text:
things I stole: 'Do a Dozen' (folding laundry)
Looking at that 2000 link on the "Posts from before Oct '04" link, I see that I flat-out ripped off an idea from a former member here, --sage.
She wrote, on a thread about folding laundry & putting away:
"Here's another laundry tip--
Sometimes I procrastinate & let the clean laundry pile up in the basket. So now I tell myself I will fold 12 items & put them away. Just do 12. But then next thing you know I will do 5 more, then 10 more, & so on. Before you know it, the laundry is folded & put away."
So, that's what I started to do, and I call it "Do a Dozen," and I recommend it all the time, and I have forgotten to credit it! In fact, I think I even eventually lost that vague sense that I'd been given that idea from someone else.
So, to anybody else whose great idea I have ripped off, thank you, and I'm sorry! LOL!
Well, Your Honour, I plead *guilty* to the crime of being a receiver of stolen ideas. Do I get reduced sentence if I plead ignorance of the fact that the ideas were "fenced goods"?
Talley Sue, you are hereby condemned to hard labour.. you are to "Do TWO Dozen" today. LOL
That's OK, Talley. You live and learn. Seems to me everything had to come from somewhere, even ideas.
My husband is a writer. When our kids were in school worrying about plagiarism (and I was working in a HS library charged with rooting out plagiarism amongst the students) Dad always said, "You read and you write. You have to get your information from somewhere. Just be sure you credit your source." That's what you just did, albeit a little late.
I was always giving the benefit of the doubt to the students...Here's my thinking: You incorporated -sage's idea into your own thinking, making it your own. Did you actually use -sage's exact sentences when you made your suggestions? Probably not. I think you're an editor, so you'd be well aware of plagiarism issues.
As self-appointed appeals judge on this thread, I hereby reduce your sentence to loads already folded. It's a good idea!
Thanks, guys! (and hey, I'm the one who named it, right?)
And I always say when people retell jokes, "you get credit for having recognized it as funny, and for the delivery you gave it."
I call it "my famous pumpkin bread," but it was somebody else's recipe first. I *have* tweaked it (double the cinnamon, half again the nutmeg; put a cinnamon-sugar crust on top using maple syrup & butter), which is an important part of the appeal. And I mix it differently (not sure how much that changes it).
Actually, this would be a good opportunity for us all to pass on the great ideas we *have* "stolen" from someone else.
Think of them as "tried and true." And ourselves as an integral part of their validation. They work for us; that only ADDS TO their inherent value.
What great organizing idea have you snagged to be your own? Have you tweaked it?
I snagged from somewhere the "leave no evidence" idea--that when you're done making a sandwich, or wrapping presents, or whatever, you erase all traces of what you were doing, so someone coming into the room 5 minutes later won't say, "Aha, Watson, someone has been wrapping presents. See the telltale signs of the tape dispenser, scissors, and tissue paper?"
I think it is perfectly acceptable to take a great idea and hone it until it is "truly your own." But it never is truly your own. You stand on the shoulders of giants. And someday, another person will take your idea and improve it.
I think that framing the concept with a clever saying makes it easier to impart to others.
I am a writer, and I know perfectly well that when I read or study or interview or watch a play or movie or just listen to somebody interesting at a cocktail party, or to my friends around the dinner table, I am likely to absorb and then recycle ideas. What made me quit worrying about that was the realization that it was arrogant to think that everything out of my mouth, or pen, had to be (or could be) entirely original. You make things your own when you understand them, interpret them, and relate them in your own words, with the filter of your own experience, illuminated by the light of your own truth.
Everyone who participates in this forum gives ideas as gifts. We honor those gifts when we receive them. That's not the same as stealing, don't you think?
So I guess you are holding the recipe hostage until I come up with something. ;) Here goes:
This seems so elementary to me that I doubt that I stole it, but it escapes everyone in my husband's family: put like things together and mark what's in the box.
For example, in my office closet, there is a shoe box with a yellow sticky on the end with the word TAPE. That's because when we moved out of our last house, I went around and collected all the tape dispensers - scotch tape, box tape, duct tape, masking tape. We must have had 20 rolls of tape that had somehow accumulated. I have a similar one called BATTERIES, and another called PENS and PENCILS. This is the kind of stuff that normally fills up junk drawers, yet isn't there when you need it.
I am currently helping my 81 year old MIL with a massive basement clean-out project. There is just no rhyme or reason for where or why she places things in her house. Her clothing is in the basement while her upstairs bureaus are filled with Christmas ornaments. Shouldn't it be the other way around?
So, now, about that pumpkin recipe???
Perhaps the way I motivate myself has led to a unique way of viewing the organization process. Here goes:
I try to see more than one benefit from an activity on my to-do list.
For example, I'm trying to exercise more, so I get out there and actually do that yard work. And I don't complain about how hard it is, or how much I sweat, because it counts as aerobic exercise if I do it briskly enough. So I get the yard picked up AND I get the exercise that will help me loose weight and help me to sleep better that night. Wait! That's THREE benefits! Four, if you count keeping my heart healthy and living longer. So do you see what I mean?
Here's another example: If I do my chores on time without whining, then I can leave the house and go to the local stitching group. So I get to have fun sewing, get to enjoy a finished quilt some day, AND I get to go chat with the other ladies, and see what they're working on. Maybe learn something new. All because I got the chores done. I'm starting to see how it all fits together.
So ... I need a catchy phrase to explain it ... how about "count the many ways your chores bless you"?
This way of viewing things also helps me realize which activities are avoidance tactics ... like spending too much time on the computer, or looking through just one more catalog, when I really just ought to pitch it into the recycle bin. But some computer time is good. It can be fun and inspiring to chat with others online. So I'm finding a balance. I'm learning to see the difference between true fun and miserable procrastination.
I wouldn't mind trying your pumpkin bread recipe myself...
Big grin! :-)
Mary, To add another benefit to your yard work activity--I don't like yard work-or exercise--but I love reading. I attach my cd player (could be iPod) to my waistband and listen to audio books. Before I know it, I have been distracted enough to accomplish two hours of yard work.
As for a tweaked idea: I have taken labeling to the refrigerator and freezer. I label the shelves on the door (syrups, hot, savory, condiments) and freezer baskets in the freezer (chicken, beef, pork, seafood).
I want to label my fridge! I have threatened to do so w/ my Ptouch, and my DH said that if I did, he'd peel 'em off!
Pumpkin bread--let's see if I can remember it.
Makes 3 loaves, 350 degrees for an hour
Butter pans, line bottoms w/ foil or parchment, butter again, and dust pans w/ flour.
