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Fat mouse, skinny mouse Investigating metabolism with genetic engineering For our ancient ancestors, the ability to store fat was critical to survival. They were hunter gatherers whose food supplies were unpre- dictable and could fluctuate widely depend- Mouse metabolism ing on season, drought, competition with animals, and many other factors. Humans evolved the ability to store fat efficiently when food was plentiful so that its energy could be used in leaner times. Our modern lifestyles, however, are frequently at odds with the way BRIEFS our bodies have evolved. Constant access to abundant food and a lack of physical activity means that many of us are consuming and storing much more fat than we are likely to need, and this is having a dramatic effect on These mice were both fed the same high-fat diet. The mouse on the right remains normal-sized despite this our bodies. enriched diet because it does not have the AdPLA gene, while the genetically normal mouse on the left becomes obese. According to the National Institutes of Health, approximately two thirds of adult Americans are overweight. Of those, half are food is not being consumed, levels are low causes fat to be burned in a unique way. In obese. Excess weight puts people at risk for and fat is burned. lipolysis, fat is usually released straight into a myriad of health problems such as heart The enzyme AdPLA, short for adipocyte the blood stream. However, the fat has to disease, type II diabetes, and hypertension. phospholipase A, plays a critical role in li- go somewhere, and what isn't used for en- A 2002 study estimated that approximately polysis. AdPLA is at the beginning of a chain ergy will collect in other places in the body. $92 billion was spent annually on health care of protein interactions that eventually leads "When lipolysis happens [in the absence of costs related to weight problems, or about to the breakdown of fat. AdPLA is inhibitory, AdPLA], fatty acid is not released into the 9.1% of all health care costs. Clearly, under- meaning that it prevents lipolysis. AdPLA is blood," explains Hei Sook Sul, "it mostly standing and controlling weight are critical abundant during feeding, so when an animal burns inside the adipose tissue." Thus, a to improving health and reducing health eats, AdPLA prevents fat from being broken patient taking an anti-AdPLA drug should care costs. Recently, researchers in Hei Sook down and allows for fat storage. not develop complications from excess fat Sul's laboratory from the Nutritional Science Using a process called knockout cloning, circulating and collecting in the body. Sec- Department at UC Berkeley discovered an the lab created a mouse in which the gene for ond, AdPLA is made exclusively in adipose enzyme called AdPLA that plays a critical role AdPLA was removed from the animal's DNA tissue and has only this one known function. in fat metabolism. so the enzyme would no longer be produced. Other molecules involved in fat metabolism The body regulates fat with two oppos- They found that animals with this mutation are found throughout the body and have ing processes: it can either burn it or store it. did not gain weight, even when fed a high-fat multiple functions. For example, insulin is When a person consumes fat, carbohydrates, diet. Graduate student Maryam Ahmadian a hormone produced in the pancreas and or other foods, the molecules are broken further explains, "We found that even when circulated throughout the body. In addition down and transformed into lipoproteins, AdPLA knockout mice have another muta- to its ability to inhibit lipolysis, insulin also centers of fat molecules surrounded by tion that causes extreme overeating and obe- regulates blood glucose and other physiologi- proteins. In this form fat can be circulated sity, these mice still remained slim." Without cal processes. While a drug targeting insulin through the blood stream. Excess fat in the this enzyme present to prevent lipolysis, fat would affect all these processes all over the blood is taken up by fat cells, broken down was constantly being burned, even at times body, essentially mimicking type I diabetes, again and stored in what is called white when the body should have been storing it. a drug targeting AdPLA would only affect adipose tissue. When the body requires more The researchers believe AdPLA could be lipolysis in adipose tissue. energy, the fat in the adipose tissue is broken an ideal drug target. A drug that binds to the The discovery of this gene may also aid down in a process called lipolysis. It is then enzyme could temporarily disable it, thereby scientists in studying how fat metabolism dif- reformed into lipoproteins and released into increasing lipolysis and helping a person lose fers among individuals. Weight is influenced the blood stream. These two processes are in weight. AdPLA has some unique features not only by food intake and activity level, MARYAM AHMADIAN constant balance. When a person eats, levels that the researchers believe may make it a far but also by genetics. Some individuals seem of signaling molecules that prevent lipolysis better target than other known regulators of prone to being heavy, while others seem increase, allowing fat to be stored. When fat metabolism. First, the absence of AdPLA to never gain weight no matter how they 10 behave. By analyzing the genetic variations molecules are attached to the target mol- Now, Foundry researchers have synthe- in AdPLA and other critical fat metabolism ecules the researchers want to study, and then sized a new kind of nanocrystal that does not genes, researchers hope to learn what muta- they show up against the dark background as blink. "Our results show a single nanocrystal tions might put a person at risk for becoming bright spots of colored light that reveal the is stable and bright enough that you can go overweight. location of the targets in the cell. out to lunch, come back, and the intensity Various small organic molecules can be remains constant," said