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PASADENA, Calif.—The Ralph M. Parsons Foundation has pledged $1 million to the California Institute of Technology toward construction of a new building for chemistry and chemical engineering positioned to be the centerpiece of the Division of Chemistry and Chemical Engineering's plan for the future.
"I am delighted to thank the foundation for their commitment," said Jean-Lou Chameau, president of Caltech. "This grant represents a key component in moving a project critical to Caltech's future forward."
The new facility will be especially important in the Division's plans to further integrate teaching and research initiatives in chemistry and chemical engineering with other areas of science and engineering. The building is being named the Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering in recognition of a lead commitment toward the $35 million project from the three-degree alumnus (BS'44, MS'46, PhD'49) and his wife.
With approximately 60,000 square feet divided among three levels above ground and one basement level, the building will house seven research laboratories, one classroom and three smaller conference rooms. The Schlinger Laboratory will face San Pasqual Walk between the Noyes Laboratory of Chemical Physics and the Beckman Laboratories of Behavioral Biology, and will complete a cluster of buildings with complementary research activities.
Once constructed, the Schlinger Laboratory will support several research groups involved in projects aimed at new and synthetically useful chemical transformations with novel catalysts, the synthesis of complex organic molecules important in biology and medicine, and custom-designed polymers and nanometer-scale structures. Current plans call for the third floor to be committed entirely to organic synthesis.
The facility will house a world-class center for catalysis and chemical synthesis to be led by Nobel Laureate Robert Grubbs, the Victor and Elizabeth Atkins Professor of Chemistry. Increased space will also allow the division to bring in additional faculty who will take research in new directions, including the synthesis of pharmaceuticals and advanced materials, and the creation of alternative energy technologies.
Other scientists to move into the Schlinger Laboratory will expand our understanding of the chemistry of the atmosphere and the nature of atmospheric changes and how these changes influence the biology of the planet-an essential step in predicting how the global climate will evolve in the next few decades.
Through the years, the Parsons Foundation has provided exceptional support for both research and education at Caltech. The foundation was established in 1961 by the late Ralph M. Parsons, founder of the international engineering and construction firm that bears his name. The foundation, since 1974 a separate, free-standing, charitable organization independent of the corporation, awards grants focusing on the areas of higher education, social-impact programs, health, and civic and cultural endeavors.
PASADENA, Calif.—In the late 1960s, the memorable advice given to a certain graduate of movie fame was to go into plastics. Forty years later, Caltech chemical engineering professor Julia Kornfield would like to add the word "shish-kebabs."
Shish-kebabs are beautiful, tiny structures that can form when polymers crystallize during flow. When magnified a million times they resemble a skewer running through a stack of bell peppers. Inside plastics, they make car body panels stiff and carpet fibers strong.
Shish-kebabs are responsible for the product's nice glossy finish and the hardness, but they are not without their problems. They might help you to resist a scratch, but they might also cause a layer to peel off. And that's why people want to control them.
Now, Kornfield and Yoshinobu Nozue at Sumitomo have led a team that has uncovered certain properties of shish-kebabs that should lead to improved materials in the most widely used plastics. The researchers are reporting their results in the May 18 issue of the journal Science.
"Our discovery is pertinent to the relatively strong and stiff plastics," says Kornfield. "For example, it will allow manufacturers to make polymers for complex and beautifully shaped body panels with equal or better quality than currently available-and cheaper and faster."
Shish-kebabs are made of polymers known as polyolefins, which make up half of all plastics used-over 100 million tons per year. In addition to being used for car parts, polyolefins are also used to make pipes, wire, cable, carpets, fabrics, disposable syringes, and many other things.
Polyolefins are useful because manufacturers can custom-design their properties, Kornfield explains. By varying the degree of crystallinity and the way the crystals come together, polyolefins can be altered so that they are as hard as steel or as soft as a rubber band.
"The plastics industry can tailor-make molecular distributions, but we don't know how to manipulate them," Kornfield explains. "This discovery opens up a whole new neck of the woods that people didn't know they could explore, and they'll be able to create combinations of properties you couldn't get before."
Much as an inspiring leader can influence the action of thousands, the researchers discovered, some molecules (especially long ones) can marshal many others to create the shish, which then direct the formation of kebabs. This knowledge will allow for greater control of the creation process itself.
"In other words, you could make things by injection molding that you couldn't make before, and injection molding is a very cheap, fast process-you can pop a plastic bumper for an automobile out of its mold in a couple of minutes. So you bring down the cost of manufacturing and at the same time increase the throughput."
The lead author of the paper is Shuichi Kimata, a former postdoctoral researcher in Kornfield's Caltech lab. He played a central role linking Kornfield's group at Caltech with Yoshinobu Nozue's group at Sumitomo and collaborators at the University of Tokyo.
The title of the Science paper is "Molecular Basis of the Shish-Kebab Morphology in Polymer Crystallization."
The grant will establish a Center for Catalysis and Chemical Synthesis (3CS), with facilities operated by the Division of Chemistry and Chemical Engineering. The center aims to speed the invention of new catalytic reactions, much as improved robotics accelerated the Human Genome Project.
Caltech chemists have proposed several major projects that could benefit from faster experimentation. According to Victor and Elizabeth Atkins Professor of Chemistry Robert Grubbs, founding director of the center and 2005 Nobel laureate in chemistry, projects will include the development and production of medicines, new reactions for making industrial products out of biomass, and the catalytic conversion of sunlight energy into stored chemical fuels.
"The increasing demands on chemistry resulting from new drug targets from the Human Genome Project and critical environmental requirements of chemical processes require us to develop more efficient techniques for chemical discovery," Grubbs says.
Bringing together scientists from a wide variety of disciplines, the center will create two new facilities, which will share resources to promote both the rapid discovery of chemical reactions and the production of focused molecular libraries.
Like test-kitchen chefs trying variations to perfect a recipe, robotics and instruments at the facility for catalyst and reaction invention will allow investigators to rapidly survey a wide array of reaction parameters. The conventional approach is labor intensive, taking researchers' time away from the conceptual or innovative aspects of their work, so researchers have often chosen familiar syntheses rather than taking the chances that could lead to new discoveries. By making experimentation easier, the center will facilitate the exploration of higher-risk strategies.
Many of the same techniques that are used for developing new reactions can also be used to synthesize molecular libraries. Researchers use libraries for an efficient and cost-effective "shotgun" approach, performing many simultaneous tests to see what works. Yet large existing libraries are not ideal for particular applications. The focused library facility will make it easier and faster to generate small libraries designed for specific targets, allowing researchers to optimize them efficiently for their selected applications.
The Gordon and Betty Moore Foundation was established in 2000 and seeks to develop outcome-based projects that will improve the quality of life for future generations. It has organized the majority of its grant making around large-scale initiatives and concentrates funding in three program areas: environmental conservation, science, and the San Francisco Bay Area.
The foundation's $300 million California Institute of Technology commitment, combined with an additional personal gift of $300 million from Gordon and Betty Moore, make Caltech the recipient of the largest donation ever made to an institution of higher learning. Gordon Moore is an alumnus (PhD '54) and trustee of the Institute.
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PASADENA, Calif.—Don't throw away your laptop yet, but there's a promising new high-tech invention being announced this week. Researchers have created a memory circuit the size of a white blood cell that has enough capacity to store the Declaration of Independence and have space left over. With 160 kilobits of capacity, it's the densest memory circuit ever fabricated.
Announcing the achievement in the January 25 issue of the journal Nature, the team led by chemistry professor James Heath of the California Institute of Technology says that the memory circuit is a milestone in manufacturing, even if it's not anywhere near readiness for the market.
