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During Nashville's Snowpocalypse, JD McPherson squeezed his entire band into the LC Studio to help warm up the city via the Lightning 100 air waves. Click here to watch JD McPherson perform "North Side Gal", "Dimes for Nickels", and "Bossy". Stay tuned, we have more videos on the way!
In-Studio Video Archive
We are posting as fast as possible, but until then you can find all of our videos on youtube.
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We are posting as fast as possible, but until then you can find all of our videos on youtube.
JD McPherson performing "North Side Gal", "Dimes for Nickels", and "Bossy"
Laura Reed performing "Wake Up" and "Struggle"
Laura Reed stopped to debut a few tunes with producer Shannon Sanders. Laura just released The Awakening on vinyl. Check out this video performance of "Wake Up" and "Struggle" live on 100.1 FM. If you want to hear more from Laura Reed, click here to listen to the full audio interview.
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Bernhoft performing "Come Around" and "Esiwalk"
Grammy nominated artist Bernhoft joins us in the LC studio before his show at The High Watt. Jarle Bernhoft is a multi-instrumentalist from Norway. Bernhoft performs "Come Around" and "Esiwalk" from his recent release Islander. Are you amazed at Jarle's looping skills?
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Punch Brothers performing "I Blew It Off", "Boil Weevil", and "Magnet"
Where you lucky enough to get tickets to Punch Brothers sold out show at Ryman Auditorium? Lightning 100 had the guys back into the LC studio to debut a few new songs off their recent release The Phosphorescent Blues. Listen to the full interview below or watch the HD in-studio videos from the band. Want more in-studio videos from Punch Brothers? We've also got videos from "Rye Whiskey", "You Are", "Patchwork Girlfriend" and "Movement and Location".
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Turbo Fruits performing "The Way I Want You" and "No Reason to Stay"
Local rockers Turbo Fruits stopped by the studio to debut two new tracks off their upcoming release No Control. Their fourth album will drop on 4/20/15. Check out "The Way I Want You" and "No Reason to Stay" live from the LC studio! Turbo Fruits will be playing a free show for record store day at The Basement East.
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Guster performing "Simple Machine" and "Long Night"
After their recent debut on Family Guy, Guster stopped by the studio to debut some new songs off their latest release Evermotion. Check out Guster performing "Simple Machine" and "Long Night" live at LC studio. What do you think of the new tracks? Let us know in a comment below if you want to hear these tunes on Lightning 100.
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Boom Forest performing "All I Need" and "Silver Hair"
Boom Forest debuts two new songs off his upcoming sophomore release! Check out an acoustic version of "All I Need" and "Silver Hair" live from the LC Studio.
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Lousia Wendorff performing "Blank Space / Style" and Unglued"
Louisa Wendorff and Devin Dawson stop by the WRLT studio to perform their hit Taylor Swift mash-up Blank Space // Style! Would you like to see them start a band? Let us know in a comment below! Louisa also performed an original song "Unglued" off her EP Arrows available now on iTunes.
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Knox Hamilton performing "Work It Out" and "Rightfully So"
Have you been enjoying "Work It Out" on 100.1 FM? Knox Hamilton made their first visit to the LC Studio to chat with Wells Adams. Check out two acoustic songs from Knox Hamilton including "Work It Out" and "Rightfully So" live at Lightning 100.
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All Them Witches performing "Unreleased Song"
All Them Witches stopped by the studio after their sold out Nashville Sunday Night show at 3rd and Lindsley. Check out this unreleased acoustic track from All Them Witches.
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Alanna Royale performing "18" and "Cop Show"
Alanna Royale visits the LC studio to talk about her recently release Achilles. We fit all six members into the studio to perform "18" and "Cop Show". Make sure to request Alanna Royale during the615 or lunch request hour if you would like to hear more from this Nashville band. Click here if you want to hear the full interview with Lt. Dan.
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John Butler Trio performing "Spring To Come" and "Better Than"
John Butler Trio stopped by the LC studio before their show at Ryman Auditorium. Check out this performance featuring their new single "Spring To Come" and a Lightning 100 favorite "Better Than" live in the studio.
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Sugar and the Hi-Lows performing "Snow Angel"
Trent Dabbs and Amy Stroup stop by the LC studio before their performance at Nashville Sunday Night. Sugar and The Hi-Lows perform "Snow Angel" live and debut a demo of their new song "High Rollers". Hope you enjoy this holiday treat! Click here to watch the HD performance or listen to the full interview via soundcloud.
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*Repeat Repeat performing "I'm Not the One" and "Hooks"
"That was the most rockstar things I've seen in the studio this year" said Wells Adams. *Repeat Repeat stopped by LC Studio to play a few new tunes. See what happens when the microphone starts falling during a live in-studio performance. Click here to watch a special version of "I'm Not The One" and "Hooks" which put Jared on his knees for the sake of rock and roll.
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Bahamas performing "Stronger Than That" and "Bitter Memories"
Afie Jurvanen aka Bahamas stopped by the LC studio while on his Fall tour. It is not the first time Afie has stopped by the studio, click here to see the performance of "Caught Me Thinking" and "Already Yours" off Pink Strat. Bahamas debuts "Stronger Than That" and "Bitter Memories" off their recent release Bahamas is Afie. Bahamas will return to Nashville on January 17th to Mercy Lounge.
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Nashville Sunday Night – JOHNNYSWIM performing "Home" and "Diamonds"
Said to embody the "tradition of the well-traveled singer-songwriter while cultivating a modern style that's uniquely their own", Johnnyswim made waves at Lightning 100's Nashville Sunday Night, Live from 3rd & Lindsley.
Abner Ramirez and Amanda Sudano, the now Los Angeles-based husband-and-wife duo, initially met at a church service in Nashville, but did not begin songwriting together until four years later. After three different EPs, 2014 saw the release of Johnnyswim's first ever full-length album, Diamonds. This week's video episode of the pair's June performance at Nashville Sunday Night features "Home" and "Diamonds" from their new album, two songs that you may have heard on Lightning 100.
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Spoon performing "Do You" and "Rainy Taxi"
Spoon stops by the LC studio just to say "hello" to their friends at Lightning 100. A few lucky listeners got to watch this in-studio performance of "Do You" and "Rainy Taxi" off their recent release They Want My Soul. Have you listened to the full album? Let us know by leaving a comment on this post if you want to hear another track on 100.1 FM! Click here to watch the HD performance or listen to the full audio interview.
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James Bay performing "If You Ever Wanna Be In Love" and "Let It Go"
Some lucky Lightning 100 listeners got a chance to sit in on a James Bay (not so) secret show that took place before his two sold out shows with Hozier in Nashville at Exit/In. Bay played four songs including "If You Ever Wanna Be In Love", "Let it Go" off of his new EP, "Move Together" and "When We Were On Fire". Lightning 100 was able to capture video of the first two songs. Click here to check the performance out.
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Ásgeir performing "Going Home" and "King and Cross"
A few weeks ago, Lightning 100 was lucky enough to have Asgeir stop by for a visit on his way to play a Not-So-Secret Secret Show at 12th and Porter. The 22-year-old phonem from Iceland chatted with our own Lt. Dan and played two songs, "Going Home" and "Leyndarmal"—the original Icelandic version of his hit "King and Cross."
Asgeir hails from a hamlet called Laugarbakki, about as remote a location as you can imagine producing a prodigious artist. "My town is about 40, 50 people," he told Lt. Dan. "I grew up with Internet, but we didn't have CD stores, or music stores, or venues. Even guitar strings, we had to drive three hours to get that." Even so, he was able to develop prodigious songwriting skills, and his first album, Dýrð í dauðaþögn, broke several Icelandic sales records—it is estimated that ten percent of the country's population purchased the LP. Working with American expatriate John Grant, he translated the original lyrics (written by his father) into English and released the album online as In the Silence in October 2013. For the most part, Asgeir feels as though the team was able to ensure that no meaning was lost in the translation. "[Grant] helped us a lot with it," he said, "and kind of to get the same poetic lyrics into English it was kind of a difficult job, but he did a good job on that." In the Silence has done well over the past year and spawned the single "King and Cross," which has received regular airplay on Lightning 100 since its release.
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First Aid Kit performing "Silver Lining" and "Stay Gold"
Swedish folk duo First Aid Kit, comprised of sisters Johanna and Kiara Söderberg, stopped by the LC Studio the day after their packed out show at the Ryman. It was their first time ever performing at the Ryman and the sisters said it was "a dream come true to play there". They performed the songs Silver Lining, the track you've been hearing on Lightning 100, and the title track to their new album Stay Gold in the studio.
Mike Mogis of Bright Eyes, who has been a big inspiration to the girls at an early age, produced their third album, Stay Gold, which was released back in June. "Hearing their music was like opening a door to all this folk and country music", the girls said about Bright Eyes. They have also had the opportunity to work with Jack White, who they did a cover of his song Love Interruption during their show at the Ryman, and got to tour with him in Europe back in 2012.
Here are the videos of their live in studio performances of Silver Lining and Stay Gold.
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Hozier performing "Take Me To Church" and "To Be Alone"
Lightning 100 was able to hook up a few lucky listeners for a private performance with Hozier over at William Colliers. Hozier sold out two night stand at Exit/In and then Ryman Auditorium within the first year of his debut album. Guess who played his single first? To thank Lightning 100, Hozier performed "To Be Alone" and his hit single "Take Me To Church". Click here to watch the HD video performance!
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Nashville Sunday Night – LP performing "Night Like This" and "Tokyo Sunset"
"What I love about Nashville is that there's such a sense of family here," claims Los Angeles-based singer/songwriter LP (Laura Pergolizzi) as she sits in Nashville's own Peter Nappi, a premium Tuscan leather footwear and goods boutique. Born and raised in New York, LP first began her career as a musician in 1998 when she was seen performing by David Lowery of the band Cracker, who later began to help her produce her debut album Heart-Shaped Scar. As her career escalated, LP eventually landed a record deal with Warner Bros. Records, which ultimately lead to the release of her most recent album Forever for Now.
This past September, LP performed at Lightning 100's Live On The Green Music Festival as well as Lightning 100's weekly concert series Nashville Sunday Night, a live broadcast live from 3rd and Lindsley. "Night Like This", the leading single from her 2014 album Forever for Now, received airplay on Lightning 100 and was a huge hit during her performance of the song at Nashville Sunday Night. "Night Like This was really fun last night…it was the first time I had seen people really respond to that song," LP says in this week's video episode of the live broadcast, "it was more of a communal thing", she remarks, "I enjoy that part of it."
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Vinyl Thief performing "Faces"
Lightning 100 recently had Vinyl Thief into the LC studio before #BlocktoberFest. You've been hearing "Middle of the Night" on 100.1 FM, now hear a live version and "Faces" off their recently release Phantoms. Vinyl Thief is offering a free download of "Middle of the Night" on their Facebook page. See Vinyl Thief live on November 8th at Stone Fox.
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Scars on 45 performing "Golden" and "Crazy for You"
Scars on 45 return to studio to talk about the release of their sophomore album Safety in Numbers. They first visited the WRLT studio in 2011, click here to check out their performance of "Give Me Something". We recorded two new in-studio videos including single "Crazy For You" and "Golden" off Safety in Numbers live in LC Studio on 100.1 FM. Lt. Dan also posted the full audio interview via SoundCloud. Hurry up and get your tickets to see them live this Saturday at Lightning 100's #BlocktoberFest featuring Walk the Moon, sElf, Boom Forest, repeat repeat, Vinyl Thief, Tristen, and Scars on 45!
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Erin McCarley and Boom Forest performing "Let Me Love You"
Erin McCarley and Boom Forest debut "Let Me Love You" in the LC studio on 100.1 FM. Boom Forest will be performing at Lightning 100's Blocktober Fest on October 18th with Walk the Moon, Self, repeat repeat, Tristen and Vinyl Thief. Hurry up and get your discount tickets to the show.


