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Showing 1-24 of 96 items found in Food & Drink
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Grafton Winery & Brewhaus
Located in the quaint river town of Grafton Illinois along the Great River Road Scenic Byway, the Grafton Winery and Brewhaus overlooks the confluence of the Mississippi and Illinois Rivers. Nestled among the river bluffs, our winery offers great views of the river for every season. Come join us for dinner with soup, salads, sandwiches, burgers, and pasta dishes. Private parties & banquets are welcome.
Mac's Time-Out Lounge/Off Track Betting
Order off the extensive menu. Why not try the real Southern-style chicken and dumplings or meat-lover's pizza? You'll find fair prices, large portions & excellent dishes. Try eating outside at the comfortable terrace-style beer garden. Your whole family will have a pleasant dining experience. Place your bets at the off-track betting parlor. Stay late for a cold one.
Fast Eddie's Bon Air
Fast Eddie's Bon Air in Alton is like no other. Over 4,000 half barrels of beer and thousands of cases of cans, bottles and liquor quench the thirst of our patrons every year. Some even say that Bon Air is the #1 volume bar in the world. A food bar serves an assortment of grilled burgers, shish-kabobs, bratwurst and boiled shrimp all sold at the same low prices as when they were added nineteen years ago.
Aerie's Riverview Winery
The view is incredible and the wine selection is unbeatable every season of the year on top of the bluffs at Aerie's Winery. During the spring and summer, the outdoor deck offers a breathtaking view of recreation on the river. As the temperatures cool, you can lounge inside next to the fireplace. Aerie's also offers cottages and a lodge to accommodate the needs of overnight guests, all within walking distance of the winery. Seasonally, check our calendar for live music on the decks Wine, cheese, sausages and pizza are available.
My Just Desserts
Follow the lead of the locals in Alton and order dessert first, at My Just Desserts, as fresh-baked favorites like the Tollhouse brownies and Mrs. Ledbetter's chocolate pie sell out early. Every morning 9 to 13 pie varieties are baked fresh. You'll swear you stepped back in time when you enter this unique establishment, from the squeak in the hardwood floors to the Mason jar glasses.
Argosy Casino - Captain's Table Buffet
Even the heartiest of appetites is no match for the Captain's Table Buffet. Enjoy seasonal favorites, hand-selected by our chefs. From comfort foods like special-recipe fried chicken and mashed potatoes to fresh fish and steamed vegetables we are sure to have exactly what you are looking for.
Piasa Winery & Pub
Wine, beer, food and an amazing view of the Mississippi River are all part of the charm of the Piasa Winery & Pub. Enjoy award-winning wines made at the Piasa vineyards or try one of the more than 400 Illinois and international wines available. Sit on the deck of the riverfront pub and relax with a beer from the more than 100 imported and domestic brews on hand. Appetizers, sandwiches (including the Piasa Pounder -- take the challenge if you dare!) soups, salads, pastas and desserts are available on this full service menu.
Mary Michelle Winery Tasting Room
Enjoy award-winning wines at Mary Michelle Winery located at Pere Marquette Lodge, in scenic Pere Marquette State Park. The Tasting Room, Fountain Patio and Riverview Terrace are the perfects spots to relax with a glass of wine and unwind. Mary Michelle wines include Norton, Chardonel and Moscato. The winery is open 2 p.m. - 8 p.m. daily.
Tony's Restaurant
Family owned for more than 50 years, Tony's is located in Alton on Third Street. Known for their mouth-watering pepperloin steaks, the family recipe has been a crowd pleaser for years. Homemade pastas and family recipes make for a memorable meal. Tony's offers the best of both worlds with a formal dining room, perfect for a romantic meal or to celebrate a special occasion. The Third Street Cafe entrance features a sports bar atmosphere perfect for kicking back to enjoy a slice of fresh secret recipe pizza, a juicy half-pound steakburger or a basket of wings. From casual family dining to a cozy meal together, Tony's is your place!
Bubby and Sissy's
Located just a few blocks from the riverfront Argosy Casino Alton, this bar hosts drag shows every weekend, karaoke on Thursdays, amateur drag queen and king shows the last Wednesday of the month, and dancing to DJ-driven music.
Pere Marquette Lodge Restaurant
Enjoy family-style dining in a rustic setting at the Pere Marquette Lodge dining room. The Lodge is famous for its family-style fried chicken and fried catfish dinners. You won't leave the table hungry at all! Seasonally, the Lodge offers a brunch buffet on Sundays with everything from made-to-order omelets to baked ham and fried chicken. There is something for everyone. Hours: Sunday - Thursday, 7 a.m. - 8 p.m., and Friday - Saturday, 7 a.m. - 9 p.m.
Two Rivers Winery
Bring a picnic lunch and Two Rivers Winery in historic Grafton will supply the wine or beer! Featured wineries include Hopewell Winery and Villa Maria Winery, although a variety of Illinois wines are available including Alto Vineyards, Von Jakob and St. James. Micro-brew beers, seasonal beers and four draft beers are on tap. In case you forgot your picnic basket, Two Rivers Winery offers cheeses, sausage and crackers in addition to 6 and 12-inch pizzas. Two Rivers Winery has indoor and outdoor seating that features a great river view. Hours: Wednesday, Thursday, & Sunday 11 a.m. - 7 p.m. and Friday - Saturday, 11 a.m. - 11 p.m.
Loading Dock
Sit back, sip your drink and enjoy the serenity of the Mississippi River as it flows past The Loading Dock Bar and Grill in Grafton, Illinois at the confluence of the Mississippi and Illinois rivers. Like being on vacation, it's the only place like it where you can sit by the water and watch the boat traffic on the river while enjoying stunning views of the palisades. Bring the kids along by day or at night, listen to live music while enjoying a full menu of hot fresh food served right off the grill. Make sure you begin your meal munching on a basket of chips dipped in the famous Dock Salsa!
Josephine's Tea Room
Enjoy a Girls' Day Out with lunch at Josephine's Tea Room in Godfrey. Fresh salads, soups, sandwiches and desserts made daily highlight the menu. While at the tea room, browse the many gift shops on the complex, including Josephine's Gifts, the Monticello House, Fred's Shed featuring discounted merchandise and the new Christmas House. Jospehine's is the perfect stop for a girls' day out shopping and having fun. Hours: M -F 11 a.m. - 2 p.m., S 11 a.m. - 3 p.m. Open on Sundays in December 11 a.m.- 3 p.m.
Riverbend Billiards & Grill
Riverbend Billiards provides 10,000 sq. ft. of entertainment. There is great food and beverages for everyone, plus a full bar for our over 21 crowd. You'll find 15 7-ft. bar tables and two 9-ft. Gold Crowns. Dart machines and video games are available for the kids. Riverbend Billiards sells a wide variety of pool cues, cases and miscellaneous pool supplies as well as a large selection of soft tip darts and dart supplies.
Fin Inn
Watch the fish swim in four 2,000 gallon aquariums as you enjoy one of the Fin Inn's signature catfish, Alaskan White Fish, or frog leg dinners. Adults and kids alike love to watch the fish swim in the aquariums with 21 table-side aquarium-viewing windows. Enjoy a full menu of fried fish, home-style meals and a local favorite - turtle soup! Children's menu available. Hours: 11 a.m. - 9 p.m.
Crazy Beaver Pizza Lodge
Hungry after a day shopping and seeing the sights in Grafton? Then stop by the Crazy Beaver Lodge for a hand-tossed fresh pizza made with the toppings of your choice. On Fridays only, you can buy a 5 pound deep dish pizza which is sure to satisfy even the biggest pizza lover in your crew. Sandwiches, salads and appetizers are also available. Live music on Sundays. Hours: W - F 4 p.m. - 10 p.m. S - Su 11 a.m. - 10 p.m.
The Whole Scoop
Imagine a life boat made out of a mint chip fudge brownie, covered in strawberry ice cream and topped with chocolate sauce, whipped cream and a cherry. That's The Whole Scoop's newest version of their signature sundae called the "Life Boat". And it's not just sweet treats at The Whole Scoop. From secret recipe marinated chicken in the Chipotle Chicken Wrap to Mom's Recipe Chili, great homemade eats abound. Located in historic downtown Grafton, The Whole Scoop is a great place to stop during a day of shopping and river watching. Hours: 11 a.m. - 7 p.m. daily.
Chocolate Air
Imagine a store filled with chocolate - chocolate turtles, carmels, cupcakes and tiered cakes. Add in a dash of antiques and collectibles and you have Chocolate Air in Godfrey. This homey store makes all its chocolate creations from scratch so they are sure to delight. Don't leave without trying their three signature confections: Turtles, Chocolate Covered Bacon and Chocolate Covered Strawberries. Hours: Tuesday - Friday, 10 a.m. - 6 p.m. and Saturday, 10 a.m. - 5 p.m.
Argosy Casino - Outfitter's Grill
A breathtaking view of the Upper Mississippi and the Clark Bridge is the perfect complement to an Outfitters Grill menu that has prime cuts of USDA Choice beef, the freshest seafood, mouthwatering pasta and so much more.
Panera Bread
Every day, trained bakers craft and bake loaves of bread from scratch, using the best ingredients to ensure the highest quality breads. Panera Bread understands that great bread makes great meals, from made-to-order sandwiches to tossed-to-order salads and soup served in bread bowls.
Clifton Country Inn & Bake Shop
If its biscuits and gravy you crave, then Clifton Country Inn & Bake Shop is the place to go in Godfrey. In addition to traditional bakery goods like donuts, this family-owned diner also features a full breakfast and lunch menu. There are also daily lunch specials. Hours: Monday - Friday, 6 a.m. - 8 p.m. and Saturday - Sunday, 6 a.m. - 3 p.m.
Mary Michelle Winery
Mary Michelle has 60 acres of vineyards adjacent to the winery and grows most of the grapes that it uses for its wines. This Winery sells only through stores and restaurants. Mary Michelle's winemaker is the award-winning Lucian Dressel, a fifth generation Greene County resident by way of Boston, New York, Augusta, Mo., and Davis, Ca. In 2003, inspired by the vision of the founders of Mary Michelle, Dressel returned to the Midwest to help make a contribution to the fulfillment of this dream.