"It's the sort of device that Intel would contemplate making in the year 2020," says Heath, who is the Gilloon Professor at Caltech. "But at the moment it furthers our goal of learning how to manufacture functional electronic circuitry at molecular dimensions."
The 2020 date assumes the validity of Moore's law, which states that the complexity of an integrated circuit will typically double every year. Current memory-cell size is .0408 square micrometers, so Moore's law assumes that the electronics industry will achieve a device density comparable to the Heath team's memory circuit in about 13 years.
However, the Caltech-UCLA team points out in their Nature article that manufacturers can see no clear way at present of extending this miniaturization beyond the year 2013. The new approach of the Heath team, therefore, will show the potential for making integrated circuits at smaller and smaller dimensions.
"Whether it's actually possible to get this new memory circuit into a laptop, I don't know," says Heath. "But we have time."
The 160,000 memory bits are arranged like a large tic-tac-toe board: 400 silicon wires crossed by 400 titanium wires, with a layer of molecular switches sandwiched between the crossing wires. Each wire crossing defines a bit, and a single bit is only 15 nanometers wide, or about one ten-thousandth the diameter of a human hair. By contrast, the most dense memory devices currently available are approximately 140 nanometers in width.
The molecular switches, called [2]rotaxanes, comprise two interlocking components—a molecular ring encircling a dumbbell-shaped molecule—that together are similar to a wedding band on a finger. When the molecular switch is electronically triggered, the ring slides between two locations on the dumbbell. Switching, then, arises from the different conductivities of the molecular switch with respect to the ring position.
Heath's group manufactured the memory circuit in a clean-room facility in their labs at Caltech, and the molecular switches were prepared by J. Fraser Stoddart, who holds UCLA's Fred Kavli Chair in Nanosystems Sciences, and his group.
The circuit has a bit density of 100 gigabit per square centimeter, which Heath's fellow lead author Jonathan Green says sets the record for integration density in a man-made object.
"We showed we can increase the density to nearly 1,000 gigabits per square centimeter, but, beyond that, there is almost no point, because you begin to run out of molecules," says Green, a Caltech graduate student in chemistry and applied physics.
The capability to manufacture electronic circuitry at such extreme dimensions opens up a host of new applications, ranging from extremely sensitive chemical and biological sensors, energy-efficient logic circuits, and a class of high-performance energy-conversion materials known as thermoelectrics.
The other lead author of the paper is Jang Wook Choi, a graduate student in chemical engineering at Caltech. The other authors are Akram Boukai, Yuri Bunimovich, Ezekiel Johnston-Halperin, Erica DeIonno, Yi Luo, Bonnie Sheriff, Ke Xu, and Young Shik Shin, all graduate students in Caltech's Division of Chemistry and Chemical Engineering, and Hsian-Rong Tseng and Stoddart, both of UCLA.
PASADENA, Calif.—Carbon nanotubes are tiny garden-hose-like hollow tubes that have considerable promise for future applications such as nano-sized plumbing and nanolithography, and for the creation of numerous tiny devices such as mass sensors and actuators. Such applications require improved understanding of the mechanical properties of carbon nanotubes. Previous studies pointed out that carbon nanotubes behave like macroscopic elastic hoses similar to garden hoses made of rubber.
Now, researchers at the California Institute of Technology have discovered through computer simulations that the bending of carbon nanotubes occurs differently from that of their macroscopic counterparts in significant ways. Rather than buckling immediately and squashing the hollow inner channel, the results show, the cross-section can be gradually flattened—a finding that could lead to applications in controlling the flow of fluids through real carbon nanotubes. The results are published in the current issue of the journal Physical Review Letters.
According to Konstantinos Giapis, an associate professor of chemical engineering at Caltech and lead author of the paper, the size of nanotubes that he and postdoctoral scholar Oleksandr Kutana used for the simulation are between two and seven nanometers—or less than one-ten-thousandth the diameter of a human hair. Previous studies had focused on smaller nanotubes.
When the slightly larger nanotubes are "bent" sufficiently in the simulation, Giapis explains, the walls meet when the two sides are brought close enough together, and an atomic attraction known as the van der Waals force causes the atoms of each side of the wall to stick together. This effectively clamps off the nanotube, stopping any flow of material within it until the tube is re-straightened.
"The results show that there is an intermediate regime where you can adjust the nanotube cross-section to your liking," Giapis says. "This intermediate bending regime is important for nanofluidics."
Unlike a garden hose, however, nanotubes are tiny enough to feel forces that are inconsequential in the macroscopic world. Whereas the van der Waals force is much too weak to cause the walls of a garden hose to stick together, the force should be sufficient at the microscopic level to act as a "glue" to hold the walls of nanotubes together even after the load has been partially removed.
The end result, Giapis explains, is a new understanding of how it may be possible to control microflow in the emerging world of nanotechnology. "The initial study was to understand how nanotubes bend and how their bending differs from that of macroscopic objects, but there are also practical applications.
"For future microfluidic devices, you're going to need valves," he says. These devices could include everything from pharmaceutical-delivery systems to nano-inkjet printers.
The article is available on-line at http://link.aps.org/abstract/PRL/v97/e245501.
PASADENA, Calif.—Nelson J. Leonard, one of the most important chemists of the 20th century, died Monday, October 9, at his home in Pasadena, California. He was 90.
Leonard was born on September 1, 1916, in Newark, New Jersey, and attended Lehigh University in Bethlehem, Pennsylvania, before moving to Oxford University as a Rhodes Scholar. The beginning of World War II in September 1939 forced Leonard's return to the United States.
Upon his return, Leonard continued his graduate education in chemistry, concluding with a Ph.D. in 1942 from Columbia University. His research, which focused on structure establishment and partial synthesis of alstonine, a naturally occurring antimalarial compound, was performed under the direction of Robert C. Elderfield.
A postdoctoral research assistantship brought Leonard to the University of Illinois Urbana-Champaign, where he worked with professor Roger Adams on Senecio alkaloids. Teaching duties were added to his research responsibilities in 1943, and his students eventually included U.S. Navy and U.S. Army units passing through the University of Illinois. He joined a team led by professors Charles C. Price III and Harold R. Snyder engaged in research to forward the synthesis and production of the important antimalarial drug chloroquine in time for its use in the Pacific theater.
At the end of the war, during 1945 and 1946, Leonard served as a scientific consultant and special investigator in the Field Intelligence Agency Technical (FIAT), U.S. Army and U.S. Department of Commerce, European Theater. He then returned to the University of Illinois and remained on the teaching staff until his retirement in 1986. Beginning in 1992, he held the position of faculty associate in chemistry at the California Institute of Technology.
From 1943 until 1955, Leonard combined his academic work in chemistry with a flourishing musical career, as he performed as a bass-baritone soloist in choral works with the Chicago, Cleveland, and St. Louis symphony orchestras. When in 1955 Leonard was elected to membership in the National Academy of Sciences, he felt that if his peers had chosen to recognize him as a chemist, then he had "better do something about it." The heavy professional demands of chemistry would take precedence, and there would be no more singing performances.
In collaboration with professor Folke Skoog, a plant physiologist at the University of Wisconsin, Leonard carried out extensive investigations of organic compounds that initiate plant, flower, and tree growth from tissue culture, technology that is central to horticultural and agricultural development. His techniques for derivatization of nucleosides, nucleotides, and coenzymes, and to prepare fluorescent probes, placed him among the most often quoted scientists.
