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Yalac - Comparisons, How the evaluation release compares to other compressors |
Yalac - Comparisons, How the evaluation release compares to other compressors |
Apr 10 2006, 07:30
TAK Developer Group: Developer Posts: 1101 Joined: 1-April 06 Member No.: 29051 |
In this thread the testers should post comparisons of the preset modes of Yalac (Working name for "Yet another lossless audio compressor") with other lossless compressors. The results for specific variations of individual encoder options should go into the thread " Yalac Evaluation and optimization". Guidelines Please post the exact version number of the compressors. Compression ratio should be specified in percent of the uncompressed file size. Speed figures should be specified as multiple of real time (duration of the test files). A specification of your test system, especially the CPU, would be helpful. Open end: Feel free to add more results later. What happened Bad timing of my introduction (April 1.) forced an early publication of an evaluation release of Yalac, to prove, that it really works. This are results of 8 forum members, who where so kind to test the experimental release for me. Many thanks! Goals Yalac should finally achieve compression ratios on par with Monkey's Audio High. Decoding speed should be at least two times higher than Monkey and never be significantly lower than with FLAC (possibly Yalac will later be integrated into FLAC). My next steps The first results i have received from the testers show me some weaknesses of the encoder. That's a good thing, because that means, that there definitely is a chance to increase the compression efficiency! Same is true for the speed; especially the decoder is not fully optimized yet. But it will take some time, before i will come up with an optimized release. Links to 24 bit files i have used I think, they are hard to find. CODE 44 KHz, 24 bit mytek_8X96_24bit_web.wav Mytek-stereo96adc_evans.wav Mytek-stereo96adc_ravel.wav Source: http://www.mytekdigital.com/compare/comparison1.htm 48 KHz, 24 bit McDougalsMen24bit_48kHz.wav sister24bit_48kHz.wav Source: http://ff123.net/samples.html Or make a better Google search. foosion shows you how: http://www.hydrogenaudio.org/forums/index....ndpost&p=381702 This post has been edited by TBeck: Apr 12 2006, 20:23 |
May 15 2006, 11:09
Group: Super Moderator Posts: 4887 Joined: 12-August 04 From: Exeter, UK Member No.: 16217 |
I hacked the original comparison table to include only the original Yalac runs and the new 0.06 runs:
<link removed> Edit: now back: http://synthetic-soul.co.uk/comparison/yalac/ Edit: I just realised that the previous tests were on versions of Yalac earlier than 0.05. Therefore to do a comparison I really need to run some 0.05 tests. I'll reinstate the link when I have done so. This post has been edited by Synthetic Soul: May 15 2006, 15:46 -------------------- I'm on a horse.
May 15 2006, 12:52
TAK Developer Group: Developer Posts: 1101 Joined: 1-April 06 Member No.: 29051 |
Edit: I just realised that the previous tests were on versions of Yalac earlier than 0.05. Therefore to do a comparison I really need to run some 0.05 tests. I hope, it's not to late: For me the comparison of Preset FAST with V0.05 is the most important! Hence there is no urgent need to test the other presets of V0.05. |
Lo-Fi Version | Time is now: 6th May 2015 - 21:49 |


