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Nailtiques Formula 2 for Thin, Brittle Nails
Gwen W.No More Acrylic Nails!This is the best nail product I have ever used. I went from being a doubter to a believer! If your nails peel and are thin, this product is for you.posted Sep 17, 2013Link to this post
ML.A.Unbelieveable!All my life, I've had flimsy nail that broke and peeled. I have been using this product for over two years now. In all that time, no more need fro acrylics! If you like long, strong nails (that are NOT acrylic), this is the product for you. I get compliments on my nails ALL the time now.posted Sep 13, 2013Link to this post
LinaHairBlondeCurly HairColor Treated HairFine or Thin HairChemically Treated HairAmazingI've been using Nailtiques formula 2 since 1999. It's the absolute best product for nails I've ever tried. It makes them look and feel ten times better. I often get compliments on my nails and it makes my already naturally white tips look like I got a french manicure without wasting time at some salon. Best 2 minute solution around.posted Dec 11, 2012Link to this post
Gail G.Nailtiques 2 .. Best Thing Sincetim Gunn Who Is Also Fabulous!This product is so amazing .. been using it for years ... people often ask me if my nails are real ... and I'm proud to say .. they are b/c of Nailtiques 2 that I recommend to everyone! My manicurist recommended it many years ago. I go every other week for a mani, once a month for a pedi and use it exclusively on the odd weeks where I remove my polish from the mani. After my pedi, I put a coat on top .. and to refresh my mani, I apply it again and it looks like I just got my pedi. Great stuff!posted Apr 12, 2012Link to this post
MariannMAHairDark BrownNormal HairColor Treated HairLove This Helps My Nails Stay Strong!!!!Love this!!!! Helps my nails grow!posted Mar 20, 2012Link to this post
QuynhWorksIt works very well. Give it 6-8 weeks to get noticeable results. Apply it as directed (a layer a day and remove all each week).
I noticed my nails got a lot stronger and thicker. I'll switch to formula 1 now since i recently broke one and it hurt like a mother (breaking thick nails hurt a lot more than breaking thin nails) so maybe more flexible nails would help.posted Oct 27, 2011Link to this post -
Tiara D.United StatesNailtiques Formula 2 ReviewOverall I really liked this product. The only con is the price. For further detail and before and after pictures see video below.posted Jun 17, 2011Link to this post
Tiara D.United StatesNailtiques Formula 2 ReviewOverall I like Nailtiques Formula 2. The only con is the price. For further detail and before and after pictures click the video link below. ~Tiara Deanposted Jun 17, 2011Link to this post
MoLos AngelesWorth Every PennySure Nailtiques costs more than drugstore stuff or even some other products you can get at the beauty supply store. But Nailtiques Formula 2 really works and it works really great! It's got protein and polymers that makes it strong. And it drys really fast. As soon as I'm done painting one hand, the other is already dry.
To strengthen and fortify nails, put on two to three coats. It goes on clear. I don't have weak or thin nails but because I like to work in my garden, cook, bake, take care of my many pets, my hands are exposed to water a lot. And it makes my nails peel. For this purpose, I use Nailtiques to seal my nails on a regular basis.
As a base coat for manicures, put on one coat, let it dry and apply one to two coats of color. I think Nailtiques bonds to clean nails better than color and using it as a base coat keeps polish on longer. Also, I like that it prevents my nails from yellowing better than anything else I've tried. Even with the deepest burgundy colors, the yellowing of my nails is minimal if any. To finish your mani, seal the whole thing with a hard durable topcoat.
NOTE: If you really want your color to really last the test of time, put one more thin coat of Formula 2 on top of the color after the color dries. Give it a minute to dry and follow with a super hard top coat. Make sure you let every layer dry adequately before applying the next layer so that you don't get those annoying bubbles!posted Feb 1, 2011Link to this post -
MariaMarylandOne Of My Best Beauty Products Ever!My nails were literally falling apart for several months - breaking, peeling - because of stress (was loosing lot of hair as well). I started using Nailtiques formula 2 as they say to do: every day over that of the previous day etc for one week, remove and start over. I did not apply nail polish for two-three weeks. My nails were SO better after just two weeks. I couldn't believe it. After these 2-3 weeks, I continued using formula 2 under my nail polish base + nail polish. My nail are not as strong as they used to be (they probably never will), but they do not peel and do not break and look good. Because the hair loss continued, I also started taking supplements, but when I did I had already been using Nailitiques formula 2 for one month and my nails had already improved as described. Thanks for a good product!posted Jan 9, 2011Link to this post
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The Last Days Of American Crime #2
Created & Written by: Rick Remender
Illustrated by: Greg Tocchini
Lettering by: Rus Wooton
In order to pull of the heist of the century, Graham recruits veteran safe cracker Kevin Cash and his girlfriend Shelby, the computer hacker. Unfortunately for Kevin, Shelby has another idea in mind for Graham, seducing him... Leaving Kevin and Shelby to deal with their own set of problems. Meanwhile, left-for-dead Mexican gangster Enrique is looking for revenge. Along with two mysterious cops who are following the team's every move, Enrique kidnaps Shelby for ransom. Can Graham rescue her before time runs out?
Price: $4.99
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subset: commoncrawl


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This item is from the Fall 2004 season and might not be available anymore. (View current season)
Brown Gum Gold
Suede / Leather
- Random éS team rider tongue graphic
- Perforated tongue for breathability
- Double padded tongue and collar for comfort
- Elastic tongue-centering straps
- Full-length EVA midsole with cut-outs
- STI Foam™ level 1 footbed cushioning system
- 400 NBS stitched gum rubber outsole
- Outsole flex grooves for increased grip
- Sizes: 5-14
Foam Lite
Foam Lite insoles are tuned for maximum comfort and are formulated with a breathable moisture wicking material called Ortholite. This durable lasting foam stays squishy for a long time for superior comfort. The insoles also incorporate recycled rubber to make them more eco friendly.


text:
VOD is an uncommon but serious condition in the horse. Although early diagnosis is critical to treatment, diagnosis could be confounded by the highly variable and nonspecific signs of the disease.
To continue reading this article, become a member of TheHorse.com.
It's FREE and you'll get full access to more than 20,000 articles, video, free reports & more.