Jim Schuck of the used as fluorescent tags, and another com- Foundry's Imaging and Manipulation Facility, Melanie Prasol is a graduate student in monly employed choice is green fluorescent who led the research team. molecular and cell biology. protein (GFP), whose discovery was the Their new quantum dots are made of Quantum dots subject of the 2008 Nobel Prize in Chem- an inert matrix of sodium yttrium fluoride istry. However, these all have a fatal flaw: if (NaYF4) embedded with ytterbium (Yb) and you leave the UV lamp shining on them for erbium (Er) atoms, dopants from the bottom even a few seconds, the fluorescence dies of the periodic table, where elements have away, a process known as bleaching. This strong fluorescent emission of visible light. BRIEFS susceptibility to bleaching makes it difficult Rather than using UV light, which is higher Quantum dots to track objects over time. A solution came in the form of semiconductor nanocrystals in energy than visible light, these quatum dots are excited by infrared light, which is light up (also known as quantum dots), little bits of inorganic materials whose fluorescence is lower in energy. First, one of the atoms of Yb in the dot absorbs an infrared photon. Seeing inside cells more brighter and more resistant to degradation It then transfers its energy to a neighboring by light. atom of Er, which can then absorb another clearly Nevertheless, there is still an irritating infrared photon, providing enough energy to problem with quantum dots: they blink. finally emit a photon of either green or red The British newspaper The Telegraph once Imagine trying to watch quantum-dot- visible light. This novel infrared-to-visible defined nanotechnology as "the science of labeled proteins moving around a cell, and imaging process led the researchers to term invisibly tiny things." Visualizing invisible having their fluorescence occasionally dis- their creation "up-converting nanoparticles," tiny things can prove quite a challenge, and a appear. Even when they turn on again, you or UCNPs (in a—perhaps unconscious— major research area in nanoscience is indeed can't match them with the proteins you were allusion to their employer). the search for ways to make the "invisibly tracking before to have the full trajectory. The In traditional quantum dots, all of the tiny" visible. Recently, a team of researchers underlying mechanism of blinking is still atoms in the dot participate together in at Lawrence Berkeley National Laboratory's hotly debated; regardless, blinking has been fluorescence, causing the dot to blink on and Molecular Foundry made a new advance a significant limitation for researchers using off as a whole. The crucial difference with in this field that will help in imaging single quantum dots. the UCNPs is that each Yb and Er atom in molecules under the microscope, a subject of great interest to biologists and medical researchers. To understand how cells work, it is very useful to be able to visualize the locations of molecules within a cell and track their move- ments in real time. However, cells are mostly transparent and it's not easy to distinguish their components under a microscope. The centuries-old method biologists have used is to apply stains that bind to the structures within a cell and make them different colors. More recently, they have turned to fluorescent tags that greatly increase the contrast and al- low targeting of particular molecules. In the fluorescence process, light of a specific wave- length is absorbed, "exciting" the molecule, and is re-emitted as lower-energy light as the molecule relaxes. Usually, ultraviolet (UV) 100 nm light from a mercury lamp in a microscope ANDRE GEIM is used to excite the tag because it results in Quantum dots can be made of a variety of materials. A quantum dot carved out of a graphene sheet is shown emitted light in the visible range. Fluorescent above. 11
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What Not to Wear 2003 | TV Show Watchlist
Photos | Cast & Crew | Episode Guide | Video Clips
The U.S. version of the BBC makeover series has style experts picking apart---then attempting to fix---the fashion and grooming faux pas of generally schlubby participants, who were nominated by friends and family. BBC America carries the original BBC vers (more…)
Premiered: March 8, 2003
Rating: TV-PG
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Lizz is a stage mom of nine who has put her family's needs over her confused style of short skirts, thrown together layers and boots. Can Stacy and Clinton get this busy mom to drop her inappropriate sexy style and finally discover an identity of her own?
Skimpy dresser, Riana wears clothes that are too tight. Megan's frumpy wardrobe doesn't work for her body, and Taylor's boho style is just too mismatched. In this episode, Stacy & Clinton take on all three friends to help each find their own unique style.
Katherine has always dressed differently than everyone else so she wouldn't look like she was trying to be part of the crowd. Can Stacy and Clinton help transform Katherine's lazy, youthful style into a refined, professional look suited for a new career?
Tristen is from upstate New York, but considers herself a Jersey girl at heart. Will Stacy and Clinton get this Jersey shore wannabe out of her skimpy outfits, and into a wardrobe that will advance her career aspirations and attract a quality man?
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Fertilizing / spraying bugs
Should minis be fertilized throughout the growing season? I have some organic rose food that I purchased and I applied some in the spring. The plants are all blooming beautifully now and I'm not sure what the rules are about fertilizing. I know with clematis, you're not supposed to fertilize while they're in bud/bloom, but not sure about roses.
Also, I sprayed them a couple of weeks ago because they had tiny white bugs on the buds (I've also seen these same bugs on my columbine buds). I suppose they must be aphids. How often should they be sprayed?
Thanks much!
