heart attacks occur when a blood clot forms in a coronary artery, choking off oxygenated blood to a portion of the heart muscle. A protein called plasminogen activator inhibitor-1 (PAI-1) inhibits the normal breakdown of arterial blood clots.29 High levels of PAI-1 are observed in obese individuals and are associated with increased heart attack risk.30,31 When studying the dual plant extract, researchers measured serum levels of plasminogen activator inhibitor-1 (PAI-1). Those receiving the dual plant extract showed a 24.3% reduction in dangerous PAI-1 levels, while the placebo group showed a 2.4% increase.1 (See Chart 3) Those supplemented with the dual plant extract had a 60% drop in triglyceride levels compared to baseline.1
Subjects given the dual plant extract increased levels of the key metabolic hormone adiponectin.1 Adiponectin regulates how much sugar is in your bloodstream and how quickly your body breaks down fat. In terms of fat loss, high adiponectin levels are desirable. Higher levels of adiponectin are associated with decreased deposits of body fat and a reduced susceptibility to diabetes and metabolic syndrome.42 The dual plant extract group showed trends toward reduced glucose and cholesterol, which are expected to occur in response to loss of belly fat and body weight.1 The loss of visceral fat in the dual extract group— 4.05 inches, amounting to twice the decline observed in the placebo group—is compelling.1 This is important because visceral fat releases a storm of pro-inflammatory cell-signaling molecules. Excess visceral fat is a known risk factor for a number of serious health threats, ranging from systemic inflammation to increased risk of hypertension, atherosclerosis, type 2 diabetes, and coronary artery disease.43-45 Taken together, these findings indicate markedly reduced vascular disease risk in obese individuals taking 800 mg a day of this dual plant extract. SummaryObesity arises from the increased size of individual adipocytes (fat cells) due to enhanced lipid (fat) accumulation. It worsens as greater numbers of pre-adipocytes transform into dysfunctional, bloated adipocytes. The novel blend of plant extracts described in this article favorably influences six distinct pathways by which fat cells trigger weight gain. In cell culture, these plant extracts reduce the ability of progenitor fat cells (pre-adipocytes) to transform into bloated fat cells. These studies also show that components of this dual plant extract reduce the amount of fatty acids taken up by adipocytes (adipogenesis) and facilitate the breakdown (lipolysis) of fat stored in existing adipocytes. In a placebo-controlled clinical trial involving obese humans, this blend of S. indicus and mangosteen plant extracts safely induced weight loss of 11.4 pounds, along with a decline of 2.05 in body mass index (BMI) and a reduction of 4.05 inches in harmful visceral fat.1 While our medical establishment has failed to offer any safe, long-term, practical solutions for today's obesity epidemic, natural agents are now available that substantively augment the effects of a sensible weight loss program. If you have any questions on the scientific content of this article, please call a Life Extension® Health Advisor at
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1. Lau FC, Golakoti T, Krishnaraju AV, Sengupta K, Bagchi D. Efficacy and tolerability of Merastin™- A randomized, double-blind, placebo-controlled study. FASEB J. April 2011; 25:(Meeting Abstract Supplement) 601.9. Presented at Experimental Biology 2011, Washington, DC. April 10, 2011. Program No. 601.9, Poster No. A278. 2. Bunnell BA, Estes BT, Guilak F, Gimble JM. Differentiation of adipose stem cells. Methods Mol Biol. 2008;456:155-71. 3. Symonds ME, Budge H, Perkins AC, Lomax MA. Adipose tissue development - Impact of the early life environment. Prog Biophys Mol Biol. 2010 Dec 14. 4. Takakura Y, Yoshida T. Beta 3-adrenergic receptor agonists--past, present and future. Nippon Yakurigaku Zasshi. 2001 Nov;118(5):315-20. 5. Xiao L, Zhang J, Li H, Liu J, He L, Zhai Y. Inhibition of adipocyte differentiation and adipogenesis by the traditional Chinese herb Sibiraea angustata. Exp Biol Med (Maywood). 2010 Dec;235(12):1442-9. 6. Bumrungpert A, Kalpravidh RW, Chuang CC, et al. Xanthones from mangosteen inhibit inflammation in human macrophages and in human adipocytes exposed to macrophage-conditioned media. J Nutr. 2010 Apr;140 (4):842-7. 7. Amini Z, Boyd B, Doucet J, Ribnicky DM, Stephens JM. St. John's Wort inhibits adipocyte differentiation and induces insulin resistance in adipocytes. Biochem Biophys Res Commun. 2009 Oct 9;388(1):146-9. 8. Frayn KN, Fielding BA, Karpe F. Adipose tissue fatty acid metabolism and cardiovascular disease. Curr Opin Lipidol. 2005 Aug;16(4):409-15. 9. Wang S, Soni KG, Semache M, et al. Lipolysis and the integrated physiology of lipid energy metabolism. Mol Genet Metab. 2008 Nov;95(3):117-26. 10. Lee J, Jung E, Huh S, Kim YS, Kim YW, Park D. Anti-adipogenesis by 6-thioinosine is mediated by downregulation of PPAR gamma through JNK-dependent upregulation of iNOS. Cell Mol Life Sci. 2010 Feb;67(3):467-81. 11. Smas CM, Sul HS. Molecular mechanisms of adipocyte differentiation and inhibitory action of pref-1. Crit Rev Eukaryot Gene Expr. 1997;7(4):281-98. 12. Fan B, Ikuyama S, Gu JQ, et al. Oleic acid-induced ADRP expression requires both AP-1 and PPAR response elements, and is reduced by Pycnogenol through mRNA degradation in NMuLi liver cells. Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E112-23. 13. Results based on initial analyses of unpublished research data. 14. Imamura M, Inoguchi T, Ikuyama S, et al. ADRP stimulates lipid accumulation and lipid droplet formation in murine fibroblasts. Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E775-83. 15. Grasselli E, Voci A, Canesi L, et al. Direct effects of iodothyronines on excess fat storage in rat hepatocytes. J Hepatol. 2010 Nov 3. 16. Imai Y, Varela GM, Jackson MB, Graham MJ, Crooke RM, Ahima RS. Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide. Gastroenterology. 2007 May;132(5):1947-54. 17. Agardh HE, Folkersen L, Ekstrand J, et al. Expression of fatty acid-binding protein 4/aP2 is correlated with plaque instability in carotid atherosclerosis. J Intern Med. 2011 Feb;269(2):200-10. 18. Aragones G, Ferre R, Lazaro I, et al. Fatty acid-binding protein 4 is associated with endothelial dysfunction in patients with type 2 diabetes. Atherosclerosis. 2010 Nov;213(1):329-31. 19. Cabre A, Lazaro I, Cofan M, et al. FABP4 plasma levels are increased in familial combined hyperlipidemia. J Lipid Res. 2010 May;51(5):1173-8. 20. Cabre A, Lazaro I, Girona J, et al. Plasma fatty acid binding protein 4 is associated with atherogenic dyslipidemia in diabetes. J Lipid Res. 2008 Aug;49(8):1746-51. 21. Chmurzynska A. The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. J Appl Genet. 2006;47(1):39-48. 22. Karakas SE, Almario RU, Kim K. Serum fatty acid binding protein 4, free fatty acids, and metabolic risk markers. Metabolism. 2009 Jul;58(7):1002-7. 23. Kersten S. Mechanisms of nutritional and hormonal regulation of lipogenesis. EMBO Rep. 2001 Apr;2(4):282-6. 24. Toruner F, Altinova AE, Akturk M, et al. The relationship between adipocyte fatty acid binding protein-4, retinol binding protein-4 levels and early diabetic nephropathy in patients with type 2 diabetes. Diabetes Res Clin Pract. 2010 Dec 19. 25. Tsai JP, Liou HH, Liu HM, Lee CJ, Lee RP, Hsu BG. Fasting serum fatty acid-binding protein 4 level positively correlates with metabolic syndrome in hemodialysis patients. Arch Med Res. 2010 Oct;41(7):536-40. 26. Li Y, Kang Z, Li S, Kong T, Liu X, Sun C. Ursolic acid stimulates lipolysis in primary-cultured rat adipocytes. Mol Nutr Food Res. 2010 Nov;54(11):1609-17. 27. Nerurkar PV, Lee YK, Nerurkar VR. Momordica charantia (bitter melon) inhibits primary human adipocyte differentiation by modulating adipogenic genes. BMC Complement Altern Med. 2010;10:34. 28. Tinahones FJ, Garrido-Sanchez L, Miranda M, et al. Obesity and insulin resistance-related changes in the expression of lipogenic and lipolytic genes in morbidly obese subjects. Obes Surg. 2010 Nov;20(11):1559-67. 29. Mutch NJ, Thomas L, Moore NR, Lisiak KM, Booth NA. TAFIa, PAI-1 and alpha-antiplasmin: complementary roles in regulating lysis of thrombi and plasma clots. J Thromb Haemost. 2007 Apr;5(4):812-7. 30. Trayhurn P, Wood IS. Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem Soc Trans. 2005 Nov;33(Pt 5):1078-81. 31. Gnacinska M, Malgorzewicz S, Guzek M, Lysiak-Szydłowska W, Sworczak K. Adipose tissue activity in relation to overweight or obesity. Endokrynol Pol. 2010 Mar-Apr;61(2):160-8. 32. Cock TA, Houten SM, Auwerx J. Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm. EMBO Rep. 2004 Feb;5(2):142-7. 33. Jiang HZ, Quan XF, Tian WX, et al. Fatty acid synthase inhibitors of phenolic constituents isolated from Garcinia mangostana. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6045-7. 34. Choi JH, Banks AS, Estall JL, et al. Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Nature. 2010 Jul 22;466(7305):451-6. 35. Oben JE, Ngondi JL, Blum K. Inhibition of Irvingia gabonensis seed extract (OB131) on adipogenesis as mediated via down regulation of the PPARgamma and leptin genes and up-regulation of the adiponectin gene. Lipids Health Dis. 2008;7:44. 36. Tsukahara T, Hanazawa S, Murakami-Murofushi K. Cyclic phosphatidic acid influences the expression and regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 cells. Biochem Biophys Res Commun. 2011 Jan 7;404(1):109-14. 37. An S, Han JI, Kim MJ, et al. Ethanolic extracts of Brassica campestris spp. rapa roots prevent high-fat diet-induced obesity via beta(3)-adrenergic regulation of white adipocyte lipolytic activity. J Med Food. 2010 Apr;13(2):406-14. 38. Hatakeyama Y, Sakata Y, Takakura S, Manda T, Mutoh S. Acute and chronic effects of FR-149175, a beta 3-adrenergic receptor agonist, on energy expenditure in Zucker fatty rats. Am J Physiol Regul Integr Comp Physiol. 2004 Aug;287(2):R336-41. 39. Lima JJ, Feng H, Duckworth L, et al. Association analyses of adrenergic receptor polymorphisms with obesity and metabolic alterations. Metabolism. 2007 Jun;56(6):757-65. 40. Sakura H, Togashi M, Iwamoto Y. Beta 3-adrenergic receptor agonists as anti-obese and anti-diabetic drugs. Nippon Rinsho. 2002 Jan;60(1):123-9. 41. van Baak MA, Hul GB, Toubro S, et al. Acute effect of L-796568, a novel beta 3-adrenergic receptor agonist, on energy expenditure in obese men. Clin Pharmacol Ther. 2002 Apr;71(4):272-9. 42. Ukkola O, Santaniemi M. Adiponectin: a link between excess adiposity and associated comorbidities? J Mol Med. 2002 Nov;80(11):696-702. 43. Koh H, Hayashi T, Sato KK, et al. Visceral adiposity, not abdominal subcutaneous fat area, is associated with high blood pressure in Japanese men: the Ohtori study. Hypertens Res. 2011 Jan 13. 44. Lee YH, Lee SH, Jung ES, et al. Visceral adiposity and the severity of coronary artery disease in middle-aged subjects with normal waist circumference and its relation with lipocalin-2 and MCP-1. Atherosclerosis. 2010 Dec;213(2):592-7. 45. Navarro E, Mijac V, Ryder HF. Ultrasonography measurement of intrabdominal visceral fat in obese men. Association with alterations in serum lipids and insulinemia. Arch Latinoam Nutr. 2010 Jun;60(2):160-7. 46. Galani VJ, Patel BG, Rana DG. Sphaeranthus indicus Linn.: A phytopharmacological review. Int J Ayurveda Res. 2010 Oct;1(4):247-53. 47. Prabhu KS, Lobo R, Shirwaikar A. Antidiabetic properties of the alcoholic extract of Sphaeranthus indicus in streptozotocin-nicotinamide diabetic rats. J Pharm Pharmacol. 2008 Jul;60(7):909-16. 48. Ramachandran S, Asokkumar K, Uma Maheswari M, et al. Investigation of Antidiabetic, Antihyperlipidemic, and In Vivo Antioxidant Properties of Sphaeranthus indicus Linn. in Type 1 Diabetic Rats: An Identification of Possible Biomarkers. Evid Based Complement Alternat Med. 2011;2011. 49. Ghaisas M, Zope V, Takawale A, Navghare V, Tanwar M, Deshpande A. Preventive effect of Sphaeranthus indicus during progression of glucocorticoid-induced insulin resistance in mice. Pharm Biol. 2010 Dec;48(12):1371-5. 50. Shirwaikar A, Prabhu KS, Punitha IS. In vitro antioxidant studies of Sphaeranthus indicus (Linn). Indian J Exp Biol. 2006 Dec;44(12):993-6. 51. Loo AE, Huang D. Assay-guided fractionation study of alpha-amylase inhibitors from Garcinia mangostana pericarp. J Agric Food Chem. 2007 Nov 28;55(24):9805-10. 52. Bumrungpert A, Kalpravidh RW, Chitchumroonchokchai C, et al. Xanthones from mangosteen prevent lipopolysaccharide-mediated inflammation and insulin resistance in primary cultures of human adipocytes. J Nutr. 2009 Jun;139(6):1185-91. 53. Udani JK, Singh BB, Barrett ML, Singh VJ. Evaluation of Mangosteen juice blend on biomarkers of inflammation in obese subjects: a pilot, dose finding study. Nutr J. 2009;8:48. |


