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Juvenile Huntington disease
Other Names for this Disease
- Huntington disease, juvenile onset
- Juvenile onset HD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.
Huntington disease that begins in childhood or adolescence. It is also a progressive disorder that causes the breakdown of brain cells in certain areas of the brain. This results in uncontrolled movements, loss of intellectual abilities, and emotional disturbances. Juvenile HD is defined by the onset of symptoms before age 20 years and accounts for 5-10% of HD cases. It is inherited in an autosomal dominant pattern and is caused by a large number of CAG trinucleotide repeats in the HTT gene. A larger number of repeats is usually associated with an earlier onset of signs and symptoms. Most often, children with juvenile HD inherit the expanded CAG trinucleotide repeat from their fathers, although on occasion they inherit it from their mothers.[1][2]
Juvenile Huntington disease (HD) is a less common, early-onset form of
Last updated: 6/27/2011
- Warby SC, Graham RK &Hayden MR. Huntington Disease. GeneReviews. April 2010; http://www.ncbi.nlm.nih.gov/books/NBK1305/. Accessed 2/4/2014.
- Huntington disease . Genetics Home Reference. OCtober 2008; http://ghr.nlm.nih.gov/condition/huntington-disease . Accessed 6/27/2011.
Your Questions Answered
by the Genetic and Rare Diseases Information Center1 question(s) from the public on Juvenile Huntington disease have been answered. See questions and answers . You can also submit a new question.
On this page
Basic Information
- Genetics Home Reference (GHR) contains information on Juvenile Huntington disease. This website is maintained by the National Library of Medicine.
- The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
In Depth Information
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Juvenile Huntington disease. Click on the link to view a sample search on this topic.
Insurance Issues
- The Social Security Administration has included this condition in their Compassionate Allowances Initiative. This initiative speeds up the processing of disability claims for applicants with certain medical conditions that cause severe disability. More information about Compassionate Allowances and applying for Social Security disability is available online.
Other Names for this Disease
- Huntington disease, juvenile onset
- Juvenile onset HD
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.


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CHARACTER Manuel Escuela | |
Appearance(s): | Grand Theft Auto IV
The Ballad of Gay Tony (mentioned) |
Full name: | Manuel Escuela |
Also known as: | Manny The Streets |
Status: | Deceased |
Gender: | Male |
Date of birth: | 1973 |
Place of birth: | South Bohan, Liberty City |
Date of death: | 2008 (Aged 35) |
Home: | Liberty City |
Nationality: | Puerto Rican-American |
Main affiliation: | Spanish Lords Mallorie Bardas Elizabeta Torres Jay Hamilton Francis McReary Niko Bellic |
Vehicle(s): | Grey Faggio (pictured in the trailer) |
Businesses: | Youth Center |
Voiced by: | Berto Colon |
- "The streets have spoken! Now leave my people alone!"
- ―Manny Escuela
Manuel "Manny" Escuela (1973-2008) was a character in Grand Theft Auto IV. He was a 35-year old Puerto Rican ex-convict who had apparently changed his ways, and wanted to clean up the streets of Bohan.
Before GTA IV
Manny Escuela was a Puerto Rican-American who grew up in South Bohan. It is implied he was a former member of the Spanish Lords and a former heroin addict, but had now changed his ways. He claimed that he owed too much to the "streets" and wanted to clean them up to settle his debt to society. However, he had also hired a cameraman, Jay Hamilton, to film his quest, leading many to believe that he was only interested in becoming famous. He operated out of the St. Mary's Recreational Center where he ran a youth outreach program and also was a dance instructor.
Events of GTA IV
Manny was eventually introduced to Niko Bellic by his childhood friend Mallorie Bardas. Rather than personally clean up Bohan himself, Escuela paid Niko, who was broke, to do the dirty work for him in the missions Escuela of the Streets & Street Sweeper. Niko drives around town exterminating drug dealers under the request Escuela, who arrived afterwards with a camera crew to take credit. In an attempt to make his show more believable, he meets corrupt cop Francis McReary. Francis even appears in one of Escuela's videos. Later, Niko, in the mission The Puerto Rican Connection, Niko kills some of Manny's buddies.
