text:
US 5461140 A Abstract Bioerodible ortho ester polymers useful for preparing solid form bioerodible pharmaceutical compositions such as pellets, capsules, suppositories and the like are provided. A novel synthetic method for preparing the polymers is provided as well as is a novel triol reactant. Synthesis involves a one-step reaction between a monomeric ortho ester and a triol. The pharmaceutical compositions of the invention are useful for the controlled release of therapeutic agents, and may be administered for a variety of purposes.
Claims(28) 1. A method for preparing a bioerodible polymer comprising:
reacting a monomeric ortho ester having the general formula ##STR11## wherein R is hydrogen or alkyl of 1 to 10 carbon atoms and R' is lower alkyl with a triol having the general formula ##STR12## wherein n is 1 to 5 carbon atoms, to form a rigid, bioerodible ortho ester polymer containing mer units of the structure ##STR13## 2. A compound of the formula ##STR14## wherein n is an integer in the range of 1 to 5 inclusive.
3. A composition comprising a polymer comprising mer units of the chemical formula ##STR15## wherein R is hydrogen or (C1 -C10)alkyl, and n is 1 to 5; or co-polymers thereof or mixtures thereof.
4. The polymer of claim 3, having a molecular weight of at least about 5,000, as determined by gel permeation chromatography.
5. The polymer of claim 3, having a molecular weight of at least about 20,000, as determined by gel permeation chromatography.
6. The polymer of claim 3, having a molecular weight of at least about 50,000, as determined by gel permeation chromatography.
7. The polymer of claim 3, wherein n is 1.
8. The polymer of claim 3, wherein R is selected from the group consisting of CH3, CH2 CH3 and CH2 CH2 CH3.
9. The polymer of claim 3, wherein R is selected from the group consisting of CH2 CH2 CH2 CH3, CH2 CH2 CH2 CH2 CH3 and CH2 CH2 CH2 CH2 CH2 CH3.
10. The polymer of claim 3, being a copolymer.
11. A bioerodible composition, comprising the composition of claim 3; and an excipient.
12. The bioerodible composition of claim 11, wherein the excipient is selected from the group consisting of acidic and basic excipients.
13. The bioerodible composition of claim 11, further comprising an agent selected from the group consisting of colorants, diluents, odorants, carriers, excipients, stabilizers and skin permeation enhancers.
14. A solid, controlled release pharmaceutical composition comprising a therapeutic agent dispersed in the bioerodible composition of claim 11.
15. The solid, controlled release composition of claim 14, in the form of a suppository, pellet or capsule.
16. The solid, controlled release composition of claim 14, wherein the therapeutic agent is present in an amount of about 0.001 to 70wt. % of the composition.
17. The solid, controlled release composition of claim 14, wherein the therapeutic agent is selected from the group consisting of anti-infective, analgesic, antihelminthic, anti-arthritic, anti-asthmatic, anti-convulsant, anti-depressant, anti-diabetic, anti-diarrheal, anti-histamine, anti-inflammatory, anti-migraine, anti-nauseant, antineoplastic, anti-parkinsonism, anti-pruritic, anti-psychotic, anti-pyretic, anti-spasmodic, anti-cholinergic, sympathomimetic, cardiovascular, anti-hypertensive, diuretic, and vasodilator agents, xanthine derivatives, central nervous system stimulants, cough and cold preparations, hormones, hypnotics, immunosuppressives, muscle relaxants, parasympatholytics, psychostimulants, sedatives, and tranquilizers.
18. The solid, slow release composition of claim 13, wherein the therapeutic agent is selected from the group consisting of steroid, anti-hypertensive, anti-allergic and thyroid affecting agents.
19. A controlled release method of delivering a pharmaceutical agent, comprising
administering to a subject the solid pharmaceutical composition of claim 14; and allowing the composition to release, in a controlled manner, an effective amount of the pharmaceutical agent while the polymer is bioeroded and physiologically eliminated by the subject. 20. The controlled release method of claim 19, wherein the solid composition is administered subcutaneously, intramuscularly or enterically.
21. The controlled release method of claim 19, wherein the solid composition is administered locally.
22. The controlled release method of claim 21, wherein the local admininstration is conducted by implantation or insertion of the solid composition proximate to a desired target tissue.
23. A method for preparing a bioerodible polymer, comprising contacting at least one monomeric ortho ester of the chemical formula ##STR16## wherein R is hydrogen or (C1 -C10)alkyl, and R' is (C1 -C5)alkyl, with at least one triol of the chemical formula ##STR17## wherein n is 1 to 5, under conditions effective to form a bioerodible ortho ester polymer comprising mer units of the chemical formula ##STR18##
24. The method of claim 23, wherein the number of mer units in the polymer is about 2 to 1000.
25. The method of claim 24, wherein the number of mer units in the polymer is about 2 to 200.
26. The method of claim 25, wherein the number of mer units in the polymer is about 5 to 200.
27. The method of claim 23, wherein
the monomeric ortho ester is reacted with more than one triol; and the bioerodible ortho ester polymer is a co-polymer. 28. A bioerodible polymer of the chemical formula ##STR19## wherein R is hydrogen, and n is 1 to 5; or co-polymers thereof or mixtures thereof, prepared by the method of claim 23.
Description This application is a continuation of U.S. application Ser. No. 07/877,847 filed on Apr. 30, 1992 now abandoned. The present invention is in the field of polymer chemistry and drug delivery. It concerns certain ortho ester polymers and methods for their preparation. These materials are bioerodible polymers, i.e., polymers containing hydrolytically labile linkages which undergo cleavage at physiologic conditions. These bioerodible polymers are useful for the controlled release of therapeutic agents. More specifically, the invention relates to solid drug dosage forms such as bioerodible pellets, capsules, suppositories and the like formulated with bioerodible polymers, and to the use of these solid bioerodible dosage forms in the treatment of disease conditions. Bioerodible polymers used to control the release of therapeutic agents physically dispersed in the polymer matrix have been described in a variety of contexts. One matrix which has been successful is a family of poly(ortho esters). These materials contain the pH-sensitive ortho ester linkage in their polymer backbone. Such polymers are described, for example, in U.S. Pat. No. 4,304,767 to Heller et al. Because the ortho ester linkages within these polymers are relatively stable at neutral pH, and hydrolyze progressively faster with the decreasing pH of the surrounding medium, the rate of erosion of the polymer can be manipulated within a very wide range by incorporating various levels and strengths of acidic excipients into the polymer matrix. The method of preparing polymers according to the aforementioned patent comprises the addition of polyols to diketene acetals as shown in Scheme 1. ##STR1## Using this scheme, almost any diketene acetal and any diol can be used, and the synthetic method is thus extremely versatile. Polymers synthesized by this method are, however, not optimal for preparing soft or amorphous drug dosage forms such as bioerodible ointments, creams or gels due to the relatively rigid pentaerythritol segment in the polymer backbone. Polymers and the method of preparing polymers for use in soft drug dosage forms are described in U.S. Pat. No. 5,030,457 to Ng et al. The method described in this patent involves reacting a monomeric ortho ester with a triol to form a polymer. The polymers synthesized as described in U.S. Pat. No. 5,030,457 have the desirable properties of being able to undergo bioerosion and of being less rigid and more flexible and conforming than prior ortho ester polymers. Polymers synthesized by this method are, however, not optimal for preparing solid drug dosage forms. There is thus a need in the art for a bioerodible composition which has a molecular structure of sufficient rigidity to enable its use as a bioerodible matrix in solid dosage forms such as pellets, capsules, suppositories or the like. An ideal material would enable the local or systemic delivery of an effective dose level of pharmaceutical agent from a subcutaneous pellet or the like at a desired rate for a period of time dictated only by clinical considerations and not by limitations of the solid dosage formulation. The ability to achieve this is particularly important with agents which when administered in an uncontrolled manner can produce serious side effects. The present invention provides bioerodible pellets, capsules, suppositories, etc., from which the release rate of the drug to be delivered--as well as the desired time period for drug delivery--can be carefully controlled. It provides materials which bioerode to small, water-soluble molecules that leave no residues in the tissue of the patient undergoing treatment. The invention thus enables improved treatment of a variety of disease states by the controlled delivery of drugs over prolonged periods of time. It is accordingly a primary object of the present invention to address the aforementioned needs in the art, and to provide bioerodible compositions in solid dosage form for the controlled release of therapeutic agents. It is another object of the invention to provide such bioerodible compositions in the form of bioerodible pellets, capsules, suppositories or the like. It is still another object of the invention to provide a novel method of synthesizing certain bioerodible ortho ester polymers useful for such compositions. It is yet a further object of the invention to provide certain novel bioerodible ortho ester polymers having the structure ##STR2## wherein R is hydrogen or alkyl and n is an integer in the range of 1 to 5 inclusive. It is a further object of the invention to provide a novel triol of the following structure: ##STR3## wherein n is as above. It is still a further object of the invention to provide ortho ester copolymers prepared by reacting a mixture of such triols with a monomeric ortho ester as will be described below. Additional objects, advantages and novel features of the invention will be set forth in part in the description which follows, and in part will become apparent to those skilled in the art upon examination of the following, or may be learned by practice of the invention. These objects are achieved by the present invention. In accord with this invention, a method is provided for synthesizing a bioerodible ortho ester polymer. This method involves: reacting a monomeric ortho ester having the general formula ##STR4## wherein R is as defined above and the R' are independently selected from lower alkyls, with a triol as shown above. This reaction forms an ortho ester polymer containing a mer unit having the following general formula (I) ##STR5## wherein R and n are as just described. A. Definitions Before the present invention is disclosed and described in detail, it is to be understood that this invention is not limited to specific therapeutic agents, dosage forms, or the like, as such components may, of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended as limiting. It must be noted that, as used in the specification and the appended claims, the singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. Thus, for example, reference to "a polymer" includes mixtures of polymers, reference to "a therapeutic agent" includes mixtures of therapeutic agents, and the like. The term "mer" is used to mean the structurally recurring units or monomer units of the ortho ester polymers provided by the present invention. The mer units of any given polymer may be the same or different; when different, they may be arranged in block or random fashion. When all the mer units of a polymer are the same, the polymer is called a homopolymer. When there are 2 or more mer units in a polymer, the polymer is called a copolymer. The present invention involves both homopolymers and copolymers. The term "bioerodible" as used herein to describe the polymers of the present invention is synonymous with the term of art "biodegradable." These terms denote the property of a body of solid gel polymer to undergo degradation, erosion and solubilization as a result of hydrolysis of labile linkages at the physiologic conditions of use. The terms "therapeutic agent" or "drug" are used interchangeably to mean a compound or composition of matter which, when administered to an organism (human or animal) induces a desired pharmacologic and/or physiologic effect by local and/or systemic action. In general, the terms include the therapeutic or prophylactic agents in all major therapeutic/prophylactic areas of medicine. The term "effective amount" as used herein intends that quantity of a therapeutic agent that, when administered to a patient, is required to provide the desired or intended beneficial effect without intolerable side effects, such as toxicity. When used in the context of controlled or prolonged delivery of drug, the term can include a temporal aspect--noting that the rate of administration gives the desired effect without intolerable side effects. The term "alkyl" is intended to mean linear, branched or cyclic alkyl moieties having 1 to 10 carbon atoms, inclusive. "Lower alkyl intends an alkyl group of 1 to 5, more typically 1 to 3, carbon atoms. B. Synthetic Method In the synthesis aspect of the present invention, a method is provided for synthesizing certain bioerodible ortho ester polymers. The synthesis is a simple, straightforward reaction which may be accomplished in one step in a single reaction vessel. The synthesis involves the reaction of a monomeric ortho ester having the general formula ##STR6## wherein R is a hydrogen or an alkyl of 1 to 10 carbon atoms and the R' are independently selected from lower alkyl, with a triol having the general formula ##STR7## wherein n is an integer in the range of 1 to 5 inclusive, preferably 1 to 3. The reaction is carried out to form an ortho ester polymer which comprises mer units of the structure (I) ##STR8## In preferred embodiments, the R moiety of the monomeric ortho ester reactant is a lower alkyl, the R' moieties are the same and are either methyl or ethyl. The synthesis of the ortho ester polymer from the monomeric other ester and triol is carried out either neat or, preferably, in an aprotic solvent such as tetrahydrofuran (THF), cyclohexane, ethylene glycol dimethyl ether (glyme), diglyme, cymene, cumene, chlorinated hydrocarbons, or the like. Typical concentrations of the two reactants can range from essentially 100% (neat) down through about 10% by weight or lower, when solvent is used. In either case, care must be taken to maintain anhydrous conditions. The reaction can be carried out at reflux and thus, depending upon the solvent, at temperatures in the range of about 50�-150� C., preferably about 50�-90� C. The approximate molar ratio of reactants is set at about 1:1 if it is desired to maximize the molecular weight of the polymer, but can be varied if a lower molecular weight polymer is desired. It is typically preferred to carry out the reaction in the presence of an acid catalyst, although in cases where the reactants are acidic, a catalyst is unnecessary. Examples of suitable acid catalysts include p-toluenesulfonic acid and methanesulfonic acid. The amount of acid catalyst can range from 0% (based on its optional presence) to about 1% molar (based on the amount of triol present). The two reactants may be readily synthesized using conventional techniques, or they may be obtained commercially, e.g., from the Aldrich Chemical Company, Milwaukee, Wis. Triols wherein n is greater then 1 may be prepared by reacting the salt ##STR9## (wherein X+ is a monovalent cation such as Na+) with an alcohol HO--(CH2)n-1 --Y where n is as defined earlier and Y is a leaving group. Ortho ester copolymer may be prepared by using an admixture of triols rather than a single triol, e.g.., using two or more triols differing with respect to the integer "n". C. Novel Polymers The novel ortho ester polymers provided by the present invention contain recurring mer units represented by Formula (I) ##STR10## wherein R is hydrogen or an alkyl of 1 to 10 carbon atoms, preferably a linear alkyl, more preferably a linear alkyl of 1 to 6 carbon atoms, and n is 1 to 10, preferably 1 to 5, more preferably 1 to 3. Typically, although not necessarily, the polymers have molecular weights of at least about 5,000, more preferably at least about 20,000, and most preferably at least about 50,000, and the number of repeating mer units in the polymer will normally be in the range of 2 to 1000, preferably 2 to 200, and most preferably 5 to 200. These polymers have the desirable properties of being able to undergo bioerosion and of being more rigid and less flexible and conforming than prior ortho ester polymers. D. Pharmaceutical Compositions The pharmaceutical compositions of this invention comprise a selected therapeutic agent or number of agents dispersed in a novel bioerodible ortho ester polymer as described in the preceding section. While the preferred pharmaceutical compositions of the invention are injectable bioerodible pellets and similar solid dosage forms adapted for the local or systemic administration of therapeutic agents, other compositional forms (e.g., capsules, suppositories and more rigid transdermal forms) and modes of administration (e.g., transdermal) are within the scope of the invention as well. The bioerodible dosage forms of the invention will typically include a pellet, capsule or suppository base comprising one or more of the bioerodible ortho ester polymers described herein and a selected therapeutic agent. The therapeutic agent, whether present as a liquid, a finely divided solid, or any other physical form, is dispersed in the pellet, capsule or suppository base. Typically, but optionally, the compositions include one or more other components, e.g., nontoxic auxiliary substances such as colorants, diluents, odorants, carriers, excipients, stabilizers or the like. The amount of active agent will be dependent upon the particular drug employed and condition being treated. Typically the amount of drug represents about 0.001% to about 70%, more typically about 0.001% to about 50%, most typically about 0.001% to about 20% by weight of the total composition being common. The quantity and type of ortho ester polymer incorporated into the pellet, capsule, suppository, etc., is variable. For a more rigid, less flexible composition, a higher molecular weight polymer is used. If a less rigid, more flexible composition is desired, a lower molecular weight polymer can be employed, i.e., one which is prepared with other than a 1:1 reactant ratio. The product may be based on only one polymer or it may comprise a mixture of polymers. While not essential for transdermal administration of many drugs, it may in some cases, with some drugs, be preferred that a skin permeation enhancer be coadministered therewith. Any number of the many skin permeation enhancers known in the art may be used. Examples of suitable enhancers include dimethylsulfoxide (DMSO), dimethylformamide (DMF), N,N-dimethylacetemide (DMA), desylmethylsulfoxide (C10 MSO), ethanol, eucalyptol, lecithin, and the 1-N-dodecylcyclazacycloheptan-2-ones (available under the trademark Azone� from the Nelson Research and Development Company, Irvine, Calif.). It is additionally preferred to incorporate an acidic excipient into the bioerodible dosage form in order to control the rate of polymer bioerosion. The ortho ester linkages of the bioerodible polymers are relatively stable at basic or neutral pH and are hydrolyzed at progressively increasing rates as the pH of the medium surrounding the polymer decreases. Thus, hydrolytic lability and the rate of erosion and drug release can be increased by incorporation of one or more acidic components. Preferred acidic excipients are aliphatic acids, typically present at 0-10 wt. %, more preferably 1-5 wt. %, of the bioerodible composition. Solid but water soluble aliphatic acids are generally favored. Examples of acidic excipients useful in conjunction with the present invention include adipic, citric, suberic, maleic and itaconic acids. Basic excipients may also be used to slow the rate of release. The variety of different therapeutic agents which can be used in conjunction with the bioerodible compositions of the invention is vast. In general, therapeutic agents which may be administered via the pharmaceutical compositions of the invention include, without limitation: antiinfectives such as antibiotics and antiviral agents; analgesics and analgesic combinations; anorexics; antihelminthics; antiarthritics; antiasthmatic agents; anticonvulsants; antidepressants; antidiabetic agents; antidiarrheals; antihistamines; antiinflammatory agents; antimigraine preparations; antinauseants; antineoplastics; antiparkinsonism drugs; antipruritics; antipsychotics; antipyretics; antispasmodics; anticholinergics; sympathomimetics; xanthine derivatives; cardiovascular preparations including calcium channel blockers and beta-blockers such as pindolol and antiarrythmics; antihypertensives; diuretics; vasodilators including general coronary, peripheral and cerebral; central nervous system stimulants; cough and cold preparations, including decongestants; hormones such as estradiol and other steroids, including corticosteroids; hypnotics; immunosuppressives; muscle relaxants; parasympatholytics; psychostimulants; sedatives; and tranquilizers. In preferred embodiments the therapeutic agents for administration in conjunction with the bioerodible polymers of the invention include steroid drugs, antihypertensive agents, anti-allergy medications, and thyroid-related drugs. Examples of steroid drugs useful herein include: progestogens such as norethindrone, norethindrone acetate, desogestrel, 3-keto desogestrel, gestadene and levo norgestrel; estrogens such as estradiol and its esters; corticosteroids such as cortisone, hydrocortisone and fluocinolone acetonide; and testosterone. Antihypertensive agents include, for example, reserpine, pindolol, timolol maleate, bufeniode, indoramin hydrochloride, minoxidil, sodium nitroprusside and captopril. Anti-allergy medications which may be administered using the dosage forms of the invention include chlorphenamine, dexamethasone, epinephrine and prednisolone. Thyroid medications include, for example, levothyroxine sodium, acetiromate, iodothyroglobulin, propylthiouracil, and the like. Other specific compounds within the aforementioned classes will be known to those skilled in the art or may be found, for example, in Korolkovas, Essentials of Medicinal Chemistry, 2nd Ed. (New York: Wiley-Interscience, 1988). E. Administration and Use Depending on dosage form, the pharmaceutical compositions of the preceding section may be administered in different ways, e.g., subcutaneously, intramuscularly, enterically, or the like. Preferred dosage forms are solid dosage forms which can be implanted or inserted proximate to the afflicted tissue for enhanced local delivery of drug (e.g., vaginal insertion of a suppository form), or in any selected appropriate location for the systemic delivery of drug (e.g., subcutaneous implantation of a pellet form) contained within a pellet, capsule or suppository. Parenteral delivery is preferred for administration of proteinaceous drugs such as growth factors, growth hormone, or the like. The ortho ester polymer, upon contact with body fluids including perspiration, saliva, lymph, blood or the like (depending upon the mode of administration), undergoes gradual bioerosion with concomitant gradual exposure of the dispersed drug to the afflicted tissue. This can result in prolonged delivery (over, say, 1 to 10,000 hours, preferably 2 to 1000 hours) of effective amounts (say, 0.0001 mg/kg/hour to 10 mg/kg/hour) of the drug. The application can be repeated as necessary depending on the subject being treated, the severity of the affliction, the judgment of the prescribing physician, and the like. The examples presented below are provided as a further guide to the practitioner of ordinary skill in the art, and are not to be construed as limiting the invention in any way. Under anhydrous conditions 0.3 moles of triethyl ortho propionate, 0.3 moles of 1,1,4-trihydroxymethyl cyclohexane and 20 mg of p-toluenesulfonic acid were weighed into a 500 ml round bottom flask and heated until the boiling point reached 81� C. After heating for an additional 4 hours, the solution was cooled to room temperature. Five drops of triethyl amine were added and the solvent was removed by evaporation. The residue was re-dissolved in 100 ml tetrahydrofuran and the solution was dropped into 2 l of methanol containing 1 ml of triethylamine. The precipitated polymer was collected by filtration and dried in a vacuum over. The polymer thus obtained had a M.W. of 51,000 as determined by GPC and a glass transition temperature (Tg) of 68� C. Following the procedure as presented in Example 1, 0.1 moles of triethyl valerate was reacted with 0.1 moles of 1,1,4-trihydroxy-methyl cyclohexane. The reaction gave a solid polymer having a Mw of 31,000 and Tg of 48.5�. Following the procedure described in Example 1, 0.1 moles of triethylorthoacetate was reacted with 0.1 moles of 1,1,4-trihydroxymethyl cyclohexane. The reaction yielded a polymer which precipitated out of the cyclohexane solution. The polymer was highly crystalline and was found to be insoluble in most organic solvents, such as methylene chloride, chloroform, diethylether tetrahydrofuran, ethyl acetate and acetone. It was found to be moderately soluble in dimethyl formamide and 1-methyl 2-pyrosolidinone. Following the procedure described in Example 1, 0.1 moles of triethylorthoacetate was reacted with 0.05 moles of 1,1,4-trihydroxymethyl cyclohexane and 0.05 moles of 1,2,6-trihydroxyhexane. The reaction yielded a polymer which was soluble in cyclohexane methylchloride, chloroform, diethylether, tetrahydrofuran and ethyl acetate. The polymer was found to have a M.W. of 22,000 as determined by GPC. Following the procedure described in Example 1, 0.1 moles of triethyl orthopropionate was reacted with 0.08 moles of 1,1,4-trihydorxymethyl cyclohexane and 0.02 moles of 1,2,6-trihydroxyhexane. The reaction yielded a polymer having a M.W. of 116,000 and glass transition temperature (Tg) of 56.7� C. This example illustrates the preparation of a bioerodible device capable of releasing drugs in sustained manner. 1.8 g of the polymer obtained by the reaction in example 5 (a polyorthopropionate) was dissolved in 5 ml of anhydrous tetrahydrofuran, and 0.2 g of 5-fluorouracil was added. Solvent was removed by evaporation. The mixture of polymer and drug was pressed into a 0.2 mm film on a curver press at 160� F. and discs of 7 mm diameter were cut and used for in vitro drug release study. The release study using pH 7.4 buffer at 37� C. showed that the discs released 5-fluorouracil linearly for a period of 7 days. Patent Citations
Non-Patent Citations
Referenced by
Legal Events
Rotate |