2 sticks butter
3 cups sugar (sometimes I use 2.5 cups)
(cream together)
4 eggs
1 tablespoon vanilla
(add and mix well)
1 lb. pumpkin
(add and mix well)
3 1/3 cups flour
X?? baking soda (I'm gonna have to look, I don't remember; 1 tablespoon, I think)
2 tsp cinnamon
1.5 tsp nutmeg
(combine together, then mix into the pumpkin mixture)
2/3 cup water (I think 2/3 cup; the water is the "secret ingredient")
(mix in slowly)
Bake. While it's baking:
1/3 stick butter
2 - 3 tablespoons maple syrup
(set in a ramekin next to the oven vent, so that the butter melts)
1/4 cup (or so) sugar
3 tsp (or so) cinnamon
(mix in a ramekin, adjusting proportion of cinnamon to have a reasonable cinnamon-sugar look)
When you take loaves out of oven, brush butter/syrup mixture over half of one, and IMMEDIATELY sprinkle sugar over the wet syrup so the sugar gets wet and "holds" the sugar in place. Repeat w/ all surfaces of the loaves. You can do a second coat if you like, but i've given up.
Let cool 10 minutes or so, then take out of pans (some sugar will fall off the top, so work over the sink or something).
no, no, no chocolate in the pumpkin bread! I forbid you to tweak my recipe that way! And if you do, you *may not* tell anybody you got it from me, you DO have to steal it, without attribution!
One nice thing about this recipe is, it DOES make 3 loaves. So you can make two to take (one to serve, and one for the pantry) and still have one for home. I'll get the two measurements I'm iffy about and post them.
Well...nobody asked about this so I hesitate to mention it... but what I like about a recipe that makes three loaves of pumpkin bread is slicing it, freezing the the slices, and sandwiching two of those with orange sherbet. (I get it in the ''box'' so I can slice it into the right size.) It's a wonderful summertime frozen treat. I'm making pumpkin bread this week just to make these; my sherbet has been holding in the freezer until I finally get around to it. Lately I've been trying to figure out what else I can freeze!
OK, orange sherbet maybe.
That's actually sort of intriguing. Maybe I'll steal that combo idea from you--but tweak it by servng it like birthday cake w/ ice cream.
And interesting about freezing before sandwiching. Do you eat it like a sandwich, or w/ a fork?
Note that my pumpkin bread is very soft. My mom's is stiffer (I liked it w/ peanut butter spread on it), so it might be better w/ ice-cream sandwiches.
Harumph! Chocolate chips are wonderful in pumpkin muffins, with brown sugar streusel on top, but my recipe doesn't call for maple syrup. Otherwise, it's just about the same as yours but for 2 dozen muffins. I was reluctant to try them, too, but they've become a family favorite. Maybe I'll try maple syrup next time.
Would ya mind sharing the muffin version? Are these standard sized muffins? I'll hafta get myself a second muffin tin! Being that it's so hot, I'd rather make muffins than loaves of pumpkin bread. And I have some pumkin in the freezer, that I grew and pureed myself.
Hoho HO!! Look what I just found in the Wayback Machine Archives. Further evidence in the case of the Great Ideas Theft.
[add a challenge/accountability feature?
Posted by Talley Sue-NYC () on Fri, Jun 23, 00 at 11:52
I visited one of those other sites, and found something I really like. But I don�t want to start hanging out there; I like it here at That Home Site! So, I figured, let�s just steal the idea!
The basic principle is that if we state our goals and check up on one another, we�ll be more motivated to actually achieve some organization in our homes. I have 2 ideas for an approach; tell me what you think about them]
Hmmmmmm... now what do you reckon, you the jurors, and the appeals judge? Do we hand out sentence of continued community service, in the form of daily compulsory postings by Talley Sue, on any topic of our choosing, or do we simply demand another YUMMY recipe from her!
Psssssssssst. Talley Sue? (whispering out the corner of my mouth) Any other good ideas you've found on the Ideas Blackmarket? I'll glady take the lot.
(Sorry, I couldn't resist that. It gave me a much needed giggle, Talley Sue. I needed it just to wear off the calories I gained simply from *reading* your pumkin cake recipe.) LOL
Albert Einstein said the secret to creativity was knowing how to hide your sources.
I rip off ideas every where I can. Those ideas are tweaked, modified, and morphed into workable creations for our lives.
Really, ripping off an idea is a high form of flattery.
One of my favorite organizing tips is to make 'centers.' In the kitchen, have a baking center with all you supplies and tools within easy reach. In the bathroom, have a basket for all your mani/pedi supplies. Easy to pull out, easy to put up. In the office....well, you can see how this works. Gather the things you use for a set of tasks and make a home for them together. I don't remember where I first read or heard this, but it has made my life better for over tweny years.
I've had this hand-written recipe for 15 years. The woman who gave it to me said she remembered her mom making them while she was growing up. She thought her mom sometimes used pecans instead of almonds, but I've never tried it. Logical combination, though. I tweaked it with the streusal topping.
Heat oven to 350º
3/4 C sliced or slivered unblanched almonds (1/2 Cup for the muffins, 1/4 Cup for Streusal)...I prefer slivered
1 2/3 C Flour
1 C granulated sugar
1 heaping tsp cinnamon
Scant 1/4 tsp nutmeg
1 tsp baking soda
1/4 tsp baking powder
1/4 tsp salt
2 large eggs
1 C plain pumpkin
1/2 C (1 stick) butter, melted
1 C chocolate chips
Here's the hard part. I don't have any amounts. I mix things together until they look right and are dry and crumbly enough. You'll get it right.
Cold Butter
Dark Brown Sugar
Dash of salt, a little cinnamon
1) Toast almonds on baking sheet for 5 minutes, until slightly browned. Be careful not to brown. Cool
2) Grease standard muffin tins or use liners
3) Mix dry ingredients together in large mixing bowl
4) In another small bowl, break eggs, add pumpkin and melted butter. Whisk until well blended
5) Stir in chips and almonds
6) Pour wet mixture over dry mixture; fold in with spatula until just moistened
7) Scoop into muffin tins. Sprinkle with streusal
8) Bake 20 to 25 minutes or until puffed and springy to touch. Cool on racks (or eat warm)
They're also great as mini-muffins - just the right size to pop in your mouth. At Thanksgiving I also make Sparkling Cranberry Muffins - excellent seasonal pairing for brunch or when we have our second go-round in the evening, after the main dinner. Dinner HAS to have buttermilk biscuits!
OMG, Lilydilly, I'm a career criminal! A recidivist (no, wait, you can only be a recidivist AFTER you've tried to reform). A habitual thief. A--dare I say it?--KLEPTO!
I was thinking of that stolen idea, when I was looking at the Wayback Machine archives.
The idea was, a monthly challenge. We'd pick one and start a single thread--July Junk Drawers--and everyone for whom that *was* a problem would tackle it. We'd brainstorm ideas (the people who already had organized junk drawers would give us their secrets), troubleshoot problems, and cheer each other on.
It was fun for awhile (until it ended up that few people were taking on that specific challenge were instead writing their own challenges, and then it got sort of diluted and turned into a different thing--tweaked)
OK, here are those pumpkin-bread ingredients again.