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Iowa Insurance Division
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Insurance Division Issues Cease and Desist Orders to Two Dubuque Investment Sellers
The Iowa Insurance Division has taken steps to protect consumers by issuing an order to prohibit sales activities by James J. Healey and Jerald Lee Woods both of Dubuque.
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Science Features
Increased dust storm activity may result from enhanced aridity in the Southwest, according to a USGS study.
Interior's Climate Science Centers helping coastal tribes and indigenous peoples prepare for climate change. Read more
Game of Thrones is one big earth science lesson!
Helping prepare communities for climate impacts. Read more
Reef corals are finding refuge from warming seawater temperatures, increased solar radiation and ocean acidification in an unlikely place. Read more
Once again, an extreme retreat of Alaska's summer sea ice has led large numbers of Pacific walruses to haul out on land instead of on offshore ice. Read more
Careful estimates of the future look of the land. Read more
Indigenous peoples are especially vulnerable to the effects of climate change – Interior's Climate Science Centers collaborate with them to develop adaptation strategies. Read more
Accurate elevation data heighten climate investigations worldwide. Read more
A new plan aims to improve coordination of Earth observation efforts among government agencies. Read more
USGS releases an assessment of biologic carbon sequestration for the eastern United States. Read more
Become an iCoast citizen scientist and help identify coastal changes using aerial photographs! Read more
Water is key to life on Earth. Read more
On March 3, the U.S. Geological Survey marks 135 years of science for America. Read more
The Olympics is the world's premier athletic competition but also a tribute to Earth science. Read more
The extent and distribution of the world's ice, primarily in the form of glaciers, provide insight about changes in the Earth's climate and changes in sea-level. Read more
For the first time, all of Iceland's glaciers are shown on a single map. Read more
Thoroughly tested and calibrated, Landsat 8 officially begins round-the-clock and round-the-world duty on May 30. Read more
Crews respond to spring flooding in the Midwest and Northern Plains. Read more...
The USGS is ready to address some of society's most critical issues for years to come. Read more
Join citizens and scientists in tracking The Pulse of Our Planet!
On March 3, the U.S. Geological Survey turned 134. Established by Congress in 1879 and built on a legacy of impartial science, the bureau faces unusual challenges in the near term.
The Nation's next Earth-observing satellite was successfully launched on February 11. Once it is mission-certified in orbit, the satellite will become Landsat 8. Read more
The recent past sheds light on preserving the future of economically and ecologically important native trout populations across the West. Read more
Watch USGS scientists in the Arctic track Pacific walruses to examine how these animals are faring in a world with less sea ice. Read more
The world's longest-running Earth-observing satellite program.
Dust storms July 21-22 blinded motorists, grounded flights and knocked out electricity. What's causing the dust storms?
The majority of the nation is facing dry conditions; in most areas drought conditions are expected to persist or intensify. Read more
A contest to celebrate 40 years of Landsat. Read more
Please comment on the USGS' draft science strategies! Read more
Timing is everything! Consider helping track changes in spring's arrival
Need a historical map for your genealogy research? You are in luck. We've got what you need! Download and view USGS historical maps from the comfort of your own home.
Flood Safety Awareness Week is March. 12-16. What can you do to prepare?
National Groundwater Awareness Week is Mar. 11-17, 2012. See how USGS science is connecting groundwater and surface water.
Since Japan's March 11, 2011, Tohoku earthquake and subsequent tsunami, scientists at the USGS have learned much to help better prepare for a large earthquake in the United States.
Five USGS employees honored with Distinguished Service Awards for their service to the nation
The USGS and UNESCO have produced a book that gives us a new way to look at our shared global heritage.
Groundwater in aquifers on the East Coast and in the Central U.S. has the highest risk of contamination from radium, a naturally occurring radioactive element and known carcinogen.
The proposed USGS budget reflects research priorities to respond to nationally relevant issues, including water quantity and quality, ecosystem restoration, hydraulic fracturing, natural disasters such as floods and earthquakes, and support for the National Ocean Policy, and has a large R&D component.
Caribou expert Layne Adams discusses the lives of reindeer — apart from their famous role on Christmas Eve. How they survive the cold.
Climate science is helping to predict food shortages, identify impacts on human health, and prepare for future conditions.
As demand grows, Landsat data can help us track trends in key resources. Remote-sensing satellites help scientists to observe our world, monitor changes, and detect critical trends in forestry, water, crops, and urban landscapes. Learn more.
A new study provides crucial information for difficult decisions regarding conservation, economic interests, and food and water security. Projected changes for 2010-2099
It's only the beginning of their careers, but these 3 young scientists have forged ahead with innovative research at the frontiers of science. How they've transformed their fields
Oct. 9-15, 2011, is Earth Science Week, themed "Our-Ever Changing Earth," and Oct. 12, 2011, is International Day for Natural Disaster Reduction. Answers to questions posed by a changing world
By 1936, devastating losses of wildlife populations were threatening the Nation's natural resource heritage. America's first wildlife research center
A dust storm on Tuesday, October 4, blinded motorists and caused a large string of motor vehicle crashes, multiple injuries, and at least one death. What's causing the dust storms?
USGS scientists study walruses off the northwestern Alaska coast in August as part of their ongoing study of how the Pacific walrus are responding to reduced sea ice conditions in late summer and fall.
USGS scientists are collecting water samples and other data to determine trends in ocean acidification from the least explored ocean in the world.
In support of the Famine Early Warning Systems Network, USGS scientists use satellite remote sensing to assess agricultural conditions that foretell famine.
New USGS research shows that rice could become adapted to climate change and some catastrophic events by colonizing its seeds or plants with the spores of tiny naturally occurring fungi. The DNA of the rice plant itself is not changed; instead, researchers are re-creating what normally happens in nature.
Now that field work has wrapped up at the Ice Age "Snowmastodon" fossil site near Snowmass Village, Colo., USGS and other scientists will begin work on unraveling the climate and environmental history of the area.
USGS scientists are studying the Earth's conditions 3 million years ago to gain insight into the impacts of future climate. Join us Aug. 3 in Reston, Va., to learn how this information is used to better understand the magnitude of changes forecast for the end of this century.
USGS crews continue to measure streamflow and collect water quality and sediment samples in the Ohio and Mississippi River basins using state-of-art instruments.
Over the past four decades, about 14% of the ice and permanent snow of Washington's Mount Rainier has melted due to combined recent warming and reduced precipitation.
USGS science supports management, conservation, and restoration of imperiled, at-risk, and endangered species.
In a unique application of data, this year's report provides the nation's first assessment of birds on public lands and waters.
The USGS, NASA, and other organizations and Federal agencies are studying how climate change affects wildlife and ecosystems.
Early maps of America, documents establishing the provenance of the Hope Diamond and documentation of explorations of the American West-- Join us in discovering the many treasures of the USGS Library.
Using coral growth records and measurements of changing ocean chemistry from increased atmospheric CO2, USGS scientists are providing a foundation for predicting future impacts of ocean acidification and sea-level rise to coral reefs.
Provide your input on the draft USGS Global Change Science Strategy by April 8, 2011.
Sea-ice habitats essential to polar bears would likely respond positively should more curbs be placed on global greenhouse gas emissions, according to a new modeling study published today in the journal, Nature.
Landscape photos taken in the same place but many years apart reveal dramatic changes due to human and natural factors. The USGS Desert Laboratory Repeat Photography Collection, the largest archive of its kind in the world, is 50 years old.
Decreasing pH and warming temperatures are changing ocean conditions and affecting coral and algal growth in South Florida. USGS scientists are conducting field measurements to learn more.
Many coastal wetlands worldwide including several on the U.S. Atlantic coast may be more sensitive than previously thought to climate change and sea-level rise in the this century.
USGS findings support recent predictions that climate change will stress ecosystems at lower elevations more than higher elevations. This information may guide future conservation efforts in helping decision makers develop regional landscape predictions about biological responses to climate changes.
The Earth as Art 3 collection, the latest set of Landsat satellite images selected for their artistic quality, reveals an intricate beauty in Earth's natural patterns.
USGS scientists are investigating sea turtles and their habitats in Dry Tortugas National Park to provide insight that will be used as decision-support tools for managing coral ecosystems.
Looking for information on natural resources, natural hazards, geospatial data, and more? The USGS Education site provides great resources, including lessons, data, maps, and more, to support teaching, learning, K-12 education, and university-level inquiry and research.
The timing of animal migration and reproduction, and observing when plants send out new leaves and bear fruit, is increasingly important in understanding how climate change affects biological and hydrologic systems. Photo credit Copyright C Brandon Cole.
The United States Group on Earth Observations (USGEO) is working to connect Earth observations with public health, agriculture, climate, and data management and dissemination.
USGS studies the relationships among earth surface processes, ecological systems, understanding current changes in the context of prehistoric and recent earth processes, distinguishing between natural and human-influenced changes, and recognizing ecological and physical responses to changes in climate.
Get ready to fall in love as the fall season approaches.
7 p.m.—Public lecture (also live-streamed over the Internet)
USGS-led survey finds that national wildlife refuges rate highly with visitors.
As the climate has warmed, many plants are starting to grow leaves and bloom flowers earlier. A new study published in the journal, Nature, suggests that most field experiments may underestimate the degree to which the timing of leafing and flowering changes with global warming.
Stressed agricultural lands may be releasing less of the moisture needed to protect the breadbasket of a continent.
Spring rains in the eastern Horn of Africa are projected to begin late this year and be substantially lower than normal.
In recognition of World Forestry Day, let's take a glimpse at USGS science to understand the fate of forests from climate change.
A new study concludes that fossil fuel emissions are likely contributors to a substantial amount of organic carbon found on glaciers in Alaska. Fossil fuel emissions, which contain organic carbon, can speed up the rate of glacier melt when deposited on glacier surfaces. In addition, the organic molecules associated with these deposits can be transportedContinue Reading
The U.S. Geological Survey had a very busy 2011 — below are a few of our highlights from last year.
Despite news articles warning of large-scale releases of methane due to climate change, recent research indicates that most of the world's gas hydrate deposits should remain stable for the next few thousand years.
Join us on February 1 to view the Earth from space, and discuss the profound impact Landsat has on many facets of our economy, safety, and environment.
Scientists have discovered an outbreak of coral disease called Montipora White Syndrome in Kāneohe Bay, Oahu. The affected coral are of the species Montipora capitata, also known as rice coral.
USGS scientists will join thousands of scientists, managers, and decision makers in Boston this week to present new findings on toxics at the Society for Environmental Toxicology and Chemistry (SETAC) conference in the Hynes Convention Center, Nov. 13-17.
On Nov. 3, USGS scientists Patrick Barnard and William Ellsworth will present a public lecture in Menlo Park, CA, providing Bay Area residents information about USGS research in the San Francisco Bay Area, including recent discoveries beneath San Francisco Bay and ongoing studies to better understand earthquake probabilities and the potential hazards associated with strong ground shaking.
Rivers and streams in the United States are releasing substantially more carbon dioxide into the atmosphere than previously thought.
Climate Change Impacts to Tribal Communities The USGS is working with Native American communities and organizations to understand climate change impacts to their land and neighborhoods. Projects include interviews with indigenous Alaskans to understand their personal observations of climate change, as well as studying how climate change is impacting sand dunes and posing risksContinue Reading
As climate changes, it affects the timing of when leaves emerge, the amount of foliage that grows as well as the timeframe when leaves begin to fall.
How will accelerated glacial melting over the next 50 years as a result of climate change affect the unique Gulf of Alaska and Copper River coastal ecosystems? USGS scientists are studying these processes and impacts.
USGS scientists are assessing the potential to remove CO2 from the atmosphere for storage in other Earth systems through a process called carbon sequestration.
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Page Last Modified: February 2, 2011


