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Population Pharmacokinetic-pharmacodynamic (PK-PD) Modeling of Co-administered Gabapentin in Neuropathic Pain
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The primary objective of this study is to develop a pharmacokinetic (PK) and a pharmacokinetic-pharmacodynamic (PK-PD) model for gabapentin in patients with neuropathic pain.
The secondary objectives are to investigate whether adjuvant therapy of venlafaxine or donepezil contributes to 1) improved analgesic efficacy and 2) improved health-related quality of life (assessed by the SF-36 questionnaire) in neuropathic pain patients treated with gabapentin.
Condition | Intervention | Phase |
Post-traumatic Neuropathic Pain |
Drug: gabapentin and venlafaxine Drug: gabapentin and donepezil |
Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Randomized Endpoint Classification: Pharmacokinetics/Dynamics Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment |
Official Title: | Population Pharmacokinetic and Pharmacodynamic Modeling of Gabapentin in Neuropathic Pain - Effect of Adjuvant Pharmacotherapy |
- Pain intensity scorings on Numerical Rating Scale (NRS). Plasma concentrations of gabapentin. [ Time Frame: 0 - 8 hours follwing dose intake of gabapentin. during steady state ] [ Designated as safety issue: No ]
- Health-related quality of life assessed by SF-36. Pain according to McGill Pain Questionnaire. [ Time Frame: Minimum 6 weeks following initiation of gabapentin and combination therapy, respectively ] [ Designated as safety issue: No ]
Estimated Enrollment: | 30 |
Study Start Date: | August 2009 |
Study Completion Date: | September 2011 |
Primary Completion Date: | April 2011 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
Active Comparator: Gabapentin + venlafaxine |
Drug: gabapentin and venlafaxine
Week 1-6: Gabapentin monotherapy (titration to individual maximum tolerated dose or maximum 800 mg 3 times daily). Week 7-12: Venlafaxine 75 mg once daily is added. |
Active Comparator: Gabapentin + donepezil |
Drug: gabapentin and donepezil
Week 1-6: Gabapentin monotherapy (titration to individual maximum tolerated dose or maximum 800 mg 3 times daily). Week 7-12: Donepezil 5 mg once daily is added. |
Detailed Description:
Neuropathic pain is estimated to affect 2-3 % of the population and the condition is difficult to treat with conventional analgesics. The drug of first choice is typically a tricyclic antidepressant drug (TCA) or the antiepileptic drug gabapentin. TCAs have well-documented effects, but the use is commonly interrupted due to intolerable adverse effects. Gabapentin, on the other hand, is generally well tolerated in patients. Clinical trials have proven that gabapentin is efficacious for neuropathic pain of various origins. Nevertheless, monotherapy is seldom sufficient for the management of severe neuropathic pain. Combination therapy, e.g. of gabapentin and an analgesic with complementary mechanism of action, may be a rational strategy to obtain improved results at lower doses and with fewer side effects. Although many neuropathic pain patients receive a combination of drugs, there is an absence of clinical evidence for optimal drug combinations.
Gabapentin binds to the alpha-2-delta subunit on presynaptic voltage-gated calcium channels, which results in modulation of the release of neurotransmitters from presynaptic nerve terminals. Recent studies in animal models of neuropathic pain have shown that gabapentin is effective on supraspinal structures, to activate the descending pain inhibitory noradrenergic-cholinergic cascade. Thus, it might be possible to potentiate the analgesic effect of gabapentin by concomitant administration of a drug able to prolong the action of noradrenaline or acetylcholine in the synapse cleft. In this study, the adjuvant effect of the noradrenaline and serotonin reuptake inhibitor venlafaxine and the cholinesterase inhibitor donepezil will be investigated in neuropathic pain patients treated with gabapentin.
The study consists of two periods. All patients are treated with gabapentin in the first period, and receive randomised adjuvant therapy of venlafaxine or donepezil in the second period. Repeated pain intensity ratings and blood samples for analysis of gabapentin plasma concentrations will be collected over one dosing interval of gabapentin at the end of each period.
Data will be analysed by means of nonlinear mixed effect modeling. The NONMEM programme will be used to develop models describing the PK and the PK-PD relationship of gabapentin in patients with neuropathic pain. The potential effect of concomitant treatment with venlafaxine or donepezil will be evaluated by covariate analysis in the developed PK and PK-PD models of gabapentin.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Diagnosis of post-traumatic neuropathic pain
- Spontaneous pain intensity ≥ 40 on VAS or ≥ 4 on NRS
- Man or woman ≥ 18 years old
- Informed consent to study participation
Exclusion Criteria:
- Presence of other type of pain as strong as or stronger than the neuropathic pain
- Impaired kidney function (GFR < 30 ml/min)
- Uncontrolled cardiovascular disease/hypertonia
- Uncontrolled narrow-angle glaucoma
- Uncontrolled pulmonary disease
- Epilepsia
- Pregnancy
- Nursing
- Woman of childbearing potential not using contraception or planning to become pregnant during the study period
- Disability to understand and cooperate with study procedures
- Allergy to study medications
- Concomitant participation in other clinical study
Please refer to this study by its ClinicalTrials.gov identifier: NCT00967707
Sweden | |
Multidisciplinary Pain Centre, Uppsala University Hospital | |
Uppsala, Sweden, 75185 |
Principal Investigator: | Stephen H. Butler, MD | Uppsala University |
No publications provided
Responsible Party: | Uppsala University |
ClinicalTrials.gov Identifier: | NCT00967707 History of Changes |
Other Study ID Numbers: | GBPPKPD-09, EudraCT number 2009-010783-41 |
Study First Received: | August 27, 2009 |
Last Updated: | October 11, 2011 |
Health Authority: | Sweden: Medical Products Agency Sweden: Regional Ethical Review Board |
Additional relevant MeSH terms:
Neuralgia Nervous System Diseases Neurologic Manifestations Neuromuscular Diseases Pain Peripheral Nervous System Diseases Signs and Symptoms Donepezil Gabapentin Gamma-Aminobutyric Acid Venlafaxine Analgesics Anti-Anxiety Agents Anti-Dyskinesia Agents Anticonvulsants |
Antidepressive Agents Antidepressive Agents, Second-Generation Antimanic Agents Antiparkinson Agents Calcium Channel Blockers Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants Cholinergic Agents Cholinesterase Inhibitors Enzyme Inhibitors Excitatory Amino Acid Agents Excitatory Amino Acid Antagonists GABA Agents Membrane Transport Modulators |
ClinicalTrials.gov processed this record on April 23, 2015


text:
Alarming News: I like Morgan Freeberg. A lot.
American Digest: And I like this from "The Blog That Nobody Reads", because it is -- mostly -- about me. What can I say? I'm on an ego trip today. It won't last.
Anti-Idiotarian Rottweiler: We were following a trackback and thinking "hmmm... this is a bloody excellent post!", and then we realized that it was just part III of, well, three...Damn. I wish I'd written those.
Anti-Idiotarian Rottweiler: ...I just remembered that I found a new blog a short while ago, House of Eratosthenes, that I really like. I like his common sense approach and his curiosity when it comes to why people believe what they believe rather than just what they believe.
Brutally Honest: Morgan Freeberg is brilliant.
Dr. Melissa Clouthier: Morgan Freeberg at House of Eratosthenes (pftthats a mouthful) honors big boned women in skimpy clothing. The picture there is priceless--keep scrolling down.
Exile in Portales: Via Gerard: Morgan Freeberg, a guy with a lot to say. And he speaks The Truth...and it's fascinating stuff. Worth a read, or three. Or six.
Just Muttering: Two nice pieces at House of Eratosthenes, one about a perhaps unintended effect of the Enron mess, and one on the Gore-y environ-movie.
Mein Blogovault: Make "the Blog that No One Reads" one of your daily reads.
The Virginian: I know this post will offend some people, but the author makes some good points.
Poetic Justice: Cletus! Ah gots a laiv one fer yew...
You knew it was out there somewhere…I know I did. But I'm still surprised at the length that results. Although I suppose I shouldn't be.
Ka-pow, zowee.
Holy Wholes!
- Kini | 01/31/2011 @ 22:29Leave a Reply
You must be logged in to post a comment.

subset: commoncrawl


text: Publications Search Results Users may wish to consult What's Included in the Bibliography. Results 1 - 1 Results per page: 25 50 100 Sort by: Pub Date (newest) Title Recent Additions Author Clear All Pub. Year Citation 2007 Haas, Steven A. The long-term effects of poor childhood health: An assessment and application of retrospective reports. Demography. 44, (1), 113-135. Full Text Options: DOI Worldcat Google Scholar Export Options: RIS EndNote XML [1]