text:
Things to see and do - Baia Mare (Frauenbach/Nagybánya)
Leaving for Romania
Baia Mare (Frauenbach/Nagybánya) :
Unmissable tourist sites
Where to sleep?
Baia Mare (Frauenbach/Nagybánya) Hotel tips
Hotel Carpati from40 €
Book -
Hotel Diafan from39 €
Book -
Hotel Ambassador from29 €
Baia Mare (Frauenbach/Nagybánya) Travel guide
Baia Mare (Frauenbach/Nagybánya) : Michelin's recommendations
Gold and silver mines in the Maramures region brought wealth to this town, which has also developed its tourist infrastructure. Its historic centre has the fine Baroque-style Liberty Square, dominated by St Stephen's tower (1468). Baia Mare is proud of its five museums housing a variety of collections; note the museum of art (modern Romanian paintings), the Maramures regional museum (local history) and the museum of ethnography and folk art (devoted to artisanal crafts from the area).
Tourist attractions Baia Mare (Frauenbach/Nagybánya) : Things to see and do
Valleys of Maramures
RO - Baia Mare
It is impossible not to be impressed by this region distinguished by its bygone pastoral traditions. In the northwest of Romania, Maramures offers a splendid landscape of untamed forest and hillsides tilled by man, rich architectural heritage (notabl..
St Stephen's Tower
Str. Turnului RO - Baia Mare
Symbol and pride of the city, this fine Gothic tower was built between 1446 and 1468 on the orders of Iancu de Hunedoara and originally stood alongside the cathedral, another Gothic building, destroyed in a fire caused by lightning in 1769. From its ..
Maramures Regional Museum
Str. Monetãriei nr. 1-3 RO - Baia Mare
The museum has interesting Maramures Bronze Age objects (gold rings) and pottery in its archaeology collection (ground floor); upstairs, the focus is on the region's traditions, history and literature (furniture, tools...). The basement has an exhibi..
Hotels Baia Mare (Frauenbach/Nagybánya)
Hotel Rivulus
Strada Culturii nr. 3 RO - 430316 Baia Mare
Prix Prices from : 35 €
Hotel Rivulus offers rooms with balconies and free Wi-Fi, just a 10-minute walk from Baia Mare's historical centre. It includes a restaurant and a bar with summer terrace. The modern rooms at Rivulus Hotel all come with telephone, TV and minibar. Th..
Best Western Eurohotel
Bucharest Blvd., no.23 RO - 430251 Baia Mare
Prix Prices from : 39 €
Best Western Eurohotel, less than 2 km from the centre of Baia Mare, offers rooms with free Wi-Fi. It offers free access to the indoor pool, the sauna and the gym. All of the air-conditioned rooms at Eurohotel have cable TV, a minibar and a refriger..
Hotel Ambassador
Str.Moldovei 2 RO - 430265 Baia Mare
This 3-star hotel is centrally located in Baia Mare, a 10-minute drive from the train station and 9 km from the airport. It offers spacious rooms with free Wi-Fi, air conditioning. The city's popular shops, bars and restaurants on Bucharest Boulevar..