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Jawatan Kosong Lembaga Getah Malaysia (LGM) Julai Ogos 2013
Lembaga Getah Malaysia – LGM or The Malaysian Rubber Board – MRB is the custodian of the rubber industry in Malaysia. Established on 1 January 1998, it has under its fold three well established agencies (RRIM, MRRDB and MRELB), which are now merged into one, which have contributed significantly to the development of the rubber industry for the last 78 years.The R&D excellence in NR, accomplished by the Rubber Research Institute of Malaysia (RRIM), has had an impact on the Malaysian NR industry and other NR producing countries.
The primary objective of MRB is to assist in the development and modernisation of the Malaysian rubber industry in all aspects from cultivation of the rubber tree, the extraction and processing of its raw rubber, the manufacture of rubber products and the marketing of rubber and rubber products.
Jawatan Kosong Lembaga Getah Malaysia (LGM) :
Qualified Malaysian citizens invited to fill a vacancies at Lembaga Getah Malaysia as follows :
- Pegawai Penyelidik Q41
- Penolong Jurutera J29
- Penolong Pegawai Penyelidik Q27
- Penolong Pegawai Penguatkuasa N27
- Pembantu Tadbir (Perkeranian/Operasi) N17
- Pembantu Penyelidik Q17
- Juruteknik J17
- Pengawal Keselamatan KP11
- Operator Loji R3
- Pekerja Awam R1
How to apply
Please apply your application online through :
Further information and how to apply, please follow :
Jawatan Kosong LGM closing Date : 04 Ogos 2013
More Jobs Available :
- Jawatan Kosong Kiosk Krew April 2015
- Jawatan Kosong Filing Clerk April 2015
- Jawatan Kosong Financial Service Consultant April 2015
- Jawatan Kosong Clerk & Tutor April 2015
- Jawatan Kosong Driver cum Despatch April 2015
- Jawatan Kosong Technical Manager April 2015
- Jawatan Kosong Project Manager (Construction) April 2015
- Jawatan Kosong Project Sales Engineer April 2015
- Jawatan Kosong Sales Admin & Logistic Executive April 2015
- Jawatan Kosong Officer Supervisor cum Administrator April 2015
Join Our Facebook Community
Advertisements and any job vacancies displayed on this blog has nothing to do with us. We only convey information about this ads from the original job offer. Maybe no advertising and information office we show in this blog about exactly. We not be responsible on any problems that occur through advertisements offered and displayed on this blog.
Thus, any application, questions, confusion and any problems you may have regarding the position you are interested, please inquire directly to the department, ministry or company that advertises the vacancy, either by email, websites, phone numbers, etc. provided by them.
To visitor who wish to apply for available positions please click the link provided in the ads and please follow the instructions given to know how the means to leave any comments how to apply. Do not disclose your personal information to public. We not be liable for all personal information that disclosed.
You can help your friend or the other by share this Jawatan or Job Vacancy by facebook , twitter or other your social media.
Best Regards

subset: commoncrawl


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Ornamenta is an Italian ceramics brand. All of its products are made in Italy.02.10.15
Victoria-based firm Archiblox offers the very best in architect designed, prefabricated modular building solutions. They are completed in 12-28 weeks.02.10.15
Born from playful experimentation with vintage lighting components, Apparatus is a New York based design studio. Aged brass, etched glass, leather, and porcelain are combined to create lighting...02.09.15
Cuffhome is a Los Angeles-based design firm and product line. Lead designer Wendy Schwartz founded her namesake studio Wendy Schwartz Design in 2000, working primarily on residential interiors...02.09.15
Calico Wallpaper
Calico Wallpaper is a designer of bespoke wallpaper. It was founded in Brooklyn, New York in 2013 by creative and life-partners Rachel and Nick Cope. Their process combines artisanal methods from...02.09.15
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Since 2005, L. McComber has been dedicated to designing unique concepts of varied scope and context. From designing built-in furnitures and interiors to multi-units dwelling and adapting existing...02.09.15
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PETITE FRITURE, design editor created in 2009, was born with the will to promote young talents, and to develop with them a catalogue of objects, lighting and small furniture that creates a...02.09.15
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In the world of contemporary design, Wendy Raizin is known for her fresh, clean-lined approach to redefining space. Her notable skill in conceptual design has earned her a reputation as one of the...02.08.15
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O'Connor and Houle Architecture is an architecture, interior design, landscape and urban design practice located in inner city Melbourne. The firm undertakes a wide range of projects...02.08.15
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A pioneer of monumental textile installation, Maya Romonoff (founded by the titular Romonoff as a textile manufacturer in 1970) uses a deep knowledge of ancient craft techniques and ability to...02.06.15


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From IF YOU BUILD IT, a Long Shot Factory Release 2014.
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The organic test surface of one species was densely pitted with imprints, which the researchers interpreted as representing mineral grains of various types, including quartz, which subsequently dissolved. Agglutinated particles, presumed to be clay minerals, survived only in one specimen.
"Our observations demonstrate that coccoliths, and probably also planktonic foraminiferan tests, reach the Challenger Deep intact," said Gooday. "These particles were probably transported to these extreme depths in rapidly sinking marine snow, the aggregated remains of phytoplankton that lived in the sunlit surface ocean, or in faecal pellets from zooplankton."
It seems likely, therefore, that at least some agglutinated foraminifera living at extreme hadal depths build their homes from material that sinks down from the ocean above, rather like manna from heaven.
|Contact: Dr Rory Howlett
National Oceanography Centre, Southampton (UK)


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Recent Stories
- Science Day at Heysham Power Station
- New Head of Physics
- Keswick School rockets to success in STEM Challenge day
- Major feat of engineering opens doors to future
- New Business Partnerships and Enterprise Deputy Director in post
- New guidelines to support research fellowships
- Strategic partnership with Danish university to boost research collaboration
- A decade of 'Innovation, Interaction and Impact': InfoLab21 turns Ten Years Old
- The scientific method and the Higgs Boson
- Physics student wins blogging award
Seed Treatment Discovery Could Cut Pesticide Use
Story supplied by LU Press Office
Lancaster Environment Centre researchers have discovered a potential new way of making crops more resilient to pests by treating seeds with jasmonic acid.
Jasmonic acid (JA) is one of a plant's natural defences against being eaten. When a bug takes a bite of one of its leaves, JA is one of the chemical signals that warn other leaves to mobilise their pest defences - making them difficult to digest.
It has long been understood that by spraying crops with JA plants stand a better chance of repelling pests like mites, caterpillars and aphids - however sprayed plants grow less well.
But scientists working at Lancaster University have found that plants grown from seeds first dipped in JA are also more pest-resilient without any loss of growth.
This would be financially beneficial for farmers and growers - as seeds are cheaper to treat than entire crops. It is another tool for growers to use as an alternative to using large amounts of pesticides or GM technologies.
In early trials the best results were on tomato plants, where attacks by red spider mites were reduced by 80 per cent, aphid attack was reduced by 60 per cent and caterpillar damage was down by a third.
Good results were also obtained on sweet pepper where aphid attacks were reduced by 70 per cent, and caterpillar damage to wheat was reduced by 65 per cent. Meanwhile on maize, caterpillar damage was reduced by 38 per cent.
The original work was carried out in a number of projects funded by the Natural Environment Research Council and the Horticultural Development Council.
Dr Nigel Paul of Lancaster University, who led the research said: "We were investigating the mechanisms by which wild plants defend themselves against pest attack to get a better understanding of what works in nature. We were spraying the leaves of our plants with JA and wondered what would happen if we treated the seeds instead.
"It seemed unlikely that it would work but we were amazed to discover that it did - tomato plants were protected for about two months after they germinated."
Results from large scale field trials are due at the end of the year. In the meantime, with new funding from Defra, the team at Lancaster - including Nigel Paul, Mike Roberts and Jane Taylor - is developing new applications for the technology, including investigating its value in disease control.
By the end of the year, the University should know whether or not a commercial product will go into development.
Wed 15 October 2008
Associated Links
- Lancaster Environment Centre - Innovation, training and research for a sustainable future
Latest News
Science Day at Heysham Power Station
A Faculty team representing science, technology, engineering and maths took part in EDF Energy's 'Science Day' on Saturday 21st March at Heysham Power Station.
Wed 25 March 2015
New Head of Physics
Professor Roger Jones has replaced Professor Peter Ratoff as Head of the Physics Department. Roger gained a PhD studying neutrino interactions at CERN and Fermilab before starting his career at CERN working at the Large Electron-Positron (LEP) Collider.
Tue 24 March 2015
Keswick School rockets to success in STEM Challenge day
As part of British Science week, 170 students from 14 schools across the region came to Lancaster University on Wednesday 18th March to compete in science, technology, engineering and mathematics challenges.
Mon 23 March 2015
Major feat of engineering opens doors to future
Lancaster University's new flagship Engineering Building will provide a beacon of excellence for research and recruitment for the UK's buoyant and significant engineering industry.
Mon 23 March 2015


