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Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
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- Stem cell transplants from related donors (allogenic stem cell transplants) can be used to treat individuals with certain kinds of severe blood diseases or cancers, such as severe anemia. Allogenic stem cell transplants encourage the growth of new bone marrow to replace that of the recipient. Because stem cell transplants can have serious complications, researchers are interested in developing new approaches to stem cell transplants that will reduce the likelihood of these complications.
- By reducing the number of white blood cells included in the blood taken during the stem cell collection process, and replacing them with a smaller amount of white blood cells collected prior to stem cell donation, the stem cell transplant may be less likely to cause severe complications for the recipient. Researchers are investigating whether altering the stem cell transplant donation procedure in this manner will improve the likelihood of a successful stem cell transplant with fewer complications.
- To evaluate a new method of stem cell transplantation that may reduce the possibly of severe side effects or transplant rejection in the recipient.
- Recipient: Individuals between 8 and 80 years of age who have been diagnosed with a blood disease that can be treated with allogenic stem cell transplants, and who have a related donor to provide the stem cells.
- Donor: Individuals between 2 and 80 years of age who are related to the recipient and are eligible to donate blood.
- All participants will be screened with a physical examination and medical history.
- Donors will undergo an initial apheresis procedure to donate white blood cells.
- After the initial donation, donors will receive injections of filgrastim to release bone marrow cells into the blood.
- After 5 days of filgrastim injections, donors will have apheresis again to donate stem cells that are present in the blood.
- Recipients will provide an initial donation of white blood cells to be used for research purposes only.
- From 7 days before the stem cell transplant, participants will be admitted to the inpatient unit of the National Institutes of Health Clinical Center and will receive regular doses of cyclophosphamide, fludarabine, and anti-thymocyte globulin to suppress their immune system and prepare for the transplant.
- After the initial chemotherapy, participants will receive the donated white blood cells and stem cells as a single infusion.
- After the stem cell and white blood cell transplant, participants will have regular doses of cyclosporine and methotrexate to prevent rejection of the donor cells. Participants will have three doses of methotrexate within the week after the transplant, but will continue to take cyclosporine for up to 4 months after the transplant.
- Participants will remain in inpatient care for up to 1 month after the transplant, and will be followed with regular visits for up to 3 years with periodic visits thereafter to evaluate the success of the transplant and any side effects.
Condition | Intervention | Phase |
Severe Aplastic Anemia MDS (Myelodysplastic Syndrome) |
Device: Miltenyi CD34 Reagent System Other: Donor derived G-CSF mobilized PBC |
Phase 2 |
Study Type: | Interventional |
Study Design: | Allocation: Non-Randomized Endpoint Classification: Safety/Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment |
Official Title: | Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-Cells |
- Primary endpoint of this study is chronic GVHD by one year. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
- Transplant related mortality, engraftment, degree of donor-host chimerism, incidence of acute and chronic graft versus host disease (GVHD), transplant related morbidity and overall survival. [ Time Frame: Cumulative ] [ Designated as safety issue: No ]
Estimated Enrollment: | 110 |
Study Start Date: | July 2010 |
Estimated Study Completion Date: | June 2017 |
Estimated Primary Completion Date: | June 2017 (Final data collection date for primary outcome measure) |
Device: Miltenyi CD34 Reagent System
Allogeneic hematopoietic stem cell transplantation (aHSCT) can cure patients with a variety of bone marrow failure syndromes (BMFS) including severe aplastic anemia (SAA), paroxysmal nocturnal hemoglobinuria (PNH) or myelodysplastic syndrome (MDS) associated with cytopenias. Patients with BMFS have traditionally been transplanted with bone marrow (BM) as a stem cell source. Although chronic graft versus host disease (cGVHD) occurs less commonly with BM compared to filgrastim (G-CSF) mobilized peripheral blood stem cell (PBSC) transplants, BM allografts have lower CD34+ progenitor cell numbers, which increases the risk of graft rejection in heavily transfused BMFS patients to 15-20 percent. To overcome this risk, our group developed a novel transplant approach for patients at high risk for graft rejection that utilized cyclophosphamide, fludarabine and anti-thymocyte globulin (ATG) conditioning followed by infusion of a CD34+ cell rich, T-cell replete G-CSF mobilized PBSC allograft. Remarkably, in 56 consecutive BMFS patients who had multiple risk factors for graft rejection who underwent this transplant approach graft rejection did not occur, with all patients achieving complete donor lymphohematopoietic chimerism. Unfortunately, recipients of G-CSF mobilized PBSC had a higher incidence of chronic GVHD than has historically been observed with BM transplantation (72 percent vs. 50 percent cumulative incidence of cGVHD at 1 year respectively). G-CSF mobilized PBSC transplants contained approximately a 20 fold higher dose of T-cells that had undergone a TH- 2 type cytokine polarization, a factor which likely contributed to this high incidence of cGVHD. In this protocol, we attempt to prevent graft failure and to reduce the incidence of cGVHD by transplanting high numbers of CD34+ selected PBSC co-infused with a reduced dose of non-mobilized donor T-cells that have not undergone a TH-2 cytokine polarization.
Subjects with BMFS at high risk for graft rejection will undergo allogeneic stem cell transplantation from an HLA identical sibling using the identical conditioning regimen utilized in protocol 99-H-0050. Using the Miltenyi CliniMACs system, recipients will receive an allograft on day 0 containing donor CD34+ cells that have been positively selected and T-cell depleted following G-CSF mobilization (goal CD34+ cell dose of 5 times 10(6) CD34+ cells /kg recipient) combined with 2 times 10(7) cells/kg of non-mobilized CD3+ T-cells previously collected and cryopreserved from the same donor by apheresis prior to G-CSF mobilization.
Primary objective: To evaluate whether administering a CD34+ selected, T-cell depleted peripheral blood stem cell graft with a concomitant infusion of non-mobilized donor T-cells at a dose that matches the T-cell dose that is infused in historical bone marrow transplant cohorts will reduce the incidence of cGVHD at 1 year to that observed with a conventional bone marrow transplant (50 percent) without increasing the risk of graft failure. This trial design will allow the trial to stop early if it is unlikely that we have reduced the proportion of one year cGVHD to 50 percent or if the combined event rate for failed donor engraftment or treatment related mortality (TRM) at day 100 exceeds 20 percent.
The primary endpoint of this study will be cGVHD at day 365.
Secondary end points include transplant related mortality, engraftment, degree of donor-host chimerism, incidence of acute and chronic graft versus host disease (GVHD), transplant related morbidity and overall survival. Health related quality of life will also be assessed as a secondary outcome measure pre-transplant, 30 and 100 days post transplant and every 6 months until 5 years post transplant.
Ages Eligible for Study: | 6 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Patients diagnosed with one of the following hematologic diseases which are associated with reasonable longevity, shown to be curable by allogeneic BMT but where concern for a high procedural mortality with conventional BMT may delay or prevent such treatment:
- Paroxysmal nocturnal hemoglobinuria (PNH) associated with life-threatening thrombosis, and/or cytopenia, and/or transfusion dependence and/or recurrent and debilitating hemolytic crisis
- Severe aplastic anemia (SAA) or pure red cell aplasia (PRCA [acquired or congenital]) associated with transfusion dependence and/or neutropenia in patients who are not candidates for, or who have failed immunosuppressive therapy
Refractory anemia (RA) or RARS MDS patients who have associated transfusion dependence and/or neutropenia.
Ages 6 to 80
Availability of HLA identical or single HLA locus mismatched family donor
Genetic testing for genes associated with bone marrow failure syndromes (BMFS) - telomere length, TERC and TERT mutations was done on protocol 04-H-0012 at the NIH or performed elsewhere prior to enrolling to protocol 04-H-0012.
Recipient: any of the following
Major anticipated illness or organ failure incompatible with survival from PBSC transplant
Diffusion capacity of carbon monoxide (DLCO) less than 40 percent predicted
Left ventricular ejection fraction less than 40 percent (evaluated by ECHO) or less than 30 percent (evaluated by MUGA)
Serum creatinine greater than 2.5mg/dl or creatinine clearance less than 50 ml/min by 24 hr urine collection
Serum bilirubin greater than 4 mg/dl, transaminases greater than 5 times the upper limit of normal
Pregnant or lactating
Fanconi s anemia
ECOG performance status of 3 or more (See Bone & Marrow Transplant Consortium Supportive Care Guidelines for HSCT Recipients)
Other malignant diseases liable to relapse or progress within 5 years, with the exception of a separate hematologic malignancy where allogeneic stem cell transplant has been shown to be potentially curative.
Inability to comprehend the investigational nature of the study and provide informed consent. The procedure will be explained to subjects age 8 -17 years with formal consent being obtained from parents or legal guardian.
HLA identical or single HLA mismatched family donor
Age greater than or equal to 6 and less than or equal to 80 years old
Weight 19 kg or more
Genetic testing for genes associated with bone marrow failure syndromes (BMFS) - telomere length, TERC and TERT mutations was done on protocol 04-H-0012 at the NIH or performed elsewhere prior to enrolling to protocol 04-H-0012.
Donor: any of the following
Pregnant or lactating
Unfit to receive filgrastim (G-CSF) or undergo apheresis (history of stroke, MI, unstable angina, uncontrolled hypertension, severe heart disease or palpable spleen)
HIV positive (donors who are positive for HBV, HCV or HTLV-I/II, T.cruzi [Chagas] may be used at the discretion of the investigator following counseling and approval from the recipient)
Sickling hemoglobinopathies including HbSS or HbSC. Donors with HbAS are acceptable
Inability of donor or guardian of donor to comprehend the investigational nature of the study and provide informed consent.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01174108
Contact: Elena J Cho | (301) 594-8013 | firstname.lastname@example.com |
United States, Maryland | |
National Institutes of Health Clinical Center, 9000 Rockville Pike | Recruiting |
Bethesda, Maryland, United States, 20892 | |
Contact: For more information at the NIH Clinical Center contact Patient Recruitment and Public Liaison Office (PRPL) 800-411-1222 ext TTY8664111010 email@example.com |
Principal Investigator: | Richard W Childs, M.D. | National Heart, Lung, and Blood Institute (NHLBI) |
Additional Information:
Responsible Party: | National Institutes of Health Clinical Center (CC) ( National Heart, Lung, and Blood Institute (NHLBI) ) |
ClinicalTrials.gov Identifier: | NCT01174108 History of Changes |
Other Study ID Numbers: | 100154, 10-H-0154 |
Study First Received: | July 31, 2010 |
Last Updated: | March 27, 2015 |
Health Authority: | United States: Federal Government |
Keywords provided by National Institutes of Health Clinical Center (CC):
Myelodysplastic Syndrome (MDS) Severe Aplastic Anemia Pure Red Cell Aplasia |
Paroxysmal Nocturnal Hemoglobinuria (PNH) Miltenyi CD34 Reagent System Allogeneic Stem Cell Transplant |
Additional relevant MeSH terms:
Anemia Anemia, Aplastic Anemia, Hemolytic Hemoglobinuria, Paroxysmal Myelodysplastic Syndromes Pancytopenia Preleukemia |
Syndrome Bone Marrow Diseases Disease Hematologic Diseases Neoplasms Pathologic Processes Precancerous Conditions |
ClinicalTrials.gov processed this record on May 05, 2015