3 cups sugar
2 sticks (1 cup) butter
4 large eggs
1 can (1 lb.) pumpkin, or 2 cups
3 1/3 cups flour
2 teaspoons baking soda
1 1/2 teaspoons salt
2 teaspoons cinnamon
1 1/2 teaspoons nutmeg
2/3 cup water
I wonder what it would taste like if you grated a little orange zest into the pumpkin bread....or put orange juice in the glaze?
I've posted on the gardening side of GW for years before I discovered the Home Site. Gardeners are famous for "stealing" or should I say "borrowing" each others ideas! That's why we post them or frequent gardening magazines.
A few winters ago I was visiting historic Vizcaya in Miami Beach and loved the way they had pots of red pointsettas on each side of a long outdoor staircase. I repeated the look the following summer on my more modest outdoor steps to my house (not pointsettas, of course!) At another venue I saw a massive red flower garden with a corner of the same plants in bright purple. Now when I plant my hanging sacks I plant all red and leave the bottom two slots for bright purple. Same effect and I can't take my eyes off of it.
As for organizing, haven't we all ripped off the same ideas that are presented on HGTV and every magazine article and website regarding mail stations, zones in the kitchen, segregating the linen closet, putting out the toss, donate, throw boxes for cleaning clothes closets, etc. etc. Sometimes it just comes down to Just Do It!
I'm not very organized, so I can't steal or tweak any ideas there.... I can't wait to try the pumpkin bread..especially with the orange sherbet...
But I am a reasonably good musician, and where would we be without hearing some great piece of music and then recreating it for our own use?!!
I regularly hear medleys that send me scurrying for pencil and paper to write down what song goes into what song...I can write the segues myself...and presto, there is a new anthem!! Stealing...nah....imitating...yeah, that's it!! :^)
Then there are pictures of textile items that I need for my home....if I can see it, I can convince my ancient machine to sew it up (I show it pictures and feed it special oil :^)...see there, the machine did it all by itself :^)


text: Comments on: Engineering Fun Just another University Communications weblog 2012-04-21T21:48:24Z WordPress http://www.utexas.edu/inside_ut/lconf/2011/11/engineering-fun/feed/atom/ By: Liz Liz http://www.utexas.edu/inside_ut/lconf/?p=6522#comment-1353 2012-03-12T03:37:19Z 2012-03-12T03:37:19Z Wow! This looks complicated but also loads of fun. ]]> By: Jelisa Jelisa http://www.utexas.edu/inside_ut/lconf/?p=6522#comment-1135 2011-12-22T18:44:41Z 2011-12-22T18:44:41Z I love how much you love what you are studying. Engineers really do help change the world. ]]>

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Meet The Next Iron Chef Judges and Get a Sneak Peek of the First Episodeby Sarah De Heer in Shows, September 25th, 2012
A roster of acclaimed chefs will return for a second chance to become a member of the Iron Chef culinary society this fall, with the premiere of The Next Iron Chef: Redemption on Sunday, November 4 at 9 pm ET/PT. Earlier last month, FN Dish revealed the seven returning chefs and two newcomers:
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The tenth slot will go to the winner of a Web-exclusive competition taking place on FoodNetwork.com starting October 12. The four chefs taking part in the Web battle are: Duskie Estes and Robert Treviño, who have previously competed on The Next Iron Chef, and newcomers Lee Anne Wong and Madison Cowan.
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The newly crowned Iron Chef's first battle in Kitchen Stadium will premiere on Sunday, December 30 at 9pm ET/PT.
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As Election Day draws near, more and more yard signs are beginning to pop up on street corners and lawns across Lawrence County.
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im about to start my first batch i have everything sanitizing and im getting ready to start my boil. im brewing a red ale and it's an extract kit. i have read the directions many times and it never says anything about straining it when i pour it into the fermenter. do i just leave all the stuff in there? let me know quick thanks
I use a funnel with a strainer on top when I transfer the wort to the carboy...this catches the wort and break material. I got it for around $8 at my LHBS, but just about any funnel and strainer will work. It's the same one as sold on Austin Hombrew's site:FunnelStrainer
The fine mesh strainer is a bit small, but aerates the wort very well and has a tight enough mesh to keep out the hot/cold brew material.
It's your choice. Some just dump everything in, some use a strainer or collander that fits over their bucket....If you're using a carboy, you can get a funnel with a strainer built in.
I just started using a Nylon Paint Strainer Bag that fits in my bucket, sanitized of course.
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ok i guess i should have asked is straining something that i need to do? can i get by without straining this batch? i can get the strainer and stuff for the next batch just wondering if you really need to strain or if it's something that people prefer to do to make the beer clearer
It's not necessarily to make the beer clearer, but to remove particulate matter that may effect the taste of your beer. If you want to leave the hops in there, no worries. However, the hot and cold break material should be removed. That being said....either way you're going to have beer in the end, and damn good beer! RDWHAHB!
one last question when i boil all the stuff together for the hour do i want this covered or uncovered thanks guys
Definitely uncovered.
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I agree
Submitted by healthnut4freedom on Tue, 11/17/2009 - 01:29. Permalink
I would hope everyone who is on the DailyPaul will go sign it and send it on.
"Trust in the Lord with all thine heart; and lean not unto thine own understanding. In all thy ways acknowledge Him, and He shall direct thy paths." Proverbs 3:5,6
The lip of truth shall be established forever: but a lying tongue is but for a moment...Lying lips are abomination to the LORD: but they that deal truly are His delight. Prov 12:19,22


text:
V.20 No.52 |
The Daily Word in what happened in 2011, what's coming in 2012, a divorce over something that happened in the 1940's
By E.J. Maliskas [ Fri Dec 30 2011 9:19 AM ]
Beloved elderly man dies in the cold on his porch in La Mesilla, NM.
New state laws for 2012 bring about happy hour bans, fire-breathing regulations and more.
Canadian drug found successful in treating ovarian cancer.
99-year-old Italian man divorcing his wife of 77 years over her 1940's affair.
Anti-theft butt cheek recognition car seats.
Amazon, Facebook and Google consider a coordinated anti-SOPA blackout.
Target becomes target (hehe) for large public gathering of breast-feeding moms.
Too bad Christmas is over: I would have wanted a Batman iPod dock with built in taser.
Let's make some New Year's Eve resolutions.
Fox apologizes to Jews for Facebook poll on Jesus' death.
Words of comfort: Russia test fires long-range missile with new warhead.
Apparently Rihanna's forehead has its own Uncyclopedia page.
Thanks C!
Today's Events
Mark Twain Tonight! at Popejoy Hall
Celebrating his 90th birthday season, Hal Holbrook depicts the famous writer with words and humor.