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There goes another one http://www.bbc.co.uk/sport/0/football/20423905 Chelsea sack Roberto Di Matteo after Champions League defeat Manager Roberto Di Matteo has parted company with Chelsea, the club has announced. The word, according to the little woman who doesn't really follow football but caught the TV report, is it's gonna be either Benitez or someone called Pepsi Guatamala. That last one sounds like he knows what he's doing so I say, let's go for him
This is probably the most premature sacking yet. He's simply had a bad series of games, and unless he has lost the dressing room (we haven't heard any indications suggesting this), then there's no reason to have sacked him. Abramovich should have given him time to weather the storm and right the ship. My feelings are that a) he was just being used as a temporary stop-gap before they got a hold of a more "prestigious" manager, and b) it's not only the loss, but the fact that he didn't start Abramovich's pet Fernando Torres that may have compounded to his already existing woes. Imo, (and of course this is sheer speculation) RDM was clearly intent on making a statement last night, and by doing so undermined Abramovich's authority. The fact that his tactics blew up in his face made the decisions of the higher ups all the more easier. I called it unfortunately, though I didn't think it would happen after this game, but possibly after the Man City one. It's an unfortunate move by the club, and one that could not have been executed with the most careful consideration. This isn't how you treat someone who delivered an unprecedented Champions League and FA Cup double for the club. Oh, well, the thought of Rafa Benitez driving our club towards middle-table obscurity is a frightening possibility. Hopefully, it ends up being Guardiola.
Or possibly the other fella TLW mentioned Anyway, yeah, you're right. Very premature IMO. This year was ALWAYS going to be a transitional one and with stalwarts like Drogs gone and both JT and Frank unavailable, (apparently), for game after game, the fact we've dropped down the pecking order isn't THAT much of a surprise.
You gotta say one thing though, supporting the chels, it ain't boring, is it! It rather reminds me of that soap opera TLW watches, 'Eastenders', where the drama comes mainly from the fact it's a fecking catastrophe followed by an unmitigated disaster with the odd bright spot in between coz otherwise, it would get a bit boring
So like I usually do when I start up my computer is to check some footy news and come to know that Robbie is sacked. That escalated quickly...
I hope everyone realizes this would be a huge gamble. Never managed outside of Spain. It's not a given he will adapt well to another league and/or another style of playing. Benitez is probably the safest short-term stopgap.
This is a real disgrace I am deeply ashamed to be a chelsea supporter. If it is the ex Liverpool beared wonder I will be there at the next game booing and singing there is only one De Matteo
I don't know about Benitez but I agree that Pepsi Guatemala, as he will remain for me until something happens to change my opinion, (i.e. wins the league, FAC, LC and CL in the same season), is a gamble, I'm not sure what the thinking is behind it but, tbh, I tend to think that thinking and the chels don't go together that well these days Having said that, (and I've said this before many times on here), I'll still be here after the new manager, (whoever it is), the current players and even Abramovich, are LONG gone.
What the hell? One month of bad results and he is gone? If rafa comes in, it will be my worst nightmare....
Well, I've got a few worse than that but, tbh, I just don't see what someone new is going to do that's THAT different from what Robbie will do in the short term and if it's the long term what's the point of the sacking NOW?!!!! Bottom line is, (and I said this before he was given the job), who is there that can GUARANTEE better results. Mid you, there is one fella that knows the league well and gets the fellas up for the battle. I think we all know who I'm talking about, don't we?!
Wow. Shocked and disappointed. Sacking any manager in these circumstances would be ridiculous, but after what RDM accomplished last season... Really struggling to wrap my head around this, tbh. Makes it seem like the club wasn't really happy with appointing RDM this summer and were just waiting to pull the trigger. Edit: I really, really hope this isn't a "bring in Benitez to get the best out of Torres" scenario.
Unbelievable. Its not April is it? Who would have thought Sparky would still be with a job and Di Matteo out of one by the end of this week? I know its a bit shocking seeing a team with so much attacking talent and massive investments more than likely out of the CL in the group stages after winning in it, but surely Di Matteo was going to get a full season? Nope. This type of sacking means that someone has been lined up. I hope to god that's not the case. I hope Roman isn't embarrassed for wasting more of his money on another love toy, only to be disappointed. Even if it helps Torres regain form, I couldn't stand having that fat lard faced prick as Chelsea manager.
what message does this send to the players? its not your fault- it is on the gaff(ers) no accountability, none
the media are kicking around his name along with Rafa and Sheva because there will be no issues with Sheva the club allegedly have an annoucement coming
I get the feeling the club didn't want RDM but had to give him a fair shake when he won CL and FA Cup. It's like Roman's taking advice from Moratti and Zamparini on how to handle managers. And now we have the possibility of ending up with Rafadyce. I know Roman's the owner, but honestly he acts like that guy who rage quits in FIFA when he gets a bad run of results.


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GardenAntqs. Now at Marburger Farm |
Sunday, September 23, 2012
Round Top Antique Week Fall Shows 2012
Who's going? Who's never been? Who has it on their bucket list? Who wants more information about what it is and how to best navigate the miles of tents, barns and pastures that make up this wonderful bi-annual event that makes up Round Top/Warrenton/Margurger Farm and the many other shows that are Antique Week?
I get asked about Round Top all the time and even though I've gone to the shows for years, it's almost impossible to describe how big it is and how it works.Wanna know how big it is? Well, I always say it's three weeks big.
It would be nearly impossible to see it all. New shows and venues are being added every show and it's grown exponentially since it began. Here's the biggest insider secret I can share with you....it's happening right now. No matter what any schedule you are looking at says, if you get in your car right now and head that way you will get to do some shopping. If there's a specific show you like, check the schedules (info below) and plan your trip for that day.
These images are from my trip to Antique Week earlier this year for the spring shows:
The Show Daily is the shoppers and dealers Bible during Antique Week and can help you plan your trip.
And, don't forget that the latest issue of Souvenir Magazine has an article written by yours truly, with more information and links than you can shake a sausage on a stick at. So you should read that, too, before you go :)
6 comments:
This girl from The Woodlands is going up on the 5th, staying in Waller (no good places left in Brenham) then going back by myself on Saturday. Clean up run. Looking forward to getting in Warrenton as Marburger takes us all day Friday. So ready, wish I didn't work!! Can't wait to see what you score!
ReplyDelete- Anonymous24/9/12 18:19
Thank you again for including my booth when I was at Zapp Hall (the pic with the white chair and pitchers). I'll see you now that I'm at Marburger Farm, Theresa (http://gardenantqs.blogspot.com/)
ReplyDelete - Anonymous11/3/13 09:52
If you're still trying to find a place to stay you can visit www.TexasAntiqueFest.com. Under their Lodging tab it will display all the area B&Bs on a Google map along with contact info. There may still be vacancy?
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BEGIN:VCALENDAR VERSION:2.0 CALSCALE:GREGORIAN PRODID:iCalendar-Ruby VERSION:2.0 BEGIN:VEVENT DESCRIPTION:
Using geometry as a way to structure ephemeral sensations of light and air\, Rachael Wren's work creates a sense of place and atmospher e. The dense spaces in her paintings are inspired by moments in the natural world when edges seem to disappear and atmosphere becomes all-encompassing -- due to fog\, snowfall\, overpowering sun\, or fading light at the end o f the day. At these times\, form and air mingle\; space feels thick and has a presence as tangible as that of solid objects. To capture these sensatio ns in her work\, Wren weaves together marks of subtly shifting color\, buil ding up space through an interplay between a geometric system that anchors the work and a shimmering light that allows it to vibrate and breathe.
\ nUnderlying Wren's work is a concern with perception\, with how the eye and mind process visual experience\, often in surprising ways. The same co lor can look quite different in two parts of a painting and illusions of co mplete\, volumetric forms can emerge from configurations of discrete\, flat marks. Although it is clear to see how each piece of color was laid down\ , and thus how each painting was made\, something enigmatic remains in the combination and cohesion of elements. In this way\, her work makes viewers aware of the mystery and complexity of seeing.
\nRachael Wren receiv ed a BA from the University of Pennsylvania and an MFA from the University of Washington. Her work has been exhibited in shows at Jeff Bailey Gallery\ , Geoffrey Young Gallery\, The Painting Center\, the Weatherspoon Art Museu m\, and the Fosdick-Nelson Gallery at Alfred University\, among many others . Rachael is the recipient of the Julius Hallgarten Prize from the National Academy Museum and an Aljira Fellowship. She has been awarded residencies at the Saltonstall Foundation\, the Byrdcliffe Art Colony\, the Vermont Stu dio Center\, the Anderson Center\, and the Artist House at St. Mary's Colle ge of Maryland.
DTEND:20130518 DTSTAMP:20150419T093424 DTSTART:20130423 GEO:40.75111;-74.004475 LOCATION:The Painting Center\,547 West 27th Street Suite 500\nNew York\, NY 10001 SEQUENCE:0 SUMMARY: Square Roots\, Rachael Wren UID:270447 END:VEVENT BEGIN:VEVENT DTEND:20130425T200000 DTSTAMP:20150419T093424 DTSTART:20130425T180000 GEO:40.75111;-74.004475 LOCATION:The Painting Center\,547 West 27th Street Suite 500\nNew York\, NY 10001 SEQUENCE:0 SUMMARY: Square Roots\, Rachael Wren UID:270448 END:VEVENT END:VCALENDAR