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Scientists have found that topically applied sulforaphane has the ability to help protect the skin against the visible signs of sun related stress on the skin! Sulforaphane promotes the production of certain enzymes—such as glutathione S-transferase—that help support the skin's natural ability to fortify itself against the visible effects caused by UV radiation.114,115 Broccoli contains glucoraphanin,116 which is enzymatically converted into sulforaphane. Three-day-old broccoli sprouts are packed with up to 100 times more glucoraphanin by weight than mature broccoli plants!117 The extracts from glucoraphanin-rich broccoli sprouts which are found in Cosmesis Broccoli Sprout Cream offer maximum support against the visible effects of UV rays! In addition to glucoraphanin, several potent antioxidants are included such as aspalathin from rooibos tea and epigallocatechin-3-gallate from green tea to help reduce visible effects of UV radiation and oxidative stress.118-120 Most of the visible effects of skin aging are caused by radiation from the sun. Applied directly to the skin, the unique and synergistic combination of extracts in the concentrated Broccoli Sprout Cream provides maximum, targeted support against the visible effects of sun-related stress on the skin. |
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Purified Water, Cetearyl Alcohol, Cyclopentasiloxane, Dimethicone, Isopropoyl Myristate, Squalane, Hyaluronic Acid, Brassica oleracea Italica (Broccoli) Extract (Sprout), Helianthus annuus (Sunflower) Seed Oil, Polysorbate 60, Phenoxyethanol, Ethylhexylglycerin, Concentrated Tea Blend Extract. |
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Don't fall to pieces on Halloween -create or complete your mummy, monster, or zombie costume with this crazy pair of nude Stitches hosiery and put together an awesome costume.
- The nude Stitches hosiery are made of nylon
- Hand wash, line dry
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Super cute, but kinda big
By Scarrie from Austin, TX on 11/9/2012
Authentic Looking, Unique
Irregular Fit, Package Doesnt State Size, Very loose
Best Uses:
Just For Fun, Roller Derby, Wear To School/Work
Describe Yourself:
Was this a gift?:
Bottom Line:
Yes, I would recommend this to a friend
Comments about Stitches Nude Hosiery:
Toes need to be more tightly sown. Very loose, excess fabric around the feet and ankles.
Stating the sizing on package would be very helpful. Fits very loosely compared to other "one size fits most" tights on website.
Once on, these tights look awesome though! The stitches have a really cool affect!
Was this review helpful to you? Yes / No- Is this review inappropriate?.
This tights will have you in stiches
Comfortable, Lots of Fun, Not Gory, Stiches Look Great, Unique
Best Uses:
Costume Party, Just For Fun, Trick Or Treating, Wear To School/Work
Describe Yourself:
Adventurous, Love to dress up
Was this a gift?:
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Yes, I would recommend this to a friend
Comments about Stitches Nude Hosiery:
should have bought two. want to wear them all the time
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- All deliveries are pending approval and merchandise availability.
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Asus K93 Series
Processor: Intel Core i7 2630QM, Intel Core i7 2670QMGraphics Adapter: NVIDIA GeForce GT 540M, NVIDIA GeForce GT 630M
Display: 18.4 inch
Weight: 3.9kg, 4.1kg
Price: 1000, 1149 euro
Average of 2 scores (from 3 reviews)
mobility: 61%, workmanship: 68%, ergonomy: 75%, emissions: 88%
Asus K93SV-YZ094V
Notebook: Asus K93SV-YZ094VProcessor: Intel Core i7 2630QM
Graphics Adapter: NVIDIA GeForce GT 540M
Display: 18.4 inch, 16:9, 1920x1080 pixels
Weight: 3.9kg
Price: 1000 euro
Links: Asus homepage Asus notebook section
Source: Notebookreview.com
Das Asus K93S hinterlässt einen seltsam zwiespältigen Eindruck. Kann man es mögen, dieses zyklopische Gerät? Nicht, wenn man unterwegs mit ihm ist. Selbst ein paar Minuten mit dem Vier-Kilo-Trumm auf dem Schoß, und man verliert die Lust. Der Mitreisende am Vierertisch im ICE bedankt sich herzlich für diese überaus großzügige Blickschranke und Begrenzung seiner Ablagemöglichkeiten.
Single Review, online available, Long, Date: 08/30/2011
Rating: performance: 70% features: 50% display: 30% mobility: 40% workmanship: 50% ergonomy: 50%
Source: HardwareLuxx DE→EN
Positive: cpu, HD-resolution, Blu-ray drive, big keayboard with Num-Pad, HDMI, USB 3.0; negative: dark glare-display, gpu not sufficient for demanding games, not suited for mobile use, battery hardly accessible
Single Review, online available, Very Long, Date: 11/26/2011
Asus K93SM-YZ085V
Notebook: Asus K93SM-YZ085VProcessor: Intel Core i7 2670QM
Graphics Adapter: NVIDIA GeForce GT 630M 1024 MB
Display: 18.4 inch, 16:9, 1920x1080 pixels
Weight: 4.1kg
Price: 1149 euro
Links: Asus homepage Asus notebook section
Average Score:
Average of 1 scores (from 1 reviews)
Big item. When looking at the voluminous package of the Asus K93SM-YZ085V, the first thing that springs to mind won't be a notebook. More likely than not, you might expect an HD receiver or a Blu-ray player. Nevertheless, the box contains a notebook with an 18.4 inch display - surely not a device for everyone.
Source: Notebookinfo DE→EN
Single Review, online available, Medium, Date: 03/26/2012
Rating: Total score: 85% performance: 95% display: 70% mobility: 75% ergonomy: 90% emissions: 90%
Asus: ASUSTeK Computer Incorporated, a Taiwanese multinational company, produces motherboards, graphics cards, optical drives, PDAs, computer monitors, notebook computers, servers, networking products, mobile phones, computer cases, computer components, and computer cooling systems. The company's 2007 revenues reached US$6.9 billion. ASUS also produces components for other manufacturers. The Eee PC initiated the netbook boom in 2008.
Modern games should be playable with these graphics cards at low settings and resolutions. Casual gamers may be happy with these cards.
NVIDIA GeForce GT 540M:
Mid-range graphics card based on the GT 435M chip (GF108) with higher clock rates and DDR3 support.
NVIDIA GeForce GT 630M:
Multiple models based on various chips of the Fermi generation. Specifically, the GT 630M exists in GF108/GF106/GF116 variants, but are all essentially renamed GeForce GT 540M or 555M GPUs. A 28nm GF117 variant exists as well with reduced power consumption.
» Further information can be found in our Comparison of Mobile Graphics Cards and the corresponding Benchmark List.
Intel Core i7: The Intel Core i7 for laptops is based on the LG1156 Core i5/i7 CPU for desktops. The base clock speed of the CPUs is relatively low, but because of a huge Turbo mode, the cores can dynamically overclock to up to 3.2 GHz (920XM). Therefore, the CPU can be as fast as high clocked dual-core CPUs (using single threaded applications) but still offer the advantage of 4 cores. Because of the large TDP of 45 W / 55 W, the CPU is only intended for large laptops.
2630QM: Fast Quad-core processor based on the Sandy Bridge architecture with an integrated graphics card and dual-channel DDR3 memory controller.
2670QM: Fast Quad-core processor clocked at 2.2-3.1 GHz based on the Sandy Bridge architecture with an integrated graphics card and dual-channel DDR3 memory controller.
18.4: 18 inch display size is a rare and very big size for desktop-replacement laptops. Laptops with 18 inch displays did not exist before 2008. The DTR-laptops can't be carried easily, need much energy but on the other side texts can be read easily and high resolutions are no problem. DTR mainly are intended for stationary usage on desks, where the weight and the energy need are unimportant.
» To find out how fine a display is, see our DPI List.
3.9 kg:
This laptop is heavy below average, compared with the average of notebooks. Therefore especially desktop replacements fit in this class of weight.
4.1 kg:
81.5%: This rating should be considered to be average. This is because the proportion of notebooks which have a higher rating is approximately equal to the proportion which have a lower rating.
» Further information can be found in our Notebook Purchase Guide.