subset: commoncrawl


text:
Key things you need to know aboutDr. Wade III:
Dr. Wade III's Experience
Research training, expertise and qualifications
Dr. Wade III's Care Philosophy
Dr. Wade III's Specialties
Conditions Dr. Wade III Treats
- Adrenal Gland Cancer
- Anal and Rectal Cancer
- See all 50 conditions
More About Dr. Wade III's Background
Patient Satisfaction
Patients' feedback on their experience with Dr. Wade III
Likelihood of recommending Dr. Wade III to family and friends is 1.3 out of 5
See More Survey Results
8 Facts About Patient Satisfaction Surveys
Patient satisfaction surveys provide a standardized way of reporting about healthcare experiences. But there can be more than meets the eye when reviewing scores. Here's what you should know
Appointments & Offices
Check insurance plans, locations and make an appointment
Accepting new patients?
- Yes
- Virginia Cancer Institute-Mechanicsville Office
- 7501 Right Flank Rd Ste 600
- Mechanicsville, VA 23116
7 Tips to Prepare for Your Appointment
The key to a successful appointment is communication. To get the most out of your visit, prepare ahead of time so you can lead the conversation with your doctor. These 7 tips will get you ready


text:
No, I'm not embarrassed.
I'm not even on fb that's how much I hate sharing pics lol. I use email if I need to share. It's very personal nd I think normal how u feel I think he just felt different ppl react in different ways maybe he needed to feel supported by lots of them? Either way I'm sorry you had o go through such a scary surgery for your. Baby snd I pray he gets stronger evrryday sorry for. Y autocorrects. :/
the bad thing is what other people would do with a copy of that picture like make up a radiculous back story or something, I don't blame you for asking them to remove it.
Quoting imapepper:What's the difference in posting it on facebook or posting it on here? We are all complete strangers you are sharing it with.
I agree with you. My heart just drops when I see those pics of suffering infants/ people, and FB pages just asking people to 'like' them saying stupid things like 1 like = 1 prayer etc. most of those pictures are 'stolen' and created by people that has no relation to the person in the picture.. I would never want my pictures ending up like that.
That's silly. Taking a picture doesn't mean you also want to share it with 300,000 or so people. Not even pictures taken for commercial use let you do that. Even they have rules on how they can be used. Like everything else there are boundaries that we only let people we want, enter.
Whats wrong with you anyway... Have some compassion. A picture of one's baby covered in blood and tubes is not same as your bath picture. A parent may take any pic they want so they can show it / or not, when the kids grow up. But every picture certainly do not have to be shared.
Quoting Anonymous:
I'm a firm believer that if you don't want people to see the pic don't take it. Problem solved. If you don't want your baby on social media then watch them and ensure no photos are taken without that clear understanding. Personally it does not bother me to have pics of ds on facebook and I never took bath pics where his bits were uncovered. I really wish people would think this stuff through prior to having kids because I am so sick of the omg I'm gonna whine cause my kids pic is on fb posts. Duh. What did you think would happen?
my SO grandson had the same surgery. We, his family, wanted to know how everything was progressing. The mom posted pictures and updates for all of us. It was a great way to know how everything was going with the surgery and the recovery. I also feel the same way you do and pictures should not be shared. Friends and family should have kept that all private, but most of the time, it is unavoidable.
I have been in your situation. My son had surgery at 3 weeks old. his dad and i were the only two to see him after his surgery, he was on a ventalator and he looked awful :( we took pics that were for us and for him when he got old enough to understand, we shared pics of his journey on facebook, but no one has seen the ones after his surgery except his dad and i. i would be LIVID!!!!


text:
Pronunciation: médicinal
Added on: 2010-12-29
Listened: 9 times
Add categories to médicinal
Pronunciation in French [fr]
- Pronunciation by purplelunacy (Female from France)
0 votes
Could you do it better? different accent? Pronounce médicinal in French
Accents & languages on maps
- Random word: métaux de transition
Not satisfied?
Modify word:
· Add languages
· Add categories
Report word:
Is there anything wrong with this word?
Please report it here.


text:
Posted on October 11, 2010 at 8:46am 0 Comments 0 Favorites
Autism Learning Felt and Super Mommy To The Rescue have come together to host a Special Needs Blog Hop. With all the Blog Hops around just how many of them are dedicated to Special Needs? With
the blogosphere being really big we wanted to reach the ones that blog
about Special Needs. Whether it's autism, cerebral palsy, ADHD or
physically handicapped, your all welcome to…
Stacie, Id love to have you check out my blog Angels of Inspiration. Become a part of our growing family by becoming a follower and sharing your comments and thoughts in the comment section of our posts.
I think it would be awesome as well as inspiring to our readers to possibly do an interview with you on being a mommy of a special needs child. In my past posts youll find an interview I did with a gentleman with cerebal palsy Ive known him for 25 or so on years he now is a published poetry author.
Chech out my blog and we can go from there. Angels of Inspiration
We love a great holiday or weekend when we can really relax. This photo looks great, right? But, can you honestly ever relax?
© 2015 Created by Mom Bloggers Club.


text:
If the game freezes, just click inside it (games can get unresponsive if you click elsewhere on the page).
Yes |
No |
Timmy returns in a new Game Boy inspired metroidvania adventure! Explore a huge dungeon, collect hidden powerups and gain new skills to aid you in your quest! Can Timmy survive the dangerous dungeons and find the presumably huge treasure?
Arrow keys to move.
X to use and throw knives.