ICUMDRUMS Cassette Release Party: Leeches of Lore • stoner rock, psychedelic • Italian Rats • DJ Rygar at Iron Haus
Make a Quilt Square at Cherry Hills LibraryMore Recommented Events ››
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Janigian Pages (19)
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John Michael Janigian
7/16/1920 - 1/10/2014
Resident of Belmont
A memorial service for John Michael Janigian, who died after a full life of 93 years, will be held on Sunday, March 2 at the VA Hospital Chapel in Palo Alto. "Johnny,' as everyone knew him, was a storyteller, a sailor, a Celtics fan, an airplane mechanic, a proud grandfather, and a man who left a legacy at an Armenian youth camp.
Born in Lynn, Mass. on July 16, 1920, the youngest child of Anna and Paul Janigian, Johnny graduated from Lynn Classical High School -- he was a proud Ram for a lifetime -- and went to work in the Massachusetts shipyards.
After joining the Navy during
World War II
, Johnny served as a seaman aboard the USS Lexington. He returned for a second stint during the
Korean War
, accumulating 30 years in active and reserve duty.
Johnny was one of the founders of Camp Haiastan, an Armenian youth camp in Franklin, Mass. He was an member of the Boston chapter of the Armenian Youth Federation, serving as a speedy guard on its basketball team.
In 1953, Johnny took a job as a mechanic with Capitol Airlines in Washington, D.C., which later merged with United Air Lines. In November that same year, he married Louise Paulian, who died last August.
In 1968, when United shifted some of its operations west, Johnny moved his family to Belmont, settling in the same house for more than 45 years. A gregarious man with a warehouse of stories, Johnny belonged to the Burlingame Masonic Lodge #400, Burlingame Scottish Rite, and the United Airlines Retirees Club.
Johnny died on Jan. 10, his natural hardiness finally succumbing to old age.
He is survived by his daughters Sarah (Scott) and Suzanne; and his son, George (Pam); niece Joanne Wortman, and sister-in-laws Diane Arey (Kenneth) and Gladys Paulian. He also is survived by grandchildren Becky (Joel), Ben, Rachel (Kevin), Zack, Jenny, Megan and John Michael, as well as great-grandsons Alec and Rory. His family thanks Cilda, Nelda, Lucy, and Lyn. Thanks also goes to the staff at Madera Villa for their loving care of Johnny in the last months.
The memorial service will begin at 2 p.m. at Building 101 of the hospital, 3801 Miranda Avenue in Palo Alto. In lieu of flowers, the family asks that donations be made to Camp Haiastan, P.O. Box C, Franklin, Mass. 02038 – Janigian Memorial Fund.
Published in San Jose Mercury News/San Mateo County Times on Feb. 23, 2014
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Sleep Inn
500 Veterans Blvd.
Bryson City, NC 28713
Phone: (828) 488-0326
Fax: (828) 488-4114
Wicked Weed
91 Biltmore Avenue
Asheville, NC 28801
+1 828 575 9599
Mo to We from 11:00 AM to 11:00 PM,Th to Sa from 11:00 AM to 02:00 AM,Su from 12:00 PM to 10:00 PMWhen the owners of Wicked Weed, the Guthy's and the Dickinson's started this brewpub, they wanted to revolutionize the concept of what people would know it to be. Within a short while of opening, the word about this place traveled through the city and its popularity quickly spread! The Wicked Weed restaurant is housed inside the same building as the brewery, downstairs in the basement. The menu features contemporary cuisine with international influences. Everything served here is crafted to go along perfectly with any of their beers. Guided tours are arranged for those who are interested in visiting the establishment.
Earn valuable points toward free nights.


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ACE Fit Share
Add these shoulder exercises into your regular workout routine and increase your upper body strength, while strengthening and stabilizing your shoulders. From the stability ball dumbbell press to the medicine ball push-up, these exercises are a great way to strengthen your deltoids, rotator cuff and trapezius muscles. Browse through our large collection of detailed tutorials and step-by-step demonstrations from today's leaders in the health fitness industry. For full workout routines featuring these shoulder exercises, visit our Workouts section.
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Have you ever wondered what health and fitness experts eat to fuel their bodies? From meals to snacks, top health and fitness experts offer insight into their dietary habits, nutrition tips and favorite healthy recipes.
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A novel process for nucleoside synthesis, which process comprises reacting the free sugar with heterocyclic bases in the presence of silylating agents in an inert solvent containing a Lewis acid.
1. A process for preparing nucleosides, which comprises reacting free sugars with hetero-cyclic bases in the presence of at least one silylating agent in an inert solvent containing a Lewis acid.
2. The process as claimed in claim 1, wherein the at least one silylating agent is selected from the group consisting of hexamethyldisilazane, trimethylchlorosilane, N,O-bis)trimethylsilyl) acetamide and N,O-bis(trimethylsilyl)acetamide.
3. process as claimed in claim 1, wherein one silylating agent is used.
4. A process as claimed in claim 1, wherein at least two different silylating agents are used.
5. A process as claimed in claim 1, wherein hexamethyldisilazane and trimethylchlorosilane are used as silylating agents.
6. A process as claimed in claim 1, wherein the Lewis acid is selected from the group consisting of trimethylsilyl triflate, trifluoromethanesulfonic acid, trimethylsilyl nonaflate, perfluorobutane sulfonic acid and Friedel-Crafts catalysts.
7. A process as claimed in claim 6, wherein the Friedel-Crafts catalyst is selected from the group consisting of SnCl4, SnCl2, TiCl4, BF3 -OEt2 and FeCl3.
8. A process as claimed in claim 1, wherein the inert solvent is selected from the group consisting of acetonitrile, nitromethane, 1,2-dichloroethane, CS2, chloroform, methylene chloride, tetrachloroethylene, and toluene.
9. A process as claimed in claim 1, wherein the reaction mixture is heated.
10. A process as claimed in claim 1, wherein the sugar is selected from the group consisting of D-ribose, D-xylose, D-glucose, and D-galactose.
11. A process as claimed in claim 1, wherein the hetero-cyclic base is selected from the group consisting of uracil, 6-azauracil, cytosine, N4 -acetylcytosine, thymine, 2-thiouracil, 6aza-2-thiouracil, N6 -benzoyladenine, N2 -acetylguanine and isobutyrylguanine.
The invention relates to a novel process for preparing nucleosides.
German Patent DBP 1919307 describes a process for preparing nucleosides, in which process O-acylated 1-O-acyl, 1-O-alkyl and 1-halo sugars are converted into the corresponding O-acylated nucleosides using silylated heterocyclic bases, such as uracil or 6-azauracil, in the presence of Friedel-Crafts catalysts such as SnCI4.
This process, involving the separate, prior silylation of the heterocyclic bases and their subsequent condensation with the abovementioned O-acylated 1-O-alkyl or 1-O-acyl sugars can, according to DOS 25 08 312, be simplified by carrying out the silylation of the heterocyclic bases and their condensation with O-acylated 1-O-alkyl or 1-O-acyl sugars in one step.
