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The desert oasis of Khotan was long a major hub on the Silk Road. Made famous by its rug weaving and trading posts, the bustling center became a multicultural mix of East Asian and Middle Eastern goods, beliefs and, of course, designs. Khotan-style rugs are, like their native land, a blend of influences from across the Asian continent. Fittingly, this floor rug has been patched together from traditional, overdyed rugs.
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Lost Girls' Borneo Gear Guide
How do the Lost Girls, minimalists by no stretch of the imagination (we believe in lipstick!), pack light without sacrificing creature comforts? See what we couldn't live without on our Borneo trip.
borneo-gear-guide_ss_001Packing proved to be a challenge for our Borneo trip, as we'd be away for roughly three weeks and doing everything from diving off the island of Sipadan to climbing to the top of Mount Kinabalu. Moreover, we didn't want to risk losing checked luggage with three long flights, a few bumpy bus rides, and a boat journey, so we had to fit everything into a carry-on. 960 1280
Rolling LuggageNo longer twenty-something backpackers, we want luggage that is compact, stylish, and that can also roll. We're big fans of Eagle Creek's line of travel accessories, so we opted for the Switchback Max 22. rolling convertible backpack.
The red clay color stands out from the sea of black bags at the airport, and it even has a zip-off backpack complete with laptop sleeve (we couldn't leave behind our iPads and Kindles!). 960 1280
An Organizational SystemHolly tested out the Hoboroll, an organizer with five compartments that has drawstring end closures and compression straps to minimize bulk. "It saved me from having to dig around my luggage for my clothes, separated dirty garments from clean, and could even be used as a pillow on the plane!" says Holly.
There's also a tool loop making it possible for hikers to clip onto their daypacks, and for minimalists to use as their main bag. 960 1280


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Copper Fungicide Dangerous
Hey guys,
does anyone have info on copper fungicide? Is it harmful/dangerous to humans? I don't know why every time I spray (and I wear long sleeve, long pants and shoes and cover my face) I feel like I might be poisoning myself....
any words of wisdom?
I don't know about copper fungicide being poisonous.I always use a respirator when I'm spraying any chemicals..Most fungicides tell on the back label to use a mask when spraying it,and try to spray downwind.I wear long pants and a long sleeve shirt also.I don't want to take any chances of poisoning myself.
Yes it is poisonous if you consume it. It is good advise to cover your hands and arms when using it. I have had it on my hands and I just washed it off and all was fine. I personally would use another fungicide unless you really need to use copper. Copper is poisonous to birds and animals as well.


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Impact Of Retrovirals On Body
Here's a taste of what TheBody.com has to offer on this topic:
Get the Facts
An Overview of Retrovir (Zidovudine, AZT)...Recommended Daily Dose The recommended dose of zidovudine is 600 mg a day (either 300 mg twice a day or 200 mg three times a day). The recommended dose in pediatric patients aged 4 weeks to 18 years should be determined by body weight or body surface area. Dosing by weight is as follows: For pediatric patients who weigh from 4 kg to less than 9 kg, a total daily dose of 24 mg/kg should be given in equal doses twice or three times daily. For...
Ask the Experts
How do additional deal with hiv bodyDr. BobI am recently diagnosed with hiv, and will be starting medication very soon. I am currently finishing off my masters in organic chemistry (biochem undergrad) and am very in tune to the workings of the body. As such have been doing a lot of...
Response from Robert J. Frascino, M.D.
The Robert James Frascino AIDS Foundation...cruciferous vegetables). Some phytochemicals work as antioxidants, but others appear to have different mechanisms of action. How HIV Impacts Nutrition ... and Vice Versa In the early years of the epidemic, healthcare providers soon learned that... Read more »
PLEASE HELP A SCARED MOM!Dr. Bob:Hello! I am writing because I am terrified, emotionally drained and a total wreck. Almost 4 weeks ago I may have injured myself with a dart at a carnival and 2 weeks to the VERY DAY after that I noticed a lump in my groin (well, actually I...
Response from Robert J. Frascino, M.D.
The Robert James Frascino AIDS Foundation...myself with a dart at a carnival" is not a recognized risk for HIV transmission. HIV doesn't live very long at all outside the body. Therefore the chance that someone else was as klutzy as you with the carnival dart and that that person was HIV... Read more »
Acute Retroviral SyndromeThe Body: Rick Sowadsky M.S.P.H., C.D.S, Answers to Safe Sex QuestionsI recently found out a friend is HIV positive. He has not been sexually active for about two years( so he says ). He recently had flu like symptoms and decided to go to the doctor. Thats when he found out he had HIV. Lets say he is telling the truth...
Response from Rick Sowadsky, M.P.H.
Nevada State Health Division AIDS Program...HIV. Of course, your friend may have had the flu itself, oranother type of infection. However Acute Viral Syndrome is the body'sinitial response against infection, and does NOT occur months or years afterinfection.For more information about the... Read more »
Acute Retroviral SyndromeThe Body: Rick Sowadsky M.S.P.H., C.D.S, Answers to Safe Sex QuestionsWhen a person starts suffering from Acute Retroviral Syndrome, is it usually severe or mild "flu" like symptoms? My question is do the majority suffer from severe or mild flu like symptoms?
Response from Rick Sowadsky, M.P.H.
Nevada State Health Division AIDS Program...weeks after infection, some people with HIV (up to 70%)show symptoms due to "Acute Viral Syndrome." This occurs during your bodiesinitial response against the virus. During this time, a person may showsymptoms that look exactly like the flu... Read more »
Body Shape Changes Dramatically Impact the Self-Esteem of HIV-Positive People...defined. How can we convince insurance companies that this is not only a cosmetic issue? That this is a clinical issue that impacts quality of life and can result in depression, anxiety and even suicidal thoughts. It even impacts adherence; some... Read more »
Surprising Changes in Body Fat With Darunavir Monotherapy...people who tended to not gain belly fat. The regimens that volunteers took prior to joining Monoi did not apparently have any impact on subsequent changes in body composition during the study. Putting It in Perspective Monoi is ongoing and... Read more »
The 5th Conference on Retroviruses and Opportunistic Infections...Factors Associated with Survival in the Women's Interagency HIV Study Covered by the Seattle Treatment Education Project The Impact of HAART on Rates and Types of Hospitalizations: Abstracts 179-184, 198, 205-206, 257 Summaries by Kent... Read more »
Retrovir...to most as AZT, with a generic form available in the U.S.) was the first antiretroviral developed and has had a significant impact on the course of HIV infection. Historically, AZT development has served as an example of a highly successful... Read more »
Connect With Others
Sindrome Retroviral Agudo...
Posted by Anonymous, 2 Replies...debajo de la amigdala y otro ms pequeo ms abajo, cerca de la clavcula. Estoy aterrorizado. Que hago??? Si no fuera una sindorme retroviral agudo, a que se pueden deber esos ganglios. Es comn? Read more »
Acute Retroviral Infection
Posted by DDS, 1 ReplyI was just diagnosed last week. My HIV doctor thinks that I am experiencing, based on my symptoms, and Acute Retrovirial Infection. He and I believe that I am very recently infected (July). He said there are some new treatment paths for people... Read more »
Posted by Anonymous, 3 Replies...covering the childs entire body. No problems with epivir or retrovir and rashes. We are so scared for this child. It has impacted the remaining days of school. What can be done to sooth the skin? Read more »
Mary Fisher story
Posted by Anonymous, 1 Reply...are being tested. Too often researchers talk about the potency of a drug against a disease without taking into account the impact of side effects on the patient. In a study of health care workers who were exposed to the virus in the workplace... Read more »
Resource Centers
Guides for People With HIV


