text:
The Community of Disc Golfers and About All Things Disc Golf
Ceej has not received any gifts yet
Hey Chris !!! I just Tried to add you as a Friend here , but I get this message :
You have reached the maximum limit of 100 outstanding friend requests across your Ning Networks.
If I could ask you to sent me a request , I can add you that way. That would be Cool !!!
Thanks ,
Donny Olow
Hello Chris ( Ceej ) !
Greetings !!
Wishing you Lots of Birdies and Hole-In-Ones !!!
Hope this message finds you well and your enjoying the 2011 Season !!!
Welcome to this Cool Website for Disc Golfers from All over the World !!!!
Enjoy !!!!!
Your Friend from the SouthWest !!!!
Donny Olow
San Diego , CA .
Welcome to
Posted by Alan Barker on October 30, 2014 at 12:40pm — 1 Comment
Posted by Alan Barker on January 29, 2014 at 2:26pm
Posted by Alan Barker on November 4, 2013 at 1:38pm
Posted by Frederick Cranford on September 11, 2013 at 5:42am
Posted by CoolDaddySlickBreeze on August 13, 2013 at 4:40pm
© 2015 Created by Terry "the Pirate" Calhoun.


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Call of the Wildman Ernie's Faux Leather Jacket
Product Rating
Sale Price:
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You Save: $59.98 60% off
- Additional Details
- Color: Brown
- Fit: Standard Fit
- Made In: U.S.A.
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When hes not shirtless the Turtleman can be found in his unique leather Jacket. With brown and black leather, fringe, pockets, and metal details its clear that not only his personality makes him stand out. You can look just like Ernie in the Call of the Wildman Ernies Faux Leather Jacket. The faux leather piece lets you be just like Ernie. So pull on this jacket and let out your own Turtleman call of Yi Yi Yi!

subset: commoncrawl


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M&A has turgid start in '13, but what's next depends on sellers
Blog Entry:
February 20, 2013 4:30 AM | Author: JIM HILL
Jim Hill is the executive chairman of
, chair of the firm's private equity group and an active and practicing member of its corporate and securities practice group. He focuses his active practice on publicly and privately held growth companies in addition to representing mezzanine finance providers and equity participants.
The fourth quarter of 2012 brought a sigh of relief to investment bankers, senior and mezzanine lenders and strategic and financial buyers as the pace of deals quickened, due in large part to looming capital gains tax changes coming in the dawn of 2013.
But that relief quickly turned to deep concerns in the deal community because the deal pipeline for both strategic and financial buyers became nearly empty with few great prospects in sight for the first quarter of 2013.The question that must be asked is: Why is this the case, with leverage being so abundant for leveraged buyouts, interest rates being so low and with so little inventory? Wouldn't this be a great time to be a seller given the law of supply and demand?To be sure, the capital overhang in the U.S. private equity world alone that will burn out, if not committed to investments in the next two years, is about $280 billion. What that means is you, as a principal of a private equity firm, have capital commitments from your limited partners that are usually of a five-year term. If that money isn't invested, then it goes back to the limited partners, and you cannot earn your 2% asset management fee on those dollars. So, the incentive is in place to invest.
Also, U.S. corporate entities that are not owned by private equity have balance sheets of more than $2 trillion of cash that is available in most instances for acquisitions. Given the continued slow pace of organic growth in almost every industry, value creation must be driven by acquisition.
So, why so few sellers, and will that change? Answers to the first question include:
1. Sellers' continued concerns about the sustainability of their earnings for their companies, thus possibly achieving a lower purchase price in a sale process.
2. Private sellers, who are not sponsored, feeling that even if their internal company return on equity is single digits today, it is still a better return than what they can do with the proceeds of a sale after paying their transactions costs and taxes.
3. Potential sellers looking over the remains of the 2012 landscape of auction sales, where, in many instances, "busted auctions" occurred due to companies either not hitting their earnings forecasts or actual pricing not being as high as the seller would expect.
What may and can change this current state of semi-paralysis would be a) strategic buyers deciding that acquisition growth is a key way to create shareholder value today as organic growth remains challenging, b) private equity firms having to spend the capital commitments they have been given and c) perhaps sellers realizing that their 2013 earnings are better than 2012 (not on a "hockey stick" uptick) and positive enough to sell a business that has either or both succession challenges and industry consolidation challenges as the "big get bigger" in their markets.
Why should the general public care if the 2013 uptick does or does not happen? Well, many companies are cash constrained due to their inability to borrow more senior debt to grow despite their working capital needs. Further, many other companies are capital constrained from making the physical improvements to their operations that must be made to remain competitive within their industry and the world markets. If they do not sell or recapitalize their business, these events (which also create jobs) will not occur.
So, for transactional folk, harder work is demanded in 2013 that will be beneficial to all.
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Lyles returns from hand injury to battle Cubs
Arrieta takes hill for Chicago as series continues
It's already August, but as far as Jordan Lyles is concerned it might as well be early April. The right-hander, who has not pitched since suffering a fractured left (non-throwing) hand June 4 on a play at the plate, will make his return to the mound Wednesday night at Coors Field against fellow righty Jake Arrieta and the Cubs.
And he's pretty excited about it.
"I'm just ready," said Lyles, who will end a run of 20 consecutive starts by lefties for the Rockies. "I've been sitting around watching, watching and it's finally here. I'm just ready to get after it. My excitement level is up there with an Opening Day start."
Lyles' return comes after a rocky two months on the disabled list. He had been scheduled to pitch July 28, but X-rays revealed his hand had not healed as expected and Colorado moved him to the 60-day DL. That made him ineligible to return until Monday.
Lyles is expected to throw 85-100 pitches after tossing a pair of scoreless rehab outings, in which he lasted a combined 8 1/3 innings while scattering six hits and four walks and striking out eight. Lyles worked up to 66 pitches with Triple-A Colorado Springs on July 30.
Manager Walt Weiss is prepared for a less-than-perfect Lyles, who pitched to a 3.52 ERA and 1.30 WHIP in 12 starts before getting hurt.
"I think when you miss as much time that Jordan has, you're not going to have impeccable command your first time back," Weiss said. "I don't think there'll be any difference in his velocity. Because of the nature of his injury, he's been able to throw even when he's been away."
Arrieta knows about going deep into games. He has pitched at least six innings in each of his last 10 starts, and has lasted at least seven frames in six of them.
Most recently was a one-run, seven-inning effort against the Rockies on Thursday. Colorado's top five hitters went a combined 4-for-19.
"His confidence, his composure -- the ability to use, in practical terms, his stuff. He's got great stuff," manager Rick Renteria said of Arrieta's breakout campaign. "There are situations this year where he might have gotten into a little traffic and was able to manage that traffic well, where in the past, he might have gotten into that traffic and had it snowball. Every outing, his confidence has gotten better and better."
This will be the first time in Arrieta's five Major League seasons that he will face the same team in consecutive starts.
Cubs: Kyuji Fujikawa rejoins club, could be activated Wednesday
Right-hander Kyuji Fujikawa, a 34-year-old who signed with the Cubs out of Japan in December 2012, rejoined the club in Denver and is expected to be activated from the DL this week, potentially Wednesday.
Fujikawa hasn't pitched for the Cubs since May 2013. He underwent Tommy John surgery a month later.
"He came in [Tuesday] and said he's ready to go, however I want to use him," Renteria said. "We'll try to find a spot that suits him the best."
In 11 2/3 innings spanning 12 Minor League rehab appearances, Fujikawa allowed two runs (one earned) on seven hits and three walks. He also struck out 13 batters.
Rockies: CarGo 'probably' back in lineup Wednesday
Weiss feared worse when Carlos Gonzalez hurt his right ankle Friday, but as it turns out, all the Rockies outfielder needed was a couple of days to rest. Gonzalez will "probably" be back in the lineup and starting in right field on Wednesday, according to Weiss.
"I'm feeling good," Gonzalez said before the game. "Hopefully I get the start [Wednesday]."
Added Weiss: "He's [someone] who I thought was going to be a possible DL situation. But he's made a lot of improvement and I want to give him a day to do some baseball activity."
Gonzalez, who walked in his pinch-hit appearance Tuesday, has hit .170 (9-for-53) with 21 strikeouts and three walks since returning from finger surgery on July 11. In 66 games this season, Gonzalez has a career-low average (.237) with 10 homers and 36 RBIs.
Worth noting:
• Rockies left-hander Brett Anderson left his start Tuesday in the fourth inning with lower back spasms.
• Javier Baez was 0-for-5 with three strikeouts in his Major League debut Tuesday before his 12th-inning homer put the Cubs on top. Baez, 21, is the Cubs' No. 2 prospect.
Tim Healey is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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ACL2 accepts 256 distinct characters, which are the characters
obtained by applying the function code-char
to each
integer from 0 to 255. Among these, Common Lisp designates certain
ones as *standard-characters*
, namely those of the form
(code-char n)
where n is from 33 to 126, together with
and #\Space
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be viewed by evaluating the constant expression
The standard character constants are written by writing a hash mark followed by a backslash (#\) followed by the character.
The function characterp
recognizes characters. For more
details, See characters .