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Ah, now I get it. You're trolling. You had me there, pal.
forgiveness? i bow to your superior knowledge and intellect... oh wait no
IT WORKS AMAZINGLY WELL WITH X11!! and if you're stupid enough to be running a compositing window manager with a fancy DE and then encounter problems such as games failing and power consumption you can always quit said desktop env and run xinit ut2004 (for eg)
Ah, now I get it. You're trolling. You had me there, pal.
Hm, this is a tough one: why isn't an OS designed for servers able to beat Windows at its own game? Too complicated, I can't figure it out.
PS: If you whine about the performance in games compared to windows, try a video card from nvidia
I have always found that native games work very well under linux. For stuff in wine it is a mixed bag; some works better, some works worse, and some works not at all. My performane in windows also definately isn't 150% my linux performance (unless you compare the open drivers on linux with the closed windows drivers, then the performance on linux is terrible.)
why you say that developing a game is easier on windows ? that its glitch free ? that linux/x11 dosen't support direct rendering ?
wine bugzilla has bugs marked something like "needed cuz of a dirty hack on windows" and dirty hacks can get you some extra fps(a platform independent hack woud be Fast inverse square root, and platform dependant woud be like in what order to send vertices and how to make the gfx card swallow it faster)
problem is games are made for windows
its not really a problem since over 70% of gamers use windows and i doubt many of them know how anything works on their computer so games are made for windows for a simple reason to sell better(port to linux takes dev time that is money, and trust me they calculate with cold blood is it worth it)
oh, and only nvidia gets as much if not more fps on linux
i got 2 games that run better on linux on my rig, warcraft tft and xonotic that is linux native
PS having an opengl accelerated desktop is mostly rly bad for other opengl aps cuz of interference and as there is many backends for accelerating desktop it woud be hell to make a native game that cooperates with them(or making them cooperate with it)
one of the worst as i see in the phoronix benchmarks is unity, and my common sense tells me no DM shud use more then 100-200mb(remember "huge" file/page/stuff in computer terms is 4mb, enlightenment that im using right now with all its bling(xcept compiz, which is some 10mb in ram) uses 37mb on a 64bit sistem + X 27mb.
And that's relative as X adapts its caches (i guess enlightenment too)
Last edited by gens; 08-22-2012 at 12:48 PM.
The default desktop environment on Ubuntu (Unity) has a problem that causes the framerate to drop in games (bug #988079). You might want to try starting "Ubuntu Classic (No effects)" or Unity 2D instead for gaming.
Unfortunately third party development for Linux is difficult due to a lack of stable API's. There are often incompatibilities between different Linux distributions, and between different versions of the same distribution - even if they are released just a few months apart. There is also a lack of a standardized way of distributing software that works across different Linux distributions. If there isn't a package for your specific distribution you'll usually end up with a .tar.gz and a howto. That's why you often need to use various hacks and tricks to get third party software working. Hopefully the situation will improve since both Ubuntu and Gnome is aiming for API stability now.
Last edited by nej_simon; 08-22-2012 at 12:50 PM.


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4-0 in August
On Baseball: Fisher Cats' McGuire responding nicely
The New Hampshire Fisher Cats starting pitcher struggled to a 5-15 record with an ERA of 5.88 in his first full season of Double-A baseball a year ago.
"Last year was tough as everybody knows. (This year) was a chance to come in fresh for a new season and build off the way last year finished," McGuire said prior to Thursday night's regular-season home finale against Portland. "This year, all year long it's been finding a comfort zone over the course of my 25, 26 starts."
"It's been going well. It's been a culmination of everything we've worked on all year long," McGuire said. "It's been a nice stretch to finish up the year."
"He's gotten ahead (in the count) better. He's pitched down in the zone better and he's mixed his pitches very well," Allenson said. "It's one those things where you mix it up, not always throwing a fastball on a fastball count, good things happen and that's what he's done."
"I thought it was a really good year. I know numbers lie a lot," he said. "There are times this year where they weren't where I wanted them to be, but all in all, it's been a good year."
"That was the biggest learning part of last year. It was trying to find consistency within an outing," McGuire said. "This year, whether I have five good innings and one bad pitch in the sixth or whatever, just keep going. If you make one bad pitch in a start and it happens to beat you then there's not a whole lot you can do about it. It's learning to understand the game and learning to accept the process and keep building."
In other moves, catcher Jack Murphy was called up to Triple-A Buffalo and a pair of Single-A players from Dunedin (catcher Chris Schaeffer and outfielder Jonathan Jones) were shipped to New Hampshire. Jones was in the starting lineup Thursday night.


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Prep time: about 20 minutes Ingredients:
Serves: 2 Serving size: 3 or 4 medium pancakes Nutritional analysis (per serving): 333 calories 11 g protein 9 g fat 52 g carbohydrate 3 g fiber 108 mg cholesterol 915 mg sodium 270 mg calcium 2.8 mg iron
Note: Nutritional analysis may vary depending on ingredient brands used.
Variations and suggestions: Eat your pancakes with powdered sugar, cinnamon, maple syrup, jelly, or fruit on top.
Reviewed by: Allison Brinkley, RD, LD/N