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Rosacea Center - West Covina, CAWest Covina Dermatologist Doctors for RosaceaType of Physician: Dermatologist What is a Dermatologist? A certification by the Board of Dermatology; practitioners treat pediatric and adult patients with disorders of the skin, mouth, hair and nails as well as a number of sexually transmitted diseases. They also have expertise in the care of normal skin, the prevention of skin diseases and cancers, and in the management of cosmetic disorders of the skin such as hair loss and scars. Specialty: Dermatology Common Name: Skin Doctor Dermatologist Doctors in West Covina *West Covina Medical Group Marc Medical Group Richard H Chu MD Inc Magan Medical Clinic Magan Medical Clinic Kaiser Permanente Medical Group Boston Dermatology Laser Dermatology Institute-CA American Dermatology American Dermatology American Dermatology Irene O Lao MD Jen Yee Shen MD John H Wu MD Laurie M Woll DO Advanced Dermatology Advanced Dermatology Laurie M Woll DO Glendora Dermatologic/Cosmetic Kaiser Permanente Dermatology Healthcare Partners Medical Grp Dong L Chang MD Inc Dong L Chang MD Inc Dong L Chang MD Inc David A Voron MD Inc Center For Advanced Dermatology Center For Advanced Dermatology Healthcare Partners Medical Grp Country Hills Laser Medical Ctr Foothill Dermatology/Aesthetics Foothill Dermatology/Aesthetics Preferred Dermatology Preferred Dermatology Preferred Dermatology Gene J Lin MD Caremore Medical Group Fortunata L Mendoza MD PIH Health PIH Health Sid A Danesh MD Obagi Dermatology Medical Clini Premiere Dermatology/Laser Ctr St Jude Heritage Med Grp Derm Charles Salinger MD St Jude Heritage Med Grp Derm St Jude Heritage Med Grp Derm Accredited Dermatology Advanced Skin Cr Sgy Ctr Advanced Skin Cr Sgy Ctr Accredited Dermatology Advanced Skin Cr Sgy Ctr Saint Jude Heritage Med Grp Aston & Baugh MDs Aston & Baugh MDs Cindy X Shu MD Kuan-Wen Su MD Robert C Wang MD Inc ABC Medical Clinic Lopansri & Lopansri Mds Lawrence M Schall MD Julie A Hodge MD PC Sue Patt MD Inc Healthcare Partners Medical Grp Yorba Linda Dermatology St Jude Heritage Medical Group Inland Empire Medical Network Chaparral Medical Group Bruce S Park MD West Dermatology Telegraph Dermatology Pasadena Premiere Dermatology West Dermatology Pasadena Premiere Dermatology Pasadena Premiere Dermatology Violeta M Navasardian MD Inc Pasadena Premiere Dermatology Advanced Laser/Anti Aging Med West Dermatology Alexander Miller MD James R Esther MD Rigor Dermatology & Laser Ctr Bennett Surgery Center Comprehensive Dermatology Healthcare Partners Med Grp Healthcare Partners Med Grp Comprehensive Dermatology Comprehensive Dermatology Healthcare Partners Med Grp Paul J Mcandrews MD Comprehensive Dermatology Comprehensive Dermatology Bennett Surgery Center Healthcare Partners Med Grp Rejuvayou Huntington Dermatology Group Drange Hallman Medical Corp Huntington Dermatology Group Rejuvayou Huntington Dermatology Group Talbert Medical Group West Covina, CaliforniaRosaceaRosacea facts
Emergency Contact for West Covina
Nearby West Covina Hospitals *Doctors Hospital Of West Covina Citrus Valley Medical Center Kindred Hospital Kaiser Permanente Medical Ctr Citrus Valley Medical Center Aurora Charter Oak Hospital City Of Hope National Med Ctr East Valley Hospital Med Ctr Foothill Presbyterian Hospital Greater El Monte Community Hosp San Dimas Community Hospital Methodist Hospital Southern CA Lanterman Developmental Center BHC Alhambra Hospital American Recovery Center Whittier Hospital & Medical Ctr Presbyterian Intercommunity Silver Lake Medical Center San Gabriel Valley Medical Ctr Aurora Las Encinas Hospital Kindred Hospital-Brea Beverly Hospital Garfield Medical Center Landmark Medical Center Pomona Valley Hospital Med Ctr Casa Colina Hospital For Rehab Kindred Hospital La Mirada Monterey Park Hospital Alhambra Hospital Medical Ctr Metropolitan State Hospital St Jude Medical Center Huntington Memorial Hospital Norwalk Community Hospital Montclair Hospital Medical Ctr Placentia Linda Hospital Anaheim General Hospital Impact Drug & Alcohol Treatment Coast Plaza Hospital East Los Angeles Doctors Hosp Los Angeles Community Hospital Downey Regional Medical Center Chino Valley Medical Center Canyon Ridge Hospital Keck Hospital Of USC USC Kenneth Norris Cancer Ctr Kaiser Permanente Medical Ctr Anaheim Regional Medical Center California Institution For Men LAC USC Medical Center Promise Hospital College Hospital Cerritos Orange Cnty Anaheim Med Cntr Rancho Los Amigos Hospital White Memorial Medical Center La Palma Intercommunity Hosp Los Angeles Sheriff's Dept Med Kindred Hospital Ontario Lapaz At Paramount Pacific Alliance Medical Center Community Hospital Huntngtn Prk San Antonio Community Hospital Kaiser Mental Health Center West Anaheim Medical Center Bellflower Medical Center Glendale Adventist Medical Ctr Western Medical Center Anaheim Barlow Respiratory Hospital Anaheim General Hospital Gateways Hsptl & Mntl Hlth St Francis Medical Center Promise Hospital Of East LA Verdugo Hills Hospital Tri-City Regional Medical CT Glendale Memorial Hospital Silver Lake Medical Center *Provider Directory Terms of Use: The WebMD 'Provider Directory' is provided by WebMD for use by the general public as a quick reference of information about Providers. The Provider Directory is not intended as a tool for verifying the credentials, qualifications, or abilities of any Provider contained therein. Inclusion in the Provider Directory does not imply recommendation or endorsement nor does omission in the Provider Directory imply WebMD disapproval. |