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Are you Akira Yamamoto?Claim your profile
Publications (99)181.35 Total impact
[Show abstract] [Hide abstract]
ABSTRACT: The purpose was to compare capability of fluorine-18 fluorodeoxyglucose (FDG)-PET and thallium-201 (Tl)-SPECT for grading meningioma.This retrospective study was conducted as a case-control study under approval by the institutional review board. In the hospital information system, 67 patients (22 men and 45 women) who had both FDG-PET and Tl-SPECT preoperative examinations were found with histopathologic diagnosis of meningioma. The maximum FDG uptake values of the tumors were measured, and they were standardized to the whole body (SUVmax) and normalized as gray matter ratio (SUVRmax). Mean and maximum Tl uptake ratios (TURmean and TURmax, respectively) of the tumors were measured and normalized as ratios to those of the contralateral normal brain. Receiver-operating characteristic curve analyses of the 4 indexes were conducted for differentiation between low- and high-grade meningiomas, and areas under the curves (AUCs) were compared. Correlation coefficients were calculated between these indexes and Ki-67.Fifty-six meningiomas were classified as grade I (low grade), and 11 were grade II or III (high grade). In all 4 indexes, a significant difference was observed between low- and high-grade meningiomas (P < 0.05). AUCs were 0.817 (SUVmax), 0.781 (SUVRmax), 0.810 (TURmean), and 0.831 (TURmax), and no significant difference was observed among the indexes. Their sensitivity and specificity were 72.7% to 90.9% and 71.4% to 87.5%, respectively. Correlation of the 4 indexes to Ki-67 was statistically significant, but coefficients were relatively low (0.273-0.355).Tl-SPECT, which can be used at hospitals without a cyclotron or an FDG distribution network, has high diagnostic capability of meningioma grades comparable to FDG-PET.
Article: Grading glial tumors with amide proton transfer MR imaging: different analytical approaches[Show abstract] [Hide abstract]
ABSTRACT: Amide proton transfer (APT) magnetic resonance imaging is gaining attention for its capability for grading glial tumors. Usually, a representative slice is analyzed. Different definitions of tumor areas have been employed in previous studies. We hypothesized that the accuracy of APT imaging for brain tumor grading may depend upon the analytical methodology used, such as selection of regions of interest (ROIs), single or multiple tumor slices, and whether or not there is normalization to the contralateral white matter. This study was approved by the institutional review board, and written informed consent was waived. Twenty-six patients with histologically proven glial tumors underwent preoperative APT imaging with a three-dimensional gradient-echo sequence. Two neuroradiologists independently analyzed APT asymmetry (APTasym) images by placing ROIs on both a single representative slice (RS) and all slices including tumor (i.e. whole tumor: WT). ROIs indicating tumor extent were separately defined on both FLAIR and, if applicable, contrast-enhanced T1-weighted images (CE-T1WI), yielding four mean APTasym values (RS-FLAIR, WT-FLAIR, RS-CE-T1WI, and WT-CE-T1WI). The maximum values were also measured using small ROIs, and their differences among grades were evaluated. Receiver operating characteristic (ROC) curve analysis was also conducted on mean and maximum values. Intra-class correlation coefficients for inter-observer agreement were excellent. Significant differences were observed between high- and low-grade gliomas for all five methods (P < 0.01). ROC curve analysis found no statistically significant difference among them. This study clarifies that single-slice APT analysis is robust despite tumor heterogeneity, and can grade glial tumors with or without the use of contrast material.Journal of Neuro-Oncology 01/2015; DOI:10.1007/s11060-014-1715-8 · 3.12 Impact Factor
Article: Primary central nervous system lymphoma and glioblastoma: differentiation using dynamic susceptibility-contrast perfusion-weighted imaging, diffusion-weighted imaging, and (18)F-fluorodeoxyglucose positron emission tomography.[Show abstract] [Hide abstract]
ABSTRACT: The objective was to evaluate diagnostic performance of dynamic susceptibility-contrast perfusion-weighted imaging, diffusion-weighted imaging, and (18)F-fluorodeoxyglucose positron emission tomography in differentiating primary central nervous system lymphoma (PCNSL) and glioblastoma. Twenty-three glioblastomas and 11 PCNSLs were analyzed with uncorrected cerebral blood volume (CBV) ratio, fifth percentile value of cumulative apparent diffusion coefficient histogram (ADC5%), and maximum standardized uptake value (SUVmax) using regions of interest created semiautomatically on enhancing areas. Uncorrected CBV ratio was highly capable of differentiating PCNSL from glioblastoma, as well as SUVmax and ADC5%. Uncorrected CBV ratio demonstrates high diagnostic performance comparable to SUVmax. Copyright © 2014 Elsevier Inc. All rights reserved.Clinical Imaging 12/2014; DOI:10.1016/j.clinimag.2014.12.002 · 0.60 Impact Factor
Article: Effective palliative radiofrequency ablation for tumors causing pain, numbness and motor function disorders: case series.[Show abstract] [Hide abstract]
ABSTRACT: We present a case series of a palliative radiofrequency ablation (RFA) for the tumors that lead to the resolution of pain and motor function disorders. RFA is widely used on tumors in various organs and often reported in good outcome. There are some reports that RFA was performed as a palliative treatment but a few reports of RFA that performed for lung tumor as a palliative treatment. This case series includes two cases, palliative RFA for a sacrum and a lung tumor. The results of this case series presented that a palliative RFA is effective in improving the symptoms of patients.BMC Research Notes 10/2014; 7(1):765. DOI:10.1186/1756-0500-7-765
Article: Combination Radiofrequency Ablation and Local Injection of the Immunostimulant Bacillus Calmette-Guérin Induces Antitumor Immunity in the Lung and at a Distant VX2 Tumor in a Rabbit Model.[Show abstract] [Hide abstract]
ABSTRACT: To evaluate whether the combination of radiofrequency (RF) ablation and local injection of the immunostimulant Mycobacterium bovis bacillus Calmette-Guérin (BCG) induces systemic antitumor immunity. Japanese White rabbits with lung and auricle VX2 tumors were randomized into three groups: control (n = 8; no treatment), RF ablation only (n = 8; RF ablation to the lung tumor), and RF ablation with local BCG injection into the lung tumor (n = 8). Treatments were performed 1 week after tumor implantation. Survival was evaluated with Kaplan-Meier method and log-rank test. Weekly mean volume and specific growth rate (SGR) of auricle tumors were calculated, and comparisons were made by Mann-Whitney test. Median survival of control, RF-only, and RF/BCG groups were 23, 41.5, and 103.5 days, respectively. Survival was significantly prolonged in the RF-only and RF/BCG groups compared with the control group (P = .034 and P =.003, respectively), but no significant difference was found between the RF-only and RF/BCG groups (P = .279). Only in the RF/BCG group was mean auricle tumor volume decreased 5 weeks after implantation. No significant difference in SGR was found between the control and RF-only groups (P = .959), but SGR in the RF/BCG group was significantly lower than in the control group (P = .005). The combination of RF ablation and local injection of BCG resulted in distant tumor suppression compared with the control group, whereas RF ablation alone did not produce this effect. Therefore, the combination of RF ablation and local injection of BCG may induce systemic antitumor immunity. Copyright © 2014 SIR. Published by Elsevier Inc. All rights reserved.Journal of vascular and interventional radiology: JVIR 10/2014; DOI:10.1016/j.jvir.2014.09.002 · 1.81 Impact Factor
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ABSTRACT: The aim of this study is to investigate the relationship between abnormal retropharyngeal lymph nodes (RPLNs) and sinonasal malignancies among adults.Neuroradiology 09/2014; DOI:10.1007/s00234-014-1428-x · 2.37 Impact Factor
Conference Paper: Fetal pituitary hyperintensity on T1-weighted images: Appearance in less than 21 weeks gestational age fetuses.International Congress of Radiology ICR2014, Dubai, UAE; 09/2014
Article: Usefulness of CT volumetry for gastric varix before balloon-occluded retrograde transvenous obliteration.[Show abstract] [Hide abstract]
ABSTRACT: To evaluate the feasibility of gastric variceal (GV) volumetry using computed tomography (CT) images taken before balloon-occluded retrograde transvenous obliteration (B-RTO) and to assess its correlation with the actual amount of 5% ethanolamine oleate and iodinated contrast medium (EOI) injected in B-RTO. Forty-seven consecutive patients with GV underwent B-RTO of the gastrorenal shunt. GV volume was measured with preoperative CT images by three radiologists. Statistical significance was examined by intraclass correlation coefficient (ICC) for concordance among three radiologists and by Pearson correlation test for correlation between GV volume and the amount of 5% EOI injected. GV volumes measured by three radiologists significantly correlated with each other (ICC=0.959). Combining all patients and all measurements, the mean GV volume and the mean amount of 5% EOI were 27.02±16.67cm3 and 28.72±17.72mL, respectively. There was a significant correlation between GV volume, calculated as a mean of the three values measured by the three radiologists, and the amount of EOI (r2=0.706, p<0.001). GV volume measured on CT showed a significant correlation with the amount of 5% EOI injected. CT volumetry of GV has the potential to determine an amount of the sclerosing agent to be injected in B-RTO.Hepato-gastroenterology 09/2014; 61(134):1806-11. · 0.91 Impact Factor
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ABSTRACT: Objective: We qualitatively evaluated the differences among susceptibility-weighted (SWI), magnitude (MAG), and high pass filtered phase (PHA) images in depicting inter-lobar differences in the appearance of the signal of the corticomedullary junction (CMJ). We conducted quantitative evaluation to validate the qualitative results. Materials and Methods: We obtained SWI images from 25 preoperative brain tumor patients (12 men, 13 women, aged 19 to 82 years, mean, 52 years). Two trained neuro-radiologists evaluated MAG, PHA, and SWI images. Qualitative evaluation of the CMJ signal and quantitative calculation of the relative signal ratio (RSR) percentages between the CMJ and deep white matter (WM) were conducted at 3 different slice levels of the brain independently for 4 different lobes (frontal, parietal, temporal, and occipital) and com-pared among MAG, PHA, and SWI. The extent of the area of the CMJ signal was graded on a 4-point scale (Grade 3, >75%; Grade 2, 50 to 75%; Grade 1, 25 to 50%; Grade 0, <25%). Data were statistically analyzed using a nonparametric Friedman test. Results: The Kappa coefficients between the qualitative and quantitative grades were 0.002 for MAG, 0.0047 for PHA, and 0.050 for SWI. Qualitatively, on the PHA images and SWI, grades of the occipital lobes were significantly higher than those of the other lobes (P < 0.005). Quantitatively, PHA images showed statistically significant interlobar differences in RSR percentage values of the CMJ (P = 0.025). Conclusion: Qualitatively, the appearance of the CMJ differed significantly among the different lobes of the brain on SWI and underlying PHA images but not on MAG images. Quantitatively, only PHA images showed significant interlobar differences in the RSR. PHA images are most sensitive to the CMJ signal contrast due to local paramagnetic iron content.Magnetic Resonance in Medical Sciences 08/2014; DOI:10.2463/mrms.2013-0108 · 1.04 Impact Factor
Article: 3D dynamic pituitary MR imaging with CAIPIRINHA: Initial experience and comparison with 2D dynamic MR imaging[Show abstract] [Hide abstract]
ABSTRACT: Objectives: To evaluate the validity of 3D dynamic pituitary MR imaging with controlled alia sing in parallel imaging results in higher acceleration (CAIPIRINHA), with special emphasis on demarcation of pituitary posterior lobe and stalk. Methods: Participants comprised 32 patients who underwent dynamic pituitary MR imaging due to pituitary or parasellar lesions. 3D dynamic MR with CAIPIRINHA was performed at 3T with 20-s-interval, precontrast, 1st to 5th dynamic images. Normalized values and enhanced ratios (dynamic postcontrast image values divided by precontrast ones) were compared between 3D and 2D dynamic MR imaging for patients with visual identification of posterior lobe and stalk. Results: In 3D, stalk was identified in 29 patients and unidentified in 3, and posterior lobe was identified in 28 and unidentified in 4. In 2D, stalk was identified in 26 patients and unidentified in 6 patients, and posterior lobe was identified in 15 and unidentified in 17. Normalized values of pituitary posterior lobe and stalk were higher in 3D than 2D (P<0.001). No significant difference in enhancement ratio was seen between 3D and 2D. Conclusions: 3D dynamic pituitary MR provided better identification and higher normalized values of pituitary posterior lobe and stalk than 2D.European Journal of Radiology 07/2014; 83(10). DOI:10.1016/j.ejrad.2014.06.018 · 2.16 Impact Factor
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ABSTRACT: Oxygen causes an increase in the longitudinal relaxation rate of tissues through its T1-shortening effect owing to its paramagnetic properties. Due to such effects, MRI has been used to study oxygen-related signal intensity changes in various body parts including cerebrospinal fluid (CSF) space. Oxygen enhancement of CSF has been mainly studied using MRI sequences with relatively longer time resolution such as FLAIR, and T1 value calculation. In this study, fifteen healthy volunteers were scanned using fast advanced spin echo MRI sequence with and without inversion recovery pulse in order to dynamically track oxygen enhancement of CSF. We also focused on the differences of oxygen enhancement at sulcal and ventricular CSF. Our results revealed that CSF signal after administration of oxygen shows rapid signal increase in both sulcal CSF and ventricular CSF on both sequences, with statistically significant predominant increase in sulcal CSF compared with ventricular CSF. CSF is traditionally thought to mainly form from the choroid plexus in the ventricles and is absorbed at the arachnoid villi, however, it is also believed that cerebral arterioles contribute to the production and absorption of CSF, and controversy remains in terms of the precise mechanism. Our results demonstrated rapid oxygen enhancement in sulcal CSF, which may suggest inhaled oxygen may diffuse into sulcal CSF space rapidly probably due to the abundance of pial arterioles on the brain sulci.PLoS ONE 06/2014; 9(6):e100723. DOI:10.1371/journal.pone.0100723 · 3.53 Impact FactorThis article is viewable in ResearchGate's enriched formatRG Format enables you to read in context with side-by-side figures, citations, and feedback from experts in your field.
Article: Visualization of Lenticulostriate Arteries at 3T: Optimization of Slice-selective Off-resonance Sinc Pulse prepared TOF-MRA and Its Comparison with Flow-sensitive Black-blood MRA[Show abstract] [Hide abstract]