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Let's Talk Education
By Rebecca Teti
Fridays: Education
(Join each day's Coffee Talk discussion: Mon: Parenting; Tues: Open Forum; Wed: NFP; Thu: Marriage; Fri: Education; Sat/Sun: Changing Roles)
Whether your children attend school or are homeschooled, this is the spot to ask questions about curricula, religious education, parent-teacher relationships, or academic concerns of any kind.
Please join us!
Anyone recommend materials for talking to your children about sexuality? It looks like we'll be having this conversation with our 10-year old sooner rather than later (thank you, Boy Scouts of America). We've been educating him generally his whole life, and we have a good handle on the Theology of the Body. Just wondering if anyone used any specific materials that they found helpful.
Dr. Colleen Kelly Mast has an entire curriculum called Love and Life. There is a student book and parent book. Also, I am looking at Jason Evert's Theology of the Body for Him/Her (it has two "fronts" with a flip over format) currently and it is very good. As a parent, I have found it best to educate myself so I will be ready when the opportunity arises rather than have formal discussions. God bless your discussions!
We enjoyed using Passport2Purity® - Family Life Today www.familylife.com/find-help/key-resources/passport2purity The Passport2Purity Getaway Kit helps build heart-to-heart communication between you and your pre-teen while laying a foundation of purity that will prepare ...
Here's a simple approach: http://www.patheos.com/blogs/duffy/2013/05/towards-a-true-sex-education/
"Listen Son" http://www.ewtn.com/library/FAMILY/LISTENSN.TXT Also, it can be purchased through AngelusPress http://angeluspress.org/Books/Family-Life/SET-Listen-Son-/-Mothers-Little-Helper
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Welcome to Our Bed and Breakfast in Beautiful Jackson, New Hampshire
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Results 1 to 5 of 26
May 29th, 2013 07:12 AM #1Member
- Join Date
- May 2013
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Help with baby girls name - arriving in June!
Hi all,
This is my first post, though I'm a long time reader and searcher!
We're having a huge amount of trouble narrowing down our names, and to be honest I'm not completely sold on the ones we are considering.
Firstly, we already have a Marilla Susan (NN Rilla, from Anne of Green Gables and Susan is a family name). Our first has LOADS of meaning to us and we had a boys name ready but we are blessed with another girl, so I'm feeling a bit out of my depth.
Marilla's a Leo (ruled by the sun) and this little one will be a Cancer (ruled by the moon).
Secondly, our last name is a food type (Oi!) and ends with "ey". So lots of my favourites have gone. (Sage, Violet, Rose etc).
These are some of the first names we have been consdering but am happy to hear other suggestions.
Adelaide nn Adie
Harriet nn Hattie
Willa (lots of Williams in the family line)
Magnolia - nn Nola or Maggie
Pheobe - nn Phe
Also middle names are a bit of a dead end though we have considered http://nameberry.com/babyname/Lillian to honour my Nana, it's her middle name, her first is Mabel, Charlotte to honour my mum (her middle name) but I like Lottie better or something "purple" as her Sister has always refered to her as the "purple baby". So Violet, Iris and Viola have been options.
Thanks in advance for any help!
May 29th, 2013 07:21 AM #3♥ Margaret Mary ♥
20. Name nerd. College sophomore. Identical twin.
★ Elza Josephine ★ Harriet Gloria ★ Ida Rosemary ★ Mary Jessamine ★ Rose Christabel ★ Sarah Margaret ★
★ Asher Benedict ★ Gabriel August ★ James Fletcher ★ John Constantine ★ Noah Alexander ★ Samuel Ernest ★
May 29th, 2013 07:58 AM #5
Adelaide, Harriet and Phoebe are nice enough but don't have quite the same feel as Marilla.
Willa sounds so much like Marilla that I'd leave it as a middle choice.
Magnolia, Luna and Sylvia are probably my picks of your list, although I think Sylvie might work slightly better with Marilla.
Some other suggestions you might like:
May 29th, 2013 06:32 PM #7Member
- Join Date
- May 2013
- Posts
- 95
BlueJuniper you've hit the nail on the head when you write
"Adelaide, Harriet and Phoebe are nice enough but don't have quite the same feel as Marilla.
Willa sounds so much like Marilla that I'd leave it as a middle choice".
I love Adelaide but don't feel it's a good match and I don't like Addy (ad-dee) as a nn but rather Adie (Aa-dee), but know what she'll probably get.
I do like Sylvia/Sylvie.
I also like Enid and Enid and a few other suggestions you said. Thanks!
May 29th, 2013 06:40 PM #9Senior Member
- Join Date
- Jun 2012
- Location
- Colorado
- Posts
- 445


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On December 13th I will be sober for 1 1/2 years. For the three years before that I drank once every 4-5 months and got drunk a couple of times (5-6 drinks in a short period). While I wasn't drinking heavily during that time, every time I drank one or two I had a burning desire to drink more. Most times I would not. This year I hae been married 4 years.
All that to say my wife does not know what I was like when I was drinking regularly and has never seen me when I really tie one on. She does on the other hand that an extreme example of self will run riot before I started working the Steps. My behavior and our marraige has been night and day different.
Up until this point, meetings have not been a part of my program for recovery. I actively work the steps, fellowship with friends who are recovering alcoholics, and regularly talk to my sponsor. I attended a few meetings but I never felt a strong pull to them. Until this past week. I woke up one morning and the statement "I need to start attending a meeting a week". So I have set up my schedule so I can get to an evening meeting each week and still be home 30-45 minutes after my wife gets home from work. We are both pretty busy and she is pregnant (we lost a child at 37 1/2 weeks this June) so I am trying to be respectful and considerate of her needs.
When I shared this with my wife she got frustrated with me. I run a group for kids weekly and meet with a group of men from church every other week. She asked me wasn't that enough and I told her it was not. She asked me why I don't put my family first and I told her that putting my sobriety before my family is the reason I have one to begin with.
Later on the evening she gave a general apology for not being "very nice" but didn't specifically say anything about me going to meetings. At the end of the day this is not on my side of the street and if I don't get myself to some meetings I am fairly certain there is going to be alot of stuff piling up on my side of the street.
At the end of the day my wife doesn't get it and that is frustrating. My sobriety might be a bit easier if my wife understood what really went on in my head but the book never said it was going to be easy. When I first started my journey my sponsor told me "boy (that's what he calls me most days) recovery is simply but it ain't easy".