text:
Page 2 of 2 Previous
"I would urge my colleagues to stop hyperventilating," said Waxman. "The problems with HealthCare.gov are unfortunate and we should investigate them, but they will be fixed. And then every American will have, finally have, access to affordable health insurance."
The website HealthCare.gov was intended to be the online gateway to coverage for millions of uninsured Americans, as well those who already purchase their policies individually. Many people in the latter group will have to get new insurance next year, because their policies do not meet the standards of the new law.
Throughout the 3 ½-hour hearing, Sebelius was respectful, often addressing lawmakers as "sir" or "congresswoman." She kept her cool as some lawmakers repeatedly cut off her answers. But she did not shy a few times from tersely interjecting her views while a member was speaking.
The standing-room-only hearing room was silent when she swore an oath to tell the truth and began her opening statement.
Addressing consumers who've tangled with the confusing system, Sebelius added, "So let me say directly to these Americans, you deserve better. I apologize."
She parried questions about problems with the website as well as a wave of cancellation notices hitting individuals and small businesses who buy their own insurance. Those notices are coming because many existing individual policies are too skimpy to meet the law's requirements. The administration says consumers affected will be able to find better coverage.
Lawmakers also wanted to know how many people have enrolled in plans through the health insurance marketplaces. Sebelius stuck with the administration response, promising to release the data in mid-November.
Starting Jan. 1, most Americans will be required to carry health insurance or face fines. At the same time, insurance companies will no longer be able to turn away people in poor health. The law provides subsidized private insurance for middle-class people who don't get health care on the job. Low-income people can access an expanded version of Medicaid in states that agree to expand that safety net program.
Congressional Republicans have introduced competing versions of legislation to let insurance companies continue selling coverage that has been available, freeing them from a requirement to cancel policies that do not meet the standards established in the law.
One bill in the House, authored by Rep. Fred Upton of Michigan, would cover the sale of policies providing individual coverage through 2014.
Republican officials said the House was likely to vote on the issue next month.
Sens. Ron Johnson of Wisconsin and Marco Rubio of Florida back Senate legislation that would apply to existing individual or group policies, and would permit their sale indefinitely. It was not clear if or when a vote might be held in the Democratic-controlled Senate.
Identical legislation has been introduced in the House by Rep. Ron DeSantis, R-Fla..