text:
Daily OCD Extra: November's Book Reviews | |
Written by Jen Vaughn | Filed under reviews, Kim Deitch, Jim Woodring | 28 Oct 2013 4:10 PM |
Next month's issue of Booklist will include reviews of two recent releases by Fantagraphics creators, excerpted below:
The Amazing, Enlightening and Absolutely True Adventures of Katherine Whaley by Deitch, Kim (Starred Review)
"The yarn Deitch spins around that outrageous premise includes surprisingly less of the supernatural and many more words than usual, which wrap around the panels and are carefully chosen to project the heroine's personality-that of a smart but unpretentious woman who once had an utterly fantastic adventure. Even more riveting than Deitch's other spellbinders." –Ray Olson
Fran by Jim Woodring
"the heightened emotional stakes are new: Frank's followers have watched him shrug off violent treatment with the resilience of a Warner Bros. cartoon character, but the loss of Fran seems more devastating than the worst punishment he's received at the hands of the devilish Whim."
–Gordon Flagg


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Nashville's New Country on Hot Country Z 101.7
General This category includes all events not assigned a specific caegory |
Start : Sunday 10th of March 2013 07:00:00 PM End : Sunday 10th of March 2013 08:00:00 PM |
Contact info : |
Email : URL : |
Posted by Tom on Tuesday 12th of March 2013 10:36:52 AM
It's the newest weekend program on Hot Country Z 101.7, bringing you up-and-coming songs in the world of country music! Tune in twice every weekend, Saturday mornings from 10 to 11 o'clock and Sunday evenings from 6 to 7 o'clock for "Nashville's New Country", hosted by Steve Southard! |
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Presenting a magnificent silk and wool blended woven made especially for Mood. This gorgeous, medium-weight fabric has a satiny sheen on one side, contains a slightly thicker hand, and consists of a soft drape. This elegant fabric is perfect for special occasion wear including luminescent suits, striking pants, stunning jackets, and gorgeous dresses. Available in 48 attractive shades.
Color: Winter Sky
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Content: 51% SILK, 49% WOOL
Learn about fabric careHOW TO CARE FOR SILK:Dry cleaning is usually preferable, but silks can be hand-washed or machine-washed on delicate, cool water. Line dry. Test a swatch first.Mood strongly recommends test-laundering a swatch, if you plan to wash your garment or home furnishings yourself. -
PLEASE NOTE: The above numbers are estimations only. Please take into account garment size, lining and fabric width.


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[Skip to content]
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Every child deserves the best possible start in life and the support that enables them to fulfil their potential.
If you are a childcare practitioner in the target group, you'll find the latest information on early years and childcare courses below.
Our aim is to continue to support you to make a difference for children, young people and their families, improve outcomes for children and to develop diverse, high quality childcare provisions across our county with relevant and appropriate training.
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An alternative way to undertake training or CPD
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I think there are not that many artists out there who are able to make nice 3d models.
What we did with MegaGlest is to make modding the game VERY easy. even kids can do this and by this we go more and more people who mainly make artwork and many mods! The big benefit that even other OpenSource projects will have from this, is the fact that there are many people now, learning how to use blender/gimp to make 3d models! So give the people really easy ways to modify things and you will see many more artists soon, who simply have fun to create good artwork for open source games .
examples what modders do! ( That they cannot do more is mainly a problem of the older engine :-( ) :


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Butcher Block Top Kitchen Island in White Finish with 24" Black School House Stools
Be the first to review this product!Catalog Item # 64222
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Behind the doors, you will find adjustable shelves and an abundance of storage space for objects you'd prefer to keep hidden. Deep push-through drawers are great for holding essential items, such as utensils or storage containers. Style, function, and quality make this kitchen island a wise addition to your home.
Technical Specs
Weight: 186.4 lbs.
Open Dimensions 23in deep X 48.25in wide X 36in high
Folded Dimensions 23in deep X 48.25in wide X 36in high
Manufacturer: Modern Marketing Concepts
Mfg Part #: KF300062W
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Syracuse Fit2Win Lacrosse Shorts
The Syracuse Orange have been one of the most dominate teams since the start of the lacrosse program in 1916. Syracuse has won the most NCAA Championships with 11 and still holds the record for consecutive appearances in the NCAA Final Four. The Gait brothers, Paul and Gary, and the Powell brothers, Casey, Ryan and Mikey, have been just a few of the legends to wear the Orange for Syracuse.
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Home > Health Library > Hospital Discharge Planning
Discharge planning helps to make sure that you leave the hospital safely and smoothly and get the right care after that.
You, the person who is caring for you, and your discharge planner work together to address your concerns in a discharge plan. Whether you go home, to a relative's home, to a rehabilitation facility, or to another health care setting, your plan outlines the care you need.
A day or two before you expect to leave the hospital, ask to meet with your discharge planner.
Your discharge planner can tell you why you are going home or to another health care setting and why your care is changing. You will work together on:
Write down any questions you have about what will happen when you get home, what your family can do to help, or who's going to pay for your care.
To help you plan what you'll need after leaving the hospital, use this hospital discharge checklist(What is a PDF document?).
Why would your doctor say you're ready to go home when you may not feel ready?
Talk to your doctor about your worries. Even though you don't feel strong enough to go home, your doctor can explain why it's important for you to go home or go to another health care setting.
If you're really not comfortable with your doctor's recommendation that you go home, ask for help from the hospital's patient advocate.
If you have been living in another health care setting—for example, a nursing home or a rehabilitation hospital—you'll have to talk with someone about leaving for your hospital stay and then coming back afterward. Find out what you'll have to do to get the same bed and room, and ask about any costs.
If you have been living at home but will need to go to another setting when you leave the hospital, the discharge planner can give you a list of options. You, a family member, or a friend will have to call around to see which one you prefer. Things to think about when choosing another setting include:
Before you leave the hospital, talk to your nurse or other hospital staff about things you'll have to do at home. Get information in writing about:
It's easy to think you can do everything, but it can be hard. If you feel you or your caregiver won't or can't do certain tasks, say so. Try to make other arrangements.
After you leave the hospital, the best way to benefit from your treatment is to take good care of yourself. Remember that you are the most important member of your health care team.
Follow your doctor's instructions, which may include things like taking medicines as prescribed, getting needed exercise, or knowing how to take care of an incision from surgery.
Taking good care of yourself after you get back home is the best way to avoid a return trip to the hospital.
Other Works Consulted Agency for Healthcare Research and Quality (2011). 20 Tips to Help Prevent Medical Errors. Patient Fact Sheet (AHRQ Publication No. 11-0089). Rockville, MD: Agency for Healthcare Research and Quality. Also available online: http://www.ahrq.gov/consumer/20tips.pdf. Anspaugh DJ, et al. (2011). Becoming a responsible health care consumer. In Wellness: Concepts and Applications, 8th ed., pp. 453–484. New York: McGraw-Hill. Hyman D (2012). Advancing the quality and safety of care. In WW Hay Jr et al., eds., Current Diagnosis and Treatment: Pediatrics, 21st ed., pp. 1–8. New York: McGraw-Hill. Shepperd S, et al. (2010). Discharge planning from hospital to home. Cochrane Database of Systematic Reviews (1). Wachter RM (2012). Quality of care and patient safety. In L Goldman, A Shafer, eds. Goldman's Cecil Medicine, 24th ed., pp. 41–44. Philadelphia: Saunders.
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Wellness Center
The Helen Hayes Hospital Wellness Center is a professionally supervised exercise facility dedicated to promoting lifelong fitness. The Center offers an ideal, fully accessible setting for a structured wellness program. Applications are accepted from individuals who have any type of medical diagnosis, including but not limited to
- cardiac disorders
- pulmonary disorders
- orthopedic disorders
- osteoporosis
- arthritis
- stroke
- spinal cord injury
- brain injury
- multiple sclerosis
The goal is for community participants to continue building endurance, strength and flexibility and maintain an active and healthy lifestyle. Although many participants have previously received therapy at the hospital, the program does not require that participants have had any type of therapy or treatment at Helen Hayes Hospital.
Exercise programs are developed jointly by instructors and participants and are dependent on the individual's medical condition, goals and fitness level. All members receive a thorough orientation that encompasses both the mechanics of the equipment and specific usage instructions tailored to meet their particular physical needs. All exercise sessions are supervised by Certified Recreational Therapy Specialists and a personal trainer is available to consult on the development of a customized exercise program.
The Wellness Center houses a complete range of aerobic and weight training equipment for people of all abilities, including treadmills, stair steppers, stationary and recumbent cycles, ellipticals and upper body cycles. There is equipment designed specifically for wheelchair users as well as adaptive devices to assist those with limited dexterity.
For additional information on the Wellness Center, please call 845-786-4194 or 1-888-70-REHAB, ext. 4194, or click here