subset: commoncrawl


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- nutlin-3 (2)
- p53 (2)
- Diagnostics (1)
- Ehrlich (1)
- Frankfurt (1)
- Frankfurt <Main> / Paul-Ehrlich-Institut (1)
- Inhibition of apoptosis prevents West Nile virus induced cell death (2007)
- Background: West Nile virus (WNV) infection can cause severe meningitis and encephalitis in humans. Apoptosis was recently shown to contribute to the pathogenesis of WNV encephalitis. Here, we used WNV-infected glioma cells to study WNV-replication and WNV-induced apoptosis in human brain-derived cells. Results: T98G cells are highly permissive for lytic WNV-infection as demonstrated by the production of infectious virus titre and the development of a characteristic cytopathic effect. WNV replication decreased cell viability and induced apoptosis as indicated by the activation of the effector caspase-3, the initiator caspases-8 and -9, poly(ADP-ribose)polymerase (PARP) cleavage and the release of cytochrome c from the mitochondria. Truncation of BID indicated cross-talk between the extrinsic and intrinsic apoptotic pathways. Inhibition of the caspases-8 or -9 inhibited PARP cleavage, demonstrating that both caspases are involved in WNV-induced apoptosis. Pancaspase inhibition prevented WNV-induced apoptosis without affecting virus replication. Conclusions: We found that WNV infection induces cell death in the brain-derived tumour cell line T98G by apoptosis under involvement of constituents of the extrinsic as well as the intrinsic apoptotic pathways. Our results illuminate the molecular mechanism of WNV-induced neural cell death.
- Weltweiter SARS-Alarm : eine neue Seuche auf dem Vormarsch? (2004)
- Mitte März 2003 löste die WHO einen weltweiten Alarm aus, nachdem sich eine neuartige, schwere und unter bestimmten Umständen hochansteckende Atemwegserkrankung scheinbar unaufhaltsam über weite Teile der Welt auszubreiten schien. Am 15. März desselben Jahres landeten die ersten Patienten mit Verdacht auf Schweres Akutes Respiratorisches Syndrom (SARS) in Frankfurt und wurden auf die Isolierstation des Universitätsklinikums aufgenommen. Auslöser war ein zuvor nicht bekanntes Coronavirus, das heute als SARS-CoV bezeichnet wird. Derzeit laufen Untersuchungen zur Biologie und Epidemiologie des neuen Erregers, zu antiviralen Hemmstoffen sowie zu Desinfektions- und Inaktivierungsmöglichkeiten und neuen Therapieoptionen. Daneben wird analysiert, wie sich das öffentliche Gesundheitswesen auf eine mögliche Wiederkehr vorbereiten muss. SARS ist ein Beispiel dafür, wie schnell sich eine Infektionskrankheit in der modernen Welt international ausbreiten kann und wie wichtig in einem solchen Falle eine gut koordinierte internationale Kooperation ist. Frankfurter Forscher berichten.
- Chemoresistance induces enhanced adhesion and transendothelial penetration of neuroblastoma cells by down-regulating NCAM surface expression (2006)
- Background Drug resistance to chemotherapy is often associated with increased malignancy in neuroblastoma (NB). One explanation for the link between resistance and malignancy might be that resistance facilitates cancer progression and invasion. To investigate this hypothesis, adhesion, transendothelial penetration and NCAM (CD56) adhesion receptor expression of drug-resistant versus drug-sensitive NB tumor cells were evaluated. Methods Acquired drug resistance was mimicked by exposing parental UKF-NB-2, UKF-NB-3 or IMR-32 tumor cells to increasing concentrations of vincristine- (VCR) or doxorubicin (DOX) to establish the resistant tumor cell sublines UKF-NB-2VCR, UKF-NB-2DOX, UKF-NB-3VCR, UKF-NB-3DOX, IMR-32VCR and IMR-32DOX. Additionally, the malignant behaviour of UKF-NB-4, which already possessed the intrinsic multidrug resistance (MDR) phenotype, was analyzed. UKF-NB-4 exposed to VCR or DOX were designated UKF-NB-4VCR or UKF-NB-4DOX. Combined phase contrast - reflection interference contrast microscopy was used to separately evaluate NB cell adhesion and penetration. NCAM was analyzed by flow cytometry, western blot and RT-PCR. Results VCR and DOX resistant tumor sublines showed enhanced adhesion and penetration capacity, compared to their drug naive controls. Strongest effects were seen with UKF-NB-2VCR, UKF-NB-3VCR and IMR-32DOX. DOX or VCR treatment also evoked increased invasive behaviour of UKF-NB-4. The process of accelerated tumor invasion was accompanied by decreased NCAM surface and protein expression, and down-regulation of NCAM coding mRNA. Transfection of UKF-NB-4VCR cells with NCAM cDNA led to a significant receptor up-regulation, paralleled by diminished adhesion to an endothelial cell monolayer. Conclusions It is concluded that NB cells resistant to anticancer drugs acquire increased invasive capacity relative to non-resistant parental cells, and that enhanced invasion is caused by strong down-regulation of NCAM adhesion receptors.
- Human monoclonal antibody combination against SARS coronavirus : synergy and coverage of escape mutants (2006)
- Background: Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible. For an effective immune prophylaxis in humans, broad coverage of different strains of SARS-CoV and control of potential neutralization escape variants will be required. Combinations of virus-neutralizing, noncompeting mAbs may have these properties. Methods and Findings: Human mAb CR3014 has been shown to completely prevent lung pathology and abolish pharyngeal shedding of SARS-CoV in infected ferrets. We generated in vitro SARS-CoV variants escaping neutralization by CR3014, which all had a single P462L mutation in the glycoprotein spike (S) of the escape virus. In vitro experiments confirmed that binding of CR3014 to a recombinant S fragment (amino acid residues 318–510) harboring this mutation was abolished. We therefore screened an antibody-phage library derived from blood of a convalescent SARS patient for antibodies complementary to CR3014. A novel mAb, CR3022, was identified that neutralized CR3014 escape viruses, did not compete with CR3014 for binding to recombinant S1 fragments, and bound to S1 fragments derived from the civet cat SARS-CoV-like strain SZ3. No escape variants could be generated with CR3022. The mixture of both mAbs showed neutralization of SARS-CoV in a synergistic fashion by recognizing different epitopes on the receptor-binding domain. Dose reduction indices of 4.5 and 20.5 were observed for CR3014 and CR3022, respectively, at 100% neutralization. Because enhancement of SARS-CoV infection by subneutralizing antibody concentrations is of concern, we show here that anti-SARS-CoV antibodies do not convert the abortive infection of primary human macrophages by SARS-CoV into a productive one. Conclusions: The combination of two noncompeting human mAbs CR3014 and CR3022 potentially controls immune escape and extends the breadth of protection. At the same time, synergy between CR3014 and CR3022 may allow for a lower total antibody dose to be administered for passive immune prophylaxis of SARS-CoV infection.
- Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells (2009)
- Background Chemoresistance acquisition may influence cancer cell biology. Here, bioinformatics analysis of gene expression data was used to identify chemoresistance-associated changes in neuroblastoma biology. Results Bioinformatics analysis of gene expression data revealed that expression of angiogenesis-associated genes significantly differs between chemosensitive and chemoresistant neuroblastoma cells. A subsequent systematic analysis of a panel of 14 chemosensitive and chemoresistant neuroblastoma cell lines in vitro and in animal experiments indicated a consistent shift to a more pro-angiogenic phenotype in chemoresistant neuroblastoma cells. The molecular mechanims underlying increased pro-angiogenic activity of neuroblastoma cells are individual and differ between the investigated chemoresistant cell lines. Treatment of animals carrying doxorubicin-resistant neuroblastoma xenografts with doxorubicin, a cytotoxic drug known to exert anti-angiogenic activity, resulted in decreased tumour vessel formation and growth indicating chemoresistance-associated enhanced pro-angiogenic activity to be relevant for tumour progression and to represent a potential therapeutic target. Conclusions A bioinformatics approach allowed to identify a relevant chemoresistance-associated shift in neuroblastoma cell biology. The chemoresistance-associated enhanced pro-angiogenic activity observed in neuroblastoma cells is relevant for tumour progression and represents a potential therapeutic target.