text:
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Kata AP-321 Auxiliary Pouch fits a full size D/SLR body with battery grip attached while keeping it protected and easy to access at all times. Part of the auxiliary pouch system, the Kata AP-321 Camera Pouch can easily be attached to the auxiliary belt with the two secure locking loops on the rear. This Kata Camera Case can also be carried on any belt, attached to other Kata bags or used with the provided shoulder strap. Two mesh side pockets as well as one internal mesh pocket hold additional accessories such as filters and lens caps. An external zippered pocket will store flat accessories you need close at hand. The removable padded insert protects your gear when in place and can be removed to make the pouch flat.
We offer complete line of Kata Camera Cases, Camera Bags. For our complete selection of products by Kata on sale please visit our Kata page. For more Camera Cases, Camera Bags please visit our Camera Cases, Camera Bags store section.


text:
Swiftly out from
the friendly lilt of the band,
Waiting a sign. In
the deep heart of me
crowd's good laughter, the loved eyes of men,
I am
drawn nightward; I must turn again
Where, down beyond
the low untrodden strand,
There curves and
glimmers outward to the unknown
old unquiet ocean. All the shade
Is rife with magic
and movement. I stray alone
on the edge of silence, half afraid,
The sullen waters
swell towards the moon,
And all my tides
set seaward.
From inland
Leaps a gay
fragment of some mocking tune,
That tinkles and
laughs and fades along the sand
And dies between
the seawall and the sea.
Back to Rupert Brooke poems: 1905-1908...
Page last updated: 15 August 1998 ©1998-1999, Richard J. Yanco |


text:
In our humble opinion, nothing on Earth is too delicious to be dipped in a tub of chocolate. The folks at Fatty Sunday's must agree, because their series of gourmet pretzels all share this mouthwatering trait. With so many flavors to choose from, and so many mouthfuls to savor, the epic battle between sweet and savory may carry on forever. The winner, however, will always be you.
I have tried EVERY flavor of these delicious little treats! You can't go wrong with any of them. I ordered them for my co-workers and they were a HUGE hit! They are packaged well, just the right size, and reasonably priced for a specialty item. I would definitely buy them again!


text:
GARY, TEXAS. Gary is on Farm Road 10 ten miles south of Carthage in southwest Panola County. About 1844 or 1845 the first families began to move into the area. J. H. Thomas arrived first and built a home that was a longtime landmark. A farming community developed and produced mainly cotton. The business area, originally known as Zuber, had a post office, a cotton gin, and stores. Gary was settled when the Marshall, Timpson and Sabine Pass Railroad was built between Timpson and Carthage. In 1898 the railroad reached the Thomas J. Hull farm midway between the two towns, and Hull and S. Smith Garrison collaborated in establishing a twenty-acre townsite. A depot opened, and the settlement was named in honor of Garrison's grandson, Gary Sanford. The community soon grew to a population of 300. The post office was moved from Mount Bethel and renamed Gary in 1899. By the early 1900s Gary had developed into a bustling sawmill town, as East Texas virgin forests were being cleared. The town was the center of business for both farming and sawmill interests. It had a cotton gin, sawmills, a hotel, stores, and saloons. The Red Front Saloon was the center of social activities of the rougher sort until the county became dry in 1905. Until the 1940s cotton remained a staple crop, and the community was also a major grower of tomatoes, introduced by an agricultural pioneer and civic leader, Dr. Zack L. Daniel. Gary shared in the East Texas prosperity from the development of the oil and gas industry from the 1940s into the 1980s. The population in the 1940s was between 400 and 500. It began to decline in that decade, when the cotton industry faded in East Texas. In 1988 Gary had a population of 351. The business community around the square had a general store, the post office, a pulpwood yard, and the Gary Gas Company. The school enrolled 240 students in grades kindergarten through twelve. Local economic activity was mainly pulpwood hauling and cattle ranching. Most residents were employed outside the community. Walter Prescott Webb and Woodward Maurice (Tex) Ritterqv were born in Gary. In 1990 the population was 271, and in 2000 it was 303.
Gary School Round-Up Committee, Through the Years: A Brief History of the Gary Public School and Community (Gary, Texas, n.d.). History of Panola County (Carthage, Texas: Carthage Circulating Book Club, 1935?). Leila B. LaGrone, ed., History of Panola County (Carthage, Texas: Panola County Historical Commission, 1979).
The following, adapted from the Chicago Manual of Style, 15th edition, is the preferred citation for this article.
Lincoln H. King, "GARY, TX," Handbook of Texas Online (http://www.tshaonline.org/handbook/online/articles/hlg09), accessed April 26, 2015. Uploaded on June 15, 2010. Published by the Texas State Historical Association.


text: Pug Puppy Dudley by A Place To Love Dogs. Posted on June 8, 2013 Prev Next 08 Jun Pug puppy Cute Pug puppy Dudley modelling his new doggie harness. He thinks it looks a lot like a sweater vest and he just loves it! What do you guys think, do you like it too? @dudleydoodledandy aplacetolovedogs on instagram by A Place To Love Dogs


text:
Watch as Gary Klein demonstrates how to walk the dog.
Don't take a lot of time on the boat ramp. See how to prepare your boat for the water.
Bryon Velvick shows how he catches late fall schooling fish.
Bryon Velvick gives you the key elements to fishing a boat dock.
On days you can't get to the lake, take some time to care for your fishing gear.
What is the difference between a spinner and a baitcasting reel? Byron Velvick shows you in this clip.


text:
2 cups almond paste
4 egg whites
1 cup white sugar
1 cup slivered almonds
In mixer, place almond paste and blend in sugar. Once blended, slowly add egg white and mix until incorporated. Scoop mixture and top with slivered almonds. Bake onto ungreased cookie sheet at 325 degree for approximately 10-15 minutes. Let cool and remove from cookie sheet and place on decorative platter.
Almond macaroons
Published On: Dec 12 2012 12:55:38 PM EST
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GA Lottery Baseball Sow Live @ STATS w/ Chipper Jones updated 08.21.13


text:
MATLAB and Simulink resources for Arduino, LEGO, and Raspberry Pi
Learn moreOpportunities for recent engineering grads.
Apply TodayNew to MATLAB?
I want to create a 3D matrix by multiplying all the elements in a 2d matrix by all the elements in a vector to give a 3d matrix.
I initially used this: x=3; y=3; z=4;
flat = [1,2,3;4,5,6;7,8,9]; deep = [1,2,3,4]'; field=zeros(3,3,4);
tic for i=1:x for j=1:y field(i,j,:)=flat(i,j)*deep; end end toc Elapsed time is 0.000027 seconds.
but thought I could speed it up if I replaced the loop with:
tic for i=1:z field(:,:,i) = flat(:,:)*deep(i); end toc
Elapsed time is 0.000202 seconds. However, the first method with more loop iterations proved faster. Can anyone explain why and more importantly is there a better, more effieint method than either of these?
For larger data, you'll probably find this version the most efficient
field = bsxfun(@times, flat, reshape(deep,1,1,[]) );
However, the first method with more loop iterations proved faster.
First, the data is way too small for this to be a good test of anything. However, I think the main reason the 2nd version is slower is because you are indexing flat(:,:) unnecessarily. When I modify to
field(:,:,i) = flat*deep(i);
the 2nd version becomes faster for me.