text:
Astros look to end homestand on high note
Cosart hopes to build on strong debut against Wilson, Angels
The opening homestand looked intimidating for a young Astros team that's trying to find its footing, with three games against the free-spending Yankees and four others against the star-laden Angels.
Win on Monday, and they will have finished it with a 4-3 record.
"That would be great," said Astros catcher Jason Castro, whose team will then venture on a six-game road trip through Toronto and Arlington. "Obviously, to come out ahead on the opening homestand would be great. It would set the tone for going on the road and that's the kind of baseball we're looking to play. We did it against the Yankees early, the first couple, and we did it again today. If we can jump out ahead and keep the pressure on all game, that's what we're looking for."
With a chance to split the four-game set against the Angels on Monday, on the heels of a 7-4 win that was sparked by five homers and a stellar Scott Feldman outing, the Astros will send 23-year-old right-hander Jarred Cosart to the mound. Cosart is coming off throwing five scoreless innings against the Yankees and will oppose Angels lefty C.J. Wilson, who was charged with six runs in 5 2/3 innings against the Mariners in his 2014 debut.
The Angels desperately need a good start this season, after sporting the fourth-worst April winning percentage in the Majors the previous two years, and winning this series is crucial.
"We're just trying to come together and play as a team," Wilson said. "That's what's important to happen. But at the end of the day, if you're not getting the job done, you're not getting the job done. And everybody's accountable for that because this is the Major Leagues. We're not in Double-A, we're not in Triple-A, we're not in Spring Training anymore. These are real games. We need to put our best foot forward and try to win every night, and when we don't do that, we don't sleep well. Nobody on the team is happy."
Angels: No specific battery pairings
Hank Conger caught 24 of Wilson's 35 starts last year, with Chris Iannetta, pretty much considered the everyday catcher, behind the plate for the other 11. But Wilson had a 3.36 ERA with Conger and a 3.46 ERA with Iannetta, and Angels manager Mike Scioscia said he isn't pairing Conger exclusively with Wilson.
"That's not a factor," said Scioscia, who started Conger on Sunday. "Either catcher is fine with me."
Astros: Houston thankful for Presley move
The Astros were going to carry 13 pitchers to enter the season, until they claimed outfielder Alex Presley off waivers just before Opening Day. And with Dexter Fowler's status still uncertain -- he's out of the hospital after battling a stomach virus, but manager Bo Porter isn't sure if he'll make the trip to Toronto -- Presley has had to step up as a quasi-everyday player.
"It was definitely something you look at now," Porter said of acquiring Presley, who's 3-for-15 with a homer thus far. "Had we not made that decision, it would have been very difficult with everything that's happened to Dexter the last few days here."
Worth noting
• The Astros have scored in the first inning in five of their six games this year, for a total of nine runs.
• Angels first baseman Albert Pujols remains one RBI away from 1,500 for his career. When he gets it, he'll join Alex Rodriguez as the only active players to reach the milestone.
Alden Gonzalez is a reporter for MLB.com. Read his blog, Gonzo and "The Show", and follow him on Twitter @Alden_Gonzalez. This story was not subject to the approval of Major League Baseball or its clubs.