However, all these previous processes, which have been used widely in practice, employ O-acylated sugar derivatives which, like the very frequently used 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose, have to be prepared from D-ribose by a multistep synthesis.
It has now been found, surprisingly, that this multistep and elaborate conversion of the free sugars, such as D-ribose, into the corresponding O-acylated 1-O-alkyl or 1-O-acyl sugars, such as the already mentioned 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose, no longer applies, or becomes superfluous, if the free sugars, such as D-ribose or D-glucose, are persilylated, in the presence of the free bases, such as uracil, 6-azauracil, N6 -benzoyladenine or N2 -acetylguanine, in an inert solvent, with silylating agents, such as hexamethyldisilazane (HMDS) and trimethylchlorosilane (TCS), and a Lewis acid, such as trimethylsilyl triflate, trifluoromethanesulfonic acid, trimethylsilyl nonaflate, perfluorobutanesulfonic acid or SnCl4, is added either simultaneously or subsequently, resulting in the corresponding persilylated nucleosides being produced. These persilylated nucleosides can be converted into the desired free nucleosides by means of transsilylation using boiling methanol.
The invention consequently relates to a novel process for nucleoside synthesis, which process comprises reacting the free sugar with heterocyclic bases in the presence of silylating agents in an inert solvent containing a Lewis acid.
Following neutralization of the Lewis acid, the persilylated nucleosides which have been obtained are converted into the corresponding free nucleosides by means of transsilylation using excess methanol.
When the free sugars and the heterocyclic bases are persilylated with equivalent quantities of hexamethyldisilazane (HMDS) and trimethylchlorosilane (TCS) in boiling absolute acetonitrile, the ammonium chloride which forms sublimes in the reflux condenser and in this way is removed from the reaction mixture.
However, it is often expedient to silylate the mixture of sugar and heterocyclic base only with the calculated quantity of HMDS in the presence of catalytic quantities of TCS, with only ammonia being produced and escaping during heating in acetonitrile. When the reaction is conducted in this manner, the reaction mixture is not contaminated with NH4 Cl, and the Lewis acid can be added after the silylation is completed, with a clear solution being formed.
However, any other silylating agent, such as N,O-bis(trimethylsilyl)-acetamide or N,O-bis(trimethylsilyl)acetamide, can be used instead of HDMS/TCS. ##STR1##
Suitable free sugars are the sugars, such as D-ribose, D-xylose, D-glucose and D-galactose, inter alia, which are customarily used for nucleoside synthesis.
When free D-ribose reacts, the primary 5-hydroxyl group of the furanose form is first of all silylated selectively so that the persilylation results in virtually only persilylated D-ribofuranose, which, together with silylated heterocyclic bases, only gives rise to the corresponding natural D-ribofuranosyl nucleosides.
In individual cases, it can be advantageous, prior to the actual nucleoside synthesis, to selectively react the free primary hydroxyl groups of the sugars, such as the 5-hydroxyl group of D-ribose, with, for example, tert-butyldiphenylsilyl chloride, tert-butyldimethylsilyl chloride, thexyldimethylsilyl chloride or trityl chloride and then subsequently to persilylate these partially protected sugar derivatives with HMDS/TCS in the presence of the heterocyclic bases and convert them with Lewis acids into the corresponding persilylated nucleosides.
Uracil, 6-azauracil, cytosine, N4 -acetylcytosine, thymine, 2-thiouracil, 6-aza-2-thiouracil, N6 -benzoyladenine, N2 -acetylguanine or isobutyrylguanine, and also other deazapurines or azapurines, are preferred as heterocyclic bases.
Acetonitrile, nitromethane, 1,2-dichloroethane, CS2, chloroform, methylene chloride, tetrachloroethylene and toluene, in which solvents a homogeneous solution is usually produced when the mixture of free sugar and free heterocyclic base is persilylated, are used, in particular, as non-polar absolute solvents.
The previously mentioned Lewis acids, and also all the other Lewis acids which are known to be Friedel-Crafts catalysts, such as SnCl4, SnCl2, TiCl4, BF3 -OEt2, FeCl3, etc., are suitable for use as Lewis acids and lead to the formation of persilylated nucleosides.
During the working-up, further excess hexamethyldisilazane (HMDS) is added, as a base for neutralizing the Lewis acid, before the reaction mixture in acetonitrile (or another inert solvent) is evaporated. The remaining residue is then boiled, for the transsilylation, for approximately 1--3 h in excess methanol in the presence of fluoride ions (KF or tert-butylammonium fluoride hydrate), after which the mixture is evaporated.
The resulting free uridines are then filtered through a column of strongly basic exchangers such as Dowex 1 (OH form). When the column is eluted with dilute or concentrated ammonia, the neutral sugars which were produced during the nucleoside synthesis are eluted while the acidic uridines are only washed out of the column using 5% formic acid.
If they still do not crystallize, the crude uridines which have been obtained in this way are acetylated, for example with acetic anhydride/pyridine, and, after codistillation with xylene, filtered through a column of silica gel in a toluene/ethyl acetate system. After that, the acetates crystallize and, after recrystallization from methanol or ethanol, can be converted back into the pure, free nucleosides by treatment with methanolic ammonia.
The cytidines, adenosines and guanosines which are synthesized in an analogous manner are loaded onto a column of strongly acidic ion exchangers, such as Dowex 50 or IR-120 (H form), and eluted with increasing concentrations of ammonia after the oligosaccharides have been washed out. In the case of the guanosines, the ion exchanger has subsequently to be washed with dil. HCl.
If they do not crystallize, these prepurified cytidines, adenosines or guanosines are also acetylated with acetic anhydride/pyridine, with the acetates then being purified through a column of silica gel and the crystallized acetates being converted back into the free, pure nucleosides using methanolic ammonia.
In some cases, it is appropriate to dispense with the ion exchanger separation and to purify the crude product, after the transsilylation, directly by acetylation, chromatography on a silica gel column, recrystallization and, finally, hydrolysis with methanolic ammonia.
It is furthermore possible, particularly in the case of the adenosine syntheses, to treat the reducing oligosaccharides, which are produced as by-products, with hydrazine or hydrazine hydrate or semicarbazide in order to convert them into polar derivatives which can easily be separated off.
The following examples are intended to clarify the novel process.