Over the course of his career, he published more than 400 scientific papers and trained more than 200 Ph.D. students and postdoctoral scholars. In addition to his early election to membership in the National Academy of Sciences, Leonard was a fellow of the American Academy of Arts and Sciences and a member of the American Philosophical Society. His research distinctions included the prestigious Roger Adams Award in Organic Chemistry (1981) and Arthur C. Cope Scholar Award (1995) of the American Chemical Society.
Chemistry was not the only part of Leonard's life that was interrupted by the war. Through family connections, he had met and fallen in love with Louise Cornelie Vermey of the Netherlands. They were engaged, but were not able to see each other again until the end of the war in 1945, and were unable to arrange for her journey to the United States and marriage until 1947. She died in 1987.
Leonard is survived by his wife, Peggy Phelps, of Pasadena; his daughter, Marcia, of Maplewood, New Jersey; his sons Kenneth, of Agoura Hills, James, of Olympia, Washington, and David, of Seattle, Washington; and seven grandchildren.
A memorial service is planned for 3 p.m. Monday, November 13, at All Saints Church, 132 North Euclid Avenue, Pasadena. Memorial donations should be made to the Nelson J. Leonard Fund at the Pasadena Symphony.
PASADENA, Calif.—Jacqueline Barton, the Arthur and Marian Hanisch Memorial Professor and professor of chemistry at the California Institute of Technology, has been named the 2006 recipient of the Willard Gibbs Award. The honor was bestowed on Barton at a special award dinner hosted by the Chicago section of the American Chemical Society on May 12 in Des Plaines, Illinois.
Barton becomes the second woman to receive the honor in its 95-year history, the first having been Marie Curie in 1921. Barton and her husband, Peter Dervan (the Bren Professor of Chemistry at Caltech), also become the first husband and wife to have won the Gibbs Award.
Established in 1911, the Gibbs Award is presented annually to a researcher who pioneers new avenues of investigation in chemistry. Barton is cited for her "major impact on the understanding of the molecular chemistry of DNA and its relevance to the development of a variety of diseases and inherited abnormalities.
"Her work is elegant, vitally important work that has been widely recognized for its novelty and significance," the citation continues. "Professor Barton pioneered the application of transition metal complexes as tools to probe recognition and reactions of double helical DNA. This work provides a new approach to the study of DNA structure and dynamics. She has carried out important studies to examine the transport of electric charge through DNA, establishing reactions by which DNA can be damaged from a distance as well as how lesions in DNA can be repaired, locally or at distant sites on the DNA helix. Her work also provides the basis for sensitive diagnostic sensors for DNA."
A New York native, Barton earned her bachelor's degree, summa cum laude, at Barnard College in 1974 and her doctorate in inorganic chemistry at Columbia University in 1978. After several years on the faculty at Columbia, she joined the Caltech faculty in 1989.
She is the recipient of numerous awards, including a MacArthur Foundation Fellowship in 1991, the 1985 Alan T. Waterman Award of the National Science Foundation, which recognizes an outstanding young science or engineering researcher, and the 1988 American Chemical Society Award in Pure Chemistry. She was elected a fellow of the American Academy of Arts and Sciences in 1991, fellow of the American Philosophical Society in 2000, and in 2002 Barton was elected to the National Academy of Sciences.
Other American Chemical Society awards include the 1987 Eli Lilly Award in Biological Chemistry, the 1992 Garvan Medal, the 1997 Nichols Medal, and the 2003 Breslow Award. She has also received the Columbia University Medal of Excellence in 1992, the Mayor of New York's Award in Science and Technology in 1988, the Paul Karrer Gold Medal (University of Zurich) in 1996, and the Weizmann Woman & Science Award in 1998. She has received several honorary degrees, including last year a Doctor of Science from Yale University.
PASADENA, Calif.—An ongoing challenge in biochemistry is getting a handle on protein folding-that is, the way that DNA sequences determine the unique structure and functions of proteins, which then act as "biology's workhorses." Gaining mastery over the construction of proteins will someday lead to breakthroughs in medicine and pharmaceuticals.
One method for studying the determinants of a protein's structure and function is to analyze numerous proteins with similar structure and function-a protein family-as a group. By studying families of natural proteins, researchers can tease out many of the fundamental interactions responsible for a given property.
A team of chemical engineers, chemists, and biochemists at the California Institute of Technology have now managed to create a large number of proteins that are very different in sequence yet retain similar structures. The scientists use computational tools to analyze protein structures and pinpoint locations at which they can break them apart and then reassemble them, like Lego pieces. Each new construction is a protein with new functions and new potential enzyme actions.
Reporting in the April 10 issue of the Public Library of Science Biology, Caltech graduate student Christopher Otey and his colleagues show that they have successfully taken three proteins from nature, broken them each into eight pieces, and successfully reconstructed the pieces to form many new proteins. According to Otey, the potential number of new proteins from just three proteins is three raised to the eighth power, or 6,561, assuming that each protein is divided into eight segments. "The result is an artificial protein family," Otey explains. "In this single experiment, we've been able to make about 3,000 new proteins."
About half of the 6,561 proteins are viable, having an average of about 72 sequence changes. "The benefit is that you can use the new proteins and new sequence information to learn new things about the original proteins," Otey adds. "For example, if a certain protein function depends on one amino acid that never changes, then the protein apparently must have that particular amino acid."
The proteins the team has been using are called cytochromes P450, which play critical roles in drug metabolism, hormone synthesis, and the biodegradation of many chemicals. Using computational techniques, the researchers predict how to break up this roughly 460-amino-acid protein into individual blocks of about 60 to 70 amino acids.
Otey says that this is an important result when considering the old-fashioned way of obtaining protein sequences. Whereas, over the past 40 years, researchers have fully determined 4,500 natural P450 sequences, the Caltech team required only a few months to create 3,000 additional new sequences.
"Our goal in the lab is to be able to create a bunch of proteins very quickly," Otey says, "but the overall benefit is an understanding of what makes a protein do what it does and potentially the production of new pharmaceuticals, new antibiotics, and such.
"During evolution, nature conserves protein structure, which we do with the computational tools, while changing protein sequence which can lead to proteins with new functions," he says. "And new functions can ultimately result in new treatments."
In addition to Otey, the other authors of the paper are Frances Arnold (the corresponding author), who is Dickinson Professor of Chemical Engineering and Biochemistry at Caltech, and Otey's supervising professor; Marco Landwehr, a postdoctoral scholar in biochemistry; Jeffrey B. Endelman, a recently graduated Caltech graduate student in bioengineering; Jesse Bloom, a graduate student in chemistry; and Kaori Hiraga, a Caltech postdoctoral scholar who is now at the New York State Department of Health.
The title of the article is "Structure-Guided Recombination Creates an Artificial Family of Cytochromes P450."
Scientists are making great strides toward the creation of this new generation of personalized pharmaceuticals. On January 18, William A. Goddard III will discuss the progress that has been made and where it might lead in his talk "The Coming Revolution in Pharmaceuticals." Goddard is the Charles and Mary Ferkel Professor of Chemistry, Materials Science, and Applied Physics and director of the Materials and Process Simulation Center at the California Institute of Technology.
The talk, the final program of the 2005-06 Earnest C. Watson Lecture Series, will take place at 8 p.m. in Beckman Auditorium, 332 S. Michigan Avenue south of Del Mar Boulevard, on the Caltech campus in Pasadena. Seating is available on a free, no-ticket-required, first-come, first-served basis. Caltech has offered the Watson Lecture Series since 1922, when it was conceived by the late Caltech physicist Earnest Watson as a way to explain science to the local community.