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- Esophagogastric (1)
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- New histone deacetylase inhibitors as potential therapeutic tools for advanced prostate carcinoma (2008)
- The anti-epileptic drug valproic acid is also under trial as an anti-cancer agent due to its histone deacetylase (HDAC) inhibitory properties. However, the effects of valproic acid (VPA) are limited and concentrations required for exerting anti-neoplastic effects in vitro may not be reached in tumour patients. In this study, we tested in vitro and in vivo effects of two VPA-derivatives (ACS2, ACS33) on pre-clinical prostate cancer models. PC3 and DU-145 prostate tumour cell lines were treated with various concentrations of ACS2 or ACS33 to perform in vitro cell proliferation 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assays and to evaluate tumour cell adhesion to endothelial cell monolayers. Analysis of acetylated histones H3 and H4 protein expression was performed by western blotting. In vivo tumour growth was conducted in subcutaneous xenograft mouse models. Tumour sections were assessed by immunohistochemistry for histone H3 acetylation and proliferation. ACS2 and ACS33 significantly up-regulated histone H3 and H4 acetylation in prostate cancer cell lines. In micromolar concentrations both compounds exerted growth arrest in PC3 and DU-145 cells and prevented tumour cell attachment to endothelium. In vivo, ACS33 inhibited the growth of PC3 in subcutaneous xenografts. Immunohistochemistry and western blotting confirmed increased histone H3 acetylation and reduced proliferation. ACS2 and ACS33 represent novel VPA derivatives with superior anti-tumoural activities, compared to the mother compound. This investigation lends support to the clinical testing of ACS2 or ACS33 for the treatment of prostate cancer.
- Phase I clinical study of the recombinant antibody toxin scFv(FRP5)-ETA specific for the ErbB2/HER2 receptor in patients with advanced solid malignomas (2005)
- Introduction: ScFv(FRP5)-ETA is a recombinant antibody toxin with binding specificity for ErbB2 (HER2). It consists of an N-terminal single-chain antibody fragment (scFv), genetically linked to truncated Pseudomonas exotoxin A (ETA). Potent antitumoral activity of scFv(FRP5)-ETA against ErbB2-overexpressing tumor cells was previously demonstrated in vitro and in animal models. Here we report the first systemic application of scFv(FRP5)-ETA in human cancer patients. Methods: We have performed a phase I dose-finding study, with the objective to assess the maximum tolerated dose and the dose-limiting toxicity of intravenously injected scFv(FRP5)-ETA. Eighteen patients suffering from ErbB2-expressing metastatic breast cancers, prostate cancers, head and neck cancer, non small cell lung cancer, or transitional cell carcinoma were treated. Dose levels of 2, 4, 10, 12.5, and 20 μg/kg scFv(FRP5)-ETA were administered as five daily infusions each for two consecutive weeks. Results: No hematologic, renal, and/or cardiovascular toxicities were noted in any of the patients treated. However, transient elevation of liver enzymes was observed, and considered dose limiting, in one of six patients at the maximum tolerated dose of 12.5 μg/kg, and in two of three patients at 20 μg/kg. Fifteen minutes after injection, peak concentrations of more than 100 ng/ml scFv(FRP5)-ETA were obtained at a dose of 10 μg/kg, indicating that predicted therapeutic levels of the recombinant protein can be applied without inducing toxic side effects. Induction of antibodies against scFv(FRP5)-ETA was observed 8 days after initiation of therapy in 13 patients investigated, but only in five of these patients could neutralizing activity be detected. Two patients showed stable disease and in three patients clinical signs of activity in terms of signs and symptoms were observed (all treated at doses ≥ 10 μg/kg). Disease progression occurred in 11 of the patients. Conclusion: Our results demonstrate that systemic therapy with scFv(FRP5)-ETA can be safely administered up to a maximum tolerated dose of 12.5 μg/kg in patients with ErbB2-expressing tumors, justifying further clinical development.
- Phase I study of everolimus and mitomycin C for patients with metastatic esophagogastric adenocarcinoma (2013)
- This study aimed at determining the recommended dose of the mammalian target of rapamycin inhibitor everolimus in combination with mitomycin C (MMC) in patients with previously treated metastatic esophagogastric cancer. In this phase I trial, patients received escalated doses of oral everolimus (5, 7.5, and 10 mg/day) in combination with intravenous MMC 5 mg/m2 every 3 weeks. Endpoints were the dose-limiting toxicity (DLT), safety, and response rates. Tumor tissues were tested for HER2-status and mutations in the PTEN, PIK3CA, AKT1, CTNNB1, and E-cadherin type 1 genes. Sixteen patients (12 male, four female) with gastric/gastroesophageal junction cancer were included. All patients were previously treated with a platinum-based chemotherapy. Treatment cohorts were: 5 mg/day, three patients; 7.5 mg/day, three patients; and 10 mg/day, 10 patients. No DLTs occurred during dose escalation. Most frequent grade 3 toxicities were leukopenia (18.8%) and neutropenia (18.8%). All other grade 3 toxicities were below 10%. No grade 4 toxicities occurred. Three (18.8%) patients experienced partial responses and four patients had stable disease (SD). Antitumor activity according to Response Evaluation Criteria In Solid Tumors (RECIST)-criteria was highest in the 10 mg/day cohort. No associations between HER2-status or detected mutations and response were observed. The recommended dose of everolimus combined with MMC is 10 mg/day. Encouraging signs of antitumor activity were seen (http://www.ClinicalTrials.gov; Clinical trial registration number: NCT01042782).
- untitled document (2006)
- Following publication of the data presented by von Minckwitz and colleagues [1] it has been brought to our attention that some patients should be scored differently. Stable disease was seen in three of the eighteen patients instead of two of the eighteen patients: one patient with transitional cell carcinoma treated at 4 micro g/kg scFv(FRP5)-ETA per day, and two breast cancer patients treated at 4 and 12.5 micro g/kg scFv(FRP5)-ETA per day. Disease progression occured in 9 of the eighteen patients evaluated (see corrected Table 2 overleaf). This does not affect the conclusions of our study. In addition we would like to correct the following errors: patient IDs for patients U01 and U02 in the original Table 2 were interchanged. In addition, patient N03 had a grade 3 elevation of gamma-glutamyl transferase, and not grade 2 (see corrected Table 2 overleaf). http://publikationen.ub.uni-frankfurt.de/volltexte/2005/1156/


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Bluebonnet's Liquid Calcium Magnesium Citrate Plus Vitamin D3 provides 1200 mg of calcium and 600 mg of magnesium in a 2:1 ratio, plus 800 IU of vitamin D3 from lanolin in one delicious, naturally flavored liquid formula.
Directions for Use: As a dietary supplement, take two tablespoons (30 ml) daily or as directed by a healthcare practitioner. Can also be a good source of calcium and magnesium in baked goods.
* Daily value not establishedThese statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.
Other IngredientsPurified water, Fructose, citric acid, natural strawberry flavor, xanthan gum, sea vegetable extract.Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soybeans.Also free of yeast, gluten, barley, rice and sodium.


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Topic OverviewIs this topic for you?This topic covers depression in adults. For information on:
What is depression?Depression is an illness that causes you to feel sad, lose interest in activities that you've always enjoyed, withdraw from others, and have little energy. It's different from normal feelings of sadness, grief, or low energy. Depression can also cause people to feel hopeless about the future and even think about suicide. Many people, and sometimes their families, feel embarrassed or ashamed about having depression. Don't let these feelings stand in the way of getting treatment. Remember that depression is a common illness. It affects the young and old, men and women, all ethnic groups, and all professions. If you think you may be depressed, tell your doctor. Treatment can help you enjoy life again. The sooner you get treatment, the sooner you will feel better. What causes depression?Depression is a disease. It's not caused by personal weakness and is not a character flaw. When you have depression, chemicals in your brain called neurotransmitters are out of balance. Most experts believe that a combination of family history (your genes) and stressful life events may cause depression. Life events can include a death in the family or having a long-term health problem. Just because you have a family member with depression or have stressful life events doesn't mean you'll get depression. You also may get depressed even if there is no reason you can think of. What are the symptoms?The symptoms of depression may be hard to notice at first. They vary among people, and you may confuse them with just feeling "off" or with another health problem. The two most common symptoms of depression are:
A serious symptom of depression is thinking about death or suicide. If you or someone you care about talks about this or about feeling hopeless, get help right away. If you think you may have depression, take a short quiz to check your symptoms: How is it treated?Depression can be treated in various ways. Counseling, psychotherapy, and antidepressant medicines can all be used. Lifestyle changes, such as getting more exercise, also may help. Work with your health care team to find the best treatment for you. It may take a few tries, and it can take several weeks for the medicine and therapy to start working. Try to be patient and keep following your treatment plan. Depression can return (relapse). How likely you are to get depression again increases each time you have a bout of depression. Taking your medicines and continuing some types of therapy after you feel better can help keep that from happening. Some people need to take medicine for the rest of their lives. This doesn't stop them from living full and happy lives. What can you do if a loved one has depression?If someone you care for is depressed, the best thing you can do is help the person get or stay in treatment. Learn about the disease. Talk to the person, and gently encourage him or her to do things and see people. Don't get upset with the person. The behavior you see is the disease, not the person. Frequently Asked Questions
eMedicineHealth Medical Reference from Healthwise This information does not replace the advice of a doctor. Healthwise disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions. To learn more visit Healthwise.org © 1995-2014 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated. |