ABSTRACT: To optimize visualization of lenticulostriate artery (LSA) by time-of-flight (TOF) magnetic resonance angiography (MRA) with slice-selective off-resonance sinc (SORS) saturation transfer contrast pulses and to compare capability of optimal TOF-MRA and flow-sensitive black-blood (FSBB) MRA to visualize the LSA at 3T. This study was approved by the local ethics committee, and written informed consent was obtained from all the subjects. TOF-MRA was optimized in 20 subjects by comparing SORS pulses of different flip angles: 0, 400°, and 750°. Numbers of LSAs were counted. The optimal TOF-MRA was compared to FSBB-MRA in 21 subjects. Images were evaluated by the numbers and length of visualized LSAs. LSAs were significantly more visualized in TOF-MRA with SORS pulses of 400° than others (P < .003). When the optimal TOF-MRA was compared to FSBB-MRA, the visualization of LSA using FSBB (mean branch numbers 11.1, 95% confidence interval (CI) 10.0-12.1; mean total length 236 mm, 95% CI 210-263 mm) was significantly better than using TOF (4.7, 95% CI 4.1-5.3; 78 mm, 95% CI 67-89 mm) for both numbers and length of the LSA (P < .0001). LSA visualization was best with 400° SORS pulses for TOF-MRA but FSBB-MRA was better than TOF-MRA, which indicates its clinical potential to investigate the LSA on a 3T magnetic resonance imaging.Academic radiology 06/2014; 21(6):812-6. DOI:10.1016/j.acra.2014.03.007 · 2.09 Impact Factor
Article: Diffusion tensor imaging analysis of optic radiation using readout-segmented echo-planar imaging[Show abstract] [Hide abstract]
ABSTRACT: To investigate the diffusion tensor imaging parameters of the optic radiation and surrounding structures using the high-resolution readout-segmented diffusion tensor imaging method. Coronal readout-segmented diffusion tensor images were acquired in 15 healthy volunteers. On three slices of each image, eigenvalue 1, fractional anisotropy, radial diffusivity, apparent diffusion coefficient, and signal intensity on T2-weighted images were measured in the lateral inferior longitudinal fasciculus, external and internal layers of the optic radiation, and the tapetum within regions of interest delineated by two independent observers. Profile curve analysis of regions of interest across the optic radiation and surrounding structures was performed for a representative typical case. Significant differences in fractional anisotropy, radial diffusivity and apparent diffusion coefficient were observed between external and internal layers of the optic radiation, while there was no significant difference in eigenvalue 1. In fractional anisotropy maps, two low signal bands were observed between the inferior longitudinal fasciculus, the optic radiation and the tapetum. Profile curve analysis showed a minimum on the fractional anisotropy and eigenvalue 1 images and a maximum in the radial diffusivity image. Readout-segmented diffusion tensor imaging revealed significant differences in the diffusion tensor imaging parameters between internal and external layers of the optic radiation.Anatomia Clinica 04/2014; 36(10). DOI:10.1007/s00276-014-1299-1 · 1.33 Impact Factor
Article: Neointimal hyperplasia after stent placement across size-discrepant vessels in an animal study.[Show abstract] [Hide abstract]
ABSTRACT: To examine differences in neointimal hyperplasia (NIH) after placing a self-expanding (SE) stent across size-discrepant vessels. The subjects were 6 beagles, and the target vessels were the abdominal aorta and the external iliac artery (EIA). A nitinol SE stent was placed which was normal-sized in the aorta and oversized in the EIA. Angiography and intravascular ultrasound (IVUS) were performed immediately and after 1 and 3 months; histopathologic examinations were then performed. Furthermore, the chronic outward force (COF) on the same type of stent was investigated in vitro. On IVUS, thickened intima was seen on the EIA at 1 month (5.1 ± 4.2 mm(2)) and at 3 months (7.8 ± 2.5 mm(2)). For the aorta, thickening of the intima was negligible at any time. Histopathologically, the percentage of the vessel obliterated by NIH was significantly greater on the iliac side than on the aortic side (33.2 ± 10.4 vs. 13.4 ± 4.4 %). The COF exerted when stent diameter reached that of the EIA and the aorta was 0.73 and 0.17 N/mm(2), respectively. When a non-tapered stent is placed in vessels with a large discrepancy in diameter, attention must be paid to increased NIH in the oversized side.Japanese journal of radiology 04/2014; 32(6). DOI:10.1007/s11604-014-0311-3 · 0.73 Impact Factor
Article: Quantitative imaging values of CT, MR, and FDG-PET to differentiate pineal parenchymal tumors and germinomas: are they useful?[Show abstract] [Hide abstract]
ABSTRACT: Quantitative values of CT attenuation, apparent diffusion coefficient (ADC), and standardized uptake value (SUV) were investigated for differentiation between pineal parenchymal tumors (PPTs) and germinomas. Differences in age, sex, and calcification pattern were also evaluated. Twenty-three patients with PPTs and germinomas in 20 years were retrospectively enrolled under the approval of the institutional review board. CT attenuation, ADC, and SUV (20, 13, and 10 patients, respectively) were statistically compared between the two tumors. Differences in sex and patterns of calcification ("exploded" or "engulfed") were also examined. Mean patient ages were compared among three groups of pineoblastoma, pineal parenchymal tumor of intermediate differentiation, (PPTID) and pineocytoma and germinoma. None of the quantitative values of CT attenuation, ADC, and SUV showed significant differences between PPTs and germinomas (p > .05). However, there was a significant difference in age (p < .05) among the three groups of pineoblastoma (mean age ± standard deviation 7.0 ± 8.7 years), PPTID, and pineocytoma (53.7 ± 11.4 years) and germinoma (19.1 ± 8.1 years). Sex also showed significant differences between PPTs and germinomas (p = .039). Exploded pattern of calcification was found in 9 of 11 PPT patients and engulfed pattern in 7 of 9 patients with germinomas. No reverse pattern was observed, and the patterns of calcification were considered highly specific of tumor types. None of the quantitative imaging values could differentiate PPTs from germinomas. Age, sex, and calcification patterns were confirmed useful in differentiating these tumors to some degree.Neuroradiology 02/2014; DOI:10.1007/s00234-014-1334-2 · 2.37 Impact Factor
Article: Role of Per-rectal Portal Scintigraphy in Long-term Follow-up of Congenital Portosystemic Shunt.[Show abstract] [Hide abstract]
ABSTRACT: Background:Congenital porto-systemic shunt (CPSS) has the potential to cause hepatic encephalopathy thus needs long-term follow-up, but an effective follow-up method has not been established. We aimed to evaluate the importance of per-rectal portal scintigraphy (PRPS) for long-term follow-up of CPSS.Methods:We retrospectively examined shunt-severity time course in patients (median 9.6y, 5.2-16.6) with intrahepatic (n=3) or extrahepatic (n=3) CPSS by using blood tests, ultrasonography or computed tomography (CT), and PRPS. Per-rectal portal shunt index (SI, cut-off 10%) was calculated by PRPS.Results:PRPS demonstrated the initial SI reduced in all intrahepatic cases from 39.7±9.8% (mean±SD) to 14.6±4.7% and also reduced in all extrahepatic cases from 46.2±10.9% to 27.5±12.6% during follow-up period. However, ultrasonography and CT disclosed the different shunt diameter time course between intrahepatic and extrahepatic CPSS. Initial shunt diameter (5.8±3.5mm) reduced to 2.0±0.3mm in intrahepatic cases, but the initial diameter (6.3±0.7mm) increased to 10.6±1.0mm in extrahepatic cases. All patients had elevated serum total bile acid or ammonia levels at initial screening, but these blood parameters were insufficient to assess shunt severity because the values fluctuate.Conclusions:PRPS can track changes in the shunt-severity of CPSS and is more reliable than ultrasonography and CT in patients with extrahepatic CPSS.Pediatric Research (2014); doi:10.1038/pr.2014.11.Pediatric Research 01/2014; DOI:10.1038/pr.2014.11 · 2.84 Impact Factor
Article: Estimation of proliferative potentiality of central neurocytoma: correlational analysis of minimum ADC and maximum SUV with MIB-1 labeling index.[Show abstract] [Hide abstract]
ABSTRACT: Central neurocytoma was initially believed to be benign tumor type, although atypical cases with more aggressive behavior have been reported. Preoperative estimation for proliferating activity of central neurocytoma is one of the most important considerations for determining tumor management. To investigate predictive values of image characteristics and quantitative measurements of minimum apparent diffusion coefficient (ADCmin) and maximum standardized uptake value (SUVmax) for proliferative activity of central neurocytoma measured by MIB-1 labeling index (LI). Twelve cases of central neurocytoma including one recurrence from January 2001 to December 2011 were included. Preoperative scans were conducted in 11, nine, and five patients for computed tomography (CT), diffusion-weighted imaging (DWI), and fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET), respectively, and ADCmin and SUVmax of the tumors were measured. Image characteristics were investigated using CT, T2-weighted (T2W) imaging and contrast-enhanced T1-weighted (T1W) imaging, and their differences were examined using the Fisher's exact test between cases with MIB-1 LI below and above 2%, which is recognized as typical and atypical central neurocytoma, respectively. Correlational analysis was conducted for ADCmin and SUVmax with MIB-1 LI. A P value <0.05 was considered significant. Morphological appearances had large variety, and there was no significant correlation with MIB-1 LI except a tendency that strong enhancement was observed in central neurocytomas with higher MIB-1 LI (P = 0.061). High linearity with MIB-1 LI was observed in ADCmin and SUVmax (r = -0.91 and 0.74, respectively), but only ADCmin was statistically significant (P = 0.0006). Central neurocytoma had a wide variety of image appearance, and assessment of proliferative potential was considered difficult only by morphological aspects. ADCmin was recognized as a potential marker for differentiation of atypical central neurocytomas from the typical ones.Acta Radiologica 01/2014; DOI:10.1177/0284185114521187 · 1.35 Impact Factor
Article: Risk Factors for Rebleeding and Prognostic Factors for Postoperative Survival in Patients with Balloon-Occluded Retrograde Transvenous Obliteration of Acute Gastric Variceal Rupture[Show abstract] [Hide abstract]
ABSTRACT: Balloon-occluded retrograde transvenous obliteration (B-RTO) has shown great potential in controlling acute gastric variceal hemorrhage, although rebleeding related to the procedure may occur in a small percentage of patients. The purpose of this study was to identify risk factors of perioperative rebleeding and prognostic factors of postoperative survival in B-RTO performed for acute episodes of gastric variceal hemorrhage. We retrospectively analyzed 39 consecutive patients who underwent B-RTO for gastric variceal rupture at our hospital between June 2003 and May 2011. Uni- and multi-variate analyses were performed to assess risk factors for perioperative rebleeding and prognostic factors for postoperative survival. Surgical success and complete eradication of varices were achieved in 36 cases (92.3 %) and 35 cases (89.7 %), respectively. Six patients experienced rebleeding either intraoperatively (n = 3) or within 1 h after B-RTO (n = 3). Child-Pugh class C was identified as a risk factor for rebleeding on univariate (P = 0.018) and multivariate analyses (odds ratio, 6.003; P = 0.014). With a median follow-up of 23 months (range 0-106.6 months), overall survival rates at 1, 3, and 5 years were 91.7, 74.7, and 67.2 %, respectively. Multivariate analyses revealed Child-Pugh class C as a prognostic factor for survival (relative risk, 4.014; P = 0.023). Although B-RTO is generally effective in the treatment of acute gastric variceal rupture, patients classified as Child-Pugh class C have a higher risk of perioperative rebleeding and shorter survival.CardioVascular and Interventional Radiology 01/2014; 37(5). DOI:10.1007/s00270-013-0807-8 · 2.09 Impact Factor
Article: Portal Vein Stenting to Treat Portal Vein Stenosis in a Patient With Malignant Tumor and Gastrointestinal Bleeding[Show abstract] [Hide abstract]
ABSTRACT: Abstract This report describes the successful use of portal venous stent placement for a patient with recurrent melena secondary to jejunal varices that developed after subtotal stomach preserved pancreatoduodenectomy (SSPPD). A 67-year-old man was admitted to our hospital with tarry stool and severe anemia at 2 years after SSPPD for carcinoma of the head of the pancreas. Abdominal computed tomography examination showed severe stenosis of the extrahepatic portal vein caused by local recurrence and showed an intensely enhanced jejunal wall at the choledochojejunostomy. Gastrointestinal bleeding scintigraphy also revealed active bleeding near the choledochojejunostomy. Based on these findings, jejunal varices resulting from portal vein stenosis were suspected as the cause of the melena. Portal vein stenting and balloon dilation was performed via the ileocecal vein after laparotomy. Coiling of the jejunal varices and sclerotherapy of the dilate postgastric vein with 5% ethanolamine oleate with iopamidol was performed. After portal stent placement, the patient was able to lead a normal life without gastrointestinal hemorrhage. However, he died 7 months later due to liver metastasis.International surgery 01/2014; 99(1):91-95. DOI:10.9738/INTSURG-D-13-00128.1 · 0.25 Impact Factor
[Show abstract] [Hide abstract]
ABSTRACT: To retrospectively evaluate risk factors for aggravation of esophageal varices (EV) within 1 year after balloon-occluded retrograde transvenous obliteration (B-RTO) of gastric varices (GV) and to clarify suitable timing for upper endoscopy to detect EV aggravation after B-RTO. Participants included 67 patients who underwent B-RTO for GV between January 2006 and December 2010. Whether EV aggravation occurred within 1 year was evaluated, and the time interval from B-RTO to aggravation was calculated. Factors potentially associated with EV aggravation were analyzed. B-RTO was successfully performed in all patients. EV aggravation at 1 year after B-RTO was found in 38 patients (56.7 %). Multivariate logistic regression analysis showed that total bilirubin (T-bil) (P = 0.032) and hepatic venous pressure gradient (HVPG) (P = 0.011) were significant independent risk factors for EV aggravation after B-RTO. Cutoff values of T-bil and HVPG yielding maximal combined sensitivity and specificity for EV aggravation were 1.6 mg/dL and 13 mmHg, respectively. The patients with T-bil ≥ 1.6 mg/dL or HVPG ≥ 13 mmHg had a median aggravation time of 5.1 months. All five patients with ruptured EV belonged to this group. In contrast, patients with T-bil < 1.6 mg/dL and HVPG < 13 mmHg had a median aggravation time of 21 months. T-bil and HVPG were significant independent risk factors for EV aggravation after B-RTO. The patients with T-bil ≥ 1.6 mg/dL or HVPG ≥ 13 mmHg require careful follow-up evaluation, including endoscopy.CardioVascular and Interventional Radiology 12/2013; 37(5). DOI:10.1007/s00270-013-0809-6 · 2.09 Impact FactorThis article is viewable in ResearchGate's enriched formatRG Format enables you to read in context with side-by-side figures, citations, and feedback from experts in your field.
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Kyoto University
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Johns Hopkins University
Baltimore, Maryland, United States
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Kyoto City HospitalKioto, Kyōto, Japan