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"The citizen became concerned when Ms. Locklear exited her vehicle and stumbled into the traffic lane...the citizen called 911 and reported the entire incident to CHP Ventura Dispatch."The report goes on to state when officers arrived Locklear appeared disoriented, and after giving her a DUI test they determined it was not alcohol.
"Although obvious impairment was exhibited during the tests, alcohol was ruled out as a factor."Locklear was arrested for suspicion of driving under the influence and taken to the Santa Barbara CHP office.
"She was evaluated by a drug recognition expert, who concluded Ms. Locklear was under the influence of a controlled substance, and could not safely operate a motor vehicle."[E! Online]


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Official Website of the New York City Department of Parks & Recreation
Photo Gallery > General view of playground
Back to Photo Gallery
Description:Courtesy of New York City Parks Photo Archive, Neg. 20714
Location: Brower Park, BrooklynDate: September 28, 1941
Brower Park Playgrounds
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COLUMBIA — State Representative Chris Kelly, D-Columbia, came to the microphone in defense of Columbia City Council members during a town-hall style discussion Thursday evening about the establishment of an enhanced enterprise zone.
"There's nobody on the City Council who ought to be recalled," Kelly said, referencing efforts by the civil liberties group Keep Columbia Free to recall First Ward Councilman Fred Schmidt. "That's probably why they're not here. They're pissed off."
From the audience of more than 60 people, someone asked, "Why?"
"I'm telling you how I would feel," Kelly said, adding that council members had good intentions in supporting the EEZ.
"They don't listen to us," another audience member commented.
After a few moments of back and forth with audience members, the tension broke after Kelly asked, "Who's us?"
Nestor Mackno, an Occupy CoMo member, shouted, "the 99 percent," and laughter broke out.
"I'm just giving you my opinion as someone who's represented this community," Kelly said before Monta Welch took control of the microphone and urged calm. Welch, a Columbia Climate Change Coalition member, moderated the discussion.
The event at the Columbia Public Library featured speaker Greg LeRoy, the executive director and founder of Good Jobs First. His organization supports government and corporate accountability in economic development. He spoke strongly against the effectiveness of an enhanced enterprise zone and urged instead the use of more targeted incentives for individual businesses.
LeRoy said tax incentives such as an EEZ would not change the behavior of businesses.
An EEZ is a state tax incentive program for areas declared blighted that also provides for local property tax abatement. The City Council recently re-established an advisory board to work on an application to create an EEZ.
"All state and local taxes combined come to just over 1 percent of their total cost structure," LeRoy said. "Tiny, tiny changes in the cost of labor or energy would dwarf any changes in taxes."
Karl Skala, a former council member, also spoke and answered audience questions. He read the definition of blight according to the state of Missouri and said he was worried about the psychological effects of labeling an area blighted.
"If you really want a protection against blight, we need to change the city charter," Skala said.
Concern about the blight designation and the EEZ initiated the recall efforts of Keep Columbia Free. Mitch Richards, the treasurer of the group, spoke during the question-and-answer period and invited people to sign the recall petition.
"I guess I just wanted to point out that the recall option is in the city charter for a reason," Richards said, referencing Kelly's comments. "No one supports this but the people in power."
Kelly clarified his earlier remarks later in the discussion and said they were directed at the recall efforts only.
"My comments before had nothing to do with the attack on the ordinance and everything to do with the attack on the personalities," Kelly said.
Many of the questions from the audience dealt with the issue of blight and the possibility of eminent domain abuse. Tyree Byndom, a community activist, said he was encouraged by the discussion. Although he's opposed the blight designation, he said he's starting to see the other sides of the issue.
"I'm willing to compromise, and that's saying a lot," Byndom said. "I felt that this gave us some answers."
Mackno said the discussion demonstrated that most Columbia residents oppose the blight designation that would be required to establish an EEZ.
"I think most people are against the blight," Mackno said.
The event was sponsored by Citizens InVolved and InVested in Columbia, Keep Columbia Free, the National Organization for Women, the Mid-Missouri Women's International League for Peace and Freedom and the Columbia Climate Change Coalition.
Supervising editor is John Schneller.


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Re: mathgl3d
Hi, the online-help say "MVDepthGraphics[fmt] returns a graphics object with the depth buffer \ depending in fmt the depth is tranfromed into ChromaDepth colors. The format \ may be RGBColor for black background ChromaDepth images, CMYKColor for white \ background ChromaDepth images or GrayLevel for the plain depth buffer in 8 \ bit resolution." and so for a notebook with white background Show[MVDepthGraphics[CMYKColor]] Look into the MVManual, the section "Chroma Depth Images" has several examples. You can save the images directly from Mathematica with Export[ "a image format you like", MVDepthGraphics[CMYKColor], "The extension you need", ExportRaster->True ] Regards Jens Erich Neuwirth wrote: > > i am using mathgl3d, > the 3d open gl viewer for mathematica. > i manage some nice things already, > but i cannot find how i can produce the chromadepth graphics. > to create such graphics, one has to use a special palette. > i searched the documentation, > and i could not find a reference on how to create > such graphics. > > can anybody help me? > > -- > Erich Neuwirth, Computer Supported Didactics Working Group > Visit our SunSITE at http://sunsite.univie.ac.at > Phone: +43-1-4277-38624 Fax: +43-1-4277-9386


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Hello, I have a simple problem, that may be fixable. I have this 3D model of a creature, and he wears a cloth, for his pants, and its all on fine, but when i start the game, it goes to a different location(pops off), any idea how i can fix that? Pics below... 2nd picture is what happens, in game view. Any help will be appreciated, thanks!
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Are the pants a separate model with their own skeleton? If so you'll need to combine the meshes so the body and pants stay synced. See this thread for a great way to do that. PS. The title of this question wins today's prize. They are parented to the model, with the bones.
May 02, 2010 at 08:55 PM
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Jak, this is what the hierarchy looks like... It's a little hard to tell there but When you animate it in Max or whatever do the pants move with the creature? Also... Did you bring the pants into Unity separately and then drag them onto the creature hierarchy or did the import with the creature?
May 02, 2010 at 09:09 PM
They were with it when i imported the character from blender, i downloaded this character, it said fully rigged, and it came with the walk cycle, so im not sure haha
May 03, 2010 at 12:03 AM
I would suggest to try what Jak said, but is this really a problem in your game? I think that would be hilarious if the pants fell of a monster when its going to attack you! :D good luck solving the issue if you keep looking at it as a problem
Jul 01, 2010 at 09:11 AM
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BTW, how, and what did you use to create this? is it someone elses that u downloaded? That might be the problem?
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IDK how, but what I do know, is that is one good model!! Nice =] =P
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Landscape Architect Warren Byrd to Address School of Architecture Fall 2001 Lecture Series
November 12, 2001
WHO: Warren Byrd WHAT: Lecture: "Springs and Falls" WHEN: Friday, Nov. 16, 5 p.m. WHERE: Room 153, Campbell Hall
Warren Byrd, professor of landscape architecture at the University of Virginia, will speak at the School of Architecture Fall 2001 lecture series Friday, Nov. 16 at 5 p.m. in room 153 of Campbell Hall.
Bryds talk, "Springs and Falls," is part of the Deans Forum Lecture and will conclude the 2001 fall series, "Buildings and Grounds in Transition."
Chair of the University of Virginias Department of Landscape Architecture from 1986 to 1992, Byrd teaches studio design, and courses in plants and drawing. Byrd also is involved in an active private practice. His firm, Nelson-Byrd Landscape Architects currently is working on plans for Nikes European Headquarters in the Netherlands, a new panda exhibit for the National Zoo in Washington, D.C., the Sarah P. Duke Gardens at Duke University, the State Arboretum of Virginia, in addition to numerous other small and large projects across the United States.
The lecture is free and open to the public.
CONTACT: Joanna Gluckman, (434) 924-7116.
FOR ADDITIONAL INFORMATION: Contact the Office of University Relations at (804) 924-7116. Television reporters should contact the TV News Office at (804) 924-7550. SOURCE: U.Va. News Services
Top News site edited by Dan Heuchert (email@example.com); maintained by Karen Asher (email@example.com); releases posted by Sally Barbour (firstname.lastname@example.com). Last Modified: Tuesday, 13-Nov-2001 11:47:37 EST © 2001 by the Rector and Visitors of the University of Virginia Top News Information: (434) 924-7676.