Yes, they are like other roses and need to be fertilized throughout the season. Especially after bloom cycles. I would put down another application of the organic fertilizer after most of the plants have finished blooming this go-round.
No spraying for aphids, it is unnecessary. A squirt with water or dusting with flour or just leaving alone. Too much use of insecticides can lead to a spider mite infestation, and they are much worse than the aphids.
Thanks, Diane. So the aphids aren't bad for the plants? Oops. I'd rather not spray unless necessary, but I saw lots of the little white bugs on the buds and thought they needed to be taken care of. Well, live and learn.
Okay, I will fertilize them when they're done blooming this time.
Thanks a lot!


text: We enjoyed this small hotel just a few blocks from Salzburg's Old Town, concerts and many museums. Vivienne and her staff were very helpful and friendly. This hotel is not fancy, but met all our needs perfectly. Breakfast was complete and very good. We will return the next time we visit Salzburg.


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- New technological breakthrough / Freelance Chair :)
You probably spend more time in front of the computer in order to finish your tasks on time. You end up sitting on the chair for hours which leads to a multitude of problems with your health while also wasting time over obsolete movement. With the "Freelance Chair" those problems are over.
- Legend:
1. 3D Sound, start listening to your favourite music so work becomes pleasure.
2. Leather leaner proven by medicine not to have a negative influence over your health.
3. Operating the chair is realized through a Playstation-like joystick so that you can learn to use it faster
4. Outlet tubes releasing your "dirty angers".
5. Refrigerator with cold beverages and food.
6. Sport tires enduring even the minimized motion of the chair.
7. Adjustable foot leaners fits your height perfectly.
8. Seat - no need to get up and waste important time going to the toilet.
9. Fan (optional) - for those of you who do not posses an AC.
- Let's have fun while working. Enjoy ;)


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Figure Skating
New Non-Profit Plans To Help Kids Out With Sports Fees
A new Twin Cities non-profit aims to help more students get involved in sports, despite any financial obstacles. The InSports Foundation was the brainchild of a college student from Moorhead.
The High Cost Of Competitive Pre-H.S. Sports
Competitive sports are starting earlier and costing more than ever. So, we're taking a look at how much families are really paying to play in some of the most popular sports.
2014 Sochi Games Pregame Playlist
As Team USA gears up for the biggest sporting events of their lives in Sochi, they need some motivation to push themselves in ways they never have before.
Best Places To Go Ice Skating In Minnesota
The state of Minnesota enjoys unlimited opportunities for ice skating. There is a respectable balance of places to go for tuning those skating skills and the Land of 10,000 Lakes has everything going for it in the ice department.
Kristi Yamaguchi Talks Skating And Literacy On WCCO Morning News
Olympic Skating gold medalist and Dancing with the Stars Champ Kristi Yamaguchi called into the WCCO Morning News with Dave Lee on Friday.
Rochester To Host 2012 Star Of The North Games
Rochester will host the 25th anniversary Star of the North Games next year.
Skating Club Hosts Benefit For Edina Fire Victim
A community hit the ice in honor of a Twin Cities woman killed in a fire.


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Real Salt Lake sinks lowly Toronto FC
SANDY, Utah (AP)
Jonny Steele scored in the 93rd minute to give Real Salt Lake a 3-2 victory over Toronto FC on Saturday night, the Canadian club's record-tying seventh straight loss at the start of the season.
See all the action from week eight of the MLS.
Just 10 minutes after entering the game Saturday night, Steele scored a dramatic go-ahead goal to give the host a late win.
''I know that Jonny will want a lot more minutes going forward,'' coach Jason Kreis said. ''If he keeps contributing in that fashion, he'll get more consideration.''
For Steele, he is just relishing the chance to be a difference maker after hopping from one team after another during his first eight seasons of pro soccer. The Northern Ireland midfielder simply wants to be someone his team can count on when he is on the field.
''As long as I can contribute something and as long as I can put some hard work in, if the chances come and I take them, then I'll be happy,'' Steele said.
Steele helped Salt Lake (6-3-1) avoid an embarrassing draw against one of the worst teams in Major League Soccer. Toronto dropped to 0-7, matched the season-opening futility mark set by Kansas City in 1999.
''We just need to keep our heads up,'' Toronto midfielder Julian de Guzman said. ''This is not the time to drop our shoulders. It is not the time to lose our confidence.''
Kyle Beckerman also scored for Salt Lake (6-3-1), which took a 2-1 lead in the 57th minute on Richard Eckersley's own goal. Eric Avila and Doneil Henry scored for Toronto.
''We didn't come out and finish the game and we were punished for it,'' Henry said.
Beckerman opened the scoring in the seventh minute with his third goal of the season.
Javier Morales set the play in motion when he boomed a corner kick to Jamison Olave at the far post. Olave headed the ball back to Chris Schuler at the opposite post. Schuler knocked it down and kicked the ball to Beckerman in front of the goalmouth. The midfielder finished off the pinball play by tapping the ball home.