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Short, Strong Signals
March 25, 2015|
Methylation increases both the activity and instability of the signaling protein Notch.
March 25, 2015|
Methylation increases both the activity and instability of the signaling protein Notch.
March 19, 2015|
Increasing the abundance of a chemical some microbes use to communicate with one another can help reinstate beneficial bacterial populations in the guts of antibiotic-treated mice.
March 18, 2015|
A census of adaptive immune system components in human skin reveals a variety of resident and traveling memory T cells.
March 5, 2015|
Researchers engineer water nanostructures to wipe out pathogens that can spoil food and pose health risks.
February 26, 2015|
A screen of 9,000 small molecules identifies a treatment that improves the targeting of mesenchymal stem cells to sites of damaged tissue.
February 25, 2015|
Researchers report an association between culture conditions and genetic changes in stem cells over time.
February 19, 2015|
Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure.
February 18, 2015|
A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks.
February 4, 2015|
Genetically modified T memory stem cells persist in patients for more than 10 years, and can differentiate into a variety of T cell types.
January 29, 2015|
Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.


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Fertilizing bare root trees at planting?
I have heard conflicting advice on whether or not to add fertilizer to the soil / in the hole when planting new bare root fruit trees. I am starting my first little orchard in a few weeks and I am hoping to get a definitive answer prior to that. Some places say to mix some fertilizer in the soil at planting and others say do not in order to avoid "burning" the roots. Anyone have definitive advice on this? If I should, what kind of fertilizer? Thanks!
Hi, Jay! For sure, no hot manure or chemical fertilizer in the hole, as these will burn the roots--often killing the tree. For apple, pear, peach, and cherry trees, I mix a cup or so of bonemeal into the dirt being used to fill the hole. Then I'll sprinkle a like amount of fishmeal on top of the ground around the new tree, and water it in. Enjoy your orchard. Misterbaby.
I plant in 25 gallon pots and don't add fertilizers at the time of planting.
I do add little...
Worm Castings.
Blood Meal.
Bone Meal or Garden Gypsum.
Kelp Meal.
Green Sand.
I mix it well with the soil as to much iron (blood meal) or too much calcium (Bone meal) is not good either.
In the ground I would do the same.
I have good growth with adding small amount old horse manure mix with soil at very low rate 1/2 to gallon manure mixed in soil to fill hole. For home owners it recomitted to use nuffing because that group will use to much and burn roots. Having a pile top soil months in advance fertlize so nitgreon die works for me to but them home owner could mess that up by not giving time needed to balance. Thisisme give good list of low fertilizers to add in planting mix.
Advice from Davis these days says to backfill with native soil only. Top dress with compost as a mulch. Any fertilizer you feel your soil needs should be added on top of the soil after leaf out, spread away from the trunk at and beyond the drip line. Al
Nothing should be thrown in holes IMO except maybe some calcium in acid soils. Generally nutritional amendments should be worked into soil of entire area previous to planting based on a soil test. Most important thing is getting pH in proper range. Your cooperative extension is a reliable source for a soil test kit which involves sending a soil sample to a lab.
Research I've seen shows that indeterminate growers such as peaches and J. plums will often grow more the first season with sup. N in a quick release form applied as suggested by Mr. B except I contend that you get same results w. organic as inorganic quick release. I consider fish emulsion pretty quick release. I prefer to use my own urine which is just a day or so slower than urea- it's a sin (in my private bible) to waste it and buy something that doesn't work any better. Dilute it well and water it in.
Determinate growers (plants that get there main flush of growth in spring) like apples and pears generally don't benefit the first year from such applications but may store some of it for greater vigor the following spring.
Plenty of soils are rich enough not to benefit from sup. N and when trees come into bearing I think slow release is the best source. Too often bearing age trees have too much vigor creating less flavored fruit.
I add a soluable low nitrogen high phosphorus fertilizer to a gallon or two of water that I saturate the backfill at planting and at two week intervals for the first month or so with good success on a number of different types of bareroot fruit trees. Originally came upon this practice from discussions with Jim Cummins who specifically recommends it for the planting of bareroot apple trees.
I guess I generally disagree here. Almost any organic fertilizers in small to moderate amounts seem alright in the planting hole: bone meal, cottonseed meal, fish meal, soy meal, kelp meal, compost, rock phosphate (probably not superphosphate), composted manure, etc. Osmacoat would probably be fine too. As a matter of fact, chemical fertilizers are alright EXCEPT that you generally cannot mix them well enough. Witness that soilless potting mixtures often have intermixed chemical fertilizers as ingredients.
I need a copy of your "private Bible" though I doubt my wife and kids are ready to practice your religion. A question was asked a while back on the Georgia forum about if it was safe to pour some beer they did not care for on their plants, and I believe I suggested they process the beer internally first as well as objecting that any beer could be bad. I have never collected my urine, but I have been known to water a tree, With the amount of trees it sounds you manage, I am sure you have to supplement this method, but I guess if the folks whose orchards you manage sounds like very sound green management to me.
Gone, I know what you mean. My wife has never warmed to the concept of storing urine and will hide my gas can pee jar if I leave it in the bathroom and guests are coming.
My clients don't get the benefit of my personal miracle gro. They either get N pulled out of the atmosphere at great energy expense or some bulky and heavy organic source that cost all that deisel fuel to get it to a distributer.
I love it when one of my clients come to a dinner party and rave on about my woderful and very large peppers or something pulled from my vegetable garden that they've just eaten and ask for my secret.
Thisisme, actually my pee is probably not particularly hi N by American standards because I don't eat all that much meat.
Jim Cummins expertise is in breeding rootstocks not nutritional management. I'd like to see the research that shows any meaningful response created by the addition of P. to most soils. I just haven't seen it, although the addition of P is often recommended.