For more information, call 1(888) 2CALTECH (1-888-222-5832) or (626) 395-4652. ###
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PASADENA, Calif.—If you can imagine the straw in your soda can being a million times smaller and made of carbon, you pretty much have a mental picture of a carbon nanotube. Scientists have been making them at will for years, but have never gotten the nanotubes to suck up liquid metal to form tiny wires. In fact, conventional wisdom and hundreds of refereed papers say that such is not even possible.
Now, with the aid of an 1875 study of mercury's electrical properties, researchers from the California Institute of Technology have succeeded in forcing liquid mercury into carbon nanotubes. Their technique could have important applications, including nanolithography, the production of nanowires with unique quantum properties, nano-sized plumbing for the transport of extremely small fluid quantities, and electronic circuitry many times smaller than the smallest in existence today.
Reporting in the December 2 issue of the journal Science, Caltech assistant professor of chemistry Patrick Collier and associate professor of chemical engineering Konstantinos Giapis describe their success in electrowetting carbon nanotubes. By "electrowetting" they mean that the voltage applied to a nanotube immersed in mercury causes the liquid metal to rise into the nanotube by capillary action and cling to the surface of its inner wall.
Besides its potential for fundamental research and commercial applications, Giapis says that the result is an opportunity to set the record straight. "We have found that when measuring the properties of carbon nanotubes in contact with liquid metals, researchers need to take into account that the application of a voltage can result in electrically activated wetting of the nanotube.
"Ever since carbon nanotubes were discovered in 1991, people have envisioned using them as molds to make nanowires or as nanochannels for flowing liquids. The hope was to have the nanotubes act like molecular straws," says Giapis.
However, researchers never got liquid metal to flow into the straws, and eventually dismissed the possibility that metal could even do so because of surface tension. Mercury was considered totally unpromising because, as anyone knows who has played with liquid mercury in chemistry class, a glob will roll around a desktop without wetting anything it touches.
"The consensus was that the surface tension of metals was just too high to wet the walls of the nanotubes," adds Collier, the co-lead author of the paper. This is not to say that researchers have never been able to force anything into a nanotube: in fact, they have, albeit by using more complex and less controllable ways that have always led to the formation of discontinuous wires.
Collier and Giapis enter the picture because they had been experimenting with coating nanotubes with an insulator in order to create tiny probes for future medical and industrial applications. In attaching nanotubes to gold-coated atomic force microscope tips to form nanoprobes, they discovered that the setup provided a novel way of making liquid mercury rise in the tubes by capillary action.
Casting far beyond the nanotube research papers of the last decade, the researchers found an 1875 study by Nobel Prize-winning physicist Gabriel Lippmann that described in detail how the surface tension of mercury is altered by the application of an electrical potential. Lippmann's 1875 paper provided the starting point for Collier and Giapis to begin their electrowetting experiments.
After mercury entered the nanotubes with the application of a voltage, the researchers further discovered that the mercury rapidly escaped from the nanotubes immediately after the voltage was turned off. "This effect made it very difficult to provide hard proof that electrowetting occurred," Collier said. In the end, persistence and hard work paid off as the results in the Science paper demonstrate.
Giapis and Collier think that they will be able to drive various other metals into the nanotubes by employing the process at higher temperature. They hope to be able to freeze the metal nanowires in the nanotubes so that they remain intact when the voltage is turned off.
"We can pump mercury at this point, but it's possible that you could also pump nonmetallic liquids," Giapis says. "So we now have a way of pumping fluids controllably that could lead to nanofluidic devices. We envision making nano-inkjet printers that will use metal ink to print text and circuitry with nanometer precision. These devices could be scaled up to operate in a massively parallel manner. "
The paper is titled "Electrowetting in Carbon Nanotubes." In addition to Collier and Giapis, the other authors are Jinyu Chen, a postdoctoral scholar in chemistry, and Aleksandr Kutana, a postdoctoral scholar in chemical engineering.


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accidents air pollution art arts censorship black lung bloggers Chongqing coal documentaries energy policy energy security greenhouse gas emissions Heilongjiang Hu Jie Hunan landslides lawsuits lung disease miners mine safety mining mining accidents occupational diseases occupational health slideshow Zhang Jianhua
Three Chinese Miners Rescued in HunanChinese state media has reported that a gas explosion in Hunan has killed seven people. Mining accidents in China occur frequently, and reports claim that the official death toll over the past ten years has reached over 47,000. From Asiaone: The explosion killed the miners on Sunday morning at the mine in Lianyuan city, though 39 others escaped, the official Xinhua news agency said, quoting the local government. Water rushed into the mine on Wednesday evening, trapping 16 miners
July 8, 2012 9:55 AM


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Policy: Locations Requiring Use of UVA Catering
|Date: 05/10/04
|Policy ID: FIN-007
|Status: Final
|Policy Type:
|Contact Office:
|Dining Services
|Oversight Executive:
|Vice President for Management and Budget
|Applies To:
|Academic Division, the Medical Center, and University-related Foundations.
|Table of Contents:
|Reason for Policy:
|Specifies the facilities where catering functions must be provided by University Catering Services. Describes the purpose and different uses for University Catering services.
|Policy Summary:
|Definition of Terms in Statement:
|Policy Statement:
University Dining Services, through its Catering Department, has the capability and facilities for providing catering services to departments, faculty, staff, students, officially sponsored or recognized organizations, other state agencies in the local area, and non-state organizations or firms providing a benefit or service to the University (e.g., recruiters on Grounds). Catering service is available on and off Grounds.
Departments wishing to use University Catering may make arrangements directly without using Procurement & Supplier Diversity Services' bid procedure.
University Catering service is the only caterer allowed to cater in the following locations:
|University Dining Services - Catering
|Related Information:
For more information on price lists, menus, etc., not covered in this policy, contact the University Catering Office, fourth floor Newcomb Hall, 924-7234.
See the Procurement & Supplier Diversity Services website for information related to contracting with non-University caterers.
|Policy Background:
|Major Category:
|Finance and Business Operations
|Category Cross Reference:
|Next Scheduled Review:
|Approved By, Date:
|Policy Review Committee, 05/10/04
|Revision History:
|Updated 4/7/11, 6/6/07.
|Supersedes (previous policy):
|Locations Requiring Use of UVa Catering VII.F.1


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Date: date unknown
Description: View down platform and two sets of railroad tracks towards depot. One man stands on the platform in the foreground. Two people are further down the tracks...
Date: 1927
Description: Old Soldiers' Reunion on the public square.
Description: Elevated view from bluff overlooking the railroad tracks and yard along the Mississippi River. A group of men are gathered on the track near stacks of lumb...
Description: Exterior of the Methodist Evangelical Church. Three children sit on the front steps.
Date: 1929
Description: View from entrance of a cave looking out to the Mississippi River, a railroad bridge, all surrounded by a forest. There is a small island in the river.
Date: 1925-08
Description: A view of the front of the Empire House Hotel, showing the porch and balcony. There are many wicker chairs on the porch, and there is an automobile parked...
Date: 1930
Description: View across railroad tracks of the Boscobel train depot. A wagon is parked on the platform. There is an advertisement for the circus painted on a wall at t...
Date: 1925
Description: View down railroad tracks of the National Zinc Separating Company grounds. There is a large mound of ores, railroad cars, industrial buildings and a tall b...
Description: View of men in the Kleinpel lumberyard posed in the midst of work. There are about two dozen men standing on wagons, inside buildings, and on a large stack...
Date: 1865 ca.
Description: Stereograph of a home in Lancaster.
Date: 1925 ca.
Description: An early two-story frame house with a lean-to addition on the rear.