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Collectivist and individualist cultures
this wiki
Assessment |
Biopsychology |
Comparative |
Cognitive |
Developmental |
Language |
Individual differences |
Personality |
Philosophy |
Social |
Methods |
Statistics |
Clinical |
Educational |
Industrial |
Professional items |
World psychology |
Social psychology: Altruism · Attribution · Attitudes · Conformity · Discrimination · Groups · Interpersonal relations · Obedience · Prejudice · Norms · Perception · Index · Outline
- For judgements of value about collectivism and individualism, see individualism and collectivism. This article regards how 'collectivist' and 'individualist' are used descriptively in anthropology and cultural psychology.
Cultures are typically divided into two categories: collectivist and individualist. Individualist cultures, such as those of the United States and Western Europe, emphasize personal achievement regardless of the expense of group goals, resulting in a strong sense of competition. Collectivist cultures, such as those of China, Korea, and Japan, emphasize family and work group goals above individual needs or desires.
Collectivism and individualism deeply pervade cultures. People simply take their culture's stance for granted. In the U.S., everything from 'self-serve' buffet tables to corporate structure to cowboy movies reflect the deeply ingrained individualism.
Both collectivist and individualistic cultures have their failings. People in individualist cultures are susceptible to loneliness, and people in collectivist cultures can have a strong fear of rejection.
[show]Traits of Collectivism
- Each person is encouraged to be an active player in society, to do what is best for society as a whole rather than themselves.
- The rights of families, communities, and the collective supersede those of the individual.
- Rules promote unity, brotherhood, and selflessness.
- Working with others and cooperating is the norm; everyone supports each other.
- as a community, family or nation more than as an individual.
Traits of Individualism
- "I" identity.
- Promotes individual goals, initiative and achievement.
- Individual rights are seen as being the most important. Rules attempt to ensure self-importance and individualism.
- Independence is valued; there is much less of a drive to help other citizens or communities than in collectivism.
- Relying or being dependent on others is frequently seen as shameful.
- People are encouraged to do things on their own; to rely on themselves
Examples of Countries with Generally Collectivistic Cultures
- Argentina
- Belarus
- Brazil
- Bulgaria
- China
- El Salvador
- Egypt
- Greece
- Hong Kong
- Italy
- India
- Japan
- Korea
- Lebanon
- Portugal
- Romania
- Russia
- Ukraine
- Serbia
- Singapore
- Taiwan
- Turkey
- Malaysia
- African countries (Zambia, Kenya, Somalia, etc)
- Israel
Examples of Countries with Generally Individualistic Cultures
- Germany
- Austria
- Switzerland
- Canada
- Australia
- United Kingdom
- France
- Ireland
- Poland
- Czech Republic
- Finland
- Estonia
- Hungary
- United States
- The Netherlands
- Belgium
- Luxembourg
Attribution is the process of understanding the actions of others based on limited information. Since the process is inexact, large errors often creep in. In individualistic cultures, there is a strong bias towards attributing a person's behavior to the characteristics of that person, instead of to the situation that person is in. This is called the fundamental attribution error. People in collectivist cultures have this bias to a much lesser degree.
Personality Types
The stereotype of a 'good person' in collectivist cultures is trustworthy, honest, generous, and sensitive, all characteristics that are helpful to people working in groups. In contrast, a 'good person' in individualist cultures is more assertive and strong, characteristics helpful for competing.
The idea of the 'artistic type' or 'bohemian' is not usually found in collectivist cultures. However, collectivist cultures usually have a 'community man' concept not present in individualist cultures.
Collectivism and individualism in Chinese culture
In Chinese society, collectivism has a long tradition based on Confucianism, where being a 'community man' ([qúntǐ de fènzǐ) (群体的分子) or someone with a 'social personality' (shèhuì de réngé) (社会的人格) is valued. Additionally, there is the [shìgu (世故) personality type, who is worldly and committed to family.
Individualist thinking in China was formed by Lao Zi and Taoism. He taught that individual happiness is the basis of a good society and saw the state, with its "laws and regulations more numerous than the hairs of an ox," as the persistent oppressor of the individual, "more to be feared than fierce tigers." He was an opponent of taxation and war, and his students and the tradition that followed him were consistently individualistic.
See also
- Asian values
- Collectivism
- Face (social custom)
- Individualism
- Masculinity vs femininity
- Nevis's hierarchy of needs
- Power distance
- Uncertainty avoidance
- Western culture
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- Liver cirrhosis (2)
- Alcoholic liver disease (1)
- Fibrotest (1)
- Genetic testing (1)
- Hepatitis (1)
- Hepatotoxicity (1)
- Interleukin-22 (1)
- Wie wirksam sind neue Therapien für Hepatitis C? : Mathematische Modellierung charakterisiert den individuellen Behandlungserfolg (2009)
- Die derzeitige Therapie der chronischen Hepatitis C ist komplex und mit zahlreichen Nebenwirkungen assoziiert. Um den Therapieerfolg frühzeitig vorhersagen zu können und die Behandlung individuell zu optimieren, greifen Forscher des Frankfurter Leberzentrums auf mathematische Modellierung zurück. ...
- Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors (2010)
- Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined. Virus cell entry involves human scavenger receptor class B type I (SR-BI), CD81, claudin-1 and occludin. Among these, at least CD81 and occludin are utilized in a highly species-specific fashion, thus contributing to the narrow host range of HCV. We adapted HCV to mouse CD81 and identified three envelope glycoprotein mutations which together enhance infection of cells with mouse or other rodent receptors approximately 100-fold. These mutations enhanced interaction with human CD81 and increased exposure of the binding site for CD81 on the surface of virus particles. These changes were accompanied by augmented susceptibility of adapted HCV to neutralization by E2-specific antibodies indicative of major conformational changes of virus-resident E1/E2-complexes. Neutralization with CD81, SR-BI- and claudin-1-specific antibodies and knock down of occludin expression by siRNAs indicate that the adapted virus remains dependent on these host factors but apparently utilizes CD81, SR-BI and occludin with increased efficiency. Importantly, adapted E1/E2 complexes mediate HCV cell entry into mouse cells in the absence of human entry factors. These results further our knowledge of HCV receptor interactions and indicate that three glycoprotein mutations are sufficient to overcome the species-specific restriction of HCV cell entry into mouse cells. Moreover, these findings should contribute to the development of an immunocompetent small animal model fully permissive to HCV.
- A multi-variant, viral dynamic model of genotype 1 HCV to assess the in vivo evolution of protease-inhibitor resistant variants (2010)
- Variants resistant to compounds specifically targeting HCV are observed in clinical trials. A multi-variant viral dynamic model was developed to quantify the evolution and in vivo fitness of variants in subjects dosed with monotherapy of an HCV protease inhibitor, telaprevir. Variant fitness was estimated using a model in which variants were selected by competition for shared limited replication space. Fitness was represented in the absence of telaprevir by different variant production rate constants and in the presence of telaprevir by additional antiviral blockage by telaprevir. Model parameters, including rate constants for viral production, clearance, and effective telaprevir concentration, were estimated from 1) plasma HCV RNA levels of subjects before, during, and after dosing, 2) post-dosing prevalence of plasma variants from subjects, and 3) sensitivity of variants to telaprevir in the HCV replicon. The model provided a good fit to plasma HCV RNA levels observed both during and after telaprevir dosing, as well as to variant prevalence observed after telaprevir dosing. After an initial sharp decline in HCV RNA levels during dosing with telaprevir, HCV RNA levels increased in some subjects. The model predicted this increase to be caused by pre-existing variants with sufficient fitness to expand once available replication space increased due to rapid clearance of wild-type (WT) virus. The average replicative fitness estimates in the absence of telaprevir ranged from 1% to 68% of WT fitness. Compared to the relative fitness method, the in vivo estimates from the viral dynamic model corresponded more closely to in vitro replicon data, as well as to qualitative behaviors observed in both on-dosing and long-term post-dosing clinical data. The modeling fitness estimates were robust in sensitivity analyses in which the restoration dynamics of replication space and assumptions of HCV mutation rates were varied.
- Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers (2012)
- Background: Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly attributable to co-infection with hepatitis B or C. The impact of other risk factors, including prolonged exposure to combined antiretroviral therapy (cART) is poorly understood. Our aim was to determine the prevalence of liver fibrosis and associated risk factors in HIV-infected individuals based on non-invasive fibrosis assessment using transient elastography (TE) and serum biomarkers (Fibrotest [FT]). Methods: In 202 consecutive HIV-infected individuals (159 men; mean age 47 ± 9 years; 35 with hepatitis-C-virus [HCV] co-infection), TE and FT were performed. Repeat TE examinations were conducted 1 and 2 years after study inclusion. Results: Significant liver fibrosis was present in 16% and 29% of patients, respectively, when assessed by TE (≥ 7.1 kPa) and FT (> 0.48). A combination of TE and FT predicted significant fibrosis in 8% of all patients (31% in HIV/HCV co-infected and 3% in HIV mono-infected individuals). Chronic ALT, AST and γ-GT elevation was present in 29%, 20% and 51% of all cART-exposed patients and in 19%, 8% and 45.5% of HIV mono-infected individuals. Overall, factors independently associated with significant fibrosis as assessed by TE (OR, 95% CI) were co-infection with HCV (7.29, 1.95-27.34), chronic AST (6.58, 1.30-33.25) and γ-GT (5.17, 1.56-17.08) elevation and time on dideoxynucleoside therapy (1.01, 1.00-1.02). In 68 HIV mono-infected individuals who had repeat TE examinations, TE values did not differ significantly during a median follow-up time of 24 months (median intra-patient changes at last TE examination relative to baseline: -0.2 kPa, p = 0.20). Conclusions: Chronic elevation of liver enzymes was observed in up to 45.5% of HIV mono-infected patients on cART. However, only a small subset had significant fibrosis as predicted by TE and FT. There was no evidence for fibrosis progression during follow-up TE examinations.
- Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity (2012)
- Aim: Cellular CD81 is a well characterized hepatitis C virus (HCV) entry factor, while the relevance of soluble exosomal CD81 in HCV pathogenesis is poorly defined. We performed a case-control study to investigate whether soluble CD81 in the exosomal serum fraction is associated with HCV replication and inflammatory activity. Patients and Methods: Four cohorts were investigated, patients with chronic hepatitis C (n = 37), patients with chronic HCV infection and persistently normal ALT levels (n = 24), patients with long term sustained virologic response (SVR, n = 7), and healthy volunteers (n = 23). Concentration of soluble CD81 was assessed semi-quantitatively after differential centrifugation ranging from 200 g to 100,000 g in the fifth centrifugation fraction by immunoblotting and densitometry. Results: Soluble CD81 was increased in patients with chronic hepatitis C compared to healthy subjects (p = 0.03) and cured patients (p = 0.017). Patients with chronic HCV infection and persistently normal ALT levels and patients with long term SVR had similar soluble CD81 levels as healthy controls (p>0.2). Overall, soluble CD81 levels were associated with ALT levels (r = 0.334, p = 0.016) and severe liver fibrosis (p = 0.027). Conclusion: CD81 is increased in the exosomal serum fraction in patients with chronic hepatitis C and appears to be associated with inflammatory activity and severity of fibrosis.
- Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study (2012)
- Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease. Systematic analysis of serum IL-22 in relation to morbidity and mortality of patients with advanced liver cirrhosis has not been performed so far. Methods: This is a prospective cohort study including 120 liver cirrhosis patients and 40 healthy donors to analyze systemic levels of IL-22 in relation to survival and hepatic complications. Results: A total of 71% of patients displayed liver cirrhosis-related complications at study inclusion. A total of 23% of the patients died during a mean follow-up of 196 +/- 165 days. Systemic IL-22 was detectable in 74% of patients but only in 10% of healthy donors (P <0.001). Elevated levels of IL-22 were associated with ascites (P = 0.006), hepatorenal syndrome (P <0.0001), and spontaneous bacterial peritonitis (P = 0.001). Patients with elevated IL-22 (>18 pg/ml, n = 57) showed significantly reduced survival compared to patients with regular ([less than or equal to]18 pg/ml) levels of IL-22 (321 days versus 526 days, P = 0.003). Other factors associated with overall survival were high CRP ([greater than or equal to]2.9 mg/dl, P = 0.005, hazard ratio (HR) 0.314, confidence interval (CI) (0.141 to 0.702)), elevated serum creatinine (P = 0.05, HR 0.453, CI (0.203 to 1.012)), presence of liver-related complications (P = 0.028, HR 0.258 CI (0.077 to 0.862)), model of end stage liver disease (MELD) score [greater than or equal to]20 (P = 0.017, HR 0.364, CI (0.159 to 0.835)) and age (P = 0.011, HR 1.047, CI (1.011 to 1.085)). Adjusted multivariate Cox proportional-hazards analysis identified elevated systemic IL-22 levels as independent predictors of reduced survival (P = 0.007, HR 0.218, CI (0.072 to 0.662)). Conclusions: In patients with liver cirrhosis, elevated systemic IL-22 levels are predictive for reduced survival independently from age, liver-related complications, CRP, creatinine and the MELD score. Thus, processes that lead to a rise in systemic interleukin-22 may be relevant for prognosis of advanced liver cirrhosis.
- Aprotinin may increase mortality in low and intermediate risk but not in high risk cardiac surgical patients compared to tranexamic acid and ε-aminocaproic acid - a meta-analysis of randomised and observational trials of over 30.000 patients (2013)
- Background: To compare the effect of aprotinin with the effect of lysine analogues (tranexamic acid and ε-aminocaproic acid) on early mortality in three subgroups of patients: low, intermediate and high risk of cardiac surgery. Methods and Findings: We performed a meta-analysis of randomised controlled trials and observational with the following data sources: Medline, Cochrane Library, and reference lists of identified articles. The primary outcome measure was early (in-hospital/30-day) mortality. The secondary outcome measures were any transfusion of packed red blood cells within 24 hours after surgery, any re-operation for bleeding or massive bleeding, and acute renal dysfunction or failure within the selected cited publications, respectively. Out of 328 search results, 31 studies (15 trials and 16 observational studies) included 33,501 patients. Early mortality was significantly increased after aprotinin vs. lysine analogues with a pooled risk ratio (95% CI) of 1.58 (1.13–2.21), p<0.001 in the low (n = 14,297) and in the intermediate risk subgroup (1.42 (1.09–1.84), p<0.001; n = 14,427), respectively. Contrarily, in the subgroup of high risk patients (n = 4,777), the risk for mortality did not differ significantly between aprotinin and lysine analogues (1.03 (0.67–1.58), p = 0.90). Conclusion: Aprotinin may be associated with an increased risk of mortality in low and intermediate risk cardiac surgery, but presumably may has no effect on early mortality in a subgroup of high risk cardiac surgery compared to lysine analogues. Thus, decisions to re-license aprotinin in lower risk patients should critically be debated. In contrast, aprotinin might probably be beneficial in high risk cardiac surgery as it reduces risk of transfusion and bleeding complications.
- Baseline MELD score predicts hepatic decompensation during antiviral therapy in patients with chronic hepatitis C and advanced cirrhosis (2013)
- Background and Aims: In patients with advanced liver cirrhosis due to chronic hepatitis C virus (HCV) infection antiviral therapy with peginterferon and ribavirin is feasible in selected cases only due to potentially life-threatening side effects. However, predictive factors associated with hepatic decompensation during antiviral therapy are poorly defined. Methods: In a retrospective cohort study, 68 patients with HCV-associated liver cirrhosis (mean MELD score 9.18±2.72) were treated with peginterferon and ribavirin. Clinical events indicating hepatic decompensation (onset of ascites, hepatic encephalopathy, upper gastrointestinal bleeding, hospitalization) as well as laboratory data were recorded at baseline and during a follow up period of 72 weeks after initiation of antiviral therapy. To monitor long term sequelae of end stage liver disease an extended follow up for HCC development, transplantation and death was applied (240weeks, ±SD 136weeks). Results: Eighteen patients (26.5%) achieved a sustained virologic response. During the observational period a hepatic decompensation was observed in 36.8%. Patients with hepatic decompensation had higher MELD scores (10.84 vs. 8.23, p<0.001) and higher mean bilirubin levels (26.74 vs. 14.63 µmol/l, p<0.001), as well as lower serum albumin levels (38.2 vs. 41.1 g/l, p = 0.015), mean platelets (102.64 vs. 138.95/nl, p = 0.014) and mean leukocytes (4.02 vs. 5.68/nl, p = 0.002) at baseline as compared to those without decompensation. In the multivariate analysis the MELD score remained independently associated with hepatic decompensation (OR 1.56, 1.18–2.07; p = 0.002). When the patients were grouped according to their baseline MELD scores, hepatic decompensation occurred in 22%, 59%, and 83% of patients with MELD scores of 6–9, 10–13, and >14, respectively. Baseline MELD score was significantly associated with the risk for transplantation/death (p<0.001). Conclusions: Our data suggest that the baseline MELD score predicts the risk of hepatic decompensation during antiviral therapy and thus contributes to decision making when antiviral therapy is discussed in HCV patients with advanced liver cirrhosis.
- Interobserver agreement of Thyroid Imaging Reporting and Data System (TIRADS) and strain elastography for the assessment of thyroid nodules (2013)
- Background: Thyroid Imaging Reporting and Data System (TIRADS) was developed to improve patient management and cost-effectiveness by avoiding unnecessary fine needle aspiration biopsy (FNAB) in patients with thyroid nodules. However, its clinical use is still very limited. Strain elastography (SE) enables the determination of tissue elasticity and has shown promising results for the differentiation of thyroid nodules. Methods: The aim of the present study was to evaluate the interobserver agreement (IA) of TIRADS developed by Horvath et al. and SE. Three blinded observers independently scored stored images of TIRADS and SE in 114 thyroid nodules (114 patients). Cytology and/or histology was available for all benign (n = 99) and histology for all malignant nodules (n = 15). Results: The IA between the 3 observers was only fair for TIRADS categories 2–5 (Coheńs kappa = 0.27,p = 0.000001) and TIRADS categories 2/3 versus 4/5 (ck = 0.25,p = 0.0020). The IA was substantial for SE scores 1–4 (ck = 0.66,p<0.000001) and very good for SE scores 1/2 versus 3/4 (ck = 0.81,p<0.000001). 92–100% of patients with TIRADS-2 had benign lesions, while 28–42% with TIRADS-5 had malignant cytology/histology. The negative-predictive-value (NPV) was 92–100% for TIRADS using TIRADS-categories 4&5 and 96–98% for SE using score ES-3&4 for the diagnosis of malignancy, respectively. However, only 11–42% of nodules were in TIRADS-categories 2&3, as compared to 58–60% with ES-1&2. Conclusions: IA of TIRADS developed by Horvath et al. is only fair. TIRADS and SE have high NPV for excluding malignancy in the diagnostic work-up of thyroid nodules.
- Prenatal ultrasound screening for fetal anomalies and outcomes in high-risk pregnancies due to maternal HIV infection: a retrospective study (2013)
- Objective. To assess the prevalence of prenatal screening and of adverse outcome in high-risk pregnancies due to maternal HIV infection. Study Design. The prevalence of prenatal screening in 330 pregnancies of HIV-positive women attending the department for prenatal screening and/or during labour between January 1, 2002 and December 31, 2012, was recorded. Screening results were compared with the postnatal outcome and maternal morbidity, and mother-to-child transmission (MTCT) was evaluated. Results. One hundred of 330 women (30.5%) had an early anomaly scan, 252 (74.5%) had a detailed scan at 20–22 weeks, 18 (5.5%) had a detailed scan prior to birth, and three (0.9%) had an amniocentesis. In seven cases (2.12%), a fetal anomaly was detected prenatally and confirmed postnatally, while in eight (2.42%) an anomaly was only detected postnatally, even though a prenatal scan was performed. There were no anomalies in the unscreened group. MTCT occurred in three cases (0.9%) and seven fetal and neonatal deaths (2.1%) were reported. Conclusion. The overall prevalence of prenatal ultrasound screening in our cohort is 74.5%, but often the opportunity for prenatal ultrasonography in the first trimester is missed. In general, the aim should be to offer prenatal ultrasonography in the first trimester in all pregnancies. This allows early reassurance or if fetal disease is suspected, further steps can be taken.