text:
Will the gray linen be restocked?
I was a little concerned about the light gray and the linen when I ordered as I have cats and a child. This material is very easy to clean and it does not snag easily and the color is perfect, beautiful, and I loooove it.
Add stylish seating to your room with this comfortable Uptown sofa. This modern piece features impeccable style with a tailored look.
- Details
- Shipping & Returns
- Reviews
The Uptown Modern Sofa has simple yet elegant lines. The easy-to-clean microfiber upholstery is stain-resistant and a neutral peat in color, making this the perfect piece for a growing family. Use this lovely sofa as the focal point of your contemporary living room. This piece's urban design makes it a great sofa for a young person's first apartment. This versatile piece has simple lines that work well with modern decor, and its warm cherry and peat styling have an organic feel that blends well in rustic-themed spaces.- Three (3) thick seat cushions
- Solid cushioned back
- Includes: One (1) sofa
- Materials: Solid Asian rubberwood frame
- Wood finish: Espresso or cherry
- Upholstery color: Grey linen, light brown microfiber, white linen, dark grey linen, mocha microfiber, sage microfiber, dark brown faux leather
- Upholstery fill: Foam
- Sofa dimensions: 34.5 inches high x 76.5 inches wide x 34 inches long
Assembly required.
Features | |
Color | Brown Green Grey White |
Style | Contemporary Modern Urban |
Material | Cherry Fabric Foam Linen Microfiber Rubberwood Wood |
Type | Sofa |
Finish | Cherry Wood |
Assembly | Assembly Required |
Furniture Frame Material | Wood |
Furniture Pattern | Solid |
Gallery Match | Yes |
Gallery Room | Hampshire Woods |
Dimensions | 76.5W x 34D x 34.5H |
Materials | Peat Microfiber Linen |
Model Number | 119913PT-3TL[SOFA] |
Customer Reviews
- Disclosures & Guidelines
- Filter By:
- Most Helpful
- Most Recent
Beautfiul! I was a little concerned about the light gray and the linen when I ordered as I have cats and a child. This material is very easy to clean and it does not snag easily and the color is perfect, beautiful, and I loooove it.
Read MoreErica C. Apr 22, 2015 - Helpful 0
- Not Helpful 0
- Flag as Inappropriate
brs mom ask me again later. bought now as it was the last one. have to paint the living room before unboxing and putting it together before making a real assessment.
Read MorePhyllis V. Apr 21, 2015 - Helpful 0
- Not Helpful 0
- Flag as Inappropriate
Fits the space well and does the job I bought this small sofa for our dining room redo. I wanted a banquette style with mix and match chairs and stools. I originally bought a different sofa that was way too short. This sofa is the perfect size. It was not my first choice, but for the price I thought it would work and it does. While the color is darker than pictured, I would have preferred a darker grey linen fabric. The couch itself is springy and firm. For pulling up to a long, farmhouse style dining table it works perfectly. It is deep enough to be comfortable, but not too deep and awkward to be used for dining. I would not buy this sofa as a primary sofa for couch viewing and lounging. It is too small and not deep or long enough to fit two comfortably or lay down completely flat. This is an accent sofa. I'm sure we will replace it in a few years, but that's ok since I wasn't expecting an heirloom quality piece at this price. It is perfect for small cozy spaces. Also, this couch comes flat packed and you have to assemble it. It's fairly easy, but still requires a bit of effort.
Read MoreStefanie S. Apr 21, 2015 - Helpful 0
- Not Helpful 0
- Flag as Inappropriate
Poorly made It was easy to put together and very cute. One the ends broke away from frame within a couple months.
Read Moreemiliarose Apr 21, 2015 - Helpful 0
- Not Helpful 0
- Flag as Inappropriate
Cindy K this looks great but is not a comfortable sofa. I use it for my staging company though so it was a great value for me
Read MoreCynthia K. Apr 21, 2015 - Helpful 0
- Not Helpful 0
- Flag as Inappropriate
Pretty good for the price Overall pleased with the purchase. Like the look, color, size, & structure of the piece. The things you cannot tell from the description are that the cusions are not finished on the bottom so there is no opportunity to flip them if they get stained. The bottom cushions also slide out badly, we put that rubber no-skid stuff underneath that helped a bit, but they still slide out. The sofa is very firm and nearly bouncy. I would recommend it more for a sitting room than a family room, even though i really like a firm couch. You will need to buy bolsters or other throw pillows to put against the arms as they are very hard too. With two toddlers anything we bought would need to be replaced within 5 years anyway b/c they're going to get messed up which is why we bought these, and I think they'll do fine!
Read Moreamandar1 Mar 8, 2012 - Helpful 36
- Not Helpful 0
- Flag as Inappropriate
Peat Sofa First of all this sofa is actually much darker then it looks in the picture. When it arrived I realized I didn't really know what color peat is, so I expected the couch to look like it did in the picture. It is more of a dusty brown, not chocolate but definitely more brown then tan. That being said I'm very pleased with the sofa for its price. My boyfriend didn't seem to have any trouble assembling it, although he is handy. It took him about 30-40 mins I would say. The sofa seems very sturdy so far and the three cushions are firm. Definitely not the most comfortable, but comfortable enough that I have spent Saturdays laying out on the sofa lounging. The sofa cushions arent attached to the couch so sometimes they will slide out of place. I don't know how well it will work with kids, because under the cushions there is a thin material covering the wood base and like I said the cushions will move. Overall I believe this is a good buy for a start out sofa or just an inexpensive sofa.
Read Morefablady Feb 5, 2010 - Helpful 21
- Not Helpful 0
- Flag as Inappropriate
super deal Also bought the loveseat. Very easy to put together. I did it myself, did not need another pair of hands. Read my review under loveseat.
Read Morebethann732 Apr 3, 2012 - Helpful 10
- Not Helpful 0
- Flag as Inappropriate
Great Quality Great couch. I put it together with one friend. Was worried about the back not having cushions but it is very comfortable. Put it together with one friend and was quite simple. Remember to remove the velcro with screwing on the arms. Great and well made couch and worth the money. Wish the love seat was still in stock.
Read Morelindseyhall04 Nov 4, 2011 - Helpful 9
- Not Helpful 0
- Flag as Inappropriate
Excellent value couch Sofa arrived in three packages and was easily assembled in approximately 30 minutes. Construction of components appears solid and well-made.Microfiber has a plush feel to it when brushed.Style works well with a variety of decors.
Read Morezedisdead Jul 20, 2011 - Helpful 9
- Not Helpful 0
- Flag as Inappropriate
Questions & Answers
Hello SaraB, items are restocked as they become available; however, we cannot guarantee an item will be restocked. Thank you for shopping with us.
What color is sage?
Hello ken, we appreciate your inquiry. The sage color option is the light green. We hope this information has been helpful. Thank you for shopping with us!
can I get it in white or lilac?
Hello modesty blaise, unfortunately this sofa is not offered in white or lilac. Please let us know if you have additional questions. Thanks for shopping with us.
Will there be a restock in the grey linen or white linen? If so how can I get updates? We love this couch.
Hello C_Jacobs, items are restocked as they become available; however, we cannot guarantee an item will be restocked. Thank you for shopping with us.
The instructions were not included, where can i find them online
Hello Hallie S., you will be contacted by Customer Care. Have a great day.
Why did you choose this product?
Gorgeous and cheap. Goes with my decor.
The size
What is the color of the couch in the main picture (picture 1, that has all the color swatches beneath it)?
Hello Ryan McGowin, the couch in the main picture is white linen. Thank you for shopping with us!
Is there an estimate on when this sofa might be available in grey linen?
Hello philharmonic89, items are restocked as they become available; however, we cannot guarantee an item will be restocked. Thank you for shopping with us.
Hello, how much does this couch weigh?
Hello Gjb170, the sofa weighs approximately 110 pounds. I hope this helps. Have a great day!
hello, i am going to move into a new apartment. so i want to know that will this back in stock?
Hello phoebs, this is currently in stock. Thank you for shopping with us!
I understand that the total depth is 34 inches. Could you tell me the depth of the seat please?
Hello clvl99, the seat depth is 22 inches for this style sofa. Thank you for shopping with us!
The instructions were not included. Is there somewhere on-line to find those?
Hello riverrain, thank you for your inquiry; you will be contacted by Customer Care.
How many boxes does this sofa come in and what are the dimensions of the boxes? I live in a second floor apartment with a small stairwell! Thanks.
Hello Menchyk, this item comes shipped in 3 boxes. The first is 66.5 inches long x 22.5 inches wide x 8.75 inches high. The second is 31 inches long x 18.5 inches wide x 9 inches high, and the third box is 75 inches long x 11 inches wide x 28.5 inches high. Thank you for shopping with us!
Hi, Is the grey linen couch made out of linen? Or is it all microfiber? Or is it a blend of microfiber and linen? Can I order a swatch of the material? Thank you.
Thank you for your question, epp12. The INSPIRE Q Uptown Modern Sofa is made of microfiber and gray linen is the only color available. Have a great day.
What are the dimensions of the three boxes that this product ships in?
Hello itsbecks, unfortunately this item is out of stock. We currently do not have inventory to check, and cannot guarantee the item will be restocked. Thank you for shopping with us!
Hello, can you tell me what the width of each cushion is in inches? Thank you!
Hello merrymerry, thank you for your inquiry. Unfortunately, the information you have requested is currently unavailable. We will continue to try and answer this for you. You will receive an email notification once an answer is posted. Have a great day.
Hello, could you estimate the price for shipping to Moscow (Russia)? Thank you in advance, Konstantin
Hello Konstantin, taxes, duties, international service fees and shipping charges will be added during checkout. Please add the item to the cart and enter your postal information for the completed price.
Hello, I see from questions and answers below that there was suppose to be the gray option available again mid-November. I was hoping to make a purchase tomorrow 11/21/2014 but definitely want gray. Do you know when this will be back in stock?
Hello jray743, we do not have any updates for this item to be restocked. Thank you for shopping with us.
When will the grey linen color be available?
Hello chelsey6990, this will be available in grey linen the first week in December. Thank you for shopping with us!
Can replacement cushions be purchased?
Hello pdeering88, yes, we do offer replacements for damaged in transit and defect items. Thank you for shopping with us!
Shopping Guides
Cheap Sofas vs Discount Sofas
Sofas and loveseats are quintessential pieces in any living room. When choosing your living room furniture, consider looking for cheap and discounted sofas and loveseats to make outfitting your home a more affordable undertaking. If you view finding loveseats and sofas at stellar prices as an exciting challenge, you can make finding the perfect furniture a fun adventure.
History of the Sofa - Loveseats
Upgrading your living room's look means picking the perfect sofa. Loveseats and sofas are a necessary and complementary addition to any home. Over the years the loveseat has evolved into a natural addition to living rooms across the world. It might surprise you that the loveseat, or settee, was once a new and innovative piece of furniture. Sofas and loveseats have come a long way since then. Keep reading for the latest installation on the history of the sofa, loveseats and other living room furniture.
How to Care for a Microfiber Sofa or Loveseat
Microsuede fabric has a unique texture that accentuates a color's depth and contrast, making it an excellent upholstery choice for furniture. The superior stain resistance of microfiber fabric means that your sofa and loveseat set will be able to withstand the rigors of daily use by active kids and pets. In order to keep your microfiber sofa or loveseat looking its best, some simple care is required.
Trendy Sofas and Loveseats
When it comes to living room fashion, your choice of sofas and loveseats determine whether your home decoration skills are a fashion triumph or flop. Your choice of sofas and loveseats is as important as your living room's paint color and art on the wall. Seating is about more than just providing a place for your guests to rest. Your living room can easily become the center of high fashion if you pick the right furniture. Luckily, picking out the right sofa and loveseat for your living room is easy, thanks to the many fashionable furniture styles available. Keep reading for the scoop on the different types of trendy sofas and loveseats that are available for your living room.
Popular Styles of Sofas Loveseats and Ottomans
Finding the perfect sofas and loveseats for your home is essential. Your living room furniture is an important part of your home decor, so making the right furniture choice is vital. When choosing new living room furniture like sofas, loveseats and ottomans you'll need to consider what kind of fabric, style and look you want for your home. Taking the time to consider all your options will help you make the best choice possible. Keep reading for more ideas about popular styles of sofas, loveseats and ottomans for your home.
How to Decorate with a Blue Sofa
We all have that one piece of furniture we love. Whether it's a blue sofa or loveseat, a red leather chair or a knotty pine wood bookcase that has seen better days, it will forever be a part of your home. If you have one special piece of furniture that you must coordinate into the rest of your decor, do it with style by coordinating colors. Blending a blue sofa into an existing living room, den or recreation area is simple. By adding colorful accents such as pillows, rugs and window treatments, you can easily integrate your favorite blue sofa into your design scheme. Look below to learn how to decorate with a blue sofa.
How to Buy a Loveseat
Not only do loveseats save valuable space in your living room, den, or sunroom, but they also add a cozy atmosphere to the room's design. These petite sofas are perfect for additional seating and for creating conversation areas. By following these tips, you should end up with the perfect loveseat for your home.
Popular Leather Sofa Styles
A leather sofa is a classic piece of furniture, and there are styles that can fit in every type of room. The right one will help you express your style as well as provide you with a comfortable place to sit for many years to come. With so many different leather sofas and loveseats to choose from, you'll want to read about them all to find the one that will best fit your home.
Sofa Buying Guide
As the largest pieces of living room furniture, your sofa and loveseat will influence the the decor of an entire room. However, with all of the types of sofas available, basing your choice solely on looks will only get you so far. Here's what to look for when you are sofa shopping, so you can choose one that is beautiful and functional.
Couches vs Sofas
When shopping for living room furniture, the most important piece is your couch or sofa. It will be at the hub of all your living room activity. In addition to sitting and relaxing on your comfortable couch or sofa, you'll offer this seating to any guests who happen to stop by. Although the terms "couch" and "sofa" are often used interchangeably and they do refer to similar pieces of furniture for the home, there are distinct differences that exist between the two.
Best Sofas for a Modern Living Room
If you're drawn to the modern style of decorating, then you'll want to find a sofa that will be the perfect centerpiece in your living room. Modern sofas are available in many different designs, so you can find the one that will help you get the exact look and feel you want. Here's what to look for when you're shopping.
How to Clean a Leather Sofa
A leather sofa can be a durable and beautiful piece of living room furniture. However, if your leather sofas and loveseats aren't properly cared for, they will lose some of their beauty and can even become damaged. Fortunately, cleaning a leather sofa is simple. About once a month, or after a party or other event when your couch gets lots of use, follow these steps.
Necessary Living Room Furniture - Sofas
Take a good look at your living room furniture. Sofas and loveseats are a staple when it comes to the way your living room looks. Pair your sofa with a loveseat or ottoman, and your living room is well on its way to looking its best. Although most people own living room furniture like ottomans and end tables, few realize what an impact their sofa can have on a living room. Sofas and other accompanying furniture can either tie a living room theme together or break it. Keep reading for more information about sofas.
How to Choose a Good Sofa Bed
Sofa beds are the perfect way to add extra sleeping space to your home. These handy sofas can be added to your living room or even a small home office. When a guest comes to stay the night, they have a comfortable place to sleep just by folding out the sofa into a bed. Some sofa beds are more comfortable than others, though. When you're looking for a sofa bed, comfort is one of the most important aspects. This article should help you learn how to choose a good sofa bed.
How to Clean a Sleeper Sofa
Taking the time to clean your sleeper sofa will help you be prepared for any unexpected guests. In addition to preparedness, you'll also help to cut down on the amount of crumbs and dust bunnies in your home. Sleeper sofas, also called sofa beds, are necessary living room furniture for your home, and taking good care of your sleeper sofa should be a high priority. They're pretty easy to care for, and as long as you perform regular maintenance on your sleeper sofa, it should last you many years. Keep reading for instructions on how to clean a sleeper sofa.
How to Buy a Reclining Sofa
A reclining sofa brings the best of two worlds together: the comfort of a recliner and the size of a sofa or loveseat. Before you buy a reclining sofa, there are a few things to keep in mind that will make your purchase easier and ensure that you are more than pleased with your new piece of furniture.
Best Sectional Couches for Small Spaces
Anyone who lives in a small space knows how hard it can be to fit a sectional sofa into an area that seemingly has no extra room. Large sectional sofas can leave your home feeling cramped. However, over the past few years, finding the best sectional sofa for a small space has become much easier. To begin shopping for a sectional couch, consider the number of people who will be seated regularly in order to determine the ideal size for the space, and be sure to measure the room where you will be placing the sofa.
How to Measure for a Sectional Sofa
Adding trendy and stylish sectional sofas to your home provides you with a comfortable place to sit at the end of the day and adds fashion to your home. A sectional sofa is a popular choice of seating for formal or casual living rooms, recreation rooms and studies. The one drawback to sectional sofas is their size. They're much larger than traditional sofas and allow for less flexibility in furniture arrangements. However, it's easy to overcome that by following these tips on How to Measure for a Sectional Sofa.
How to Maintain a Leather Sofa
If you are planning to buy a leather sofa, you'll want to make sure you know how to maintain the upholstery. A leather sofa can be one of the most comfortable and stylish pieces of furniture in your home. Whether you are considering a leather sectional sofa, sleeper sofa, leather chairs, or any other piece of leather furniture, you can significantly extend their longevity by giving them proper and consistent care. Here are a few tips to make sure your leather sofa will be a favorite furniture piece for years.
The Sleeper Sofa vs a Conventional Sofa
Deciding whether a sleeper sofa or a conventional sofa would be best for your room is a long-term decision. Chances are you'll own your sleeper sofa or regular sofa for several years, maybe even moving it into different homes. Both styles have certain attributes that should be considered before making a decision. Either way, if you choose a sofa to fit your style and requirements, you'll be happy to own it for years to come. Here are a few things to consider about both styles before making a choice.
- |
Shipping & Returns
Usually leaves our warehouse in 1-2 business days. *
Standard Return Policy:
Items must be returned in new or unused condition and contain all original materials included with the shipment. More Details
FINAL SALE EXCLUSION: Items marked as FINAL SALE are not returnable unless the problem you experience is the result of our error.
This item cannot be shipped to Alaska or Hawaii. More details
Shipping Information:
Our standard shipping method is ground shipping. We also offer expedited shipping for most items. Your final
shipping cost and estimated delivery timeframe will be available at checkout.
Standard shipping details
Expedited shipping details
* For your protection, all orders are screened for security purposes. If your order is selected for review, our Loss Prevention Team may contact you by phone or email. There may be a two business day delay to process your order.
** Most Oversize orders are delivered within 1-4 weeks. Some orders may take 6 weeks to be delivered.