Escuela was well-known in South Bohan, but generally disliked by most characters Niko interacts with. Even Niko is beyond irritated by Escuela's antics and ridiculous claims. At one point Escuela even took credit for the creation of rap, despite his obvious lack of skill, and implies he refused to continue because of his distaste with commercialization.
Escuela's annoying habit of filming finally went too far when he attempted to film a confrontation with another "community leader" of sorts, drug empress Elizabeta Torres. Niko goes to visit Elizabeta, but Manny and Jay arrive to tell her to stop selling drugs. However, with the police closing in on her operations, she is in a paranoid, cocaine-fueled rage and shoots both Manny and Jay in the head. She then pays Niko to deliver the bodies to a black market organ dealer, the dealer states the organs will help a lot of people, Niko says "He'd been trying to help the streets his whole life... maybe he'll be actually doing it now."
Manny Escuela was a vigilante, one who solely tried to stop neighborhood crimes, particularly gangs and drug dealers. Escuela cared more about fame and notification rather than his cause. Escuela also had a distaste of law enforcement, as in a cutscene during Street Sweeper, he was filming himself with Francis McReary, and said to his face, "you know, for a cop, you're not that bad..." As soon as McReary left, he told his viewers to distrust law enforcement and to only trust him.
LCPD Database record
Surname: Escuela
First name: Manny
Age: 35
Place of birth: South Bohan
Affiliations: Linked to the Spanish Lords
Criminal record:
- 1994 - Fraud
- 1997 - Possession Controlled Substance: Heroin
- South Bohan based fraudster and drug dealer.
- Former member of the Spanish Lords
- Reinvented himself as a community leader and started a youth center.
- Suspected in assaults against criminals around his neighborhood.
Mission appearances
- Escuela of the Streets (Boss)
- Street Sweeper (Boss)
- The Puerto Rican Connection (Boss)
- Have A Heart (Killed)
- Manny is likely based on Latin Kings leader Antonio "King Tone" Fernandez who, despite being the leader of one of New York's biggest criminal gangs, masqueraded as a community leader. Like Manny he was also the subject of a documentary entitled "Latin Kings: A Street Gang Story." Manny even wears black and gold, LK colors.
- His last name, Escuela, means "school" in Spanish.
- A mural depicting Manny can be seen in Bohan in Grand Theft Auto: Chinatown Wars, a block away from the South Bohan safehouse.
- Players are led to believe Manny used to do drugs and was a criminal. He claims he "ain't touched a drug in years" in the mission Escuela of the Streets, as well as his LCPD record noting his possession of heroin in the past.
- In The Ballad of Gay Tony, Manny's inexplicable disappearance is referenced by Troy (the doorman of Hercules), as he muses to Luis Lopez during Not So Fast "They're going to make a show about me! Can you believe it! Well, originally, they were going to make a show about some Puerto Rican guy in Bohan (Manny), but he disappeared.".
- Even though Manny seems to be somewhat homophobic, his clothing appears flamboyant as his tracksuit bears close similarity with Gay Tony's, albeit with a hood and striped ankle socks.
- Like most characters in the game, Manny will don a unique helmet when riding alongside the protagonist on a motorbike. His helmet is one of black with orange, and yellow stripes that match his outfit.
- Manny mentions during one mission that he aspires to be "like one of them rich guys who makes computers and cures AIDS and shit", a tongue-in-cheek nod to Bill Gates and his charity through the Bill & Melinda Gates Foundation.
- One of the many charity events he runs is a "Tex-Mex" cooking class, as seen in the opening cutscene for Street Sweeper.