Toronto had a chance to tie it in the 18th minute after a foul by Olave set up a penalty kick. Torsten Frings took the kick and missed, sending the ball ricocheting off the left post.
Toronto tied it in the 48th minute. Avila juked past Olave and drew Nick Rimando out of the goalmouth. Avila slotted the ball past him and squeezed in inside the right post.
On the own goal in the 57th, Eckersley tried to get to a cross from Fabian Espindola before Alvaro Saborio could reach it. The ball deflected of Eckersley.
Toronto tied it again in the 77th minute. Miguel Aceval served up a corner kick into the center of the box, and Henry sprang up from a crowd of players and headed the ball backward into the corner of the net.
''We were so close to putting this team away,'' Salt Lake midfielder Will Johnson said. ''Then we let them back in twice.''
Steele, who substituted for Ned Grabavoy in the 83rd minute, came up with the winning goal 10 minutes after taking the field. Beckerman lunged for the ball and set Steele up at the top of the box. He sent a shot straight down the area and ripped the ball past goalkeeper Milos Kocic.
''It was a great way to finish the game,'' Beckerman said.Jonny Steele scored in the 93rd minute to give Real Salt Lake a 3-2 victory over Toronto FC on Saturday night, the Canadian club's record-tying seventh straight loss at the start of the season.
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SOCCER Headlines
Klinsmann recalls Shea, Onyewu to USA senior squad
USA-Ukraine friendly moved due to civil unrest in Kiev
McBride, Lilly, Bradley elected to US National Soccer Hall of Fame
USWNT's Morgan to miss Algarve Cup with ankle injury
Hoffenheim's USA midfielder Johnson to sign for Gladbach
Starting over: MLS purchases Chivas USA from Vergara
USA to host China in Colorado after Algarve Cup
Liverpool, Manchester United announce opponents for US tour
Violence puts USA's exhibition against Ukraine in jeopardy
Julio Cesar signs loan deal with Toronto FC | Inside MLS


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My order for Masuda: Two Card Mysteries arrived promptly. Thank you. Easy to learn and perform and fooled the hell out of a crowd of well posted...Read More ->
This is my second order from MJM and I have been very pleased to date. I paid less than $3 shipping this time and received my order very quickly. The...Read More ->


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Expo Milano: Feeding the Planet – Energy for Life
May 1 to October 31, 2015
Milan, Italy
Over 140 participating countries at the Expo will show the best of their technology that offers a concrete answer to a vital need: being able to guarantee healthy, safe and sufficient food for everyone, while respecting the Planet and its equilibrium.
A platform for the exchange of ideas and shared solutions on the theme of food, stimulating each country's creativity and promoting innovation for a sustainable future, Expo 2015 will give everyone the opportunity to find out about, and taste, the world's best dishes, while discovering the best of the agri-food and gastronomic traditions of each of the exhibitor countries.
Dr. Alessandro Galli, Global Footprint Network's Director of Mediterranean and MENA Regions, will speak at the Expo on May, 23rd, 24th, and 25th on his intervention entitled Mediterranean Footprints & Foodprints: Who should go on a diet? A set of questions: How much nature does humanity use and how much can our planet regenerate?
The Ecological Footprint is a widely used data-driven metric that answers these questions and helps tell us how close we are to the goal of sustainable living. Food is a basic need, so how does the food sector contribute to the overall demand that Mediterranean countries place on our planet's natural resources? Attend this session to learn more about the Ecological Footprint and how it informs food resource access and utilization in Mediterranean countries.
Additional information on Dr. Galli's presentations (German).
Register for a session with a link below (website available in English, German and Italian). May 23rd | May 24th | May 25th


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Settlement on the site commenced in about 1838. Present-day Mugga Mugga is set on seventeen hectares of grazing land, its centerpiece is a simple cottage built for the head shepherd of Duntroon in the 1870s.
OPEN HOUSE: Senior citizens
Sun 15 March: 1.30–4.30pm
Join a guided tour introducing the story of the Curley family cottage and pioneer rural workers of the Limestone Plains, followed by a self-serve afternoon tea in the Education Centre. In association with ACT Seniors' Week.
Free for senior citizens; otherwise normal admission. Please book for large groups.
HERITAGE FESTIVAL EVENT: National Trust Open Day
Sun 12 April: 10am–3pm
Discover Mugga-Mugga, a shepherd's cottage once part of Duntroon Estate, at the Heritage Festival Open Day. Come along and see this reminder of Canberra's rural past and gain an insight into the housing and way of life of nineteenth and early twentieth century rural workers. You can tour the cottage and learn about its history and that of its occupants, including the Curley family who lived there from 1913 to 1995. You can also take part in various fun activities, enjoy live entertainment and refreshments. In partnership with the National Trust of Australia (ACT), with support from ACT Heritage.