text:
Hi Everyone! Kiki from Kiki and Company back to share another free printable for you this month. I don't know about you, but these months are FLYING by! Whew! May is right around the corner and so is celebrating the most lovely ladies in our lives, our mothers! Who doesn't LOVE Abraham Lincoln's famous mother quote: I made you a sweet print that you can give to the mothers in your life (or hang … [Read more...]
Cream Cheese Guava Pastries
Hey guys, I'm Kelsey from Poofy Cheeks and I am stopping by to share a Cream Cheese Guava Pastry recipe! My family loves the cream cheese guava pastries from our local grocery store but truth be told they are pretty pricey so I decided to make my own and they were absolutely delicious. My husband has been asking me to make more for weeks so I decided to make another batch and share the recipe. … [Read more...]
DIY Floral Print Artwork
Hi guys, it's Holly from My Sister's Suitcase, and I can't wait to show you how I made this custom artwork in less than 10 minutes! I love to create seasonal decor for my home, and I needed something new for Spring. I also wanted to incorporate some beautiful watercolor floral fabric I've had sitting in my craft room. Using materials I already had at home, I made this fun floral … [Read more...]
EOS Lip Balm Spring Printable Gift Idea
Hi! It's Aimée and Bettijo here from Paging Supermom. Are you as excited for spring as we are? Since we're enjoying spring flowers and completely obsessed with EOS lip balms, we combined the two to create the perfect gift for teachers and friends. While any colors of the EOS balms would look cute as the center of the flower on the printable, we opted for the Strawberry Sorbet, Summer Fruit … [Read more...]
Easter Finger Puppets
Hi everyone! Kiki from Kiki and Company here to share another free printable with you this month. I LOVE Easter time. I know today is all about green, but I want to get you all excited about pastels today. Ha! One of my kiddos favorite things to do is to play with little characters. I have made them little puppets through all stages of their life, so today I thought I'd add an Easter set to their … [Read more...]
Chicken Alfredo Flatbread Pizza
Hey guys! I'm Kelsey from Poofy Cheeks back with another recipe and here at our house I love finding new ways to make our favorite foods. I like to take ingredients from our favorite dinners and rework them into something different. Doing this makes things easier on me but doesn't make dinner seem like the same repetitive dish after another. Chicken Alfredo is one of the dishes my entire family of … [Read more...]
DIY Corkboard String Art
Hey everyone, it's Holly from My Sister's Suitcase and I'm excited to share an easy decor idea with you today! I have been wanting to try my hand at string art, and when I found these darling wooden push pins in the Target dollar spot I thought it would be fun to create one with corkboard. No nails and hammer needed for this project... To make this DIY corkboard string art, you'll just need a … [Read more...]


text:
change location
Full service Wedding service, Event coordinating, Catering, DJ, Photography, Fresh Flowers, wedding rentals and much more.
View Profile »
An idyllic seaside destination for the biggest day of your life!
1 Photo
Small manual bingo cage for use with ping pong size Bingo balls. It stands 17 inches tall and comes with a set of balls and a masterboard. (more)
Experience the newly renovated Banquet Facility at Belmar Golf Club. With seating for up to 300 people, our Banquet Facility, overlooking our Championship (more)


text:
Ads by Google
This topic is discussed in the following articles:
use along Tigris-Euphrates river system
Just south of the river below Al-Ramādī lie Lakes Al-Ḥabbāniyyah and Al-Milḥ, both of which are large depressions into which excess Euphrates water is diverted by controlled escape. A canal links Lake Al-Ḥabbāniyyah to Lake Al-Tharthār north of the river, which in turn draws overflow from the Tigris by canal. Between Al-Ramādī...


text:
Hybrid Cloud For Dummies
360 pages
June 2012
US $29.99 Add to Cart
Table of Contents
Author Information
Judith Hurwitz is President and CEO of Hurwitz & Associates, specializing in cloud computing, service management, information management, and business strategy. Marcia Kaufman is COO and partner of Hurwitz & Associates, focusing on the cloud infrastructure, information management, and service management. Dr. Fern Halper is a partner at Hurwitz & Associates with extensive expertise in information management, big data, and analytics. Daniel Kirsch is an analyst at Hurwitz & Associates, focusing on cloud compliance, governance, security, and privacy.