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May 30, 2012 · SOAL-SOAL NARRATIVE PILIHAN GANDA ... This text is for no. 6 to 12. SANGKURIANG . ... Ujian Praktek SMA kelas XII; - read more
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I have a question about the recipe "parippu vada or dal vada a common street food of Kerala" from pauljoseph. What are curry leaves? Do I find them at an Indian grocery store (and fresh or dried)? Thank you.
Some links to info on curry leaves...They're available fresh at most Indian grocery stores,
& a previous pickle thread from a couple of weeks ago
Panfusine thank you for answering that question lots of people ask me where they get curry leaf in America
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Royals bring back familiar face in Ibanez; DFA Maxwell, Ciriaco
KANSAS CITY, Mo. -- Seeking to improve the Royals' bench, general manager Dayton Moore signed veteran Raul Ibanez, who resurrected his career in Kansas City, and called up utility infielder Christian Colon, the team's top pick in 2010. Ibanez, 42, will give the Royals a veteran left-handed bat off the bench for now, as well as depth in right field, left field and even first base...
Via Fox Sports Kansas City
June 30, 2014 | Discuss
Pine Tar Podcast w/ Todd Gold of Perfect Game
After a rough couple games with the White Sox this week David and Clint decide to turn to 2014 MLB draft talk. What better guest to have on to talk draft than Perfect Game's scouting director Todd Gold who talks a few prep arms and college bats including some that the Royals could be intrigued by. Also David and Clint discuss the Justin Maxwell, Johnny Giavotella demotions and how...
Via Pine Tar Press
May 21, 2014 | Discuss
Royals bring up Coleman, designate Maxwell
KANSAS CITY, Mo. -- The Royals selected the contract of right-hander Casey Coleman from Triple-A Omaha and designated outfielder Justin Maxwell for assignment before Friday night's game against Baltimore. The 26-year-old Coleman was released by the Cubs on April 14 and signed the next day by the Royals. He appeared in seven games for Omaha, going 1-0 with a 1.50 ERA. Coleman is the...
Via Fox Sports Kansas City
Royals designate OF Justin Maxwell for assignment
getty images On Friday the Kansas City Royals designated outfielder Justin Maxwell for assignment. Maxwell was hitting just .138/.219/.172 with no homers over his first 32 plate appearances this season before his release. He has the ability to play all three outfield spots. Maxwell is a career .225/.312/.420 hitter with 34 home runs and 106 RBI in 337 games. Someone will give the...
Via Tireball.com
Royals DFA Justin Maxwell, Promote Casey Coleman
The hero from the end of the Kansas City Royals home schedule last year, Justin Maxwell, has been designated for assignment as the Royals elected to call up Casey Coleman from Omaha to add depth to the bullpen. Maxwell was acquired last season for minor leaguer Kyle Smith at the trade deadline to add power to a Royals team bereft of it and he was quite good in 35 games, hitting ...
Via Pine Tar Press
Maxwell collects three hits, Royals tie A's 9-9
SURPRISE, Ariz. -- Dan Straily worked four promising innings, Derek Norris and Michael Taylor homered and the Oakland Athletics and Kansas City Royals played to a 9-9 tie in nine innings Friday. A's manager Bob Melvin said before the game starters Jarrod Parker and A.J. Griffin are in "jeopardy" of beginning the season on the disabled list with arm injuries. Straily, who won 10 games...
Via Fox Sports Kansas City
March 14, 2014 | Discuss
Royals reach deal with Maxwell, avoid arbitration
Outfielder Justin Maxwell and the Kansas City Royals agreed to a one-year contract worth $1,325,000, leaving closer Greg Holland and reliever Aaron Crow as their only unsigned players in arbitration. Maxwell gets a substantial raise from the $492,500 he made last year. He was asking for $1.7 million and the Royals had offered $1,075,000. Kansas City previously agreed to one-year...
Via AP on Fox
Royals avoid arbitration with Justin Maxwell
The Kansas City Royals have avoided arbitration with outfielder Justin Maxwell. Maxwell, 30, was eligible for arbitration for the first time. He had asked for $1.7 million while the Royals had offered $1.075 million when figures were exchanged recently. Acquired mid-season from Houston, Maxwell compiled a .252/.328/.436 line last season with seven home runs and 25 RBI in 75 games...
Via Tireball.com
Royals sign Justin Maxwell, avoid arbitration
KANSAS CITY, Mo. -- Outfielder Justin Maxwell, projected to be the Royals' fourth or fifth outfielder this season, signed a one-year deal with the club, thus avoiding arbitration. Maxwell was asking for $1.7 million, and a club source confirmed Maxwell received $1.325 million. The Royals had offered $1.075 million last week when the two sides exchanged arbitration figures. Maxwell...
Via Fox Sports Kansas City
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Are you John D Pfeifer?Claim your profile
Publications (133)473.75 Total impact
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ABSTRACT: The BRAF mutation occurs commonly in papillary thyroid carcinoma (PTC). Previous investigations of its utility to predict recurrence-free survival (RFS) and disease-specific survival (DSS) have reported conflicting results and its role remains unclear. The purpose of this retrospective study was to determine the incidence of the BRAF mutation and analyze its relationship to clinicopathologic risk factors and long-term outcomes in the largest, single-institution American cohort to date. BRAF mutational status was determined in 508 PTC patients using RFLP analysis. The relationships between BRAF mutation status, patient and tumor characteristics, RFS, and DSS were analyzed. The BRAF mutation was present in 67% of patients. On multivariate analysis, presence of the mutation predicted only for capsular invasion (HR, 1.7; 95% CI, 1.1-2.6), cervical lymph node involvement (HR, 1.7; 95% CI, 1.1-2.7), and classic papillary histology (HR, 1.8; 95% CI 1.1-2.9). There was no significant relationship between the BRAF mutation and RFS or DSS, an observation that was consistent across univariate, multivariate, and Kaplan-Meier analyses. This is the most extensive study to date in the United States to demonstrate that BRAF mutation is of no predictive value for recurrence or survival in PTC. We found correlations of BRAF status and several clinicopathologic characteristics of high-risk disease, but limited evidence that the mutation correlates with more extensive or aggressive disease. This analysis suggests that BRAF is minimally prognostic in PTC. However, prevalence of the BRAF mutation is 70% in the general population, providing the opportunity for targeted therapy. © 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.Cancer Medicine 02/2015; DOI:10.1002/cam4.417
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ABSTRACT: Context .- Genomic sequencing for cancer is offered by commercial for-profit laboratories, independent laboratory networks, and laboratories in academic medical centers and integrated health networks. The variability among the tests has created a complex, confusing environment. Objective .- To address the complexity, the Personalized Health Care (PHC) Committee of the College of American Pathologists proposed the development of a cancer genomics resource list (CGRL). The goal of this resource was to assist the laboratory pathology and clinical oncology communities. Design .- The PHC Committee established a working group in 2012 to address this goal. The group consisted of site-specific experts in cancer genetic sequencing. The group identified current next-generation sequencing (NGS)-based cancer tests and compiled them into a usable resource. The genes were annotated by the working group. The annotation process drew on published knowledge, including public databases and the medical literature. Results .- The compiled list includes NGS panels offered by 19 laboratories or vendors, accompanied by annotations. The list has 611 different genes for which NGS-based mutation testing is offered. Surprisingly, of these 611 genes, 0 genes were listed in every panel, 43 genes were listed in 4 panels, and 54 genes were listed in 3 panels. In addition, tests for 393 genes were offered by only 1 or 2 institutions. Table 1 provides an example of gene mutations offered for breast cancer genomic testing with the annotation as it appears in the CGRL 2014. Conclusions .- The final product, referred to as the Cancer Genomics Resource List 2014, is available as supplemental digital content.Archives of pathology & laboratory medicine 12/2014; DOI:10.5858/arpa.2014-0330-CP · 2.88 Impact Factor
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ABSTRACT: BACKGROUNDA clinical assay was implemented to perform next-generation sequencing (NGS) of genes commonly mutated in multiple cancer types. This report describes the feasibility and diagnostic yield of this assay in 381 consecutive patients with non–small cell lung cancer (NSCLC).METHODS Clinical targeted sequencing of 23 genes was performed with DNA from formalin-fixed, paraffin-embedded (FFPE) tumor tissue. The assay used Agilent SureSelect hybrid capture followed by Illumina HiSeq 2000, MiSeq, or HiSeq 2500 sequencing in a College of American Pathologists–accredited, Clinical Laboratory Improvement Amendments–certified laboratory. Single-nucleotide variants and insertion/deletion events were reported. This assay was performed before methods were developed to detect rearrangements by NGS.RESULTSTwo hundred nine of all requisitioned samples (55%) were successfully sequenced. The most common reason for not performing the sequencing was an insufficient quantity of tissue available in the blocks (29%). Excisional, endoscopic, and core biopsy specimens were sufficient for testing in 95%, 66%, and 40% of the cases, respectively. The median turnaround time (TAT) in the pathology laboratory was 21 days, and there was a trend of an improved TAT with more rapid sequencing platforms. Sequencing yielded a mean coverage of 1318×. Potentially actionable mutations (ie, predictive or prognostic) were identified in 46% of 209 samples and were most commonly found in KRAS (28%), epidermal growth factor receptor (14%), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (4%), phosphatase and tensin homolog (1%), and BRAF (1%). Five percent of the samples had multiple actionable mutations. A targeted therapy was instituted on the basis of NGS in 11% of the sequenced patients or in 6% of all patients.CONCLUSIONSNGS-based diagnostics are feasible in NSCLC and provide clinically relevant information from readily available FFPE tissue. The sample type is associated with the probability of successful testing. Cancer 2014. © 2014 American Cancer Society.Cancer 10/2014; 121(4). DOI:10.1002/cncr.29089 · 5.20 Impact Factor
Dataset: mmc1
Dataset: mmc3
Dataset: mmc4
Dataset: mmc2