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September 2007, TruckingInfo.com - Feature
By HDT staff
The ATA is pushing Congress and the Department of Transportation to set up a national system to identify truck drivers who have tested positive for drugs and alcohol.
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UKTV to Bring U.S. Version of 'Being Human' To U.K. Viewers
LONDON -- Digital pay-TV operator UKTV has inked a deal to bring the US version of cult British show Being Human to U.K. audiences.
The U.S. show is based on the BBC show of the same name and features three roommates living in Boston who try to live normal lives despite being a ghost, vampire and a werewolf.
PHOTOS: The Top European Media and Entertainment Industry Stories of 2012
The multiple channel operator owned by BBC Worldwide and Scripps Networks Interactive sealed the deal with program distributor Zodiak Rights to bring the show to the British side of the Atlantic on its flagship entertainment channel Watch.
The third season of the U.S. supernatural show currently airs on cable network Syfy.
Watch general manager Steve Hornsey described the show's dark take on an ordinary flat share as a "perfect fit" for the Briitsh channel.
The deal was brokered by UKTV acquisition executives Emma Sparks and Nicki McDermott, alongside Zodiak Rights' head of sales Anne-Marie Pardoe.
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From Christian Bale to Benedict Cumberbatch: Why British Actors Nab So Many American Roles
The Uncensored, Epic, Never-Told Story Behind 'Mad Men'


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Important question
What was it that caused 5 companies of trained soldiers to turn tail and run from a bunch of farmers and shopkeepers at the Old North Bridge?
Answer: Well aimed and concentrated musket fire---the skill of marksmanship. This is where the heritage of the American rifleman began.
This nation was started by riflemen.
It is the responsibility of every American to pass along the tradition that started on that day---before it dies. Want to get started?
One way is to attend an Appleseed marksmanship clinic.
America is an idea. That idea only arose once in all of history. If it is lost here, it may never arise again. Think about it. We're not talking about the United States. There is a lot more at stake here than preserving the United States.
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So I've been searching around for quite sometime now trying to find different techniques for carbonating seltzer water in a 5gal corny. I've read a bunch of different post from folks about how they carbonate seltzer, how much psi to use, temp and how much line, but I'm still trying to find the most efficient and fastest methods for carbing seltzer.
My technique,
5gal corny keg
fridge temp around 35 to 38 degrees
psi at 35
Set and forget
Usually takes around 7 days to reach the level of carbonation I like (store bought level). This methods has always worked for me. Though the last few times the water hasn't been quite as carbonated as I would have liked. I usually carb 2 kegs at a time and it usually takes about 2 to 3lbs of Co2. Ultimately I would like to save as much Co2 as possible and carb as fast as possible.
Sometimes i forget to purge my kegs after filling up with water which I assume might have some effects? I usually also connect the Co2 up right after filling up the keg with tap water. I assume the temp is around 40 to 50 at this point.
I've also tried the shake method, which doesn't work out to great seeing as I have to balance my 5lb Co2 tank while rolling my keg around on the ground. The time I did try this method my water temp was around 40 degrees and I rolled the keg around for prob 20 min. The carb level was no where near the way I wanted it.
One technique that I've also tried is shaking the keg at the beginning. Basically filling the keg up with cold tap water attaching the Co2 and shaking until I don't hear the gas dissolving any more (couple mins), then leaving it to sit checking it every couple days. This method didn't work any better for me than the set and forget method. Still took around a week for the water to carb.
I tried serving my seltzer a few different ways. Once its ready unhooking the Co2 and connecting 5ft of 3/16" beer line. The pressure from the keg pushes out the seltzer just fine. Sometimes have to reconnect Co2 to add more pressure when the keg gets low. Never had an issue with line being to short, though the seltzer does come out with some force. Could this been causing me to loose Co2 in my seltzer?
Thats the way I normally serve. I've been thinking about trying a few different techniques. Leaving the Co2 connected and serving at 10psi. Leave the Co2 connected and serving at carbing pressure (30 to 35psi) would I need 25 to 30' of 3/16" for this? I'm also going to be purchasing a tap soon to serve my seltzer from. Any recommendations? I love the old soda fountain style taps, but they are a bit pricey.
What do you see wrong with my techniques? What works for you? Any advice is much appreciated! Happy Brewing!!
Action Jackson
Actionj; what my family does is fill a keg with water (and it comes out about 35-40 deg here) hook up the co2 and for the next few hours, shake the keg when we think about it, and usually by the next morning it's carbed enough to drink. I don't have a fridge to keep mine in, but it stays cold where I keep it. As for purging, I think that's something to do with beer, if oxygen gets to the beer, it will cause problems. With water, there's no problems. I guess it's all in what works for you.
The book Fix the Pumps has pages and pages on this subject. He says purging air is very (in italics) beneficial because air displaces co2 in solution, but more importantly it triggers the premature release of co2 when pressure drops because air releases first and agitates stuff. So not only does he say purge air out from the beginning, but after pressurizing with co2 you can release the pressure to kick air out, then pressurize co2 again, then repeat up to 3 times. Of course that doesn't conserve co2. He notes many other factors besides air and the important temperature, such as no soap residue or things that can nucleate bubbles.