Gold coin donation, enquiries via the National Trust on 6230 0533
OPEN HOUSE: Mother's Day
Sun 10 May: 1.30–4.30pm
Visit Mugga-Mugga cottage this Mother's Day and gain an insight into the lives of the rural workers who worked the Limestone Plains. Following a tour of the cottage, a self-serve afternoon tea will be provided in the Education Centre.
Free entry for mothers and grandmothers, otherwise normal admission.
SYLVIA CURLEY ORATION: Professor Zsuzsoka Kecskes
Sun 24 May: 2–4pm
A driving force of innovation and a willingness to push gendered boundaries, Professor Zsuzsoka Kecskes, Neonatal specialist and ACT Australian of the Year 2014, is best known for her inspiring and award-winning work with babies and families in the Neonatal Intensive Care Unit at the Centenary Hospital for Women and Children. Professor Kecskes will discuss the revolutionary shifts that are occurring in hospital practice today, and reflect on her highly accomplished work and research which continues to inform best-practice treatment of newborn babies in Australia and around the world. A lecture to honour Sylvia Curley's dedication to innovation and improvement in the medical profession.
Free, RSVP by Wed 20 May.
Copyright © 2001-2008. ACT Museums and Galleries


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Eureka vs. Lisbon lemon
Which do you prefer and why? Is one cold hardier or more robust than the other? Tree thorniness? Any other difference you note. Thanks.
Okay, I am prejudiced; if I have to choose between Eureka or Lisbon I would choose Meyer!!... For California the Lisbon is better for fruit size mostly; and it has a little more esthetic shape. For New Jersey, I would go with Eureka, it stands cold a little better. FYI the 3 main varieties of "Lemon", which in English means yellow, are Eureka, Lisbon, and Berna (I call them the ELB base, as they are fungible; i.e., the consumer cannot or does not differentiate among them. You can add the Villafranca from Italy and the Genova from Chile, lesser varieties that fit the same mold... they all look similar and sell for the same price. The Meyer, being a superior lemon in every way, typically sells at 2-3 times the ELB base; but is a bit more sensitive in post harvest handling, shipping and shelflife.
The Eureka is at home in the cool Pacific Coast climate. I have read where Lisbons do well in near desert climates in California. I have seen a few very high quality Lisbons grown in warm micro climates in Houston. In my experience and along with some long time citrus growers, it is a waste of time trying to grow Eureka in the heat of the Gulf Coast or similar climate.
Now for the subjective part. I find the aftertaste of Meyer to be objectionable if used as fresh juice. A dessert chef can do wonders with it. That's not just me, I know of others who think the same. I also know plenty of people who like the taste of fresh Meyer lemons.
In Texas, Meyer lemons from the Rio Grande Valley are marketed as "Valley lemons" and may be priced from 2/3 of the true lemon price to little over true lemons.
For me, the Ponderosa can't be beat for lemonade.
I just bought myself a Lisbon, to go with my Meyer and my Pink Lemonade (Eureka). I have read that they have a slightly cleaner lemon flavor than the Eureka. They are supposed to be thornier than Eureka, but also more cold tolerant once well established.
Reading mixed info on cold tolerances of each. Have had great luck with the Meyer's and Eureka. We'll see, just bought myself the Lisbon..--Heck, if you're a citrus freak might as well go all out, right. My Meyer's is quite compact (due to it being a dwarf), the Eureka is sprawling--productive but not kind of gawky, would you say the Lisbon is more compact/denser?


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Short Cuts
The otherwise unknown patron saint of a church and well in Ciwyd, Wales.
St. Matthew
Maximilian was born in 1894 in Poland and became a Franciscan. He contracted tuberculosis and, though he recovered, he remained frail all his life. Before his ordination as a priest, ... continue reading | shop
She is called "the Penitent". St. Mary was given the name 'Magdalen' because, though a Jewish girl, she lived in a Gentile town called Magdale, in northern Galilee, and her ... continue reading | shop
Pictures of St. George usually show him killing a dragon to rescue a beautiful lady. The dragon stands for wickedness. The lady stands for God's holy truth. St. George was a brave martyr ... continue reading | shop
St. Benjamin, Martyr (Feast Day - March 31) The Christians in Persia had enjoyed twelve years of peace during the reign of Isdegerd, son of Sapor III, when in 420 it was disturbed by the indiscreet ... continue readingMore Saint of the Day
Brigid was probably born at Faughart near Dundalk, Louth, Ireland. Her parents were baptized by St. Patrick, with whom she developed a close friendship. According to legend, her father was Dubhthach, an Irish chieftain of Lienster, and her mother, Brocca, was a slave ... continue readingMore Female Saints
St. Michael the Archangel - Feast day - September 29th The name Michael signifies "Who is like to God?" and was the warcry of the good angels in the battle fought in heaven against satan and his followers. Holy Scripture describes St. Michael as "one of the chief ... continue reading
The name Gabriel means "man of God," or "God has shown himself mighty." It appears first in the prophesies of Daniel in the Old Testament. The angel announced to Daniel the prophecy of the seventy weeks. His name also occurs in the apocryphal book of Henoch. He was the ... continue reading
Francis was a young nobleman at the court of the King of Spain. He became a Duke when he was only thirty-three and lived a happy, peaceful life with his wife Eleanor and their eight children. But ... continue reading
Artaldus (also called Arthaud) was born in the castle of Sothonod in Savoy. At the age of eighteen, he went to the court of Duke Amadeus III, but a year or two after, he became a Carthusian at ... continue reading
By Alex Basile
Every carpenter must practice patience. We can learn important lessons from the wood shop in Nazareth from the humble Saint Joseph. I have always been a "do it yourself" type of guy thanks to my father. My dad is always a steady presence during my home-improvement ... continue readingMore Christian Saints & Heroes


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January 13 is indeed a remarkable date to remember. The event called "Global No Pants Subway Rides 2013" occurred in several cities worldwide as participants from New York City to Amsterdam strip off their pants and have a good time with semi-nudity while traveling.