5 mmol (0.56 g) of azauracil, 10 mmol (1.80 g) of D-glucose, 15 mmol (3.15 ml) of HMDS, 15 mmol (1.89 ml) of trimethylchlorosilane and 25 ml of acetonitrile are mixed and boiled at reflux for 5 hours. A further 5 mmol=1.05 ml of HMDS and 5 mmol (0.63 ml) of TCS are then added and the mixture is once again boiled for 5 hours. The condenser is changed and 7.5 mmol (1.12 g, 0.66 ml) of trifluoromethanesulfonic acid are added and the mixture is boiled at reflux for 3 hours. 5 mmol of HMDS are added and the mixture is concentrated; the residue is taken up in CH2 Cl2 and this solution is extracted by shaking with ice/NaHCO3, after which the organic phase is dried, filtered and concentrated. The residue, weighing 5.78 g, is taken up in MeOH and this solution is boiled at reflux and then concentrated; the residue (2.63 g) in H2 O is loaded onto an exchanger column containing 50 ml of Dowex 1 (OH form) 50-100 mesh. Elution with 2500 ml of 10% NH3 and 3000 ml of water yields 0.85 g of oligosaccharides, while elution with 750 ml of 5% formic acid yields 1.42 g of crude nucleoside. The latter is heated at 80� C. for 1 hour with 50 ml of pyridine and 25 ml of acetic anhydride. This mixture is subsequently concentrated and the residue evaporated 2= with xylene and then dissolved in 100 ml of CH2 CI2 ; this solution is extracted by shaking with 50 ml of saturated NaHCO3 /ice,→ emulsion, which is filtered through celite followed by washing with CH2 CI2 +H2 O. The phases are separated and the aqueous phase is back-extracted 3� with 50 ml of CH2 Cl2 in each case. The CH2 Cl2 phases are dried over Na2 SO4, filtered and concentrated. The crude product, of 1.65 g, is chromatographed through 200 g of silica gel (230-400 mesh) using toluene/ethyl acetate 1:1. After a 1000 ml forerun, 0.64 g, approx. 30%, of 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione is eluted in the following 1000 ml. Recrystallization from methanol results in pure tetraacetate having a melting point of 208�-210� C.
5 mmol (0.56 g) of azauracil, 5 mmol (0.75 g) of D-ribose, 14 mmol (2.92 ml) of HMDS, 14 mmol (1.77 ml) of trimethylchlorosilane and 50 ml of acetonitrile are mixed and boiled at reflux for 11/2hours. The mixture is subsequently cooled down to +10�, after which 7.5 mmol (0.66 ml) of trifluoromethanesulfonic acid are added and the mixture is boiled at reflux for 8 hours. After having been cooled down to 24�, it is concentrated on a rotary evaporator and the residue is boiled for 30 minutes with 50 ml of methanol. This mixture is concentrated in vacuo and the residue is then stirred at 60� for 2 hours with 20 ml of pyridine and 10 ml of acetic anhydride.
The mixture is subsequently concentrated and the residue is distilled 2� with 20 ml of xylene on each occasion. The residue is chromatographed on 100 g of silica gel (230-400 mesh) using toluene/ethyl acetate 1:1, yielding 0.9 g of crude azauridine triacetate.
Recrystallization from ethyl acetate/hexane yielded 0.62 g (=33.4%) of pure azauridine triacetate having a melting point of 102�-103�.
A mixture of 15 mmol (2.25 g) of dry D-ribose and 5 mmol (0.565 g) of 6-azauracil is silylated for 2 hours with 15 ml of HMDS and 0.1 ml of trimethylchlorosilane in 30 ml of boiling absolute acetonitrile. After concentrating by evaporation in vacuo, the residue is kept at 80�/1 mm for 2 hours and then dissolved in 40 ml of boiling absolute acetonitrile; 5.5 mmol (0.99 ml) of trimethylsilyl triflate in 10 ml of acetonitrile are then added at 80� C. and within the space of 45 minutes. After the mixture had been kept at 80� C. for 7 hours, 20 ml of a saturated, aqueous solution of NaHCO3 are added at 24� C. and the resulting dark-colored mixture is stirred at 24� C. for 4 hours. Following concentration, the dark-colored residue is extracted with 3�100 ml of boiling methanol and the extracts are concentrated. The residue is dissolved in approx. 10 ml of water and absorbed to approx. 20 g of SiO2, which is loaded onto a column of 200 g of SiO2 (previously treated for 4 hours with 25% NH3 (9:1) until a clear filtrate is obtained). Elution with ethanol/25% NH3 (9:1) first leads to 675 ml of eluate containing quantities of sugar and also traces of 6-azauracil. The following 650 ml yield 0.84 g (68.3%) of slightly colored crude 6-azauridine. The latter is treated in water with active charcoal and then crystallized from ethanol, yielding pure crystalline 6-azauridine (melting point 159�-161� C.).
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What is a "liveaboard" in SoCal?
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did a quick check on Chula Vista
It took some digging, but one of the newsletters from the Chula Vista Marina seems to show that they take a middle-of-the-road policy that would probably work for an occasional "stayaboard":
From their April 2010 newsletter:
<< snip:
Many of our boaters enjoy legal Liveaboard status and pay hard earned money for the privilege. Chula Vista Marina, like other marinas, is
limited in the number of total boats whom we can offer this status to.
It is disheartening to these Liveaboard Tenants when they see other
tenants enjoying this privilege as a Sneak- Aboard who is effectively
living aboard without the legal status and without paying.
Anyone who stays on their boat more than 3 nights a week is
considered to be living aboard.
If, occasionally, you plan to spend longer than 3 nights on board in any given week, just let the marina office know. We will be happy to issue you a Vacation Liveaboard Permit for a short stay at no cost to you.
Rates for a 35 footer seem to be $13/ft or $455.
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Propagating Spirea....
I don't know the names of the two types of spireas I have, but they are lime green and produce pink flowers and the other is darker green - Two of the lime green shrubs have a very nice rounded shape, but there are three shoots coming from the top of the shrub that I was going to trim. Then I realized that I read somewhere that spireas are easy to propagate. (Easy in a way that you just put the stem in the ground and water)... Can I do that?
Thanks - Carrie
I don't have a lot of experience, but I think you can propogate them by layering them. When I was checking up on a few that I am taking care of this year, I noticed that a branch had gotten covered by mulch from last year and when I pulled it out, there were roots growing where leaves used to be. Seems that the plant propogated itself! This link is for hydrangeas, but I think it should work for spirea as well!
Here is a link that might be useful: Layering instructions


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Genome Nation
March 27, 2015|
Researchers perform whole-genome sequencing on roughly 1 percent of the Icelandic population.
March 27, 2015|
Researchers perform whole-genome sequencing on roughly 1 percent of the Icelandic population.
March 26, 2015|
A novel Ebola vaccine being tested in China is safe and provokes a notable immune response in people, according to a Phase 1 trial.
March 25, 2015|
Methylation increases both the activity and instability of the signaling protein Notch.
March 23, 2015|
Online brain-training is gaining popularity, but so far little evidence exists to support claims of improved cognition.
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A census of adaptive immune system components in human skin reveals a variety of resident and traveling memory T cells.
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Latest analysis suggests the yeti is a known bear species, not the new, hybrid species suggested by a previous study.
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Foreign genes in animal genomes may be of bacterial or fungal origin, according to a new analysis.
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StartUpHire is the place to find Director, Customer Marketing jobs. Review the list of Director, Customer Marketing career opportunities to the left. These Director, Customer Marketing jobs represent some of the most rewarding careers available.