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ABSTRACT: Purpose:The practice of "genomic" (or "personalized") medicine requires the availability of appropriate diagnostic testing. Our study objective was to identify the reasons for health systems to bring next-generation sequencing into their clinical laboratories and to understand the process by which such decisions were made. Such information may be of value to other health systems seeking to provide next-generation sequencing testing to their patient populations.Methods:A standardized open-ended interview was conducted with the laboratory medical directors and/or department of pathology chairs of 13 different academic institutions in 10 different states.Results:Genomic testing for cancer dominated the institutional decision making, with three primary reasons: more effective delivery of cancer care, the perceived need for institutional leadership in the field of genomics, and the premise that genomics will eventually be cost-effective. Barriers to implementation included implementation cost; the time and effort needed to maintain this newer testing; challenges in interpreting genetic variants; establishing the bioinformatics infrastructure; and curating data from medical, ethical, and legal standpoints. Ultimate success depended on alignment with institutional strengths and priorities and working closely with institutional clinical programs.Conclusion:These early adopters uniformly viewed genomic analysis as an imperative for developing their expertise in the implementation and practice of genomic medicine.Genet Med advance online publication 10 July 2014Genetics in Medicine (2014); doi:10.1038/gim.2014.60.Genetics in medicine: official journal of the American College of Medical Genetics 07/2014; DOI:10.1038/gim.2014.60 · 3.92 Impact Factor
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ABSTRACT: Background Clinical outcome of papillary thyroid carcinoma (PTC) in children differs significantly from that of adults. There is no clear explanation of this difference although previous studies have demonstrated a lower prevalence of the BRAFV600E mutation in PTC of children. However, data are limited due to the rarity of this diagnosis. BRAFV600E mutation prevalence and its relationship with outcome in pediatric PTC remain unclear.ProcedureBRAFV600E mutational status was determined in 27 PTC patients less than 22 years of age using restriction fragment length polymorphism (RFLP) analysis. The relationship between BRAFV600E mutation status, patient and tumor characteristics as well as progression-free survival (PFS) were analyzed.ResultsBRAFV600E was present in 63% of patients and occurred more often in male patients versus females (P = 0.033). Presence of the mutation did not correlate with any difference in extent of disease at diagnosis, tumor size, capsular invasion, vascular invasion, soft tissue invasion, or margin status. At 10 years, PFS for BRAFV600E positive versus negative patients was 55.5% versus 70.0%, respectively (P = 0.48). Overall survival was 100% and median follow-up was 13.9 years.Conclusions This study of pediatric PTC demonstrates that BRAFV600E mutations occur in children at a rate comparable to adults. We found a correlation of BRAFV600E with the male gender, but no evidence that the mutation correlates with more extensive or aggressive disease. This analysis suggests that differences in disease course of PTC in children versus adults are not strongly dependent upon the presence of the BRAFV600E mutation. Pediatr Blood Cancer © 2014 Wiley Periodicals, Inc.Pediatric Blood & Cancer 07/2014; DOI:10.1002/pbc.24935 · 2.35 Impact Factor
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ABSTRACT: Although the presence of the t(12;22)(q13;q12) translocation (the defining molecular feature of malignant melanoma of soft parts/clear cell sarcoma) in cutaneous melanoma has been investigated, no large-scale studies have been performed among mucosal melanoma (MucM). In this study we assessed the prevalence of the EWSR1 rearrangement in primary MucM, and analyzed gross and microscopic features with their potential impact on diagnosis and prognosis. Overall, 132 specimens from 84 patients were included. A total of 55 cases had an intramucosal component. Survival of MucMs of the head and neck was associated with two independent factors: size and histology. Tumors more than 3 cm in greatest dimension had an average survival of 12.75 months; those 3 cm or less had an average survival of 38.3 months (P=0.035). Purely epithelioid tumors had an average worse survival of 16.8 months (P=0.028). A cut-off value of 1 mm for Breslow depth provided a statistically significant difference in survival at both 3 and 5 years (P=-0.02) by multivariate analysis in the gynecologic tract. At the molecular level three cases had a EWSR1 rearrangement by fluorescent in-situ hybridization, but only one with an intramucosal component. None of the 58 cases tested by PCR showed the presence of the EWSR1 rearrangement. With the exception of vulvar melanomas, the prognosis of mucosal-associated melanomas was poor and there was a suggestion that spindle morphology may be more favorable. Our study also showed that the EWSR1 rearrangement was very uncommon among MucM. Though 'clear cell sarcoma' is embedded in the sarcoma literature, the synonym 'melanoma of soft parts' has considerable justification in light of our evolving understanding of the molecular genetics in the family of malignant melanomas.Melanoma Research 05/2014; 24(4). DOI:10.1097/CMR.0000000000000082 · 2.10 Impact Factor
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ABSTRACT: The identification of recurrent gene rearrangements in the clinical laboratory is the cornerstone for risk stratification and treatment decisions in many malignant tumors. Studies have reported that targeted next-generation sequencing assays have the potential to identify such rearrangements; however, their utility in the clinical laboratory is unknown. We examine the sensitivity and specificity of ALK and KMT2A (MLL) rearrangement detection by next-generation sequencing in the clinical laboratory. We analyzed a series of seven ALK rearranged cancers, six KMT2A rearranged leukemias, and 77 ALK/KMT2A rearrangement-negative cancers, previously tested by fluorescence in situ hybridization (FISH). Rearrangement detection was tested using publicly available software tools, including Breakdancer, ClusterFAST, CREST, and Hydra. Using Breakdancer and ClusterFAST, we detected ALK rearrangements in seven of seven FISH-positive cases and KMT2A rearrangements in six of six FISH-positive cases. Among the 77 ALK/KMT2A FISH-negative cases, no false-positive identifications were made by Breakdancer or ClusterFAST. Further, we identified one ALK rearranged case with a noncanonical intron 16 breakpoint, which is likely to affect its response to targeted inhibitors. We report that clinically relevant chromosomal rearrangements can be detected from targeted gene panel-based next-generation sequencing with sensitivity and specificity equivalent to that of FISH while providing finer-scale information and increased efficiency for molecular oncology testing.The Journal of molecular diagnostics: JMD 05/2014; DOI:10.1016/j.jmoldx.2014.03.006 · 3.48 Impact Factor
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ABSTRACT: Context.-Genomic medicine is revolutionizing patient care. Physicians in areas as diverse as oncology, obstetrics, and infectious disease have begun using next-generation sequencing assays as standard diagnostic tools. Objective.-To review the role of pathologists in genomic testing as well as current educational programs and future training needs in genomic pathology. Data Sources.-Published literature as well as personal experience based on committee membership and genomic pathology curricular design. Conclusions.-Pathologists, as the directors of the clinical laboratories, must be prepared to integrate genomic testing into their practice. The pathology community has made significant progress in genomics-related education. A continued coordinated and proactive effort will ensure a future vital role for pathologists in the evolving health care system and also the best possible patient care.Archives of pathology & laboratory medicine 04/2014; 138(4):498-504. DOI:10.5858/arpa.2013-0359-SA · 2.88 Impact Factor
Article: Stabilization of Disease after Targeted Therapy in a Thymic Carcinoma with KIT Mutation Detected by Clinical Next-Generation Sequencing.[Show abstract] [Hide abstract]
ABSTRACT: Precision medicine uses individually determined genomic information to guide treatment in cancer and other diseases. We have implemented a clinical genomics assay that uses targeted next-generation sequencing of 25 cancer-related genes to guide the use of targeted therapies in diverse malignancies. We report the case of a 55-year-old woman with a poorly differentiated squamous cell carcinoma of thymic origin, with disease progression after standard treatment. Targeted tumor sequencing revealed the presence of a KIT codon 579 deletion (p.D579del). This specific mutation has not previously been associated with thymic tumors, but has been reported in gastrointestinal stromal tumors and has been associated with response to imatinib. Imatinib therapy was instituted for and resulted in stabilization of disease. This case illustrates the potential of clinical next-generation sequencing to open unexpected avenues for treatment and thereby improve patient outcomes.Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer 02/2014; 9(2):e12-6. DOI:10.1097/JTO.0b013e3182a7d22e · 4.55 Impact Factor
Article: Lymphovascular Space Invasion in Microcystic Elongated and Fragmented (MELF)-Pattern Well-differentiated Endometrioid Adenocarcinoma is Associated With a Higher Rate of Lymph Node Metastasis.[Show abstract] [Hide abstract]
ABSTRACT: The microcystic elongated and fragmented (MELF) pattern of myoinvasion is a feature of some well-differentiated endometrial endometrioid adenocarcinomas that has been associated with poor prognosis. The myoinvasion in MELF-pattern tumors can be subtle and lead to underestimation of the depth of myometrial invasion resulting in tumor understaging; the presence of lymphvascular space invasion (LVSI) and lymph node metastasis in MELF-pattern tumors can also be subtle and lead to tumor understaging. To investigate the association of MELF-pattern invasion and lymph node metastasis, we reviewed a series of well-differentiated endometrioid adenocarcinomas and correlated the presence of MELF-pattern myoinvasion and LVSI with lymph node metastasis. Cases of T1 stage well-differentiated endometrioid adenocarcinomas with LVSI and a concurrent lymph node dissection were identified from departmental files. Hematoxylin and eosin-stained slides from the hysterectomy specimen and lymph nodes were reviewed for the presence of MELF-pattern myoinvasion, LVSI, and nodal metastasis. MELF-pattern myoinvasion was identified at least focally in 36% of cases. The pattern of LVSI differed between cases with MELF-pattern invasion and conventional-type invasion, as did the pattern of nodal metastasis. A statistically significantly higher rate of lymph node metastasis was present in cases with MELF-pattern invasion than in cases with conventional invasion, and the rate stratified with the proportion of MELF-pattern adenocarcinomas. MELF-pattern cases carry an increased rate of lymph node metastasis even within the subset of endometrioid tumors with LVSI, which has implications in routine clinical practice as it signals the importance of recognizing MELF-pattern myoinvasion.International journal of gynecological pathology: official journal of the International Society of Gynecological Pathologists 01/2014; DOI:10.1097/PGP.0b013e318285657b · 2.07 Impact Factor