text:
ACC can't lose with exciting FSU-Clemson showdown
OCT 15, 2013 6:06p ET
Coach Jimbo Fisher has done his best to sell the it's-just-another-game line. Players were well-coached and did a nice job of practicing the art of omerta when asked about the matchup between the fifth-ranked Seminoles and No. 3 Tigers.
Everyone tried, but there is no denying what will be one of the most significant games in Atlantic Coast Conference history. It's only the fourth time ACC teams ranked in the top 5 have played.
The showdown has become must-see television. Even Fisher finally acknowledged the magnitude of game.
"It's very important in the national title hunt, it's very important in the Atlantic Division, in the ACC, all those things," Fisher said. "That's why you come to Florida State, to be in those games, to be in those positions.
"You've got to manage it but you've got to embrace it at the same time. You've got to understand the implications of the game, but it's not a one game season, but it's a very, very important game for what we want to do and our goals and what we want to reach. ... We understand that part of it, too. But keep it in perspective and let it be what it is and enjoy the moment. Don't worry about the moment, enjoy it."
This game has drawn the kind of national interest the conference hasn't had in a while. The league has been heavily criticized for its quality of play recently, but this game has dominated headlines.
No matter who wins, the ACC can't lose.
The winner will stay in the title discussion with top-ranked Alabama of the Southeastern Conference, the Big Ten's Ohio State and Oregon out of the Pac 12.
The ACC will let Heisman Trophy hopeful quarterbacks Tajh Boyd and Jameis Winston showcase its product.
"You definitely hear it, but you definitely have to tune it out as well," Florida State tackle Cameron Ewing said. "Everybody doesn't get these types of opportunities. When we get these types of opportunities, you have to seize them.
"I play football because I love it. When you love to do something, all the preparation, all the tough days, it's all worth it. When next Saturday comes and we're getting ready to play, everybody's going to be amped up, everybody's going to be ready to play."
The stakes are huge. The scenario is not "just another game" when your season-long goals can disappear on a single Saturday.
"Huge challenge this week, obviously," Clemson coach Dabo Swinney said. "This is a great football team we're getting ready to play, possibly the best team in the country. (Our) guys, they don't hope to win. They expect to win."
Boyd added, "Of course, this game does mean more because it puts you in the driver's seat and puts you in a position where you can do the things you want to do."
Boyd is the reigning ACC offensive player of the year while Winston is Florida State's dynamic freshman. Both are either No. 1 or No. 2 in the conference in total offense, total offensive touchdowns, yards passing per game, pass efficiency, completion percentage and touchdown passes.
The Seminoles have the No. 3 scoring defense in the country while the Tigers are No. 10. Florida State is the No. 3 scoring offense and Clemson is tied for No. 17.
And the Seminoles are well aware the program hasn't won in Death Valley since 2001 -- even if they claim that's inconsequential.
"We're trying to stay calm and treat it like any other game. It's hard to do," Florida State linebacker Telvin Smith said. "Obviously we're here for a reason. These are the games that we live for. This game and Florida, those two games that you come to Florida State and say I can't wait to play in and show my talent and show what I can do
"There's so many great players on the field at the same time, who's going to stand out? Who's going to step up? Big time players show up in big time games."
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text:
Released: May 01st, 1986
Running Time: 80
Director: Gregory Dark
Company: VCA Pictures
Greg Rome, Marc Wallace, Shanna McCullough, Steve Powers, Penny Morgan, Dick Rambone, Erica Boyer, Keli Richards, Tom Byron, Jennifer Noxt, Jack Baker
Critical Rating: AAA
Genre: Feature
There is no better woman at performing anal sex than Keli Richards; except for maybe Erica Boyer. But we can't leave out Jennifer Noxt… or Shanna McCullough, either. Now that I think about it, White Bun Busters, starring all four of these wild women, has the best this sub-genre can offer. Now the anal sex and d.p. fans are taken care of.
But for everyone, White Bun Busters is as kinky as the Dark Brothers gets. And that means hot. Keli is marvelous with Tom Byron and Greg Rome at the same time; as is Byron and Shanna McCullough in a very steamy segment. Penny Morgan, probably jealous that Keli Richards withstood the enormous Dick Rambone anally in Caught From Behind IV, decides to do the same and she excels with this mammoth jock. Jennifer Noxt and Erica Boyer are no less swarmy in individual segments.
Marc Wallace and Steve Powers, starring as the A-Busters (called in to persuade sacred damsels into performing anally), generate lots of laughs as the anal-ists. Tom Byron (employed here by Acme Proctological) turns in one of the better performances of his career as a nerd trying to get his wife to take it from the back. Good dialogue, a great deal of silly (and ultimately tiresome) humor, smooth direction by Gregory Dark and decent video qualities make White Bun Busters a hot edition to a hardcore library.
(Note: The opening theme song sounds a lot like Frank Zappa and someone does a funny Don Pardo impersonation on the radio playing in Byron's office.)


text:
M-F 6am-8pm, S 7am-4pm PTReg. Price:$299.99
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text:
Albany HotelsIthaca HotelsJamaica HotelsLake George HotelsLake Placid HotelsLatham HotelsNew York HotelsNiagara Falls HotelsRochester HotelsSyracuse Hotels More hotels in USA >>
Marriott Rochester Airport 1890 West Ridge Road Rochester United States 14615
Hotel Marriott Rochester Airport Rochester Description Enjoy the comforts of our luxury guestrooms, each equipped with in-room coffee makers, and two dual line phones with voice mail, data ports, and complimentary high speed web access access.
Instantly check rates and availability online for the Marriott Rochester Airport in Rochester. Please enter your check-in and check-out dates. Kasbah.com can make hotel reservations up to one year in advance, with our simple and secure online booking procedure.
Hotel Marriott Rochester Airport Policies Guarantee Policy You must use a credit card to book on-line. Cancel Policy Cancellation policies vary from hotel to hotel. Most current and accurate cancellation policies will appear on your confirmed reservation notification. Checkin Policy 3:00 PM Checkout Policy 12:00 PM
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text:
COLUMBIA — Gerald Dean Fitzgerald, known as Dean, died Tuesday, Nov. 26, 2013, at home after a battle with cancer. He was 85.
He was born Oct. 5, 1928, in northwest Missouri and grew up in Bethany, Mo. He was the oldest of five children, born to Jesse Logan and Nellie Grace (Davis) Fitzgerald.
He was married to Helen Henderson from 1948 to 1972, and they had two daughters, Linda and Pamala, and a son, Bryan Jay, who died in 1981. Mr. Fitzgerald married Diane Berg in 1984.
He received his bachelor's degree from Northwest Missouri State University and his master's and doctoral degrees from MU.
He started his career as a dairy farmer, then became a one-room country school teacher and an elementary school principal in Chillicothe. He was the first principal of Russell Boulevard Elementary School in Columbia. In 1966, he joined the MU Extension personnel department and retired in 1993.
Mr. Fitzgerald loved flying, world travel, scuba diving and Christmas trees. He and Diane built and ran Log Providence Pines, a Christmas tree farm, for many years. He served Meals on Wheels, flew blood deliveries for the Red Cross and drove the Sunday bus for his church.
He received a lifetime award from the Missouri Christmas Tree Association, and was a founder and member of Little Dixie Kiwanis Club in Columbia, receiving the Legion of Honor award for 55 years of service. He will be remembered for loving his family, teaching and being a hard worker.
He is survived by his wife; two brothers, Harold and Edward; two daughters, Pam and Linda; three blended family children, Mike (Laura), David (Rhonda), and Kristina; nine grandchildren, Wendy, Joe, Jennifer, Kellie, Tia, Rachael, Connor, Tyler and Lauren; and four great-grandchildren, Elora, Chloe, Tristan and Caiden.
A celebration of his life will be held at 1 p.m. Monday at Missouri United Methodist Church, 204 S. Ninth St., with a light lunch to follow. In lieu of flowers, memorials are suggested to the Bryan Jay Fitzgerald scholarship fund, MU Department of Music, or a charity of the donor's choice.
Arrangements under the direction of Memorial Funeral Home.
Online tributes may be left at www.memorialfuneralhomeandcemetery.com.