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WND Exclusive: Sheriff shreds anti-gun mayor's excuse for crime spree
WND Exclusive: 'I want to see a cop shoot a white, unarmed teenager in the back'
WND Exclusive: U.S. Navy to Yemen to help Iran?
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WND Exclusive: Common Core's real goal? 'Dumbing down people'
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Clinton ignores questions on Clinton Foundation donations
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Head of Pakistani Taliban killed by U.S. drone strike
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Set of 2 Lint Traps | |||
Easy-to-use, metal mesh lint traps catch threads, hair, lint and other debris before they flow into the washing machine discharge hose and clog plumbing. Includes two plastic fasteners to secure each trap to the discharge hose. Fits most discharge hoses. 2"W and unraveled will stretch up to 9"L. | |||
May We Suggest | |||
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The Secrets of Mary Bowser (Paperback)
Based on a remarkable true story, The Secrets of Mary Bowser is an inspiring tale of one daring woman's willingness to sacrifice her own freedom to change the course of history
All her life, Mary has been a slave to the wealthy Van Lew family of Richmond, Virginia. But when Bet, the willful Van Lew daughter, decides to send Mary to Philadelphia to be educated, she must leave her family to seize her freedom.
Life in the North brings new friendships, a courtship, and a far different education than Mary ever expected, one that leads her into the heart of the abolition movement. With the nation edging toward war, she defies Virginia law by returning to Richmond to care for her ailing fatherand to fight for emancipation. Posing as a slave in the Confederate White House in order to spy on President Jefferson Davis, Mary deceives even those who are closest to her to aid the Union command.
Just when it seems that all her courageous gambles to end slavery will pay off, Mary discovers that everything comes at a costeven freedom.
About the Author
Award-winning author Lois Leveen dwells in the spaces where literature and history meet. Her work has appeared in numerous literary and scholarly journals, as well as "The New York Times", the "Los Angeles Review of Books", "Chicago Tribune", " Huffington Post", "Bitch" magazine, "The" "Wall Street Journal", the "Atlantic", and on NPR. Lois gives talks about writing and history at universities, museums, and libraries around the country. She lives in Portland, Oregon, with two cats, one Canadian, and 60,000 honeybees. Visit her online at LoisLeveen.com and Facebook.com/LoisLeveen.
Praise For…
"Masterfully written, The Secrets of Mary Bowser shines a new light onto our country's darkest history. Balancing fire and grace, the story of Mary Bowser is an ethical journey we won't soon forget, one that takes us from hatred to courage to love."
-Brunonia Barry, bestselling author of The Lace Reader and The Map of True Places
"The Secrets of Mary Bowser is a good old-fashioned historical novel packed with drama, intrigue, love, loss, and most of all, the resilience of a remarkable heroine who forges her own destiny from the first page. What a treat!"
--Kelly O'Connor McNees, author of The Lost Summer of Louisa May Alcott
"Deftly balancing history, romance and adventure, Leveen honors the life and historical importance of a brave, resourceful woman."
-Kirkus Reviews
"Told with clarity, confidence, and courage, The Secrets of Mary Bowser illuminates an untold and important story about slavery, the Civil War, and the role of women in achieving emancipation. A riveting and powerful book."
-Naseem Rakha, internationally bestselling author of The Crying Tree
"Lois Leveen has written a captivating novel...[she] demonstrates considerable skill bringing the historical period to life. Mary's world is nuanced and complicated, but the reader is thoroughly drawn into it, never lost. The narrative voice carries with it a seamless authority, rare in novels of this type."
"Deftly integrating historical research into this gripping tale of adventure, love, and national conflict, Leveen brings Mary to life and evenhandedly reveals the humanity on both sides of America's deadliest war."
-Publishers Weekly
"The Secrets of Mary Bowser is not only fascinating reading, but also historical fiction of the highest caliber."
-Seattle Post-Intelligencer
"Author Lois Leveen's meticulously researched historical fiction is best consumed with sweet tea and a porch swing."
"This novel will sweep you into the world of Mary Bowser without making you feel as if you're sitting in school instead of on the beach."
-Statesman Journal (Oregon)