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I prefer being able to understand the lyrics in the music I listen to :] makes sing a long a lot easier.
Just imagine this, but you trying to sing korean.
They say that I can't last a day in the real world
I say you wouldn't survive one night in mine
Formerly known as Eniah/Enyah
Good night Puri.
Good night Asmekiel?
Night Pur Asmek.
"#Got99ProblemsAndTreannAintOne" ~ElyPop


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Today I have tried to describe the different moments/phases come about in a Blogger's life. I am sure you must have experience at least anyone from these entertaining GIFs. 1. When a Newbie creates a blog 2. When a Blogger first time see its blog that went live 3. When you are ... Read More »
Best Web 2.0 Sites to Create High Quality Backlinks
I previously published a post in which I have shared about 25 web 2.0 sites. These sites are actually used to create quality backlinks to create more traffic. There are a number of link building strategies that help your blog/website in getting good rank at search engines. Article submission, directory submission or press release etc etc. do not provide ... Read More »
200 Free Article Directory List to Get High PR Quality Backlinks
A free article directory offers you to submit articles for free and link them back to your blog or any other website by using relevant anchor text. High PR and reputed article directories provide quality backlinks to your blog/site and a large amount of traffic. Here is a list of more than 200 free article directories that ... Read More »
How to Get Approved Google Adsense Account in One Hour?
Google Adsense account is what all bloggers struggle for… after establishing a successful blog. But as we all know that there are some conditions proposed by Google for blogs/websites before applying for adense account to avoid any refusal. Today's tutorial is for all those who want to make money with adsense and found it difficult to get an approved ... Read More »
WordPress Resources for Beginners to Learn How to Use WordPress
WordPress is one top most platform in the entire online world. WordPress beginners would get benefit from this WordPress guide to learn how to use WordPress. No more wait now its time to share few best WordPress resources for beginners like WordPress websites/WordPress blogs, 10 Websites about "WordPress" 1. http://wordpress.org – On this site, you can download and install a software script called WordPress. To do ... Read More »
How to Use Facebook and Tips for Using Facebook in 2014
Facebook is no doubt a top most social networking website that is extensively used by people in all over the world. Although there is no need to know that how to use facebook as everyone is much familiar with its features, apps etc… But there are a number of tips on using facebook which would help you to enjoy ... Read More »
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Animated CSS3 Download Button: If you have Blogger Blogs about Softwares, Apps and Templates you provide the download links for the respective stuff. Then the best practice is to convert your link into an animated CSS3 download button. Because visitors loves creativity and ease. We have to provide our visitors a much more navigative interface for getting leads in ... Read More »
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High PR Dofollow blogs play a significant role in getting good rank on Google SERPs. Although quality content is a key factor in getting ranked but pageranks has its own place to improve your SERPs and high pagerank is generally based on quality content and qualitybacklinks from high PR websites. Dofollow backilnks ad more to your SEO as ... Read More »
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Quality Backlinks Aaaah! Are always much loved… Being a webmaster you must know about the actual significance of high quality backlinks. They are always in demand by webmasters and Internet Marketers. –> They are a most prominent part of Off-Page SEO. They are we can say somewhat responsible for getting good rank in SERPs. Although there are also a number of other ... Read More »


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Wed, 1 Apr 2015
Citigroup Hires New Global Head of Prime Finance
Morningstar's Christine Benz demonstrates how to make a bucket portfolio best work for you, touching on allocation, RMDs, other income sources, and more.
Financial planner Mark Balasa and Morningstar's Christine Benz and David Blanchett tackled viewers' most pressing retirement questions, from determining savings rates and income needs to planning for Social Security and maximizing retirement accounts .
Director of personal finance Christine Benz will help you check your true exposures and stress-test your holdings in session 2 of Morningstar's 2012 Midyear Financial Checkup.
In this special midyear presentation, Morningstar's Christine Benz demonstrates how to gauge the viability of your current plan, evaluate positioning, troubleshoot risk factors, and much more.
Morningstar's director of personal finance outlines how to gauge your portfolio's viability, evaluate your allocation, troubleshoot risk factors, and more in this special Web seminar presentation.
In this special presentation, get the answers to key questions about the quality of your plan, whether your savings are on track with your goals, how to allocate assets, and what to do with assets when you leave your job.
Premium Member Video: Financial experts John Ameriks, Sue Stevens, and Bill Bernstein address how to allocate fixed-income assets, the importance of total return, the role of annuities, retirement distribution rates, and more in this special panel discussion hosted by Christine Benz .
Investors should keep an eye on valuations and gauge their portfolios' vulnerability to inflation and rising interest rates when rebalancing, says Morningstar's Christine Benz .
Don't swap your whole fixed-income position for dividend-paying stocks .
©2014 Morningstar Advisor. All right reserved.


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Simba Backpack
Style Number: 49273007
Product is not available
Special Offer
Additional 60% Off
Final Sale
Carry your stuff with Disney's Simba from "The Lion King" in tow! This adorable backpack has an all-over Simba print and faux leather trim throughout with adjustable back straps. The exterior has two front pockets that close with a magnetic button detail and a top flap that folds over with a faux leather strap that dangles off and snaps into place with a magnetic button. The backpack can also be cinched tight with the faux leather drawcords while the interior features plenty of storage space.
- 13" Height x 11" Width x 5" Depth
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Eastern Newswire
Results 1 - 17 of 17 for "u:middlesborodailynews.com" in Eastern, KY
Representative Tim Couch, R-Hyden, who represents part of the Eastern Kentucky coalfields has filed a House resolution that if passed would ask the United States Congress to pass a law requiring the U.S. Environmental Protection Agency appear before them to seek approval of any rule or regulation they propose. Rep. Couch's bill is being called the "Coal Jobs Saving Resolution." Comment?
The Eastern Kentucky Expo Center has been turned into a hub to distribute water to area communities that are still experiencing shortages. Pike County Emergency Management Director Doug Tackett told WYMT-TV that the facility, which is normally used for concerts, has loading docks, equipment and a good amount of storage space. Comment?
Forward in the Fifth seeking nominations w/Photo
Forward in the Fifth, a nonprofit education organization that helps to raise educational attainment levels in the Fifth Congressional District, is seeking nominations for the Appalachian Leaders in Education Awards. Now in its fourth year, the AppLE Awards recognize leaders in education, including local parent and student groups, who have made significant contributions to promote and support education in Forward in the Fifth's 45-county primary service region. Comment?
EKU providing media content for SOAR initiative w/Photo
Students and faculty in Eastern Kentucky University's Department of Communication are continuing to provide media content for the Shaping Our Appalachian Region initiative. Dr. Ginny Whitehouse, associate professor in the department, assigned her second-level reporting and writing for the Media students in-depth stories about issues that surfaced during the regional listening sessions. Comment?
3 Bobcats sign for football w/Photo
Daily NewsHayden Gilbert held a signing ceremony on Friday at Bell County High School. Gilbert will be playing football at Union College. Comment?
Investments being made in Kentucky's Promise Zone w/Photo
A statement says the Kentucky Promise Zone has attracted more than $109 million in funding, with investments being made in education, medical facilities, higher education, workforce training and anti-drug initiatives. The Appalachian Regional Commission awarded a $250,000 grant last year to launch the Promise Zone program in eight counties in southeastern Kentucky: Bell, Harlan, Letcher, Perry, Leslie, Clay, Knox and Whitley. Comment?
2015 Rogers Scholars deadline is Saturday w/Photo
The deadline for local high school sophomore students to submit applications for The Center for Rural Development's 2015 Rogers Scholars program is Jan. 31. Rogers Scholars is an intensive one-week summer youth leadership program for high school students within The Center's 45-county primary service area in Southern and Eastern Kentucky. The program emphasizes the development of technological skills and builds in participants a sense of leadership, an entrepreneurial spirit, and a commitment to rural Kentucky. Comment?
An Australian-based investment firm will build and manage a 3,000-mile network of fiber optic cables across Kentucky that state officials say will improve broadband access and cellphone service in some of the country's most impoverished areas. Democratic Gov. Steve Beshear and Republican U.S. Rep. Hal Rogers said Tuesday they believe it to be the first contract of its kind in the country. Comment?
Coal's costs keep adding up w/Photo
We hear a lot about a war on coal. But, to borrow another trendy phrase, amnesty is the real threat - amnesty for the coal industry. Comment?
Platoons working for UK w/Photo
Daily NewsKentucky freshman guard Tyler Ulis handles the ball during the Wildcats' win over Providence on Sunday. Top-ranked UK hosts No. Comment?
Students find learning at 'The Holler' w/Photo
What happens when you take a free online delivery system and create coursework designed for a specific culture and region? What if you apply that philosophy using technology to change education and access to learning in Central Appalachia? And just to make it feel like home, why not call it the "Holler." Designed as a social learning network for students in Eastern Kentucky and Central Appalachia, founder and creator Bruce Parsons said the Holler provides an accessible conversation for technology and learning and serves as a delivery tool for open coursework and other educational initiatives. Comment?
Mobley thriving at EKU w/Photo
Though his sudden decision last December to transfer stunned Wildcats coaches, the move just down the road from Lexington has turned out well for Mobley and the Colonels entering Saturday night's game against Eastern Illinois . As EKU's featured back Mobley has rushed for five touchdowns and an OVC-best 530 yards and ranks third nationally in the FCS at 8.2 yards per carry. Comment?
How much longer for Harlan County? w/Photo
Sometimes I wonder if the people in Hal Rogers' office get a kick out of sending me emails touting road projects in eastern Kentucky. Of course, all the road project emails I've received over the decade or so from them have one thing in common - none of them mention Harlan County. Comment?
Schools struggle as families flee coal country w/Photo
When it opened in 1990 amid boom times deep in eastern Kentucky coal country, Shelby Valley High School had nearly 1,000 students, with enough demand that it built an addition the next year. Now the mines are closing, and the school big enough for 1,200 students sits at half capacity. Comment?
Citizens back tobacco ban w/Photo
Citing Kentucky's continued worst state ranking in smoking and cancer deaths, Governor Steve Beshear announced Thursday that all executive branch state property campuses will be tobacco-free effective November 20 - the day of the Great American Smokeout. The decision is supported by a large majority of Kentuckians says Susan Zepeda, President/CEO of the Foundation for a Healthy Kentucky. Comment?
Citizens back tobacco ban w/Photo
Citing Kentucky's continued worst state ranking in smoking and cancer deaths, Governor Steve Beshear announced Thursday that all executive branch state property campuses will be tobacco-free effective November 20 - the day of the Great American Smokeout. The decision is supported by a large majority of Kentuckians says Susan Zepeda, President/CEO of the Foundation for a Healthy Kentucky. Comment?
Does surface mining harm the health of people in the east Kentucky coal field? And why haven't more elected officials participated in this summer's meetings to gather ideas to diversify and improve the economy of Appalachian Kentucky? Those were the two biggest questions raised Friday as 18 leaders of the Shaping Our Appalachian Region initiative ... (more) Comment?
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CalamityCakes ...
So pretty. What cutter did you use for the small flowers with the pointed tips?
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CakesDecor Quarterly Awards - Spring 2015 - are ready. Entry opens in .