- Manny is the only former employer not to be killed by Niko Bellic, but killed by Elizabeta Torres.
- Like Vlad Glebov, his police record status is "Missing."
- Manny likes all rap and hip-hop stations in the car. He will compliment Niko on his "beat" and will start thinking about ideas for his videos. Other stations will lead to a small but harmless argument.
- Manny's last name is misspelled in the Liberty City Post and Liberty Tree.
- He has the same last name as Javier Escuela from Red Dead Redemption, another Rockstar game. Javier is a Mexican outlaw who betrayed the game's protagonist, John Marston.
- In the beta version the main color of his jacket was blue instead of black.
- His file on the LCPD Database will list him as missing after the events of Have a Heart.
- When you fail the mission in Have A Heart, he will be listed as missing on the police computer, even though he will appear again in the mission.


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Field Education
Supervised field work provides opportunities for students to develop social work skills by applying social work concepts learned in the classroom to real-life practice situations in a variety of social work settings.
The Council on Social Work Education endorses "the role of Field Education as the 'signature pedagogy' in social work education by promoting, collaborating, recommending and distributing information to social work field educators and related membership organizations."
Working in partnership with field instructors, task instructors and agencies, the School of Social Work's field education program emphasizes preparation for practice with diverse populations and on behalf of the most vulnerable and disadvantaged groups in our society.
The Office of Field Education faculty and staff work closely with students and agencies to create high quality learning experiences that enhance maximum professional growth. The BSSW, MSW and ABA programs have specific learning outcomes that correspond to each program and concentration goals. The BSSW practicum is a two-semester experience at one agency, while the MSW and ABA practica are a mixture of one and two-semester experiences.
Field education can be a very demanding aspect of the curriculum because the student is challenged to apply the professional self to the setting and to integrate learning into practice. The Office of Field Education is eager to make field work a memorable and significant experience in the development of each student as a social work professional.
For more information about field education contact:
Karen Bolinger
Administrative Secretary of Field Education


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I would've had Joubert slightly higher too. At least higher than Chan.
I would've had Joubert slightly higher too. At least higher than Chan.
No, and I don't think many casual fans would either. Most viewers cannot tell the difference between between a flip or a lutz or even a salchow and a loop. It's not as obvious as the different dives and I don't think regular people would enjoy watching jump to jump to jump. Plus, sorry but watch someone jump a foot off the ice over and over again is not as exciting as watching someone plunge off the highest diving board.....
Still .... about Joubert, I'm kind of torn and I haven't even gotten to watch Chan, who is above him. Dai was perfect and I'm in total awe of his footwork. It's so gorgeous and seemless, you totally forget he is trying to get points. But Joubert was really on fire and he did do that huge combination...
Besides, even though I like watching other skaters more, part me hopes Joubert wins the whole thing just to show his stupid federation. what would they say then?
Last edited by Layfan; 03-24-2010 at 07:59 PM.
I thought Patrick did more than Dai today. His skating was like a CoP clinic and I was surprised he didn't score a bit more.
As Patrick noted, Dai sold it better. I could say Joubert sold it better too - but I am just not buying what Joubert is selling.
If I want to see that type of action I prefer watching the original - John Travolta in "Saturday Night Fever."
What happened to Oda? I feel really bad for him even though I am not a big fan. Maybe his ancestor, warrior Oda put a curse on him. He may not like the fact that Nobunari is a skater not a conquerer of Japan.Maybe he wanted him to become a prime minister instead of a figure skater.
Takahashi and Joubert really SOLD their programs. Chan was excellent technically, but it's a bit like watching a windup toy going through its paces---no audience connection. Yes, Chan earns high TR and CH scores, but PE and IN scores should be considerably lower than Dai and Brian's.
I also think Abbott was robbed. He should have scored in the 84-85 range, certainly higher than Brezina.
Cant stand Chan. He needs to compete with MAO.