- Immunity status of adults and children against poliomyelitis virus type 1 strains CHAT and Sabin (LSc-2ab) in Germany (2010)
- Background In October 2007, the working group CEN/TC 216 of the European Committee for standardisation suggested that the Sabin oral poliovirus vaccine type 1 strain (LSc-2ab) presently used for virucidal tests should be replaced by another attenuated vaccine poliovirus type 1 strain, CHAT. Both strains were historically used as oral vaccines, but the Sabin type 1 strain was acknowledged to be more attenuated. In Germany, vaccination against poliomyelitis was introduced in 1962 using the oral polio vaccine (OPV) containing Sabin strain LSc-2ab. The vaccination schedule was changed from OPV to an inactivated polio vaccine (IPV) containing wild polio virus type 1 strain Mahoney in 1998. In the present study, we assessed potential differences in neutralising antibody titres to Sabin and CHAT in persons with a history of either OPV, IPV, or OPV with IPV booster. Methods Neutralisation poliovirus antibodies against CHAT and Sabin 1 were measured in sera of 41 adults vaccinated with OPV. Additionally, sera from 28 children less than 10 years of age and immunised with IPV only were analysed. The neutralisation assay against poliovirus was performed according to WHO guidelines. Results The neutralisation activity against CHAT in adults with a complete OPV vaccination series was significantly lower than against Sabin poliovirus type 1 strains (Wilcoxon signed-rank test P < 0.025). In eight sera, the antibody titres measured against CHAT were less than 8, although the titre against Sabin 1 varied between 8 and 64. Following IPV booster, anti-CHAT antibodies increased rapidly in sera of CHAT-negative adults with OPV history. Sera from children with IPV history neutralised CHAT and Sabin 1 strains equally. Conclusion The lack of neutralising antibodies against the CHAT strain in persons vaccinated with OPV might be associated with an increased risk of reinfection with the CHAT polio virus type 1, and this implies a putative risk of transmission of the virus to polio-free communities. We strongly suggest that laboratory workers who were immunised with OPV receive a booster vaccination with IPV before handling CHAT in the laboratory.
- Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression (2011)
- Glycyrrhizin is known to exert antiviral and anti-inflammatory effects. Here, the effects of an approved parenteral glycyrrhizin preparation (Stronger Neo-Minophafen C) were investigated on highly pathogenic influenza A H5N1 virus replication, H5N1-induced apoptosis, and H5N1-induced pro-inflammatory responses in lung epithelial (A549) cells. Therapeutic glycyrrhizin concentrations substantially inhibited H5N1-induced expression of the pro-inflammatory molecules CXCL10, interleukin 6, CCL2, and CCL5 (effective glycyrrhizin concentrations 25 to 50 µg/ml) but interfered with H5N1 replication and H5N1-induced apoptosis to a lesser extent (effective glycyrrhizin concentrations 100 µg/ml or higher). Glycyrrhizin also diminished monocyte migration towards supernatants of H5N1-infected A549 cells. The mechanism by which glycyrrhizin interferes with H5N1 replication and H5N1-induced pro-inflammatory gene expression includes inhibition of H5N1-induced formation of reactive oxygen species and (in turn) reduced activation of NFKappaB, JNK, and p38, redox-sensitive signalling events known to be relevant for influenza A virus replication. Therefore, glycyrrhizin may complement the arsenal of potential drugs for the treatment of H5N1 disease.
- Selection of a highly invasive neuroblastoma cell population through long-term human cytomegalovirus infection (2012)
- The human cytomegalovirus (HCMV) is suspected to increase tumour malignancy by infection of cancer and/or stroma cells (oncomodulation). So far, oncomodulatory mechanisms have been attributed to the presence of HCMV and direct action of its gene products on cancer cells. Here, we investigated whether the prolonged presence of HCMV can result in the irreversible selection of a cancer cell population with increased malignancy. The neuroblastoma cell line UKF-NB-4 was long-term (200 passages) infected with the HCMV strain Hi91 (UKF-NB-4Hi) before virus eradication using ganciclovir (UKF-NB-4HiGCV). Global gene expression profiling of UKF-NB-4, UKF-NB-4Hi and UKF-NB-4HiGCV cells and subsequent bioinformatic signal transduction pathway analysis revealed clear differences between UKF-NB-4 and UKF-NB-4Hi, as well as between UKF-NB-4 and UKF-NB-4HiGCV cells, but only minor differences between UKF-NB-4Hi and UKF-NB-4HiGCV cells. Investigation of the expression of a subset of five genes in different chronically HCMV-infected cell lines before and after virus eradication suggested that long-term HCMV infection reproducibly causes specific changes. Array comparative genomic hybridisation showed virtually the same genomic differences for the comparisons UKF-NB-4Hi/UKF-NB-4 and UKF-NB-4HiGCV/UKF-NB-4. UKF-NB-4Hi cells are characterised by an increased invasive potential compared with UKF-NB-4 cells. This phenotype was completely retained in UKF-NB-4HiGCV cells. Moreover, there was a substantial overlap in the signal transduction pathways that differed significantly between UKF-NB-4Hi/UKF-NB-4HiGCV and UKF-NB-4 cells and those differentially regulated between tumour tissues from neuroblastoma patients with favourable or poor outcome. In conclusion, we present the first experimental evidence that long-term HCMV infection can result in the selection of tumour cell populations with enhanced malignancy.
- Oncolytic effects of a novel Influenza A virus expressing Interleukin-15 from the NS reading frame (2012)
- Oncolytic influenza A viruses with deleted NS1 gene (delNS1) replicate selectively in tumour cells with defective interferon response and/or activated Ras/Raf/MEK/ERK signalling pathway. To develop a delNS1 virus with specific immunostimulatory properties, we used an optimised technology to insert the interleukin-15 (IL-15) coding sequence into the viral NS gene segment (delNS1-IL-15). DelNS1 and delNS1-IL-15 exerted similar oncolytic effects. Both viruses replicated and caused caspase-dependent apoptosis in interferon-defective melanoma cells. Virus replication was required for their oncolytic activity. Cisplatin enhanced the oncolytic activity of delNS1 viruses. The cytotoxic drug increased delNS1 replication and delNS1-induced caspase-dependent apoptosis. Interference with MEK/ERK signalling by RNAi-mediated depletion or the MEK inhibitor U0126 did not affect the oncolytic effects of the delNS1 viruses. In oncolysis sensitive melanoma cells, delNS1-IL-15 (but not delNS1) infection resulted in the production of IL-15 levels ranging from 70 to 1140 pg/mL in the cell culture supernatants. The supernatants of delNS1-IL-15-infected (but not of delNS1-infected) melanoma cells induced primary human natural killer cell-mediated lysis of non-infected tumour cells. In conclusion, we constructed a novel oncolytic influenza virus that combines the oncolytic activity of delNS1 viruses with immunostimulatory properties through production of functional IL-15. Moreover, we showed that the oncolytic activity of delNS1 viruses can be enhanced in combination with cytotoxic anti-cancer drugs.