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The National Begonia Society
Countdown 2012 to the South Coast Area Show & National Show Phil Champion
29th. July The South Coast Show - I prayed for a bit of sunshine to help me out, 2 days at 30 & 2 at 29 28°c respectively. Without it I would have been left counting the days till next year, many of my plants didn't make the day and could still have done with another week. The sun saved the day for me to get a few blooms on the bench. Morning of the show started with a lay in, I was out of bed at 4 am, it was hard to find enough blooms to take that were up to size (A) All the blooms looked even smaller than the day before, the blooms were all tucked up still asleep. Hopefully they would awaken on the journey down to the coast. The sat nav was set and I was on the road at 7am straight to the venue - no mess ups, Havant Garden Centre, I arrived at 8-20. A quick walk through to see where to go and there was the normal stalwarts Brian & Chrissie Simmons, Dave Coates & Norman Burgess. Soon found out that Pauline Coates had to stay and wait for a plumber, Dave was on his own so had to make sure he remembered where he put everything himself. Blooms were soon staged on the 6, 3 & 1 cut blooms boards. Bill Squibb was the last to arrive as usual. Roy the soft southerner had already staged his exhibit. With free tea & coffee laid on by the centre for the exhibitors I must say we were all made to feel very welcome by all the staff at the centre. Once all the exhibits were up and ready first panic set in - I had left my camera at home on our green garden waste bin in the garden, a quick phone call to the wife camera saved. Our judge for the day was Alan Harris, judging started on time ably assisted by 2 stewards Dave Coats & myself. It soon became apparent that the man Brian calls king was still going to keep his crown. Once the judging was over the in day was saved by the arrival of 3 or 4 cameras with lots of photos taken and 2 that I have never seen before at any show. Me personally managed to get a second with 1 bloom (B) & third in the 6 cut bloom classes (C), happy just to get blooms on the bench let alone any cards. Dave Coates took top honours with Brian Simmons second in the 6 cut blooms, I'll let Brian give the rest of the results. On the The Show page there are 2 special pictures one of all the exhibitors and the 2nd of the 5 entries in the 6 cut blooms with all the growers standing behind their blooms. Again many thanks to Havant Garden Centre, it was nice to see people's faces & asking the question "are they real". I would certainly like to go back again. On arrival home it was out with the old & in with the new (D), 2 weeks to the National.
Many thanks for your enthusiasm and dedication Phil, our Society could do with many more like you. Editor
Week 1 17th.June Week 2 24th. June Week 3 1st. July Week 4 8th.July Week 5 15th. July Week 6 22nd. July Week 8 8th. August Week 9 12th. August


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At Eric's suggestion, I visited CNN.com to see what might be news-worthy for the blog. None of the headlines grabbed my attention, the mother cat nursing a baby squirrel was sweet but not compelling, so I checked out this short video interview for my own entertainment: Laurence Fishburne's Daughter Enters Porn Industry. Porn is an easy mark for sensationalism, so I wasn't expecting any real 'news' here; after all, the lives of celebrities get a disproportionate amount of attention in our culture and that's not the Planet Waves game.
Why am I posting this then? Because I nearly fell over when I heard the contrast between Ms. Fishburne's poised, sex-positive, art-positive confidence and self-esteem and the (female) interviewer's measured attempts to undermine it. The news anchor begins by stating, "I'm not a prude […] I'm not afraid of sex, if it's part of art."
Really? Sex needs to be a part of art for you not to be afraid of it? And who exactly gets to decide what constitutes art? Montana Fishburne explains her view of porn as art, albeit a more graphic type of art, full of beautiful people touching each other in sensuous ways. To my ears, she clearly is doing this because she believes in what she is creating.
Given her father's career, we know she's not hurting for money or connections if she simply wants to become an actor. I don't know the family's dynamics, but her manner of speech does not seem to indicate an urge to 'get back at daddy' for anything.


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Sonia Kashuk Eye Palette
Sonia Kashuk Eye Palette Reviews
Sonia Kashuk Eye Palette Set
I have both of these collections, Perfectly Neutral and Sweet Nothings and I am really happy with both of them. The only drawback is the crummy little applicator, use a good brush instead. The shadows are very silky in texture, the palette has a nice eye shadow base that works really well for me. The shadows are buildable and blendable and last all day with no creasing, smudging, or fallout. T...read morehe colors in these palettes are very natural looking so if you are into brights these aren't for you, but I prefer more neutral looks so they work very well for me. They also are very affordable, and you don't have to use a lot of product to get a good effect. — 5 years, 4 months agoThis review is: Helpful | Not helpful | Inappropriate | 0 of 0 people said helpful
This review is: Helpful | Not helpful | Inappropriate | 1 of 3 people said helpful
Sonia Kashuk eye Palette (perfectly neutral)
I love this paletter!!!! if you want something neutral, office friendly, and of good quality, then you must try this palette. The color pay off is great and it comes with a eyeshadow base which is awesome. Not only do i use the base with the eyeshadows on the palette, but with any other. It's one one my favorite bases. If you are into packaging then you are going to love this. It is a very sturdy...read more and cute. I love it!! Alsp, the colors are very easy to blend. if you are a beginner in make-up, definitely try this palette!!! — 4 years, 6 months agoThis review is: Helpful | Not helpful | Inappropriate | 1 of 1 people said helpful


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It is difficult to imagine the devastation and suffering caused by Typhoon Haiyan. The process of rebuilding lives and homes will take years. Listed below are ways that you can help:
List of organizations assisting survivors
Philippine Relief Bake Sale
Battle for the Philippines
Filipino- American Association of Northern Illinois Fundraiser
Talent Showcase
Donations (Hygiene items, dry goods, clothes)
All donations will go to help relief efforts in the Philippines for the survivors of Typhoon Haiyan.