Date: 1898
Description: Outdoor class group portrait of the 5th and 6th grades of Muscoda Public School. An "X" marks Emma Schmitt (the future Mrs. Sherwin Gillett). Boys kneel in...
Date: 1922
Description: View of Parker Hospital from the walkway. Leaves cover the lawn. There is a lawn swing in the yard.
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Date: 1920 ca.
Description: The Cassville Ferry with three cars and passengers, crossing the Mississippi River from Cassville to Turkey River, Iowa.
Description: Group portrait of children and their teacher posing on the lawn outside a clapboard school building. On the left side of the building is a stone foundation...
Date: 1923
Description: A busy street scene on Main Street and Wisconsin Avenue. Cars are parked in the middle of the street, and triangle flag banners hang above. The shops have...
Description: View across road of creamery building. Male workers are standing near the entrance on the left in front of a sign that says "Patch Grove Creamery." On the...
Date: 1911
Description: View down an unpaved street in the business district. The buildings along the street include: a pool room, restaurant, opera house, W.G. Baxter's dry goods...
Description: Jamestown students sitting and standing along a fence in front of clapboard one-room school building on a small hill.
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1. In a food processor, puree avocado with lime juice and lemon juice. Add broth, half-and-half, white pepper, and cumin. Puree until smooth and creamy. Season with salt to taste. Cover and refrigerate until well chilled, about 2 hours.
2. Stir together salsa and chicken. Ladle cold soup into 6 shallow bowls. Top each with about 1/2 cup chicken salsa.


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The Transportation Security Administration's new pat-down procedure involves what law enforcement officials describe as a hand-sliding motion rather than a traditional hand pat. The new technique is used when passengers opt out of the whole-body scan. The TSA is already using the procedure at some U.S. airports. Travelers will continue to receive the pat-downs from TSA agents who are the same gender as the traveler.
Published in Brief:


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San Jose Condo Rentals(12)
12 Results
Recent San Jose Reviews
Excellent stay
My family and I were in San Jose for a wedding and had a great stay at this property. Chris was prompt with his replies whenever we had questions and he was very helpful with talking us through getting the key fob for the gate upon our initial arrival. The condo was clean, airy and spacious enough for six adults, two teens and a toddler. We often had to be in and out of the property due to wedding activities so the easy parking situation and the central location was a big plus. We really appreciated the amenities, particularly the Keurig coffeemaker and the cookware. We'd highly recommend this property. It put a relaxing spin on an otherwise hectic wedding weekend. Thanks Chris!
Very Comfortable Condo!
My husband and I stayed at Daphne's condo on our recent short trip to San Jose. The condo was very comfortable and had everything we needed to feel at home! Daphne was very attentive to our needs! The condo was a short walk to Santana Row. We would definitely stay here if we ever vacation in San Jose again. Thanks Daphne for sharing your home with us!
Two weeks in Santana Row
The location was absolutely wonderful! Ginger was always available and responsive to questions and/or any issues that came up. One caution, we knew that it was a loft but the stairs were a bit more than what we were prepared to climb. The only real issue was that because of the total openness of the unit, if one of us wanted to go to bed earlier than the other, the TV or most of the lights could not stay on. The person going to bed later was relegated to reading in the small open bedroom on the lower floor.


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Winnipeg Free Press - ONLINE EDITION
Stadium cracks part of 'natural shrinkage'
Cracks in the concrete of Winnipeg's new football stadium are the result of "natural shrinkage" and will be maintained at no cost to the Winnipeg Football Club, said the chairman of the non-profit organization that owns the $200-million structure.
There are cracks on the concrete concourse and other areas of Investors Group Field, the new home of the Winnipeg Football Club and University of Manitoba Bisons, which opened earlier this month on the U of M's Fort Garry campus.
The cracks are not structural in nature and posed no concern to building inspectors, said a spokeswoman for the football club, which deferred questions about the concrete to stadium-builder Stuart Olson Dominion Construction and the stadium's owner, BBB Stadium Inc.
Cosmetic cracks on outdoor facilities can lead to more serious problems over time, given the long-term effects of moisture on concrete after a number of freeze-thaw cycles.
BBB Stadium chairman Phil Sheegl said the cracks will be maintained by Stuart Olson Dominion under the terms of a stadium-construction deal that came with a guaranteed maximum price. The football club will not be on the hook for those payments, said Sheegl, who's also chief administrative officer for the City of Winnipeg.
"It's all part of natural shrinkage," Sheegl said.
The province was the stadium's largest funder. The Selinger government fronted $160 million of the stadium's $200 million tab and also provided a $22.5-million grant to the project.
Manitoba Premier Greg Selinger says he's confident cracks the cracks can be addressed. "It doesn't sound like it's significant," he said Thursday morning following a provincial soccer-funding announcement in Winnipeg's Brooklands neighbourhood.
Stuart Olson Dominion has been asked to comment.
Updated on Thursday, June 20, 2013 at 12:30 PM CDT: updates with comments from Sheegl
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Welcome to LMTmag.com, the social and information hub of the dental lab industry. Connect with industry peers and vendors, ask questions, sign up for events, review products, read LMT articles and industry news and more!
November 17, 2011
- 1Upvote
get rid of metal and make offices switch to pressables or cad.
- 1Upvote
We've done our best to order smaller lots and send in scrap more frequently to minimize our exposure and risk to price fluctuations. With the price setting on the second London fix, we order alloy only on days the market is "up" and delay orders when the market is "down" and allow the lower price to...
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I find laboratories split on this issue. The oneâs who offered a fixed price product in the past, find themselves forced to change that model to accommodate the ever changing alloy prices and stay profitable, while others who offered their products at labor plus alloy cost in the past, are turning...
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Ivoclar has a noble alloy with 25% palladium, near the cost of base alloy called Callisto -CP Plus. With this the doctor can bill to insurance companies as noble with a higher return than base. I'm also doing a lot more e.max crowns.


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Sales of previously owned U.S. homes rose in April for the first time this year as the weather warmed, price increases slowed and more properties were put on the market. more
By Michelle Jamrisko
An index of Rhode Island's leading economic indicators produced by Providence Business News and e-forecasting.com fell in March for a second consecutive month, dropping one-tenth of a percent to 124.9 from 125 in February. more
By PBN Staff
Federal Reserve Bank of Philadelphia President Charles Plosser said the strongest U.S. economy in years, buoyed by a solid housing market, may push the jobless rate below 6 percent by year-end. more
By Jeff Kearns
The city has reached an agreement with the developer of the proposed South Street Landing project on three property tax stabilization deals that would generate $9.9 million in tax revenue over 15 years, Mayor Angel Taveras said Thursday. more
By Patrick Anderson
It's back to square one for Rhode Island's redevelopment of the former Shooters nightclub property in Providence. The R.I. Department of Environmental Management officially broke off talks May 1 with Bowl Arts LLC, the community group that had been hoping to build a concert and performing arts venue on the site. more
By Patrick Anderson
Prices for single-family homes climbed in 74 percent of U.S. cities in the first quarter, fewer than a year earlier, as the nation's housing rebound cools. more
By Prashant Gopal
Bristol County, Mass., foreclosure starts climbed 94.6 percent in March compared with the same period last year, The Warren Group said Thursday. more
By PBN Staff
The Providence-Warwick metro area saw single-family home prices increase 9 percent in March compared with the same month last year, according to the CoreLogic Home Price Index report released Tuesday. more
By PBN Staff
The Interstate 195 Redevelopment District Commission has loosened its confidentiality policy and will now identify all proposals for the former highway land, not just winning bids, the commission announced Monday. more
By Patrick Anderson
Capital Properties Inc. reported first-quarter net income of $77,000, or 1 cent per share, a 77.4 percent decline from the $340,000, or 5 cents per share, recorded during the same period a year earlier. more
By PBN Staff


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Sign in to digital edition
Thursday 2 Apr 2015
By Martin Bailey. Museums, Issue 242, January 2013Published online: 08 January 2013
An important painting by Miró was damaged in 2011 while on loan to Tate Modern, in an incident that went unreported in the media. The work was on loan from the Fundació Joan Miró in Barcelona and the cost of repairs and depreciation was £203,000, which is revealed in figures obtained by The Art Newspaper on government indemnity.