text:
Upcoming Movies
Top 10 Horror
Contact Us
The Latest Horror Movie News Served Fresh Daily Since 2005
Tom Burke
Only God Forgives
Posted by The Cryptkeeper | Posted 516 days ago.
Julian, a drug-smuggler thriving in Bangkok's criminal underworld, sees his life get even more complicated when his mother compels him to find and kill whoever is responsible for his brother's recent death.
Horror Writers Wanted!
Shared 28 Times
The House On Pine Street (2015) Review
Shared 305 Times
First Trailer for the Upcoming Cannibal Film 'Ghoul'
Shared 251 Times
Lucy Lawless Joins 'Ash Vs Evil Dead'
Shared 205 Times
Jen & Sylvia Soska Announce Their Debut Graphic Novel Kill-Crazy Nymphos Attack!
Shared 196 Times
First Official Clip from Jon Watts' Clown
Shared 169 Times
New Official 'Homicycle' Trailer Inside by Chris Savage
Official International Trailer for Insidious: Chapter 3 by Chris Savage
First Trailer for Bunker of the Dead 3D by Chris Savage
[Review] Zombieworld Uses Practical Effects That Blow Your Mind, Literally by Stephanie Joyce
First Official Clip from Jon Watts' Clown by Chris Savage
[Trailer] First Look at The Void by Chris Savage
First Trailer for the Upcoming Cannibal Film 'Ghoul' by Chris Savage
Terror Is Unleashed in New Theatrical Trailer for Crying Wolf 3D by Chris Savage


text:
as i'm not getting the exact main point of 2 DES and 3DES. I would like to know the difference between the two, why 3 DES is chosen on 2 DES?
Double-DES is two successive DES instances, while Triple-DES is three successive DES instances. We use 3DES and not 2DES because 2DES does not yield the security increase that you would believe. Namely, 2DES uses 112 key bits (two 56-bit DES keys) but offers a security level of about 257, not 2112, because of a "meet-in-the middle attack" which is well explained there (not to be confused with "man-in-the-middle", a completely different concept). Similarly, 3DES uses 168 key bits, but offers "only" 2112 security (which is quite sufficient in practice). This also explains why 3DES is sometimes used with a 112-bit key (the third DES key is a copy of the first): going to 168 bits does not actually make things more secure. This can be summarized as: we use n-DES because a simple DES is too weak (a 56-bit key can be brute-forced by a determined attacker), but in order to really improve security, we must go to n ≥ 3. Of course, every additional DES implies some computational overhead (simple DES is already quite slow in software, 3DES thrice as much). |
The number in front of DES is how many times DES is run. DES simply takes input, runs it through DES once and then has the final output. DES however has some weaknesses, so 3DES was used to help counter them. 3DES runs through one instance of DES, feeds that output as input to another instance of DES and finally that output goes in to a third. 2DES would be similar, but only going through two DES algorithms. The reason we use 3DES and not 2DES is that 2DES doesn't actually give us that much more security than DES. If we take a bunch of possible plain-texts and start trying to encode them and simultaneously take a bunch of encrypted values and start decrypting them, we only have to look for where they meet in the middle with the same value. Those intersections then reveal the key. 3DES avoids this because of the middle step. We'd need to work a third operation to tell if they met in the middle and thus we can't simply look for where the first and last operation produce the same value. |


text:
PDA + iPad
Dominic Rushe: Amazon's low-cost entry into the tablet market will be good for consumers and content providers
A $2,855 fine won't break the bank, but the ruling is just the latest in a series of regulatory crackdowns against collecting users' location data. By Jemima Kiss
Student discovers hole in iPhone app that shows what tablet version will look like. By Jemima Kiss
Publishers now able to report smartphone and tablet figures as well as website and print statistics. By Josh Halliday
Jemima Kiss: It won't cause as much a stir as the first generation iPad launch but it could iron out some irritants and be worth an upgrade
The next generation 'Jesus tablet' reportedly will be announced next week – quashing rumours of a setback
Apple's move to take a greater share of cash from newspaper app subscriptions may instead allow Google to take a bite. By Josh Halliday
Josh Halliday: Corporation's new app for Apple's popular tablet device is a hit, with some minor annoyances
Matt Webb of Berg explains the new "attention economics" of digital publishing. By Jemima Kiss
The 'iPad newspaper' that has been Murdoch's pet project for the best part of a year will be revealed next week – how much do we know about it?
An up and down year for both Google and Apple, 2010's big games and significant political developments in the tech world all feature in our annual review
Emily Bell: The News Corp boss will probably lose the $30m he's rumoured to be investing in a post-print collaboration with Apple
Dan Sabbagh: Digital devices such as the Kindle and the iPad have media companies quivering with excitement – but will people really use them to read newspapers and magazines?
The US title takes us back inside the newsroom for All The President's Men revisited (2.0?)
Publisher launches iPad applications for two of its upmarket glossies. By James Robinson
Want to break free of Helvetica? We've got just the app you need. By Jemima Kiss
Pew has found tech coverage favours Steve Jobs' empire, with 42% of pieces praising the company. By Jemima Kiss
Technology blog Apple handhelds streamed 5m iPlayer programmes in July – 6,000 on Android 2.2 devices
A peek at official figures shows what BBC is missing by not supporting older Android devices
Greg Clayman is leaving his post as MTV's executive vice president, digital distribution and business development, and is jumping to News Corp (NSDQ: NWS) to manage its tablet-based news organisation, MediaMemo reports. By David Kaplan
Josh Halliday: A survey shows that Apple's tablet device is popular among readers and gamers
paidContent: While display ads on Times sites decline, advertorials are placed outside the paywall. By Robert Andrews


text:
- Filed Under
The mother of a fisherman killed by a distracted driver on an Eau Gallie bridge earlier this year is taking the driver to court. She wants answers.
"What was so important about the text he was reading? Who was it from?" said Christian Lindbaek, the attorney representing Kim Wright in the wrongful death lawsuit that was filed earlier this week.
The lawsuit claims an unspecified amount of damages from the driver, Vincent Worbington, to cover reimbursement for Wright's son's estate, burial costs and "mental pain and suffering." ...


text:
Nov 8th, 2008
2:47 pm
November 8th, 2008 | Uncategorized
Another Yale miscue
Yale's playing with fire. The offense was driving down the field again, but this time the drive was halted by a poorly thrown interception by Hart. The Yale defense has been able to keep the Bear offense at bay thus far, but an explosive offense like Brown's can explode at anytime. Yale can't continue giving them extra opportunities, and not take advantage of their own.


text:
June 2, 2012 Southern Baptist's Richard Land loses radio program over plagiarism accusations |
Richard Land, the embattled Southern Baptist leader who had been accused of plagiarism when he claimed on his radio program that civil rights leaders and President Obama were using the Trayvon Martin case to fuel racial tension, has been stripped of his radio show. He will, however, keep his post as head the the Southern Baptist Convention's Ethics & Religious Liberty Commission. Religion News Service reports: Read the rest here. The Washington Times column from which Land allegedly lifted is here. And for a "layered" look at Land that gets beyond the typical hero or villain "cardboard cutouts," Bobby Ross points to this story in the Tennessean. |
JewishJournal.com is produced by TRIBE Media Corp., a non-profit media company whose mission is to inform, connect and enlighten community © Copyright 2015 Tribe Media Corp. |


text:
Welcome to this site, where you can search for epic ringtones for your mobile phone. Today we have a ringtone of "Melt The Snow" by Shayne Ward as well as 962 other ringtones by Shayne Ward. "Melt The Snow" is the best track from the "Breathless" album that was released by Shayne Ward at their recording studio together with other 20 tracks. You can listen to all 25 Shayne Ward – "Melt The Snow" ringtone variations available here and download it for free right now. You can also look at other 4 albums produced by Shayne Ward for all time. "Melt The Snow" is referred to Pop, and you may listen to a huge amount of Pop ringtones absolutely for free. And finally, we have collected lyrics for this track and you can view it here as well. So feel free to browse, listen, download ringtones at Audiko.net. Make your phone sound cool!
Shayne Ward Melt The Snow Ringtone
Similar Ringtones
Browse Genres
Albums by Shayne Ward
Top ringtones by Shayne Ward
New ringtones
- MaximBady - Ding Dong
- Nashville Cast Feat. Sam Palladio & Clare Bowen - Fade Into You
- Clare Bowen & Sam Palladio - Casino
- twine - Guided Relaxation Dub
- Victoria Justice ft. Ariana Grande - L.A. Boyz
- Philipp Dittberner & Marv - Philipp Dittberner & Marv - Wolke 4 (Original Mix) | Out NOW
- Kylie Hensley - I Love It
- www.dal3-g.net نغم الغربية - زايد الصالح موجوع قلبي
- Ruth Fazal - Worship Music
- Gulraj Singh - Pakeezah Funmaza.com


text:
- Find trusted companies
- Search results listed by WWDC Rank Score
- Read 10178 independent reviews
- Request quotes in a click
- Get expert advice for free
Which Web Design Company helps you find the right web designer or digital agency for your business needs.
Featured Website Designers
TA Webmedia
Member since 8 Sep 2010
TA Web Media is a company that provides professional customized solutions in web designing...
Toolkit Websites Ltd
Member since 26 Oct 2009
Established in 1999 and with over 2000 clients spread across the UK, we specialise in designing...
UK, Southampton, Southampton
Immersive Media
Member since 9 Jul 2007
We're a Web Design & SEO agency based in Greater London, having delivered over 500 engaging...
Cozy Digital
Member since 14 Nov 2012
If you're looking for cutting-edge, bespoke responsive web design services or want to achieve...
New companies
Cole Wiebe + Partners
Member since 17 Jan 2015
We are a small boutique content marketing agency offering consulting/coaching, SEO, copywriting,...
CA, British Columbia, Vancouver
Bannerbuzz Canada
Member since 7 Jan 2015
Bannerbuzz make you visible whether it's indoor or outdoor advertising or event signage any...
CA, New Brunswick, Toronto
KW, Inc
Member since 5 Dec 2014
Do you want to impress customers with your website? Looking for a professional Web Designer...
Magnetic Media
Member since 6 Nov 2014
Our primary goal is to help clients build a strong online presence, through conversion-oriented...
Net World Solutions, Canada
Member since 2 Nov 2014
Net World applies individual approach to every project and every customer. And because we rely...
Red Cherry Web Design
Member since 22 Oct 2014
Red Cherry has offices in both Kelowna, BC and Calgary, AB. We work closely with you to develop...
Member since 18 Sep 2014
When you are searching for a Vancouver web design, visual planner, you need to search for somebody...
CA, British Columbia, North Vancouver,
Member since 10 Aug 2014
Yassin&Ward started in 2014 when the brilliant and talented duo, Meego Yassin and Jaime Ward...
CA, British Columbia, Vancouver
VivosWeb Inc
Member since 4 Aug 2014
VivosWeb is a revolutionary full service digital house providing broad solutions covering all...
Smartt: Digital Consulting Agency
Member since 24 Jul 2014
Smartt offers integrated support in branding, web development, digital marketing, and IT services...
CA, British Columbia, Burnaby
Artik Design
Member since 24 Jul 2014
Artik Design provides comprehensive web design solutions including Web Design & Development,...
Edmonton Web
Member since 11 Jul 2014
LAUNCH Edmonton Web is known for designing websites that deliver high traffic and generate...
Just rated
Kaatt's WebDesign has been doing our soccer website for about 3 years now. He worked with...
Reviewed on 23 Feb, 2015
Charlene Owen
— Kirkland Lake Soccer Club -
I have worked with Cyndi Roberts of Inspired by Change Communication Design for a few years...
Reviewed on 8 Jan, 2015
Sue Meyer
— CortiSLIM International, Inc. -
Dear Anna: I would like to thank you for the creative design that you developed for my web...
Reviewed on 31 Jul, 2014
— timoridge group -
Thanks for all the little extras and the photography turned out so AWESOME!!!!!! We love what...
Reviewed on 8 Jul, 2014
— Fly Mart -
Several months ago we decided we needed a new, fresh look and feel for our website. We...
Reviewed on 26 Jun, 2014
Andrew Salamon
— Outdoor Displays -
We have had our website made and maintained over 2 years ago with iTec Web Design and i have...
Reviewed on 4 Apr, 2014
— Polmax Automation Inc. -
From my initial consultation right through to the final product, iTec was truly a great company...
Reviewed on 28 Mar, 2014
Dino Colozza
— Lancaster Custom Cabinets & Closets -
iTec Web Design did an amazing job. They were great throughout the entire process, always available...
Reviewed on 28 Mar, 2014
— Junk Stars -
Great experience working with Anna at ITec Web Design. We brought Her our design, she delivered...
Reviewed on 20 Feb, 2014
It was a pleasure working with Salwan who did the project management for my website. My website...
Reviewed on 21 Jun, 2013
Fred Jameson
— Great Lakes -
We approached Kaatt's WebDesign with the task of creating us a new online sports community....
Reviewed on 2 Jun, 2013
Scott K.
— Yeah Sports Network -
We at Tero Consulting have relied on AWT's marketing services to optimize our return on investment...
Reviewed on 5 Mar, 2013
Louden Butters
— Tero Consulting ltd
Recent projects
Project date Apr 1995
Sandy Foster
Accomplished recording artist required an updated website that allows visitors to listen...
By Brooding Artist Website Design
Project date Mar 2015
Graeme Morton
To restart his marriage commissioner service, this client needed a modern, mobile‑friendly...
By Brooding Artist Website Design
Project date Feb 2015
Greater Sudbury Ball Hockey League - 2013 Edition
The Greater Sudbury Ball Hockey League (GSBHL) is a league for those who are passionate...
Project date Jul 2013
Chisnell Plumbing
Chisnell Plumbing is a plumbing service contractor located in Sudbury, Ontario who services...
Project date Jan 2015
Kyle Yasinski Portfolio Site
Kyle Yasinski is a computer programmer from Edmonton, Alberta.
Project date Jan 2014
Seconds Better is a new and second hand item website based solely online in conjunction...
Project date Oct 2013
Heather Leblanc
Heather LeBlanc is a painter from Toronto, and is committed to creating meaning. She is...
Project date Oct 2013
Deep Cove Brewers and Distillers
At Deep Cove Brewers and Distillers the emphasis is on the highest quality of tradition...
By Adaptive Marketing Solutions
Project date Nov 2014
Zoomer Lifestyle
Zoomer Lifestyle provides income development options for baby boomers heading into retirement....
Project date Nov 2014
Whitewolf Design Co.
Whitewolf Design has been hand crafting websites in the Squamish / Whistler area since...
Project date May 2014
Dynamic Property Management
Dynamic Property Management manages rental properties in the Squamish, BC area.
Project date Sep 2011