text:
"Each of you should use whatever gift you have received to serve others, as faithful stewards of God's grace in its various forms." 1 Peter 4:10
The Career Development Office assists WLC students as they pursue a fulfilling and appropriate use of their natural talents. Whether students explore internships, a full-time professional career, or part-time employment opportunities, we are committed to bridging the gap between college and career and playing an active role in students' career development process.
WLC Career ConnectWe've made it easy for employers and WLC students to communicate directly to each other about employment opportunities.
Employers are invited to upload employment openings to WLC Career Connect while students are encouraged to conduct their career search via Career Connect.
Thad Jahns Career Development Director email@example.com
Sara Wierer Internship Program Manager email@example.com


text:
Street Address:
830 N. Main St.
Suite B
Viroqua, WI 54665-1646
Mailing Address:
830 N Main St Ste B
Viroqua, WI 54665-1177
Across from the Vernon County Fairgrounds
Phone: (608) 637-2999
Fax: (608) 637-6211
Toll Free: (800) 552-1087
Office Hours:
Mon-Fri 8:30am to 5:00pm
Other Hours by Appointment
My background and achievements
- Graduate-Western Illinois University
- Member-Viroqua Area Rotary Club
- Member-Viroqua Partners
- Member-Kickapoo Woods Cooperative
- Volunteer/Supporter-Habitat for Humanity
- Volunteer/Supporter-Vernon County Humane Society
- Volunteer/Supporter-Viroqua Fine Arts Association
- Volunteer/Supporter-Wild West Days
- Volunteer/Supporter-Viroqua Bluegrass & Gospel Festival
Meet the team
- Kirsten Halverson - Office Representative
- Diane Parr - Office Representative
- Tiffany Lentz - Office Representative
Our mission is to help people manage the risks of everyday life, recover from the unexpected and realize their dreams.
Driving Directions
Email Me
Do you have a policy or an account with State Farm?
Please contact this agent for a quote.


text:
Follow the Softmod ANY Wii guide, then the Update All Your IOS's guide. They are both in my signature. After that you will be able to play all new games.
Make sure you use the UpdatePack.zip in Softmod ANY Wii. That will allow you to access the Shopping Channel again.


text:
College of Law
Florida Supreme Court Briefs and Opinions
Docket #68306 - Joe Edward Lee, Petitioner, vs. State of Florida, Respondent. 501 So. 2d 591; January 29, 1987.
Initial Brief of Petitioner on the Merits
Respondents' Brief on the Merits
Petitioner's Reply Brief
Brief of Amicus Curiae
Oral Argument Video
(.wmv, 91 MB)
Florida State College of Law Library


text:
Harding, Luke (2011) Accent and listening assessment:A validation study of the use of speakers with L2 accents on an academic English listening test. Language Testing and Evaluation . Peter Lang, Frankfurt. ISBN 978-3-631-60939-2
Full text not available from this repository.Abstract
Given the linguistically diverse nature of academic institutions in English-speaking contexts, a strong rationale exists for the incorporation of L2 accents of English in academic listening assessment on the grounds of authenticity and construct representation. However large-scale tests have tended to feature only native-speaker varieties in listening test input owing to concerns about the intelligibility of L2 accents, construct validity and acceptability. This book presents a mixed-methods study designed to address these concerns. Versions of the University Test of English as a Second Language (UTESL) featuring Australian English, Japanese and Mandarin Chinese accented speakers were used to explore the potential for a shared-L1 or familiarity advantage, and to investigate test-takers' attitudes towards L2 accents on a listening test. Implications are drawn for test development and for future research.
Item Type: | Book/Report/Proceedings |
Subjects: | P Language and Literature > P Philology. Linguistics |
Departments: | Faculty of Arts & Social Sciences > Linguistics & English Language |
ID Code: | 50928 |
Deposited By: | ep_importer_pure |
Deposited On: | 03 Nov 2011 12:25 |
Refereed?: | No |
Published?: | Published |
Last Modified: | 07 Jan 2015 22:44 |
Identification Number: | |
URI: | http://eprints.lancs.ac.uk/id/eprint/50928 |
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text:
hahahaahaha that article is hilarious, it actually cracked me up. I just saw it now. At approximately 3:00PM, sources say Hernandez asked Tebow for his phone to place a call to Bill Belichick to inform him Tebow's refusal to change position, Tebow tossed Hernandez his phone missing Hernandez four feet away from him, instead hitting the home security panel and destroying everything (have you seen him try to throw a football, very believable) The Patriots refused to comment on the situation but Rex Ryan, who never refuses to comment on anything told Daily Snark "Man he's catching on great with the Patriots, learning to destroy footage that quickly." Stay tuned for more on this story! (i dont say this often - or maybe ever - but rex, high five. i actually cracked up after reading this part too) -- I'm not familiar with the link or website though, u sure this isn't a hoax?
hilarious... you can't buy that kind of humer.... I actually laughed so hard, for real, tebow four feet off when throwing a phone and rex with the destroying footage comment - again, all just too much..
Why is this thread back? This article was so unfunny that I didn't even crack a smile... and my dumbazz decided to re-read it just now. I had the same reaction. Terrible.


text:
What does PG3 stand for?
What does PG3 mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: PG3.
We've found a total of 1 definition for PG3:
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PG3 | third postgraduate year |
Still can't find the acronym definition you were looking for? Use our Power Search technology to look for more unique definitions from across the web!
"PG3." Abbreviations.com. STANDS4 LLC, 2015. Web. 26 Apr. 2015. <http://www.abbreviations.com/PG3>.


text:
17 CFR 210.3-06 - Financial statements covering a period of nine to twelve months.
Except with respect to registered investment companies, the filing of financial statements covering a period of 9 to 12 months shall be deemed to satisfy a requirement for filing financial statements for a period of 1 year where:
The issuer has made a significant business acquisition for which financial statements are required under § 210.3-05 of this chapter and the financial statements covering the interim period pertain to the business being acquired; or
Where there is a requirement for filing financial statements for a time period exceeding one year but not exceeding three consecutive years (with not more than 12 months included in any period reported upon), the filing of financial statements covering a period of nine to 12 months shall satisfy a filing requirement of financial statements for one year of that time period only if the conditions described in either paragraph (a), (b), or (c) of this section exist and financial statements are filed that cover the full fiscal year or years for all other years in the time period.
[54 FR 10315, Mar. 13, 1989]
Title 17 published on 2014-04-01
no entries appear in the Federal Register after this date.