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ABSTRACT: Targeted next-generation sequencing (NGS) provides predictive and prognostic information in the routine care of patients with cancer. However, with increasing knowledge of the biological basis of cancer, NGS of the same gene sets can also provide diagnostic information in challenging cases, on the basis of identification of both known and novel variants, including single-nucleotide variants, insertions and deletions, copy number alterations, and translocations. Here, we present 3 clinical cases in which targeted NGS of hybrid-capture-enriched DNA from formalin-fixed, paraffin-embedded tumor samples provided unique and clinically important diagnostic and/or staging information in 3 different challenging clinical scenarios. In the first patient, NGS played a key role in both diagnosis and staging in a patient with multiple tumors of the same histologic type. The second case demonstrates the ability of NGS to clarify the tumor tissue type in a single mass involving multiple organs, and thereby guide appropriate chemotherapy. The third case illustrates that information regarding susceptibility to targeted therapeutics can also clarify the original histologic diagnosis.The American journal of surgical pathology 01/2014; 38(4). DOI:10.1097/PAS.0000000000000161 · 4.59 Impact Factor
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ABSTRACT: Merkel cell carcinoma is a highly aggressive cutaneous neuroendocrine tumor that has been associated with Merkel cell polyomavirus in up to 80% of cases. Merkel cell polyomavirus is believed to influence pathogenesis, at least in part, through expression of the large T antigen, which includes a retinoblastoma protein-binding domain. However, there appears to be significant clinical and morphological overlap between polyomavirus-positive and polyomavirus-negative Merkel cell carcinoma cases. Although much of the recent focus of Merkel cell carcinoma pathogenesis has been on polyomavirus, the pathogenesis of polyomavirus-negative cases is still poorly understood. We hypothesized that there are underlying human somatic mutations that unify Merkel cell carcinoma pathogenesis across polyomavirus status, and to investigate we performed whole exome sequencing on five polyomavirus-positive cases and three polyomavirus-negative cases. We found that there were no significant differences in the overall number of single-nucleotide variations, copy number variations, insertion/deletions, and chromosomal rearrangements when comparing polyomavirus-positive to polyomavirus-negative cases. However, we did find that the retinoblastoma pathway genes harbored a high number of mutations in Merkel cell carcinoma. Furthermore, the retinoblastoma gene (RB1) was found to have nonsense truncating protein mutations in all three polyomavirus-negative cases; no such mutations were found in the polyomavirus-positive cases. In all eight cases, the retinoblastoma pathway dysregulation was confirmed by immunohistochemistry. Although polyomavirus-positive Merkel cell carcinoma is believed to undergo retinoblastoma dysregulation through viral large T antigen expression, our findings demonstrate that somatic mutations in polyomavirus-negative Merkel cell carcinoma lead to retinoblastoma dysregulation through an alternative pathway. This novel finding suggests that the retinoblastoma pathway dysregulation leads to an overlapping Merkel cell carcinoma phenotype and that oncogenesis occurs through either a polyomavirus-dependent (viral large T antigen expression) or polyomavirus-independent (host somatic mutation) mechanism.Modern Pathology advance online publication, 10 January 2014; doi:10.1038/modpathol.2013.235.Modern Pathology 01/2014; DOI:10.1038/modpathol.2013.235 · 6.36 Impact Factor
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ABSTRACT: The identification of recurrent gene rearrangements in the clinical laboratory is the cornerstone for risk stratification and treatment decisions in many malignant tumors. Studies have reported that targeted next-generation sequencing assays have the potential to identify such rearrangements; however, their utility in the clinical laboratory is unknown. We examine the sensitivity and specificity of ALK and KMT2A (MLL) rearrangement detection by next-generation sequencing in the clinical laboratory. We analyzed a series of seven ALK rearranged cancers, six KMT2A rearranged leukemias, and 77 ALK/KMT2A rearrangement–negative cancers, previously tested by fluorescence in situ hybridization (FISH). Rearrangement detection was tested using publicly available software tools, including Breakdancer, ClusterFAST, CREST, and Hydra. Using Breakdancer and ClusterFAST, we detected ALK rearrangements in seven of seven FISH-positive cases and KMT2A rearrangements in six of six FISH-positive cases. Among the 77 ALK/KMT2A FISH-negative cases, no false-positive identifications were made by Breakdancer or ClusterFAST. Further, we identified one ALK rearranged case with a noncanonical intron 16 breakpoint, which is likely to affect its response to targeted inhibitors. We report that clinically relevant chromosomal rearrangements can be detected from targeted gene panel–based next-generation sequencing with sensitivity and specificity equivalent to that of FISH while providing finer-scale information and increased efficiency for molecular oncology testing.
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ABSTRACT: Currently, oncology testing includes molecular studies and cytogenetic analysis to detect genetic aberrations of clinical significance. Next-generation sequencing (NGS) allows rapid analysis of multiple genes for clinically actionable somatic variants. The WUCaMP assay uses targeted capture for NGS analysis of 25 cancer-associated genes to detect mutations at actionable loci. We present clinical validation of the assay and a detailed framework for design and validation of similar clinical assays. Deep sequencing of 78 tumor specimens (≥1000× average unique coverage across the capture region) achieved high sensitivity for detecting somatic variants at low allele fraction (AF). Validation revealed sensitivities and specificities of 100% for detection of single-nucleotide variants (SNVs) within coding regions, compared with SNP array sequence data (95% CI = 83.4-100.0 for sensitivity and 94.2-100.0 for specificity) or whole-genome sequencing (95% CI = 89.1-100.0 for sensitivity and 99.9-100.0 for specificity) of HapMap samples. Sensitivity for detecting variants at an observed 10% AF was 100% (95% CI = 93.2-100.0) in HapMap mixes. Analysis of 15 masked specimens harboring clinically reported variants yielded concordant calls for 13/13 variants at AF of ≥15%. The WUCaMP assay is a robust and sensitive method to detect somatic variants of clinical significance in molecular oncology laboratories, with reduced time and cost of genetic analysis allowing for strategic patient management.The Journal of molecular diagnostics: JMD 11/2013; DOI:10.1016/j.jmoldx.2013.10.002 · 3.48 Impact Factor
Article: Performance of Common Analysis Methods for Detecting Low-Frequency Single Nucleotide Variants in Targeted Next-Generation Sequence Data.[Show abstract] [Hide abstract]
ABSTRACT: Next-generation sequencing (NGS) is becoming a common approach for clinical testing of oncology specimens for mutations in cancer genes. Unlike inherited variants, cancer mutations may occur at low frequencies because of contamination from normal cells or tumor heterogeneity and can therefore be challenging to detect using common NGS analysis tools, which are often designed for constitutional genomic studies. We generated high-coverage (>1000×) NGS data from synthetic DNA mixtures with variant allele fractions (VAFs) of 25% to 2.5% to assess the performance of four variant callers, SAMtools, Genome Analysis Toolkit, VarScan2, and SPLINTER, in detecting low-frequency variants. SAMtools had the lowest sensitivity and detected only 49% of variants with VAFs of approximately 25%; whereas the Genome Analysis Toolkit, VarScan2, and SPLINTER detected at least 94% of variants with VAFs of approximately 10%. VarScan2 and SPLINTER achieved sensitivities of 97% and 89%, respectively, for variants with observed VAFs of 1% to 8%, with >98% sensitivity and >99% positive predictive value in coding regions. Coverage analysis demonstrated that >500× coverage was required for optimal performance. The specificity of SPLINTER improved with higher coverage, whereas VarScan2 yielded more false positive results at high coverage levels, although this effect was abrogated by removing low-quality reads before variant identification. Finally, we demonstrate the utility of high-sensitivity variant callers with data from 15 clinical lung cancers.The Journal of molecular diagnostics: JMD 11/2013; DOI:10.1016/j.jmoldx.2013.09.003 · 3.48 Impact Factor
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ABSTRACT: Mutations in exon 2 of the MED12 gene have been reported in 50% to 70% of uterine leiomyomas. To determine the frequency of MED12 mutations in various types of smooth muscle tumors as well as normal uterine myometrium adjacent to a leiomyoma, we selected a total of 143 cases for analysis of MED12 exon 2 mutations by polymerase chain reaction and Sanger sequencing. MED12 mutations were detected in 54% of classical uterine leiomyomas (15/28) and in 15% of cases in myometrium adjacent to leiomyomas (2/13); 34% of leiomyoma/leiomyomatosis in pelvic/retroperitoneal sites (10/29); 0% of extrauterine leiomyomas (0/29); 8% of smooth muscle tumor of uncertain malignant potential (1/12); 30% of uterine leiomyosarcomas (6/20); and 4% of extrauterine leiomyosarcomas (1/25). Mutations were clustered around codons 44, 40, 41, and 36, and consisted primarily of single nucleotide substitutions and small in-frame deletions. Our results confirm the findings of similar recent studies and further show that pelvic and retroperitoneal leiomyomas harbor an increased frequency of MED12 mutations (34%) as compared with other extrauterine sites (0%; P = 0.0006), and that histologically unremarkable adjacent myometrium can harbor similar MED12 mutations. These findings suggest that smooth muscle tumors in pelvic/retroperitoneal sites are subject to the same mutational changes as those of uterine myometrium, and that these mutations may precede the gross or histological development of a leiomyoma.Human pathology 11/2013; 45(1). DOI:10.1016/j.humpath.2013.08.005 · 2.81 Impact Factor
Top Journals
Washington University in St. Louis
San Luis, Missouri, United States
- • Department of Pathology and Immunology
- • Department of Obstetrics and Gynecology
- • Department of Molecular Microbiology
Postgraduate Institute of Medical Education and Research
Chandīgarh, Union Territory of Chandigarh, India
- Department of NeuroSurgery
Barnes Jewish HospitalSan Luis, Missouri, United States
University of Washington Seattle
Seattle, WA, United States
- • Department of Pathology
- • Department of Immunology
University of Utah
Salt Lake City, UT, United States
- Department of Pathology
University of Alabama at BirminghamBirmingham, Alabama, United States
University of British Columbia - VancouverVancouver, British Columbia, Canada
St. Luke's Hospital (MO, USA)Saint Louis, Michigan, United States
Case Western Reserve University
Cleveland, OH, United States
- Institute of Pathology