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Summary: Tyrosine phosphatase family
Pfam includes annotations and additional family information from a range of different sources. These sources can be accessed via the tabs below.
This is the Wikipedia entry entitled "Protein tyrosine phosphatase". More...
Protein tyrosine phosphatase Edit Wikipedia article
Protein-tyrosine-phosphatase | |||||||||
Identifiers | |||||||||
EC number | 188.8.131.52 | ||||||||
CAS number | 79747-53-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Protein tyrosine phosphatases (EC 22.214.171.124, PTPs, phosphotyrosine phosphatase, phosphoprotein phosphatase (phosphotyrosine), phosphotyrosine histone phosphatase, protein phosphotyrosine phosphatase, tyrosylprotein phosphatase, phosphotyrosine protein phosphatase, phosphotyrosylprotein phosphatase, tyrosine O-phosphate phosphatase, PPT-phosphatase, PTPase, [phosphotyrosine]protein phosphatase, PTP-phosphatase) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Protein tyrosine (pTyr) phosphorylation is a common post-translational modification that can create novel recognition motifs for protein interactions and cellular localization, affect protein stability, and regulate enzyme activity. As a consequence, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases (PTPase; EC 188.8.131.52) catalyse the removal of a phosphate group attached to a tyrosine residue, using a cysteinyl-phosphate enzyme intermediate. These enzymes are key regulatory components in signal transduction pathways (such as the MAP kinase pathway) and cell cycle control, and are important in the control of cell growth, proliferation, differentiation and transformation.[1][2]
Together with tyrosine kinases, PTPs regulate the phosphorylation state of many important signalling molecules, such as the MAP kinase family. PTPs are increasingly viewed as integral components of signal transduction cascades, despite less study and understanding compared to tyrosine kinases.
PTPs have been implicated in regulation of many cellular processes, including, but not limited to:
By mechanism
The PTP superfamily can be divided into four subfamilies.[3][4]
Links to all 107 members of the protein tyrosine phosphatase family can be found in the template at the bottom of this article.
Class I
The class I PTPs, are the largest group of PTPs with 99 members, which can be further subdivided into
- 38 classical PTPs
- 21 receptor tyrosine phosphatase
- 17 nonreceptor-type PTPs
- 61 VH-1-like or dual-specific phosphatases (DSPs)
- 11 MAPK phosphatases (MPKs)
- 3 Slingshots
- 3 PRLs
- 4 CDC14s
- 19 atypical DSPs
- 5 Phosphatase and tensin homologs (PTENs)
- 16 Myotubularins
Dual-specificity phosphatases (dTyr and dSer/dThr) dual-specificity protein-tyrosine phosphatases. Ser/Thr and Tyr dual-specificity phosphatases are a group of enzymes with both Ser/Thr (EC 126.96.36.199) and tyrosine-specific protein phosphatase (EC 18.104.22.168) activity able to remove the serine/threonine or the tyrosine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase. Dual-specificity protein phosphatases (DSPs) regulate mitogenic signal transduction and control the cell cycle.
LEOPARD syndrome, Noonan syndrome, and Metachondromatosis are associated with PTPN11.
Class II
LMW (low-molecular-weight) phosphatases, or acid phosphatases, act on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.[5][6]
The class II PTPs contain only one member, low-molecular-weight phosphotyrosine phosphatase (LMPTP).
Class III
Cdc25 phosphatases (dTyr and/or dThr)
The Class III PTPs contains three members, CDC25 A, B, and C
Class IV
pTyr-specific phosphatases
The class IV PTPs contains four members, Eya1-4.
This class is believed to have evolved separately from the other three.[7]
By location
Based on their cellular localization, PTPases are also classified as:
- Receptor-like, which are transmembrane receptors that contain PTPase domains.[8] In terms of structure, all known receptor PTPases are made up of a variable-length extracellular domain, followed by a transmembrane region and a C-terminal catalytic cytoplasmic domain. Some of the receptor PTPases contain fibronectin type III (FN-III) repeats, immunoglobulin-like domains, MAM domains, or carbonic anhydrase-like domains in their extracellular region. In general, the cytoplasmic region contains two copies of the PTPase domain. The first seems to have enzymatic activity, whereas the second is inactive.
- Non-receptor (intracellular) PTPases[9]
Common elements
All PTPases carry the highly conserved active site motif C(X)5R (PTP signature motif), employ a common catalytic mechanism, and possess a similar core structure made of a central parallel beta-sheet with flanking alpha-helices containing a beta-loop-alpha-loop that encompasses the PTP signature motif.[10] Functional diversity between PTPases is endowed by regulatory domains and subunits.
Expression pattern
Individual PTPs may be expressed by all cell types, or their expression may be strictly tissue-specific. Most cells express 30% to 60% of all the PTPs, however hematopoietic and neuronal cells express a higher number of PTPs in comparison to other cell types. T cells and B cells of hematopoietic origin express around 60 to 70 different PTPs. The expression of several PTPS is restricted to hematopoietic cells, for example, LYP, SHP1, CD45, and HePTP.[15]
- ^ Dixon JE, Denu JM (1998). "Protein tyrosine phosphatases: mechanisms of catalysis and regulation". Curr Opin Chem Biol 2 (5): –. PMID 9818190.
- ^ Paul S, Lombroso PJ (2003). "Receptor and nonreceptor protein tyrosine phosphatases in the nervous system". Cell. Mol. Life Sci. 60 (11): –. doi:10.1007/s00018-003-3123-7. PMID 14625689.
- ^ Sun JP, Zhang ZY, Wang WQ (2003). "An overview of the protein tyrosine phosphatase superfamily". Curr Top Med Chem 3 (7): –. PMID 12678841.
- ^ Alonso A, Sasin J, et al. (2004). "Protein tyrosine phosphatases in the human genome". Cell 117 (6): 699–711. doi:10.1016/j.cell.2004.05.018. PMID 15186772.
- ^ Wo YY, Shabanowitz J, Hunt DF, Davis JP, Mitchell GL, Van Etten RL, McCormack AL (1992). "Sequencing, cloning, and expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatase". J. Biol. Chem. 267 (15): 10856–10865. PMID 1587862.
- ^ Shekels LL, Smith AJ, Bernlohr DA, Van Etten RL (1992). "Identification of the adipocyte acid phosphatase as a PAO-sensitive tyrosyl phosphatase". Protein Sci. 1 (6): 710–721. doi:10.1002/pro.5560010603. PMC 2142247. PMID 1304913.
- ^ William C. Plaxton; Michael T. McManus (2006). Control of primary metabolism in plants. Wiley-Blackwell. pp. 130–. ISBN 978-1-4051-3096-7. Retrieved 12 December 2010.
- ^ Knapp S, Longman E, Debreczeni JE, Eswaran J, Barr AJ (2006). "The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1". Protein Sci. 15 (6): –. doi:10.1110/ps.062128706. PMC 2242534. PMID 16672235.
- ^ Perrimon N, Johnson MR, Perkins LA, Melnick MB (1996). "The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila". Dev. Biol. 180 (1): –. doi:10.1006/dbio.1996.0285. PMID 8948575.
- ^ Barford D, Das AK, Egloff MP (1998). "The structure and mechanism of protein phosphatase s: insights into catalysis and regulation". Annu. Rev. Biophys. Biomol. Struct. 27 (1): –. doi:10.1146/annurev.biophys.27.1.133. PMID 9646865.
- ^ Su XD, Taddei N, Stefani M, Ramponi G, Nordlund P (August 1994). "The crystal structure of a low-molecular-weight phosphotyrosine protein phosphatase". Nature 370 (6490): 575–8. doi:10.1038/370575a0. PMID 8052313.
- ^ Stuckey JA, Schubert HL, Fauman EB, Zhang ZY, Dixon JE, Saper MA (August 1994). "Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate". Nature 370 (6490): 571–5. doi:10.1038/370571a0. PMID 8052312.
- ^ Yuvaniyama J, Denu JM, Dixon JE, Saper MA (May 1996). "Crystal structure of the dual specificity protein phosphatase VHR". Science 272 (5266): 1328–31. doi:10.1126/science.272.5266.1328. PMID 8650541.
- ^ Aceti DJ, Bitto E, Yakunin AF, et al. (October 2008). "Structural and functional characterization of a novel phosphatase from the Arabidopsis thaliana gene locus At1g05000". Proteins 73 (1): 241–53. doi:10.1002/prot.22041. PMID 18433060.
- ^ Mustelin T, Vang T and Bottini N. (2005). "Protein tyrosine phosphatases and the immune response". Nat. Rev. Immunol. 5 (1): 43–57. doi:10.1038/nri1530. PMID 15630428.
External links
- PTP Summary and Relevant Publications at Monash University
- Protein-Tyrosine-Phosphatase at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the public domain Pfam and InterPro IPR000106
This page is based on a Wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.
This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.
Tyrosine phosphatase family Provide feedback
This family is closely related to the PF00102 and PF00782 families.
Internal database links
SCOOP: | PTPlike_phytase |
Similarity to PfamA using HHSearch: | DSPc Y_phosphatase Y_phosphatase2 DUF442 PTPlike_phytase |
External database links
Pseudofam: | PF13350 |
SYSTERS: | Y_phosphatase3 |
This tab holds annotation information from the InterPro database.
No InterPro data for this Pfam family.
Domain organisation
Below is a listing of the unique domain organisations or architectures in which this domain is found. More...
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Pfam Clan
This family is a member of clan Phosphatase (CL0031), which has the following description:
This family includes tyrosine and dual specificity phosphatase enzymes.
The clan contains the following 9 members:
CDKN3 DSPc DUF442 Init_tRNA_PT Myotub-related PTPlike_phytase Y_phosphatase Y_phosphatase2 Y_phosphatase3Alignments
We store a range of different sequence alignments for families. As well as the seed alignment from which the family is built, we provide the full alignment, generated by searching the sequence database using the family HMM. We also generate alignments using four representative proteomes (RP) sets, the NCBI sequence database, and our metagenomics sequence database. More...
View options
We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.
Seed (403) |
Full (1860) |
Representative proteomes | NCBI (2255) |
Meta (428) |
Jalview | ||||||||
PP/heatmap | 1 | |||||||
Pfam viewer |
1Cannot generate PP/Heatmap alignments for seeds; no PP data available
Key: available, not generated, — not available.
Format an alignment
Download options
We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.
Seed (403) |
Full (1860) |
Representative proteomes | NCBI (2255) |
Meta (428) |
Raw Stockholm | ||||||||
Gzipped |
You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.
External links
MyHits provides a collection of tools to handle multiple sequence alignments. For example, one can refine a seed alignment (sequence addition or removal, re-alignment or manual edition) and then search databases for remote homologs using HMMER3.
HMM logo
HMM logos is one way of visualising profile HMMs. Logos provide a quick overview of the properties of an HMM in a graphical form. You can see a more detailed description of HMM logos and find out how you can interpret them here. More...
This page displays the phylogenetic tree for this family's seed alignment. We use FastTree to calculate neighbour join trees with a local bootstrap based on 100 resamples (shown next to the tree nodes). FastTree calculates approximately-maximum-likelihood phylogenetic trees from our seed alignment.
Note: You can also download the data file for the tree.
Curation and family details
This section shows the detailed information about the Pfam family. You can see the definitions of many of the terms in this section in the glossary and a fuller explanation of the scoring system that we use in the scores section of the help pages.
Seed source: | Jackhmmer:C2D3Y7 |
Previous IDs: | none |
Type: | Family |
Author: | Coggill P |
Number in seed: | 403 |
Number in full: | 1860 |
Average length of the domain: | 158.20 aa |
Average identity of full alignment: | 28 % |
Average coverage of the sequence by the domain: | 56.25 % |
HMM information
HMM build commands: |
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
Model details: |
Model length: | 164 | ||||||||||||
Family (HMM) version: | 1 | ||||||||||||
Download: | download the raw HMM for this family |
Species distribution
Sunburst controls
ShowThis visualisation provides a simple graphical representation of the distribution of this family across species. You can find the original interactive tree in the adjacent tab. More...
Tree controls
HideThe tree shows the occurrence of this domain across different species. More...
Please note: for large trees this can take some time. While the tree is loading, you can safely switch away from this tab but if you browse away from the family page entirely, the tree will not be loaded.
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Y_phosphatase3 domain has been found. There are 3 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
Loading structure mapping...