text:
Saturday, October 03, 2009
31 comments:
Well,we've watch the fed/gs/government manipulate and engineer the rally for the last 6 months,now we get to see whether they will be able to manipulate it (keep it under control)on the downside.
Well, if it follows the path of the Dow during that deflationary spiral of the 1930s it will lose 85.66% in the span of 22 months. Such a decline would leave the S&P500 somewhere in the neighborhood of 114 in July of 2011. That may seem overly dramatic, but that is history's lesson of what happens when you run the nation on a credit card.
We talk about a plunge, but looked at from afar, it was really a slow strangulation of the economy, which is exactly what this economy feels like to me. However, looked at from the ground, it appeared to be something completely different.
There is danger today for bull and bear alike. From an analytical perspective, it was only a -3.89% per month average decline. Incidentally, that matches the pace we've been on since Sept. 23rd, just a slow bleed. The actual experience for the individual investor in that two year period was a bit more dramatic. That is because it was a stair step decline with plenty of 50% retracements on that long slope of hope. That's where the danger comes in.
Investors in the 30s didn't see the reality of the situation with so many emotion charged rallies. The bears are in danger of holding through the rallies, which can be ruinous when they are so large. We just saw an example of that in March. The bulls obviously will suffer a similar danger if they mistake the rallies for another bull market. We hear that kind of delusional talk today.
All I'm saying is, Bull or Bear, if you don't expect the magnitude of this event to similarly affect the size of the retracements, you won't make any money on the decline because you may be left with only half your stake after each rally. Go through that process enough times, and you can go bust even though you got the overall direction of the market correct.
I'm bearish until the next rally. Don't make their mistake.
Smiddy - 8:09 AM
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Allan has given us the tools to figure this out. Use them for your financial security. - 8:46 AM
This is just Allan "crying wolf" again to support his own positions. We've heard and seen all these weird chars before and the market has gone straight up.
This is because WE ARE IN A RAGING BULL MARKET folks.
The trend is your friend and Allan at least used to support the book "Trend Following" now he has been anti-trend for the whole run up. Bullish only in NNVC which is ONE penny stock that has gone down.
OBAMA WON, NOT McCain.
MAKE MONEY! BUY BUY BUY BUY BUY with high leverage!
Sorry Doug, but you presented a pretty big stake of idiocy...
:-) alfaomega - 9:43 AM
Doug, I am a physician-friend of Allan's who also owned a small mortgage company. Let me respond to your statements:
Surely you are kidding.
Absolutely untrue. Because I treat a lot of people on the periphery of the economy I can state categorically that I saw these job losses coming 3-4 years ago and even said so to a number of people. While the job losses slowed down for awhile, they appear to have picked back up. Every day a patient or family member has lost a job. 3-4 families live under 1 roof (thank God for roofs!). Do NOT believe the Washington job numbers...they are an accounting manipulation.
I don't think so. Again, I'm in the business. I have not seen a big drop , and expect one, in mid-upper mid range house prices. When those low-mid level execs lose their jobs, look out. BTW no one is lending, for all practical purposes.
OBAMA WON, NOT McCain.
Got me on that one.
Agree and the statement works both ways.
Dr. Mo - 10:22 AM
- pimaCanyon said...
I wish you were right, I hope you're right, I want you to be right. Unfortunately there is plenty of evidence that suggests otherwise.
There are many ways to read the charts and the fundamentals. No one has a crystal ball. But the odds favor another big move down to at least a retest of the March lows. WHEN that happens is open to conjecture, but the charts indicate it has already started. Let's hope that a retest of the lows is as low as we go, and that we don't get the doomsday scenarios painted by many EW chartists. - 10:50 AM
Re: ATR Trailing Stop:
What inputs do you use for ATR period and ATR multiplication for the Metastock formula? - 10:51 AM
- Allan said...
confidence means not having to argue about your outlook for the future......
- curt504 said...
Anonymous re ATR, what is that system/ source of the signals. I know MC from Allan.
Doug, Some TX based real estate org released a paper last week saying there's 7 million dead beat homes stuck in the system right now inside zombie banks where the bank has no motivation to book the loss yet the homes are for all practical purposes on the shadow market. Many past due home occupiers are 12 months behind. When they get kicked out and have to fork out $1k / month for rent they'll spend even less. And this is just a rifle shot issue amongst a stinking mountain of other problems that are being over looked by you/the Media. Folks might also sub to Steve Peutz's letter email@example.com. Cheap $6 or $10/month and excellent reading for another view. Similar to Armstrong, another view. CNBC/Fox/US Gov are the last places we should get our econ data from.
Good luck, curt - 12:46 PM
Allan, Why are you so bullish on NNVC? Is there something you expect them to do with a big pharm company? I usually trade based on GET and BWT indicators, made an exception on this one and bought at $0.94, I do not intend to sell, however it's not my usual type of trade. In fact when it hit $0.76 on Friday I felt like Alfred E. Neuman, "What, me worry?" and bought some more. I'm taking the long term perspective here like Warren Buffet, my usual long-term is about 5 days. I would be interested in the info for setting up ATR as well. Thanks for your blog by the way, it is great! as is your analysis. Steve
- Allan said...
Steve: Do a Search of "NNVC" in the upper left hand corner, you will get everything I have written on the subject for the past 3-4 years.
- Charts and Coffee said...
My thoughts for the coming week.
I'm new to your blog and I look forward to stopping by on a regular basis. - 6:01 PM
Every wonder why there is so much effort to define this recovery? I keep hearing new terms being coined. I have heard it's an anemic recovery, green shoots, L shaped, blah, blah, blah. Has it occurred to you that people don't need to coin new terms when it is a real recovery? If we were in a real recovery, wouldn't the recovery itself be a given and conversation would turn towards something else, like the future, not the form the recovery seems to be taking? Wishful thinking? This smells suspiciously like people are trying to convince one another that a recovery is a fact. That says volumes about how precarious our economic state is today.
Smiddywesson - 6:17 PM
....thats right,Smiddy
No Plunge
This week next week or the week after. Not gonna happen. - 6:22 AM
- Background said...
Why is NNVC falling despite NanoViricides Secures $4.3M in Financing....am I missing something?
NNVC is all hat, no cattle. Based on Allan's reco's here I did my own DD and saw that there's really nothing of value there. Don't be a bag holder.
Well, one very disappointing issue with NNVC and Allan, is he has yet to be right about any of his short term price (chart) analysis, and its hard to see why he will be right about the long term, $100.00 plus.
- Allan said...
is he has yet to be right about any of his short term price (chart) analysis,
Another one with his head up his ass. Here is a link to my analysis (chart) made July 14, 2009:
With NNVC at 66c, I projected a target of 84c-1.00.
On August 10, 2009, NNVC printed 1.09. That's a gain of 70% in less then a month.
Now shower to get that crap off of your head and get back in the game. - 10:13 AM
gee Allan, you seem to forget all the price target you made at 1.85 short term?!
- Allan said...
Look, some jerk made the sweeping statement that I have never been correct in my short term forecasts for NNVC. It took me 10 seconds to find a short term forecast of mine that was spot-on.
I'm not saying they have all been perfect, it was the jerk who wrote that I, "have yet to be right." He is full of it.
If you want to take me on, get your facts right. - 11:25 AM
- Michael said...
Hey Anonymous, next time, save yourself and the rest us time by sparing your worthless post . The reality is that you keep coming back to read Allan's thoughts. Why is that? He shares his own opinions with everyone about his passion, something he is not obligated to do, and he owes us nothing.
I agree, Micheal. Add to that, he posts ANONYMOUSLY.....obviously not enough faith in his own words to put his name on it. Typical of those who enjoy taking down others to build themselves, and only themselves, up.
A flawed short term strategy IMO that inevitably results in self-destruction. (That odor you smell? Fear mainifesting as bitterness)
Allan, Carry on! You are much appreciated by those who have the wherewithall to appreciate your effort/sacrifice and have no ego axe to grind --just a desire to improve themselves (and those they support).
Carl - 1:59 PM
I'm not convinced that another 1.5% move up or down in a market like this proves anything at all.
Now, if you follow that up with some strength later in the week or the next, THEN we can have a productive argument, but I don't think it bouncing off resistance and remaining within the downward channel it's taken for the last two weeks is a very convincing bullish argument.
If it breaks strongly above 1050, I'll reconsider my timing, but it has to tell me I'm wrong before I change my opinions. I know that costs money, but it's part of the overhead of doing business.
Oh, yeah, I almost forgot: No recovery in sight, "This week next week or the week after. Not gonna happen."
..."if it breaks above 1050,I'll reconsider, etc"...I'm looking at that idea as well, but watching it play out, I'll be looking for not just a break back into the up channel above 1060...but Holding ...inside the channel...holding above ,lets say 1050 area...and establishing some sort of support range between 1000 and 1100
....through the time zone period of the next 4 weeks.
Its not just price point that matters...its also very important the TIME aspect of price movement.
I think if price stretches out in the coming weeks,holding at the 1060,with at least a hold above 1020(1000) level by the next lunar time point (go ahead and laugh,but look at all the tops and bottoms,starting with march 3)...if price holds up within this range ,at the 1060 area, with a bottom of 1020 holding up as support...by november 3 time area (alternate nov 17 area).... there might be no big wave 3 down....and the time factor would stretch the game out into the next month.
Still, hard to imagine no correction ??!?
Such a wave action,sliding sideways along the 1020 to 1060 range would suggest the development of a "wave 4" which redefines the whole rally wave from july 3 to sept 21 as a "wave 3" rather than a 'wave 5'
If that were to be the case...I would expect to see a break up thru 1080 and thru 1100 toward a target 1200 as the completion of wave 5.(starting at a bottom hold support in the 1020 area)
i.e. some kind of double or triple bottom,holding at the 1020-1000 area in the next 6 weeks...could recast the wave structure as a set up for a Wave 5 to target 1200 .
...Imagine what a collapse would look like from 1200 instead of 1080. only that much worse.
If this 'wave 5' scenario to 1200 happens...it would at least confirm that 5 waves up have concluded. and it would have to be all down hill from there in 2010
maybe a target time zone of mid november thru december to jan 2010. target 1200 s+p 500
The next moment to 'see' if this is what is playing out will be when the s+p 500 drops back to the 1020 area,holds there, does it again, holds at 1000 ,creating at least a few double bottoms,in the next 6 weeks. especially the time period november 3 to november 17 area.
it would make for a very optimistic christmas. If the markets are being 'engineered' I could see this happening. - 5:47 PM
I don't know to what extent the markets are being engineered. The dollar certainly is. The Fed. conducted credit default swaps to engineer a rally in the dollar recently. Gold is also manipulated by central banks lending out their supplies to major banks and then extending the leases when it suits them. Stocks respond to the price of gold and the dollar, so at the git-go, yes, the market is manipulated even during ordinary times. Unfortunately, these are extraordinary times. My guess is we have no clue to what extremes the acolytes of Keynes will go.
Also, the volume in stocks is so thin right now, there is plenty of potential for manipulation. This rally has so few leaders, only a handful of stocks (Citi, AIG, etc.) have accounted for up to 40% of the NYSE trading recently. Even if there is nobody pulling the strings, that kind of pinch in volume just invites the the giant squids of finance to latch onto the face of America and manipulate the markets (GS et al).
My great fear has also been that the agony is prolonged and the pronounced leg down doesn't come. I hope you are wrong because that would be a worse case scenario. It was bad enough growing up in the age of disco and being told the world was going to end every day. I couldn't handle that again.
I don't believe in astrology but market tops and bottoms corresponding with the calendar is always interesting. However, I wouldn't jump to the conclusion it's related to the stars or the moon, because so much of market contributions and reporting are tied to monthly and annual periods. The Federal TSP is a case in point, with 13 million participants paying into their 401k every two weeks. Please elaborate on what you see. Are you saying the tops and bottoms over the last few months are tied to a monthly rhythm?
Smiddy - 6:44 PM
Oops, I meant to say the Fed engineered currency swaps, not CDOs. sry
Smiddy, thanks for addressing my points. I can see that we are basically 'on the same wavelength' in what we are seeing. however whatever way we come to see it. my own vision does include this peculiar 'indicator' of watching the calendar for the full moon and the new moon. you can always find it by looking at an ephemeris . (www.khaldea.com)
I read a blog post or two here that pertains to the (Nobel Prize nominee?!) J.Taylor's work ...involving the research he did to show that markets move in relation to ....gravitational energy... ok, I can relate to that idea. it must be about the moon... like the way it affects tides, and psychological emotions..(many studies have been done and stats from mental hospitals and police departments confirm the effects the full moon has on people. it's well know in government and universities this effect. a major study was done in the 90's about this issue. it confirmed that the moon cycles, especially the full moon, does affect the emotions of people, and in a market environment, where 'emotion' plays a big part in 'investor sentiment' ,public mood, etc... it does have an effect on the markets and its participants.
the university study is worth reading.
there are some specific details about it that are especially pertinemt.
Anyway, the bottom line, is that I have been open minded about ....watching the full moon time and new moon time, to see if it can be used an an indicator, like the other indicators, CCI, RSI, etc....elliot waves, etc. and so far, I am seeing that it does look to be a very good 'timing' indicator.
Having said that....I also agree with the point you made about the Fed TSP, monthly reports, etc. the news releases are important.
but when you put all these indicators together , I think it can give us some 'vision' of potential that is tradable.
the next tradable timing point , for me , is october 17/21 area...IF the S+P 500 is hitting big resistance at the 1060 area,with a double or triple top, etc, and other indicators are telling....I will be looking for the trigger to sell short the market for the start of sub wave 3 down....my target is (s+p 500) the 950 area. between the june top and july bottom. (925 area)(950)
BUT ..... the place along the way... for the government to 'engineer a stick save'....would be 1020. the recent bottom. (1020-1000 area)....so it has to be watched daily.
well, thats what I'm looking at....while I wait. - 9:02 PM
Thanks T, I never studied that subject but I'll take a look at it. I've got plenty of spare time since the open today.
I covered this morning when it blew through 1050. You can't fight a falling dollar. Each time the rally resumes, the euphoria grows. A bull would point out that they successfully reinflated the bubble before, so why not now? There's logic in that position, but I think it's a whole different economic situation now and we're perched on the edge of a cliff.
Smiddy - 8:43 AM
I agree. One place you can find that university study that was done....is go to Elite Trader web site. and search for the thread that is called....'trading the moon'. Its an older post from a few years ago. you might also locate it by searching the posts of username ...Yoohoo.... he uis a master trader,I learned alot from in his posts.
In that thread is a link to the university study.
The most significant point I got out of it was their evidence that the Full moon energy has the Most effect on emerging markets,small cap businesses, smaller systems.smaller economies of scale.
and that makes sense, because the smallness, smaller volume, etc, and localized nature,makes the public emotion around the market , or company, that much more emotionally invested, makes sense. like the way a family business has more emotion vested in it. smaller, emerging economies are more personal...so the moon has a stronger influence. I surmise (the study didnt address it) that for this reason, the Forex market would also be one that is more influenced by the timing of the moon cycles.