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Japan to fast track Supersonic Airliner
May 10, 2006 The Supersonic Transport Team at the Japanese Aerospace Exploration Agency (JAXA) is reported to be set to begin talks with NASA and Boeing next month with a view to fast-tracking the development of its Scaled Experimental Supersonic Transport (SST) project into a full-blown, next generation Supersonic aircraft which will take over where the retired French-built Concorde left off when it was taken out of service six years ago. Tests of JAXA's scramjet (Supersonic Combustion Ramjet) engine continue (20mb QT movie of lift-off here and 26MB QT movie of flight trial here) with the expectation that the engine can achieve speeds of Mach 5.5 (6700 km/h). Japan is expected to supply the engine for the project with Boeing building the spaceframe.
« Back to Japan to fast track Supersonic Airliner
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Title: No Time To Be Shy
Featuring: Brett Rossi
February 2, 2014


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- Home
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- Fibromyalgia
(FM; Fibromyalgia Syndrome; FMS)
Fibromyalgia Trigger Points |
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- Depression and anxiety
- Chronic headache, such as tension headaches
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Risk Factors
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- Fatigue
- Weakness
- Poor sleep
- Reduced physical endurance
- Problems with concentration, thought, or memory
- Weather changes, especially cold, damp weather
- Stress or anxiety
- Overexertion
- Medical illness
- Surgery
- Widespread pain lasting three months or longer
- Tenderness (on physical exam) in specific areas of the body
Therapy Programs
- Physical therapy
- Heated pool treatments
- Alternative treatments, such as massage , acupuncture , relaxation training , trigger point therapy, biofeedback, and yoga
- Cognitive behavioral therapy (CBT)
Lifestyle Changes
- Eating a healthy diet
- Learning to cope with physical and mental stress
- Maintaining a regular sleep schedule
- Participating in a regular exercise program that includes aerobic activity, strength training, and flexibility exercises. Gentle exercises that may not strain painful areas include walking, biking, and swimming. Talk to your doctor to make sure it is safe for you to start exercising.
- Antidepressants
- Anticonvulsants
- Sedatives
- Muscle relaxants
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Opioids
American College of Rheumatology http://www.rheumatology.org
The American Fibromyalgia Syndrome Association http://www.afsafund.org
The Arthritis Society http://www.arthritis.ca
Fibromyalgia Information and Local Support http://fibromyalgia.ncf.ca
About fibromyalgia. National Fibromyalgia Association website. Available at: http://fmaware.org/site/PageServerded3.html?pagename=fibromyalgia. Accessed August 9, 2013.
Buckhardt CS, Goldenberg D, Crofford L, et al. Guideline for the management of fibromyalgia syndrome pain in adults and children. Glenview (IL): American Pain Society (APS); 2005. as summarized in National Guideline Clearinghouse 2005;19:7298.
Carville SF, Arendt-Nielsen S, Bliddal H, et al. EULAR evidence-based recommendations for the management of fibromyalgia syndrome. Ann Rheum Dis. 2008;67:536-541.
Fibromyalgia. American College of Rheumatology website. Available at: http://www.rheumatology.org/Practice/Clinical/Patients/Diseases%5FAnd%5FConditions/Fibromyalgia.. Accessed August 9, 2013.
Fibromyalgia. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed.ebscohost.com/about/about-us. Updated July 15, 2013. Accessed August 9, 2013.
Fibromyalgia. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: http://www.niams.nih.gov/Health%5FInfo/Fibromyalgia/default.asp. Updated August 2012. Accessed August 9, 2013.
Wierville L. Fibromyalgia: diagnosing and managing a complex syndrome. J Am Acad Nurse Pract. 2012;24(4):184-92.
2/17/2009 DynaMed's Systematic Literature Surveillance https://dynamed.ebscohost.com/about/about-us : Russell IJ, Perkins AT, Michalek JE; Oxybate SXB-26 Fibromyalgia Syndrome Study Group. Sodium oxybate relieves pain and improves function in fibromyalgia syndrome: a randomized, double-blind, placebo-controlled, multicenter clinical trial. Arthritis Rheum. 2009;60:299-309.
4/14/2009 DynaMed's Systematic Literature Surveillance https://dynamed.ebscohost.com/about/about-us : Munguía-Izquierdo D, Legaz-Arrese A. Assessment of the effects of aquatic therapy on global symptomatology in patients with fibromyalgia syndrome: a randomized controlled trial. Arch Phys Med Rehabil. 2008;89:2250-2257.
4/22/2011 DynaMed's Systematic Literature Surveillance https://dynamed.ebscohost.com/about/about-us : Sañudo B, Galiano D, Carrasco L, Blagojevic M, de Hoyo M, Saxton J. Aerobic exercise versus combined exercise therapy in women with fibromyalgia syndrome: a randomized controlled trial. Arch Phys Med Rehabil. 2010;91(12):1838-1843.
4/22/2011 DynaMed's Systematic Literature Surveillance https://dynamed.ebscohost.com/about/about-us : Carson JW, Carson KM, Jones KD, Bennett RM, Wright CL, Mist SD. A pilot randomized controlled trial of the Yoga of Awareness program in the management of fibromyalgia. Pain. 2010;151(2):530-539.
Revision Information
- Reviewer: Rimas Lukas, MD; Brian Randall, MD
- Review Date: 08/2013 -
- Update Date: 05/11/2013 -


text: The Real Estalker reported that this gorgeous beach front home in the Limahuli Valley on the Hawaiian island of Kauai is not only on the market for $17 million, it's owned by Julia Roberts. The actress and her husband are said to have purchased the home for $10 million in 2009. They then hired San Francisco-based architect Greg Warner to remodel the property. You'll notice the home is open and airy, featuring floor-to-ceiling windows with breathtaking views of Mount Kanana and the ocean. The property sits on eight acres and includes a three-bedroom main house, one-bedroom cottage and 400 feet of direct ocean frontage.


text: The National Pressure Ulcer Advisory Panel (NPUAP) recently discounted the price of its revised guidelines 25%. The Quick Reference Guide for Prevention & Treatment now is available for $19 (plus shipping and handling). The Clinical Practice Guideline for Prevention & Treatment can be purchased for $64 (plus shipping and handling). As a member of NPUAP's Advisory Council, APTA and its members are eligible for an additional discount on these publications. For more information and to order copies, click here.