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DoD, VA accelerate schedule for integrated health record
Wednesday - 2/6/2013, 3:05pm EST
The Departments of Defense and Veterans Affairs are revamping their plan to integrate the electronic health records used by their two large medical systems, promising the new approach will deliver capabilities sooner and for less money.
Defense Secretary Leon Panetta and VA Secretary Eric Shinseki announced the revised program and revised timeline following one of their regular meetings on the topic of better integrating services for veterans and military members. Under the new approach, Panetta said, the integrated electronic health record originally scheduled to reach full capability in 2017 will offer up at least partial functionality by early 2014.
"Rather than building a single integrated system from scratch, we will focus our immediate efforts on integrating VA and DoD health data as quickly as possible, by focusing on interoperability and using existing solutions," he said. "This approach is affordable, it's achievable, and if we refocus our efforts, we believe we can achieve the key goal of a seamless system for health records between VA and DoD on a greatly accelerated schedule."
Focus on 'quick wins'
The new plan still calls for VA and DoD to merge toward a common software platform by 2017, but in the short-term, they'll focus more on standardizing the data their present-day systems use than on standardizing software.
Roger Baker, VA's chief information officer, said the departments decided to focus on "quick wins:" By 2014, VA and DoD plan to be able to exchange the most important types of data — seven different "data domains" that are accessed by clinicians in the two departments on a day-to-day basis, including lab results, drug information, allergies and clinical notes.
"It will be exchanged on all patients, and most critically, it will be in a standard data format so that the data looks exactly the same between the two systems by 2014," he said. "In 2017, the goal is that we're exchanging all patient information, and there are more than 40 domains when you think about everything to make common between the two organizations. Probably even more critically when you think about 2017 is that the software we use will be highly common at that point."
Another change — by the end of this year, the two departments will begin sharing a common graphical user interface in clinical settings each of them operate. Dr. Jonathan Woodson, the assistant secretary of Defense for health affairs, said the 2013 rollout will begin with seven DoD and VA wounded warrior polytrauma centers.
"These patients are exchanged back and forth between the two systems quite regularly. There's a lot of interaction between them, so we felt this was one of the best places to demonstrate the utility of this new graphical user interface that allows us to look at both sets of records at the same time," he said.
Scrapping plan for new system built from scratch
Officials said the reason the two departments will be able to deliver capability sooner at a lower price is that they've jettisoned their original plan to build a new, joint system from the ground up, an approach they originally estimated would cost $4 billion by 2017.
Instead, Baker said, they've agreed that each department would use an existing "core technology" as their starting point. VA will build from its existing VistA health record system, but DoD has yet to select the technology that will form its core.
"Our goal though is to make certain that we're creating a single medical record for all patients, so that a clinician seeing a patient from a DoD or VA system has all medical information available to treat that individual from the moment they raise their right hand to the moment they're honored on one of our national shrines," he said.
But for the most part, the departments say the new approach won't involve throwing the work they've already done out the window.
Beth McGrath, DoD's deputy chief management officer, said most of the work to date has involved creating common requirements and data standards, developing a shared "enterprise service bus" that all health IT applications will eventually connect to, and bringing their IT networks closer together. Those are all efforts that will still come into play between now and 2017.
"The VA, for example, agreed two years ago, and has moved out quite smartly on moving their systems and their data into the (Defense Information Systems Agency) data centers, to make sure we've got interoperability across the enterprise," she said. "It's important to remember that the approach we're taking remains fundamentally consistent."


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text: The Clemson University Student Handbook provides important information on institution policies, people, campus activities, tradition, and organizations. Every effort has been made to provide current and accurate information in this publication; however, the administration reserves the right to alter, amend, or abolish its rules, regulations or policies at any time. For the most accurate and up-to-date information, please consult this website or individual departments. Should you require additional information, please contact any of the resource persons listed in this Student Handbook or the Campus Directory.