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Enterprise Mobility: Apple iPad 2 Materials Cost $326.60 for 32GB ATandT 3G Tablet
With the iPad 2, Apple has managed to keep its costs "virtually the same" as with the original iPad, IHS iSuppli reported following a teardown of the 32GB version of the tablet with 3G connectivity. The AT&T model, IHS iSuppli found, carries a BOM (bill of materials) totaling $326.60 before manufacturing costs, while the Verizon Wireless model totals $323.25. By comparison, the 32GB version of the original was $320. The priciest item on the iPad 2's bill, by far, is its touch-screen and display, which the analyst firm says is partly due to the "manufacturing challenges" it presents. Other notable components of the iPad 2which was launched March 11include its GSM/HSPA (High-Speed Packet Access) Intel chipset, which is identical to the iPhone 4's; its speedyand priceyA5 processor, which costs 75 percent more than the proprietary A4 in the first iPad; and the battery, again is improved but also is pricier, which along with Apple's special battery-management circuitry, says IHS iSuppli, provides an "exceptional result."


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Looking for a Japanese Usability Testing Partner
9 Mar 2009 - 8:04am
1 reply
973 reads
Hey guys,
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How do you coax the most thoughtful and disruptive work out of creative teams? You inform them in original ways. Paint a vivid narrative of the target audience. Connect them to all the ways the message can impact customers.
And never, ever sacrifice relevant for irreverent.
There are so many ways to influence an audience with creative and content. Here are just some of the services we currently deliver for our clients.
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Today's media landscape gets more complex by the minute. It requires a balanced understanding across not only digital and traditional channels, but social, mobile and new offerings as well. Our team of full-service media experts build highly impactful B2B and consumer media plans based on real-time performance reporting and analytics. The result? You get more return for every media dollar spent.
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In today's metrics-driven world, data is more important—and more abundant—than ever. But do you have the right data to meet the needs of your sales and marketing campaigns? Can you:
It is not the quantity—but the quality—of data that is important. With high quality data that meets the specific needs of your organization's go-to-market strategy, you can successfully deliver on all of these requirements, reaping the benefits that will enable you to overtake your competitors. You'll be able to:
CatapultWorks has solutions that will help you turn your sales and marketing systems into the strategic assets they were meant to be. We've helped hundreds of companies:
Take advantage of our standard service offerings, or have us partner with you on an ongoing basis to manage your data and operational needs.
It's hard to be successful if you begin your sales and marketing campaigns with dirty data. Too often, great intentions falter due to issues such as duplicates, wrong names, wrong email and mailing addresses, false companies and incorrect titles. These data challenges will hinder your ability to target the right message to the right contact at the right time. So your campaign response rates will decrease and your opt-outs will increase. In addition, your reporting will be flawed, your campaign ROI will be minimal and the fees associated with your systems will continue to increase. And most importantly, you won't be able to generate the demand needed to achieve your revenue goals.
CatapultWorks can help you assess the quality of your sales and marketing data, identify your data quality challenge areas, work with you to clean the data and develop ongoing data quality solutions. We've worked on hundreds of data quality engagements—across small businesses and large enterprises in virtually every industry. In fact, we've helped the leading sales and marketing technology vendors, including SFDC, Eloqua and Marketo get their data clean—and keep it clean. And we've helped their largest clients as well. So we know what works.
We've helped our clients get the most out of their sales and marketing data and have achieved the highest results by:
Our 40-point data quality assessment will provide a comprehensive audit of the data housed within your SFA, CRM and marketing automation platforms. Its detailed charts, graphs and analysis will show the extent of your data quality challenges, including:
The assessment will also contain recommendations for cleaning and augmenting the data. This will help you to overcome these data challenges, enabling you to meet your specific sales and marketing objectives.
Want to see a sample of this comprehensive assessment? Just click here to sign-up for a live demo.
Once the data quality challenges are uncovered through the assessment, we will work with you to clean-up the dirty data within your systems—through the usage of advanced de-duplication, hygiene, and data standardization processes. Our unique, proprietary algorithms enable us to:
And, since we have years of experience with all of the major SFA, CRM and marketing automation platforms, including SFDC, Eloqua, Marketo, Silverpop and Aprimo, we can make the approved updates to your data directly to your systems. So your users won't have downtime away from these critical enterprise applications.
As organizations grow organically and through acquisitions, multiple databases, SFA, CRM and marketing automation tools are often used by individual groups and departments throughout the enterprise to manage sales and marketing data. In order to gain efficient economies of scale, consideration should be given to consolidating or even migrating these systems to a more sophisticated and comprehensive platform.
Using our time-tested data quality assessment and cleansing processes, CatapultWorks can assist you in determining the duplication and extent of data across these various systems. We can then consolidate and integrate standardized data from all relevant sources into a single, or multi-level strategic asset, which will deliver on your sales and marketing objectives.
Increasingly, data is at the core of sales and marketing success. You need to have the right data, available at the right time—and in the right format—to meet the ever-increasing demands of today's sales and marketing environment. It is important that your data is properly captured, processed, stored and managed in order to ensure:
This requires significant up-front strategic planning, development of standardized operational processes, and diligent, ongoing governance to ensure compliance.
Learn more about CatapultWorks' data management by reading the case studies below. And when you are ready to get started, click here to speak with one of our data management consultants.
At CatapultWorks, we take both a top-down and a bottoms-up approach to data. We look at data from both a strategic perspective, as well as from a more granular, 1's and 0's approach. As we get a better understanding of your marketing and sales objectives, we will find out the necessary approach to satisfy your data capture, storage, quality and usage needs. And we will dig even deeper—to get to know your existing sales and marketing data, analyze your data systems and operational data processes. The result? A successful database marketing strategy that will meet your end goals.
Sales and marketing are highly dynamic disciplines with ever-changing needs and requirements. As a company grows, its go-to-market strategy will change. New accounts are added to the target list on a continuous basis. And new customer engagement models are introduced to the current mix.
These changes can affect the data, systems and processes that you have put in place. So it is important to have resources available to ensure that your data structures, flows and processes are enhanced and optimized as needs arise. CatapultWorks can help provide a solution—whether you have a custom application, or a leading marketing platform to manage your data and processes.
Sales and marketing databases are dynamic entities that continuously change as data is imported, processed, used and distributed within and across enterprise-wide systems. Ongoing management and monitoring of these databases are imperative to ensure:
CatapultWorks' team of experts can partner with you to develop and document your company's standard operating procedures (SOPs) relating to ongoing data management. This includes the following:
These SOPs are the backbone of successful data management, as they provide a guide for data governance and stewardship. CatapultWorks can train your team to utilize these standards to manage your data. Or, you can outsource the management and governance of your databases to our team of experts. Some of the processes that we manage include:
The success—or failure—of every sales and marketing program starts with the list. Sales and marketing can choose to use existing contact lists, buy, rent or even custom build the "perfect" role-based lists.
With over 10 years of experience across hundreds of demand generation projects, CatapultWorks has developed the know-how and the industry relationships with the leading data providers—in order to produce the best list at the lowest possible costs. We will work with you to determine the advantages and trade-offs of each list development approach (build vs. buy vs. enrich vs. rent).
Targeted list purchases
Custom, role-based list builds
House list augmentation and enrichment
CatapultWorks' comprehensive experience has determined it is often the case that a combination of build, buy and enrich is the most effective course of action to meet our clients' quality, volume, cost and time parameters. But we manage the entire process for you, so you don't have to manage multiple vendors and data providers. And the end result will be a high quality set of contacts that will increase the accuracy and efficacy of your sales and marketing programs.
CatapultWorks list development services can exponentially improve the results of your sales and marketing campaigns. To learn more, just click here to meet with one of our list development experts.
CatapultWorks can help your marketing team take advantage of marketing automation technologies by providing the strategic, technical, operational skills and best-practice knowledge needed to make them work in the most effective way. We can meet your company's specific needs to:
Learn more about CatapultWorks' marketing operations by reading the case studies below. And when you are ready to get started, click here to speak with one of our marketing operations specialists.
With years of hands-on experience, CatapultWorks successfully supports the leading cloud-based marketing automation and CRM platforms, including Eloqua, Marketo, Silverpop and SFDC. We will work with you to understand your specific go-to-market strategy to ensure that the technology works the way your business needs it to work. As your partner, we will confirm that your systems configuration and integration deliver:
The proper management of responses is imperative to getting the greatest return on your investment in your demand generation campaigns. Over 50% of responses are never followed up due to incomplete data, incorrect method of contact or incorrect distribution. Another portion of the responses are not yet ready to buy and should never have been distributed to the sales team for follow-up. To ensure that each response gets the right next action at the right time, CatapultWorks can assist you in developing and deploying your lead management strategy. Our management process includes:
We can help you facilitate the conversation between marketing and sales that is needed to gain consensus on your lead management strategy. Our proven methodology will enable you to easily and efficiently determine the most appropriate lead qualification parameters and follow up rules, as well as proper hand-offs to telemarketing, telesales, or sales. In addition, we can help you in the creation of lead nurturing strategies to handle those responders that are just not ready to buy. Our experts will partner with you to develop and deploy tactical, multi-channel campaigns that will assist in moving hand-raisers down the buying cycle.
CatapultWorks provides campaign development and execution services to some of the world's leading brands. We've driven millions of interactions, across multiple online and offline channels, which have generated significant volumes of demand for our clients. Our proven marketing operations methodology ensures that your campaigns are executed accurately and consistently—taking advantage of best practices and marketing automation functionality. Our experts can partner with you to develop and execute:
Intelligence is at the core of any good marketing strategy. That's why performance metrics and data analysis are key. The results serve to inform the best possible future tactics that will drive demand and revenue generation.
CatapultWorks partners with our clients to develop and deploy dashboards, in addition to reports, which measure and track the metrics that matter most to their specific business. With our data expertise, we can work from the inside-out to ensure that you have captured (or integrated) the right data to meet prospect goals—as well as analyze the data to provide strategic recommendations that will help you to drive your business forward. With CatapultWorks, you are ensured:
Some of the most prevalent—and costly—data quality challenges that impede upon the success of sales and marketing campaigns involve missing or inaccurate data. This includes the following:
The result? While you've already invested significant dollars to acquire the contacts in your sales and marketing databases, you're unable to capitalize on your investments. Or, you've just simply been unable to acquire the data for key contacts within your strategic segments.