According to a visitor to the Miró retrospective, a man leant against the picture with both hands. A spokeswoman for the Tate says that the gallery believes it was an accident. None of the gallery's staff witnessed the incident. Painting on White Background for the Cell of a Recluse I, 1968 (above), is part of a room-sized triptych, and the left-side picture is 3.5m long. The incident occurred on 7 July 2011 and the painting went back on display eight days later, after conservation work was completed by the Tate with advice from the Miró foundation. The conservation work would have cost a few thousand pounds, so the £203,000 indemnity payment by the UK government was mainly compensation for depreciation in its value. As its title suggests, the acrylic on canvas is largely white, with a wiggling black line. Although conservation masks the damage, the repair is still just barely visible.After London, the Miró retrospective travelled to Barcelona. It closed in August 2012 at the National Gallery of Art in Washington, DC, where the damaged painting was not shown.Tate Modern has around 5 million visitors a year. In October 2012, a 26-year-old man scrawled a slogan on one of Mark Rothko's Seagram murals, Black on Maroon, 1958, which is in the Tate's collection. In December, the vandal, Wlodzimierz Umaniec (also known as Vladimir Umanets), who is Polish-born and British-based, was sentenced to two years' imprisonment for criminal damage.
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The Western Riverside Council of Governments is the means by which local government works together to strengthen Western Riverside County's voice in our region, our state, and our nation.
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Our special coverage of the closest race for years
Explore the personal stories of Syrian refugees in Lebanon
21 Jul 2010 05:03 GMT
'Pose a threat'"The most important lesson for all of us in the intelligence community from this year's provocations by Pyongyang is to realise that we may be entering a dangerous new period when North Korea will once again attempt to advance its internal and external political goals through direct attacks on our allies in the Republic of Korea," Clapper wrote."Coupled with this is a renewed realisation that North Korea's military forces pose a threat that cannot be taken lightly."
Clapper, who currently serves as intelligence adviser to Robert Gates, the defence secretary, as well as the Pentagon's liaison to the director of national intelligence, was a top defence official dealing with North-South tensions on the Korean Peninsula in the 1980s, at a time when he said violent provocations by Pyongyang were more common than during the last decade.
Tensions between North and South Korea remain high following the March sinking of the South Korean naval vessel, Cheonan, killing 46 South Korean sailors.
Pyongyang has denied responsibility and escaped censure this month from the United Nations, which condemned the attack but did not explicitly blame North Korea.
Military exercises
Gates, on a visit to South Korea, and Kim Tae-young, the South's defence minister, announced a major military exercise on Sunday in the Sea of Japan.
Roger Wilkison reports on the extent of private sector involvement in US intelligence
The drill will involve some 20 ships, including the 97,000-tonne aircraft carrier USS George Washington and some 200 fixed-wing aircraft, according to military officials.
North Korea denounced the drill as "very dangerous sabre-rattling".
It is "aimed at further straining the already deadlocked inter-Korean relations and igniting a nuclear war against the DPRK [North Korea], while watching for a chance," the Minju Joson, North Korea's cabinet newspaper, said in a commentary.
Gates also announced that he and Hillary Clinton, the US secretary of state, would visit the Demilitarised Zone (DMZ) on Wednesday.
Clinton, whose husband Bill Clinton called the DMZ "the scariest place on earth" when he visited as US president in 1993, said the trip was meant to show solidarity with Seoul after the sinking of the Cheonan.
"It's particularly timely to show our strong support for South Korea, a stalwart ally, and to send a very clear message to North Korea," Clinton told reporters ahead of her trip.
Clinton and Gates are expected to arrive in the morning at the DMZ, the no-man's land between the two Koreas and the last Cold War flashpoint.
'Volatile region'
Gates, speaking to reporters at a US military base just south of the DMZ on Tuesday, said the trip was "a useful reminder that we are in an armistice and that this is a volatile region, as we saw with the Cheonan".
The armistice signed in 1953 halted fighting between US-led UN forces backing South Korea on one side, and Chinese and North Korean troops on the other.
But the truce has never been converted into a peace treaty, leaving the two Koreas technically still at war.
Despite the strong rhetoric, US defence and intelligence officials acknowledge options are limited in dealing with North Korea.
And Pyongyang meanwhile has recently signalled it wants a return to talks with regional powers on its nuclear programme.
Analysts say Washington and Seoul are reluctant to head back into the nuclear talks, which the North has previously used to extract benefits from the international community while still pressing ahead with efforts to develop a nuclear arsenal.
But they may have little choice with Washington nervous about North Korea's potential to export atomic weapons.
Source: Agencies
Allegiance to Pyongyang makes for uneasy relationship with host nation.
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USS George Washington joins naval exercises amid raised tensions on Korean peninsula.
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For a stunning accent chair, the Tango leather lounge chaise is both sensuous and striking. Casa Novalia take Italian craftsmanship and experience with fine leathers and create a high quality chair of fabulous character. The Tango features a swooping arched frame that lets you recline in ergonomic comfort. Topped with leather cushions, the Tango has a nearly woven effect in its buttoned padding. Made of the finest leathers, the Tango has been carefully crafted down to the smallest detail. The Leather grains have been carefully chosen to compliment each other, while harmonious threads are used to blend into the smooth surface. And with all this sensuous luxury you also get a chair that is easy to clean and maintain. A fabulous piece from Casa Novalia the Tango contemporary chaise offers modern elegance and refinement.
Posted in Chaise Lounges on December 20, 2006 11:41 PM
very interested in purchasing this chaise please
Send my the information
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Reason 7 – Product Presentation
Last week Sonic State had a visit from Ryan Harlin – he's the guy behind Propellerheads Music Making Month and also puts together the ongoing video content for Propellerheads.
"He showed us around the new features in the just released Reason 7, including (finally) the introduction of MIDI, some neat mixer functions – Spectrum EQ, bussing and parallel processing, plus the new audio processing module – Audiomatic."
Reason Has a Rack for That – new R7 show off from the Propellerhead guys
New video merely stating the obvious I guess
Try Reason: http://www.propellerheads.se/tryreason
Reason is Propellerhead Software's flagship music production platform; a virtual studio rack full of synths, drum machines, samplers, and effects like reverb, delay, distortion, and much more. Add that all together with unlimited audio recording, legendary audio slicing/stretching, a professional mixer modelled after a big-studio classic… and you've got a powerhouse of a program with one central focus: making your music better than ever.
Whatever your music needs, Reason has a rack for that.
Music in this video: Syndrome by Mikkas: http://www.mikkasmusic.com/
Appearances by:
Jakwob – http://twitter.com/jakwob
Felix Cartal – http://www.felixcartal.com
Lucky Date – http://luckydateofficial.com
Reason has a rack for everything
The big mixer in Reason is where your songs really find their full potential – sonically speaking. The powerful EQ, channel dynamics, bus channels, parallel channels, spectrum EQ, and oh-so-lovely Master Bus Compressor are all designed with one thing in mind: making you sound great!