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JEGS carries a good selection of flex plate covers, or inspection covers for automatic transmissions. Don't run without an inspection plate. You need to have one to cover up your ring gear to keep dirt out. TH400 & TH350 inspection covers are our most popular! We have a number of cool looking flex plate covers to choose from ready to ship to your door! |
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Cotton Fleece Blanket and Throw from Germany
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Toast your squad with this NFL® stainless steel water bottle from Great American Products. It includes a screw-top lid, as well as a carabiner clip. A high-quality metal team logo adorns the side. Perfect for the health-conscious fan, the container is BPA-free.
- 26oz. Capacity
- BPA-free design
- Carabiner clip
- Decorated with a high-quality metal team logo
- Made in USA
- Officially licensed
- Screw-top lid
- Stainless steel water bottle
Special event items are produced by manufacturers only after the outcome of a game
or event. These are advanced sale items and will ship immediately after they are
received in our warehouse.
Manufacturer direct items are shipped directly from the manufacturer. These items
are not available for international or expedited shipping.
Customized items can be personalized with options such as your name, your favorite
number, and/or designs. Some options may be limited by league rules.


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CCC is neither qualified nor licensed to provide financial or tax advice. To the extent answers to questions below deal with Federal or State income tax information, any information provided is not intended or written by CCC to be used, and cannot be used by any taxpayer, for the purpose of avoiding any penalties that may be imposed under the Internal Revenue Code. Information from CCC relating to Federal tax matters may not be used in promoting, marketing or recommending any entity, investment plan, or arrangement to any taxpayer.
What is a 403(b) Plan?
In public educational organizations like School Districts and Community Colleges, 403(b) Plans generally serve as supplemental retirement savings plans designed to supplement retirement benefits available from State pension plans and Social Security. The IRS provides a Summary of 403(b) Plan Basics page and a 403(b) Plan Brochure for Employees on its website. Many of the topics covered there are treated in even greater detail on this CCC website, whereas some other topics covered there are not applicable to public employers.
What is a 457(b) Plan?
457(b) Plans are supplemental retirement savings plans similar to 403(b) Plans, and are called Deferred Compensation Plans (DCP for short)for state and local government employees (including public school employees). Some public school employers offer 457(b) DCPs and others do not. Check your employer's section of this CCC website for additional information about 457(b) DCPs or Click here for frequently asked questions about 457(b) Plans.
Am I eligible for catch-up contributions?
Catch-up provisions are subject to availability under your employer's plan (please see your employer's page for additional details).
If you are age 50 or over by the end of the current year, you are eligible to use the Age 50 Catch-up (if this catch-up is available under your employer's plan).
There are other catch-ups available to some employees who meet very specific eligibility requirements. If you will complete at least 15 years of full time service with your current employer by the end of the calendar year, you may be eligible additional amounts under the 403(b) 15 Years of Service Catch-up (if this catch-up is available under your employer's plan). For 457(b) plans, if this year is one of the last three years before your normal retirement age you may be eligible for the 3 Year Catch-up (if this catch-up is available under your employer's plan). For these catch-ups, determination of eligibility requires collection and evaluation of historical service, payroll, and contribution data for all periods of employment back to your initial hire date from your employer. If you wish to defer more than the basic elective deferral limit, or the basic limit plus the Age 50 Catch-up amount for participants turning 50 or better by the end of the year, contact CCC and we will request the required data from your employer to make a determination. (Please note: data requests of this nature make take time to fulfill and will be subject to availability.)
Click here for more details concerning contribution limits.
What are my 403(b) or 457(b) rollover options and the taxation concerns connected to distributions from my account(s) once I have obtained a qualifying event for distribution?
When taking a rollover or distribution from a 403(b) or 457(b) account, one must consider all options available to them and the tax consequences associated with those options. Most vendors provide a notice called a "402(f)" that describes the various rollover options and the applicable taxes associated with distributions and rollover options that comes as a part of or addendum to the vendor's distribution and rollover forms. Usually the participant's authorization section of one of these forms requires the participant to attest to the fact they have read the notice pertaining to taxation and understand the applicable tax consequences of the transaction they are submitting. (Please note: the IRS provided generic model language for 402(f) Notice in 2009 (Notice 2009-68), this model language is viewable here.) CCC strongly encourages participants to seek the advice of a qualified and trusted financial advisor and/or tax consultant concerning investment and distribution choices.
When am I considered "severed from employment" as it pertains to my 403(b) or 457(b) account(s)?
Severance is defined as a complete severance from any employment relationship with the Employer sponsoring the 403(b) and/or 457(b) plan.
CCC has created guidance for employers to determine if an employee meets the criteria to be considered "severed from employment". This document is available here.
My employer is offering a post-severance Early Retirement Incentive (ERI) program. If I decide to participate, will I have the option to defer any portion of these payments into my 403(b) or 457(b) accounts?
No, post-severance deferrals from ERI stipends are not allowed.
If you are an employer considering an ERI program, please contact CCC as the rules concerning these programs are complex and failure to appropriately set up this program may have unintended consequences.
Can I take a hardship withdrawal from my 403(b) account?
Hardship Distributions are only available under certain circumstances and require documentation. Note: hardship transactions are subject to availability under your employer's plan (please see your employer's page for additional details). Please visit our Hardships page for details on the circumstances under which these distributions are available and the CCC Hardship Request Form.
I have received a check from my investment provider (or parent entity) that is payable to my Employer pertaining to a legal settlement. What should I do with this check?
Some of these checks appear to be payable to the Employer with no mention of the Employee, while others appear to be payable to the Employer for the benefit of the Employee. The best information available on this issue may be found on the settlement administrator's website or by calling the settlement administrator's service center, this information should appear in the letter or checkstub that accompanied the check you received.
Does CCC provide financial or investment advice?Where should I go for financial or investment advice?
No. CCC provides only compliance monitoring and plan administration services to its client Employers.You may wish to check out our useful links page for information on researching investment products and services.
Does PERS affect my 403(b) or 457(b) contributions?
The general answer is no. You are allowed to contribute right up to your elective deferral limit into either or both of the 403(b) and 457(b) plans, irrespective of employee and employer PERS contributions.
The only situations in which PERS contributions impact your ability to contribute to 403(b) and/or 457(b) plans is when your gross salary is fairly low (about $13,000 per year for a single plan or $26,000 per year for both plans during 2004). Since contributions are limited to 100% of compensation, if employee PERS contributions are pre-tax salary deductions, they reduce your compensation. Consequently, they reduce the amount you can contribute to the 403(b) and/or 457(b) plans.
What is the process to add a provider to my employer's list of vendors?
The process for adding a "provider" (our terminology is "Vendor with an Active Payroll Slot") may be found in Section 1.3(b) of your employer's 403(b) Plan Document on the CCC website. To get there, click on Employee Entrance button up top and then your Employer. Then click the green menu item: 403(b) Plan Document.
Can I move 403(b) funds to another Vendor? to an IRA?
If contract exchanges are allowed under your employer's plan, 403(b) funds can be exchanged with and to a new vendor's 403(b) account to an eligible vendor. Rollovers out of the plan to another eligible retirement account (such as an IRA) are only possible if you are eligible for a distribution, typically by attaining age 59-1/2 or severing employment depending on the rules of of your employer's plan Please visit your employer's page for additional information.
Is it possible to use my 403(b)/457(b) account to purchase pension plan Permissive Service Credit?
Oregon: Effective 9/1/2011, the purchase of Permissive Service Credit will be allowed under Oregon Law. See Senate Bill 399 for documentation.
Prior to 9/1/2011, Oregon PERS requires use of after-tax dollars to purchase permissive service credit, the only way to use 403(b) or 457(b) for purchasing permissive service credit in Oregon PERS is to obtain funds via a loan or a distribution. Additional background information on Permissive Service Credit Transfers can be found here.
Washington: The answer is yes. See Senate Bill 399 for documentation.
Please note that to purchase Permissive Service Credit, this transaction must be an optional feature allowed under your employer's plan.
I have received a package of corrective distribution documents from CCC informing me that I exceeded my elective deferral limit last year and must sign and return the documents for further processing and report the excess deferral amount on my tax return for last year. Please explain?
Carruth Compliance Consulting, Inc. (CCC) serves as Third Party Administrator (TPA) for the 403(b) Tax Sheltered Annuity (TSA) Plan of your employer. One service CCC provides is testing contributions for compliance with IRS imposed contribution limits.
The following steps were taken by CCC in attempts to obtain sufficient human resources, payroll, and vendor remittance data to verify your eligibility for up to $3,000 in additional elective deferrals under the 15 Years-of-Service Catch-up Provision found in Section 402(b)(7) of the Internal Revenue Code:
1) We requested that your employer provide data as far back as such data were available on current systems;
2) Either we didn't receive data at all and had to work with ad hoc information provided by your employer or we received insufficient data to determine eligibility for catch-up contributions;
3) When data received in Steps 1) and 2) were insufficient to determine eligibility, we requested from your employer either copies of your historical W-2 Forms or copies of your historical Salary Reduction Agreements;
4) Since data received in Steps 1), 2), and 3) have proved to be insufficient to determine eligibility, the only options remaining are for you to provide copies of your W-2 Forms or copies of your year-end check stubs to verify historical contributions.
Absent receipt of either historical W-2 Forms or historical year-end check stubs, we must request that you sign the corrective distribution documents and return them to us for submission to your vendor by March 15th, so that the corrective distribution may be made by April 15th.
Neither your employer nor CCC can force you to sign and return the corrective distribution documents. However, we need to inform you that based on information CCC has been provided, you have exceeded your elective deferral limit. If you fail to sign and return to CCC the corrective distribution documents, your tax return for the year the excess occurred is audited by the IRS, and the IRS finds that you did, in fact, exceed your elective deferral limit and failed to process a corrective distribution, then the excess deferral will be taxable during the year the excess occurred (likely requiring you to file an amended tax return) and the excess deferral will be taxable again when it is distributed (resulting in double taxation of the excess deferral that was not timely distributed).
Are my 403(b) and/or 457(b) elective deferrals subject to FICA (Medicare and Social Security) withholdings?
Yes. Employee contributions to both 403(b) and 457(b) plans are subject to FICA withholdings.