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Top Definition
An unpopular colleague or group member with poor social skills. Easy to recognize as they are obnoxiously loud and quite unattractive. This individual often inteferes with personal space and makes rude and inappropriate gestures with his crotch.
That dick spank takes crazy long bathroom breaks.
That dick spank takes crazy long bathroom breaks.
بواسطة Amix
ديسمبر 23, 2004
1 more definition
A person who is an unbelievably moronic individual. Someone who continuously gets on one's nerves.
Here comes ricky. I can't stand that dickspank.
بواسطة MonCor
اغسطس 27, 2006


text:
HEAT oven to 400°F.
COOK meat with Taco Seasoning Mix as directed on package. Spread onto pizza crust; top with cheese. Place directly on oven rack.
BAKE 8 to 10 min. or until crust is golden brown and cheese is melted.
TOP with lettuce and tomatoes. Crush Taco Shells; sprinkle over pizza. Drizzle with Salsa.


text:
User Score
Generally favorable reviews- based on 270 Ratings
User score distribution:
Positive: 200 out of 270
Mixed: 18 out of 270
Negative: 52 out of 270
Review this album
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Mar 26, 2013álbum muito bom, com uma gentileza incomparável e uma beleza exuberante, Christina Aguilera mostra todo seu potencial com agudos e batidas que podem não agradar muito a critica, mas vão fazer todos ficarem loucos por essa obra prima da RCA.
Nov 19, 2012this is one of the best album Christina Aguilera has made since 2006's back to Basics. She has changed her evolution to keep up with all these other auto tuned artists but her vocals stand out from each track.
Nov 13, 2012
Nov 13, 2012A perfect album, from the sexist woman in the music business. Christina Aguilera goes above and beyond in this amazing album, with her best song ever "Your Body". Pure perfection, from one of America's hottest women. Whoever said she was fat and ugly need to get hit in the head with a brick.
Nov 14, 2012
Nov 14, 2012The voice might have matured a bit but the sassiness behind it is still there. Listenning to this album is a journey. Wish Empty Words was part of the standard edition.
Dec 29, 2012This review contains spoilers, click expand to view.
Nov 13, 2012
Nov 15, 2012The new project of Christina Aguilera has not anything groundbreaking to the music but it fulfills its role well in pop music. Opening with "Lotus Intro" is more than interesting to move to a new song release in Army Of Me for the new Fighter's on duty. Other songs featured are Cease Fire, Around The World and Just a Fool ('m cheering this to be a great single)
Nov 21, 2012This album is flawless. Most of the tracks are fun and up-tempo while others are emotional and touching. Both type of songs are flawless here. Even the "generic" tracks are amazing and beyond perfect because she brings talent to the songs as well. I love the album, definitely my favorite from year 2012 and not only. Great job, Christina Aguilera!
Feb 10, 2013This review contains spoilers, click expand to view.
Nov 13, 2012
Nov 21, 2012Couldn't be more excited for Lotus. So many gems, this album is amazing and I hope X is in full promo/artist mode because it can do so well. I have been playing it non-stop since it leaked and even more after I bought it!
Nov 17, 2012Lotus es un album multifacetico tal y como lo es Christina Aguilera, por lo mismo es un album que entretiene, podemos encontrar desde baladas hasta pop/rock, para cuando estes sentimental o tengas mucha energia... sin duda es un album que lo puedes escuchar y disfrutar sin importar tu estado de animo, hay una cancion para cada momento!
Nov 13, 2012Simply put, this is Aguilera's most well packaged Recording effort to date. A Pop joyride from start to finish with Aguilera's pipes font and center.
Nov 15, 2012
Nov 13, 2012
Nov 13, 2012
Nov 13, 2012Lotus is honesty, courage and quality, best pop album of 2012. Aguilera proves that she's the voice of generation and the princess of reinvention. Also one of the greatest artists in music history
Nov 13, 2012An incredible, spectacular, fresh, clean disc, what mas do they love? It is an incredible disc for this year as all those that it has been extracting, I have to say that Christina Aguilera has a prodigious voice and that for my undoubtedly it is the best of the world.
Nov 13, 2012Lotus is a phenomenal album by Legend X. Vocally, she is above all artists from her generation incl. Beyoncpé, Belly Clarkson & Studlicia. Justin is still king bye.
Nov 13, 2012This record is a MASTERPIECE! Every single track could be released as a single. The beginning track (Lotus intro) excites you & prepares you for the ride that your about to take. That ride is no disappointment, its a ride your going to want to take over and over again! Spectacular A+
Nov 22, 2012With amazing vocals, this album will make you dance, cry, reflect and inspire!
Highlight for "Sing for me", "Your Body", "Best Of Me", "Army of Me" and "Blank Page. -
Nov 13, 2012
Nov 13, 2012
Nov 13, 2012
Nov 13, 2012Having as the worst performances de eletropop ones, Lotus makes well its work: It is the BEST release in 2012, and show a full Aguilera, with all that we love in her.
Dec 7, 2012Well done Christina, one again, you show evolution, change and your never ending voice. For sure, you are the voice of this generation. Thanks for making real and honest music, like you always does.
Nov 14, 2012This review contains spoilers, click expand to view.
Nov 14, 2012El mejor album del 2012 sin dudas, sonido fresco, sin caer en lo generico, la voz de Aguilera esta mejor que nunca! El disco lo tiene todo! Baladas romanticas, canciones cortavenas, canciones que prenderan las pistas de baile,!
Nov 15, 2012Christina Aguilera is the best vocalist in the world and she shows it in this studio album. This record, LOTUS, is a masterpiece. Every single track could be released as a single. Army Of Me, Sing For Me, Blank Page, all the songs have a special message. Christina' vocals and instrumental are amazing, I will recommend LOTUS to all people.
Nov 15, 2012is much better than Bionic and it's soooo smooth,but what i most wish is if ca could loss her weightl lol but i'm still so happy to see XTINA BACK LOL LOTUS RISE!
Nov 15, 2012Lotus definitely is the best album pop of the year! Sing 4 Me and Blank Page is the most beautiful balad of Lotus.. Army of Me and Cease Fire is POWER. Let There Be Love is awesome.. OMG, this albums so **** good! Xtina always made it the best!!! Legendtina is BACK!
Nov 15, 2012This review contains spoilers, click expand to view.
Nov 15, 2012Lotus is a wonderful album. Christina honestly did a great job in her new comeback, of course! The best song is "Cease Fire". It's a great meaning between war and love. When I heard "Lotus Intro" for the first time, I felt like I was in heaven. No doubt, Lotus is by far the best album of the year.
Nov 15, 2012Album incredible, strong songs, the best we can offer for Xtina fans who already admire and for new fans that may arise over time. A blend of good compositions combined the powerful voice of the blonde.
Nov 15, 2012Album incredible, strong songs, the best we can offer for Xtina fans who already admire and for new fans that may arise over time. A blend of good compositions combined the powerful voice of the generation!!!
Nov 16, 2012Love Let There Be Love, Army Of Me, Just A Fool, Lotus Intro, Your Body, Shut Up, Sing For Me and Make The World Move. Christina Aguilera is amazing.
Nov 16, 2012Lotus is a strong album of wonderful songs!! Xtina's vocal with more powerful than ever. Lotus is perfectly composed and produced, deserves all the success in the world.
Nov 16, 2012What to speak of this album? He is simply amazing!! Xtina always brings quality to your album and Lotus was no different. Army of Me is sensational! Blank Page is sweet and exciting!! Surely one of the best albums of the Year
Nov 16, 2012This review contains spoilers, click expand to view.
Nov 16, 2012
Dec 8, 2012Album is so good. I missed this Christina. A mix of fun songs, a few deep ones and great vocals. My favorites are Best Of Me, Just A Fool, Army of Me, Around The World and Red Hot Kinda Love.
Dec 8, 2012
Dec 9, 2012
Dec 8, 2012
Dec 8, 2012Lotus is a new begining for Aguilera and her fans. Songs like "Best Of Me", "Army Of Me", "Blank Page" and "Just A Fool" represents the unbreakable flower that Xtina has become. She will forever be remembered as THE VOICE OF HER GENERATION
Oct 9, 2013Segundo álbum mais honesto da carreira da Aguilera, desde as suas tristezas, alegrias até os deboches a aqueles que tentam a destruir, (sem exito) melhor álbum de 2012.
Jan 14, 2014
Dec 11, 2012Nothing really stands out like the best thing here, Make The World Move, featuring fellow Voice Judge, Cee-Lo Green. [Jan 2013, p.101]
Nov 27, 2012This might not be the golden, triumphant comeback Aguilera had hoped for, but it's pretty close and, let's face it, it's better than most Top 40 music right now.
Nov 20, 2012This vitriol-tsunami of a record misses a chance to connect Aguilera's music with her warm, empathetic TV presence.