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Saint Xavier University wins Mercy Grant
Saint Xavier will use grant to create referral network for the uninsured
Chicago (April 20, 2007) – The Saint Xavier University Health Center will be better able to provide quality health care for uninsured patients thanks to a $20,000 grant from the Sisters of Mercy, Regional Community of Chicago. The grant will allow Saint Xavier to build a specialist referral network for uninsured clients through partnerships with outside health providers and agencies. "This effort will fill a service gap for the uninsured and enable the Health Center to provide best practice specialty care to more clients," said SXU School of Nursing Dean Anne Bavier, Ph.D. "This further enhances our mission of service at Saint Xavier." Saint Xavier University Health Center, a nurse practitioner-managed primary care facility, accommodated 4,500 patient visits last year. More than 50 percent of the patients seen were community members from outside the University, a significant number either uninsured or underinsured. "This poses a challenge for us as providers when patients present with a health condition that requires further evaluation by a medical specialist or needs specialized diagnostic testing," said Monica Ryan, assistant professor of nursing and director of the Health Center. "Establishing relationships with agencies or medical specialists in the community will support collaboration and facilitate the referral process. This outcome will enable patients to receive this much needed care and continue their follow-up at the Health Center." The Sisters of Mercy grant comes through the Agatha O'Brien Ministry Fund, named in honor of Sister Agatha O'Brien (1822-1854), superior of the first Sisters of Mercy who arrived in Chicago in 1846. During the past 15 years, the Sisters of Mercy have awarded 250 grants to various ministries in which its sisters and associates bring Mercy to the world. The funds help local efforts to serve poor or suffering people, to support "innovative ministries" that respond to contemporary human needs, and to respond to the needs of women, children and multicultural communities. Grant recipients have included literacy programs, inner-city schools, family centers, prison ministry, housing development, retirement centers, leadership training, women's shelters, spiritual counseling and more. The Sisters of Mercy is a global congregation of Catholic women who value prayer, life in community and compassionate ministry. Sisters, associates, companions, and volunteers serve people who are poor, sick and uneducated, with a special concern for women and children. Since their founding in 1831, the Sisters of Mercy have used their deep knowledge and expertise to initiate systems for healthcare, education, housing, advocacy and social services around the world. FOR MORE INFORMATION: Contact Joe Moore (773) 298-3937 or firstname.lastname@example.com