CatapultWorks has helped hundreds of clients to optimize and enhance their data acquisition initiatives. Our data validation, enhancement and augmentation strategies include:
Time and time again, we have seen clients reap the benefits by partnering with CatapultWorks. We have successfully incorporated data enhancement and augmentation strategies to their demand generation initiatives and have delivered these results:
CatapultWorks data appending and enhancement solutions can optimize your data acquisition investments. Want to learn more? Just click here to meet with one of our data experts.
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Telemarketing or teleprospecting programs should ultimately be judged a success by one metric—Closed/Won revenue. This requires clear communications, defined roles and goals between Sales and Marketing teams, and closed-loop reporting. CatapultWorks' methodology combines best-in-class teleservices, exceptional data, and nurturing processes to deliver calculated, repeatable ROI for our clients.
The result is maximized ROI for customers.
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See how our Integrated
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Wednesday, November 10, 2004 :::
The Presurfer has discovered this amazing invention. Invest while you still can. Banana Guard ::: posted by dan at 4:12 PM :: [ link ] :: (4) comments
4 previous comments: I won't, because it is just too easy. I totally want a Passionate Purple one and I am not going to say what type of banana it will protect. (sorry, it's like being told not to push a giant red button) B* By , at 10:03 PM I hate it when banans get bruised. And I think the obvious sicko choice would be the Glow-in-the-Dark one... By lynne, at 11:04 PM I want the glow in the dark one for legitimate reasons... you know how hard it is to find your banana in a power outtage? By jen, at 12:03 AM The glow in the dark one would have to be placed under somesort of light source in order to glow, and then your bananna would be all warm. Gross. By Kristina, at 10:25 AM < Back to Blog |
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Hal Ferguson writes to express his displeasure with former President Bill Clinton visiting last week, Dr. Jeff Evans writes in support of the school bond issue and says that local residents have a great opportunity and a great responsibility, and Jane Fraser writes to inform people that there's help for those who stutter. (October 19, 2010, Page 4)
Sunday, April 19, 2015
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BRATTLEBORO The U.S. Environmental Protection Agency says one community in Vermont and two in Maine will receive technical assistance to pursue sustainable growth that encourages local economic development while safeguarding peoples health and the environment.
Brattleboro, along with Brunswick and Portland in Maine, are among 43 communities in 27 states across the country chosen to receive the assistance through the EPAs Blocks for Sustainable Communities program.
EPA staff and national experts will conduct one- or two-day workshops focusing on the specific sustainability goal each community chose in their initial application to EPA.
Some of the tools offered this year included projects called a Green Building Toolkit, Land Use Strategies to Protect Water Quality, and Using Smart Growth to Produce Economic and Fiscal Health.MORE IN Vermont NewsMONTPELIER Gov. Full StoryTwo Vermont senators are trying to resurrect a plan to increase Medicaid reimbursement rates for... Full StoryMONTPELIER A new study looks at the use of paraprofessionals in the states public schools, and... Full Story -
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14 Global Climate Change: A Glance in the Rearview
Just how far back does the geologic record take us in understanding Earths
past climate?
Matthew Huber
20 Lake Titicaca: An Archive of
South American Paleoclimate
Researchers are drilling sediments in Lake Titicaca in southeastern Peru to
understand climate changes on small time scales.
Paul Baker et al.
and Views
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News Notes 12 Political
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RV Appliances | RV Furnaces | Next | Next Image |
RV Appliances | USED SUBURBAN RV/MOTORHOME 16,600 BTU FURNACE MODEL: SF-20 *OUT OF STOCK*
SuburbanRV/Motorhome Furnace Available for local pick-up at a discounted price. Please call Visone Auto Mart for details: 606-843-9889. Many Atwood & Suburban furnaces in stock. Please see other listings. Unit has been tested and is fully functionable. Condition may vary. Please note: All used parts are sold as-is with no refunds!
Condition: Used
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"Heroic Blues"
Released on Cockaigne , July 2002.
all songs written by David Graney. Copyright Control
anchors aweigh in the beginning it was so hard to breathe so hard to see so hard to find some space like the air was earth packed tight so many people all around and above and below anchors aweigh then there was a time of great confusion in the world I drifted, free from the earths drag there were no borders there was no night or day there was no end in sight there was only the vast and weightless pull of the time around and ahead anchors aweigh anchors aweigh anchors aweigh there was that song of yours somethin' about your eyes watchin' someone well now it's so hard to hear now those eyes are closed the streets of london the streets of perth dog eared pages in a library book collected on the fly shovin' off from the shoreline anchors aweigh all the people there were strangers to me again anchors aweigh anchors aweigh anchors aweigh
son of maggie mae she threw my old man out the front door one cold , windswept night she threw his clothes down from the first floor window he said he was too young to stay he was gonna move off to LA or somewhere she said, "you'll always be haunted by these windswept ,cobblestone streets you'll never get over me no matter how far you go what kind of brandy you drink" I don't remember all my fathers faces I lost track of all the city rooms we rented there was a pool cue in the corner in a grand old case a tartan scarf and a macintosh by the front door for a while she left my pram outside the front door to soak up the sun for a while two hoboes took me for a while left me in a supermarket aisle she brought me into her world in her wild way she was never a girl people whispered a famous name an old folk song goes all over the place every foot step was illuminated they say she had her wild times long before and long after I arrived the way I knew her she was so quiet we were like balls of mercury forever breaking forever the same he ran away she ran away I ran away money comes from somewhere every now and again an old folk song goes all over the place a poor boy sits in a palace hung with portraits of Jack the Ripper and the Prince of Wales
Leavin the Mount theres a show on up the road someone's puttin on a keg your shoes are made of retread tyres you drive an immaculate Morris Minor the guy you like has got greasy hair and a bad leg he dropped his bike on a party night you only see each other with a mob around he drinks until he gets carried home green ginger wine and buddah sticks chillums,shotguns,panel vans your high waisted jeans are too tight whats that song you like? "La Grange........" some people you know packed up and flew north that'd be somethin to just get in the van and go you know maybe as soon as his leg comes good the skin graft and the bone as soon as the physio says its cool and the insurance cheque comes through
clingin' to the coast clingin' to the coast holdin' to the inner city who knows what horrors lie in the west the beach the sand the coast the bay the coffee the tables on the footpath the bars the faces the little shops the markets the lovely village the vibe you read about walkin' everywhere your reflection in the window the excellent windows funny chairs old cars out west they have factories out west there is no water out west it is dry mornin' sun in your eye afternoon sun in your eye clingin' to the east holdin' to the inner city who knows what horrors lie in the west don't go no further don't go inside there is no water you might never come back they got hired guns they got hangin judges they got lawless streets and roaming savage tribes
I will always hate you Sometimes I'm sittin about with my pals shootin' the breeze layin' backnlaughin' drinkin' wine then ,out of nowhere you spring into my mind like a ghost touchin' my shoulder like a chill comin' over the room I will always hate you you got the power I dont know how I dont know when you made the move you got the mozz on me I will always hate you I know it's stupid I shouldn't be so weak I must be vigilant I must be strong I must remember there is somethin' I have to do there is a certain time and place that I really have to make I will always hate you
don't mess with the blood we've got such a lot of unfinished business so many things have happened so much time has passed you start to say somethin' you think "not now, it's not the time!" the time is never gonna be right. it's the blood don't mess with the blood we see each other so rarely you come up with some bullshit you fling it so freely I should've thrown it back long ago I guess you think I like it I took it from you once, I must it's the blood don't mess with the blood it'll take a lot to turn this baby around I don't have the time do I have the energy? what for? what place are we gonna get back to now? what shape? at this late hour! don't mess with the blood it's the blood don't mess with the blood
Heroic Blues I'm standin in a bar singin my songs theres six people hangin around they've got nowhere else to go I'm a hero, thats what I do no one buys my records no one knows my old songs I've played here before there were so many people I'm a hero , thats what I do looked at from another direction, this could seem pretty sad tragic even I gotta pull somethin out of this moment that woman at the back of the room shes travelled so far I'm a hero , thats what I do I'm livin out the other side of a dream I'm comin down I'm flattening out I'm slowly makin my way back to the big room I'm a hero , thats what I do I've seen this place before I've been around three times there must be somethin I could do am I in colour? or is it black and white from now on? am I losing? am I winning? how long have I been playing? when did it become a game? I'm a hero , thats what I do you know they can't breathe this atmosphere people off the street can't live at this speed I'm ridin over the scene I'm all over the room I'm a hero , thats what I do I got blues heroic blues I don't just lose I make heroic blues its a star vehicle and I'm the writer and I'm the director and I'm the player I'm editing in camera I got blues I got blues heroic blues my life has a life of its own my dreams have dreams of their own my blues have blues of their own I got blues heroic blues
I don't know anything I didn't know much but what I knew I really knew upside , over, back to front my mind was like a torch light in a pitch black room but that light was hard, so hard I could even see through it I could see through my world to the other side if I'd've met you then you wouldn't be around now I'd've slayed you where you stood I knew everything now, I don't have the juice I don't have the concentration I don't have the power I don't know anythin'! it's like I'm standin' in a floodlit stadium I'm at the centre square I know the names of the streets outside and where they go I know the last time I went to the end of those streets I know I'll never get to the end again in a long while I know I don't know anythin'! I don't know anythin'! I don't know anythin'! I don't know anythin'! I don't know anythin'!
eye o' the vibe the vibe was not with me the movin' finger havin' been chewed moved across the page I just know it ain't like it was every step was illuminated everybody knew what was gonna happen next I just know I am alone there weren't a thing that I could do walking along a dirt road there weren't no end in sight the stones cut into my bare feet I shiver and stand still no one knows where I am the wind blows the vibe was not with me I was deep in alien waters I over extended myself the crowd was with me woke up deep in debt to some rough bastards they don't care about the game I'm playin' they just want their wedge I just cant get ahead the vibe was not with me now I feel the soft grassy earth bounce under my feet I hear the whispers of sweet encouragement in my ear the world I knew is gone yeah I know my way back,baby it is time for me to keep my gums flappin I know how to live in a new way the vibe was not with me the swells had glassed out the sets were ages in between I'd been a fool I'd been so soft I should've stayed a little behind the play sat with my back to the door and watched the sky the vibe is with me yeah the vibe is with me
are we goin too fast for love? how do we find each other? how do we meet? how do we tell the difference? who is what and what is not? that special person? what's so special? are we goin' too fast for love? so many films have been made so many scenes have been played out do we meet in a bar? or look across the room at a party? is it through a friend of yours or a friend of mine? does it matter that weve danced before? with other people and we lost tried too hard and drove them away are we goin' too fast for love? will we be walkin' across a parkin' lot outside a supermarket that's closed? will we get to talkin'? wouldn't you be scared? how do we get to cross all this space between us? how do we make the leap? do we get drunk or take some drugs so if things turn out not so good we can say we weren't ourselves it was all a silly mistake are we goin' too fast for love?
a short bio of Clare and David
Lyrics to "kiss tomorrow goodbye".
Lyrics to the first album, "the Dave Graney Show''.