text:
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Hi guys! I'm skjuma from italy!
i would like to add i am too new to ps3news - just a wonderful and xtremely helpful site - very smart and helpful group of people !!!
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Showing 1-24 of 123 items found in Events
- Sort by:
5 - 7
Festival of the Vine
Geneva restaurants create an array of specialties under an outdoor tent at the "Flavor Fare" partnered with wine and live musical entertainment. The Fall Harvest Market offers food and floral demos, unique displays plus Kid's Patch activities. An arts and crafts show, flower market, horse-drawn carriage rides and several exceptional wine tasting and dinner events also take place around the historic downtown.
Dec 31
Holiday Lights Train
The Holiday Light Train is Pete's biggest event of the year. The park is decorated for the Holidays. See over 250,000 lights in various displays. Giant toy soldiers, candy canes, cascading snow flakes, flying reindeer, and swans swimming, just to name a few of Pete's displays!
2 - 17
Lilac Time Festival
A stunning 8.5-acre horticultural display with 800 breathtaking lilacs & 25,000 eye-catching tulips! Take tours, shop the art and craft fair, and enjoy food, drinks & sports. Enjoy the old-fashioned hospitality, free concerts and attractions that will be provided in Lilacia Park during Lilac Time!
12 - 14
City of St. Charles RiverFest
Unique among Chicagoland festivals, Riverfest features the annual ancient sport of dragon boat racing, a 40-ton Fantasy Sand Sculpture, water ski shows, carnival, petting zoo, and an assortment of events and entertainment for all ages.
CITY:St. Charles
5 - 6
Kane County Flea Market
Monthly flea market at the Kane County Fairgrounds. "The Best in the Midwest or Anywhere." Up to 1000 dealers display and sell antiques, collectibles & Fancy Junque. Food served all day.
CITY:St. Charles
23 - 28
Swedish Days Festival
This "granddaddy" of Illinois festivals features a host of family-friendly activities with live musical entertainment, a carnival, rosemaling show, pet parade, kids' day fun, grand parade, the state's largest music competition, multi-ethnic food plus great shopping in our historic downtown. Geneva's train station is located just blocks from the festivities.
Warrenville Holly Days
Holly Days, sponsored by the Warrenville Park District is the City's annual holiday celebration that marks Santa's official entry into Warrenville. Guests can enjoy a warm bonfire, raffles, free horse and carriage rides, hot cider and cookies, and, of course, a visit with Santa. Local Park District and school dance troops, singers, and bands entertain attendees during the event. It is at this event that Warrenville officially turns on its holiday lights creating an array of colors for passersby along Route 56 to see. Holly Days, primarily for Warrenville residents, gives the community an opportunity to come together and kick off the holiday season.
15 - 16
Festival of the Horse & Drum
Festival of the Horse & Drum is an equestrian festival with a diverse and exciting twist. American Indian Pow-Wow, Horsemen of Spain, Portugal & Mexico, Tanner & Glaze. Equestrian games, Equine abilities expo & more.
CITY:St. Charles
28 - 30
DeKalb Corn Fest
Corn Fest is one of the last, free, summer, music festivals among Illinois music and summer festivals in Illinois. Well over 100,000 people from around Illinois and the Midwest attend the music festival over a three day weekend. This festival features a carnival complete with rides and games, food booths, free live music, kiddie korner with large inflatables, family entertainment and much more. Friday night is carnival wristband nights for the kids with unlimited rides from 6-10pm. Festival areas feature food and business vendor booths, and a beer garden
May 1
Kane County Flea Market
"The Best in the Midwest or Anywhere" - Up to 1,000 dealers display and sell antiques, collectibles & Fancy Junque. A country breakfast is served on Sundays.
CITY:St. Charles
6 - 7
Kane County Flea Market/June 2015
Monthly flea market at the Kane County Fairgrounds. "The best in the midwest or Anywhere". Up to 1000 dealers display and sell antiques, collectibles & Fancy Junque. Food served all day,
CITY:St. Charles
25 - 26
Geneva Arts Fair
The Geneva Arts Fair transforms downtown Geneva into a venue for over 150 esteemed artists and draws a crowd of more than 20,000. The juried show was voted a Top 200 Fine Craft Fair by Art Fair SourceBook and a previous winner of "Best Craft or Art Show" by West Suburban Living magazine. Admission is free and includes a children's art area with special activities.
2 - 3
Kane County Flea Market
Monthly flea market at the Kane County Fairgrounds. "The Best in the Midwest or Anywhere". Up to 1000 dealers display and sell antiques, collectibles & Fancy Junque. Food served all day.
CITY:St. Charles
9 - 11
30th Annual St. Charles Scarecrow Festival
More than 100 handcrafted Scarecrows on display. View and vote for your favorites. Huge juried craft show, carnival, great food, continuous free live entertainment, many free children's activities, make your own scarecrow, and much more! A celebration of the autumn season!
CITY:St. Charles
23 - 24
St. Charles Fine Art Show
Located along the banks of the Fox River, this juried art show features 100 fine artists, live music, demonstrations and artists' awards.
CITY:St. Charles
5 - 6
Kane County Flea Market / December, 2015
Monthly flea market at the Kane County Fairgrounds. "The Best in the Midwest or Anywhere". Up to 1000 dealers display and sell antiques, collectibles & Fancy Junque. Food served all day.
CITY:St. Charles
25 - 27
Country Folk Art Festival
Extraordinary handmade arts and crafts made by award winning artisans. Reproductions of antique American furniture, historic crafts, folk art, primitives, unique Halloween, Christmas creations! Also some original antiques.
CITY:St. Charles
22 - 24
Red, White, & BBQ
Red, White, & BBQ is a competition dedicated to tasty barbecue, music, and fun at Ty Warner Park in Westmont. Start off the summer with great food, live music, and an all-ages carnival. Observe some of the best BBQ experts compete to win prize money, learn BBQ tips, and enjoy Ty Warner Park.
The Underpants
Play set in Dusseldorf, Germany on 1910, Louis Maske inadvertnetly drops her ill-fitting drawers in the middle of town square during a parade to honor the king.
18 - 21
This festival is attended by approximately 50,000 during the course of the weekend. PrairieFest events are held throughout Oswego with the main festival grounds located at PrairieFest Park, 91 Plank Road. The event features main stage entertainment, children's performers, expo village, petting zoos, pony rides, camel rides, children's activities, parade, bed races, touch a truck event and more. The event is free, compliments of our generous business sponsors.
Aug 27
"Concerts On The Hill"
Relax on the big grassy hill at Billie Limacher Bicentennial Park & Theatre while enjoying a variety of free family entertainment every Thursday, June 4 through August 27. Enjoy tasty, affordable concessions in a scenic setting along the waterway. Great $2 hot dogs! Picnic baskets welcome. Bring blankets and chairs for hill seating. Free parking. Visit the park's website for the performers. Every Thursday night at 6:30pm.
5 - 6
Kane County Flea Market - September 2015
"Best in the Midwest or Anywhere" monthly Flea Market with more than 1000 dealers displaying and selling antiques, collectibles & Fancy Junque. The monthly Flea Market is held the first Sunday of each month and the preceding Saturday. Food served all day.
CITY:St. Charles
3 - 4
Kane County Flea Market
Monthly flea market at the Kane County Fairgrounds with more than 1000 dealers displaying and selling antiques, collectibles and Fancy Junque. Food served all day.
CITY:St. Charles
15 - 19
Kane County Fair
Affordable family fun - carnival, entertainment, thrill events, farm animals, kids events, food, fun & more! Wed. 3pm-11pm; Thurs. noon-11pm; Fri. & Sat. noon-midnight; Sun. noon-10pm. For information visit www.kanecountyfair.com. Follow on Facebook and Twitter.
CITY:St. Charles