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$270 $140
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Evaluating Deduplication Solutions: What you really should consider
Click here to download now
Overview: Do you know what deduplication is, and how it can benefit your company? Deduplication is one of the hottest technologies on the market today because it reduces your data storage costs across the board while increasing IT productivity.
Learn more about deduplication - and how it makes your life easier! - in this new white paper. See what you must consider when looking at deduplication, and how the implementation approach you choose will affect your environment


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Home > Health & Wellness > Health Library > Back Surgeries for Tumors and Infections
You might have surgery if your back problem is caused by a tumor or infection.
Spinal tumors can be cancerous (malignant) or not (benign). During surgery, the doctor removes the tumor and any bone that it has damaged.
If surgery or disease has weakened part of the spine, the doctor can make it more stable using metal implants, bone grafts, or bone cement.
Certain types of tumors grow on the spinal cord or nerve roots. In some cases, surgery to remove the tumor could cause more harm to the spinal cord than not removing the tumor. Talk to your doctor to make sure you understand the risks involved. Get advice from a surgeon who is an expert in treating spinal cord tumors.
This surgery removes bone and other infected or abnormal tissue. It's usually done to treat an infection or an injury.
The doctor removes infected and damaged or dead bone. The area is then cleaned with a sterile solution that contains antibiotics. If the doctor removes a lot of bone or entire vertebrae, he or she may use spinal fusion (arthrodesis) to make the spine stable.
ByHealthwise StaffPrimary Medical ReviewerWilliam H. Blahd, Jr., MD, FACEP - Emergency MedicineSpecialist Medical ReviewerRobert B. Keller, MD - Orthopedics
Current as ofJune 4, 2014
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Medical Review: William H. Blahd, Jr., MD, FACEP - Emergency Medicine & Robert B. Keller, MD - Orthopedics
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D-backs, Brewers entering break at opposite ends
Arizona aims for season sweep in final meeting with Milwaukee
No matter what happens Sunday against the Brewers, the D-backs will enter the All-Star break atop the National League West.
"Nobody really picked us and the fact that we're in first place with all the obstacles we've overcome, it's exciting," said third baseman Eric Chavez. "I think we've somewhat overachieved. We've done better than maybe people expected."
The D-backs are sitting six games above .500 entering Sunday, despite an MLB-leading 19 blown saves this season.
"Hopefully it's something that won't come back to bite us," Chavez said. "Those games are tough. If you go into the last week of the season and you're only up one or two games, it wouldn't be much of a race if we had won those."
Arizona will send Ian Kennedy to the mound Sunday, and the D-backs' Opening Day starter will be looking to put his first-half struggles behind him. Kennedy stumbled in his last start, picking up his fifth loss as he gave up five earned runs on nine hits and three walks in 5 2/3 innings.
The Brewers will counter with right-hander Wily Peralta, who is coming off a three-hit shutout of the Reds on Tuesday with his mother observing from the stands for the first time in his professional career.
The 2-0 victory was also Peralta's first complete game.
"I've been thinking about it all my career, like, 'When am I going to throw a complete game?'" Peralta said after the start. "The shutout was a blessing for me."
In contrast to the D-backs' first-place status, the Brewers will enter the break in the cellar of the NL Central as one of only five Major League teams yet to reach the 40-win mark.
D-backs: Parra's status unknown for Sunday
Outfielder Gerardo Parra sat out a for second consecutive day and the fourth time this month on Saturday night.
Parra had two days off earlier this month after crashing into the outfield wall while trying to make a running catch against the Mets on July 1. Parra is batting just .154 this month after hitting .305 in April and .311 in May.
"It'll be good for him, because of the way he plays," manager Kirk Gibson said of the time off. "The one against the Mets, it's like he got in a car accident. He sacrificed himself. He's just beat up so I made that decision. If you look at the numbers, you might figure it out."
Brewers: Segura still going strong
All-Star shortstop Jean Segura played in his 91st game Saturday, having missed just two the entire season.
Segura had played only 45 big league games prior to 2013, but the 23-year-old said he isn't feeling fatigued.
Segura's last day off was July 2, and he won't get much time off this week, as he will travel to New York for Tuesday's All-Star Game.
"I won't be able to take much of a break, but it's a fun game and it's going to be a good experience," Segura said.
Worth noting
• The D-backs enter Sunday's series finale with a chance for a sweep of the season series in their final meeting with the Brewers this year.
• Brewers starter Marco Estrada (on the disabled list since June 5 with hamstring and back issues) was scheduled to throw a bullpen session off flat ground Saturday, but it was pushed to Sunday.
Chad Thornburg is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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Knotted Back Maxi Dress
Out of Stock
Super soft jersey drapes beautifully from a smooth scooped neckline that changes to supportive Y-back straps with a twist. An easy-to-wear silhouette, it glides over curves to show off a vibrant on-trend graphic print. We love the way it looks with the Soft Jersey Open Wrap.
- Double-layered bodice.
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- 95% Rayon, 5% Spandex. Machine wash, cold. Imported.
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DARN TOUGH Ski Ultra Lite Socks
Item: 11902121 Product Description >
Price: $24.00
Socks - Buy 3 eligible packs or pairs and get 1 FREE! This item is eligible. Get Details
DARN TOUGH Ski Ultra Lite Socks
Made in Vermont, the Darn Tough Ultra Lite Ski socks use very fine Italian knitting machines to produce an extremely dense and durable knit.Features/Benefits:
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Top Definition
The replacement holiday for Christmas built on the belief that Santa is actually a Ninja due to his ability to get in and out of houses undetected. This holiday is typically followed 7 days later by New Chuck's Eve.
Merry Ninjamas
από EvilSpyBoy
9 Μάιος 2010
1 more definition
Only the best holiday ever. On December 3rd you have the chance to dress and act like the beloved ninja.
Dude1- I can't wait for ninja-mas!
Dude2- I alredy have my ninja stars polished!
Dude2- I alredy have my ninja stars polished!
από Samankerrkid
24 Νοέμβριος 2009


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So, how noisy is the fan and does it stay quiet under OpenSource linux drivers, or does it ramp up to keep the sucker cool? Noise is important to me since I wnat to build a new system which has decent OpenGL performance, but is also quiet.
Hmm... it would be nice to include a graph of price/FPS in your reviews, if only to show relative costs for a particular frame rate.
Also, Watts/FPS would be interesting to see to, if only to help gauge efficiency of the cards.