text:
organic cotton & PLA
quilted mattress pad
Features & Benefits
- Luxurious Organic Cotton Fabric
- Filled with PLA Batting
- Provides an extra layer of cushion and absorption
for your child
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- Made in U.S.A.
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PT95: Twin w/Straps (38" x 75" x 1/2")
PF95: Full w/Straps (53" x 75" x 1/2")
PQ95: Queen w/Straps (60" x 80" x 1/2")
Who is This For?
The Organic Cotton Quilted Pad is like a "pillowtop" for your toddler or child. It is designed to simulate the feel of a quilted adult style bed. Makes a great addition to the waterproof side of the 2-in-1 Organic Cotton Ultra.


text:
Carl Sandburg
From The Shore
A lone gray bird,
Dim-dipping, far-flying,
Alone in the shadows and grandeurs and tumults
read full text »
Comments about this poem (From The Shore by Carl Sandburg )
Gangadharan Nair Pulingat (10/20/2014 8:48:00 AM)
Very interesting poem. How beautifully narrated the flying of birds in such adversities of nature and the poet sees the flying as glories of chance and hazards of death a great imagination. This is a marvelous poem. (Report) Reply
John Richter (10/20/2014 7:46:00 AM)
Interesting, I would say. Haven't each of us - at one time or another - sat in a beautiful place - alone - devoid of other soul's, and watched a bird glide in the steep winds? I have. Many times. I can't think of a more beautiful way to express such an encounter. I think that is the magic of Mr. Sandburg - his ability to reach into the reader and find commonality - and then enhance it by transferring the mundane into great wonder. (Report) Reply
John S (10/20/2013 8:44:00 PM)
He chose nice descriptive words:
Alone in the shadows and grandeurs and tumults, rapture of flight, eager and palpitant wings
The only thing that really, really bothers me about modern poetry is that the poets don't rhyme. That's just personal preference. I think a poem flows so much better when the lines rhyme. This poem got a 6.2 with 75 votes. With his beautiful, descriptive words if he'd have made this rhyme I think the score would be much higher! What do modern poets have against rhyming anyway? ? (Report) ReplyFrank Avon (10/20/2014 1:00:00 AM)
That IS just your personal perference. In most languages, in most eras, poems don't rhyme. Shakespeare wrote mostly in blank verse; so did Milton; e.g. 'Paradise Lost.' Wordsworth's 'Prelude, ' also. Eliot's 'Four Quartets.' Whitman's 'Leaves of Grass.' And so much rhyming poetry is BAD poetry. (Cf. John S on Joyce Kilmer's 'Stars.') Italian and French rhyme more smoothly than English, so the English tried to imitate them, but poets often have to twist and veer, wiggle and wriggle, to get a words that rhymes at the right times. Traditional syntax and natural vocal rhythms simply take a beating. So, please, respect MY persoanal preference. And for god's sake, quite teaching our children that pomes hafta rime. They don't.
Liliana ~el (10/20/2013 7:54:00 AM)
Magnificent imagery; painted complete scene of chance, love, death, eagerness...
Wonderful! (Report) Reply
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(March 26, 1874 – January 29, 1963)
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(16 August 1920 – 9 March 1994)
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- Go Down, Death, James Weldon Johnson
- Still I Rise, Maya Angelou
- The Road Not Taken, Robert Frost
- If, Rudyard Kipling
- Caged Bird, Maya Angelou
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text:
10 East 43rd Street
East Flatbush, New York, 11203
Commute to Downtown New York
Most errands can be accomplished on foot.
Transit is convenient for most trips.
Flat as a pancake, minimal bike lanes.
Score Details
10 East 43rd Street has a Walk Score of 89 out of 100. This location is Very Walkable so most errands can be accomplished on foot.
10 East 43rd Street is a 14 minute walk from the 2 7 Avenue Express and the 5 Lexington Avenue Express at the Winthrop St stop.
This location is in the East Flatbush neighborhood in New York. Nearby parks include Wingate Park, Wingate Park and Hawthorne Field.
Nearby schools include PS 235 Lenox School, St Catherine Of Genoa School and Battalion Christian Academy.
The closest grocery stores are Geo's Grocery, ELV Grocery and Ligia Grocery Store.
Nearby coffee shops include Dunkin' Donuts, Kings County Coffee Shop and Dunkin' Donuts. There are 69 restaurants within a 15 minute walk including Platinum Paradise, Fritz Jamacian & Amer Restaurant and Clarkson Restaurant.
10 East 43rd Street is near Rolf Henry Playground, Lincoln Terrace Park and Fidler-Wyckoff House Park.
There are minimal bike lanes and the terrain is flat as a pancake. 10 East 43rd Street is bikeable, there is some bike infrastructure.
Explore how far you can travel by car, bus, bike and foot from 10 East 43rd Street.
10 East 43rd Street has excellent transit which means transit is convenient for most trips. Car sharing is available from RelayRides and Zipcar.
Rail lines:
5 Lexington Avenue Express
0.6 mi
2 7 Avenue Express
0.6 mi
3 7 Avenue Express
1.0 mi
4 Lexington Avenue Express
1.0 mi
Q Broadway Express
1.2 mi
Bus lines:
B12 Lefferts Gardens - East New York
0.1 mi
B35 Brownsville - Sunset Park
0.3 mi
Car shares:
View all East Flatbush apartments on a map.
Popular apartment searches include hardwood floor, pool and furnished. View all New York apartments and rentals.
10 East 43rd Street is in the East Flatbush neighborhood. East Flatbush is the 105th most walkable neighborhood in New York with a neighborhood Walk Score of 89.
Moving to New York from another city? View our moving to New York guide.