Improv Everywhere commenced in 2002 the "No Pants Subway Ride" in New York City. On Sunday, the controversial annual event took place on its 12th year already. Proof that it continues to grow strong, more than 4,000 commuters gathered at several meeting points in New York City during the 52-degree weather.
The said event occurred as well in 60 cities in more than 25 countries worldwide. In Australia, the social networking site "Facebook" posted information on the events for the interested participants in Adelaide.
The page reads: "It's time again for the 6th annual No Pants Tram Ride in Adelaide. The basic idea is to ride the tram without pants and pretend that it is the most normal thing to do. When people see one person doing this they can easily pass them off as a crazy, but when more and more people enter the tram without pants, apparently unknown to each other, the reactions are just priceless. This event is always great fun and with the hot weather, it's often more comfortable than wearing pants anyway."
Other Australian cities noted on Facebook's "Global No Pants Subway Rides 2013" page are Brisbane, Sydney and Melbourne. Organizers are obviously pleased and grateful to the participants with the outcome of their campaign.
Improv Everywhere wrote on their official web site improveverywhere.com: "You can be a part of the global activity by tweeting with the official hashtag #NPSR and @ImprovEvery when talking about Improv Everywhere. Be sure to sign up for our mailing list so you'll stay updated on future events like this. You can also like us on Facebook, follow us on Twitter and subscribe to our YouTube channel.
Previous "No Pants Subway Rides" videos and photographs in Adelaide can still be viewed at the link: http://www.adelaideflashmob.com/no-pants/


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Job Posting: 1Job Title: Registered Dietitian (RD)/ WIC Nutrition Coordinator Local Agency: 36 Contact/E-mail: Nevin CunninghamCity: San MarcosPhone: (512) 393-8060
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How to Apply: A City of San Marcos on-line application is required. Visit https://jobs.sanmarcostx.gov and select 'Search Postings' to apply and/or to obtain the complete job description. You may attach a copy of your resume/cover letter at time of application. You should receive an online confirmation once you have successfully submitted your application.
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Job Posting: 2Job Title: Breastfeeding Peer Counselor SeniorLocal Agency: 001Contact/E-mail: Donna SundstromCity: Austin Phone: 512-972-6844
How to Apply: Apply online at www.austincityjobs.org. The position will be posted under Health and Human Services Department.
Salary: $15.10-$18.79 hourly
Job Posting: 3Job Title: WIC Clerk/Health AideLocal Agency: 29-10Contact/E-mail: Sheila LentiniCity: StaffordPhone: 281-633-3198
Job Description: Perform assigned clinical, technical and clerical support necessary to complete the WIC certification process and issuance of WIC food vouchers.
How to Apply: Go to www.myaccesshealth.org to complete an application.
Salary: Based on experience
Job Posting: 4Job Title: WIC Clerk/Peer CounselorLocal Agency: 29-10Contact/E-mail: Sheila LentiniCity: Prairie ViewPhone: 281-633-3198
Job Description: Perform assigned clinical and clerical duties necessary to complete the WIC certification process. Offer pregnant and lactating women support, encouragement and information needed for a successful breastfeeding experience.
How to Apply: Email resume to email@example.com
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Job Description: Under direct supervision of WIC Assistant Director, acts as a WIC Clinic Supervisor, including direct supervision of Nutritionists, LVN's, WIC Community Service Aides(CSA), WIC Certification Specialists(WCS)and/or Breastfeeding Peer Counselors(BFPC). Determines WIC eligibility, performs nutrition assessments and counseling, nutrition education classes. Provides breastfeeding support and issues breast pumps. Approves non-contract infant formulas. Other Duties performed as assigned.
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Overview of content related to 'data set'
This page provides an overview of 1 article related to 'data set'. Note that filters may be applied to display a sub-set of articles in this category (see FAQs on filtering for usage tips). Select this link to remove all filters.