In this walkthrough of the big mixer, we take a look at the major sections of the mixer and what they mean for your mix.
This video features "Outside In" by Atom, mixed by Gary Bromham inside Reason 7. The track is available for download as a Reason demo song here:
Reason's virtual rack is the heart and soul of Reason. Synths, drum machines, samplers, effects, and little gadgets that tweak and freak one another are the building blocks of your music.
In this walk-through, we check out the Reason rack in more detail and get you up to speed on the powerful tools in your toolbox.
This video features "Syndrome" by Mikkas and "Bobo by Schpilka:
Inspiration can be a tricky thing. You either feel it or you don't. So much of music making is about either capturing inspiration when it happens or making it happen through new sounds, new techniques, or new ways of processing sound.
In this video, we take a look at all the ways that Reason can inspire your music.
This video features "Be Like You" by Olivia Broadfield and "English" by Ali Payami:
Reason 7 has been officially released
Today Propellerhead has released their latest incarnation of their popular DAW – Reason 7
Reason 7 brings tons of new improvements for the mixer, the rack and the sequencer. Integrate your instruments into Reason with MIDI out, audio slicing and audio quantize. Turn your recordings into REX loops. For mixing, we're introducing a spectrum analyzer with visual EQ, group and parallel channels and workflow improvements. To inspire, Reason 7 imports audio from your music library and web formats. The enhanced Factory Sound Bank comes fully loaded with tons of new loops and drum kits. The new Audiomatic Retro Transformer effect adds a futuristic-vintage sound to any tracks.
Reason Essentials 2 is a free upgrade for all owners of Reason Essentials, bringing audio slicing and quantizing to the sequencer. Create REX files from your recordings directly in Reason Essentials. Import audio files from your music library and the web with improved file format support. Workflow enhancements in the rack and sequencer make writing, producing and mixing music in Reason Essentials even faster, easier and more fun.
All details can be found here >>
Propellerhead Reason 7 has been announced
Propellerhead has announced a new major version of its Reason music software. With over 90 third party Rack Extensions expanding Reason's rack of instruments and effects already available, Propellerhead has focused its attention on new creative and inspirational improvements for the mixer, the rack and the sequencer.
With Reason 7, users can integrate all their instruments into Reason with MIDI out, automatic audio slicing and audio quantize, and even convert their recordings into REX loops for further creative possibilities in the rack. For mixing, Propellerhead is introducing a spectrum analyzer with visual EQ controls; group and parallel mix channels; and many workflow improvements to help users sound better, easier. To inspire, Reason 7 makes it easier to import audio from users' music libraries and the web with support for mp3, aac, wma and more. The enhanced Factory Sound Bank comes fully loaded with tons of new loops and drum kits, while the new Audiomatic Retro Transformer effect unit adds a futuristic-vintage sound to any tracks, never more than a mouse-click away.
Reason users are invited to sign up for the limited public beta testing at the Propellerhead web site.
Pricing & Availability
Reason 7 and Reason Essentials 2 begin limited public beta testing today and will be available for purchase worldwide in Q2 of 2013 at the following suggested retail pricing:
- Reason 7 €405 / $449.
- Reason Essentials 2 €120 / $129.
- Reason 7 Upgrade (from any previous Reason version) €129 / $129.
- Reason Essentials 2 upgrade from previous versions free.
- Balance (includes upgrade to Reason 7 for owners of previous versions of Reason) €429 / $449.
Propellerhead is also offering a grace period for purchasers of current versions of Reason, Reason Essentials and the Balance audio interface. Purchasing and registering a qualifying product today makes users eligible for a free upgrade to Reason 7. For details see: www.propellerheads.se/freeupgrade
Reason: Music in the Kitchen
Mixed and Arranged entirely inside Propellerhead's Reason 6.5 with sounds sampled in my kitchen!!
The ingredients were as follows
A glass bottle to blow air across the top (if its a bottle of alcohol – music automatically gets made)
Microwave (button sounds, door bang, start/stop)
Kitchen Timer
Cabinet drawers and doors
Sink tap, Sink hose spurting water
Refrigerator water dispenser (water falling and the mechanical switch you press your glass against)
Dishwasher switches and lock
2 different blenders
Water falling into a pre-heated pot for that sizzling sound
The crunch of the wrapper of a fiber bar
Almonds falling into a box
Groundnuts in a box
Pulses/Rice in a box
A bunch of empty containers, pots and pans
Running my fingers around the rims of glass
Rice cooker switch
…the missing ingredient I could not shoot – the 'insinkerator' going on and off.
So what's the recipe then? Mix it till it sounds good. And if it sounds good, it is good.
I had a lot of fun making this. I hope you had fun watching and listening!
Reason DAW: Malström Sound Design – Micro Tutorial
More info on Reason: https://www.propellerheads.se/product…
Malström is a one-of-a-kind synth, begging to be explored. In this tutorial we'll learn the basics of this mean green machine by creating a synth pad sound from scratch. And once you've got a feel for what Malström can do, endless sound design possibilities are just around the corner!
Propellerhead Figure with Audiobus
"nice! nice update! Splendid sound quality. Splendid version upgrade"
What's New in Version 1.4
• SoundCloud Sharing – share your Figure tracks with access to Facebook, Twitter and more
• Introducing Audiobus support: Now you can stream live audio directly to other Audiobus-compatible apps! See http://audiob.us for more information
Figure from Propellerhead gets AudioBus and SoundCloud sharing support
Propellerhead has updated Figure for iOS, adding some frequently requested features, like SoundCloud and AudioBus support.
Here's what's new in Figure 1.4:
- SoundCloud Sharing – share your Figure tracks with access to Facebook, Twitter and more
- Audiobus support: Now you can stream live audio directly to other Audiobus-compatible apps
- Background audio (in device Settings)
- Sort song list by Name/Date
- Bug fixes and performance improvements
Figure is $.99 in the app store >>
The nitty gritty details:
• Bass & lead parts use Reason's Thor synthesizer
• Drums powered by Reason's Kong drum machine
• Play in different keys & modes. Set once or change on the fly.
• Increase the Shuffle to loosen up your beats
• Turn up Pump to add a club sound to your tracks
• Adjust levels using Propellerhead's legendary mixer
• Save, browse and load song files
• Set length of loop (1,2,4,8 bars)
• Export audio to iTunes File Sharing
M83 Midnight City – cover using the Reason DAW
Background video description:
This is my version of M83's "Midnight City", recreated (a "ReCover" as I call it) completely in Propellerhead's Reason. All custom patches, all original note data (no web download of MIDI files).


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Pronunciation: (glob'yu-lin), Strict Standards: Non-static method FenSites::linkTo() should not be called statically in /site/html/dictionary/globulin.html on line 73 [key]
—n. Biochem.
1. any of a group of proteins, as myosin, occurring in plant and animal tissue, insoluble in pure water but soluble in dilute salt solutions and coagulable by heat.
2. any of several groups of blood plasma proteins, divided into fractions, as alpha, beta, or gamma globulin, depending on electrophoretic mobility.
Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease.
See also:


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The Happiness Hypothesis: Finding Modern Truth in Ancient Wisdom
Basic Books, 2006 - Psychology - 297 pages
Jonathan Haidt skillfully combines two genres-philosophical wisdom and scientific research-delighting the reader with surprising insights. He explains, for example, why we have such difficulty controlling ourselves and sticking to our plans; why no achievement brings lasting happiness, yet a few changes in your life can have profound effects, and why even confirmed atheists experience spiritual elevation. In a stunning final chapter, Haidt addresses the grand question "How can I live a meaningful life?," offering an original answer that draws on the rich inspiration of both philosophy and science.