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Laurie D.Harrisburg,PennsylvaniaTerrific Experience With Folicaterrific product for my short spiked hair and lightening fast delivery too!!!!!!!!!!!posted Feb 25, 2011Link to this post
Ashleen FarallelVancuver, CanadaLooking Goodi bought this product a week ago and i used it the first day i got it and to my suprise it was not sticky and it made my hair shiny the whole day but not with the effect of greasy looking and i have very puffy hair so it didnt manage to make my hair stay flat down but it did much better than what other products did and i aslo love the smell :)posted Jan 21, 2010Link to this post
TanjiaAlberta, CanadaGreat Gel For Curly HairI use this gel to help hold my curls together. It does not dry out my hair or make it crispy or crunchy. It holds the curls together really well and my hair still feels soft. I really like it!posted Jan 3, 2010Link to this post
DreadlocksbyrandiNycNot So GoodI use to buy got2b kicked up hard jelly that was fab cant find anything as great as that tried this didnt hold hair down to well at all bought 6 because it said spiked up meaning it holds really well, well it doesntposted Jun 9, 2009Link to this post
Lauren PluguezRichmond Hill, NYGot2b Products Do Work!I am a girl like most who have combination hair. My category is under: Its wavy and frizzy. In the summer, I like to wear my hair natural because alot of my friends told me, my hair was great to play with. So I bought this product after someone at a parade told they used it. I really like it! It dries fast, leaves no frizzies, light in weight and still playfull after hours without any fly aways. Even though the product is very sticky. The best part is no break out around the face. (For me at least.) Alcohol i believe is in this product but hasnt damaged my hair yet. Good Luck!posted Aug 20, 2008Link to this post
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Greg Von Doersten
Greg Von Doersten specializes in expeditions, adrenaline sports, and mans relationship and interaction with the natural world,Von Doersten has traveled the globe while pursuing innovative, iconic images that both excite the viewer and tell a story. In the lastdecade, Greg has performed advertising assignments from international clients such as Benetton Sport Systems, Dewar's, Fila, The North Face,Hilton Resorts, Molson Beer, Swatch Watches and W.L. Gore; hes also completed feature length assignments for Conde Nast Traveler, ESPN themagazine, Mens Journal, National Geographic Adventure, GQ, and Outside Magazines. Whether chasing paddlers running the biggest rapids in theworld on the Congo River or executing a major advertising campaign for Dewar's, Greg continues to create images that exceed his clients'expectations and creative goals.
Website: Greg Von Doersten


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Iris' Emolga is the third Pokémon Iris caught during her travels through Unova with Ash.
Emolga first appears in the opening of Emolga the Irresistible!, where she is shown using Attract on a group of Patrat in order to get their food, making her seem greedy. She meets Axew after she catches the fruit he was chasing down a hill. She acts kind towards Axew, so she could obtain more fruit from Iris. However, after being smothered by Bianca, she runs away into the forest.
Axew wanted to share his fruit with Emolga, so Iris pursued it. However, Emolga ran off again after Bianca attempted to catch it. Soon after, Iris, Axew and Emolga fall down a cliff and into a forest filled with irate Swoobat. Once the Swoobat were defeated and everyone was safe, the group returned to their camp, where Emolga flew into Iris' arms and accepted capture, much to Bianca's disappointment.
In BW028, she is used by Iris to battle Bianca's Pignite and Minccino. However, she was not keen on battling and so kept using Volt Switch to send out other Pokémon in her place. Strangely, not only does she swap with members of Iris' team, she also sends out Cilan's Pansage and Ash's Snivy. Emolga then charms her Trainer after she is scolded for using an attack without being commanded. She then flies away and Iris finds her in a tree.
Once again showing her gluttonous nature, Emolga used Attract on Ash's Pokémon so she could get their food. It soon becomes apparent that Snivy is not impressed by Emolga's attitudes and a mutual disliking seems to develop between the two. However despite this, Snivy still rescued Emolga, as well as Oshawott and Axew from a wild Simisear. The two then teamed up to rescue Simisear from a falling rock. It seems then that their disliking has come to a halt, but the two are seen looking away from each other quickly after catching each other's eye.Known moves
Move | Episode |
Attract | Emolga the Irresistible! |
Discharge | Emolga the Irresistible! |
Hidden Power | Emolga the Irresistible! |
Volt Switch | Emolga the Irresistible! |
+ indicates this Pokémon used this move recently.* - indicates this Pokémon normally can't use this move. |
Moves |
- Emolga is the first Pokémon Iris has been seen capturing, she obtained Axew and Excadrill before meeting Ash.
- Emolga is the first female Pokémon to be caught by Iris.
- Emolga has an obsession with food, similar to May's Munchlax and Dawn's Mamoswine.
- Emolga has developed some sort of rivalry with Ash's Snivy due to the fact that Snivy can see through her supposed cute and innocent act.
- Emolga has developed a friendship with Axew.
- Ash's Oshawott has a crush on her.
- Emolga is the forth Electric-type caught by a character besides Ash. The first character who caught an Electric-type besides Ash was Dawn when she captured her Pachirisu. Cilan comes third with his Stunfisk.
- Emolga is also the first Pokémon in the entire Best Wishes series to retain her original Japanese voice actor. Mika Kanai who voices Ash's Bayleef in both versions of the anime provides Emolga's voice in the Japanese version and now the English-language version as well.
- It can be assumed that apples are Emolga's favorite food.