A data set (or dataset) is a collection of data, usually presented in tabular form. Each column represents a particular variable. Each row corresponds to a given member of the data set in question. Its values for each of the variables, such as height and weight of an object or values of random numbers. Each value is known as a datum. The data set may comprise data for one or more members, corresponding to the number of rows. (Excerpt from Wikipedia article: Data set)
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Cultural Heritage Language Technologies: Building an Infrastructure for Collaborative Digital Libraries in the Humanities
Jeffrey Rydberg-Cox describes the work of the Cultural Heritage Language Technologies consortium, a research group funded by the European Comission Information Society Technologies program and the United States National Science Foundation Digital Libraries Initiative.
January 2003, issue34, feature article


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No place blends basketball and politics quite like Georgetown. Who among the student body hasn't paused his or her episode of the West Wing in order to head to the Verizon Center? One question, therefore, dominates the thoughts and conversations of everyone on campus: Which former president would Head Coach John Thompson III have recruited?
As it turns out, JTIII has two top targets. Our experts are on the scene to share their scouting reports.
Honorable Mention : John F. Kennedy — 6'0" G
Molly O'Connell: Simply put, he has the right personality for this team. Much like the Hoyas, JFK was generally well liked, but horrifyingly inconsistent. The way he handled the Cuban Missile Crisis was pretty awesome, kind of like absolutely destroying No. 4 Villanova. Rumor has it the White House staff stormed the situation room after the Soviets folded. The Bay of Pigs on the other hand reminds me of losing to Villanova by 16 three weeks after beating them by 20.
Woodrow Wilson — 5'11" G
Russell Guertin: Wilson, the 13th President of Princeton, would quickly mesh into the Princeton offense. Plus, Thompson always loves supporting his alma mater.
Dillon Mullan: Wilson, like JTIII, has strong ties to Princeton. He already knows the offense.
William Howard Taft — 5'11" C
Maddie Auerbach: Considering that Thompson loves having big senior center Josh Smith on the court, I don't see why he also wouldn't favor another 300-pounder. Though Taft's 5'11" stature doesn't compare to Smith's 6'10" height, Taft would dominate the paint in a similar way that we've seen Smith do all season long. As long as Taft doesn't commit 3-second violations as frequently as he gets stuck in bathtubs, I think that JTIII would instantly pick up our most obese president in a throwback draft.
Tyler Park: Thompson would have recruited William Howard Taft. It's clear from his use of Josh Smith that Coach knows how to use a massive big man on the block. Taft might be limited to only about 11 minutes per game, but he would be a force under the basket.


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Bristol Serviced Lettings Ltd4
Price FromView Rooms
- Excellent
- 8 guest reviews
"I stayed here for a weekend visiting friends in bristol, was a pleasent experience, was supprised with how big my appartment was. It was cle..."
"I recently spent two nights in a three-bedroom apartment at Bristol Service Lettings with some friends. We booked last minute and did not kn..."
"Excellent. Clean tidy spacious. Very quiet. Beautiful sleep. Well organised. Friendly service..."
"If you want somewhere central, clean and comfortable then these apartments are perfect. Close to the shops especially Cabot Circus and quiet..."
"Very luxurious and relaxing with everything you need close by. Secure parking included and free wifi. Would definately return..."
About the hotel
Situated just half a mile from Bristol city-centre, our luxury modern apartments in 'Beaufort Court' provide you with a fully-furnished home - including free wireless broadband access, secure courtyard parking, and a 42 flatscreen TV with over 140 channels. The apartments are conveniently located just half a mile from Cabot Circus and one mile from the main rail and bus stations. We are a superb value alternative to traditional hotel accommodation, providing freedom, independence, and convenience.
All of our apartments are furnished and decorated to an exceptionally high standard,providing you with a living / dining area and fully fitted kitchen which includes a washing machine, microwave, fridge/freezer, oven, hob and a full set of cutlery, plates and wine glasses. The furniture is modern and comfortable throughout. We are a child-friendly company, and will provide a travel cot free of charge should you need it. Secure Parking subject to availability @ £8/night/car (reservation needed).
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Showing Friday 27 March 2015 to Saturday 28 March 2015Change Search
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- Hotel Non-Smoking Throughout, Disabled Facilities
- Family friendly
- Cots available
- Parking
- Car parking available onsite
- Business
- Wi-Fi Available, Wi-Fi Available In Rooms
- In room entertainment
- Video/DVD Player, TV, Satellite TV, [Channels] News, [Channels] Foreign (European), [Channels] Foreign (Other), [Channels] Music, [Channels] Childrens, Radio
- In room facilities
- Tea/Coffee making facilities in each room, Hairdryer in each room, Iron And Board In Each Room
- Other
- Ground floor bedrooms
- Accessibility
- Disabled Access Public Areas, Disabled Access Bedrooms, Disabled toilets on ground floor, Wheelchair Access
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- From 15:00 hours
- Until 11:00 hours
- The LateRooms.com rates for Bristol Serviced Lettings Ltd in BRISTOL are the total price of the room and not the 'per person' rate. All prices are inclusive of all local taxes.