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Perfect opportunity for brand builders and product marketers with an entrepreneurial mindset who are excited about Consumer Products and getting in at the stealth stage of a venture-backed startup.2/20/2015 New York, NY Save This Job
The Director of Product Marketing will be instrumental in driving the company's global go-to-market planning and execution for this rapidly growing segment that is projected to eclipse 3 billion in the next four years. The ideal candidate will have3/19/2015 Santa Clara, CA Save This Job
Director, Product MarketingClick here to see all openings!Company Overview:Velocify is one of the fastest growing software-as-a-service companies in the country, providing the market-leading solution for intelligent sales automation and cloud-based telephony. Velocifyâs3/19/2015 El Segundo, CA Save This Job
Job ID: 16224 Job Location: Waltham MA Overview The Director of Product Marketing, Alternative Investments will be responsible will lead product marketing and business strategy development for Intralinks? alternative investments business, including private equity, hedge funds and2/22/2015 Waltham, MA Save This Job
Sr. Director Product Marketing JOB SUMMARY As the Senior Director of Product Marketing at Bridgelux, you will be a vital part of our fast growing company. You will be a part of a team of smart successful innovators who are passionate about successfully rolling out products to2/23/2015 Livermore, CA Save This Job
Marketing plays a critical role in generating demand for Medsphere's products and evangelizing our unique healthcare perspective. We currently have an opening for a motivated individual with strong leadership skills and a passion for innovation to lead our marketing team and help3/3/2015 San Francisco, CA Save This Job
As the Senior Director, Americas Marketing and Global Campaigns, you will report directly to our Chief Marketing officer and will be responsible for two critical marketing functions. First, this person will be responsible for lead generation strategy and execution in North2/14/2015 Newton, MA Save This Job
ON24 is the global leader in webinar-based marketing solutions that drive demand generation and customer engagement. Its patented cloud-based platform features an interactive and immersive user interface and industry-leading webinar analytics for events, campaigns and2/16/2015 San Francisco, CA Save This Job
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Are you interested in this job opening? Are you the perfect fit for our organization? Click on Apply Now! and we will walk you through our Online Application process. If you know of someone else who might be interested, please send this opportunity to a friend. TitleDirector,2/10/2015 San Jose, CA Save This Job
Director Customer Success Description The Director of Customer Success is responsible for all aspects of the global customer success experience and support programs and initiatives including strategies, best practices, escalation management, market surveys, systems and2/7/2015 Sunnyvale, CA Save This Job
Job ID: 14965 Job Location: Waltham MA Overview This highly visible role is responsible for the marketing strategy and campaign execution to grow awareness, generate demand and engagement, and build pipeline to support the rapid sales growth of a new solution, Intralinks VIA?, in2/22/2015 Waltham, MA Save This Job
Job ID: 14965 Job Location: Waltham MA Overview This highly visible role is responsible for the marketing strategy and campaign execution to grow awareness, generate demand and engagement, and build pipeline to support the rapid sales growth of a new solution, Intralinks VIA?, in2/22/2015 Waltham, MA Save This Job
The Director of Product Marketing will own product marketing strategy and execution for the AppNexus Advertisers & Agencies business unit. In this role, you will create marketing campaigns and go-to-market plans/strategies for new products and execute against those plans,1/31/2015 New York, NY Save This Job
More information about this job: The Director of product marketing is a global position leading a cross functional team responsible for the business success of the production genomics market, high-throughput applied genomics. The position is responsible for the entire product2/18/2015 South San Francisco, CA Save This Job
Director of Product Marketing or Sr. Product Marketing Manager, Enterprise Segment We?re disrupting IT infrastructure and rewriting the rules of cloud for enterprises, developers, and service providers, and we want your help. As a Product Marketing leader for the enterprise2/9/2015 Mountain View, CA Save This Job
Director of Product Marketing or Sr. Product Marketing Manager, Telco & Service Provider Segment (Mountain View, CA) We?re disrupting IT infrastructure and rewriting the rules of cloud for enterprises, developers, and service providers, and we want your help. As a Product2/9/2015 Mountain View, CA Save This Job
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By Catholic Online (NEWS CONSORTIUM)
3/10/2014 (1 year ago)
Catholic Online (www.catholic.org)
Fleeing religious violence, fewer than 1,000 Muslims remains out of the more than 100,000 Muslims who once lived in Bangui, the capital of the Central African Republic. United Nations aid chief Valerie Amos says the upheaval has been triggered by a campaign of violence by Christian militias.
By Catholic Online (NEWS CONSORTIUM)
Catholic Online (www.catholic.org)
3/10/2014 (1 year ago)
Published in Africa
Keywords: Central African Republic, aid, Muslims, refugees
LOS ANGELES, CA (Catholic Online) - Amos added that With 650,000 people already displaced by the religious conflict, the U.N has received far less than a fifth of the $551 million it asked for in December to provide food, medical care and shelter.
"The demography of CAR is changing, from a situation where you had 130,000 to 145,000 Muslims in Bangui, to where you had around 10,000 in December," Amos told a news conference. "That number we think has now gone down to 900. So we have to act very rapidly."
Saint Patrick's Day is coming -- go here --
The Security Council last week discussed a proposal for a nearly 12,000-strong peacekeeping force to stop the killing -- but has reached no decision. The United States and Britain are concerned by the cost of a large force, while France is expected to submit a draft resolution in the coming weeks.
France has deployed 2,000 troops to support a 6,000-strong African Union peacekeeping mission in the country of 4.5 million people that has failed to contain the fighting.
"More troops are needed now to restore security and stabilize the country," Amos warned. The deployment of a U.N. peacekeeping force would take at least six months.
Most of the Muslims, estimated to be 290,000 strong, have fled across the border into neighboring countries. In the west of the Central African Republic, many towns have lost their entire Muslim populations following a mass exodus.
Tens of thousands have been killed since the Seleka, a coalition of mostly Muslim northern rebels, seized power a year ago, according to Human Rights Watch. Many of its fighters embarked on a 10-month campaign of looting, torture and murder.
Christian "anti-Balaka" militias have stepped up reprisals against Muslims, with the departure of Seleka leader and interim president Michel Djotodia in January.
"We have made suggestions, for example that we should be perhaps targeting three or four cities to try to stabilize those cities, to try to make sure that they retain a mixed population," Amos told a news conference in Geneva.
Aid workers fear malaria and dysentery in makeshift camps with the onset of the six-month-long rainy season due to begin in April. The sprawling settlement of cardboard shacks and tarpaulins beside Bangui airport, home to around 70,000 people, is just one example of the dire situation many face.
Efforts to bring humanitarian supplies to a desperate population are being complicated by attacks on aid distribution sites by armed groups as well as robberies and looting, Doctors Without Frontiers says.