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Driver version is 9.3.
I have a Dell D610 with an X300 mobile GPU. I also run Ubuntu 9.10 Alpha 2 and it now has a black screen instead of a login screen. Is there a way to fix this. Any help would be great.
Driver version is 9.3.
Uninstall fglrx. The install instructions include a section on uninstall. You won't be able to make the 9.3 driver work on Ubuntu 9.10 without downgrading some major components. Go with the open source drivers which should get installed automatically.
Whats the name of the FGLRX driver? I forgot the name of it. I have the laptop on so I can remove it.
Got a live disc to figure out the name of the driver.


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As in 2014, the KTM Enduro Factory Racing Team continues to field one rider in the E2 class for the 2015 season when Antoine Meo returns to racing after a hand injury in Finland cut short his 2014 season. Meo will ride the KTM 350 EXC-F.
E2 has proved to be the most competitive of the senior enduro disciplines in recent seasons and Meo, a multiple E1 champion with a near impeccable racing record will be chasing down the title for the Orange team. The French rider is a highly respected racer and now that he has returned to fitness, should be a contender for the coming E2 season.
Antoine Meo
Nation: France
Geburtstag: 29.08.1984
Ziele: To win the World Championships
Head of Motorsport | Pit Beirer |
Technical Manager | Florian Ebner |
Race Engines | Markus Dobler |
Technical Director | Stefan Huber |
Racing Development | Gerald Wever |
Chassis Development | Michael Achleitner |
Parts Coordinator | Felix Wagner |
Team Coordinator | Alex Doringer |
Motorsport Identity / PR | Juergen Weisz |
Team Manager | Fabio Farioli |
Suspension | Giel Verspaandonk |
Mechanic Supervisor | Alberto Cattaneo |
Spare Parts | Filippo Ganiomego |
Logistic Manager | Martina Necchi |
Time Keeping | Fausto Casati, Ivano Agliardi, Martina Necchi |
Truck Driver | Paolo Villa |
Catering Chef | Sergio Gentili |
Mechanic Meo | Francesco Vardanega |
Supported Team | |
Mechanics | Cristian Ruggeri, Daniele Bernini, Carlo Valenti |


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Redeem when you want, for what you want.
Reward Nights When redeeming points for a Reward Night, you may only book one room at a time. Once you complete your Reward Night reservation you will be given the option to duplicate this reservation
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** Best Available Rate Search does not include affiliation rates.
To book more than 9 rooms for one stay or request a quote, please use our Easy Meetings tool, call 1-800-MEETING (in United States, Mexico and Canada) or contact a Global Sales Office.
Housed in an historic 19th Century building located in Britain's royal and political heartland, with Buckingham Palace, St. James's Park, Big Ben, the Houses of Parliament and Westminster Abbey in the surrounding vicinity as well as excellent transport links at the doorstep, the Holiday Inn Express London - Victoria is the ideal choice for smart business and leisure traveller.
Enjoy a warm welcome from our friendly multi-lingual staff at our intimate 52 room hotel, in a beautifully restored View More
Enjoy a warm welcome from our friendly multi-lingual staff at our intimate 52 room hotel, in a beautifully restored Victorian building in the centre of London. Excellent transport links mean you can be in any corner of London within minutes as the Holiday Inn Express London – Victoria is a short walk from Victoria & Pimlico underground stations with excellent bus routes on the doorstep!
Victoria provides an immediate link to London's public transport network, Gatwick and Heathrow airports and some of the city's most popular points of interest. For those looking for a fantastic shopping experience, walk to Harrods or the famous Oxford and Bond Street from this central London hotel.
Complimentary Wi-Fi is available throughout the hotel so you can always stay connected! Our free hot breakfast and our cosy, comfortable rooms ensure your stay with us will feel like a home away from home. At the end of the day, unwind at our Beverley Bar which has a wide selection of drinks and snacks. Our knowledgeable staff can recommend some excellent local restaurants.