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Selected FAQ |
What driver should I use to print from my DOS applications? |
Epson did not write drivers for DOS applications except for a few very popular DOS programs like earlier verions of WordPerfect, Lotus and AutoCAD for DOS. The software companies usually provided the printer drivers with their software since each driver was unique to the application under DOS. In recent years most software has been developed for Windows so most of the newer Epson printers will not be listed among the printers supported in older DOS software. In your user's manual there is a list of printers to select if your exact model is not listed in your software. 24-Pin Printers If you have an EPSON Ink Jet printer, LQ or ActionPrinter Series 24-pin EPSON printer, you can try selecting one of the following printer models if they are provided with your software: LQ-2550 (color) LQ-860 (color) LQ-850 LQ-510 LQ-500 EPSON 24-Pin Compatible EPSON Compatible 24-Pin Dot Matrix Dot Matrix 9-Pin Printers If you have an EX, FX, LX, MX or ActionPrinter Series 9-pin EPSON printer, you can try selecting one of the following printer models if they are provided with your software: EX-Series (color) FX-Series LX-Series MX-Series EPSON 9-Pin Compatible EPSON Compatible 9-Pin Dot Matrix Dot Matrix |


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Five ways you can have fun this weekend:1. Sunday is the anniversary of the Pearl Harbor attack. The Japanese strike took place on Dec. 7, 1941, and 2,402 Americans were killed. Libraries, museums, historical societies and veterans groups might be commemorating the event, so check the paper for listings.2. The big movies opening at theaters this week are �Wild,� an R biopic starring Reese Witherspoon; and �The Pyramid,� an R horror flick.
By Tracy BeckermanMore Content Now
By Richard MontgomeryMore Content Now
Dear Dave,My wife and I are still paying off debt, so we didn�t budget anything for Christmas. How much do you think we should spend on close friends and family members?DanDear Dan,
All for a good cause
[WARNING: The following story contains spoilers from�Tuesday's�penultimate episode of�Sons of Anarchy.�Read at your own risk.]The penultimate episode of�
Each week, executive editor Adam Bryant satisfies your need for TV scoop. Please send all questions to�email@example.com'm still in shock...
Rosario Dawson�is a mom! The actress adopted a 12-year-old girl in October,�
Bobby Keys, who played saxophone for the�Rolling Stones�for more than four decades, passed...
Stephen Colbert, in Colbert fashion, explains why the lightsaber seen in the 88-second trailer for the new Star Wars Episode VII: The Force Awakens is so 'awesome'.
Dave Granlund cartoon about Mubarak's acquittal.
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proven track record of attracting and securing NEW
BUSINESS? Harvey County Economic Development
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Marketing Information
The Nfinity NB16C0712600 power system is a scalable 16kVA to 20kVA UPS, designed with N+x parallel redundancy to provide a fault-tolerant network of power protection. Its modular design was devised to provide easy scalability to users as their power demands grow. Configurations can be cost-effectively upgraded without re-investing in a new system or installation.The system's fault-tolerant design enables the intelligent power and battery modules to take themselves off-line if there is a problem without compromising system integrity. Self-diagnostic capabilities simplify maintenance and troubleshooting. It also offers redundancy in its unique paired system controls, internal and external bypass, and monitoring options.
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Welcome to the VISION BUICK GMC page, your Pirelli Tire dealer in your town or district. We are able to offer advice on all your tire needs. VISION BUICK GMC is located at 800 PANORAMA TRAIL.
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Bacteriophages shuttle genes between diverse ecosystems.
Many of the body's tissues can tell time, and these peripheral clocks can be influenced by environmental cues, such as the timing of food consumption.
The method to the dengue virus's maddening infectiousness.
Although fully organized patient-run trials are still few and far between, patients are taking a more active role in clinical research.
Some of these insidious viruses expertly subvert the host immune system, allowing their unhindered proliferation.
Fat cells behave differently in obese individuals, causing inflammation and insulin resitance.
Adipose tissue plays an immune role in individuals of normal wieght.
Present in every tissue of the body, ubiquitin appears to be involved in a dizzying array of functions, from cell cycle and division to organelle and ribosome biogenesis, as well as the response to viral infection. The protein plays at least two role
Despite its discovery as a protein that seems to show up everywhere, at least in eukaryotic cells, researchers are only beginning to scratch the surface of all of the cellular functions involving ubiquitin.
Gene therapies typically involve the introduction of genetic material into target cells to replace or supplement an existing, usually dysfunctional, gene.


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Omnia 42 MS PR Max Steel Privacy Door Leverset from the Max Steel Collection Featuring a 28 Degree Latch Rotation
Save on all Omnia Products!
Use Coupon Code: OMNIA at checkout to receive additional savings
Offer Ends 5/14/2015
Technical Specs
Specification Sheet | |
ADA | Yes |
Approved for Commercial Use | Yes |
Backset | 2-3/4", 2-3/8" |
Collection | Latchset Levers, Max Steel |
Function | Privacy |
Handing | Left, Reversible, Right |
Handle Material | Metal |
Handle Style | Lever |
Material | Stainless Steel |
Panic Proof | No |
Product Class | Residential |
Projection | 2.75 |
Rosette Shape | Round |
Shape | Flat, Straight |
Style | Contemporary/Modern |
Theme | Transitional |
Width | 4.125 |
Configure your Omnia 42 MS PR Privacy Door Leverset from the Max Steel Collection Featuring a 28 Degree Latch Rotation
Backset more info ▼
The backset of your door is the measurement from the edge of the door to the center of the bore hole. Some products have an adjustable backset latch; however this product does require a designation. -
Strike more info ▼
Strike plates are the protective metal plates installed in the door jamb that receives the latch. There are strike plate options available with this product. Please select from one of the options below. -
Please finish configuring product before adding to cart
Omnia 42PR Privacy Door Lever Set from the Max Steel Collection Featuring a 28 Degree Latch Rotation
Omnia's line of Max Steel Levers is designed to enhance any setting where a modern, sophisticated look is desired. Every piece is strong and durable, made from premium grade material and coupled with interior components that prove worthy of Omnia's exceptional standards.
- Interior lever features a privacy push button on the rose The exterior rose features an emergency release hole
- Turning the interior lever will release the privacy lock and retract the latch
- A Privacy Door Lever Set is commonly used for bedroom and bathroom doors
- The 2-7/16" Diameter Modern Rose (plate against the door) features concealed screws for a clean look.
- Will fit 2-1/8" bore
- For commercial and residential use
- 2-3/8" and 2-3/4" backsets available
- ADA compliant
- Concealed Screw Roses with Self Alignment and Spring Assistance
- Lever Length: 4-1/8"
- Lever Projection: 2-3/4"
Additional Omnia Links
- View Manufacturer Warranty
- Shop All Omnia Products
- Shop All Omnia 42 Lever Collection Products
Our SKU: 42PR
This product is listed under the following manufacturer number(s):
- Max Brass
42 MB PR - Max Steel
42 MS PR - Oil Rubbed Bronze
42 US10B PR - Polished Brass
42 US3 PR - Polished Chrome
42 US26 PR - Polished Nickel
42 US14 PR - Satin Chrome
42 US26D PR - Satin Nickel
*Denotes a finish or option that has been discontinued
Omnia 42 Lever Collection
Other Products In The Omnia 42 Lever Collection
Omnia 42SD
Single Dummy Door Lever from the Max Steel Collect...$56.25-$91.50
Omnia 42PA
Passage Door Leverset With 2-9/16" Round Modern Ro...$123.75-$194.25
Omnia 42PD
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Phoronix: Xfce-Based Xubuntu Will Not Ship XMir For 13.10
The Xubuntu team, the derivative of Ubuntu Linux focused around shipping the Xfce desktop environment, has decided against using XMir for their 13.10 release after extensive testing...
Xubuntu is a fantastic alternative to Ubuntu for those prefer a more classical/simple environment and/or a superlight experience. XMir or XWayland wouldn't be a logical move as long as there is performance impact. Xorg (probably for last time) is a good choice for 13.10
PS i don't think XMir and XWayland will have so big performance impact in the future. They are under heavy development and optimization is totally missing. We must not forget that they are created as a transition solution to Mir and Wayland.
Last edited by verde; 08-22-2013 at 06:47 PM.
"More good news from this Xubuntu meeting is that t..."
good post. i don t come to phoronix again this a stupid way to bring news
I'm glad to read this. This means I've got more time with Xubuntu.
No, that's only Xmir. Which is why it's totally idiotic.
XWayland is meant to offer backwards compatibility to legacy X apps (including GTK2, Qt3/4, Motif, etc). It is not meant to run whole X DE's on top of it. Because that would be unbelievably stupid. Almost as stupid as what Canonical is doing with Xmir right now.