text:
(based on 6 reviews)
Ratings Distribution
5 Stars
4 Stars
3 Stars
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of respondents would recommend this to a friend.
Best Uses
Reviewed by 6 customers
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(2 of 2 customers found this review helpful)
Ring Sizers
By Joan
from Locust Grove, Virginia
About Me Career
Comments about Ring Size Adjuster Insert:
Although not terribly expensive it would have cost more for me to send this product back to you. I was terribly disappointed in the lack of quality and that there were no instructions included.
RIng Sizers
By Decomama
from McLean, Tx
About Me Retired professional
The product was useless to me, the metal was too soft to be springy and it won't stay on my rings. I just wasted [$] plus whatever it cost me to return them to you.
Flimsy product; no instructions
By Jeanne the Jetsetter
from New York State
About Me Classic, Comfort-Oriented, Modern
I have had this type of ring sizer before, but the metal was of a better quality. There were no instructions as to how to apply to ring. I would be afraid to trust these on my expensive rings.
(1 of 1 customers found this review helpful)
Amazing Product!
By Mrs A
from Oakland California
I bought this for my engagement ring because my fingers are very thin and I have heard too many horror stories about ring resizing. It arrived yesterday and only took my a few minutes to put on. It is comfortable and I can't feel it at all and it is barely noticeable! I am going to order the men's version for my husband's wedding band!
(6 of 6 customers found this review helpful)
By Heather
from Puyallup, WA
I purchased these ring adjusters and they are disappointing. The metal they are made from is poor quality and uncomfortable. Though different sizes, none would fit on my ring. I do not recommend this product.
(3 of 4 customers found this review helpful)
This works sort of ok
By Drag
from San Jose, CA
This works ok, but it is very hard to get on the way you want it. But once on it works


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CLOSEOUT Port Authority® 16" Tech Laptop Sleeve. BG651L
Constructed from durable neoprene with a subtle texture, this protective sleeve lets your laptop go wherever you go. A zippered opening provides quick, easy access.
For detailed PRICING, please select "Add to Cart " to view the ordering/pricing grid.


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Groovy Shell
The Groovy Shell, aka. groovysh
is a command-line application which allows easy access to evaluate Groovy expressions, define classes and run simple experiments.
- No need for
command to execute buffer. - Rich cross-platform edit-line editing, history and completion thanks to JLine.
- ANSI colors (prompt, exception traces, etc).
- Simple, yet robust, command system with online help, user alias support and more.
- User profile support
Command-line Options and Arguments
The shell supports several options to control verbosity, ANSI coloring and other features.
./bin/groovysh --help usage: groovysh [options] [...] -C, --color[=FLAG] Enable or disable use of ANSI colors -D, --define=NAME=VALUE Define a system property -T, --terminal=TYPE Specify the terminal TYPE to use -V, --version Display the version -d, --debug Enable debug output -h, --help Display this help message -q, --quiet Suppress superfluous output -v, --verbose Enable verbose output
In addition to options, commands or expressions can be given on the command-line which will invoke the shell in non-interactive mode. The commands or expressions will be evaluated and the shell will exit.
./bin/groovysh 'show preferences' No preferences are set
./bin/groovysh 'System.properties.each { k, v -> println("$k = $v") }' java.runtime.name = Java(TM) 2 Runtime Environment, Standard Edition sun.boot.library.path = /System/Library/Frameworks/JavaVM.framework/Versions/1.5.0/Libraries java.vm.version = 1.5.0_07-87 awt.nativeDoubleBuffering = true gopherProxySet = false ...
Evaluating Expressions
Simple Expressions
Evaluation Result
Multi-line Expressions
Error Handling
The shell has a number of different commands, which provide rich access to the shell's environment.
Commands all have a name and a shortcut (which is something like \h
). Commands may also have some predefined system aliases. Users may also create their own aliases.
Recognized Commands
Display the list of commands (and aliases) or the help text for specific command.
The Command List
groovy:000> help For information about Groovy, visit: http://groovy.codehaus.org Available commands: help (\h ) Display this help message ? (\? ) Alias to: help exit (\x ) Exit the shell quit (\q ) Alias to: exit import (\i ) Import a class into the namespace display (\d ) Display the current buffer clear (\c ) Clear the buffer show (\S ) Show variables, classes or imports inspect (\n ) Inspect a variable or the last result with the GUI object browser purge (\p ) Purge variables, classes, imports or buffers edit (\e ) Edit the current buffer load (\l ) Load a file or URL into the buffer . (\. ) Alias to: load save (\s ) Save the current buffer to a file history (\H ) Display, manage and recall edit-line history alias (\a ) Create an alias set (\= ) Set (or list) preferences For help on a specific command type: help <command>
Help for a Command
While in the interactive shell, you can ask for help for any command to get more details about its syntax or function. Here is an example of what happens when you ask for help for the help
groovy:000> help help usage: help [<command>] Display the list of commands or the help text for <command>.
Some of aspects of groovysh
behaviors can be customized by setting preferences. Preferences are set using the set
command or the \=
Recognized Preferences
Set the shell's verbosity level. Expected to be one of:
Default is INFO
If this preference is set to an invalid value, then the previous setting will be used, or if there is none, then the preference is removed and the default is used.
Show the last result after an execution.
Default is true
Sanitize (trim-down/filter) stack traces.
Default is true
Setting a Preference
set verbosity DEBUG
Listing Preferences
To list the current set preferences (and their values):
show preferences
Clearing Preferences (ie. Resetting to Defaults)
purge preferences
User Profile Scripts and State
Profile Scripts
Screen Shots
These shots have been taken over the development of the new shell, so some of the content might look slightly different. Also, note the yellow colors here are the shell's bold color, so the colors might look different depending on how the enclosing shell has its colors setup.


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Great Lakes Brewing Company is a principle-centered, environmentally respectful and socially conscious company committed to crafting fresh, flavorful, high-quality beer and food for the enjoyment of our customers.
We promote the responsible enjoyment of our products; if you are of legal drinking age (21 years or older), we invite you to visit our website.
Please verify your age below:
GLBC Gift Shop
2516 Market Ave
Phone: 216-771-4404
Event Website:
Public Brewery Tours
Free Brewery tours are available on the hour on Fridays from 5:00 PM – 8:00 PM and Saturdays from 1:00 PM – 8:00 PM. Please note: Brewery tours involve multiple stairwells, some of which are steep and narrow; please plan accordingly and always use caution while touring the brewing facility. We highly recommend that tour participants wear closed-toe shoes. Tour registrations do not serve as dinner reservations; please see the host for dining arrangements.
Registered guests should meet in our Gift Shop (adjacent to the Brewpub) at least 10 minutes prior to the tour start time to receive their registration tickets. Please plan accordingly around your dining plans-- tours start sharply on the hour and will not be delayed for late guests. Guests who miss their registered tour time are not guaranteed slots in earlier or later tours. Please be courteous and honor your registration! Limited walk-in slots are available for last minute tour guests. Please note: The availability of free tours on Fridays and Saturdays is subject to change due to special bookings.