text:
Iceland bus schedules and Maps
Winter schedule is from 4.Jan - 6.June 2015 for capital area
and 56,78,79 - starts 31.August - 1.may 2015
west and north, south area will start 14.Sept - 17.may 2015
New in 2015 is Suðurnes
and that starts on 4.Jan 2015
On this page you can find information about all bus schedules and public transportation around Iceland, in Reykjavík, towns and villages. In addition you can see the bus routes to the most popular tourist attractions.
Strætó - Public transportation in and around Iceland
Strætó is the public transportation in Iceland, in addition to buses in and around the capital area we have scheduled bus routes around major parts of Iceland.
See more information about popular bus destinations and places to visit in Iceland


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The second annual Turlock High Alumni Baseball game was held on Saturday, complete with a homerun derby and game between the Mendonca Maulers and Bettencourt Dreamers. In addition to the fun, there was also a touching moment as recently graduated Tyler Murphy threw out the first pitch.
American Medical Response is laying off 39 emergency medical technicians because of a lost contract for service with Doctors Medical Center.
The number of kids in Stanislaus County that consume sugary drinks on a daily basis has grown slightly, according to a newly released health survey.
Just in time for the pumpkin pie, Slow Food Great Valley Chapter is hosting its' Annual Harvest Dinner at the Larsa Banquet Hall between Turlock and Denair on Nov. 7. All-star chefs will work their magic with local ingredients presenting a full course meal featuring "Sweet Potatoes and More!"
Air Force Airman Tristan L. Jordan graduated from basic military training at Joint Base San Antonio-Lackland, San Antonio, Texas.
Deputy Andrew Mulgrew and Deputy Michael Maze have a passion for two things, competition pistol shooting and supporting wounded veterans. The two deputies were able to combine these passions at the recent Top Cop shooting contest.
Q: What got you started in the ministry?
The public will get their first opportunity to check out the inner workings of the new Public Safety Facility when the Turlock police and fire departments host their annual open house event Oct. 26.
It is not unusual for a student to take out a loan during college, but it is unusual for that student to use the loan to finance an event for other young adults such as local student Caleb Monticalvo has done.
Family and friends in Keyes joined together on Thursday for a fun-filled evening during the fourth annual Keyes Community Night.
Name: Sunrise Bakery
Turlock High science teacher Brian Campbell and his children Bryce, 9, Cadence, 6, and Mackenzie, 11, show their support for the Turlock Firefighters' pink t-shirt campaign to benefit Emanuel Cancer Center.
Year after year scholarships are awarded to students across the country to help them attend universities and further their careers. Turlock native Francine Denis and her family have helped Turlock students make college a reality through the Kelly Denis-Pierce Memorial Scholarship.
Sterling Ranch Park in Denair was cluttered with canines in costumes and exotic pets for the Walk 'N Wag event on Sunday.
The Great California ShakeOut earthquake drill is all set for Thursday morning and when the imagined "big one" hits at 10:17 a.m., officials are hoping everyone remembers to "Drop, Cover, and Hold On."
For anyone unaware the federal government charges a penalty for not carrying health insurance, Emanuel Medical Center is offering a helping hand.
Bad news just keeps on coming for local growers, as the Turlock Irrigation District Board of Directors considers implementing an even lower than the historically-low 20 inch water allotment in 2014, once the postponed irrigation season finally starts.
Deep fried food, thrilling amusement rides, and live music - all of these things come to mind when thinking of the Stanislaus County Fair. However for most people, the main event they look forward to year after year is livestock exhibitions.
The unemployment rate in Stanislaus County made a small rebound from the rise seen in January with a slight decline in February, according to the latest numbers from the Employment Development Department.
While going to the dentist is a matter of routine for many Americans, in Jamaica it's a luxury.
Table 26 will be opening its doors on Sunday and to say the new restaurant has transformed the former Sweet River Bar and Grill location would be an understatement.
Name of Business: Merafuentes Tae Kwon Do & Hapkido A Lee Brothers Academy
Dyeing eggs around Easter time is a tradition that is cherished by many families, but especially by the Gemperle family.
In an effort to avert more catastrophic water supply issues in the next year the California State Water Resources Control Board approved emergency measures on Tuesday to plan for the rough months ahead as the state enters into its fourth consecutive drought year.
In an effort to continue protecting threatened salmon and steelhead populations in three Sacramento River tributaries, the State Water Resources Control Board voted on Tuesday to re-adopt 2014 emergency regulation that will continue the curtailment of water diversions if minimum flows necessary for both species are not met.


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Now at 10 pm EST Monday nights!
John Alexander 🚀 241
March 23, 2015
Tonight we welcome John Alexander to the show! Make sure to check out his website if you would like to try to keep up with his adventures.
Listen online and continue reading ...
Charles Ostman 🚀 240
March 16, 2015
We are back from vacation and it's hard to get the engines started. However, we have Charles Ostman on tonight, and he will definitely clear away all the cobwebs. And heat up all the remaining snow! Join us at 10 PM EST, which is savings-time, not standard-time.
Listen online and continue reading ...
John Ilias 🚀 239
March 2, 2015
Tonight we will be speaking with Dr. J, host of Researcher On a Mission (ROAM), John Ilias, about last weeks incredible knock-down, take-no-prisoners show he produced with Bill and infamous debunker Robert Sheaffer. We will examine the thought processes that go into the whole debunking ritual. 🚀
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Mary Rodwell 🚀 238
February 23, 2015
Tonight we will be talking to Mary Rodwell, founder and principal of the Australian Close Encounter Resource Network (ACERN). Mary is a counsellor, hypnotherapist, Reiki Master, and researcher as well as the author of Awakening: How Extraterrestrial Contact Can Transform Your Life.
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Tim Swartz 🚀 237
February 16, 2015
I've been working on Tesla Illuminated, the first book to come out of the newly revived Filament Books ebook company and bookclub. We've asked Tim Swartz, author of The Lost Journals of Nikola Tesla and Men of Mystery with Tim Beckley, to give us more background on Nikola Tesla than the history books provide.
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Anders Nilsson 🚀 236
February 9, 2015
Do not fret! Even though we are interviewing the author of The Gentle Way of the Heart, I believe we can make the subject interesting to those nuts-and-bolts folks who want to keep real science in the picture. Have no fear and soften your hard, hard heart for tonight's show. You will feel better for it.
Scientist Anders Nilsson, PhD has been active in academia all his adult life. And, for just as many years, Nilsson has pursued an avid interest in spirituality. He has not followed any one spiritual school or tradition, nor has he studied with a guru, but instead listened to his internal voice and intuition to guide him. He has studied both ancient mystical traditions and the teachings from more contemporary spiritual masters. This blend of spiritual knowledge, when folded together with his scientific background, has formed a unique path to spiritual awakening that combines the mind and heart.
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John Liebert, William Scott 🚀 235
February 2, 2015
Join us tonight as we discuss the very difficult subject of traumatic stress. What does it do to the mind? How can it be tamed or caged or cured? Can it? John Liebert, MDCM psychiatrist and author William Scott discuss.
Meanwhile, from Wounded Minds: Understanding and Solving the Growing Menace of Post-Traumatic Stress Disorder, here is John's prologue to "The American Sniper": Double Homicide by fellow OIF veteran. Who was Eddie Routh?
💌 Check out the Waiting Wife project! 💌
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Skunk Works Revisited 234 🚀
January 26, 2015
In the course of writing the exciting and juicy Mickey Rooney biography, coauthors Bill and Rick have uncovered a very promising lead that may help uncover some of the truth about our government's perhaps and alleged involvement with extraterrestrials. Our guests tonight will be Tom Carey, Don Schmitt, Mickey's widow Jan and her sister Rona Riley, as well as Rick Lertzman.
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Story Rountable 🚀 233
January 19, 2015
Tonight we will be talking to three different guys, Anthony Caramanis, Noah Felice, and Chris Bones, with three very different stories about the paranormal. All situations begin to shred the boundaries of normal reality, and each situation is ongoing and very strange.
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Ardy Sixkiller Clarke 🚀 232
January 12, 2015
Join us tonight as we welcome Ardy Sixkiller Clarke into the thriving and growing Future Theater family. Ardy is a scholar and professor emeritus at Montana State University. Her newest book is Encounters With Star People: Untold Stories of American Indians.
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The International Society of Automation (www.isa.org) is a nonprofit professional association that sets the standard for those who apply engineering and technology to improve the management, safety, and cybersecurity of modern automation and control systems used across industry and critical infrastructure. Founded in 1945, ISA develops widely used global standards; certifies industry professionals; provides education and training; publishes books and technical articles; hosts conferences and exhibits; and provides networking and career development programs for its 36,000 members and 350,000 customers around the world.
ISA owns Automation.com, a leading online publisher of automation-related content, and is the founding sponsor of The Automation Federation (www.automationfederation.org), an association of non-profit organizations serving as "The Voice of Automation." Through a wholly owned subsidiary, ISA bridges the gap between standards and their implementation with the ISA Security Compliance Institute (www.isasecure.org) and the ISA Wireless Compliance Institute (www.isa100wci.org).
Membership Benefits
Full ISA Membership
Automation Affiliate Membership
Student Membership
Earned Membership Grades & Reciprocal Memberships
Saturday, 25 Apr 2015
Galveston, TX,
Sunday, 26 Apr - Thursday, 30 Apr, 2015
Galveston, TX,
Monday, 11 May - Thursday, 14 May, 2015
Huntsville, AL,
Tuesday, 19 May - Thursday, 21 May, 2015
New Orleans, LA,
Sunday, 07 Jun - Thursday, 11 Jun, 2015
Kansas City, MO,
ISA members have access to dozens of unique benefits. Update your member profile, set your communications preferences, find products and services that are right for you, and more – all from the convenience of your ISA website.
Featured Training: ISA Boot Camps
Featured White Paper: Workforce Development
Cover Story: Plant historians
Saturday, 25 Apr 2015
Hilton Hotel,
Sunday, 07 Jun - Thursday, 11 Jun, 2015
Kansas City Marriott Hotel,
Saturday, 13 Jun - Monday, 15 Jun, 2015
Raleigh Marriott City Center,
Thursday, 24 Sep 2015
ISA - International Society of Automation,
Monday, 09 Nov - Thursday, 12 Nov, 2015
Houston Marriott Westchase,
2015 ISA Power Industry Symposium features five acclaimed keynote speakers, an extensive technical program, training opportunities and more
Steve Mustard, industrial cybersecurity expert of the Automation Federation and ISA, selected as keynote speaker at CABA Forum
Automation Federation releases report commissioned by LOGIIC that studies the use of virtualization in IACS environments
Registration opens for 2015 ISA Leak Detection and Repair (LDAR)-Fugitive Emissions Symposium
New ISA book explores evolution of temperature pressure and flow technologies and more
Beamex is pleased to announce its cooperation with Mark Draghicescu Racing at Silverstone race circuit
ISA and Beamex to co host web seminar on how to avoid the pitfalls of calibration system implementation
Honeywell Named Best Industrial Wireless Provider at 2014 Asian Manufacturing Awards
Beamex launches Mikes Calibration Corner
FDT Sponsors Webinar on Changes Needed for Successful Asset Management
ISA has the resources and expert networks that you need – no matter what position you hold in our industries. Browse the products and services designed to meet the needs of these common industry roles:
ISA awarded me a 2013-2014 scholarship to help fund my education. I would not have been able to keep going to school if I had not received it. So, I want to give thanks to the many people of the ISA who work on securing the future of the organization just as the original founders had. ISA was and is forged and founded from true honesty and integrity that you will not find in to many other professions.
-Troy Riddle, Lee College
ISA's products and services are organized by technical topic – a selection of technologies, trends, and areas of focus that are relevant to your on-the-job performance:
Author: Greg McMillan and Hunter Vegas
Copyright 2013
Length: 250 pages
Do you want to:
While this book cannot guarantee the above results, the content should provide an automation engineer with a proven path to career and technical success. So much of the automation field depends upon experience, and many feel that experience can only come with gray, thinning hair and lots of wrinkles.
However, with this book, we invite you to take full advantage of two lifetimes of hard-fought lessons learned and to avoid many of the technical and career pitfalls made by the authors.With 60 years of automation and control experience, we—Greg McMillan and Hunter Vegas—have installed hundreds of millions of dollars' worth of equipment and managed thousands of projects. We have witnessed (and occasionally committed) a whole host of blunders, and we have the scars and gray hair to prove it. Fortunately for you, we are willing to share what works and what doesn't work so that the next generation can benefit.
So… save your hair! Avoid premature aging! And most importantly, save yourself a whole lot of pain and suffering! We sure wish we'd had a book like this when we were getting started.