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Hi all,
I have three sqaure boards,the surface of the first contaning 5 sq feet more than second,and the second containing 5 sq. feet more than the third.Can you find the exact measurement for the sides of the boards?
Hi golchhamohit;
Is there anymore to the problem because I am getting multiple solutions?
In mathematics, you don't understand things. You just get used to them.
I agree with you regarding the satisfaction and importance of actually computing some numbers. I can't tell you how often I see time and money wasted because someone didn't bother to run the numbers.
Hi golchhamohit,
I can only get formulas for their relationships, not a numerical solution without more info as bobbym said.
Side lengths as follows:-
In descending order of board size:
In ascending order of board size:
Any value of x will give the 5 square feet differences between the boards' surface areas as per the puzzle wording.
Last edited by phrontister (2013-06-11 13:08:16)
"The good news about computers is that they do what you tell them to do. The bad news is that they do what you tell them to do." - Ted Nelson
Pages: 1


text:
A Simple and Robust Adaptive Controller for Detuning Correction in Field-Oriented Induction Machines
- file_1.pdf (798.9Kb PDF)
- Author(s)
- Publisher
- Citation
- Moreira, J.C., Hung, K.T., Lipo, T.A., & Lorenz, R.D. (1992). A Simple And Robust Adaptive Controller For Detuning Correction In Field Oriented Induction Machines. Ieee Transactions On Industry Applications, 28(6), 1359-1366.
- Date
- 1992
- Part of
- http://www.ieee.org/; http://ieeexplore.ieee.org/servlet/opac?punumber=28
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- This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.
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