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Gifted humans
this wiki
Throughout the Twilight series, gifted humans are humans who manifest special abilities, qualities, personality traits or strong desires before they are turned into vampires. After they are turned, that ability or desire will likely magnify into a supernatural talent. Depending on the clarity of its human manifestation, the level of that talent varies after the change.
The Quileute tribal members descended from Taha Aki manifested magical powers that allowed them to transform into giant wolves, though these powers only activate for the fitting age and after coming across a vampire. This and the telepathic link between them in wolf form identifies them as "gifted".
[show]Notable gifted humans
Such humans have made numerous appearances.
- Bella Swan is capable of shielding her mind from all sorts of psychic powers. As a vampire, she becomes able to extend her shield to protect someone other than herself. Her power was seemingly inherited from her father.
- Charlie Swan manifests a mental defense that reduces the effects of a psychic influence on his mind. This trait was later passed down to his much more powerful daughter Bella. Though he is gifted, he does not become a vampire.
- Edward Cullen had been able to read people very accurately as a human. As a vampire, this characteristic evolved into a supernatural ability to read other people's minds, both human and vampire.
- Alice Cullen was gifted with a weak but predictable sense of the future. Her predictions weren't always certain and mostly manifested as feelings, but at times she could see them in visions when the future was set. This ability brought to her names and bad reputation as a human. She discovered her father had hired hitmen to kill her mother and later Alice herself through these visions, but was later taken into a mental asylum, where she befriended a vampire. When Alice witnessed her death at the hands of another vampire named James, her friend turned her to save her. After becoming a vampire, her visions were heightened and allowed her to see the future much more clearly, though it still had flaws.
- Jasper Hale was very charismatic as a human and he was able to persuade others to think his way. After Maria changed him, his charismatic nature became a supernatural talent that allowed him to feel and influence the feelings of those around him. He mainly used it to keep the wild newborns in the army under control. Whenever he killed someone, human or vampire, he felt their pain.
- Jane, and her twin brother Alec, manifested unclear psychic powers to the people around them while they were children. They were able to bring fortune to those who treated them nicely and misfortune to those who treated them otherwise. Aro was told of the twins' latent potential and hoped to change them when they were older. He was forced to change them sooner than expected, when their village accused them of witchcraft and condemned them to burn at the stake. By experiencing the torment of burning death, Jane's anger and desire for others to feel the same pain manifested into an illusionary ability to inflict a burning torment on anyone she saw. After becoming a vampire, Jane's frightening power made her one of the most valuable members of the Volturi guard.
- Alec, along with his twin sister Jane, manifested unclear psychic powers when they were children. Anyone who treated him and his family with kindness was often rewarded with fortune while misfortune was brought on those who did the opposite. Aro was told of the twins' latent potential and hoped to change them when they were older. He was forced to change them sooner than expected, when their village accused them of witchcraft and condemned them to burn at the stake. By experiencing the burning pain that nearly killed him, Alec focused fully on escaping the pain and consequently manifested into a power to block senses. After he became a vampire, his paralyzing power made him one of the most valuable members of the Volturi guard.
- James was a skilled and powerful hunter as a human - he was trained to hunt and trap by his father. This skill allowed him to survive by himself when his parents were killed, and later earned him title and fame in the nearby areas. After he was transformed by a French vampire, this skill manifested a powerful sensory that allowed him to detect his prey's movements and track them down.
- Victoria led an abusive human life: her employers often assaulted her for any fault or just by being visible. To survive, she learned to sneak and hide from her pursuers, and then survive on her own by stealing food without notice and sleeping in the smallest of corners. After she became a vampire, this surviving skill was turned into a power that allowed her to sense and evade danger. Unlike most gifted vampires, her power wasn't withborn. Rather, her abusive human life had perfected her ability to survive.
- Didyme, Marcus's deceased wife, had as a human the dormant ability to induce happiness in others, which prompted her with many suitors. After she changed, it manifested much more strongly. Whoever was with her was always influenced by her happy aura.
- Kate was trained to be a bodyguard loyal to whomever she is assigned to protect. As a vampire, her protective instinct allowed her to cause a shock-like jolt in anyone she touches.
- Benjamin was known to have been an extraordinarily gifted human since he was a child, due to his power to control the natural elements. His distant uncle used his gift for street performance, which prompted Amun to change him. As a human, he only controlled fire, but he began to manifest the other elements after becoming a vampire.
- Maggie was born with the ability to sense whether someone was lying. Anyone who tried to tell lies, Maggie pointed them out, which made her a freak to the townsfolk. By becoming a vampire, her gift manifested much more sharply: it allows her to sense others' lies simply by movements and facial expressions that do not come from his or her true intentions.
- Alistair was a skilled hunter as a human and enjoyed the company of falcons more than people. By becoming a vampire, his skill turned into a power to feel an elusive gravitational pull to whatever he seeks, even inanimate objects.
- Fred shunned all social interactions and became emotionally and physically distant from people. As a vampire, his withdrawal turned into a power that allowed him to drive away pursuers by inflicting them with a sense of repulsion.
- Raoul was a gang leader and a criminal as a human. When he became a vampire, his sense of superiority became a power to draw directionless individuals toward him and make them view him as their leader.
Quileute tribe members
- Kaheleha was a spirit chief of the tribe in ancient times, before the tribe's magic was altered to transforming into giant wolves. At that time, he and the other chiefs possessed the power of astral projection, which they used to protect their tribe from enemies.
- Taha Aki was a spirit chief in the 12th century. He was the first tribal member to shapeshift into a wolf. While astral projecting, his spirit warrior Utlapa possessed his body and impersonated him to take over the Quileute tribe. Unable to use Utlapa's destroyed body, he inhabited the body of a wolf, and later turned into a half-man half-wolf creature to kill Utlapa, becoming the first shape-shifter. He continued to live for two centuries.
- Taha Wi was Taha Aki's son, who naturally inherited the power to phase into a wolf.
- Utlapa was Taha Aki's spirit warrior before betraying him by possessing his body to take over the tribe. At that time, his tribal power was astral projection.
- Yaha Uta was Taha Aki's son who inherited the power to phase into a wolf.
- Yut was Taha Aki's spirit warrior with the power of astral projection.
- Ephraim Black was an Alpha of the wolf pack in the 1930s. As the Alpha, he had control over his followers.
- Levi Uley was the "Beta" of Ephraim Black's pack in the 1930s.
- Quil Ateara II was the third member of Ephraim Black's pack in the 1930s.
- Sam Uley was the first person of the latest generation to inherit the power to shapeshift. As he took care of the other members, he naturally assumed the role of Alpha in the Uley pack, which became important when Jacob refused the role.
- Jared Cameron was the second Quileute of the latest generation to phase, after Sam Uley. He was known to have the best sight of the pack, and was later promoted to his pack's "Beta".
- Paul Lahote was the third person to join the Uley pack. He had the hardest time controlling his phasing, since it was mainly triggered by anger. Furthermore, Paul's temperamental behavior was heightened by the change.
- Embry Call was the fourth Quileute to phase and join the Uley pack.
- Jacob Black was the fifth Quileute to join the Uley pack; with his rightful place to Alpha, Jacob broke away from the pack and formed one of his own. As the Alpha, he had a supernatural command over his followers.
- Quil Ateara V was the sixth person to join the Uley pack, later joining the Black pack to be with his friends.
- Leah Clearwater was the seventh Quileute (and the first female in history) to join the Uley pack, later becoming "Beta" of the Black pack. Despite being the smallest in size, she was known as the fastest in both packs.
- Seth Clearwater was the eighth Quileute to join the Uley pack, and later disbanded to join the Black pack. He was known to have the best sense of hearing in both packs.
- Brady Fuller and Collin Littlesea were among a number of the youngest Quileute to join the Uley pack.
It is questionable whether or not Edward's birth mother, Elizabeth Masen, was gifted. This is supported by her conversation with Carlisle, when she told him to do what everyone else could not do to save her son; in addition, it has been noted that certain gifts are hereditary, similar to Bella and Charlie.


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I don't understand, what is going on. Have AMD given their power to another company in turn for cash?
Phoronix: AMD Splits, Launches The Foundry Company
Since Advanced Micro Devices acquired ATI Technologies back in 2006 they have experienced some financial hardship over this $5 billion USD purchase. In hopes of turning around this situation, AMD has announced this morning they have split themselves from their manufacturing facilities as part of their Asset Smart strategy. AMD combined with Advanced Technology Investment Company, an investment firm from Abu Dhabi, supplying the capital they have formed The Foundry Company...
I don't understand, what is going on. Have AMD given their power to another company in turn for cash?
It's either their power or their biggest burden, depending upon who you talk with.
After reading Wikipedia it all makes sense
So I guess we can experence that it will more profitable to produce Intel CPU's than they own =)IC production facilities are expensive to build and maintain. Unless
they can be kept at nearly full utilization, they will become a drain on
the finances of the company that owns them. The foundry model uses two
methods to avoid these costs: Fabless companies avoid costs by not
owning such facilities. Merchant foundries, on the other hand, find work
from the worldwide pool of fabless companies, and by careful scheduling,
pricing, and contracting keep their plants at full utilization.
That being said, I will never by an Intel CPU/GPU as long as AMD is around.
AMD is doing so much good for open source, so I will support them to the end.
and Intel is one of open source's enemies?AMD is doing so much good for open source, so I will support them to the end.
Sorry, I'm an AMD fan, too. But sometimes, they make it real damn hard to keep loving them.
Look guys, they just basically took the weight of the world off their shoulders... I remember from the very start Intel was invested in hardcore... AMD has been a little rough in that area, it's amazing they've come this far... Sure I have a fully AMD rig right now and I'm really feeling sorry for myself, but there was already hope...
I think now they're going to have much more of an opportunity to interact with us. They're not making hardware anymore, they're designing and implementing it.
How about we all head on over to the AMD website, and instead of crying about our problems, we congratulate them and welcome them with detailed reports of where the software is going wrong, or where the hardware needs improvement. I've been over there a little bit trying to get the Stream SDK up and running and pushing for the stupid little things (4870x2/Crossfire support in a sensible manner). They listen... Maybe they need to be a bit more interactive about their discussions but there's only so much you can hope for, especially when the industry requires them to keep a veil of secrecy over anything that isn't already on the market.
I hate to say it, but if everyone just got together and worked together on this one... Oh but we the people of Ameridumb are capitalists! What ever happened to the Open-Hardware community?
Why isn't there a "foundry" company making hardware designed by the community... Or is there? :P
Alive and kicking, if somewhat attenuated in some corners by lawsuit threats, NDAs, and lack of interest. See e.g. http://www.opencores.org and more generally http://www.opencollector.org
Because it's expensive to start manufacturing a chip design (reportedly it can easily get into the millions of USD in startup costs for a modern process). Some of these "community" designs (more commonly open designs by generous companies) do get manufactured, but not necessarily sold on the open market. I'm pretty sure OpenRISC falls into this category. I don't think there's some great conspiracy against open designs, it's just that the facts of the industry are somewhat hostile to hobbyist efforts because everything is optimized for high-volume production.Why isn't there a "foundry" company making hardware designed by the community... Or is there? :P
I guess I more am thinking some multimillionaire fanatic should step up to the plate . That's how ubuntu came about right? And hey, if you donate right now, you can get yourself a 4870 X2 equivalent video card, fully supported in linux with 0 bugs in wine on ANY supported game!!!!!
Okay sorry I'm dreaming...
Now go look at this pretty picture of the new, New York, facility...
Oh, anyone else seeing that nice glitch near the round front part? I hope this doesn't all mean hardware AND software imperfections!