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Chapter II The Forest
I was going to run to the final stop, and beat the bus there by going through the woods. That was my plan. It wasn't a very good one, but it was the only one I could make up at such short notice. Running through the tress, I jumped over roots and ducked under branches. My heart began to pound, and my legs felt like lead weights. I wasn't going to be able to keep up this pace for much longer. "Hopefully," I thought, "I won't need to".
As I ran, I realized I had no idea where I was. I looked ahead of me and saw no trees, and took a risk. I turned my head to look up at the sky above, to use the sun to find the right direction. This idea was destroyed, however, when I couldn't find it. With my attention averted, I never saw the branch ahead of me. When I had turned my head, it was too late. "I guess the gamble didn't pay off," I thought to myself as I ran straight into the tree.
The first thing I saw when I awakened was a brown blurred figure. When my eyes focused, I was able to tell that it was a deer. The animal had its head right over my face, seemingly interested in my predicament. The beast stopped mere inches from my face. I could feel its hot breath and began to back away. The animal suddenly bellowed and galloped off. I felt a wave of relief as I watched it disappear into the forest. Then a different thought entered my mind. "What could scare the deer off like that," I pondered. The look on its face had been one of pure terror. Goosebumps grew on my arms, and I turned around and saw……. Nothing.
There was absolutely nothing there, not even a weasel or a fox. It was then that I first considered what time it was. I had no way of telling how many minutes had passed, but I was sue I had missed the bus. I considered for a moment, and decided to go home. There was no point in staying, as school had probably already started. If I was really lucky, I might just be able to arrive back before my parents back. That was a big IF, but it was my only course of action. The realization suddenly hit me I had no idea where I was. Without the sun or some kind of compass (I had neither) to guide me, I wasn't going anywhere. I sat down on a nearby log, and tried to decide what I was going to do next. Then thunder boomed in the distance. As if that was a cue, the rain began to fall. It was fall, so there weren't any leaves on the trees. I got up and began to search for some shelter.
The trickle turned into a downpour, and I still had no cover. It was thundering and raining so hard, it seemed the very sky was angry with me. Just as I had given up all hope of finding any relief from the ceaseless rain, a flash of thunder illuminated a building in front of me. I didn't think about the fact that I been through these woods hundreds of times and not seen this structure before, all I was concerned with was finding protection from the elements. I quickly entered the building. I was suddenly aware of a musky smell to the air, as if it was……old? Again I didn't notice this and stepped further inside. The room was very dark, the only light coming from the opening behind me. As I moved inwards, away from the falling rain. I bumped into something. Then the entire building began to shake and a wall fell behind me. All light disappeared leaving me in complete darkness.


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So Christmas in 25 degree sunshine....
Due to the high number of trips to the UK over the last 12 months we decided to spend Christmas in Muscat. This all sounds relatively straight forward until you start planning a traditional Christmas dinner with all the trimmings. Luckily one of our dinner guests had their brother coming to visit from home and so a large ham was ordered to ensure we maintained a level of normality. Turkey, veg and cranberries all sorted and the only thing left to do was get in the kitchen and get it sorted.
Christmas morning was a strange experience as when we got up and looked out, not only was it still warm, but everyone was at work and going about their day as normal. Takes a while to remember we live in a Muslim country. Late morning and our guests had arrived. Off to the marina for a couple hours wake boarding, knee boarding, surfing and trying to get towed on an inflatable pink chair. Santa did a fine job as the pictures show.
Don't spill the hot toddy
Enjoying the first course in the garden
Our Christmas entertainment. One of the girls managed to recite the whole 'Twas the night before Christmas' poem from memory whilst her sister did an amazing rendition of Rudolph the Red Nosed Reindeer
And then main course, led to dessert, which led to a late night. Really good fun and was great spending it was some good friends. Not quite the same as home though...


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I loved the friendliness of the staff and the cleanliness of the room. Also loved the view from our room and the fact that there was a refrigerator in the room.
I wish there had been a microwave in the room.
River view was great, very clean, friendly staff and organized.
The breakfast left a bit to be desired but it's Cheboygan mi, so it was more that acceptable.
I like the low cost and the easy access to the highway. The staff was very friendly and helpful. Breakfast was hot and had seating in the lobby.
The colors and décor was from the fifties. Everything is clean and neat, just not current colors.
Balcony did have a good view of the lake and the free breakfast was decent
Overall condition was poor. Bathroom was not clean andhad hair in the sink
and tub. Wallpaper was peeling off In several places and there
was a chunk of plaster Missing from the ceiling. I would not stay
here again.
Not much. Pool is ok.
Room old and out dated, beds sucked real bad!
I had no stay at the Best Western! It was closed when I arrived at the INN about 6:30 PM. They were closed. A note on the door said to go to a different Inn. I did and paid a higher rate. KAYAK or BEST WESTERN I do not know but GOOE on you and Best Western!!
Easy In and Easy out. The price was about right for the facilities. Check in was fast. Breakfast was great. Beds were pillow tops and comfortable.
I have mobility problems and the elevator was a one end of the complex and our rooms were at the far end away from the elevator.
There were ramps but I still had to walk too great a distance. I would not stay here again even if on the ground floor because I would have to go upstairs for breakfast with no direct elevator.
Old decor, but very friendly staff and extremely clean.
Location....close to town. Could walk to everything.
Nothing bad to report.
To start the remote didn't work. They have a pool but no hot tub. Then to end our fifteen minute stay, the bed linen had softball size stains all over the bed. Obvious from the naked eye and being dark in the room. Front desk made me call hotels.Com to get my money back which happened then we went to a different hotel. So disgusting.
The person at the desk was over the top helpful with attractions and getting around town. Manager was hands on, and everyone paid attention to every detail. Place was excellent in every way as noted above.
Location to the ferry dock was excellent, amenities were top notch, and staff was very helpful
Everything was fine
The location was very nice
No there was nothing that I didn't like
easy to get to
rather pricey
The manager was very accommodating.
The front desk staff were poorly trained. Of the two I encountered, one failed to ask for identification when I requested a new room key and the other was unaccommodating and rude. The breakfast was very unimpressive and the hot tub was not working.
Great staff!
Facility was old and needs a complete make over!!
The view of the bridge was amazing.
The receptionist's are very rude. It took over 2 hours past the guaranteed time to check in to get into our room. The pool was disgusting, we only stayed in the pool for 5 minutes before we left. Overall, i would find another place to stay.
We had a great time in the water park
having to leave
Location was great. Staff very hospitable.
Unreliable Internet
The front office staff was very helpful and facilitated ferry tickets to Mackinac Island at a discounted rate. Inn was quiet, clean and comfortable
They did offer a breakfast of donuts, muffins, and juice, but a better continental breakfast would be a nice addition to their services.
Wir sind weder Anbieter noch Verkäufer.
Wir bestimmen die Preise der angezeigten Reiseprodukte nicht selbst. Daher können wir nicht für die Produkte anderer Unternehmen garantieren.
Wir durchsuchen und sammeln riesige Mengen an Daten für Sie.
Unser Service erlaubt es Ihnen, die Angebote Hunderter Reise-Websites schnell und einfach miteinander zu vergleichen. Als Suchmaschine können wir nicht für die gefundenen Preise garantieren.
Warum sind die Preise nicht in jedem Fall akkurat?
Bei Flugtickets, Hotelzimmern und Mietwagen ändern sich ständig die Kontingente und Angebote. Preisdaten werden zwischengespeichert und aktualisiert, und all das bei Hunderten verschiedener Airlines und noch mehr Buchungssystemen, die allesamt dieselben Reiseprodukte zu verkaufen versuchen. Es kann also sein, dass ein Angebot nicht mehr zum selben Preis erhältlich ist oder bereits ausverkauft ist, bevor Sie zur Webseite des Anbieters gelangen.
Falls Sie weitere Fragen haben oder uns einen Preisfehler melden möchten,
und wir werden Ihnen so schnell wie möglich weiterhelfen.