- Pets are not allowed
Customer Reviews
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100% would recommend it to a friend
Customer service
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Lovley place to stay
I stayed here for a weekend visiting friends in bristol, was a pleasent experience, was supprised with how big my appartment was.
It was clean and had everything i needed . I will be using again when i next come to Bristol. Very Impressed and a joy to stay there .
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Lovely Apartment
I recently spent two nights in a three-bedroom apartment at Bristol Service Lettings with some friends.
We booked last minute and did not know much about the accommodation we had arranged but suffice to say we were very pleasantly surprised. The apartment was very spacious and spotless throughout. It was decorated beautifully and we felt very at home. Olga (reception) was extremely helpful and very understanding even though we were running late for our check-in. The atmosphere throughout the complex was very friendly. I would certainly visit again and highly recommend.
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Ontario Craft Beer week a celebration of suds
The fifth annual Ontario Craft Beer week kicks off Friday. Here's a look at the best events.
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With weather as nice as we've been getting lately, we probably didn't need another excuse to get out onto a patio and have a few beers.
But that's just what we've gotten, thanks to the fifth annual Ontario Craft Beer Week, which kicks off Friday. The festival runs from June 13-21, and has more than 300 events at over 100 venues around the province.
There are food and beer pairing events, meet-the-brewmaster sessions, a Father's Day barbecue and a doozy of a beer festival right at Yonge-Dundas Square.
Here's a look at some of the highlights, listed day by day. (For full event listings, visit the official OCB week website).
Friday June 13: Griffin Session Toronto: Ever wanted to try a beer brewed by a literary legend? This festival, which serves as the official opener to OCB Week, is your chance. The festival, which runs from 6-10 p.m. at Yonge-Dundas Square, features collaborative brews which saw brewers from across the province paired up with people from the cultural world. Top of that list would be Margaret Atwood, who teamed up with Beau's All-Natural Brewing to brew a spiced ale known as a gruit (as of press time, they still hadn't had the good sense to call it The Handmaid's Ale). Tickets are $39.50 apiece and can be purchased online at sessiontoronto.com/tickets.html
Saturday June 14: Griffin Session continues at Yonge-Dundas Square from 5-9 p.m. Another fun one to check out (although it could be a bit of a crowd) is at the LCBO at Yonge-Summerhill from 3:30-4:30 p.m. There, comedian Tom Green will be signing bottles of his very own Tom Green beer, a milk stout that won the people's choice award at last year's Session, and is now available at the LCBO. Another good choice, considering it's Father's Day weekend, is visiting the Amsterdam brewery (45 Esandar Dr.) where they're hosting a barbecue and brewery tour from 1-5 p.m.).
Sunday June 15: Want to give Dad an extra-special Father's Day? Bring him to the Beach BBQ and Brews festival, which runs from noon to 8 p.m. at Woodbine Park. There are brewers and barbecue specialists from across the province. Did we mention there's live music too? (The festival's also on Friday from 3-11 p.m. and Saturday from noon to 11 p.m.). Admission is free.
Monday June 16: Live in the east end and really love your locals? Live elsewhere, but would like to try some new spots? Then join the Danforth pub crawl, with representatives from six Ontario craft breweries hitting seven of the best east-end beer bars, starting at Relish (2152 Danforth Ave.) at 5:30 p.m. Visit the OCB week website for the full calendar.
Tuesday June 17: The kitchen team at the Mill Street brew pub shares some professional tips on cooking with beer (hint: it's about a lot more than just making a batter for fish and chips). From 6 to 8 p.m. at Mill Street's brew pub in the Distillery District.
Wednesday June 18: Beau's Beer Dinner at the Wren (1382 Danforth Ave.) Beau's All Natural Brewing co-founder Steve Beauchesne presents a four-course beer dinner at one of the Danforth's coziest beer spots. Tickets are $40 (including food and beer); call (647) 748-1382 or email firstname.lastname@example.com .
Thursday June 19: Meet the GLB Faces at Hungry Brew Hops (211 Main St. S., Newmarket). Wanna know what champions look like? Come and meet the team from Great Lakes Brewing, which recently took home its second consecutive Canadian Brewery of the Year title. Head brewer Mike Lackey, owner Peter Bulut Jr. and several other GLB staffers will be bringing a special selection of brews to northern York Region's hottest new beer bar. Admission is free.
Friday June 20: Summer Nights in the City at C'est What (67 Front St. E.). Five cottage country breweries bring their top picks for summer brews to the heart of downtown Toronto, and one of the city's most venerable craft beer bars. Try them all (in moderation, of course), and talk to some of the folks from the breweries. Admission to the event (which runs 5-9 p.m.) is free.
Saturday June 21: What fun would a beer week be without at least a few games? The An Sibin pub (709 Queen St. E.) hosts its annual Thirsty Games from 4-11 p.m. There's also an outdoor barbecue, and craft beer sampling.
Email Josh Rubin firstname.lastname@example.com or follow him on Twitter @starbeer
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