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Our 2006 Trip to Newfoundland George Street FestivalCeltic Connection
Click on the photo above for a larger version.
This photo was taken by Don Shorock at 9:30 PM NDT on Tuesday, the 1st of August, 2006 We had seen Celtic Connection at the Shamrock Festival on our first visit to Newfoundland. We loved their music and wanted to see them again. However, as so often happens when we are in St. John's, there were two things we wanted to do at the same time. We also wanted to attend the SJFAC's Session Night at the Masonic Hall. The two events were only a few blocks apart, so it seemed possible to take in a bit of both, so that's what we did although it was a shame to walk out on such a fine performance. We did stay long enough to hear one of our favourite songs in their repertoire, Walk in the Irish Rain. This song sounds like a traditional Irish ballad (and occasionally gets identified as such), but it was actually written by a friend of ours, Steve Spurgin. Although many of his songs sound like traditional Irish ballads, Steve actually grew up in Texas and recently moved in Nevada. The photo above is 420x315 pixels. Clicking on it will bring you to a version that is 800x600. If you wish to print this photo, you probably want a higher resolution version. If you have high-speed internet, I can e-mail you a larger (2048x1536) version. To request one, e-mail me at firstname.lastname@example.com and specify photo #435 (P8016968.jpg). |


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Vandalia Golf & Country Club
Opened in 1916, this nine-hole course features 2,782 yards of golf from the longest tees, for a par of 35.
Staunton Country Club
This well-established, hilly nine-hole, semi-private course has many mature oaks, small greens and one water hole. The club also offers a swimming pool, tennis court and snack bar.
Colonial Golf Course
This public 18-hole, par 70 course is open year round, with rental clubs and carts, plus a snack bar.
Glik Park Complex
The Glik Complex features four baseball/softball diamonds, five soccer fields and two football fields. The park also has a basketball court, skate park, concession stand, and a 2.7-mile walking trail spread over 50 acres.
Korte Recreation Center
This great building, operated by the city of Highland, offers a cardio/weight room, indoor walking track, indoor aquatic center and full-size gymnasium. The gym can accommodate two basketball or volleyball courts.
Greenville College
Greenville College's H.J. Long Gymnasium, a 2,000-seat venue, houses the varsity volleyball and basketball programs, and is capable of being configured for two additional courts. The Crum Recreation Center features a fantastic gym setup, and can handle two basketball, tennis or volleyball courts.
Governors Run Golf and Country Club
This championship 18-hole course has 13 lakes scattered throughout the par 72 layout. It boasts five sets of tees to accommodate all skill levels on exquisitely manicured greens.
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So get this. Spent the entire weekend painting in no air conditioning 100 degree heat and by 5 pm tonight (Sunday) I needed a swim in the ocean soo insanely bad.
Round up my 2 kids and get to Long Branch and we're in the water when guards pull up about 6 pm and order everyone out of the water. No swimming after hours in response to recent drownings. I asked the guard, "So the ocean's closed?" "Yeah, pretty much," he said. You can now only swim between 10 am and 5 pm.
I was so friggin' livid on so many levels I can't even go into it. But I wonder what the legality of this is? Are other towns doing this now? There are drownings ever year. They never did this. There are fatal accidents on the highways every day. They don't close them. Seriously, I can't take it any more.


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Maholm will go for fourth win against Tigers
No longer preserving a scoreless-innings streak, Paul Maholm will focus on preventing a losing streak -- personally, and for his team -- when the Braves open a three-game Interleague series at Comerica Park on Friday night.
Maholm, who will oppose Detroit's Anibal Sanchez, began his season with 25 2/3 consecutive scoreless innings, the Majors' longest season-opening streak since 1966. That was snapped on Saturday, when he allowed three runs in the sixth against the Pirates and took the loss to drop to 3-1.
"I was going to give up a run," said Maholm, whose ERA rose to 1.03. "I'm not really worried about the streak. It was going to happen. I wish it would have happened in a game where we scored five, and I gave up three and we win."
The lefty is not a stranger to facing the Tigers from his days with the Pirates, having pitched against them in Interleague matchups each of the past three seasons and compiling a 2.60 ERA. But the Braves haven't played the Tigers since 2010 and have visited Detroit only once, in 2004.
Atlanta, which started 12-1, dropped five of eight games heading into Thursday's off-day, including a walk-off loss against the Rockies on Wednesday afternoon.
The Braves will have to contend with a familiar foe in Sanchez, who pitched in the NL East with the Marlins from 2006-12. The right-hander has a 5.42 ERA in 17 starts against the Braves, his highest against any club he's faced more than four times. Over the past two seasons, Atlanta has touched him up for a 9.33 ERA in four outings.
Sanchez (2-1, 1.75) has not allowed more than two earned runs in any of his four starts this season, but is coming off his first loss, Friday against the Angels. He surrendered a season-high 11 hits in 6 2/3 innings.
"We're going to play here, so we're still in the American League [rules]," Sanchez said. "It probably would be different if we had to play in the National League and I had to hit. It's going to be a normal day, so we have to prepare like we always do for any team.
"Right now, they've got three new guys. It seems like a new team right now, not the team that I've faced. It's a different Braves. They've got the Uptons. They've got [Chris] Johnson, [Juan] Francisco, [Jordan] Schafer. They've got a lot of new guys."
Braves: Healthy Freeman looks to reignite
• First baseman Freddie Freeman hit .412 with seven RBIs in five games before going on the disabled list with a strained right oblique. He returned for Tuesday's doubleheader and went 1-for-6 with three walks, then went 1-for-5 with an RBI double on Wednesday.
"I'm good -- everything felt great," Freeman said before Wednesday's game. "Obviously I wouldn't have come back if I wasn't. Usually you can't come back in two weeks, but I guess we got it under control real quick and I feel great."
• Third baseman Francisco went 2-for-4 on Wednesday, his fourth multi-hit game out of his last six. Over that span, he is 9-for-24 (.375) with three homers and six RBIs.
Tigers: Pitchers racking up punchouts
• Sanchez, with 24 strikeouts in 25 2/3 innings, isn't the only Detroit hurler making batters miss this season. The Tigers staff has 193 strikeouts, the most in April in club history since at least 1921.
• First baseman Prince Fielder batted .337 with a .438 on-base percentage at Comerica Park last season, compared to .291/.386 marks on the road. He's back to his raking ways in his home ballpark again this year. Through his first eight home games this season, Fielder is hitting .375 (9-for-24) with a .541 on-base percentage.
Worth noting
• This is the Tigers' first Interleague series of the year, while the Braves already went 1-1 against the Royals.
• The Tigers hold a 9-6 lead in the all-time series, which began in 1997.
• Fielder is 7-for-51 (.137) against Maholm, and his .337 OPS is his lowest against any pitcher he has faced at least 20 times. Maholm has struck out Fielder 15 times while holding him without an extra-base hit.
Andrew Simon is a contributor for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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The X-Culture Project Exposes Students to the Challenges and Best Practices of Cross-Cultural Collaboration
By Alex Stills | GLOBE CORRESPONDENT MAY 12, 2014
"It's Always Sunny in Philadelphia" star Charlie Day will put his illiterate, man-child character aside on Sunday as keynote speaker to more than 500 graduating seniors at Merrimack College. "I think people are going to be expecting me to be wildly funny, but I think I will probably speak more earnestly and directly from the heart, more about the reality of how I got where I got," he said. Day received a bachelor's degree in fine arts (perhaps the only one) at Merrimack in 1998. Read the full story on bostonglobe.com »
One prospective student's first-hand experience helped him choose Merrimack
Coke Exec Tells Students Liberal Arts Is Best Preparation for Business Careers