True! Because Abbott was in the earlier group. The earlier group skaters don't usually get the same or higher PCS corridor. That's why, and That's why it's stupid.
I don't get it. If Rippon and Brezina could get those high scores, then Abbott was definitely underscored. I thought that Abbott should be in the 84 range.
As of Joubert, with his performance and technics for today, I have no doubt that he should be in the first place. At least should be in front of Chan. To see the performances today, I believe that raising the quad's value is absolutely necessary and a valid argument.
Last edited by jennylovskt; 03-24-2010 at 10:10 PM.
Do people really think Abbott is that much better than Rippon or Brezina? I mean maybe at his best he's a bit better, but I watched him today, he looked super nervous and didn't really sell the program. I'd say this is comparable to what happened to Mirai in the SP at the Olympics, Miki and Rachael were ahead of her and some people thought that was outrageous, but essentially it was a 3 way tie, and Mirai skated early, and she was a bit tentative and her combo wasn't the best. The same holds true with Jeremy, his scores are the way they are because: 1.) He skated early 2.) He skated tentatively 3.) The landing on his 3a wasn't great. Also, he, Brezina, and Rippon are essentially tied, and he's maybe paying his dues for being a headcase (he was only 11th at worlds last year and not so great at the Olympics a few weeks ago).
Do you think it's fair to argue that he supposedly should get a lower score because he skated earlier? I know it was the fact but it was not fair! Rippon had a rugh, even worse landing in his 3A. Brezina skated nervously too. If you compare Jeremy's skating today with his Nationals SP, this time wasn't as good as that time. But his score definitely shouldn't be this low if everyone's scores are that high.
Adam deserved the score he got- he had stepped out of 3A and based on how other top skaters performed today he simply could not afford a mistake. But I do agree that joubert should have been placed before chan- not a fan of his skating but he sold his program in a unique way and it was pretty uplifting.
I don't think it's fair that he got lower scores because he skated earlier, I'm just saying that it probably played a factor in his slightly low score. Fair or not, it's just the reality, for example, I kind of doubt Mirai would have finished 4th at the Olympics if she had skated when Rachael skated instead of skating last - that does not mean she didn't deserve to win 4th, I thought she deserved to win 3rd, but it's unfortunately one of the drawbacks of this sport. Jeremy skates first in the last group tomorrow too, so he may be at a slight disadvantage but considering his nerves I actually think it's a good thing he skated early in both the SP and the FS, and for him, I think skating two clean programs at an event like Worlds is more important than if he places 4th or 6th, in this deep field of men, medaling is a stretch for him anyways. He looked satisfied with his scores in the Kiss and Cry, and most importantly I think he gained his confidence back.
All well, at least Abbott shouldn't be robbed that much in LP because he will be in the last group to skate. The system is as funny as this!


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HEAT oven to 350°F.
PREPARE cake batter as directed on package; tint with food coloring. Pour evenly into 2 greased and floured 9-inch round pans.
BAKE as directed on package. Cool in pans 10 min.; remove to wire racks. Cool completely.
BEAT cream cheese and powdered sugar with mixer until well blended. Stir in COOL WHIP with whisk. Spread onto tops and sides of cakes.
CUT each cake into 8 wedges to resemble Christmas trees. Insert peppermint stick into curved side of each cake for the tree trunk. Decorate with remaining ingredients.


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In-Depth Impact
The centers forge partnerships in Asia as well as locally in Southern California to share ideas and sponsor further research.
Center for Biotechnology and Global Health Policy
The center serves as a reference point for research, policy development and advocacy concerning science, biotechnology, bioethics and healthcare in the U.S. and abroad.
Center on Globalization, Law and Society
The Center on Globalization, Law and Society is the umbrella center for the study of international, transnational and comparative law at the University of California, Irvine School of Law.
Center for Land, Environment, and Natural Resources
The center seeks to make UCI Law a nationally recognized site for scholarship, education, community outreach and public engagement on environmental, natural resources and land use law.