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Next time you have a gathering of friends over, save the bottles. Using glass paint, you can transform them into whimsical decorations. After they dry, apply a label and beads using a glue gun.
The purple bottle is a standard paint finish, with a bronze color dabbed onto the grooves and ridges.
The metallic version involves one layer of applied paint (thickly by sponging it on) with distress added by randomly rubbing off sections using a Brillo pad. The inside is painted full silver achieved by pouring the paint in, and flipping the bottle upside down to drain the excess. Using a square sponge, I painted the bottom for extra effect.
Included at the bottom of this article are links to the labels I designed using Photoshop. Feel free to use them in your bottle creations.
Have an enchanted day:)


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Bahamas let loose last night..Fun on the Treasure coast.
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Bahamas let loose last night..Fun on the Treasure coast.
Surf in NE Florida has been fairly clean with side offshore winds in the morning and few storms rolling in the afternoon. Nothing big and challenging, but I did get my bum full of sand and my pride stained a bit today. Today (9/8/12) Saw some guys pull into some head high barrels. I had an awesome left which peaked and bowled like a interstate ramp. However, I was like a kid about to laid by the hottest girl in school - Early Release. An just tanked it. guys in the line up gave me the KOOK look. I took off late where the wave sucked up mad, I Slap the board on the trough made the first peril of the board but not the second. That wave will haunt me tonight. I will be out tomorrow sore as all get out, but I will be out like the rest of us.
Send photos.....
va beach has not been that good , Pretty much walled up close outs with a ton of rip . You can catch the occasional shoulder but most of the sets were just closing out. We have surf its just not that ripable
How long could the drive possibly take.. I took this pic friday around noon somewhere on hatteras island.
Attachment 5668
Wed & Thursday (9/5 & 6) were all time in NJ. I was only in town for a week, and left early friday morning. Bummed to leave the middle of the swell, but as soon as i got back to SD my buddy took me to a reef and we scored perfect waist/chest high lefts :D Hopefully you guys get waves for a while from this!!!
Attachment 5669
This what i surfed
I had a great week of surfing. But I remember last year at this time being a little bit better post hurricane Irene. I'm still new at this and I had a blast riding some of my biggest waves yet! Of course, others were catching bigger waves than I, and yes, they were clean ones as well.
Scobeyville... Irene was about as good as it gets around here. It was absolutely ON for that one day, that we'll all remember for our lifetimes.
But sitting here, exhausted... stinging, bloodshot eyes... rashed up and sea lice bitten... sunburned face... totally surfed out... I couldn't bee happier.


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Miguel Cabrera, Fathead
- Overview
Our life-size wall graphics bring major league energy to your fan space. Award-winning third baseman, Miguel Cabrera, takes aim in this hi-def action shot.
- 3' 3" wide x 7' 1" high
- Made of vinyl.
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- Self-adhesive backing removes without any surface damage.
- Dimensions + Care
- Prior to applying your decal, make sure the surface is smooth, free of dust or dirt, and completely dry.
- Decal is not recommended for use on "orange peel" walls or other heavily textured or overly porous surfaces.
- Clean the surface using a soft sponge and lukewarm water with mild soap or detergent.
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- This item ships directly from our manufacturer. Please allow 2-3 weeks for delivery. This also applies to monogrammed and gift-wrapped items.


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Our hotel's location, just minutes from Memphis International Airport (MEM) and attractions in Memphis, makes us one of the top choices when it comes to staying in Olive Branch, MS. The hotel's practical design and comfortable setting allow guests to relax and enjoy their stay for business or a vacation.
Corporate travelers staying at the Holiday Inn Express® Olive Branch hotel can take comfort in the fact that we're only a few View More
Corporate travelers staying at the Holiday Inn Express® Olive Branch hotel can take comfort in the fact that we're only a few miles from the Metro Industrial Park. Our hotel is recognized for the great amenities, including a Business Center and complimentary high-speed, wireless Internet access throughout the hotel.
From visiting the home of "The King" at Graceland to playing a few rounds of golf at the Plantation and Wedgewood Golf Courses, there's plenty to do around Olive Branch, MS. Our hotel's address is very convenient to Snowden Grove and Mike Rose sporting facilities. At night, adults should head over to Beale Street for the great food and live music.
Get a smarter start to your day of touring the Memphis area with our hotel's free Express Start Breakfast Bar. Items like bacon, sausage, scrambled eggs, cheese omelets and our signature cinnamon rolls keep you full all morning long. After your busy day, relax with a good book by our outdoor pool or prepare dinner on the barbecue grill. We even have a Fitness Center so you can keep up with your workout regimen. Book your stay today!


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OutSystems Platform and Force.com: Different PaaS for Different Players
Click here to download now
Overview: This whitepaper, authored by Bloor Research practice leader David Norfolk, compares two different PaaS (platform as a service) solutions - OutSystems Platform and Force.com.
The paper includes a comprehensive analysis of the two PaaS solutions with a focus on providing an objective look at two products that are both "fit for a purpose." The paper provides enough information to help IT professionals determine which product matches their needs and requirements.