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Showing stories 1 of 1
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"If Seth had waiver services, everything would change. He would have something to look forward to and something to do. "


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Justice Scalia is not "substituting his views for those of legislators." Despite the distorted view of the author he is indeed letting the people's elected representatives handle the matter of racial discrimination and voting. But he says the power lies with the elected representatives of the States not of the Federal government.
I've never seen such an egregious example of anti-constitutional speech to encourage yet more Federal power building. The US constitution says that Federal rights trump States rights only in the enumerated powers. Can the author explain where the Federal authority he claims is listed in them?


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Top Definition
A small town outside of Quito, Ecuador, where many painters and artists live. It has beautiful landscapes and very friendly people.
I used to live in Alangasí. It is a rather peaceful place. Great place to live if you like reading poetry and relaxing.
από Raúl Soleimani
23 Ιανουάριος 2009


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The art of being a workaholic without being a workaholic
Short-handed Cavaliers in tough spot heading into Game 2 against Chicago
Browns GM Ray Farmer's curious draft blueprint raises a few questions
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Shale rock could put U.S. on road to energy independence
Blog Entry:
December 11, 2012 6:00 AM | Author: SCOTT SUTTELL
that the success of American drillers in coaxing fossil fuels from shale rock "has the potential to boost production so much that it may deny OPEC the power to set global oil and gasoline prices," according to findings by an intelligence advisory panel.
The report from the
National Intelligence Council
found that rising domestic production from hydraulic fracturing is expanding U.S. supplies, which would shift the balance of power in global energy markets, Bloomberg says.
"As the U.S. adds supply, the Organization of Petroleum Exporting Countries' influence over prices would wane," according to the report. "In a tectonic shift, energy independence is not unrealistic for the U.S. in as short a period as 10-20 years."
Bloomberg reports that the intelligence analysis finds that concern about the environmental impacts is the "greatest obstacle" to fracking.
"A tighter regulatory environment, which is beginning to happen in some U.S. states, could also close loopholes and reassure public safety," the report states.
The news service reports that the 12 OPEC nations "produce more than 40 percent of the world's oil, a volume that gives its production decisions influence over the crude prices, the single largest contributor to gasoline costs."
But additional production here "could significantly cut oil prices, increase U.S. economic activity by more than 2 percent and add 3 million jobs by 2030," Bloomberg reports.
"Total global crude output would exceed demand by more than 8 million barrels a day, at which point OPEC would lose price control and crude oil prices would collapse," according to the report.
Coal's global appeal
A surprise side effect of the shale gas boom in Ohio and elsewhere is a
coal boom overseas
So writes Forbes.com, in a piece based on a soon-to-be-released report from the
International Energy Agency
, or IEA.
"America is shuttering coal plants but not coal mines, and coal unwanted at home is finding its place overseas," according to the website. (The post includes a photo of coal mined in Ohio that it now says "is more likely to be burned in Europe or China.)
In the report, the IEA is expected to announce that Europe "has shifted from clean natural gas to dirtier coal as U.S. coal, displaced at home by shale gas, floods the European energy market," Forbes.com reports.
"Low gas prices associated with the shale gas revolution caused a marked decrease in coal use in the United States, the world's second-largest consumer," according to the IEA. "This led U.S. thermal coal producers to seek other markets, which resulted in an oversupply of coal in Europe and a significant gas-to-coal switch."
In addition, Forbes.com says, the IEA's Mid-Term Coal Report will forecast "increased use of coal in China, now the world's largest coal importer, and it will project even greater demand for coal in India."
Gas pains
Ohio Supreme Court
has ruled that money collected from a tax on businesses selling fuel must be used toward highway-related programs, according to
this Associated Press story
In essence, the court ruled that the tax is wrongly diverting about $140 million annually from fuel sales to nonroadwork accounts for schools and cities, the AP says. You can read the 20-page opinion
Columbus Business First
that construction companies and county engineers were among those suing over the state's use of the Commercial Activity Tax for other purposes. (The tax applies only to companies selling fuel, not the fuel itself.)
In a 6-1 decision, the court said the CAT still must be applied to companies that make money selling fuel, but it can't be diverted into the state fund that pays for everything from schools to health care for the poor, the AP reports.
The Ohio Constitution "explicitly prohibits the expenditure of revenue derived from excises on motor-vehicle fuel for any purpose other than highway purposes," Justice Robert Cupp wrote for the majority.
The office of Gov. John Kasich, which must produce a balanced two-year budget early next year, is reviewing the decision, spokesman Rob Nichols tells the AP.
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7th. But that was only because he lost A LOT of points due to combination rules.. Oda missed the previous season due to some personal issues, and I think last season he was just getting back into the swing of things competition wise (he only had one GP event) He seemed to be getting better at worlds and WTT. He beat Chan there, but his programs were crap last year.
He needs to really kick butt though this season if he wants the judges to be willing to give him the OGM. I think if he beats Lyseck here. Wins GPF, and starts landing quads, Oda will be making a strong case for himself. His long program is so strong, and if he adds a quad to that, it will be the whole package that has been missing for awhile.
I see there has been some discussion about Evan's costume, so maybe the question was addressed already. But since I really want to know, I will ask anyway: why is the costume black? I thought he was performing the firebird, right? And the firebird is supposed to be colorful, like Yukari Nakano's version. Was he trying to portray some other character?
It's not a sarcastic question. I thought his program was fine, but I just could not help but keep wondering why the costume is black when I watched it. BTW, the Chinese announcers seemed to like this program, and the female announcer even said this program really fits Evan Lysacek's character/persona--- I'm not sure I understand what she meant (my guess is that she thought this program is passionate, and passion suits Lysacek). So, yeah, I think I need to understand why it is black first.
A little known fact but Evan is a huge fan of Johnny Cash, "The Man in Black."
(Not to be confused with the motion picture "Men in Black," parts 1 & 2)
Watch for Evan's new exhibition music this year, the old Johnny Cash standard "A Boy Named Sue."
Weir is so jealous about this he almost quit skating - again.
Last edited by janetfan; 10-30-2009 at 07:46 PM.
I think he is Prince Ivan.
His many great Euro fans might think he is the Prince of Darkness
Last edited by janetfan; 10-30-2009 at 08:14 PM.
You cannot compare Oda's score at TEB with Plushenko's at RC. Different judges give different scores, of course. Remember 2009 worlds? Joubert was still marked first with a mistaken SP, ahead of Canadian Chan, the judges' new favorite. I think quads really count when it comes to big competitions, like Winter Olympics.
Last edited by wonderland; 10-30-2009 at 09:29 PM.