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Ancient Promises
"The new is in the old concealed; the old is in the new revealed." This famous statement by Saint Augustine expresses the remarkable way in which the two testaments of the Bible are so closely interrelated with each other. The …Read More
In The Beginning
The Bible opens by saying, "In the beginning, God created the heavens and the earth." The purpose of the creation account was not to answer twenty-first century scientific skeptics, but to teach the people of Israel about their God. The …Read More
The Supremacy of Christ
I wonder if it is proper to have a "favorite" book of the Bible. The idea scratches like fingernails on a chalk-board. What would induce us to prefer one portion of the Word of God to another? It would seem …Read More
Hebrews— Does it "Do Anything" For You?
A friend — his face wrinkled in a cheerful grin — described an incident that took place at the end of a conference address I had given recently. One hearer, apparently full of the blessings of the passage I had …Read More
The Final Word of God
Many years ago some of us were facing a potentially negative situation in a small community; one in which we felt great evil could be let loose if there were not divine intervention. An elderly cousin of ours from the …Read More
Jesus and His Apostles: Teaching in Harmony
Have you ever gotten the impression that the teaching of the apostles is at odds with the teaching of Jesus? Sometimes it may seem that way, especially when we see Jesus emphasizing certain things that the apostles don't, and vice …Read More
The Apocalypse
The book of Revelation seems to lend itself to either obsession or neglect. In the first church I attended as a new Christian, our pastor preached through the entire book of Revelation at least twice in a two-year span of …Read More
Choose This Day
Recently, an acquaintance of mine gathered these statistics on the choices available today: 200 cable channels; 255 ways to order a Big Mac; 19,000 possible combinations for coffee at Starbucks and 78,998 for ice cream and toppings at Cold Stone Creamery; …Read More
The Prophets
The post-exilic prophets include Haggai, Zechariah, Malachi, and probably Joel. They convey the message of God for this period of time with cumulative clarity since they come at the end of a long age of prophetic indictment against the people. These …Read More
The Reluctant Prophet
Anyone who has ever attended a Sunday school class knows that Jonah was the man who was eaten alive by a fish and then vomited out three days later. But that's about the extent of most people's understanding of this …Read More
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text: Tuscan Lakes is built on the premise that the dream of a simpler life surrounded by the soothing beauty of the European countryside can be realized every day. The community takes the rich offerings of Tuscany, and places it within reach of every resident who wants to stop planning for "one day" and start living their dream today. Once turning off League City Parkway into Tuscan Lakes, residents transcend time and place as they drive past aqueducts as gracefully aged as their Italian models. Rolling hills and beautiful flowers fill the vast landscape of the 870 - acre masterfully planned, environmentally sensitive community. |