Center on Law, Equality and Race
The center was created with the goal of promoting greater racial equality through research, education, and advocacy.
Center in Law, Society and Culture
The center brings together UCI faculty and graduate students who share interests in law, society, and culture, and sponsors collaborative research projects. UCI Law Prof. Catherine Fisk is co-director.
UCI Interdisciplinary Center on Family Violence
This center unites community partners with faculty from 20 UC Irvine departments to be the premier site for research, education, clinical care, and community collaboration on family violence prevention and intervention.
Korea Law Center
The mission of the Korea Law Center is to promote practical solutions to problems arising at the intersection of U.S. and Korean law.
The U.S.-China Institute
The John S. and Marilyn Long U.S.-China Institute for Business and Law is designed to be a premier research entity that will forge ties between the U.S. and China.


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John (AKA knife141) loves turning junk into unusual creations, and one day came up with idea of building a camera for the sole purpose of confusing strangers. He took a $15 digicam and transformed it into a Argus C3 from the mid-1900s:
My goal was to install a modern digital camera inside the housing of an old, obsolete camera. I thought it might be fun to pull this camera out in a crowd of people and make them wonder why in the world an old man would continue to use a camera that was obviously as old as he was, as opposed to something more modern.
[…] I've had a lot of fun with this camera, taking it places and watching people's puzzled looks as I appear to be using an old beat-up camera that was made about the time I was born! I have even had people approach me and ask if I can still get film developed — with no idea that the heart of my camera is actually digital! I have also had people ask me how many pictures I can take with the camera, and they always look puzzled when I tell them, "Oh, around 4,000 or so."


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Patent commissioner, media industry leader chosen for SUNY honor
The State University of New York trustees have approved awarding honorary doctoral degrees to two outstanding members of SUNY Oswego's class of 1977: a media industry leader and the U.S. commissioner of patents.
Fri Oct 03, 2014
Media summit founder to receive SUNY Oswego's Presidential Medal
Media industry leader, cable television pioneer and SUNY Oswego alumnus Louis A. Borrelli Jr. will receive the college's Presidential Medal on Thursday, Oct. 16, the day of the media summit he founded a decade ago.
Fri May 02, 2014
Talent manager to help wrangle alumni, seniors on Commencement Eve
Constance Schwartz, a 1990 graduate of SUNY Oswego with a successful career in marketing and talent management, will serve as mistress of ceremonies for Commencement Eve activities at the college Friday, May 16, including the dinner and traditional Torchlight Ceremony.
Thu Mar 27, 2014
College convocation speaker: 'Live Your Passion'
Living her passion every day fuels Tracy Chamberlain Higginbotham, a 1986 SUNY Oswego graduate who will be the featured speaker at the college's Honors Convocation. The ceremony will begin at 3 p.m. April 11 in the Campus Center's arena and convocation hall.
Mon Mar 24, 2014
PwC chairman to speak in Oswego about global trends
Bob Moritz, chairman and senior partner of the U.S. accounting firm PricewaterhouseCoopers and a 1985 graduate of SUNY Oswego, will discuss "Global Trends and Your Role in a Sustainable Future" at 7 p.m. Thursday, April 3, in the auditorium of the college's Campus Center, Room 132.
Wed Mar 12, 2014
Noteworthy alumni Bocko, Baum, Clement to speak at Oswego Commencement
Accomplished SUNY Oswego alumni Peter Bocko, Mark Baum and Linda Clement each will address a Commencement audience as SUNY Oswego moves to three May graduation ceremonies for the first time.
Mon Nov 04, 2013
SUNY Oswego inducts four into Athletic Hall of Fame
Four former standout athletes at SUNY Oswego recently joined the ranks of 78 other accomplished individuals who have been voted into the college's Athletic Hall of Fame, forever solidifying themselves in the college's athletic history