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Mark Aivazian 5pts Next year you can witness my truck in the throwdown. Then you will have seen the perfect truck. Not kidding either :)
Luis Rodriguez 5pts Syclone was made a limited amount because the company from louisiana that made them for gm went out of business
Billy Underwood 5pts Why would you even have this event without a Lightning? None of the trucks I seen in the event would have a chance against it. Oh, maybe that's why.
Danny Alvarado 5pts Syclone only made so many because it was meant to be a limited edition have not found a truck to beat mine yet ....
Yancey Simmons 5pts If syclones were the best why did they make only 2995? They're junk! Ram all the way
Andrew O'Brate 5pts my old single cab joe Gibbs chevy built supercharged lowered with bear brakes and custom suspension


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The Sons of God
In the twentieth century, the German biblical scholar Rudolf Bultmann gave a massive critique of the Scriptures, arguing that the Bible is filled with mythological references that must be removed if it is to have any significant application to our …Read More
Exegesis has Consequences
Ideas have consequences. Since the dawn of Western philosophy, we have witnessed the good, the bad, and the ugly of this axiom. From the influence of John Locke upon the founders of America, to the disastrous results of the influence …Read More
A Sound Principle
Good exegesis will tell us that bad conclusions do not burst forth de novo from bad exegesis. It is valuable, important, even potent for us to have a good grasp of sound hermeneutical principles, to be on our guard against …Read More
Commentaries as a Ministry
I love writing commentaries. I feel as if it is what God made me to do. I have written around twelve of them, ranging from thirty-page overviews to one-thousand-page detailed expositions. I just finished one and will start another in …Read More
The Importance of Sound Exegesis
A Bible scholar walks into a friend's kitchen and sees a magnet fixing a diet plan to the refrigerator door. It reads, "'For I know the plans I have for you,' declares the Lord, 'plans to prosper you . . …Read More
Grammatical Fallacies
God's Word comes to us in words. These words are human words: chosen by particular human beings in particular circumstances to communicate a particular message. Of course, the words of Scripture are also divine words. Each one of them is …Read More
Logical Fallacies
Logic (from the Greek word logos, "reason") is the "science that deals with the principles and criteria of validity of inference and demonstration, the science of the formal principles of reasoning" (Merriam-Webster). While theology, as the study of God, transcends …Read More
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The incredible imaginative power of the human mind connects us. If I mention standing ankle deep in the ocean, many of you can picture this image (and maybe feel the dizziness as you watch the water rush past your feet …Read More
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"New and improved!" Advertisers emblazon this slogan upon countless products on the shelves of your local grocery store. If you are convinced the product is better, they reason, you will probably want to buy it. After all, who wants the …Read More
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I'm surprised the article didn't mention what Linus said.
Yes, clearly..... I don't want to take anything away from the work that the developers mentioned in the article are doing. There's a legitimate case to be made for some of this infrastructure to exist before it could be built upon. But how could "Nvidia Optimus" now not be mentioned without also mentioning the name of Linus Torvalds?
It's the elephant in the living room.