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Blood donors will receive two free tickets to the Oklahoma City Zoo and free health screenings by donating blood. All healthy, Norman-area residents, age 17 and older, are encouraged to donate with Oklahoma Blood Institute (OBI) in the following drives:
"Giving blood is an opportunity to save a life, and it doesn't cost you a penny. The decision you make to spend 30 minutes of your day donating the precious commodity can honestly mean the difference between life and death to a fellow Oklahoman in need," said Norman Regional Health System President and CEO David Whitaker. "We hope every resident in Norman, Moore and the surrounding area will take the time to donate during our three day drive. It's a simple way to make a huge difference."
All donors will have the opportunity to support the Global Blood Fund by forgoing a donor T-shirt. In this way, donors can doubly give – both by donating life-saving blood used locally and by assisting blood centers with supplies needed in developing countries. The fund helps blood centers in developing countries purchase supplies and technology necessary to ensure a safe, local blood supply. Equipment, such as donor beds, digital weighing scales, folding chairs and portable tables, are basic necessities for mobile blood donations, yet are lacking in some, international blood centers.
"August provides a special opportunity for our blood donors to give blood to those in their communities and also help those around the world through the Global Blood Fund," said John Armitage, M.D., Oklahoma Blood Institute president and CEO. "We hope this program goes from being an Oklahoma original to a national standard through other blood centers helping people in more countries."
Donations can be made every 56 days, and OBI provides every drop of blood used by 150 medical facilities in Oklahoma and North Central Texas, including Norman Regional Health System.
According to Bloodlink Foundation, a non-profit charitable trust partner with the Global Blood Fund, it's estimated that six patients from Kenyan medical institutions die from blood-related transfusion complications every hour.
Oklahoma Blood Institute is the eleventh largest, non-profit blood center in America. OBI employs nearly 700 Oklahomans and works with an estimated 800 volunteers and 2,600 drive coordinators. To schedule an appointment to donate blood at any OBI site, call (877) 340-8777, or visit www.obi.org to see a list of blood drives and donor centers in your area.
Contact Kelly Wells
Norman Regional Health System
Office (405) 307.2143
Fax (405) 307.2144
Email email@example.com


text:
I want all, yes even Dekker, but I'm looking forward to Castle Grayskullman the most. He was the perfect idea and represented the 30th anniversary of He-Man better than anything else. Now he just need the castle to be housed in. Finger crossed.
Eternos Palace King Randor
Castle Grayskull Man
All/None of the above
Dekker, Eternos Palace King Randor and Castle Grayskull Man are November's offerings...
Which one of the three (or maybe all!) are you looking forward to the most?
Most Wanted MOTU Classics:
*MotU ~ Multi-Bot/Tung Lashor *PoP ~ Angella/Mermista *200X ~ Roboto/Calix *Filmation ~ Teela Na/Lord Masque
*Play-Sets ~ Snake Mountain/Fright Zone *Vehicles ~ Roton/Land Shark *Beasts ~ Night Stalker/Stridor
I want all, yes even Dekker, but I'm looking forward to Castle Grayskullman the most. He was the perfect idea and represented the 30th anniversary of He-Man better than anything else. Now he just need the castle to be housed in. Finger crossed.
All of them! CGM is just amazing, Randor long time coming, & Dekker gotta love the old tough mentor types.
The Space Mutants are missing something CRITAcal!
Chocolate and Vanilla swiiiirl. Swur-Urrl. -Crazy Eyes
None of them really do it for me. Maybe they'll grow on me when I have them in hand...
He who dies with the most MOTUC wins!
Eh, November would be a boring month if not for the magnificence that is Castle Grayskullman. Dekker is cool, but I have a feeling he won't be able to strike too many poses with that skirt covering the top of his legs. And Randor...well he is what he is. Great for Filmation fans, boring for me. Still, I'll probably keep him for the comedic quality of the look.
"Since you got here by not thinking, it seems reasonable to expect that, in order to get out, you must start thinking." ~ Tock, the Watchdog
Alexx has a blog?! Come on in and check out Toys and Tomfoolery! You won't regret it...until the next morning.
CG is just perfect. The 30th sub-line turned out to be great (with some exceptions).
I've wanted Dekker since the line began, so another big win.
Palace Randor....I wouldn't take him if he was free.
I only want Randor & GCm....I could care less about Dekker....no fan of 200X here.
Recent.... Lizard Man
Wanted.... NA She-Ra, Jitsu....
Needed.... Dragstor
Oh man, did I forget to use these [sarcasm][/sarcasm] again? Sorry....
Check here for my My collection page, MOTU and more!
Castle Grayskullman... YAY
I'm real excited about next year... Ram Man, Jitsu, FFM, Snake Face, Clamp Champ, Karatti, Netossa, NA He-Man, King He-Man!!!
Skeleton-Warriors, Ra-Jar, Spinwit, Rock Golem, Evil Seed, Lord Masque, Prahvus, General Tartaran, Hawke, Slob-Boar, King Agho, Hunga the Harpy, Sh'gora, Masks of Power Demons, Nocturna, Lizzor, Horde Wraiths, Sagitar, Crimson Fury, Lodar, Vizar, Angast, Negator, Melaktha, ABC Giants, Stridor
it's funny, I have to say Castle Grayskullman. He is just pretty suprisingly awesome. Those swords! That Sheild!
Anyway, I already have a place for Eternos Randor, with Marlena, taking over Vintage Randor's spot, who will now go join the rest of the heroic warriors on that shelf.
Dekker...well, he'll be old and standing with the royal family (and 200x Duncan) but I think the young head will be on my Royal Guardsman who is piloting the windraider since I didnt want any non human Guard. I am already using the two human heads, with a third using the black guardsman I painted (hispanic) but now I have a new human head, though I'm considering using him on the variant shelf as just young Dekker, but for that I'd want him in MAn At Arms gear, even though they said not every man at arms wears that outfit.
Anyway, Dekker is cool. but also kinda meh, and randor has a place, but is basically an old figure (though brand new).
Grayskull man has got me with his totally new factor, just like Mattel & Scott had hoped I'd feel with new characters. Excited.
CG man all the way.... Dekker a close 2nd...
couldn't care less about the Randor variant... zzZZzzZZzz
Castle Grayskullman...I have no interest in Double Dekker or Lounging Randor.
"Wheresoever on earth he dwells, man is prey to two weaknesses: the need to pray and the need to love."-Marquis de Sade
"It is not by reasoning or by our understanding that we have received our religion; it is by external authority and command."-Michel De Montaigne
Heretical Vintage Purist and Non-Fan Extraordinaire!
Dekker has my vote. He's the most interesting to me. I like that he has both heads and I'll also be giving him the Clawful accessories from the WP3.
Not to sound like a creepy cheerleader for Uki, but it's nice to know there is at least one person on this forum who is extremely positive & friendly all the time. I don't think I could be that nice even if you paid me. If we ever give out awards for "forum member of the month", Uki gets my vote. -Mr. Shokoti
All in for all three!
King Randor is the king I grew up watching and knowing as the big daddy and I can't wait to have the royal family be whole once more.
Dekker is a great 200x character and although he was not in my first 3 picks (Evil Seed, Dactys, Calix) I'm glad he's in Classics. The Great Unrest storyline is building, all we need up front is KING MIRO!
Castle Grayskull Man, he represents the best part of the 30th line, a great looking character.
King Randor no doubt about...and...Castle Grayskullman...
I'm getting 1 Randor, 2 CGMs, and 3 Dekkers. I'm excited for all of them.
Castle Grayskull Man! Absolutely love that figure
Castle Grayskull Man is the only thing I'm looking forward to this month. I will chop up the other two for parts. Randor's goofy puffy sleeves and dumb elf loafers will be the biggest challenges to rework.
"I reject your Prince Adam and replace him with the original barbarian from the jungle."
Fan of the more Savage side of MOTU? Join the discussion at https://www.facebook.com/groups/savagemasters/
Check out my Custom Action Figure Art at www.InsidiousCustoms.blogspot.com
Follow me on Facebook at facebook.com/InsidiousCustoms
Buy Custom Figures at my Insidious Etsy Store.
I'm anticipatin Dekker most and can't wait for holding him in my hands!
Secret Guardian
Visit my artworks gallery: http://queengrayskull.deviantart.com
and join my group: http://www.he-man.org/forums/boards/...php?groupid=78
For German fans only: http://www.he-man.org/forums/boards/...php?groupid=79