text:
With Instructables you can share what you make with the world and tap into an ever-growing community of creative experts.
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This is part of the Offa's Dyke path, which leads up to Hergest Ridge, in our neighbouring sister county, Herefordshire. This is an old drover's path and it becomes beautifully broad and inviting as you proceed up and along it.
It's a nice gentle climb to the top, just right for out of condition types like ourselves and even better - a bench handily situated halfway up.
Where one can study the map and try to work out where the heck we are in relation to everything.
We like to know where we are in a landscape Just beyond the hills, a dim blue hump on the horizon, we spot Caer Caradoc, whose more taxing slopes we went up the other week. Now we can place ourselves. There's Shropshire, just a few miles away -
- and there's two humped Caer Caradoc, the furthest hill we can see, keeping a watchful eye on us, in case we stray too far.
If you recognise the name 'Hergest Ridge', then you may be thinking of the Mike Oldfield album of the same title. It was written round about here, and somewhere in our packed up things I have the original vinyl, picked up second hand when I was about seventeen, so visiting the actual place was a landmark journey for me.
We made our way to the flattened top, where the winds whistle and sheep graze quietly with ponies. Then we strolled back down hill, finding shelter behind a big gorse bush where we could eat in peace - the local cheeses we bought in Ludlow a few hours earlier - Wrekin White, Monkland and Ludlovian Cheddar. With ripe Victoria plums and water. Apart from the ciabatta (although also locally baked) it was about a traditional a picnic as we could wish for.
We ate overlooking the heart of England - which may look like a flat bit of land here, but there across are the Malvern Hills and beyond them unseen, the Cotswolds, our old stamping grounds. Back then, we would see them and imagine Herefordshire and Shropshire behind them, wondering if one day we'd be living on the other side. Border country.
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Labor Day Report Shows Why Energy Reform Must Become National Policy
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Introducing the First Contactless MasterCard for Small Business
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New Texas Margin Tax -- Business or Income Tax
Candidates for governor in Texas last week reacted to the Financial Accounting Standards Board's (FASB) conclusion that the new Texas margin tax was an income tax under Financial Accounting Standards (FAS) 109 "because the tax is based on some measure of income." FASB declined to set up a project to give advice on the matter.Kathy Walt, spokeswoman for Republican Governor Rick Perry, and former state Comptroller Democrat John Sharp, who headed the commission that recommended the tax, said that FASB was providing instructions for accounting purposes only, according to the Houston Chro
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The Supreme Court also closed the book on one of the last of the Truman Administration scandals last week: it refused to review the convictions of Matthew J. Connelly, appointments secretary to President Truman, and Theron Lamar ("Sweet Thing") Caudle, Assistant Attorney General in charge of the Justice Department's tax division. They were fined $2,500 and sentenced to two years in prison each for conspiring to fix a tax case during their days in power. Although Connelly and Caudle can ask the Supreme Court to reconsider, their chances are indeed remote.
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Teva Pharmaceutical Industries Ltd. (NYSE: TEVA) announced today the termination of its collaboration with CureTech Ltd.
"We are in the process of conducting a disciplined review of our pipeline. As we looked closely at CT-011 and the most recent clinical and biochemical data, we have made the strategic decision to invest our resources elsewhere where we can have the most impact for patients," stated Dr. Michael Hayden, President and CEO of R&D and Chief R&D Officer.
CT-011 is a humanized monoclonal antibody being developed as a treatment for hematological malignancies and solid tumors. CT-011 was assessed in several phase I and II clinical studies in various cancer indications including diffuse large B-cell lymphoma (DLBCL), colon cancer, metastatic melanoma and additional investigator initiated studies.
Teva entered into agreements with CureTech in 2006. Teva intends to book a noncash net charge of $109 million as a result of the impairment of its investment in CureTech.
Teva Pharmaceutical Industries Ltd.
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Misra, Amalendu (2004) Theorising "small" and "micro" state behaviour using the Maldives, Bhutan and Nepal. Contemporary South Asia, 13 (2). pp. 133-148. ISSN 0958-4935
Full text not available from this repository.Abstract
The aim of this paper is to examine the normative justification of 'small' and 'micro' state behaviour. Whatever theoretical position one assumes in order to examine the issue of small state performance, some pertinent facts appear fairly consistent including their vulnerability to external forces, inability to interact effectively with the outside world, and relative backwardness. Adopting a comparative approach for the consistent elaboration of the analysis, this article concentrates on Bhutan, Nepal and the Maldives. Its focused comparison ensures that both the specificities and the generalities are addressed in all three cases. Using the Weberian notion of 'patrimonialism', this study highlights the peculiar 'power politics' that is prevalent in these polities, and shows how it dominates the discourse on democracy. By cross-examining various developmental theories, its also asks whether there is any basis to the axiom that 'small states are generally backward' and destined to remain so. The overwhelming picture that emerges from this investigation highlights the facets of state failure. The paper concludes with an assessment of the place and context of small state in a globalised world.
Item Type: | Article |
Journal or Publication Title: | Contemporary South Asia |
Subjects: | J Political Science > JA Political science (General) |
Departments: | Faculty of Arts & Social Sciences > Politics & International Relations (Merged into PPR 2010-08-01) |
ID Code: | 35572 |
Deposited By: | Mr Richard Ingham |
Deposited On: | 24 Jan 2011 13:42 |
Refereed?: | Yes |
Published?: | Published |
Last Modified: | 11 Mar 2015 09:30 |
Identification Number: | |
URI: | http://eprints.lancs.ac.uk/id/eprint/35572 |
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Could a mandated food additive aimed at better fetal development be a risk for seniors?
... fortify with folic acid to better assure that all babies are born healthy, the government should also encourage deficiency screening of the elderly to ascertain that such laudable efforts do not come at the expense of inadvertent harm to others....U.S. News & World Report ranks The Children's Hospital of Philadelphia the top pediatric center
...ically advanced, multidisciplinary care for unborn babies with genetic or anatomical abnormalities. Center physicians are considered pioneers in the innovative field of fetal surgery....Thymus transplant might save babies born without immune systems
...red the procedure to transplant thymus tissue into babies with DiGeorge Syndrome to enable their bodies to l...geons to expose the heart. Markert asks parents of babies undergoing heart surgery for permission to use any discarded thymus tissue to help a child with DiGe...Scientists develop greater accuracy in recording babys heart rates in the womb
...gy organisation, to study the heart rate of unborn babies in minute detail. The technique, reported in this months British Journal of Obstetrics and Gynaecology, will allow doctors to monitor the health of babies' hearts and obtain the full fetal ECG (fECG), particularly during high risk pregnancies, such ...Babbling key to evaluating speech development in babies with hearing loss
... a result, within the first two years of life more babies and toddlers are receiving hearing aids or cochlear implants, which are surgically implanted electronic devices that process sound and directly stimulate the auditory nerve. "More than 40 states now implement universal infant hearing screenings, so t...Clinical study of Penn State Hershey technology begins in South Africa
...se the chest wall stabilizer, a device that allows babies with respiratory distress to breathe easier. "Although the device could be an option for babies who need help with breathing in technologically-advanced hospitals like those in the United States, ...Scientists shed new light on speed of infant learning
...postulate that object knowledge could be something babies are born with. But new research by a team of psych...e unobscured trajectory. The team also found that babies who were six months of age had already grasped the fundamentals of object concepts, suggesting that ...Dental procedure may reduce risk of premature birth
...ording to new study findings. Nearly 12 percent of babies in this country are born preterm (before 37 completed weeks of pregnancy), which increases their risk of death and lasting disabilities, such as mental retardation, cerebral palsy, lung and gastrointestinal problems, and vision and hearing loss. The ...UCSD researchers identify chromosome location for 2nd form of Joubert syndrome
...normal breathing pattern called hypernea, in which babies pant; abnormal eye and tongue movements; and mild or moderate retardation. The type of Joubert syndrome now traced to chromosome 11 also includes eye or kidney problems, in addition to the classical symptoms associated with the disorder. "The hunt f...Nevirapine sustains advantage over AZT during breastfeeding period
... percent risk reduction for the NVP group when the babies were 6 to 8 weeks of age. The cost savings of usin...ime of greatest risk of HIV transmission. Although babies in both groups continued to acquire HIV throughout the study, they did so at approximately the same ...Further evidence for effectiveness of nevirapine in reducing mother-to-child HIV-1 transmission
...ntrapartum/neonatal zidovudine regimen when 87% of babies in the trial had reached age 14-16 weeks. The same...mothers up to six weeks after delivery and for all babies up to 18 months of age. From late 1997 to early 1999, HIV-1 infected pregnant women in Kampala, Ugan...Low and high birthweight increase risk of cerebral palsy
... cerebral palsy; at the other end of the spectrum, babies born in the top 3% range for birthweight have up t...esearch has indicated that low birthweight in term babies is associated with increased risk of cerebral palsy. Stephen Jarvis from the University of Newcastl...'Genetic switch' proves two mechanisms exist by which immune system cells differentiate
...ly erodes. This is one reason why older people and babies are frequently sickened by or die from diseases that cause little harm to those from their teenage years to midlife. Likewise, certain diseases can kill off T-cells, making the body vulnerable to a host of infectious diseases, almost as if their bod...Deadly decision: Where should baby sleep?
...ffocation that is as much as 40 times greater than babies who sleep in standard cribs, a Saint Louis Univers...trics. "The odds of death go up dramatically among babies who use adult beds," says James Kemp, M.D., one of the researchers and an associate professor of ped...Antiretroviral therapy after birth decreases mother-to-child HIV transmission
Antiretroviral therapy given to babies after birth offers protection against HIV infectio...researchers also report that giving these drugs to babies after birth is easier to administer when compared to giving antiretrovirals to mothers during pregna...Antiretrovirals reduce mother-to-child HIV-1 transmission when started after childbirth
...T highlight how antiretroviral therapy targeted at babies soon after childbirth (because their mothers' HIV ...ssessed whether nevirapine and zidovudine given to babies only reduced HIV-1 transmission more than nevirapine alone. Over 1100 babies of Malawian women with...Brain may 'hard-wire' sexuality before birth
...y offer physicians a tool for gender assignment of babies born with ambiguous genitalia. "Our findings may help answer an important question -- why do we feel male or female?" said Dr. Eric Vilain, assistant professor of human genetics and urology at the David Geffen School of Medicine at UCLA and a pediatr...Resurgent rickets - Call for vitamin D supplementation for pregnant women and children
...ithout vitamin D supplementation, particularly for babies whose mothers are vitamin D deficient; reduced opportunities for production of the vitamin in the skin because of female modesty and fear of skin cancer; and the high prevalence of rickets in immigrant groups in more temperate regions. Nick Bishop c...UK childhood blindness more common than previously thought
... diversity and greater survival of low-birthweight babies is contributing to a higher proportion of children...enced by the increased survival of low-birthweight babies and the susceptibility of children from ethnic minorities to certain ocular conditions. Jugnoo Rahi ...Scientists identify novel enzyme with key role in leukemia protein's normal function
...per. Mixed lineage leukemia strikes fewer than 100 babies every year in the United States, but it is typically fatal in 60 percent. It is caused by damage to the MLL gene, which then makes a mutant MLL protein. James Hsieh, MD, PhD, and Emily Cheng, PhD, are the paper's first and second authors, respectivel...