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It Works, BUT... - 2/15/2015 5:54:49 PM Make sure you use it on clean, dry skin. Use it before you use any other product, after you clean your face. Then, LET it dry until you can feel the tightness, then... look in the mirror. It works.Love It - 2/9/2015 6:38:29 AM I received this as a sample and am placing my order now for a tube. I've been looking for a BB Cream that was more than just a moisturizing sunscreen. This provides real coverage,but not heavy, similar to a sheer foundation. It feels silky when it goes on and I don't even need powder to set it.Amazing BB Cream! - 2/7/2015 3:08:33 PM I just received a free sample with my Skinstore order. I'm nearing 60 and still have oily skin, so I take good care of my pores and have a regular regimen. This product has superior and non-oily coverage! WOW. This is going to be an everyday use product. My skin feels great and looks great!I love this eye cream - 1/16/2015 10:51:42 AM I have been using this eye cream for over a year. It is thick but spreads easy. I personal like an eye cream that is a little thicker because I feel it works better. When I say thick I don't mean like paste, it is easy to apply and makes skin look and feel smooth.Advanced Under Eye Dried out! - 9/7/2014 7:36:22 PM The advanced under eye treatment mini in this set is completely dried out. Other website reviews show this same issue. Beware of this!Delighted with this product - 4/26/2014 6:10:23 PM After using another product for several years I needed to move on to something else. I chose Hydroxatone and I'm very satisfied with the results. It's light , creamy and absorbs quickly . It leaves a nice silky feel to the skin and makeup smooths out more evenly. I see a definite difference in my skin !Only BB I'll Ever Use - 3/25/2014 10:32:17 AM I have had such bad luck with BB creams. I want something to wear to the gym that covers my keratosis pilaris, but looks natural and doesn't feel heavy. So many BB creams either don't cover well or turn my face orange. This one is PERFECT. It's a bit pricy, but it covers the redness and blends into my natural skin tone. None of my friends at the gym can tell I'm wearing makeup, which is a huge win! :)Best sample ever - 3/12/2014 9:05:02 AM I received this sample with a separate purchase and ill definitely be ordering it. I had a breakout from going to the gym and not immediately being able to shower. When I got home I decided to give it a try. I'm do glad I did. My skin will be great for spring break now. *combination skin. Med completion.Waste of money - 1/31/2014 8:49:46 AM this stuff is like putting on old fashioned "cold cream" , doesn't absorb well & doesn't smell goodlove this product - 11/25/2013 2:18:13 AM This is my favorite toner. It doesn't irritate my skin and seems to make my other products work better. -
Learn More About Hydroxatone
Aging is inevitable, but its most ravaging effects on the skin can often be mitigated with the right products and the right skincare practice. That's the guiding mission of the Hydroxatone brand, which offers formulations that tackle common aging symptoms on both the face and the rest of the body.
There are two broad categories of aging: intrinsic and extrinsic. Intrinsic aging refers to the genetically dictated part of the process, the onset of traits such as skin dryness and degraded elasticity that proceeds on a different timetable for everybody. Extrinsic aging is sometimes called "premature aging," and stems from our own lifestyle choices and our exposure to the environment. Causes of extrinsic aging are diverse, running the gamut from a poorly balanced diet heavy on refined carbohydrates to unprotected tanning from natural sunlight or an artificial machine.
To combat wrinkles, age spots, sagging folds, raccoon eyes, and other regular dermatological manifestations of aging, the Hydroxatone line employs advanced formulations integrating skin-boosting ingredients. Three of the major ones are Matrixyl 3000, Argireline, and Hyaluronic Acid. The first two are peptides that promote collagen production, which can diminish the appearance of creases and wrinkles. Hyaluronic Acid, meanwhile, is a significant hydrator--capable of holding some 1,000 times its weight in water--and helps improve your skin's softness and smoothness. Whether it's the corners of the eyes or the décolleté, Hydroxatone has the tools for restoring some texture and vibrancy to age-pummeled skin.


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Sporting Glowing Skin: Athletes' Beauty Routines
Feeling inspired by the Olympic athletes? Don't forget that they need to match their skincare routine to their training routine. We'll share their easy to follow skincare tips to give your skin the same boost on the outside as working out gives it from the inside.
- Lip Balm – Keep lips moisturized throughout your work out to prevent chapping.
- Sunscreen – When exposed in the sun, athletes should be protecting their skin from the damaging rays of the sun by using lotions with an SPF of at least 30.
- Moisturizing – Keep your skin properly hydrated by moisturizing your skin whenever possible to keep the sweat and other elements from causing your skin to become tight and dry.
- Drinking Water – Staying hydrated is particularly important during exercise. Adequate fluid intake is essential to comfort, performance and safety. Take a look at our post on The Importance of Water for Your Skin and Health.
- Change Clothes - Be sure to change out of your sweaty clothes as soon as you finish your workout as they can be a magnet for germs and trapping dirt.
- Cleansing – Let your pores breathe by washing off sweat from your body shortly after your workout. This step will keep dirt, oil, toxins, and bacteria and other surface debris from collecting in your pores, causing breakouts.
Olympic beach volleyball champions Kerri Walsh Jennings and Misty May-Treanor chose the Clarisonic face brush to help keep them looking great during competition by cleansing their skin from sweat and sunscreen covering their bodies after practice and tournaments. Another Olympian, Natasha Hastings, an American sprint runner, also uses the Clarisonic system to make sure she looks her best at the track.
With the right skincare regimen, your skin can stay healthy and happy, allowing you to stay at the top of your game.
What is your post-workout beauty routine?
Photo by Allure Daily Beauty Reporter


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Chemotherapy, radiation therapy, and surgery are methods used to treat rectal cancer. Radiation therapy is associated with side effects such as diarrhea and other bowel problems, so doctors want to find a way to determine which patients with locally advanced rectal cancer need radiation and which can be spared radiation without compromising the effectiveness of their treatment.
This phase II/III study is seeking to determine how well chemotherapy alone compared to chemotherapy plus radiation therapy works for treating patients with rectal cancer undergoing surgery. Patients will be randomly assigned to one of two groups:
To be eligible for this study, patients must meet several criteria, including but not limited to the following:
For more information about this study and to inquire about eligibility, please contact Dr. Leonard Saltz at 646-888-4181.


text: July 5, 1964 Sun. morning Dear Dad, It's been so good to have your letters, and it was good to talk with you the other night. I hope you had a good trip to Holstein [1]; are the grandparents okay? Also hope you had a relaxing time yesterday with the Porterfields. I have been trying to get some "clues" about when the time would be best for you to come - most interesting for you, etc. The health team doesn't come 'till Aug. 1st, as far as I know, but I'm going to speak with Doc Henry (Aaron) about the whole deal today. I suggest that we'd be into our programs better next week than the coming one, if these are both the best weeks for you, but this week is fine too, because there's always a lot going on. On the other hand, perhaps you'd enjoy traveling down with Dean or the Shattucks when they come in Aug. As things are going now, I'd like to stay 'till at least the middle of or end of August. I must write to Mother and the boys. Shall try to do it today.


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As one of the world's fastest growing economies, China has been a favorite destination for foreign investment since it opened its doors to foreign investors almost three decades ago
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they really like to drum up hype and then have little to show for it
Phoronix: Ubuntu 13.04 Will Be Released, Rolling Fate Unknown
At the first day of Canonical's inaugural virtual Ubuntu Developers' Summit, it was decided to release Ubuntu 13.04 as scheduled. The fate of turning Ubuntu into a rolling release distribution for non-LTS releases is undecided...
they really like to drum up hype and then have little to show for it
A rolling release might get me back into Ubuntu as my main OS again.
I'm about to give out hope and get into Arch. Would have done it already if I wasn't too lazy.
they really like to drum up hype and then have little to show for it
In Linux, programming and IT in general there are always some myths that tend to spread because most think "they know" and know shit...
One such myth is that a rolling release model equals instability. This is totally BS for anyone who has used a rolling release distro in the past. It makes me lose my hope for humanity each time some moron perpetuates this myth...
"I am a
of the wasteland.
I am just
making it up
as I go along"
Why not have the universe repository be rolling?
While keeping the main repository the way it is?
Or keep software-installed-by-default (software shipped on the ISO image) the way it is, but user-installed-software be rolling?