text:
'The Hunger Games' Posters
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Hunger Games trilogy was the first series of books my 13-yr-old daughter and I read together on our new kindles. I think winning these tickets for her and me is the only way I will have an evening when i won't hear any mention of Bruno Mars!
3 years agoby @MarcellusbFlag
Are you ready to read the longest comment thus far? well here it is! i have provided you with a detailed description of EVERYTHING I HAVE BEEN DOING FOR TICKETS!!! i hope that you will see how badly i want this after reading. thanks so much and please let me know if you want proof of anything. i will gladly send you all videos, photos, letters, essays, etc.
i am literally trying all ways of winning tickets to the hunger games premier! TRUST ME WHAT YOU ARE ABOUT TO READ IS A LOT! where to start! i have been emailing the Ellen Degeneres Show for 40+ days straight with pictures, drawings, poems, comics, videos, cheers, letters, essays, etc all hunger games related. i am doing this for 79 days straight. yes i know they havent even announced a contest, but i am doing this because i am obsessed with the books! additionally, i bought a hunger games tshirt online, have all three books (read the series in less than a day and a half, then read them again 3 days later), i have applied to every contest in North America to get premier tickets, but due to geographical restrictions am unable to enter over 40 of the 50 contests Lionsgate released. i cry when i watch the trailers, i have an entire wall full of pictures of Peeta, my Facebook status has a 79 day count down till the movie with a quote each day from the book, i have the same thing going on my bbm, my display picture is hunger game related (its of me a picture of a pita that says Peeta, and my cat as Katniss. the caption says, "tough luck Katniss, i got Peeta first," everyday i go search for every update regarding the movie. i signed up for the capitol website, the facebook "the square" fan group, i have gotten 10 of my friends to read the series, my computer backgorund is of peeta and katniss, i know every word to the trailers, and know everything about all three books. I have recently started attempting to email every single person involved in the production of the movie and from the Ellen Show asking for help. I have even started calling from Toronto (one of them being Gary Ross himself). I have created a professional portfolio that has everything i have done to this date. I have the support of several companies hosting Hunger Games Contests in the USA on their facebook pages (Alliance Films, Crushable, NetFix [made me a spotlight on their HG fan page], etc). They all know how dedicated I am and how much i want tickets. My most recent attempt, in the past 2 days has been emailing LA newspapers asking if they would write an article about me and what i am trying to do. my hope is that it will convince someone out there that i am really trying. I was the first person in Guelph, Ontario (where i go to university) to purchase the Hunger Games Official Illustrated Movie Companion! i am basically CRAZY CRAZY CRAZY OBSESSED WITH THIS SERIES AND AM BENDING OVER BACKWARDS DOING EVERYTHING HUMANLY POSSIBLE TO WIN EVEN ONE TICKET TO THE PREMIER! I have posted several hunger games related youtube videos, i am planning on painting my nails too look like flames for the premier, and i cant attend the midnight screening on the 23td of march, because i have a cheerleading competition in florida and wont be able to see it that night which literally kills me inside so this is my ONLY WAY to see it!!!!!!! if you are looking for the worlds most obsessed hunger games fan, I SWEAR THAT YOU SHOULD LOOK NO FURTHER! i am a die hard fan, with insane love for the books. just so you know, i have ficticiously married peeta mellark because he is the hottest most romantic person alive! please please please please please x100000000000000000 help me make my dream come true! i never ask for anything and to me this would be a miracle! as effie trinket says, "may the odds be ever in MY favour" i am the biggest hunger games fan there is! i am having anxiety attacks over this on a daily basis and i am already terrified that i wont get tickets. i swear i would break down if i didnt. I doubt you will receive an application from anyone else who has done nearly as much as i have. i doubt anyone has tried to directly contact the Ellen Show or Gary Ross personally. Or someone who has been at this for 40+ days since they finished the books. I have done all this in 2 months. i am begging you to make my dream come true3 years agoby @Lauren-MorrisonFlag


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Take your wedding decor to the next level with professional wedding lighting. Brides and other wedding professionals love the wedding services in Here Comes The Guide. How do we know? We ask—and if we don't hear raves, we don't consider them Certified By The Guide.
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Top Definition
These are creatures who we humans may or may not believe in. They can live anywhere, look like anything, and possibly do things we never dreamed was possible. most of the animals are related to magic which is why most humans have never seen any.
the yeti, loch ness monster, bigfoot, unicorns, goblins, sprites, fairies, etc. are all examples of mystical creatures.
por Mrs. Cullen
05 de Julho de 2008
1 more definition
Mystical creature was a little mystical creature the size of my penis. Mystical is one of many alter ego's of the famous toxic mike, (aka mysterious). Mystical was grown up in a clean house hold, every thing was very tidy, and he loved to play with his brothers like hs liked to bone his mom up the ass. His mother was a huge boner who liked to eat chodes. One night her tampon leaked and it went into mystical's mouth. Mystical didn't like the taste of blood but he really like the taste of the tampon. Mystcial procceeded to chew like it was bublicious gum! MMMMMMMM MMMMMMM good, it was as tasty as cambells soup! Mystical then contracted "Toxic shock sydrome" and died on impact.
RIP: Biggies, tupac, MYSTICAL CREATURE!
por Mysterious Passion
07 de Maio de 2004


text:
Mauer, 31, suffered the injury in the fourth inning against the Kansas City Royals on Tuesday night.
Mauer, who has hit safely in 12 straight games, is hitting .271 with 17 doubles, two homers and 28 RBIs in 76 games this season.
To take the place of Mauer on the 25-man roster, the Twins recalled first baseman/outfielder Chris Colabello from Triple-A Rochester.
Colabello played in 36 games for Rochester, hitting .275 (36-for-131) with eight doubles, six home runs and 27 RBIs. He played 40 games with the Twins earlier this season, hitting .232 (35-for-151) with 10 doubles, four home runs and 30 RBIs.


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Please note that the percentages above are meant to guide you, but they do not equate to the exact probabilities (to score for example) used in the match engine.
As a Supporter you can view ratings graphs, which give you a quicker and more detailed overview on how ratings developed during the match - making it easier for you to analyze your matches.
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Yakima Racks
Quickback 3 Trunk Mount
In Stock Product Number: 16676
The Quickback 3 Trunk Mount by Yakima is a car friendly, easy-to-set-up trunk rack that holds three bikes with no problem. Premium Tri-Padded feet and coated padded metal buckles protect your car's paint job. A narrow arm design fits a wide variety of bikes and its SwitchBlade anti-sway cradles eliminate bike-to-bike contact so your bike can keep its paint job too. Integrated bottle opener for those after ride hydration beverages.
* This product does not qualify for shipping to all countries.
- Carries 2 bikes
- Narrow arm design fits a wide variety of bikes
- Arms quickly fold down when not in use
- Premium Tri-Padded feet and coated padded metal buckles protect your vehicle's paint job
- SwitchBlade antisway cradles eliminate bike to bike contact
- 6 labeled strap system tell you when everything is in place
- Compatible with most factory spoilers
- Includes glass hatch hooks for glass trunk or gate mounts
- Passive security system included with a steel reinforced strap that goes into the trunk
- Integrated bottle opener
Gender: Unisex
Weight: 14.8 lbs.
Season: N/A
Vendor ProductId: 8002622
Review ProductId: 16676