text:
Skip to content. | Skip to navigation
"Little House" backyard - next door to the Library.
(Sales are held inside the house if raining.)
No Scanning Allowed
8:30 a.m. to Noon
Regular Sale
(books from $.25 to $4.00 each)
Noon to 1:00 p.m.
1:00 p.m. to 3:00 p.m.
Bag Sale
($4.00 a bag, bring your own.)
LOCATION321 S. Prairie St.Bethalto, IL 62010618-377-8141
Go to Google Map
HOURSMon-Thu: 9am-8pmFri: 9am-7pm Sat: 10am-5pmSun: 1pm-5pm
Holiday Closings:
—Gareth Roberts


text:
Display videos easily (from YOUTUBE, VIMEO, DAILYMOTION) with lightbox effect. Especially, all your videos will be fitted on all layouts.
Requires: 3.0.1 or higher
Compatible up to: 3.9.2
Last Updated: 2015-2-16
Active Installs:
0 of 3 support threads in the last two months have been resolved.
Got something to say? Need help?


text:
Argentine leader refuses to bow over FalklandsAFP March 14, 2013, 11:41 am TWN BUENOS AIRES -- Argentine President Cristina Kirchner, her approval rating plummeting, has refused to recognize the results of a referendum in which the people of the disputed Falkland Islands voted to remain British.
The vote in the sparsely populated South Atlantic archipelago that triggered a war between the two nations in 1982 was a "parody," she said. Even the United States, Britain's firmest ally, acknowledged Argentina's claim. British Prime Minister David Cameron had earlier urged the Latin American country to respect the wishes of 99.8 percent of the islanders who voted "yes" to staying a self-governing British territory, according to official results. The islanders organized the vote in response to increasingly bellicose sovereignty rhetoric by Kirchner, and only three of the 1,517 valid ballots — on 92 percent turnout — were cast against the islands staying under British rule. Kirchner's government had dismissed the referendum as meaningless and said it would not affect its claims on the Falklands which it calls "Las Malvinas." She reiterated her displeasure late Tuesday at an event at the presidential mansion. "What is important today is the United States' position about this kind of parody of a referendum," Kirchner said. "The State Department spokeswoman said that they continue to recognize that there is a sovereignty dispute between Argentina and Britain." The United States earlier said it took "note" of the islanders' vote, but refused once again to take sides in the dispute. "The residents have clearly expressed their preference for a continued relationship with the United Kingdom," State Department spokeswoman Victoria Nuland said. "That said, we obviously recognize that there are competing claims." Argentina failed to seize the islands back from Britain in the brief 1982 war. |


text:
Thanks for redeeming.
{{else}}Success! Thanks for repurchasing.
{{/if}} {{else}} {{#if Expired}}Increase my visibility!
{{else}} {{#if IsMultiPack}}{{#if HasMultiPack}} You have {{MultiPackCount}} top spot(s) left. Now loading you into the search listings... {{else}} You have used all top spots. Now loading you into the search listings... {{/if}}
{{else}}We are loading you into the search listing pages...
{{/if}} {{/if}} {{/if}} {{/if}}{{Current}} just saw you!
{{/if}} {{#if LastTopSpotPurchaseIsMulti }} {{#if HasAnyTopSpot}}{{#if HasFreeTopSpot }} {{ UnclaimedTopSpotFree }} Free {{/if}} {{#if HasPaidTopSpot }} {{#if HasFreeTopSpot }} & {{/if}} {{ MultiPackCount }} {{/if}} Top Spot{{#if Plural}}s{{/if}} Left
{{else}}0 Top Spot{{#if Plural}}s{{/if}} Left
{{/if}} {{else}} {{#if HasFreeTopSpot }}{{ UnclaimedTopSpotFree }} Top Spot{{#if Plural}}s{{/if}} Left
{{/if}} {{/if}} {{else}} {{#if HasResults}}{{Current}} see you now!
{{else}} {{/if}} {{/if}}You can now invite anyone to meet at your favorite Starbucks.
Limited-time feature
37 year old man | Fruitland, ON, CAN | Seeking women 26-40 within 30 miles of Stoney Creek, ON
Active within 24 hours
I'm an honest and hard working guy who is new…
I'm an honest and hard working guy who is new to this online dating stuff. I have no major expectations here just trying it out and hopefully meet some new and interesting women. I have no problems going out for a night on the town to enjoy a few drinks and i'm just as comfortable hanging in and watching tv or a good movie.
Coffee and conversation , Cooking , Dining out , Movies/Videos , Museums and art , Music and concerts , Exploring new areas , Playing sports , Travel/Sightseeing , Watching sports
Football, Martial arts, Other types of exercise, Running, Tennis / Racquet sports, Weights / Machines
I exercise 3-4 times per week.
I have Dogs
I like Birds, Cats
Some other viewpoint
Anywhere out west where you can do some decent snowboarding.
Music is probably my favorite passtime, I love all sorts but you can't go wrong with rock n roll. As far as tv goes it's not that important but i love Seinfeld.
I enjoy hanging out with friends when i have the time. If i'm hanging around the house i love watching a good movie or reading a book, or playing the guitar. When the snow comes in the winter I love hitting the slopes for some snowboarding.
Right now i'm reading The book of Five Rings. I'm a huge Hunter S. Thompson fan
Him | What he is looking for | |
Appearance | ||
Height: | 5'10" (178cms) | 5'0" (152cms) to 6'0" (184cms) |
Body type: | Athletic and toned | Slender, About average, Athletic and toned, Full-figured |
Eyes: | Blue | No preference |
Hair: | Light brown | No preference |
Lifestyle | ||
Smoke: | No Way | No preference |
Drink: | Social Drinker | No preference |
Occupation: | Labor / Construction | No preference |
I'm an electrician |
Income: | $100,001 to $150,000 | No preference |
Relationship: | Never Married | No preference |
Have kids: | No | No preference |
Wants kids: | Someday | No preference |
Background | ||
Ethnicity: | White / Caucasian | No preference |
Born in Canada but my parents are both from Croatia |
Faith: | Christian / Catholic | No preference |
I'm born an raised Catholic but i'm not practising |
Languages: | English, Other | English |
Education: | Some college | No preference |


text:
Celebrating YOU precious ladis thus Christmas
My husband and I received so much support and love from my DS mama's we could never thank you enough!
Check out my blog and possibly win a gift card! BY YOUR BEDSIDE |
Ugh prematurely sent this through!!
Anyway, check out my link to my blog! We are finding out the gender of baby #4 on Christmas and want to include all of you!! |
How do I find your blog?
Re: Celebrating YOU precious ladis thus Christmas
Click on by your bedside:)
Is this a thing I'm not seeing because I'm mobile??? Or am I just SUPER confused and out of it?
I can post the link into the post! But yes you can't see it because your mobile :(
What could it hurt ;)! A great way to get $10 for that fluff you want!
All times are GMT -6. The time now is 09:45 PM. |
Powered by vBulletin® Version 3.8.4
Copyright ©2000 - 2015, Jelsoft Enterprises Ltd.


text:
Review Summary
Pour a dime-size drop of Phelityl Pre-Cleansing Oil into palm, smooth over face. Follow with your prescribed cleansing bar.
Shipping your purchase is easy on belk.com. Depending on the destination of your package, you can expect it to arrive within 4-7 business days. Shipping Information
Returns are easy on belk.com. Easy returns
Bonus Offer!
Free Gift!
Receive a Moisture Rush Kit FREE with any $125 or more Erno Laszlo purchase.
Kit Includes:
• TIMELESS Serum (0.5-oz./15 ml pump)
• HYDRA-THERAPY Skin Revitalizer (0.5-oz./15 ml pump)
• HYDRA-THERAPY Skin Vitality Mask (1 application)
Limited quantities available. Order yours today!