╩"The Happiness Hypothesisis a wonderful and nuanced book that provides deep insight into the some of the most important questions in life--Why are we here?╩ What kind of life should we lead?╩ What paths lead to happiness?╩ From the ancient philosophers to cutting edge scientists, Haidt weaves a tapestry of the best and the brightest.╩ His highly original work on elevation and awe--two long-neglected emotions--adds a new weave to that tapestry.╩ A truly inspiring book."╩ -David M. Buss, author ofThe Evolution of Desire:╩ Strategies of Human Mating ╩ ęIn this beautifully written book, Jonathan Haidt shows us the deep connection that exists between cutting-edge psychological research and the wisdom of the ancients.╩ It is inspiring to see how much modern psychology informs life's most central and persistent questions -Barry Schwartz, author ofThe Paradox of Choice: Why More Is Less ╩ ╩ęIn our quest for happiness, we must find a balance between modern science and ancient wisdom, between East and West, and between įleft brainš and įright brain.š Jon Haidt has struck that balance perfectly, and in doing so has given us the most brilliant and lucid analysis of╩virtue and well-being in the entire literature of positive psychology.╩ For the reader who seeks to understand happiness, my advice is: Begin with Haidt.ė -Martin E.P. Seligman, Director, Positive Psychology Center at the University of Pennsylvania and author ofAuthentic Happiness ╩ ęHaidt is a fine guide on this journey between past and present, discussing the current complexities of psychological theory with clarity and humor. . . Haidtšs is an open-minded, robust look at philosophy, psychological fact and spiritual mystery, of scientific rationalism and the unknowable ephemeral ą an honest inquiry that concludes that the best life is, perhaps, one lived in the balance of opposites.ė -Bookpage
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Some good insight into the human condition - Goodreads
The introduction is the most valuable. - Goodreads
Another great overview. - Goodreads
Clear and insightful prose. - Goodreads
It is well researched, very coherent. - Goodreads
Lots of great gems of insights. - Goodreads
Review: The Happiness Hypothesis: Finding Modern Truth in Ancient WisdomUser Review - Bradley Chasse - Goodreads
It was good, I'll read it again. Read full review
Review: The Happiness Hypothesis: Finding Modern Truth in Ancient WisdomUser Review - John Gallegos - Goodreads
Some great finds in this analysis of happiness as seen through the eyes of science and time. Not as cut and dry as I had heard it was going to be. I would go as far as saying that the title is a bit ... Read full review
References to this book
Handbook of Emotions, Third Edition
Michael Lewis,Jeannette M. Haviland-Jones,Lisa Feldman Barrett
Limited preview - 2008
All Book Search results »
Leadership and Business Ethics
Gabriel Flynn
Limited preview - 2008


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About StumbleDNA StumbleDNA
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Book your room at Hotel Hillarys
Hotel in Osaka (Namba) near Tsutenkaku Tower
This hotel is located in Osaka (Namba), close to Sennichimae Doguyasuji Shopping Street, Tsutenkaku Tower, and Shitennoji Temple. Also nearby are Shinsaibashi Shopping Arcade and Osaka Museum of History.
Hotel Features
In addition to a restaurant, Hotel Hillarys features complimentary high-speed (wired) Internet access. Other amenities include dry cleaning/laundry services and laundry facilities.
Room Amenities
In addition to plasma televisions with digital channels, guestrooms include complimentary high-speed (wired) Internet access. Bathrooms come with shower/tub combinations and bidets.Information missing or incorrect? Tell us!
Hotel Amenities
Hotel Amenities
The hotel offers a restaurant. Public areas are equipped with complimentary wired high-speed Internet access. This Japanese business hotel also offers multilingual staff, laundry facilities, and dry cleaning/laundry services. Parking is available onsite for a surcharge.
- Total number of rooms - 148
- Number of floors - 8
- Dry cleaning/laundry service
- Elevator/lift
- Express check-out
- Free wired high-speed Internet
- 24-hour front desk
- Restaurant
- Laundry facilities
- Multilingual staff
- Self parking (surcharge)
- Number of buildings/towers - 1
Available in all rooms: Free wired high-speed Internet
Available in some public areas: Free wired high-speed Internet
Self parking (surcharge)
Room Amenities
- Pay movies
- Premium bedding
- Separate sitting area
- Air conditioning
- Climate control
- Refrigerator
- Private bathroom
- Free toiletries
- Hair dryer
- Bidet
- In-room massage available
- Slippers
- Shower/tub combination
- Desk
- Blackout drapes/curtains
- Digital TV service
- Free wired high-speed Internet
- Pillow menu
- Plasma TV
Where to Eat
Anna Colors Coffee - This café serves breakfast, brunch, and lunch.
Nearby Things to Do
The recreational activities listed below are available either on site or nearby; fees may apply.
- Scooter/moped rentals nearby
- Bicycle rentals on site
Hotel Policies
Check-in time starts at 3 PM
Check-out time is 10 AM
Payment types
You need to know
Extra-person charges may apply and vary depending on hotel policy.
This property accepts up to 2 pieces of baggage before check-in. Baggage is accepted no earlier than 1 day prior to check-in date and must bear the name of the guest. For more details, please contact the office using the information on the reservation confirmation received after booking.
- Self parking fee: JPY 1500 per night
We should mention
Children 6 years old and younger stay free when occupying the parent or guardian's room, using existing bedding. The Japanese Ministry of Health, Labour, and Welfare requires all international visitors to submit their passport number and nationality when registering at any lodging facility (inns, hotels, motels, etc. ). Additionally, lodging proprietors are required to photocopy passports for all registering guests and keep the photocopy on file.


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The Press Newspaper
The Press Newspaper
The Lake Township trustees heard a report Tuesday from Dan McLargin, road supervisor, that an application for a grant to pay for replacing a stretch of Libbey Road has been submitted to the Ohio Department of Transportation and the Ohio Turnpike and Infrastructure Commission.
A fundraiser is currently under way to benefit the Lake High School After Prom, a drug- and alcohol-free event, as well as other drug awareness programs at Lake.
On Jan. 14, the Ottawa County Commissioners recognized Ottawa County veteran William "Bill" Sorg, of American Legion Post 279, Elmore.
National Guard halts turbine project at Camp Perry
A letter of intent to sue the Ohio National Guard and an on-going petition effort were enough to convince federal officials to at least temporarily halt plans for constructing a wind turbine at Camp Perry near Oak Harbor.
The American Bird Conservancy and Black Swamp Bird Observatory last week were praising the decision by the National Guard Bureau office in Maryland to withdraw a key finding to the project effective immediately.
A "green" opportunity for the Village of Oak Harbor turned faces red at a recent meeting of village council.
Newly-seated councilmember Sue Rahm was upset that an Efficiency Smart Schedule program turned down by council late last year was once again on the meeting agenda for approval.
When she asked why it was again on the agenda, Mayor Bill Eberle said he had it placed there.
Speed Limit
Do you think 75 mph is a good speed limit for the Ohio Turnpike and rural highways?
Yes (20 Votes)
No (11 Votes)
424208412 [{"id":"44","title":"Yes","votes":"20","pct":64.52,"type":"x","order":"1","resources":[]},{"id":"45","title":"No","votes":"11","pct":35.48,"type":"x","order":"2","resources":[]}] ["#194e84","#3b6b9c","#1f242a","#37414a","#60bb22","#f2babb"] sbar 160 160 /component/communitypolls/vote/19-speed-limit No answer selected. Please try again. Thank you for your vote. Answers Votes