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The Rev. James "Seamus" Campbell
3 ReviewsOld Catholic Priest / Alternative Catholic
Maplewood, NJ | 646-325-4445
I am a priest of the Old Catholic Church, Province of the USA, located in Northern New Jersey, willing and able to perform Nuptial Masses or...(more)
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Christina Turner Ward ~ Spirithearts
37 ReviewsPersonalized custom ceremonies for your special day!
Hillsborough, NJ | 908-359-5860
Congratulations! You've made one of the most important decisions of your life and now you are planning the celebration! Your wedding ceremony will...(more)
2014 was definitely another FANTASTIC year for me and I'm looking forward to an even more fantastic 2015! Year after year I have the privilege and...(more)
Dana Silverberg Lawson, Celebrant
42 ReviewsCertified Civil Celebrant - Wedding/Civil Union Officiant
Jersey City, NJ | 609-456-6794
Hi, my name is Dana Silverberg Lawson, Life Cycle Celebrant ® . Creating the wedding celebration of your dreams is my art, my passion. I am a...(more)
Jonathan's review: We live in Texas and were having our wedding on the Jersey Shore. We had to hire a rabbi by telephone and did we luck... (more)
Do you want a wedding ceremony that is unlike those you've seen? Are you hoping your guests will come away feeling that they know you a little bit...(more)
Rev. Michael Savage is an ordained wedding minister/officiant. He conducts non-denominational and interfaith services for couples in Northern NJ, ...(more)
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Ceremony for you By Civil Celebrant Priya Navani
6 ReviewsCreating Memorable & Meaningful Ceremonies for all Occasions
Secaucus, NJ | 201-658-8919
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Rabbi for Interfaith and Jewish Weddings, Bill Kurry
23 ReviewsLove Transcends All Traditions
Little Silver, NJ | 732-245-9965
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Gregg Kits, DD, Wedding Officiant
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Mitch The Minister - New Jersey Wedding Officiant
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NJ Life Events
2 ReviewsYour life events should be acknowledged and celebrated in the manner you choose.....
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Thank you for your service. Active duty military persons desiring a simple ceremony will have all donations/fees waived.
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Revs. Franne and Robert Demetrician
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You've said, "I will!" Now, how will you say, "I do"? With all the style, humor and personality that makes you, well, you! "Congratulations"...(more)
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If you recommend a couple to me and we get to work together, I will rebate 10% of your fee to you! No expiration date! You can even refer people BEFORE your wedding (well, as long as we're working together!)
What a great way to have the officiant you want (oh, that would be me, lol!) at a price that could be, well, zero!
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I offer a 20% discount off my regular wedding fee for couples who are active duty military. Make sure to mention that you are active duty when you contact me!
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Inclusive Ceremonies
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Alisa Tongg, Celebrant
67 ReviewsStoryteller and Celebrant for Aisle-Bound Couples
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Kalorik Dual Zone 18 Bottle Wine Cooler
- $ 248 82 248.82
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Model: OEMWCL20629
Store up to 18 bottles of your best wine under optimum conditions in the Kalorik Dual Zone Thermoelectric Wine Cooler. While your wine enjoys the optimal temperature and humidity conditions within this wine cooler, you get one of the most stylish units available with fully digital temperature controls. This thermoelectric wine cooler features a premium metallic silver finish door trim with double paned tempered glass. The tinted glass door protects your wine from harmful light. The interior of the wine cooler features insulated dual temperature zones with scalloped chrome shelves to cradle and display your wine.
What makes this wine cooler a great choice to preserve your best wine? Its quiet, vibration-free, environmentally-friendly thermoelectric cooling maintains optimum temperature and humidity. It utilizes a state-of-the-art thermoelectric peltier unit to provide vibration-free cooling for your best wines. Vibration from compressor-based cooling systems can disturb the sediments in even the sturdiest of wines. This wine cooler avoids this problem altogether by relying on thermoelectric cooling. The adjustable thermostat means that it can be used to store almost any wine variety under optimum temperature and humidity conditions.
In addition, the peltier cooling unit is silent. The only noise you'll hear is the gentle noise of the fan dissipating heat. Another benefit of thermoelectric cooling is that it uses no Freon, which can be harmful to the planet, and it is so energy efficient it only uses about as much energy as a 75 watt light bulb! Also, the internal fan-forced circulation eliminates "hot spots" within the wine cooler. It features a fan mounted on the back wall to ensure even temperature distribution within each wine cooler zone. There's no need to worry about large temperature differentials or "hot spots" within this wine cooler. Soft interior LED lighting proudly illuminates your wine without creating uneven heat distribution.
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You're the first person in line to enter the arena for Midnight Madness – the start of the college basketball season. From that morning in mid-October through the month of March, you are right there with the team, cheering them on as they go for the National Championship. Show off your team pride with this Team Issued Elite Performance Practice T-shirt by Nike. This shirt is what your Broncos wear for practices. The front features a printed Boise State wordmark with "Basketball" lettering and the Nike Swoosh underneath and the left sleeve displays a school logo. It also has Nike's Dri-FIT technology which wicks away moisture from your skin and keeps you comfortable throughout the day. Work hard, cheer hard and celebrate another big Broncos win as they inch closer to making the Final Four and beyond.
- 60% Cotton/40% Polyester
- Dri-FIT technology for ultimate comfort
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Think of Odyssey as your portal to a world of academic inquiry on the UT Austin campus. There's no better way to come back to campus than by enjoying a class with a renowned UT professor or local scholar. The best news of all? There are no tests or grades. And Odyssey is open to everyone!
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text: 1898: Saucony is founded by four business men on the banks of the Saucony Creek in Kutztown, PA where they produce their first shoes for children. 1910: Abraham Hyde opens a shoe store called A.R. Hyde & Sons. The company manufactures ""carpet slippers"" made from rug remnants which proved to be very popular. 1932: Hyde adds his first sport-specific footwear, ""pleasure skates"", for ice skating. 1938: The athletic line grows to include baseball shoes, roller boots, and bowling shoes. 1942: During World War II, the Hyde Co. creates Army Boots. 1963: The company produces the boots worn by the first American astronaut to walk in space. 1968: After acquiring Saucony Shoe Manufacturing Company, Saucony running shoes become a closely kept secret for 10 years. 1977: Saucony shoes are recognized by a small group of serious runners and receive an award given by a US magazine. The resulting publicity establishes Saucony's name and the ongoing reputation for high quality and innovative technical performance. 1980: Saucony introduces the first slip lasted running shoe, the Trainer 80. 1981: Launch of the Jazz O, the most popular shoe in Saucony history. 1987: First technical walking shoe. 1991: First midsole technology to offer both cushioning and stability. 1993: First molded EVA dual density midsole. As Saucony moves forward and continues to establish itself as a leading technical running company it is also placing a renewed dedication into the retro fashion category that is Originals. Built around the Jazz O, we have a number of authentic running shoes that have been brought back to celebrate our glorious past. From the Courageous to the Trainer 80, they have all played a significant role in Saucony's authentic running history. (read more)


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Boston Celtics Kids Preschool & Toddler
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Your little Boston fan can't wait to attend his first Celtics game. Make sure he's dressed in style for the big day with this Front Whirlwind T-Shirt from adidas. It features kids-style "Celtics" lettering on the front with the team logo. Your young one will be so happy when the Celtics win and he's sporting his cool Celtics tee.
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Finally some good news from the OGL camp. They need to have some good press instead of getting ripped like they did in a recent OGL3 vs DX11 article.
We were expecting a lot from OpenGL opengl 3, and as you can tell by reading this article, we're disappointed—both in the API itself (with the disappearance of promised features) and in the way it's been handled (a year-long delay and a lack of clear communication on the part of the Khronos group). With this version, OpenGL barely keeps up with Direct3D direct3d 10, and at a time when Microsoft has chosen to publicize the first details of version 11 of its own API.
There's nothing revolutionary from Microsoft either, but unlike OpenGL, Direct3D already underwent a major revision of its architecture two years ago. There were some rough stretches of road, but today Microsoft can reap the benefits of the efforts made then to rebuild the API on a sound foundation.
So, it's undeniable that Redmond is looking to the future, whereas one gets the impression that Khronos is content with just supporting current GPUs. Here's hoping it'll prove us wrong by speeding up the evolution of OpenGL 3, since it is the only API available for multi-platform development. But too many letdowns up until now certainly have our faith in the organization shaken.


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Please note - this year's competition is now closed for entries. Welcome to the FW Photography Competition 2011. You can submit a maximum of six entries by uploading them directly into this gallery. All you need to do is click on the 'add picture' option in the 'My Tasks' box on the right hand side of this gallery (you'll need to register with FWi if you haven't already done so, but that is quick and easy). Please say which category you wish your picture to be entered into. We'll be accepting entries from October 21 to November 18, 2011.
1,543 total photos Last updated on Mon, Nov 5 2012


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English Department
"You may never get to touch the Master, but you can tickle his creatures." - Thomas Pynchon, Gravity's Rainbow (1973)
English @ USA
Welcome to the Department of English, one of the largest departments at the University of South Alabama. More than 4500 students attend courses every year offered by our dedicated and diverse faculty. In addition to serving our undergraduate majors, we offer minors in English and professional writing, we administer the University's freshman composition program, and we have a vibrant Master's program with concentrations in literature and creative writing. We also co-host the USA Writer in Residence and we house the Stokes Center for Creative Writing.
Chair's Welcome
From Freshman Writing to advanced graduate work, the Department of English offers students the tools they need to understand and interact with the world around them: reading, writing, and interpretation. A variety of courses in writing, language, and rhetoric develop effective, critical communication and thinking skills. Courses on literary genres, periods, theories, and themes, and on literary criticism, provide opportunities to engage with and in literary traditions and practices and an understanding of the role and value of literature in our own world.