text:
I'm feeling a bit tired and dizzy today as I was up until 1am last night! No I wasn't out clubbing but was perfecting my recipe for Wholemeal Apple Hot Cross Buns. I'm not much of a one for planning, indeed I'd intended to make a Hot Cross Bread & Butter Pudding this week but suddenly I found myself deciding to actually make Hot Cross Buns which I had only ever made once at school. I didn't really have much of a relationship with bread making in my youth and it's only in the last couple of years that it's become a passion of mine. Therefore I felt it was high time that I made my own Hot Cross Buns! I'd seen a block of marzipan in the cupboard and I knew I had currants so armed with my old school recipe I started my bake.
Well the first hurdle was that I only had strong wholemeal flour and not white so my marzipan idea went out of the window. "I know" I thought, I'm sure I've seen Wholemeal Apple Hot Cross Buns for sale I'll make those! A quick google told me that in a taste test some Apple & Cinnamon ones had only scored 4.5 out of 10 so I decided to stick with the traditional mixed spice. I played about with the recipe I had chopping and changing things here and there but stuck to the one rising, which is where I tripped up. After baking, out came some small, slightly over cooked but delicious hot cross buns which they were too close in texture and not like the light fluffy ones you buy in a baker's or supermarket.
Sometimes I might just give up on a recipe but I could see that there was huge potential here. I just needed to tweak a few things like adding a bit more yeast, giving the dough an extra rise, increasing the proving time and lowering the oven temperature. So at 12.45pm last night (or should I say this morning) I was giving my husband a portion of buttered Hot Cross Bun and asking his opinion. He did protest that he didn't want to eat just before going to sleep but I was insistent – "perfect" he said, after finally relenting to my request. "Great, I've cracked it" I said and went to bed tired but happy!
So the moral of the story is, Hot Cross Buns don't like to be rushed. I hope you give these Wholemeal Apple Hot Cross Buns a go this Easter as they are totally delicious and far healthier than their white cousins
Happy Easter to you all!
As my Wholemeal Apple Hot Cross Buns are such good value compared to shop bought ones I'm entering them into Credit Crunch Munch which I am hosting this month and which I jointly run with Helen of Fuss Free Flavours. I'm also entering Simply Food's Sweet Treats for Easter challenge. Then there's Jibber Jabber's Love Cake event where the theme is Springing into Easter, I may be bending the rules here a bit regarding cake!. Spring into Easter is also the theme for Treat Petite this month hosted by Cakey Boi and alternately with The Baking Explorer. Finally I'm entering the Made with Love Mondays which is hosted by Javelin Warrior's Cookin w'luv as these buns are totally made from scratch.
- 75mls Milk (hand hot)
- 75mls Water (hand hot)
- 1 tsp Caster sugar
- 12g Active yeast (dried, not fast action)
- 325g Strong wholemeal flour
- 50g Butter
- 1 tsp Mixed Spice
- ½ tsp Salt
- 25g Caster sugar (I keep a vanilla pod in mine or you could substitute a tsp for vanilla sugar)
- 50g Currants
- 1 Apple, chopped into small pieces (I used small Braeburn)
- 1 egg lightly beaten
- Crosses:
- 50g Plain flour
- 5 tbsp water approx.
- Sugar Glace:
- 2 tbsp Granulated sugar
- 2 tbsp Water
- Mix the warm milk and water with the tsp of sugar and sprinkle on the yeast, set aside while you prepare the rest of the ingredients (a nice froth should build up).
- Put the flour in a large bowl and cut the butter into it and then rub into the flour to form fine crumbs.
- Mix in the mixed spice, salt, caster sugar, currants and apple thoroughly.
- Make a well in the centre and add the yeast mixture and beaten egg and form a dough – I used my hand for this as you can gauge the consistency better – adding extra flour or milk if needed.
- Once you have cleaned the sides of your bowl with the dough, tip out onto a work surface and knead for 10 minutes.
- Then put the dough in a lightly oiled bowl, cover with cling film and leave in a warm place for 1 – 1 ½ hours until doubled in size.
- Once risen turn out onto a lightly oiled work surface and knock back all the air and knead until back to its original size.
- Make 12 balls of dough (I weigh the dough and divide the figure by 12 so mine weighed 65g each). I also knead each ball into a neat bun shape.
- Place the dough balls onto a lightly greased baking tray 3cm apart, cover in lightly oiled cling film and put to rise for about 45 minutes or until doubled in size.
- Meanwhile make up the cross mixture by mixing the flour and water together to make a smooth paste.
- Place paste in a piping bag with a small plain nozzle or make your own out of baking paper and snip off the corner when ready to use.
- Make the glaze by heating the sugar and water in a small pan until the sugar has dissolved.
- Pre-heat the oven to 200⁰C.
- When the buns have risen mark each one with a cross using the side of a metal scewer (so that you have a line to fill with the cross mixture).
- Pipe the flour paste crosses onto the buns working all the way in one direction across the buns and then in the other.
- Bake for 12 – 15 minutes (turning towards the end if necessary for an even bake).
- Once ready take out of the oven and using a pastry brush paint the glaze over each bun.
- Place the buns on a wire rack and either serve warm or cold with butter.


text:
Music Articles A Paul Robeson 'Portrait' on DVD March 26, 2007 A new Criterion four-DVD box set — Paul Robeson: Portraits of the Artist features several of Robeson's films and an abundance of documentary material. Listen Loading… Playlist Download Embed Embed Close embed modal <iframe src="http://www.npr.org/player/embed/9137105/9137109" width="100%" height="290" frameborder="0" scrolling="no">
Music Articles 'Ol' Man River': An American Masterpiece May 31, 2003 NPR's Scott Simon and cultural commentator Murray Horowitz reflect on the impact of "Ol' Man River." It's the 75th anniversary of Paul Robeson's powerful recording of the hauntingly beautiful song from Show Boat. Listen Loading… Playlist Download Embed Embed Close embed modal <iframe src="http://www.npr.org/player/embed/1279965/1281622" width="100%" height="290" frameborder="0" scrolling="no">
Music Articles Paul Robeson April 9, 2003 NPR's Tavis Smiley talks to St. Clair Bourne about his new documentary, Paul Robeson: Here I Stand. Real Media Windows Media
Music Articles Worthy Project May 21, 2002 Host Tavis Smiley highlights this month's WORTHY project. We hear about Paul Robeson from WORTHY scholar Dennis Nelson. And Tavis also sits down with the son of Paul Robeson, Paul Robeson Jr. who authored the book, The Undiscovered Paul Robeson: An Artist's Journey, 1898 — 1939. Real Media
Music Articles Writer PAUL ROBESON, JR. April 26, 2001 Hes just written a new memoir called The Undiscovered Paul Robeson, the first of a two part series on his father, the famed actor, singer and athlete. He talks about his fathers rise in show business and what it was like growing up as the son of an icon. He lives in Brooklyn, New York. Real Media
Music Articles Paul Robeson April 9, 2001 Host Bob Edwards takes a look at a new book about the singer and actor Paul Robeson. The Undiscovered Paul Robeson was written by his son, Paul Robeson Jr. Real Media


text:
Long-Term Stage, Stage-Residual, and Width Data for Streams in the Piedmont Physiographic Region, Georgia
Open-File Report 2009-1205
- By:
- Jeffrey W. Riley and Robert B. Jacobson
- More information: USGS Index Page (html)
- Download citation as: RIS
This report presents the data used to assess geomorphic adjustment of streams over time and to changing land-use conditions. Thirty-seven U.S. Geological Survey streamgages were selected within the Piedmont physiographic region of Georgia. Width, depth, stage, and discharge data from these streams were analyzed to assess channel stability and determine if systematic adjustments of channel morphology could be related to time or land use and land cover. Residual analyses of stage-discharge data were used to infer channel stability, which could then be used as an indicator of habitat stability. Streamgages, representing a gradient of urbanization, were selected to test hypotheses regarding stream stability and adjustment to urban conditions. Results indicate that 14 sites exhibited long-term channel stability, 11 were degrading, 6 were aggrading, and 6 showed variability in response over the study period.Geospatial Extents
Additional Publication Details
- Publication type:
- Report
- Publication Subtype:
- USGS Numbered Series
- Title:
- Long-Term Stage, Stage-Residual, and Width Data for Streams in the Piedmont Physiographic Region, Georgia
- Series title:
- Open-File Report
- Series number:
- 2009-1205
- Edition:
- -
- Year Published:
- 2009
- Language:
- Publisher:
- U.S. Geological Survey
- Contributing office(s):
- Georgia Water Science Center
- Description:
- vi, 48 p.


text:
Connect with Us
Latest news, top stories, and community events,
Army soldier suspect in killing of Afghan civilians reported Lake Tapps homeowner
An Army soldier suspected in the massacre of 16 Afghan has been identified according to Tacoma News Tribune as Army Staff Sgt. Robert Bales, who owns a home on Lake Tapps.
This story will be updated as soon as more information is available.
Latest news, top stories, and community events,
delivered to your inbox.
Trending Stories Apr 20 - Apr 27
We encourage an open exchange of ideas on this story's topic, but we ask you to follow our guidelines for respecting community standards. Personal attacks, inappropriate language, and off-topic comments may be removed, and comment privileges revoked, per our Terms of Use. Please see our FAQ if you have questions or concerns about using Facebook to comment.
Read the Apr 22
Green Edition
Browse the print edition page by page, including stories and ads.
Browse the archives.
Friends to Follow
View All UpdatesLocal display advertising by PaperG


text:
Wild Roses: Season 1, Episode 7Love and Loss (17 Feb. 2009)
(awaiting 5 votes)
Reviews: write review David throws 'family embarrassment' Peter off the McGregors' Montrose estate. Maggie worries as the jacket Jude gallantly gave Charlotte contains weed and grounds her. Pete sees Kate kiss '... See full summary » Director:Don McBrearty |
0Share... |


text:
Like Violet, Lavender and Lilac, Ianthe is a purple flower name. Chosen by the poet Shelley for his daughter, Ianthe has a poetic, romantic, almost ethereal quality. In the ancient myth, she was the daughter of Oceanus, supreme ruler of the sea, and also a Cretan woman so beautiful that when she died the Gods made purple flowers grow around her grave.
Iantha is also used.
Ianthe was a favorite of the pastoral poets of the seventeenth century and then again in the early nineteenth. She appears in the works of Shelley, Barbara Pym and Georgette Heyer. Writer Richard Brautigan named his daughter Ianthe.
Lists containing Ianthe:
- Creative Baby Names
- Flower Names for Girls
- Vowel Baby Names for Girls
- Mythological Baby Names for Girls
- Cool Baby Names That Start With I
Inspired by Ianthe?
Discover 1000s more amazing names you'll love with NameHunter
Hunt Me Some NamesAround The Web


text:
So is there any situation that lends itself to ridding an endomrph tire in the rear ? I switched to a nate in the rear/larry ft. I dont know if I should keep my endo for future use.So far I ride mostly snow packed trails, but might ride some desert single track in the future.
I'm also thinking about putting a Nate up front as well. The only down side to the nate I can see is it seems to roll slow, but it has heaps of traction.
Results 1 to 15 of 15
SEA OTTER CLASSICContestsHot Deals See All Hot Deals >>Latest Mountain Bike ArticlesMTBR on Facebook |


text:
More than 40,000 organizations already rely on ACTIVE as their software management provider, including:
"Online registration saves huge amounts of administrative time. We benefit from a huge savings on cost with registering online... We have about 800 kids in our league, which would equal 800 pieces of paperwork, 800 checks and 800 data points or more. All of the heavy lifting that would go into paper registration would be mind-boggling."
Bill Kennedy