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|Named Person:
|Henry Festing Jones; Mansfield Forbes; Daisy Ashford; A T Bartholomew; William Osler, Sir; Charles Sayle; Francis Jenkinson; Arthur Quiller-Couch; A E Housman; S C Roberts; A T Bartholomew; Mansfield Forbes; A E Housman; Francis Jenkinson; Henry Festing Jones; William Osler, Sir; Arthur Quiller-Couch; S C Roberts; Charles Sayle
|Material Type:
|Document Type:
|Book, Archival Material
|All Authors / Contributors:
Bruce Rogers; Henry Watson Kent; Ray Nash
|OCLC Number:
|Copy with revisions and deletions.
Original letter written May 3, 1919.
Written from Park Side, Cambridge.
Part of a collection of autograph and typed letters signed and revised copies of letters to Henry Watson Kent. Items in this collection have been described individually in separate catalog records; see collection-level record for more information.
|1 item (6 p.) ; 25.7-27.2 cm.
Recalling a "hilarious evening we had recently" involving Henry Festing Jones, Manny Forbes, and the reading aloud of Daisy Ashford's "Young Visiters"; describing his friend A.T. Bartholomew and early evening bike rides; expressing his delight at having been invited to lunch with Sir William Osler, Charles Sayle, and F.J.H. Jenkinson, and describing a walk they took during which Jenkinson fell behind collecting bits of foil to "[help] the war effort"; describing a lecture series given by Sir Arthur Quiller-Couch at Jesus College and mentioning that A.E. Housman was in the audience recently; mentioning having had dinner with Capt. S.C. Roberts; discussing his sailing adventures; recalling having met a Dr. Bull who was an expert on sheep ticks.
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Similar Items
Related Subjects:(12)
- Jones, Henry Festing, -- 1851-1928.
- Forbes, Mansfield.
- Ashford, Daisy. -- Young visiters.
- Bartholomew, A. T. -- (Augustus Theodore), -- 1882-1933.
- Osler, William, -- Sir, -- 1849-1919.
- Sayle, Charles, -- 1864-1924.
- Jenkinson, Francis, -- 1853-1923.
- Quiller-Couch, Arthur, -- 1863-1944.
- Housman, A. E. -- (Alfred Edward), -- 1859-1936.
- Roberts, S. C. -- (Sydney Castle), -- 1887-1966.
- 1950.
- Young visiters (Ashford, Daisy)


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BKE Sequin Fireball Necklace
SALE $3.50 was $14.00 Item #10414MN56759
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- Heavily discounted item: may have slight imperfections, flaws, fading or discoloration. No returns, exchanges or free alterations.
- Feather and chain necklace
- Made in China.
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We changed our page. Tell us what you think.
- Length measures 31 1/2".


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"I had so much fun hosting the Billboard Music Awards last year and I can't wait to be back!" said Ludacris. read more ….Read More Via:: THE HOLLYWOOD REPORTER – MUSIC
Corner Office: YouTube Music Chief Vivien Lewit on Reimagining Its Awards and Helping Women Get Ahead in Tech Billboard – News
The first Youtube Music Awards, held Nov. ….Read More Via:: Billboard – News
First Look At Walking Dead Spin-Off Empire Magazine
Welcome to Zombieland, California As Walking Dead creator and exec-producer Robert Kirkman revealed on Twitter, the show's planned spin-off now has a name – Fear The Walking Dead – and it now has a first teaser too. This trailer will air as The Walking Dead gets its season five climax next ….Read More Via:: EMPIRE Read more
DJ Michelle Pesce Launches Nona Entertainment (Exclusive) The Hollywood Reporter - Music
The new firm will represent DJs, including booking private events read more ….Read More Via:: THE HOLLYWOOD REPORTER – MUSIC
Apple CEO Tim Cook Blasts Anti-Gay 'Religious Freedom' Legislation Billboard – News
Apple CEO Tim Cook said that so-called "religious objection" legislation being introduced in a number of states is dangerous and bad for business…. ….Read More Via:: Billboard – News
American Greetings Hopes to Provoke a Groundswell of Gratitude With the ThankList Adweek – Adfreak
American Greetings goes all-in with ThankList, an immersive multimedia experience from Mullen that encourages people to thank those who've made an impact on their lives. Two-time Oscar winner Barbara Kopple (for the documentaries Harlan County USA and American Dream) created five short films through production ….Read More Via:: ADWEEK – AdFreak
Sacha Baron Cohen Isn't Doing That Freddie Mercury Biopic After All THE PLAYLIST
Perhaps it was too good to be true. Over the weekend news emerged that Sacha Baron Cohen was to write, produce, direct and star in the forever developing Freddie Mercury biopic. It was a surprising turn of events for the once-attached actor, and while there was even a source quote ….Read More Via:: THE PLAYLIST
Mark Strong Heads For Jadotville Empire Magazine
He's joining Jamie Dornan in the war thriller Mark Strong, erstwhile Floating Head of this parish and guest of this past weekend's Jameson Empire Awards, has added another film to his typically busy roster. He's set to co-star with Jamie Dornan in the ….Read More Via:: EMPIRE MAGAZINE
Fox Searclight Acquires Davis Guggenheim's Malala Yousafzai Doc Thompson on Hollywood
Fox Searchlight has acquired worldwide rights, except for France and other French-speaking territories, to the documentary "He Named Me Malala." Directed by Davis Guggenheim, who won an Oscar for "An Inconvenient Truth" and also directed "Waiting for Superman," the film is slated for 2015 release. The documentary, produced by ….Read More Via:: THOMPSON on HOLLYWOOD
Adam West And Burt Ward Announce New Batman Animated Film Empire Magazine
Holy team reunion, Batman! They might have been off our screens as the dynamic duo since their Batman series ended in 1968, but you can't keep Adam West and Burt Ward away from the Caped Crusader and his faithful sidekick. They announced at a Batman panel as part of the Mad ….Read More Via:: EMPIRE Read more


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Partial soffit?
We are adding a hood as part of our kitchen remodel. The contractor originally thought that he would need to run the vent through a soffit, so the plans for the kitchen included a soffit on top of the cabinets on one side, with the cabinets on the other side going all the way to the ceiling. Now it turns out that there is enough room in the ceiling to run the vent, so a soffit is not necessary. If we eliminate the soffit entirely, the cabinets on one side will have 8+ inches of open space on top. We can't run the cabinets on that side all the way to the ceiling because of a staircase (it would prevent the cabinet doors from opening fully). So the question is should we leave open space on top of the two cabinets, or should we have a partial soffit built on top of those two cabinets? I kind of like the idea of a partial soffit--I think it will be more symmetrical with the facing cabinets and I don't want to have to clean on top of cabinets. But I wanted to see what the experts here have to say before we make a final decision. Thanks!
I would do whatever looks natural and symmetrical
Sometimes this means doing a soffit. If you don't need the extra 8 inches on the other side, it may look more symmetrical and natural to do the same height of cabinets on both sides and the small soffit on both sides.
It's hard to say for sure without seeing the actual plans.
Soffits are often needed on the projects I work on because the houses are mostly row houses, and ducts need to be run against the joist direction. It seems counter intuitive but sometimes it makes sense to have more length to the overall soffit to "connect" it to something or a soffit where you don't technically need it for balance.
A planned soffit can disappear better sometimes, even if it's bigger. than an incomplete "bump" somewhere that the eyes go to and tell you that there is a pipe or duct that needed to be covered up.
We wanted to get rid of all of our soffits, but wound up having to keep one out of three. You can check out the final result in my kitchen pics. The soffit is "disguised" as best as possible on the wall above the sink. It houses major plumbing for the upstairs bathrooms. We ordered the cabinets before we knew the deal, so we had to figure out what would look best. Good luck!
Here is a link that might be useful: Dusty's kitchen