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20 apartments for rent in Polish Hill, Pittsburgh, PA
Waterford Nevillewood 1900 Tee Court, Presto, PA 15142 Map1 BR - 3 BR$1,020 - $1,660(412) 536-7828
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The Polish Hill neighborhood is the inspiration behind a published book generated by students called Polish Hill Remembered. Polish immigrants eager to work in the growing steel industry settled this community in the late 1800s. Nestled on a hill overlooking the scenic Allegheny River, the Polish Hills neighborhood is located in Allegheny County, Pittsburgh, Pennsylvania in the zip code area of 15219. Liberty Avenue borders the Polish Hill neighborhood to the north, Bloomfield Bridge to the east, Bigelow Boulevard to the south and 28th Street Bridge to the west.
The Polish Hill neighborhood is pedestrian friendly with sidewalks and accessible to public transportation. Students in the community can attend Robert Lee Vann Elementary School, Woolslair Elementary School, Arsenal Middle School, and Schenley High School. Carnegie Mellon University is just ten minutes away and features notable alumni such as Ted Danson, actor and television producer.
Several golf courses and parks are in the vicinity of the Polish Hill neighborhood such as Bob O'Connor Golf Course, Grand View Golf Club, South Hills Country Club and Oakmont Country Club. Within walking distance of the Polish Hill community, West Penn Recreation Center offers weight rooms, a swimming pool, basketball courts, and West Penn Field, a skate park. Schenley Park is eleven minutes away and offers a disc golf course, played with Frisbees, and picnic areas.
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Client | FLORIDA STATE UNIVERSITY |
Location | TALLAHASSEE, FLORIDA |
Completion | 2009 |
Area | 2,200 SQUARE FEET |
Contractor | CHILDER'S CONSTRUCTION |
This program called for the alteration of a Lecture Hall on the second floor of the Longmire Building, originally constructed as a movie theatre in the 1930s. The charge was to create a new combination smart classroom and performance theatre for the School of Music. The challenge was to incorporate the required modern classroom technologies, while enhancing the overall space. The existing splayed plaster accents around the large windows, the wood detailing around the room entrances and the majestic wood ceiling beams provided a great starting point. The new wall stops short of the existing ceiling while maintaining the arc profile of the exposed wood beams at the ceiling. This design of the new wall also included marker boards, concealed behind salvaged wood sliding doors that were hidden in the existing walls. Back-lighting and custom stain provide for an elegant combination of new and existing elements. The entire room and attic space were modified to enhance the overall acoustic quality. The attic was insulated, the mechanical system included double wall ducts and large plenums, the ceiling and reverse fan walls that form the pockets for acoustic curtains were installed were installed with multi-layered insulation to provide sound deadening, and the elevated seating floor was constructed with multiple layers of sound dampening sheathing. Since completion in Summer of 2009, the space has quickly become a favorite within the music school for piano concerts and small ensemble performances.


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How do I keep my application running in the background? Would I have to jailbreak my iPhone to do this? I just need this app to check something from the internet every set interval and notify when needed, for my own use.
Yes, no need to jailbreak. Check out the "Implementing long-running background tasks" section of this doc from Apple. From Apple's doc: Declaring Your App's Supported Background Tasks Support for some types of background execution must be declared in advance by the app that uses them. An app declares support for a service using its Info.plist file. Add the UIBackgroundModes key to your Info.plist file and set its value to an array containing one or more of the following strings: (see Apple's doc from link mentioned above.) |
Use local notifications to do that. But this will not check every time. You will have to set a time where you will check your specific event, you may shorten this by decreasing your time slot. Read more about local notification to know how to achieve this at: |
I guess this is what you required When an iOS application goes to the background, are lengthy tasks paused? iOS Application Background Downloading This might help you ... Enjoy Coding :) |
I know this is not the answer to your question, but I think it is a solution. This assumes that your trying to check something or get data from the internet on a regular basis? Create a service that checks the internet every set interval for whatever it is you want to know, and create a push notification to alert you of it, if the server is down, or whatever it is your trying to monitor has changed state. Just an idea. |
Yes you can do something like this. For that you need to set entry in info.plist to tell os that my app will run in background. I have done this while I wanted to pass user's location after particular time stamp to server. For that I have set "Required background modes" set to "App registers for location updates". You can write a handler of type UIBackgroundTaskIdentifier. |
You can already do this in the applicationDidEnterBackground Method |