St. Ann
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St. Francis of Assisi
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St. Brigid of Ireland
St. Florian
St. Jude
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St. Joseph of Cupertino
St. Isidore the Farmer
St. John the Baptist
By Catholic Online (NEWS CONSORTIUM)
Taking a sickening cue from Islamic State, the Somali extremist group Al Shabaab has now filmed civilians, young men being forced into the sea and shot to death in a hail of gunfire. Entitled "In Remembrance 2," the video shows Al-Shabaab coldly executing their ... continue reading
By Emma Batha, Thomson Reuters Foundation
Two former child brides have taken Zimbabwe's government to court in a groundbreaking bid to get child marriages declared illegal and unconstitutional. LONDON (Thomson Reuters Foundation) - Loveness Mudzuru and Ruvimbo Tsopodzi say child marriage, which is rife ... continue reading
By Katie Ngyuen, Thomson Reuters Foundation
Girls as young as 18 months are being raped and left with horrific injuries in eastern Congo after being stolen from their homes at night, a charity said on Tuesday. LONDON (Thomson Reuters Foundation) - The children, many of them under five, have been treated at ... continue reading
By Catholic Online (NEWS CONSORTIUM)
Speaking at panel, "Sensitivity Rather Than Sensationalism: Western Media Coverage of Human Rights and Religious Issues in the Middle East," Bishop Anba Angaelos, general bishop of the Coptic Orthodox Church of Alexandria, Egypt for the U.K. spoke out on the ... continue reading
By Abigail James (NEWS CONSORTIUM)
Men dressed in military garb entered a Tunisia museum, opened fire and killed 19 people while taking hostages, ending in a firefight between security forces and the gunmen. The current death count stands at 21. According to Mohamed Ali Aroui, an Interior Ministry ... continue reading
By Kaci Racelma (Catholic Online)
Libyan terrorist groups are wasting no time opening a new chapter of violence, seizing two oil fields earlier this month before taking nine foreigners hostage. LOS ANGELES, CA (Catholic Online) - Islamic militants took Al-Bahi and Al-Mabrouk oilfields on March 3, ... continue reading
By Catholic Online (NEWS CONSORTIUM)
Evil compliments evil, evidently. Nigerian terrorist group Boko Haram has officially pledged their allegiance to Islamic State on an online audio recording posted to the Internet this past weekend. The message came from Boko Haram's alleged leader, Abubakar ... continue reading
By Catholic Online (NEWS CONSORTIUM)
Coptic monks in Egypt are facing death by bulldozer as road workers chanting "Allah Akbar!" plan to bulldoze an ancient Christian site to construct a road. To protest the project, monks have laid before the bulldozers. So far, no lives have been lost, but a great risk ... continue reading
By Joseph D'Urso, Thomson Reuters Foundation
Almost 30 countries around the world are "highly vulnerable" to an Ebola-style epidemic, with Somalia, Chad, Nigeria, Afghanistan and Haiti most at risk, a major charity said on Tuesday. LONDON (Thomson Reuters Foundation) - An increasingly mobile global population ... continue reading
By Catholic Online (NEWS CONSORTIUM)
Suspected of being a suicide bomber with Boko Haram, a teenage girl was beaten to death, and then set on fire in a Nigerian vegetable market. A second suspected teenage girl, also accused of being a suicide bomber was later arrested at the Muda Lawal market, ... continue reading


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Registration underway for Get Fit GP Run for Shelter 5K and "Chase the Chiefs" 1-Mile Fun Run on 4/25/15
MORE: Get Fit GP Calendar
March is a great time to give your diet a makeover! The variety of fresh foods is increasing at local grocery stores and farmers markets.
The internet makes trying new foods easy with numerous recipes available, as well as how-to resources on planting, harvesting and preparing your produce.
The USDA Choose MyPlate describes a healthy diet as one with a focus on vegetables, fruits, fat-free or low-fat milk and milk products, as well as whole grains.
MyPlate food guidelines suggest more lean meat consumption, nuts, eggs, beans, fish and poultry; and a diet that is low in trans fats, saturated fats, cholesterol, added sugars and salt. For more information, check out 10 Tips for a Great Plate.
Experts agree that eating a variety of fruit and vegetables, grains, and legumes (dried peas and beans) helps to reduce your risk of cancer, heart disease, diabetes and other chronic diseases.
The U.S. Department of Agriculture (USDA) and the World Health Organization (WHO) recommend eating at least five servings a day of fruits and vegetables.
Eating locally grown foods is a great way to ensure freshness and nutritional value of your food with less environmental impact.
A colorful plate is one indication of a healthy diet. By eating fruits and vegetables of different colors you get a wider range of phytochemicals. Red, orange/yellow, green, blue/ purple, and neutral colored foods all have specific properties to improve health and fight off disease.
For freshness and flavor, nothing beats a vegetable garden. It's also a great way to get exercise and can be fun and educational for kids. Choose varieties that fit the space you have. You can grow many varieties in containers or indoors.
Grand Prairie Library offers many books on nutrition including the following:
Spanish Language Books
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I miss my kochi 240 ktip KU gyuto. So until Jon at JKI gets them restocked, i thought why not ask kkf? I had her in v2 but curious about the SS line.
There can be significant variation between knives, even from a single maker in my experience.
My favourite knives have come from from Yoshikane,
First: Sorry for some seemingly random threads I have started here ... new and learning.
The more I read ... and I am reading quite a
hahahahaha wow! Jon, your the man! As i was reading about the sharpening, i think i re read in disbelief over and over. That was a good one
Yeah it's a super cool looking knife


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Country/Date of Origin: Ireland/100 BC
One of the oldest of purebred dogs, the Irish Wolfhound was the hunting dog of the Celtic people. It followed them on their migration across Europe and became the dominant coursing hound in Ireland where it was so good at its job it exterminated the last wolf in the mid 1800s, almost destroying itself with it. The deer hunters were exclusively the possession of the aristocracy who, of course, owned the deer in Ireland and England.
Combining great speed and strength, the Irish Wolfhound found a place as a hunter's companion on the American and Canadian frontier and even later in Australia.
About This Breed:
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AKC Group: Hound
Breed Club: The Irish Wolfhound Club of America, Inc.
Rescue Club: The Irish Wolfhound Club of America, Inc. Rescue
Body Type:
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text:
The Top 100 Inspirational Books: 80 - 61
68 - You Are Special
I was lucky enough to travel to Ghana in 2007 as part of an American Christian ministry team. We were invited by the Lutheran Church of Ghana and traveled throughout the country to schools, churches, and villages. One of the special memories that remains with me is when we read You Are Special to the local children while we were in a small town. This book, written by Max Lucado, tells the heartwarming story of Eli the Woodcarver who loves Punchinello – an ugly and unique character who doesn't always feel special or loved.
The message of this book - that no matter what others think of you, you are still loved by God – is such a powerful message to share, especially with children. It was a privilege to use this book to help Ghanaian children know that they are beautiful the way they are, and that God loves them very much.
~ Jana Melpolder
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