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The Dwarves with a record on Fat? Yeeah! And it's about time.We're longtime fans and while we've admittedly squirmed at some of their record covers over the years, that's part of what makes The Dwarves the "motherfucking rock legends" that they are. Plus, you know, they invented rock 'n' roll! You know what to expect: high velocity punk rock 'n' roll with loads of hooks, visceral cover art and raucous live shows. So of course we wanted to work with them! A handshake deal was struck at a Bl'ast! show and the result of this summit of world powers is the four-song blast, Gentleman Blag. Due out late this Fall, the EP features a rare cover appearance from lead vocalist Blag Jesus, alongside the cover models you'd expect. But you're going to have to wait until you get this limited edition slab of wax in your hands to discover the equal opportunity ideals on display when you turn this sucker over… if you dare! Like the recent album on Recess Records, Gentleman Blag was recorded by Andy Carpenter at Brand Bjork's (Kyuss) studio and features guest vocals by Dexter Holland (Offspring) and Rex Everything a.k.a. Nick Oliveri! And, coming full circle, the recording features ALL the Dwarves, including HeWhoCannotBeNamed and Salt Peter from the original lineup. And now, a brief quote from the man himself, Blag Jesus:
'The song "Kings of the World" reminded me of that Fat Wreck Chords sound-straightforward punk, big harmonies and lyrics about social issues. In other words, it was just the opposite of "Gentleman Blag," which is about how big my cock is. Combined with a stoner style track from Nick Oliveri and another song so short it's over before it starts, I thought we had a perfect Fat 7"!'
We hope you've got your reading glasses and dancing shoes handy, 'cuz Mad Caddies have a brand new lyric video premiering today at AUX! The vid is for the contagious ditty "Down and Out", the lead track from their latest album, Dirty Rice.
Check out their upcoming tour dates below!
10/14/14 Bend, OR Domino Room
10/15/14 Tacoma, WA Jazzbones
10/16/14 Kelowna, BC Canada Habitat
10/17/14 Edmonton, AB Canada Union Hall
10/18/14 Calgary, AB Canada The Gateway
10/19/14 Banff, AB Canada Wild Bill's
10/21/14 Spokane, WA Knitting Factory
10/22/14 Boise , ID The Shredder
10/23/14 Sacramento, CA Midtown Barfly
10/24/14 Petaluma, CA Phoenix Theater
10/25/14 Santa Barbara, CA Velvet Jones
10/26/14 Long Beach, CA Gaslamp
Today is the day. You can now listen to a new LAGWAGON song! "The Cog in the Machine" is being premiered by Vice/Noisey.
Pre-orders are live! PLEASE PLEASE PLEASE read the details below before ordering. There is PLENTY of colored vinyl available, so PLEASE take your time and get your order right the first time!
ALL Hang pre-orders come with two BONUS TRACKS! The Deluxe Vinyl version contains a bonus 7" with the two surprise songs. For Standard Vinyl and CD, your digital download will contain the bonus songs.
ALL physical pre-orders (Deluxe Vinyl, Standard Vinyl, CD or Bundle) come with a free DVD!
ALL bundle's contain a free Lagwagon Hang poster!
Deluxe vinyl – Gatefold Jacket with LP and bonus 7" packaged inside.
Three different color configurations. One color is ONLY available with the bundle. The other two colors available separately. If you order TWO deluxe color vinyl LP's, you will get the TWO different colors. If you order TWO deluxe color vinyl LP's AND one bundle, YOU WILL GET ALL THREE COLOR VARIANTS (while supplies last).
Bundle: Deluxe Gatefold LP with bonus 7" (both color), DVD, deluxe full-color slipmat, Hang poster, and black American Apparel t-shirt (remember, AA shirts run a bit small).
T-shirts: We have women's sizes available separately. These are also American Apparel and run small.
While Fat has a long history of bands influenced BY the Ramones (Chixdiggit!, Teenage Bottlerocket, Masked Intruder, Screeching Weasel), releasing an album FROM an actual Ramone is a first and a true honor. Last Chance to Dance is CJ Ramone's second solo album and was recorded with the stellar backing band of Steve Soto (Adolescents), Dan Root (Adolescents), and David Hidalgo, Jr. (Social Distortion). With a sound and style true to the Ramones, CJ has created a positively infectious punk rock record. Sometimes you just "need a Ramones fix," the expression goes, and CJ Ramone's Last Chance to Dance satisfies that craving in spades. Don't believe us? Go here and listen to the first track and single, "Understand Me." The 7" will be released on October 14th (pre-order here) with the album arriving on November 25th. And now, a word from the man himself, CJ RAMONE:
Hey kids Cj Ramone here. My new record Last Chance to Dance is coming out November 25th!!! It's 12 tracks of everything you'd expect from a Cj Ramone record. Hard chargin' and vicious with some sweet melodies to smooth out the edges. Keep an eye for dates for our 2015 World Tour. See y'all on the big road.
Swingin' Utters are gearing up to release their eighth full-length album in November— Fistful of Hollow —and this is your first chance to hear some of the magic these prolific songsmiths have conjured up this time around. The spotlight in this, the album's title track, is shining directly on guitarist/vocalist/songwriter Darius Koski. Get yourself a "Fistful of Hollow" right here, right now!
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27Mar, 2015
Head over to New Noise Magazine for Western Addiction's second European tour journal!
27Mar, 2015
Check out all the new Get Dead tour dates!
26Mar, 2015
STRUNG OUT's tour kicks off next week! Read a new review of their latest, Transmission.Alpa.Delta to get you pumped!
25Mar, 2015
Watch Bad Cop/Bad Cop perform unplugged over at Punks In Vegas!
24Mar, 2015
Less Than Jake are heading out on the second leg of their tour with Reel Big Fish this May and June!
24Mar, 2015
Lagwagon was just added to the NOFX shows in United Kingdom with Alkaline Trio playing too. Making it one of the best tours of the year!
23Mar, 2015
New review of Western Addiction's I'm Not the Man That I Thought I'd Be on Dying Scene.
20Mar, 2015
Weekend Reading for y'all! SLUG Mag knows what's up! Check out their glowing reviews for toyGuitar, Swingin' Utters and NOFX!
20Mar, 2015
Check out Jason Hall from Western Addiction's European tour journal with The Flatliners and Lagwagon.
20Mar, 2015
Read another stellar review for Strung Out over at New Noise Mag.
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Plan pitched to provide access at Fort Pierre reservoir
FORT PIERRE (AP) -- Officials are pitching a plan to provide better fishing and boating access to the Richland Reservoir and dam on the Fort Pierre National Grassland.
The media reports that the South Dakota Department of Game, Fish and Parks and the U.S. Forest Service are considering a cluster of structures on the reservoir.
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NBC 5 Meteorologist Remeisha Shade updates the forecast for Saturday, March 28, 2015 Watch Video
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Downtown Evergreen has a blend of established businesses and new ones putting down roots, and their customers sometimes struggle to find a parking place and walk precariously along Main Street where the sidewalks end.
During a March 24 meeting on potential updates to a community plan for Evergreen, Jeffco planner Russell Clark asked attendees to identify "the good and the bad" in the downtown area.
Later, a reporter asked downtown business owners for their own answers to that question.
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Canyon Courier is your source for local news, sports, events, and information in Evergreen, Colo, and the surrounding area.


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Bill would have cops keep tabs on gun-purchase database
The state senator who represents the Isla Vista community that was ravaged by a mass murder last month has introduced legislation to require law enforcement to check California's gun-purchase database before investigating someone who may be in danger of committing violence.
Senate Bill 505, by Sen. Hannah-Beth Jackson, D-Santa Barbara, would require officers to search the state Department of Justice's Automated Firearms System database in such cases.
Police checked on Elliot Rodger, the 22-year-old authorities say killed six people in Isla Vista before killing himself, after his parents alerted them of his violent video rants just a couple weeks before the shooting. The officers did not find evidence that Rodger posed a threat to himself or others.
Jackson's Senate Bill 580 would provide funding to help enforce California's existing gun laws: $5 million in grants for local law enforcement agencies to take guns from people who are not allowed to own them; $10 million over three years to upgrade the Department of Justice's data systems used to register gun ownership and conduct background checks; and $50,000 for training police in using the gun-purchasing database.
"Both of these bills are about making better use of the tools and the laws at hand to help prevent gun violence," Jackson's said in a statement.
Craig De Luz, lobbyist for the California Association of Federal Firearms Licensees, said SB 505 mandates something law enforcement can already do. SB 580, he said, would unwisely divert fees paid by gun owners that is meant to be used to promote gun safety.
– Laurel Rosenhall
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