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1976-07-15 Char-Koosta News |
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Mission Valley Miracle Dijfcbn: The Tribal Council has decided to allocate $100, 000 of Federal Revenue Sharing money to the Mission Val -ley Miracle, a fund raising project for a nursing home addition to St. Luke's Hospital in Ronan. This facility claims to treat more Indian Volume 6 Number 6 patients than any o-ther one in the Valley. The private, nonprofit group had recently shown the Council that those in need of regular, medical, care and attention in a nursing home had to leave their families and go elsewhere. It was emphasized that it would differ from a non-medical resthome, and that patients would be seen by a doctor eachday. The motion , made by Pat Lefthand and seconded by Louie Adams, passed, 6 to 2. Bill Morigeau & Tom Pablo opposed. FULL MOON OF THE SER VICEBER R Y ACCIDENT REPORT Accidents on the Flathead Reservation for the Month of June 1976- 1_3_ Accidents 34_ People involved 1_7_ injured 0_2_ Deaths 06_ Alcohol Related 0_1_ Non-Alcohol 0_7_ Indian 2_7_ Non- Indian July 15, 1976 Vicki Morigeau Crowned Miss Flathead Vickl Morigeau, IS oi Dixon, daughter. 0? Sonny and Bev Morigeau, was crowned MibS Vlathead Reservation at the 4th o i July celebration in Arlee. Vicki was the only contestant to enter, the contest I0K women age 18 to 25. The Junior. Miss Flathead is Juanita Sanckez, o i Arlee, daughter o i Baldemario and Clarice Sanchez. Ut runner, up was bileen Morigeau, Dixon, and 2nd Êèïïîë up was Mary Ann Benalty 0{ St. Ignatius. Vicki lb shorn here being congratulated by Committee Chairman Doug Allar.d. August Per Capita Dixon: The Tribal Council has passed a $500 per-capita payment to be sent out the middle part of August. Enrollment Clerk, Jan McClure, says there were 5,853 Tribal members on the rolls as of June 30, ]976. This figures out to be a dividend payment of $2,926,500. The $500 August payment is in addition to the $100 per-capita paid out last December, giving a total payment of $600 for the year to each member. If you have recently moved and have an address change to make with the Tribal office, you may contact Jan at Flathead Sub-agency, Dixon, Mont., 59831, or phone 21+6-3595, as soon as possible.
Object Description
Rating | |
Title | 1976-07-15 Char-Koosta News |
Creator | Confederated Salish and Kootenai Tribes of the Flathead Reservation. |
Subject | Salish Indians --Newspapers.; Kutenai Indians --Newspapers.; Pablo (Montana) --Newspapers.; Kootenai Indians |
Description | Mission Valley Miracle; Vicki Morigeau crowned Miss Flathead; August Per Capita; Accident report; Fishing violators found guilty; Jim Grinder is 108; Arlee celebration was a succes; Dance contest winners; Arlee Rodeo results; Arlee Parade contestants; Washington D.C. Trip: Report from Johnny Arlee. |
Publisher | Confederated Salish and Kootenai Tribes of the Flathead Indian Nation |
Date Original | 1976-07-15 |
Date Digital | 2007-05-02 |
Type | text |
Format | image/tiff |
Resource Identifier | Y54000155 |
Rights Management | Copyright (c) Salish and Kootenai Federated Tribes, all rights reserved. |
Contributing Institution | Salish Kootenai College |
Contributor | D'Arcy McNickle Library |
Source | CSKT PN 4883.J6 C4 |
Language | en |
Relation | Volume 6; Number 6 |
Digitization Specifications | Digitized at the University of Montana Maureen and Mike Mansfield Library; Scanned as master TIFF using Bookeye 3 scanner at 400 ppi, 8 bit grayscale; Optical Character Recognition with Abbyy FineReader Corporate Edition; Derivatives created using Photoshop CS |
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Recent Activity
In 2012, significant challenges to existing EU policy, from Schengen to the Common European Asylum System, have constituted the chief concerns for migration management for both EU Member States and the European Commission. Beyond EU borders, there will be additional pressure for the European Union to offer a more concerted humanitarian response to the Syrian refugee crisis affecting Europe's neighbor Turkey in 2013.
The electoral fortunes of far-right parties, a number of which campaigned using anti-immigrant messages, varied during 2012, with notable albeit small advances for Greece's extremist Golden Dawn party. For the most part, however, extreme-right politicians continue to struggle to build sizeable support; and in Europe, the anti-immigration discourse has been overshadowed by anti-Brussels rhetoric and anger over high unemployment and austerity measures.
Migration flows that were stalled for a period by the pronounced recession that began in 2008 have resumed to a number of OECD countries, including the United States where there appears to be a slight increase in Mexican migration for the first time in several years. More migrants seem to be choosing emerging economies, including Brazil, China, and South Africa, over traditional destinations.
Belgium is often overlooked as a country of immigration because of its size and its less known history of immigration. Yet over the last three decades Belgium has become a permanent country of settlement for many different types of migrants. Our updated Belgium profile delves into modern migration flows and policies in Belgium which are inching away from a piecemeal approach towards a well-needed, long-term strategy.
Once known for large-scale emigration, Greece has become the main point of entry for unauthorized migrants heading toward Europe. The country must now — amid economic turmoil — grapple with issues related to its highly porous borders, mounting asylum applications, and inadequate immigrant-detention system.
Recent Activity
This report analyzes the importance of human capital to the development of London's Tech City and sets this discussion in a broader framework linking cities, digital sectors, and highly skilled immigration. Skilled migrants can play critical roles in economic development in high-tech clusters, but policies sometimes make it difficult for firms to make the most of immigration.
This report explores the accelerating trend in the United Kingdom of mainstreaming of immigrant integration, in which policymakers seek to reach people with a migration background through needs-based social programming and policies that also target the general population. The report has particular focus on policies and programs used in London and Glasgow.
While cities and regions experience both the positive and negative effects of immigration firsthand, they are typically at arm's length, at best, from the policy reins that enable and shape these movements. Immigration policies are rarely calibrated to regional, let alone local, needs. This Transatlantic Council on Migration Statement examines how policymakers at all levels can work together to get more out of immigration.
In the coming weeks, the President-Elect of the European Commission and leaders of the European Union will discuss the new institutional map of the European Union, including new portfolios for the incoming college of Commissioners. Despite the fact that immigration is a critical challenge for the European Union, it has become harder for EU institutions to forge a strong policy. Perhaps as a result of this disconnect, one of the key ideas on the table is to create a Commissioner for Migration.
The global economic crisis and changing migration patterns in Europe bring up questions about how well immigrants are able to find employment and progress into better jobs over time. This overview report caps a series of six country case studies evaluating the employment outcomes for foreign-born workers during their first decade in the Czech Republic, France, Germany, Spain, Sweden, and the United Kingdom.
The European Council's new strategic guidelines, which set the pathway for future policy development in the area of Justice and Home Affairs in the coming years, seem unfeasibly insulated from today's migration and asylum realities and challenges confronting the European Union. The draft represents a missed opportunity to lead EU heads of state forward on critical issues in this area, MPI Europe's Director writes in this commentary.
This MPI Europe telebriefing, releasing the brief "Strengthening Refugee Protection and Meeting Challenges: The European Union's Next Steps on Asylum," examines Europe's current reality with respect to migration and asylum and assesses the possibilities for future development of EU immigration policy.
With the European Council meeting in late June 2014 to adopt strategic guidelines on asylum and migration policy, amid strains resulting from Syrian refugee migration and other flows, this MPI Europe policy brief identifies challenges and proposes a forward course. The brief recommends increased engagement by Member States in practical cooperation as a way to strengthen implementation and consolidation of existing EU laws and achieve more consistent asylum decision-making.


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VA moves mobile from concept to reality with veteran homelessness app
Thursday - 1/24/2013, 7:07am EST
Dave Peters, assistant deputy CIO for development management, VA
In the eight months since the Office of Management and Budget released the Digital Government Strategy, agencies have been busy putting the building blocks in place to incorporate and innovate with mobile computing.
For instance, the Homeland Security Department published in August the security baseline framework, and it plans on releasing part two later this spring.
The Chief Information Officer's Council issued a bring-your-own-device (BYOD) guidance for agencies to consider as they move toward this new approach to smartphones and tablets.
But the real impact of the Digital Government Strategy isn't any guidance or document, but how agencies use the concepts to respond to mission needs. And there may be no better example of that impact than what the departments of Veterans Affairs and Housing and Urban Development did over the last two weeks.
VA and HUD created a mobile application to make it easier for employees to count homeless veterans as part of their annual point-in-time survey.
"During the last two weeks of January, starting now, they will be out in the field with this application in some cases, this is really a pilot, to use this application to collect some basic demographic information using the geolocator on the iPhone to find out what your location is when possible," said Dave Peters, VA's assistant deputy CIO for development management, at the Federal Mobile Computing Summit Wednesday in Washington. "The data will be stored on the phone temporarily until cellular coverage is reestablished and then sent off to the VA database."
Peters said VA and HUD not only developed the app, but got it through all the major hurdles so it could be deployed in time for the two-week survey.
"We had the right customer, very engaged. The pressure helped I think in this case. Without a lot of time to argue, things get done," he said. "We also had great support from our management structure, our leadership through [Assistant Secretary in the Office of Information and Technology and CIO] Roger Baker, and their willingness to get engaged and support the waivers in the cases where we needed it."
Spurring innovation through mobile
The approach VA and HUD took shows the beginnings of the necessary culture change to do what the Obama administration has been pushing for, to innovate and do more with less through mobile.
"What are we doing to spur innovation? We set standards for agencies to take off and run," said Lisa Schlosser, the federal deputy CIO. "We published in May the Digital Government Strategy, which we believe is forward thinking and leaning. It sets out the way we will approach digital government."
The document laid out multiple milestones over three, six and 12 month timeframes. Each goal adds another brick down the path toward easing the process to create apps and use mobile devices.
"There's been a lot of collaboration around mobile security, and now we have a more common understanding how we talk about mobile security, the risks in the mobile environment and how we can tailor those risks to our mission," said Rick Holgate, CIO at the Bureau of Alcohol, Tobacco, Firearms and Explosives inside the Justice Department. "We've also seen an emphasis on adopting common platforms across agencies."
VA is trying to adopt not only common platforms, but a standard approach mobile app development.
Peters said the work with HUD shows what the future path could look like.
"I would very much like more apps done in this manner, when appropriate. We were under tremendous pressure to get this out in such a short period of time that I couldn't imagine this working in any other way. If you wanted to talk about developing a business requirement, for instance, the entire two weeks would've been eaten up by that alone. It would have been impossible to develop something like this in that manner."
New governance model at VA
To continue moving down the path laid by their work with HUD, VA is developing a new governance model for mobile applications. The Veterans Health Administration (VHA) and the CIO's office are creating a joint governance board to manage the mobile apps development process.
Peters said this is not a board to oversee pilot programs with mobile devices, but the actual software development process.
"In the past, only OIT and product development would be allowed to develop applications. We recognized that in this current environment we want to use any resources we can, and working with VHA, who has a great interest in developing mobile apps and resources, we created this joint board," he said. "Eventually, it will include Veterans Benefits Administration and the Cemeteries Administration as well. We are just getting started in the talks, working through the initial documentation, putting together an integrated project team to review the documents, and eventually all mobile apps regardless of the source will come through this organization."


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The only reason I gave it 4/5 stars is that I didn't care too much for the smell. It was...interesting, just not for me.posted Jan 14, 2011Link to this post -
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JaymeeCAReally WorksI had to wait so long for this product to arrive but it was worth the wait. I straighten my hair about 3 times a week and do touch ups in between and my ends have taken a lot damage. They were brittle and hard so i decided to try this deep conditioner and it really is amazing. It leaves my dry and damaged hair feeling really soft. I leave it on for a while and sometimes wrap my hair up in a towel while i have it on and it has turned out to be great.posted Sep 1, 2008Link to this post
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I'm Melinda, founder of Kitchen-Tested.com. After my two young children go to bed, the pots and pans come out and the escapades begin. I hope to inspire you by adding unique twists to simple recipes and bravely using unusual ingredients in an accessible way.
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Home > Electronics & Gadgets > USB Hubs, Drives & Accessories >
The Doctor goes Christmas shopping!
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REVIEW: Kick-Ass 2
The best part of "Kick-Ass 2": Chloe Grace Moretz. You can't take your eyes off this girl. She's one of the best of "yout"
The movie is at its height when it's comic-booky and ironic. The anti-bullying theme with Hit Girl taking on the mean girls of high school is priceless. But as a whole, the movie just isn't fun , fresh and shocking – who can forget the mouth on the younger Hit Girl??!!
This one's meaner, nastier and worse, uber bloody. Not in a pulpy way . I can understand why Jim Carrey didn't want to promote his own movie. Some of the violence had me cringing at the thought of 14 year olds seeing this- because that's exactly who will want to see this film.
1-and-a-half stars


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The best place to ask and answer questions about development with Unity.
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Gojira & Kvelertak Back Out On Tour With Mastodon July 07, 2014 7:18:43 PM UTC Tickets go on sale this week for the second leg of the tour
Empress AD to release Still Life Moving Fast September 2nd July 07, 2014 5:20:09 PM UTC Empress AD's debut album is available to pre-order now
SLIPKNOT'S LEGENDARY KNOTFEST RETURNS July 07, 2014 2:44:22 PM UTC Friday October 24th through Sunday October 26th in San Bernadino, CA
Behind The Scenes Of Savages Pt. 2 July 02, 2014 12:57:14 PM UTC We have another exclusive behind the scenes look at Theory Of A Deadman's fifth album
Pre-Order Memoirs Of A Murderer July 01, 2014 3:53:35 PM UTC KING 810's debut album available for pre-order now!
KING 810's 'Fat Around The Heart' Premieres on Alt Press July 01, 2014 2:08:51 PM UTC Alternative Press debuted KING 810's video for 'Fat Around The Heart'
Theory Of A Deadman - Savages June 26, 2014 3:28:58 PM UTC Check out the official lyric video for Theory of a Deadman's "Savages"


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hi all
My name is Zim, nice to meet you. I don't speak english well but thx for the good job. See you soon
New.. hey everybody
Last edited by VJAssassin; 07-10-2012 at 12:06 PM Reason: Automerged Doublepost
I'm new but I have been looking at the forums for a while and I just decided to join.
I also have a 3.55 KMEAW CFW PS3 and can go online with it. I do host MW2 CL's.
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